Science.gov

Sample records for reproductive technology centers

  1. Assisted Reproductive Technology in Iran: The First National Report on Centers, 2011

    PubMed Central

    Abedini, Mehrandokht; Ghaheri, Azadeh; Omani Samani, Reza

    2016-01-01

    Background: Due to the worldwide increase in infertility, it is both necessary and important to have assisted reproductive technology (ART) registries. In Iran, donation and surrogacy programs are approved by decrees from religious scholars. ART has been used since 1984 in Iran and the first Iranian infant conceived by gamete intra-fallopian transfer (GIFT) was born in 1989. This report, however, is the first national report on Iranian ART centers. Materials and Methods: This cross-sectional study, conducted under the supervision of the Iranian Ministry of Health, presented a summary of the numbers and percentages of centers that provided infertility services in Iran, as well as the status of ART in Iran during 2011. Results: A total of 52 centers reported treatment cycles and performed approximately 29000 intrauterine insemination (IUI), in addition to 35000 in vitro fertilization (IVF) and intra-cytoplasmic sperm injection (ICSI) cycles. Conclusion: Iran has considerable potential to provide IVF services for both Iranians as well as other nationalities throughout the region. This proves the need for a national center that will implement a registry system. PMID:27695610

  2. Society for Assisted Reproductive Technology

    MedlinePlus

    The Society for Assisted Reproductive Technology PATIENTS Patient Information What Is SART? Risks of IVF Third Party Reproduction A ... Read Article View All News ©1996 - 2016 SART, Society for Assisted Reproductive Technology . All Rights Reserved. ASRM/ ...

  3. Feminism and reproductive technologies.

    PubMed

    Callahan, Joan C

    1994-01-01

    ... Rowland is a social scientist and a radical feminist, and she has undertaken the task of making readers think twice about reproductive technologies. If a reader isn't thinking twice, it will not do to blame it on Rowland and the shortcomings of her book. She has a good deal to say that is extremely important and that needs to be considered by anyone who is interested in the moral issues, in general, and the issues for women and children, in particular, that are raised by the new and emerging reproductive technologies. Her book should be widely read. And it should generate the worries it is written to generate.

  4. Preparing for Assisted Reproductive Technology

    MedlinePlus

    ... CDC Cancel Submit Search The CDC Assisted Reproductive Technology (ART) Note: Javascript is disabled or is not ... visit this page: About CDC.gov . Assisted Reproductive Technology (ART) What Is ART Patient Resources Preparing for ...

  5. Assisted Reproductive Technology (ART)

    MedlinePlus

    ... American Society for Reproductive Medicine. (2012). Third-party reproduction (sperm, egg, and embryo donation and surrogacy): A ... from https://www.asrm.org/BOOKLET_Third-party_Reproduction [top] American Society for Reproductive Medicine. (2015). Assisted ...

  6. Mississippi Technology Transfer Center

    NASA Technical Reports Server (NTRS)

    1987-01-01

    The Mississippi Technology Transfer Center at the John C. Stennis Space Center in Hancock County, Miss., was officially dedicated in 1987. The center is home to several state agencies as well as the Center For Higher Learning.

  7. National Technology Transfer Center

    NASA Technical Reports Server (NTRS)

    Rivers, Lee W.

    1992-01-01

    Viewgraphs on the National Technology Transfer Center (NTTC) are provided. The NTTC mission is to serve as a hub for the nationwide technology-transfer network to expedite the movement of federally developed technology into the stream of commerce. A description of the Center is provided.

  8. Difficult Decisions: Reproductive Technologies.

    ERIC Educational Resources Information Center

    Parakh, Jal S.; Slesnick, Irwin L.

    1988-01-01

    Presents the arguments for and against artificial insemination and in-vitro fertilization. Cites various legal, moral, and ethical questions which can be used to promote discussion. Some people feel that the natural bond between parent and child could be weakened as a result of this new technology. (RT)

  9. Science and Technology Centers.

    ERIC Educational Resources Information Center

    Danilov, Victor J.

    Science and technology centers, which are relative newcomers to the museum field, differ from traditional museums in a number of respects. They are concerned with furthering public understanding and appreciation of the physical and biological sciences, engineering, technology, and health and seek to accomplish this goal by making museums both…

  10. [Assisted reproductive technologies and ethics].

    PubMed

    Belaisch-Allart, Joëlle

    2014-01-01

    Since the first birth after in vitro fertilization more than 5 million of IVF babies are born in the world. Assisted reproductive technologies captivate the public, they allow maternity without ovary (oocyte donation), without uterus (surrogate mother), paternity without spermatozoids (sperm donation), parentality without limits of age, parentality after death and homoparentality. These technologies arise a lot of ethics questions, the problem is that the answers are not the same all-round the world, laws are based on morals, beliefs, faiths, and convictions. Theses variations arise themselves questions on the value of these non-universal answers.

  11. "Infotonics Technology Center"

    SciTech Connect

    Fritzemeier, L.; Boysel, M. B.; Smith, D. R.

    2004-09-30

    During this grant period July 15, 2002 thru September 30, 2004, the Infotonics Technology Center developed the critical infrastructure and technical expertise necessary to accelerate the development of sensors, alternative lighting and power sources, and other specific subtopics of interest to Department of Energy. Infotonics fosters collaboration among industry, universities and government and operates as a national center of excellence to drive photonics and microsystems development and commercialization. A main goal of the Center is to establish a unique, world-class research and development facility. A state-of-the-art microsystems prototype and pilot fabrication facility was established to enable rapid commercialization of new products of particular interest to DOE. The Center has three primary areas of photonics and microsystems competency: device research and engineering, packaging and assembly, and prototype and pilot-scale fabrication. Center activities focused on next generation optical communication networks, advanced imaging and information sensors and systems, micro-fluidic systems, assembly and packaging technologies, and biochemical sensors. With targeted research programs guided by the wealth of expertise of Infotonics business and scientific staff, the fabrication and packaging facility supports and accelerates innovative technology development of special interest to DOE in support of its mission and strategic defense, energy, and science goals.

  12. [Assisted reproductive technologies in urology].

    PubMed

    Loran, O B; Segal, A S; Pushkar', D Iu; Zdanovskiĭ, V M; Tagobetskiĭ, A S; Iudovskiĭ, S O; Epifanova, E A

    2001-01-01

    Since 1996 the authors have examined and treated 42 infertile married couples (the husbands had azoospermia). To obtain spermatozoa directly from the testes or epididymis and subsequent ICSI, 42 patients underwent 53 interventions: TESE (n = 38), PESA (n = 10), MESA (n = 5). Spermatozoa were obtained from 32(76.1%) of 42 patients, fertilization occurred in 21(50%) cases, 10(23.8%) wives got pregnant. Assisted reproductive technologies expand potentialities of correcting severe forms of male infertility including azoospermia. The armory of the operative procedures in male infertility was replenished with MESA, TESE, PESA.

  13. Center for Healthcare Technologies

    SciTech Connect

    Carrano, A.V.

    1994-03-01

    In the U.S., we now spend about 13% of the gross domestic product (CDP) on healthcare. This figure represents nearly $3000 per year per man, woman, and child. Moreover, this expenditure is projected to grow to about 20% of the GDP by the year 2000. Medical research and development accounts for only about 3% of national healthcare spending, and technology development represents only a small fraction of that 3%. New technologies that are far more cost-effective than previous ones - such as minimally invasive surgical procedures, advanced automated diagnostics, and better information systems - could save the nation billions of dollars per year to say nothing of the potential reductions in pain and suffering. A center is described that will coordinate ongoing Laboratory research aimed at developing more cost-effective tools for use by the healthcare community. The new Center for Healthcare Technologies will have many long-term benefits for the region and the nation.

  14. Epigenetics and assisted reproductive technologies.

    PubMed

    Pinborg, Anja; Loft, Anne; Romundstad, Liv B; Wennerholm, Ulla-Britt; Söderström-Anttila, Viveca; Bergh, Christina; Aittomäki, Kristiina

    2016-01-01

    Epigenetic modification controls gene activity without changes in the DNA sequence. The genome undergoes several phases of epigenetic programming during gametogenesis and early embryo development, coinciding with assisted reproductive technologies (ART) treatments. Imprinting disorders have been associated with ART techniques, but disentangling the influence of the ART procedures per se from the effect of the reproductive disease of the parents is a challenge. Epidemiological human studies have shown altered birthweight profiles in ART compared with spontaneously conceived singletons. Conception with cryopreserved/thawed embryos results in a higher risk of large-for-gestational-age babies, which may be due to epigenetic modification. Further animal studies have shown altered gene expression profiles in offspring conceived by ART related to altered glucose metabolism. It is controversial whether human adolescents conceived by ART have altered lipid and glucose profiles and thereby a higher long-term risk of cardiovascular disease and diabetes. This commentary describes the basic concepts of epigenetics and gives a short overview of the existing literature on the association between imprinting disorders, epigenetic modification and ART.

  15. Control Center Technology Conference Proceedings

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Conference papers and presentations are compiled and cover evolving architectures and technologies applicable to flight control centers. Advances by NASA Centers and the aerospace industry are presented.

  16. Solar Technology Center

    SciTech Connect

    Boehm, Bob

    2011-04-27

    The Department of Energy, Golden Field Office, awarded a grant to the UNLV Research Foundation (UNLVRF) on August 1, 2005 to develop a solar and renewable energy information center. The Solar Technology Center (STC) is to be developed in two phases, with Phase I consisting of all activities necessary to determine feasibility of the project, including design and engineering, identification of land access issues and permitting necessary to determine project viability without permanently disturbing the project site, and completion of a National Environmental Policy Act (NEPA) Environmental Assessment. Phase II is the installation of infrastructure and related structures, which leads to commencement of operations of the STC. The STC is located in the Boulder City designated 3,000-acre Eldorado Valley Energy Zone, approximately 15 miles southwest of downtown Boulder City and fronting on Eldorado Valley Drive. The 33-acre vacant parcel has been leased to the Nevada Test Site Development Corporation (NTSDC) by Boulder City to accommodate a planned facility that will be synergistic with present and planned energy projects in the Zone. The parcel will be developed by the UNLVRF. The NTSDC is the economic development arm of the UNLVRF. UNLVRF will be the entity responsible for overseeing the lease and the development project to assure compliance with the lease stipulations established by Boulder City. The STC will be operated and maintained by University of Nevada, Las Vegas (UNLV) and its Center for Energy Research (UNLV-CER). Land parcels in the Eldorado Valley Energy Zone near the 33-acre lease are committed to the construction and operation of an electrical grid connected solar energy production facility. Other projects supporting renewable and solar technologies have been developed within the energy zone, with several more developments in the horizon.

  17. Technology Development Center at NICT

    NASA Technical Reports Server (NTRS)

    Takefuji, Kazuhiro; Ujihara, Hideki

    2013-01-01

    The National Institute of Information and Communications Technology (NICT) is developing and testing VLBI technologies and conducts observations with this new equipment. This report gives an overview of the Technology Development Center (TDC) at NICT and summarizes recent activities.

  18. Clean Air Technology Center Products

    EPA Pesticide Factsheets

    The Clean Air Technology Center provides resources for emerging and existing air pollution prevention and control technologies and provides public access to data and information on their use, effectiveness and cost.

  19. Reproductive Technologies and Genomic Selection in Cattle

    PubMed Central

    Humblot, Patrice; Le Bourhis, Daniel; Fritz, Sebastien; Colleau, Jean Jacques; Gonzalez, Cyril; Guyader Joly, Catherine; Malafosse, Alain; Heyman, Yvan; Amigues, Yves; Tissier, Michel; Ponsart, Claire

    2010-01-01

    The recent development of genomic selection induces dramatic changes in the way genetic selection schemes are to be conducted. This review describes the new context and corresponding needs for genomic based selection schemes and how reproductive technologies can be used to meet those needs. Information brought by reproductive physiology will provide new markers and new improved phenotypes that will increase the efficiency of selection schemes for reproductive traits. In this context, the value of the reproductive techniques including assisted embryo based reproductive technologies (Multiple Ovaluation Embryo Transfer and Ovum pick up associated to in vitro Fertilization) is also revisited. The interest of embryo typing is discussed. The recent results obtained with this emerging technology which are compatible with the use of the last generation of chips for genotype analysis may lead to very promising applications for the breeding industry. The combined use of several embryo based reproductive technologies will probably be more important in the near future to satisfy the needs of genomic selection for increasing the number of candidates and to preserve at the same time genetic variability. PMID:20981298

  20. Center for Space Microelectronics Technology

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The 1990 technical report of the Jet Propulsion Laboratory Center for Space Microelectronics Technology summarizes the technical accomplishments, publications, presentations, and patents of the center during 1990. The report lists 130 publications, 226 presentations, and 87 new technology reports and patents.

  1. Center for space microelectronics technology

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The 1992 Technical Report of the Jet Propulsion Laboratory Center for Space Microelectronics Technology summarizes the technical accomplishments, publications, presentations, and patents of the center during the past year. The report lists 187 publications, 253 presentations, and 111 new technology reports and patents in the areas of solid-state devices, photonics, advanced computing, and custom microcircuits.

  2. Center for Space Microelectronics Technology

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The 1991 Technical Report of the Jet Propulsion Laboratory Center for Space Microelectronics Technology summarizes the technical accomplishments, publications, presentations, and patents of the Center during the past year. The report lists 193 publications, 211 presentations, and 125 new technology reports and patents.

  3. Reproductive technology: in the Netherlands, tolerance and debate.

    PubMed

    De Wachter, Maurice A M; De Wert, Guido MWR

    1987-06-01

    Two ethicists from the Netherlands' Institute for Bioethics file a report on their country in one of six Hastings Center Report articles on the status of reproductive technologies around the world. The situation in the Netherlands reflects the tolerant attitudes of the Dutch toward what are regarded as private matters. Artificial insemination, in vitro fertilization, and surrogate motherhood are available, and research on embryos is in the planning stages. Facilities offering reproductive services are regulated by the Minister of Health, with advice from the independent Health Council on Artificial Reproduction, the National Council for Public Health, and various insurance companies and professional medical organizations. Public policy debates center around such issues as the value of parenthood; involvement of third parties; secrecy about a child's genetic origins; privacy for semen, ovum, and embryo donors; access to services; and insurance coverage of treatment.

  4. Bioethics for clinicians: 26. Assisted reproductive technologies

    PubMed Central

    Shanner, Laura; Nisker, Jeffrey

    2001-01-01

    ASSISTED REPRODUCTIVE TECHNOLOGIES (ARTs) can be very helpful for certain patients, but ethical concerns have been raised about the inherent nature of specific techniques and the contexts in which many techniques are used. Physicians play important roles in supporting those who wish to become parents and in educating patients about impediments to fertilization and ways to promote conception. We discuss various ethical issues surrounding ARTs, including family relationships, informed choice, gender issues, embryo status and the commercialization of reproduction, as well as legal and policy issues. We examine the empirical evidence of the effectiveness of ARTs and suggest ways to approach ARTs in practice. PMID:11402801

  5. Contemporary genetic technologies and female reproduction

    PubMed Central

    Fauser, B.C.J.M.; Diedrich, K.; Bouchard, P.; Domínguez, F.; Matzuk, M.; Franks, S.; Hamamah, S.; Simón, C.; Devroey, P.; Ezcurra, D.; Howles, C.M.

    2011-01-01

    BACKGROUND The Fifth Evian Annual Reproduction (EVAR) Workshop Meeting discussed knowledge regarding contemporary genetics in female reproduction. METHODS Specialist reproductive medicine clinicians and geneticists delivered presentations based on published literature and current research. The content of this report is based on the expert presentations and subsequent group discussions that took place during this Workshop. RESULTS Numerous ovarian genes with a role in infertility have been identified. Future challenges for genetic screening of patients, such as those with polycystic ovary syndrome, primary ovarian insufficiency or endometriosis, include the identification of high-throughput strategies and how to apply these findings to infertile patients. The identification of high-quality embryos in IVF using objective technologies remains a high priority in order to facilitate single-embryo transfer. Gene expression profiling of cumulus cells surrounding the oocyte, and proteomic and metabolomic approaches in embryo culture media may significantly improve non-invasive embryo quality assessment. CONCLUSIONS The way forward in advancing the knowledge of genes involved in reproduction was considered to be through genome-wide association studies involving large numbers of patients. Establishing international collaboration is required to enable the application of such technologies in sufficient numbers of patients. PMID:21896560

  6. Morgantown Energy Technology Center, technology summary

    SciTech Connect

    Not Available

    1994-06-01

    This document has been prepared by the DOE Environmental Management (EM) Office of Technology Development (OTD) to highlight its research, development, demonstration, testing, and evaluation activities funded through the Morgantown Energy Technology Center (METC). Technologies and processes described have the potential to enhance DOE`s cleanup and waste management efforts, as well as improve US industry`s competitiveness in global environmental markets. METC`s R&D programs are focused on commercialization of technologies that will be carried out in the private sector. META has solicited two PRDAs for EM. The first, in the area of groundwater and soil technologies, resulted in twenty-one contact awards to private sector and university technology developers. The second PRDA solicited novel decontamination and decommissioning technologies and resulted in eighteen contract awards. In addition to the PRDAs, METC solicited the first EM ROA in 1993. The ROA solicited research in a broad range of EM-related topics including in situ remediation, characterization, sensors, and monitoring technologies, efficient separation technologies, mixed waste treatment technologies, and robotics. This document describes these technology development activities.

  7. HEMISPHERIC CENTER FOR ENVIRONMENTAL TECHNOLOGY

    SciTech Connect

    M.A. Ebadian

    1999-10-31

    The Deactivation and Decommissioning (D&D) Technology Assessment Program (TAP) was developed to provide detailed, comparable data for environmental technologies and to disseminate this data to D&D professionals in a manner that will facilitate the review and selection of technologies to perform decontamination and decommissioning. The objectives for this project include the following: Determine technology needs through review of the Site Technology Coordination Group (STCG) information and other applicable websites and needs databases; Perform a detailed review of industries that perform similar activities as those required in D&D operations to identify additional technologies; Define the technology assessment program for characterization and waste management problem sets; Define the data management program for characterization, dismantlement, and waste management problem sets; Evaluate baseline and innovative technologies under standard test conditions at Florida International University's Hemispheric Center for Environmental Technology (FIU-HCET) and other locations and collect data in the areas of performance, cost, health and safety, operations and maintenance, and primary and secondary waste generation; Continue to locate, verify, and incorporate technology performance data from other sources into the multimedia information system; and Develop the conceptual design for a dismantlement technology decision analysis tool for dismantlement technologies.

  8. Center for Advanced Computational Technology

    NASA Technical Reports Server (NTRS)

    Noor, Ahmed K.

    2000-01-01

    The Center for Advanced Computational Technology (ACT) was established to serve as a focal point for diverse research activities pertaining to application of advanced computational technology to future aerospace systems. These activities include the use of numerical simulations, artificial intelligence methods, multimedia and synthetic environments, and computational intelligence, in the modeling, analysis, sensitivity studies, optimization, design and operation of future aerospace systems. The Center is located at NASA Langley and is an integral part of the School of Engineering and Applied Science of the University of Virginia. The Center has four specific objectives: 1) conduct innovative research on applications of advanced computational technology to aerospace systems; 2) act as pathfinder by demonstrating to the research community what can be done (high-potential, high-risk research); 3) help in identifying future directions of research in support of the aeronautical and space missions of the twenty-first century; and 4) help in the rapid transfer of research results to industry and in broadening awareness among researchers and engineers of the state-of-the-art in applications of advanced computational technology to the analysis, design prototyping and operations of aerospace and other high-performance engineering systems. In addition to research, Center activities include helping in the planning and coordination of the activities of a multi-center team of NASA and JPL researchers who are developing an intelligent synthesis environment for future aerospace systems; organizing workshops and national symposia; as well as writing state-of-the-art monographs and NASA special publications on timely topics.

  9. Process Engineering Technology Center Initiative

    NASA Technical Reports Server (NTRS)

    Centeno, Martha A.

    2001-01-01

    NASA's Kennedy Space Center (KSC) is developing as a world-class Spaceport Technology Center (STC). From a process engineering (PE) perspective, the facilities used for flight hardware processing at KSC are NASA's premier factories. The products of these factories are safe, successful shuttle and expendable vehicle launches carrying state-of-the-art payloads. PE is devoted to process design, process management, and process improvement, rather than product design. PE also emphasizes the relationships of workers with systems and processes. Thus, it is difficult to speak of having a laboratory for PE at KSC because the entire facility is practically a laboratory when observed from a macro level perspective. However, it becomes necessary, at times, to show and display how KSC has benefited from PE and how KSC has contributed to the development of PE; hence, it has been proposed that a Process Engineering Technology Center (PETC) be developed to offer a place with a centralized focus on PE projects, and a place where KSC's PE capabilities can be showcased, and a venue where new Process Engineering technologies can be investigated and tested. Graphics for showcasing PE capabilities have been designed, and two initial test beds for PE technology research have been identified. Specifically, one test bed will look into the use of wearable computers with head mounted displays to deliver work instructions; the other test bed will look into developing simulation models that can be assembled into one to create a hierarchical model.

  10. Society for Assisted Reproductive Technology and assisted reproductive technology in the United States: a 2016 update.

    PubMed

    Toner, James P; Coddington, Charles C; Doody, Kevin; Van Voorhis, Brad; Seifer, David B; Ball, G David; Luke, Barbara; Wantman, Ethan

    2016-09-01

    The Society for Assisted Reproductive Technology (SART) was established within a few years of assisted reproductive technology (ART) in the United States, and has not only reported on the evolution of infertility care, but also guided it toward improved success and safety. Moving beyond its initial role as a registry, SART has expanded its role to include quality assurance, data validation, practice and advertising guidelines, research, patient education and advocacy, and membership support. The success of ART in this country has greatly benefited from SART's role, as highlighted by a series of graphs. SART continues to set the standard and lead the way.

  11. Center for Computational Structures Technology

    NASA Technical Reports Server (NTRS)

    Noor, Ahmed K.; Perry, Ferman W.

    1995-01-01

    The Center for Computational Structures Technology (CST) is intended to serve as a focal point for the diverse CST research activities. The CST activities include the use of numerical simulation and artificial intelligence methods in modeling, analysis, sensitivity studies, and optimization of flight-vehicle structures. The Center is located at NASA Langley and is an integral part of the School of Engineering and Applied Science of the University of Virginia. The key elements of the Center are: (1) conducting innovative research on advanced topics of CST; (2) acting as pathfinder by demonstrating to the research community what can be done (high-potential, high-risk research); (3) strong collaboration with NASA scientists and researchers from universities and other government laboratories; and (4) rapid dissemination of CST to industry, through integration of industrial personnel into the ongoing research efforts.

  12. NCI Technology Transfer Center | TTC

    Cancer.gov

    The National Cancer Institute’s Technology Transfer Center (TTC) facilitates partnerships between the NIH research laboratories and external partners. With specialized teams, TTC guides the interactions of our partners from the point of discovery to patenting, from invention development to licensing. We play a key role in helping to accelerate development of cutting-edge research by connecting our partners to NIH’s world-class researchers, facilities, and knowledge.

  13. Cancer in Women after Assisted Reproductive Technology

    PubMed Central

    Luke, Barbara; Brown, Morton B.; Spector, Logan G.; Missmer, Stacey A.; Leach, Richard E.; Williams, Melanie; Koch, Lori; Smith, Yolanda; Stern, Judy E.; Ball, G. David; Schymura, Maria J.

    2015-01-01

    Objective To evaluate the risk of cancer after assisted reproductive technology (ART) therapy. Design Longitudinal cohort of New York, Texas, and Illinois residents between 2004-09, treated with ART, and whose cycles were reported to the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System (SART CORS). Setting Not applicable Patients Cycles of 113,226 women, including 53,859 women without prior ART treatment, were linked to their respective Cancer Registries. Standardized incidence ratios (SIR) and their 95% confidence intervals were calculated, comparing the observed to expected cancer cases based on age-specific cancer rates in the general population of each State. Among the cohort of women without prior ART therapy, hazard ratios (HR) and 95% confidence intervals were calculated for treatment parameters and reproductive history factors. Intervention None Main Outcome Measures Diagnosis of cancer, as reported to the State Cancer Registry Results Mean follow-up was 4.87 years; among women without prior ART, 450 women developed 460 cancers. Women treated with ART had significantly lower risks for all cancers (for all women: SIR 0.78, 0.73-0.83; and women without prior ART: SIR 0.75, 0.68-0.82), breast cancer, and all female genital cancers; nonsignificant lower risks for endocrine and uterine cancer; and nonsignificant higher risks for melanoma and ovarian cancer. Among women without prior ART, there were no significant increased HRs by parity, number of cycles, cumulative FSH dosage, or cycle outcome. Conclusions These results suggest no greater risks for developing cancer after nearly 5 years of follow-up compared to the general population, and to other women treated with ART. Capsule These results suggest no greater short-term risks for developing cancer compared to the general population, and to other women treated with ART. PMID:26271227

  14. Process Engineering Technology Center Initiative

    NASA Technical Reports Server (NTRS)

    Centeno, Martha A.

    2002-01-01

    NASA's Kennedy Space Center (KSC) is developing as a world-class Spaceport Technology Center (STC). From a process engineering (PE) perspective, the facilities used for flight hardware processing at KSC are NASA's premier factories. The products of these factories are safe, successful shuttle and expendable vehicle launches carrying state-of-the-art payloads. PE is devoted to process design, process management, and process improvement, rather than product design. PE also emphasizes the relationships of workers with systems and processes. Thus, it is difficult to speak of having a laboratory for PE at K.S.C. because the entire facility is practically a laboratory when observed from a macro level perspective. However, it becomes necessary, at times, to show and display how K.S.C. has benefited from PE and how K.S.C. has contributed to the development of PE; hence, it has been proposed that a Process Engineering Technology Center (PETC) be developed to offer a place with a centralized focus on PE projects, and a place where K.S.C.'s PE capabilities can be showcased, and a venue where new Process Engineering technologies can be investigated and tested. Graphics for showcasing PE capabilities have been designed, and two initial test beds for PE technology research have been identified. Specifically, one test bed will look into the use of wearable computers with head mounted displays to deliver work instructions; the other test bed will look into developing simulation models that can be assembled into one to create a hierarchical model.

  15. Center for Advanced Separation Technology

    SciTech Connect

    Honaker, Rick

    2013-09-30

    The U.S. is the largest producer of mining products in the world. In 2011, U.S. mining operations contributed a total of $232 billion to the nation’s GDP plus $138 billion in labor income. Of this the coal mining industry contributed a total of $97.5 billion to GDP plus $53 billion in labor income. Despite these contributions, the industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginia Tech and West Virginia University, CAST is now a five-university consortium – Virginia Tech, West Virginia University, University of Kentucky, University of Utah and Montana Tech, - that is supported through U.S. DOE Cooperative Agreement No. DE-FE0000699, Center for Advanced Separation Technology. Much of the research to be conducted with Cooperative Agreement funds will be longer term, high-risk, basic research and will be carried out in two broad areas: Advanced Pre-Combustion Clean Coal Technologies and Gas-Gas Separations. Distribution of funds is handled via competitive solicitation of research proposals through Site Coordinators at the five member universities. These were reviewed and the selected proposals were forwarded these to the DOE/NETL Project Officer for final review and approval. The successful projects are listed below by category, along with abstracts from their final reports.

  16. Sperm proteome and reproductive technologies in mammals.

    PubMed

    Li, Chun-Jin; Wang, Dong; Zhou, Xu

    2016-10-01

    Sperm is highly differentiated cell that can be easily obtained and purified. Mature sperm is considered to be transcriptionally and translationally silent and incapable of protein synthesis. Recently, a large number of proteins have been identified in sperm from different species by using the proteomic approaches. Clinically, sperm proteins can be used as markers for male infertility due to different protein profiles identified in sperm from fertile and infertile male animals. Recent evidences have shown that the conditions of sperm preservation in vitro can also change the sperm protein profiles. This paper reviews the recent scientific publications available to address sperm proteome and their relationship with sperm cryopreservation, capacitation, fertilization, and separation of X and Y sperm. Future directions in the application of sperm proteomics to develop or optimize reproductive technologies in mammals are also discussed.

  17. Reproductive Technology in the Context of Reproductive Teleology

    ERIC Educational Resources Information Center

    Cooper, Neil J.; Hampton, Simon Jonathan

    2007-01-01

    This article argues that in the ordinary course of events, most parents routinely practice "reproductive teleology" in that they attempt to manipulate the physical and psychological characteristics of children, and they do so as part of the process of good parenting. Furthermore, such attempts are socially approved of and encouraged. With these…

  18. [Parenting stress in women who concieved using assisted reproductive technology].

    PubMed

    Yu, Y C; Kuo, B J

    2001-06-01

    Infertile women suffer chronic stress, which may negatively impact their parenting relationships if they later succeed in bearing children. The purpose of this study was to explore the parenting stress of mothers attending assisted an reproductive program and to compare it with the parenting stress of mothers with natural pregnancies. A purposive sampling method was used to recruit 54 mothers attending an In Vitro Fertilization/Embryo Transfer and Tubal Embryo Transfer program at an infertility center in central Taiwan. Three instruments were used to collect data: the Demographic Data Form, Parenting Stress Index-Short Form and Family Adaptation Partnership Growth Affective Relation Index. The data were analyzed by descriptive and inferential statistical methods. (1) The results indicated that the highest average score in parenting stress for mothers receiving reproductive technology was for "parental distress". These results revealed that the main source of parenting stress was their parental role. (2) Family function varied significantly with parenting stress. (3) Parenting stress was significantly greater in mothers with natural pregnancy than in mothers attending the assisted reproductive program. Recommendations for clinical application and future research are also made. The implications of the study may be used to assist infertile women in coping with parenting roles. Furthermore, a qualitative study is suggested to understand the factors which cause parenting stress.

  19. Assisted reproductive technologies and fertility "tourism": examples from global Dubai and the Ivy League.

    PubMed

    Inhorn, Marcia C; Shrivastav, Pankaj; Patrizio, Pasquale

    2012-01-01

    What motivates the global movements of infertile people searching for assisted reproductive technologies (ARTs)? In this article, we attempt to answer this question by exploring infertile patients' practices of so-called "fertility tourism." Based on ethnographic research carried out with nearly 300 infertile travelers in two major ART centers--one in the global hub of the United Arab Emirates and the other at a major East Coast Ivy League university--we examine a diverse set of reasons for reproductive travel. We argue that reproductive "tourism" should be reconceptualized as reproductive "exile" in that infertile couples feel barred from accessing ARTs in their home countries. Listening to reproductive travel stories is key to understanding infertile couples' transnational "quests for conception." Stories of two couples, one from Lebanon and one from Italy, demonstrate the poignancy of these quests and begin to shed light on the complex calculus of factors governing this global movement of reproductive actors.

  20. Training in reproductive endocrinology and infertility and assisted reproductive technologies: options and worldwide needs.

    PubMed

    de Ziegler, Dominique; de Ziegler, Nathalie; Sean, Sokteang; Bajouh, Osama; Meldrum, David R

    2015-07-01

    Standardized, high-quality training in reproductive endocrinology, infertility, and assisted reproductive technologies (REI-ART) faces challenges owing to the high-tech nature of ART and the important country-to-country differences in clinical practice and regulations overseeing training. Moreover, while the training capacity of the classical by-fellowship training platforms is shrinking, an increasing demand for REI-ART specialists is coming from emerging countries. To meet this expanding need for REI-ART specialists, we propose a novel by-network model linking a reference training center to satellite practical training sites. Simulation should be used more extensively to achieve competency before initiating live clinical experience, analogous to the highly effective training systems that have been used in aviation for decades. Large ART databases that exist because of obligations to report ART activity and results constitute unique yet so far untapped sources for developing by-scenario simulation training models. Online training materials incorporating these state-of-the-art information technology tools could be developed as a means of fulfilling training needs worldwide.

  1. 75 FR 51815 - National Toxicology Program (NTP); Center for the Evaluation of Risks to Human Reproduction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... (NTP); Center for the Evaluation of Risks to Human Reproduction (CERHR); Evaluation of the Health... reproduction and/or development and provide opinion on whether these substances are hazardous for...

  2. Childhood outcomes of assisted reproductive technology.

    PubMed

    Savage, Tim; Peek, John; Hofman, Paul L; Cutfield, Wayne S

    2011-09-01

    There is a large population of children conceived via assisted reproductive technology (ART), which continues to increase worldwide, without a clear understanding of associated long-term outcomes. ART children are more likely to be the result of multiple pregnancies, and thus to be born prematurely or low birthweight. There is growing evidence that ART children are phenotypically and biochemically different from naturally conceived children, but the mechanism(s) leading to these changes have not been elucidated. There is a possible increased risk of rare imprinted gene disorders in these children. However, it remains unclear whether more subtle changes in DNA methylation occur commonly, leading to differences in gene expression and phenotype in ART children. Although an increased risk of cancer among ART children has been reported, the role of ART in the development of cancer has not been demonstrated. Further research and ongoing surveillance of ART children is essential to better understand the possible effects of ART on the long-term health of this population.

  3. Center for Nanoscale Science and Technology

    National Institute of Standards and Technology Data Gateway

    NIST Center for Nanoscale Science and Technology (Program website, free access)   Currently there is no database matching your keyword search, but the NIST Center for Nanoscale Science and Technology website may be of interest. The Center for Nanoscale Science and Technology enables science and industry by providing essential measurement methods, instrumentation, and standards to support all phases of nanotechnology development, from discovery to production.

  4. Reproductive health professionals' adoption of emerging technologies for health promotion.

    PubMed

    Smith, Peggy B; Buzi, Ruth S

    2014-12-01

    The purpose of this study was to assess reproductive health professionals' familiarity with and use of various electronic technologies to support health promotion. The study also examined the relationship between demographic characteristics and attitudes and beliefs of the effectiveness of new technologies and perceived barriers for usage. A total of 165 reproductive health professionals at two conferences related to reproductive health in the United States completed the study survey. Personal and organizational factors affected the adoption of electronic technologies for health promotion. This included lack of knowledge, skills, and confidence as well as privacy concerns. The results of the study also suggested that being from an older generation was associated with having lower levels of knowledge, skills, and confidence in using new media. These findings highlight the importance of creating learning opportunities on the use of new technology for health promotion as well as addressing specific perceived barriers among reproductive health professionals in order to promote the adoption of these technologies.

  5. About the Clean Air Technology Center

    EPA Pesticide Factsheets

    The Clean Air Technology Center provides resources for emerging and existing air pollution prevention and control technologies and provides public access to data and information on their use, effectiveness and cost.

  6. Reproductive technologies and the quality of offspring in Asia: reproductive pioneering and moral pragmatism?

    PubMed

    Sleeboom-Faulkner, Margaret

    2010-02-01

    This paper highlights a number of theoretical issues relevant to this special issue of Culture, Health & Sexuality on the quality of offspring, including gender selection, ecofeminism, eugenics, reproductive agency, moral pioneering and reproductive pragmatism in China, India and Japan. First, it discusses various approaches to choice in sex selection, focusing on an instrumentalist and an ecofeminist approach. Second, it discusses issues of reproductive choice in the light of various concepts of eugenics and power, which have been used to characterise the relationship between the state, the individual and prenatal genetic testing. Third, it queries Foucault's notion of biopower in relation to reproductive agency. In reviewing the evidence, the chapter raises questions about how women and parents in Asian societies can be understood in terms of 'reproductive pragmatism', 'empowerment' and/or 'moral pioneering' when faced with the use of new reproductive technologies in modern societies.

  7. The Psychologist's Role in Family Building with Reproductive Technology.

    ERIC Educational Resources Information Center

    Mikesell, Susan G.

    About 1 in 12 couples in the United States face the "how to have" element of reproductive choices. Assistive Reproductive Technology (ART) involves manipulation of genetic material outside of the body. Infertile couples have a large range of options in the achievement of a conception and are easily overwhelmed. As new choices are offered…

  8. Responding to Industry Demands: Advanced Technology Centers.

    ERIC Educational Resources Information Center

    Smith, Elizabeth Brient

    1991-01-01

    Discusses characteristics identified by the Center for Occupational Research and Development as indicative of fully functioning advanced technology centers, including the provision of training and retraining in such areas as design, manufacturing, materials science, and electro-optics; technology transfer; demonstration sites; needs assessment;…

  9. 75 FR 76995 - National Toxicology Program (NTP); Center for the Evaluation of Risks to Human Reproduction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-10

    ... Reproduction (CERHR); NTP Workshop: Role of Environmental Chemicals in the Development of Diabetes and Obesity... established the NTP Center for the Evaluation of Risks to Human Reproduction (CERHR) in 1998 (63 FR 68782) to... (collectively referred to as ``substances'') cause adverse effects on reproduction and development and...

  10. Technology, Biopolitics, Rationalities and Choices: Recent Studies of Reproduction.

    PubMed

    Whittaker, Andrea

    2015-01-01

    New synergies across anthropology, science and technology studies (STS), legal studies and sociology, bring fresh theoretical perspectives to the study of reproduction. Recent works on reproduction trace some of the changing rationalities: from the tactics of feminist self-help health movements in 1970s and 1980s in the US, to the commercialized experience of pregnancy and the various configurations, policies and legalities addressing globalized genetic and assisted reproductive technologies. Reproductive decision-making is deeply entangled with neoliberalism, welfare reforms, racial and geographic disparities, economic stratification and cultural rationalities to produce inequalities. Studies of reproduction remain central to basic anthropological questions: what it means to be human, what constitutes life, how we live our lives, and how societies value particular lives.

  11. Current status of assisted reproductive technology in Korea, 2009.

    PubMed

    Choi, Young Min; Chun, Sang Sik; Han, Hyuck Dong; Hwang, Jung Hye; Hwang, Kyung Joo; Kang, In Soo; Kim, Dong Won; Kim, Ki Chul; Kim, Tak; Kwon, Hyuck Chan; Lee, Won Don; Lee, Jung Ho; Lee, Kyu Sup; Lee, Gyoung Hoon; Lee, Sang-Hoon; Lee, Yu Il; Min, Eung Gi; Moon, Hwa Sook; Moon, Shin Yong; Roh, Sung Il; Yoon, Tae Ki

    2013-11-01

    Great advances have been made in the field of assisted reproductive technology (ART) since the first in vitro fertilization (IVF) baby was born in Korea in the year of 1985. However, it deserve to say that the invaluable data from fertility centers may serve as a useful source to find out which factors affect successful IVF outcome and to offer applicable information to infertile patients and fertility clinics. This article intended to report the status of ART in 2009 Korean Society of Obstetrics and Gynecology surveyed. The current survey was performed to assess the status and success rate of ART performed in Korea, between January 1 and December 31, 2009. Reporting forms had been sent out to IVF centers via e-mail, and collected by e-mail as well in 2012. With International Committee Monitoring Assisted Reproductive Technologies recommendation, intracytoplasmic sperm injection (ICSI) and non-ICSI cases have been categorized and also IVF-ET cases involving frozen embryo replacement have been surveyed separately. Seventy-four centers have reported the treatment cycles initiated in the year of 2009, and had performed a total of 27,947 cycles of ART treatments. Among a total of 27,947 treatment cycles, IVF and ICSI cases added up to 22,049 (78.9%), with 45.3% IVF without ICSI and 54.7% IVF with ICSI, respectively. Among the IVF and ICSI patients, patients confirmed to have achieved clinical pregnancy was 28.8% per cycle with oocyte retrieval, and 30.9% per cycle with embryo transfer. The most common number of embryos transferred in 2009 is three embryos (40.4%), followed by 2 embryos (28.4%) and a single embryo transferred (13.6%). Among IVF and ICSI cycles that resulted in multiple live births, twin pregnancy rate was 45.3% and triple pregnancy rate was 1.1%. A total of 191 cases of oocyte donation had been performed to result in 25.0% of live birth rate. Meanwhile, a total of 5,619 cases of frozen embryo replacement had been performed with 33.7% of clinical

  12. HEMISPHERIC CENTER FOR ENVIRONMENTAL TECHNOLOGY

    SciTech Connect

    M.A. Ebadian

    1999-04-30

    The final data package has been completed for the Mississippi State University, DIAL FTP Wall Depth Removal Characterization Technology. The package has been sent to DIAL for comments. Work is progressing on completing the transfer of glove boxes and tanks from Rocky Flats to FIU-HCET for the purpose of performing size reduction technology assessments. Vendors are being identified and security measures are being put in place to meet the High Risk Property criteria required by Rocky Flats. The FIU-HCET Technology Assessment Program has been included as one of 11 verification programs across the US and Canada described in the Interstate Technology Regulatory Cooperation (ITRC) document, ''Multi-state Evaluation of Elements Important to the Verification of Remediation Technologies'', dated January 1999. FIU-HCET will also participate in a panel discussion on technology verification programs at the International Environmental Technology Expo '99.

  13. Search Technologies | NCI Technology Transfer Center | TTC

    Cancer.gov

    Our team of technology transfer specialists has specialized training in invention reporting, patenting, patent strategy, executing technology transfer agreements and marketing. TTC is comprised of professionals with diverse legal, scientific, and business/marketing expertise. Most of our staff hold doctorate-level technical and/or legal training.

  14. Available Technologies | NCI Technology Transfer Center | TTC

    Cancer.gov

    Our team of technology transfer specialists has specialized training in invention reporting, patenting, patent strategy, executing technology transfer agreements and marketing. TTC is comprised of professionals with diverse legal, scientific, and business/marketing expertise. Most of our staff hold doctorate-level technical and/or legal training.

  15. [Activities and responsibilities of workers in embryologic and andrologic laboratories in assisted reproduction centers].

    PubMed

    Záková, J; Trávník, P; Malenovská, A; Hűttelová, R

    2013-11-01

    This paper presents the current status and rules for the laboratory staff activities and their competences in the centers of assisted reproduction. The rules were processed by the members of the Association of Reproductive Embryology (ARE) committee under the current legislation. Committee members of the Czech Sterility and Assisted Reproduction Society and Czech Gynecology and Obstetric Society approved these rules as obligatory for assisted reproduction centres in Czech Republic.

  16. HEMISPHERIC CENTER FOR ENVIRONMENTAL TECHNOLOGY

    SciTech Connect

    M.A. Ebadian

    1999-05-31

    The programming and website for the advanced Technology Information System (TIS) have been completed. Over and above the LSDDP-TIS, the new system provides information on DOE's baseline technologies, technology data contained in DOE's databases, technologies assessed at FIU-HCET Technology Assessment Program (TAP), as well as links to other selected D&D sites with valuable technology information. The new name for the website is Gateway for Environmental Technology (GET). A super-vacuum type blasting system was tested for decontamination of 12-in pipe internal surfaces. The system operates on compressed air and propels grit media at high speed at wall surfaces. It is equipped with a vacuum system for collecting grit, dust, and debris. This technology was selected for further development. The electret ion chamber (EIC) system for measurement of alpha contamination on surfaces has been calibrated and is ready for demonstration and deployment. FIU-HCET is working with representatives from Fernald, Oak Ridge, Rocky Flats, and Savannah River to procure a demonstration and deployment site. Final arrangements are ongoing for the mock-up design for the glove box and tank size reduction technology assessments, including designing of support bases for tanks, a piping support system, and a mobilization plan for glove boxes and tanks from storage site to the PermaCon.

  17. Research and technology at Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    1989-01-01

    As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, Kennedy Space Center is placing increasing emphasis on the Center's research and technology program. In addition to strengthening those areas of engineering and operations technology that contribute to safer, more efficient, and more economical execution of current mission, the technical tools are developed needed to execute Center's mission relative to future programs. The Engineering Development Directorate encompasses most of the laboratories and other Center resources that are key elements of research and technology program implementation and is responsible for implementation of the majority of the projects in this Kennedy Space Center 1989 Annual Report.

  18. HEMISPHERIC CENTER FOR ENVIRONMENTAL TECHNOLOGY

    SciTech Connect

    M.A. Ebadian

    1999-01-31

    FIU-HCET participated in an ICT meeting at Mound during the second week of December and presented a brief videotape of the testing of the Robotic Climber technology. During this meeting, FIU-HCET proposed the TechXtract technology for possible testing at Mound and agreed to develop a five-page proposal for review by team members. FIU-HCET provided assistance to Bartlett Inc. and General Lasertronics Corporation in developing a proposal for a Program Opportunity Notice (PON). The proposal was submitted by these companies on January 5, 1999. The search for new equipment dismantlement technologies is continuing. The following vendors have responded to requests for demonstration: LUMONICS, Laser Solutions technology; CRYO-BEAM, Cryogenic cutting technology; Waterjet Technology Association, Waterjet Cutting technology; and DIAJET, Waterjet Cutting technology. Based on the tasks done in FY98, FIU-HCET is working closely with Numatec Hanford Corporation (NHC) and Pacific Northwest National Laboratory (PNNL) to revise the plan and scope of work of the pipeline plugging project in FY99, which involves activities of lab-scale flow loop experiments and a large-scale demonstration test bed.

  19. Center for Instructional Technology: A Strategic Imperative

    ERIC Educational Resources Information Center

    Volzer, Debra; Weaver, Mark

    2004-01-01

    Ohio Dominican University, a small traditional Catholic Liberal Arts University steeped in the Dominican tradition, is in the midst of a technological metamorphosis. At the forefront of the change is the Center for Instructional Technology. Charged with supporting the development of technology enhanced, hybrid, and totally online curriculum, the…

  20. Technologies and the Secondary School Writing Center

    ERIC Educational Resources Information Center

    Inman, James A.

    2006-01-01

    Although the use of computers in secondary school writing centers has been pioneering in some instances, it has at other times been problematic. It is important to be clear at the outset that using particular technologies for the sake of those particular technologies is a bad idea. While technologies are always present in our lives, they are…

  1. Advanced technologies for Mission Control Centers

    NASA Technical Reports Server (NTRS)

    Dalton, John T.; Hughes, Peter M.

    1991-01-01

    Advance technologies for Mission Control Centers are presented in the form of the viewgraphs. The following subject areas are covered: technology needs; current technology efforts at GSFC (human-machine interface development, object oriented software development, expert systems, knowledge-based software engineering environments, and high performance VLSI telemetry systems); and test beds.

  2. Haystack Observatory Technology Development Center

    NASA Technical Reports Server (NTRS)

    Beaudoin, Chris; Corey, Brian; Niell, Arthur; Cappallo, Roger; Whitney, Alan

    2013-01-01

    Technology development at MIT Haystack Observatory were focused on four areas in 2012: VGOS developments at GGAO; Digital backend developments and workshop; RFI compatibility at VLBI stations; Mark 6 VLBI data system development.

  3. HEMISPHERIC CENTER FOR ENVIRONMENTAL TECHNOLOGY

    SciTech Connect

    M.A. Ebadian

    1999-07-31

    FIU-HCET personnel visited the Special Technologies Laboratory (STL) for discussions with the Principal Investigator (PI) of Laser Induced Fluorescence Imaging (LIFI) and for training in LIFI. Mr. Peter Gibbons, Tanks Retrieval Technology Integration Manager, visited FIU-HCET on July 20, 1999. Mr. Gibbons inspected the pipeline unplugging experimental facility at the HCET testing field. The detailed test bed construction, testing plan, and plugging material specifications were discussed.

  4. The Goddard Earth Sciences and Technology Center (GEST Center)

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The following is a technical report of the progress made under Cooperative Agreement NCC5494, the Goddard Earth Sciences and Technology Center (GEST). The period covered by this report is October 1, 2001 through December 31, 2001. GEST is a consortium of scientists and engineers, led by the University of Maryland, Baltimore County (UMBC), to conduct scientific research in Earth and information sciences and related technologies in collaboration with the NASA Goddard Space Flight Center (GSFC). GEST was established through a cooperative agreement signed May 11, 2000, following a competitive procurement process initiated by GSFC.

  5. NASA(Field Center Based) Technology Commercialization Centers

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Under the direction of the IC(sup 2) Institute, the Johnson Technology Commercialization Center has met or exceeded all planned milestones and metrics during the first two and a half years of the NTCC program. The Center has established itself as an agent for technology transfer and economic development in- the Clear Lake community, and is positioned to continue as a stand-alone operation. This report presents data on the experimental JTCC program, including all objective measures tracked over its duration. While the metrics are all positive, the data indicates a shortage of NASA technologies with strong commercial potential, barriers to the identification and transfer of technologies which may have potential, and small financial return to NASA via royalty-bearing licenses. The Center has not yet reached the goal of self-sufficiency based on rental income, and remains dependent on NASA funding. The most important issues raised by the report are the need for broader and deeper community participation in the Center, technology sourcing beyond JSC, and the form of future funding which will be appropriate.

  6. Spectacular reproduction: Ron's Angels and mechanical reproduction in the age of ART (assisted reproductive technology).

    PubMed

    Hafstein, Valdimar Tr

    2007-03-01

    Ron Harris captured the popular imagination in October 1999 with a website where he auctioned off the ova of fashion models to the highest bidder. This article treats the controversy surrounding Harris' site within a dual frame of critical theory's approach to reproduction and a folkloristic approach to discourse. The website fuses traditional narrative motifs and structures with the logic of advertising, seventies television, family-values rhetoric, and the fertility industry. I argue that the great attraction of ronsangels.com is that it put into relief the intervention of mechanical reproduction in human fertility together with the state of genetics at the turn of the 21st century. The result is not only a disconcerting aestheticization and commodification of biological reproduction, but also the biological reproduction of a particular aesthetic and moral code--a generation of reality by model.

  7. HEMISPHERIC CENTER FOR ENVIRONMENTAL TECHNOLOGY

    SciTech Connect

    M.A. Ebadian

    1999-03-30

    A vendor was selected for the diamond wire technology demonstration scheduled for this summer at Princeton Plasma Physics Laboratory (PPPL). A team consisting of personnel from FIU-HCET, PPPL, and AEA Technology reviewed the submitted bids. FIU-HCET will contract this vendor. At the SRS Ninth ICT teleconference, the ICT team discussed the status of the following demonstrations: LRAD; x-ray, K-edge; Strippable Coatings; Thermal Spray Vitrification; Cutting/Shearing/Dismantlement/Size Reduction; and Electrets. The LRAD demo is complete, and the x-ray/K-edge, Strippable Coatings, and Electrets demos are ongoing. The Asbestos and Thermal Spray Vitrification demos require more laboratory testing. The Cutting/Shearing/Dismantlement/Size Reduction demo is undergoing procurement. Five FIU-HCET staff members took the 1S0 14000 environmental auditor training course February 22-26, 1999, given by ASC. The test plan for the Facility Dismantlement Technology Assessment is finished and ready for internal review.

  8. Savannah River Technology Center monthly report

    SciTech Connect

    Not Available

    1992-10-01

    This document contains many small reports from personnel at the technology center under the umbrella topics of reactors, tritium, separations, environment, waste management, and general engineering. Progress and accomplishments are given.

  9. Rock Port Celebrates New Technology Center.

    ERIC Educational Resources Information Center

    Grones, Freda

    1997-01-01

    Discusses the advantages dome architecture gave to a new school technology center in Rock Port, Missouri. Advantages cover energy cost savings, lighting, storage space, aesthetics, accessibility, and convenience. (GR)

  10. Savannah River Technology Center, monthly report

    SciTech Connect

    Not Available

    1994-04-01

    This is the monthly report to detail the research currently being conducted at the Savannah River Technology Center. The areas of research are in Tritium, Seperation processes, Environmental Engineering, and Waste Management.

  11. The Learning Technology Center at Vanderbilt University.

    ERIC Educational Resources Information Center

    Bransford, John

    1994-01-01

    Describes the Vanderbilt University (Tennessee) Learning Technology Center, including profile of the center's personnel; description of representative projects, such as the Jasper-Woodbury Problem Solving Series, a multimedia literacy program for grades K-3, and the Adult Literacy Program; and a list of 14 representative publications by center…

  12. HEMISPHERIC CENTER FOR ENVIRONMENTAL TECHNOLOGY

    SciTech Connect

    M.A.Ebadian

    1999-02-28

    Search for decontamination technologies to be assessed at FIU-HCET continues. Bartlett Nuclear Inc. returned to FIU-HCET on February 15-19, 1999, to complete the demonstration of coating removal from concrete ceiling and aggressive contamination removal on uncoated concrete wall using their Robotic Climber. The design of test beds for large-scale technology demonstration of blockage locating and pipe unplugging has undergone major revision. The lab-scale test loop is also under modification. A new sampling system using isokinetic principles and consisting of thermistors, flow controller, and Wheatstone bridge will be installed on the flow loop. FIU-HCET International Coordinator attended the VII Steering Committee meeting in Lima, Peru, on February 11-12, 1999, and successfully introduced the Interactive Communication Website. Additional agenda items on the Website were proposed by the Steering Committee for upcoming committee meetings and working groups.

  13. HEMISPHERIC CENTER FOR ENVIRONMENTAL TECHNOLOGY

    SciTech Connect

    M.A. Ebadian

    1999-06-30

    To enhance the measurement capability of EICs to alpha spectrometry, measurements at FIU-HCET were performed on different energy alpha sources, and response factors of ST electrets in 960-mL chamber were determined. Earlier, EIC was considered as only a charge-integrating device without spectrometric capability. This is a potentially significant development accomplished by FIU-HCET. It could appreciably lower the current cost of spectral characterization. FIU-HCET has been invited to participate in the Operating Engineers' National Hazmat program's assessment of the Mini Mitter, commercially known as the VitalSense{trademark} Telemetric Monitoring System. This evaluation is scheduled for early July 1999. Additional health and safety technology evaluations, in which FIU-HCET will also participate, are also scheduled for later in the summer. The Technology Information System (TIS), MISD, and DASD are now complete and accessible through the Internet website http://www.DandD.org/tis.

  14. Technologies for Learner-Centered Feedback

    ERIC Educational Resources Information Center

    Costello, Jane; Crane, Daph

    2013-01-01

    As the number, type, and use of technologies to support learning increases, so do the opportunities for using these technologies for feedback. Learner-centered feedback is a core to the teaching-learning process. It is related to assessment in describing how learners perform in their learning, their gain in knowledge, skills, and attitudes.…

  15. Join TTC! | NCI Technology Transfer Center | TTC

    Cancer.gov

    The NCI Technology Transfer Center (TTC) offers a unique opportunity for training through the NCI TTC Fellowship program. TTC also has a unit dedicated to marketing these research opportunities and their underlying technologies to potential collaborators and licensees. | [google6f4cd5334ac394ab.html

  16. Educational Technology Center Third Year Report.

    ERIC Educational Resources Information Center

    Educational Technology Center, Cambridge, MA.

    The Educational Technology Center (ETC) was established by the National Institute of Education in October, 1983, in order to find ways of using the computer and other information technologies to teach science, mathematics, and computing more effectively. This report describes the ETC, presents its framework for research, and summarizes work on 11…

  17. Educational Technology Center First Year Report.

    ERIC Educational Resources Information Center

    Educational Technology Center, Cambridge, MA.

