Sample records for require frequent maintenance

  1. Prosthetic Complications and Maintenance Requirements in Locator-attached Implant-Supported Overdentures: A Retrospective Study.

    PubMed

    Engelhardt, Frank; Zeman, Florian; Behr, Michael; Hahmel, Sebastian

    2016-03-01

    Retrospective data of 32 patients supplied with implant-supported and Locator-attached overdentures were screened for prosthetic complications and maintenance requirements, which were recorded and statistically analyzed. Mean observation time was 4.78 ± 1.72) years. Loss of retention was the most frequently observed event (n = 22). Damage and exchange of the insert holders (n = 4) and loosening of locator attachments (n = 2) and fracture of the insert holder (n = 2) were uncommon events; no loss of locator attachments was observed. Loss of retention in Locator-attached overdentures is frequent; correlating patient-specific parameters with prosthetic complications is necessary to define recommendations for the use of Locator attachments.

  2. Managing Used Oil: Answers to Frequent Questions for Businesses

    EPA Pesticide Factsheets

    Information for businesses such as service stations, fleet maintenance facilities, and quick lube shops that generate and handle used oil. Includes regulatory requirements for storing oil, preventing and managing spills and leaks, and record keeping.

  3. Modeling the response of fracture critical steel box-girder bridges.

    DOT National Transportation Integrated Search

    2010-02-01

    Bridges that are classified as fracture critical by AASHTO require more frequent inspections than other types of : bridges, resulting in greater costs for their maintenance. Several historical events have shown, however, that : severe damage can occu...

  4. BMP FILTERS: UPFLOW VS. DOWNFLOW

    EPA Science Inventory

    Filtration methods have been found to be effective in reducing pollutant levels in stormwater. The main drawback of these methods is that the filters get clogged frequently and require periodical maintenance. In stormwater treatment, because of the cost of pumping, the filters ar...

  5. The Economic Impact of Implementing Nondestructive Testing of Reinforced Concrete Bridge Decks in Indiana

    DOT National Transportation Integrated Search

    2016-08-01

    The deck is among the most expensive components of a bridge over its lifetime because of the frequent and costly maintenance and rehabilitation required. Currently, the Indiana Department of Transportation (INDOT) performs visual inspections of a bri...

  6. Information Measures for Statistical Orbit Determination

    ERIC Educational Resources Information Center

    Mashiku, Alinda K.

    2013-01-01

    The current Situational Space Awareness (SSA) is faced with a huge task of tracking the increasing number of space objects. The tracking of space objects requires frequent and accurate monitoring for orbit maintenance and collision avoidance using methods for statistical orbit determination. Statistical orbit determination enables us to obtain…

  7. External fuel vaporization study, phase 1

    NASA Technical Reports Server (NTRS)

    Szetela, E. J.; Chiappetta, L.

    1980-01-01

    A conceptual design study was conducted to devise and evaluate techniques for the external vaporization of fuel for use in an aircraft gas turbine with characteristics similar to the Energy Efficient Engine (E(3)). Three vaporizer concepts were selected and they were analyzed from the standpoint of fuel thermal stability, integration of the vaporizer system into the aircraft engine, engine and vaporizer dynamic response, startup and altitude restart, engine performance, control requirements, safety, and maintenance. One of the concepts was found to improve the performance of the baseline E(3) engine without seriously compromising engine startup and power change response. Increased maintenance is required because of the need for frequent pyrolytic cleaning of the surfaces in contact with hot fuel.

  8. Maintenance Training Media: An Annotated Bibliography.

    ERIC Educational Resources Information Center

    Valverde, Horace H.

    The training analyst must be able to specify training media requirements during the early stages of weapon systems development. Also, training specialists frequently need to make training media selections for center or base level courses. This report provides such personnel with information to assist them in the development of training equipment…

  9. 12 CFR 704.3 - Corporate credit union capital.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... strategies which provide for the building of capital consistent with regulatory requirements, the maintenance... remains in effect. (8) Adjusted balance accounts: (i) May be adjusted no more frequently than once every... governed by the regulation in effect at the time the paid-in capital was issued. When a grandfathered paid...

  10. Nursing Informatics Competencies: Psychometric Validation, Dissemination, and Maintenance of Self-Assessment Tool for Nurse Leaders.

