Science.gov

Sample records for reproducible gastrointestinal complaints

  1. Gastrointestinal complaints during exercise: prevalence, etiology, and nutritional recommendations.

    PubMed

    de Oliveira, Erick Prado; Burini, Roberto Carlos; Jeukendrup, Asker

    2014-05-01

    Gastrointestinal problems are common, especially in endurance athletes, and often impair performance or subsequent recovery. Generally, studies suggest that 30-50% of athletes experience such complaints. Most gastrointestinal symptoms during exercise are mild and of no risk to health, but hemorrhagic gastritis, hematochezia, and ischemic bowel can present serious medical challenges. Three main causes of gastrointestinal symptoms have been identified, and these are either physiological, mechanical, or nutritional in nature. During intense exercise, and especially when hypohydrated, mesenteric blood flow is reduced; this is believed to be one of the main contributors to the development of gastrointestinal symptoms. Reduced splanchnic perfusion could result in compromised gut permeability in athletes. However, although evidence exists that this might occur, this has not yet been definitively linked to the prevalence of gastrointestinal symptoms. Nutritional training and appropriate nutrition choices can reduce the risk of gastrointestinal discomfort during exercise by ensuring rapid gastric emptying and the absorption of water and nutrients, and by maintaining adequate perfusion of the splanchnic vasculature. A number of nutritional manipulations have been proposed to minimize gastrointestinal symptoms, including the use of multiple transportable carbohydrates, and potentially the use of nutrients that stimulate the production of nitric oxide in the intestine and thereby improve splanchnic perfusion. However, at this stage, evidence for beneficial effects of such interventions is lacking, and more research needs to be conducted to obtain a better understanding of the etiology of the problems and to improve the recommendations to athletes.

  2. Ethnomedicinal Evaluation of Medicinal Plants Used against Gastrointestinal Complaints

    PubMed Central

    Tariq, Akash; Mussarat, Sakina; Adnan, Muhammad; Abd_Allah, E. F.; Hashem, Abeer; Alqarawi, Abdulaziz Abdullah

    2015-01-01

    Aim of the present study was to document ethnomedicinal plants used against gastrointestinal complaints in five selected remote regions of Pakistan and to select potential medicinal plants for further in vitro and in vivo investigation. Data on ethnomedicinal plants and ethnographic profile of respondents was documented using semistructured questionnaires. The present study revealed utilization of 52 medicinal plants for the treatment of different gastrointestinal infections in studied regions. Apiaceae was the most dominant family reported to be used for the treatment of these infections (4 plants). Among all the plant parts fruit (24%), whole plants and leaves (23% each) were the most preferred plant parts used by the healers. Dosage of recipe was found to be related with the age of the patient. Highest degree of informant consensus was reported for vomiting, nausea (0.92 each), abdominal pain (0.9), and diarrhea (0.89). Withania coagulans scored highest FL value (86%) followed by Mentha longifolia and Melia azadirachta ranked second with FL value (75% each). Young generation was found to possess little traditional knowledge about utilizing plant recipes against these infections. Plants with high Fic and FL values should be subjected for further phytochemical and pharmacological investigation for scientific validation. PMID:26114117

  3. Gastrointestinal complaints related to eating and drinking habits and work life of intensive care nurses in Zonguldak, Turkey.

    PubMed

    Celik, Sevim; Veren, Funda; Ocakci, Ayse

    2008-01-01

    The purpose of this descriptive study was to determine the effect of self-reported work life and nutritional habits of intensive care unit nurses in the incidence of gastrointestinal complaints. This study of 110 nurses found that long work hours at night and incorrect eating and drinking habits affect their gastrointestinal system.

  4. Frequency of enteric protozoan parasites among patients with gastrointestinal complaints in medical centers of Zahedan, Iran.

    PubMed

    Haghighi, Ali; Khorashad, Alireza Salimi; Nazemalhosseini Mojarad, Ehsan; Kazemi, Bahram; Rostami Nejad, Mohammad; Rasti, Sima

    2009-05-01

    We investigated the prevalence of intestinal protozoan parasites in patients with gastrointestinal complaints in medical centers in Zahedan, Iran. A total of 1562 stool samples was examined from July 2004 to January 2006 using microscopy (direct smear, formalin-ether concentration), xenic culture and PCR techniques. Four hundred and twenty-seven (27.3%) of the patients were infected with one or more intestinal parasites. Giardia lamblia (10.1%), Entamoeba coli (10%), E. hartmanni (1.7%), Blastocystis hominis (2.2%), Chilomastix mesnili (1.7%), Trichomonas hominis (0.7%), E. histolytica/E. dispar (0.51%) and Iodamoeba butschlii (0.45%) were the most prevalent protozoa detected with microscopy. Of the eight microscopy-positive E. histolytica/E. dispar samples, six were identified as E. dispar by PCR/gel electrophoresis, whereas E. histolytica was not detected at all. Although Zahedan is an area with poor hygiene located in a tropical area near the border of Pakistan and Afghanistan, the prevalence of E. histolytica and E. dispar here compared with other parasites and infectious diseases is unexpectedly low. PMID:19084249

  5. Weight gain in anorexia nervosa does not ameliorate the faecal microbiota, branched chain fatty acid profiles, and gastrointestinal complaints

    PubMed Central

    Mack, Isabelle; Cuntz, Ulrich; Grämer, Claudia; Niedermaier, Sabrina; Pohl, Charlotte; Schwiertz, Andreas; Zimmermann, Kurt; Zipfel, Stephan; Enck, Paul; Penders, John

    2016-01-01

    The gut microbiota not only influences host metabolism but can also affect brain function and behaviour through the microbiota-gut-brain axis. To explore the potential role of the intestinal microbiota in anorexia nervosa (AN), we comprehensively investigated the faecal microbiota and short-chain fatty acids in these patients before (n = 55) and after weight gain (n = 44) in comparison to normal-weight participants (NW, n = 55) along with dietary intake and gastrointestinal complaints. We show profound microbial perturbations in AN patients as compared to NW participants, with higher levels of mucin-degraders and members of Clostridium clusters I, XI and XVIII and reduced levels of the butyrate-producing Roseburia spp. Branched-chain fatty acid concentrations, being markers for protein fermentation, were elevated. Distinct perturbations in microbial community compositions were observed for individual restrictive and binge/purging AN-subtypes. Upon weight gain, microbial richness increased, however perturbations in intestinal microbiota and short chain fatty acid profiles in addition to several gastrointestinal symptoms did not recover. These insights provide new leads to modulate the intestinal microbiota in order to improve the outcomes of the standard therapy. PMID:27229737

  6. [The prevalence of intestinal parasites in children brought to the Kars Maternal and Children's Hospital with complaints of gastrointestinal symptoms].

    PubMed

    Arslan, Mükremin Ozkan; Sari, Bariş; Kulu, Bahar; Mor, Neriman

    2008-01-01

    This study was carried out to determine the prevalence of intestinal parasites in 2-6 year-old children who were brought to Kars Maternal and Children's Hospital with complaints of gastrointestinal symptoms during March-June 2007. Fecal samples were taken from children and brought to the parasitology laboratory of the Faculty of Veterinary Medicine to be examined for intestinal parasites. Fecal samples were examined by centrifugal formalin ether, zinc-sulphate floatation, and modified acid fast techniques. Lugol solution was used during microscopic examination and suspected samples were also examined by the Giemsa dye technique. The prevalence of intestinal parasites in children was found to be 36.2% (50/138). Protozoan and helminth parasites were found to be 34.1% (47/138) and 2.9% (4/138) in the fecal samples examined, respectively. Giardia intestinalis (10.9%), Entamoeba histolytica/dispar (10.1%), Entamoeba coli (8%), Blastocystis hominis (6.5%), Endolimax nana (4.3%), Chilomastix mesnili (1.4%), Ascaris lumbricoides (1.4%), Entamoeba hartmanni (0.7%), Cyclospora cayetanensis (0.7%), Enterobius vermicularis (0.7%) and Hymenolepis nana (0.7%) were identified from the feces of children of Kars and vicinity. No Cryptosporidium spp. was detected. PMID:18985583

  7. Setup Reproducibility for Thoracic and Upper Gastrointestinal Radiation Therapy: Influence of Immobilization Method and On-Line Cone-Beam CT Guidance

    SciTech Connect

    Li, Winnie; Moseley, Douglas J.; Bissonnette, Jean-Pierre; Purdie, Thomas G.; Bezjak, Andrea; Jaffray, David A.

    2010-01-01

    We report the setup reproducibility of thoracic and upper gastrointestinal (UGI) radiotherapy (RT) patients for 2 immobilization methods evaluated through cone-beam computed tomography (CBCT) image guidance, and present planning target volume (PTV) margin calculations made on the basis of these observations. Daily CBCT images from 65 patients immobilized in a chestboard (CB) or evacuated cushion (EC) were registered to the planning CT using automatic bony anatomy registration. The standardized region-of-interest for matching was focused around vertebral bodies adjacent to tumor location. Discrepancies >3 mm between the CBCT and CT datasets were corrected before initiation of RT and verified with a second CBCT to assess residual error (usually taken after 90 s of the initial CBCT). Positional data were analyzed to evaluate the magnitude and frequencies of setup errors before and after correction. The setup distributions were slightly different for the CB (797 scans) and EC (757 scans) methods, and the probability of adjustment at a 3-mm action threshold was not significantly different (p = 0.47). Setup displacements >10 mm in any direction were observed in 10% of CB fractions and 16% of EC fractions (p = 0.0008). Residual error distributions after CBCT guidance were equivalent regardless of immobilization method. Using a published formula, the PTV margins for the CB were L/R, 3.3 mm; S/I, 3.5 mm; and A/P, 4.6 mm), and for EC they were L/R, 3.7 mm; S/I, 3.3 mm; and A/P, 4.6 mm. In the absence of image guidance, the CB slightly outperformed the EC in precision. CBCT allows reduction to a single immobilization system that can be chosen for efficiency, logistics, and cost. Image guidance allows for increased geometric precision and accuracy and supports a corresponding reduction in PTV margin.

  8. Reproducibility blues.

    PubMed

    Pulverer, Bernd

    2015-11-12

    Research findings advance science only if they are significant, reliable and reproducible. Scientists and journals must publish robust data in a way that renders it optimally reproducible. Reproducibility has to be incentivized and supported by the research infrastructure but without dampening innovation. PMID:26538323

  9. Reproducibility blues.

    PubMed

    Pulverer, Bernd

    2015-11-12

    Research findings advance science only if they are significant, reliable and reproducible. Scientists and journals must publish robust data in a way that renders it optimally reproducible. Reproducibility has to be incentivized and supported by the research infrastructure but without dampening innovation.

  10. Reproducible Science▿

    PubMed Central

    Casadevall, Arturo; Fang, Ferric C.

    2010-01-01

    The reproducibility of an experimental result is a fundamental assumption in science. Yet, results that are merely confirmatory of previous findings are given low priority and can be difficult to publish. Furthermore, the complex and chaotic nature of biological systems imposes limitations on the replicability of scientific experiments. This essay explores the importance and limits of reproducibility in scientific manuscripts. PMID:20876290

  11. Elusive reproducibility.

    PubMed

    Gori, Gio Batta

    2014-08-01

    Reproducibility remains a mirage for many biomedical studies because inherent experimental uncertainties generate idiosyncratic outcomes. The authentication and error rates of primary empirical data are often elusive, while multifactorial confounders beset experimental setups. Substantive methodological remedies are difficult to conceive, signifying that many biomedical studies yield more or less plausible results, depending on the attending uncertainties. Real life applications of those results remain problematic, with important exceptions for counterfactual field validations of strong experimental signals, notably for some vaccines and drugs, and for certain safety and occupational measures. It is argued that industrial, commercial and public policies and regulations could not ethically rely on unreliable biomedical results; rather, they should be rationally grounded on transparent cost-benefit tradeoffs. PMID:24882687

  12. Elusive reproducibility.

    PubMed

    Gori, Gio Batta

    2014-08-01

    Reproducibility remains a mirage for many biomedical studies because inherent experimental uncertainties generate idiosyncratic outcomes. The authentication and error rates of primary empirical data are often elusive, while multifactorial confounders beset experimental setups. Substantive methodological remedies are difficult to conceive, signifying that many biomedical studies yield more or less plausible results, depending on the attending uncertainties. Real life applications of those results remain problematic, with important exceptions for counterfactual field validations of strong experimental signals, notably for some vaccines and drugs, and for certain safety and occupational measures. It is argued that industrial, commercial and public policies and regulations could not ethically rely on unreliable biomedical results; rather, they should be rationally grounded on transparent cost-benefit tradeoffs.

  13. Gastrointestinal Motility Disorders in Children

    PubMed Central

    Ambartsumyan, Lusine

    2014-01-01

    The most common and challenging gastrointestinal motility disorders in children include gastroesophageal reflux disease (GERD), esophageal achalasia, gastroparesis, chronic intestinal pseudo-obstruction, and constipation. GERD is the most common gastrointestinal motility disorder affecting children and is diagnosed clinically and treated primarily with acid secretion blockade. Esophageal achalasia, a less common disorder in the pediatric patient population, is characterized by dysphagia and treated with pneumatic balloon dilation and/or esophagomyotomy. Gastroparesis and chronic intestinal pseudo-obstruction are poorly characterized in children and are associated with significant morbidity. Constipation is among the most common complaints in children and is associated with significant morbidity as well as poor quality of life. Data on epidemiology and outcomes, clinical trials, and evaluation of new diagnostic techniques are needed to better diagnose and treat gastrointestinal motility disorders in children. We present a review of the conditions and challenges related to these common gastrointestinal motility disorders in children. PMID:24799835

  14. Complaints against Nursing Homes: Comparing Two Sources of Complaint Information and Predictors of Complaints

    ERIC Educational Resources Information Center

    Troyer, Jennifer L.; Sause, Wendy L.

    2011-01-01

    Purpose of the Study: Two consumer-derived measures of nursing home quality that have been underutilized by researchers are consumer complaints to the state certification agency between inspections and complaints to the Long-Term Care Ombudsman Program. This article describes these complaints, considers facility-level predictors of complaints, and…

  15. Flexible Gastrointestinal Endoscopy in Ferrets (Mustela putorius furo).

    PubMed

    Pignon, Charly; Huynh, Minh; Husnik, Roman; Jekl, Vladimir

    2015-09-01

    Gastrointestinal disease is a common complaint in ferrets (Mustela putorius furo). Their relatively simple and short gastrointestinal tract makes them good candidates for flexible endoscopy. However, apart from a few references in biomedical research articles, there is little information on the use of flexible endoscopy in ferrets. This review describes patient preparation, equipment, and select gastrointestinal endoscopy techniques in ferrets, including esophagoscopy, gastroscopy, duodenoscopy, percutaneous endoscopic gastrostomy, jejunoileoscopy, colonoscopy, and biopsy.

  16. 9. Painful shoulder complaints.

    PubMed

    Huygen, Frank; Patijn, Jacob; Rohof, Olav; Lataster, Arno; Mekhail, Nagy; van Kleef, Maarten; Van Zundert, Jan

    2010-01-01

    Painful shoulder complaints have a high incidence and prevalence. The etiology is not always clear. Clinical history and the active and passive motion examination of the shoulder are the cornerstones of the diagnostic process. Three shoulder tests are important for the examination of shoulder complaints: shoulder abduction, shoulder external rotation, and horizontal shoulder adduction. These tests can guide the examiner to the correct diagnosis. Based on this diagnosis, in most cases, primarily a conservative treatment with nonsteroidal anti-inflammatory drugs possibly in combination with manual and/or exercise therapy can be started. When conservative treatment fails, injection with local anesthetics and corticosteroids can be considered. In the case of frozen shoulder, a continuous cervical epidural infusion of local anesthetic and small doses of opioids or a pulsed radiofrequency treatment of the nervus suprascapularis can be considered.

  17. Gastrointestinal Infections.

    PubMed

    Alby, Kevin; Nachamkin, Irving

    2016-06-01

    Gastrointestinal infections in the immunocompromised host are caused by the common bacterial, viral, fungal, and parasitic agents that also cause infections in the immunocompetent host. Of special consideration is that immunocompromised patients may be at increased risk for infection or disease severity and by pathogens not seen in the competent host. This chapter reviews the various agents, risk factors, and diagnostic approaches to detect gastrointestinal infections in this patient population. PMID:27337464

  18. 37 CFR 4.3 - Submitting complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... COMMERCE GENERAL COMPLAINTS REGARDING INVENTION PROMOTERS § 4.3 Submitting complaints. (a) A person may submit a complaint concerning an invention promoter with the Office. A person submitting a complaint should understand that the complaint may be forwarded to the invention promoter and may become...

  19. 37 CFR 4.3 - Submitting complaints.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... COMMERCE GENERAL COMPLAINTS REGARDING INVENTION PROMOTERS § 4.3 Submitting complaints. (a) A person may submit a complaint concerning an invention promoter with the Office. A person submitting a complaint should understand that the complaint may be forwarded to the invention promoter and may become...

  20. 48 CFR 422.1308 - Complaint procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Vietnam Era, and Other Eligible Veterans 422.1308 Complaint procedures. The contracting officer shall forward complaints received about the administration of the Vietnam Era Veterans Readjustment...

  1. 48 CFR 422.1308 - Complaint procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Vietnam Era, and Other Eligible Veterans 422.1308 Complaint procedures. The contracting officer shall forward complaints received about the administration of the Vietnam Era Veterans Readjustment...

  2. 48 CFR 422.1308 - Complaint procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Vietnam Era, and Other Eligible Veterans 422.1308 Complaint procedures. The contracting officer shall forward complaints received about the administration of the Vietnam Era Veterans Readjustment...

  3. 48 CFR 422.1308 - Complaint procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Vietnam Era, and Other Eligible Veterans 422.1308 Complaint procedures. The contracting officer shall forward complaints received about the administration of the Vietnam Era Veterans Readjustment...

  4. 39 CFR 3030.10 - Complaint contents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Complaint contents. 3030.10 Section 3030.10 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES FOR COMPLAINTS Form and Manner Requirements of Initial Pleadings § 3030.10 Complaint contents. (a) A complaint must: (1) Set forth the facts...

  5. 39 CFR 3030.10 - Complaint contents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Complaint contents. 3030.10 Section 3030.10 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES FOR COMPLAINTS Form and Manner Requirements of Initial Pleadings § 3030.10 Complaint contents. (a) A complaint must: (1) Set forth the facts...

  6. 39 CFR 3030.10 - Complaint contents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Complaint contents. 3030.10 Section 3030.10 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES FOR COMPLAINTS Form and Manner Requirements of Initial Pleadings § 3030.10 Complaint contents. (a) A complaint must: (1) Set forth the facts...

  7. 21 CFR 1271.320 - Complaint file.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Complaint file. 1271.320 Section 1271.320 Food and... CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.320 Complaint file. (a) Procedures... the investigation of complaints as appropriate. (b) Complaint file. You must maintain a record...

  8. 39 CFR 3030.10 - Complaint contents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Complaint contents. 3030.10 Section 3030.10 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES FOR COMPLAINTS Form and Manner Requirements of Initial Pleadings § 3030.10 Complaint contents. (a) A complaint must: (1) Set forth the facts...

  9. 37 CFR 4.3 - Submitting complaints.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Submitting complaints. 4.3... COMMERCE GENERAL COMPLAINTS REGARDING INVENTION PROMOTERS § 4.3 Submitting complaints. (a) A person may submit a complaint concerning an invention promoter with the Office. A person submitting a...

  10. 37 CFR 4.3 - Submitting complaints.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Submitting complaints. 4.3... COMMERCE GENERAL COMPLAINTS REGARDING INVENTION PROMOTERS § 4.3 Submitting complaints. (a) A person may submit a complaint concerning an invention promoter with the Office. A person submitting a...

  11. 37 CFR 4.3 - Submitting complaints.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Submitting complaints. 4.3... COMMERCE GENERAL COMPLAINTS REGARDING INVENTION PROMOTERS § 4.3 Submitting complaints. (a) A person may submit a complaint concerning an invention promoter with the Office. A person submitting a...

  12. 39 CFR 3030.10 - Complaint contents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Complaint contents. 3030.10 Section 3030.10 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES FOR COMPLAINTS Form and Manner Requirements of Initial Pleadings § 3030.10 Complaint contents. (a) A complaint must: (1) Set forth the facts...

  13. A man with worsening gastrointestinal and neurologic symptoms.

    PubMed

    Irving, David

    2016-08-01

    A Coast Guardsman deployed to a remote island in the Bahamas contacted his primary care office about worsening gastrointestinal and neurologic complaints. This article describes the telemedicine consultation to determine the cause of his symptoms, whether he needed emergency evacuation, and how treatment was handled. PMID:27467293

  14. A man with worsening gastrointestinal and neurologic symptoms.

    PubMed

    Irving, David

    2016-08-01

    A Coast Guardsman deployed to a remote island in the Bahamas contacted his primary care office about worsening gastrointestinal and neurologic complaints. This article describes the telemedicine consultation to determine the cause of his symptoms, whether he needed emergency evacuation, and how treatment was handled.

  15. Gastrointestinal manifestations in myotonic muscular dystrophy

    PubMed Central

    Bellini, Massimo; Biagi, Sonia; Stasi, Cristina; Costa, Francesco; Mumolo, Maria Gloria; Ricchiuti, Angelo; Marchi, Santino

    2006-01-01

    Myotonic dystrophy (MD) is characterized by myotonic phenomena and progressive muscular weakness. Involvement of the gastrointestinal tract is frequent and may occur at any level. The clinical manifestations have previously been attributed to motility disorders caused by smooth muscle damage, but histologic evidence of alterations has been scarce and conflicting. A neural factor has also been hypothesized. In the upper digestive tract, dysphagia, heartburn, regurgitation and dyspepsia are the most common complaints, while in the lower tract, abdominal pain, bloating and changes in bowel habits are often reported. Digestive symptoms may be the first sign of dystrophic disease and may precede the musculo-skeletal features. The impairment of gastrointestinal function may be sometimes so gradual that the patients adapt to it with little awareness of symptoms. In such cases routine endoscopic and ultrasonographic evaluations are not sufficient and targeted techniques (electrogastrography, manometry, electromyography, functional ultrasonography, scintigraphy, etc.) are needed. There is a low correlation between the degree of skeletal muscle involvement and the presence and severity of gastrointestinal disturbances whereas a positive correlation with the duration of the skeletal muscle disease has been reported. The drugs recommended for treating the gastrointestinal complaints such as prokinetic, anti-dyspeptic drugs and laxatives, are mainly aimed at correcting the motility disorders. Gastrointestinal involvement in MD remains a complex and intriguing condition since many important problems are still unsolved. Further studies concentrating on genetic aspects, early diagnostic techniques and the development of new therapeutic strategies are needed to improve our management of the gastrointestinal manifestations of MD. PMID:16609987

  16. Customer complaints in the National Health Service.

    PubMed

    Reid, N; Reid, R; Morris, D

    1995-11-01

    This paper addresses the role of consumer complaints in the flourishing quality assurance industry within the National Health Service (NHS), and considers the traditional ethos of complaints within the service. The advent of the internal market is considered as one of a range of factors which may change attitudes of NHS staff to complaints. In evaluating how complaints services might develop relevant literature is reviewed and recent national data on complaints procedures are cited. PMID:8548145

  17. Associations between long commutes and subjective health complaints among railway workers in Norway.

    PubMed

    Urhonen, Terhi; Lie, Arve; Aamodt, Geir

    2016-12-01

    Commuting is an important aspect of daily life for many employees, but there is little knowledge of how this affects individual commuters' health and well-being. The authors investigated the relationship between commuting and subjective health complaints, using data from a web-based questionnaire. In a sample of 2126 railway employees, 644 (30.3%) had long commute times. A 29-item inventory was used to measure the number and degree of the subjective health complaints. Those who commuted 60 min or more each way were characterized by significantly higher numbers and degrees of subjective health complaints compared with their peers with short commutes. The mean number of complaints was 7.5 among the former group and 6.4 for the latter group (p = 0.009). In a regression model, in which the authors controlled for age, gender, education, self-rated health, and coping, the employees with long commutes reported more complaints than those with short commutes. Significant associations were found between those with long commutes and the number and degree of incidences of self-reported musculoskeletal pain, pseudo-neurologic complaints, and gastrointestinal problems. Commuters who had had long commutes for more than 10 years reported more gastrointestinal and musculoskeletal complaints than those with long commutes for less than 2 years. Also, commuters with long commutes spent less time with their families and leisure activities compared with those with short commutes. The authors conclude that the association between long commute times and higher levels of subjective health complaints should attract the attention of transport planners, employers, and public health policymaker.

  18. Associations between long commutes and subjective health complaints among railway workers in Norway.

    PubMed

    Urhonen, Terhi; Lie, Arve; Aamodt, Geir

    2016-12-01

    Commuting is an important aspect of daily life for many employees, but there is little knowledge of how this affects individual commuters' health and well-being. The authors investigated the relationship between commuting and subjective health complaints, using data from a web-based questionnaire. In a sample of 2126 railway employees, 644 (30.3%) had long commute times. A 29-item inventory was used to measure the number and degree of the subjective health complaints. Those who commuted 60 min or more each way were characterized by significantly higher numbers and degrees of subjective health complaints compared with their peers with short commutes. The mean number of complaints was 7.5 among the former group and 6.4 for the latter group (p = 0.009). In a regression model, in which the authors controlled for age, gender, education, self-rated health, and coping, the employees with long commutes reported more complaints than those with short commutes. Significant associations were found between those with long commutes and the number and degree of incidences of self-reported musculoskeletal pain, pseudo-neurologic complaints, and gastrointestinal problems. Commuters who had had long commutes for more than 10 years reported more gastrointestinal and musculoskeletal complaints than those with long commutes for less than 2 years. Also, commuters with long commutes spent less time with their families and leisure activities compared with those with short commutes. The authors conclude that the association between long commute times and higher levels of subjective health complaints should attract the attention of transport planners, employers, and public health policymaker. PMID:27660744

  19. Gastrointestinal system

    PubMed Central

    Cheng, Leo K.; O’Grady, Gregory; Du, Peng; Egbuji, John U.; Windsor, John A.; Pullan, Andrew J.

    2014-01-01

    The functions of the gastrointestinal (GI) tract include digestion, absorption, excretion, and protection. In this review, we focus on the electrical activity of the stomach and small intestine, which underlies the motility of these organs, and where the most detailed systems descriptions and computational models have been based to date. Much of this discussion is also applicable to the rest of the GI tract. This review covers four major spatial scales: cell, tissue, organ, and torso, and discusses the methods of investigation and the challenges associated with each. We begin by describing the origin of the electrical activity in the interstitial cells of Cajal, and its spread to smooth muscle cells. The spread of electrical activity through the stomach and small intestine is then described, followed by the resultant electrical and magnetic activity that may be recorded on the body surface. A number of common and highly symptomatic GI conditions involve abnormal electrical and/or motor activity, which are often termed functional disorders. In the last section of this review we address approaches being used to characterize and diagnose abnormalities in the electrical activity and how these might be applied in the clinical setting. The understanding of electrophysiology and motility of the GI system remains a challenging field, and the review discusses how biophysically based mathematical models can help to bridge gaps in our current knowledge, through integration of otherwise separate concepts. PMID:20836011

  20. Reproducible research in palaeomagnetism

    NASA Astrophysics Data System (ADS)

    Lurcock, Pontus; Florindo, Fabio

    2015-04-01

    The reproducibility of research findings is attracting increasing attention across all scientific disciplines. In palaeomagnetism as elsewhere, computer-based analysis techniques are becoming more commonplace, complex, and diverse. Analyses can often be difficult to reproduce from scratch, both for the original researchers and for others seeking to build on the work. We present a palaeomagnetic plotting and analysis program designed to make reproducibility easier. Part of the problem is the divide between interactive and scripted (batch) analysis programs. An interactive desktop program with a graphical interface is a powerful tool for exploring data and iteratively refining analyses, but usually cannot operate without human interaction. This makes it impossible to re-run an analysis automatically, or to integrate it into a larger automated scientific workflow - for example, a script to generate figures and tables for a paper. In some cases the parameters of the analysis process itself are not saved explicitly, making it hard to repeat or improve the analysis even with human interaction. Conversely, non-interactive batch tools can be controlled by pre-written scripts and configuration files, allowing an analysis to be 'replayed' automatically from the raw data. However, this advantage comes at the expense of exploratory capability: iteratively improving an analysis entails a time-consuming cycle of editing scripts, running them, and viewing the output. Batch tools also tend to require more computer expertise from their users. PuffinPlot is a palaeomagnetic plotting and analysis program which aims to bridge this gap. First released in 2012, it offers both an interactive, user-friendly desktop interface and a batch scripting interface, both making use of the same core library of palaeomagnetic functions. We present new improvements to the program that help to integrate the interactive and batch approaches, allowing an analysis to be interactively explored and refined

  1. Magnetogastrography (MGG) Reproducibility Assessments

    NASA Astrophysics Data System (ADS)

    de la Roca-Chiapas, J. M.; Córdova, T.; Hernández, E.; Solorio, S.; Solís Ortiz, S.; Sosa, M.

    2006-09-01

    Seven healthy subjects underwent a magnetic pulse of 32 mT for 17 ms, seven times in 90 minutes. The procedure was repeated one and two weeks later. Assessments of the gastric emptying were carried out for each one of the measurements and a statistical analysis of ANOVA was performed for every group of data. The gastric emptying time was 19.22 ± 5 min. Reproducibility estimation was above 85%. Therefore, magnetogastrography seems to be an excellent technique to be implemented in routine clinical trials.