    The Educational Technology Center (ETC) was established by the National Institute of Education in October, 1983, in order to find ways of using the computer and other information technologies to teach science, mathematics, and computing more effectively. This report describes the ETC, presents its framework for research, and summarizes work on 14…

  18. Educational Technology Center Second Year Report.

    ERIC Educational Resources Information Center

    Educational Technology Center, Cambridge, MA.

    The Educational Technology Center (ETC) was established by the National Institute of Education in October, 1983, in order to find ways of using the computer and other information technologies to teach science, mathematics, and computing more effectively. This report describes the ETC, presents its framework for research, and summarizes work on 12…

  19. HEMISPHERIC CENTER FOR ENVIRONMENTAL TECHNOLOGY

    SciTech Connect

    M.A. Ebadian

    1999-09-30

    The Princeton Plasma Physics Laboratory (PPPL) demonstration of the diamond wire cutting technology on the surrogate of the Tokamak Fusion Test Reactor (TFTR), Figure 1, was performed from August 23-September 3, 1999. The plated diamond wire, Figure 2, was successful in cutting through all components of the TFTR surrogate including stainless steel, inconel and graphite. The demonstration tested three different void fill materials (mortar with sand, Rheocell-15, and foam) and three cooling systems (water, air, and liquid nitrogen). The optimum combination was determined to be the use of the low-density concrete void fill, Rheocell-15 with an average density of 52 lbs/ft{sup 3}, using a water coolant. However, the liquid nitrogen performed better than expected with only minor problems and was considered to be a successful demonstration of the Bluegrass Concrete Cutting, Inc. proprietary liquid-nitrogen coolant system. Data from the demonstration is being calculated and a summary of the technology demonstration will be included in the October monthly report. An ITSR will be written comparing the diamond wire saw to the plasma arc (baseline) technology. The MTR Chemical Protective Suit, a proprietary new suit from Kimberly Clark, was evaluated from 8/9/99 to 8/12/99 at Beaver, WV. This particular suit was tested on subjects performing three different tasks: climbing through a horizontal confined space, vertical confined space (pit), and loading and unloading material using a wheel barrow. Multiple test subjects performed each task for 20 minutes each. Performance of the innovative suit was compared to two commonly used types of protective clothing. Vital statistics, including body temperature and heart rate, were continuously monitored and recorded by an authorized physician. A summary of the demonstration will be included in the October monthly report. Along with the MTR Chemical Protective Suit, the VitalSense{trademark} Telemetric Monitoring System from Mini Mitter

  20. HEMISPHERIC CENTER FOR ENVIRONMENTAL TECHNOLOGY

    SciTech Connect

    M.A. Ebadian

    2000-01-31

    The Online Measurement of Decontamination project team received a commitment for a demonstration in May from the Sacramento (California) Municipal Utility District (SMUD) Rancho Seco site. Since this site is a member of the DOE Commercial Utilities Consortium, the demonstration will fulfill the DOE and commercial technology demonstration requirements. Discussion on deployment of the Integrated Vertical and Overhead Decontamination (IVOD) System at Rancho Seco was conducted; date for deployment tentatively scheduled for early spring. Based upon fictional requirements from SRS for a shiny monitor in a high-level waste tank, FIU-HCET developed and delivered a draft slurry monitor design and draft test plan. Experiments measuring slurry settling time for SRS slurry simulant at 10 wt% have been completed on FIU-HCET'S flow loop with SRS dip. The completed design package of the test mockup for evaluating Non-Intrusive Location of Buried Items Technologies was sent to Fluor Fernald and the Operating Engineers National Hazmat Program for review. Comments are due at the end of January. Preliminary experiments to determine size distribution of aerosols generated during metal cutting were performed. A 1/4-inch-thick iron plate was cut using a plasma arc torch, and the size distribution of airborne particles was measured using a multistage impactor. Per request of DOE-Ohio, FIU-HCET participated in a weeklong value engineering study for the characterization, decontamination, and dismantlement of their critical path facility.

  1. Human reproductive technologies and the law: a select committee report.

    PubMed

    2005-05-01

    The House of Commons Science & Technology Committee has reviewed the Human Fertilisation and Embryology Act. It considered a) the balance between legislation, regulation and reproductive freedom; b) the role of Parliament in human reproductive technologies; and c) the foundation, adequacy and appropriateness of the ethical framework for legislation. It also considered the Act itself and the workings of the Human Fertilisation and Embryology Authority. Its report is written from a very liberal perspective, but is a very thorough overview of current issues and debate in the field. There follow, slightly abridged, the conclusions and recommendations of the 200-page report.

  2. A Catholic ethical approach to human reproductive technology.

    PubMed

    Ford, Norman M

    2008-01-01

    This article presents the Catholic Christian tradition and teaching on the moral respect due to human life from conception, supported by natural law moral philosophical reasoning. This approach contrasts with the ethical views of secular philosophers on human embryo research for therapeutic purposes. The challenges for Catholic healthcare institutions is to find ethical ways of using suitable pluripotent stem cells for therapies without creating or destroying human embryos. Catholic teaching on infertility treatment and reproductive technology are presented with emphasis given to the ethical need for children to be conceived and born of the marriage union compared with alterative ethical approaches for the use of infertility treatment and reproductive technology.

  3. What can progress in reproductive technology mean for women?

    PubMed

    Purdy, L M

    1996-10-01

    This article critically evaluates the central claims of the various feminist responses to new reproductive arrangements and technologies. Proponents of a "progressivism" object to naive technological optimism and raise questions about the control of such technology. Others, such as the FINRRAGE group, raise concerns about the potentially damaging consequences of the new technologies for women. While a central concern is whether these technologies reinforce harmful biologically determinist stereotypes of women, it may be that these critiques function with a devastating gender blindness that puts women at risk in other, heretofore unnoticed, ways.

  4. Assisted Reproductive Technology and Risk for Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Zachor, Ditza A.; Itzchak, E. Ben

    2011-01-01

    Epidemiologic studies on maternal and pregnancy risk factors for autism spectrum disorder (ASD), including use of assisted reproductive technology (ART), found conflicting results. This study included the following aims: to assess frequencies of ART in a large ASD group; to examine confounding birth and familial risk factors in the ASD with ART…

  5. Emergent Legal Definitions of Parentage in Assisted Reproductive Technology

    ERIC Educational Resources Information Center

    Robinson, Cherylon; Miller, Michael V.

    2004-01-01

    State statutes and court cases involving Assisted Reproductive Technology (ART) are examined to determine legal definitions of father and mother. While traditional definitions are not disturbed overall by statutes and cases involving use of artificial insemination by donor among married couples, complications and disputes between parties involved…

  6. Developing Multipurpose Reproductive Health Technologies: An Integrated Strategy

    PubMed Central

    Harrison, P. F.; Hemmerling, A.; Romano, J.; Whaley, K. J.; Young Holt, B.

    2013-01-01

    Women worldwide confront two frequently concurrent reproductive health challenges: the need for contraception and for protection from sexually transmitted infections, importantly HIV/AIDS. While conception and infection share the same anatomical site and mode of transmission, there are no reproductive health technologies to date that simultaneously address that reality. Relevant available technologies are either contraceptive or anti-infective, are limited in number, and require different modes of administration and management. These “single-indication” technologies do not therefore fully respond to what is a substantial reproductive health need intimately linked to pivotal events in many women's lives. This paper reviews an integrated attempt to develop multipurpose prevention technologies—“MPTs”—products explicitly designed to simultaneously address the need for both contraception and protection from sexually transmitted infections. It describes an innovative and iterative MPT product development strategy with the following components: identifying different needs for such technologies and global variations in reproductive health priorities, defining “Target Product Profiles” as the framework for a research and development “roadmap,” collating an integrated MPT pipeline and characterizing significant pipeline gaps, exploring anticipated regulatory requirements, prioritizing candidates for problem-solving and resource investments, and implementing an ancillary advocacy agenda to support this breadth of effort. PMID:23533733

  7. The future of mothering: reproductive technology and feminist theory.

    PubMed

    Donchin, A

    1986-01-01

    An exploration of (I) alternative perspectives toward recent innovations in reproductive technology: support for new techniques for the sake of the kind of feminist future they facilitate; unqualified opposition despite therapeutic benefit to individual women; or qualified opposition depending upon specific threats to women's interests and (II) relationships between these positions and values bound up with mothering practices.

  8. Just another reproductive technology? The ethics of human reproductive cloning as an experimental medical procedure.

    PubMed

    Elsner, D

    2006-10-01

    Human reproductive cloning (HRC) has not yet resulted in any live births. There has been widespread condemnation of the practice in both the scientific world and the public sphere, and many countries explicitly outlaw the practice. Concerns about the procedure range from uncertainties about its physical safety to questions about the psychological well-being of clones. Yet, key aspects such as the philosophical implications of harm to future entities and a comparison with established reproductive technologies such as in vitro fertilisation (IVF) are often overlooked in discussions about HRC. Furthermore, there are people who are willing to use the technology. Several scientists have been outspoken in their intent to pursue HRC. The importance of concerns about the physical safety of children created by HRC and comparisons with concerns about the safety of IVF are discussed. A model to be used to determine when it is acceptable to use HRC and other new assisted reproductive technologies, balancing reproductive freedom and safety concerns, is proposed. Justifications underpinning potential applications of HRC are discussed, and it is determined that these are highly analogous to rationalisations used to justify IVF treatment. It is concluded that people wishing to conceive using HRC should have a prima facie negative right to do so.

  9. Cryopreservation in assisted reproductive technology: new trends.

    PubMed

    Nawroth, Frank; Rahimi, Gohar; Isachenko, Eugenia; Isachenko, Vladimir; Liebermann, Maike; Tucker, Michael J; Liebermann, Juergen

    2005-11-01

    During the last few years, cryopreservation has become a relevant addition to therapeutic concepts in reproductive medicine. New data and publications have made it difficult to maintain an overview of all of the new developments and their results. The focus of interest more recently, especially with the cryopreservation of human oocytes and human ovarian tissue, has been vitrification as an interesting alternative to slow freezing methods. Even though studies investigating the slow freezing of human mature oocytes have resulted in very different survival rates, it could be an option for donor oocyte programs, in the case of threatened ovarian loss or when there is an objection to embryo freezing. An optimal freezing protocol and later use of thawed human ovarian tissue is still a point of discussion. There are encouraging results regarding different kinds of autotransplantation, and recently the first birth after orthotopic autotransplantation of cryopreserved/thawed human ovarian tissue was described in the literature. Independent of any objections to cryopreservation in general, vitrification is a potential and effective alternative to conventional slow cryopreservation, especially for oocytes and embryos. Vitrification might be also be an option for human ovarian tissue; however this is only in its infancy and requires much additional investigation. Our article discusses new trends and results of actual studies regarding these issues.

  10. Graduate Automotive Technology Education (GATE) Center

    SciTech Connect

    Jeffrey Hodgson; David Irick

    2005-09-30

    The Graduate Automotive Technology Education (GATE) Center at the University of Tennessee, Knoxville has completed its sixth year of operation. During this period the Center has involved thirteen GATE Fellows and ten GATE Research Assistants in preparing them to contribute to advanced automotive technologies in the center's focus area: hybrid drive trains and control systems. Eighteen GATE students have graduated, and three have completed their course work requirements. Nine faculty members from three departments in the College of Engineering have been involved in the GATE Center. In addition to the impact that the Center has had on the students and faculty involved, the presence of the center has led to the acquisition of resources that probably would not have been obtained if the GATE Center had not existed. Significant industry interaction such as internships, equipment donations, and support for GATE students has been realized. The value of the total resources brought to the university (including related research contracts) exceeds $4,000,000. Problem areas are discussed in the hope that future activities may benefit from the operation of the current program.

  11. Conservation of the European mink (Mustela lutreola): focus on reproduction and reproductive technologies.

    PubMed

    Amstislavsky, S; Lindeberg, H; Aalto, J; Kennedy, M W

    2008-08-01

    The European mink (Mustela lutreola) is a small mammal, which belongs to the Mustelidae family (Carnivora). Earlier, the range of distribution of this species encompassed much of the European continent. During the 20th century, the numbers of European mink declined and the range of its distribution became reduced to three fragmented populations; today this species faces extinction. The urgent necessity for effective conservation efforts to protect the European mink is accepted by the governmental organizations as well as scientific communities of most European countries. In this paper, the reasons for the disappearance of European mink are reviewed and results of past conservation efforts based on captive breeding and reintroduction programmes are critically evaluated in the broad context of modern concepts of conservation genetics and reproductive biology. The data recently obtained on the reproduction and pre-implantation development of European mink and the prospects of incorporation of modern reproductive technologies into the conservation programme of this species are discussed.

  12. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Christopher E. Hull

    2006-05-15

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  13. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Christopher E. Hull

    2005-11-04

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  14. Crosscutting Technology Development at the Center for Advanced Separation Technologies

    SciTech Connect

    Christopher E. Hull

    2006-09-30

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  15. Johnson Space Center Research and Technology Report

    NASA Technical Reports Server (NTRS)

    Pido, Kelle; Davis, Henry L. (Technical Monitor)

    1999-01-01

    As the principle center for NASA's Human Exploration and Development of Space (HEDS) Enterprise, the Johnson Space Center (JSC) leads NASA's development of human spacecraft, human support systems, and human spacecraft operations. To implement this mission, JSC has focused on developing the infrastructure and partnerships that enable the technology development for future NASA programs. In our efforts to develop key technologies, we have found that collaborative relationships with private industry and academia strengthen our capabilities, infuse innovative ideas, and provide alternative applications for our development projects. The American public has entrusted NASA with the responsibility for space--technology development, and JSC is committed to the transfer of the technologies that we develop to the private sector for further development and application. It is our belief that commercialization of NASA technologies benefits both American industry and NASA through technology innovation and continued partnering. To this end, we present the 1998-1999 JSC Research and Technology Report. As your guide to the current JSC technologies, this report showcases the projects in work at JSC that may be of interest to U.S. industry, academia, and other government agencies (federal, state, and local). For each project, potential alternative uses and commercial applications are described.

  16. Reproductive technologies relevant to the genome resource bank in Carnivora.

    PubMed

    Amstislavsky, S; Lindeberg, H; Luvoni, Gc

    2012-02-01

    Carnivora is one of the most species-rich order of Mammalia. Some species, e.g. domestic cats, dogs and ferrets, are among the most popular pets; others, such as minks and farmed foxes, have economic value for the fur breeding industry. Still others, such as tigers, bears and other top predators, have great impact on the health of natural ecosystems. Most if not all Carnivora species have great cultural and aesthetic importance for man. There are enormous differences between mammalian species in reproductive physiology, and it is not surprising that reproductive technologies can be used with high efficiency with some animal groups, e.g. most farm animals and laboratory rodents, but are very laborious when used with Carnivora species, which often possess unique reproductive traits. The efficiency of assisted reproductive technology (ART) applied to semi-domestic, non-domestic and especially to endangered species of Carnivora remains extremely low in most cases, and often the first positive result reported is the only instance when ART has been successful with that species. Although there are approximately 270 species in the Carnivora order, to the best of our knowledge, successful published attempts to apply ART have been reported for only four families: Mustelidae, Felidae, Canidae and Ursidae. The main achievements in ART, embryo technology in particular, for these families of Carnivora, together with challenges and problems, are reviewed in the relevant sections.

  17. "Baby oh baby"--advances in assisted reproductive technology.

    PubMed

    Solursh, D S; Schorer, J W; Solursh, L P

    1997-01-01

    It is estimated that one couple in six in the United States has to deal with issues of infertility. It is assumed that worldwide rates are comparable. In 35% of cases, the infertility is caused by female reproductive problems, in 35% by male reproductive problems, in 15% by multiple factors and in 15% the cause is unknown. Medical and scientific advances in Assisted Reproductive Technology (ART) have created 12 different pregnancy producing options for infertile couples. An ART infant could have as many as five parents (i.e. a donor father, a donor mother, a surrogate or gestational mother, and the couple actually rearing the child). These technical, medical, and moral complexities have resulted in a nightmare of accompanying legal complexities: anonymous donors versus those with identification disclosed, parental rights, grandparental rights, the rights of siblings and of the extended families; sperm, ovum and embryo "ownership", custody, visitation and inheritance rights and multiple other issues challenge a system of laws that evolves far slower than the technological realities to which it applies. This presentation will describe Assisted Reproductive Technology advances and the legal implications inherent in them. Case histories will be discussed.

  18. License Agreements | NCI Technology Transfer Center | TTC

    Cancer.gov

    Since the government cannot engage in the development, manufacture, and sale of products, the NCI Technology Transfer Center (TTC) makes its discoveries (and discoveries from nine other NIH Institutes) available to organizations that can assist in the further development and commercialization of these basic science discoveries, to convert them into public health benefits. | [google6f4cd5334ac394ab.html

  19. Goddard Earth Sciences and Technology Center (GEST)

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This document summarizes the activities of the Goddard Earth Sciences and Technology Center (GEST), a consortium of scientists and engineers led by the University of Maryland, Baltimore County (UMBC), during the contract reporting period. Topics covered include: new programs, eligibility and selection criteria, Goddard Coastal Research Graduate Fellowship Program and staffing changes.

  20. About TTC | NCI Technology Transfer Center | TTC

    Cancer.gov

    The National Cancer Institute’s Technology Transfer Center (TTC) facilitates partnerships between the NIH research laboratories and external partners, and helping to accelerate development of cutting-edge research by connecting our partners to NIH’s world-class facilities, resources, and discoveries. Contact us to learn more. | [google6f4cd5334ac394ab.html

  1. Research and technology, 1991. Langley Research Center

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The mission of the NASA Langley Research Center is to increase the knowledge and capability of the United States in a full range of aeronautics disciplines and in selected space disciplines. This mission will be accomplished by performing innovative research relevant to national needs and Agency goals, transferring technology to users in a timely manner, and providing development support to other United States Government agencies, industry, and other NASA centers. Highlights are given of the major accomplishments and applications that have been made during the past year. The highlights illustrate both the broad range of the research and technology (R&T) activities at NASA Langley Research Center and the contributions of this work toward maintaining United States leadership in aeronautics and space research.

  2. Research and technology, 1989: Langley Research Center

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The mission of the NASA Langley Research Center is to increase the knowledge and capability of the United States in a full range of aeronautics disciplines and in selected space disciplines. This mission will be accomplished by performing innovative research relevant to national needs and Agency goals, transferring technology to users in a timely manner, and providing development support to other United States Government agencies, industry, and other NASA centers. Highlights of the major accomplishments and applications that were made during the past year are presented. The highlights illustrate both the broad range of the research and technology activities at NASA Langley Research Center and the contributions of this work toward maintaining United States leadership in aeronautics and space research.

  3. OMICS: Current and future perspectives in reproductive medicine and technology

    PubMed Central

    Egea, Rocío Rivera; Puchalt, Nicolás Garrido; Escrivá, Marcos Meseguer; Varghese, Alex C.

    2014-01-01

    Many couples present fertility problems at their reproductive age, and although in the last years, the efficiency of assisted reproduction techniques has increased, these are still far from being 100% effective. A key issue in this field is the proper assessment of germ cells, embryos and endometrium quality, in order to determine the actual likelihood to succeed. Currently available analysis is mainly based on morphological features of oocytes, sperm and embryos and although these strategies have improved the results, there is an urgent need of new diagnostic and therapeutic tools. The emergence of the - OMICS technologies (epigenomics, genomics, transcriptomics, proteomics and metabolomics) permitted the improvement on the knowledge in this field, by providing with a huge amount of information regarding the biological processes involved in reproductive success, thereby getting a broader view of complex biological systems with a relatively low cost and effort. PMID:25191020

  4. Marshall Space Flight Center Technology Investments Overview

    NASA Technical Reports Server (NTRS)

    Tinker, Mike

    2014-01-01

    NASA is moving forward with prioritized technology investments that will support NASA's exploration and science missions, while benefiting other Government agencies and the U.S. aerospace enterprise. center dotThe plan provides the guidance for NASA's space technology investments during the next four years, within the context of a 20-year horizon center dotThis plan will help ensure that NASA develops technologies that enable its 4 goals to: 1.Sustain and extend human activities in space, 2.Explore the structure, origin, and evolution of the solar system, and search for life past and present, 3.Expand our understanding of the Earth and the universe and have a direct and measurable impact on how we work and live, and 4.Energize domestic space enterprise and extend benefits of space for the Nation.

  5. Assisted reproductive technology (ART) in humans: facts and uncertainties.

    PubMed

    Ménézo, Y J; Veiga, A; Pouly, J L

    2000-01-15

    Since the first in vitro fertilization (IVF) in human, the number of patients using Assisted Reproductive Technologies (ART) has increased tremendously. ART technologies have increased in number and their spectrum has also widened. The first IVF babies are now more than 20 years old. All the retrospective analyses have demonstrated that the obstetrical and pediatrical impact has not really affected single births. The main problems observed occur with multiple pregnancies, including high costs for the couples and for society. The decrease in the number of embryos transferred has improved the situation and moreover does not impair the final results. IntraCytoplasmic Sperm Injection (ICSI) is a more debatable and questionable technique with a real negative genetic impact. The main problem is chromosome abnormalities more specifically related to the sex chromosomes. The question of a systematic genetic work-up on the patients entering ICSI programs is discussed. No negative impact of cryopreservation has been demonstrated even though some controversy arises from time to time. Pre-implantation Genetic Diagnosis (PGD) is now a interesting tool for patients carrying genetic defects. Blastocyst biopsy now has a future role in reproductive medicine. Gender selection through sperm sorting is also now a reality. As with the other developing bio-technologies related to reproduction, there are ethical questions. The decisions concerning these technologies do not belong solely to scientists but are rather a matter for society to decide.

  6. What would an environmentally sustainable reproductive technology industry look like?

    PubMed

    Richie, Cristina

    2015-05-01

    Through the use of assisted reproductive technologies (ARTs), multiple children are born adding to worldwide carbon emissions. Evaluating the ethics of offering reproductive services against its overall harm to the environment makes unregulated ARTs unjustified, yet the ART business can move towards sustainability as a part of the larger green bioethics movement. By integrating ecological ethos into the ART industry, climate change can be mitigated and the conversation about consumption can become a broader public discourse. Although the impact of naturally made children on the environment is undeniable, I will focus on the ART industry as an anthropogenic source of carbon emissions which lead to climate change. The ART industry is an often overlooked source of environmental degradation and decidedly different from natural reproduction as fertility centres provide a service for a fee and therefore can be subject to economic, policy and bioethical scrutiny. In this article, I will provide a brief background on the current state of human-driven climate change before suggesting two conservationist strategies that can be employed in the ART business. First, endorsing a carbon capping programme that limits the carbon emissions of ART businesses will be proposed. Second, I will recommend that policymakers eliminate funded ARTs for those who are not biologically infertile. I will conclude the article by urging policymakers and all those concerned with climate change to consider the effects of the reproductive technologies industry in light of climate change and move towards sustainability.

  7. Outcomes from infancy to adulthood after assisted reproductive technology.

    PubMed

    Shankaran, Seetha

    2014-05-01

    The outcomes of assisted reproductive technology (ART) should be not only the evaluation of successful initiation of pregnancy but also the birth of healthy infants and the evaluation of long-term outcomes of the offspring of the couple undergoing therapy. Maternal and neonatal outcomes are reported in another article in this series. This article will review the infant, childhood, adolescent, and young adult outcomes published after ART. The recent literature will be reviewed.

  8. Integrated Technology Assessment Center (ITAC) Update

    NASA Technical Reports Server (NTRS)

    Taylor, J. L.; Neely, M. A.; Curran, F. M.; Christensen, E. R.; Escher, D.; Lovell, N.; Morris, Charles (Technical Monitor)

    2002-01-01

    The Integrated Technology Assessment Center (ITAC) has developed a flexible systems analysis framework to identify long-term technology needs, quantify payoffs for technology investments, and assess the progress of ASTP-sponsored technology programs in the hypersonics area. For this, ITAC has assembled an experienced team representing a broad sector of the aerospace community and developed a systematic assessment process complete with supporting tools. Concepts for transportation systems are selected based on relevance to the ASTP and integrated concept models (ICM) of these concepts are developed. Key technologies of interest are identified and projections are made of their characteristics with respect to their impacts on key aspects of the specific concepts of interest. Both the models and technology projections are then fed into the ITAC's probabilistic systems analysis framework in ModelCenter. This framework permits rapid sensitivity analysis, single point design assessment, and a full probabilistic assessment of each concept with respect to both embedded and enhancing technologies. Probabilistic outputs are weighed against metrics of interest to ASTP using a multivariate decision making process to provide inputs for technology prioritization within the ASTP. ITAC program is currently finishing the assessment of a two-stage-to-orbit (TSTO), rocket-based combined cycle (RBCC) concept and a TSTO turbine-based combined cycle (TBCC) concept developed by the team with inputs from NASA. A baseline all rocket TSTO concept is also being developed for comparison. Boeing has recently submitted a performance model for their Flexible Aerospace System Solution for Tomorrow (FASST) concept and the ISAT program will provide inputs for a single-stage-to-orbit (SSTO) TBCC based concept in the near-term. Both of these latter concepts will be analyzed within the ITAC framework over the summer. This paper provides a status update of the ITAC program.

  9. The Hydrogen Technology Center at Wyle Laboratories

    NASA Astrophysics Data System (ADS)

    Wheelock, H.; Smith, D.; Frazier, J.

    1990-10-01

    A deactivated storable propellant test area with numerous test cells, large open concrete pads of up to 65-ft length, and two enclosed metal storage buildings, has been converted into a Hydrogen Technology Center. The conversion strategy involved extensive use of modified surplus equipment, well established testing technologies, and innovative engineering to obviate long-delivery time items. Simple, high heat flux water-to-cryogen heat exchangers are used to generate ambient temperature H2 and N gas. Hydrogen-fueled combustors were designed and fabricated to power the specialized heat exchangers required to support high-temperature hydrogen experiments. The facility has operated productively and safely since October, 1988.

  10. Center for Biophotonics Science and Technology (CBST).

    PubMed

    Chuang, Frank

    2004-01-01

    The Center for Biophotonics Science and Technology (CBST) is the only center in the country funded by the National Science Foundation and devoted to the study of light and radiant energy in biology and medicine. Our consortium of 10 world-class academic institutions and research laboratories is comprised of physical and life scientists, physicians and engineers - along with industry participants, educators and community leaders - working together to bring biophotonics to the forefront of mainstream science. The three main arms of CBST are (1) Science and Technology, (2) Education, and (3) Knowledge Transfer. The research sponsored by the center focuses on critical themes that are expected to have significant impact on current biomedical science and technology. Projects include the development of new methods in optical microscopy that work well beyond the diffraction limit; ultrafast, high-intensity X-ray lasers to resolve the structure of single biomolecules, and new devices and sensors for minimally - or noninvasive medical applications. CBST is developing a new curriculum, along with training materials, internships and research fellowships to introduce biophotonics to students and teachers at all educational levels. Finally, the knowledge transfer component of CBST is seeking to catalyze the rapid growth of biophotonics as a new technology sector by supplying intellectual capital and tools to stimulate the growth of new products and new companies. By coupling the center's biophotonics research projects with industry partners and sponsors, a unique R&D environment is created to expand the use of photons in the development of life sciences, bioengineering and health care.

  11. NASA Northeast Regional Technology Transfer Center

    NASA Technical Reports Server (NTRS)

    Dunn, James P.

    2001-01-01

    This report is a summary of the primary activities and metrics for the NASA Northeast Regional Technology Transfer Center, operated by the Center for Technology Commercialization, Inc. (CTC). This report covers the contract period January 1, 2000 - March 31, 2001. This report includes a summary of the overall CTC Metrics, a summary of the Major Outreach Events, an overview of the NASA Business Outreach Program, a summary of the Activities and Results of the Technology into the Zone program, and a Summary of the Major Activities and Initiatives performed by CTC in supporting this contract. Between January 1, 2000 and March 31, 2001, CTC has facilitated 10 license agreements, established 35 partnerships, provided assistance 517 times to companies, and performed 593 outreach activities including participation in 57 outreach events. CTC also assisted Goddard in executing a successful 'Technology into the Zone' program.' CTC is pleased to have performed this contract, and looks forward to continue providing their specialized services in support of the new 5 year RTTC Contract for the Northeast region.

  12. Research and technology, Lewis Research Center

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The NASA Lewis Research Center's research and technology accomplishments for fiscal year 1985 are summarized. The report is organized into five major sections covering aeronautics, aerospace technology, spaceflight systems, space station systems, and computational technology support. This organization of the report roughly parallels the organization of the Center into directorates. Where appropriate, subheadings are used to identify special topics under the major headings. Results of all research and technology work performed during the fiscal year are contained in Lewis-published technical reports and presentations prepared either by Lewis scientists and engineers or by contractor personnel. In addition, significant results are presented by university faculty or graduate students in technical sessions and in journals of the technical societies. For the reader who desires more information about a particular subject, the Lewis contact will provide that information or references. In 1985, five Lewis products were selected by Research and Development Magazine for IR-100 awards. All are described and identified. In addition, the Lewis Distinguished Paper for 1984 to 1985, which was selected by the Chief Scientist and a research advisory board, is included and so identified.

  13. National Wind Technology Center (Fact Sheet)

    SciTech Connect

    Not Available

    2011-12-01

    This overview fact sheet is one in a series of information fact sheets for the National Wind Technology Center (NWTC). Wind energy is one of the fastest growing electricity generation sources in the world. NREL's National Wind Technology Center (NWTC), the nation's premier wind energy technology research facility, fosters innovative wind energy technologies in land-based and offshore wind through its research and testing facilities and extends these capabilities to marine hydrokinetic water power. Research and testing conducted at the NWTC offers specialized facilities and personnel and provides technical support critical to the development of advanced wind energy systems. From the base of a system's tower to the tips of its blades, NREL researchers work side-by-side with wind industry partners to increase system reliability and reduce wind energy costs. The NWTC's centrally located research and test facilities at the foot of the Colorado Rockies experience diverse and robust wind patterns ideal for testing. The NWTC tests wind turbine components, complete wind energy systems and prototypes from 400 watts to multiple megawatts in power rating.

  14. Mission & Role | NCI Technology Transfer Center | TTC

    Cancer.gov

    The NCI TTC serves as the focal point for implementing the Federal Technology Transfer Act to utilize patents as incentive for commercial development of technologies and to establish research collaborations and licensing among academia, federal laboratories, non-profit organizations, and industry. The TTC supports technology development activities for the National Cancer Institute and nine other NIH Institutes and Centers. TTC staff negotiate co-development agreements and licenses with universities, non-profit organizations, and pharmaceutical and biotechnology companies to ensure compliance with Federal statutes, regulations and the policies of the National Institutes of Health. TTC also reviews employee invention reports and makes recommendations concerning filing of domestic and foreign patent applications. | [google6f4cd5334ac394ab.html

  15. Technology Assessments within NASA's Integrated Technology Assessment Center

    NASA Technical Reports Server (NTRS)

    Taylor, J. L.; Neely, M. A.; Curran, F. M.; Christensen, E. R.; Escher, D.; Lovell, N.

    2002-01-01

    NASA's Advanced Space Transportation Program (ASTP) founded the Integrated Technology Assessment Center (ITAC) to provide a comprehensive, systematic approach to identify long-term technology needs, to quantify payoffs for technology investments, and to assess the progress of ASTP-sponsored technology programs in the hypersonics/Earth-to-orbit area. To accomplish these goals, the ITAC has assembled an experienced team representing a broad sector of the aerospace community and developed a systematic assessment process complete with supporting tools. In the ITAC approach, concepts for transportation systems are first selected based on relevance to the ASTP. Models of these concepts are then developed and data on advanced technologies are collected. Projections of key technology characteristics with respect to the specific concepts of interest are made. Both the models and technology projections are then fed into the ITAC's probabilistic systems analysis framework. The probabilistic outputs are weighed against metrics of interest to ASTP and a multivariate decision making process is used to provide inputs for technology prioritization within the ASTP. At present, the ITAC program is working to evaluate a variety of technologies for three two-stage hypersonic vehicle concepts. Concepts include an all rocket, vertical take off-horizontal landing (VTHL) system, a horizontal takeoff-horizontal landing (HTHL) RBCC-propelled first stage/all rocket second stage system, and an HTHL turbine-based first stage/all rocket second stage system. This paper will provide a status update of the ITAC program including current results and plans.

  16. Technology Assessments within NASA's Integrated Technology Assessment Center

    NASA Technical Reports Server (NTRS)

    Taylor, J. L.; Neely, M. A.; Curran, F. M.; Christensen, E. R.; Escher, D.; Lovell, N.

    2002-01-01

    NASA's Advanced Space Transportation Program (ASTP) founded the Integrated Technology Assessment Center (ITAC) to provide a comprehensive, systematic approach to identify long-term technology needs, to quantify payoffs for technology investments, and to assess the progress of ASTP-sponsored technology programs in the hypersonics/Earth-to-orbit area. To accomplish these goals, the ITAC has assembled an experienced team representing a broad sector of the aerospace community and developed a systematic assessment process complete with supporting tools. In the ITAC approach, concepts for transportation systems are first selected based on relevance to the ASTP. Models of these concepts are then developed and data on advanced technologies are collected. Projections of key technology characteristics with respect to the specific concepts of interest are made. Both the models and technology projections are then fed into the ITAC's probabilistic systems analysis framework. The probabilistic outputs are weighed against metrics of interest to ASTP and a multivariate decision making process is used to provide inputs for technology prioritization within the ASTP. At present, the ITAC program is working to evaluate a variety of technologies for three two-stage hypersonic vehicle concepts. Concepts include an all rocket, vertical take off-horizontal landing (VTHL) system, a horizontal take-off-horizontal landing (HTHL) RBCC-propelled first stage/all rocket second stage system, and an HTHL turbine-based first stage/all rocket second stage system. This paper will provide a status update of the ITAC program including current results and plans.

  17. The Center for Environmental Technology Innovative Technology Screening Process

    SciTech Connect

    Bertrand, C.M.

    1995-02-01

    The Center for Environmental Technology`s (CET) mission is to provide a fully integrated system for accelerated evaluation, development, commercialization, and public acceptance of creative environmental solutions which match the foremost demands in today`s environmentally sensitive world. In short, CET will create a means to provide quick, effective solutions for environmental needs. To meet this mission objective, CET has created a unique and innovative approach to eliminating the usual barriers in developing and testing environmental technologies. The approach paves the way for these emerging, cutting-edge technologies by coordinating environmental restoration and waste management activities of industry, universities, and the government to: efficiently and effectively transfer technology to these users, provide market-driven, cost-effective technology programs to the public and DOE, and aid in developing innovative ideas by initiating efforts between DOE facilities and private industry. The central part to this mission is selecting and evaluating specific innovative technologies for demonstration and application at United States Department of Energy (DOE) installations. The methodology and criteria used for this selection, which is called the CET Innovative Technology Screening Process, is the subject of this paper. The selection criteria used for the screening process were modeled after other DOE technology transfer programs and were further developed by CET`s Technology Screening and Evaluation Board (TSEB). The process benefits both CET and the proposing vendors by providing objective selection procedures based on predefined criteria. The selection process ensures a rapid response to proposing vendors, all technologies will have the opportunity to enter the selection process, and all technologies are evaluated on the same scale and with identical criteria.

  18. The Savannah River Technology Center, a leader in sensor technology

    SciTech Connect

    Stewart, W.C.

    1993-12-01

    This publication highlights the capabilities and achievements of the Savannah River Technology Center in the field of sensor technology. Sensors are developed to provide solutions for environmental and chemical analysis. Most of their sensor systems are based upon fiber optics. Fiber optic probes function in three main modes: as a reflected light probe, from opaque samples; as a transreflectance probe, which sample light reflected back from samples which can pass light; and a flow cell, which monitors light transmitted through a path which passes the process stream being tested. The sensor group has developed fiber optic based temperature probes, has combined fiber optics with sol-gel technology to monitor process streams using chemical indicators, has done development work on slip stream on-line sampling of chemical process streams, has developed software to aid in the analysis of chemical solutions, and has applied this technology in a wide range of emerging areas.

  19. Research and Technology, 1987, Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Guerny, Gene (Editor); Moe, Karen (Editor); Paddack, Steven (Editor); Soffen, Gerald (Editor); Sullivan, Walter (Editor); Ballard, Jan (Editor)

    1987-01-01

    Research at Goddard Space Flight Center during 1987 is summarized. Topics addressed include space and earth sciences, technology, flight projects and mission definition studies, and institutional technology.

  20. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Hugh W. Rimmer

    2004-05-12

    This Technical Progress Report describes progress made on the seventeen subprojects awarded in the first year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices. Due to the time taken up by the solicitation/selection process, these cover the initial 6-month period of project activity only. The U.S. is the largest producer of mining products in the world. In 1999, U.S. mining operations produced $66.7 billion worth of raw materials that contributed a total of $533 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginia Tech and West Virginia University, this endeavor has been expanded into a seven-university consortium--Virginia Tech, West Virginia University, University of Kentucky, University of Utah, Montana Tech, New Mexico Tech and University of Nevada, Reno--that is supported through U.S. DOE Cooperative Agreement No. DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (1) Solid-solid separation (2) Solid-liquid separation (3) Chemical/Biological Extraction (4) Modeling and Control, and (5) Environmental Control.

  1. Center for Space Microelectronics Technology 1988-1989 technical report

    NASA Technical Reports Server (NTRS)

    Olsen, Peggy

    1990-01-01

    The 1988 to 1989 Technical Report of the JPL Center for Space Microelectronics Technology summarizes the technical accomplishments, publications, presentations, and patents of the center. Listed are 321 publications, 282 presentations, and 140 new technology reports and patents.

  2. Assessing Beaked Whale Reproduction and Stress Response Relative to Sonar Activity at the Atlantic Undersea Test and Evaluation Center

    DTIC Science & Technology

    2014-09-30

    1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Assessing Beaked Whale Reproduction and Stress Response...both groups of animals to investigate whether there is a relationship between sonar activity, stress measures, and reproductive rates, to assess... Reproduction and Stress Response Relative to Sonar Activity at the Atlantic Undersea Test and Evaluation Center (AUTEC) 5a. CONTRACT NUMBER 5b. GRANT

  3. Research and Technology 1990, Langley Research Center

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The mission of NASA-Langley is to increase the knowledge and capability of the U.S. in a full range of aeronautics disciplines and in selected space disciplines. This mission will be executed by performing innovative research relevant to national needs and agency goals, transferring technology to users in a timely manner, and providing development support to other U.S. government agencies, industry, and other NASA centers. Highlights are presented of the major accomplishments and applications that were made during the past year. The highlights illustrate both the broad range of the research and technology activitives at NASA-Langley and the contributions of this work toward maintaining U.S. leadership in aeronautics and space research.

  4. CENTER FOR ADVANCED SEPARATION TECHNOLOGY (CAST) PROGRAM

    SciTech Connect

    Yoon, Roe-Hoan; Hull, Christopher

    2014-09-30

    The U.S. is the largest producer of mining products in the world. In 2011, U.S. mining operations contributed a total of $232 billion to the nation’s GDP plus $138 billion in labor income. Of this the coal mining industry contributed a total of $97.5 billion to GDP plus $53 billion in labor income. Despite these contributions, the industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations.

  5. The future of male infertility management and assisted reproduction technology.

    PubMed

    Mortimer, D

    2000-12-01

    Intracytoplasmic sperm injection (ICSI) is undoubtedly a powerful, and sometimes the only effective, form of infertility treatment. Nonetheless, it is a non-specific treatment that, combined with increasingly heroic techniques to recover male germinal cells, has led to perceptions of men as just providers of gametes in the infertility equation. In response to this nihilist attitude, where women are investigated extensively and scant attention is paid to men, there is a re-emerging awareness of andrology--particularly in countries with limited healthcare resources. Structured management strategies, using diagnostic information to recognize causative factors amenable to simpler, even systemic, therapies with reasonable chances of pregnancy rather than resorting prematurely to assisted reproduction technology, represent rational, cost-effective approaches to infertility management. Furthermore, genetic testing (particularly cystic fibrosis gene defects and Y-chromosome microdeletions) is essential for couples to make fully informed decisions on their options. Recognition that free radical-induced damage to the sperm genome (e.g. from smoking or in-vitro sperm manipulation) underlies deleterious paternal effects on preimplantation development promotes further synergy between andrology and embryology. Although societies strike different balances between considerations of affordability and cost-effectiveness of assisted reproduction technology, ICSI represents a last resort, to be used when less-invasive, lower-cost treatments have been deemed inappropriate or have failed. Consequently, rather than assisted reproduction technology eliminating the need for andrology, the future will see increasingly tighter integration of multidisciplinary infertility care, embracing careful diagnosis and patient education before obtaining truly informed consent and embarking upon cost-effective treatment.

  6. Experience with ISO quality control in assisted reproductive technology.

    PubMed

    Alper, Michael M

    2013-12-01

    Assisted reproductive technology (ART) programs are complex organizations requiring the integration of multiple disciplines. ISO 9001:2008 is a quality management system that is readily adaptable to an ART program. The value that ISO brings to the entire organization includes control of documents, clear delineation of responsibilities of staff members, documentation of the numerous processes and procedures, improvement in tracking and reducing errors, and overall better control of systems. A quality ART program sets quality objectives and monitors their progress. ISO provides a sense of transparency within the organization and clearer understanding of how service is provided to patients. Most importantly, ISO provides the framework to allow for continual improvement.

  7. Assisted Reproductive Technology after the Birth of Louise Brown

    PubMed Central

    Kamel, Remah Moustafa

    2013-01-01

    Background Public interest in Assisted Reproductive Technology (ART) has remained high since the birth of the world’s first in vitro fertilization baby, Louise Brown, in the United Kingdom. ART allows scientists to manipulate the fertilization process in order to bypass some pathological obstacles such as blocked fallopian tubes and non-functioning ovaries in the females, and blocked vas deferens and low sperm count in the males. The purpose was to provide a historical outline and identify the researches that most contributed to ART. Methods A review of published experimental and clinical studies of assisted reproduction carried out at the University of Bristol library website (MetaLib®). A cross-search of seven different medical databases (AMED-Allied and Complementary Medicine Database, BIOSIS Previews on Web of Knowledge, Cochrane Library, Embase, and the Medline on Web of Knowledge, OvidSP and PubMed) was completed by using the key words to explore the major milestones and progress in the development and implementation of ART. Results A speedy advancement in the development of different assisted reproductive techniques makes infertility problem more treatable than it ever had been. Conclusion Although no other field in the medicine has integrated new knowledge into the daily practice more quickly than ART yet, there is a need for social research to counterbalance the dominance of biomedical one, in particular the people’s actual experiences and expectations of ART. PMID:24163793

  8. 75 FR 2545 - National Toxicology Program (NTP); Center for the Evaluation of Risks to Human Reproduction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Toxicology Program (NTP); Center for the Evaluation of Risks to Human Reproduction (CERHR); Availability of the Final Expert Panel Report on...

  9. The Morgantown Energy Technology Center`s particulate cleanup program

    SciTech Connect

    Dennis, R.A.

    1995-12-01

    The development of integrated gasification combined cycle (IGCC) and pressurized fluidized-bed combustion (PFBC) power systems has made it possible to use coal while still protecting the environment. Such power systems significantly reduce the pollutants associated with coal-fired plants built before the 1970s. This superior environmental performance and related high system efficiency is possible, in part, because particulate gas-stream cleanup is conducted at high-temperature and high-pressure process conditions. A main objective of the Particulate Cleanup Program at the Morgantown Energy Technology Center (METC) is to ensure the success of the CCT demonstration projects. METC`s Particulate Cleanup Program supports research, development, and demonstration in three areas: (1) filter-system development, (2) barrier-filter component development, and (3) ash and char characterization. The support is through contracted research, cooperative agreements, Cooperative Research And Development Agreements (CRADAs), and METC`s own in-house research. This paper describes METC`s Particulate Cleanup Program.

  10. 76 FR 39811 - International Center for Technology Assessment and the Center for Food Safety; Noxious Weed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... International Center for Technology Assessment and the Center for Food Safety (the petitioners) requested that...; ] DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service International Center for Technology Assessment and the Center for Food Safety; Noxious Weed Status of Kentucky Bluegrass Genetically...

  11. The Race Idea in Reproductive Technologies: Beyond Epistemic Scientism and Technological Mastery.

    PubMed

    Russell, Camisha

    2015-12-01

    This paper explores the limitations of epistemic scientism for understanding the role the concept of race plays in assisted reproductive technology (ART) practices. Two major limitations centre around the desire to use scientific knowledge to bring about social improvement. In the first case, undue focus is placed on debunking the scientific reality of racial categories and characteristics. The alternative to this approach is to focus instead on the way the race idea functions in ART practices. Doing so reveals how the race idea (1) helps to define the reproductive "problems" different groups of women are experiencing and to dictate when and how they should be "helped"; (2) helps to resolve tensions about who should be considered the real parents of children produced by reproductive technologies; and (3) is used to limit ART use where that use threatens to denaturalize the very sociopolitical landscape the race idea has created. In the second case, scientific knowledge regarding reproduction is thought to call for technological control over that reproduction. This leads to an overemphasis on personal responsibility and a depoliticization of racialized social inequalities.

  12. Sperm processing for advanced reproductive technologies: Where are we today?

    PubMed

    Rappa, Kari L; Rodriguez, Harold F; Hakkarainen, Gloria C; Anchan, Raymond M; Mutter, George L; Asghar, Waseem

    2016-01-01

    Assisted reproductive technologies (ARTs) utilize sperm sorting methods to select viable sperm from the semen samples. Conventional sperm sorting techniques in current use are density gradient centrifugation, direct swim-up, and conventional swim-up. These methods use multiple centrifugation steps, which have been shown to generate reactive oxygen species (ROS) that decrease DNA integrity and damage sperm. Newer technologies, such as microfluidics, electrophoresis, motile sperm organelle morphology examination (MSOME), and birefringence eliminate the centrifugation steps and can improve the selection of sperm with higher DNA integrity, normal morphology, and motility as well as improved artificial insemination outcomes. In this review, we discuss some recent research in centrifugation and non-centrifugation based techniques and their effect on sperm quality and ART outcomes.

  13. Tiger Team Assessment, Energy Technology Engineering Center

    SciTech Connect

    Not Available

    1991-04-01

    The Office Special Projects within the Office of Environment, Safety, and Health (EH) has the responsibility to conduct Tiger Team Assessments for the Secretary of Energy. This report presents the assessment of the buildings, facilities, and activities under the DOE/Rockwell Contract No. DE-AM03-76SF00700 for the Energy Technology Engineering Center (ETEC) and of other DOE-owned buildings and facilities at the Santa Susana Field Laboratory (SSFL) site in southeastern Ventura County, California, not covered under Contract No. DE-AM03-76SF00700, but constructed over the years under various other contracts between DOE and Rockwell International. ETEC is an engineering development complex operated for DOE by the Rocketdyne Division of Rockwell International Corporation. ETEC is located within SSFL on land owned by Rockwell. The balance of the SSFL complex is owned and operated by Rocketdyne, with the exception of a 42-acre parcel owned by the National Aeronautics and Space Administration (NASA). The primary mission of ETEC is to provide engineering, testing, and development of components related to liquid metals technology and to conduct applied engineering development of emerging energy technologies.

  14. The Advanced Technology Development Center (ATDC)

    NASA Technical Reports Server (NTRS)

    Clements, G. R.; Willcoxon, R. (Technical Monitor)

    2001-01-01

    NASA is building the Advanced Technology Development Center (ATDC) to provide a 'national resource' for the research, development, demonstration, testing, and qualification of Spaceport and Range Technologies. The ATDC will be located at Space Launch Complex 20 (SLC-20) at Cape Canaveral Air Force Station (CCAFS) in Florida. SLC-20 currently provides a processing and launch capability for small-scale rockets; this capability will be augmented with additional ATDC facilities to provide a comprehensive and integrated in situ environment. Examples of Spaceport Technologies that will be supported by ATDC infrastructure include densified cryogenic systems, intelligent automated umbilicals, integrated vehicle health management systems, next-generation safety systems, and advanced range systems. The ATDC can be thought of as a prototype spaceport where industry, government, and academia, in partnership, can work together to improve safety of future space initiatives. The ATDC is being deployed in five separate phases. Major ATDC facilities will include a Liquid Oxygen Area; a Liquid Hydrogen Area, a Liquid Nitrogen Area, and a multipurpose Launch Mount; 'Iron Rocket' Test Demonstrator; a Processing Facility with a Checkout and Control System; and Future Infrastructure Developments. Initial ATDC development will be completed in 2006.

  15. Development of reproductive engineering techniques at the RIKEN BioResource Center

    PubMed Central

    Ogura, Atsuo

    2016-01-01

    Reproductive engineering techniques are essential for assisted reproduction of animals and generation of genetically modified animals. They may also provide invaluable research models for understanding the mechanisms involved in the developmental and reproductive processes. At the RIKEN BioResource Center (BRC), I have sought to develop new reproductive engineering techniques, especially those related to cryopreservation, microinsemination (sperm injection), nuclear transfer, and generation of new stem cell lines and animals, hoping that they will support the present and future projects at BRC. I also want to combine our techniques with genetic and biochemical analyses to solve important biological questions. We expect that this strategy makes our research more unique and refined by providing deeper insights into the mechanisms that govern the reproductive and developmental systems in mammals. To make this strategy more effective, it is critical to work with experts in different scientific fields. I have enjoyed collaborations with about 100 world-recognized laboratories, and all our collaborations have been successful and fruitful. This review summarizes development of reproductive engineering techniques at BRC during these 15 years. PMID:27760894

  16. Technology transfer needs and experiences: The NASA Research Center perspective

    NASA Technical Reports Server (NTRS)

    Gross, Anthony R.

    1992-01-01

    Viewgraphs on technology transfer needs and experiences - the NASA Research Center perspective are provided. Topics covered include: functions of NASA, incentives and benefits, technology transfer mechanisms, economics of technology commercialization, examples, and conclusions.

  17. Technology transfer within the NASA Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Plotkin, Henry H.

    1992-01-01

    Viewgraphs on technology transfer within the NASA Goddard Space Flight Center presented to Civil Space Technology Development workshop on technology transfer and effectiveness are provided. Topics covered include: obstacles to technology transfer; technology transfer improvement program at GSFC: communication between technology developers and users; and user feedback to technologists.

  18. Scientific Data Management Center for Enabling Technologies

    SciTech Connect

    Vouk, Mladen A.

    2013-01-15

    Managing scientific data has been identified by the scientific community as one of the most important emerging needs because of the sheer volume and increasing complexity of data being collected. Effectively generating, managing, and analyzing this information requires a comprehensive, end-to-end approach to data management that encompasses all of the stages from the initial data acquisition to the final analysis of the data. Fortunately, the data management problems encountered by most scientific domains are common enough to be addressed through shared technology solutions. Based on community input, we have identified three significant requirements. First, more efficient access to storage systems is needed. In particular, parallel file system and I/O system improvements are needed to write and read large volumes of data without slowing a simulation, analysis, or visualization engine. These processes are complicated by the fact that scientific data are structured differently for specific application domains, and are stored in specialized file formats. Second, scientists require technologies to facilitate better understanding of their data, in particular the ability to effectively perform complex data analysis and searches over extremely large data sets. Specialized feature discovery and statistical analysis techniques are needed before the data can be understood or visualized. Furthermore, interactive analysis requires techniques for efficiently selecting subsets of the data. Finally, generating the data, collecting and storing the results, keeping track of data provenance, data post-processing, and analysis of results is a tedious, fragmented process. Tools for automation of this process in a robust, tractable, and recoverable fashion are required to enhance scientific exploration. The SDM center was established under the SciDAC program to address these issues. The SciDAC-1 Scientific Data Management (SDM) Center succeeded in bringing an initial set of advanced

  19. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Christopher E. Hull

    2005-01-20

    The U.S. is the largest producer of mining products in the world. In 2003, U.S. mining operations produced $57 billion worth of raw materials that contributed a total of $564 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (1) Solid-solid separation; (2) Solid-liquid separation; (3) Chemical/Biological Extraction; (4) Modeling and Control; and (5) Environmental Control.

  20. Crosscutting Technology Development at the Center for Advanced Separation Technologies

    SciTech Connect

    Christopher Hull

    2009-10-31

    The U.S. is the largest producer of mining products in the world. In 2003, U.S. mining operations produced $57 billion worth of raw materials that contributed a total of $564 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginia Tech and West Virginia University, this endeavor has been expanded into a seven-university consortium -- Virginia Tech, West Virginia University, University of Kentucky, University of Utah, Montana Tech, New Mexico Tech and University of Nevada, Reno - that is supported through U.S. DOE Cooperative Agreement No. DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (1) Solid-solid separation; (2) Solid-liquid separation; (3) Chemical/biological extraction; (4) Modeling and control; and (5) Environmental control. Distribution of funds is handled via competitive solicitation of research proposals through Site Coordinators at the seven member universities. These were first reviewed and ranked by a group of technical reviewers (selected primarily from industry). Based on these reviews, and an assessment of overall program requirements, the CAST Technical Committee made an initial selection/ranking of proposals and forwarded these to the DOE/NETL Project Officer for final review and approval. The successful projects are listed by category, along with brief abstracts of their aims and objectives.

  1. DNA methylation errors in imprinting disorders and assisted reproductive technology.

    PubMed

    Chiba, Hatsune; Hiura, Hitoshi; Okae, Hiroaki; Miyauchi, Naoko; Sato, Fumi; Sato, Akiko; Arima, Takahiro

    2013-10-01

    There have been increased incident reports of rare imprinting disorders associated with assisted reproductive technology (ART). ART is an important treatment for infertile people of reproductive age and is increasingly common. The identification of epigenetic changes at imprinted loci in ART infants has led to the suggestion that the techniques themselves may predispose embryos to acquisition of imprinting errors and disease. It is still unknown, however, at what point(s) these imprinting errors arise, or the risk factors. In this review it was hypothesized that the particular steps of the ART process may be prone to induction of imprinting methylation errors during gametogenesis, fertilization and early embryonic development. In addition, imprinting diseases and their causes are explained. Moreover, using a Japanese nationwide epidemiological study of imprinting diseases, their association with ART is determined. Epigenetic studies are required to understand the pathogenesis of this association; the ART-related risk factor(s); and the precautions that can be taken to prevent the occurrence of these syndromes. It is hoped that the constitution of children born after ART will indicate the safest and most ethical approach to use, which will be invaluable for the future development of standard ART treatment.