    PubMed

    Collins, Sarah

    2016-01-01

    Due to rapid advances in technology, HIT competencies for nursing leaders require frequent attention and updating from experts in the field to ensure relevance to nursing leaders' work. This workshop will target nursing informatics researchers and leaders to: 1) learn methods and findings from a study validating a Self-Assessment Scale for Nursing Informatics Competencies for Nurse Leaders, 2) generate awareness of the Self-Assessment scale, 3) discuss strategies for maintenance of competencies overtime and 4) identify strategies to engage nursing leaders in this pursuit.

  11. 14 CFR Appendix E to Part 60 - Qualification Performance Standards for Quality Management Systems for Flight Simulation Training...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... conducted more frequently if warranted. End QPS Requirements Begin Information g. An example of a segment..., scheduling and conducting tests or inspections, functional preflight checks) but retain the responsibility... following: (a) A maintenance facility that provides suitable FSTD hardware and software tests and...

  12. 14 CFR Appendix E to Part 60 - Qualification Performance Standards for Quality Management Systems for Flight Simulation Training...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... conducted more frequently if warranted. End QPS Requirements Begin Information g. An example of a segment..., scheduling and conducting tests or inspections, functional preflight checks) but retain the responsibility... following: (a) A maintenance facility that provides suitable FSTD hardware and software tests and...

  13. Challenges in sensor development for the electric utility industry

    NASA Astrophysics Data System (ADS)

    Ward, Barry H.

    1999-01-01

    The electric utility industry is reducing operating costs in order to prepare for deregulation. The reduction in operating cost has meant a reduction in manpower. The ability to utilize remaining maintenance staff more effectively and to stay competitive in a deregulated environment has therefore become critical. In recent years, the industry has moved away from routine or periodic maintenance to predictive or condition based maintenance. This requires the assessment of equipment condition by frequent testing and inspection; a requirement that is incompatible with cost reduction. To overcome this dilemma, industry trends are toward condition monitoring, whereby the health of apparatus is monitored continuously. This requires the installation of sensors hr transducers on power equipment and the data taken forwarded to an intelligent device for further processing. These devices then analyze the data and make evaluations based on parameter levels or trends, in an attempt to predict possible deterioration. This continuous monitoring allows the electric utility to schedule maintenance on an as needed basis. The industry has been faced with many challenges in sensor design. The measurement of physical, chemical and electrical parameters under extreme conditions of electric fields, magnetic fields, temperature, corrosion, etc. is extensive. This paper will give an overview of these challenges and the solutions adopted for apparatus such as power transformers, circuit breakers, boilers, cables, batteries, and rotating machinery.

  14. Preliminary Design on Screw Press Model of Palm Oil Extraction Machine

    NASA Astrophysics Data System (ADS)

    Firdaus, Muhammad; Salleh, S. M.; Nawi, I.; Ngali, Z.; Siswanto, W. A.; Yusup, E. M.

    2017-01-01

    The concept of the screw press is to compress the fruit bunch between the main screw and travelling cones to extract the palm oil. Visual inspection, model development and simulation of screw press by using Solidworks 2016 and calculation of design properties were performed to support the investigation. The project aims to analyse different design of screw press which improves in reducing maintenance cost and increasing lifespan. The currently existing of screw press can endure between 500 to 900 hours and requires frequent maintenance. Different configurations have been tried in determination of best design properties in screw press. The results specify that screw press with tapered inner shaft has more total lifespan (hours) compared existing screw press. The selection of the screw press with tapered inner shaft can reduce maintenance cost and increase lifespan of the screw press.