  2. Opening Reproducible Research

    NASA Astrophysics Data System (ADS)

    Nüst, Daniel; Konkol, Markus; Pebesma, Edzer; Kray, Christian; Klötgen, Stephanie; Schutzeichel, Marc; Lorenz, Jörg; Przibytzin, Holger; Kussmann, Dirk

    2016-04-01

    Open access is not only a form of publishing such that research papers become available to the large public free of charge, it also refers to a trend in science that the act of doing research becomes more open and transparent. When science transforms to open access we not only mean access to papers, research data being collected, or data being generated, but also access to the data used and the procedures carried out in the research paper. Increasingly, scientific results are generated by numerical manipulation of data that were already collected, and may involve simulation experiments that are completely carried out computationally. Reproducibility of research findings, the ability to repeat experimental procedures and confirm previously found results, is at the heart of the scientific method (Pebesma, Nüst and Bivand, 2012). As opposed to the collection of experimental data in labs or nature, computational experiments lend themselves very well for reproduction. Some of the reasons why scientists do not publish data and computational procedures that allow reproduction will be hard to change, e.g. privacy concerns in the data, fear for embarrassment or of losing a competitive advantage. Others reasons however involve technical aspects, and include the lack of standard procedures to publish such information and the lack of benefits after publishing them. We aim to resolve these two technical aspects. We propose a system that supports the evolution of scientific publications from static papers into dynamic, executable research documents. The DFG-funded experimental project Opening Reproducible Research (ORR) aims for the main aspects of open access, by improving the exchange of, by facilitating productive access to, and by simplifying reuse of research results that are published over the Internet. Central to the project is a new form for creating and providing research results, the executable research compendium (ERC), which not only enables third parties to

  3. Reproducing in cities.

    PubMed

    Mace, Ruth

    2008-02-01

    Reproducing in cities has always been costly, leading to lower fertility (that is, lower birth rates) in urban than in rural areas. Historically, although cities provided job opportunities, initially residents incurred the penalty of higher infant mortality, but as mortality rates fell at the end of the 19th century, European birth rates began to plummet. Fertility decline in Africa only started recently and has been dramatic in some cities. Here it is argued that both historical and evolutionary demographers are interpreting fertility declines across the globe in terms of the relative costs of child rearing, which increase to allow children to outcompete their peers. Now largely free from the fear of early death, postindustrial societies may create an environment that generates runaway parental investment, which will continue to drive fertility ever lower.

  4. 20 CFR 658.412 - Complaint resolution.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Complaint resolution. 658.412 Section 658.412 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR ADMINISTRATIVE PROVISIONS... Complaint resolution. (a) A JS-related complaint is resolved when: (1) The complainant...

  5. 45 CFR 617.9 - Complaints.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION NONDISCRIMINATION ON THE BASIS... complaint, any written statement which identifies the parties involved and the date the complainant first... the amended complaint was filed. (c) On receipt of any complaint NSF shall promptly send...

  6. 45 CFR 617.9 - Complaints.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION NONDISCRIMINATION ON THE BASIS... complaint, any written statement which identifies the parties involved and the date the complainant first... the amended complaint was filed. (c) On receipt of any complaint NSF shall promptly send...

  7. 47 CFR 8.12 - Formal complaints.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Formal complaints. 8.12 Section 8.12 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.12 Formal complaints. Any person may file a formal complaint alleging a violation of the rules in this part....

  8. 47 CFR 8.12 - Formal complaints.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Formal complaints. 8.12 Section 8.12 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.12 Formal complaints. Any person may file a formal complaint alleging a violation of the rules in this part....

  9. 47 CFR 8.12 - Formal Complaints.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Formal Complaints. 8.12 Section 8.12 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.12 Formal Complaints. Any person may file a formal complaint alleging a violation of the rules in this part....

  10. 47 CFR 8.12 - Formal complaints.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Formal complaints. 8.12 Section 8.12 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.12 Formal complaints. Any person may file a formal complaint alleging a violation of the rules in this part....

  11. 10 CFR 13.7 - Complaint.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Complaint. 13.7 Section 13.7 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.7 Complaint. (a) On or after the date the Department of Justice approves the issuance of a complaint in accordance with 31 U.S.C. 3803(b)(1), the reviewing official...

  12. 12 CFR 528.8 - Complaints.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Complaints. 528.8 Section 528.8 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY NONDISCRIMINATION REQUIREMENTS § 528.8 Complaints. Complaints regarding discrimination in lending by a savings association shall be referred to the Assistant Secretary for Fair Housing...

  13. 48 CFR 408.711 - Quality complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Quality complaints. 408... People Who Are Blind or Severely Disabled 408.711 Quality complaints. Prior to attempting to resolve a complaint regarding the quality of goods or services provided by participating nonprofit agency with...

  14. 48 CFR 408.711 - Quality complaints.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Quality complaints. 408... People Who Are Blind or Severely Disabled 408.711 Quality complaints. Prior to attempting to resolve a complaint regarding the quality of goods or services provided by participating nonprofit agency with...

  15. 47 CFR 1.1404 - Complaint.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Pole Attachment Complaint... for pole attachments. The complaint shall include a statement that the utility is not owned by any... State. (d) The complaint shall be accompanied by a copy of the pole attachment agreement, if...

  16. 21 CFR 211.198 - Complaint files.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Complaint files. 211.198 Section 211.198 Food and... files. (a) Written procedures describing the handling of all written and oral complaints regarding a...) A written record of each complaint shall be maintained in a file designated for drug...

  17. 21 CFR 820.198 - Complaint files.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Complaint files. 820.198 Section 820.198 Food and... QUALITY SYSTEM REGULATION Records § 820.198 Complaint files. (a) Each manufacturer shall maintain complaint files. Each manufacturer shall establish and maintain procedures for receiving, reviewing,...

  18. 6 CFR 13.7 - Complaint.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Complaint. 13.7 Section 13.7 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.7 Complaint. (a) On or after the date the Department of Justice approves the issuance of a Complaint in...

  19. 6 CFR 13.7 - Complaint.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Complaint. 13.7 Section 13.7 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.7 Complaint. (a) On or after the date the Department of Justice approves the issuance of a Complaint in...

  20. 7 CFR 1.163 - The complaint.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false The complaint. 1.163 Section 1.163 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Rules of Practice Governing Cease and Desist Proceedings Under Section 2 of the Capper-Volstead Act § 1.163 The complaint. The complaint...

  1. 7 CFR 1.163 - The complaint.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false The complaint. 1.163 Section 1.163 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Rules of Practice Governing Cease and Desist Proceedings Under Section 2 of the Capper-Volstead Act § 1.163 The complaint. The complaint...

  2. 7 CFR 1.163 - The complaint.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 1 2014-01-01 2014-01-01 false The complaint. 1.163 Section 1.163 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Rules of Practice Governing Cease and Desist Proceedings Under Section 2 of the Capper-Volstead Act § 1.163 The complaint. The complaint...

  3. 7 CFR 1.163 - The complaint.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false The complaint. 1.163 Section 1.163 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Rules of Practice Governing Cease and Desist Proceedings Under Section 2 of the Capper-Volstead Act § 1.163 The complaint. The complaint...

  4. 41 CFR 50-205.6 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Complaints. 50-205.6 Section 50-205.6 Public Contracts and Property Management Other Provisions Relating to Public Contracts... AND EMPLOYEES § 50-205.6 Complaints. When a complaint of alleged safety and health violations by...

  5. 14 CFR 302.404 - Formal complaints.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... business or the ends of justice. (e) Service. A formal complaint, and any amendments thereto, shall be... does so under § 302.406(c). (b) Amendment. A formal complaint may be amended at any time before service of an answer to the complaint. After service of an answer but before institution of an...

  6. 14 CFR 302.404 - Formal complaints.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... business or the ends of justice. (e) Service. A formal complaint, and any amendments thereto, shall be... does so under § 302.406(c). (b) Amendment. A formal complaint may be amended at any time before service of an answer to the complaint. After service of an answer but before institution of an...

  7. 14 CFR 302.404 - Formal complaints.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... business or the ends of justice. (e) Service. A formal complaint, and any amendments thereto, shall be... does so under § 302.406(c). (b) Amendment. A formal complaint may be amended at any time before service of an answer to the complaint. After service of an answer but before institution of an...

  8. 14 CFR 302.404 - Formal complaints.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... business or the ends of justice. (e) Service. A formal complaint, and any amendments thereto, shall be... does so under § 302.406(c). (b) Amendment. A formal complaint may be amended at any time before service of an answer to the complaint. After service of an answer but before institution of an...

  9. 14 CFR 302.404 - Formal complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... business or the ends of justice. (e) Service. A formal complaint, and any amendments thereto, shall be... does so under § 302.406(c). (b) Amendment. A formal complaint may be amended at any time before service of an answer to the complaint. After service of an answer but before institution of an...

  10. 46 CFR 502.64 - Answer to complaint; counter-complaint.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 9 2011-10-01 2011-10-01 false Answer to complaint; counter-complaint. 502.64 Section 502.64 Shipping FEDERAL MARITIME COMMISSION GENERAL AND ADMINISTRATIVE PROVISIONS RULES OF PRACTICE AND PROCEDURE Proceedings; Pleadings; Motions; Replies § 502.64 Answer to complaint; counter-complaint. (a) Respondent shall file with the...

  11. Public Complaints and Complaint Responses in Calls to a Jordanian Radio Phone-In Program

    ERIC Educational Resources Information Center

    Migdadi, Fathi; Badarneh, Muhammad A.; Momani, Kawakib

    2012-01-01

    This study investigates complaints and complaint responses in interactions between local citizens and the hosts of a live two-hour radio phone-in in Jordan devoted to receiving and handling complaints of a public nature. Using Brown and Levinson's (1987) politeness model, the study examines the functions and patterns of complaints and the types of…

  12. Gastrointestinal Symptoms among African Americans Undergoing Hemodialysis.

    PubMed

    Daniels, Glenda; Robinson, Janie R; Walker, Charles; Pennings, Jacquelyn S; Anderson, Staci T

    2015-01-01

    The incidence of end stage renal disease is more than three times higher in African Americans. Treatment regimens contribute to gastrointestinal (GI) complaints. This study's purpose was to examine the incidence of GI symptoms in African-American patients undergoing hemodialysis. Younger participants were more likely to report mild indigestion, while older participants reported severe indigestion or none at all. Females were more likely to report gastrointestinal symptoms. Commonly reported co-morbidities included hypertension, diabetes, and heart disease. Time on hemodialysis ranged from 1 to 279 months. Those who had been on hemodialysis the longest were more likely to report acid reflux, stomach rumbling and mild diarrhea. This study provides a foundation for early identification of GI symptoms in African-Americans patients undergoing hemodialysis.

  13. Somatic complaints in childhood tic disorders.

    PubMed

    Frank, M S; Sieg, K G; Gaffney, G R

    1991-01-01

    Twenty-six children diagnosed with chronic tic disorders (18 with Gilles de la Tourette syndrome and 8 with chronic motor tic disorder) were studied for unexplained physical complaints. Compared to normal controls, an excess of somatic complaints was found in the tic disorders group; this was similar to an excess of somatic complaints in a mixed psychiatric clinic group. Medication produced no significant effect on somatic complaints for patients in the tic and psychiatric clinic groups. Within the tic disorders group, no significant correlation was found between the increased somatic complaints and the severity of anxiety, dysphoria, or movement disorder. PMID:1961851

  14. Reproducible Experiment Platform

    NASA Astrophysics Data System (ADS)

    Likhomanenko, Tatiana; Rogozhnikov, Alex; Baranov, Alexander; Khairullin, Egor; Ustyuzhanin, Andrey

    2015-12-01

    Data analysis in fundamental sciences nowadays is an essential process that pushes frontiers of our knowledge and leads to new discoveries. At the same time we can see that complexity of those analyses increases fast due to a) enormous volumes of datasets being analyzed, b) variety of techniques and algorithms one have to check inside a single analysis, c) distributed nature of research teams that requires special communication media for knowledge and information exchange between individual researchers. There is a lot of resemblance between techniques and problems arising in the areas of industrial information retrieval and particle physics. To address those problems we propose Reproducible Experiment Platform (REP), a software infrastructure to support collaborative ecosystem for computational science. It is a Python based solution for research teams that allows running computational experiments on shared datasets, obtaining repeatable results, and consistent comparisons of the obtained results. We present some key features of REP based on case studies which include trigger optimization and physics analysis studies at the LHCb experiment.

  15. Zinc and gastrointestinal disease

    PubMed Central

    Skrovanek, Sonja; DiGuilio, Katherine; Bailey, Robert; Huntington, William; Urbas, Ryan; Mayilvaganan, Barani; Mercogliano, Giancarlo; Mullin, James M

    2014-01-01

    This review is a current summary of the role that both zinc deficiency and zinc supplementation can play in the etiology and therapy of a wide range of gastrointestinal diseases. The recent literature describing zinc action on gastrointestinal epithelial tight junctions and epithelial barrier function is described. Zinc enhancement of gastrointestinal epithelial barrier function may figure prominently in its potential therapeutic action in several gastrointestinal diseases. PMID:25400994

  16. The network organisation of consumer complaints

    NASA Astrophysics Data System (ADS)

    Rocha, L. E. C.; Holme, P.

    2010-07-01

    Interaction between consumers and companies can create conflict. When a consensus is unreachable there are legal authorities to resolve the case. This letter is a study of data from the Brazilian Department of Justice from which we build a bipartite network of categories of complaints linked to the companies receiving those complaints. We find the complaint categories organised in an hierarchical way where companies only get complaints of lower degree if they already got complaints of higher degree. The fraction of resolved complaints for a company appears to be nearly independent of the equity of the company but is positively correlated with the total number of complaints received. We construct feature vectors based on the edge-weight —the weight of an edge represents the times complaints of a category have been filed against that company— and use these vectors to study the similarity between the categories of complaints. From this analysis, we obtain trees mapping the hierarchical organisation of the complaints. We also apply principal component analysis to the set of feature vectors concluding that a reduction of the dimensionality of these from 8827 to 27 gives an optimal hierarchical representation.

  17. Reproducibility in a multiprocessor system

    DOEpatents

    Bellofatto, Ralph A; Chen, Dong; Coteus, Paul W; Eisley, Noel A; Gara, Alan; Gooding, Thomas M; Haring, Rudolf A; Heidelberger, Philip; Kopcsay, Gerard V; Liebsch, Thomas A; Ohmacht, Martin; Reed, Don D; Senger, Robert M; Steinmacher-Burow, Burkhard; Sugawara, Yutaka

    2013-11-26

    Fixing a problem is usually greatly aided if the problem is reproducible. To ensure reproducibility of a multiprocessor system, the following aspects are proposed; a deterministic system start state, a single system clock, phase alignment of clocks in the system, system-wide synchronization events, reproducible execution of system components, deterministic chip interfaces, zero-impact communication with the system, precise stop of the system and a scan of the system state.

  18. Sleep complaints and fatigue of airline pilots.

    PubMed

    Reis, Cátia; Mestre, Catarina; Canhão, Helena; Gradwell, David; Paiva, Teresa

    2016-01-01

    This work aimed to determine daytime sleepiness and sleep complaints prevalence and the corresponding influence on perceived fatigue and to evaluate the influence of sociodemographic parameters and labour variables on sleep complaints, sleepiness and fatigue. A questionnaire was developed including socio-economic and labour issues and instruments, focused in sleep and fatigue. The response rate was 32% and the final sample had 435 pilots. The prevalence of sleep complaints was 34.9%, daytime sleepiness 59.3% and fatigue 90.6%. The high prevalence of sleep complaints, sleepiness and fatigue was disclosed in pilots, with those who fly short/medium having an added risk of fatigue. PMID:27656269

  19. Sleep complaints and fatigue of airline pilots.

    PubMed

    Reis, Cátia; Mestre, Catarina; Canhão, Helena; Gradwell, David; Paiva, Teresa

    2016-01-01

    This work aimed to determine daytime sleepiness and sleep complaints prevalence and the corresponding influence on perceived fatigue and to evaluate the influence of sociodemographic parameters and labour variables on sleep complaints, sleepiness and fatigue. A questionnaire was developed including socio-economic and labour issues and instruments, focused in sleep and fatigue. The response rate was 32% and the final sample had 435 pilots. The prevalence of sleep complaints was 34.9%, daytime sleepiness 59.3% and fatigue 90.6%. The high prevalence of sleep complaints, sleepiness and fatigue was disclosed in pilots, with those who fly short/medium having an added risk of fatigue.

  20. 47 CFR 76.954 - Initial review of complaint; minimum showing requirement; dismissal of defective complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Cable Rate... the complaint is filed using the standard complaint form described in § 76.951 and includes...

  1. Gastrointestinal Morbidity in Obesity

    PubMed Central

    Acosta, Andres; Camilleri, Michael

    2014-01-01

    Obesity is a complex disease that results from increased energy intake and decreased energy expenditure. The gastrointestinal system plays a key role in the pathogenesis of obesity and facilitates caloric imbalance. Changes in gastrointestinal hormones and the inhibition of mechanisms that curtail caloric intake result in weight gain. It is not clear if the gastrointestinal role in obesity is a cause or an effect of this disease. Obesity is often associated with type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD). Obesity is also associated with gastrointestinal disorders, which are more frequent and present earlier than T2DM and CVD. Diseases such as gastro-esophageal reflux disease, cholelithiasis or non-alcoholic steatohepatitis are directly related to body weight and abdominal adiposity. Our objective is to assess the role of each gastrointestinal organ in obesity and the gastrointestinal morbidity resulting in those organs from effects of obesity. PMID:24602085

  2. Gastrointestinal disorders - resources

    MedlinePlus

    Digestive disease - resources; Resources - gastrointestinal disorders ... org American Liver Foundation -- www.liverfoundation.org National Digestive Diseases Information Clearinghouse -- digestive.niddk.nih.gov

  3. 10 CFR 4.332 - Complaints.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Complaints. 4.332 Section 4.332 Energy NUCLEAR REGULATORY... member of a class or on behalf of others, may file a complaint with NRC, alleging discrimination prohibited by the Act or these regulations based on an action occurring on or after July 1, 1979....

  4. 10 CFR 4.332 - Complaints.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Complaints. 4.332 Section 4.332 Energy NUCLEAR REGULATORY... member of a class or on behalf of others, may file a complaint with NRC, alleging discrimination prohibited by the Act or these regulations based on an action occurring on or after July 1, 1979....

  5. 15 CFR 8.8 - Complaints.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... and Foreign Trade Office of the Secretary of Commerce NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OF THE DEPARTMENT OF COMMERCE-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 General Compliance § 8.8 Complaints. (a) Filing complaints. Any person who believes himself or any specific class...

  6. 7 CFR 15.6 - Complaints.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Department of Agriculture-Effectuation of Title VI of the Civil Rights Act of 1964 § 15.6 Complaints. Any... for Civil Rights. The complaint shall be investigated in the manner determined by the Assistant Secretary for Civil Rights and such further action taken by the Agency or the Secretary as may be......

  7. 44 CFR 7.941 - Complaints.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Complaints. 7.941 Section 7.941 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND... file a complaint within 180 days from the date the complainant first had knowledge of the alleged...

  8. 47 CFR 76.1713 - Complaint resolution.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Complaint resolution. 76.1713 Section 76.1713 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Documents to be Maintained for Inspection § 76.1713 Complaint resolution....

  9. 30 CFR 270.5 - Complaint.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Complaint. 270.5 Section 270.5 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE NONDISCRIMINATION IN THE OUTER CONTINENTAL SHELF § 270.5 Complaint. (a) Whenever any person believes that he or...

  10. 30 CFR 270.5 - Complaint.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Complaint. 270.5 Section 270.5 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE NONDISCRIMINATION IN THE OUTER CONTINENTAL SHELF § 270.5 Complaint. (a) Whenever any person believes that he or...

  11. 30 CFR 270.5 - Complaint.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Complaint. 270.5 Section 270.5 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE NONDISCRIMINATION IN THE OUTER CONTINENTAL SHELF § 270.5 Complaint. (a) Whenever any person believes that he or...

  12. 44 CFR 7.941 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... file a complaint within 180 days from the date the complainant first had knowledge of the alleged act... written statement which identifies the parties involved and the date the complainant first had knowledge... requirements of a sufficient complaint. (3) Notifying the complainant and the recipient of their rights...

  13. 10 CFR 1040.89-5 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Rights and Diversity, may extend the time limit for filing a complaint. Complaints may be submitted to... and Diversity, Forrestal Building, 1000 Independence Avenue, SW., Washington, D.C. 20585. (b) The Director, Office of Civil Rights and Diversity, will attempt to facilitate the filing of...

  14. 10 CFR 1040.89-5 - Complaints.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Rights and Diversity, may extend the time limit for filing a complaint. Complaints may be submitted to... and Diversity, Forrestal Building, 1000 Independence Avenue, SW., Washington, D.C. 20585. (b) The Director, Office of Civil Rights and Diversity, will attempt to facilitate the filing of...

  15. 10 CFR 1040.89-5 - Complaints.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Rights and Diversity, may extend the time limit for filing a complaint. Complaints may be submitted to... and Diversity, Forrestal Building, 1000 Independence Avenue, SW., Washington, D.C. 20585. (b) The Director, Office of Civil Rights and Diversity, will attempt to facilitate the filing of...

  16. 10 CFR 1040.89-5 - Complaints.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Rights and Diversity, may extend the time limit for filing a complaint. Complaints may be submitted to... and Diversity, Forrestal Building, 1000 Independence Avenue, SW., Washington, D.C. 20585. (b) The Director, Office of Civil Rights and Diversity, will attempt to facilitate the filing of...

  17. 10 CFR 1040.89-5 - Complaints.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Rights and Diversity, may extend the time limit for filing a complaint. Complaints may be submitted to... and Diversity, Forrestal Building, 1000 Independence Avenue, SW., Washington, D.C. 20585. (b) The Director, Office of Civil Rights and Diversity, will attempt to facilitate the filing of...

  18. 40 CFR 7.120 - Complaint investigations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... recipients of Federal assistance (see 28 CFR part 42, subpart H and 29 CFR part 1691). Complaints of... with the Equal Employment Opportunity Commission (see 29 CFR part 1626). Complainants are encouraged... Compliance Procedures § 7.120 Complaint investigations. The OCR shall promptly investigate all...

  19. 45 CFR 98.93 - Complaints.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Complaints. 98.93 Section 98.93 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Monitoring... for Children and Families, 370 L'Enfant Promenade, SW., Washington, DC 20447. The complaint...

  20. 45 CFR 98.93 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Complaints. 98.93 Section 98.93 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Monitoring... for Children and Families, 370 L'Enfant Promenade, SW., Washington, DC 20447. The complaint...

  1. 48 CFR 8.711 - Quality complaints.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Quality complaints. 8.711... Blind or Severely Disabled 8.711 Quality complaints. (a) When the quality of supplies or services... the appropriate central nonprofit agency. (b) When quality problems cannot be resolved by the...

  2. 48 CFR 8.711 - Quality complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Quality complaints. 8.711... Blind or Severely Disabled 8.711 Quality complaints. (a) When the quality of supplies or services... the appropriate central nonprofit agency. (b) When quality problems cannot be resolved by the...

  3. 30 CFR 570.5 - Complaint.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Complaint. 570.5 Section 570.5 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE NONDISCRIMINATION IN THE OUTER CONTINENTAL SHELF § 570.5 Complaint. (a) Whenever any person believes that he or she has...

  4. 30 CFR 570.5 - Complaint.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Complaint. 570.5 Section 570.5 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE NONDISCRIMINATION IN THE OUTER CONTINENTAL SHELF § 570.5 Complaint. (a) Whenever any person believes that he or she has...

  5. 30 CFR 570.5 - Complaint.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Complaint. 570.5 Section 570.5 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE NONDISCRIMINATION IN THE OUTER CONTINENTAL SHELF § 570.5 Complaint. (a) Whenever any person believes that he or she has...

  6. 14 CFR 302.721 - Complaints.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Complaints. 302.721 Section 302.721 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL... Analysis, X-50, Department of Transportation, Washington, DC 20590, a complaint with respect to...

  7. 14 CFR 302.721 - Complaints.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Complaints. 302.721 Section 302.721 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL... Analysis, X-50, Department of Transportation, Washington, DC 20590, a complaint with respect to...

  8. 10 CFR 590.317 - Complaints.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Complaints. 590.317 Section 590.317 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS Procedures § 590.317 Complaints. (a) Any person may file...

  9. 29 CFR 1921.3 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Complaints. 1921.3 Section 1921.3 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED...' COMPENSATION ACT Prehearing Procedures § 1921.3 Complaints. (a) Issuance. The Deputy Solicitor of Labor...

  10. 21 CFR 225.115 - Complaint files.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Complaint files. 225.115 Section 225.115 Food and... CURRENT GOOD MANUFACTURING PRACTICE FOR MEDICATED FEEDS Records and Reports § 225.115 Complaint files. (a... feed manufacturer shall maintain on the premises a file which contains the following information:...

  11. Complaints Soar over Student-Loan Collections

    ERIC Educational Resources Information Center

    Field, Kelly

    2012-01-01

    Over the past five years, the number of complaints filed against agencies collecting on behalf of the U.S. Department of Education has grown by 45 percent. The Federal Trade Commission, which oversees the entire industry, received 142,743 complaints involving debt-collection companies last year, though only some involved student loans. Consumer…

  12. 43 CFR 17.331 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... or on behalf of others, may file a complaint with DOI, alleging discrimination prohibited by the Act... good cause shown, however, DOI may extend this time limit. (b) DOI will consider the date a complaint... described in paragraphs (a) and (c)(1) of this section. (c) DOI will attempt to facilitate the filing...

  13. 12 CFR 626.6030 - Complaints.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM NONDISCRIMINATION IN LENDING § 626.6030 Complaints. (a) Complaints regarding discrimination in lending by a Farm Credit institution under the Fair... States Department of Housing and Urban Development, Washington, DC 20410, and to the Office...

  14. 12 CFR 626.6030 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM NONDISCRIMINATION IN LENDING § 626.6030 Complaints. (a) Complaints regarding discrimination in lending by a Farm Credit institution under the Fair... States Department of Housing and Urban Development, Washington, DC 20410, and to the Office...

  15. 12 CFR 626.6030 - Complaints.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM NONDISCRIMINATION IN LENDING § 626.6030 Complaints. (a) Complaints regarding discrimination in lending by a Farm Credit institution under the Fair... States Department of Housing and Urban Development, Washington, DC 20410, and to the Office...

  16. 12 CFR 626.6030 - Complaints.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM NONDISCRIMINATION IN LENDING § 626.6030 Complaints. (a) Complaints regarding discrimination in lending by a Farm Credit institution under the Fair... States Department of Housing and Urban Development, Washington, DC 20410, and to the Office...

  17. 12 CFR 626.6030 - Complaints.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM NONDISCRIMINATION IN LENDING § 626.6030 Complaints. (a) Complaints regarding discrimination in lending by a Farm Credit institution under the Fair... States Department of Housing and Urban Development, Washington, DC 20410, and to the Office...

  18. 28 CFR 42.731 - Complaints.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... information necessary for further processing (i.e., identifies the parties involved, states the date when the complainant first learned of the alleged violation, and is signed by the complainant). (3) When a complaint is... recipient may request from the Department information regarding the complaint process. (e) Mediation....

  19. 39 CFR 952.5 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Complaints. 952.5 Section 952.5 Postal Service UNITED STATES POSTAL SERVICE PROCEDURES RULES OF PRACTICE IN PROCEEDINGS RELATIVE TO FALSE REPRESENTATION AND LOTTERY ORDERS § 952.5 Complaints. When the the Chief Postal Inspector or his or her...

  20. 12 CFR 308.506 - Complaint.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 5 2012-01-01 2012-01-01 false Complaint. 308.506 Section 308.506 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.506 Complaint. (a) On or after the date the...

  1. 12 CFR 308.506 - Complaint.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Complaint. 308.506 Section 308.506 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.506 Complaint. (a) On or after the date the...

  2. 12 CFR 308.506 - Complaint.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Complaint. 308.506 Section 308.506 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.506 Complaint. (a) On or after the date the...

  3. 12 CFR 308.506 - Complaint.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Complaint. 308.506 Section 308.506 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.506 Complaint. (a) On or after the date the...

  4. 12 CFR 308.506 - Complaint.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Complaint. 308.506 Section 308.506 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.506 Complaint. (a) On or after the date the...

  5. 10 CFR 590.317 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Complaints. 590.317 Section 590.317 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS Procedures § 590.317 Complaints. (a) Any person may file...

  6. 10 CFR 590.317 - Complaints.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Complaints. 590.317 Section 590.317 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS Procedures § 590.317 Complaints. (a) Any person may file...

  7. 49 CFR 1503.609 - Complaint.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Complaint. 1503.609 Section 1503.609 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION... must file the complaint with the Enforcement Docket Clerk in accordance with § 1503.429, or may file...

  8. 29 CFR 101.8 - Complaints.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 2 2011-07-01 2011-07-01 false Complaints. 101.8 Section 101.8 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD STATEMENTS OF PROCEDURES Unfair Labor Practice Cases Under Section 10 (a) to (i) of the Act and Telegraph Merger Act Cases § 101.8 Complaints. If the charge...

  9. 29 CFR 101.8 - Complaints.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 2 2012-07-01 2012-07-01 false Complaints. 101.8 Section 101.8 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD STATEMENTS OF PROCEDURES Unfair Labor Practice Cases Under Section 10 (a) to (i) of the Act and Telegraph Merger Act Cases § 101.8 Complaints. If the charge...

  10. 29 CFR 101.8 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Complaints. 101.8 Section 101.8 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD STATEMENTS OF PROCEDURES Unfair Labor Practice Cases Under Section 10 (a) to (i) of the Act and Telegraph Merger Act Cases § 101.8 Complaints. If the charge...

  11. 29 CFR 101.8 - Complaints.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 2 2013-07-01 2013-07-01 false Complaints. 101.8 Section 101.8 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD STATEMENTS OF PROCEDURES Unfair Labor Practice Cases Under Section 10 (a) to (i) of the Act and Telegraph Merger Act Cases § 101.8 Complaints. If the charge...

  12. 45 CFR 96.50 - Complaints.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... health services block grant, the Administrator, Alcohol, Drug Abuse, and Mental Health Administration... DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Enforcement § 96.50 Complaints... as required by this section. (b) Complaints with respect to the health block grants must be...

  13. 45 CFR 96.50 - Complaints.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... health services block grant, the Administrator, Alcohol, Drug Abuse, and Mental Health Administration... DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Enforcement § 96.50 Complaints... as required by this section. (b) Complaints with respect to the health block grants must be...

  14. 45 CFR 96.50 - Complaints.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... health services block grant, the Administrator, Alcohol, Drug Abuse, and Mental Health Administration... DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Enforcement § 96.50 Complaints... as required by this section. (b) Complaints with respect to the health block grants must be...

  15. 45 CFR 96.50 - Complaints.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... health services block grant, the Administrator, Alcohol, Drug Abuse, and Mental Health Administration... Department of Health and Human Services GENERAL ADMINISTRATION BLOCK GRANTS Enforcement § 96.50 Complaints... as required by this section. (b) Complaints with respect to the health block grants must be...

  16. 47 CFR 1.718 - Unsatisfied informal complaints; formal complaints relating back to the filing dates of informal...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... complaints relating back to the filing dates of informal complaints. 1.718 Section 1.718 Telecommunication... complaints relating back to the filing dates of informal complaints. When an informal complaint has not been... specified in § 1.721. Such filing will be deemed to relate back to the filing date of the informal...