  2. Trends in Global Assisted Reproductive Technologies Research: a Scientometrics study

    PubMed Central

    Okhovati, Maryam; Zare, Morteza; Zare, Fatemeh; Bazrafshan, Maliheh Sadat; Bazrafshan, Azam

    2015-01-01

    Introduction This study illustrated the global contribution to assisted reproductive technologies (ARTs) research in MEDLINE database from 1998 to 2014. Methods In March 2015, the MEDLINE database was searched for research publications indexed under ‘reproductive techniques, assisted’ (including the following MeSH headings: in vitro fertilization [IVF]; intracytoplasmic sperm injections; cryopreservation; and ovulation induction), with the following expressions in the fields of title or abstract: intrauterine insemination; sperm donation; embryo/egg donation and surrogate mothers. The number of publications in MEDLINE database was recorded for each individual year, 1998–2014, and for each country. The following countries were arbitrarily selected for data retrieval: United States, United Kingdom, France, Germany, Canada, Italy, Japan (G7 countries), Brazil, Russia, India, China (BRIC countries), Egypt, Turkey, Israel and Iran. Results The absolute number of publications for each country from 1998 to 2014 ranged from 75 to 16453, with a median of 2024. The top five countries were the US (16453 publications), the UK (5427 publications), Japan (4805), China (4660) and France (3795). ART (20277), cryopreservation (11623) and IVF (11209) were the most researched areas. Conclusion Global research on ARTs were geographically distributed and highly concentrated among the world’s richest countries. Cryopreservation and IVF were the most productive research domains among ARTs. PMID:26813255

  3. Spermbots: potential impact for drug delivery and assisted reproductive technologies.

    PubMed

    Magdanz, Veronika; Schmidt, Oliver G

    2014-08-01

    Micromotors and nanomotors are an emerging research field that aims at achieving locomotion on the microscale for a variety of applications such as drug delivery, single cell manipulation, microsensors and lab-on-a-chip devices, just to point out a few. The enthusiastic development of hybrid micromotors harnessing biological power sources for physiologically compatible nano/microdevices has recently brought a lot of attention to the international research community that is looking for a solution for the actuation and locomotion on the microscale. This article describes the potential of sperm-driven micro-bio-robots in the biomedical field such as drug delivery or single cell manipulation. Herein, a specific potential of the sperm-driven micro-bio-robot is described that might have impact on the development of assisted reproductive technologies.

  4. Should HIV discordant couples have access to assisted reproductive technologies?

    PubMed Central

    Spriggs, M; Charles, T

    2003-01-01

    In this paper we identify and evaluate arguments for and against offering assisted reproductive technologies (ART), specifically IVF, to HIV discordant couples (male partner HIV positive, female partner HIV negative). The idea of offering ART to HIV discordant couples generates concerns about safety and public health and raises questions such as: what is an acceptable level of risk to offspring and should couples who want this assistance be subject to selection criteria; should they undergo scrutiny about their suitability as parents when those who are able to conceive naturally face no such scrutiny and people with other illnesses are given access to ART? We conclude that offering ART to HIV discordant couples is likely to produce more benefit than harm and violates no ethical principles. Nevertheless, a decision to deny treatment need not constitute unjustified discrimination. PMID:14662810

  5. Public policies and reproductive technology: a feminist critique.

    PubMed

    Mccormack, T

    1991-01-01

    Reproductive technology comprises abortion, contraception, amniocentesis (more than 40 genetic disorders can be diagnosed), chorionic villus sampling, genetic screening (to reduce the risk of chromosomal defects such as Down syndrome, sickle cell anemia, Tay-Sachs disease, and cystic fibrosis), in vitro fertilization, artificial insemination by spouse or donor, the development of sperm banks, storage of frozen sperm (cryopreservation), the development of artificial wombs, techniques for predetermining the sex of a fetus, and nursery environments to maintain a fetus removed from the womb in the 1st trimester. In recent years, the demand for these services has increased because of higher infertility and the drop in the number of babies available for adoption. Surrogacy is especially controversial: it has become a symbol of the dehumanization of modern life and the exploitation of women. The feminist perspective discloses how patriarchal values about the subordinate status of women, about the nature of motherhood, infertility, and the family are both implicit and explicit in prevailing thinking about reproduction. The new technology offers women who wish to remain unmarried the opportunity to have a family, and it enables lesbian women to bear children. The research literature favors a Eurocentric nuclear family without any awareness that in Canada, and in the Western world, new forms of family life have been evolving as couples marry, divorce, and remarry. There is no awareness either that in other cultures this Eurocentric nuclear model is dysfunctional. Because of the rigid notion of the 2-parent nuclear family, the 3rd parties who are involved in either surrogate relationships or artificial insemination are deprecated. The feminist literature is more critical of the nuclear family, but it has been sometimes inconsistent on the relevant issues.

  6. Biological versus chronological ovarian age: implications for assisted reproductive technology

    PubMed Central

    Alviggi, Carlo; Humaidan, Peter; Howles, Colin M; Tredway, Donald; Hillier, Stephen G

    2009-01-01

    Background Women have been able to delay childbearing since effective contraception became available in the 1960s. However, fertility decreases with increasing maternal age. A slow but steady decrease in fertility is observed in women aged between 30 and 35 years, which is followed by an accelerated decline among women aged over 35 years. A combination of delayed childbearing and reduced fecundity with increasing age has resulted in an increased number and proportion of women of greater than or equal to 35 years of age seeking assisted reproductive technology (ART) treatment. Methods Literature searches supplemented with the authors' knowledge. Results Despite major advances in medical technology, there is currently no ART treatment strategy that can fully compensate for the natural decline in fertility with increasing female age. Although chronological age is the most important predictor of ovarian response to follicle-stimulating hormone, the rate of reproductive ageing and ovarian sensitivity to gonadotrophins varies considerably among individuals. Both environmental and genetic factors contribute to depletion of the ovarian oocyte pool and reduction in oocyte quality. Thus, biological and chronological ovarian age are not always equivalent. Furthermore, biological age is more important than chronological age in predicting the outcome of ART. As older patients present increasingly for ART treatment, it will become more important to critically assess prognosis, counsel appropriately and optimize treatment strategies. Several genetic markers and biomarkers (such as anti-Müllerian hormone and the antral follicle count) are emerging that can identify women with accelerated biological ovarian ageing. Potential strategies for improving ovarian response include the use of luteinizing hormone (LH) and growth hormone (GH). When endogenous LH levels are heavily suppressed by gonadotrophin-releasing hormone analogues, LH supplementation may help to optimize treatment

  7. NTP CENTER FOR THE EVALUATION OF RISKS TO HUMAN REPRODUCTION: PHTHALATES EXPERT PANEL REPORT ON THE REPRODUCTIVE AND DEVELOPMENTAL TOXICITY OF DI-N-OCTYL PHTHALATE

    EPA Science Inventory

    Kavlock et al.; "NTP Center for the Evaluation....

    Abstract

    The phthalates are a family of environmentally important compounds with diverse uses. Reproductive toxicity has been demonstrated for some members of this family. The NTP Center for the Evaluation of Risk...

  8. Center for Space Microelectronics Technology. 1993 Technical Report

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The 1993 Technical Report of the Jet Propulsion Laboratory Center for Space Microelectronics Technology summarizes the technical accomplishments, publications, presentations, and patents of the Center during the past year. The report lists 170 publications, 193 presentations, and 84 New Technology Reports and patents. The 1993 Technical Report of the Jet Propulsion Laboratory Center for Space Microelectronics Technology summarizes the technical accomplishments, publications, presentations, and patents of the Center during the past year. The report lists 170 publications, 193 presentations, and 84 New Technology Reports and patents.

  9. Center for Global Health announces grants to support portable technologies

    Cancer.gov

    NCI's Center for Global Health announced grants that will support the development and validation of low-cost, portable technologies. These technologies have the potential to improve early detection, diagnosis, and non-invasive or minimally invasive treatm

  10. Regulatory framework in assisted reproductive technologies, relevance and main issues.

    PubMed

    Merlet, Françoise

    2009-01-01

    Assisted reproductive technologies (ART) have changed life for the past 25 years and many ethical and social issues have emerged following this new method of conception. In order to protect individuals against scientific and ethical abuses without inhibiting scientific progress, a specific legal framework is necessary. The first French law on Bioethics was voted after an extensive debate in 1994 then reviewed in 2004. This review previously scheduled every five years is currently being discussed. Legal provisions applying to ART are part of a large framework including the protection of the patients' rights and biomedical research. The key principles consist of respect for human life and ban on commercial practices of human body parts, eugenic practices and any kind of cloning. These key principles apply to ART. Donation is anonymous and free. Created in 2004, the Agence de la biomédecine is a government agency and one of the main tools of the French regulations. The missions focus on improving the quality and the safety of the management of ART. Evaluation of activities is available to all from the annual report. The agency represents the French competent authority for medical and scientific aspects of ART. Substantial differences in European legislations exist from the open-up "laissez faire" to the most restrictive one. As a consequence a large reproductive tourism has developed particularly for egg donation or surrogacy. The medical and ethical conditions of management of patients and donors represent the main critical points. In order to avoid ethical abuses, homogenization regarding the key principles is necessary in Europe. It is an opportunity to reassert that human body parts should not be a source of financial gain.

  11. Vitamin D and assisted reproduction technologies: current concepts.

    PubMed

    Vanni, Valeria S; Vigano', Paola; Somigliana, Edgardo; Papaleo, Enrico; Paffoni, Alessio; Pagliardini, Luca; Candiani, Massimo

    2014-05-31

    Accumulating evidence from animal and human studies suggests that vitamin D is involved in many functions of the human reproductive system in both genders, but no comprehensive analysis of the potential relationship between vitamin D status and Assisted Reproduction Technologies (ART) outcomes is currently available. On this basis, the purpose of this systematic review and meta-analysis was to perform an in-depth evaluation of clinical studies assessing whether vitamin D status of patients undergoing ART could be related to cycle outcome variables. This issue is of interest considering that vitamin D deficiency is easily amenable to correction and oral vitamin D supplementation is cheap and without significant side effects. Surprisingly, no studies are currently available assessing vitamin D status among male partners of couples undergoing ART, while seven studies on vitamin D status of women undergoing controlled ovarian hyperstimulation (COH) for ART were found and included in the review. Results show that vitamin D deficiency is highly prevalent among women undergoing COH, ranging from 21% to 31% across studies conducted in Western countries and reaching 75-99% in Iranian studies. Data on vitamin D deficiency (25-hydroxyvitamin D serum levels <20 ng/ml) in relation to ART outcomes could be extracted from three studies and included in the meta-analysis, yielding a common risk ratio (RR) of 0.89 (95% CI 0.53-1.49) and showing a lower but not statistically significant likelihood of clinical pregnancy for vitamin-D-deficient women compared with vitamin-D-sufficient patients. In conclusion, there is insufficient evidence to support the routine assessment of vitamin D status to predict the clinical pregnancy rate in couples undergoing ART. The partly conflicting results of the available studies, potentially explaining the lack of statistical significance for a negative influence of vitamin D deficiency on clinical pregnancy rate, are likely secondary to confounders

  12. Toward a statewide health information technology center (abbreviated version).

    PubMed

    Sittig, Dean F; Joe, John C

    2010-11-01

    With the passage of The American Reinvestment and Recovery Act of 2009 that includes the Health Care Information Technology for Economic & Clinical Health Act, the opportunity for states to develop a Health Information Technology Center (THITC) has emerged. The Center provides the intellectual, financial, and technical leadership along with the governance and oversight for all health information technology-related activities in the state. This Center would be a free-standing, not-for-profit, public-private partnership that would be responsible for operating one or more (in large states) Regional Health Information Technology Extension Centers (Extension Centers) along with several Regional Health Information Exchanges (HIEs) and one or more Regional Health Information Data Centers (Data Centers). We believe that if these features and functions could be developed, deployed, and integrated statewide, the health and welfare of the citizens of the state could be improved while simultaneously reducing the costs associated with the provision of care.

  13. Applied technology center business plan and market survey

    NASA Technical Reports Server (NTRS)

    Hodgin, Robert F.; Marchesini, Roberto

    1990-01-01

    Business plan and market survey for the Applied Technology Center (ATC), computer technology transfer and development non-profit corporation, is presented. The mission of the ATC is to stimulate innovation in state-of-the-art and leading edge computer based technology. The ATC encourages the practical utilization of late-breaking computer technologies by firms of all variety.

  14. Johnson Space Center Research and Technology 1997 Annual Report

    NASA Technical Reports Server (NTRS)

    1998-01-01

    This report highlights key projects and technologies at Johnson Space Center for 1997. The report focuses on the commercial potential of the projects and technologies and is arranged by CorpTech Major Products Groups. Emerging technologies in these major disciplines we summarized: solar system sciences, life sciences, technology transfer, computer sciences, space technology, and human support technology. Them NASA advances have a range of potential commercial applications, from a school internet manager for networks to a liquid metal mirror for optical measurements.

  15. [Assisted Reproductive Technology in Female Transplant Recipients: Experience of a Reproductive Medicine Unit and Literature Review].

    PubMed

    Vale-Fernandes, Emídio; Póvoa, Ana Margarida; Soares, Sandra; Calejo, Lucinda; Xavier, Pedro; Sousa, Sónia; Beires, Jorge; Montenegro, Nuno

    2016-01-01

    Diseases in end stage typically occur with hypothalamic-pituitary-ovarian axis disorders, with consequent anovulation and infertility. The solid organ transplantation increased survival of patients with end-stage organs disease and the vast majority of women improve their reproductive capacity after transplantation. Although adoption can always be a possibility, the transplanted infertile woman has the right to self-reproductive determination using assisted reproductive techniques. While it is known that pregnancies in transplantedwomen are at high risk, there is no evidence of differences in pregnancy outcome in pregnant transplanted subject to technical, compared with spontaneous pregnancies. The use of assisted reproductive techniques in transplanted women is a medical, ethical and psychosocial challenge, whose approach must be multidisciplinary, to ensure reproductive success without compromising the function of the transplanted organ or maternal health, allowing the birth of a healthy child. The literature remains scarce. Three clinical cases are presented.

  16. The Learner-Centered Paradigm of Education: Roles for Technology

    ERIC Educational Resources Information Center

    Reigeluth, Charles M.

    2014-01-01

    The learner-centered paradigm of education requires very different roles for technology, as well as for teachers and students, compared with the teacher-centered paradigm. Rather than almost exclusively serving the teacher for teaching, technology primarily serves the student for learning. It does so through four major roles: (1) keeping records…

  17. Validating a Technology Enhanced Student-Centered Learning Model

    ERIC Educational Resources Information Center

    Kang, Myunghee; Hahn, Jungsun; Chung, Warren

    2015-01-01

    The Technology Enhanced Student Centered Learning (TESCL) Model in this study presents the core factors that ensure the quality of learning in a technology-supported environment. Although the model was conceptually constructed using a student-centered learning framework and drawing upon previous studies, it should be validated through real-world…

  18. Information and Library Programs at the Technology Application Center (TAC).

    ERIC Educational Resources Information Center

    Burch, Eugene

    The Technology Application Center (TAC) at the University of New Mexico is one of six National Aeronautics and Space Administration (NASA) regional dissemination centers originally established to disseminate NASA technology to private industry on a regional basis. A fee is charged for TAC's services so it has been market oriented and has sought to…

  19. Research and technology, 1984: Marshall Space Flight Center

    NASA Technical Reports Server (NTRS)

    Moorehead, T. W. (Editor)

    1984-01-01

    The Marshall Space Flight Center conducts research programs in space sciences, materials processing in space, and atmospheric sciences, as well as technology programs in such areas as propulsion, materials, processes, and space power. This Marshall Space Flight Center 1984 Annual Report on Research and Technology contains summaries of the more significant scientific and technical results obtained during FY-84.

  20. Reproduction and growth in American robins at the Feed Materials Production Center

    SciTech Connect

    Osborne, D.R.; Jones, F.A. . Dept. of Zoology)

    1991-01-01

    Birds have been useful in environmental monitoring within forest ecosystems and at a variety of industrial sites. Growth analyses have been shown to be a sensitive measure of environmental stress in gulls, eagles, and in passerine birds. As part of an intensive year-long baseline ecological study investigations were initiated in late spring 1987 in order to characterize growth and reproductive success in Mourning Doves (Zenaida macroura) and American Robins (Turdus migratorius) at the Feed Materials Production Center (FMPC). The current study was initiated in order to determine whether the pattern of suppressed growth and reproduction in FMPC birds still existed onsite. We selected only American robins (Turdus migratorius) for study because they appeared the most severely affected in 1987. 44 refs., 3 figs., 3 tabs.

  1. Epigenetics and assisted reproductive technology: a call for investigation.

    PubMed

    Niemitz, Emily L; Feinberg, Andrew P

    2004-04-01

    A surprising set of recent observations suggests a link between assisted reproductive technology (ART) and epigenetic errors--that is, errors involving information other than DNA sequence that is heritable during cell division. An apparent association with ART was found in registries of children with Beckwith-Wiedemann syndrome, Angelman syndrome, and retinoblastoma. Here, we review the epidemiology and molecular biology behind these studies and those of relevant model systems, and we highlight the need for investigation of two major questions: (1) large-scale case-control studies of ART outcomes, including long-term assessment of the incidence of birth defects and cancer, and (2) investigation of the relationship between epigenetic errors in both offspring and parents, the specific methods of ART used, and the underlying infertility diagnoses. In addition, the components of proprietary commercial media used in ART procedures must be fully and publicly disclosed, so that factors such as methionine content can be assessed, given the relationship in animal studies between methionine exposure and epigenetic changes.

  2. Assisted reproductive technology in China: compliance and non-compliance

    PubMed Central

    2014-01-01

    According to the WHO, infertility and sterility will be the third-most serious disease worldwide in the 21st century, after cancer and cardiovascular diseases. In contrast to developed countries, assisted reproductive technology (ART) were not offered in China until the mid-1980s with the first in vitro fertilization (IVF) infant born in Taiwan in 1985, then Hong Kong in 1986, and mainland China in 1988, respectively. Since those inceptions, the practice of ART in China has evoked a variety of social, cultural, political and one-child policy responses that have resulted in restrictions on the number of IVF cycles performed annually. According to recent survey, an estimate 40-50 million women and 45 million men suffered from infertility, which is estimated that more than ten million Chinese infertile couples require ART treatment. However, it has limited access to ART facilities, many of them may not have a child are whirling to all types of fertility therapies. Exposure to radiation, pesticides and other environmental pollutants, work-related stress and unhealthy lifestyles are believed to contribute to the increasing incidence of infertility in China. The aim of this first report is to provide China nationwide ART data and government policy in compliance and 
non-compliance, particularly related to family plan policy in China. PMID:26835327

  3. Association between Thrombophilia and Repeated Assisted Reproductive Technology Failures

    PubMed Central

    Hamdi, Kobra; Vaezi, Maryam; Dagigazar, Behrooz; Mehrzad Sadagiani, Mahzad; Farzadi, Laya; Pashaei-Asl, Maryam

    2012-01-01

    Purpose: This study was performed to investigate the incidence of thrombophilic gene mutations in repeated assisted reproductive technology (ART) failures. Methods: The prevalence of mutated genes in the patients with a history of three or more previous ART failures was compared with the patients with a history of successful pregnancy following ARTs. The study group included 70 patients, 34 with three or more previously failed ARTs (A) and control group consisted of 36 patients with successful pregnancy following ARTs (B). All patients were tested for the presence of mutated thrombophilic genes including factor V Leiden (FVL), Methylenetetrahydrofolate reductase (MTHFR) and Prothrombin (G20210A) using real-time polymerase chain reaction (RT- PCR). Results: Mutation of FVL gene was detected in 5.9% women of group A (2 of 34) compared with 2.8% women (1 of 36) of control group (P = 0.6). Mutation of MTHFR gene was found in 35.3% (12 cases) as compared with 50% (18 cases) of control (35.3% versus 50%; P = 0.23). Regarding Prothrombin, only control group had 5.6% mutation (P = 0.49). No significant differences were detected in the incidences of FVL, Prothrombin and MTHFR in the study group A compared with the control group B. Conclusion: The obtained results suggest that thrombophilia does not have a significant effect in ART failures. PMID:24312798

  4. Assisted reproductive technologies and equity of access issues.

    PubMed

    Peterson, M M

    2005-05-01

    In Australia and other countries, certain groups of women have traditionally been denied access to assisted reproductive technologies (ARTs). These typically are single heterosexual women, lesbians, poor women, and those whose ability to rear children is questioned, particularly women with certain disabilities or who are older. The arguments used to justify selection of women for ARTs are most often based on issues such as scarcity of resources, and absence of infertility (in lesbians and single women), or on social concerns: that it "goes against nature"; particular women might not make good mothers; unconventional families are not socially acceptable; or that children of older mothers might be orphaned at an early age. The social, medical, legal, and ethical reasoning that has traditionally promoted this lack of equity in access to ARTs, and whether the criteria used for client deselection are ethically appropriate in any particular case, are explored by this review. In addition, the issues of distribution and just "gatekeeping" practices associated with these sensitive medical services are examined.

  5. Emerging Technologies: Applications and Implications for School Library Media Centers.

    ERIC Educational Resources Information Center

    Craver, Kathleen W.

    This paper examines emerging information technologies and their implications for school library media centers. Because of the fluctuating situation regarding new innovations, only emerging technologies that specialists believe will occur within the next 5 to 10 years are discussed. For each technology mentioned, a brief description is given…

  6. The National Space Science and Technology Center (NSSTC)

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The National Space Science and Technology Center (NSSTC), located in Huntsville, Alabama, is a laboratory for cutting-edge research in selected scientific and engineering disciplines. The major objectives of the NSSTC are to provide multiple fields of expertise coming together to solve solutions to science and technology problems, and gaining recognition as a world-class science research organization. The center, opened in August 2000, focuses on space science, Earth sciences, information technology, optics and energy technology, biotechnology and materials science, and supports NASA's mission of advancing and communicating scientific knowledge using the environment of space for research. In addition to providing basic and applied research, NSSTC, with its student participation, also fosters the next generation of scientists and engineers. NSSTC is a collaborated effort between NASA and the state of Alabama through the Space Science and Technology alliance, a group of six universities including the Universities of Alabama in Huntsville (UAH),Tuscaloosa (UA), and Birmingham (UAB); the University of South Alabama in Mobile (USA);Alabama Agricultural and Mechanical University (AM) in Huntsville; and Auburn University (AU) in Auburn. Participating federal agencies include NASA, Marshall Space Flight Center, the National Oceanic and Atmospheric Administration, the Department of Defense, the National Science Foundation, and the Department of Energy. Industries involved include the Space Science Research Center, the Global Hydrology and Climate Center, the Information Technology Research Center, the Optics and Energy Technology Center, the Propulsion Research Center, the Biotechnology Research Center, and the Materials Science Research Center. This photo shows the completed center with the additional arnex (right of building) that added an additional 80,000 square feet (7,432 square meters) to the already existent NSSTC, nearly doubling the size of the core facility. At

  7. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Hugh W. Rimmer

    2003-11-15

    The U.S. is the largest producer of mining products in the world. In 1999, U.S. mining operations produced $66.7 billion worth of raw materials that contributed a total of $533 billion to the nation's wealth. Despite these contributions, the mining industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Much of the research to be conducted with Cooperative Agreement funds will be longer-term, high-risk, basic research and will be carried out in five broad areas: (a) Solid-solid separation (b) Solid-liquid separation (c) Chemical/Biological Extraction (d) Modeling and Control, and (e) Environmental Control. Distribution of funds is being handled via competitive solicitation of research proposals through Site Coordinators at the seven member universities. The first of these solicitations, referred to as the CAST II-Round 1 RFP, was issued on October 28, 2002. Thirty-eight proposals were received by the December 10, 2002 deadline for this RFP-eleven (11) Solid-Solid Separation, seven (7) Solid-Liquid Separation, ten (10) Chemical/Biological Extraction, six (6) Modeling & Control and four (4) Environmental Control. These were first reviewed and ranked by a group of technical reviewers (selected primarily from industry). Based on these reviews, and an assessment of overall program requirements, the CAST Technical Committee made an initial selection/ranking of proposals and forwarded these to the DOE/NETL Project Officer for final review and approval. This process took some 7 months to complete but 17 projects (one joint) were in place at the constituent universities (three at Virginia Tech, two at West Virginia University, three at University of Kentucky

  8. Assisted Reproductive Technology and Early Intervention Program Enrollment

    PubMed Central

    Gopal, Daksha; Cabral, Howard; Belanoff, Candice; Declercq, Eugene R.; Kotelchuck, Milton; Luke, Barbara; Stern, Judy E.

    2016-01-01

    OBJECTIVES: We examined the prevalence of Early Intervention (EI) enrollment in Massachusetts comparing singleton children conceived via assisted reproductive technology (ART), children born to mothers with indicators of subfertility but no ART (Subfertile), and children born to mothers who had no indicators of subfertility and conceived naturally (Fertile). We assessed the natural direct effect (NDE), the natural indirect effect (NIE) through preterm birth, and the total effect of ART and subfertility on EI enrollment. METHODS: We examined maternal and infant characteristics among singleton ART (n = 6447), Subfertile (n = 5515), and Fertile (n = 306 343) groups and characteristics associated with EI enrollment includingpreterm birth using χ2 statistics (α = 0.05). We estimated the NDE and NIE of the ART–EI enrollment relationship by fitting a model for enrollment, conditional on ART, preterm and the ART-preterm delivery interaction, and covariates. Similar analyses were conducted by using Subfertile as the exposure. RESULTS: The NDE indicated that the odds of EI enrollment were 27% higher among the ART group (odds ratioNDE = 1.27; 95% confidence interval (CI): 1.19 – 1.36) and 20% higher among the Subfertilegroup (odds ratioNDE = 1.20; 95% CI: 1.12 – 1.29) compared with the Fertile group, even if the rate of preterm birth is held constant. CONCLUSIONS: Singleton children conceived through ART and children of subfertile mothers both have elevated risks of EI enrollment. These findings have implications for clinical providers as they counsel women about child health outcomes associated with ART or subfertility. PMID:26908668

  9. Biological Semiconductors | NCI Technology Transfer Center | TTC

    Cancer.gov

    The National Cancer Institute's Cancer Diagnostic Program and the Food and Drug Administration's Center for Devices and Radiological Health is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize biological semiconductors as diagnostic sensors.

  10. Technology at the "Center for Two Learners"

    ERIC Educational Resources Information Center

    Dismukes, Delisa; Yarbrough, Sondra; Zenanko, Marsha; Zenanko, Mike

    2004-01-01

    In this paper, an early component of the teacher education practicum program in the College of Education and Professional Studies at Jacksonville State University is described. This program includes an on-campus one-on-one tutorial that is facilitated through the Teaching/Learning Center (T/LC). The T/LC was established so that the JSU College of…

  11. Marshall Space Flight Center ECLSS technology activities

    NASA Technical Reports Server (NTRS)

    Wieland, Paul

    1990-01-01

    Viewgraphs on Environmental Control and Life Support System (ECLSS) technology activities are presented. Topics covered include: analytical development; ECLSS modeling approach; example of water reclamation modeling needs; and hardware development and testing.

  12. Ames Research Center Research and Technology 2000

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This report highlights the challenging work accomplished during fiscal year 2000 by Ames research scientists,engineers, and technologists. It discusses research and technologies that enable the Information Age, that expand the frontiers of knowledge for aeronautics and space, and that help to maintain U.S. leadership in aeronautics and space research and technology development. The accomplishments are grouped into four categories based on four of NASA's Strategic Enterprises: Aerospace Technology, Space Science, Biological and Physical Research, and Earth Science. The primary purpose of this report is to communicate knowledge-to inform our stakeholders, customer, and partners, and the people of the United States about the scope and diversity of Ames' mission,the nature of Ames' research and technolog) activities,and the stimulating challenges ahead. The accomplishments cited illustrate the contributions that Ames is willing to improve the quality of life for our citizens and the economic position of the United States in the world marketplace.

  13. The National Space Science and Technology Center (NSSTC)

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The National Space Science and Technology Center (NSSTC), located in Huntsville, Alabama, is a laboratory for cutting-edge research in selected scientific and engineering disciplines. The major objectives of the NSSTC are to provide multiple fields of expertise coming together to solve solutions to science and technology problems, and gaining recognition as a world-class science research organization. The center, opened in August 2000, focuses on space science, Earth sciences, information technology, optics and energy technology, biotechnology and materials science, and supports NASA's mission of advancing and communicating scientific knowledge using the environment of space for research. In addition to providing basic and applied research, NSSTC, with its student participation, also fosters the next generation of scientists and engineers. NSSTC is a collaborated effort between NASA and the state of Alabama through the Space Science and Technology alliance, a group of six universities including the Universities of Alabama in Huntsville (UAH),Tuscaloosa (UA), and Birmingham (UAB); the University of South Alabama in Mobile (USA); Alabama Agricultural and Mechanical University (AM) in Huntsville; and Auburn University (AU) in Auburn. Participating federal agencies include NASA, Marshall Space Flight Center, the National Oceanic and Atmospheric Administration, the Department of Defense, the National Science Foundation, and the Department of Energy. Industries involved include the Space Science Research Center, the Global Hydrology and Climate Center, the Information Technology Research Center, the Optics and Energy Technology Center, the Propulsion Research Center, the Biotechnology Research Center, and the Materials Science Research Center. An arnex, scheduled for completion by summer 2002, will add an additional 80,000 square feet (7,432 square meters) to NSSTC nearly doubling the size of the core facility. At full capacity, the completed NSSTC will top 200

  14. The Manned Spacecraft Center and medical technology

    NASA Technical Reports Server (NTRS)

    Johnston, R. S.; Pool, S. L.

    1974-01-01

    A number of medically oriented research and hardware development programs in support of manned space flights have been sponsored by NASA. Blood pressure measuring systems for use in spacecraft are considered. In some cases, complete new bioinstrumentation systems were necessary to accomplish a specific physiological study. Plans for medical research during the Skylab program are discussed along with general questions regarding space-borne health service systems and details concerning the Health Services Support Control Center.

  15. Research and technology of the Langley Research Center

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Descriptions of the research and technology activities at the Langley Research Center are given. Topics include laser development, aircraft design, aircraft engines, aerodynamics, remote sensing, space transportation systems, and composite materials.

  16. SAVANNAH RIVER TECHNOLOGY CENTER MONTHLY REPORT AUGUST 1992

    SciTech Connect

    Ferrell, J.M.

    1999-06-21

    'This monthly report summarizes Programs and Accomplishments of the Savannah River Technology Center in support of activities at the Savannah River Site. The following categories are addressed: Reactor, Tritium, Separations, Environmental, Waste Management, General, and Items of Interest.'

  17. The 1991 Marshall Space Flight Center research and technology

    NASA Technical Reports Server (NTRS)

    1991-01-01

    A compilation of 194 articles addressing research and technology activities at the Marshall Space Flight Center (MSFC) is given. Activities are divided into three major areas: advanced studies addressing transportation systems, space systems, and space science activities conducted primarily in the Program Development Directorate; research tasks carried out in the Space Science Laboratory; and technology programs hosted by a wide array of organizations at the Center. The theme for this year's report is 'Building for the Future'.

  18. Research and technology of the Lyndon Johnson Space Center

    NASA Technical Reports Server (NTRS)

    1989-01-01

    Johnson Space Center accomplishments in new and advanced concepts during 1988 are highlighted. This year, reports are grouped in sections Space System Technology, Solar System Sciences, Space Transportation Technology, and Medical Sciences. Summary sections describing the role of Johnson Space Center in each program are followed by descriptions of significant tasks. Descriptions are suitable for external consumption, free of technical jargon, and illustrated to increase ease of comprehension.

  19. A feasibility study for a manufacturing technology deployment center

    SciTech Connect

    Not Available

    1994-10-31

    The Automation & Robotics Research Institute (ARRI) and the Texas Engineering Extension Service (TEEX) were funded by the U.S. Department of Energy to determine the feasibility of a regional industrial technology institute to be located at the Superconducting Super Collider (SSC) Central Facility in Waxahachie, Texas. In response to this opportunity, ARRI and TEEX teamed with the DOE Kansas City Plant (managed by Allied Signal, Inc.), Los Alamos National Laboratory (managed by the University of California), Vought Aircraft Company, National Center for Manufacturing Sciences (NCMS), SSC Laboratory, KPMG Peat Marwick, Dallas County Community College, Navarro Community College, Texas Department of Commerce (TDOC), Texas Manufacturing Assistance Center (TMAC), Oklahoma Center for the Advancement of Science and Technology, Arkansas Science and Technology Authority, Louisiana Productivity Center, and the NASA Mid-Continent Technology Transfer Center (MCTTC) to develop a series of options, perform the feasibility analysis and secure industrial reviews of the selected concepts. The final report for this study is presented in three sections: Executive Summary, Business Plan, and Technical Plan. The results from the analysis of the proposed concept support the recommendation of creating a regional technology alliance formed by the states of Texas, New Mexico, Oklahoma, Arkansas and Louisiana through the conversion of the SSC Central facility into a Manufacturing Technology Deployment Center (MTDC).

  20. Phosphor Technology Center of Excellence: research, education, industrial interactions

    NASA Astrophysics Data System (ADS)

    Summers, Christopher J.

    1994-04-01

    A review is given of the participants and the research, education and industrial mission of the center. The Phosphor Technology Center of Excellence is established at the Georgia Institute of Technology with the University of Georgia, University of Florida, Pennsylvania State University, David Sarnoff Research Center and the American Display Consortium being charter members. The research mission addresses short, medium and long term needs in five technological areas; cathode ray tube, electroluminescence, field emission devices, plasma display panels and active-matrix liquid crystal display back-light phosphors through interactive university/industry technology groups. Outreach activities include the establishment of a phosphor database, industry analysis and short courses in addition to the conventional university education role. Specific science and technology programs are briefly described.

  1. Use of polarized light microscopy in porcine reproductive technologies.

    PubMed

    Caamaño, J N; Maside, C; Gil, M A; Muñoz, M; Cuello, C; Díez, C; Sánchez-Osorio, J R; Martín, D; Gomis, J; Vazquez, J M; Roca, J; Carrocera, S; Martinez, E A; Gómez, E

    2011-09-01

    The meiotic spindle in the oocyte is composed of microtubules and plays an important role during chromosome alignment and separation at meiosis. Polarized light microscopy (PLM) could be useful for a non-invasive evaluation of the meiotic spindle and may allow removal of nuclear structures without fluorochrome staining and ultraviolet exposure. In this study, PLM was used to assess its potential application in porcine reproductive technologies. The objectives of the present study were to assess the efficiency of PLM to detect microtubule-polymerized protein in in vitro-matured porcine oocytes; to examine its effects on the oocyte developmental competence; to select oocytes based on the presence of the meiotic spindle detected by PLM; and to assess the efficiency oocyte enucleation assisted with PLM. In the first experiment, the presence of microtubule-polymerized protein was assessed and confirmed in oocytes (n = 117) by immunostaining and chromatin detection. In the second experiment, oocytes (n = 160) were exposed or not (controls) to PLM for 10 minutes, and then parthenogenetically activated and cultured in vitro. In the third experiment, development competence of oocytes with a positive or negative signal to PLM was analyzed after in vitro fertilization. Finally, oocytes (n = 54) were enucleated using PLM as a tool to remove the meiotic spindle. A positive PLM signal was detected in 98.2 % of the oocytes, which strongly correlated (r = 1; p < 0.0001) with the presence of microtubule-polymerized protein as confirmed by immunostaining. Oocytes exposed to PLM did not differ significantly from controls on cleavage, total blastocyst, expanded blastocyst rates and total cell numbers. The percentage of oocytes at the MII stage and blastocyst formation rate in the negative PLM group significantly differed from control and PLM positive groups. Overall efficiency of spindle removal using the PLM-Oosight system was 92.6%. These results suggest that polarized light

  2. Cryopreservation and delayed embryo transfer-assisted reproductive technology registry and reporting implications.

    PubMed

    Doody, Kevin J

    2014-07-01

    Clinics performing assisted reproductive technology (ART) procedures have collected data via registry and publicly reported pregnancy outcomes for more than 25 years. During this time, the practice of ART has changed considerably with frozen embryo transfer (FET) procedures contributing an increasing proportion of live births. Cycles initiated with the intent of embryo banking for the purpose of fertility preservation have been excluded from these public reports, because pregnancy outcomes are not immediately available. An unintended consequence of the common sense handling of fertility preservation has been that cycles performed with intentional short-term cryopreservation of all embryos for other indications have also been excluded from the report. Over the last few years, cryopreservation with short-term delayed transfer increasingly has been performed for reasons other than fertility preservation. The pregnancy outcomes of these cycles are expected within a reasonable time frame and should be transparently reported. The Society for Assisted Reproductive Technology has collaborated with the Centers for Disease Control and Prevention to "recapture" these cycles for the public reports. This recapture is done by linking the FET cycles to the stimulation cycles from which the embryos were derived and by changing the labels of the outcome success metrics. Stimulations using ART, initiated for the purpose of transferring embryos within 1 year will be included in the report despite any prospective intent to freeze all eggs or embryos. A positive outcome will be reported when a live birth results from the first embryo transfer following stimulation ("primary transfer"). Linkage of ovarian stimulation and egg-retrieval procedures to FET will also allow development of other success metrics to further benefit fertility patients.

  3. Effect of Embryo Banking on U.S. National Assisted Reproductive Technology Live Birth Rates

    PubMed Central

    Kushnir, Vitaly A.; Barad, David H.; Albertini, David F.; Darmon, Sarah K.; Gleicher, Norbert

    2016-01-01

    Background Assisted Reproductive Technology (ART) reports generated by the Centers for Disease Control and Prevention (CDC) exclude embryo banking cycles from outcome calculations. Methods We examined data reported to the CDC in 2013 for the impact of embryo banking exclusion on national ART outcomes by recalculating autologous oocyte ART live birth rates. Inflation of reported fresh ART cycle live birth rates was assessed for all age groups of infertile women as the difference between fresh cycle live births with reference to number of initiated fresh cycles (excluding embryo banking cycles), as typically reported by the CDC, and fresh cycle live births with reference to total initiated fresh ART cycles (including embryo banking cycles). Results During 2013, out of 121,351 fresh non-donor ART cycles 27,564 (22.7%) involved embryo banking. The proportion of banking cycles increased with female age from 15.5% in women <35 years to 56.5% in women >44 years. Concomitantly, the proportion of thawed cycles decreased with advancing female age (P <0.0001). Exclusion of embryo banking cycles led to inflation of live birth rates in fresh ART cycles, increasing in size in parallel to advancing female age and utilization of embryo banking, reaching 56.3% in women age >44. The inflation of live birth rates in thawed cycles could not be calculated from the publically available CDC data but appears to be even greater. Conclusions Utilization of embryo banking increased during 2013 with advancing female age, suggesting a potential age selection bias. Exclusion of embryo banking cycles from national ART outcome reports significantly inflated national ART success rates, especially among older women. Précis Exclusion of embryo banking cycles from US National Assisted Reproductive Technology outcome reports significantly inflates reported success rates especially in older women. PMID:27159215

  4. Computers & Technology in School Library Media Centers. Professional Growth Series.

    ERIC Educational Resources Information Center

    Bucher, Katherine Toth

    Technology is arriving in school libraries in unprecedented quantities, resulting in many changes in the school library media center. While most librarians agree that technology is wonderful, many are feeling the stress of rapid change and coping with the decisions made by educational policy makers. This looseleaf notebook, written for the novice,…

  5. Wind Energy at NREL's National Wind Technology Center

    ScienceCinema

    None

    2016-07-12

    It is a pure, plentiful natural resource. Right now wind is in high demand and it holds the potential to transform the way we power our homes and businesses. NREL is at the forefront of wind energy research and development. NREL's National Wind Technology Center (NWTC) is a world-class facility dedicated to accelerating and deploying wind technology.

  6. The Advanced Technology Environmental Education Center Summer Fellows Institute.

    ERIC Educational Resources Information Center

    Depken, Diane E.; Zeman, Catherine L.; Lensch, Ellen Kabat; Brown, Edward J.

    2002-01-01

    Describes the background, activities, and outcomes of the Advanced Technology Environmental Education Center (ATEEC) and its Summer Fellows Institutes as a model for disciplinary and cross-disciplinary infusion of environmental science and technology content, curriculum, and methods into the classroom. Presents experiences, themes, and activities…

  7. Research and technology highlights of the Lewis Research Center

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Highlights of research accomplishments of the Lewis Research Center for fiscal year 1984 are presented. The report is divided into four major sections covering aeronautics, space communications, space technology, and materials and structures. Six articles on energy are included in the space technology section.

  8. Educational Technology Center Fourth Year Report. TR88-5.

    ERIC Educational Resources Information Center

    Educational Technology Center, Cambridge, MA.

    This report enumerates the activities of the Educational Technology Center (ETC) during 1987. The guide's theme for the year was Teaching with Technology. The report includes brief descriptions of five different types of research projects by area. In science education, the projects concerned with weight and density, heat and temperature, and the…

  9. Research & Technology Report Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Soffen, Gerald A. (Editor); Truszkowski, Walter (Editor); Ottenstein, Howard (Editor); Frost, Kenneth (Editor); Maran, Stephen (Editor); Walter, Lou (Editor); Brown, Mitch (Editor)

    1995-01-01

    The main theme of this edition of the annual Research and Technology Report is Mission Operations and Data Systems. Shifting from centralized to distributed mission operations, and from human interactive operations to highly automated operations is reported. The following aspects are addressed: Mission planning and operations; TDRSS, Positioning Systems, and orbit determination; hardware and software associated with Ground System and Networks; data processing and analysis; and World Wide Web. Flight projects are described along with the achievements in space sciences and earth sciences. Spacecraft subsystems, cryogenic developments, and new tools and capabilities are also discussed.

  10. The Oklahoma Health Information Technology Regional Extension Center.

    PubMed

    Bratzler, Dale W

    2010-09-01

    With the passage of the Health Information Technology for Economic and Clinical Health Act (HITECH) the government has created a network of Health Information Technology Regional Extension Centers to provide direct technical assistance to primary care providers in small practices to adopt and meaningfully use electronic health records (EHR). Regional Extension Centers will work directly with practitioner offices to identify effective strategies to select, implement, and meaningfully use certified EHR technology. The Oklahoma Foundation for Medical Quality (OFMQ) was awarded the cooperative agreement to serve as the Regional Extension Center for the state, and is actively recruiting practices to provide support on implementation of an EHR. There is some urgency for physician practices to consider work with the Regional Extension Center since the federal matching funding for the program will be substantially reduced beginning in 2012, and because the incentive funds for a practice that adopts and meaningfully uses an EHR are reduced beginning in 2013.

  11. SciDAC Visualization and Analytics Center for Enabling Technologies

    SciTech Connect

    Joy, Kenneth I.

    2014-09-14

    This project focuses on leveraging scientific visualization and analytics software technology as an enabling technology for increasing scientific productivity and insight. Advances in computational technology have resulted in an "information big bang," which in turn has created a significant data understanding challenge. This challenge is widely acknowledged to be one of the primary bottlenecks in contemporary science. The vision for our Center is to respond directly to that challenge by adapting, extending, creating when necessary and deploying visualization and data understanding technologies for our science stakeholders. Using an organizational model as a Visualization and Analytics Center for Enabling Technologies (VACET), we are well positioned to be responsive to the needs of a diverse set of scientific stakeholders in a coordinated fashion using a range of visualization, mathematics, statistics, computer and computational science and data management technologies.

  12. GHG MITIGATION TECHNOLOGY PERFORMANCE EVALUATIONS UNDERWAY AT THE GHG TECHNOLOGY VERIFICATION CENTER

    EPA Science Inventory

    The paper outlines the verification approach and activities of the Greenhouse Gas (GHG) Technology Verification Center, one of 12 independent verification entities operating under the U.S. EPA-sponsored Environmental Technology Verification (ETV) program. (NOTE: The ETV program...

  13. Technology Transfer Center to Assume Patenting and Licensing Responsibilities | Poster

    Cancer.gov

    The NCI Technology Transfer Center (TTC) is undergoing a reorganization that will bring patenting and licensing responsibilities to the Shady Grove and Frederick offices by October 2015. The reorganization is a result of an effort begun in 2014 by NIH to improve the organizational structure of technology transfer at NIH to meet the rapid rate of change within science, technology, and industry, and to better align the science and laboratory goals with the licensing and patenting process.

  14. 78 FR 77662 - Notice of Availability (NOA) for General Purpose Warehouse and Information Technology Center...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... Technology Center Construction (GPW/IT)--Tracy Site-- Environmental Assessment (EA); Finding of No... General Purpose Warehouse and Information Technology Center Construction (GPW/IT)--Tracy Site... the General Purpose Warehouse and Information Technology Center Construction (GPW/IT)--Tracy...

  15. Risk disparities in the globalisation of assisted reproductive technology: the case of Asia.

    PubMed

    Ha, Jung-Ok

    2013-01-01

    This paper analyses the disparities in risks associated with biomedical technology focusing on the results of assisted reproductive technology (ART). ART among biomedical technologies transferred to Asia is a representative case that reveals in its clinical use and related scientific research the global politics of technology. This study notes the global politics at work in the recognition of and reaction to such risks. While many Asian countries aggressively pursue technological development, weak legislative and administrative regulations have created various problems and controversial cases. This study asserts that risks associated with technology are characterised as social facts not natural ones or mere 'side effects', since technological development and risk are closely intertwined.

  16. Right to assisted reproductive technology: overcoming infertility in low-resource countries.

    PubMed

    Inhorn, Marcia C

    2009-08-01

    This article examines the high prevalence of primary and secondary infertility in low-resource countries. Provision of assisted reproductive technology (ART) to overcome both female and male infertility is in line with the reproductive rights agenda developed at the International Conference on Population and Development (ICPD) in Cairo 15 years ago. In addition to the right to control fertility, reproductive rights must encompass the right to facilitate fertility when fertility is threatened. Facilitation of fertility may require resort to ART, among both men and women. Egypt is highlighted as a positive example of progress in this regard.

  17. GREENHOUSE GAS (GHG) MITIGATION AND MONITORING TECHNOLOGY PERFORMANCE: ACTIVITIES OF THE GHG TECHNOLOGY VERIFICATION CENTER

    EPA Science Inventory

    The paper discusses greenhouse gas (GHG) mitigation and monitoring technology performance activities of the GHG Technology Verification Center. The Center is a public/private partnership between Southern Research Institute and the U.S. EPA's Office of Research and Development. It...

  18. Cryobiology in human assisted reproductive technology. Would Hippocrates approve?

    PubMed

    Bredkjaer, H E; Grudzinskas, J G

    2001-07-01

    and colon? Should we cryopreserve oocytes/sperm/embryos for the purposes of PGD once the markers are available? Cryobiology indeed provides hope now for women and men with neoplastic diseases, who are about to receive oncotherapy for malignancies which inevitably will render them sterile. Men may now freeze epididymal, testicular as well as ejaculatory sperm as ICSI has revolutionalised the treatment of male infertility. It might be likely that testicular tissue from prepubertal boys can be cryopreserved with a reasonable expectation that techniques will soon be developed to effect maturation of spermatogonia in-vivo or in-vitro13. The greatest advance is likely to be for women suffering from reproductive cancer, who may now consider mature and immature oocytes being frozen or vitrified with a reasonable chance of fertilisation by ICSI later, as well as the cryopreservation and storage of ovarian cortex tissue biopsies. Work is proceeding still to refine techniques of in-vitro maturation of frozen-thawed immature oocytes, and the frozen-thawed ovarian cortex tissue slices. The potential benefits will not only be to female fertility for the latter conditions but endocrine disorders as well as by autotransplantation (1999)9. Currently, ovarian tissue banking8 is being considered by women undergoing procedures or treatment which could destroy ovarian function with quite realistic but cautious expectations of preserving ovarian function, but tomorrow women may consider banking ovarian tissue as insurance against childlessness because of the risk of disorders in the reproductive tract (endometriosis, simple recurrent ovarian cysts) and even advancing years. For those who have conceived with surplus oocytes cryopreserved, anonymous oocyte donation is a possibility for the solution of ethical and legal problems. All over Europe, the age of women having their first child is dramatically increasing now being in their late twenties, with likely significant implications in the

  19. Savannah River Site Radiological Technology Center's Efforts Supporting Waste Minimization

    SciTech Connect

    Rosenberger, K. H.; Smith, L. S.; Bates, R. L.

    2003-02-25

    This paper describes the efforts of the newly formed Radiological Technology Center (RTC) at the Department of Energy's Savannah River Site (SRS) to support waste minimization. The formation of the RTC was based upon the highly successful ALARA Center at the DOE Hanford Site. The RTC is tasked with evaluation and dissemination of new technologies and techniques for radiological hazard reduction and waste minimization. Initial waste minimization efforts have focused on the promotion of SRS containment fabrication capabilities, new personal protective equipment and use of recyclable versus disposable materials.

  20. The application of reproductive technologies to natural populations of red deer.

    PubMed

    Garde, J J; Martínez-Pastor, F; Gomendio, M; Malo, A F; Soler, A J; Fernández-Santos, M R; Esteso, M C; García, A J; Anel, L; Roldán, E R S

    2006-10-01

    Over the past decade, there has been increasing interest in the application of reproductive technology to the conservation and management of natural populations of deer. The application of assisted reproduction technologies within natural population of deer is in its infancy. However, its future potential is enormous, particularly in relation to genetic management or conservation. This paper reviews the present state of such technologies for a wild subspecies of red deer, the Iberian red deer (Cervus elaphus hispanicus), by discussing the major components of oestrous synchronization, semen collection/cryopreservation and insemination techniques. In addition, findings made during the course of studies on natural populations have enormous potential for the understanding of novel reproductive mechanism that may not be uncovered by livestock or human studies. A summary of these results are also reviewed here.

  1. Application of sperm sorting and associated reproductive technology for wildlife management and conservation.

    PubMed

    O'Brien, J K; Steinman, K J; Robeck, T R

    2009-01-01

    Efforts toward the conservation and captive breeding of wildlife can be enhanced by sperm sorting and associated reproductive technologies such as sperm cryopreservation and artificial insemination (AI). Sex ratio management is of particular significance to species which naturally exist in female-dominated social groups. A bias of the sex ratio towards females of these species will greatly assist in maintaining socially cohesive groups and minimizing male-male aggression. Another application of this technology potentially exists for endangered species, as the preferential production of females can enable propagation of those species at a faster rate. The particular assisted reproductive technology (ART) used in conjunction with sperm sorting for the production of offspring is largely determined by the quality and quantity of spermatozoa following sorting and preservation processes. Regardless of the ART selected, breeding decisions involving sex-sorted spermatozoa should be made in conjunction with appropriate genetic management. Zoological-based research on reproductive physiology and assisted reproduction, including sperm sorting, is being conducted on numerous terrestrial and marine mammals. The wildlife species for which the technology has undergone the most advance is the bottlenose dolphin. AI using sex-sorted fresh or frozen-thawed spermatozoa has become a valuable tool for the genetic and reproductive management of captive bottlenose dolphins with six pre-sexed calves, all of the predetermined sex born to date.

  2. Manufacturing Technology Information Analysis Center: Knowledge Is Strength

    NASA Technical Reports Server (NTRS)

    Safar, Michal

    1992-01-01

    The Center's primary function is to facilitate technology transfer within DoD, other government agencies and industry. The DoD has recognized the importance of technology transfer, not only to support specific weapon system manufacture, but to strengthen the industrial base that sustains DoD. MTIAC uses an experienced technical staff of engineers and information specialists to acquire, analyze, and disseminate technical information. Besides ManTech project data, MTIAC collects manufacturing technology from other government agencies, commercial publications, proceedings, and various international sources. MTIAC has various means of disseminating this information. Much of the technical data is on user accessible data bases. The Center researches and writes a number of technical reports each year and publishes a newsletter monthly. Customized research is performed in response to specific inquiries from government and industry. MTIAC serves as a link between Government and Industry to strengthen the manufacturing technology base through the dissemination of advanced manufacturing information.

  3. Manufacturing Technology Information Analysis Center: Knowledge is strength

    NASA Astrophysics Data System (ADS)

    Safar, Michal

    1992-04-01

    The Center's primary function is to facilitate technology transfer within DoD, other government agencies and industry. The DoD has recognized the importance of technology transfer, not only to support specific weapon system manufacture, but to strengthen the industrial base that sustains DoD. MTIAC uses an experienced technical staff of engineers and information specialists to acquire, analyze, and disseminate technical information. Besides ManTech project data, MTIAC collects manufacturing technology from other government agencies, commercial publications, proceedings, and various international sources. MTIAC has various means of disseminating this information. Much of the technical data is on user accessible data bases. The Center researches and writes a number of technical reports each year and publishes a newsletter monthly. Customized research is performed in response to specific inquiries from government and industry. MTIAC serves as a link between Government and Industry to strengthen the manufacturing technology base through the dissemination of advanced manufacturing information.

  4. Savannah River Technology Center monthly report, March 1995

    SciTech Connect

    1995-03-01

    Short summaries are given on the status of projects within the Savannah River Technology Center covering the following broad topical areas: Tritium; Separations; Environmental studies; Waste management; and General. Studies listed under this last area include: Reactor support; Site robotics support; Robotics for D and D; Robotics for mixed waste operation; Integrated demonstration of an underground storage tank; and Alliance for the Advancement of Robotic Technology (AART).

  5. Association between serum folate and vitamin B-12 and outcomes of assisted reproductive technologies1

    PubMed Central

    Gaskins, Audrey J; Chiu, Yu-Han; Williams, Paige L; Ford, Jennifer B; Toth, Thomas L; Hauser, Russ; Chavarro, Jorge E

    2015-01-01

    Background: Preconceptional folate and vitamin B-12 have been linked to beneficial reproductive outcomes in both natural pregnancies and those after assisted reproductive technology (ART) treatment. Objective: The objective of the study was to evaluate the associations of serum folate and vitamin B-12 with ART outcomes. Design: This analysis included a random sample of 100 women (154 ART cycles) participating in a prospective cohort study [Environment and Reproductive Health (EARTH)] at the Massachusetts General Hospital Fertility Center (2007–2013). Serum folate and vitamin B-12 were measured in blood samples collected between days 3 and 9 of treatment. Generalized estimating equations with adjustment for age, BMI, and race were used to evaluate the association of serum folate and vitamin B-12 with ART outcomes. Results: Women in the highest quartile of serum folate (>26.3 ng/mL) had 1.62 (95% CI: 0.99, 2.65) times the probability of live birth compared with women in the lowest quartile (<16.6 ng/mL). Women in the highest quartile of serum vitamin B-12 (>701 pg/mL) had 2.04 (95% CI: 1.14, 3.62) times the probability of live birth compared with women in the lowest quartile (<439 pg/mL). Suggestive evidence of an interaction was observed; women with serum folate and vitamin B-12 concentrations greater than the median had 1.92 (95% CI: 1.12, 3.29) times the probability of live birth compared with women with folate and vitamin B-12 concentrations less than or equal to the median. This translated into an adjusted difference in live birth rates of 26% (95% CI: 10%, 48%; P = 0.02). Conclusion: Higher serum concentrations of folate and vitamin B-12 before ART treatment were associated with higher live birth rates among a population exposed to folic acid fortification. This trial was registered at clinicaltrials.gov as NCT00011713. PMID:26354529

  6. Overview of Stirling Technology Research at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Wilson, Scott D.; Schifer, Nicholas A.; Williams, Zachary D.; Metscher, Jonathan F.