  15. Identification of the human factors contributing to maintenance failures in a petroleum operation.

    PubMed

    Antonovsky, Ari; Pollock, Clare; Straker, Leon

    2014-03-01

    This research aimed to identify the most frequently occurring human factors contributing to maintenance-related failures within a petroleum industry organization. Commonality between failures will assist in understanding reliability in maintenance processes, thereby preventing accidents in high-hazard domains. Methods exist for understanding the human factors contributing to accidents. Their application in a maintenance context mainly has been advanced in aviation and nuclear power. Maintenance in the petroleum industry provides a different context for investigating the role that human factors play in influencing outcomes. It is therefore worth investigating the contributing human factors to improve our understanding of both human factors in reliability and the factors specific to this domain. Detailed analyses were conducted of maintenance-related failures (N = 38) in a petroleum company using structured interviews with maintenance technicians. The interview structure was based on the Human Factor Investigation Tool (HFIT), which in turn was based on Rasmussen's model of human malfunction. A mean of 9.5 factors per incident was identified across the cases investigated.The three most frequent human factors contributing to the maintenance failures were found to be assumption (79% of cases), design and maintenance (71%), and communication (66%). HFIT proved to be a useful instrument for identifying the pattern of human factors that recurred most frequently in maintenance-related failures. The high frequency of failures attributed to assumptions and communication demonstrated the importance of problem-solving abilities and organizational communication in a domain where maintenance personnel have a high degree of autonomy and a wide geographical distribution.

  16. Weight maintenance, behaviors and barriers among previous participants of a university-based weight control program.

    PubMed

    Befort, C A; Stewart, E E; Smith, B K; Gibson, C A; Sullivan, D K; Donnelly, J E

    2008-03-01

    To examine weight loss maintenance among previous participants of a university-based behavioral weight management program and to compare behavioral strategies and perceived barriers between successful and unsuccessful maintainers. Previous program participants (n=179) completed mailed surveys assessing current weight, weight control behaviors and perceived barriers to weight loss maintenance. At 14.1+/-10.8 months following completion of treatment, survey respondents were on average 12.6+/-12.6 kg, or 11.3+/-10.7%, below baseline weight; 76.5% of respondents had successfully maintained weight, defined as maintaining a weight loss of at least 5% below baseline. Compared to unsuccessful maintainers, successful maintainers reported practicing four dietary and three physical activity weight control strategies more often and experiencing five barriers to healthy eating and exercise less often. After accounting for time since treatment and maximum weight loss while in treatment, the strongest correlates of successful weight loss maintenance were frequent exercise and perceived difficulty of weight management. Clinically meaningful weight loss maintenance was achieved by the majority of participants. Findings support the literature indicating that physical activity is one of the strongest predictors of successful weight loss maintenance. Findings also suggest that strategies to reduce the level of perceived effort required for long-term weight control may improve maintenance outcomes.

  17. Probabilistic modeling of condition-based maintenance strategies and quantification of its benefits for airliners

    NASA Astrophysics Data System (ADS)

    Pattabhiraman, Sriram

    Airplane fuselage structures are designed with the concept of damage tolerance, wherein small damage are allowed to remain on the airplane, and damage that otherwise affect the safety of the structure are repaired. The damage critical to the safety of the fuselage are repaired by scheduling maintenance at pre-determined intervals. Scheduling maintenance is an interesting trade-off between damage tolerance and cost. Tolerance of larger damage would require less frequent maintenance and hence, a lower cost, to maintain a certain level of reliability. Alternatively, condition-based maintenance techniques have been developed using on-board sensors, which track damage continuously and request maintenance only when the damage size crosses a particular threshold. This effects a tolerance of larger damage than scheduled maintenance, leading to savings in cost. This work quantifies the savings of condition-based maintenance over scheduled maintenance. The work also quantifies converting the cost savings into weight savings. Structural health monitoring will need time to be able to establish itself as a stand-alone system for maintenance, due to concerns on its diagnosis accuracy and reliability. This work also investigates the effect of synchronizing structural health monitoring system with scheduled maintenance. This work uses on-board SHM equipment skip structural airframe maintenance (a subsect of scheduled maintenance), whenever deemed unnecessary while maintain a desired level of safety of structure. The work will also predict the necessary maintenance for a fleet of airplanes, based on the current damage status of the airplanes. The work also analyses the possibility of false alarm, wherein maintenance is being requested with no critical damage on the airplane. The work use SHM as a tool to identify lemons in a fleet of airplanes. Lemons are those airplanes that would warrant more maintenance trips than the average behavior of the fleet.

  18. 49 CFR 37.203 - Lift maintenance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... DISABILITIES (ADA) Over-the-Road Buses (OTRBs) § 37.203 Lift maintenance. (a) The entity shall establish a system of regular and frequent maintenance checks of lifts sufficient to determine if they are operative... 49 Transportation 1 2010-10-01 2010-10-01 false Lift maintenance. 37.203 Section 37.203...