  17. 47 CFR 1.718 - Unsatisfied informal complaints; formal complaints relating back to the filing dates of informal...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... complaints relating back to the filing dates of informal complaints. 1.718 Section 1.718 Telecommunication... complaints relating back to the filing dates of informal complaints. When an informal complaint has not been... specified in § 1.721. Such filing will be deemed to relate back to the filing date of the informal...

  18. Gastrointestinal Diseases in Pregnancy: Nausea, Vomiting, Hyperemesis Gravidarum, Gastroesophageal Reflux Disease, Constipation, and Diarrhea.

    PubMed

    Body, Cameron; Christie, Jennifer A

    2016-06-01

    Many disorders of the gastrointestinal tract are common in pregnancy. Elevated levels of progesterone may lead to alterations in gastrointestinal motility which could contribute to nausea, vomiting, and/or GERD. Pregnancy-induced diarrhea may be due to elevated levels prostaglandins. This article reviews the normal physiologic and structural changes associated with pregnancy that could contribute to many of the common gastrointestinal complaints in pregnant patients. Additionally, the appropriate clinical and laboratory evaluations, other pathologic conditions that should be included in the differential, as well as the nonpharmacologic and pharmacologic therapies for each of these conditions is discussed. PMID:27261898

  19. Open Science and Research Reproducibility

    PubMed Central

    Munafò, Marcus

    2016-01-01

    Many scientists, journals and funders are concerned about the low reproducibility of many scientific findings. One approach that may serve to improve the reliability and robustness of research is open science. Here I argue that the process of pre-registering study protocols, sharing study materials and data, and posting preprints of manuscripts may serve to improve quality control procedures at every stage of the research pipeline, and in turn improve the reproducibility of published work. PMID:27350794

  20. Comparison of Subjective Health Complaints between Chinese and German University Students: A Cross-Sectional Study.

    PubMed

    Chu, Janet Junqing; Khan, Mobarak Hossain; Jahn, Heiko J; Kraemer, Alexander

    2015-12-01

    High rates of health complaints (HCs) with substantial variation are reported in different university populations, which can be linked to socio-demographic, lifestyle-related factors, and cultural differences. HCs can be categorized into distinct components. This study aimed to identify and compare underlying dimensions of HCs (HC components); to access and compare HC prevalence, and the associations between HC components, socio-demographic, lifestyle-related factors, and perceived stress in German and Chinese university students. Two health surveys were conducted among 5159 university students (1853 Chinese, 3306 German). Factor analysis and logistic regression were applied. The prevalence of HC ranged from 4.6% to 40.2% over the two countries. Germans reported at least three HCs more often (47.2% vs. 35.8%). Chinese students more often reported gastrointestinal complaints. Perceived stress was positively associated with all three HC components in both countries (OR = 1.03-1.50) with stronger associations among Germans. Women more often reported HCs (OR = 1.32-2.43) with stronger associations among the Germans. Having a father with a low educational level was associated with high psychological symptoms among the Chinese (OR = 1.51), but with low gastrointestinal complaints among the Germans (OR = 0.79). The high prevalence of HCs in students requires country-specific interventions.

  1. Comparison of Subjective Health Complaints between Chinese and German University Students: A Cross-Sectional Study

    PubMed Central

    Chu, Janet Junqing; Khan, Mobarak Hossain; Jahn, Heiko J.; Kraemer, Alexander

    2015-01-01

    High rates of health complaints (HCs) with substantial variation are reported in different university populations, which can be linked to socio-demographic, lifestyle-related factors, and cultural differences. HCs can be categorized into distinct components. This study aimed to identify and compare underlying dimensions of HCs (HC components); to access and compare HC prevalence, and the associations between HC components, socio-demographic, lifestyle-related factors, and perceived stress in German and Chinese university students. Two health surveys were conducted among 5159 university students (1853 Chinese, 3306 German). Factor analysis and logistic regression were applied. The prevalence of HC ranged from 4.6% to 40.2% over the two countries. Germans reported at least three HCs more often (47.2% vs. 35.8%). Chinese students more often reported gastrointestinal complaints. Perceived stress was positively associated with all three HC components in both countries (OR = 1.03–1.50) with stronger associations among Germans. Women more often reported HCs (OR = 1.32–2.43) with stronger associations among the Germans. Having a father with a low educational level was associated with high psychological symptoms among the Chinese (OR = 1.51), but with low gastrointestinal complaints among the Germans (OR = 0.79). The high prevalence of HCs in students requires country-specific interventions. PMID:26690463

  2. Towards Reproducibility in Computational Hydrology

    NASA Astrophysics Data System (ADS)

    Hutton, Christopher; Wagener, Thorsten; Freer, Jim; Han, Dawei

    2016-04-01

    The ability to reproduce published scientific findings is a foundational principle of scientific research. Independent observation helps to verify the legitimacy of individual findings; build upon sound observations so that we can evolve hypotheses (and models) of how catchments function; and move them from specific circumstances to more general theory. The rise of computational research has brought increased focus on the issue of reproducibility across the broader scientific literature. This is because publications based on computational research typically do not contain sufficient information to enable the results to be reproduced, and therefore verified. Given the rise of computational analysis in hydrology over the past 30 years, to what extent is reproducibility, or a lack thereof, a problem in hydrology? Whilst much hydrological code is accessible, the actual code and workflow that produced and therefore documents the provenance of published scientific findings, is rarely available. We argue that in order to advance and make more robust the process of hypothesis testing and knowledge creation within the computational hydrological community, we need to build on from existing open data initiatives and adopt common standards and infrastructures to: first make code re-useable and easy to find through consistent use of metadata; second, publish well documented workflows that combine re-useable code together with data to enable published scientific findings to be reproduced; finally, use unique persistent identifiers (e.g. DOIs) to reference re-useable and reproducible code, thereby clearly showing the provenance of published scientific findings. Whilst extra effort is require to make work reproducible, there are benefits to both the individual and the broader community in doing so, which will improve the credibility of the science in the face of the need for societies to adapt to changing hydrological environments.

  3. 32 CFR 776.79 - The complaint.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., professionally, or morally unqualified to perform his or her duties; and (3) Contain a complete, factual statement of the acts or omissions constituting the substance of the complaint, as well as a description...

  4. 45 CFR 96.50 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Services Administration. Complaints with respect to the social services block grant must be submitted in..., the response will state the reasons why additional time is necessary. Under the low-income home...

  5. 40 CFR 22.14 - Complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., or any part thereof, without prejudice one time before the answer has been filed. After one... complaint, or any part thereof, without prejudice only upon motion granted by the Presiding Officer....

  6. 14 CFR 302.721 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... fifteen (15) days of the filing of a contract, any interested person may file with the Office of Aviation Analysis, X-50, Department of Transportation, Washington, DC 20590, a complaint with respect to...

  7. Canada files WTO complaint against EC.

    PubMed

    2000-01-01

    In December 1998, Canada filed a complaint alleging that the European Communities (EC) had adopted regulations that amounted to a scheme to extend patent terms, limited to pharmaceutical and agricultural chemical products.

  8. Latent fingermark pore area reproducibility.

    PubMed

    Gupta, A; Buckley, K; Sutton, R

    2008-08-01

    The study of the reproducibility of friction ridge pore detail in fingermarks is a measure of their usefulness in personal identification. Pore area in latent prints developed using cyanoacrylate and ninhydrin were examined and measured by photomicrography using appropriate software tools. The data were analysed statistically and the results showed that pore area is not reproducible in developed latent prints, using either of the development techniques. The results add further support to the lack of reliability of pore area in personal identification. PMID:18617339

  9. Rotary head type reproducing apparatus

    DOEpatents

    Takayama, Nobutoshi; Edakubo, Hiroo; Kozuki, Susumu; Takei, Masahiro; Nagasawa, Kenichi

    1986-01-01

    In an apparatus of the kind arranged to reproduce, with a plurality of rotary heads, an information signal from a record bearing medium having many recording tracks which are parallel to each other with the information signal recorded therein and with a plurality of different pilot signals of different frequencies also recorded one by one, one in each of the recording tracks, a plurality of different reference signals of different frequencies are simultaneously generated. A tracking error is detected by using the different reference signals together with the pilot signals which are included in signals reproduced from the plurality of rotary heads.

  10. Gastrointestinal motility and functional gastrointestinal diseases.

    PubMed

    Kusano, Motoyasu; Hosaka, Hiroko; Kawada, Akiyo; Kuribayashi, Shiko; Shimoyama, Yasuyuki; Zai, Hiroaki; Kawamura, Osamu; Yamada, Masanobu

    2014-01-01

    Digestive tract motility patterns are closely related to the pathophysiology of functional gastrointestinal diseases (FGID), and these patterns differ markedly between the interdigestive period and the postprandial period. The characteristic motility pattern in the interdigestive period is so-called interdigestive migrating contraction (IMC). IMCs have a housekeeping role in the intestinal tract, and could also be related to FGID. IMCs arising from the stomach are called gastrointestinal IMCs (GI-IMC), while IMCs arising from the duodenum without associated gastric contractions are called intestinal IMCs (I-IMC). It is thought that I-IMCs are abnormal in FGID. Transport of food residue to the duodenum via gastric emptying is one of the most important postprandial functions of the stomach. In patients with functional dyspepsia (FD), abnormal gastric emptying is a possible mechanism of gastric dysfunction. Accordingly, delayed gastric emptying has attracted attention, with prokinetic agents and herbal medicines often being administered in Japan to accelerate gastric emptying in patients who have anorexia associated with dyspepsia. Recently, we found that addition of monosodium L-glutamate (MSG) to a high-calorie liquid diet rich in casein promoted gastric emptying in healthy men. Therefore, another potential method of improving delayed gastric emptying could be activation of chemosensors that stimulate the autonomic nervous system of the gastrointestinal tract, suggesting a role for MSG in the management of delayed gastric emptying in patients with FD.

  11. Citizen complaints and environmental regulation of Michigan livestock operations.

    PubMed

    Hadrich, J C; Wolf, C A

    2011-01-01

    Citizen environmental complaints filed against agricultural producers in Michigan were examined to determine farm and community factors influencing citizen complaints and the subsequent response of the farmer. Secondary citizen environmental complaint data were obtained from the Michigan Department of Agriculture from 1998 to 2007 with 1,289 observations. Citizen complaints were grouped into 5 categories: odor, surface water, ground water, combination, and other complaints. Complaints were further classified as nonverified or verified where verified meant that the inspected farm was not complying with relevant generally accepted agricultural and management practices. These data were used to examine how farm characteristics affected the likelihood of a verified complaint. Odor and surface water complaints accounted for 75% of all complaints. A probit regression analysis was used to estimate the probability of a verified complaint as a function of complaint type, farm characteristics, county characteristics, and seasonal factors. Results from the probit regression analysis revealed that larger operations, poultry, and hog farms received more nonverified complaints than other livestock farms. Surface water issues were 17% more likely to be verified complaints compared with odor issues, of which the surface water complaints often originated from sources other than neighbors. In contrast, odor issues were more likely to result from accepted management practices requiring no mitigation. Farms that received a verified citizen complaint were required to mitigate the complaint by implementing corrective practices. A log-level (log Y) regression was used to evaluate how farm characteristics influenced the cost to implement corrective practices on those farms receiving a verified citizen complaint. Costs to implement corrective practices to mitigate verified complaints were greatest for dairy operations and surface water complaints. Corrective practices required to mitigate a

  12. Citizen complaints and environmental regulation of Michigan livestock operations.

    PubMed

    Hadrich, J C; Wolf, C A

    2011-01-01

    Citizen environmental complaints filed against agricultural producers in Michigan were examined to determine farm and community factors influencing citizen complaints and the subsequent response of the farmer. Secondary citizen environmental complaint data were obtained from the Michigan Department of Agriculture from 1998 to 2007 with 1,289 observations. Citizen complaints were grouped into 5 categories: odor, surface water, ground water, combination, and other complaints. Complaints were further classified as nonverified or verified where verified meant that the inspected farm was not complying with relevant generally accepted agricultural and management practices. These data were used to examine how farm characteristics affected the likelihood of a verified complaint. Odor and surface water complaints accounted for 75% of all complaints. A probit regression analysis was used to estimate the probability of a verified complaint as a function of complaint type, farm characteristics, county characteristics, and seasonal factors. Results from the probit regression analysis revealed that larger operations, poultry, and hog farms received more nonverified complaints than other livestock farms. Surface water issues were 17% more likely to be verified complaints compared with odor issues, of which the surface water complaints often originated from sources other than neighbors. In contrast, odor issues were more likely to result from accepted management practices requiring no mitigation. Farms that received a verified citizen complaint were required to mitigate the complaint by implementing corrective practices. A log-level (log Y) regression was used to evaluate how farm characteristics influenced the cost to implement corrective practices on those farms receiving a verified citizen complaint. Costs to implement corrective practices to mitigate verified complaints were greatest for dairy operations and surface water complaints. Corrective practices required to mitigate a

  13. 14 CFR 16.21 - Pre-complaint resolution.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Pre-complaint resolution. 16.21 Section 16... to Complaints § 16.21 Pre-complaint resolution. (a) Prior to filing a complaint under this part, a... responsible for the noncompliance. These efforts at informal resolution may include, without limitation,...

  14. 47 CFR 1.1406 - Dismissal of complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Dismissal of complaints. 1.1406 Section 1.1406 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Pole Attachment Complaint Procedures § 1.1406 Dismissal of complaints. (a) The complaint shall be dismissed for lack of jurisdiction...

  15. 41 CFR 105-8.170-6 - Acceptance of complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Acceptance of complaint... Acceptance of complaint. (a) The Official shall accept a complete complaint that is filed in accordance with... the respondent of receipt and acceptance of the complaint. (b) If the Official receives a...

  16. 29 CFR 1603.102 - Filing a complaint.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE GOVERNMENT EMPLOYEE RIGHTS ACT OF 1991 Administrative Process § 1603.102 Filing a complaint. (a... appear in 29 CFR 1610.4. (c) Contents of a complaint. A complaint shall be in writing, signed...

  17. 5 CFR 2423.25 - Post complaint, prehearing settlements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Post complaint, prehearing settlements... Post Complaint, Prehearing Procedures § 2423.25 Post complaint, prehearing settlements. (a) Informal and formal settlements. Post complaint settlements may be either informal or formal. (1)...

  18. 5 CFR 2423.25 - Post complaint, prehearing settlements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Post complaint, prehearing settlements... Post Complaint, Prehearing Procedures § 2423.25 Post complaint, prehearing settlements. (a) Informal and formal settlements. Post complaint settlements may be either informal or formal. (1)...

  19. Managing patient complaints in China: a qualitative study in Shanghai

    PubMed Central

    Jiang, Yishi; Ying, Xiaohua; Zhang, Qian; Tang, Sirui Rae; Kane, Sumit; Mukhopadhyay, Maitrayee; Qian, Xu

    2014-01-01

    Objectives To examine the handling system for patient complaints and to identify existing barriers that are associated with effective management of patient complaints in China. Setting Key stakeholders of the handling system for patient complaints at the national, Shanghai municipal and hospital levels in China. Participants 35 key informants including policymakers, hospital managers, healthcare providers, users and other stakeholders in Shanghai. Primary and secondary outcome measures Semistructured interviews were conducted to understand the process of handling patient complaints and factors affecting the process and outcomes of patient complaint management. Results The Chinese handling system for patient complaints was established in the past decade. Hospitals shoulder the most responsibility of patient complaint handling. Barriers to effective management of patient complaints included service users’ low awareness of the systems in the initial stage of the process; poor capacity and skills of healthcare providers, incompetence and powerlessness of complaint handlers and non-transparent exchange of information during the process of complaint handling; conflicts between relevant actors and regulations and unjustifiable complaints by patients during solution settlements; and weak enforcement of regulations, deficient information for managing patient complaints and unwillingness of the hospitals to effectively handle complaints in the postcomplaint stage. Conclusions Barriers to the effective management of patient complaints vary at the different stages of complaint handling and perspectives on these barriers differ between the service users and providers. Information, procedure design, human resources, system arrangement, unified legal system and regulations and factors shaping the social context all play important roles in effective patient complaint management. PMID:25146715

  20. 5 CFR 2423.25 - Post complaint, prehearing settlements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Post complaint, prehearing settlements... Post Complaint, Prehearing Procedures § 2423.25 Post complaint, prehearing settlements. (a) Informal and formal settlements. Post complaint settlements may be either informal or formal. (1)...

  1. 29 CFR 2700.36 - Contents of complaint.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false Contents of complaint. 2700.36 Section 2700.36 Labor Regulations Relating to Labor (Continued) FEDERAL MINE SAFETY AND HEALTH REVIEW COMMISSION PROCEDURAL RULES Complaints for Compensation § 2700.36 Contents of complaint. A complaint for compensation shall include:...

  2. Reproducible Bioinformatics Research for Biologists

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This book chapter describes the current Big Data problem in Bioinformatics and the resulting issues with performing reproducible computational research. The core of the chapter provides guidelines and summaries of current tools/techniques that a noncomputational researcher would need to learn to pe...

  3. Reproducible Research in Computational Science

    PubMed Central

    Peng, Roger D.

    2012-01-01

    Computational science has led to exciting new developments, but the nature of the work has exposed limitations in our ability to evaluate published findings. Reproducibility has the potential to serve as a minimum standard for judging scientific claims when full independent replication of a study is not possible. PMID:22144613

  4. Reproducible research in computational science.

    PubMed

    Peng, Roger D

    2011-12-01

    Computational science has led to exciting new developments, but the nature of the work has exposed limitations in our ability to evaluate published findings. Reproducibility has the potential to serve as a minimum standard for judging scientific claims when full independent replication of a study is not possible.

  5. Performance reproducibility index for classification

    PubMed Central

    Yousefi, Mohammadmahdi R.; Dougherty, Edward R.

    2012-01-01

    Motivation: A common practice in biomarker discovery is to decide whether a large laboratory experiment should be carried out based on the results of a preliminary study on a small set of specimens. Consideration of the efficacy of this approach motivates the introduction of a probabilistic measure, for whether a classifier showing promising results in a small-sample preliminary study will perform similarly on a large independent sample. Given the error estimate from the preliminary study, if the probability of reproducible error is low, then there is really no purpose in substantially allocating more resources to a large follow-on study. Indeed, if the probability of the preliminary study providing likely reproducible results is small, then why even perform the preliminary study? Results: This article introduces a reproducibility index for classification, measuring the probability that a sufficiently small error estimate on a small sample will motivate a large follow-on study. We provide a simulation study based on synthetic distribution models that possess known intrinsic classification difficulties and emulate real-world scenarios. We also set up similar simulations on four real datasets to show the consistency of results. The reproducibility indices for different distributional models, real datasets and classification schemes are empirically calculated. The effects of reporting and multiple-rule biases on the reproducibility index are also analyzed. Availability: We have implemented in C code the synthetic data distribution model, classification rules, feature selection routine and error estimation methods. The source code is available at http://gsp.tamu.edu/Publications/supplementary/yousefi12a/. Supplementary simulation results are also included. Contact: edward@ece.tamu.edu Supplementary Information: Supplementary data are available at Bioinformatics online. PMID:22954625

  6. 47 CFR 7.22 - Formal complaints based on unsatisfied informal complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Formal complaints based on unsatisfied informal complaints. 7.22 Section 7.22 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL ACCESS TO VOICEMAIL AND INTERACTIVE MENU SERVICES AND EQUIPMENT BY PEOPLE WITH DISABILITIES Enforcement § 7.22...

  7. 47 CFR 7.22 - Formal complaints based on unsatisfied informal complaints.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Formal complaints based on unsatisfied informal complaints. 7.22 Section 7.22 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL ACCESS TO VOICEMAIL AND INTERACTIVE MENU SERVICES AND EQUIPMENT BY PEOPLE WITH DISABILITIES Enforcement § 7.22...

  8. 47 CFR 7.22 - Formal complaints based on unsatisfied informal complaints.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Formal complaints based on unsatisfied informal complaints. 7.22 Section 7.22 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL ACCESS TO VOICEMAIL AND INTERACTIVE MENU SERVICES AND EQUIPMENT BY PEOPLE WITH DISABILITIES Enforcement § 7.22...

  9. 47 CFR 6.22 - Formal complaints based on unsatisfied informal complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Formal complaints based on unsatisfied informal complaints. 6.22 Section 6.22 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL ACCESS TO TELECOMMUNICATIONS SERVICE, TELECOMMUNICATIONS EQUIPMENT AND CUSTOMER PREMISES EQUIPMENT BY PERSONS WITH...

  10. Reproducibility of NIF hohlraum measurements

    NASA Astrophysics Data System (ADS)

    Moody, J. D.; Ralph, J. E.; Turnbull, D. P.; Casey, D. T.; Albert, F.; Bachmann, B. L.; Doeppner, T.; Divol, L.; Grim, G. P.; Hoover, M.; Landen, O. L.; MacGowan, B. J.; Michel, P. A.; Moore, A. S.; Pino, J. E.; Schneider, M. B.; Tipton, R. E.; Smalyuk, V. A.; Strozzi, D. J.; Widmann, K.; Hohenberger, M.

    2015-11-01

    The strategy of experimentally ``tuning'' the implosion in a NIF hohlraum ignition target towards increasing hot-spot pressure, areal density of compressed fuel, and neutron yield relies on a level of experimental reproducibility. We examine the reproducibility of experimental measurements for a collection of 15 identical NIF hohlraum experiments. The measurements include incident laser power, backscattered optical power, x-ray measurements, hot-electron fraction and energy, and target characteristics. We use exact statistics to set 1-sigma confidence levels on the variations in each of the measurements. Of particular interest is the backscatter and laser-induced hot-spot locations on the hohlraum wall. Hohlraum implosion designs typically include variability specifications [S. W. Haan et al., Phys. Plasmas 18, 051001 (2011)]. We describe our findings and compare with the specifications. This work was performed under the auspices of the U.S. Department of Energy by University of California, Lawrence Livermore National Laboratory under Contract W-7405-Eng-48.

  11. Cloning to reproduce desired genotypes.

    PubMed

    Westhusin, M E; Long, C R; Shin, T; Hill, J R; Looney, C R; Pryor, J H; Piedrahita, J A

    2001-01-01

    Cloned sheep, cattle, goats, pigs and mice have now been produced using somatic cells for nuclear transplantation. Animal cloning is still very inefficient with on average less than 10% of the cloned embryos transferred resulting in a live offspring. However successful cloning of a variety of different species and by a number of different laboratory groups has generated tremendous interest in reproducing desired genotypes. Some of these specific genotypes represent animal cell lines that have been genetically modified. In other cases there is a significant demand for cloning animals characterized by their inherent genetic value, for example prize livestock, household pets and rare or endangered species. A number of different variables may influence the ability to reproduce a specific genotype by cloning. These include species, source of recipient ova, cell type of nuclei donor, treatment of donor cells prior to nuclear transfer, and the techniques employed for nuclear transfer. At present, there is no solid evidence that suggests cloning will be limited to only a few specific animals, and in fact, most data collected to date suggests cloning will be applicable to a wide variety of different animals. The ability to reproduce any desired genotype by cloning will ultimately depend on the amount of time and resources invested in research.

  12. Heritable Gastrointestinal Cancer Syndromes.

    PubMed

    Stoffel, Elena M

    2016-09-01

    Although almost all gastrointestinal cancers develop from sporadic genomic events, approximately 5% arise from germline mutations in genes associated with cancer predisposition. The number of these genes continues to increase. Tumor phenotypes and family history provide the framework for identifying at-risk individuals. The diagnosis of a hereditary cancer syndrome has implications for management of patients and their families. Systematic approaches that integrate family history and molecular characterization of tumors and polyps facilitate identification of individuals with this genetic predisposition. This article summarizes diagnosis and management of hereditary cancer syndromes associated with gastrointestinal cancers. PMID:27546846

  13. Neurochemical mechanisms and pharmacologic strategies in managing nausea and vomiting related to cyclic vomiting syndrome and other gastrointestinal disorders.

    PubMed

    Bashashati, Mohammad; McCallum, Richard W

    2014-01-01

    Nausea and vomiting are common gastrointestinal complaints which could be triggered by stimuli in both the peripheral and central nervous systems. They may be considered as defense mechanisms when threatening toxins/agents enter the gastrointestinal tract or there is excessive retention of gastrointestinal contents due to obstruction. The pathophysiology of nausea and vomiting is complex and much still remains unknown. Therefore, treatments are restricted or ineffective in many cases. Nausea and vomiting with functional etiologies including cyclic vomiting syndrome are challenging in gastroenterology. In this article, we review potential pathways, neurochemical transmitters, and their receptors which are possibly involved in the pathophysiology of nausea and vomiting including the entity cyclic vomiting syndrome.

  14. What Are Gastrointestinal Stromal Tumors?

    MedlinePlus

    ... the digestive system. The gastrointestinal system The gastrointestinal (GI) system (or digestive system) processes food for energy ... bloodstream. This is the longest section of the GI tract, measuring more than 20 feet. The small ...

  15. Pediatric functional gastrointestinal disorders

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Functional gastrointestinal disorders continue to be a prevalent set of conditions faced by the healthcare team and have a significant emotional and economic impact. In this review, the authors highlight some of the common functional disorders seen in pediatric patients (functional dyspepsia, irrita...

  16. Gastrointestinal Bleeding in Athletes.

    ERIC Educational Resources Information Center

    Eichner, Edward R.

    1989-01-01

    Describes the scope and importance of gastrointestinal bleeding in runners and other athletes, discussing causes, sites, and implications of exercise-related bleeding. Practical tips to mitigate the problem, potentially more troublesome in women because of lower iron stores, are presented (e.g., gradual conditioning and avoidance of prerace…

  17. Gastrointestinal endoscopy in pregnancy.

    PubMed

    Savas, Nurten

    2014-11-01

    Gastrointestinal endoscopy has a major diagnostic and therapeutic role in most gastrointestinal disorders; however, limited information is available about clinical efficacy and safety in pregnant patients. The major risks of endoscopy during pregnancy include potential harm to the fetus because of hypoxia, premature labor, trauma and teratogenesis. In some cases, endoscopic procedures may be postponed until after delivery. When emergency or urgent indications are present, endoscopic procedures may be considered with some precautions. United States Food and Drug Administration category B drugs may be used in low doses. Endoscopic procedures during pregnancy may include upper gastrointestinal endoscopy, percutaneous endoscopic gastrostomy, sigmoidoscopy, colonoscopy, enteroscopy of the small bowel or video capsule endoscopy, endoscopic retrograde cholangiopancreatography and endoscopic ultrasonography. All gastrointestinal endoscopic procedures in pregnant patients should be performed in hospitals by expert endoscopists and an obstetrician should be informed about all endoscopic procedures. The endoscopy and flexible sigmoidoscopy may be safe for the fetus and pregnant patient, and may be performed during pregnancy when strong indications are present. Colonoscopy for pregnant patients may be considered for strong indications during the second trimester. Although therapeutic endoscopic retrograde cholangiopancreatography may be considered during pregnancy, this procedure should be performed only for strong indications and attempts should be made to minimize radiation exposure.

  18. [Gastrointestinal and hepatic diseases].

    PubMed

    Moctezuma-Velázquez, Carlos; Aguirre-Valadez, Jonathan

    2016-09-01

    Diet is considered an important triggering factor for gastrointestinal symptoms whose physiopathology includes not only measurable, inflammatory reactions, but also functional disorders, where no organic effects may be measured or demonstrated. Moreover, the prevalence of the perceived intolerance to certain foods ranges from 20-25% (within the general population) to 50-70% in diseases like irritable bowel syndrome. This intolerance has been observed particularly after the consumption of milk and dairy products, which are frequently considered as causative of gastrointestinal symptoms, thus limiting their ingestion. However, this behavior reduces the dietary sources of calcium and consequently may lead to malnutrition and bone decalcification, amongst other complications. The true dairy intolerance (intestinal lactase deficiency) explains most of the symptoms ensuing their consumption, but the frequency of such alteration on the different gastrointestinal diseases has not been determined. This review focuses on the most frequent gastrointestinal diseases and the existing evidence regarding the alterations and symptoms related to the consumption of milk or dairy products. PMID:27603892

  19. Apollo gastrointestinal analysis

    NASA Technical Reports Server (NTRS)

    Nichols, B. L.; Huang, C. T. L.

    1975-01-01

    Fecal bile acid patterns for the Apollo 17 flight were studied to determine the cause of diarrhea on the mission. The fecal sterol analysis gave no indication of an infectious diarrhea, or specific, or nonspecific etiology occurring during the entire flight. It is assumed that the gastrointestinal problems encountered are the consequences of altered physiology, perhaps secondary to physical or emotional stress of flight.

  20. Gastrointestinal endoscopy in pregnancy

    PubMed Central

    Savas, Nurten

    2014-01-01

    Gastrointestinal endoscopy has a major diagnostic and therapeutic role in most gastrointestinal disorders; however, limited information is available about clinical efficacy and safety in pregnant patients. The major risks of endoscopy during pregnancy include potential harm to the fetus because of hypoxia, premature labor, trauma and teratogenesis. In some cases, endoscopic procedures may be postponed until after delivery. When emergency or urgent indications are present, endoscopic procedures may be considered with some precautions. United States Food and Drug Administration category B drugs may be used in low doses. Endoscopic procedures during pregnancy may include upper gastrointestinal endoscopy, percutaneous endoscopic gastrostomy, sigmoidoscopy, colonoscopy, enteroscopy of the small bowel or video capsule endoscopy, endoscopic retrograde cholangiopancreatography and endoscopic ultrasonography. All gastrointestinal endoscopic procedures in pregnant patients should be performed in hospitals by expert endoscopists and an obstetrician should be informed about all endoscopic procedures. The endoscopy and flexible sigmoidoscopy may be safe for the fetus and pregnant patient, and may be performed during pregnancy when strong indications are present. Colonoscopy for pregnant patients may be considered for strong indications during the second trimester. Although therapeutic endoscopic retrograde cholangiopancreatography may be considered during pregnancy, this procedure should be performed only for strong indications and attempts should be made to minimize radiation exposure. PMID:25386072

  1. Haemochromatosis and gastrointestinal cancer.

    PubMed

    Lagergren, Katarina; Wahlin, Karl; Mattsson, Fredrik; Alderson, Derek; Lagergren, Jesper

    2016-10-15

    Iron overload in patients with haemochromatosis is a strong risk factor for liver cancer, but its influence on other gastrointestinal cancer risk is unclear. The aim was to assess the relative risk of luminal gastrointestinal cancer among patients diagnosed with haemochromatosis. This population-based, nationwide Swedish cohort study included patients with haemochromatosis in Sweden in 1965-2013. The incidence of gastrointestinal cancers was assessed through the Swedish Cancer Registry. The measure of relative risk was the standardised incidence ratio (SIR) with 95% confidence interval (CI), that is, the ratio of the observed number of gastrointestinal cancers in the haemochromatosis cohort divided by the expected number of such cancers, calculated from the entire corresponding background population of Sweden. Among 6,849 patients in the haemochromatosis cohort with up to 48 years of follow-up, the SIRs were 3-fold increased for oesophageal squamous cell carcinoma (SIR = 3.2, 95% CI 1.3-6.6; n = 7) and 40% increased for colon adenocarcinoma (SIR = 1.4, 95% CI 1.1-1.9; n = 54). No associations were found between haemochromatosis and the risk of adenocarcinoma of the oesophagus (SIR = 0.5, 95% CI 0.0-2.5; n = 1), stomach (SIR = 0.7, 95% CI 0.3-1.4; n = 8), small bowel (SIR = 1.2, 95% CI 0.0-6.7; n = 1) or rectum (SIR = 1.0, 95% CI 0.6-1.6; n = 21). These findings indicate that haemochromatosis increases the risk of oesophageal squamous cell carcinoma and colon adenocarcinoma, but might not influence the risk of other types of luminal gastrointestinal cancer. These findings should encourage further research examining the role of iron overload in cancer aetiology.