    2015-01-01

    Stirling Radioisotope Power Systems (RPS) are under development to provide power on future space science missions where robotic spacecraft will orbit, flyby, land or rove using less than a quarter of the plutonium the currently available RPS uses to produce about the same power. Glenn Research Center's (GRC's) newly formulated Stirling Cycle Technology Development Project (SCTDP) continues development of Stirling-based systems and subsystems, which include a flight-like generator and related housing assembly, controller, and convertors. The project also develops less mature technologies under Stirling Technology Research, with a focus on demonstration in representative environments to increase the technology readiness level (TRL). Matured technologies are evaluated for selection in future generator designs. Stirling Technology Research tasks focus on a wide variety of objectives, including increasing temperature capability to enable new environments, reducing generator mass and/or size, improving reliability or system fault tolerance, and developing alternative designs. The task objectives and status are summarized.

  7. Overview of Stirling Technology Research at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Wilson, Scott D.; Schifer, Nicholas A.; Williams, Zachary D.; Metscher, Jonathan F.

    2016-01-01

    Stirling Radioisotope Power Systems (RPSs) are under development to provide power on future space science missions where robotic spacecraft will orbit, fly by, land, or rove using less than a quarter of the plutonium the currently available RPS uses to produce about the same power. NASA Glenn Research Center's newly formulated Stirling Cycle Technology Development Project (SCTDP) continues development of Stirling-based systems and subsystems, which include a flight-like generator and related housing assembly, controller, and convertors. The project also develops less mature technologies under Stirling Technology Research, with a focus on demonstration in representative environments to increase the technology readiness level (TRL). Matured technologies are evaluated for selection in future generator designs. Stirling Technology Research tasks focus on a wide variety of objectives, including increasing temperature capability to enable new environments, reducing generator mass and/or size, improving reliability and system fault tolerance, and developing alternative designs. The task objectives and status are summarized.

  8. Homocysteine in embryo culture media as a predictor of pregnancy outcome in assisted reproductive technology.

    PubMed

    Boyama, Burcu Aydin; Cepni, Ismail; Imamoglu, Metehan; Oncul, Mahmut; Tuten, Abdullah; Yuksel, Mehmet Aytac; Kervancioglu, Mehmet Ertan; Kaleli, Semih; Ocal, Pelin

    2016-01-01

    The aim of this study was to determine whether homocysteine (hcy) concentrations in embryo culture media correlate with pregnancy outcome in assisted reproductive technology (ART) cycles. Forty patients who underwent single embryo transfer at the infertility clinic of a tertiary care center were recruited for this case-control study. Spent embryo culture media from all patients were collected after single embryo transfer on day 3 (n = 40). Hcy concentrations in embryo culture media were analyzed by enzyme cycling method. Patients were grouped according to the diagnosis of a clinical pregnancy. Sixteen patients were pregnant while 24 patients failed to achieve conception. Mean Hcy levels in the culture media were significantly different between the groups (p < 0.003), as 4.58 ± 1.31 μmol/l in the non-pregnant group and 3.37 ± 0.92 μmol/l in the pregnant group. Receiver operator curve analysis for determining the diagnostic potential of Hcy for pregnancy revealed an area under the curve of 0.792 (confidence interval: 0.65-0.94; p < 0.05). A cut-off value of 3.53 μmol/l was determined with a sensitivity of 83.3%, and a specificity of 68.8%. Lower hcy levels were associated with a better chance of pregnancy and better embryo grades. Hcy may be introduced as an individual metabolomic profiling marker for embryos.

  9. States Monitoring Assisted Reproductive Technology (SMART) Collaborative: data collection, linkage, dissemination, and use.

    PubMed

    Mneimneh, Allison S; Boulet, Sheree L; Sunderam, Saswati; Zhang, Yujia; Jamieson, Denise J; Crawford, Sara; McKane, Patricia; Copeland, Glenn; Mersol-Barg, Michael; Grigorescu, Violanda; Cohen, Bruce; Steele, JoAnn; Sappenfield, William; Diop, Hafsatou; Kirby, Russell S; Kissin, Dmitry M

    2013-07-01

    Assisted reproductive technology (ART) refers to fertility treatments in which both eggs and sperm are handled outside the body. The Centers for Disease Control and Prevention (CDC) oversees the National ART Surveillance System (NASS), which collects data on all ART procedures performed in the United States. The NASS, while a comprehensive source of data on ART patient demographics and clinical procedures, includes limited information on outcomes related to women's and children's health. To examine ART-related health outcomes, CDC and three states (Massachusetts, Florida, and Michigan) established the States Monitoring ART (SMART) Collaborative to evaluate maternal and perinatal outcomes of ART and improve state-based ART surveillance. To date, NASS data have been linked with states' vital records, disease registries, and hospital discharge data with a linkage rate of 90.2%. The probabilistic linkage methodology used in the SMART Collaborative has been validated and found to be both accurate and efficient. A wide breadth of applied research within the Collaborative is planned or ongoing, including examinations of the impact of insurance mandates on ART use as well as the relationships between ART and birth defects and cancer, among others. The SMART Collaborative is working to improve state-based ART surveillance by developing state surveillance plans, establishing partnerships, and conducting data analyses. The SMART Collaborative has been instrumental in creating linked datasets and strengthening epidemiologic and research capacity for improving maternal and infant health programs and evaluating the public health impact of ART.

  10. Obstetric outcomes of monochorionic pregnancies conceived following assisted reproductive technology: A retrospective study

    PubMed Central

    Mascarenhas, Mariano; Kamath, Mohan S.; Muthukumar, K; Mangalaraj, Ann M.; Chandy, Achamma; Aleyamma, TK

    2014-01-01

    OBJECTIVES: The overwhelming numbers of twins following assisted reproductive technology (ART) are dichorionic twins, but monochorionic twins account for around 0.9% of post ART pregnancies. The data for post ART-monochorionic pregnancy outcomes are scarce due to the rarity of this condition. Hence, we evaluated the obstetric outcomes of monochorionic and dichorionic pregnancies conceived on ART. SETTINGS: University teaching hospital. STUDY DESIGN: A case–control study of monochorionic diamniotic (MCDA) and dichorionic diamniotic (DCDA) pregnancies conceived following ART treatment. Charts of all women who conceived following ART from 2008 to 2013 were screened. Among them, the monochorionic twins diagnosed in the first trimester were included and their obstetric outcome was followed-up. For comparison, an equal number of dichorionic twin pregnancies from age and body mass index matched mothers was selected. RESULTS: The baseline clinical characteristics were similar between the two groups. MCDA group had a higher miscarriage rate (50%) than the DCDA group (10%), with three seconds trimester miscarriages in the MCDA group. The live birth rates were lower in the MCDA versus DCDA group (40% vs. 90%). Among triplet pregnancies with a monochorionic component, the live birth rate was only 25%. CONCLUSIONS: Monochorionic pregnancies following ART have poorer obstetric outcomes when compared to dichorionic pregnancies. For monochorionic pregnancies following ART, intensive antenatal surveillance at a tertiary level obstetric and neonatal center may help optimize the outcome. PMID:25191025

  11. Soy food intake and treatment outcomes of women undergoing assisted reproductive technology

    PubMed Central

    Vanegas, Jose C.; Afeiche, Myriam C.; Gaskins, Audrey J.; Mínguez-Alarcón, Lidia; Williams, Paige L.; Wright, Diane L.; Toth, Thomas L.; Hauser, Russ; Chavarro, Jorge E.

    2014-01-01

    Objective To study the relation of dietary phytoestrogens intake and clinical outcomes of women undergoing infertility treatment with assisted reproductive technology (ART). Design Prospective cohort study. Setting Fertility center in an academic hospital. Participants 315 women who collectively underwent 520 ART cycles between 2007 and 2013. Interventions None Outcomes Primary outcomes were implantation, clinical pregnancy and live birth rates per initiated cycle. Results Soy isoflavones intake was positively related to live birth rates in ART. Compared to women who did not consume soy isoflavones, the multivariable-adjusted odds ratios of live birth (95% confidence interval) for women in increasing categories of soy isoflavone intake were 1.32 (0.76–2.27) for women consuming 0.54–2.63 mg/d, 1.87 (1.12–3.14) for women consuming 2.64- 7.55 mg/d, and 1.77 (1.03–3.03) for women consuming 7.56- 27.89 mg/d. Conclusions Dietary soy intake was positively related to the probability of having a live birth during infertility treatment with ART. PMID:25577465

  12. Impact of men's dairy intake on assisted reproductive technology outcomes among couples attending a fertility clinic

    PubMed Central

    Xia, Wei; Chiu, Yu-Han; Afeiche, Myriam C.; Williams, Paige L.; Ford, Jennifer B.; Tanrikut, Cigdem; Souter, Irene; Hauser, Russ; Chavarro, Jorge E.

    2015-01-01

    SUMMARY Intake of full-fat dairy has been linked to lower semen quality but whether this leads to decreased fertility is unknown. To address this question, we prospectively evaluated the association of men's dairy intake with treatment outcomes of subfertile couples undergoing assisted reproductive technology (ART). We followed 142 men from couples undergoing infertility treatment with ART at an academic fertility center between 2007 and 2014. Couples completed dietary assessments prior to treatment, and the female partners underwent a total of 248 ART cycles. Multivariable generalized linear mixed models were used to examine the association of dairy intake with fertilization, implantation, clinical pregnancy and live birth rates adjusting for age, body mass index (BMI), smoking status, total exercise time, dietary patterns, alcohol, caffeine, total energy intake, and female dairy intake. Intake of dairy foods, regardless of their fat content, was not associated with fertilization, implantation, clinical pregnancy, or live birth rates. The adjusted live birth rates (95% Confidence Interval) for couples in increasing quartiles of men's dairy intake were 0.42 (0.25, 0.60), 0.25 (0.13, 0.42), 0.26 (0.15, 0.41), and 0.44 (0.27, 0.63) (p, linear trend = 0.73). Results remained similar after adjustment for female partner intake of dairy foods. Overall, men's dairy intake was not associated with treatment outcomes of couples undergoing ART. PMID:26825777

  13. Association Between Assisted Reproductive Technology Conception and Autism in California, 1997–2007

    PubMed Central

    Fountain, Christine; Zhang, Yujia; Kissin, Dmitry M.; Schieve, Laura A.; Jamieson, Denise J.; Rice, Catherine

    2015-01-01

    Objectives. We assessed the association between assisted reproductive technology (ART) and diagnosed autistic disorder in a population-based sample of California births. Methods. We performed an observational cohort study using linked records from the California Birth Master Files for 1997 through 2007, the California Department of Developmental Services autism caseload for 1997 through 2011, and the Centers for Disease Control and Prevention’s National ART Surveillance System for live births in 1997 through 2007. Participants were all 5 926 251 live births, including 48 865 ART-originated infants and 32 922 cases of autism diagnosed by the Department of Developmental Services. We compared births originated using ART with births originated without ART for incidence of autism. Results. In the full population, the incidence of diagnosed autism was twice as high for ART as non-ART births. The association was diminished by excluding mothers unlikely to use ART; adjustment for demographic and adverse prenatal and perinatal outcomes reduced the association substantially, although statistical significance persisted for mothers aged 20 to 34 years. Conclusions. The association between ART and autism is primarily explained by adverse prenatal and perinatal outcomes and multiple births. PMID:25790396

  14. Timber Lane Tales: Problem-Centered Learning and Technology Integration.

    ERIC Educational Resources Information Center

    Norton, Priscilla; Sprague, Debra

    This exploratory study examined a field-based project in which preservice teacher candidates and faculty collaborated to implement a problem-centered, technology integrated curriculum for a multiage (4th, 5th, and 6th grade) intersession at Timber Lane Elementary School. Content included detective skills such as fingerprinting and handwriting…

  15. Center for Advanced Technology Training (CATT) Feasibility Study.

    ERIC Educational Resources Information Center

    Albuquerque Technical Vocational Inst., NM.

    A study of the feasibility of establishing a Center for Advanced Technology Training (CATT) at the Albuquerque Technical Vocational Institute (TVI Community College, New Mexico) was conducted by members of the Albuquerque business community, government representatives, and college administrators. Phase 1 of the study was an examination of the…

  16. Comprehensive Learning Centers: Using Technology To Supplement the Classroom.

    ERIC Educational Resources Information Center

    Groomes, M. Rudy

    Orangeburg-Calhoun Technical College (OCTC) is a public two-year technical college located in rural South Carolina. Some prominent examples of the use of technology at OCTC include the following: (1) the Health Sciences Satellite Media Center houses software and audiovisual equipment which provides instructional support to seven health science…

  17. Research and technology report of the Langley Research Center

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Highlights of major accomplishments and applications made during the past year at the Langley Research Center are reported. The activities and the contributions of this work toward maintaining United States leadership in aeronautics and space research are also discussed. Accomplishments in the fields of aeronautics and space technology, space science and applications and space transportation systems are discussed.

  18. Tank Automotive Research, Development and Engineering Center (TARDEC) Technology Focus

    DTIC Science & Technology

    2008-07-02

    Unclassified Unclassified 1 Tank Automotive Research, Development and Engineering Center (TARDEC) Technology Focus Report Documentation Page Form...ApprovedOMB No. 0704-0188 Public reporting burden for the collection of information is estimated to average 1 hour per response, including the time for...burden, to Washington Headquarters Services, Directorate for Information Operations and Reports , 1215 Jefferson Davis Highway, Suite 1204, Arlington

  19. Massachusetts Institute of Technology, Plasma Fusion Center, Technical Research Programs

    SciTech Connect

    Davidson, Ronald C.

    1980-08-01

    A review is given of the technical programs carried out by the Plasma Fusion Center. The major divisions of work areas are applied plasma research, confinement experiments, fusion technology and engineering, and fusion systems. Some objectives and results of each program are described. (MOW)

  20. The Role of Community Technology Centers in Promoting Youth Development

    ERIC Educational Resources Information Center

    London, Rebecca A.; Pastor, Manuel, Jr.; Servon, Lisa J.; Rosner, Rachel; Wallace, Antwuan

    2010-01-01

    Recent data suggest that the digital divide between White and minority youth persists, particularly in terms of home access to computers and the Internet. Community technology centers (CTCs) are an important alternative access point, especially for low-income youth of color. Such institutions, however, do much more, providing not just access, but…

  1. Centers for manufacturing technology: Industrial Advisory Committee Review

    SciTech Connect

    1995-10-01

    An advisory committee, composed of senior managers form industrial- sector companies and major manufacturing trade associations and representatives from appropriate educational institutions, meets semi-annually to review and advise the Oak Ridge Centers for Manufacturing Technology (ORCMT) on its economic security program. Individual papers have been indexed separately for the database.

  2. Johnson Space Center Research and Technology 1993 Annual Report

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Johnson Space Center research and technology accomplishments during fiscal year 1993 are described and principle researchers and technologists are identified as contacts for further information. Each of the four sections gives a summary of overall progress in a major discipline, followed by detailed, illustrated descriptions of significant tasks. The four disciplines are Life Sciences, Human Support Technology, Solar Systems Sciences, and Space Systems Technology. The report is intended for technical and management audiences throughout the NASA and worldwide aerospace community. An index lists project titles, funding codes, and principal investigators.

  3. Reproductive biology of the biofuel plant Jatropha curcas in its center of origin

    PubMed Central

    Rincón-Rabanales, Manuel; Vargas-López, Laura I.; Adriano-Anaya, Lourdes; Salvador-Figueroa, Miguel

    2016-01-01

    In this work, we studied the main characteristics of flowering, reproductive system and diversity of pollinators for the biofuel plant Jatropha curcas (L.) in a site of tropical southeastern Mexico, within its center of origin. The plants were monoecious with inflorescences of unisexual flowers. The male flowers produced from 3062–5016 pollen grains (266–647 per anther). The plants produced fruits with both geitonogamy and xenogamy, although insect pollination significantly increased the number and quality of fruits. A high diversity of flower visiting insects (36 species) was found, of which nine were classified as efficient pollinators. The native stingless bees Scaptotrigona mexicana (Guérin-Meneville) and Trigona (Tetragonisca) angustula (Latreille) were the most frequent visitors and their presence coincided with the hours when the stigma was receptive. It is noteworthy that the female flowers open before the male flowers, favoring xenogamy, which may explain the high genetic variability reported in J. curcas for this region of the world. PMID:26989640

  4. User-centered design and interactive health technologies for patients.

    PubMed

    De Vito Dabbs, Annette; Myers, Brad A; Mc Curry, Kenneth R; Dunbar-Jacob, Jacqueline; Hawkins, Robert P; Begey, Alex; Dew, Mary Amanda

    2009-01-01

    Despite recommendations that patients be involved in the design and testing of health technologies, few reports describe how to involve patients in systematic and meaningful ways to ensure that applications are customized to meet their needs. User-centered design is an approach that involves end users throughout the development process so that technologies support tasks, are easy to operate, and are of value to users. In this article, we provide an overview of user-centered design and use the development of Pocket Personal Assistant for Tracking Health (Pocket PATH) to illustrate how these principles and techniques were applied to involve patients in the development of this interactive health technology. Involving patient-users in the design and testing ensured functionality and usability, therefore increasing the likelihood of promoting the intended health outcomes.

  5. Spatial Information Technology Center at Fulton-Montgomery Community College

    NASA Technical Reports Server (NTRS)

    2004-01-01

    The Spatial Information Technology Center (SITC) at Fulton-Montgomery Community College (FMCC) continued to fulfill its mission and charter by successfully completing its fourth year of operations under Congressional funding and NASA sponsorship. Fourth year operations (01 Oct 03 - 30 Sep 04) have been funded and conducted utilizing an authorized Research Grant NAG 13-02053 (via a one-year no-cost extension expiring Sep 04). Drawdown and reporting of fiscal activities for SITC operations passes through the Institute for the Application of Geo-spatial Technology (IAGT) at Cayuga Community College in Auburn, New York. Fiscal activity of the Center is reported quarterly via SF 272 to IAGT, this report contains an overview and expenditures for the remaining funds of NAG 13-02053. NAG 13-02053, slated for operating costs for the fiscal year FY02-03, received a one-year no-cost extension. SITC also received permission to use remaining funds for salaries and benefits through December 31,2004. The IAGT receives no compensation for administrative costs. This report includes addendums for the NAG award as required by federal guidelines. Attached are the signed Report of New Technology/Inventions and a Final Property Report. As an academic, economic, and workforce development program, the Center has made significant strides in bringing the technology, knowledge and applications of the spatial information technology field to the region it serves. Through the mission of the Center, the region's communities have become increasingly aware of the benefits of Geospatial technology, particularly in the region s K-12 arena. SITC continues to positively affect the region's education, employment and economic development, while expanding its services and operations.

  6. Mid-Atlantic Technology Applications Center. Quarters 1-4

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Mid-atlantic Technology Application Center (MTAC) pursued a number of initiatives designed to enhance the strategic position of the Langley Research Center (LaRC) and NASA in industry. Among these was a closer association with the ISA, International Society for Measurement and Control. During 1997, MTAC placed articles regarding NASA-developed technologies in each In Tech magazine. The monthly magazine is sent to 46,000 sensors and instrumentation professionals. In addition, MTAC coordinated NASXs participation in the ISA Tech 97 Conference, securing $112,000 of free exhibit space, 1500 NASA sensors posters at no cost to NASA, and thousands of dollars of free publicity. MTAC was awarded a contract by ISA to operate its Technical Resource Center (TRC). The goal of this project is to determine what user needs are in order to identify opportunities for collaboration between NASA centers and companies. In addition, the TRC work will lay the groundwork for the Technology Development Consortium (TDC) proposed by MTAC. The purpose of the TDC is to: match current industry needs with NASA technologies available now, and to identify future needs of NASA and industry which may lead to dual use projects. The goal of these activities is twofold: to infuse NASA technologies into the sensors and instrumentation industry and to secure industry funds to support NASA technology development projects. The instrumentation and sensors industry is valued at $30 billion worldwide, with $12 billion in sales in the United States. The growth rate averages 13.5%, so that by the year 2000, the industry will produce products worth $49 billion. More than 80% of instruments, sensors and control systems are currently manufactured in the United States. NASA and the industry do not have a history of collaborative projects; MTAC's initiatives in this area are designed to foster working relationships between the two parties that will help maintain U.S. leadership in this field. Mid-atlantic Technology

  7. Incorporation of genetic technologies associated with applied reproductive technologies to enhance world food production.

    PubMed

    Cushman, Robert A; McDaneld, Tara G; Kuehn, Larry A; Snelling, Warren M; Nonneman, Dan

    2014-01-01

    Animal breeding and reproductive physiology have been closely related throughout the history of animal production science. Artificial insemination provides the best method of increasing the influence of sires with superior genetics to improve production traits. Multiple ovulation embryo transfer (MOET) provides some ability to increase the genetic influence of the maternal line as well. The addition of genetic technologies to this paradigm allows for improved methods of selecting sires and dams carrying the best genes for production and yield of edible products and resistance to diseases and parasites. However, decreasing the number of influential parents within a population also increases the risk of propagating a recessive gene that could negatively impact the species (Reprod Domest Anim 44:792-796, 2009; BMC Genomics 11:337, 2010). Furthermore, antagonistic genotypic relationships between production traits and fertility (Anim Prod Sci 49:399-412, 2009; Anim Genet 43:442-446, 2012) suggest that care must be taken to ensure that increasing the frequency of genes with a positive influence on production does not negatively impact the fertility of the replacement females entering the herd.

  8. Socializing the public: invoking Hannah Arendt's critique of modernity to evaluate reproductive technologies.

    PubMed

    Sperling, Daniel

    2012-02-01

    The article examines the writings of one of the most influential political philosophers, Hannah Arendt, and specifically focuses on her views regarding the distinction between the private and the public and the transformation of the public to the social by modernity. Arendt's theory of human activity and critique of modernity are explored to critically evaluate the social contributions and implications of reproductive technologies especially where the use of such technologies is most dominant within Western societies. Focusing on empirical studies on new reproductive technologies in Israel, it is argued, powerfully demonstrates Arendt's theory, and broadens the perspectives through which society should evaluate these new technologies towards a more reflective understanding of its current laws and policies and their affect on women more generally.

  9. Examining Differences in Psychological Adjustment Problems among Children Conceived by Assisted Reproductive Technologies

    ERIC Educational Resources Information Center

    Shelton, Katherine H.; Boivin, Jacky; Hay, Dale; van den Bree, Marianne B. M.; Rice, Frances J.; Harold, Gordon T.; Thapar, Anita

    2009-01-01

    The aim of this study was to examine whether there was variation in levels of psychological adjustment among children conceived through Assisted Reproductive Technologies using the parents' gametes (homologous), sperm donation, egg donation, embryo donation and surrogacy. Information was provided by parents about the psychological functioning of…

  10. Gender, body, biomedicine: how some feminist concerns dragged reproduction to the center of social theory.

    PubMed

    Rapp, R

    2001-12-01

    This article tracks the growth of medical anthropology in the United States in the decades since the 1970s, as it has intersected the expansion of feminist activism and scholarship. I argue that feminist attention to embodied inequalities quickly focused on reproduction as a site of investigation and intervention. Medical anthropology has benefited from feminist concern with stratified reproduction, especially its interrogation of nonnormative and stigmatized fertility and childbearing. When reproduction becomes problematic, it provides a lens through which cultural norms, struggles, and transformations can be viewed. Examples drawn from prenatal diagnosis are particularly revelatory of the diverse interests and stakes we all hold in reproduction.

  11. The koala (Phascolarctos cinereus): a case study in the development of reproductive technology in a marsupial.

    PubMed

    Johnston, Stephen D; Holt, William V

    2014-01-01

    The successful development and application of an assisted breeding program in any animal relies primarily on a thorough understanding of the fundamental reproductive biology (anatomy, physiology and behaviour) of the species in question. Surely, the ultimate goal and greatest hallmark of such a program is the efficacious establishment of a series of reliable techniques that facilitate the reproductive and genetic management of fragmented populations, both in captivity and in the wild. Such an achievement is all the more challenging when the reproductive biology of that species is essentially rudimentary and without adequate reproductive models to compare to. Using the koala (Phascolarctos cinereus) as a case study, this chapter provides some personal insights into the evolution of a concept that began as a small undergraduate student project but that subsequently evolved into the first-ever successful artificial insemination of a marsupial. Apart from this historical perspective, we also provide a brief review of the current reproductive biology of the koala, discuss technical elements of current assisted breeding technology of this species, its potential application to the wombat, and the future role it might play in helping to conserve wild koala populations. There is little doubt that the unique reproductive biology and tractability of the koala has in this case been a benefit rather than a hindrance to the success of artificial breeding in this species.

  12. Wombat reproduction (Marsupialia; Vombatidae): an update and future directions for the development of artificial breeding technology.

    PubMed

    Hogan, Lindsay A; Janssen, Tina; Johnston, Stephen D

    2013-06-01

    This review provides an update on what is currently known about wombat reproductive biology and reports on attempts made to manipulate and/or enhance wombat reproduction as part of the development of artificial reproductive technology (ART) in this taxon. Over the last decade, the logistical difficulties associated with monitoring a nocturnal and semi-fossorial species have largely been overcome, enabling new features of wombat physiology and behaviour to be elucidated. Despite this progress, captive propagation rates are still poor and there are areas of wombat reproductive biology that still require attention, e.g. further characterisation of the oestrous cycle and oestrus. Numerous advances in the use of ART have also been recently developed in the Vombatidae but despite this research, practical methods of manipulating wombat reproduction for the purposes of obtaining research material or for artificial breeding are not yet available. Improvement of the propagation, genetic diversity and management of wombat populations requires a thorough understanding of Vombatidae reproduction. While semen collection and cryopreservation in wombats is fairly straightforward there is currently an inability to detect, induce or synchronise oestrus/ovulation and this is an impeding progress in the development of artificial insemination in this taxon.

  13. Research and technology at the Lyndon B. Johnson Space Center

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Johnson Space Center accomplishments in new and advanced concepts during 1983 are highlighted. Included are research funded by the Office of Aeronautics and Space Technology; Advanced Programs tasks funded by the Office of Space Flight; and Solar System Explorations, Life Sciences, and Earth Sciences and Applications research funded by the Office of Space Sciences and Applications. Summary sections describing the role of the Johnson Space Center in each program are followed by one-page descriptions of significant projects. Descriptions are suitable for external consumption, free of technical jargon, and illustrated to increase ease of comprehension.

  14. Research and technology of the Lyndon B. Johnson Space Center

    NASA Technical Reports Server (NTRS)

    1988-01-01

    Johnson Space Center accomplishments in new and advanced concepts during 1987 are highlighted. Included are research projects funded by the Office of Aeronautics and Space Technology, Solar System Exploration and Life Sciences research funded by the Office of Space Sciences and Applications, and advanced Programs tasks funded by the Office of Space Flight. Summary sections describing the role of the Johnson Space Center in each program are followed by descriptions of significant projects. Descriptions are suitable for external consumption, free of technical jargon, and illustrated to increase ease of comprehension.

  15. Research and technology, Lyndon B. Johnson Space Center

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Johnson Space Center accomplishments in new and advanced concepts during 1984 are highlighted. Included are research funded by the Office of Aeronautics and Space Technology; Advanced Programs tasks funded by the Office of Space Flight; and Solar System Exploration and Life Sciences research funded by the Office of Space Sciences and Applications. Summary sections describing the role of the Johnson Space Center in each program are followed by one page descriptions of significant projects. Descriptions are suitable for external consumption, free of technical jargon, and illustrated to increase ease of comprehension.

  16. DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids

    PubMed Central

    Canovas, Sebastian; Ivanova, Elena; Romar, Raquel; García-Martínez, Soledad; Soriano-Úbeda, Cristina; García-Vázquez, Francisco A; Saadeh, Heba; Andrews, Simon; Kelsey, Gavin; Coy, Pilar

    2017-01-01

    The number of children born since the origin of Assisted Reproductive Technologies (ART) exceeds 5 million. The majority seem healthy, but a higher frequency of defects has been reported among ART-conceived infants, suggesting an epigenetic cost. We report the first whole-genome DNA methylation datasets from single pig blastocysts showing differences between in vivo and in vitro produced embryos. Blastocysts were produced in vitro either without (C-IVF) or in the presence of natural reproductive fluids (Natur-IVF). Natur-IVF embryos were of higher quality than C-IVF in terms of cell number and hatching ability. RNA-Seq and DNA methylation analyses showed that Natur-IVF embryos have expression and methylation patterns closer to in vivo blastocysts. Genes involved in reprogramming, imprinting and development were affected by culture, with fewer aberrations in Natur-IVF embryos. Methylation analysis detected methylated changes in C-IVF, but not in Natur-IVF, at genes whose methylation could be critical, such as IGF2R and NNAT. DOI: http://dx.doi.org/10.7554/eLife.23670.001 PMID:28134613

  17. DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids.

    PubMed

    Canovas, Sebastian; Ivanova, Elena; Romar, Raquel; García-Martínez, Soledad; Soriano-Úbeda, Cristina; García-Vázquez, Francisco A; Saadeh, Heba; Andrews, Simon; Kelsey, Gavin; Coy, Pilar

    2017-02-01

    The number of children born since the origin of Assisted Reproductive Technologies (ART) exceeds 5 million. The majority seem healthy, but a higher frequency of defects has been reported among ART-conceived infants, suggesting an epigenetic cost. We report the first whole-genome DNA methylation datasets from single pig blastocysts showing differences between in vivo and in vitro produced embryos. Blastocysts were produced in vitro either without (C-IVF) or in the presence of natural reproductive fluids (Natur-IVF). Natur-IVF embryos were of higher quality than C-IVF in terms of cell number and hatching ability. RNA-Seq and DNA methylation analyses showed that Natur-IVF embryos have expression and methylation patterns closer to in vivo blastocysts. Genes involved in reprogramming, imprinting and development were affected by culture, with fewer aberrations in Natur-IVF embryos. Methylation analysis detected methylated changes in C-IVF, but not in Natur-IVF, at genes whose methylation could be critical, such as IGF2R and NNAT.

  18. Savannah River Technology Center. Monthly report, May 1993

    SciTech Connect

    Not Available

    1993-05-01

    This report covers the progress and accomplishments made at the Savannah River Technology Center for the month of May 1993. Progress is reported for projects in the following areas: reactors, tritium, separations, environmental, waste management, and general. General projects are: an eight week tutorial of the Los Alamos National Laboratory developed Monte Carlo Neutron Photon (MCNP) code; development of materials and fabrication technologies for the spallation and tritium targets for the accelerator production of tritium; and a program to develop welding methods to repair stainless steel containing helium.

  19. NASA Stennis Space Center Test Technology Branch Activities

    NASA Technical Reports Server (NTRS)

    Solano, Wanda M.

    2000-01-01

    This paper provides a short history of NASA Stennis Space Center's Test Technology Laboratory and briefly describes the variety of engine test technology activities and developmental project initiatives. Theoretical rocket exhaust plume modeling, acoustic monitoring and analysis, hand held fire imaging, heat flux radiometry, thermal imaging and exhaust plume spectroscopy are all examples of current and past test activities that are briefly described. In addition, recent efforts and visions focused on accomodating second, third, and fourth generation flight vehicle engine test requirements are discussed.

  20. Center for Renewable Energy and Alternative Transportation Technologies (CREATT)

    SciTech Connect

    Mackin, Thomas

    2012-06-30

    The Center for Renewable Energy and Alternative Transportation Technologies (CREATT) was established to advance the state of the art in knowledge and education on critical technologies that support a renewable energy future. Our research and education efforts have focused on alternative energy systems, energy storage systems, and research on battery and hybrid energy storage systems.This report details the Center's progress in the following specific areas: Development of a battery laboratory; Development of a demonstration system for compressed air energy storage; Development of electric propulsion test systems; Battery storage systems; Thermal management of battery packs; and Construction of a micro-grid to support real-world performance monitoring of a renewable energy system.

  1. Accomplishments at NASA Langley Research Center in rotorcraft aerodynamics technology

    NASA Technical Reports Server (NTRS)

    Wilson, John C.

    1988-01-01

    In recent years, the development of aerodynamic technology for rotorcraft has continued successfully at NASA LaRC. Though the NASA Langley Research Center is not the lead NASA center in this area, the activity was continued due to facilities and individual capabilities which are recognized as contributing to helicopter research needs of industry and government. Noteworthy accomplishments which contribute to advancing the state of rotorcraft technology in the areas of rotor design, airfoil research, rotor aerodynamics, and rotor/fuselage interaction aerodynamics are described. Rotor designs were defined for current helicopters and evaluated in wind tunnel testing. These designs have incorporated advanced airfoils defined analytically and also proven in wind tunnel tests. A laser velocimetry system has become a productive tool for experimental definition of rotor inflow/wake and is providing data for rotorcraft aerodynamic code validation.

  2. Technologies for the marketplace from the Centers for Disease Control

    NASA Technical Reports Server (NTRS)

    Reid-Sanden, Frances L.; Greene, R. Eric; Malvitz, Dolores M.

    1991-01-01

    The Centers for Disease Control, a Public Health Service agency, is responsible for the prevention and control of disease and injury. Programs range from surveillance and prevention of chronic and infectious diseases to occupational health and injury control. These programs have produced technologies in a variety of fields, including vaccine development, new methods of disease diagnosis, and new tools to ensure a safer work environment.

  3. Establishment of the Center for Advanced Separation Technologies

    SciTech Connect

    Christopher E. Hull

    2006-09-30

    This Final Technical Report covers the eight sub-projects awarded in the first year and the five projects awarded in the second year of Cooperative Agreement DE-FC26-01NT41091: Establishment of the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  4. Career and Technology Center Honors Julie Hartman | Poster

    Cancer.gov

    By Carolynne Keenan, Contributing Writer On May 7, Julie Hartman was honored by the Frederick County Career and Technology Center (CTC) for her support of the CTC’s Biomedical Sciences Program. As an education program specialist for Outreach and Special Programs at NCI at Frederick, Hartman is responsible for NCI at Frederick’s participation in the program, which is designed to offer Frederick County high school students hands-on, practical laboratory experience beyond the typical classroom setting. 

  5. ESTABLISHMENT OF THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    SciTech Connect

    Hugh W. Rimmer

    2003-07-01

    Technical Progress Report describes progress made on the eight sub-projects awarded in the first year of Cooperative Agreement DE-FC26-01NT41091: Establishment of the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices. Due to the time taken up by the solicitation/selection process, these cover the initial 6-month period of activity only.

  6. A Comparison of Lead Abatement Technologies at Lewis Research Center

    NASA Technical Reports Server (NTRS)

    Jeziorowski, Luz Y.; Calla, Joanne

    1997-01-01

    In 1995, Lewis participated in a pilot test of Lead Specifications. The Specifications were sponsored by the Center to Protect Worker's Rights (CPWR). Entitled "Model Specifications for the Protection of Worker's from Lead on Steel Structures", one aspect of this endeavor was to test and compare several lead abatement technologies. The project overview, objectives, team, and requirements as well as abatement methods and materials are outlined.

  7. Establishment of the Center for Biomedical Technology Innovation

    SciTech Connect

    2001-12-15

    The report discussed the following topics: (1) Orthopedic Devices; (2) Hybrid Vector and Method Resulting in Protein Overproduction by Eukaryotic Cells; (3) Surgical Simulator; (4) CBTI (Center for Biomedical Technology Innovation) as an Incubator for Start-up Companies; (5) Voice-activated, computer-assisted surgical robotics; (6) Through transmission ultrasonic 3-D holography for diagnostic imaging; (7) CBTI's Scibermed{trademark} Virtual Institute (SVI); and (8) Laser Oxygenation Tomography.

  8. Spatial Information Technology Center at Fulton-Montgomery Community College

    NASA Technical Reports Server (NTRS)

    Flinton, Michael E.

    2004-01-01

    The Spatial Information Technology Center (SITC) at Fulton-Montgomery Community College (FMCC) continued to fulfill its mission and charter by successfully completing its third year of operations under Congressional funding and NASA sponsorship. Third year operations (01 Oct 02 - 30 Sep 03) have been funded and conducted utilizing two authorized Research Grants NAG 13-00043 (via a one-year no-cost extension expiring Sep 03) and NAG 13-02053 (one-year no-cost extension expiring Sep 04). Drawdowns and reporting of fiscal activities for SlTC operations continues to pass through the Institute for the Application of Geo-spatial Technology (IAGT) at Cayuga Community College in Auburn, New York. Fiscal activity of the Center is reported quarterly via SF 272 to IAGT, thus this report contains only a budgetary overview and forecast of future expenditures for the remaining funds of NAG 13 - 02053. Funds from NAG 13 - 00043 were exhausted during the fourth quarter of fiscal year FY02 - 03, which necessitated initial draw down of NAG 13 - 02053. The IAGT receives no compensation for administrative costs as authorized and approved by NASA in each award budget. This report also includes the necessary addendums for each NAG award, as required by federal guidelines, though no reportable activities took place within this report period. Attached are the signed Report of New Technology/lnventions and a Final Property Report identifying qualifying equipment purchased by the Center. As an academic, economic and workforce development oriented program, the Center has made significant strides in bringing the technology, knowledge and applications of the spatial information technology field to the region it serves. Through the mission of the Center, the region's educational, economic development and work force communities have become increasingly educated to the benefits of spatial (Geospatial) technology, particularly in the region's K-12 arena. SlTC continues to positively affect the

  9. Center for BioBased Binders and Pollution Reduction Technology

    SciTech Connect

    Thiel, Jerry

    2013-07-01

    Funding will support the continuation of the Center for Advanced Bio-based Binders and Pollution Reduction Technology Center (CABB) in the development of bio-based polymers and emission reduction technologies for the metal casting industry. Since the formation of the center several new polymers based on agricultural materials have been developed. These new materials have show decreases in hazardous air pollutants, phenol and formaldehyde as much as 50 to 80% respectively. The polymers termed bio-polymers show a great potential to utilize current renewable agricultural resources to replace petroleum based products and reduce our dependence on importing of foreign oil. The agricultural technology has shown drastic reductions in the emission of hazardous air pollutants and volatile organic compounds and requires further development to maintain competitive costs and productivity. The project will also research new and improved inorganic binders that promise to eliminate hazardous emissions from foundry casting operations and allow for the beneficial reuse of the materials and avoiding the burdening of overcrowded landfills.

  10. Early embryonic development, assisted reproductive technologies, and pluripotent stem cell biology in domestic mammals.

    PubMed

    Hall, V; Hinrichs, K; Lazzari, G; Betts, D H; Hyttel, P

    2013-08-01

    Over many decades assisted reproductive technologies, including artificial insemination, embryo transfer, in vitro production (IVP) of embryos, cloning by somatic cell nuclear transfer (SCNT), and stem cell culture, have been developed with the aim of refining breeding strategies for improved production and health in animal husbandry. More recently, biomedical applications of these technologies, in particular, SCNT and stem cell culture, have been pursued in domestic mammals in order to create models for human disease and therapy. The following review focuses on presenting important aspects of pre-implantation development in cattle, pigs, horses, and dogs. Biological aspects and impact of assisted reproductive technologies including IVP, SCNT, and culture of pluripotent stem cells are also addressed.

  11. Investigation of Personality Traits between Infertile Women Submitted to Assisted Reproductive Technology or Surrogacy

    PubMed Central

    Asgari, Najmeh; Yazdkhasti, Fariba; Nasr Esfahani, Mohammad Hossein

    2016-01-01

    Background Personality traits affect human relationships, social interactions, treatment procedures, and essentially all human activities. The purpose of this study is to investigate the personality traitsincluding sensation seeking, flexibility, and happiness among a variety of infertile women who were apt to choose assisted reproductive technology (ART) or surrogacy. Materials and Methods This is a cross-sectional study that was performed on 251 infertile women who visited Isfahan and Tehran Reproductive Medicine Center. These fertility clinics are located in Isfahan and Tehran, Iran. In this study, 201 infertile women who underwent treatment using ART and 50 infertile women who tended to have surrogacy were chosen by convenience sampling. Zuckerman’s Sensation Seeking Scale Form V (SSS-V), Psychological Flexibility Questionnaire (adapted from NEO Personality Inventory-Revised) and Oxford Happiness Questionnaire (OHQ) were used as research instruments. All participants had to complete the research instruments in order to be included in this study. Data were analyzed by descriptive-analytical statistics and statistical tests including multivariate analysis of variance (MANOVA) and Z Fisher. Statistically significant effects were accepted for P<0.05. Results In the sensation-seeking variable, there was a meaningful difference between under-study groups. However, the flexibility and happiness variables did not have a significant difference between under-study groups (P<0.001). Interaction between education, employment, and financial status was effective in happiness of infertile women underwent ART (P<0.05), while age, education and financial status were also effective in happiness of infertile women sought surrogacy (P<0.05). A positive meaningful relationship was seen between sensation seeking and flexibility variables in both groups (P<0.05). And a negative meaningful relationship was seen between sensation seeking and happiness in infertile women who sought

  12. The Blue Cross Blue Shield Association Technology Evaluation Center: how we evaluate radiology technologies.

    PubMed

    Ziegler, Kathleen M; Flamm, Carole Redding; Aronson, Naomi

    2005-01-01

    Evidence-based technology assessment can help answer critical questions concerning the safety, effectiveness, and appropriate uses of medical technologies. This practice can be used to avoid the promotion of ineffective technologies and the premature diffusion of technologies that have not been demonstrated to improve patient-oriented health outcomes, both of which draw resources from effective and appropriate medical care. This article describes the process of such evaluation as undertaken by the Blue Cross Blue Shield Association Technology Evaluation Center. The key components of the assessment process are described, including the problem formulation and evaluation of study quality, as well as the process by which the available evidence is judged against the five Technology Evaluation Center criteria.

  13. Incorporation of genetic technologies associated with applied reproductive technologies to enhance world food production

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Animal breeding and reproductive physiology have been closely related throughout the history of animal production science. Artificial insemination provides the best method of increasing the influence of sires with superior genetics to improve production traits. Multiple ovulation embryo transfer (MO...

  14. Distance Learning With NASA Lewis Research Center's Learning Technologies Project

    NASA Technical Reports Server (NTRS)

    Petersen, Ruth

    1998-01-01

    The NASA Lewis Research Center's Learning Technologies Project (LTP) has responded to requests from local school district technology coordinators to provide content for videoconferencing workshops. Over the past year we have offered three teacher professional development workshops that showcase NASA Lewis-developed educational products and NASA educational Internet sites. In order to determine the direction of our involvement with distance learning, the LTP staff conducted a survey of 500 U.S. schools. We received responses from 72 schools that either currently use distance learning or will be using distance learning in 98-99 school year. The results of the survey are summarized in the article. In addition, the article provides information on distance learners, distance learning technologies, and the NASA Lewis LTP videoconferencing workshops. The LTP staff will continue to offer teacher development workshops through videoconferencing during the 98-99 school year. We hope to add workshops on new educational products as they are developed at NASA Lewis.

  15. Impact of swine reproductive technologies on pig and global food production.

    PubMed

    Knox, Robert V

    2014-01-01

    Reproductive technologies have dramatically changed the way pigs are raised for pork production in developed and developing countries. This has involved such areas as pigs produced/sow, more consistent pig flow to market, pig growth rate and feed efficiency, carcass yield and quality, labor efficiency, and pig health. Some reproductive technologies are in widespread use for commercial pork operations [Riesenbeck, Reprod Domest Anim 46:1-3, 2011] while others are in limited use in specific segments of the industry [Knox, Reprod Domest Anim 46:4-6, 2011]. Significant changes in the efficiency of pork production have occurred as a direct result of the use of reproductive technologies that were intended to improve the transfer of genes important for food production [Gerrits et al., Theriogenology 63:283-299, 2005]. While some technologies focused on the efficiency of gene transfer, others addressed fertility and labor issues. Among livestock species, pig reproductive efficiency appears to have achieved exceptionally high rates of performance (PigCHAMP 2011) [Benchmark 2011, Ames, IA, 12-16]. From the maternal side, this includes pigs born per litter, farrowing rate, as well as litters per sow per year. On the male side, boar fertility, sperm production, and sows served per sire have improved as well [Knox et al., Theriogenology, 70:1202-1208, 2008]. These shifts in the efficiency of swine fertility have resulted in the modern pig as one of the most efficient livestock species for global food production. These reproductive changes have predominantly occurred in developed countries, but data suggests transfer and adoption of these in developing countries as well (FAO STAT 2009; FAS 2006) [World pig meat production: food and agriculture organization of the United Nations, 2009; FAS, 2006) Worldwide Pork Production, 2006]. Technological advancements in swine reproduction have had profound effects on industry structure, production, efficiency, quality, and profitability. In

  16. Armstrong Flight Research Center Research Technology and Engineering Report 2015

    NASA Technical Reports Server (NTRS)

    Voracek, David F.

    2016-01-01

    I am honored to endorse the 2015 Neil A. Armstrong Flight Research Center’s Research, Technology, and Engineering Report. The talented researchers, engineers, and scientists at Armstrong are continuing a long, rich legacy of creating innovative approaches to solving some of the difficult problems and challenges facing NASA and the aerospace community.Projects at NASA Armstrong advance technologies that will improve aerodynamic efficiency, increase fuel economy, reduce emissions and aircraft noise, and enable the integration of unmanned aircraft into the national airspace. The work represented in this report highlights the Center’s agility to develop technologies supporting each of NASA’s core missions and, more importantly, technologies that are preparing us for the future of aviation and space exploration.We are excited about our role in NASA’s mission to develop transformative aviation capabilities and open new markets for industry. One of our key strengths is the ability to rapidly move emerging techniques and technologies into flight evaluation so that we can quickly identify their strengths, shortcomings, and potential applications.This report presents a brief summary of the technology work of the Center. It also contains contact information for the associated technologists responsible for the work. Don’t hesitate to contact them for more information or for collaboration ideas.

  17. Publications in academic medical centers: technology-facilitated culture clash.

    PubMed

    Berner, Eta S

    2014-05-01

    Academic culture has a set of norms, expectations, and values that are sometimes tacit and sometimes very explicit. In medical school and other health professions educational settings, probably the most common norm includes placing a high value on peer-reviewed research publications, which are seen as the major evidence of scholarly productivity. Other features of academic culture include encouraging junior faculty and graduate students to share their research results at professional conferences and lecturing with slides as a major way to convey information. Major values that faculty share with journal editors include responsible conduct of research and proper attribution of others' words and ideas. Medical school faculty also value technology and are often quick to embrace technological advances that can assist them in their teaching and research. This article addresses the effects of technology on three aspects of academic culture: education, presentations at professional meetings, and research publications.The technologies discussed include online instruction, dissemination of conference proceedings on the Internet, plagiarism-detection software, and new technologies deployed by the National Center for Biotechnology Information, the home of PubMed. The author describes how the ease of deploying new technologies without faculty changing their norms and behavior in the areas of teaching and research can lead to conflicts of values among key stakeholders in the academic medical community, including faculty, journal editors, and professional associations. The implications of these conflicts and strategies for managing them are discussed.

  18. Robotic Technology Efforts at the NASA/Johnson Space Center

    NASA Technical Reports Server (NTRS)

    Diftler, Ron

    2017-01-01

    The NASA/Johnson Space Center has been developing robotic systems in support of space exploration for more than two decades. The goal of the Center's Robotic Systems Technology Branch is to design and build hardware and software to assist astronauts in performing their mission. These systems include: rovers, humanoid robots, inspection devices and wearable robotics. Inspection systems provide external views of space vehicles to search for surface damage and also maneuver inside restricted areas to verify proper connections. New concepts in human and robotic rovers offer solutions for navigating difficult terrain expected in future planetary missions. An important objective for humanoid robots is to relieve the crew of "dull, dirty or dangerous" tasks allowing them more time to perform their important science and exploration missions. Wearable robotics one of the Center's newest development areas can provide crew with low mass exercise capability and also augment an astronaut's strength while wearing a space suit. This presentation will describe the robotic technology and prototypes developed at the Johnson Space Center that are the basis for future flight systems. An overview of inspection robots will show their operation on the ground and in-orbit. Rovers with independent wheel modules, crab steering, and active suspension are able to climb over large obstacles, and nimbly maneuver around others. Humanoid robots, including the First Humanoid Robot in Space: Robonaut 2, demonstrate capabilities that will lead to robotic caretakers for human habitats in space, and on Mars. The Center's Wearable Robotics Lab supports work in assistive and sensing devices, including exoskeletons, force measuring shoes, and grasp assist gloves.

  19. NASA Johnson Space Center SBIR STTR Program Technology Innovations

    NASA Technical Reports Server (NTRS)

    Krishen, Kumar

    2007-01-01

    The Small Business Innovation Research (SBIR) Program increases opportunities for small businesses to participate in research and development (R&D), increases employment, and improves U.S. competitiveness. Specifically the program stimulates U.S. technological innovation by using small businesses to meet federal R&D needs, increasing private-sector commercialization of innovations derived from federal R&D, and fostering and encouraging the participation of socially disadvantaged businesses. In 2000, the Small Business Technology Transfer (STTR) Program extended and strengthened the SBIR Program, increasing its emphasis on pursuing commercial applications by awarding contracts to small business concerns for cooperative R&D with a nonprofit research institution. Modeled after the SBIR Program, STTR is nevertheless a separately funded activity. Technologies that have resulted from the Johnson Space Center SBIR STTR Program include: a device for regenerating iodinated resin beds; laser-assisted in-situ keratomileusis or LASIK; a miniature physiological monitoring device capable of collecting and analyzing a multitude of real-time signals to transmit medical data from remote locations to medical centers for diagnosis and intervention; a new thermal management system for fibers and fabrics giving rise to new line of garments and thermal-enhancing environments; and a highly electropositive material that attracts and retains electronegative particles in water.

  20. "It just alienated us": a case study to explore the impact of assisted reproductive technology on family relationships.

    PubMed

    Peters, Kathleen; Jackson, Debra; Rudge, Trudy

    2007-01-01

    New reproductive technologies have the capacity to impact on both personal and healthcare relationships. This article utilizes a case study approach to unpack experiences of one couple who encountered immense and unforeseen difficulties as a result of treatment with assisted reproductive technology. Findings of this case reveal both difficulties and breaches in obtaining informed consent and the consequences these breaches have on relationships. Comprehensive information contributes to positive relationships between patients and healthcare providers. Maintaining supportive relationships between all parties concerned with assisted reproductive technology services is essential, as rifts in these relationships can be devastating and long-lasting.

  1. Genetic technologies and the regulation of reproductive decision-making in Australia.

    PubMed

    Karpin, Isabel; Bennett, Belinda

    2006-08-01

    This article provides a critical analysis of the current Australian regulatory landscape at the interface between genetics and reproductive decision-making. The authors argue that a comparative analysis with other countries and international law and a contextual examination of the way law regulates concepts such as disease and health, abnormality and normality is necessary before we can develop appropriate policy and legislative responses in this area. Specific genetic testing technologies are considered including prenatal genetic testing, preimplantation genetic diagnosis and inheritable genetic modification. An increasing number of members of the Australian community are using genetic testing technologies when they decide to have a baby. The authors argue that as concepts of disease and health vary among members of the community and the potential to test for traits other than illness increases, a new tension arises between an ethic of individual choice and a role for government in regulating reproductive decision-making.

  2. Potential Influence of the Microbiome on Infertility and Assisted Reproductive Technology

    PubMed Central

    Sirota, Ido; Zarek, Shvetha M.; Segars, James H.

    2014-01-01

    Although an altered vaginal microbiota has been demonstrated to affect parturition, its role in assisted reproductive technologies is uncertain. Nevertheless, the effect of known pathogens such as Mycoplasma tuberculosis, Chlamydia trachomatis, and Neisseria gonorrhoeae is clear, causing subclinical changes thought to be risk factors in subfertility. The Human Microbiome Project (HMP) has allowed for metagenomic studies to aid in characterizing normal vaginal flora. Recent findings from the HMP demonstrate that many different species of Lactobacillus are present in the vaginal tract, with a few that predominate. Studies that characterize the vaginal microbiome in assisted reproductive technology support the hypothesis that colonizing the transfer-catheter tip with Lactobacillus crispatus at the time of embryo transfer may increase the rates of implantation and live birth rate while decreasing the rate of infection. In addition, there is some evidence that a progesterone-resistant endometrium might increase the risk of an abnormal vaginal microbiome. PMID:24390919

  3. [Preparation for assisted reproductive technology in the course of infertility treatment in the female soldiers].

    PubMed

    Shmidt, A A; Molchanov, O L; Abashin, V G; Yarman, S A; Beskrovnyi, S V

    2016-04-01

    The level of obstetric morbidity in servicewomen remains high. Infertility occurs more often among the families of servicemen, than among the other families. The leading causative factor among the families suffering from infertility is tuboperitoneal or tubal (up to 85%). Assisted reproductive technologies are often the only possible mean to solve the problem of infertility in case of these forms of infertility.. The families of servicemen suffering from infertility were suggested the echelon principle of health care in military-medical institutions of the Ministry of Defence of the Russian Federation. Defined selection rules and directions, requiring the separation of the assisted reproductive technologies Clinic of Obstetrics and Gynaecology of the Kirov Military Medical Academy to carry out in vitro fertilization procedures.

  4. Future Directions in Rotorcraft Technology at Ames Research Center

    NASA Technical Reports Server (NTRS)

    Aiken, Edwin W.; Ormiston, Robert A; Young, Larry A.

    2000-01-01

    Members of the NASA and Army rotorcraft research community at Ames Research Center have developed a vision for 'Vertical Flight 2025'. This paper describes the development of that vision and the steps being taken to implement it. In an effort to realize the vision, consistent with both NASA and Army Aviation strategic plans, two specific technology development projects have been identified: (1) one focused on a personal transportation system capable of vertical flight (the 'Roto-Mobile') and (2) the other on small autonomous rotorcraft (which is inclusive of vehicles which range in grams of gross weight for 'MicroRotorcraft' to thousands of kilograms for rotorcraft uninhabited aerial vehicles). The paper provides a status report on these projects as well as a summary of other revolutionary research thrusts being planned and executed at Ames Research Center.

  5. The 1991 research and technology report, Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Soffen, Gerald (Editor); Ottenstein, Howard (Editor); Montgomery, Harry (Editor); Truszkowski, Walter (Editor); Frost, Kenneth (Editor); Sullivan, Walter (Editor); Boyle, Charles (Editor)

    1991-01-01

    The 1991 Research and Technology Report for Goddard Space Flight Center is presented. Research covered areas such as (1) earth sciences including upper atmosphere, lower atmosphere, oceans, hydrology, and global studies; (2) space sciences including solar studies, planetary studies, Astro-1, gamma ray investigations, and astrophysics; (3) flight projects; (4) engineering including robotics, mechanical engineering, electronics, imaging and optics, thermal and cryogenic studies, and balloons; and (5) ground systems, networks, and communications including data and networks, TDRSS, mission planning and scheduling, and software development and test.