  19. 49 CFR 37.203 - Lift maintenance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Lift maintenance. 37.203 Section 37.203... DISABILITIES (ADA) Over-the-Road Buses (OTRBs) § 37.203 Lift maintenance. (a) The entity shall establish a system of regular and frequent maintenance checks of lifts sufficient to determine if they are operative...

  20. Fatigue risk management in aviation maintenance : current best practices and potential future countermeasures.

    DOT National Transportation Integrated Search

    2011-06-01

    The unregulated hours and frequent night work characteristic of maintenance can produce significant levels of : employee fatigue, with a resultant risk of maintenance error. Fatigue Risk Management Systems (FRMS) are : widely used to manage fatigue a...

  1. Deployable bamboo structure project: A building life-cycle report

    NASA Astrophysics Data System (ADS)

    Firdaus, Adrian; Prastyatama, Budianastas; Sagara, Altho; Wirabuana, Revian N.

    2017-11-01

    Bamboo is considered as a sustainable material in the world of construction, and it is vastly available in Indonesia. The general utilization of the material is increasingly frequent, however, its usage as a deployable structure-a recently-developed use of bamboo, is still untapped. This paper presents a report on a deployable bamboo structure project, covering the entire building life-cycle phase. The cycle encompasses the designing; fabrication; transportation; construction; operation and maintenance; as well as a plan for future re-use. The building is made of a configuration of the structural module, each being a folding set of bars which could be reduced in size to fit into vehicles for easy transportation. Each structural module was made of Gigantochloa apus bamboo. The fabrication, transportation, and construction phase require by a minimum of three workers. The fabrication and construction phase require three hours and fifteen minutes respectively. The building is utilized as cafeteria stands, the operation and maintenance phase started since early March 2017. The maintenance plan is scheduled on a monthly basis, focusing on the inspection of the locking mechanism element and the entire structural integrity. The building is designed to allow disassembly process so that it is reusable in the future.

  2. Discontinuation of Buprenorphine Maintenance Therapy: Perspectives and Outcomes

    PubMed Central

    Bentzley, Brandon S.; Barth, Kelly S.; Back, Sudie E.; Book, Sarah W.

    2015-01-01

    Buprenorphine maintenance therapy (BMT) is increasingly the preferred opioid maintenance agent due to its reduced toxicity and availability in an office-based setting in the United States. Although BMT has been shown to be highly efficacious, it is often discontinued soon after initiation. No current systematic review has yet investigated providers’ or patients’ reasons for BMT discontinuation or the outcomes that follow. Hence, provider and patient perspectives associated with BMT discontinuation after a period of stable buprenorphine maintenance and the resultant outcomes were systematically reviewed with specific emphasis on pre-buprenorphine-taper parameters predictive of relapse following BMT discontinuation. Few identified studies address provider or patient perspectives associated with buprenorphine discontinuation. Within the studies reviewed providers with residency training in BMT were more likely to favor long term BMT instead of detoxification, and providers were likely to consider BMT discontinuation in the face of medication misuse. Patients often desired to remain on BMT because of fear of relapse to illicit opioid use if they were to discontinue BMT. The majority of patients who discontinued BMT did so involuntarily, often due to failure to follow strict program requirements, and 1 month following discontinuation, rates of relapse to illicit opioid use exceeded 50% in every study reviewed. Only lower buprenorphine maintenance dose, which may be a marker for attenuated addiction severity, predicted better outcomes across studies. Relaxed BMT program requirements and frequent counsel on the high probability of relapse if BMT is discontinued may improve retention in treatment and prevent the relapse to illicit opioid use that is likely to follow BMT discontinuation. PMID:25601365

  3. An overview of road damages due to flooding: Case study in Kedah state, Malaysia

    NASA Astrophysics Data System (ADS)

    Ismail, Muhd Shahril Nizam; Ghani, Abdul Naser Abdul

    2017-10-01

    Flooding occurs frequently in many countries including Malaysia. Floods in Malaysia are usually due to heavy and prolonged rainfall, uncontrolled development, and drainage systems that are not being monitored. Road damage due to flooding event can cause huge expenditures for the post-flooding rehabilitation and maintenance. The required maintenance and rehabilitation could upset the original life cycle cost estimations. Data on road statistics were obtained from the Highway Planning Division, Ministry of Works Malaysia and data on flooding was collected from the Department of Irrigation and Drainage Malaysia for events between 2012 and 2015. The pilot sites were selected based on its historical cases of floods that caused road damages in Kedah. The pilot site indicated that the impact of flooding on road infrastructures systems can be used to plan better road design and maintenances. It also revealed that it costs more than RM 1 million to reinstate roads damaged by flooding in a typical district annually.