  2. 10 CFR 4.42 - Complaints.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Complaints. 4.42 Section 4.42 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL... believes himself or any specific class of individuals to be subjected to discrimination prohibited by...

  3. 10 CFR 4.42 - Complaints.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Complaints. 4.42 Section 4.42 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL... believes himself or any specific class of individuals to be subjected to discrimination prohibited by...

  4. 10 CFR 4.42 - Complaints.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Complaints. 4.42 Section 4.42 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL... believes himself or any specific class of individuals to be subjected to discrimination prohibited by...

  5. 32 CFR 776.79 - The complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false The complaint. 776.79 Section 776.79 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY MISCELLANEOUS RULES PROFESSIONAL CONDUCT... the ethical standards of the profession; or (ii) The covered attorney concerned is...

  6. 40 CFR 209.5 - Complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS RULES OF PRACTICE GOVERNING PROCEEDINGS UNDER THE NOISE CONTROL ACT OF 1972 Rules of Practice Governing Hearings for Orders Issued Under Section 11(d) of the Noise Control Act § 209.5 Complaint. (a) Contents. The...

  7. 40 CFR 209.5 - Complaint.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS RULES OF PRACTICE GOVERNING PROCEEDINGS UNDER THE NOISE CONTROL ACT OF 1972 Rules of Practice Governing Hearings for Orders Issued Under Section 11(d) of the Noise Control Act § 209.5 Complaint. (a) Contents. The...

  8. 40 CFR 209.5 - Complaint.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS RULES OF PRACTICE GOVERNING PROCEEDINGS UNDER THE NOISE CONTROL ACT OF 1972 Rules of Practice Governing Hearings for Orders Issued Under Section 11(d) of the Noise Control Act § 209.5 Complaint. (a) Contents. The...

  9. 40 CFR 209.5 - Complaint.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS RULES OF PRACTICE GOVERNING PROCEEDINGS UNDER THE NOISE CONTROL ACT OF 1972 Rules of Practice Governing Hearings for Orders Issued Under Section 11(d) of the Noise Control Act § 209.5 Complaint. (a) Contents. The...

  10. 40 CFR 209.5 - Complaint.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS RULES OF PRACTICE GOVERNING PROCEEDINGS UNDER THE NOISE CONTROL ACT OF 1972 Rules of Practice Governing Hearings for Orders Issued Under Section 11(d) of the Noise Control Act § 209.5 Complaint. (a) Contents. The...

  11. 76 FR 52718 - Complaint About Postal Services

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-23

    ... Online system at https://www.prc.gov/prc-pages/filing-online/login.aspx . Commenters who cannot submit... impetus for the Complaint stems from three developments that span more than 5 years. The first was a... of settlement within 30 days of the issuance of this order. V. Ordering Paragraphs It is ordered:...

  12. 41 CFR 50-201.1202 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Complaints. 50-201.1202 Section 50-201.1202 Public Contracts and Property Management Other Provisions Relating to Public Contracts... officer or employee of the United States Government or of any agency thereof has any knowledge of,...

  13. 19 CFR 210.12 - The complaint.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... Relevant information includes but is not limited to: (A) Significant investment in plant and equipment; (B..., state a specific theory and provide corroborating data to support the allegation(s) in the complaint... United States. The information that should ordinarily be provided includes the volume and trend...

  14. 19 CFR 210.12 - The complaint.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... Relevant information includes but is not limited to: (A) Significant investment in plant and equipment; (B..., state a specific theory and provide corroborating data to support the allegation(s) in the complaint... United States. The information that should ordinarily be provided includes the volume and trend...

  15. 19 CFR 210.12 - The complaint.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... future), and including the relevant operations of any licensees. Relevant information includes but is not... a specific theory and provide corroborating data to support the allegation(s) in the complaint... United States. The information that should ordinarily be provided includes the volume and trend...

  16. 41 CFR 50-201.1202 - Complaints.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 1 2012-07-01 2009-07-01 true Complaints. 50-201.1202 Section 50-201.1202 Public Contracts and Property Management Other Provisions Relating to Public Contracts... officer or employee of the United States Government or of any agency thereof has any knowledge of,...

  17. 41 CFR 50-201.1202 - Complaints.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 1 2014-07-01 2014-07-01 false Complaints. 50-201.1202 Section 50-201.1202 Public Contracts and Property Management Other Provisions Relating to Public Contracts... officer or employee of the United States Government or of any agency thereof has any knowledge of,...

  18. 13 CFR 117.11 - Complaint procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... The complainant has the right to have a representative at all stages of the complaint procedure. (b) A... Opportunity & Civil Rights Compliance, are the only officials who may waive the 180-day time limit for filing... and the date the complainant first had knowledge of the alleged violation, describes generally...

  19. 45 CFR 98.32 - Parental complaints.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Parental complaints. 98.32 Section 98.32 Public Welfare Department of Health and Human Services GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Parental Rights and Responsibilities § 98.32 Parental...

  20. 45 CFR 98.32 - Parental complaints.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Parental complaints. 98.32 Section 98.32 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Parental Rights and Responsibilities § 98.32 Parental...

  1. 45 CFR 98.32 - Parental complaints.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Parental complaints. 98.32 Section 98.32 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Parental Rights and Responsibilities § 98.32 Parental...

  2. 45 CFR 98.32 - Parental complaints.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Parental complaints. 98.32 Section 98.32 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Parental Rights and Responsibilities § 98.32 Parental...

  3. 45 CFR 98.32 - Parental complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Parental complaints. 98.32 Section 98.32 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Program Operations (Child Care Services)-Parental Rights and Responsibilities § 98.32 Parental...

  4. 29 CFR 458.60 - Actionable complaint.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 2 2011-07-01 2011-07-01 false Actionable complaint. 458.60 Section 458.60 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR STANDARDS OF CONDUCT STANDARDS OF CONDUCT Proceedings for Enforcing Standards of Conduct Procedures Involving Bill of Rights...

  5. 29 CFR 458.60 - Actionable complaint.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 2 2014-07-01 2014-07-01 false Actionable complaint. 458.60 Section 458.60 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR STANDARDS OF CONDUCT STANDARDS OF CONDUCT Proceedings for Enforcing Standards of Conduct Procedures Involving Bill of Rights...

  6. 29 CFR 458.60 - Actionable complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Actionable complaint. 458.60 Section 458.60 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR STANDARDS OF CONDUCT STANDARDS OF CONDUCT Proceedings for Enforcing Standards of Conduct Procedures Involving Bill of Rights...

  7. 29 CFR 458.60 - Actionable complaint.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 2 2013-07-01 2013-07-01 false Actionable complaint. 458.60 Section 458.60 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR STANDARDS OF CONDUCT STANDARDS OF CONDUCT Proceedings for Enforcing Standards of Conduct Procedures Involving Bill of Rights...

  8. 29 CFR 458.60 - Actionable complaint.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 2 2012-07-01 2012-07-01 false Actionable complaint. 458.60 Section 458.60 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR STANDARDS OF CONDUCT STANDARDS OF CONDUCT Proceedings for Enforcing Standards of Conduct Procedures Involving Bill of Rights...

  9. 20 CFR 405.30 - Discrimination complaints.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Discrimination complaints. 405.30 Section 405... INITIAL DISABILITY CLAIMS Introduction, General Description, and Definitions § 405.30 Discrimination... that an adjudicator has improperly discriminated against you, you may file a discrimination...

  10. 20 CFR 405.30 - Discrimination complaints.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Discrimination complaints. 405.30 Section 405... INITIAL DISABILITY CLAIMS Introduction, General Description, and Definitions § 405.30 Discrimination... that an adjudicator has improperly discriminated against you, you may file a discrimination...

  11. 20 CFR 405.30 - Discrimination complaints.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Discrimination complaints. 405.30 Section 405... INITIAL DISABILITY CLAIMS Introduction, General Description, and Definitions § 405.30 Discrimination... that an adjudicator has improperly discriminated against you, you may file a discrimination...

  12. 20 CFR 405.30 - Discrimination complaints.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Discrimination complaints. 405.30 Section 405... INITIAL DISABILITY CLAIMS Introduction, General Description, and Definitions § 405.30 Discrimination... that an adjudicator has improperly discriminated against you, you may file a discrimination...

  13. 20 CFR 405.30 - Discrimination complaints.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Discrimination complaints. 405.30 Section 405... INITIAL DISABILITY CLAIMS Introduction, General Description, and Definitions § 405.30 Discrimination... that an adjudicator has improperly discriminated against you, you may file a discrimination...

  14. 12 CFR 528.8 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., Washington, DC 20410 for processing under the Fair Housing Act, and to the Director, Consumer Affairs, Office of Thrift Supervision, Washington, DC 20552 for processing under Office regulations. Complaints... Opportunity Commission, Washington, DC 20506 and a copy, for information only, sent to the Director,...

  15. 12 CFR 528.8 - Complaints.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., Washington, DC 20410 for processing under the Fair Housing Act, and to the Director, Consumer Affairs, Office of Thrift Supervision, Washington, DC 20552 for processing under Office regulations. Complaints... Opportunity Commission, Washington, DC 20506 and a copy, for information only, sent to the Director,...

  16. 12 CFR 528.8 - Complaints.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., Washington, DC 20410 for processing under the Fair Housing Act, and to the Director, Consumer Affairs, Office of Thrift Supervision, Washington, DC 20552 for processing under Office regulations. Complaints... Opportunity Commission, Washington, DC 20506 and a copy, for information only, sent to the Director,...

  17. 12 CFR 528.8 - Complaints.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., Washington, DC 20410 for processing under the Fair Housing Act, and to the Director, Consumer Affairs, Office of Thrift Supervision, Washington, DC 20552 for processing under Office regulations. Complaints... Opportunity Commission, Washington, DC 20506 and a copy, for information only, sent to the Director,...

  18. 29 CFR 1614.106 - Individual complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Individual complaints. 1614.106 Section 1614.106 Labor... EMPLOYMENT OPPORTUNITY Agency Program To Promote Equal Employment Opportunity § 1614.106 Individual... individual and the agency and to describe generally the action(s) or practice(s) that form the basis of...

  19. 12 CFR 268.105 - Individual complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Individual complaints. 268.105 Section 268.105... RULES REGARDING EQUAL OPPORTUNITY Board Program To Promote Equal Opportunity § 268.105 Individual... individual and the Board and to describe generally the action(s) or practice(s) that form the basis of...

  20. 78 FR 52868 - Pole Attachment Complaint Procedures

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-27

    ... regulations concerning pole attachments outlined in the DATES section. DATES: Effective August 27, 2013, the amendments to Sec. Sec. 1.1403(e) and 1.1404 published at 63 FR 12025, March 12, 1998,have been approved by... COMMISSION 47 CFR Part 1 Pole Attachment Complaint Procedures AGENCY: Federal Communications...

  1. 21 CFR 226.115 - Complaint files.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Complaint files. 226.115 Section 226.115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL... files. Records shall be maintained for a period of 2 years of all written or verbal...

  2. 43 CFR 4.450-4 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... acquisition of title to, or an interest, in such land: (4) A statement in clear and concise language of the... personal knowledge of the alleged fact and such fact must be set forth in the statement. All statements by... the contestee files an answer to the complaint in such office within 30 days after service of...

  3. 41 CFR 101-8.716 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Complaints. 101-8.716 Section 101-8.716 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 8-NONDISCRIMINATION IN PROGRAMS RECEIVING...

  4. 45 CFR 617.9 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION NONDISCRIMINATION ON THE BASIS... 180 days from the date the complainant first had knowledge of the alleged act of discrimination... complaint, any written statement which identifies the parties involved and the date the complainant...

  5. 45 CFR 617.9 - Complaints.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION NONDISCRIMINATION ON THE BASIS... 180 days from the date the complainant first had knowledge of the alleged act of discrimination... complaint, any written statement which identifies the parties involved and the date the complainant...

  6. 45 CFR 617.9 - Complaints.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION NONDISCRIMINATION ON THE BASIS... 180 days from the date the complainant first had knowledge of the alleged act of discrimination... complaint, any written statement which identifies the parties involved and the date the complainant...

  7. 40 CFR 7.120 - Complaint investigations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Complaint investigations. 7.120 Section 7.120 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL NONDISCRIMINATION IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL ASSISTANCE FROM THE ENVIRONMENTAL PROTECTION AGENCY...

  8. 40 CFR 7.120 - Complaint investigations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Complaint investigations. 7.120 Section 7.120 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL NONDISCRIMINATION IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL ASSISTANCE FROM THE ENVIRONMENTAL PROTECTION AGENCY...

  9. 40 CFR 7.120 - Complaint investigations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Complaint investigations. 7.120 Section 7.120 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL NONDISCRIMINATION IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL ASSISTANCE FROM THE ENVIRONMENTAL PROTECTION AGENCY...

  10. 29 CFR 29.12 - Complaints.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Agency may adopt a complaint review procedure differing in detail from that given in this section... provisions in 29 CFR part 30, or applicable provisions of a State Plan for Equal Employment Opportunity in Apprenticeship adopted pursuant to 29 CFR part 30 and approved by the Department. (b) Except for...

  11. 12 CFR 268.204 - Class complaints.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... discriminates against the group on the basis of their race, color, religion, sex, national origin, age or... judge may dismiss the complaint, or any portion, for any of the reasons listed in § 268.106 or because... hearing shall be conducted in accordance with 12 CFR 268.108(a) through (f). (i) Report of findings...

  12. How to File a Consumer Credit Complaint.

    ERIC Educational Resources Information Center

    Board of Governors of the Federal Reserve System, Washington, DC.

    Designed for the general public and possibly suitable also for high school economics students, this pamphlet explains how a complaint against a Federal Reserve bank concerning a possible violation of any of the federal consumer credit laws can be filed. Seven consumer credit laws are listed with a brief statement about the major protections of…

  13. 32 CFR 776.79 - The complaint.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 5 2013-07-01 2013-07-01 false The complaint. 776.79 Section 776.79 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY MISCELLANEOUS RULES PROFESSIONAL CONDUCT OF ATTORNEYS PRACTICING UNDER THE COGNIZANCE AND SUPERVISION OF THE JUDGE ADVOCATE GENERAL...

  14. 32 CFR 776.79 - The complaint.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 5 2014-07-01 2014-07-01 false The complaint. 776.79 Section 776.79 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY MISCELLANEOUS RULES PROFESSIONAL CONDUCT OF ATTORNEYS PRACTICING UNDER THE COGNIZANCE AND SUPERVISION OF THE JUDGE ADVOCATE GENERAL...

  15. 32 CFR 776.79 - The complaint.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false The complaint. 776.79 Section 776.79 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY MISCELLANEOUS RULES PROFESSIONAL CONDUCT OF ATTORNEYS PRACTICING UNDER THE COGNIZANCE AND SUPERVISION OF THE JUDGE ADVOCATE GENERAL...

  16. 21 CFR 211.198 - Complaint files.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... longer. In the case of certain OTC drug products lacking expiration dating because they meet the criteria... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Complaint files. 211.198 Section 211.198 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS:...

  17. 7 CFR 47.6 - Formal complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... original and three copies shall be furnished for filing, and service on the respondent. If there is more... determined by the examiner: Provided, That, if the amendment introduces a new or different cause of action...) fails to effect an amicable or informal settlement, the person who filed the informal complaint may,...

  18. SEA Complaint Management Procedures: A National Survey.

    ERIC Educational Resources Information Center

    South Atlantic Regional Resource Center, Plantation, FL.

    This report summarizes responses to a national survey of state education agencies (SEAs) concerning their complaint management procedures. Twenty-two states responded. Responses are summarized for each state to questions which addressed the following concerns: (1) the number of full-time equivalent (FTE) personnel responsible for implementing the…

  19. 21 CFR 1271.320 - Complaint file.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.320 Complaint file. (a) Procedures... as defined in § 1271.3(aa), relating to core current good tissue practice (CGTP) requirements,...

  20. 21 CFR 1271.320 - Complaint file.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.320 Complaint file. (a) Procedures... as defined in § 1271.3(aa), relating to core current good tissue practice (CGTP) requirements,...

  1. 21 CFR 1271.320 - Complaint file.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.320 Complaint file. (a) Procedures... as defined in § 1271.3(aa), relating to core current good tissue practice (CGTP) requirements,...

  2. 21 CFR 1271.320 - Complaint file.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS, TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.320 Complaint file. (a) Procedures... as defined in § 1271.3(aa), relating to core current good tissue practice (CGTP) requirements,...

  3. 21 CFR 211.198 - Complaint files.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Complaint files. 211.198 Section 211.198 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Records and Reports § 211.198...

  4. 21 CFR 211.198 - Complaint files.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Complaint files. 211.198 Section 211.198 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Records and Reports § 211.198...

  5. 21 CFR 211.198 - Complaint files.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Complaint files. 211.198 Section 211.198 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Records and Reports § 211.198...

  6. Student Complaints and Appeals: The Practitioner's View

    ERIC Educational Resources Information Center

    Buckton, Liz

    2008-01-01

    This article explores the issues facing practitioners working in the field of student complaints and appeals (including academic appeals). It is a reflective study which examines some general and historical issues, using anonymised case studies where appropriate and highlighting the diversity of practice across the sector. The author observes that…

  7. 40 CFR 7.120 - Complaint investigations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... recipients of Federal assistance (see 28 CFR part 42, subpart H and 29 CFR part 1691). Complainants are... discriminatory acts occurred. (1) The complaint must be in writing and it must describe the alleged... allegations and give the applicant or recipient opportunity to make a written submission responding...

  8. 45 CFR 704.2 - Complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Regulations Relating to Public Welfare (Continued) COMMISSION ON CIVIL RIGHTS INFORMATION DISCLOSURE AND.... This shall be done by submitting a complaint in writing to the Office of Civil Rights Evaluation, U.S. Commission on Civil Rights, 9th Street, NW., Washington, DC 20425. Allegations falling under section...

  9. 45 CFR 704.2 - Complaints.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Regulations Relating to Public Welfare (Continued) COMMISSION ON CIVIL RIGHTS INFORMATION DISCLOSURE AND.... This shall be done by submitting a complaint in writing to the Office of Civil Rights Evaluation, U.S. Commission on Civil Rights, 9th Street, NW., Washington, DC 20425. Allegations falling under section...

  10. 45 CFR 704.2 - Complaints.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Regulations Relating to Public Welfare (Continued) COMMISSION ON CIVIL RIGHTS INFORMATION DISCLOSURE AND.... This shall be done by submitting a complaint in writing to the Office of Civil Rights Evaluation, U.S. Commission on Civil Rights, 9th Street, NW., Washington, DC 20425. Allegations falling under section...

  11. 20 CFR 658.401 - Types of complaints handled by the JS complaint system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... mandatory listing requirements under 38 U.S.C. 2012 shall not be handled under this subpart. The State agency shall handle such complaints under the Department's regulations at 41 CFR part 60-250....

  12. Reproducibility of sterilized rubber impressions.

    PubMed

    Abdelaziz, Khalid M; Hassan, Ahmed M; Hodges, J S

    2004-01-01

    Impressions, dentures and other dental appliances may be contaminated with oral micro-flora or other organisms of varying pathogenicity from patient's saliva and blood. Several approaches have been tried to control the transmission of infectious organisms via dental impressions and because disinfection is less effective and has several drawbacks for impression characterization, several sterilization methods have been suggested. This study evaluated the reproducibility of rubber impressions after sterilization by different methods. Dimensional accuracy and wettability of two rubber impression materials (vinyl polysiloxane and polyether) were evaluated after sterilization by each of three well-known methods (immersion in 2% glutaraldehyde for 10 h, autoclaving and microwave radiation). Non-sterilized impressions served as control. The effect of the tray material on impression accuracy and the effect of topical surfactant on the wettability were also evaluated. One-way ANOVA with Dunnett's method was used for statistical analysis. All sterilizing methods reduced the reproducibility of rubber impressions, although not always significantly. Microwave sterilization had a small effect on both accuracy and wettability. The greater effects of the other methods could usually be overcome by using ceramic trays and by spraying impression surfaces with surfactant before pouring the gypsum mix. There was one exception: glutaraldehyde still degraded dimensional accuracy even with ceramic trays and surfactant. We conclude that a) sterilization of rubber impressions made on acrylic trays was usually associated with a degree of dimensional change; b) microwave energy seems to be a suitable technique for sterilizing rubber impressions; c) topical surfactant application helped restore wettability of sterilized impressions. PMID:15798825

  13. Evaluation of guidewire path reproducibility.

    PubMed

    Schafer, Sebastian; Hoffmann, Kenneth R; Noël, Peter B; Ionita, Ciprian N; Dmochowski, Jacek

    2008-05-01

    The number of minimally invasive vascular interventions is increasing. In these interventions, a variety of devices are directed to and placed at the site of intervention. The device used in almost all of these interventions is the guidewire, acting as a monorail for all devices which are delivered to the intervention site. However, even with the guidewire in place, clinicians still experience difficulties during the interventions. As a first step toward understanding these difficulties and facilitating guidewire and device guidance, we have investigated the reproducibility of the final paths of the guidewire in vessel phantom models on different factors: user, materials and geometry. Three vessel phantoms (vessel diameters approximately 4 mm) were constructed having tortuousity similar to the internal carotid artery from silicon tubing and encased in Sylgard elastomer. Several trained users repeatedly passed two guidewires of different flexibility through the phantoms under pulsatile flow conditions. After the guidewire had been placed, rotational c-arm image sequences were acquired (9 in. II mode, 0.185 mm pixel size), and the phantom and guidewire were reconstructed (512(3), 0.288 mm voxel size). The reconstructed volumes were aligned. The centerlines of the guidewire and the phantom vessel were then determined using region-growing techniques. Guidewire paths appear similar across users but not across materials. The average root mean square difference of the repeated placement was 0.17 +/- 0.02 mm (plastic-coated guidewire), 0.73 +/- 0.55 mm (steel guidewire) and 1.15 +/- 0.65 mm (steel versus plastic-coated). For a given guidewire, these results indicate that the guidewire path is relatively reproducible in shape and position.

  14. Psychosocial Working Conditions and Cognitive Complaints among Swedish Employees

    PubMed Central

    Stenfors, Cecilia U. D.; Magnusson Hanson, Linda; Oxenstierna, Gabriel; Theorell, Töres; Nilsson, Lars-Göran

    2013-01-01

    Background Cognitive complaints involving problems with concentration, memory, decision-making and thinking are relatively common in the work force. The sensitivity of both subjective and objective cognitive functioning to common psychiatric conditions, stress levels and to cognitive load makes it plausible that psychosocial working conditions play a role in cognitive complaints. Thus, this study aimed to test the associations between psychosocial work factors and cognitive complaints in nationally representative samples of the Swedish work force. Cross-sectional (n = 9751) and prospective (n = 3644; two time points two years apart) sequential multiple regression analyses were run, adjusting for general confounders, depressive- and sleeping problems. Additional prospective analyses were run adjusting for baseline cognitive complaints. Cross-sectional results High quantitative demands, information and communication technology (ICT) demands, underqualification and conflicts were positively associated with cognitive complaints, while social support, good resources at work and overqualification were negatively associated with cognitive complaints in all models. Skill discretion and decision authority were weakly associated with cognitive complaints. Conflicts were more strongly associated with cognitive complaints in women than in men, after adjustment for general confounders. Prospective results Quantitative job demands, ICT demands and underqualification were positively associated with future cognitive complaints in all models, including when adjusted for baseline cognitive complaints. Decision authority was weakly positively associated with future cognitive complaints, only after adjustment for depressive- and sleeping problems respectively. Social support was negatively associated with future cognitive complaints after adjustment for general confounders and baseline cognitive complaints. Skill discretion and resources were negatively associated with future

  15. 29 CFR 42.7 - Complaint/directed action logs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Complaint/directed action logs. 42.7 Section 42.7 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.7 Complaint/directed action logs. (a) To... operation of a system of coordinated Complaint/Directed Action Logs (logs). The logs shall be maintained...

  16. 32 CFR 1900.04 - Suggestions and complaints.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....04 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY PUBLIC... complaints. The Agency welcomes suggestions or complaints with regard to its administration of the Freedom of... suggestion or complaint should identify the specific purpose and the issues for consideration. The...

  17. 32 CFR 1900.04 - Suggestions and complaints.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....04 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY PUBLIC... complaints. The Agency welcomes suggestions or complaints with regard to its administration of the Freedom of... suggestion or complaint should identify the specific purpose and the issues for consideration. The...

  18. 32 CFR 1900.04 - Suggestions and complaints.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....04 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY PUBLIC... complaints. The Agency welcomes suggestions or complaints with regard to its administration of the Freedom of... suggestion or complaint should identify the specific purpose and the issues for consideration. The...

  19. 32 CFR 1900.04 - Suggestions and complaints.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....04 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY PUBLIC... complaints. The Agency welcomes suggestions or complaints with regard to its administration of the Freedom of... suggestion or complaint should identify the specific purpose and the issues for consideration. The...

  20. 40 CFR 135.4 - Service of complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... citizen plaintiff shall mail a copy of a complaint filed against an alleged violator under section 505(a..., accompanied by a signed statement by the plaintiff or his attorney as to when the complaint was filed. (c) A citizen plaintiff shall mail a copy of the complaint on the same date on which the plaintiff files...

  1. 28 CFR 35.172 - Resolution of complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Resolution of complaints. 35.172 Section... STATE AND LOCAL GOVERNMENT SERVICES Compliance Procedures § 35.172 Resolution of complaints. (a) The designated agency shall investigate each complete complaint, attempt informal resolution, and, if...

  2. 29 CFR 1603.103 - Referral of complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE GOVERNMENT EMPLOYEE RIGHTS ACT OF 1991 Administrative Process § 1603.103 Referral of complaints. (a) The Commission will notify an FEP agency, as defined in 29 CFR 1601.3(a), when a complaint...

  3. 47 CFR 8.14 - General formal complaint procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false General formal complaint procedures. 8.14 Section 8.14 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.14 General formal complaint procedures. (a) Complaints. In addition to the general...

  4. 47 CFR 8.14 - General formal complaint procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false General formal complaint procedures. 8.14 Section 8.14 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.14 General formal complaint procedures. (a) Complaints. In addition to the general...

  5. 47 CFR 8.14 - General formal complaint procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false General formal complaint procedures. 8.14 Section 8.14 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.14 General formal complaint procedures. (a) Complaints. In addition to the general...

  6. 47 CFR 8.14 - General formal complaint procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false General formal complaint procedures. 8.14 Section 8.14 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRESERVING THE OPEN INTERNET § 8.14 General formal complaint procedures. (a) Complaints. In addition to the general...

  7. 10 CFR 13.8 - Service of complaint.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Service of complaint. 13.8 Section 13.8 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.8 Service of complaint. (a) Service of a complaint must be made by certified or registered mail or by delivery in any manner authorized by Rule 4(d)...

  8. 10 CFR 13.6 - Prerequisities for issuing a complaint.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Prerequisities for issuing a complaint. 13.6 Section 13.6 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.6 Prerequisities for issuing a complaint. (a) The reviewing official may issue a complaint under § 13.7 only if— (1) The Department...

  9. 7 CFR 18.5 - Formal complaint procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... formal written complaint if a complainant is not satisfied with the result of informal procedure or if the complainant does not desire to follow the informal procedure. A complaint procedure shall contain... organization may file a complaint of general discriminatory practices: Provided, however, That upon request...

  10. 76 FR 76628 - Disclosure of Certain Credit Card Complaint Data

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-08

    ... knowledge and belief. The system will accept complaints submitted on behalf of a consumer. These complaints... Bureau has received and collected in its central database on complaints during the preceding year.'' 12 U... treatment of confidential information. See 76 FR 45372 (July 28, 2011) (to be codified at 12 CFR Part...

  11. 78 FR 21218 - Disclosure of Consumer Complaint Data

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... Student Loan Ombudsman (October 16, 2012) at http://files.consumerfinance.gov/f/201210_cfpb_Student-Loan... complaints. Complaint data on bank accounts and services, private student loans, and other consumer loans... request for comment), 76 FR 76628 (Dec. 8, 2011) (Proposed Credit Card Complaint Data Disclosure...

  12. 48 CFR 203.904 - Procedures for filing complaints.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... complaints. 203.904 Section 203.904 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Whistleblower Protections for Contractor Employees 203.904 Procedures for filing complaints. In addition to the... otherwise discriminated against contrary to the policy in 203.903 may file a complaint with the...

  13. Stress and Somatic Complaints in Low-Income Urban Adolescents.

    ERIC Educational Resources Information Center

    Reynolds, Linda K.; O'Koon, Jeffrey H.; Papademetriou, Eros; Szczygiel, Sylvia; Grant, Kathryn E.

    2001-01-01

    Studied rates of somatic complaints and the association between stress and somatic complaints for 1,030 low-income urban adolescents in grades 6 through 8. For both boys and girls, somatization was the most commonly reported internalizing symptom, and heightened rates of urban stress predicted heightened rates of somatic complaints. (SLD)

  14. 6 CFR 13.8 - Service of Complaint.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Service of Complaint. 13.8 Section 13.8 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.8 Service of Complaint. (a) Service of a Complaint must be Made by certified or registered mail or...