  6. Oklahoma State University proposed Advanced Technology Research Center. Environmental Assessment

    SciTech Connect

    1995-06-01

    The Department of Energy (DOE) has prepared an Environmental Assessment (EA) evaluating the construction and equipping of the proposed Advanced Technology Research Center (ATRC) at Oklahoma State University (OSU) in Stillwater, Oklahoma. Based on the analysis in the EA, the DOE has determined that the proposed action does not constitute a major federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969. Therefore, the preparation of an Environmental Impact Statement is not required.

  7. Impacts of reproductive technologies on beef production in the United States.

    PubMed

    Dahlen, Carl; Larson, Jamie; Lamb, G Cliff

    2014-01-01

    Estimations of world population growth indicate that by the year 2050 we will reach nine billion habitants on earth. These estimates impose a tremendous challenge in the current agricultural systems as food supply will need to increase by 100 % in the next 40 years (Food and Agriculture Organization of the United Nations 2009). Beef will be a primary protein source that will assist in meeting the requirements for a portion of the protein in diets of this expanding global populace. Beef is a high-quality protein that contains all essential amino acids for the human body and also contains additional essential nutrients such as iron, zinc, B vitamins, riboflavin, selenium, choline, and conjugated linoleic acid (CLA). Adopting reproductive technologies at greater rates than currently used is a viable method to dramatically enhance production efficiency of beef cattle enterprises.Artificial insemination (AI), estrous synchronization and fixed-time AI (TAI), semen and embryo cryopreservation, multiple ovulation and embryo transfer (MOET), in vitro fertilization, sex determination of sperm or embryos, and nuclear transfer are technologies that are used to enhance the production efficiency of beef operations. In many cases, the development of these technologies is responsible for significant changes to traditional livestock production practices. However, adoption of these technologies appears to has not grown at the same rate in the United States as other formidable beef producing nations. For example, sales of beef semen for AI increased from 3.3 to 11.9 million units between 1993 and 2011 in Brazil, whereas that in the United States has increased from 2.9 to 3.8 million units during the same period. The significant increases in adoption of reproductive technologies in developing countries is likely as a result of the development of practical estrous synchronization and TAI systems that have allowed beef producers the opportunity to eliminate detection of estrus in their

  8. Assisted reproductive technology and congenital overgrowth: some speculations on a case of Pallister-Killian syndrome.

    PubMed

    Chiurazzi, P; Bajer, J; Tabolacci, E; Pomponi, M G; Lecce, R; Zollino, M; Neri, G

    2004-10-15

    We report on a boy with Pallister-Killian syndrome (PKS) who was conceived by assisted reproductive technology (ART), specifically in vitro fertilization (IVF) with parents' gametes. A prenatal diagnosis performed elsewhere by CVS failed to detect the presence of the isochromosome 12p that was demonstrated postnatally in approximately 50% of cultured skin fibroblasts. Given that the patient did not show the congenital overgrowth typical of PKS, we speculate that ART might have restricted overgrowth in this particular case. More broadly, we hypothesize that overgrowth might protect from early demise fetuses conceived by ART, a technology known to cause low and very low birth weight.

  9. The Savannah River Technology Center environmental monitoring field test platform

    SciTech Connect

    Rossabi, J.

    1993-03-05

    Nearly all industrial facilities have been responsible for introducing synthetic chemicals into the environment. The Savannah River Site is no exception. Several areas at the site have been contaminated by chlorinated volatile organic chemicals. Because of the persistence and refractory nature of these contaminants, a complete clean up of the site will take many years. A major focus of the mission of the Environmental Sciences Section of the Savannah River Technology Center is to develop better, faster, and less expensive methods for characterizing, monitoring, and remediating the subsurface. These new methods can then be applied directly at the Savannah River Site and at other contaminated areas in the United States and throughout the world. The Environmental Sciences Section has hosted field testing of many different monitoring technologies over the past two years primarily as a result of the Integrated Demonstration Program sponsored by the Department of Energy`s Office of Technology Development. This paper provides an overview of some of the technologies that have been demonstrated at the site and briefly discusses the applicability of these techniques.

  10. The Goddard Space Flight Center (GSFC) robotics technology testbed

    NASA Technical Reports Server (NTRS)

    Schnurr, Rick; Obrien, Maureen; Cofer, Sue

    1989-01-01

    Much of the technology planned for use in NASA's Flight Telerobotic Servicer (FTS) and the Demonstration Test Flight (DTF) is relatively new and untested. To provide the answers needed to design safe, reliable, and fully functional robotics for flight, NASA/GSFC is developing a robotics technology testbed for research of issues such as zero-g robot control, dual arm teleoperation, simulations, and hierarchical control using a high level programming language. The testbed will be used to investigate these high risk technologies required for the FTS and DTF projects. The robotics technology testbed is centered around the dual arm teleoperation of a pair of 7 degree-of-freedom (DOF) manipulators, each with their own 6-DOF mini-master hand controllers. Several levels of safety are implemented using the control processor, a separate watchdog computer, and other low level features. High speed input/output ports allow the control processor to interface to a simulation workstation: all or part of the testbed hardware can be used in real time dynamic simulation of the testbed operations, allowing a quick and safe means for testing new control strategies. The NASA/National Bureau of Standards Standard Reference Model for Telerobot Control System Architecture (NASREM) hierarchical control scheme, is being used as the reference standard for system design. All software developed for the testbed, excluding some of simulation workstation software, is being developed in Ada. The testbed is being developed in phases. The first phase, which is nearing completion, and highlights future developments is described.

  11. National Wind Technology Center sitewide, Golden, CO: Environmental assessment

    SciTech Connect

    1996-11-01

    The National Renewable Energy Laboratory (NREL), the nation`s primary solar and renewable energy research laboratory, proposes to expand its wind technology research and development program activities at its National Wind Technology Center (NWTC) near Golden, Colorado. NWTC is an existing wind energy research facility operated by NREL for the US Department of Energy (DOE). Proposed activities include the construction and reuse of buildings and facilities, installation of up to 20 wind turbine test sites, improvements in infrastructure, and subsequent research activities, technology testing, and site operations. In addition to wind turbine test activities, NWTC may be used to support other NREL program activities and small-scale demonstration projects. This document assesses potential consequences to resources within the physical, biological, and human environment, including potential impacts to: air quality, geology and soils, water resources, biological resources, cultural and historic resources, socioeconomic resources, land use, visual resources, noise environment, hazardous materials and waste management, and health and safety conditions. Comment letters were received from several agencies in response to the scoping and predecisional draft reviews. The comments have been incorporated as appropriate into the document with full text of the letters contained in the Appendices. Additionally, information from the Rocky Flats Environmental Technology Site on going sitewide assessment of potential environmental impacts has been reviewed and discussed by representatives of both parties and incorporated into the document as appropriate.

  12. Center for development technology and program in technology and human affairs. [emphasizing technology-based networks

    NASA Technical Reports Server (NTRS)

    Wong, M. D.

    1974-01-01

    The role of technology in nontraditional higher education with particular emphasis on technology-based networks is analyzed nontraditional programs, institutions, and consortia are briefly reviewed. Nontraditional programs which utilize technology are studied. Technology-based networks are surveyed and analyzed with regard to kinds of students, learning locations, technology utilization, interinstitutional relationships, cost aspects, problems, and future outlook.

  13. Globalisation of birth markets: a case study of assisted reproductive technologies in India

    PubMed Central

    2011-01-01

    The escalation of Assisted Reproductive Technologies (ARTs) in India into a veritable fertility industry is the result of a multitude of reasons. This paper places the bio-genetic industry within the larger political economy framework of globalisation and privatisation, thus employing a framework that is often omitted from discussions on ARTs, but has direct and significant bearings on the ART industry in India. As markets for human organs, tissues and reproductive body parts experience unprecedented growth, the limits of what can or should be bought and sold continue to be pushed. As such, bodies have emerged as sale-worthy economic capital. Commercial flows of reproductive material create and deploy the division of the body into parts over which ownership is claimed, in the process following 'modern routes of capital' and raising issues of structural inequality. This paper presents a brief picture of India's fertility industry with specific focus on its ground-level operation, nature and growth. It aims to explore the industry dimensions of ARTs, by highlighting the macro picture of health care markets and medical tourism in India, the proliferation of the ART industry, market features such as the social imperative to mother, costs, promotion and marketing, unverified claims, inflated success rates, deals and offers, actors and collaborations in the field, and finally, the absence of standards. This paper presents findings from the research 'Constructing Conceptions: The Mapping of Assisted Reproductive Technologies in India', by Sama, a Delhi-based resource group working on gender, health and rights. This research was conducted from 2008 to 2010 in the three states of Uttar Pradesh, Orissa and Tamil Nadu in India, and is one of the first of its kind, highlighting unethical medical practices and making a case for the regulation of the ART industry. As such, it forms a significant part of Sama's ongoing work on women and technologies, particularly policy

  14. Globalisation of birth markets: a case study of assisted reproductive technologies in India.

    PubMed

    Sarojini, Nadimpally; Marwah, Vrinda; Shenoi, Anjali

    2011-08-12

    The escalation of Assisted Reproductive Technologies (ARTs) in India into a veritable fertility industry is the result of a multitude of reasons. This paper places the bio-genetic industry within the larger political economy framework of globalisation and privatisation, thus employing a framework that is often omitted from discussions on ARTs, but has direct and significant bearings on the ART industry in India. As markets for human organs, tissues and reproductive body parts experience unprecedented growth, the limits of what can or should be bought and sold continue to be pushed. As such, bodies have emerged as sale-worthy economic capital. Commercial flows of reproductive material create and deploy the division of the body into parts over which ownership is claimed, in the process following 'modern routes of capital' and raising issues of structural inequality.This paper presents a brief picture of India's fertility industry with specific focus on its ground-level operation, nature and growth. It aims to explore the industry dimensions of ARTs, by highlighting the macro picture of health care markets and medical tourism in India, the proliferation of the ART industry, market features such as the social imperative to mother, costs, promotion and marketing, unverified claims, inflated success rates, deals and offers, actors and collaborations in the field, and finally, the absence of standards. This paper presents findings from the research 'Constructing Conceptions: The Mapping of Assisted Reproductive Technologies in India', by Sama, a Delhi-based resource group working on gender, health and rights. This research was conducted from 2008 to 2010 in the three states of Uttar Pradesh, Orissa and Tamil Nadu in India, and is one of the first of its kind, highlighting unethical medical practices and making a case for the regulation of the ART industry. As such, it forms a significant part of Sama's ongoing work on women and technologies, particularly policy

  15. Scientific and educational center "space systems and technology"

    NASA Astrophysics Data System (ADS)

    Kovalev, I. V.; Loginov, Y. Y.; Zelenkov, P. V.

    2015-10-01

    The issues of engineers training in the aerospace university on the base of Scientific and Educational Center "Space Systems and Technology" are discussed. In order to improve the quality of education in the Siberian State Aerospace University the research work of students, as well as the practice- oriented training of engineers are introduced in the educational process. It was made possible as a result of joint efforts of university with research institutes of the Russian Academy of Science and industrial enterprises. The university experience in this area promotes the development of a new methods and forms of educational activities, including the project-oriented learning technologies, identifying promising areas of specialization and training of highly skilled engineers for aerospace industry and other institutions. It also allows you to coordinate the work of departments and other units of the university to provide the educational process in workshops and departments of the industrial enterprises in accordance with the needs of the target training. Within the framework of scientific and education center the students perform researches, diploma works and master's theses; the postgraduates are trained in advanced scientific and technical areas of enterprise development.

  16. Research and technology, fiscal year 1986, Marshall Space Flight Center

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The Marshall Space Flight Center is continuing its vigorous efforts in space-related research and technology. Extensive activities in advanced studies have led to the approval of the Orbital Maneuvering Vehicle as a new start. Significant progress was made in definition studies of liquid rocket engine systems for future space transportation needs and the conceptualization of advanced laucnch vehicles. The space systems definition studies have brought the Advanced X-ray Astrophysics Facility and Gravity Probe-B to a high degree of maturity. Both are ready for project implementation. Also discussed include significant advances in low gravity sciences, solar terrestrial physics, high energy astrophysics, atmospheric sciences, propulsion systems, and on the critical element of the Space Shuttle Main Engine in particular. The goals of improving the productivity of high-cost repetitive operations on reusable transportation systems, and extending the useful life of such systems are examined. The research and technology highlighted provides a foundation for progress on the Hubble Space Telescope, the Space Station, all elements of the Space Transportation System, and the many other projects assigned to this Center.

  17. Productive Discomfort: Dialogue, Reproductive Choice and Social Justice Education at the Matilda Joslyn Gage Center

    ERIC Educational Resources Information Center

    Roesch Wagner, Sally; Eckler, Tori; Leighton, Maxinne Rhea

    2013-01-01

    Museums in the past have been static institutions, exhibiting their collections as public displays. Today, the public has come to expect more from these institutions, seeing them as safe havens where conversations can begin. As reproductive rights have moved to the forefront of political and social debate, dialogue seems to be a step in the right…

  18. Greenhouse gas (GHG) mitigation technology performance: Activities of the GHG Technology Verification Center. Report for November 1997--September 1998

    SciTech Connect

    Piccot, S.D.; Kirchgessner, D.A.

    1998-12-31

    The paper describes the Greenhouse Gas (GHG) Technology Verification Center`s mission, operational characteristics, and current activities in the natural gas industry, solid waste landfill industry, energy industries, and microelectronics industry. It also outlines the Center`s future plans and gives results of a recent phosphoric acid fuel cell verification at two landflls in the US. It describes how technology vendors, developers, users, and others can utilize the Center`s testing, analysis, and outreach activities and outlines the types of technologies planned for testing over the next 3 to 5 years.

  19. Mars Pathfinder Rover-Lewis Research Center Technology Experiments Program

    NASA Technical Reports Server (NTRS)

    Stevenson, Steven M.

    1997-01-01

    An overview of NASA's Mars Pathfinder Program is given and the development and role of three technology experiments from NASA's Lewis Research Center and carried on the Mars Pathfinder rover is described. Two recent missions to Mars were developed and managed by the Jet Propulsion Laboratory, and launched late last year: Mars Global Surveyor in November 1996 and Mars Pathfinder in December 1996. Mars Global Surveyor is an orbiter which will survey the planet with a number of different instruments, and will arrive in September 1997, and Mars Pathfinder which consists of a lander and a small rover, landing on Mars July 4, 1997. These are the first two missions of the Mars Exploration Program consisting of a ten year series of small robotic martian probes to be launched every 26 months. The Pathfinder rover will perform a number of technology and operational experiments which will provide the engineering information necessary to design and operate more complex, scientifically oriented surface missions involving roving vehicles and other machinery operating in the martian environment. Because of its expertise in space power systems and technologies, space mechanisms and tribology, Lewis Research Center was asked by the Jet Propulsion Laboratory, which is heading the Mars Pathfinder Program, to contribute three experiments concerning the effects of the martian environment on surface solar power systems and the abrasive qualities of the Mars surface material. In addition, rover static charging was investigated and a static discharge system of several fine Tungsten points was developed and fixed to the rover. These experiments and current findings are described herein.

  20. Mars Pathfinder Rover-Lewis Research Center Technology Experiments Program

    NASA Astrophysics Data System (ADS)

    Stevenson, Steven M.

    1997-07-01

    An overview of NASA's Mars Pathfinder Program is given and the development and role of three technology experiments from NASA's Lewis Research Center and carried on the Mars Pathfinder rover is described. Two recent missions to Mars were developed and managed by the Jet Propulsion Laboratory, and launched late last year: Mars Global Surveyor in November 1996 and Mars Pathfinder in December 1996. Mars Global Surveyor is an orbiter which will survey the planet with a number of different instruments, and will arrive in September 1997, and Mars Pathfinder which consists of a lander and a small rover, landing on Mars July 4, 1997. These are the first two missions of the Mars Exploration Program consisting of a ten year series of small robotic martian probes to be launched every 26 months. The Pathfinder rover will perform a number of technology and operational experiments which will provide the engineering information necessary to design and operate more complex, scientifically oriented surface missions involving roving vehicles and other machinery operating in the martian environment. Because of its expertise in space power systems and technologies, space mechanisms and tribology, Lewis Research Center was asked by the Jet Propulsion Laboratory, which is heading the Mars Pathfinder Program, to contribute three experiments concerning the effects of the martian environment on surface solar power systems and the abrasive qualities of the Mars surface material. In addition, rover static charging was investigated and a static discharge system of several fine Tungsten points was developed and fixed to the rover. These experiments and current findings are described herein.

  1. Building Irish families through surrogacy: medical and judicial issues for the advanced reproductive technologies

    PubMed Central

    Sills, Eric Scott; Healy, Clifford M

    2008-01-01

    Surrogacy involves one woman (surrogate mother) carrying a child for another person/s (commissioning person/couple), based on a mutual agreement requiring the child to be handed over to the commissioning person/couple following birth. Reasons for seeking surrogacy include situations where a woman has non-functional or absent reproductive organs, or as a remedy for recurrent pregnancy loss. Additionally, surrogacy may find application in any medical context where pregnancy is contraindicated, or where a couple consisting of two males seek to become parents through oocyte donation. Gestational surrogacy is one of the main issues at the forefront of bioethics and the advanced reproductive technologies, representing an important challenge to medical law. This analysis reviews the history of surrogacy and clinical and legal issues pertaining to this branch of reproductive medicine. Interestingly, the Medical Council of Ireland does not acknowledge surrogacy in its current practice guidelines, nor is there specific legislation addressing surrogacy in Ireland at present. We therefore have developed a contract-based model for surrogacy in which, courts in Ireland may consider when confronted with a surrogacy dispute, and formulated a system to resolve any potential dispute arising from a surrogacy arrangement. While the 2005 report by the Commission on Assisted Human Reproduction (CAHR) is an expert opinion guiding the Oireachtas' development of specific legislation governing assisted human reproduction and surrogacy, our report represents independent scholarship on the contractual elements of surrogacy with particular focus on how Irish courts might decide on surrogacy matters in a modern day Ireland. This joint medico-legal collaborative also reviews the contract for services arrangement between the commissioning person/s and the surrogate, and the extent to which the contract may be enforced. PMID:18983640

  2. The Picatinny Technology Transfer Innovation Center: A business incubator concept adapted to federal laboratory technology transfer

    SciTech Connect

    Wittig, T.; Greenfield, J.

    1996-10-01

    In recent years, the US defense industrial base spawned the aerospace industry, among other successes, and served as the nation`s technology seed bed. However, as the defense industrial base shrinks and public and private resources become scarcer, the merging of the commercial and defense communities becomes necessary to maintain national technological competencies. Cooperative efforts such as technology transfer provide an attractive, cost-effective, well-leveraged alternative to independently funded research and development (R and D). The sharing of knowledge, resources, and innovation among defense contractors and other public sector firms, academia, and other organizations has become exceedingly attractive. Recent legislation involving technology transfer provides for the sharing of federal laboratory resources with the private sector. The Army Research, Development and Engineering Center (ARDEC), Picatinny Arsenal, NJ, a designer of weapons systems, is one of the nation`s major laboratories with this requirement. To achieve its important technology transfer mission, ARDEC reviewed its capabilities, resources, intellectual property, and products with commercial potential. The purpose of the review was to develop a viable plan for effecting a technology transfer cultural change within the ARDEC, Picatinny Arsenal and with the private sector. This report highlights the issues identified, discussed, and resolved prior to the transformation of a temporarily vacant federal building on the Picatinny installation into a business incubator. ARDEC`s discussions and rationale for the decisions and actions that led to the implementation of the Picatinny Technology Transfer Innovation Center are discussed.

  3. Advanced Stirling Technology Development at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Shaltens, Richard K.; Wong, Wayne A.

    2007-01-01

    The NASA Glenn Research Center has been developing advanced energy-conversion technologies for use with both radioisotope power systems and fission surface power systems for many decades. Under NASA's Science Mission Directorate, Planetary Science Theme, Technology Program, Glenn is developing the next generation of advanced Stirling convertors (ASCs) for use in the Department of Energy/Lockheed Martin Advanced Stirling Radioisotope Generator (ASRG). The next-generation power-conversion technologies require high efficiency and high specific power (watts electric per kilogram) to meet future mission requirements to use less of the Department of Energy's plutonium-fueled general-purpose heat source modules and reduce system mass. Important goals include long-life (greater than 14-yr) reliability and scalability so that these systems can be considered for a variety of future applications and missions including outer-planet missions and continual operation on the surface of Mars. This paper provides an update of the history and status of the ASC being developed for Glenn by Sunpower Inc. of Athens, Ohio.

  4. Enhanced Product Generation at NASA Data Centers Through Grid Technology

    NASA Technical Reports Server (NTRS)

    Barkstrom, Bruce R.; Hinke, Thomas H.; Gavali, Shradha; Seufzer, William J.

    2003-01-01

    This paper describes how grid technology can support the ability of NASA data centers to provide customized data products. A combination of grid technology and commodity processors are proposed to provide the bandwidth necessary to perform customized processing of data, with customized data subsetting providing the initial example. This customized subsetting engine can be used to support a new type of subsetting, called phenomena-based subsetting, where data is subsetted based on its association with some phenomena, such as mesoscale convective systems or hurricanes. This concept is expanded to allow the phenomena to be detected in one type of data, with the subsetting requirements transmitted to the subsetting engine to subset a different type of data. The subsetting requirements are generated by a data mining system and transmitted to the subsetter in the form of an XML feature index that describes the spatial and temporal extent of the phenomena. For this work, a grid-based mining system called the Grid Miner is used to identify the phenomena and generate the feature index. This paper discusses the value of grid technology in facilitating the development of a high performance customized product processing and the coupling of a grid mining system to support phenomena-based subsetting.

  5. Female reproductive factors, exogenous hormone use, and pancreatic cancer risk: the Japan Public Health Center-based prospective study.

    PubMed

    Teng, Yvonne; Saito, Eiko; Abe, Sarah K; Sawada, Norie; Iwasaki, Motoki; Yamaji, Taiki; Shimazu, Taichi; Sasazuki, Shizuka; Inoue, Manami; Tsugane, Shoichiro

    2017-03-31

    An association between female reproductive factors, exogenous hormone use, and pancreatic cancer risk has long been suggested in laboratory settings, but epidemiological findings remain mixed and inconclusive. Studies carried out on Asian populations are also limited. In this study, 45 617 women aged 40-69 years were followed for an average of 18.4 years in the Japan Public Health Center-based prospective cohort and 211 pancreatic cases were identified as of 31 December 2011. We applied multivariate-adjusted Cox proportional hazards regression models using age as a time-scale to assess the association between female reproductive factors (menstrual status, menarche age, menopause age, number of births, age at first birth, total years of fertility, history of breastfeeding) and exogenous hormone use with the incidence of pancreatic cancer through hazard ratios and confidence intervals. No significant associations were found between our examined female reproductive factors and pancreatic cancer incidence. The use of exogenous hormones was found to be associated with an increased risk of pancreatic cancer in a multivariate-adjusted model (hazard ratio: 1.47; 95%; confidence interval: 1.00-2.14) in the Japanese female population. Our results suggest that exogenous hormones may play a role in the formation of pancreatic cancer, and further prospective studies are warranted for clarification.

  6. Lab-on-a-chip biophotonics: its application to assisted reproductive technologies.

    PubMed

    Lai, David; Smith, Gary D; Takayama, Shuichi

    2012-08-01

    With the benefits of automation, sensitivity and precision, microfluidics has enabled complex and otherwise tedious experiments. Lately, lab-on-a-chip (LOC) has proven to be a useful tool for enhancing non-invasive assisted reproductive technology (ART). Non-invasive gamete and embryo assessment has largely been through periodic morpohological assessment using optical microscopy and early LOC ART was the same. As we realize that morphological assessment is a poor indication of gamete or embryo health, more advanced biophotonics has emerged in LOC ART to assay for metabolites or gamete separation via optoelectrical tweezers. Off-chip, even more advanced biophotonics with broad spectrum analysis of metabolites and secretomes has been developed that show even higher accuracy to predicting reproductive potential. The integration of broad spectrum metabolite analysis into LOC ART is an exciting future that merges automation and sensitivity with the already highly accurate and strong predictive power of biophotonics.

  7. Beyond conception: legal determinations of filiation in the context of assisted reproductive technologies.

    PubMed

    Mykitiuk, R

    2001-01-01

    This article argues that legal determinations of filiation are normative ideological constructions about how societal relations between parents and children should be ordered. They are based upon regular understandings of the relationship between biological and social facts and, as this article demonstrates, operate to create an asymmetrical relationship between the categories between paternity and maternity. I suggest that fairly recent developments in reproductive and genetic filiation have been made and offer the potential for an expanded understanding of relatedness or kinship which does not take the two-parent--one of each sex--model of the family as its normative form. While the examples I draw on arise in the context of reproductive technologies, I suggest that the analysis has broader implications for the recognition of broader family forms and relationship.

  8. Ethics and new reproductive technologies: an international review of committee statements.

    PubMed

    Walters, LeRoy

    1987-06-01

    Walters examines the statements of advisory committees in eight countries on new practices involving human reproduction: clinical in vitro fertilization; surrogate motherhood; and human embryo research. He analyzes the positions taken by the committees on the general acceptability of the new technologies, as well as on specific issues involved in assisted human reproduction. In chronological order, the statements examined are those of the U.S. Ethics Advisory Board; the Waller committee in Victoria, Australia; a South Australian committee; the Demack committee in Queensland; Britain's Council for Science and Society; Britain's Warnock committee; a Tasmania, Australia, committee; the Ontario Law Reform Commission; Australia's Family Law Council; West Germany's Benda committee; the American Fertility Society; a Western Australia committee; the Dutch Health Council; and the National Ethics Committee of France.

  9. Biodynamic imaging of live porcine oocytes, zygotes and blastocysts for viability assessment in assisted reproductive technologies

    PubMed Central

    An, Ran; Wang, Chunmin; Turek, John; Machaty, Zoltan; Nolte, David D.

    2015-01-01

    The success of assisted reproductive technologies relies on accurate assessment of reproductive viability at successive stages of development for oocytes and embryos. The current scoring system used to select good-quality oocytes relies on morphologically observable traits and hence is indirect and subjective. Biodynamic imaging may provide an objective approach to oocyte and embryo assessment by measuring physiologically-relevant dynamics. Biodynamic imaging is a coherence-gated approach to 3D tissue imaging that uses digital holography to perform low-coherence speckle interferometry to capture dynamic light scattering from intracellular motions. The changes in intracellular activity during cumulus oocyte complex maturation, before and after in vitro fertilization, and the subsequent development of the zygote and blastocyst provide a new approach to the assessment of preimplant candidates. PMID:25798318

  10. Electric Power Research Institute: environmental Control Technology Center.

    SciTech Connect

    1997-09-04

    Operations and maintenance continued this month at the Electric Power Research Institute`s (EPRI`s) Environmental Control Technology Center (ECTC). Testing for the month involved continued investigations into the Clear Liquor Scrubbing Process for the production of Anhydrous Calcium Sulfate (Anhydrite). The 1.0 MW Cold-Side Selective Catalytic Reduction (SCR) unit and the Carbon Injection System (the Pulse-jet Fabric Filter) remained idle this month in a cold-standby mode and were inspected regularly. From May 3-18, the NYSEG Kintigh Station and the ECTC were off-line for a two-week scheduled Station outage. During the ECTC outage, the major systems of the Center were inspected, and several preventive maintenance activities were completed. A listing of the major O&M outage activities completed during this period is presented in the Pilot/Mini-Pilot section of this report. In May 1997, an extension to the Anhydrite Production test block was started following the NYSEG outage. The extension to the Anhydrite Production test block is being funded by the Electric Power Research Institute (EPRI) after promising results from the original test program. Both EPRI and the Department of Energy (DOE) funded the original test program as part of the DOE`s Advanced Power Systems Program, whose mission is to accelerate the commercialization of affordable, high- efficiency, low-emission, coal-fueled electric generating technologies. While the pilot portion of the Anhydrite project was conducted on the 4.0 MW wet FGD pilot unit at EPRI`s Environmental Control Technology Center (ECTC) in Barker, New York, the extension mainly used the 0.4 MW Mini-Pilot wet FGD unit to reduce operating costs. The project is designed to develop an advanced FGD process that produces a useable byproduct, anhydrite (anhydrous calcium sulfate). The original CLS/Anhydrite process included three steps: chloride removal, clear liquor scrubbing, and anhydrite production. The final step in the process involved

  11. Impact of reproductive technologies on dairy food production in the dairy industry.

    PubMed

    Stevenson, Jeffrey S

    2014-01-01

    Reproductive technologies drive the efficiency of managing dairy cows because the lactation cycle of the dairy cow depends on regular calving to renew lactation yields. Achieving timely pregnancies to allow calving every 12-14 months, therefore, is critical in modern dairy production. To meet the demands to produce sufficient milk for fluid and dairy products, various technologies are applied to enhance efficiencies on the dairy farm. Artificial insemination (AI), embryo transfer, ultrasonographic and chemical detection of pregnancy, various monitors that detect or predict estrus, and handheld communication and testing devices allow managers to retrieve information to make cow-side decisions about health and reproductive status. Genomic testing of young potential sires or young heifers is now possible and can provide information about their genetic merit years before any progeny tests can be completed. In many countries, the challenge faced by dairy producers is their ability to afford these technologies in the face of rising feed and labor costs and volatile milk prices received at the farm gate. Government policies often place obstacles, trade barriers, and unfunded mandates that preclude operations from making a modest profit. Unlike nearly all other manufacturing industries, agriculture producers have little control over the price received for their products. Therefore, dairy production is vulnerable to many uncontrolled factors including climate, government policy, economic conditions, and skilled labor shortages. It is clear that the impact of emerging and current reproductive technologies is critical to the management of dairy cattle to produce sufficient milk to meet consumer demands for quality fluid and dairy products.

  12. An Australasian perspective on the role of reproductive technologies in world food production.

    PubMed

    Martin, Graeme B

    2014-01-01

    Industries based on small ruminants are major contributors to world food supply but, in extensive grazing systems, reproductive technology is not directly relevant to most enterprises. More important is the need to respond to demand in high-profit export markets for products that are 'clean, green and ethical' (CGE). This combination of issues led to the concept of CGE management of reproduction that is based on scientific evidence but does not require complex technology. Nutrition is the major challenge because we are limited primarily to the grazing of forages and pastures, but responding to this challenge opens up opportunities-new forages can supply energy and protein whilst improving animal health and welfare, and reducing carbon emissions. A second major factor is the need for accurate coordination of nutritional inputs with reproductive events to ensure that the metabolic signals are appropriate. To control of the timing of reproduction, we need to move beyond simply managing the presence of the male and seek more precision. Our ultimate CGE package is thus based on manipulation of male socio-sexual signals as well as nutrition, in combination with greater use of ultrasound and birth-site management to prevent neonatal mortality. Finally, genetics is critical in the development of the CGE package.It would be difficult to incorporate the entire package in one hit-adaptations are needed to cover variations in genotype and the geographical and socio-economic environment, and some concepts need research and development. Therefore, we have suggested staged introduction of the elements of the package.CGE management can be simple and cost-effective, and improve productivity whilst safeguarding the future of the industries in society and the marketplace. Reproductive technology might not be used by many farmers but it will be an essential tool for realizing the vision because it underpins the acceleration of genetic progress in otherwise tardy grazing industries

  13. Organizational Cultural Assessment of the Energy Technology Engineering Center

    SciTech Connect

    Not Available

    1991-04-01

    An Organizational Cultural Assessment (OCA) was performed at the Energy Technology Engineering Center (ETEC) by administering an Organizational Culture Survey (OCS) that queried employees on the subjects of organizational culture, various aspects of communication, employee commitment to ETEC, work group cohesion, coordination of work, environmental, safety and health concerns, hazardous nature of work, and overall job satisfaction. A description of each of the scales used to assess these subjects is discussed below. The primary purpose of administering the survey was to attempt to measure, in a more quantitative and objective way the notion of organizational culture,'' that is, the values, attitudes, and beliefs of the individuals working within the organization. In particular, those aspects of the working environment which are believed to be important influences on the operations of a facility and on the safety issues relevant to the organization were assessed. This document describes the results of this survey. 9 refs., 22 figs., 7 tabs.

  14. An Organizational Cultural Assessment of the Morgantown Energy Technology Center

    SciTech Connect

    Crouch, D.A.; Haber, S.B.

    1991-06-01

    An Organizational Cultural Assessment (OCA) was performed at the Morgantown Energy Technology Center (METC) by administering an Organizational Culture Survey (OCS) that queried employees on the subjects of organizational culture, various aspects of communications, employee commitment, work group cohesion, coordination of work, environmental, safety, and health concerns, hazardous nature of work, safety and overall job satisfaction. The purpose of the OCS is to measure in a quantitative and objective way the notion of culture;'' that is, the values, attitudes, and beliefs of the individuals working within the organization. In addition, through the OCS, a broad sample of individuals can be reached that would probably not be interviewed or observed during the course of a typical assessment. The OCA also provides a descriptive profile of the organization at one point in time that can then be compared to a profile taken at a different point in time to assess changes in the culture of the organization. 9 refs., 33 figs., 6 tabs.

  15. Organizational Cultural Assessment of the Morgantown Energy Technology Center

    SciTech Connect

    Not Available

    1991-06-01

    An Organizational Cultural Assessment (OCA) was performed at the Morgantown Energy Technology Center (METC) by administering an Organizational Culture Survey (OCS) that queried employees on the subjects of organizational culture, various aspects of communications, employee commitment, work group cohesion, coordination of work, environmental, safety, and health concerns, hazardous nature of work, safety and overall job satisfaction. The purpose of the OCS is to measure in a quantitative and objective way the notion of culture; '' that is, the values, attitudes, and beliefs of the individuals working within the organization. In addition, through the OCS, a broad sample of individuals can be reached that would probably not be interviewed or observed during the course of a typical assessment. The OCA also provides a descriptive profile of the organization at one point in time that can than be compared to a profile taken at a different point in time to assess changes in the culture of the organization. 9 refs., 33 figs., 6 tabs.

  16. An organizational survey of the Pittsburgh Energy Technology Center

    SciTech Connect

    Stock, D.A.; Shurberg, D.A.; Haber, S.B.

    1991-09-01

    An Organizational Survey (OS) was administrated at the Pittsburgh Energy Technology Center (PETC) that queried employees on the subjects of organizational culture, various aspects of communications, employee commitment, work group cohesion, coordination of work, environmental, safety, and health concerns, hazardous nature of work, safety and overall job satisfaction. The purpose of the OS is to measure in a quantitative and objective way the notion of culture''; that is, the values attitudes, and beliefs of the individuals working within the organization. In addition, through the OS, a broad sample of individuals can be reached that would probably not be interviewed or observed during the course of a typical assessment. The OS also provides a descriptive profile of the organization at one point in time that can then be compared to a profile taken at a different point in time to assess changes in the culture of the organization.

  17. An organizational survey of the Pittsburgh Energy Technology Center

    SciTech Connect

    Stock, D.A.; Shurberg, D.A.; Haber, S.B.

    1991-09-01

    An Organizational Survey (OS) was administrated at the Pittsburgh Energy Technology Center (PETC) that queried employees on the subjects of organizational culture, various aspects of communications, employee commitment, work group cohesion, coordination of work, environmental, safety, and health concerns, hazardous nature of work, safety and overall job satisfaction. The purpose of the OS is to measure in a quantitative and objective way the notion of ``culture``; that is, the values attitudes, and beliefs of the individuals working within the organization. In addition, through the OS, a broad sample of individuals can be reached that would probably not be interviewed or observed during the course of a typical assessment. The OS also provides a descriptive profile of the organization at one point in time that can then be compared to a profile taken at a different point in time to assess changes in the culture of the organization.

  18. Space technology test facilities at the NASA Ames Research Center

    NASA Technical Reports Server (NTRS)

    Gross, Anthony R.; Rodrigues, Annette T.

    1990-01-01

    The major space research and technology test facilities at the NASA Ames Research Center are divided into five categories: General Purpose, Life Support, Computer-Based Simulation, High Energy, and the Space Exploraton Test Facilities. The paper discusses selected facilities within each of the five categories and discusses some of the major programs in which these facilities have been involved. Special attention is given to the 20-G Man-Rated Centrifuge, the Human Research Facility, the Plant Crop Growth Facility, the Numerical Aerodynamic Simulation Facility, the Arc-Jet Complex and Hypersonic Test Facility, the Infrared Detector and Cryogenic Test Facility, and the Mars Wind Tunnel. Each facility is described along with its objectives, test parameter ranges, and major current programs and applications.

  19. [Activities of Goddard Earth Sciences and Technology Center, Maryland University

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The Goddard Space Flight Center (GSFC) is recognized as a world leader in the application of remote sensing and modeling aimed at improving knowledge of the Earth system. The Goddard Earth Sciences Directorate plays a central role in NASA's Earth Observing System and the U.S. Global Change Research Program. Goddard Earth Sciences and Technology (GEST) is organized as a cooperative agreement with the GSFC to promote excellence in the Earth sciences, and is a consortium of universities and corporations (University of Maryland Baltimore County, Howard University, Hampton University, Caelum Research Corporation and Northrop Grumman Corporation). The aim of this new program is to attract and introduce promising students in their first or second year of graduate studies to Oceanography and Earth system science career options through hands-on instrumentation research experiences on coastal processes at NASA's Wallops Flight Facility on the Eastern Shore of Virginia.

  20. Center for Technology for Advanced Scientific Component Software (TASCS)

    SciTech Connect

    Damevski, Kostadin

    2009-03-30

    A resounding success of the Scientific Discover through Advanced Computing (SciDAC) program is that high-performance computational science is now universally recognized as a critical aspect of scientific discovery [71], complementing both theoretical and experimental research. As scientific communities prepare to exploit unprecedened computing capabilities of emerging leadership-class machines for multi-model simulations at the extreme scale [72], it is more important than ever to address the technical and social challenges of geographically distributed teams that combine expertise in domain science, applied mathematics, and computer science to build robust and flexible codes that can incorporate changes over time. The Center for Technology for Advanced Scientific Component Software (TASCS) tackles these issues by exploiting component-based software development to facilitate collaborative hig-performance scientific computing.

  1. National Wind Technology Center Dynamic 5-Megawatt Dynamometer

    ScienceCinema

    Felker, Fort

    2016-07-12

    The National Wind Technology Center (NWTC) offers wind industry engineers a unique opportunity to conduct a wide range of tests. Its custom-designed dynamometers can test wind turbine systems from 1 kilowatt (kW) to 5 megawatts (MW). The NWTC's new dynamometer facility simulates operating field conditions to assess the reliability and performance of wind turbine prototypes and commercial machines, thereby reducing deployment time, failures, and maintenance or replacement costs. Funded by the U.S. Department of Energy with American Recovery and Reinvestment Act (ARRA) funds, the 5-MW dynamometer will provide the ability to test wind turbine drivetrains and connect those drivetrains directly to the electricity grid or through a controllable grid interface (CGI). The CGI tests the low-voltage ride-through capability of a drivetrain as well as its response to faults and other abnormal grid conditions.

  2. American Society for Reproductive Medicine/Society for Assisted Reproductive Technology position statement on West Nile virus.

    PubMed

    2006-11-01

    Although there is currently no definitive evidence linking West Nile virus (WNV) transmission with reproductive cells, it is recommended that practitioners defer gamete donors who have confirmed or suspected WNV infections.

  3. The German IVF Register as an Instrument to Document Assisted Reproductive Technologies.

    PubMed

    Kadi, S; Wiesing, U

    2016-06-01

    The German IVF Register (Deutsches IVF-Register [D.I.R]) has been collecting and publishing data on the use of IVF and related methods in Germany since 1982. It is the only institution which provides information for all of Germany on procedures and their success rates. For this reason it plays an important role in the provision of information to the public, to patients, political decision-makers and the scientific community. However, the register does not have the data of all centers offering treatment in Germany nor does it have complete datasets on all reported treatments. The register accepts retrospective data entries, it does not publish the success rates of individual centers and up until 2015 it did not provide a summary of information which was suitable for non-specialists. The D.I.R has been the focus of criticism in the past. Even today, the information it provides to the scientific community, the public, political decision-makers and potential patients on the outcomes of assisted reproduction is insufficient. The documentation of reproductive medicine procedures in other countries is much more meaningful.

  4. The construction of meaning by experts and would-be parents in assisted reproductive technology.

    PubMed

    Silva, Susana; Machado, Helena

    2011-09-01

    This article explores the construction of meaning regarding assisted reproductive technology by legal framers, medical practitioners and would-be parents, through the concept of ecology of knowledge. It is argued that these inter-relationships between experts and lay people can be understood in terms of the formation of a social structure of ecology of knowledge, which depends on local and emotional knowledge co-produced by medical doctors, jurists and lay people in dynamic ways without compromising the autonomy of medical, legal and lay knowledge and skills. The assessment of the benefits and risks of assisted reproductive technology partially represents negotiations of knowledge between these social and professional groups, aiming to reproduce existing relations and practices, particularly the social power of medicine and technology, the dominant perceptions about women's and men's bodies and the geneticisation of genealogy. These negotiations of knowledge generate new rights, new social actors, new scientific fields and new ways of thinking and talking about individual and institutional responsibilities. Ecology of knowledge comes imbued with hope, trust, power, credibility of institutions and moralisation whereby some citizens' rights may be weakened.

  5. Center for Center for Technology for Advanced Scientific Component Software (TASCS)

    SciTech Connect

    Kostadin, Damevski

    2015-01-25

    A resounding success of the Scientific Discovery through Advanced Computing (SciDAC) program is that high-performance computational science is now universally recognized as a critical aspect of scientific discovery [71], complementing both theoretical and experimental research. As scientific communities prepare to exploit unprecedented computing capabilities of emerging leadership-class machines for multi-model simulations at the extreme scale [72], it is more important than ever to address the technical and social challenges of geographically distributed teams that combine expertise in domain science, applied mathematics, and computer science to build robust and flexible codes that can incorporate changes over time. The Center for Technology for Advanced Scientific Component Software (TASCS)1 tackles these these issues by exploiting component-based software development to facilitate collaborative high-performance scientific computing.

  6. Continuous quality improvement and assisted reproductive technology multiple gestations: some progress, some answers, more questions.

    PubMed

    Gibbons, William; Grainger, David; Cedars, Marcelle; Jain, Tarun; Klein, Nancy; Stern, Judy

    2007-08-01

    The past decade has seen a fall in the number of embryos transferred accompanied by a reduction in the rate of higher order multiple pregnancies occurring from U.S. assisted reproductive technology (ART) cycles, which is temporally related to voluntary adherence to embryo transfer guidelines. The twin rate has remained relatively constant. The ability to continue the reduction in multiple pregnancies while maintaining advocacy positions for both patient couples and offspring will best occur with attention to scientific, sociologic, economic, and provider issues.

  7. Lessons learnt from sexual and reproductive health and HIV linkages for multipurpose prevention technology service delivery.

    PubMed

    Lusti-Narasimhan, M; Collins, L; Hopkins, J

    2014-10-01

    Provision of comprehensive sexual and reproductive health (SRH) services that meet the complex and diverse needs of women, in particular, within resource-constrained settings, is often exacerbated by separate and uncoordinated reproductive health (RH) and HIV policies and programmes. A Rapid Assessment Tool for Sexual and Reproductive Health and HIV Linkages was developed to assess bi-directional linkages between SRH and HIV at policy, systems and service delivery levels, as well as to identify gaps and contribute to the development of country-specific action plans. Findings from the implementation of this Assessment Tool are of particular relevance to the successful delivery and uptake of multipurpose prevention technologies (MPTs), which are products in the development pipeline addressing multiple SRH needs of women, including HIV. The findings highlight the need for better coordination between SRH and HIV programmes in countries; support and training for healthcare providers on SRH, HIV and human rights; supporting SRH and HIV integration at the service delivery level through relevant policies, strategic and operational plans; and strengthening logistics and supplies systems to provide a combination approach to prevention. These lessons learnt could help programme managers and service providers to better understand the strategies for positioning multipurpose prevention products in national policy and service contexts.

  8. Fertility tourism: circumventive routes that enable access to reproductive technologies and substances.

    PubMed

    Bergmann, Sven

    2011-01-01

    “Fertility tourism” is a journalistic eye‐catcher focusing on the phenomenon of patients who search for a reproductive treatment in another country in order to circumvent laws, access restrictions, or waiting lists in their home country. In Europe, the reasons why people seek reproductive treatments outside their national boundaries are quite diverse, in part because regulations differ so much among countries. Beginning with four examples of people who crossed borders for an in vitro fertilization (IVF) treatment with gamete donation, this article provides some insight into these transnational circumvention practices based on material from ethnographic fieldwork and interviews in Spain, Denmark, and the Czech Republic. In all three countries, gamete donation is made strictly anonymous. Clinical practices such as egg donor recruitment and phenotypical matching between donors and recipients serve to naturalize the substitution of gametes and to install social legitimacy through resemblance markers with the prospective child. In comparison to other areas of medical tourism, which are subjects of debate as a consequence of neoliberal health politics and international medical competition, mobility in the area of reproductive technologies is deeply intertwined with new forms of doing kinship. For prospective parents, it holds a promise of generating offspring who could pass as biogenetically conceived children. Therefore, IVF with gamete donation is mostly modeled after conceptions of nature. Through anonymity and concealment it creates forms of nonrelatedness that leave space for future imaginings and traces of transnational genetic creators.

  9. Epigenetic disorders and altered gene expression after use of Assisted Reproductive Technologies in domestic cattle.

    PubMed

    Urrego, Rodrigo; Rodriguez-Osorio, Nélida; Niemann, Heiner

    2014-06-01

    The use of Assisted Reproductive Technologies (ARTs) in modern cattle breeding is an important tool for improving the production of dairy and beef cattle. A frequently employed ART in the cattle industry is in vitro production of embryos. However, bovine in vitro produced embryos differ greatly from their in vivo produced counterparts in many facets, including developmental competence. The lower developmental capacity of these embryos could be due to the stress to which the gametes and/or embryos are exposed during in vitro embryo production, specifically ovarian hormonal stimulation, follicular aspiration, oocyte in vitro maturation in hormone supplemented medium, sperm handling, gamete cryopreservation, and culture of embryos. The negative effects of some ARTs on embryo development could, at least partially, be explained by disruption of the physiological epigenetic profile of the gametes and/or embryos. Here, we review the current literature with regard to the putative link between ARTs used in bovine reproduction and epigenetic disorders and changes in the expression profile of embryonic genes. Information on the relationship between reproductive biotechnologies and epigenetic disorders and aberrant gene expression in bovine embryos is limited and novel approaches are needed to explore ways in which ARTs can be improved to avoid epigenetic disorders.

  10. Epigenetic disorders and altered gene expression after use of Assisted Reproductive Technologies in domestic cattle

    PubMed Central

    Urrego, Rodrigo; Rodriguez-Osorio, Nélida; Niemann, Heiner

    2014-01-01

    The use of Assisted Reproductive Technologies (ARTs) in modern cattle breeding is an important tool for improving the production of dairy and beef cattle. A frequently employed ART in the cattle industry is in vitro production of embryos. However, bovine in vitro produced embryos differ greatly from their in vivo produced counterparts in many facets, including developmental competence. The lower developmental capacity of these embryos could be due to the stress to which the gametes and/or embryos are exposed during in vitro embryo production, specifically ovarian hormonal stimulation, follicular aspiration, oocyte in vitro maturation in hormone supplemented medium, sperm handling, gamete cryopreservation, and culture of embryos. The negative effects of some ARTs on embryo development could, at least partially, be explained by disruption of the physiological epigenetic profile of the gametes and/or embryos. Here, we review the current literature with regard to the putative link between ARTs used in bovine reproduction and epigenetic disorders and changes in the expression profile of embryonic genes. Information on the relationship between reproductive biotechnologies and epigenetic disorders and aberrant gene expression in bovine embryos is limited and novel approaches are needed to explore ways in which ARTs can be improved to avoid epigenetic disorders. PMID:24709985

  11. Intelligent Processing Equipment Developments Within the Navy's Manufacturing Technology Centers of Excellence

    NASA Technical Reports Server (NTRS)

    Nanzetta, Philip

    1992-01-01

    The U.S. Navy has had an active Manufacturing Technology (MANTECH) Program aimed at developing advanced production processes and equipment since the late-1960's. During the past decade, however, the resources of the MANTECH program were concentrated in Centers of Excellence. Today, the Navy sponsors four manufacturing technology Centers of Excellence: the Automated Manufacturing Research Facility (AMRF); the Electronics Manufacturing Productivity Facility (EMPF); the National Center for Excellence in Metalworking Technology (NCEMT); and the Center of Excellence for Composites Manufacturing Technology (CECMT). This paper briefly describes each of the centers and summarizes typical Intelligent Equipment Processing (IEP) projects that were undertaken.

  12. The need for interaction between assisted reproduction technology and genetics: recommendations of the European Societies of Human Genetics and Human Reproduction and Embryology.

    PubMed

    2006-08-01

    Infertility and reproductive genetic risk are both increasing in our societies because of lifestyle changes and possibly environmental factors. Owing to the magnitude of the problem, they have implications not only at the individual and family levels but also at the community level. This leads to an increasing demand for access to assisted reproduction technology (ART) and genetic services, especially when the cause of infertility may be genetic in origin. The increasing application of genetics in reproductive medicine and vice versa requires closer collaboration between the two disciplines. ART and genetics are rapidly evolving fields where new technologies are currently introduced without sufficient knowledge of their potential long-term effects. As for any medical procedures, there are possible unexpected effects which need to be envisaged to make sure that the balance between benefits and risks is clearly on the benefit side. The development of ART and genetics as scientific activities is creating an opportunity to understand the early stages of human development, which is leading to new and challenging findings/knowledge. However, there are opinions against investigating the early stages of development in humans who deserve respect and attention. For all these reasons, these two societies, European Society of Human Genetics (ESHG) and European Society of Human Reproduction and Embryology (ESHRE), have joined efforts to explore the issues at stake and to set up recommendations to maximize the benefit for the couples in need and for the community.

  13. Third-party reproduction in the Internet Age: the new, patient-centered landscape.

    PubMed

    Woodward, Julia T

    2015-09-01

    The rise of the Internet Age has brought a host of sweeping changes to the landscape of third-party reproduction. What began as a dyadic relationship between doctor and patient has evolved into a more complex system in which patients are able to access information online from a variety of external sources. Patients often seek to play a more active role in their third-party reproductive care, and the Internet allows them to do so. Further, demand for both medical and psychosocial information about donors and donor-conceived siblings, available online through patient forums and genetic registries, has altered the perception of gamete donation from a one-time event to an ongoing relationship. The advantages and disadvantages for patients and providers of this freer flow of information between third-party participants are examined. Search motivations of recipients and offspring, as well as types of information sought, are detailed. Recommendations are made regarding strategies fertility programs can use to optimally support their patients and navigate this new landscape.

  14. Human Reproduction: Social and Technological Aspects. Innovations: The Social Consequences of Science and Technology Program.

    ERIC Educational Resources Information Center

    McConnell, Mary C.; And Others

    This module is part of an interdisciplinary program designed to educate the general citizenry regarding the issues of science/technology/society that have important consequences for both present and future social policies. Specifically, the program provides an opportunity for students to assess the effects of selected technological innovations in…

  15. Society for assisted reproductive technology position statement on donor suitability of recipients of smallpox vaccine (vaccinia virus).

    PubMed

    2004-09-01

    Although there is presently no definitive evidence linking vaccinia virus transmission through reproductive cells, SART/ASRM accordingly recommends that assisted reproductive technology (ART) practitioners consider deferring donors who have recently received smallpox vaccine or contracted symptomatic vaccinia virus infection through close contact with a vaccine recipient (until after the vaccine or infectious scab has spontaneously separated). Good donor practice further suggests that donors who are not in good health, including those with recent complications from smallpox vaccine, should be similarly deferred.

  16. Society for assisted reproductive technology position statement on donor suitability of recipients of smallpox vaccine (vaccinia virus).

    PubMed

    2004-04-01

    Although there is presently no definitive evidence linking vaccinia virus transmission through reproductive cells, SART/ASRM accordingly recommends that assisted reproductive technology (ART) practitioners consider deferring donors who have recently received smallpox vaccine or contracted symptomatic vaccinia virus infection through close contact with a vaccine recipient (until after the vaccine or infectious scab has spontaneously separated). Good donor practice further suggests that donors who are not in good health, including those with recent complications from smallpox vaccine, should be similarly deferred.

  17. Sperm Encapsulation from 1985 to Date: Technology Evolution and New Challenges in Swine Reproduction.

    PubMed

    Perteghella, S; Vigani, B; Crivelli, B; Spinaci, M; Galeati, G; Bucci, D; Vigo, D; Torre, M L; Chlapanidas, T

    2015-07-01

    In the last 30 years, encapsulation technology has been applied to different species to minimize the loss of spermatozoa after artificial insemination. In particular, the vehiculation of boar sperm cells in barium alginate membrane has proved a valid strategy to reduce the risk of polyspermy and optimize in vivo fertilizing yields. Controlled release of male gametes into the female genital tract has reduced the minimum fertilizing dose of spermatozoa. Notwithstanding these results, encapsulation has not yet reached commercial application, largely due to the additional costs of production. However, encapsulation could be useful in advanced reproductive technology, such as sex sorting, to store sorted boar semen. The controlled release of flow cytometrically sorted spermatozoa could be a promising strategy to reduce the number of cells necessary for each insemination and hence allow the widescale use of sex sorting in this species.

  18. The prospect for international regulatory interventions in embryo transfer and reproductive technologies in the next century.

    PubMed

    Evans, B R

    1999-01-01

    Historically, international regulatory interventions in the area of animal reproductive technologies have focused on the need for mitigation against the dissemination of diseases with the movement of genetics and germplasm across international borders. The continued globalization of agriculture under the Sanitary/Phytosanitary (SPS) Agreement of the World Trade Organization (WTO) ensures that disease considerations arising from third and fourth generation reproductive technologies such as in vitro fertilized embryos, transgenics and xenotransplantation will continue to give rise to animal health regulatory measures. Furthermore, in the aftermath of the raising of the public consciousness and the ensuing consumer confidence crisis concerning animal husbandry and livestock production practices following the Bovine Spongiform Encephalopathy outbreak, evolving societal values are expected to expand regulatory considerations to address veterinary public health and ethical concerns. Consequently, it is expected that the role of the International Embryo Transfer Society in fostering meaningful dialogue and profiling of the research necessary to provide for appropriate science based regulation development will increase in importance.