  4. A gossip based information fusion protocol for distributed frequent itemset mining

    NASA Astrophysics Data System (ADS)

    Sohrabi, Mohammad Karim

    2018-07-01

    The computational complexity, huge memory space requirement, and time-consuming nature of frequent pattern mining process are the most important motivations for distribution and parallelization of this mining process. On the other hand, the emergence of distributed computational and operational environments, which causes the production and maintenance of data on different distributed data sources, makes the parallelization and distribution of the knowledge discovery process inevitable. In this paper, a gossip based distributed itemset mining (GDIM) algorithm is proposed to extract frequent itemsets, which are special types of frequent patterns, in a wireless sensor network environment. In this algorithm, local frequent itemsets of each sensor are extracted using a bit-wise horizontal approach (LHPM) from the nodes which are clustered using a leach-based protocol. Heads of clusters exploit a gossip based protocol in order to communicate each other to find the patterns which their global support is equal to or more than the specified support threshold. Experimental results show that the proposed algorithm outperforms the best existing gossip based algorithm in term of execution time.

  5. Solar energy system performance evaluation: Seasonal report for Decade 80 House, Tucson, Arizona

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The operational and thermal performance of the Decade 80 solar energy system is described. The system was designed by Cooper Development Association, Inc. with space heating and space cooling to a one-story, single family residence located in Tucson, Arizona. The Decade 80 House was designed and built in the mid-70's to be a showplace/workshop for solar energy utilization. Superior construction techniques, the use of quality materials and a full time maintenance staff have served to make the entire system an outstanding example of the application of solar energy for residential purposes. The luxury of a full time, on-site maintenance person is perhaps the single most important aspect of this program. While most installations cannot support this level of maintenance, it was very useful in keeping all subsystems operating in top form and allowing for a full season data collection to be obtained. Several conclusions were drawn from the long term monitoring effort, among which are: (1) flat plate collectors will support cooling; (2) definite energy savings can be realized; and (3) more frequent periodic maintenance may be required on solar energy systems that are not custom built.

  6. Characterization of a Regenerable Impactor Filter for Spacecraft Cabin Applications

    NASA Technical Reports Server (NTRS)

    Agui, Juan H.; Vijayakumar, R.

    2015-01-01

    Regenerable filters will play an important role in human exploration beyond low-Earth orbit. Life Support Systems aboard crewed spacecrafts will have to operate reliably and with little maintenance over periods of more than a year, even multiple years. Air filters are a key component of spacecraft life support systems, but they often require frequent routine maintenance. Bacterial filters aboard the International Space Station require almost weekly cleaning of the pre-filter screen to remove large lint debris captured in the microgravity environment. The source of the airborne matter which is collected on the filter screen is typically from clothing fibers, biological matter (hair, skin, nails, etc.) and material wear. Clearly a need for low maintenance filters requiring little to no crew intervention will be vital to the success of the mission. An impactor filter is being developed and tested to address this need. This filter captures large particle matter through inertial separation and impaction methods on collection surfaces, which can be automatically cleaned after they become heavily loaded. The impactor filter can serve as a pre-filter to augment the life of higher efficiency filters that capture fine and ultrafine particles. A prototype of the filter is being tested at the Particulate Filtration Laboratory at NASA Glenn Research Center to determine performance characteristics, including particle cut size and overall efficiency. Model results are presented for the flow characteristics near the orifice plate through which the particle-laden flow is accelerated as well as around the collection bands.