  15. 6 CFR 13.6 - Prerequisites for issuing a Complaint.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Prerequisites for issuing a Complaint. 13.6 Section 13.6 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD... Complaint under § 13.7 only if: (1) The Department of Justice approves the issuance of a Complaint in...

  16. 6 CFR 13.6 - Prerequisites for issuing a Complaint.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Prerequisites for issuing a Complaint. 13.6 Section 13.6 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD... Complaint under § 13.7 only if: (1) The Department of Justice approves the issuance of a Complaint in...

  17. 6 CFR 13.8 - Service of Complaint.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Service of Complaint. 13.8 Section 13.8 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.8 Service of Complaint. (a) Service of a Complaint must be Made by certified or registered mail or...

  18. 41 CFR 60-250.61 - Complaint procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SPECIAL DISABLED VETERANS, VETERANS OF THE VIETNAM ERA, RECENTLY SEPARATED VETERANS, AND OTHER PROTECTED VETERANS General Enforcement and Complaint Procedures § 60-250.61 Complaint procedures. (a) Place and time... complaint must be filed within 300 days of the date of the alleged violation, unless the time for filing...

  19. 41 CFR 60-300.61 - Complaint procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... DISABLED VETERANS, RECENTLY SEPARATED VETERANS, OTHER PROTECTED VETERANS, AND ARMED FORCES SERVICE MEDAL VETERANS General Enforcement and Complaint Procedures § 60-300.61 Complaint procedures. (a) Place and time... complaint must be filed within 300 days of the date of the alleged violation, unless the time for filing...

  20. 7 CFR 1924.259 - Handling dwelling construction complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... defects will be requested to make a written complaint using a format specified by FmHA or its successor agency under Public Law 103-354 (available in any FmHA or its successor agency under Public Law 103-354... complaint will impose a hardship on the borrower. If an oral complaint is made, FmHA or its successor...

  1. 7 CFR 1924.259 - Handling dwelling construction complaints.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... defects will be requested to make a written complaint using a format specified by FmHA or its successor agency under Public Law 103-354 (available in any FmHA or its successor agency under Public Law 103-354... complaint will impose a hardship on the borrower. If an oral complaint is made, FmHA or its successor...

  2. 7 CFR 1924.259 - Handling dwelling construction complaints.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... defects will be requested to make a written complaint using a format specified by FmHA or its successor agency under Public Law 103-354 (available in any FmHA or its successor agency under Public Law 103-354... complaint will impose a hardship on the borrower. If an oral complaint is made, FmHA or its successor...

  3. 32 CFR 112.5 - Processing of debt complaints.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Processing of debt complaints. 112.5 Section 112... CIVILIAN INDEBTEDNESS OF MILITARY PERSONNEL § 112.5 Processing of debt complaints. (a) Debt complaints... made a bona fide effort to collect the debt directly from the military member; (2) Whose claims...

  4. 32 CFR 112.5 - Processing of debt complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Processing of debt complaints. 112.5 Section 112... CIVILIAN INDEBTEDNESS OF MILITARY PERSONNEL § 112.5 Processing of debt complaints. (a) Debt complaints... made a bona fide effort to collect the debt directly from the military member; (2) Whose claims...

  5. 39 CFR 3030.2 - Scope and nature of complaints.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Scope and nature of complaints. 3030.2 Section 3030.2 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES FOR COMPLAINTS General § 3030.2 Scope and nature of complaints. Any interested person (including a duly appointed officer of...

  6. 39 CFR 3030.2 - Scope and nature of complaints.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Scope and nature of complaints. 3030.2 Section 3030.2 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES FOR COMPLAINTS General § 3030.2 Scope and nature of complaints. Any interested person (including a duly appointed officer of...

  7. 39 CFR 3030.2 - Scope and nature of complaints.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Scope and nature of complaints. 3030.2 Section 3030.2 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES FOR COMPLAINTS General § 3030.2 Scope and nature of complaints. Any interested person (including a duly appointed officer of...

  8. 39 CFR 3030.2 - Scope and nature of complaints.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Scope and nature of complaints. 3030.2 Section 3030.2 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES FOR COMPLAINTS General § 3030.2 Scope and nature of complaints. Any interested person (including a duly appointed officer of...

  9. Complaint Handling in the Library. Occasional Papers Number 166.

    ERIC Educational Resources Information Center

    Robinson, William C.

    Arguing that complaints are inevitable and that complaint handling should be an integral part of the library's public service program, this paper identifies and discusses the components of such a program. Concerns discussed are those that should be of general interest to all types of libraries, and the primary focus is on external complaints,…

  10. 20 CFR 901.35 - Contents of complaint.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Contents of complaint. 901.35 Section 901.35 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES REGULATIONS GOVERNING THE PERFORMANCE OF... Enrollment § 901.35 Contents of complaint. (a) Charges. A complaint initiating a suspension or...

  11. 77 FR 47820 - Invention Promoters/Promotion Firms Complaints

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-10

    ... United States Patent and Trademark Office Invention Promoters/Promotion Firms Complaints ACTION: Proposed... concerning invention promoters and responses from the invention promoters to these complaints. An individual may submit a complaint concerning an invention promoter to the USPTO, which will forward the...

  12. 39 CFR 3031.12 - Treatment as a complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Treatment as a complaint. 3031.12 Section 3031.12... Inquiry Forms and Procedures § 3031.12 Treatment as a complaint. If the Commission receives a volume of... treatment as a complaint, it may appoint an investigator to review the matter under § 3030.21 of...

  13. 39 CFR 3031.12 - Treatment as a complaint.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Treatment as a complaint. 3031.12 Section 3031.12... Inquiry Forms and Procedures § 3031.12 Treatment as a complaint. If the Commission receives a volume of... treatment as a complaint, it may appoint an investigator to review the matter under § 3030.21 of...

  14. 14 CFR 302.507 - Computing time for filing complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Computing time for filing complaints. 302... Proceedings With Respect to Rates, Fares and Charges for Foreign Air Transportation § 302.507 Computing time for filing complaints. In computing the time for filing formal complaints pursuant to § 302.506,...

  15. 29 CFR 1603.102 - Filing a complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... THE GOVERNMENT EMPLOYEE RIGHTS ACT OF 1991 Administrative Process § 1603.102 Filing a complaint. (a... appear in 29 CFR 1610.4. (c) Contents of a complaint. A complaint shall be in writing, signed and... alleged unlawful employment practices (See 29 CFR 1601.15(b)); and (4) A statement disclosing...

  16. 39 CFR 3031.12 - Treatment as a complaint.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Treatment as a complaint. 3031.12 Section 3031.12... Inquiry Forms and Procedures § 3031.12 Treatment as a complaint. If the Commission receives a volume of... treatment as a complaint, it may appoint an investigator to review the matter under § 3030.21 of...

  17. 39 CFR 3031.12 - Treatment as a complaint.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Treatment as a complaint. 3031.12 Section 3031.12... Inquiry Forms and Procedures § 3031.12 Treatment as a complaint. If the Commission receives a volume of... treatment as a complaint, it may appoint an investigator to review the matter under § 3030.21 of...

  18. 39 CFR 3031.12 - Treatment as a complaint.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Treatment as a complaint. 3031.12 Section 3031.12... Inquiry Forms and Procedures § 3031.12 Treatment as a complaint. If the Commission receives a volume of... treatment as a complaint, it may appoint an investigator to review the matter under § 3030.21 of...

  19. 77 FR 37616 - Disclosure of Consumer Complaint Data

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... OF CONSUMER FINANCIAL PROTECTION 12 CFR Chapter X Disclosure of Consumer Complaint Data AGENCY... statement regarding the Bureau's disclosure of data from consumer complaints about financial products and... complaint data. The present notice (the ``Concurrent Notice'') describes the Bureau's plan to duplicate...

  20. 29 CFR 42.7 - Complaint/directed action logs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Complaint/directed action logs. 42.7 Section 42.7 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.7 Complaint/directed action logs. (a) To... operation of a system of coordinated Complaint/Directed Action Logs (logs). The logs shall be maintained...

  1. 29 CFR 42.7 - Complaint/directed action logs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Complaint/directed action logs. 42.7 Section 42.7 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.7 Complaint/directed action logs. (a) To... operation of a system of coordinated Complaint/Directed Action Logs (logs). The logs shall be maintained...

  2. 29 CFR 42.7 - Complaint/directed action logs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Complaint/directed action logs. 42.7 Section 42.7 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.7 Complaint/directed action logs. (a) To... operation of a system of coordinated Complaint/Directed Action Logs (logs). The logs shall be maintained...

  3. 29 CFR 42.7 - Complaint/directed action logs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Complaint/directed action logs. 42.7 Section 42.7 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.7 Complaint/directed action logs. (a) To... operation of a system of coordinated Complaint/Directed Action Logs (logs). The logs shall be maintained...

  4. 40 CFR 374.5 - Copy of complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Copy of complaint. 374.5 Section 374.5... COMMUNITY RIGHT-TO-KNOW PROGRAMS PRIOR NOTICE OF CITIZEN SUITS § 374.5 Copy of complaint. At the time of filing an action under this Act, the plaintiff must provide a copy of the complaint to the...

  5. 5 CFR 1201.130 - Rights; answer to complaint.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Rights; answer to complaint. 1201.130... § 1201.130 Rights; answer to complaint. (a) Rights. (1) A person on whose behalf the Special Counsel...) When the Special Counsel files a complaint seeking corrective action, the judge to whom the...

  6. 41 CFR 60-300.61 - Complaint procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Complaint procedures. 60-300.61 Section 60-300.61 Public Contracts and Property Management Other Provisions Relating to Public... VETERANS General Enforcement and Complaint Procedures § 60-300.61 Complaint procedures. (a) Place and...

  7. 41 CFR 60-741.61 - Complaint procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Complaint procedures. 60-741.61 Section 60-741.61 Public Contracts and Property Management Other Provisions Relating to Public... INDIVIDUALS WITH DISABILITIES General Enforcement and Complaint Procedures § 60-741.61 Complaint...

  8. 41 CFR 60-250.61 - Complaint procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Complaint procedures. 60-250.61 Section 60-250.61 Public Contracts and Property Management Other Provisions Relating to Public... VETERANS General Enforcement and Complaint Procedures § 60-250.61 Complaint procedures. (a) Place and...

  9. 21 CFR 1402.7 - Suggestions and complaints.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Suggestions and complaints. 1402.7 Section 1402.7 Food and Drugs OFFICE OF NATIONAL DRUG CONTROL POLICY MANDATORY DECLASSIFICATION REVIEW § 1402.7 Suggestions and complaints. Suggestions and complaints regarding the information security program of...

  10. 21 CFR 1402.7 - Suggestions and complaints.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Suggestions and complaints. 1402.7 Section 1402.7 Food and Drugs OFFICE OF NATIONAL DRUG CONTROL POLICY MANDATORY DECLASSIFICATION REVIEW § 1402.7 Suggestions and complaints. Suggestions and complaints regarding the information security program of...

  11. 21 CFR 1402.7 - Suggestions and complaints.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Suggestions and complaints. 1402.7 Section 1402.7 Food and Drugs OFFICE OF NATIONAL DRUG CONTROL POLICY MANDATORY DECLASSIFICATION REVIEW § 1402.7 Suggestions and complaints. Suggestions and complaints regarding the information security program of...

  12. 29 CFR 2700.42 - Contents of complaint.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false Contents of complaint. 2700.42 Section 2700.42 Labor Regulations Relating to Labor (Continued) FEDERAL MINE SAFETY AND HEALTH REVIEW COMMISSION PROCEDURAL RULES Complaints of Discharge, Discrimination or Interference § 2700.42 Contents of complaint. A...

  13. 10 CFR 708.3 - What employee complaints are covered?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false What employee complaints are covered? 708.3 Section 708.3 Energy DEPARTMENT OF ENERGY DOE CONTRACTOR EMPLOYEE PROTECTION PROGRAM General Provisions § 708.3 What employee complaints are covered? This part applies to a complaint of retaliation filed by an employee of...

  14. 10 CFR 708.3 - What employee complaints are covered?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false What employee complaints are covered? 708.3 Section 708.3 Energy DEPARTMENT OF ENERGY DOE CONTRACTOR EMPLOYEE PROTECTION PROGRAM General Provisions § 708.3 What employee complaints are covered? This part applies to a complaint of retaliation filed by an employee of...

  15. 39 CFR 3030.2 - Scope and nature of complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Scope and nature of complaints. 3030.2 Section 3030.2 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL RULES FOR COMPLAINTS General § 3030.2 Scope and nature of complaints. Any interested person (including a duly appointed officer of...

  16. 49 CFR 1111.1 - Content of formal complaints; joinder.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Content of formal complaints; joinder. 1111.1... § 1111.1 Content of formal complaints; joinder. (a) General. A formal complaint must contain the correct... language the facts upon which it is based. It should include specific reference to pertinent...

  17. 20 CFR 655.1005 - Complaints and investigative procedures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Attestations Filed by Employers Utilizing F-1 Students in Off-Campus Work § 655.1005 Complaints and... and Hour Division official who receives the complaint. The complaint shall set forth sufficient facts... any local Wage and Hour Division office, the addresses of which can be found in local...

  18. [Zinc and gastrointestinal disorders].

    PubMed

    Higashimura, Yasuki; Takagi, Tomohisa; Naito, Yuji

    2016-07-01

    Zinc, an essential trace element, affects immune responses, skin metabolism, hormone composition, and some sensory function, so that the deficiency presents various symptoms such as immunodeficiency and taste obstacle. Further, the zinc deficiency also considers as a risk of various diseases. Recent reports demonstrated that -20% of the Japanese population was marginally zinc deficiency, and over 25% of the global population is at high risk of zinc deficiency. In gastrointestinal disorders, zinc plays an important role in the healing of mucosal and epithelial damage. In fact, polaprezinc, a chelate compound of zinc and L-carnosine, has been used for the treatment of gastric ulcer and gastritis. We describe here the therapeutic effect of zinc on gastrointestinal disorders. PMID:27455800

  19. [Microbiota and gastrointestinal diseases].

    PubMed

    Polanco Allué, I

    2015-12-01

    The bacterial colonisation is established immediately after birth, through direct contact with maternal microbiota, and may be influenced during lactation. There is emerging evidence indicating that quantitative and qualitative changes on gut microbiota contribute to alterations in the mucosal activation of the immune system, leading to intra- or extra-intestinal diseases. A balance between pathogenic and beneficial microbiota throughout childhood and adolescence is important to gastrointestinal health, including protection against pathogens, inhibition of pathogens, nutrient processing (synthesis of vitamin K), stimulation of angiogenesis, and regulation of host fat storage. Probiotics can promote an intentional modulation of intestinal microbiota favouring the health of the host. A review is presented on the modulation of intestinal microbiota on prevention, and adjuvant treatment of some paediatric gastrointestinal diseases. PMID:26534880

  20. Gastrointestinal stromal tumor

    PubMed Central

    Yue, Changjun

    2012-01-01

    Gastrointestinal stromal tumor has received a lot of attention over the last 10 years due to its unique biologic behavior, clinicopathological features, molecular mechanisms, and treatment implications. GIST is the most common mesenchymal neoplasm in the gastrointestinal tract and has emerged from a poorly understood and treatment resistant neoplasm to a well-defined tumor entity since the discovery of particular molecular abnormalities, KIT and PDGFRA gene mutations. The understanding of GIST biology at the molecular level promised the development of novel treatment modalities. Diagnosis of GIST depends on the integrity of histology, immunohistochemistry and molecular analysis. The risk assessment of the tumor behavior relies heavily on pathological evaluation and significantly impacts clinical management. In this review, historic review, epidemiology, pathogenesis and genetics, diagnosis, role of molecular analysis, prognostic factor and treatment strategies have been discussed. PMID:22943011

  1. Cefoperazone Induced Gastrointestinal Bleeding.

    PubMed

    Katukuri, Goutham Reddy; Maddala, Raja Naga Mahesh; Ramamoorthi, Kusugodlu; Hande, Manjunatha

    2016-08-01

    Cefoperazone is a beta-lactam antibiotic which is frequently used in treating a variety of gram positive and gram negative infections. The chemical structure of cefoperazone contains a side chain of N-methylthiotetrazole which can inhibit vitamin K metabolism resulting in hypoprothombinemia. We report a case of cefoperazone induced coagulopathy manifesting as gastrointestinal bleeding. A Naranjo assessment score of 5 was obtained, indicating a probable relationship between the patient's coagulation function disorder and her use of the suspect drug. PMID:27656491

  2. Gastrointestinal food allergies.

    PubMed

    Heine, Ralf G

    2015-01-01

    Gastrointestinal food allergies present during early childhood with a diverse range of symptoms. Cow's milk, soy and wheat are the three most common gastrointestinal food allergens. Several clinical syndromes have been described, including food protein-induced enteropathy, proctocolitis and enterocolitis. In contrast with immediate, IgE-mediated food allergies, the onset of gastrointestinal symptoms is delayed for at least 1-2 hours after ingestion in non-IgE-mediated allergic disorders. The pathophysiology of these non-IgE-mediated allergic disorders is poorly understood, and useful in vitro markers are lacking. The results of the skin prick test or measurement of the food-specific serum IgE level is generally negative, although low-positive results may occur. Diagnosis therefore relies on the recognition of a particular clinical phenotype as well as the demonstration of clear clinical improvement after food allergen elimination and the re-emergence of symptoms upon challenge. There is a significant clinical overlap between non-IgE-mediated food allergy and several common paediatric gastroenterological conditions, which may lead to diagnostic confusion. The treatment of gastrointestinal food allergies requires the strict elimination of offending food allergens until tolerance has developed. In breast-fed infants, a maternal elimination diet is often sufficient to control symptoms. In formula-fed infants, treatment usually involves the use an extensively hydrolysed or amino acid-based formula. Apart from the use of hypoallergenic formulae, the solid diets of these children also need to be kept free of specific food allergens, as clinically indicated. The nutritional progress of infants and young children should be carefully monitored, and they should undergo ongoing, regular food protein elimination reassessments by cautious food challenges to monitor for possible tolerance development.

  3. NSAIDS and gastrointestinal cancer.

    PubMed

    Piazuelo, Elena; Lanas, Angel

    2015-07-01

    A large body of evidence from epidemiological and preclinical studies have shown that nonsteroideal anti-inflammatory drugs (NSAIDs) have a chemopreventive effect on gastrointestinal cancers and, more specifically, in colorectal cancer. This review highlights recent advances in our understanding of the role of NSAIDs in colorectal cancer prevention and adjuvant treatment. Moreover, we have focused on randomized controlled studies assessing their efficacy to prevent adenoma recurrence and reduction of colorectal cancer incidence and mortality but also their gastrointestinal and cardiovascular side effects. Among NSAIDs, almost the unique agent with potential use as chemopreventive agent is aspirin at low dose since it has both no cardiovascular and low gastrointestinal risk. Furthermore, since aspirin has shown efficacy in secondary prevention of cardiovascular diseases, this drug carries a particular attractive intervention for selected populations. Nevertheless, before it can be prescribed, further studies are necessary to define some important questions, specially the most appropriate dose and time of aspirin use and the population who may benefit from it. PMID:26093284

  4. Psychosocial functioning in children and adolescents with gastrointestinal complaints and disorders.

    PubMed

    Hommel, Kevin A; McGraw, Kelly L; Ammerman, Robert T; Heubi, James E; Hansen, Molly; Dunlap, Ellen; Beidel, Deborah C

    2010-06-01

    The current study examined the prevalence and presentation of psychosocial symptoms in pediatric patients and their parents presenting for first time appointments at a gastroenterology (GI) clinic compared to healthy controls (HC). One hundred GI patients, aged 8-17 years, and their mothers were compared to 100 age- and gender-matched HC on measures of child and parental behavioral/psychosocial functioning, depression, and anxiety. Results revealed significant correlations between mother- and child-reported internalizing behaviors and psychological symptoms. Significant group differences were observed in internalizing problems, adaptive and social skills, and leadership competency, as well as parental interpersonal sensitivity, depression, phobic anxiety, and number of psychological symptoms. GI patients are at increased risk for psychosocial and social dysfunction compared to healthy peers. Psychosocial factors should be considered when assessing patients in GI clinics. Patients might benefit from treatment plans that involve adjunctive behavioral intervention to assist patients in managing their conditions. PMID:20372996

  5. Porcine survival model to simulate acute upper gastrointestinal bleedings.

    PubMed

    Prosst, Ruediger L; Schurr, Marc O; Schostek, Sebastian; Krautwald, Martina; Gottwald, Thomas

    2016-06-01

    The existing animal models used for the simulation of acute gastrointestinal bleedings are usually non-survival models. We developed and evaluated a new porcine model (domestic pig, German Landrace) in which the animal remains alive and survives the artificial bleeding without any cardiovascular impairment. This consists of a bleeding catheter which is implanted into the stomach, then subcutaneously tunnelled from the abdomen to the neck where it is exteriorized and fixed with sutures. Using the injection of porcine blood, controllable and reproducible acute upper gastrointestinal bleeding can be simulated while maintaining normal gastrointestinal motility and physiology. Depending on the volume of blood applied through the gastric catheter, the bleeding intensity can be varied from traces of blood to a massive haemorrhage. This porcine model could be valuable, e.g. for testing the efficacy of new bleeding diagnostics in large animals before human use. PMID:26306615

  6. Porcine survival model to simulate acute upper gastrointestinal bleedings.

    PubMed

    Prosst, Ruediger L; Schurr, Marc O; Schostek, Sebastian; Krautwald, Martina; Gottwald, Thomas

    2016-06-01

    The existing animal models used for the simulation of acute gastrointestinal bleedings are usually non-survival models. We developed and evaluated a new porcine model (domestic pig, German Landrace) in which the animal remains alive and survives the artificial bleeding without any cardiovascular impairment. This consists of a bleeding catheter which is implanted into the stomach, then subcutaneously tunnelled from the abdomen to the neck where it is exteriorized and fixed with sutures. Using the injection of porcine blood, controllable and reproducible acute upper gastrointestinal bleeding can be simulated while maintaining normal gastrointestinal motility and physiology. Depending on the volume of blood applied through the gastric catheter, the bleeding intensity can be varied from traces of blood to a massive haemorrhage. This porcine model could be valuable, e.g. for testing the efficacy of new bleeding diagnostics in large animals before human use.

  7. [Pre- and postoperative complaints in women with total hysterectomy].

    PubMed

    Rha, J G; Lee, J H

    1973-01-01

    A study was conducted at St. Mary's Hospital in Seoul, Korea, to determine levels of complaints before and after total hysterectomy. 113 women who underwent the operation from January 1968 to June 1972 were questioned as to medical, mental, and sexual complaints both pre- and postoperative. The total number of complaints decreased from 35.2% before to 30.2% after the operation. Each category of complaint decreased following the operation. Pelvic inflammatory disease and myom ata complaint rates decreased significantly. High rates of depression were common following the operation. PMID:12307215

  8. [Relationship between cigarette smoking and physical complaints].

    PubMed

    Kunugita, N; Norimura, T; Tsuchiya, T

    1993-06-01

    In order to evaluate the influence of cigarette smoking on health conditions, the authors analyzed results of the THI (Todai Health Index) questionnaire, which was administered to male employees of a large-sized enterprise in Osaka between 1984 and 1990. The smoking rate of male employees decreased over this period of time from 62.4% (1984) to 58.3% (1990) in this enterprise. Complaints regarding "respiratory organ", "digestive organ", "circulatory organ", "irregularity of daily life", "impulsiveness", and "many subjective symptoms" significantly increased with the amount of smoking. Many items of physical complaints in the THI questionnaire were also associated with smoking. These were coughing, sore throat, sputum, nausea when brushing teeth, loss of appetite, stomach pain, stomach problems, diarrhea, heartburn, gum problems, bad breath, heavy eyelids, itchy skin, face looked pale, shortness of breath, palpitation, feeling flushed or feverish, back pain, going to bed late and getting up late, weakness or fatigue, irregular meals, irritation, sensitive or nervous, eating salty or greasy food, and heavy drinker. It is therefore important in the health education of individual smokers to put special emphasis not only on the many diseases associated with smoking but also these physical complaints. PMID:8316711

  9. Sensitization, subjective health complaints, and sustained arousal.

    PubMed

    Ursin, H; Eriksen, H R

    2001-03-01

    The purpose of this presentation is to discuss the possibility that sensitization is a psychobiological mechanism underlying not only multiple chemical sensitivity (MCS), but a much more general cluster of illness, referred to as "subjective health complaints". Sustained arousal, or sustained "stress" responses, may be an important factor for the development of these conditions. Patients with subjective complaints without objective changes are sometimes referred to as having "fashionable diagnoses" or "unexplained symptoms". They may be given diagnoses like MCS, epidemic fatigue, chronic fatigue syndrome, burnout, stress, a variety of intoxications, environmental illness, radiation, multiple chemical hypersensitivity, food intolerance, functional dyspepsia, irritable bowel, myalgic encephalitis, postviral syndrome, yuppie flu, fibromyalgia, or vital exhaustion. One issue is whether this is one general condition or separate entities. Another issue is whether sensitization may be the psychobiological mechanism for most or all of these conditions. Finally, is it likely that sustained arousal may facilitate the development of sensitization in some or many neural circuits? In this review, the main emphasis will be on musculoskeletal pain. This is the most frequent and most expensive condition for sickness compensation and disability. The comorbidity of other complaints, however, will also be taken into account.

  10. 20 CFR 901.36 - Service of complaint and other papers.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Service of complaint and other papers. 901.36... Termination of Enrollment § 901.36 Service of complaint and other papers. (a) Complaint. The complaint or a... papers other than complaint. Any paper other than the complaint may be served upon the respondent...

  11. 20 CFR 901.36 - Service of complaint and other papers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Service of complaint and other papers. 901.36... Termination of Enrollment § 901.36 Service of complaint and other papers. (a) Complaint. The complaint or a... papers other than complaint. Any paper other than the complaint may be served upon the respondent...

  12. 20 CFR 901.36 - Service of complaint and other papers.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Service of complaint and other papers. 901.36... Termination of Enrollment § 901.36 Service of complaint and other papers. (a) Complaint. The complaint or a... papers other than complaint. Any paper other than the complaint may be served upon the respondent...

  13. 20 CFR 901.36 - Service of complaint and other papers.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Service of complaint and other papers. 901.36... Termination of Enrollment § 901.36 Service of complaint and other papers. (a) Complaint. The complaint or a... papers other than complaint. Any paper other than the complaint may be served upon the respondent...

  14. Gastrointestinal problems in modern wars: clinical features and possible mechanisms.

    PubMed

    Wang, Wei-Feng; Guo, Xiao-Xu; Yang, Yun-Sheng

    2015-01-01

    Gastrointestinal problems are common during wars, and they have exerted significant adverse effects on the health of service members involved in warfare. The spectrum of digestive diseases has varied during wars of different eras. At the end of the 20th century, new frontiers of military medical research emerged due to the occurrence of high-tech wars such as the Gulf War and the Kosovo War, in which ground combat was no longer the primary method of field operations. The risk to the military personnel who face trauma has been greatly reduced, but disease and non-battle injuries (DNBIs) such as neuropsychological disorders and digestive diseases seemed to be increased. Data revealed that gastrointestinal symptoms such as constipation, diarrhea, dyspepsia, and noncardiac chest pain are common among military personnel during modern wars. In addition, a large number of deployed soldiers and veterans who participated in recent wars presented with chronic gastrointestinal complaints, which fulfilled with the Rome III criteria for functional gastrointestinal disorders (FGIDs). It was also noted that many veterans who returned from the Gulf War suffered not only from chronic digestive symptoms but also from neuropsychological dysfunction; however, they also showed symptoms of other systems. Presently, this broad range of unexplained symptoms is known as "Gulf War syndrome". The mechanism that underlies Gulf War syndrome remains unclear, but many factors have been associated with this syndrome such as war trauma, stress, infections, immune dysfunction, radiological factors, anthrax vaccination and so on. Some have questioned if the diagnosis of FGIDs can be reached given the complexity of the military situation. As a result, further studies are needed to elucidate the pathogenesis of gastrointestinal disease among military personnel.

  15. Gastrointestinal Motility Disorders and Acupuncture

    PubMed Central

    Yin, Jieyun; Chen, Jiande D Z

    2010-01-01

    During the last decades, numerous studies have been performed to investigate the effects and mechanisms of acupuncture or electroacupuncture (EA) on gastrointestinal motility and patients with functional gastrointestinal diseases. A PubMed search was performed on this topic and all available studies published in English have been reviewed and evaluated. This review is organized based on the gastrointestinal organ (from the esophagus to the colon), components of gastrointestinal motility and the functional diseases related to specific motility disorders. It was found that the effects of acupuncture or EA on gastrointestinal motility were fairly consistent and the major acupuncture points used in these studies were ST36 and PC6. Gastric motility has been mostly studied, whereas much less information is available on the effect of EA on small and large intestinal motility or related disorders. A number of clinical studies have been published, investigating the therapeutic effects of EA on a number of functional gastrointestinal diseases, such as gastroesophageal reflux, functional dyspepsia and irritable bowel syndrome. However, the findings of these clinical studies were inconclusive. In summary, acupuncture or EA is able to alter gastrointestinal motility functions and improve gastrointestinal motility disorders. However, more studies are needed to establish the therapeutic roles of EA in treating functional gastrointestinal diseases. PMID:20363196

  16. Management of gastrointestinal haemorrhage

    PubMed Central

    Ghosh, S; Watts, D; Kinnear, M

    2002-01-01

    A variety of endoscopic haemostatic techniques have enabled major advances in the management of not only bleeding peptic ulcers and bleeding varices, but also in a variety of bleeding lesions in the small intestine and in the colon. Indeed, the development and widespread implementation of endoscopic haemostasis has been one of the most important developments in clinical gastroenterology in the past two decades. An increasingly ageing cohort of patients with multiple co-morbidity are being treated and therefore improving the outcome of gastrointestinal bleeding continues to pose major challenges. PMID:11796865

  17. Using Chief Complaints for Syndromic Surveillance: A Review of Chief Complaint Based Classifiers in North America

    PubMed Central

    Conway, Mike; Dowling, John N.; Chapman, Wendy W.