  19. Application of failure mode and effect analysis in an assisted reproduction technology laboratory.

    PubMed

    Intra, Giulia; Alteri, Alessandra; Corti, Laura; Rabellotti, Elisa; Papaleo, Enrico; Restelli, Liliana; Biondo, Stefania; Garancini, Maria Paola; Candiani, Massimo; Viganò, Paola

    2016-08-01

    Assisted reproduction technology laboratories have a very high degree of complexity. Mismatches of gametes or embryos can occur, with catastrophic consequences for patients. To minimize the risk of error, a multi-institutional working group applied failure mode and effects analysis (FMEA) to each critical activity/step as a method of risk assessment. This analysis led to the identification of the potential failure modes, together with their causes and effects, using the risk priority number (RPN) scoring system. In total, 11 individual steps and 68 different potential failure modes were identified. The highest ranked failure modes, with an RPN score of 25, encompassed 17 failures and pertained to "patient mismatch" and "biological sample mismatch". The maximum reduction in risk, with RPN reduced from 25 to 5, was mostly related to the introduction of witnessing. The critical failure modes in sample processing were improved by 50% in the RPN by focusing on staff training. Three indicators of FMEA success, based on technical skill, competence and traceability, have been evaluated after FMEA implementation. Witnessing by a second human operator should be introduced in the laboratory to avoid sample mix-ups. These findings confirm that FMEA can effectively reduce errors in assisted reproduction technology laboratories.

  20. Health Information Technology Adoption in California Community Health Centers

    PubMed Central

    Kim, Katherine K.; Rudin, Robert S.; Wilson, Machelle D.

    2016-01-01

    Objectives National and state initiatives to spur adoption of electronic health record (EHR) use and health information exchange (HIE) among providers in rural and underserved communities have been in place for 15 years. Our goal was to systematically assess the impact of these initiatives by quantifying the level of adoption and key factors associated with adoption among community health centers (CHCs) in California. Study Design Cross-sectional statewide survey. Methods We conducted a telephone survey of all California primary care CHCs from August to September 2013. Multiple logistic regressions were fit to test for associations between various practice characteristics and adoption of EHRs, Meaningful Use (MU)–certified EHRs, and HIE. For the multivariable model, we included those variables which were significant at the P = .10 level in the univariate tests. Results We received responses from 194 CHCs (73.5% response rate). Adoption of any EHRs (80.3%) and MU–certified EHRs (94.6% of those with an EHR) was very high. Adoption of HIE is substantial (48.7%) and took place within a few years (mean = 2.61 years; SD = 2.01). More than half (54.7%) of CHCs are able to receive data into the EHR, indicating some level of interoperability. Patient engagement capacity is moderate, with 21.6% offering a personal health record, and 55.2% electronic visit summaries. Rural location and belonging to a multi-site clinic organization both increase the odds of adoption of EHRs, HIE, and electronic visit summary, with odds ratios ranging from 0.63 to 3.28 (all P values <.05). Conclusions Greater adoption of health information technology (IT) in rural areas may be the result of both federal and state investments. As CHCs lack access to capital for investments, continued support of technology infrastructure may be needed for them to further leverage health IT to improve healthcare. PMID:26760431

  1. Technology evaluation center assessment synopsis: full-field digital mammography.

    PubMed

    Rothenberg, Barbara M; Ziegler, Kathleen M; Aronson, Naomi

    2006-08-01

    Full-field digital mammography (FFDM) is proposed as an alternative to screen-film mammography (SFM). The ability to separate and optimize the acquisition, storage, and display of images may allow greater visualization of breast cancers at equal or lower radiation doses, especially in younger women and those with denser breasts. This is a synopsis of a systematic review by the Blue Cross Blue Shield Association Technology Evaluation Center. This updated systematic review primarily incorporated the results of the ACR Imaging Network(R) Digital Mammographic Imaging Screening Trial (DMIST), which provided results on 42,760 asymptomatic women who underwent both FFDM and SFM and showed with reasonable certainty that there was no difference in the accuracy of the 2 modalities for asymptomatic women in general, with some advantages of FFDM in certain subgroups. There were no strong, new studies on the use of digital mammography compared with film mammography in a diagnostic population. However, the DMIST results indicated that tumors detected by FFDM, but not by SFM, were likely to be invasive carcinomas or medium-grade to high-grade ductal carcinoma in situ. On the basis of the suppositions that these are the cancers of greatest interest and the ones more likely to be found in a diagnostic population and that the diagnostic population may be younger on average than the screening population, it was concluded that there is sufficient evidence to support the use of FFDM for diagnostic purposes.

  2. Turbine Inflow Characterization at the National Wind Technology Center: Preprint

    SciTech Connect

    Clifton, A.; Schreck, S.; Scott, G.; Kelley, N.; Lundquist, J.

    2012-01-01

    Utility-scale wind turbines operate in dynamic flows that can vary significantly over timescales from less than a second to several years. To better understand the inflow to utility-scale turbines, two inflow towers were installed and commissioned at the National Renewable Energy Laboratory's (NREL) National Wind Technology Center near Boulder, Colorado, in 2011. These towers are 135 m tall and instrumented with a combination of sonic anemometers, cup anemometers, wind vanes, and temperature measurements to characterize the inflow wind speed and direction, turbulence, stability and thermal stratification to two utility-scale turbines. Herein, we present variations in mean and turbulent wind parameters with height, atmospheric stability, and as a function of wind direction that could be important for turbine operation as well as persistence of turbine wakes. Wind speed, turbulence intensity, and dissipation are all factors that affect turbine performance. Our results shown that these all vary with height across the rotor disk, demonstrating the importance of measuring atmospheric conditions that influence wind turbine performance at multiple heights in the rotor disk, rather than relying on extrapolation from lower levels.

  3. Turbine Inflow Characterization at the National Wind Technology Center

    SciTech Connect

    Clifton, A.; Schreck, S.; Scott, G.; Kelley, N.; Lundquist, J. K.

    2012-01-01

    Utility-scale wind turbines operate in dynamic flows that can vary significantly over timescales from less than a second to several years. To better understand the inflow to utility-scale turbines, two inflow towers were installed and commissioned at the National Renewable Energy Laboratory's (NREL) National Wind Technology Center near Boulder, Colorado, in 2011. These towers are 135 m tall and instrumented with a combination of sonic anemometers, cup anemometers, wind vanes, and temperature measurements to characterize the inflow wind speed and direction, turbulence, stability and thermal stratification to two utility-scale turbines. Herein, we present variations in mean and turbulent wind parameters with height, atmospheric stability, and as a function of wind direction that could be important for turbine operation as well as persistence of turbine wakes. Wind speed, turbulence intensity, and dissipation are all factors that affect turbine performance. Our results show that these all vary with height across the rotor disk, demonstrating the importance of measuring atmospheric conditions that influence wind turbine performance at multiple heights in the rotor disk, rather than relying on extrapolation from lower levels.

  4. Environmental Survey preliminary report, Pittsburgh Energy Technology Center, Pittsburgh, Pennsylvania

    SciTech Connect

    Not Available

    1988-09-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the US Department of Energy (DOE) Pittsburgh Energy Technology Center (PETC) conducted December 7--11, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team specialists are outside experts being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with PETC. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at PETC, and interviews with site personnel. The Survey team developed a Sampling and Analysis (S A) Plan to assist in further assessing certain environmental problems identified during its on-site Survey activities at PETC. The S A Plan will be executed by the Oak Ridge National Laboratory (ORNL). When completed, the Plan's results will be incorporated into the PETC Survey findings for inclusion into the Environmental Survey Summary Report. 64 refs., 23 figs., 29 tabs.

  5. Technology utilization in a non-urban region: Further impact and technique of the Technology Use Studies Center

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Updated information is given pertaining to Technology Use Studies Center (TUSC) clients who are those that receive/use information as disseminated by the center. The client information is presented as a continuation of client data as set forth in the center's previous annual report.

  6. Rethinking reproductive "tourism" as reproductive "exile".

    PubMed

    Inhorn, Marcia C; Patrizio, Pasquale

    2009-09-01

    Whereas reproductive "tourism" implies leisure travel, reproductive "exile" bespeaks the numerous difficulties and constraints faced by infertile patients who are "forced" to travel globally for assisted reproduction. Given this reality, it is time to rethink the language of "reproductive tourism," replacing it with more accurate and patient-centered terms.

  7. Optimal utilization of modern reproductive technologies to maximize the gross margin of milk production.

    PubMed

    Heikkilä, A-M; Peippo, J

    2012-06-01

    In this study, a linear programming model was developed to maximize the gross margin of milk production by determining the optimal use of different reproductive technologies in a dairy herd. The model has the potential to vary the use of conventional artificial insemination, insemination with X-sorted sperm, and the use of unselected or sex-selected embryo recovery and transfer. Data from Finnish dairy herd recording systems were used to parameterize the model. This paper presents the results of 6 scenarios for a herd size of 60 dairy cows. In the basic scenario, the optimum economic combination for Finnish conditions was to inseminate 10 heifers and 22 cows with unsorted semen, 8 heifers with X-sorted sperm, and to use 20 cows as embryo donors which was the upper constraint for this technique. The embryo donors were inseminated with conventional semen for both embryo production and their subsequent pregnancy. Without restriction on embryo recovery, the optimum combination was to use all heifers as donors of sex-selected embryos and all cows as donors of unselected embryos. It was more profitable to produce female embryos with X-sorted sperm than by sorting embryos. Embryo recipients were not economically justified in any scenario. In practice, the optimal strategy is herd-specific depending on the input costs, output values and the technical success of each reproductive technology in that herd. This single-year linear programming model adequately differentiates between breeding technologies within a herd, but further research is needed to develop dynamic models to consider genetic improvement and herd expansion.

  8. Boundaries and risk: Media framing of assisted reproductive technologies and older mothers.

    PubMed

    Campbell, Patricia

    2011-01-01

    Assisted reproductive technologies (ARTs) have historically been sites of heated public controversy. However, with widespread use, the boundary-challenging risks surrounding ARTs have become less newsworthy. One exception includes their use by "older mothers," particularly postmenopausal mothers. In this paper, I review the social science literature related to the risks of ARTs and the conceptualizations of "older mothers". Next, I move to analyze the specific case of 60-year-old Ranjit Hayer, who gave birth to twins in Calgary, Canada, through the context of the Canadian media coverage the week following the birth, using concepts from cultural approaches to risk perception, constructivist studies of technology, and risk communication theory. I argue that risk discourses emerge when technologies and users expose and challenge the contingent stability of the sociotechnical discourses surrounding them. This leads to a public re-opening of a "closed" technology and user and a reconstruction of the risks associated with them. This case demonstrates how an apparently "settled" sociotechnical network becomes reframed in terms of risk, and how the negotiation of this risk reveals, constructs, and interweaves various boundary discourses.

  9. George C. Marshall Space Flight Center Research and Technology Report 2014

    NASA Technical Reports Server (NTRS)

    Keys, A. S. (Compiler); Tinker, M. L. (Compiler); Sivak, A. D. (Compiler)

    2015-01-01

    Many of NASA's missions would not be possible if it were not for the investments made in research advancements and technology development efforts. The technologies developed at Marshall Space Flight Center contribute to NASA's strategic array of missions through technology development and accomplishments. The scientists, researchers, and technologists of Marshall Space Flight Center who are working these enabling technology efforts are facilitating NASA's ability to fulfill the ambitious goals of innovation, exploration, and discovery.

  10. ‘My funky genetics’: BRCA1/2 mutation carriers’ understanding of genetic inheritance and reproductive merger in the context of new repro-genetic technologies

    PubMed Central

    Rubin, Lisa R.; Doyle, Maya; Stern, Rikki; Savin, Katie; Hurley, Karen; Sagi, Michal

    2014-01-01

    INTRODUCTION Deleterious mutations in the BRCA1/BRCA2 genes elevate lifetime risk of breast and ovarian cancer. Each child of a mutation-positive parent has a 50% chance of inheriting it. Pre-implantation genetic diagnosis (PGD) permits prospective parents to avoid transmitting a BRCA1/2 mutation to a child, introducing predictability into a process historically defined by chance. This investigation explored how BRCA1/2 mutation carriers understand genetic inheritance and consider a child’s inheritance of a BRCA1/2 mutation, given the opportunities that exist to pursue PGD. METHOD 39 female and male BRCA1/2 mutation carriers of reproductive age were recruited from urban cancer and reproductive medical centers. Participants completed a standardized educational presentation on PGD and prenatal diagnosis, with pre- and post-test assessments. An interdisciplinary team of qualitative researchers analyzed data using grounded theory techniques. FINDINGS Participants expressed the belief that reproduction yields children with unique genetic strengths and challenges, including the BRCA1/2 mutation, family traits for which predictive tests do not exist, and hypothetical genetic risks. Participants expressed preference for biologically-related children, yet stated their genetically ‘well’ partner’s lineage would be marred through reproductive merger, requiring the well partner to assume the burden of the BRCA1/2 mutation via their children. Participants expressed diverse views of genetically ‘well’ partners’ participation in family planning and risk management decisions. DISCUSSION Pressure to use reprogenetic technology may grow as genetic susceptibility testing becomes more widely available. Work with individuals and couples across the disease spectrum must be attuned to they ways beliefs about genetic inheritance play into reproductive decision making. PMID:22709328

  11. An organizational cultural assessment of the Energy Technology Engineering Center

    SciTech Connect

    Haber, S.B.; Crouch, D.A.

    1991-04-01

    An Organizational Cultural Assessment (OCA) was performed at the Energy Technology Engineering Center (ETEC) by administering an Organizational Culture Survey (OCS) that queried employees on the subjects of organizational culture, various species of communication, employee commitment to ETEC, work group cohesion, coordination of work, environmental, safety and health concerns, hazardous nature of work, and overall job satisfaction. A description of each of the scales used to assess these subjects is discussed. The primary purpose of administering the survey was to attempt to measure, in a more quantitative and objective way the notion of organizational culture, '' that is, the values, attitudes, and beliefs of the individuals working within the organization. In particular, those aspects of the working environment which are believed to be important influences on the operations of a facility and on the safety issues relevant to the organization were assessed. In addition, by conducting a survey, a broad sampling of the individuals in the organization can be obtained. This is especially important when the survey is utilized in conjunction with an assessment or inspection team which typically has only a limited amount of resources to address many issues. The OCS provides a broad, but more comprehensive picture of the organization by querying a much larger number of individuals than could be reached through the assessment team alone. Finally, the OCS provides a descriptive profile of the organization at one point in time. This profile can then can be used as a baseline point against which comparisons of other points in time can be made. Such comparisons may prove valuable and would help to assess changes in the organizational culture. Comparisons of the profiles can also be made across similar facilities. 9 refs., 22 figs., 6 tabs.

  12. The appeal to nature implicit in certain restrictions on public funding for assisted reproductive technology.

    PubMed

    Carter, Drew; Braunack-Mayer, Annette

    2011-10-01

    Certain restrictions on public funding for assisted reproductive technology (ART) are articulated and defended by recourse to a distinction between medical infertility and social infertility. We propose that underlying the prioritization of medical infertility is a vision of medicine whose proper role is to restore but not to improve upon nature. We go on to mark moral responses that speak of investments many continue to make in nature as properly an object of reverence and gratitude and therein (sometimes) a source of moral guidance. We draw on the work of Ludwig Wittgenstein in arguing for the plausibility of an appeal to nature in opposition to the charge that it must contain a logical fallacy. We also invite consideration of the moral plausibility of some appeal to nature. Finally, we examine what follows in the case of ART. Should medicine respect as natural limits that should not be overcome: the need for a man and a woman in reproduction; menopause; and even declining fertility with age? We must first ask ourselves to what degree we should defer to nature in the conduct of medicine, at least in the particular if not the general case. This will involve also asking ourselves what we think is natural and in what instances and spirit might we defy nature. Divergent opinions and policies concerning who should receive ART treatment and public funding are more easily understood in view of the centrality, complexity and fundamental nature of these questions.

  13. A perspective on the impact of reproductive technologies on food production in Africa.

    PubMed

    van Marle-Köster, Esté; Webb, Edward C

    2014-01-01

    Africa for the largest part is still regarded as part of the developing world and has a history of political instability, natural disasters, floods and droughts that all had an effect on the development of livestock production systems and the potential application of biotechnologies. It is expected that the human population in sub Saharan Africa will experience a growth of 1.2 % per year over the next 30 years. There is therefore pressure to increase sustainable productivity of livestock. Reproductive technologies such as Artificial Insemination in Africa were driven primarily by the need to control or prevent venereal diseases like Trichomoniases and Campylobacter fetus in cattle. Reproductive biotechnology had a limited impact in Africa due to several factors including a lack of infrastructure and animal recording systems, clear breeding objectives and continuously changing production systems and markets. Africa has a large variety of genetic resources adapted to the diverse environment and production systems and biotechnology should be applied within this context for an increase in food production.

  14. A review of luteinising hormone and human chorionic gonadotropin when used in assisted reproductive technology.

    PubMed

    Ezcurra, Diego; Humaidan, Peter

    2014-10-03

    Gonadotropins extracted from the urine of post-menopausal women have traditionally been used to stimulate folliculogenesis in the treatment of infertility and in assisted reproductive technology (ART). Products, such as human menopausal gonadotropin (hMG), consist not only of a mixture of the hormones, follicle-stimulating hormone (FSH), luteinising hormone (LH) and human chorionic gonadotropin (hCG), but also other biologically active contaminants, such as growth factors, binding proteins and prion proteins. The actual amount of molecular LH in hMG preparations varies considerably due to the purification process, thus hCG, mimicking LH action, is added to standardise the product. However, unlike LH, hCG plays a different role during the natural human menstrual cycle. It is secreted by the embryo and placenta, and its main role is to support implantation and pregnancy. More recently, recombinant gonadotropins (r-hFSH and r-hLH) have become available for ART therapies. Recombinant LH contains only LH molecules. In the field of reproduction there has been controversy in recent years over whether r-hLH or hCG should be used for ART. This review examines the existing evidence for molecular and functional differences between LH and hCG and assesses the clinical implications of hCG-supplemented urinary therapy compared with recombinant therapies used for ART.

  15. Assisted reproductive technology, epigenetics, and long-term health: a developmental time bomb still ticking.

    PubMed

    Grace, Kristen S; Sinclair, Kevin D

    2009-09-01

    Live birthrates following assisted reproduction account for 1 to 3% of pregnancies in developed countries, and these figures seem set to rise. Concerns regarding the safe use of assisted reproductive technology (ART) for the treatment of infertility have been voiced for several years, yet, to date, the vast majority of children conceived using these techniques are apparently normal. Controversy surrounding reports of epigenetic alterations to genomic imprinting following human ART in recent years has fueled the ongoing debate. In contrast, both the incidence and severity of such anomalies are more apparent following ART in comparative animal species. The reasons for this are not known. By and large, the confounding effects of infertility and advanced maternal age do not apply to animal studies, which report better pregnancy rates following embryo transfer. Perhaps the incidence of imprinting disorders is increased when procedures such as ovarian stimulation, in vitro maturation, or both are used in conjunction with extended periods of embryo culture; this frequently occurs in animal but rarely in human ART. The focus of attention on imprinting, however, may have served to distract the scientific community from more subtle epigenetic modifications to nonimprinted loci in gametes and the preimplantation embryo, with health-related consequences that do not manifest until adulthood. Accumulating evidence from animal studies indicates that such effects, not yet apparent in human subjects, exist; and this may ultimately transpire to be the true developmental legacy of human ART. This article discusses these issues in the context of epigenetic and developmental abnormalities following ART in animals.

  16. Conservation of wild animals by assisted reproduction and molecular marker technology.

    PubMed

    Shivaji, S; Kholkute, S D; Verma, S K; Gaur, Ajay; Umapathy, G; Singh, Anju; Sontakke, Sadanand; Shailaja, K; Reddy, Anuradha; Monika, S; Sivaram, V; Jyotsna, B; Bala, Satyare; Ahmed, M Shakeel; Bala, Aruna; Chandrashekar, B V N; Gupta, Sandeep; Prakash, Surya; Singh, Lalji

    2003-07-01

    Wild animals are an integral component of the ecosystem. Their decimation due to abrupt natural calamities or due to gradual human intervention would be disastrous to the ecosystem and would alter the balance in nature between various biotic components. Such an imbalance could have an adverse effect on the ecosystem. Therefore, there is an urgent need to put an end to the ever increasing list of endangered species by undertaking both in situ and ex situ conservation using tools of modern biology, to ascertain the degree of genetic variation and reproductive competence in these animals. This review highlights the development and use of molecular markers such as microsatellites, minisatellites, mitochondrial control region, cytochrome b and MHC loci to assess the genetic variation in various Indian wild animals such as the lion, tiger, leopard and deer. The review also presents data on the semen profile of the big cats of India. Reproductive technologies such as cryopreservation of semen and artificial insemination in big cats are also highlighted.

  17. Production of reproductively sterile fish: A mini-review of germ cell elimination technologies.

    PubMed

    Wong, Ten-Tsao; Zohar, Yonathan

    2015-09-15

    As seafood consumption shifts from fisheries harvests to artificially propagated aquatic species, the increase of aquaculture activities poses a biological threat to our environment. Selectively bred, non-native and (eventually) genetically engineered farmed fish may escape from aquaculture operations, propagate and/or interbreed with wild stocks and subsequently alter the genetic makeup of populations in the environment. Thus, an effective strategy for bio-containment of farmed fish is critically needed. Farming reproductively sterile fish is the most environmentally sustainable approach to ensure complete bio-containment in large-scale aquaculture operations. Chromosome set manipulations to produce sterile fish, including polyploidy and hybridization, are currently the most common practices in the aquaculture industry. However, they do not always result in 100% sterility of the treated fish. Moreover, triploid fish typically do not perform as well as the non-manipulated diploids under commercial culture conditions. In the last half decade, several genetic engineering methods have been developed to produce sterile fish. In this review, we will address the latest technologies that use transgenic approaches to eliminate germ cells, resulting in the production of sterile fish. These latest advances also led us to the development of egg/embryo immersion methodologies to deliver and screen compounds that can be used to eliminate primordial germ cells and produce sterile fish. This emerging non-transgenic strategy for the production of reproductively sterile fish in aquaculture will also be discussed.

  18. Impact of assisted reproductive technologies: a mitochondrial perspective of cytoplasmic transplantation.

    PubMed

    Harvey, A J; Gibson, T C; Quebedeaux, T M; Brenner, C A

    2007-01-01

    Many of the assisted reproductive techniques associated with maternal aging, disease states, or implantation failure aim to correct poor developmental capacity. These techniques are highly invasive and require the exchange of nuclear or cytoplasmic material from a donor oocyte to compensate for deficiencies inherent in the affected individual. These techniques are based on the assumption that the cytoplasm of the donor oocyte can effectively substitute the necessary component(s) to enable development to proceed. Several studies have attempted to inject cytoplasm from "normal" (young) donors, into aged eggs, again assuming that beneficial components of the cytoplasm are transferred to restore developmental capacity. These invasive assisted reproduction technology (ART) procedures aim to eliminate chromosomal abnormalities, improve the quality of oocytes deficient in some important cytoplasmic factors necessary for maturation and/or subsequent development, and eliminate maternally inherited diseases (particularly mitochondrial myopathies). However, in order to develop such ART, understanding the processes involving mitochondrial DNA replication and transcription is imperative, as asynchrony between mitochondrial and nuclear genomes may cause problems in mitochondrial function, localization, and biogenesis.

  19. The impact of stress and psychosocial interventions on assisted reproductive technology outcome.

    PubMed

    Morreale, Mary; Balon, Richard; Tancer, Manuel; Diamond, Michael

    2011-01-01

    In natural cycles of attempted conception, stress has been shown to predict lower conception rates. The objective of this article is to determine whether stress affects the outcome of assisted reproductive technology (ART) as well. In addition, this article analyzes the effect that psychosocial interventions targeting the reduction of stress have on ART outcomes. This review examined available PubMed articles published in the past 15 years, and 28 articles were included. Looking specifically at numbers of women studied, stress appears to negatively affect ART outcome; interventions targeting stress reduction appear beneficial. Because stress appears to negatively affect ART outcome, and psychosocial interventions do not have detrimental effects, screening for stress should occur and some type of intervention considered during the ART process.

  20. The Italian Constitutional Court modifies Italian legislation on assisted reproduction technology.

    PubMed

    Benagiano, Giuseppe; Gianaroli, Luca

    2010-03-01

    On 8 May 2009, the Italian Constitutional Court declared, at least in part, that the law regulating assisted reproduction technology in Italy (Law 40/04) is unconstitutional. The most important theoretical point made by the Court is that the law does not provide unlimited protection to embryos, since it admits that some of them may not produce a viable fetus. Embryo protection is therefore limited by the imperative to ensure a concrete possibility to achieve a successful pregnancy. The Court also reaffirmed the need to empower the attending physician with the means to carry out a full evaluation. At present, the situation is not clear and, theoretically, requires a new intervention by Parliament. This, however, is unlikely.

  1. Long-term follow-up of children conceived through assisted reproductive technology.

    PubMed

    Lu, Yue-hong; Wang, Ning; Jin, Fan

    2013-05-01

    Children conceived via assisted reproductive technologies (ART) are nowadays a substantial proportion of the population. It is important to follow up these children and evaluate whether they have elevated health risks compared to naturally conceived (NC) children. In recent years there has been a lot of work in this field. This review will summarize what is known about the health of ART-conceived children, encompassing neonatal outcomes, birth defects, growth and gonadal developments, physical health, neurological and neurodevelopmental outcomes, psychosocial developments, risk for cancer, and epigenetic abnormalities. Most of the children conceived after ART are normal. However, there is increasing evidence that ART-conceived children are at higher risk of poor perinatal outcome, birth defects, and epigenetic disorders, and the mechanism(s) leading to these changes have not been elucidated. Continuous follow-up of children after ART is of great importance as they progress through adolescence into adulthood, and new ART techniques are constantly being introduced.

  2. The paternal genome and the health of the assisted reproductive technology child.

    PubMed

    Lewis, Sheena E M; Kumar, Kishlay

    2015-01-01

    As a number of children born by assisted reproductive technology (ART) are increasing each year across the developed world, the health of such offspring is a matter of public concern. Does the integrity of the paternal genome impact on offspring health? In societal terms, as birth rates fall, and the Western population become unsustainable, do the benefits outweigh the costs of creating and providing for this ART conceived subpopulation? There are little data to date to answer these questions. The long-term health of such children has largely been ignored, and success measured only by early (prebirth) outcomes such as embryo quality or pregnancy. However, there are powerful paradigms such as ageing and smoking that give vital clues as to the potential impact of unhealthy spermatozoa on disease risk, mental and physical health, fertility and mortality of these offspring.

  3. Use of microarray technology to profile gene expression patterns important for reproduction in cattle.

    PubMed

    Evans, A C O; Forde, N; O'Gorman, G M; Zielak, A E; Lonergan, P; Fair, T

    2008-07-01

    Fertility in cattle is a major component of many agricultural enterprises and there is pressure to devise methods to improve this. A number of approaches are ongoing, one of which is to better understand the cellular and molecular events of the development of reproductive tissues and to use these as targets for developing new strategies. Microarray technologies now allow us the potential to determine the transcriptional profile of expressed genes in a given tissue. This review focuses on the types of microarrays available for studies in cattle and concludes that genes associated with one or more of the cellular processes of cell survival/death, intracellular signalling, transcription and translation, cell division and proliferation and cellular metabolism are the main transcriptional pathways that control the development of ovarian follicles, oocytes, early embryos and the uterine endometrium about the time of the establishment of pregnancy.

  4. The paternal genome and the health of the assisted reproductive technology child

    PubMed Central

    Lewis, Sheena EM; Kumar, Kishlay

    2015-01-01

    As a number of children born by assisted reproductive technology (ART) are increasing each year across the developed world, the health of such offspring is a matter of public concern. Does the integrity of the paternal genome impact on offspring health? In societal terms, as birth rates fall, and the Western population become unsustainable, do the benefits outweigh the costs of creating and providing for this ART conceived subpopulation? There are little data to date to answer these questions. The long-term health of such children has largely been ignored, and success measured only by early (prebirth) outcomes such as embryo quality or pregnancy. However, there are powerful paradigms such as ageing and smoking that give vital clues as to the potential impact of unhealthy spermatozoa on disease risk, mental and physical health, fertility and mortality of these offspring. PMID:25926606

  5. Assessing Community Informatics: A Review of Methodological Approaches for Evaluating Community Networks and Community Technology Centers.

    ERIC Educational Resources Information Center

    O'Neil, Dara

    2002-01-01

    Analyzes the emerging community informatics evaluation literature to develop an understanding of the indicators used to gauge project impacts in community networks and community technology centers. The study finds that community networks and community technology center assessments fall into five key areas: strong democracy; social capital;…

  6. An Analysis of Collaborative Technology Advancements Achieved through the Center for Network Innovation and Experimentation

    DTIC Science & Technology

    2008-12-01

    COLLABORATIVE TECHNOLOGY ADVANCEMENTS ACHIEVED THROUGH THE CENTER FOR NETWORK INNOVATION AND EXPERIMENTATION by Eric L. Quarles December 2008...Advancements Achieved through the Center for Network Innovation and Experimentation 6. AUTHOR(S) Eric L. Quarles 5. FUNDING NUMBERS 7...cycles which the members of the Naval Postgraduate School Center for Network Innovation and Experimentation (CENETIX) participate. These experiments

  7. Research and technology 1987 annual report of the Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    1987-01-01

    As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, Kennedy Space Center is placing increasing emphasis on the Center's research and technology program. In addition to strengthening those areas of engineering and operations technology that contribute to safer, more efficient, and more economical execution of our current mission, we are developing the technological tools needed to execute the Center's mission relative to future programs. The Engineering Development Directorate encompasses most of the laboratories and other Center resources that are key elements of research and technology program implementation, and is responsible for implementation of the majority of the projects of this Kennedy Space Center 1987 Annual Report.

  8. Natick Soldier Systems Center Science and Technology Board (9th)

    DTIC Science & Technology

    2012-05-29

    Education Program. Peter L. Antoinette President & Chief Executive Officer Nanocomp Technologies, Inc. Peter co-founded Nanocomp Technologies...Inc. in 2004 and serves as its President and Chief Executive Officer. Prior to founding Nanocomp Technologies, he was the President and CEO of

  9. Families Created by the New Reproductive Technologies: Quality of Parenting and Social and Emotional Development of the Children.

    ERIC Educational Resources Information Center

    Golombok, Susan; And Others

    1995-01-01

    Compared family relationships and the social and emotional development of children in families created by new reproductive technologies with those of natural and adoptive families. Found that quality of parenting in experimental families was superior to that of families with a naturally conceived child. No group differences were found for measures…

  10. The Relationship between Selected Educational Technologies and Student-Centered versus Teacher-Centered Instruction

    ERIC Educational Resources Information Center

    Kollmer, Michael J.

    2013-01-01

    Not all teachers and students have equal access to technology. This inequality of access creates an uneven instructional practice that may result in varied student learning. By and large, students have limited access to technology within the confines of the classroom. New educational technologies provide schools with an opportunity to broaden and…

  11. A technology-driven nursing faculty resource center.

    PubMed

    Hasson, Catherine; Cornelius, Fran; Suplee, Patricia Dunphy

    2008-01-01

    With the overwhelming need to recruit and retain more nursing faculty, providing faculty development is imperative. The authors discuss the design, implementation, and evaluation of a virtual Nursing Faculty Resource Center, allowing easy replication in other nursing institutions.

  12. Graduate Automotive Technology Education (GATE) Program: Center of Automotive Technology Excellence in Advanced Hybrid Vehicle Technology at West Virginia University

    SciTech Connect

    Nigle N. Clark

    2006-12-31

    This report summarizes the technical and educational achievements of the Graduate Automotive Technology Education (GATE) Center at West Virginia University (WVU), which was created to emphasize Advanced Hybrid Vehicle Technology. The Center has supported the graduate studies of 17 students in the Department of Mechanical and Aerospace Engineering and the Lane Department of Computer Science and Electrical Engineering. These students have addressed topics such as hybrid modeling, construction of a hybrid sport utility vehicle (in conjunction with the FutureTruck program), a MEMS-based sensor, on-board data acquisition for hybrid design optimization, linear engine design and engine emissions. Courses have been developed in Hybrid Vehicle Design, Mobile Source Powerplants, Advanced Vehicle Propulsion, Power Electronics for Automotive Applications and Sensors for Automotive Applications, and have been responsible for 396 hours of graduate student coursework. The GATE program also enhanced the WVU participation in the U.S. Department of Energy Student Design Competitions, in particular FutureTruck and Challenge X. The GATE support for hybrid vehicle technology enhanced understanding of hybrid vehicle design and testing at WVU and encouraged the development of a research agenda in heavy-duty hybrid vehicles. As a result, WVU has now completed three programs in hybrid transit bus emissions characterization, and WVU faculty are leading the Transportation Research Board effort to define life cycle costs for hybrid transit buses. Research and enrollment records show that approximately 100 graduate students have benefited substantially from the hybrid vehicle GATE program at WVU.

  13. Incidence of abnormal offspring from cloning and other assisted reproductive technologies.

    PubMed

    Hill, Jonathan R

    2014-02-01

    In animals produced by assisted reproductive technologies, two abnormal phenotypes have been characterized. Large offspring syndrome (LOS) occurs in offspring derived from in vitro cultured embryos, and the abnormal clone phenotype includes placental and fetal changes. LOS is readily apparent in ruminants, where a large calf or lamb derived from in vitro embryo production or cloning may weigh up to twice the expected body weight. The incidence of LOS varies widely between species. When similar embryo culture conditions are applied to nonruminant species, LOS either is not as dramatic or may even be unapparent. Coculture with serum and somatic cells was identified in the 1990s as a risk factor for abnormal development of ruminant pregnancies. Animals cloned from somatic cells may display a combination of fetal and placental abnormalities that are manifested at different stages of pregnancy and postnatally. In highly interventional technologies, such as nuclear transfer (cloning), the incidence of abnormal offspring continues to be a limiting factor to broader application of the technique. This review details the breadth of phenotypes found in nonviable pregnancies, together with the phenotypes of animals that survive the transition to extrauterine life. The focus is on animals produced using in vitro embryo culture and nuclear transfer in comparison to naturally occurring phenotypes.

  14. Effect of Antioxidants (β-mercaptoethanol and Cysteamine) on Assisted Reproductive Technology In vitro

    PubMed Central

    Nikseresht, Mohsen; Toori, Mehdi Akbartabar; Rahimi, Hamid Reza; Fallahzadeh, Ali Reza; Kahshani, Iraj Ragerdi; Hashemi, Seyedeh Fatemeh; Bahrami, Solmaz

    2017-01-01

    Introduction Oocyte Culture of Germinal Vesicle (GV) and its growth improves Assisted Reproductive Technology (ART) invitro and infertility. Inappropriate culture medium environment, low quality of oocytes, increase in Oxidative Stress (OS) events, Reactive Oxygen Species (ROS) and free radicals production are the main factors that result in unsuccessful Invitro Maturation (IVM) and decrease in reproduction. Aim The present study was conducted with the aim to evaluate the effect of β-mercaptoethanol (BME) and Cysteamine (CYS) on IVM improvement, embryo fertilization and development of blastocyst of mouse immature oocyte. Materials and Methods Oocytes were obtained from 4-6 weeks old Naval Medical Research Institute (NMRI) female mice, 48 hours after stimulation with Intraperitoneal (IP) injection of 10 IU Pregnant Mare Serum Gonadotropin (PMSG). GV oocyte with and without cumulus cells were isolated from ovaries and cultured in Tissue Culture Medium (TCM) 199 with availability of 100 μM of antioxidants (BME and CYS). After 24 hours, mature oocyte in metaphase II (MII) were fertilized with sperm in In vitro Fertilization (IVF) medium (T6) and evaluated for fetal development into blastocyst. Results BME and CYS could significantly (p<0.05) increase the rate of IVM and oocyte evolution, and embryo formation in medium culture. Furthermore, it is demonstrated that existence of Cumulus Oocyte Complexes (COC) significantly showed better IVM, fertilization and evolution trend as compared to oocytes without cumulus cover or Denuded Oocytes (DO), especially in TCM199 plus BME and CYS. So that the change in GV stage oocytes to MII (maturation rate), fertilization rates or 2PN formation, and two cell embryos formation or blastocyst development rate in the treatment group with addition of BME & CYS and COC was statistically significant as compared to the DO group (p-value < 0.0001). Conclusion Both cellular and environmental factors could be important and involved in ART

  15. NIH Institutes and Centers Served by TTC | NCI Technology Transfer Center | TTC

    Cancer.gov

    TTC services the NCI Intramural Research laboratories as well as nine other NIH institutes a range of services--NIDA, NIA, NIMHD, NICHD, NLM, CIT, NCCIH, Clinical Center, NEI. | [google6f4cd5334ac394ab.html

  16. Museum of Science Builds National Center for Technological Literacy (NCTL)

    ERIC Educational Resources Information Center

    Technology Teacher, 2005

    2005-01-01

    Research indicates that most Americans don't understand the technologies that surround them--the products and systems designed to fill a specific need. From water filtration to wheelchairs, from pens to PDAs, people use technology, often without fully comprehending how these tools are designed, developed, and function. In response, the Museum of…

  17. The Center for Research and Evaluation in the Application of Technology to Education.

    ERIC Educational Resources Information Center

    Rubin, David P.; Weisgerber, Robert A.

    1985-01-01

    The Center for Research and Development in the Application of Technology to Education project identifies effective uses of new technologies for the learning disabled. Areas investigated include effective instructional design principles, program design strategies, adjusting technology for individual learners, software development, and use of…

  18. Just Molly and me, and donor makes three: lesbian motherhood in the age of assisted reproductive technology.

    PubMed

    Ehrensaft, Diane

    2008-01-01

    The psychological experiences of lesbian mothers, both coupled and single, are compared and contrasted with heterosexual and gay parents who use assisted reproductive technology, focusing on issues of parental desire, fertility, babies conceived from science rather than sex, presence of an outside party in conception, genetic asymmetry, social anxieties, legal protections, disclosure, and gender. The psychological meaning of the donor or surrogate as "extra" and "missing" piece of the family, along with the interactive effects of homophobia and "reproductive technophobia" are considered. Lesbian families are recognized to be constructing a new narrative of a bio-social family as they define and live their experience.

  19. Des Moines Energy Center repowering with PCFB technology

    SciTech Connect

    Ambrose, S.J.; Kreumpel, G.E.; Dryden, R.

    1992-01-01

    Iowa Power and Dairyland Power have formed a partnership and entered into an agreement with the United States Department of Energy (DOE) to repower a mothballed electric generating facility using Pressurized Circulating Fluidized Bed (PCFB) combustion technology. The project is the first commercial application of PCFB technology. The project includes the refurbishment of an existing steam turbine cycle, installation of the PCFB and gas turbine, and a two year operating period to demonstrate the technology. The repowered unit is expected to be rated at 80 MW. The plant is scheduled to begin operation in 1996. Process systems are described.

  20. Des Moines Energy Center repowering with PCFB technology

    SciTech Connect

    Ambrose, S.J.; Kreumpel, G.E.; Dryden, R.

    1992-12-01

    Iowa Power and Dairyland Power have formed a partnership and entered into an agreement with the United States Department of Energy (DOE) to repower a mothballed electric generating facility using Pressurized Circulating Fluidized Bed (PCFB) combustion technology. The project is the first commercial application of PCFB technology. The project includes the refurbishment of an existing steam turbine cycle, installation of the PCFB and gas turbine, and a two year operating period to demonstrate the technology. The repowered unit is expected to be rated at 80 MW. The plant is scheduled to begin operation in 1996. Process systems are described.

  1. Severe Maternal Morbidity and the Use of Assisted Reproductive Technology in Massachusetts

    PubMed Central

    Belanoff, Candice; Declercq, Eugene R.; Diop, Hafsatou; Gopal, Daksha; Kotelchuck, Milton; Luke, Barbara; Nguyen, Thien; Stern, Judy E.

    2016-01-01

    Objectives To assess whether risk of severe maternal morbidity at delivery differed for women who conceived using assisted reproductive technology (ART), those with indicators of subfertility but no ART (“subfertile”), and those who had neither ART nor subfertility (“fertile”). Methods This retrospective cohort study was part of the larger Massachusetts Outcomes Study of Assisted Reproductive Technology (MOSART). To construct the MOSART database and identify ART deliveries, we linked ART treatment records to birth certificates and maternal and infant hospitalization records occurring in Massachusetts between 2004 and 2010. An algorithm of ICD-9-CM diagnosis and procedure codes identified severe maternal morbidity. We used Logistic Generalized Estimating Equations to estimate odds of severe maternal morbidity associated with fertility status, adjusting for maternal demographic and health factors and gestational age, stratifying on plurality and method of delivery. Results The prevalence of severe maternal morbidity among this population (n = 458,918) was 1.16%. The overall, crude prevalences of severe maternal morbidity among fertile, subfertile and ART deliveries were 1.09%, 1.44% and 3.14%, respectively. The most common indicator of severe maternal morbidity was blood transfusion. In multivariable analyses, among singletons, ART was associated with increased odds of severe maternal morbidity compared to both fertile (Vaginal: aOR 2.27, 95% CI: 1.78 – 2.88; cesarean: aOR 1.67, 95% CI: 1.40 – 1.98, respectively) and subfertile (vaginal: aOR 1.97, 95% CI: 1.30 – 3.00; cesarean: aOR 1.75, 95% CI: 1.30 – 2.35, respectively) deliveries. Among twins, only cesarean ART deliveries had significantly greater severe maternal morbidity compared to cesarean fertile deliveries (aOR 1.48, 95% CI: 1.14, 1.93). Conclusions Women who conceive through ART may have elevated risk severe maternal morbidity at delivery, largely indicated by blood transfusion, even when

  2. ADVANCED COMPOSITES TECHNOLOGY CASE STUDY AT NASA LANGLEY RESEARCH CENTER

    EPA Science Inventory

    This report summarizes work conducted at the National Aeronautics and Space Administration's Langley Research Center (NASA-LaRC) in Hampton, VA, under the U.S. Environmental Protection Agency’s (EPA) Waste Reduction Evaluations at Federal Sites (WREAFS) Program. Support for...

  3. The College Writing Center: Best Practices, Best Technologies

    ERIC Educational Resources Information Center

    Moberg, Eric

    2010-01-01

    Lifelong learning is a must in our information age, especially in the worldwide recession that began in 2008. In order to gain the most from their education, adult learners in any subject, major, program, or school must master the basics of academic reading and academic writing. Towards this end, writing tutors and writing centers offer…

  4. Results from Organizational Development Interventions in a Technology Call Center.

    ERIC Educational Resources Information Center

    Workman, Michael

    2003-01-01

    Call center staff answered calls in 4 treatments: alignment job design (n=35), autonomous work teams (n=35), high-involvement work processes (n=43), and controls (n=36). Job satisfaction improved in alignment job design and high-involvement treatments, most significantly in the latter. Skill level and attitude toward autonomous work might have…

  5. What Differences Technology Makes for a High School Career Center

    ERIC Educational Resources Information Center

    Haskell, Kathleen Shelton; Haskell, Thomas Owen

    2008-01-01

    Over the last 8 years, the steady integration of new media has facilitated the senior project for College Tech Prep students at the Tri-County Career Center. Through the implementation of a student laptop program, campus-wide Internet access, and the availability of information networks and online research management tools, students have…

  6. Instructional Technology and Learning Resource Center-Based Community Education.

    ERIC Educational Resources Information Center

    Brown, James W.

    A survey of nonformal community education activities was conducted to determine specific use of media for identified educational and informational purposes. The results presented in this report are intended to provide resource information to professionals and paraprofessionals who ultimately may be employed in Learning Resource Center-Based…

  7. SSME testing technology at the John C. Stennis Space Center

    NASA Technical Reports Server (NTRS)

    Kynard, Mike; Dill, Glenn

    1991-01-01

    An effective capability for testing the Space Shuttle Main Engine is described. The test complex utilizes a number of sophisticated test stands, test support facilities, and control centers to conduct development testing and flight acceptance testing at both nominal and off-nominal conditions.

  8. Information for Our Partners | NCI Technology Transfer Center | TTC

    Cancer.gov

    CRADA PAYMENT OPTIONS: Electronic Payments by Wire Transfer via Fedwire, Mail a check to the Institute or Center, or Automated Clearing House (ACH)/Electronic Funds Transfer (ETF) payments via Pay.gov (NCI ONLY). | [google6f4cd5334ac394ab.html

  9. Research and Technology Report. Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Soffen, Gerald (Editor); Truszkowski, Walter (Editor); Ottenstein, Howard (Editor); Frost, Kenneth (Editor); Maran, Stephen (Editor); Walter, Lou (Editor); Brown, Mitch (Editor)

    1996-01-01

    This issue of Goddard Space Flight Center's annual report highlights the importance of mission operations and data systems covering mission planning and operations; TDRSS, positioning systems, and orbit determination; ground system and networks, hardware and software; data processing and analysis; and World Wide Web use. The report also includes flight projects, space sciences, Earth system science, and engineering and materials.

  10. Proposal and Justification for Establishing Strategic Technology Information Analysis Center.

    DTIC Science & Technology

    1981-12-04

    RESEARCH RADC CENTER FOR ANALYSIS SAMSO Avco SANDIA DYNETICS WPAFB/FTD ESL ASLAVSMR FACC NAVSURWEACEN GE (RESD, SSL, TEMPO) GRUMMAN GENERAL DYNAMICS B...Inst. P. 0. Drawer 23510 6220 Culebra Rd. San Antonio, TX 78234 6. Dynetics Inc. P. 0. Drawer B Huntsville, AL 35805 7. Rockwell International 6633

  11. Renal Cancer Biomarkers | NCI Technology Transfer Center | TTC

    Cancer.gov

    The National Cancer Institute's Laboratory of Proteomics and Analytical Technologies is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize diagnostic, therapeutic and prognostic cancer biomarkers from clinical specimens.

  12. Research and technology at the Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Cryogenic engineering, hypergolic engineering, hazardous warning, structures and mechanics, computer sciences, communications, meteorology, technology applications, safety engineering, materials analysis, biomedicine, and engineering management and training aids research are reviewed.

  13. Research and technology: 1994 annual report of the John F. Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    1994-01-01

    As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, the John F. Kennedy Space Center is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the Engineering Development Directorate laboratories, most of the KSC operations contractors, academia, and selected commercial industries - all working in a team effort within their own areas of expertise. This edition of the Kennedy Space Center Research and Technology 1994 Annual Report covers efforts of all these contributors to the KSC advanced technology development program, as well as our technology transfer activities. The Technology Programs and Commercialization Office (DE-TPO), (407) 867-3017, is responsible for publication of this report and should be contacted for any desired information regarding the advanced technology program.

  14. Research and Technology: 2003 Annual Report of the John F Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The John F. Kennedy Space Center (KSC) is America's Spaceport Technology Center. The KSC technology development program encompasses the efforts of the entire KSC team, consisting of Government and contractor personnel, working in partnership with academic institutions and commercial industry. KSC's assigned mission areas are space launch operations and spaceport and range technologies. KSC's technology development customers include current space transportation programs, future space transportation programs / initiatives, and enabling technical programs. The KSC Research and Technology 2003 Annual Report encompasses the efforts of contributors to the KSC advanced technology development program and KSC technology transfer activities. Dr. Dave Bartine, KSC Chief Technologist, (321) 867-7069, is responsible for publication of this report and should be contacted for any desired information regarding KSC's research and technology development activities.

  15. Center for Technology for Advanced Scientific Componet Software (TASCS)

    SciTech Connect

    Govindaraju, Madhusudhan

    2010-10-31

    Advanced Scientific Computing Research Computer Science FY 2010Report Center for Technology for Advanced Scientific Component Software: Distributed CCA State University of New York, Binghamton, NY, 13902 Summary The overall objective of Binghamton's involvement is to work on enhancements of the CCA environment, motivated by the applications and research initiatives discussed in the proposal. This year we are working on re-focusing our design and development efforts to develop proof-of-concept implementations that have the potential to significantly impact scientific components. We worked on developing parallel implementations for non-hydrostatic code and worked on a model coupling interface for biogeochemical computations coded in MATLAB. We also worked on the design and implementation modules that will be required for the emerging MapReduce model to be effective for scientific applications. Finally, we focused on optimizing the processing of scientific datasets on multi-core processors. Research Details We worked on the following research projects that we are working on applying to CCA-based scientific applications. 1. Non-Hydrostatic Hydrodynamics: Non-static hydrodynamics are significantly more accurate at modeling internal waves that may be important in lake ecosystems. Non-hydrostatic codes, however, are significantly more computationally expensive, often prohibitively so. We have worked with Chin Wu at the University of Wisconsin to parallelize non-hydrostatic code. We have obtained a speed up of about 26 times maximum. Although this is significant progress, we hope to improve the performance further, such that it becomes a practical alternative to hydrostatic codes. 2. Model-coupling for water-based ecosystems: To answer pressing questions about water resources requires that physical models (hydrodynamics) be coupled with biological and chemical models. Most hydrodynamics codes are written in Fortran, however, while most ecologists work in MATLAB. This

  16. Development of New Materials and Technologies for Welding and Surfacing at Research and Production Center "Welding Processes and Technologies"

    NASA Astrophysics Data System (ADS)

    Kozyrev, N. A.; Kryukov, R. E.; Galevsky, G. V.; Titov, D. A.; Shurupov, V. M.

    2015-09-01

    The paper provides description of research into the influence of new materials and technologies on quality parameters of welds and added metal carried out at research and production center «Welding processes and technologies». New welding technologies of tanks for northern conditions are considered, as well as technologies of submerged arc welding involving fluxing agents AN - 348, AN - 60, AN - 67, OK. 10.71 and carbon-fluorine containing additives, new flux cored wires and surfacing technologies, teaching programs and a trainer for welders are designed.

  17. Technology requirements to be addressed by the NASA Lewis Research Center Cryogenic Fluid Management Facility program

    NASA Technical Reports Server (NTRS)

    Aydelott, J. C.; Rudland, R. S.

    1985-01-01

    The NASA Lewis Research Center is responsible for the planning and execution of a scientific program which will provide advance in space cryogenic fluid management technology. A number of future space missions were identified that require or could benefit from this technology. These fluid management technology needs were prioritized and a shuttle attached reuseable test bed, the cryogenic fluid management facility (CFMF), is being designed to provide the experimental data necessary for the technology development effort.

  18. Costs of achieving live birth from assisted reproductive technology: a comparison of sequential single and double embryo transfer approaches

    PubMed Central

    Crawford, Sara; Boulet, Sheree L.; Mneimneh, Allison S.; Perkins, Kiran M.; Jamieson, Denise J.; Zhang, Yujia; Kissin, Dmitry M.

    2016-01-01

    Objective To assess treatment and pregnancy/infant-associated medical costs and birth outcomes for assisted reproductive technology (ART) cycles in a subset of patients using elective double embryo (ET) and to project the difference in costs and outcomes had the cycles instead been sequential single ETs (fresh followed by frozen if the fresh ET did not result in live birth). Design Retrospective cohort study using 2012 and 2013 data from the National ART Surveillance System. Setting Infertility treatment centers. Patient(s) Fresh, autologous double ETs performed in 2012 among ART patients younger than 35 years of age with no prior ART use who cryopreserved at least one embryo. Intervention(s) Sequential single and double ETs. Main Outcome Measure(s) Actual live birth rates and estimated ART treatment and pregnancy/infant-associated medical costs for double ET cycles started in 2012 and projected ART treatment and pregnancy/infant-associated medical costs if the double ET cycles had been performed as sequential single ETs. Result(s) The estimated total ART treatment and pregnancy/infant-associated medical costs were $580.9 million for 10,001 double ETs started in 2012. If performed as sequential single ETs, estimated costs would have decreased by $195.0 million to $386.0 million, and live birth rates would have increased from 57.7%–68.0%. Conclusion(s) Sequential single ETs, when clinically appropriate, can reduce total ART treatment and pregnancy/infant-associated medical costs by reducing multiple births without lowering live birth rates. PMID:26604068

  19. Future Directions in Rotorcraft Technology at Ames Research Center

    DTIC Science & Technology

    2000-05-01

    being pursued within the Army/NASA Rotorcraft Division. High Lift Airfoils and the Stall Free Rotor Unlike fixed wing aircraft, helicopter rotors have...pitch angle control inputs, a revolutionary new concept will become a reality - the Stall- Free Rotor. The implications for rotorcraft, beyond the...Rotorcraft Algorithm Development and Integrated Control Laws ( RADICL ) program, the U.S. Army, Sikorsky, ZF Luftfahrttechnik, and NASA Ames Research Center

  20. Center Director Bridges visits Disability Awareness and Action working Group Technology Fair

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Center Director Roy Bridges (standing, center) poses with members of the Disability Awareness and Action Working Group (DAAWG), which is holding the 1999 Technology Fair Oct. 20-21 at Kennedy Space Center. The Fair is highlighting vendors demonstrating mobility, hearing, vision and silent disability assistive technology. The purpose is to create an awareness of the types of technology currently available to assist people with various disabilities in the workplace. The theme is that of this year's National Disability Employment Awareness Month, 'Opening Doors to Ability.' Some of the vendors participating are Canine Companions for Independence, Goodwill Industries, Accessible Structures, Division of Blind Services, Space Coast Center for Independent Living, KSC Fitness Center and Delaware North Parks Services.

  1. Technology for libraries and information centers: A seminar in Greece, Portugal, and Turkey

    NASA Technical Reports Server (NTRS)

    Cotter, Gladys A.

    1992-01-01

    Information technologies are evolving at a rapid pace in today's world. But the electronic technologies needed to transform today's libraries and information centers into electronic 'libraries without walls', where an end-user has instantaneous access to all the information needed from a desktop workstation, have not yet arrived. Even so, there are many technologies available today that can be applied in the library/information center environment to yield increased productivity. However, not all technologies are right for or successful in every environment. Mission, budget, infrastructure, client profiles, and staff skills are a few of the 'environmental' issues that must be considered when selecting and introducing new technologies into a particular information center. Key technologies used in libraries today are reviewed; it can be used as background for targeting technologies that could be successfully implemented in your own environment to further service goals. Before focusing on a selection of technologies, you must first focus on the strategic goal of your organization. The same technology is not right for every library/information center. An overview of technologies that are readily available and can be applied today is presented.