  7. Preservation of live cultures of basidiomycetes - recent methods.

    PubMed

    Homolka, Ladislav

    2014-02-01

    Basidiomycetes are used in industrial processes, in basic or applied research, teaching, systematic and biodiversity studies. Efficient work with basidiomycete cultures requires their reliable source, which is ensured by their safe long-term storage. Repeated subculturing, frequently used for the preservation, is time-consuming, prone to contamination, and does not prevent genetic and physiological changes during long-term maintenance. Various storage methods have been developed in order to eliminate these disadvantages. Besides lyophilization (unsuitable for the majority of basidiomycetes), cryopreservation at low temperatures seems to be a very efficient way to attain this goal. Besides survival, another requirement for successful maintenance of fungal strains is the ability to preserve their features unchanged. An ideal method has not been created so far. Therefore it is highly desirable to develop new or improve the current preservation methods, combining advantages and eliminate disadvantages of individual techniques. Many reviews on preservation of microorganisms including basidiomycetes have been published, but the progress in the field requires an update. Although herbaria specimens of fungi (and of basidiomycetes in particular) are very important for taxonomic and especially typological studies, this review is limited to live fungal cultures. Copyright © 2013 The British Mycological Society. Published by Elsevier Ltd. All rights reserved.

  8. New control design principles based on measured performance and energy analysis of HVAC (Heating, Ventilating, and Air-Conditioning) systems

    NASA Astrophysics Data System (ADS)

    Hittle, D. C.; Johnson, D. L.

    1985-01-01

    This report is one of a series on the development of heating, ventilating, and air-conditioning (HVAC) control systems that are simple, efficient, reliable, maintainable, and well-documented. This report identifies major problems associated with three currently used HVAC control systems. It also describes the development of a retrofit control system applicable to military buildings that will allow easy identification of component failures, facilitate repair, and minimize system failures. Evaluation of currently used controls showed that pneumatic temperature control equipment requires a very clean source of supply air and is also not very accurate. Pneumatic, rather than electronic, actuators should be used because they are cheaper and require less maintenance. Thermistor temperature detectors should not be used for HVAC applications because they require frequent calibration. It was found that enthalpy economy cycles cannot be used for control because the humidity sensors required for their use are prone to rapid drift, inaccurate, and hard to calibrate in the field. Performance of control systems greatly affects HVAC operating costs. Significant savings can be achieved if proportional-plus-integral control schemes are used. Use of the retrofit prototype control panel developed in this study on variable-air-volume systems should provide significant energy cost savings, improve comfort and reliability, and reduce maintenance costs.

  9. Identification and status of design improvements to the NASA Shuttle EMU for International Space Station application.

    PubMed

    Wilde, R C; McBarron, J W; Faszcza, J J

    1997-06-01

    To meet the significant increase in EVA demand to support assembly and operations of the International Space Station (ISS), NASA and industry have improved the current Shuttle Extravehicular Mobility Unit (EMU), or "space suit", configuration to meet the unique and specific requirements of an orbital-based system. The current Shuttle EMU was designed to be maintained and serviced on the ground between frequent Shuttle flights. ISS will require the EMUs to meet increased EVAs out of the Shuttle Orbiter and to remain on orbit for up to 180 days without need for regular return to Earth for scheduled maintenance or refurbishment. Ongoing Shuttle EMU improvements have increased reliability, operational life and performance while minimizing ground and on-orbit maintenance cost and expendable inventory. Modifications to both the anthropomorphic mobility elements of the Space Suit Assembly (SSA) as well as to the Primary Life Support System (PLSS) are identified and discussed. This paper also addresses the status of on-going Shuttle EMU improvements and summarizes the approach for increasing interoperability of the U.S. and Russian space suits to be utilized aboard the ISS.

  10. Bus Maintenance is a Sound Investment.

    ERIC Educational Resources Information Center

    American School Board Journal, 1981

    1981-01-01

    Preventive school bus maintenance to reduce long-term costs should include daily visual inspections by drivers, frequent checks by mechanics, and comprehensive inspections every 5,000 miles. Mechanics recommend checking tail lights, batteries, brakes, lug nuts, leaf springs, tail pipes, and exhaust pipe hangers. (RW)

  11. Development of a nondestructive evaluation method for FRP bridge decks

    NASA Astrophysics Data System (ADS)