    2013-01-01

    A major goal of Natural Language Processing in the public health informatics domain is the automatic extraction and encoding of data stored in free text patient records. This extracted data can then be utilized by computerized systems to perform syndromic surveillance. In particular, the chief complaint — a short string that describes a patient’s symptoms — has come to be a vital resource for syndromic surveillance in the North American context due to its near ubiquity. This paper reviews fifteen systems in North America — at the city, county, state and federal level — that use chief complaints for syndromic surveillance. PMID:23602781

  18. Influence of complaints and singing style in singers voice handicap.

    PubMed

    Moreti, Felipe; Ávila, Maria Emília Barros de; Rocha, Clara; Borrego, Maria Cristina de Menezes; Oliveira, Gisele; Behlau, Mara

    2012-01-01

    The aim of this research was to verify whether the difference of singing styles and the presence of vocal complaints influence the perception of voice handicap of singers. One hundred eighteen singing voice handicap self-assessment protocols were selected: 17 popular singers with vocal complaints, 42 popular singers without complaints, 17 classic singers with complaints, and 42 classic singers without complaints. The groups were similar regarding age, gender and voice types. Both protocols used--Modern Singing Handicap Index (MSHI) and Classical Singing Handicap Index (CSHI)--have specific questions to their respective singing styles, and consist of 30 items equally divided into three subscales: disability (functional domain), handicap (emotional domain) and impairment (organic domain), answered according to the frequency of occurrence. Each subscale has a maximum of 40 points, and the total score is 120 points. The higher the score, the higher the singing voice handicap perceived. For statistical analysis, we used the ANOVA test, with 5% of significance. Classical and popular singers referred higher impairment, followed by disability and handicap. However, the degree of this perception varied according to the singing style and the presence of vocal complaints. The classical singers with vocal complaints showed higher voice handicap than popular singers with vocal complaints, while the classic singers without complaints reported lower handicap than popular singers without complaints. This evidences that classical singers have higher perception of their own voice, and that vocal disturbances in this group may cause greater voice handicap when compared to popular singers.

  19. Osteoporosis in Gastrointestinal Diseases.

    PubMed

    Krela-Kaźmierczak, Iwona; Szymczak, Aleksandra; Łykowska-Szuber, Liliana; Eder, Piotr; Linke, Krzysztof

    2016-01-01

    Secondary osteoporosis occurs as an isolated pathology or co-exists with types I and II osteoporosis. The gastroenterologist may come across osteoporosis or osteopenia in a patient with a gastrointestinal disease. This is often a young patient in whom investigations should be carried out and appropriate treatment initiated, aimed at preventing bone fractures and the formation of the best peak bone mass. Osteoporosis occurs in patients with the following conditions: Crohn's disease, ulcerative colitis, celiac disease, post gastrectomy patients, patients with short bowel syndrome, chronic hepatitis and cirrhosis, treated with steroids (steroid-induced osteoporosis) and patients using proton pump inhibitors chronically (state of achlorhydria). It is therefore necessary to approve a list of risk factors of secondary osteoporosis, the presence of which would be an indication for screening for osteoporosis, including a DXA study and the development of a separate algorithm for the therapeutic management of secondary osteoporosis accompanying gastrointestinal diseases, especially in premenopausal young women and young men, because there are currently no registered drugs with proven antifracture activity for this group of patients. PMID:26935513

  20. Gastrointestinal and nutritional issues in joint hypermobility syndrome/Ehlers-Danlos syndrome, hypermobility type.

    PubMed

    Castori, Marco; Morlino, Silvia; Pascolini, Giulia; Blundo, Carlo; Grammatico, Paola

    2015-03-01

    Gastrointestinal involvement is a well known complication of Ehlers-Danlos syndromes (EDSs), mainly in form of abdominal emergencies due to intestinal/abdominal vessels rupture in vascular EDS. In the last decade, a growing number of works investigated the relationship between a wide spectrum of chronic gastrointestinal complaints and various EDS forms, among which the hypermobility type (a.k.a. joint hypermobility syndrome; JHS/EDS-HT) was the most studied. The emerging findings depict a major role for gastrointestinal involvement in the health status and, consequently, management of JHS/EDS-HT patients. Nevertheless, fragmentation of knowledge limits its impact on practice within the boundaries of highly specialized clinics. In this paper, literature review on gastrointestinal manifestations in JHS/EDS-HT was carried out and identified papers categorized as (i) case-control/cohort studies associating (apparently non-syndromic) joint hypermobility and gastrointestinal involvement, (ii) case-control/cohort studies associating JHS/EDS-HT and gastrointestinal involvement, (iii) case reports/series on various gastrointestinal complications in (presumed) JHS/EDS-HT, and (iv) studies reporting gastrointestinal features in heterogeneous EDS patients' cohorts. Gastrointestinal manifestations of JHS/EDS-HT were organized and discussed in two categories, including structural anomalies (i.e., abdominal/diaphragmatic hernias, internal organ/pelvic prolapses, intestinal intussusceptions) and functional features (i.e., dysphagia, gastro-esophageal reflux, dyspepsia, recurrent abdominal pain, constipation/diarrhea), with emphasis on practice and future implications. In the second part of this paper, a summary of possible nutritional interventions in JHS/EDS-HT was presented. Supplementation strategies were borrowed from data available for general population with minor modifications in the light of recent discoveries in the pathogenesis of selected JHS/EDS-HT features.

  1. Gastrointestinal and nutritional issues in joint hypermobility syndrome/Ehlers-Danlos syndrome, hypermobility type.

    PubMed

    Castori, Marco; Morlino, Silvia; Pascolini, Giulia; Blundo, Carlo; Grammatico, Paola

    2015-03-01

    Gastrointestinal involvement is a well known complication of Ehlers-Danlos syndromes (EDSs), mainly in form of abdominal emergencies due to intestinal/abdominal vessels rupture in vascular EDS. In the last decade, a growing number of works investigated the relationship between a wide spectrum of chronic gastrointestinal complaints and various EDS forms, among which the hypermobility type (a.k.a. joint hypermobility syndrome; JHS/EDS-HT) was the most studied. The emerging findings depict a major role for gastrointestinal involvement in the health status and, consequently, management of JHS/EDS-HT patients. Nevertheless, fragmentation of knowledge limits its impact on practice within the boundaries of highly specialized clinics. In this paper, literature review on gastrointestinal manifestations in JHS/EDS-HT was carried out and identified papers categorized as (i) case-control/cohort studies associating (apparently non-syndromic) joint hypermobility and gastrointestinal involvement, (ii) case-control/cohort studies associating JHS/EDS-HT and gastrointestinal involvement, (iii) case reports/series on various gastrointestinal complications in (presumed) JHS/EDS-HT, and (iv) studies reporting gastrointestinal features in heterogeneous EDS patients' cohorts. Gastrointestinal manifestations of JHS/EDS-HT were organized and discussed in two categories, including structural anomalies (i.e., abdominal/diaphragmatic hernias, internal organ/pelvic prolapses, intestinal intussusceptions) and functional features (i.e., dysphagia, gastro-esophageal reflux, dyspepsia, recurrent abdominal pain, constipation/diarrhea), with emphasis on practice and future implications. In the second part of this paper, a summary of possible nutritional interventions in JHS/EDS-HT was presented. Supplementation strategies were borrowed from data available for general population with minor modifications in the light of recent discoveries in the pathogenesis of selected JHS/EDS-HT features. PMID

  2. Gastrointestinal Headache; a Narrative Review

    PubMed Central

    T Noghani, Majid; Rezaeizadeh, Hossein; Fazljoo, Sayed Mohammad Baqer; Keshavarz, Mansoor

    2016-01-01

    There are studies reporting primary headaches to be associated with gastrointestinal disorders, and some report resolution of headache following the treatment of the associated gastrointestinal disorder. Headache disorders are classified by The International Headache Society as primary or secondary; however, among the secondary headaches, those attributed to gastrointestinal disorders are not appreciated. Therefore, we aimed to review the literature to provide evidence for headaches, which originate from the gastrointestinal system. Gastrointestinal disorders that are reported to be associated with primary headaches include dyspepsia, gastro esophageal reflux disease (GERD), constipation, functional abdominal pain, inflammatory bowel syndrome (IBS), inflammatory bowel disorders (IBD), celiac disease, and helicobacter pylori (H. Pylori) infection. Some studies have demonstrated remission or improvement of headache following the treatment of the accompanying gastrointestinal disorders. Hypotheses explaining this association are considered to be central sensitization and parasympathetic referred pain, serotonin pathways, autonomic nervous system dysfunction, systemic vasculopathy, and food allergy. Traditional Persian physicians, namely Ebn-e-Sina (Avicenna) and Râzi (Rhazes) believed in a type of headache originating from disorders of the stomach and named it as an individual entity, the "Participatory Headache of Gastric Origin". We suggest providing a unique diagnostic entity for headaches coexisting with any gastrointestinal abnormality that are improved or cured along with the treatment of the gastrointestinal disorder. PMID:27800536

  3. Meteorite Atmospheric Entry Reproduced in Plasmatron

    NASA Astrophysics Data System (ADS)

    Pittarello, L.; McKibbin, S.; Goderis, S.; Soens, B.; Bariselli, F.; Barros Dias, B. R.; Zavalan, F. L.; Magin, T.; Claeys, Ph.

    2016-08-01

    Plasmatron facility allows experimental conditions that reproduce atmospheric entry of meteorites. Tests on basalt, as meteorite analogue, have been performed. Preliminary results have highlighted melting and evaporation effects.

  4. Intellectual Freedom and the Handling of Complaints. Phase II: Initiation and Handling of the Complaint

    ERIC Educational Resources Information Center

    Jones, Harry; Lawson, Ray

    1973-01-01

    The parent of a student complained that Slaughterhouse Five'' was profane, obscene, and anti-religious and should be banned from school use. The past president agreed and informally requested that the book be removed, thus initiating events leading to a formal complaint. (Author/SJ)

  5. [Obesity and gastrointestinal motility].

    PubMed

    Lee, Joon Seong

    2006-08-01

    Gastrointestinal (GI) motility has a crucial role in the food consumption, digestion and absorption, and also controls the appetite and satiety. In obese patients, various alterations of GI motility have been investigated. The prevalence of GERD and esophageal motor disorders in obese patients are higher than those of general population. Gastric emptying of solid food is generally accelerated and fasting gastric volume especially in distal stomach is larger in obese patients without change in accommodation. Contractile activity of small intestine in fasting period is more prominent, but orocecal transit is delayed. Autonomic dysfunction is frequently demonstrated in obese patients. These findings correspond with increased appetite and delayed satiety in obese patients, but causes or results have not been confirmed. Therapeutic interventions of these altered GI motility have been developed using botulinum toxin, gastric electrical stimulation in obese patients. Novel agents targeted for GI hormone modulation (such as ghrelin and leptin) need to be developed in the near future. PMID:16929152

  6. Disorders of gastrointestinal hypomotility

    PubMed Central

    Bielefeldt, Klaus; Tuteja, Ashok; Nusrat, Salman

    2016-01-01

    Ingestion and digestion of food as well as expulsion of residual material from our gastrointestinal tract requires normal propulsive, i.e. motor, function. Hypomotility refers to inherited or acquired changes that come with decreased contractile forces or slower transit. It not only often causes symptoms but also may compromise nutritional status or lead to other complications. While severe forms, such as pseudo-obstruction or ileus, may have a tremendous functional impact, the less severe forms of hypomotility may well be more relevant, as they contribute to common disorders, such as functional dyspepsia, gastroparesis, chronic constipation, and irritable bowel syndrome (IBS). Clinical testing can identify changes in contractile activity, defined by lower amplitudes or abnormal patterns, and the related effects on transit. However, such biomarkers show a limited correlation with overall symptom severity as experienced by patients. Similarly, targeting hypomotility with pharmacological interventions often alters gut motor function but does not consistently improve symptoms. Novel diagnostic approaches may change this apparent paradox and enable us to obtain more comprehensive information by integrating data on electrical activity, mechanical forces, patterns, wall stiffness, and motions with information of the flow of luminal contents. New drugs with more selective effects or more specific delivery may improve benefits and limit adverse effects. Lastly, the complex regulation of gastrointestinal motility involves the brain-gut axis as a reciprocal pathway for afferent and efferent signaling. Considering the role of visceral input in emotion and the effects of emotion on visceral activity, understanding and managing hypomotility disorders requires an integrative approach based on the mind-body continuum or biopsychosocial model of diseases. PMID:27583135

  7. Disorders of gastrointestinal hypomotility.

    PubMed

    Bielefeldt, Klaus; Tuteja, Ashok; Nusrat, Salman

    2016-01-01

    Ingestion and digestion of food as well as expulsion of residual material from our gastrointestinal tract requires normal propulsive, i.e. motor, function. Hypomotility refers to inherited or acquired changes that come with decreased contractile forces or slower transit. It not only often causes symptoms but also may compromise nutritional status or lead to other complications. While severe forms, such as pseudo-obstruction or ileus, may have a tremendous functional impact, the less severe forms of hypomotility may well be more relevant, as they contribute to common disorders, such as functional dyspepsia, gastroparesis, chronic constipation, and irritable bowel syndrome (IBS). Clinical testing can identify changes in contractile activity, defined by lower amplitudes or abnormal patterns, and the related effects on transit. However, such biomarkers show a limited correlation with overall symptom severity as experienced by patients. Similarly, targeting hypomotility with pharmacological interventions often alters gut motor function but does not consistently improve symptoms. Novel diagnostic approaches may change this apparent paradox and enable us to obtain more comprehensive information by integrating data on electrical activity, mechanical forces, patterns, wall stiffness, and motions with information of the flow of luminal contents. New drugs with more selective effects or more specific delivery may improve benefits and limit adverse effects. Lastly, the complex regulation of gastrointestinal motility involves the brain-gut axis as a reciprocal pathway for afferent and efferent signaling. Considering the role of visceral input in emotion and the effects of emotion on visceral activity, understanding and managing hypomotility disorders requires an integrative approach based on the mind-body continuum or biopsychosocial model of diseases. PMID:27583135

  8. Auditory complaints in scuba divers: an overview.

    PubMed

    Evens, Rachel A; Bardsley, Barry; C Manchaiah, Vinaya K

    2012-03-01

    Pre-1970s, diving was seen as a predominantly male working occupation. Since then it has become a popular hobby, with increasing access to SCUBA diving while on holiday. For a leisure activity, diving puts the auditory system at the risk of a wide variety of complaints. However, there is still insufficient consensus on the frequency of these conditions, which ultimately would require more attention from hearing-healthcare professionals. A literature search of epidemiology studies of eight auditory complaints was conducted, using both individual and large-scale diving studies, with some reference to large-scale non-diving populations . A higher incidence was found for middle ear barotrauma, eustachian tube dysfunction, and alternobaric vertigo with a high correlation among females. Comparing these findings with a non-diving population found no statistically significant difference for hearing loss or tinnitus. Increased awareness of health professionals is required, training, and implementation of the Frenzel technique would help resolve the ambiguities of the Valsalva technique underwater. PMID:23448900

  9. Auditory complaints in scuba divers: an overview.

    PubMed

    Evens, Rachel A; Bardsley, Barry; C Manchaiah, Vinaya K

    2012-03-01

    Pre-1970s, diving was seen as a predominantly male working occupation. Since then it has become a popular hobby, with increasing access to SCUBA diving while on holiday. For a leisure activity, diving puts the auditory system at the risk of a wide variety of complaints. However, there is still insufficient consensus on the frequency of these conditions, which ultimately would require more attention from hearing-healthcare professionals. A literature search of epidemiology studies of eight auditory complaints was conducted, using both individual and large-scale diving studies, with some reference to large-scale non-diving populations . A higher incidence was found for middle ear barotrauma, eustachian tube dysfunction, and alternobaric vertigo with a high correlation among females. Comparing these findings with a non-diving population found no statistically significant difference for hearing loss or tinnitus. Increased awareness of health professionals is required, training, and implementation of the Frenzel technique would help resolve the ambiguities of the Valsalva technique underwater.

  10. Explorations in statistics: statistical facets of reproducibility.

    PubMed

    Curran-Everett, Douglas

    2016-06-01

    Learning about statistics is a lot like learning about science: the learning is more meaningful if you can actively explore. This eleventh installment of Explorations in Statistics explores statistical facets of reproducibility. If we obtain an experimental result that is scientifically meaningful and statistically unusual, we would like to know that our result reflects a general biological phenomenon that another researcher could reproduce if (s)he repeated our experiment. But more often than not, we may learn this researcher cannot replicate our result. The National Institutes of Health and the Federation of American Societies for Experimental Biology have created training modules and outlined strategies to help improve the reproducibility of research. These particular approaches are necessary, but they are not sufficient. The principles of hypothesis testing and estimation are inherent to the notion of reproducibility in science. If we want to improve the reproducibility of our research, then we need to rethink how we apply fundamental concepts of statistics to our science.

  11. 31 CFR 15.737-13 - Service of complaint and other papers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Service of complaint and other papers... other papers. (a) Complaint. The complaint or a copy thereof may be served upon the respondent by... of papers other than complaint. Any paper other than the complaint may be served upon a respondent...

  12. Functional Gastrointestinal Disorders in a Primary Care Pediatric Clinic

    PubMed Central

    Chelimsky, Thomas; Li, Hong; Chelimsky, Gisela

    2015-01-01

    Functional gastrointestinal disorders (FGIDs) are a common problem in pediatric patients and can affect quality of life. However, the extent of these disorders may vary in different subpopulations of children. This study investigated the prevalence of FGIDs in an inner-city primary care practice. Healthy patients between the ages of 9 and 17 were administered a validated questionnaire that assessed for FGIDs and other somatic complaints. Eleven of 145 patients (7.5%) met criteria for FGIDs based on Rome III Diagnostic Criteria. Raynaud-like symptoms tended to occur more often in patients meeting criteria for FGIDs, although this association was not statistically significant (P = .07). The lower prevalence of FGIDs in this population compared with earlier studies may suggest a link between socioeconomic status and the prevalence of FGIDs. Larger population-based studies consisting of a heterogeneous cohort from a variety of socioeconomic backgrounds are necessary to further elucidate the true connection between FGIDs and socioeconomic status. PMID:27335938

  13. Probiotic Claims for Gastrointestinal Conditions: Stretching the Truth?

    PubMed

    Miller, Larry E

    2014-08-21

    ABSTRACT Probiotics are live micro-organisms that confer a health benefit on the host when administered in adequate dosages and have been extensively studied for treatment of gastrointestinal (GI) disorders. While a growing body of evidence from randomized controlled trials supports the use of probiotics for a variety of GI conditions, the media and internet are saturated with advertisements falsely claiming that specific probiotic strains or strain combinations can improve, or even cure, many GI complaints. These unsubstantiated claims regarding probiotic efficacy are rampant and remain largely unregulated. The probiotic industry is strongly encouraged to close the gap between marketing hype and scientific discovery. Additionally, US regulators are encouraged to improve enforcement efforts in response to misleading probiotic advertising. PMID:25144765

  14. 40 CFR 135.4 - Service of complaint.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Service of complaint. 135.4 Section 135.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.4 Service of complaint. (a)...

  15. 40 CFR 135.4 - Service of complaint.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Service of complaint. 135.4 Section 135.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.4 Service of complaint. (a)...

  16. 5 CFR 1201.123 - Contents of complaint.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Contents of complaint. 1201.123 Section 1201.123 Administrative Personnel MERIT SYSTEMS PROTECTION BOARD ORGANIZATION AND PROCEDURES PRACTICES....123 Contents of complaint. (a) If the Special Counsel determines that the Board should take any of...

  17. 7 CFR 46.49 - Written notifications and complaints.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 2 2013-01-01 2013-01-01 false Written notifications and complaints. 46.49 Section 46... No. § 46.49 Written notifications and complaints. (a) Written notification, as used in section 6(b) of the Act, means: (1) Any written statement reporting or complaining of a PACA violation(s) filed...

  18. 7 CFR 46.49 - Written notifications and complaints.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false Written notifications and complaints. 46.49 Section 46... No. § 46.49 Written notifications and complaints. (a) Written notification, as used in section 6(b) of the Act, means: (1) Any written statement reporting or complaining of a PACA violation(s) filed...

  19. 7 CFR 46.49 - Written notifications and complaints.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 2 2011-01-01 2011-01-01 false Written notifications and complaints. 46.49 Section 46... No. § 46.49 Written notifications and complaints. (a) Written notification, as used in section 6(b) of the Act, means: (1) Any written statement reporting or complaining of a PACA violation(s) filed...

  20. 7 CFR 6.42 - Complaints of price-undercutting.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Cheese by Quota Cheeses § 6.42 Complaints of price-undercutting. (a) Submission of complaint. Any person who has reason to believe that the price at which any article of quota cheese is offered for sale or... a subsidy with respect to such article of quota cheese may file with the Investigating Authority...

  1. 7 CFR 6.42 - Complaints of price-undercutting.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Cheese by Quota Cheeses § 6.42 Complaints of price-undercutting. (a) Submission of complaint. Any person who has reason to believe that the price at which any article of quota cheese is offered for sale or... a subsidy with respect to such article of quota cheese may file with the Investigating Authority...

  2. 7 CFR 6.42 - Complaints of price-undercutting.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Cheese by Quota Cheeses § 6.42 Complaints of price-undercutting. (a) Submission of complaint. Any person who has reason to believe that the price at which any article of quota cheese is offered for sale or... a subsidy with respect to such article of quota cheese may file with the Investigating Authority...

  3. 7 CFR 6.42 - Complaints of price-undercutting.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Cheese by Quota Cheeses § 6.42 Complaints of price-undercutting. (a) Submission of complaint. Any person who has reason to believe that the price at which any article of quota cheese is offered for sale or... a subsidy with respect to such article of quota cheese may file with the Investigating Authority...

  4. 29 CFR 1614.105 - Pre-complaint processing.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... sufficient by the agency or the Commission. (b)(1) At the initial counseling session, Counselors must advise... claims raised in precomplaint counseling (or issues or claims like or related to issues or claims raised in pre-complaint counseling) may be alleged in a subsequent complaint filed with the...

  5. 47 CFR 68.417 - Informal complaints; form and content.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Informal complaints; form and content. 68.417 Section 68.417 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) CONNECTION OF TERMINAL EQUIPMENT TO THE TELEPHONE NETWORK Complaint Procedures § 68.417...

  6. 32 CFR 1907.04 - Suggestions and complaints.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....04 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY... General § 1907.04 Suggestions and complaints. The Agency welcomes suggestions or complaints with regard to... specific purpose and the issues for consideration. The Agency will respond to all...

  7. 32 CFR 1907.04 - Suggestions and complaints.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....04 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY... General § 1907.04 Suggestions and complaints. The Agency welcomes suggestions or complaints with regard to... specific purpose and the issues for consideration. The Agency will respond to all...

  8. 32 CFR 1907.04 - Suggestions and complaints.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....04 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY... General § 1907.04 Suggestions and complaints. The Agency welcomes suggestions or complaints with regard to... specific purpose and the issues for consideration. The Agency will respond to all...

  9. 22 CFR 96.70 - Operation of the Complaint Registry.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Operation of the Complaint Registry. 96.70 Section 96.70 Foreign Relations DEPARTMENT OF STATE LEGAL AND RELATED SERVICES ACCREDITATION OF AGENCIES AND APPROVAL OF PERSONS UNDER THE INTERCOUNTRY ADOPTION ACT OF 2000 (IAA) Oversight Through Review of Complaints § 96.70 Operation of the...

  10. 18 CFR 385.206 - Complaints (Rule 206).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... electronic media as specified by the Secretary. (11) Explain with respect to requests for Fast Track... be due. (g) Complaint resolution paths. One of the following procedures may be used to resolve... before an ALJ; (h) Fast Track processing. (1) The Commission may resolve complaints using Fast...

  11. 18 CFR 385.206 - Complaints (Rule 206).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... electronic media as specified by the Secretary. (11) Explain with respect to requests for Fast Track... be due. (g) Complaint resolution paths. One of the following procedures may be used to resolve... before an ALJ; (h) Fast Track processing. (1) The Commission may resolve complaints using Fast...

  12. 18 CFR 385.206 - Complaints (Rule 206).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... electronic media as specified by the Secretary. (11) Explain with respect to requests for Fast Track... be due. (g) Complaint resolution paths. One of the following procedures may be used to resolve... before an ALJ; (h) Fast Track processing. (1) The Commission may resolve complaints using Fast...

  13. 40 CFR 135.4 - Service of complaint.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Service of complaint. 135.4 Section 135.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.4 Service of complaint. (a) A...

  14. 47 CFR 3.52 - Complaint/inquiry resolution procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Complaint/inquiry resolution procedures. 3.52 Section 3.52 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL AUTHORIZATION AND ADMINISTRATION... Operations § 3.52 Complaint/inquiry resolution procedures. (a) Accounting authorities must...

  15. 40 CFR 27.6 - Prerequisites for issuing a complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Prerequisites for issuing a complaint. 27.6 Section 27.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROGRAM FRAUD CIVIL REMEDIES § 27.6 Prerequisites for issuing a complaint. (a) The reviewing official may issue...

  16. 29 CFR 1982.103 - Filing of retaliation complaints.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... IMPLEMENTING RECOMMENDATIONS OF THE 9/11 COMMISSION ACT OF 2007 Complaints, Investigations, Findings and... 29 Labor 9 2014-07-01 2014-07-01 false Filing of retaliation complaints. 1982.103 Section 1982.103... TRANSIT SYSTEMS SECURITY ACT OF 2007, ENACTED AS SECTION 1413 OF THE IMPLEMENTING RECOMMENDATIONS OF THE...

  17. 29 CFR 1982.103 - Filing of retaliation complaints.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... IMPLEMENTING RECOMMENDATIONS OF THE 9/11 COMMISSION ACT OF 2007 Complaints, Investigations, Findings and... 29 Labor 9 2011-07-01 2011-07-01 false Filing of retaliation complaints. 1982.103 Section 1982.103... TRANSIT SYSTEMS SECURITY ACT OF 2007, ENACTED AS SECTION 1413 OF THE IMPLEMENTING RECOMMENDATIONS OF THE...

  18. 29 CFR 1982.103 - Filing of retaliation complaints.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... IMPLEMENTING RECOMMENDATIONS OF THE 9/11 COMMISSION ACT OF 2007 Complaints, Investigations, Findings and... 29 Labor 9 2012-07-01 2012-07-01 false Filing of retaliation complaints. 1982.103 Section 1982.103... TRANSIT SYSTEMS SECURITY ACT OF 2007, ENACTED AS SECTION 1413 OF THE IMPLEMENTING RECOMMENDATIONS OF THE...

  19. 29 CFR 1982.103 - Filing of retaliation complaints.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... IMPLEMENTING RECOMMENDATIONS OF THE 9/11 COMMISSION ACT OF 2007 Complaints, Investigations, Findings and... 29 Labor 9 2013-07-01 2013-07-01 false Filing of retaliation complaints. 1982.103 Section 1982.103... TRANSIT SYSTEMS SECURITY ACT OF 2007, ENACTED AS SECTION 1413 OF THE IMPLEMENTING RECOMMENDATIONS OF THE...

  20. 34 CFR 303.432 - Adoption of State complaint procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false Adoption of State complaint procedures. 303.432 Section 303.432 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... INFANTS AND TODDLERS WITH DISABILITIES Procedural Safeguards State Complaint Procedures § 303.432...

  1. 34 CFR 300.151 - Adoption of State complaint procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Adoption of State complaint procedures. 300.151 Section 300.151 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... EDUCATION OF CHILDREN WITH DISABILITIES State Eligibility State Complaint Procedures § 300.151 Adoption...

  2. 34 CFR 303.432 - Adoption of State complaint procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true Adoption of State complaint procedures. 303.432 Section 303.432 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... INFANTS AND TODDLERS WITH DISABILITIES Procedural Safeguards State Complaint Procedures § 303.432...

  3. 34 CFR 300.151 - Adoption of State complaint procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true Adoption of State complaint procedures. 300.151 Section 300.151 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... EDUCATION OF CHILDREN WITH DISABILITIES State Eligibility State Complaint Procedures § 300.151 Adoption...

  4. 34 CFR 303.432 - Adoption of State complaint procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false Adoption of State complaint procedures. 303.432 Section 303.432 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... INFANTS AND TODDLERS WITH DISABILITIES Procedural Safeguards State Complaint Procedures § 303.432...

  5. 34 CFR 300.151 - Adoption of State complaint procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false Adoption of State complaint procedures. 300.151 Section 300.151 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... EDUCATION OF CHILDREN WITH DISABILITIES State Eligibility State Complaint Procedures § 300.151 Adoption...

  6. 34 CFR 300.151 - Adoption of State complaint procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true Adoption of State complaint procedures. 300.151 Section 300.151 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... EDUCATION OF CHILDREN WITH DISABILITIES State Eligibility State Complaint Procedures § 300.151 Adoption...

  7. 34 CFR 300.151 - Adoption of State complaint procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false Adoption of State complaint procedures. 300.151 Section 300.151 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... EDUCATION OF CHILDREN WITH DISABILITIES State Eligibility State Complaint Procedures § 300.151 Adoption...

  8. 29 CFR 1980.103 - Filing of retaliation complaints.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false Filing of retaliation complaints. 1980.103 Section 1980.103 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER SECTION 806 OF THE SARBANES-OXLEY ACT OF 2002, AS...

  9. 29 CFR 24.103 - Filing of retaliation complaint.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Filing of retaliation complaint. 24.103 Section 24.103 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF THE ENERGY...

  10. 29 CFR 24.103 - Filing of retaliation complaint.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Filing of retaliation complaint. 24.103 Section 24.103 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF THE ENERGY...

  11. 29 CFR 24.103 - Filing of retaliation complaint.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Filing of retaliation complaint. 24.103 Section 24.103 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF THE ENERGY...

  12. 29 CFR 24.103 - Filing of retaliation complaint.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Filing of retaliation complaint. 24.103 Section 24.103 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF THE ENERGY REORGANIZATION ACT OF...

  13. 32 CFR 806b.4 - Privacy Act complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Privacy Act complaints. 806b.4 Section 806b.4 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ADMINISTRATION PRIVACY ACT PROGRAM Overview of the Privacy Act Program § 806b.4 Privacy Act complaints. (a) Process Privacy...

  14. 20 CFR 638.539 - Complaints and disputes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... programs receiving financial assistance under JTPA. (2) 29 CFR part 33 for programs conducted by the... 60 days after the filing of the complaint. Except for a complaint alleging fraud or criminal activity... Contract Disputes Act and 41 CFR part 29-60. (f) Inter-agency disputes. A dispute between DOL and a...