  2. Marshall Space Flight Center Research and Technology Report 2015

    NASA Technical Reports Server (NTRS)

    Keys, A. S. (Compiler); Tinker, M. L. (Compiler); Sivak, A. D. (Compiler); Morris, H. C. (Compiler)

    2015-01-01

    The investments in technology development we made in 2015 not only support the Agency's current missions, but they will also enable new missions. Some of these projects will allow us to develop an in-space architecture for human space exploration; Marshall employees are developing and testing cutting-edge propulsion solutions that will propel humans in-space and land them on Mars. Others are working on technologies that could support a deep space habitat, which will be critical to enable humans to live and work in deep space and on other worlds. Still others are maturing technologies that will help new scientific instruments study the outer edge of the universe-instruments that will provide valuable information as we seek to explore the outer planets and search for life.

  3. Clinical outcomes after assisted reproductive technology in twin pregnancies: chorionicity-based comparison

    PubMed Central

    Sun, Luming; Zou, Gang; Wei, Xing; Chen, Yan; Zhang, Jun; Okun, Nanette; Duan, Tao

    2016-01-01

    The chorionicity–based evaluation of the perinatal risk in twin pregnancies after assisted reproductive technology (ART) is lacking. A retrospective review was performed of all twin pregnancies monitored prenatally and delivered at our hospital between 2010 and 2014. Chorionicity was diagnosed by ultrasound examination at first trimester and confirmed by postnatal pathology. Pregnancy and perinatal outcomes were prospectively recorded. Adjusted odds ratios (aOR) with 95% confidence intervals (CI) were calculated in a logistic regression model. A total of 1153 twin pregnancies were analyzed. The occurrence of preterm premature rupture of membranes (PPROM) was 3 times as frequent in monochorionic diamniotic (MCDA) twin pregnancies after ART as in those spontaneous counterparts (aOR 3.0; 95%CI 1.1–3.2). The prevalence of intrahepatic cholestasis of pregnancies (ICP) was significantly higher in dichorionic diamniotic (DCDA) twin pregnancies following ART compared to spontaneous DCDA pregnancies (aOR 3.3; 95%CI 1.3–5.6). Perinatal outcomes did not differ between two conception methods, either in MCDA or DCDA twin pregnancies. Based on differentiation of chorionicity, ART is associated with the increased risk of PPROM in MCDA twin pregnancies and with a higher rate of ICP in DCDA twin gestations. ART does not increase adversity of perinatal outcomes in twin pregnancies. PMID:27243373

  4. STOCKING THE GENETIC SUPERMARKET: REPRODUCTIVE GENETIC TECHNOLOGIES AND COLLECTIVE ACTION PROBLEMS

    PubMed Central

    Gyngell, Chris; Douglas, Thomas

    2015-01-01

    Reproductive genetic technologies (RGTs) allow parents to decide whether their future children will have or lack certain genetic predispositions. A popular model that has been proposed for regulating access to RGTs is the ‘genetic supermarket’. In the genetic supermarket, parents are free to make decisions about which genes to select for their children with little state interference. One possible consequence of the genetic supermarket is that collective action problems will arise: if rational individuals use the genetic supermarket in isolation from one another, this may have a negative effect on society as a whole, including future generations. In this article we argue that RGTs targeting height, innate immunity, and certain cognitive traits could lead to collective action problems. We then discuss whether this risk could in principle justify state intervention in the genetic supermarket. We argue that there is a plausible prima facie case for the view that such state intervention would be justified and respond to a number of arguments that might be adduced against that view. PMID:24720568

  5. Increased Length of Awareness of Assisted Reproductive Technologies Fosters Positive Attitudes and Acceptance among Women

    PubMed Central

    Fortin, Chelsea; Abele, Susanne

    2016-01-01

    Background The field of infertility medicine has witnessed a surge of scientific developments in recent years, but research on public attitudes towards infertility treatments has remained minimal. This study examined the social and demographic factors that affect women’s attitudes towards assisted reproductive technology (ART) in general, as well as their opinions of specific issues related to ART. Materials and Methods This cross-sectional study was conducted from March 2011 to April 2011 by means of an online survey administered to a sample of 287 women. Results Women with a longer length of awareness of ART had significantly greater attitudinal favorability towards ART. Political affiliation was also significantly related to general attitudes, as well as several specific aspects of ART issues. Conclusion The results of this study suggest that several factors influence attitudes that women hold in regards to ART. Identifying some of these factors serves as a crucial starting point for devising strategies to increase public acceptance of ART. PMID:27110326

  6. Stability of genomic imprinting in embryonic stem cells: lessons from assisted reproductive technology.

    PubMed

    Huntriss, John; Picton, Helen M

    2008-05-01

    Imprinted genes are expressed predominantly or exclusively from one allele only. This mode of gene expression makes the regulation of imprinted genes susceptible to epigenetic insults, which may in turn lead to disease. There is compelling experimental evidence that certain aspects of assisted reproductive technology (ART) such as in vitro cell culture may have adverse effects on the regulation of epigenetic information in mammalian embryos, including the disruption of imprinted genes and epigenetic regulators. Moreover, in humans, disorders of genomic imprinting have been reported in children conceived by ART. The derivation and in vitro culture of embryonic stem (ES) cells are potential points of origin for epigenetic abnormalities. There is evidence that defects of genomic imprinting occur in mouse embryonic stem cells, with similar data now emerging in related studies in non-human primate and human ES cells. It is therefore pertinent to rigorously assess the epigenetic status of all stem cells and their derivatives prior to their therapeutic use in humans. Focusing on the stability of genomic imprinting, this review discusses the current evidence for epigenetic disruption in mammalian embryonic stem cells in light of the epigenetic disruption observed in ART-derived mammalian embryos.

  7. A review of known imprinting syndromes and their association with assisted reproduction technologies.

    PubMed

    Amor, David J; Halliday, Jane

    2008-12-01

    An association between assisted reproduction technologies (ART) and abnormal genomic imprinting in humans has been recognized for several years; however, the magnitude of this risk and the spectrum of imprinting syndromes to which the risk applies remains unknown. Nine human imprinting syndromes have been identified but current evidence links ART with only three: Beckwith-Wiedemann syndrome, Angelman syndrome and the newly described maternal hypomethylation syndrome. There is currently a lack of evidence linking ART with the remaining six imprinting syndromes: Prader-Willi syndrome, Russell-Silver syndrome, maternal and paternal uniparental disomy of chromosome 14, pseudohypoparathyroidism type 1b and transient neonatal diabetes. Evidence from clinical reports suggests that the association between imprinting syndromes and ART may be restricted to syndromes where the imprinting change takes the form of hypomethylation on the maternal allele. In contrast, studies of gametes and early embryos suggest that ART can be associated with hypermethylation as well as hypomethylation, with imprinting changes occurring on paternal as well as maternal alleles. The health effects of ART-associated imprinting changes may also extend beyond the nine recognized imprinting syndromes.

  8. Risk of Chromosomal Abnormalities in Early Spontaneous Abortion after Assisted Reproductive Technology: A Meta-Analysis

    PubMed Central

    Qin, Jun-Zhen; Pang, Li-Hong; Li, Min-Qing; Xu, Jing; Zhou, Xing

    2013-01-01

    Background Studies on the risk of chromosomal abnormalities in early spontaneous abortion after assisted reproductive technology (ART) are relatively controversial and insufficient. Thus, to obtain a more precise evaluation of the risk of embryonic chromosomal abnormalities in first-trimester miscarriage after ART, we performed a meta-analysis of all available case–control studies relating to the cytogenetic analysis of chromosomal abnormalities in first-trimester miscarriage after ART. Methods Literature search in the electronic databases MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) based on the established strategy. Meta-regression, subgroup analysis, and Galbraith plots were conducted to explore the sources of heterogeneity. Results A total of 15 studies with 1,896 cases and 1,186 controls relevant to the risk of chromosomal abnormalities in first- trimester miscarriage after ART, and 8 studies with 601 cases and 602 controls evaluating frequency of chromosome anomaly for maternal age≥35 versus <35 were eligible for the meta-analysis. No statistical difference was found in risk of chromosomally abnormal miscarriage compared to natural conception and the different types of ART utilized, whereas the risk of fetal aneuploidy significantly increased with maternal age≥35 (OR 2.88, 95% CI: 1.74–4.77). Conclusions ART treatment does not present an increased risk for chromosomal abnormalities occurring in a first trimester miscarriage, but incidence of fetal aneuploidy could increase significantly with advancing maternal age. PMID:24130752

  9. Psychological stress and adjustment in pregnancy following assisted reproductive technology and spontaneous conception: A systematic review.

    PubMed

    Gourounti, Kleanthi

    2016-01-01

    The aim of this review was to examine studies describing the psychological stress and adjustment in pregnancy after an assisted reproductive technology (ART) treatment. A systematic search of the electronic databases was performed. This review considered only quantitative, primary studies in the English language, published during the period 2000-2014 and relevant to the objective. The population of interest was previously infertile pregnant women. Outcome variables were general anxiety, depressive symptoms, pregnancy-specific anxiety, quality of life, self-esteem, pregnancy attitudes and adjustment, and maternal-fetal attachment. Twenty studies met the inclusion and methodological criteria and were included in the review. The review revealed that compared to women who conceive naturally or to general norms, women who conceive after an in vitro fertilization treatment had greater pregnancy-specific anxiety, poorer quality of life, either the same or less depressive symptomatology, the same level of self-esteem, more positive attitudes toward pregnancy demands, and higher levels of maternal-fetal attachment. However, the evidence regarding the general anxiety levels in pregnancy after an ART treatment was inconclusive. Methodological limitations and differences across studies may explain the inconsistencies in their findings regarding the impact of ART. This review provides an insight into psychological reactions and adjustment in pregnancy after an ART treatment.

  10. DNA methylation reprogramming during oogenesis and interference by reproductive technologies: Studies in mouse and bovine models.

    PubMed

    Anckaert, Ellen; Fair, Trudee

    2015-06-01

    The use of assisted reproductive technology (ART) to overcome fertility problems has continued to increase since the birth of the first baby conceived by ART over 30 years ago. Similarly, embryo transfer is widely used as a mechanism to advance genetic gain in livestock. Despite repeated optimisation of ART treatments, pre- and postnatal outcomes remain compromised. Epigenetic mechanisms play a fundamental role in successful gametogenesis and development. The best studied of these is DNA methylation; the appropriate establishment of DNA methylation patterns in gametes and early embryos is essential for healthy development. Superovulation studies in the mouse indicate that specific ARTs are associated with normal imprinting establishment in oocytes, but abnormal imprinting maintenance in embryos. A similar limited impact of ART on oocytes has been reported in cattle, whereas the majority of embryo-focused studies have used cloned embryos, which do exhibit aberrant DNA methylation. The present review discusses the impact of ART on oocyte and embryo DNA methylation with regard to data available from mouse and bovine models.

  11. Processes involved in assisted reproduction technologies significantly increase sperm DNA fragmentation and phosphatidylserine translocation.

    PubMed

    Balasuriya, A; Serhal, P; Doshi, A; Harper, J C

    2014-03-01

    Sperm preparation techniques in assisted reproduction technologies (ART) are potential generators of exogenous stresses that cause additional DNA damage. DNA fragmentation tests, such as the sperm chromatin structure assay, involve freezing sperm samples in the absence of cryoprotectant. Thermal, oxidative stress (OS) and freezing are detrimental to sperm DNA fragmentation and phosphatidylserine (PS) translocation. The primary aim of this study was to subject mature sperm to environmental insults that normally occur during ART. We tested the hypotheses that OS, thermal stress and freeze-thawing caused sperm nuclear and membrane damage and that a positive correlation exists between PS translocation and DNA fragmentation. Sperm DNA integrity deteriorates in semen samples from men with advancing age and a sperm concentration of <15 m ml(-1) . The significant increase in sperm DNA fragmentation at 37 °C after merely 1 h is important clinically as semen liquefaction and short-term sperm storage in an ART cycle involve incubating samples at this temperature. Freezing without a cryoprotectant significantly increases the level of sperm nuclear damage, so it is important not to freeze neat semen prior to DNA fragmentation testing. This study highlights the importance of minimising the production of exogenous stresses during sperm preparation in ART.

  12. Short and long term outcomes of children conceived with assisted reproductive technology.

    PubMed

    Turkgeldi, Engin; Yagmur, Hande; Seyhan, Ayse; Urman, Bulent; Ata, Baris

    2016-12-01

    Despite their wide and global use, possible short and long-term effects of fertility treatments on children is not well-established. In this review, birth defects and perinatal complications and their relationship with assisted reproductive technology (ART), along with long-term effects of ART on cardiovascular system, metabolism, behavior, cognitive skills, and childhood cancers are discussed. Children conceived through ART are at increased risk for birth defects and perinatal complications such as preterm delivery, low birth weight and small for gestational age. Parental characteristics, underlying infertility etiology and ART procedures themselves may contribute to this. The long-term effects of ART are difficult to establish. Studies so far report that ART children have normal social, emotional, cognitive, and motor functions. Likewise, despite some minor inconsistencies in some studies, they do not seem to be at increased risk for childhood cancers. However, there are a number of studies that imply vascular system may be adversely affected by ART and its possible consequences should be further investigated with follow up studies. Large scale studies with long-term follow up periods are required to determine the effects of ART on conceived children.

  13. Efficient production of cynomolgus monkeys with a toolbox of enhanced assisted reproductive technologies

    PubMed Central

    Ma, Yunhan; Li, Jiayu; Wang, Ge; Ke, Qiong; Qiu, Sien; Gao, Liang; Wan, Haifeng; Zhou, Yang; Xiang, Andy Peng; Huang, Qunshan; Feng, Guoping; Zhou, Qi; Yang, Shihua

    2016-01-01

    The efficiency of assisted reproductive technologies (ARTs) in nonhuman primates is low due to no screening criterions for selecting sperm, oocyte, and embryo as well as its surrogate mothers. Here we analyzed 15 pairs of pregnant and non-pregnant cynomolgus monkeys, each pair of which received embryos from one batch of fertilized oocytes, and found ratio of endometrial to myometrial thicknesses in abdominal ultrasonic transverse section of uterus is a reliable indicator for selection of recipients for embryo transfer. We performed 305 ovarian stimulations in 128 female cynomolgus monkeys and found that ovarian stimulation can be performed in a whole year and repeated up to six times in the same monkey without deteriorating fertilization potential of eggs until a poor response to stimulation happened. Fertilization can be efficiently achieved with both conventional and piezo-driven intracytoplasmic sperm injection procedures. In semen collection, semen quality is higher with the penile robe electrical stimulus method compared with the rectal probe method. Moreover, caesarean section is an effective strategy for increasing baby survival rates of multiple pregnancies. These findings provide a practical guidance for the efficient use of ARTs, facilitating their use in genetic engineering of macaque monkeys for basic and translational neuroscience research. PMID:27173128

  14. Maternal and Live-birth Outcomes of Pregnancies following Assisted Reproductive Technology: A Retrospective Cohort Study

    PubMed Central

    Zhu, Linling; Zhang, Yu; Liu, Yifeng; Zhang, Runjv; Wu, Yiqing; Huang, Yun; Liu, Feng; Li, Meigen; Sun, Saijun; Xing, Lanfeng; Zhu, Yimin; Chen, Yiyi; Xu, Li; Zhou, Liangbi; Huang, Hefeng; Zhang, Dan

    2016-01-01

    This study was carried out to explore associations between assisted reproductive technology (ART) and maternal and neonatal outcomes compared with similar outcomes following spontaneously conceived births. We conducted a retrospective cohort study of pregnancies conceived by ART (N = 2641) during 2006–2014 compared to naturally conceived pregnancies (N = 5282) after matching for maternal age and birth year. Pregnancy complications, perinatal complications and neonatal outcomes of enrolled subjects were investigated and analysed by multivariate logistic regression. We found that pregnancies conceived by in vitro fertilization (IVF) were associated with a significantly increased incidence of gestational diabetes mellitus, gestational hypertension, preeclampsia, intrahepatic cholestasis of pregnancy, placenta previa, placental abruption, preterm premature rupture of membranes, placental adherence, postpartum haemorrhage, polyhydramnios, preterm labour, low birth weight, and small-for-date infant compared with spontaneously conceived births. Pregnancies conceived by intracytoplasmic sperm injection (ICSI) showed similar elevated complications, except some of the difference narrowed or disappeared. Singleton pregnancies or nulliparous pregnancies following ART still exhibited increased maternal and neonatal complications. Therefore, we conclude that pregnancies conceived following ART are at increased risks of antenatal complications, perinatal complications and poor neonatal outcomes, which may result from not only a higher incidence of multiple pregnancy, but also the manipulation involved in ART processes. PMID:27762324

  15. Impact of men's dairy intake on assisted reproductive technology outcomes among couples attending a fertility clinic.

    PubMed

    Xia, Wei; Chiu, Yu-Han; Afeiche, Myriam C; Williams, Paige L; Ford, Jennifer B; Tanrikut, Cigdem; Souter, Irene; Hauser, Russ; Chavarro, Jorge E

    2016-03-01

    Intake of full-fat dairy has been linked to lower semen quality but whether this leads to decreased fertility is unknown. To address this question, we prospectively evaluated the association of men's dairy intake with treatment outcomes of subfertile couples undergoing assisted reproductive technology (ART). We followed 142 men from couples undergoing infertility treatment with ART at an academic fertility centre between 2007 and 2014. Couples completed dietary assessments prior to treatment, and the female partners underwent a total of 248 ART cycles. Multivariable generalized linear mixed models were used to examine the association of dairy intake with fertilization, implantation, clinical pregnancy and live birth rates adjusting for age, body mass index, smoking status, total exercise time, dietary patterns, alcohol, caffeine, total energy intake, and female dairy intake. Intake of dairy foods, regardless of their fat content, was not associated with fertilization, implantation, clinical pregnancy or live birth rates. The adjusted live birth rates (95% confidence interval) for couples in increasing quartiles of men's dairy intake were 0.42 (0.25, 0.60), 0.25 (0.13, 0.42), 0.26 (0.15, 0.41), and 0.44 (0.27, 0.63) (p linear trend = 0.73). Results remained similar after adjustment for female partner intake of dairy foods. Overall, men's dairy intake was not associated with treatment outcomes of couples undergoing ART.

  16. Corpus luteal contribution to maternal pregnancy physiology and outcomes in assisted reproductive technologies.

    PubMed

    Conrad, Kirk P; Baker, Valerie L

    2013-01-15

    Investigations in the rat model of pregnancy indicate an important role for the corpus luteal (CL) hormone relaxin in the maternal circulatory and osmoregulatory changes in pregnancy, which are epitomized by profound vasodilation and modest hypoosmolality, respectively. In a pilot study of infertile women who became pregnant through donor eggs, in vitro fertilization, and embryo transfer, the gestational rise in glomerular filtration and fall in plasma osmolality were markedly subdued. Because these women were infertile, they lacked a CL and circulating relaxin (and possibly other vasoactive CL hormones). Based on these findings in pregnant rats and women, we hypothesize that infertile women conceiving through donor eggs will have overall subdued circulatory changes (e.g., attenuated reduction in systemic vascular resistance and subdued increase in cardiac output) particularly during early pregnancy when CL hormones predominate before the full development and maturation of the placenta. In contrast, infertile women conceiving by autologous eggs retrieved after ovarian stimulation and fresh embryo transfer may have a relatively hyperdynamic circulation due to the presence of many CL (up to 20 or more) and higher circulating levels of vasodilatory ovarian hormones such as relaxin. Emerging evidence suggests that women undergoing Assisted Reproductive Technologies (ART) have increased risk for adverse pregnancy outcomes such as preeclampsia and small for gestational-age babies. This increased risk may be partly caused by the maternal milieu, which is not physiological in ART pregnancies due to the abnormal status of the CL.

  17. Stocking the genetic supermarket: reproductive genetic technologies and collective action problems.

    PubMed

    Gyngell, Chris; Douglas, Thomas

    2015-05-01

    Reproductive genetic technologies (RGTs) allow parents to decide whether their future children will have or lack certain genetic predispositions. A popular model that has been proposed for regulating access to RGTs is the 'genetic supermarket'. In the genetic supermarket, parents are free to make decisions about which genes to select for their children with little state interference. One possible consequence of the genetic supermarket is that collective action problems will arise: if rational individuals use the genetic supermarket in isolation from one another, this may have a negative effect on society as a whole, including future generations. In this article we argue that RGTs targeting height, innate immunity, and certain cognitive traits could lead to collective action problems. We then discuss whether this risk could in principle justify state intervention in the genetic supermarket. We argue that there is a plausible prima facie case for the view that such state intervention would be justified and respond to a number of arguments that might be adduced against that view.

  18. [Extension of assisted reproductive technologies with donor sperm (ARTD) to non-medical indications].

    PubMed

    Jouannet, Pierre

    2014-01-01

    In France as in other countries, more and more single women and lesbian couples wish to become mothers. To carry through their parenting project they may consult a physician in France and often go abroad in order to get Assisted Reproductive Technologies with donor sperm (ARTD). Should ARTD be available to those women in France? The physician has not to take the decision. In such situations ARTD has no medical indication or contraindication. This assisted procreation raises many questions on children development and well-being. The results of studies made in other countries are often reassuring but their methodologies do not allow any conclusion to be drawn and grey areas persist. Therefore it should be necessary to develop a research effort in the field as it recently started in France. Would ARTD access to women without a male partner be legalized, the law should respect the ethical principles of non-payment and anonymity associated with donation of all body components. In any case, it should also allow an efficient medical care to be performed to ensure under the best conditions the well-being of the children and their mothers.

  19. Committee Opinion No 671 Summary: Perinatal Risks Associated With Assisted Reproductive Technology.

    PubMed

    2016-09-01

    Over the past decades, the use of assisted reproductive technology (ART) has increased dramatically worldwide and has made pregnancy possible for many infertile couples. Although the perinatal risks that may be associated with ART and ovulation induction are much higher in multifetal gestations, even singletons achieved with ART and ovulation induction may be at higher risk than singletons from naturally occurring pregnancies. However, it remains unclear to what extent these associations might be related to the underlying cause(s) of infertility. Before initiating ART or ovulation induction procedures, obstetrician-gynecologists and other health care providers should complete a thorough medical evaluation to ensure that patients are in good health and should counsel these women about the risks associated with treatment. Any maternal health problems or inherited conditions should be addressed. Couples at risk of passing genetic conditions on to their offspring, including those due to infertility-associated conditions, should be counseled appropriately. When a higher-order (triplet or more) multifetal pregnancy is encountered, the option of multifetal reduction should be discussed. In the case of a continuing higher-order multifetal pregnancy, ongoing obstetric care should be with an obstetrician-gynecologist or other obstetric care provider and at a facility capable of managing anticipated risks and outcomes.

  20. Committee Opinion No 671: Perinatal Risks Associated With Assisted Reproductive Technology.

    PubMed

    2016-09-01

    Over the past decades, the use of assisted reproductive technology (ART) has increased dramatically worldwide and has made pregnancy possible for many infertile couples. Although the perinatal risks that may be associated with ART and ovulation induction are much higher in multifetal gestations, even singletons achieved with ART and ovulation induction may be at higher risk than singletons from naturally occurring pregnancies. However, it remains unclear to what extent these associations might be related to the underlying cause(s) of infertility. Before initiating ART or ovulation induction procedures, obstetrician-gynecologists and other health care providers should complete a thorough medical evaluation to ensure that patients are in good health and should counsel these women about the risks associated with treatment. Any maternal health problems or inherited conditions should be addressed. Couples at risk of passing genetic conditions on to their offspring, including those due to infertility-associated conditions, should be counseled appropriately. When a higher-order (triplet or more) multifetal pregnancy is encountered, the option of multifetal reduction should be discussed. In the case of a continuing higher-order multifetal pregnancy, ongoing obstetric care should be with an obstetrician-gynecologist or other obstetric care provider and at a facility capable of managing anticipated risks and outcomes.

  1. Endometriosis-Related Infertility: The Role of the Assisted Reproductive Technologies

    PubMed Central

    Surrey, Eric S.

    2015-01-01

    The assisted reproductive technologies, particularly in vitro fertilization (IVF), represent the most efficient and successful means of overcoming infertility associated with endometriosis. Although older studies suggest that IVF outcomes are compromised in endometriosis patients, more contemporary reports show no differences compared to controls. The exception may be evidence of poorer outcomes and diminished ovarian response in women with advanced disease, particularly those with significant ovarian involvement or prior ovarian surgery. Prolonged pre-IVF cycle suppressive medical therapy, particularly gonadotropin releasing hormone agonists, appears to improve success rates in a subset of endometriosis patients. However, as of yet, there is no diagnostic marker to specifically identify those who would most benefit from this approach. Pre-IVF cycle surgical resection of nonovarian disease has not been consistently shown to improve outcomes with the possible exception of resection of deeply invasive disease, although the data is limited. Precycle resection of ovarian endometriomas does not have benefit and should only be performed for gynecologic indications. Indeed, there is a large body of evidence to suggest that this procedure may have a deleterious impact on ovarian reserve and response. A dearth of appropriately designed trials makes development of definitive treatment paradigms challenging. PMID:26240824

  2. 78 FR 65300 - Notice of Availability (NOA) for General Purpose Warehouse and Information Technology Center...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ... Technology Center Construction (GPW/IT)--Tracy Site-- Environmental Assessment AGENCY: Defense Logistics Agency, DoD. ACTION: Notice of Availability (NOA) for GPW/IT--Tracy Site-- Environmental...

  3. National Fuel Cell Technology Evaluation Center (NFCTEC); (NREL) National Renewable Energy Laboratory

    SciTech Connect

    Kurtz, Jennifer; Sprik, Sam

    2014-03-11

    This presentation gives an overview of the National Fuel Cell Technology Evaluation Center (NFCTEC), describes how NFCTEC benefits the hydrogen and fuel cell community, and introduces a new fuel cell cost/price aggregation project.

  4. OHIO INTERNATIONAL TELEVISION AND VIDEO FESTIVAL AWARD WINNERS FROM THE IMAGING TECHNOLOGY CENTER IT

    NASA Technical Reports Server (NTRS)

    2000-01-01

    OHIO INTERNATIONAL TELEVISION AND VIDEO FESTIVAL AWARD WINNERS FROM THE IMAGING TECHNOLOGY CENTER ITC KEVIN BURKE - BILL FLETCHER - GARY NOLAN - EMERY ADANICH FOR THE VIDEO ENTITLED ICING FOR REGIONAL AND CORPORATE PILOTS

  5. Project of space research and technology center in Engelhardt astronomical observatory

    NASA Astrophysics Data System (ADS)

    Nefedyev, Y.; Gusev, A.; Sherstukov, O.; Kascheev, R.; Zagretdinov, R.

    2012-09-01

    Today on the basis of Engelhardt astronomical observatory (EAO) is created Space research and technology center as consistent with Program for expansion of the Kazan University. The Centre has the following missions: • EDUCATION • SCIENCE • ASTRONOMICAL TOURISM

  6. Mouse Xenograft Model for Mesothelioma | NCI Technology Transfer Center | TTC

    Cancer.gov

    The National Cancer Institute is seeking parties interested in collaborative research to co-develop, evaluate, or commercialize a new mouse model for monoclonal antibodies and immunoconjugates that target malignant mesotheliomas. Applications of the technology include models for screening compounds as potential therapeutics for mesothelioma and for studying the pathology of mesothelioma.

  7. Co-Development Agreements | NCI Technology Transfer Center | TTC

    Cancer.gov

    The National Cancer Institute's TTC uses three different co-development agreements to help industry and academia interact and partner with National Institutes of Health laboratories and scientists to support technology development activities. | [google6f4cd5334ac394ab.html

  8. The Employee Invention Report (EIR) | NCI Technology Transfer Center | TTC

    Cancer.gov

    After making such a discovery, NCI researchers should immediately contact their Laboratory or Branch Chief and inform him or her of a possible invention and consult with your NCI TTC Technology Transfer Specialist about submitting an Employee Invention Report (EIR) Form. | [google6f4cd5334ac394ab.html

  9. Solid State Technology Branch of NASA Lewis Research Center

    NASA Technical Reports Server (NTRS)

    1992-01-01

    A collection of papers written by the members of the Solid State Technology Branch of NASA LeRC from Jun. 1991 - Jun. 1992 is presented. A range of topics relating to superconductivity, Monolithic Microwave Circuits (MMIC's), coplanar waveguides, and material characterization is covered.

  10. Collaborative Information Technology Center (CITC) for Rural Areas.

    ERIC Educational Resources Information Center

    Fontenot, Dean; Driskill, David A.

    The digital divide remains a formidable issue in rural areas where the only broadband access to the Internet may be at public schools or city governments. As the only locations in rural areas with adequate technological resources, schools, libraries, health facilities, and agricultural extension facilities can be places where citizens learn about…

  11. Water Reclamation Technology Development at Johnson Space Center

    NASA Technical Reports Server (NTRS)

    Callahan, Michael R.; Pickering, Karen

    2014-01-01

    Who We Are: A staff of approximately 14 BS, MS, and PhD-Level Engineers and Scientists with experience in Aerospace, Civil, Environmental, and Mechanical Engineering, Chemistry, Physical Science and Water Pollution Microbiology. Our Primary Objective: To develop the next generation water recovery system technologies that will support NASA's long duration missions beyond low-earth orbit.

  12. Integrating Technology into Classroom: The Learner-Centered Instructional Design

    ERIC Educational Resources Information Center

    Sezer, Baris; Karaoglan Yilmaz, Fatma Gizem; Yilmaz, Ramazan

    2013-01-01

    In this study, to present an instructional model by considering the existing models of instructional design (ARCS, ADDIE, ASSURE, Dick and Carey, Seels and Glasgow, Smith and Ragan etc.) with the nature of technology-based education and to reveal analysis, design, development, implementation, evaluation, and to revise levels with lower levels of…

  13. TEC Center: Linking Technology, Education and Cultural Diversity

    ERIC Educational Resources Information Center

    Hoter, Elaine; Shonfeld, Miri; Asmaa, N. Ganayem

    2012-01-01

    To many people, "Israel" is perceived as a "high-tech" nation, but in the same breath, as a "nation in conflict." So why not apply Israel's technological advantage to battle the multicultural conflict within? In this article, we will review the multicultural segregation in Israel, the traditional attempts to bring…

  14. Factors predicting the use of technology: findings from the Center for Research and Education on Aging and Technology Enhancement (CREATE).

    PubMed

    Czaja, Sara J; Charness, Neil; Fisk, Arthur D; Hertzog, Christopher; Nair, Sankaran N; Rogers, Wendy A; Sharit, Joseph

    2006-06-01

    The successful adoption of technology is becoming increasingly important to functional independence. The present article reports findings from the Center for Research and Education on Aging and Technology Enhancement (CREATE) on the use of technology among community-dwelling adults. The sample included 1,204 individuals ranging in age from 18-91 years. All participants completed a battery that included measures of demographic characteristics, self-rated health, experience with technology, attitudes toward computers, and component cognitive abilities. Findings indicate that the older adults were less likely than younger adults to use technology in general, computers, and the World Wide Web. The results also indicate that computer anxiety, fluid intelligence, and crystallized intelligence were important predictors of the use of technology. The relationship between age and adoption of technology was mediated by cognitive abilities, computer self-efficacy, and computer anxiety. These findings are discussed in terms of training strategies to promote technology adoption.

  15. Factors Predicting the Use of Technology: Findings From the Center for Research and Education on Aging and Technology Enhancement (CREATE)

    PubMed Central

    Czaja, Sara J.; Charness, Neil; Fisk, Arthur D.; Hertzog, Christopher; Nair, Sankaran N.; Rogers, Wendy A.; Sharit, Joseph

    2006-01-01

    The successful adoption of technology is becoming increasingly important to functional independence. The present article reports findings from the Center for Research and Education on Aging and Technology Enhancement (CREATE) on the use of technology among community-dwelling adults. The sample included 1,204 individuals ranging in age from 18–91 years. All participants completed a battery that included measures of demographic characteristics, self-rated health, experience with technology, attitudes toward computers, and component cognitive abilities. Findings indicate that the older adults were less likely than younger adults to use technology in general, computers, and the World Wide Web. The results also indicate that computer anxiety, fluid intelligence, and crystallized intelligence were important predictors of the use of technology. The relationship between age and adoption of technology was mediated by cognitive abilities, computer self-efficacy, and computer anxiety. These findings are discussed in terms of training strategies to promote technology adoption. PMID:16768579

  16. Teaching the originator to make whoopie. [ORNL Engineering Technology Division Word Processing Center

    SciTech Connect

    Not Available

    1980-01-01

    A small Word Processing (Whoopie) Center was established in March 1979, as part of the Engineering Technology Division (ETD), Oak Ridge National Laboratory. Reports preparation information revealed many training items for editors and word processors but none for informing the author. The ETD Word Processing Center has begun a series of sessions with each section in ETD to help originators become more familiar with the Center and its equipment. 5 figures.

  17. Between Technological Endorsement and Resistance: The State of Online Writing Centers

    ERIC Educational Resources Information Center

    Neaderhiser, Stephen; Wolfe, Joanna

    2009-01-01

    Over the past two decades, writing centers have steadily been expanding services and materials they offer online. The way students write and communicate about their writing continues to change, and the writing center has increasingly been looked upon as a site through which technology and writing have the ability to converge in the form of…

  18. Technology-Based Biliteracy Centers for the 21st Century Learner

    ERIC Educational Resources Information Center

    Mercuri, Sandra; Ramos, Laura

    2014-01-01

    The purpose of this reflective article is to present an alternative that incorporates the four language skills in all content areas through technology-based dual-language centers for emergent bilinguals at the elementary level. The authors propose a matrix to plan the centers and include three examples to facilitate language transfer in English…

  19. Personalized Integrated Educational System: Technology Functions for the Learner- Centered Paradigm of Education

    ERIC Educational Resources Information Center

    Reigeluth, Charles M.; Aslan, Sinem; Chen, Zengguan; Dutta, Pratima; Huh, Yeol; Lee, Dabae; Lin, Chun-Yi; Lu, Ya-Huei; Min, Mina; Tan, Verily; Watson, Sunnie Lee; Watson, William R.

    2015-01-01

    The learner-centered paradigm of instruction differs in such fundamental ways from the teacher-centered paradigm that it requires technology to serve very different functions. In 2006, a research team at Indiana University began to work on identifying those functions and published their results in 2008. Subsequently, the team elaborated and…

  20. The Efficiency and Effectiveness of the K-12 Energy Technology Education Promotion Centers in Taiwan

    ERIC Educational Resources Information Center

    Lee, Lung-Sheng

    2013-01-01

    In order to promote energy literacy for graders K-12, the Ministry of Education (MOE) in Taiwan initiated a K-12 Energy Technology Education Project in September 2010. This 40-month project has one project office affiliated to a university, and 18 promotion centers affiliated to 18 schools--including 5 regional centers for upper-secondary schools…

  1. Appalachian Teacher Center for Teachers in the Technologies. Annual Progress Report, 1975.

    ERIC Educational Resources Information Center

    McCrory, David L.

    The Center for Teachers in the Technologies was designed to upgrade teacher competence in: (1) instructional strategies, (2) diagnostic skills, (3) background information, and (4) curriculum. Viewing itself as a service organ for teachers, the center responded to needs articulated by the educational community by designing and delivering brief,…

  2. Research and Technology at the John F. Kennedy Space Center 1993

    NASA Technical Reports Server (NTRS)

    1993-01-01

    As the NASA Center responsible for assembly, checkout, servicing, launch, recovery, and operational support of Space Transportation System elements and payloads, the John F. Kennedy Space Center is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the Engineering Development Directorate laboratories, most of the KSC operations contractors, academia, and selected commercial industries - all working in a team effort within their own areas of expertise. This edition of the Kennedy Space Center Research and Technology 1993 Annual Report covers efforts of all these contributors to the KSC advanced technology development program, as well as our technology transfer activities. Major areas of research include material science, advanced software, industrial engineering, nondestructive evaluation, life sciences, atmospheric sciences, environmental technology, robotics, and electronics and instrumentation.

  3. CD-ROM technology at the EROS data center

    USGS Publications Warehouse

    Madigan, Michael E.; Weinheimer, Mary C.

    1993-01-01

    The vast amount of digital spatial data often required by a single user has created a demand for media alternatives to 1/2" magnetic tape. One such medium that has been recently adopted at the U.S. Geological Survey's EROS Data Center is the compact disc (CD). CD's are a versatile, dynamic, and low-cost method for providing a variety of data on a single media device and are compatible with various computer platforms. CD drives are available for personal computers, UNIX workstations, and mainframe systems, either directly connected, or through a network. This medium furnishes a quick method of reproducing and distributing large amounts of data on a single CD. Several data sets are already available on CD's, including collections of historical Landsat multispectral scanner data and biweekly composites of Advanced Very High Resolution Radiometer data for the conterminous United States. The EROS Data Center intends to provide even more data sets on CD's. Plans include specific data sets on a customized disc to fulfill individual requests, and mass production of unique data sets for large-scale distribution. Requests for a single compact disc-read only memory (CD-ROM) containing a large volume of data either for archiving or for one-time distribution can be addressed with a CD-write once (CD-WO) unit. Mass production and large-scale distribution will require CD-ROM replication and mastering.

  4. Quality of parenting in families created by the new reproductive technologies: a brief report of preliminary findings.

    PubMed

    Golombok, S; Cook, R; Bish, A; Murray, C

    1993-01-01

    The creation of families by means of the new reproductive technologies has raised important questions about the consequences for parent-child relationships, particularly where gamete donation has been used to conceive the child. Preliminary findings are presented of a study of the quality of parenting in families created as a result of the two most widely used reproductive technologies, in vitro fertilization and donor insemination, in comparison with a control group of families with a naturally conceived child and a control group of adoptive families. The quality of parenting was assessed using a standardized interview with the mother, and mothers and fathers completed questionnaire measures of stress associated with parenting. The results showed that the quality of parenting in families with a child conceived by assisted conception is superior to that shown by families with a naturally conceived child. The findings are discussed in terms of their implications for understanding the role of genetic ties in parent-child relationships.

  5. Development of a National Center for Hydrogen Technology

    SciTech Connect

    Jay C. Almlie; Bruce Wood; Rich Schlupp

    2007-03-01

    In November 2005, the Energy & Environmental Research Center (EERC), ePowerSynergies, Inc. (ePSI), and Resurfice Corporation teamed to develop, produce, and demonstrate the world's first and only fuel cell-powered ice resurfacer. The goals of this project were: {sm_bullet} To educate the public on the readiness, practicality, and safety of fuel cells powered by hydrogen fuel and {sm_bullet} To establish a commercialization pathway in an early-adopter, niche market. The vehicle was developed and produced in a short 3-month span. The vehicle made its world debut at U.S. Senator Byron Dorgan's (D-ND) 2005 Hydrogen Energy Action Summit. Subsequently, the vehicle toured North America appearing at numerous public events and conferences, receiving much attention from international media outlets.

  6. Crossing the Great Divide: Adoption of New Technologies, Therapeutics and Diagnostics at Academic Medical Centers

    ERIC Educational Resources Information Center

    DeMonaco, Harold J.; Koski, Greg

    2007-01-01

    The role of new technology in healthcare continues to expand from both the clinical and financial perspectives. Despite the importance of innovation, most academic medical centers do not have a clearly defined process for technology assessment. Recognizing the importance of new drugs, diagnostics and procedures in the care of patients and in the…

  7. Investigating "The Coolest School in America": How Technology Is Used in a Learner-Centered School

    ERIC Educational Resources Information Center

    Aslan, Sinem; Reigeluth, Charles M.

    2016-01-01

    Reigeluth et al. ("Educ Technol" 48(6):32-39, 2008) proposed major and secondary functions for educational technology systems for the learner-centered paradigm of education. However, the functions proposed should be formatively evaluated and revised using a variety of cases to develop a better understanding of how technology can support…

  8. Vaccines for HIV | NCI Technology Transfer Center | TTC

    Cancer.gov

    The development of an effective HIV vaccine has been an ongoing area of research. The high variability in HIV-1 virus strains has represented a major challenge in successful development. Ideally, an effective candidate vaccine would provide protection against the majority of clades of HIV. Two major hurdles to overcome are immunodominance and sequence diversity. This vaccine utilizes a strategy for overcoming these two issues by identifying the conserved regions of the virus and exploiting them for use in a targeted therapy. NCI seeks licensees and/or research collaborators to commercialize this technology, which has been validated in macaque models.

  9. Technology transfer at the University of Nebraska Medical Center.

    PubMed

    Matsuo, Kulia; Runge, Henry J; Miller, David J; Barak-Bernhagen, Mary A; Boedeker, Ben H

    2011-01-01

    The course of developing a new product from an idea is a complicated process. This paper will discuss that process, in detail, from conception to product. We approach this by first discussing what the inventor must do begin the process of developing his or her idea, and then two pathways that occur simultaneously: the Technology Transfer process of patenting, marketing, and licensing the invention; and the engineering process of developing, modifying, and manufacturing the invention. Although the process is lengthy and most ideas never become a marketed product, there are those few ideas that do become realized into marketed products.

  10. Environmental Technology Verification (ETV) Program: Site Characterization and Monitoring Technologies Center

    EPA Pesticide Factsheets

    The ETV Site Characterization and Monitoring Technology Pilot is composed of EPA, DoD, DOE, other Federal agencies, state regulators, technology evaluation and verification entities, and potential end users of these technologies to facilitate independent..

  11. A Deliberate and Rigorous Approach to Development of Patient-centered Technologies

    PubMed Central

    Wolpin, Seth; Stewart, Mark

    2011-01-01

    Objectives Many technologies intended for patient use are never developed or evaluated with principles of user-centered design. In this review, we explore different approaches to assessing usability and acceptability, drawn from selected exemplar studies in the health sciences literature. Data sources Peer-reviewed research manuscripts were selected from Medline and other data sources accessible through pubmed.gov. We also present a framework for developing patient-centered technologies that we recently employed. Conclusions While there are studies utilizing principles of user-centered design, many more do not report formative usability testing results and may only report post-hoc satisfaction surveys. Consequently, adoption by user groups may be limited. Implications for Nursing Practice We encourage nurses in practice to look for and examine usability testing results prior to considering implementation of any patient-centered technology. PMID:21783009

  12. Center Director Bridges visits Disability Awareness and Action working Group Technology Fair

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Center Director Roy Bridges stops to talk to one of the vendors at the Disability Awareness and Action Working Group (DAAWG) Technology Fair being held Oct. 20-21 at Kennedy Space Center. With him at the far left is Sterling Walker, director of Engineering Development at KSC and chairman of DAAWG, and Nancie Strott, a multi-media specialist with Dynacs and chairperson of the Fair; at the right is Carol Cavanaugh, with KSC Public Services. The Fair is highlighting vendors demonstrating mobility, hearing, vision and silent disability assistive technology. The purpose is to create an awareness of the types of technology currently available to assist people with various disabilities in the workplace. The theme is that of this year's National Disability Employment Awareness Month, 'Opening Doors to Ability.' Some of the vendors participating are Canine Companions for Independence, Goodwill Industries, Accessible Structures, Division of Blind Services, Space Coast Center for Independent Living, KSC Fitness Center and Delaware North Parks Services.

  13. Spatial interpretation of NASA's Marshall Space Flight Center Payload Operations Control Center using virtual reality technology

    NASA Technical Reports Server (NTRS)

    Lindsey, Patricia F.

    1993-01-01

    In its search for higher level computer interfaces and more realistic electronic simulations for measurement and spatial analysis in human factors design, NASA at MSFC is evaluating the functionality of virtual reality (VR) technology. Virtual reality simulation generates a three dimensional environment in which the participant appears to be enveloped. It is a type of interactive simulation in which humans are not only involved, but included. Virtual reality technology is still in the experimental phase, but it appears to be the next logical step after computer aided three-dimensional animation in transferring the viewer from a passive to an active role in experiencing and evaluating an environment. There is great potential for using this new technology when designing environments for more successful interaction, both with the environment and with another participant in a remote location. At the University of North Carolina, a VR simulation of a the planned Sitterson Hall, revealed a flaw in the building's design that had not been observed during examination of the more traditional building plan simulation methods on paper and on computer aided design (CAD) work station. The virtual environment enables multiple participants in remote locations to come together and interact with one another and with the environment. Each participant is capable of seeing herself and the other participants and of interacting with them within the simulated environment.

  14. Two-Phase Technology at NASA/Johnson Space Center

    NASA Technical Reports Server (NTRS)

    Ungar, Eugene K.; Nicholson, Leonard S. (Technical Monitor)

    1999-01-01

    Since the baseline International Space Station (ISS) External Active Thermal Control System (EATCS) was changed from a two-phase mechanically pumped system to a single phase cascade system in the fall of 1993, two-phase EATCS research has continued at a low level at JSC. One of-the lessons of the ISS EATCS selection was that two-phase thermal control systems must have significantly lower power than comparable single phase systems to overcome their larger radiator area, larger line and fluid mass, and perceived higher technical risk. Therefore, research at JSC has concentrated on low power mechanically pumped two-phase EATCSs. In the presentation, the results of a study investigating the trade of single and two-phase mechanically pumped EATCSs for space vehicles will be summarized. The low power two-phase mechanically pumped EATCS system under development at JSC will be described in detail and the current design status of the subscale test unit will be reviewed. Also, performance predictions for a full size EATCS will be presented. In addition to the discussion of two-phase mechanically pumped EATCS development at JSC, two-phase technologies under development for biological water processing will be discussed. These biological water processor technologies are being prepared for a 2001 flight experiment and subsequent usage on the TransHab module on the International Space Station.

  15. A Review of The Society for Assisted Reproductive Technology Embryo Grading System and Proposed Modification

    PubMed Central

    Hossain, Amjad; Phelps, John; Agarwal, Ashok; Sanz, Eduardo; Mahadevan, Maha

    2016-01-01

    The Society for Assisted Reproductive Technology (SART) method of embryo grad- ing is unique, simple, and widely practiced, and its use has been mandatory for SART membership programs since 2010. Developed by SART in 2006, the current embryo grading system categories, “good, fair, and poor,” are limited because they do not describe the best 1-2 embryos in the interest of keeping pace with the shift in clinical practice to be more selective and to transfer fewer embryos. This inspired us to conduct a review on the SART embryo grading system. In this retrospective study, the literature on evaluation of human embryo quality in gen- eral, and the SART method of evaluation in particular, were reviewed for the period of 2000 to 2014. A multifaceted search pertaining to methods of embryo grading and trans- fer using a combination of relevant terms [embryo, mammalian, embryo transfer, grade, grading, morphology, biomarkers, SART, and in vitro fertilization (IVF)] was performed. The inclusion and exclusion in this review were dictated by the aim and scope of the study. Two investigators independently assessed the studies and extracted information. A total of 61 articles were reviewed. Very few studies have evaluated the efficacy of the SART embryo grading method. The present study suggests the necessity for revision of the current SART grading system. The system, as it is now, lacks criteria for describing the cohort specific best embryo and thus is of limited use in single embryo transfer. The study foresees heightened descriptive efficiency of the SART system by implementing the proposed changes. Strengths and weaknesses of the SART embryo grading were identified. Ideas for selecting the best cohort-specific embryo have been discussed, which may trigger methodological improvement in SART and other embryo grading systems. PMID:27441045

  16. Culture media influenced laboratory outcomes but not neonatal birth weight in assisted reproductive technology.

    PubMed

    Yin, Tai-lang; Zhang, Yi; Li, Sai-jiao; Zhao, Meng; Ding, Jin-li; Xu, Wang-ming; Yang, Jing

    2015-12-01

    Whether the type of culture media utilized in assisted reproductive technology has impacts on laboratory outcomes and birth weight of newborns in in-vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) was investigated. A total of 673 patients undergoing IVF/ICSI and giving birth to live singletons after fresh embryo transfer on day 3 from Jan. 1, 2010 to Dec. 31, 2012 were included. Three types of culture media were used during this period: Quinn's Advantage (QA), Single Step Medium (SSM), and Continuous Single Culture medium (CSC). Fertilization rate (FR), normal fertilization rate (NFR), cleavage rate (CR), normal cleavage rate (NCR), good-quality embryo rate (GQER) and neonatal birth weight were compared using one-way ANOVA and χ (2) tests. Multiple linear regression analysis was performed to determine the impact of culture media on laboratory outcomes and birth weight. In IVF cycles, GQER was significantly decreased in SSM medium group as compared with QA or CSC media groups (63.6% vs. 69.0% in QA; vs. 71.3% in CSC, P=0.011). In ICSI cycles, FR, NFR and CR were significantly lower in CSC medium group than in other two media groups. No significant difference was observed in neonatal birthweight among the three groups (P=0.759). Multiple linear regression analyses confirmed that the type of culture medium was correlated with FR, NFR, CR and GQER, but not with neonatal birth weight. The type of culture media had potential influences on laboratory outcomes but did not exhibit an impact on the birth weight of singletons in ART.

  17. The impact of assisted reproductive technologies on the genome and epigenome of the newborn.

    PubMed

    Kochanski, A; Merritt, T A; Gadzinowski, J; Jopek, A

    2013-01-01

    The question of genetic alterations resulting from assisted reproductive technologies (ART) in humans is examined within the organization of the human genome. Increased rates of birth defects have been reported among children conceived using ART; however, questions remain and controversy exists regarding how "infertility" predisposes to birth defects. ART has been shown to be associated with an increased number of chromosomal alterations especially in the X chromosome. There is increased risk for embryonal tumors among ART conceived children, as well as, imprinting disorders (Beckwith-Wiedemann and Angelman Syndromes). Genetic studies of children conceived using ART reveal a larger (genome-wide) scale of methylation defects that encompass hundreds of genes. Genes involved in carcinogenesis and developmental pathways appear altered and may impact on later development of chronic illness, although these data are very preliminary. ART may create novel mutations by different chromosomal and molecular mechanisms; however, these techniques also enable propagation of pre-existing mutations that are associated with impaired fertility. While older maternal age is often associated with female infertility and chromosomal aneuploidy, sperm from older men have more new gene mutations. The prevalence of birth defects is increased when ART is used for conception. These data are summarized by large meta-analyses or from multi-year national registries. Whether the increased number of birth defects is due to ART procedures themselves or are a consequence of the impaired fertility of the parents is discussed. Long-term evaluation of children conceived using ART and/or ovarian hyper-stimulation is needed to determine whether alterations during embryonic development may increase the prevalence of chronic diseases in adulthood.

  18. Assisted reproductive technology and pregnancy-related hypertensive complications: a systematic review.

    PubMed

    Thomopoulos, C; Tsioufis, C; Michalopoulou, H; Makris, T; Papademetriou, V; Stefanadis, C

    2013-03-01

    Hypertensive complications in pregnancy are the leading cause of maternal morbidity, at least in the developed countries. In recent years, infertility issues are managed with ever growing therapeutic options namely assisted reproductive technologies (ART), which improve the ratio of successful induction of pregnancy. It is still debated whether various ART modalities are associated with adverse pregnancy outcomes, including hypertensive complications, particularly with higher incidence of preeclampsia. The main source of controversy stems from the diversity of effect modifiers modulating the association between ART-oriented pregnancy and hypertensive disorders. Indeed, women undergoing an ART procedure are affected by diverse causes of infertility, are frequently characterized by different genetic patterns with respect to their artificially conceived embryo and experienced multiple gestations. In order to investigate whether ART modalities are associated with increased incidence of hypertensive complications in pregnancy, we reviewed all published studies carried out before the end of 2010 and identified in the PubMed database. Among the 47 studies finally selected and by acknowledging the potential of shortcomings related to the different study design and populations, the overall evidence suggests that ART-oriented pregnancies-especially the in-vitro fertilization techniques-are accompanied by increased risk for gestational hypertension and preeclampsia as compared with non-ART pregnancies, even after adjustment for confounders. Multiple gestations, advanced age and underlying polycystic ovary syndrome resulted in constant confounders of the questioned association. Reducing multiple gestations by implementing single embryo techniques might be the therapeutic limiting step to lower the rate of hypertensive complications in assisted pregnancies.

  19. Dynamic regulation of DNA methyltransferases in human oocytes and preimplantation embryos after assisted reproductive technologies.

    PubMed

    Petrussa, Laetitia; Van de Velde, Hilde; De Rycke, Martine

    2014-09-01

    DNA methylation is a key epigenetic modification which is essential for normal embryonic development. Major epigenetic reprogramming takes place during gametogenesis and in the early embryo; the complex DNA methylation patterns are established and maintained by DNA methyltransferases (DNMTs). However, the influence of assisted reproductive technologies (ART) on DNA methylation reprogramming enzymes has predominantly been studied in mice and less so in human oocytes and embryos. The expression and localization patterns of the four known DNMTs were analysed in human oocytes and IVF/ICSI embryos by immunocytochemistry and compared between a reference group of good quality fresh embryos and groups of abnormally developing embryos or embryo groups after cryopreservation. In humans, DNMT1o rather than DNMT1s seems to be the key player for maintaining methylation in early embryos. DNMT3b, rather than DNMT3a and DNMT3L, appears to ensure global DNA remethylation in the blastocysts before implantation. DNMT3L, an important regulator of maternal imprint methylation in mouse, was not detected in human oocytes (GV, MI and MII stage). Our study confirms the existence of species differences for mammalian DNA methylation enzymes. In poor quality fresh embryos, the switch towards nuclear DNMT3b expression was delayed and nuclear DNMT1, DNMT1s and DNMT3b expression was less common. Compared with the reference embryos, a smaller number of cryopreserved embryos showed nuclear DNMT1, while a delayed switch to nuclear DNMT3b and an extended DNMT1s temporal expression pattern were also observed. The spatial and temporal expression patterns of DNMTs seem to be disturbed in abnormally developing embryos and in embryos that have been cryopreserved. Further research must be performed in order to understand whether the potentially disturbed embryonic DNMT expression after cryopreservation has any long-term developmental consequences.

  20. Assisted reproductive technology in Europe, 2007: results generated from European registers by ESHRE

    PubMed Central

    de Mouzon, J.; Goossens, V.; Bhattacharya, S.; Castilla, J.A.; Ferraretti, A.P.; Korsak, V.; Kupka, M.; Nygren, K.G.; Andersen, A. Nyboe

    2012-01-01

    BACKGROUND This 11th European IVF-monitoring report presents the results of assisted reproductive technology (ART) treatments initiated in Europe during 2007. METHODS From 33 countries, 1029 clinics reported 493 184 treatment cycles: IVF (120 761), ICSI (256 642), frozen embryo replacement (91 145), egg donation (15 731), preimplantation genetic diagnosis/preimplantation genetic screening (4638), in vitro maturation (660) and frozen oocytes replacements (3607). Overall, this represents a 7.6% increase since 2006, mostly related to an increase in all registers. IUI using husband/partner's (IUI-H) and donor (IUI-D) semen was reported from 23 countries: 142 609 IUI-H (+6.2%) and 26 088 IUI-D (+7.2%). RESULTS In 18 countries where all clinics reported, 376 971 ART cycles were performed in a population of 425.6million (886 cycles per million). The clinical pregnancy rates per aspiration and per transfer were 29.1 and 32.8% for IVF, and 28.6 and 33.0% for ICSI. Delivery rate after IUI-H was 10.2% in women aged < 40 years. In IVF/ICSI cycles, 1, 2, 3 and ≥4 embryos were transferred in 21.4, 53.4, 22.7 and 2.5% of cycles, with no decline in the number of embryos per transfer since 2006. The proportion of multiple deliveries (22.3: 21.3% twin and 1.0% triplet), did not decrease compared with 2006 (20.8%) and 2005 (21.8%). In women < 40 years undergoing IUI-H, twin deliveries occurred in 11.7% and triplets in 0.5%. CONCLUSIONS In comparison with previous years, the reported number of ART cycles in Europe increased in 2007; pregnancy rates increased marginally, but the earlier decline in the number of embryos transferred and multiple births did not continue. PMID:22343707

  1. Assisted reproductive technology and the risk of preterm birth among primiparas

    PubMed Central

    Dunietz, Galit Levi; Holzman, Claudia; McKane, Patricia; Li, Chenxi; Boulet, Sheree L.; Todem, David; Kissin, Dmitry M.; Copeland, Glenn; Bernson, Dana; Sappenfield, William M.; Diamond, Michael P.