    Brown, Jeff; Fox, Terra

    2010-05-01

    Open steel grids are typically used on bridges to minimize the weight of the bridge deck and wearing surface. These grids, however, require frequent maintenance and exhibit other durability concerns related to fatigue cracking and corrosion. Bridge decks constructed from composite materials, such as a Fiber-reinforced Polymer (FRP), are strong and lightweight; they also offer improved rideability, reduced noise levels, less maintenance, and are relatively easy to install compared to steel grids. This research is aimed at developing an inspection protocol for FRP bridge decks using Infrared thermography. The finite element method was used to simulate the heat transfer process and determine optimal heating and data acquisition parameters that will be used to inspect FRP bridge decks in the field. It was demonstrated that thermal imaging could successfully identify features of the FRP bridge deck to depths of 1.7 cm using a phase analysis process.

  12. Inefficiencies in water project design and operation in the third world: An economic perspective

    NASA Astrophysics Data System (ADS)

    Howe, Charles W.; Dixon, John A.

    1993-07-01

    Water projects in less developed countries (LDCs) frequently are poorly operated and maintained. As a result, project benefits and development impacts fall short of plans. The problems begin in the project identification, design, and construction stages: donor and host country biases lead to inappropriate projects, unsustainable technologies, and shoddy construction. Later operation and maintenance are then difficult or impossible. Causal factors include donor desire to build monuments and sell technology, provision of excessive capital to favored sectors or institutions, and an unwillingness to require a reasonable quid pro quo from the host country. Host country factors include excessive administrative centralization, lack of rewards for good operation and maintenance, and widespread corruption in forms that seriously distort allocative efficiency. Until individual actors on both sides can be motivated to pursue the long-run good of the LDC, Third World water projects will continue to have low or negative net payoffs.

  13. Change Strategies and Associated Implementation Challenges: An Analysis of Online Counselling Sessions.

    PubMed

    Rodda, Simone N; Hing, Nerilee; Hodgins, David C; Cheetham, Alison; Dickins, Marissa; Lubman, Dan I

    2017-09-01

    Self-change is the most frequent way people limit or reduce gambling involvement and often the first choice of people experiencing gambling-related problems. Less well known is the range of change strategies gamblers use and how these are selected, initiated or maintained. This study examined change strategies discussed in counselling transcripts from 149 clients who accessed a national online gambling help service in Australia. Using thematic analysis, we identified the presence of six change strategies; cash control and financial management, social support, avoiding or limiting gambling, alternative activities, changing thoughts and beliefs, and self-assessment and monitoring. Four implementation issues were also identified; a mismatch between need and strategy selection or maintenance; importance and readiness versus the cost of implementation; poor or unplanned transitions between strategies; and failure to review the helpfulness of strategies resulting in premature abandonment or unhelpful prolonged application. This study is the first to identify change strategies discussed in online counselling sessions. This study suggests change strategies are frequently discussed in online counselling sessions and we identified multiple new actions associated with change strategies that had not previously been identified. However, multiple implementation issues were identified and further work is required to determine the helpfulness of change strategies in terms of their selection, initiation and maintenance.

  14. Frequent hemodialysis with NxStage system in pediatric patients receiving maintenance hemodialysis.

    PubMed

    Goldstein, Stuart L; Silverstein, Douglas M; Leung, Jocelyn C; Feig, Daniel I; Soletsky, Beth; Knight, Cathy; Warady, Bradley A

    2008-01-01

    Recent evidence from adult hemodialysis (HD) patient studies reveal improved biochemical control and reported health-related quality of life after transition from conventional thrice weekly to daily home maintenance HD treatment. Published pediatric frequent dialysis experiences demonstrate similar improvement but all used conventional HD machines, which employ a treated municipal water supply, thereby frequently exposing patients to proinflammatory components. We report our pediatric experience with six-times-weekly HD using the NxStage system, which uses sterile dialysis fluid to provide dialysis in the home or center setting. Four patients (weight range 38-61.4 kg) completed the 16-week study. Patients exhibited progressive reductions in casual pretreatment systolic and diastolic blood pressures, discontinuation of antihypertensive medications, and decreased blood pressure load by ambulatory blood pressure monitoring. Mean serum phosphorus improved without change in phosphorus binder medication, and all three patients with a normalized protein catabolic rate <1 g/kg per day at the beginning of the study improved to a normalized protein catabolic rate (nPCR) of >1.1 g/kg per day. Patients reported no adverse effects. Variable changes in proinflammatory cytokine levels were observed. We suggest that frequent HD with the NxStage system be considered for children who would benefit from home-based maintenance dialysis.