  15. 22 CFR 96.70 - Operation of the Complaint Registry.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Operation of the Complaint Registry. 96.70 Section 96.70 Foreign Relations DEPARTMENT OF STATE LEGAL AND RELATED SERVICES ACCREDITATION OF AGENCIES AND APPROVAL OF PERSONS UNDER THE INTERCOUNTRY ADOPTION ACT OF 2000 (IAA) Oversight Through Review of Complaints § 96.70 Operation of the...

  16. 7 CFR 46.49 - Written notifications and complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Written notifications and complaints. 46.49 Section 46... No. § 46.49 Written notifications and complaints. (a) Written notification, as used in section 6(b) of the Act, means: (1) Any written statement reporting or complaining of a PACA violation(s) filed...

  17. 48 CFR 203.905 - Procedures for investigating complaints.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... investigating complaints. 203.905 Section 203.905 Federal Acquisition Regulations System DEFENSE ACQUISITION... INTEREST Whistleblower Protections for Contractor Employees 203.905 Procedures for investigating complaints... allege a violation of the prohibition in 203.903, or has been previously addressed in another Federal...

  18. 49 CFR 1313.10 - Procedures for complaints and discovery.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Procedures for complaints and discovery. 1313.10... TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) CARRIER RATES AND SERVICE TERMS RAILROAD CONTRACTS FOR THE TRANSPORTATION OF AGRICULTURAL PRODUCTS § 1313.10 Procedures for complaints and discovery....

  19. 49 CFR 1313.10 - Procedures for complaints and discovery.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Procedures for complaints and discovery. 1313.10... TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) CARRIER RATES AND SERVICE TERMS RAILROAD CONTRACTS FOR THE TRANSPORTATION OF AGRICULTURAL PRODUCTS § 1313.10 Procedures for complaints and discovery....

  20. 49 CFR 1313.10 - Procedures for complaints and discovery.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Procedures for complaints and discovery. 1313.10... TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) CARRIER RATES AND SERVICE TERMS RAILROAD CONTRACTS FOR THE TRANSPORTATION OF AGRICULTURAL PRODUCTS § 1313.10 Procedures for complaints and discovery....

  1. 49 CFR 1313.10 - Procedures for complaints and discovery.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Procedures for complaints and discovery. 1313.10... TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) CARRIER RATES AND SERVICE TERMS RAILROAD CONTRACTS FOR THE TRANSPORTATION OF AGRICULTURAL PRODUCTS § 1313.10 Procedures for complaints and discovery....

  2. 49 CFR 1313.10 - Procedures for complaints and discovery.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Procedures for complaints and discovery. 1313.10... TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) CARRIER RATES AND SERVICE TERMS RAILROAD CONTRACTS FOR THE TRANSPORTATION OF AGRICULTURAL PRODUCTS § 1313.10 Procedures for complaints and discovery....

  3. 29 CFR 102.96 - Issuance of complaint promptly.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Issuance of complaint promptly. 102.96 Section 102.96 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD RULES AND REGULATIONS, SERIES 8 Procedure in Cases Under Section 10(j), (l), and (m) of the Act § 102.96 Issuance of complaint promptly. Whenever...

  4. Statistical analysis of unsolicited thermal sensation complaints in commercial buildings

    SciTech Connect

    Federspiel, C.C.

    1998-10-01

    Unsolicited complaints from 23,500 occupants in 690 commercial buildings were examined with regard to absolute and relative frequency of complaints, temperatures at which thermal sensation complaints (too hot or too cold) occurred, and response times and actions. The analysis shows that thermal sensation complaints are the single most common complaint of any type and that they are the overwhelming majority of environmental complaints. The analysis indicates that thermal sensation complaints are mostly the result of poor control performance and HVAC system faults rather than inter-individual differences in preferred temperatures. The analysis also shows that the neutral temperature in summer is greater than in winter, and the difference between summer and winter neutral temperatures is smaller than the difference between the midpoints of the summer and winter ASHRAE comfort zones. On average, women complain that it is cold at a higher temperature than men, and the temperature at which men complain that it is hot is more variable than for women. Analysis of response times and actions provides information that may be useful for designing a dispatching policy, and it also demonstrates that there is potential to reduce the labor cost of HVAC maintenance by 20% by reducing the frequency of thermal sensation complaints.

  5. 29 CFR 1987.103 - Filing of retaliation complaint.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false Filing of retaliation complaint. 1987.103 Section 1987.103 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR HANDLING RETALIATION COMPLAINTS UNDER SECTION 402 OF THE...

  6. 29 CFR 1979.103 - Filing of discrimination complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Filing of discrimination complaint. 1979.103 Section 1979.103 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF DISCRIMINATION COMPLAINTS UNDER SECTION 519...

  7. 29 CFR 1981.103 - Filing of discrimination complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Filing of discrimination complaint. 1981.103 Section 1981.103 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF DISCRIMINATION COMPLAINTS UNDER SECTION 6...

  8. 12 CFR 268.302 - Mixed case complaints.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... jurisdiction. The Board will apply sections 1614.302 to 1614.310 of 29 CFR to the processing of a mixed case... complaint is a complaint of employment discrimination filed with the Board based on race, color, religion... whole or in part, because of discrimination on the basis of race, color, religion, sex, national...

  9. 40 CFR 7.180 - Mediation of age discrimination complaints.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Mediation of age discrimination... Discrimination Prohibited on the Basis of Age § 7.180 Mediation of age discrimination complaints. (a) The OCR will refer all accepted complaints alleging age discrimination to the Mediation Agency designated...

  10. 40 CFR 7.180 - Mediation of age discrimination complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Mediation of age discrimination... Discrimination Prohibited on the Basis of Age § 7.180 Mediation of age discrimination complaints. (a) The OCR will refer all accepted complaints alleging age discrimination to the Mediation Agency designated...

  11. 40 CFR 7.180 - Mediation of age discrimination complaints.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Mediation of age discrimination... Discrimination Prohibited on the Basis of Age § 7.180 Mediation of age discrimination complaints. (a) The OCR will refer all accepted complaints alleging age discrimination to the Mediation Agency designated...

  12. 40 CFR 7.180 - Mediation of age discrimination complaints.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Mediation of age discrimination... Discrimination Prohibited on the Basis of Age § 7.180 Mediation of age discrimination complaints. (a) The OCR will refer all accepted complaints alleging age discrimination to the Mediation Agency designated...

  13. 40 CFR 7.180 - Mediation of age discrimination complaints.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Mediation of age discrimination... Discrimination Prohibited on the Basis of Age § 7.180 Mediation of age discrimination complaints. (a) The OCR will refer all accepted complaints alleging age discrimination to the Mediation Agency designated...

  14. 49 CFR 1111.6 - Satisfaction of complaint.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 8 2011-10-01 2011-10-01 false Satisfaction of complaint. 1111.6 Section 1111.6 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE COMPLAINT AND INVESTIGATION PROCEDURES § 1111.6 Satisfaction...

  15. 49 CFR 1111.6 - Satisfaction of complaint.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Satisfaction of complaint. 1111.6 Section 1111.6 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE COMPLAINT AND INVESTIGATION PROCEDURES § 1111.6 Satisfaction...

  16. 29 CFR 1603.102 - Filing a complaint.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... appear in 29 CFR 1610.4. (c) Contents of a complaint. A complaint shall be in writing, signed and... alleged unlawful employment practices (See 29 CFR 1601.15(b)); and (4) A statement disclosing whether... filed pursuant to 29 CFR part 1601 or part 1626, that is later deemed to be a matter under this...

  17. 29 CFR 102.96 - Issuance of complaint promptly.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 2 2011-07-01 2011-07-01 false Issuance of complaint promptly. 102.96 Section 102.96 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD RULES AND REGULATIONS, SERIES 8 Procedure in Cases Under Section 10(j), (l), and (m) of the Act § 102.96 Issuance of complaint promptly. Whenever...

  18. 47 CFR 68.419 - Answers to informal complaints.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Answers to informal complaints. 68.419 Section 68.419 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) CONNECTION OF TERMINAL EQUIPMENT TO THE TELEPHONE NETWORK Complaint Procedures § 68.419...

  19. 47 CFR 76.1606 - Rate change while complaint pending.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Rate change while complaint pending. 76.1606 Section 76.1606 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Notices § 76.1606 Rate change while complaint pending....

  20. 37 CFR 4.1 - Complaints regarding invention promoters.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... invention promoters. 4.1 Section 4.1 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL COMPLAINTS REGARDING INVENTION PROMOTERS § 4.1 Complaints regarding invention promoters. These regulations govern the Patent and Trademark Office's...

  1. 37 CFR 4.1 - Complaints regarding invention promoters.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... invention promoters. 4.1 Section 4.1 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL COMPLAINTS REGARDING INVENTION PROMOTERS § 4.1 Complaints regarding invention promoters. These regulations govern the Patent and Trademark Office's...

  2. 29 CFR 1603.103 - Referral of complaints.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE GOVERNMENT EMPLOYEE RIGHTS ACT OF 1991 Administrative Process § 1603.103 Referral of complaints... filed by a state or local government employee or applicant under this part concerning an...

  3. 29 CFR 1981.103 - Filing of discrimination complaint.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false Filing of discrimination complaint. 1981.103 Section 1981.103 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF DISCRIMINATION COMPLAINTS UNDER SECTION 6...

  4. 29 CFR 1979.103 - Filing of discrimination complaint.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false Filing of discrimination complaint. 1979.103 Section 1979.103 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF DISCRIMINATION COMPLAINTS UNDER SECTION 519...

  5. 29 CFR 1980.103 - Filing of discrimination complaint.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false Filing of discrimination complaint. 1980.103 Section 1980.103 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF DISCRIMINATION COMPLAINTS UNDER SECTION 806...

  6. 12 CFR 268.302 - Mixed case complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... jurisdiction. The Board will apply sections 1614.302 to 1614.310 of 29 CFR to the processing of a mixed case... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Mixed case complaints. 268.302 Section 268.302... RULES REGARDING EQUAL OPPORTUNITY Related Processes § 268.302 Mixed case complaints. A mixed...

  7. 12 CFR 308.507 - Service of complaint.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Service of complaint. 308.507 Section 308.507 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.507 Service of complaint....

  8. 12 CFR 308.507 - Service of complaint.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Service of complaint. 308.507 Section 308.507 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.507 Service of complaint....

  9. 12 CFR 308.507 - Service of complaint.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Service of complaint. 308.507 Section 308.507 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.507 Service of complaint....

  10. 12 CFR 308.507 - Service of complaint.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Service of complaint. 308.507 Section 308.507 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.507 Service of complaint....

  11. 12 CFR 308.507 - Service of complaint.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 5 2012-01-01 2012-01-01 false Service of complaint. 308.507 Section 308.507 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Program Fraud Civil Remedies and Procedures § 308.507 Service of complaint....

  12. 29 CFR 101.9 - Settlement after issuance of complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... nature of the proceeding, and the public interest do not permit. (b)(1) After the issuance of a complaint... 29 Labor 2 2010-07-01 2010-07-01 false Settlement after issuance of complaint. 101.9 Section 101.9 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD STATEMENTS OF PROCEDURES Unfair...

  13. 41 CFR 60-30.32 - Administrative complaint and answer.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Administrative complaint and answer. 60-30.32 Section 60-30.32 Public Contracts and Property Management Other Provisions...) Expedited hearings shall be commenced by filing an administrative complaint in accordance with 41 CFR...

  14. 47 CFR 1.721 - Format and content of complaints.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., Applications, Tariffs, and Reports Involving Common Carriers Formal Complaints § 1.721 Format and content of... identify such persons, documents, data compilations, tangible things, and information; (11) Copies of all... 47 Telecommunication 1 2011-10-01 2011-10-01 false Format and content of complaints. 1.721...

  15. Cognitive complaint in mild cognitive impairment and Alzheimer's disease.

    PubMed

    Clément, Francis; Belleville, Sylvie; Gauthier, Serge

    2008-03-01

    Whereas the presence of a subjective memory complaint is a central criteria for mild cognitive impairment (MCI), little work has been done to empirically measure its nature and severity. The Self-Evaluation Questionnaire (QAM) assessed memory complaints relative to 10 domains of concrete activities of daily life in 68 persons with MCI, 26 persons with Alzheimer's disease (AD), and 81 healthy older adults. In addition, a neuropsychological battery was administered to assess whether subjective complaints were linked to actual cognitive performance. The findings indicate that individuals with MCI report more memory complaints than controls for a range of specific materials/circumstances. MCI and AD individuals did not differ in their level of memory complaints. Correlational analyses indicated that a higher level of memory complaints relative to conversations and to movies and books were associated with a higher level of objective cognitive deficits in persons with MCI but not in AD. Furthermore, complaints increased in parallel with global cognitive deficits in MCI. These results suggest that persons with MCI report more memory complaints than healthy older controls, but only in specific domains and circumstances, and that anosognosia is more characteristic of the demented than of the MCI phase of Alzheimer's disease.

  16. 6 CFR 13.6 - Prerequisites for issuing a Complaint.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Prerequisites for issuing a Complaint. 13.6 Section 13.6 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.6 Prerequisites for issuing a Complaint. (a) The Reviewing Official may issue...

  17. 77 FR 37558 - Disclosure of Certain Credit Card Complaint Data

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... database that, instead of aiding complainants, enables data mining and market research.\\12\\ The... PROTECTION 12 CFR Chapter X Disclosure of Certain Credit Card Complaint Data AGENCY: Bureau of Consumer... complaint data that do not include personally identifiable information. The Bureau receives credit...

  18. 12 CFR 268.106 - Dismissals of complaints.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... complainant is a party provided that at least 180 days have passed since the filing of the administrative... criteria set forth in Commission decisions, finds that the complaint is part of a clear pattern of misuse... discrimination. A clear pattern of misuse of the EEO process requires: (i) Evidence of multiple complaint...

  19. 29 CFR 1614.107 - Dismissals of complaints.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... is a party provided that at least 180 days have passed since the filing of the administrative... the criteria set forth in Commission decisions, finds that the complaint is part of a clear pattern of... discrimination. A clear pattern of misuse of the EEO process requires: (i) Evidence of multiple complaint...

  20. 29 CFR 1614.107 - Dismissals of complaints.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... is a party provided that at least 180 days have passed since the filing of the administrative... the criteria set forth in Commission decisions, finds that the complaint is part of a clear pattern of... discrimination. A clear pattern of misuse of the EEO process requires: (i) Evidence of multiple complaint...

  1. 32 CFR 513.2 - Administrative procedures for processing complaints.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Administrative procedures for processing... procedures for processing complaints. (a) Commander's actions. Upon receipt of a debt complaint, the... believed the creditor's debt processing privileges should be revoked, include a recommendation stating...

  2. Sleep Dysfunction and Gastrointestinal Diseases.

    PubMed

    Khanijow, Vikesh; Prakash, Pia; Emsellem, Helene A; Borum, Marie L; Doman, David B

    2015-12-01

    Sleep deprivation and impaired sleep quality have been associated with poor health outcomes. Many patients experience sleep disturbances, which can increase the risk of medical conditions such as hypertension, obesity, stroke, and heart disease as well as increase overall mortality. Recent studies have suggested that there is a strong association between sleep disturbances and gastrointestinal diseases. Proinflammatory cytokines, such as tumor necrosis factor, interleukin-1, and interleukin-6, have been associated with sleep dysfunction. Alterations in these cytokines have been seen in certain gastrointestinal diseases, such as gastroesophageal reflux disease, inflammatory bowel disease, liver disorders, and colorectal cancer. It is important for gastroenterologists to be aware of the relationship between sleep disorders and gastrointestinal illnesses to ensure good care for patients. This article reviews the current research on the interplay between sleep disorders, immune function, and gastrointestinal diseases. PMID:27134599

  3. Sleep Dysfunction and Gastrointestinal Diseases

    PubMed Central

    Khanijow, Vikesh; Prakash, Pia; Emsellem, Helene A.; Borum, Marie L.

    2015-01-01

    Sleep deprivation and impaired sleep quality have been associated with poor health outcomes. Many patients experience sleep disturbances, which can increase the risk of medical conditions such as hypertension, obesity, stroke, and heart disease as well as increase overall mortality. Recent studies have suggested that there is a strong association between sleep disturbances and gastrointestinal diseases. Proinflammatory cytokines, such as tumor necrosis factor, interleukin-1, and interleukin-6, have been associated with sleep dysfunction. Alterations in these cytokines have been seen in certain gastrointestinal diseases, such as gastroesophageal reflux disease, inflammatory bowel disease, liver disorders, and colorectal cancer. It is important for gastroenterologists to be aware of the relationship between sleep disorders and gastrointestinal illnesses to ensure good care for patients. This article reviews the current research on the interplay between sleep disorders, immune function, and gastrointestinal diseases. PMID:27134599

  4. The chicken gastrointestinal microbiome.

    PubMed

    Oakley, Brian B; Lillehoj, Hyun S; Kogut, Michael H; Kim, Woo K; Maurer, John J; Pedroso, Adriana; Lee, Margie D; Collett, Stephen R; Johnson, Timothy J; Cox, Nelson A

    2014-11-01

    The domestic chicken is a common model organism for human biological research and of course also forms the basis of a global protein industry. Recent methodological advances have spurred the recognition of microbiomes as complex communities with important influences on the health and disease status of the host. In this minireview, we provide an overview of the current state of knowledge of the chicken gastrointestinal microbiome focusing on spatial and temporal variability, the presence and importance of human pathogens, the influence of the microbiota on the immune system, and the importance of the microbiome for poultry nutrition. Review and meta-analysis of public data showed cecal communities dominated by Firmicutes and Bacteroides at the phylum level, while at finer levels of taxonomic resolution, a phylogenetically diverse assemblage of microorganisms appears to have similar metabolic functions that provide important benefits to the host as inferred from metagenomic data. This observation of functional redundancy may have important implications for management of the microbiome. We foresee advances in strategies to improve gut health in commercial operations through management of the intestinal microbiota as an alternative to in-feed subtherapeutic antibiotics, improvements in pre- and probiotics, improved management of polymicrobial poultry diseases, and better control of human pathogens via colonization reduction or competitive exclusion strategies. PMID:25263745

  5. The Gastrointestinal Microbiome

    PubMed Central

    Engen, Phillip A.; Green, Stefan J.; Voigt, Robin M.; Forsyth, Christopher B.; Keshavarzian, Ali

    2015-01-01

    The excessive use of alcohol is a global problem causing many adverse pathological health effects and a significant financial health care burden. This review addresses the effect of alcohol consumption on the microbiota in the gastrointestinal tract (GIT). Although data are limited in humans, studies highlight the importance of changes in the intestinal microbiota in alcohol-related disorders. Alcohol-induced changes in the GIT microbiota composition and metabolic function may contribute to the well-established link between alcohol-induced oxidative stress, intestinal hyperpermeability to luminal bacterial products, and the subsequent development of alcoholic liver disease (ALD), as well as other diseases. In addition, clinical and preclinical data suggest that alcohol-related disorders are associated with quantitative and qualitative dysbiotic changes in the intestinal microbiota and may be associated with increased GIT inflammation, intestinal hyperpermeability resulting in endotoxemia, systemic inflammation, and tissue damage/organ pathologies including ALD. Thus, gut-directed interventions, such as probiotic and synbiotic modulation of the intestinal microbiota, should be considered and evaluated for prevention and treatment of alcohol-associated pathologies. PMID:26695747

  6. Thalidomide in gastrointestinal disorders.

    PubMed

    Bousvaros, A; Mueller, B

    2001-01-01

    Thalidomide was originally marketed as a sedative, but was removed from the market in 1961 after it was associated with an epidemic of severe birth defects. Subsequently, it has been shown to have therapeutic efficacy in a number of the gastrointestinal tract conditions characterised by immune dysregulation. The exact mechanism of the immunosuppressive effects of thalidomide is unknown; proposed mechanisms include inhibition of tumour necrosis factor alpha release and inhibition of angiogenesis. In chronic graft versus host disease, use of high dose thalidomide (1200 mg/day) may bring about a response in 20% of patients with refractory disease. Thalidomide 200 mg/day helps eradicate ulcers in 50% of patients with HIV-associated oral aphthous ulceration. In Behçet's disease, thalidomide 100 to 300 mg/day can decrease the number of mucocutaneous ulcers, although full remission occurs in less than 20% of patients. In Crohn's disease, thalidomide 50 to 300 mg/day may decrease the severity of mucosal disease and prompt closure of fistulae. Patients to be placed on thalidomide therapy must practice either abstinence or strict birth control; women must undergo regular pregnancy testing and utilise 2 forms of contraception. Other adverse effects include sedation (present in nearly all patients), symptomatic neuropathy (present in approximately 20%), and skin rashes. Given the potential toxicity, thalidomide use should generally be limited to clinical protocols with institutional review board oversight.

  7. [Functional gastrointestinal disorders].

    PubMed

    Vogt, W

    2007-11-21

    Functional gastrointestinal disorders particularly dyspepsia an irritable bowel syndrome are frequent problems for the general practitioner and also for the specialist. Both are diseases and not only a kind of discomfort. The high frequency of dispepsia and irritable bowel syndrome induces very high direct and indirect charges. Both diseases depend on a number of factors or causes, for whom the evidence is not good. But there are good experimental data for the visceral hypersensitivity as one of the main factors. Gastroscopy is the most important examination in the diagnosis of dyspepsia. Endoscopy has to be done in all patients with alarm symptoms an in all patients older than 45 years. The therapy of dyspepsia is an empirical one. The eradication of Helicobacter pylori is a therapeutical option, but only 8% of the patients will have benefit for a long time. Other therapeutical options are the use of proton-pump inhibitors, prokinetics or phytotherapeutics. The therapy of the irritable bowel syndrome depends on the subtype of the disease (diarrhea, constipation, abdominal pain, bloating). First of all a good doctor-patient relationship is mandatory. Furthermore the use of dietary fibre, antidiarrhoeics, laxatives and muscle relaxants may be beneficial. And phytotherapeutics can be an additional therapeutic approach.

  8. Feline gastrointestinal microbiota.

    PubMed

    Minamoto, Yasushi; Hooda, Seema; Swanson, Kelly S; Suchodolski, Jan S

    2012-06-01

    The close relationship between gastrointestinal (GI) microbiota and its host has an impact on the health status of an animal that reaches beyond the GI tract. A balanced microbiome stimulates the immune system, aids in the competitive exclusion of transient pathogens and provides nutritional benefits to the host. With recent rapid advances in high-throughput sequencing technology, molecular approaches have become the routinely used tools for ecological studies of the feline microbiome, and have revealed a highly diverse and complex intestinal ecosystem in the feline GI tract. The major bacterial groups are similar to those found in other mammals, with Firmicutes, Bacteroidetes, Actinobacteria and Proteobacteria constituting more than 99% of intestinal microbiota. Several nutritional studies have demonstrated that the feline microbiota can be modulated by the amount of soluble fibers (i.e., prebiotics) and macronutrients (i.e., protein content) in the diet. Initial clinical studies have suggested the presence of a dysbiosis in feline inflammatory bowel disease (IBD). Recently, metagenomic approaches have attempted to characterize the microbial gene pool. However, more studies are needed to describe the phylogenetic and functional changes in the intestinal microbiome in disease states and in response to environmental and dietary modulations. This paper reviews recent studies cataloging the microbial phylotypes in the GI tract of cats.

  9. The chicken gastrointestinal microbiome.

    PubMed

    Oakley, Brian B; Lillehoj, Hyun S; Kogut, Michael H; Kim, Woo K; Maurer, John J; Pedroso, Adriana; Lee, Margie D; Collett, Stephen R; Johnson, Timothy J; Cox, Nelson A

    2014-11-01

    The domestic chicken is a common model organism for human biological research and of course also forms the basis of a global protein industry. Recent methodological advances have spurred the recognition of microbiomes as complex communities with important influences on the health and disease status of the host. In this minireview, we provide an overview of the current state of knowledge of the chicken gastrointestinal microbiome focusing on spatial and temporal variability, the presence and importance of human pathogens, the influence of the microbiota on the immune system, and the importance of the microbiome for poultry nutrition. Review and meta-analysis of public data showed cecal communities dominated by Firmicutes and Bacteroides at the phylum level, while at finer levels of taxonomic resolution, a phylogenetically diverse assemblage of microorganisms appears to have similar metabolic functions that provide important benefits to the host as inferred from metagenomic data. This observation of functional redundancy may have important implications for management of the microbiome. We foresee advances in strategies to improve gut health in commercial operations through management of the intestinal microbiota as an alternative to in-feed subtherapeutic antibiotics, improvements in pre- and probiotics, improved management of polymicrobial poultry diseases, and better control of human pathogens via colonization reduction or competitive exclusion strategies.

  10. [Complaint to the disciplinary board about a resident].

    PubMed

    Linthorst, Gabor E; Lauw, Fanny N; Hanekamp, Lilian A; Hoekstra, Joost B L

    2014-01-01

    We describe the course of two complaints that were filed by patients to the Dutch Medical Disciplinary Board against two internal medicine residents. In the procedure following the complaints the supervisor and the teacher were actively involved, which resulted in one complaint being dropped. We describe the importance of adequate moral support in such cases, as the complaint may lead to loss of work satisfaction or self-esteem, especially for those in training. We make some recommendations on how the resident and the supervisor/head of the department should engage in complaints filed to the Medical Disciplinary Board. In addition, we suggest that routine 'error-meetings' may help to provide an open atmosphere where disclosure of errors and the various procedures at the hospital or disciplinary boards are promoted.

  11. Focal brain atrophy in gastric bypass patients with cognitive complaints.

    PubMed

    Graff-Radford, Jonathan; Whitwell, Jennifer L; Trenerry, Max R; Ahlskog, J Eric; Jensen, Michael D; Jack, Clifford R; Josephs, Keith A

    2011-12-01

    Recently, we have identified a series of patients presenting with cognitive complaints after gastric bypass, without any identifiable etiology. We aimed to determine if focal brain atrophy could account for the complaints. A retrospective case series was performed to identify patients with cognitive complaints following gastric bypass who had a volumetric MRI. Voxel-based morphometry was used to assess patterns of grey matter loss in all 10 patients identified, compared to 10 age and gender-matched controls. All patients had undergone Roux-en-Y gastric bypass surgery at a median age of 54 (range: 46-64). Cognitive complaints developed at a median age of 57 (52-69). Formal neuropsychometric testing revealed only minor deficits. No nutritional abnormalities were identified. Voxel-based morphometry demonstrated focal thalamic atrophy in the gastric bypass patients when compared to controls. Patients with cognitive complaints after gastric bypass surgery may have focal thalamic brain atrophy that could result in cognitive impairment.

  12. 34 CFR 300.140 - Due process complaints and State complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... (b) Child find complaints—to be filed with the LEA in which the private school is located. (1) The... filed with the LEA in which the private school is located and a copy must be forwarded to the SEA. (c... §§ 300.151 through 300.153. (2) A complaint filed by a private school official under § 300.136(a) must...

  13. Subjective cognitive complaints and mortality: does the type of complaint matter?

    PubMed

    Singh-Manoux, Archana; Dugravot, Aline; Ankri, Joel; Nabi, Hermann; Berr, Claudine; Goldberg, Marcel; Zins, Marie; Kivimaki, Mika; Elbaz, Alexis

    2014-01-01

    Middle-aged subjects report subjective cognitive complaints (SSCs) but whether these are meaningfully related to health remains unknown. We examined the association between SCCs, both amnestic and non-amnestic, and mortality in a middle-aged population after taking into account the role of depression. 15,510 participants (26.2% women), mean age 57.9 years in 2002, from the French GAZEL study provided data on 3 measures of SCCs: memory complaints, cognitive symptoms (forgetfulness, difficulties in recalling memories, retaining new information, mental calculation, in language, and orientation) and whether they sought medical advice for SCCs. All-cause mortality was assessed between 2002 and 2012. Over the follow-up 56.3% participants reported memory problems, 62.6% cognitive complaints, 22.3% sought medical advice and 651 died. All SCCs were strongly associated (odds ratio 2.08-6.35) with depression which was itself associated with greater mortality (HR = 1.77, 95% CI: 1.50, 2.09). In analyses adjusted for age, sex, education, marital status and depression difficulty in mental calculation (HR = 1.30, 95% CI: 1.08, 1.60) and seeking medical advice for cognitive symptoms (HR = 1.41, 95% CI: 1.18, 1.68) were significantly associated with mortality, while memory complaints did not carry increased risk (HR = 0.93, 95% CI: 0.79, 1.09). All SCCS were strongly associated with depression but not all carried excess risk of mortality. PMID:24161314

  14. Role of a health psychologist in the management of functional esophageal complaints.

    PubMed

    Riehl, M E; Kinsinger, S; Kahrilas, P J; Pandolfino, J E; Keefer, L

    2015-07-01

    Upper gastrointestinal complaints are common among patients in a gastrointestinal clinic. Outside of typical gastroesophageal reflux disease symptoms that are treated with medication, the symptom presentations of esophageal patients, particularly those with functional conditions, are often difficult to treat and account for high health-care utilization. This manuscript describes the role of a health psychologist in the treatment of esophageal disorders using behavioral medicine interventions. Observations over the course of a 1-year period indicate that the sample presents with a relatively low level of psychological distress but reports negative effects of their symptoms on health-related quality of life. Five case examples of commonly treated disorders (globus, non-cardiac chest pain, functional dysphagia, rumination syndrome, supragastric belching) are described to highlight how behavioral treatment can improve patients' symptoms, decrease health-care utilization, and improve overall quality of life in a timely and relatively simple manner. Successful treatment outcomes are associated with a collaborative working alliance between patient, health psychologist, and gastroenterologist. Results indicate the benefit of referring appropriate esophageal patients to a health psychologist with specialization in gastroenterology. PMID:26174953

  15. Reproducible research in vadose zone sciences

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A significant portion of present-day soil and Earth science research is computational, involving complex data analysis pipelines, advanced mathematical and statistical models, and sophisticated computer codes. Opportunities for scientific progress are greatly diminished if reproducing and building o...