    2015-01-01

    Objective To investigate the risk of preterm birth among liveborn singletons to primiparas who conceived with assisted reproductive technology (ART) using four mutually exclusive categories of infertility (female infertility only, male infertility only, female and male infertility, and unexplained infertility) and to examine preterm birth risk along the gestational age continuum. Design Retrospective cohort study. Setting Not applicable. Patient(s) Singletons born to primiparas who conceived with or without ART. Intervention(s) None. Main Outcome Measure(s) Preterm (<37 weeks’ gestation) and preterm/early term birth <39 weeks’ gestation). Result(s) For the male infertility only, female infertility only, combined male and female infertility, and unexplained infertility groups, ART-conceived singletons were significantly more likely than non-ART singletons to be born preterm: adjusted odds ratio (aOR) 1.24 (95% CI, 1.13, 1.37), aOR 1.60 (95% CI, 1.50, 1.70), aOR 1.49 (95% CI, 1.35, 1.64), and aOR 1.26 (1.12, 1.43) respectively. Among infants whose mothers were diagnosed with infertility, the odds of preterm birth were highest between 28–30 weeks [female infertility only, aOR 1.95 (95% CI, 1.59, 2.39); male and female infertility: 2.21 (95% CI, 1.62, 3.00)] compared with infants in the general population. Within the ART population, singletons of couples with female infertility only were more likely to be born preterm than singletons born to couples with other infertility diagnoses. Conclusion(s) Among singleton births to primiparas, those conceived with ART had an increased risk for preterm birth, even when only the male partner had been diagnosed with infertility. The risk of preterm birth for ART-conceived infants whose mothers were diagnosed with infertility included the earliest deliveries. PMID:25707336

  2. A Review of The Society for Assisted Reproductive Technology Embryo Grading System and Proposed Modification.

    PubMed

    Hossain, Amjad; Phelps, John; Agarwal, Ashok; Sanz, Eduardo; Mahadevan, Maha

    2016-01-01

    The Society for Assisted Reproductive Technology (SART) method of embryo grad- ing is unique, simple, and widely practiced, and its use has been mandatory for SART membership programs since 2010. Developed by SART in 2006, the current embryo grading system categories, "good, fair, and poor," are limited because they do not describe the best 1-2 embryos in the interest of keeping pace with the shift in clinical practice to be more selective and to transfer fewer embryos. This inspired us to conduct a review on the SART embryo grading system. In this retrospective study, the literature on evaluation of human embryo quality in gen- eral, and the SART method of evaluation in particular, were reviewed for the period of 2000 to 2014. A multifaceted search pertaining to methods of embryo grading and trans- fer using a combination of relevant terms [embryo, mammalian, embryo transfer, grade, grading, morphology, biomarkers, SART, and in vitro fertilization (IVF)] was performed. The inclusion and exclusion in this review were dictated by the aim and scope of the study. Two investigators independently assessed the studies and extracted information. A total of 61 articles were reviewed. Very few studies have evaluated the efficacy of the SART embryo grading method. The present study suggests the necessity for revision of the current SART grading system. The system, as it is now, lacks criteria for describing the cohort specific best embryo and thus is of limited use in single embryo transfer. The study foresees heightened descriptive efficiency of the SART system by implementing the proposed changes. Strengths and weaknesses of the SART embryo grading were identified. Ideas for selecting the best cohort-specific embryo have been discussed, which may trigger methodological improvement in SART and other embryo grading systems.

  3. Funding fertility: issues in the allocation and distribution of resources to assisted reproduction technologies.

    PubMed

    Devlin, Nancy; Parkin, David

    2003-05-01

    The appropriate level and source of funds for assisted reproduction technologies (ARTs), in particular IVF, have been controversial in most developed economies. Funding of fertility services internationally is characterized by low public (or other third party) funding, a greater reliance on user-pays than in most other health services, and variations in funding and provision. This article describes the characteristics of infertility as a condition and its treatment that have been used as a rationale for its exclusion from an otherwise comprehensive coverage of health services. The challenges these characteristics pose for the use of economic evaluation to inform resource allocation are discussed. Most economic evaluations have focused on the cost effectiveness of alternative infertility treatments. These evaluations provide important information, but do not inform the real issue at stake: what is the appropriate allocation of funds to ARTs, given that it involves sacrificing improvements in health in other areas? Cost utility analysis - the method of economic appraisal preferred by most agencies charged with making such decisions (including the National Institute of Clinical Excellence in the UK) - is ill-equipped to deal with the benefits produced by ARTs. Alternative methods are available, but require decision makers to weigh up very different sorts of evidence. Demonstration of the willingness to pay for the benefits of ARTs can be used to support public decisions but, conversely, also implies that those who can pay will pay in a private market. Ultimately, decisions about the inclusion or otherwise of ARTs in collectively funded health systems probably rest as much on judgments about equity in access as value for money. Given that this is the case, public funding of IVF should be accompanied by the development of agreed criteria for the prioritization of potential recipients, to ensure treatment is targeted at those for whom it is most effective and that access

  4. Technology complementing military behavioral health efforts at tripler army medical center.

    PubMed

    Stetz, Melba C; Folen, Raymond A; Yamanuha, Bronson K

    2011-06-01

    The purpose of this article is to provide a short narrative on the ways that behavioral health professionals and their patients are currently benefitting from the use of technology. Examples stem from applications of technology to patients/research participants at the Tripler Army Medical Center. The paper also discusses how current use of this technology has made it possible to serve individuals in their own cultural environment, providing a cost-effective means of providing mental health services.

  5. Advanced Measurement Technology at NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    Antcliff, Richard R.

    1998-01-01

    Instrumentation systems have always been essential components of world class wind tunnels and laboratories. Langley continues to be on the forefront of the development of advanced systems for aerospace applications. This paper will describe recent advances in selected measurement systems which have had significant impact on aerospace testing. To fully understand the aerodynamics and aerothermodynamics influencing aerospace vehicles, highly accurate and repeatable measurements need to be made of critical phenomena. However, to maintain leadership in a highly competitive world market, productivity enhancement and the development of new capabilities must also be addressed aggressively. The accomplishment of these sometimes conflicting requirements has been the challenge of advanced measurement developers. However, several new technologies have recently matured to the point where they have enabled the achievement of these goals. One of the critical areas where advanced measurement systems are required is flow field velocity measurements. These measurements are required to correctly characterize the flowfield under study, to quantify the aerodynamic performance of test articles and to assess the effect of aerodynamic vehicles on their environment. Advanced measurement systems are also making great strides in obtaining planar measurements of other important thermodynamic quantities, including species concentration, temperature, pressure and the speed of sound. Langley has been on the forefront of applying these technologies to practical wind tunnel environments. New capabilities in Projection Moire Interferometry and Acoustics Array Measurement systems have extended our capabilities into the model deformation, vibration and noise measurement arenas. An overview of the status of these techniques and recent applications in practical environments will be presented in this paper.

  6. Safety, Reliability, and Quality Assurance Provisions for the Office of Aeronautics, Exploration and Technology Centers

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This Handbook establishes general safety, reliability, and quality assurance (SR&QA) guidelines for use on flight and ground-based projects conducted at the Ames, Langley, and Lewis Research Centers, hereafter identified as the Office of Aeronautics, Exploration and Technology (OAET) Centers. This document is applicable to all projects and operations conducted at these Centers except for those projects covered by more restrictive provisions such as the Space Shuttle, Space Station, and unmanned spacecraft programs. This Handbook is divided into two parts. The first (Chapters 1 and 2) establishes the SR&QA guidelines applicable to the OAET Centers, and the second (Appendices A, B, C, and D) provides examples and definitions for the total SR&QA program. Each center should implement SR&QA programs using these guidelines with tailoring appropriate to the special projects conducted by each Center. This Handbook is issued in loose-leaf form and will be revised by page changes.

  7. The effect of the 2004 Italian law on outcomes of assisted reproduction technology in severe male factor infertility.

    PubMed

    La Sala, G B; Nicoli, A; Capodanno, F; Rondini, I; Villani, M T; Iannotti, F

    2010-01-01

    The Italian law regulating assisted reproductive technologies that came into force in 2004 restricts the number of fertilized oocytes per cycle to three, obliges the subsequent transfer of all resulting embryos and prohibits the freezing of surplus embryos. This study evaluates the impact of the law on severe oligozoospermic, cryptozoospermic, obstructive azoospermic and non-obstructive azoospermic patients. Intracytoplasmic sperm injection outcomes of 1066 cycles performed in the 4years before the passing of the law were compared with 804 cycles performed in the 4years after the law came to pass. Globally, analysis of clinical and obstetric outcomes showed a significant decrease in terms of pregnancy and delivery rates per cycle (17.8% versus 10.9% and 14.2% versus 8.5%, respectively) and per embryo transfer (18.8% versus 13.8% and 15.0% versus 10.7%, respectively), and a significant drop in multiple deliveries (35.1% versus 17.6%) in the post-law period. Cryptozoospermic and azoospermic couples were affected by the Italian law more than severe oligozoospermic couples. The results showed that the Italian law limits the efficiency of assisted reproduction treatment in couples with severe male factor. It is hoped that the Italian assisted reproductive technologies law is altered as soon as possible, allowing the insemination of more than three oocytes.

  8. VACET: Proposed SciDAC2 Visualization and Analytics Center forEnabling Technologies

    SciTech Connect

    Bethel, W.; Johnson, Chris; Hansen, Charles; Parker, Steve; Sanderson, Allen; Silva, Claudio; Tricoche, Xavier; Pascucci, Valerio; Childs, Hank; Cohen, Jonathon; Duchaineau, Mark; Laney, Dan; Lindstrom,Peter; Ahern, Sean; Meredith, Jeremy; Ostrouchov, George; Joy, Ken; Hamann, Bernd

    2006-06-19

    This paper accompanies a poster that is being presented atthe SciDAC 2006 meeting in Denver, CO. This project focuses on leveragingscientific visualization and analytics software technology as an enablingtechnology for increasing scientific productivity and insight. Advancesincomputational technology have resultedin an "information big bang,"which in turn has createda significant data understanding challenge. Thischallenge is widely acknowledged to be one of the primary bottlenecks incontemporary science. The vision for our Center is to respond directly tothat challenge by adapting, extending, creating when necessary anddeploying visualization and data understanding technologies for ourscience stakeholders. Using an organizational model as a Visualizationand Analytics Center for Enabling Technologies (VACET), we are wellpositioned to be responsive to the needs of a diverse set of scientificstakeholders in a coordinated fashion using a range of visualization,mathematics, statistics, computer and computational science and datamanagement technologies.

  9. The feasibility of a unified role for NASA regional dissemination centers and technology application teams

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Insights and recommendations arising from a study of the feasibility of combining the NASA Regional Dissemination Center (RDC) and Technology Application Team (Tateam) roles to form Regional Application Centers (RADC's) are presented. The apparent convergence of the functions of RDC's and Tateams is demonstrated and strongly supportive of the primary recommendation that an applications function be added to those already being performed by the RDC's. The basis of a national network for technology transfer and public and private sector problem solving is shown to exist, the skeleton of which is an interactive network of Regional Application Centers and NASA Field Centers. The feasibility of developing and extending this network is considered and the detailed ramifications of so doing are discussed and the imperatives emphasized. It is hypothesized that such a national network could become relatively independent of NASA funding within five years.

  10. Reproductive Medicine in Amphibians.

    PubMed

    Chai, Norin

    2017-02-04

    Reproduction of amphibians includes ovulation, spermiation, fertilization, oviposition, larval stage and development, and metamorphosis. A problem at any stage could lead to reproductive failure. To stimulate reproduction, environmental conditions must be arranged to simulate changes in natural habits. Reproductive life history is well documented in amphibians; a thorough knowledge of this subject will aid the practitioner in diagnosis and treatment. Technologies for artificial reproduction are developing rapidly, and some protocols may be transferable to privately kept or endangered species. Reproductive tract disorders are rarely described; no bacterial or viral diseases are known that specifically target the amphibian reproductive system.

  11. Mobile STEMship Discovery Center: K-12 Aerospace-Based Science, Technology, Engineering, and Mathematics (STEM) Mobile Teaching Vehicle

    DTIC Science & Technology

    2015-08-03

    AND SUBTITLE Mobile STEMship Discovery Center: K-12 Aerospace-Based Science, Technology, Engineering, and Mathematics (STEM) Mobile Teaching Vehicle...Center program to be able to expose Science Technology, Engineering and Mathematics (STEM) space-inspired science centers for DC Metro beltway schools

  12. 76 FR 2147 - UAW-Chrysler National Training Center Technology Training Joint Programs Staff, Detroit, MI; UAW...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... Employment and Training Administration UAW-Chrysler National Training Center Technology Training Joint Programs Staff, Detroit, MI; UAW-Chrysler Technical Training Center Technology Training Joint Programs... UAW-Chrysler National Training Center, Detroit, ] Michigan (subject firm) to apply for TAA....

  13. NASA Earth Science Mission Control Center Enterprise Emerging Technology Study Study (MCC Technology Study)

    NASA Technical Reports Server (NTRS)

    Smith, Dan; Horan, Stephen; Royer, Don; Sullivan, Don; Moe, Karen

    2015-01-01

    This paper reports on the results of the study to identify technologies that could have a significant impact on Earth Science mission operations when looking out at the 5-15 year horizon (through 2025). The potential benefits of the new technologies will be discussed, as well as recommendations for early research and development, prototyping, or analysis for these technologies.

  14. Assisted Reproductive Technology and Newborn Size in Singletons Resulting from Fresh and Cryopreserved Embryos Transfer

    PubMed Central

    Holzman, Claudia; Zhang, Yujia; Talge, Nicole M.; Li, Chenxi; Todem, David; Boulet, Sheree L.; McKane, Patricia; Kissin, Dmitry M.; Copeland, Glenn; Bernson, Dana; Diamond, Michael P.

    2017-01-01

    Objectives and Study Design The aim of this study was two-fold: to investigate the association of Assisted Reproductive Technology (ART) and small newborn size, using standardized measures; and to examine within strata of fresh and cryopreserved embryos transfer, whether this association is influenced by parental infertility diagnoses. We used a population-based retrospective cohort from Michigan (2000–2009), Florida and Massachusetts (2000–2010). Our sample included 28,946 ART singletons conceived with non-donor oocytes and 4,263,846 non-ART singletons. Methods Regression models were used to examine the association of ART and newborn size, measured as small for gestational age (SGA) and birth-weight-z-score, among four mutually exclusive infertility groups: female infertility only, male infertility only, combined female and male infertility, and unexplained infertility, stratified by fresh and cryopreserved embryos transfer. Results We found increased SGA odds among ART singletons from fresh embryos transfer compared with non-ART singletons, with little difference by infertility source [adjusted odds-ratio for SGA among female infertility only: 1.18 (95% CI 1.10, 1.26), male infertility only: 1.20 (95% CI 1.10, 1.32), male and female infertility: 1.18 (95% CI 1.06, 1.31) and unexplained infertility: 1.24 (95% CI 1.10, 1.38)]. Conversely, ART singletons, born following cryopreserved embryos transfer, had lower SGA odds compared with non-ART singletons, with mild variation by infertility source [adjusted odds-ratio for SGA among female infertility only: 0.56 (95% CI 0.45, 0.71), male infertility only: 0.64 (95% CI 0.47, 0.86), male and female infertility: 0.52 (95% CI 0.36, 0.77) and unexplained infertility: 0.71 (95% CI 0.47, 1.06)]. Birth-weight-z-score was significantly lower for ART singletons born following fresh embryos transfer than non-ART singletons, regardless of infertility diagnoses. PMID:28114395

  15. From biopolitics to bioethics: church, state, medicine and assisted reproductive technology in Ireland.

    PubMed

    McDonnell, Orla; Allison, Jill

    2006-09-01

    This paper examines the emerging bioethical debate on assisted reproductive technology (ART) in Ireland, which is shaped by the long-standing contentious issue of abortion and the constitutional protection afforded to the 'unborn'. The focus of the paper is on the way in which the terms of this debate are shaped and constrained by the historical relations of power between church, state and medicine. Since the representation of Ireland as a post-Catholic, plural republic is becoming increasingly mainstream to cultural and political discourse, we pay particular attention to how the Catholic Church embraces bioethics as a meta frame or code for refocusing questions of values, beliefs and meanings to sustain the ideal of Ireland as a 'pro-life' and essentially Catholic nation. The Catholic Church is not simply asserting its voice of dissent in the context of public debate as one voice amongst a plurality of other voices, but to shape the emerging debate as a powerful, institutional actor. The opportunity to do so is afforded by the lack of public debate on bioethical issues and the exceedingly slow pace at which bioethics is moving towards an institutionalised framework in Ireland. These events can be explained by the legacy of the social power of the Catholic Church in Ireland and the direct and indirect influence it has long exercised over public policy vis-à-vis the state and its institutions, including medicine. There are two interconnected threads to the contextual analysis presented in our case study: first, the legacy of the social power wielded by the Catholic Church, and its slow and incremental demise reflected in the pace of secularisation in Ireland and the privatisation of morality; second, the emergence of a bioethical regulatory debate on ART, which is mired in the abortion controversy. Our analysis focuses on a number of key contradictions and tensions in the way in which the key institutions of church, state and medicine navigate their own positions

  16. SciDAC Visualization and Analytics Center for EnablingTechnology

    SciTech Connect

    Bethel, E. Wes; Johnson, Chris; Joy, Ken; Ahern, Sean; Pascucci,Valerio; Childs, Hank; Cohen, Jonathan; Duchaineau, Mark; Hamann, Bernd; Hansen, Charles; Laney, Dan; Lindstrom, Peter; Meredith, Jeremy; Ostrouchov, George; Parker, Steven; Silva, Claudio; Sanderson, Allen; Tricoche, Xavier

    2006-11-28

    The SciDAC2 Visualization and Analytics Center for EnablingTechnologies (VACET) began operation on 10/1/2006. This document, dated11/27/2006, is the first version of the VACET project management plan. Itwas requested by and delivered to ASCR/DOE. It outlines the Center'saccomplishments in the first six weeks of operation along with broadobjectives for the upcoming future (12-24 months).

  17. A regional technology transfer program. [North Carolina Industrial Applications Center for the Southeast

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The proliferation of online searching capabilities among its industrial clients, changes in marketing staff and direction, use of Dun and Bradstreet marketing service files, growth of the Annual Service Package program, and services delivered to clients at the NASA funded North Carolina Science and Technology Research Center are described. The library search service was reactivated and enlarged, and a survey was conducted on the NC/STRC Technical Bulletin's effectiveness. Several quotations from clients assess the overall value of the Center's services.

  18. Technology Assessment: NREL Provides Know-How for Highly Energy-Efficient Data Centers (Fact Sheet)

    SciTech Connect

    Not Available

    2012-05-01

    NREL leads the effort to change how energy is used worldwide by helping identify and eliminate barriers to energy efficiency and clean energy technology deployment. The laboratory takes a portfolio approach that explores the full range of technology options for developing and implementing innovative energy performance solutions. The Research Support Facility (RSF) data center is a prime example of NREL's capabilities and expertise in energy efficiency. But, more important, its features can be replicated. NREL provides custom technical assistance and training for improved data center performance to help our customers realize cost savings.

  19. Health information technologies for sexual and reproductive health: Mapping the evidence in Latin America and the Caribbean.

    PubMed

    Nigenda, G; Torres, M; Jáuregui, A; Silverman-Retana, J O; Casas, A; Servan-Mori, E

    2016-11-01

    In Latin America and the Caribbean (LAC), the sexual and reproductive health (SRH) of populations is a high priority for governments. Health information technologies (HITs) have been proposed as tools to close access gaps for SRH services. We developed an "evidence map" through a systematic search of articles published between 2005 and 2015 about the use of HITs to enhance SRH services in LAC countries. Two hundred and thirty-two registries were identified and screened. Thirty-one were eligible for full-text assessment. Most of the documents retrieved correspond to information provided by technology developers, targeting primarily the prevention of sexually transmitted infections and adolescent health. Although there has been clear progress in the use of HITs for SRH in the region, many institutional and technological challenges persist. Further studies should be carried out to test the beneficial effects of HITs on improving access to SRH services.

  20. The roles and functions of a lunar base Nuclear Technology Center

    NASA Astrophysics Data System (ADS)

    Buden, D.; Angelo, J. A., Jr.

    This paper describes the roles and functions of a special Nuclear Technology Center which is developed as an integral part of a permanent lunar base. Numerous contemporary studies clearly point out that nuclear energy technology will play a major role in any successful lunar/Mars initiative program and in the overall establishment of humanity's solar system civilization. The key role of nuclear energy in the providing power has been recognized. A Nuclear Technology Center developed as part of a permanent lunar base can also help bring about many other nuclear technology applications, such as producing radioisotopes for self-illumination, food preservation, waste sterilization, and medical treatment; providing thermal energy for mining, materials processing and agricultural; and as a source of emergency habitat power. Designing such a center will involve the deployment, operation, servicing and waste product management and disposal of megawatt class reactor power plants. This challenge must be met with a minimum of direct human support at the facility. Furthermore, to support the timely, efficient integration of this Nuclear Technology Center in the evolving lunar base infrastructure, an analog of such a facility will be needed here on Earth.

  1. The roles and functions of a lunar base Nuclear Technology Center

    SciTech Connect

    Buden, D. ); Angelo, J.A. Jr. )

    1991-01-01

    This paper describes the roles and functions of a special Nuclear Technology Center which is developed as an integral part of a permanent lunar base. Numerous contemporary studies clearly point out that nuclear energy technology will play a major role in any successful lunar/Mars initiative program and in the overall establishment of humanity's solar system civilization. The key role of nuclear energy in the providing power has been recognized. A Nuclear Technology Center developed as part of of a permanent lunar base can also help bring about many other nuclear technology applications, such as producing radioisotopes for self-illumination, food preservation, waste sterilization, and medical treatment; providing thermal energy for mining, materials processing and agricultural; and as a source of emergency habitat power. Designing such a center will involve the deployment, operation, servicing and waste product management and disposal of megawatt class reactor power plants. This challenge must be met with a minimum of direct human support at the facility. Furthermore, to support the timely, efficient integration of this Nuclear Technology Center in the evolving lunar base infrastructure, an analog of such a facility will be needed here on Earth. 12 refs., 4 figs., 1 tab.

  2. Patients meet technology: the newest in patient-centered care initiatives.

    PubMed

    Smith, Sherry P; Barefield, Amanda C

    2007-01-01

    In recent years, health care consumers have become increasingly sophisticated in their selection and use of health care services. Empowered initially by the Internet, they are seeking medical information to become better informed as they interact with physicians and other health care providers. This article addresses (1) the new patient-provider relationship with more provider accountability, the impact of Baby Boomers on health care, and the evolving consumer-driven marketplace with emerging patient-centered care; (2) emerging technologies being used to transform the patient experience; (3) how the use of cutting-edge technologies affect the health care consumer; and (4) the future impact of the use of patient-centered technology initiatives on the health care industry. The personal health record is predicted by experts to be the primary technology that will promote advancement of the electronic health record; therefore, this article focuses on patients' use of the personal health record.

  3. Research and Technology 1998 Annual Report of the Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    1998-01-01

    As the NASA Center responsible for preparing and launching space missions, the John F. Kennedy Space Center (KSC) is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the entire KSC team, consisting of Government and contractor personnel, working in partnership with academic institutions and commercial industry. This edition of the KSC Research and Technology 1998 Annual Report covers the efforts of these contributors to the KSC advanced technology development program, as well as our technology transfer activities. The following research areas are covered: Life Sciences; Mechanical Engineering; Environmental Engineering; Advanced Software; Atmospheric Science; Materials Science; Nondestructive Evaluation; Process/Industrial Engineering; Automation and Robotics; and Electronics and Instrumentation.

  4. Creating Interoperable Meshing and Discretization Software: The Terascale Simulation Tools and Technology Center

    SciTech Connect

    Brown, D.; Freitag, L.; Glimm, J.

    2002-03-28

    We present an overview of the technical objectives of the Terascale Simulation Tools and Technologies center. The primary goal of this multi-institution collaboration is to develop technologies that enable application scientists to easily use multiple mesh and discretization strategies within a single simulation on terascale computers. The discussion focuses on our efforts to create interoperable mesh generation tools, high-order discretization techniques, and adaptive meshing strategies.

  5. Final Report for "Center for Technology for Advanced Scientific Component Software"

    SciTech Connect

    Svetlana Shasharina

    2010-12-01

    The goal of the Center for Technology for Advanced Scientific Component Software is to fundamentally changing the way scientific software is developed and used by bringing component-based software development technologies to high-performance scientific and engineering computing. The role of Tech-X work in TASCS project is to provide an outreach to accelerator physics and fusion applications by introducing TASCS tools into applications, testing tools in the applications and modifying the tools to be more usable.

  6. A prediction model for live birth and multiple births within the first three cycles of assisted reproductive technology

    PubMed Central

    Luke, Barbara; Brown, Morton B.; Wantman, Ethan; Stern, Judy E.; Baker, Valerie L.; Widra, Eric; Coddington, Charles C.; Gibbons, William E.; Ball, G. David

    2014-01-01

    Objective To develop a model predictive of live-birth rates (LBR) and multiple birth rates (MBR) for an individual considering assisted reproduction technology (ART) using linked cycles from Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) for 2004–2011. Design Longitudinal cohort. Setting Clinic-based data. Patient(s) 288,161 women with an initial autologous cycle, of whom 89,855 did not become pregnant and had a second autologous cycle and 39,334 did not become pregnant in the first and second cycles and had a third autologous cycle, with an additional 33,598 women who had a cycle using donor oocytes (first donor cycle). Intervention(s) None. Main Outcome Measure(s) LBRs and MBRs modeled by woman’s age, body mass index, gravidity, prior full-term births, infertility diagnoses by oocyte source, fresh embryos transferred, and cycle, using backward-stepping logistic regression with results presented as adjusted odds ratios (AORs) and 95% confidence intervals. Result(s) The LBRs increased in all models with prior full-term births, number of embryos transferred; in autologous cycles also with gravidity, diagnoses of male factor, and ovulation disorders; and in donor cycles also with the diagnosis of diminished ovarian reserve. The MBR increased in all models with number of embryos transferred and in donor cycles also with prior full-term births. For both autologous and donor cycles, transferring two versus one embryo greatly increased the probability of a multiple birth (AOR 27.25 and 38.90, respectively). Conclusion(s) This validated predictive model will be implemented on the Society for Assisted Reproductive Technology Web site (www.sart.org) so that patients considering initiating a course of ART can input their data on the Web site to generate their expected outcomes. PMID:24934487

  7. Application of video recording technology to improve husbandry and reproduction in the carmine bee-eater (Merops n. nubicus).

    PubMed

    Ferrie, Gina M; Sky, Christy; Schutz, Paul J; Quinones, Glorieli; Breeding, Shawnlei; Plasse, Chelle; Leighty, Katherine A; Bettinger, Tammie L

    2016-01-01

    Incorporating technology with research is becoming increasingly important to enhance animal welfare in zoological settings. Video technology is used in the management of avian populations to facilitate efficient information collection on aspects of avian reproduction that are impractical or impossible to obtain through direct observation. Disney's Animal Kingdom(®) maintains a successful breeding colony of Northern carmine bee-eaters. This African species is a cavity nester, making their nesting behavior difficult to study and manage in an ex situ setting. After initial research focused on developing a suitable nesting environment, our goal was to continue developing methods to improve reproductive success and increase likelihood of chicks fledging. We installed infrared bullet cameras in five nest boxes and connected them to a digital video recording system, with data recorded continuously through the breeding season. We then scored and summarized nesting behaviors. Using remote video methods of observation provided much insight into the behavior of the birds in the colony's nest boxes. We observed aggression between birds during the egg-laying period, and therefore immediately removed all of the eggs for artificial incubation which completely eliminated egg breakage. We also used observations of adult feeding behavior to refine chick hand-rearing diet and practices. Although many video recording configurations have been summarized and evaluated in various reviews, we found success with the digital video recorder and infrared cameras described here. Applying emerging technologies to cavity nesting avian species is a necessary addition to improving management in and sustainability of zoo avian populations.

  8. Development of a National Center for Hydrogen Technology. A Summary Report of Activities Completed at the National Center for Hydrogen Technology - Year 6

    SciTech Connect

    Holmes, Michael

    2012-08-01

    The Energy & Environmental Research Center (EERC) located in Grand Forks, North Dakota, has operated the National Center for Hydrogen Technology (NCHT) since 2005 under a Cooperative Agreement with the U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL). The EERC has a long history of hydrogen generation and utilization from fossil fuels, and under the NCHT Program, the EERC has accelerated its research on hydrogen generation and utilization topics. Since the NCHT's inception, the EERC has received more than $65 million in funding for hydrogen-related projects ($24 million for projects in the NCHT, which includes federal and corporate partner development funds) involving more than 85 partners (27 with the NCHT). The NCHT Program's nine activities span a broad range of technologies that align well with the Advanced Fuels Program goals and, specifically, those described in the Hydrogen from Coal Program research, development, and demonstration (RD&D) plan that refers to realistic testing of technologies at adequate scale, process intensification, and contaminant control. A number of projects have been completed that range from technical feasibility of several hydrogen generation and utilization technologies to public and technical education and outreach tools. Projects under the NCHT have produced hydrogen from natural gas, coal, liquid hydrocarbons, and biomass. The hydrogen or syngas generated by these processes has also been purified in many of these instances or burned directly for power generation. Also, several activities are still undergoing research, development, demonstration, and commercialization at the NCHT. This report provides a summary overview of the projects completed in Year 6 of the NCHT. Individual activity reports are referenced as a source of detailed information on each activity.

  9. The development and technology transfer of software engineering technology at NASA. Johnson Space Center

    NASA Technical Reports Server (NTRS)

    Pitman, C. L.; Erb, D. M.; Izygon, M. E.; Fridge, E. M., III; Roush, G. B.; Braley, D. M.; Savely, R. T.

    1992-01-01

    The United State's big space projects of the next decades, such as Space Station and the Human Exploration Initiative, will need the development of many millions of lines of mission critical software. NASA-Johnson (JSC) is identifying and developing some of the Computer Aided Software Engineering (CASE) technology that NASA will need to build these future software systems. The goal is to improve the quality and the productivity of large software development projects. New trends are outlined in CASE technology and how the Software Technology Branch (STB) at JSC is endeavoring to provide some of these CASE solutions for NASA is described. Key software technology components include knowledge-based systems, software reusability, user interface technology, reengineering environments, management systems for the software development process, software cost models, repository technology, and open, integrated CASE environment frameworks. The paper presents the status and long-term expectations for CASE products. The STB's Reengineering Application Project (REAP), Advanced Software Development Workstation (ASDW) project, and software development cost model (COSTMODL) project are then discussed. Some of the general difficulties of technology transfer are introduced, and a process developed by STB for CASE technology insertion is described.

  10. NASA Lewis Research Center low-gravity fluid management technology program

    NASA Technical Reports Server (NTRS)

    Aydelott, J. C.; Carney, M. J.; Hochstein, J. I.

    1985-01-01

    A history of the Lewis Research Center in space fluid management technology program is presented. Current programs which include numerical modeling of fluid systems, heat exchanger/radiator concept studies, and the design of the Cryogenic Fluid Management Facility are discussed. Recent analytical and experimental activities performed to support the Shuttle/Centaur development activity are highlighted.

  11. Space Science Research and Technology at NASA's Marshall Space Flight Center

    NASA Technical Reports Server (NTRS)

    Johnson, Charles L.

    2007-01-01

    This presentation will summarize the various projects and programs managed in the Space Science Programs and Projects Office at NASA's Marshall Space Flight Center in Huntsville, Alabama. Projects in the portfolio include NASA's Chandra X-Ray telescope, Hinode solar physics satellite, various advanced space propulsion technologies, including solar sails and tethers, as well as NASA's Discovery and New Frontiers Programs.

  12. Investigation of the Feasibility of Establishing Health Technology Demonstration Centers. Final Report.

    ERIC Educational Resources Information Center

    Kahler, Carol

    This investigation studied the feasibility of establishing a network of centers to demonstrate model programs in the health technologies. It was necessary to: 1)identify colleges with multiple health-related programs; 2) identify campus health-related programs which have recognizable strengths; 3)further define "recognizable strengths" through…

  13. Selected Topics in Overset Technology Development and Applications At NASA Ames Research Center

    NASA Technical Reports Server (NTRS)

    Chan, William M.; Kwak, Dochan (Technical Monitor)

    2002-01-01

    This paper presents a general overview of overset technology development and applications at NASA Ames Research Center. The topics include: 1) Overview of overset activities at NASA Ames; 2) Recent developments in Chimera Grid Tools; 3) A general framework for multiple component dynamics; 4) A general script module for automating liquid rocket sub-systems simulations; and 5) Critical future work.

  14. Examining Health Information Technology Implementations: Case of the Patient-Centered Medical Home

    ERIC Educational Resources Information Center

    Behkami, Nima A.

    2012-01-01

    It has been shown that the use of Health Information Technology (HIT) is associated with reduced cost and increased quality of care. This dissertation examined the use of registries in Patient Centered Medical Home (PCMH) practices. A survey questionnaire was sent to a nationwide group of clinics certified for being a PCMH. They were asked to…

  15. Research and technology activities at Ames Research Center's Biomedical Research Division

    NASA Technical Reports Server (NTRS)

    Martello, N.

    1985-01-01

    Various research and technology activities at Ames Research Center's Biomedical Research Division are described. Contributions to the Space Administration's goals in the life sciences include descriptions of research in operational medicine, cardiovascular deconditioning, motion sickness, bone alterations, muscle atrophy, fluid and electrolyte changes, radiation effects and protection, behavior and performance, gravitational biology, and life sciences flight experiments.

  16. Military aircraft and missile technology at the Langley Research Center: A selected bibliography

    NASA Technical Reports Server (NTRS)

    Maddalon, D. V.

    1980-01-01

    A compilation of reference material is presented on the Langley Research Center's efforts in developing advanced military aircraft and missile technology over the past twenty years. Reference material includes research made in aerodynamics, performance, stability, control, stall-spin, propulsion integration, flutter, materials, and structures.

  17. Solid State Technology Branch of NASA Lewis Research Center: Fifth Annual Digest

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The digest is a collection of papers written by the members of the Solid State Technology Branch of NASA Lewis Research Center from June 1992-June 1993. The papers cover a range of topics relating to superconductivity, monolithic microwave integrated circuits (MMIC's), coplanar waveguide, and material characterization.

  18. Community College Advanced Technology Centers: Meeting America's Need for Integrated, Comprehensive Economic Development.

    ERIC Educational Resources Information Center

    Hinckley, Richard; And Others

    By entering into partnerships with business and industry, community colleges are able to offset the high cost of remaining current with training techniques, job market skill requirements, and state-of-the-art hardware. The construction of advanced technology centers (ATCs) located on community college campuses is one key element supporting these…

  19. The New Media Centers' Consortium: A Tool for Legitimizing Technology in Higher Education.

    ERIC Educational Resources Information Center

    Moore, David Richard; Burton, John K.

    1998-01-01

    Reports on part of an ethnographic study of one facility associated with the New Media Centers' Consortium, focusing on the viewpoint of university administration. Suggests the facility was used as a tool for change. Argues for evaluating the role of technology in higher education and for developing an understanding of how its role is legitimized.…

  20. Calcined Waste Storage at the Idaho Nuclear Technology and Engineering Center

    SciTech Connect

    M. D. Staiger M. C. Swenson

    2007-06-01

    This report provides a quantitative inventory and composition (chemical and radioactivity) of calcined waste stored at the Idaho Nuclear Technology and Engineering Center. From December 1963 through May 2000, liquid radioactive wastes generated by spent nuclear fuel reprocessing were converted into a solid, granular form called calcine. This report also contains a description of the calcine storage bins.

  1. Technology Can Help Young Children Succeed. PACER Center ACTion Information Sheets: PHP-c70

    ERIC Educational Resources Information Center

    PACER Center, 2014

    2014-01-01

    Parents of young children with disabilities are discovering that carefully selected computer software and mobile apps can provide many benefits such as improved self-esteem, a longer attention span, and inclusion among family and other children that help their children succeed at home and in school. PACER's Simon Technology Center (STC) can help…

  2. 76 FR 11498 - Submission for OMB Review; Comment Request; Generic Submission of Technology Transfer Center (TTC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... Submission of Technology Transfer Center (TTC) External Customer Satisfaction Surveys (NCI) SUMMARY: Under...) External Customer Satisfaction Surveys (NCI). Type of Information Collection Request: New. Need and Use of Information Collection: The purpose of these web-based surveys are to: obtain information on the...

  3. Mobilizing Learning Resources in a Transnational Classroom: Translocal and Digital Resources in a Community Technology Center

    ERIC Educational Resources Information Center

    Noguerón-Liu, Silvia

    2014-01-01

    Drawing from transnational and activity theory frameworks, this study analyzes the ways translocal flows shape learning in a community technology center serving adult immigrants in the US Southwest. It also explores students' constructions of the transnational nature of the courses they took, where they had access to both online and face-to-face…

  4. Standards, Firewalls, and General Classroom Mayhem: Implementing Student-Centered Technology Projects in the Elementary Classroom

    ERIC Educational Resources Information Center

    Hofer, Mark; Swan, Kathleen Owings

    2006-01-01

    Educators are simultaneously bombarded with both calls to integrate technology in meaningful ways into their teaching and to promote more student-centered activities which combine both content learning and higher-order thinking. This is no small task given the range of student abilities and interests, the increasing emphasis on state standards and…

  5. National Energy Research Scientific Computing Center (NERSC): Advancing the frontiers of computational science and technology

    SciTech Connect

    Hules, J.

    1996-11-01

    National Energy Research Scientific Computing Center (NERSC) provides researchers with high-performance computing tools to tackle science`s biggest and most challenging problems. Founded in 1974 by DOE/ER, the Controlled Thermonuclear Research Computer Center was the first unclassified supercomputer center and was the model for those that followed. Over the years the center`s name was changed to the National Magnetic Fusion Energy Computer Center and then to NERSC; it was relocated to LBNL. NERSC, one of the largest unclassified scientific computing resources in the world, is the principal provider of general-purpose computing services to DOE/ER programs: Magnetic Fusion Energy, High Energy and Nuclear Physics, Basic Energy Sciences, Health and Environmental Research, and the Office of Computational and Technology Research. NERSC users are a diverse community located throughout US and in several foreign countries. This brochure describes: the NERSC advantage, its computational resources and services, future technologies, scientific resources, and computational science of scale (interdisciplinary research over a decade or longer; examples: combustion in engines, waste management chemistry, global climate change modeling).

  6. Idaho Nuclear Technology and Engineering Center Low-Activity Waste Process Technology Program FY-99 Status Report

    SciTech Connect

    A. K. Herbst; J. A. McCray; R. J. Kirkham; J. Pao; S. H. Hinckley

    1999-09-30

    The Low-Activity Waste Process Technology Program at the Idaho Nuclear Technology and Engineering Center (INTEC) anticipates that large volumes of low-level/low-activity wastes will need to be grouted prior to near-surface disposal. During fiscal year 1999, grout formulations were studied for transuranic waste derived from INTEC liquid sodium-bearing waste and for projected newly generated low-level liquid waste. Additional studies were completed on radionuclide leaching, microbial degradation, waste neutralization, and a small mockup for grouting the INTEC underground storage tank residual heels.

  7. Idaho Nuclear Technology and Engineering Center Low-Activity Waste Process Technology Program FY-99 Status Report

    SciTech Connect

    Herbst, Alan Keith; Mc Cray, John Alan; Kirkham, Robert John; Pao, Jenn Hai; Hinckley, Steve Harold

    1999-10-01

    The Low-Activity Waste Process Technology Program at the Idaho Nuclear Technology and Engineering Center (INTEC) anticipates that large volumes of low-level/low-activity wastes will need to be grouted prior to near-surface disposal. During fiscal year 1999, grout formulations were studied for transuranic waste derived from INTEC liquid sodium-bearing waste and for projected newly generated low-level liquid waste. Additional studies were completed on radionuclide leaching, microbial degradation, waste neutralization, and a small mockup for grouting the INTEC underground storage tank residual heels.

  8. Technology utilization in a non-urban region: Further impact and technique of the Technology Use Studies Center, 2

    NASA Technical Reports Server (NTRS)

    Gold, H. C. (Editor); Moore, A. M.; Dodd, B.; Dittmar, V.

    1971-01-01

    The clientele served by the Technology Use Studies Center (TUSC) is updated. Manufacturing leads the list of client firms. The standard industrial classification (SIC) range of these firms is broad. Substantial numbers of college and university faculties are using TUSC services. Field operations inherent in the functions of dissemination and assistance are reviewed. Increasing emphasis among clientele is on environmental concerns and management. A record is provided of the institutions contacted and the extent of TUSC involvement with them, as well as TUSC's cooperation with agencies and organizations. The impact of TUSC and the NASA-sponsored Technology Utilization Program on other public agencies is discussed.

  9. Idaho Nuclear Technology and Engineering Center Low-Activity Waste Process Technology Program FY-98 Status Report

    SciTech Connect

    Herbst, A.K.; McCray, J.A.; Rogers, A.Z.; Simmons, R.F.; Palethrope, S.J.

    1999-03-01

    The Low-Activity Waste Process Technology Program at the Idaho Nuclear Technology and Engineering Center (INTEC) anticipates that large volumes of low-level/low-activity wastes will need to be grouted prior to near-surface disposal. During fiscal year 1998, three grout formulations were studied for low-activity wastes derived from INTEC liquid sodium-bearing waste. Compressive strength and leach results are presented for phosphate bonding cement, acidic grout, and alkaline grout formulations. In an additional study, grout formulations are recommended for stabilization of the INTEC underground storage tank residual heels.

  10. Idaho Nuclear Technology and Engineering Center Low-Activity Waste Process Technology Program, FY-98 Status Report

    SciTech Connect

    Herbst, A.K.; Rogers, A.Z.; McCray, J.A.; Simmons, R.F.; Palethorpe, S.J.

    1999-03-01

    The Low-Activity Waste Process Technology Program at the Idaho Nuclear Technology and Engineering Center (INTEC) anticipates that large volumes of low-level/low-activity wastes will need to be grouted prior to near-surface disposal. During fiscal year 1998, three grout formulations were studied for low-activity wastes derived from INTEC liquid sodium-bearing waste. Compressive strength and leach results are presented for phosphate bonding cement, acidic grout, and alkaline grout formulations. In an additional study, grout formulations are recommended for stabilization of the INTEC underground storage tank residual heels.

  11. Idaho Nuclear Technology and Engineering Center Low-Activity Waste Process Technology Program FY-2000 Status Report

    SciTech Connect

    Herbst, A.K.; McCray, J.A.; Kirkham, R.J.; Pao, J.; Argyle, M.D.; Lauerhass, L.; Bendixsen, C.L.; Hinckley, S.H.

    2000-10-31

    The Low-Activity Waste Process Technology Program anticipated that grouting will be used for disposal of low-level and transuranic wastes generated at the Idaho Nuclear Technology Engineering Center (INTEC). During fiscal year 2000, grout formulations were studied for transuranic waste derived from INTEC liquid sodium-bearing waste and for projected newly generated low-level liquid waste. Additional studies were completed using silica gel and other absorbents to solidify sodium-bearing wastes. A feasibility study and conceptual design were completed for the construction of a grout pilot plant for simulated wastes and demonstration facility for actual wastes.

  12. Idaho Nuclear Technology and Engineering Center Low-Activity Waste Process Technology Program FY-2000 Status Report

    SciTech Connect

    Herbst, Alan Keith; Mc Cray, John Alan; Kirkham, Robert John; Pao, Jenn Hai; Argyle, Mark Don; Lauerhass, Lance; Bendixsen, Carl Lee; Hinckley, Steve Harold

    2000-11-01

    The Low-Activity Waste Process Technology Program anticipated that grouting will be used for disposal of low-level and transuranic wastes generated at the Idaho Nuclear Technology Engineering Center (INTEC). During fiscal year 2000, grout formulations were studied for transuranic waste derived from INTEC liquid sodium-bearing waste and for projected newly generated low-level liquid waste. Additional studies were completed using silica gel and other absorbents to solidify sodium-bearing wastes. A feasibility study and conceptual design were completed for the construction of a grout pilot plant for simulated wastes and demonstration facility for actual wastes.

  13. Development of a national center for hydrogen technology. A summary report of activities completed at the national center hydrogen technology from 2005 to 2010

    SciTech Connect

    Holmes, Michael J.

    2011-06-01

    The Energy & Environmental Research Center (EERC) located in Grand Forks, North Dakota, has operated the National Center for Hydrogen Technology® (NCHT®) since 2005 under a Cooperative Agreement with the U.S. Department of Energy's (DOE) National Energy Technology Laboratory (NETL). The EERC has a long history of hydrogen generation and utilization from fossil fuels, and under the NCHT Program, the EERC has accelerated its research of hydrogen generation and utilization topics. Since the NCHT's inception, the EERC has received more than $65 million in funding of hydrogen-related projects ($20 million for the NCHT project which includes federal and corporate development partner funds) involving more than 85 partners (27 with the NCHT). The NCHT project's 19 activities span a broad range of technologies that align well with the Advanced Fuels Program goals and, specifically, those described in the Hydrogen from Coal Program research, development, and demonstration (RD&D) plan. A number of projects have been completed which range from technical feasibility of several hydrogen generation and utilization technologies to public and technical education and outreach tools. Projects under the NCHT have produced hydrogen from natural gas, coal, liquid hydrocarbons, and biomass. The hydrogen or syngas generated by these processes has also been purified to transportation-grade quality in many of these instances or burned directly for power generation. Also, several activities are still undergoing research, development, demonstration, and commercialization at the NCHT. This report provides a summary overview of the projects completed in the first 5 years of the NCHT. Individual activity reports are referenced as a source of detailed information on each activity.

  14. Review of ultra-high density optical storage technologies for big data center

    NASA Astrophysics Data System (ADS)

    Hao, Ruan; Liu, Jie

    2016-10-01

    In big data center, optical storage technologies have many advantages, such as energy saving and long lifetime. However, how to improve the storage density of optical storage is still a huge challenge. Maybe the multilayer optical storage technology is the good candidate for big data center in the years to come. Due to the number of layers is primarily limited by transmission of each layer, the largest capacities of the multilayer disc are around 1 TB/disc and 10 TB/ cartridge. Holographic data storage (HDS) is a volumetric approach, but its storage capacity is also strictly limited by the diffractive nature of light. For a holographic disc with total thickness of 1.5mm, its potential capacities are not more than 4TB/disc and 40TB/ cartridge. In recent years, the development of super resolution optical storage technology has attracted more attentions. Super-resolution photoinduction-inhibition nanolithography (SPIN) technology with 9 nm feature size and 52nm two-line resolution was reported 3 years ago. However, turning this exciting principle into a real storage system is a huge challenge. It can be expected that in the future, the capacities of 10TB/disc and 100TB/cartridge can be achieved. More importantly, due to breaking the diffraction limit of light, SPIN technology will open the door to improve the optical storage capacity steadily to meet the need of the developing big data center.

  15. Canada's Assisted Human Reproductive Act: is it scientific censorship, or a reasoned approach to the regulation of rapidly emerging reproductive technologies?

    PubMed

    Rasmussen, Colin

    2004-01-01

    After more than a decade of study, discussion and debate, the Canadian House of Commons and Senate have approved the Assisted Human Reproduction Act. Building on the earlier Bill C-47, which died on the order paper in 1997, the Act bans human cloning for reproductive or therapeutic purposes, payment for surrogacy arrangements, and trading in human reproductive materials or their use without informed consent. In addition, the Act significantly restricts research using human reproductive materials. This article compares the Act to legislative regimes in other nations with advanced human reproductive science. It concludes that while the Act has many laudable goals, it is flawed in that it tries to cover too much legislative ground. As a result it unreasonable impairs the ability of Canadian scientists to compete in areas such as stem cell research, and area that is expected to yield significant new approaches to treating human disease.

  16. The Earth System Grid Center for Enabling Technologies: Focusing Technologies on Climate Datasets and Resource Needs

    SciTech Connect

    Williams, Dean N.

    2007-09-26

    This report discusses a project that used prototyping technology to access and analyze climate data. This project was initially funded under the DOE’s Next Generation Internet (NGI) program, with follow-on support from BER and the Mathematical, Information, and Computational Sciences (MICS) office. In this prototype, we developed Data Grid technologies for managing the movement and replication of large datasets, and applied these technologies in a practical setting (i.e., an ESG-enabled data browser based on current climate data analysis tools), achieving cross-country transfer rates of more than 500 Mb/s. Having demonstrated the potential for remotely accessing and analyzing climate data located at sites across the U.S., we won the “Hottest Infrastructure” award in the Network Challenge event. While the ESG I prototype project substantiated a proof of concept (“Turning Climate Datasets into Community Resources”), the SciDAC Earth System Grid (ESG) II project made this a reality. Our efforts targeted the development of metadata technologies (standard schema, XML metadata extraction based on netCDF, and a Metadata Catalog Service), security technologies (Web-based user registration and authentication, and community authorization), data transport technologies (GridFTPenabled OPeNDAP-G for high-performance access, robust multiple file transport and integration with mass storage systems, and support for dataset aggregation and subsetting), as well as web portal technologies to provide interactive access to climate data holdings. At this point, the technology was in place and assembled, and ESG II was poised to make a substantial impact on the climate modelling community.

  17. The rehabilitation engineering research center for the advancement of cognitive technologies.

    PubMed

    Heyn, Patricia Cristine; Cassidy, Joy Lucille; Bodine, Cathy

    2015-02-01

    Barring few exceptions, allied health professionals, engineers, manufacturers of assistive technologies (ATs), and consumer product manufacturers have developed few technologies for individuals with cognitive impairments (CIs). In 2004, the National Institute on Disability Rehabilitation Research (NIDRR) recognized the need to support research in this emergent field. They funded the first Rehabilitation Engineering Research Center for the Advancement of Cognitive Technologies (RERC-ACT). The RERC-ACT has since designed and evaluated existing and emerging technologies through rigorous research, improving upon existing AT devices, and creating new technologies for individuals with CIs. The RERC-ACT has contributed to the development and testing of AT products that assist persons with CIs to actively engage in tasks of daily living at home, school, work, and in the community. This article highlights the RERC-ACT's engineering development and research projects and discusses how current research may impact the quality of life for an aging population.

  18. Considerations for clinics and practitioners treating foreign patients with assisted reproductive technology: lessons from experiences at Ghent University Hospital, Belgium.

    PubMed

    De Sutter, Petra

    2011-11-01

    Cross-border reproductive care (CBRC) is not a new concept, having been around since the beginning of assisted reproductive technology. Countries having taken the lead in developing new technologies have seen an influx of patients from other countries, because of legal limitations or the unavailability of good-quality care in their home country. This paper describes the experience of the Ghent University Hospital fertility centre with Dutch and French patients and tries to set out standards of care for CBRC patients. Dutch patients usually have longer histories, more complex pathology and are better informed, more outspoken and more financially secure. Thus, the care for these patients is challenging. The standards of care should be the same for local patients and CBRC patients; however, the nature of the complexity of the problems they come with will necessitate more time investment. Experience shows that many patients who have no access to treatment in their own country obtain reasonably good results. Some of them, however, are beyond possible help and these patients need a high standard of psychological care. All should be done to avoid that cross-border patients compromise the local care system. Special arrangements should be taken to manage possible complications following treatment.

  19. A comprehensive method for the conservation of mouse strains combining natural breeding, sperm cryopreservation and assisted reproductive technology.

    PubMed

    Li, Dun-Gao; Zhu, Yan; Li, He-Ping; Chen, Xue-Jin; Jiang, Man-Xi

    2014-05-01

    The maintenance and preservation of strains of mice used in biomedical research presents a unique challenge to individual investigators and research institutions. The goal of this study was to assess a comprehensive system for mouse strain conservation through a combination of natural mating, sperm cryopreservation and assisted reproductive technology. Our strategy was based on the collection and cryopreservation of fresh epididymal sperm from male mice by semi-vasectomy; these mice were then naturally mated for breeding purposes. If no satisfactory results were obtained from natural breeding, then the cryopreserved sperm were used for in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI); resultant embryos were then transferred into pseudopregnant-recipient female mice. Our results show that some semi-vasectomized mouse strains can be conserved by natural breeding, and that sterile males can be compensated for through the use of IVF and ICSI technology. As such, we believe this system is suitable for the purpose of strain conservation, allowing the continuation of natural breeding with the safeguard of assisted reproduction available.

  20. Families created by the new reproductive technologies: quality of parenting and social and emotional development of the children.

    PubMed

    Golombok, S; Cook, R; Bish, A; Murray, C

    1995-04-01

    The creation of families by means of the new reproductive technologies has raised important questions about the psychological consequences for children, particularly where gamete donation has been used in the child's conception. Findings are presented of a study of family relationships and the social and emotional development of children in families created as a result of the 2 most widely used reproductive technologies, in vitro fertilization (IVF) and donor insemination (DI), in comparison with control groups of families with a naturally conceived child and adoptive families. The quality of parenting was assessed using a standardized interview with the mother, and mothers and fathers completed questionnaire measures of stress associated with parenting, marital satisfaction, and emotional state. Data on children's psychiatric state were also obtained by standardized interview with the mother, and by questionnaires completed by the mothers and the children's teachers. The children were administered the Separation Anxiety Test, the Family Relations Test, and the Pictorial Scale of Perceived Competence and Social Acceptance. The results showed that the quality of parenting in families with a child conceived by assisted conception is superior to that shown by families with a naturally conceived child. No group differences were found for any of the measures of children's emotions, behavior, or relationships with parents. The findings are discussed in terms of their implications for understanding the role of genetic ties in family functioning and child development.