  16. Thou Shalt Be Reproducible! A Technology Perspective

    PubMed Central

    Mair, Patrick

    2016-01-01

    This article elaborates on reproducibility in psychology from a technological viewpoint. Modern open source computational environments are shown and explained that foster reproducibility throughout the whole research life cycle, and to which emerging psychology researchers should be sensitized, are shown and explained. First, data archiving platforms that make datasets publicly available are presented. Second, R is advocated as the data-analytic lingua franca in psychology for achieving reproducible statistical analysis. Third, dynamic report generation environments for writing reproducible manuscripts that integrate text, data analysis, and statistical outputs such as figures and tables in a single document are described. Supplementary materials are provided in order to get the reader started with these technologies. PMID:27471486

  17. Reproducibility and uncertainty of wastewater turbidity measurements.

    PubMed

    Joannis, C; Ruban, G; Gromaire, M-C; Chebbo, G; Bertrand-Krajewski, J-L; Joannis, C; Ruban, G

    2008-01-01

    Turbidity monitoring is a valuable tool for operating sewer systems, but it is often considered as a somewhat tricky parameter for assessing water quality, because measured values depend on the model of sensor, and even on the operator. This paper details the main components of the uncertainty in turbidity measurements with a special focus on reproducibility, and provides guidelines for improving the reproducibility of measurements in wastewater relying on proper calibration procedures. Calibration appears to be the main source of uncertainties, and proper procedures must account for uncertainties in standard solutions as well as non linearity of the calibration curve. With such procedures, uncertainty and reproducibility of field measurement can be kept lower than 5% or 25 FAU. On the other hand, reproducibility has no meaning if different measuring principles (attenuation vs. nephelometry) or very different wavelengths are used.

  18. Thou Shalt Be Reproducible! A Technology Perspective.

    PubMed

    Mair, Patrick

    2016-01-01

    This article elaborates on reproducibility in psychology from a technological viewpoint. Modern open source computational environments are shown and explained that foster reproducibility throughout the whole research life cycle, and to which emerging psychology researchers should be sensitized, are shown and explained. First, data archiving platforms that make datasets publicly available are presented. Second, R is advocated as the data-analytic lingua franca in psychology for achieving reproducible statistical analysis. Third, dynamic report generation environments for writing reproducible manuscripts that integrate text, data analysis, and statistical outputs such as figures and tables in a single document are described. Supplementary materials are provided in order to get the reader started with these technologies. PMID:27471486

  19. 76 FR 78042 - Certain Silicon Microphone Packages and Products Containing Same Receipt of Complaint...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-15

    ... COMMISSION Certain Silicon Microphone Packages and Products Containing Same Receipt of Complaint... complaint entitled In Re Certain Silicon Microphone Packages and Products Containing Same, DN 2864; the... importation of certain silicon microphone packages and products containing same. The complaint names...

  20. 77 FR 18860 - Certain Consumer Electronics, Including Mobile Phones and Tablets; Notice of Receipt of Complaint...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... COMMISSION Certain Consumer Electronics, Including Mobile Phones and Tablets; Notice of Receipt of Complaint... complaint entitled Certain Consumer Electronics, Including Mobile Phones and Tablets, DN 2885; the... importation of certain consumer electronics, including mobile phones and tablets. The complaint names...

  1. 76 FR 38743 - Proposed Information Collection (Complaint of Employment Discrimination) Activity: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... AFFAIRS Proposed Information Collection (Complaint of Employment Discrimination) Activity: Comment Request... solicits comments on information needed to process a complaint of employment discrimination. DATES: Written... techniques or the use of other forms of information technology. Title: Complaint of Employment...

  2. An insight into the gastrointestinal component of fibromyalgia: clinical manifestations and potential underlying mechanisms.

    PubMed

    Slim, Mahmoud; Calandre, Elena Pita; Rico-Villademoros, Fernando

    2015-03-01

    Fibromyalgia syndrome is characterized by chronic generalized pain accompanied by a broad symptomatologic spectrum. Besides chronic fatigue, sleep disturbances, headaches and cognitive dysfunction that are extensively described in the literature, a considerable proportion of patients with fibromyalgia experience gastrointestinal symptoms that are commonly overlooked in the studies that are not specifically dedicated to evaluate these manifestations. Nevertheless, various attempts were undertaken to explore the gastrointestinal dimension of fibromyalgia. Several studies have demonstrated an elevated comorbidity of irritable bowel syndrome (IBS) among patients with fibromyalgia. Other studies have investigated the frequency of presentation of gastrointestinal symptoms in fibromyalgia in a nonspecific approach describing several gastrointestinal complaints frequently reported by these patients such as abdominal pain, dyspepsia and bowel changes, among others. Several underlying mechanisms that require further investigation could serve as potential explanatory hypotheses for the appearance of such manifestations. These include sensitivity to dietary constituents such as gluten, lactose or FODMAPs or alterations in the brain-gut axis as a result of small intestinal bacterial overgrowth or subclinical enteric infections such as giardiasis. The gastrointestinal component of fibromyalgia constitutes a relevant element of the multidisciplinary pathophysiologic mechanisms underlying fibromyalgia that need to be unveiled, as this would contribute to the adequate designation of relevant treatment alternatives corresponding to these manifestations.

  3. An insight into the gastrointestinal component of fibromyalgia: clinical manifestations and potential underlying mechanisms.

    PubMed

    Slim, Mahmoud; Calandre, Elena Pita; Rico-Villademoros, Fernando

    2015-03-01

    Fibromyalgia syndrome is characterized by chronic generalized pain accompanied by a broad symptomatologic spectrum. Besides chronic fatigue, sleep disturbances, headaches and cognitive dysfunction that are extensively described in the literature, a considerable proportion of patients with fibromyalgia experience gastrointestinal symptoms that are commonly overlooked in the studies that are not specifically dedicated to evaluate these manifestations. Nevertheless, various attempts were undertaken to explore the gastrointestinal dimension of fibromyalgia. Several studies have demonstrated an elevated comorbidity of irritable bowel syndrome (IBS) among patients with fibromyalgia. Other studies have investigated the frequency of presentation of gastrointestinal symptoms in fibromyalgia in a nonspecific approach describing several gastrointestinal complaints frequently reported by these patients such as abdominal pain, dyspepsia and bowel changes, among others. Several underlying mechanisms that require further investigation could serve as potential explanatory hypotheses for the appearance of such manifestations. These include sensitivity to dietary constituents such as gluten, lactose or FODMAPs or alterations in the brain-gut axis as a result of small intestinal bacterial overgrowth or subclinical enteric infections such as giardiasis. The gastrointestinal component of fibromyalgia constitutes a relevant element of the multidisciplinary pathophysiologic mechanisms underlying fibromyalgia that need to be unveiled, as this would contribute to the adequate designation of relevant treatment alternatives corresponding to these manifestations. PMID:25119830

  4. Primary gastrointestinal lymphomas.

    PubMed

    Cooper, D L; Doria, R; Salloum, E

    1996-03-01

    Recent evidence suggests that a significant proportion of primary gastrointestinal lymphomas are driven by exogenous agents/antigens. In the stomach, Helicobacter pylori appears to be responsible for most cases of low-grade lymphomas (MALToma), whereas an infectious etiology is suspected in immunoproliferative small intestine disease (IPSID). Similarly, enteropathy-associated T-cell lymphomas appear to result from a disordered response to gluten, although this profile remains controversial. Accordingly, although traditional antineoplastic treatments, such as surgery and radiation, are still important for the treatment of primary GI lymphomas, antibiotics may be the first line of therapy for low-grade gastric MALToma, and they are often used alone or in combination with chemotherapy for IPSID. In patients with celiac sprue, a gluten-free diet appears to markedly reduce the risk for lymphoma. An important caveat for the treatment of gastric lymphomas is that only low-grade gastric MALTomas have consistently responded to antibiotics. Treatment of high-grade gastric lymphoma is evolving. Although surgery was once considered central to diagnosis, staging, and treatment of gastric lymphoma, most patients can now have a diagnosis established by endoscopic biopsy and are candidates for chemotherapy and adjuvant radiation. The risks of fatal hemorrhage and perforation have probably been vastly overestimated and appear to be equal or less than the mortality associated with surgery. In addition, the long-term effects of gastric resection on quality of life have been almost completely ignored. Systemic lymphomas involve the GI tract far more often than is clinically apparent. In most cases, treatment should not be affected.

  5. Surveillance for gastrointestinal malignancies

    PubMed Central

    Tiwari, Ashish K; Laird-Fick, Heather S; Wali, Ramesh K; Roy, Hemant K

    2012-01-01

    Gastrointestinal (GI) malignancies are notorious for frequently progressing to advanced stages even in the absence of serious symptoms, thus leading to delayed diagnoses and dismal prognoses. Secondary prevention of GI malignancies through early detection and treatment of cancer-precursor/premalignant lesions, therefore, is recognized as an effective cancer prevention strategy. In order to efficiently detect these lesions, systemic application of screening tests (surveillance) is needed. However, most of the currently used non-invasive screening tests for GI malignancies (for example, serum markers such as alpha-fetoprotein for hepatocellular carcinoma, and fecal occult blood test, for colon cancer) are only modestly effective necessitating the use of highly invasive endoscopy-based procedures, such as esophagogastroduodenoscopy and colonoscopy for screening purposes. Even for hepatocellular carcinoma where non-invasive imaging (ultrasonography) has become a standard screening tool, the need for repeated liver biopsies of suspicious liver nodules for histopathological confirmation can’t be avoided. The invasive nature and high-cost associated with these screening tools hinders implementation of GI cancer screening programs. Moreover, only a small fraction of general population is truly predisposed to developing GI malignancies, and indeed needs surveillance. To spare the average-risk individuals from superfluous invasive procedures and achieve an economically viable model of cancer prevention, it’s important to identify cohorts in general population that are at substantially high risk of developing GI malignancies (risk-stratification), and select suitable screening tests for surveillance in these cohorts. We herein provide a brief overview of such high-risk cohorts for different GI malignancies, and the screening strategies that have commonly been employed for surveillance purpose in them. PMID:22969223

  6. 76 FR 32372 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-06

    .... International Trade Commission has received a complaint entitled In the Matter of Certain Microprocessors... certain microprocessors, components thereof, and products containing same. The complaint names...

  7. 76 FR 35238 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-16

    .... International Trade Commission has received a complaint entitled In Re Static Random Access Memories and... static random access memories and products containing same. The complaint names as respondents...

  8. 77 FR 59003 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-25

    .... International Trade Commission has received a complaint entitled Certain Integrated Circuit Chips and Products... integrated circuit chips and products containing the same. The complaint names as respondents LSI...

  9. 77 FR 10556 - Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ... Trade Commission has received a complaint entitled Certain Radio Frequency Integrated Circuits and... importation of certain radio frequency integrated circuits and devices containing same. The complaint names...

  10. 77 FR 29689 - Receipt of Amended Complaint; Solicitation of Comments Relating to the Public Interest

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ... Trade Commission has received an amended complaint entitled Certain Radio Frequency Integrated Circuits... importation of certain radio frequency integrated circuits and devices containing same. The complaint names...

  11. 76 FR 18246 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    .... International Trade Commission has received a complaint entitled In Re Certain Handheld Electronic Computing... handheld electronic computing devices, related software, and components thereof. The complaint names...

  12. 75 FR 54910 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    .... International Trade Commission has received a complaint entitled In Re Certain Ground Fault Circuit Interrupters... ground fault circuit interrupters and products containing same. The complaint names as respondents...

  13. 76 FR 32987 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    .... International Trade Commission has received a complaint entitled In Re Certain Liquid Crystal Display Devices... liquid crystal display devices and products containing same. The complaint names as respondents...

  14. Assessing the reproducibility of discriminant function analyses.

    PubMed

    Andrew, Rose L; Albert, Arianne Y K; Renaut, Sebastien; Rennison, Diana J; Bock, Dan G; Vines, Tim

    2015-01-01

    Data are the foundation of empirical research, yet all too often the datasets underlying published papers are unavailable, incorrect, or poorly curated. This is a serious issue, because future researchers are then unable to validate published results or reuse data to explore new ideas and hypotheses. Even if data files are securely stored and accessible, they must also be accompanied by accurate labels and identifiers. To assess how often problems with metadata or data curation affect the reproducibility of published results, we attempted to reproduce Discriminant Function Analyses (DFAs) from the field of organismal biology. DFA is a commonly used statistical analysis that has changed little since its inception almost eight decades ago, and therefore provides an opportunity to test reproducibility among datasets of varying ages. Out of 100 papers we initially surveyed, fourteen were excluded because they did not present the common types of quantitative result from their DFA or gave insufficient details of their DFA. Of the remaining 86 datasets, there were 15 cases for which we were unable to confidently relate the dataset we received to the one used in the published analysis. The reasons ranged from incomprehensible or absent variable labels, the DFA being performed on an unspecified subset of the data, or the dataset we received being incomplete. We focused on reproducing three common summary statistics from DFAs: the percent variance explained, the percentage correctly assigned and the largest discriminant function coefficient. The reproducibility of the first two was fairly high (20 of 26, and 44 of 60 datasets, respectively), whereas our success rate with the discriminant function coefficients was lower (15 of 26 datasets). When considering all three summary statistics, we were able to completely reproduce 46 (65%) of 71 datasets. While our results show that a majority of studies are reproducible, they highlight the fact that many studies still are not the

  15. Assessing the reproducibility of discriminant function analyses

    PubMed Central

    Andrew, Rose L.; Albert, Arianne Y.K.; Renaut, Sebastien; Rennison, Diana J.; Bock, Dan G.

    2015-01-01

    Data are the foundation of empirical research, yet all too often the datasets underlying published papers are unavailable, incorrect, or poorly curated. This is a serious issue, because future researchers are then unable to validate published results or reuse data to explore new ideas and hypotheses. Even if data files are securely stored and accessible, they must also be accompanied by accurate labels and identifiers. To assess how often problems with metadata or data curation affect the reproducibility of published results, we attempted to reproduce Discriminant Function Analyses (DFAs) from the field of organismal biology. DFA is a commonly used statistical analysis that has changed little since its inception almost eight decades ago, and therefore provides an opportunity to test reproducibility among datasets of varying ages. Out of 100 papers we initially surveyed, fourteen were excluded because they did not present the common types of quantitative result from their DFA or gave insufficient details of their DFA. Of the remaining 86 datasets, there were 15 cases for which we were unable to confidently relate the dataset we received to the one used in the published analysis. The reasons ranged from incomprehensible or absent variable labels, the DFA being performed on an unspecified subset of the data, or the dataset we received being incomplete. We focused on reproducing three common summary statistics from DFAs: the percent variance explained, the percentage correctly assigned and the largest discriminant function coefficient. The reproducibility of the first two was fairly high (20 of 26, and 44 of 60 datasets, respectively), whereas our success rate with the discriminant function coefficients was lower (15 of 26 datasets). When considering all three summary statistics, we were able to completely reproduce 46 (65%) of 71 datasets. While our results show that a majority of studies are reproducible, they highlight the fact that many studies still are not the

  16. Primary Gastrointestinal Lymphoma

    PubMed Central

    Chen, Yinting; Chen, Yanzhu; Chen, Shaojie; Wu, Lili; Xu, Lishu; Lian, Guoda; Yang, Kege; Li, Yaqing; Zeng, Linjuan; Huang, Kaihong

    2015-01-01

    Abstract Primary gastrointestinal lymphoma (PGIL) is a rare malignant tumor without standard diagnosis and treatment methods. This study is aimed to systematically analyze its clinical characteristics and draw out an appropriate flow chart of diagnosis and treatment process for PGIL in China. This study retrospectively analyzed the clinicopathological characteristics, diagnostic approaches, prognostic factors, and therapeutic modalities in 415 cases of PGIL in Chinese province of Guangdong. A systematic review was conducted in 118 studies containing 5075 patients to further identify clinical manifestations and mortalities of therapeutic modalities. The most common clinical presentations were abdominal pain and bloody stools. Endoscopic biopsy was an important diagnostic means, and usually more than once to make a definite diagnosis. Retrospective multicenter clinical study showed that younger onset age (<60 years), female, one region involved, one lesion, early stage, International Prognostic Index (IPI ≤1), normal lactate dehydrogenase (LDH), normal albumin, and nonemergency operation were significant prognostic factors for B-cell lymphoma; non-B symptom, tumor restricted to gastric or ileocecal region, one lesion, performance status (PS ≤1), normal LDH, and nonsurgery alone were significant prognostic factors for T-cell lymphoma. Site of origin and IPI were independent prognostic factors for B-cell lymphoma; PS was the independent prognostic factor for T-cell lymphoma. And T-cell lymphoma had worse overall survival (OS) and progression-free survival (PFS) than B-cell lymphoma. Among different therapeutic modalities, chemotherapy alone or combined with surgery showed better OS and PFS than surgery alone for diffuse large B-cell lymphoma (DLBCL) of stage I/II E and T-cell lymphoma. For DLBCL of stage III E/IV and mucosa-associated lymphoid tissue lymphoma, OS and PFS did not differ among different therapeutic groups. In meta-analysis, surgery plus chemotherapy

  17. The employee who complains. Understanding and responding to staff complaints.

    PubMed

    Davidhizar, R

    1991-01-01

    A manager's mood sets the tone for the work environment and should be a positive role model. When employees complain, the manager should listen and make careful note not only of the content of what is expressed but also of the feelings behind the message. In short, the manager should address the dynamics behind the complaint in order to be able to appropriately receive, investigate, and respond to complaints. It is the wise manager who accepts that complaints are an inevitable part of the managerial role and who works to develop expertise in ways of handling this human reaction.

  18. Gastrointestinal Amyloidosis Presenting with Multiple Episodes of Gastrointestinal Bleeding

    SciTech Connect

    Kim, Sang Hyeon Kang, Eun Ju; Park, Jee Won; Jo, Jung Hyun; Kim, Soo Jin; Cho, Jin Han; Kang, Myong Jin; Park, Byeong Ho

    2009-05-15

    Amyloidosis is characterized by the extracellular deposition of amyloid protein in various organs. Gastrointestinal involvement in amyloidosis is common, but a diagnosis of amyloidosis is often delayed. Severe gastrointestinal hemorrhage in amyloidosis is rare but can be fatal in some cases. We experienced a case of a 49-year-old man who presented with recurrent massive hematochezia. Although embolization was performed eight times for bleeding from different sites of the small intestine, hematochezia did not cease. We report the case, with a review of the literature.

  19. Relevance relations for the concept of reproducibility

    PubMed Central

    Atmanspacher, H.; Bezzola Lambert, L.; Folkers, G.; Schubiger, P. A.

    2014-01-01

    The concept of reproducibility is widely considered a cornerstone of scientific methodology. However, recent problems with the reproducibility of empirical results in large-scale systems and in biomedical research have cast doubts on its universal and rigid applicability beyond the so-called basic sciences. Reproducibility is a particularly difficult issue in interdisciplinary work where the results to be reproduced typically refer to different levels of description of the system considered. In such cases, it is mandatory to distinguish between more and less relevant features, attributes or observables of the system, depending on the level at which they are described. For this reason, we propose a scheme for a general ‘relation of relevance’ between the level of complexity at which a system is considered and the granularity of its description. This relation implies relevance criteria for particular selected aspects of a system and its description, which can be operationally implemented by an interlevel relation called ‘contextual emergence’. It yields a formally sound and empirically applicable procedure to translate between descriptive levels and thus construct level-specific criteria for reproducibility in an overall consistent fashion. Relevance relations merged with contextual emergence challenge the old idea of one fundamental ontology from which everything else derives. At the same time, our proposal is specific enough to resist the backlash into a relativist patchwork of unconnected model fragments. PMID:24554574

  20. Reproducibility responsibilities in the HPC arena

    SciTech Connect

    Fahey, Mark R; McLay, Robert

    2014-01-01

    Expecting bit-for-bit reproducibility in the HPC arena is not feasible because of the ever changing hardware and software. No user s application is an island; it lives in an HPC eco-system that changes over time. Old hardware stops working and even old software won t run on new hardware. Further, software libraries change over time either by changing the internals or even interfaces. So bit-for-bit reproducibility should not be expected. Rather a reasonable expectation is that results are reproducible within error bounds; or that the answers are close (which is its own debate.) To expect a researcher to reproduce their own results or the results of others within some error bounds, there must be enough information to recreate all the details of the experiment. This requires complete documentation of all phases of the researcher s workflow; from code to versioning to programming and runtime environments to publishing of data. This argument is the core statement of the Yale 2009 Declaration on Reproducible Research [1]. Although the HPC ecosystem is often outside the researchers control, the application code could be built almost identically and there is a chance for very similar results with just only round-off error differences. To achieve complete documentation at every step, the researcher, the computing center, and the funding agencies all have a role. In this thesis, the role of the researcher is expanded upon as compared to the Yale report and the role of the computing centers is described.

  1. [CLINICAL INVESTIGATION OF AN EXCESSIVE SLEEPINESS COMPLAINT].

    PubMed

    Evangelista, Elisa; Barateau, Lucie; Dauvilliers, Yves

    2016-06-01

    Excessive sleepiness is a common problem, defined by a complaint of excessive daytime sleepiness almost daily with an inability to stay awake and alert dosing periods at sleep, with episodes of irresistible sleep need or drowsiness or non-intentional sleep, or by a night's sleep time overly extended often associated with sleep inertia. This sleepiness is variable in terms of phenotype and severity to be specified by the out-patient clinic. It is considered to be chronic beyond three months and often responsible for significant functional impairment of school and professional performance, of the accidents and cardiovascular risk. We need to decipher the causes of excessive sleepiness: sleep deprivation, toxic and iatrogenic, psychiatric disorders (including depression), non-psychiatric medical problems (obesity, neurological pathologies...), sleep disorders (as for example the sleep apnea syndrome), and finally the central hypersomnias namely narcolepsy type 1 and 2, idiopathic hypersomnia, and Kleine-Levin syndrome. If careful questioning often towards one of these etiologies, need most of the time a paraclinical balance with a sleep recording to confirm the diagnosis. Patients affected with potential central hypersomnia must be referred to the Sleep Study Centers that have the skills and the appropriate means to achieve this balance sheet. PMID:27538325

  2. Preprocedural considerations in gastrointestinal endoscopy.

    PubMed

    Gorospe, Emmanuel C; Oxentenko, Amy S

    2013-09-01

    The current practice of open-access endoscopy allows primary care and other non-gastroenterology physicians to directly refer patients for routine gastrointestinal endoscopic procedures. Open-access endoscopy is considered to be more cost-effective and time efficient than the traditional practice of referring patients for preprocedural consultation with a gastrointestinal endoscopist. Several studies have evaluated the performance of endoscopic procedures in an open-access environment and the utility of structured referral mechanisms to ensure safe and appropriately indicated procedures. This review focuses on 4 common preprocedural issues in gastrointestinal endoscopy encountered by primary care physicians: management of anticoagulation and antiplatelet therapy, indication for prophylactic antibiotic drug therapy, need for anesthesia-assisted sedation, and management of poor bowel preparation. We summarize the current guidelines that address these 4 common preprocedural issues to facilitate safe and clinically appropriate procedures in open-access endoscopy.

  3. Reproducible measurements of MPI performance characteristics.

    SciTech Connect

    Gropp, W.; Lusk, E.

    1999-06-25

    In this paper we describe the difficulties inherent in making accurate, reproducible measurements of message-passing performance. We describe some of the mistakes often made in attempting such measurements and the consequences of such mistakes. We describe mpptest, a suite of performance measurement programs developed at Argonne National Laboratory, that attempts to avoid such mistakes and obtain reproducible measures of MPI performance that can be useful to both MPI implementers and MPI application writers. We include a number of illustrative examples of its use.

  4. The Economics of Reproducibility in Preclinical Research

    PubMed Central

    Freedman, Leonard P.; Cockburn, Iain M.; Simcoe, Timothy S.

    2015-01-01

    Low reproducibility rates within life science research undermine cumulative knowledge production and contribute to both delays and costs of therapeutic drug development. An analysis of past studies indicates that the cumulative (total) prevalence of irreproducible preclinical research exceeds 50%, resulting in approximately US$28,000,000,000 (US$28B)/year spent on preclinical research that is not reproducible—in the United States alone. We outline a framework for solutions and a plan for long-term improvements in reproducibility rates that will help to accelerate the discovery of life-saving therapies and cures. PMID:26057340

  5. Isolated Splenic Vein Thrombosis: 8-Year-Old Boy with Massive Upper Gastrointestinal Bleeding and Hypersplenism.

    PubMed

    Kiani, Mohammad Ali; Forouzan, Arash; Masoumi, Kambiz; Mazdaee, Behnaz; Bahadoram, Mohammad; Kianifar, Hamid Reza; Ravari, Hassan

    2015-01-01

    We present an 8-year-old boy who was referred to our center with the complaint of upper gastrointestinal bleeding and was diagnosed with hypersplenism and progressive esophageal varices. Performing a computerized tomography (CT) scan, we discovered a suspicious finding in the venography phase in favor of thrombosis in the splenic vein. Once complementary examinations were done and due to recurrent bleeding and band ligation failure, the patient underwent splenectomy. And during the one-year follow-up obvious improvement of the esophageal varices was observed in endoscopy.

  6. Gastrointestinal manifestations as initial presenting features in a 40 years old woman with systemic lupus erythematosus.

    PubMed

    Ahmed, Q M; Arafat, S M; Azad, A K; Chowdhury, M J; Hasan, M K; Ahmed, F; Ananna, M A

    2015-01-01

    Gastrointestinal (GI) symptoms are common in patients with systemic lupus erythematosus (SLE). These symptoms can be due to primary GI disorders like peptic ulcer disease, pancreatitis or intestinal obstruction. But they can be due to SLE itself or complications of treatment of SLE. In this case report, we describe a 40 years old woman who presented initially with GI complaints. Later she was diagnosed as a case of SLE with chronic intestinal pseudo-obstruction (CIPO). The problems related to diagnosis and management is also discussed. PMID:25725689

  7. Nutritional support and gastrointestinal disease.

    PubMed

    Hennessy, K

    1989-06-01

    The use of nutritional support in patients with acute gastrointestinal disease requires a thorough knowledge of the pathophysiology and nutritional alterations that are caused by the disease process. Although nutritional therapy of a patient with gastrointestinal disease is not curative of the underlying disease, it does provide essential support to the patient, which improves response to, and eventual recovery from, illness. Special considerations need to be made to avoid complicating the patient's condition by inappropriate use of nutritional support solutions, which can lead to abnormal liver function. PMID:2498848

  8. Blood thinners and gastrointestinal endoscopy

    PubMed Central

    Ahmed, Monjur

    2016-01-01

    As the number of diagnostic and therapeutic gastrointestinal endoscopies is increasing, and there is an increase in number of patients taking blood thinners, we are seeing more and more patients on blood thinners prior to endoscopic procedures. Gastrointestinal bleeding or thromboembolism can occur in this category of patients in the periendoscopic period. To better manage these patients, endoscopists should have a clear concept about the various blood thinners in the market. Patients’ risk of thromboembolism off anticoagulation, and the risk of bleeding from endoscopic procedures should be assessed prior to endoscopy. The endoscopic procedure should be done when it is safe to do it. PMID:27668068

  9. Blood thinners and gastrointestinal endoscopy

    PubMed Central

    Ahmed, Monjur

    2016-01-01

    As the number of diagnostic and therapeutic gastrointestinal endoscopies is increasing, and there is an increase in number of patients taking blood thinners, we are seeing more and more patients on blood thinners prior to endoscopic procedures. Gastrointestinal bleeding or thromboembolism can occur in this category of patients in the periendoscopic period. To better manage these patients, endoscopists should have a clear concept about the various blood thinners in the market. Patients’ risk of thromboembolism off anticoagulation, and the risk of bleeding from endoscopic procedures should be assessed prior to endoscopy. The endoscopic procedure should be done when it is safe to do it.

  10. Blood thinners and gastrointestinal endoscopy.

    PubMed

    Ahmed, Monjur

    2016-09-16

    As the number of diagnostic and therapeutic gastrointestinal endoscopies is increasing, and there is an increase in number of patients taking blood thinners, we are seeing more and more patients on blood thinners prior to endoscopic procedures. Gastrointestinal bleeding or thromboembolism can occur in this category of patients in the periendoscopic period. To better manage these patients, endoscopists should have a clear concept about the various blood thinners in the market. Patients' risk of thromboembolism off anticoagulation, and the risk of bleeding from endoscopic procedures should be assessed prior to endoscopy. The endoscopic procedure should be done when it is safe to do it. PMID:27668068

  11. 45 CFR 88.2 - Complaint handling and investigating.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (OCR) of the Department of Health and Human Services is designated to receive complaints based on the Federal health care provider conscience protection statutes. OCR will coordinate the handling...

  12. 45 CFR 88.2 - Complaint handling and investigating.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... (OCR) of the Department of Health and Human Services is designated to receive complaints based on the Federal health care provider conscience protection statutes. OCR will coordinate the handling...

  13. 45 CFR 88.2 - Complaint handling and investigating.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (OCR) of the Department of Health and Human Services is designated to receive complaints based on the Federal health care provider conscience protection statutes. OCR will coordinate the handling...

  14. 45 CFR 88.2 - Complaint handling and investigating.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... (OCR) of the Department of Health and Human Services is designated to receive complaints based on the Federal health care provider conscience protection statutes. OCR will coordinate the handling...

  15. 29 CFR 1603.107 - Dismissals of complaints.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE GOVERNMENT EMPLOYEE RIGHTS ACT OF 1991 Administrative Process § 1603.107 Dismissals of...

  16. 29 CFR 1603.104 - Service of the complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE GOVERNMENT EMPLOYEE RIGHTS ACT OF 1991 Administrative Process § 1603.104 Service of the...

  17. 29 CFR 1603.105 - Withdrawal of a complaint.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF THE GOVERNMENT EMPLOYEE RIGHTS ACT OF 1991 Administrative Process § 1603.105 Withdrawal of a...

  18. 18 CFR 343.4 - Procedure on complaints.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., DEPARTMENT OF ENERGY REGULATIONS UNDER THE INTERSTATE COMMERCE ACT PROCEDURAL RULES APPLICABLE TO OIL PIPELINE PROCEEDINGS § 343.4 Procedure on complaints. (a) Responses. The carrier must file an answer to...

  19. 18 CFR 343.4 - Procedure on complaints.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., DEPARTMENT OF ENERGY REGULATIONS UNDER THE INTERSTATE COMMERCE ACT PROCEDURAL RULES APPLICABLE TO OIL PIPELINE PROCEEDINGS § 343.4 Procedure on complaints. (a) Responses. The carrier must file an answer to...

  20. 18 CFR 343.4 - Procedure on complaints.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., DEPARTMENT OF ENERGY REGULATIONS UNDER THE INTERSTATE COMMERCE ACT PROCEDURAL RULES APPLICABLE TO OIL PIPELINE PROCEEDINGS § 343.4 Procedure on complaints. (a) Responses. The carrier must file an answer to...