  15. 78 FR 72122 - Draft Emergency Preparedness Frequently Asked Questions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0262] Draft Emergency Preparedness Frequently Asked... of guidance documents related to the development and maintenance of emergency preparedness program... the interpretation or applicability of emergency preparedness guidance issued or endorsed by the NRC...

  16. [Medical therapy of inflammatory bowel diseases: ulcerative colitis].

    PubMed

    Lakatos, László; Lakatos, Péter László

    2007-06-24

    There are fewer significant changes in the medical therapy of ulcerative colitis (UC) compared to Crohn's disease. The most important factors that determine therapy are disease extent and severity. 5-aminosalicylates (5-ASA) constitute the treatment of choice in mild-to-moderate UC. The efficacy of new compounds (e.g. mesalazine) is only mildly improved compared to sulphasalazine; however, their use has become more frequent due to a more favorable side effects profile. Topical medication is more effective in proctitis and distal colitis, and the combination of topical and orally-administered drugs is superior to oral therapy alone also in extensive disease. Thus, this latter regimen should be considered for cases where the escalation of treatment is required. Systemic steroids still represent the first line therapy in acute, severe UC, while in patients who do not respond to steroids, cyclosporine and infliximab should be considered as a second line therapy and as alternatives for colectomy. Maintenance treatment is indicated in all UC cases. 5-ASA compounds are suggested as first line maintenance therapy with the optimal dose still being under investigation. Topical compounds are effective also for maintenance in distal colitis or proctitis, if accepted by the patients. Immunosuppressives, especially azathioprine, should be considered in chronically active, steroid dependent or resistant patients. According to recent publications, azathioprine is almost equally effective in UC and CD. The question of chemoprevention is important during maintenance. There are increasing data supporting the notion that aminosalicylates may lower the risk for UC-associated colorectal cancer. The most important changes in the management of UC are the more frequent use of topical aminosalicylates and azathioprine, the availability of infliximab in severe UC, and increasing use of aminosalicylates for chemoprevention of colorectal carcinoma. Furthermore, adequate attention is needed to better organize the patient-doctor relationship and for greater adherence to medical therapy.

  17. Maintenance Energy Requirements of Double-Muscled Belgian Blue Beef Cows

    PubMed Central

    Fiems, Leo O.; De Boever, Johan L.; Vanacker, José M.; De Campeneere, Sam

    2015-01-01

    Simple Summary Double-muscled Belgian Blue animals are extremely lean, characterized by a deviant muscle fiber type with more fast-glycolytic fibers, compared to non-double-muscled animals. This fiber type may result in lower maintenance energy requirements. On the other hand, lean meat animals mostly have a higher rate of protein turnover, which requires more energy for maintenance. Therefore, maintenance requirements of Belgian Blue cows were investigated based on a zero body weight gain. This technique showed that maintenance energy requirements of double-muscled Belgian Blue beef cows were close to the mean requirements of cows of other beef genotypes. Abstract Sixty non-pregnant, non-lactating double-muscled Belgian Blue (DMBB) cows were used to estimate the energy required to maintain body weight (BW). They were fed one of three energy levels for 112 or 140 days, corresponding to approximately 100%, 80% or 70% of their total energy requirements. The relationship between daily energy intake and BW and daily BW change was developed using regression analysis. Maintenance energy requirements were estimated from the regression equation by setting BW gain to zero. Metabolizable and net energy for maintenance amounted to 0.569 ± 0.001 and 0.332 ± 0.001 MJ per kg BW0.75/d, respectively. Maintenance energy requirements were not dependent on energy level (p > 0.10). Parity affected maintenance energy requirements (p < 0.001), although the small numerical differences between parities may hardly be nutritionally relevant. Maintenance energy requirements of DMBB beef cows were close to the mean energy requirements of other beef genotypes reported in the literature. PMID:26479139

  18. Automatically updating predictive modeling workflows support decision-making in drug design.

    PubMed

    Muegge, Ingo; Bentzien, Jörg; Mukherjee, Prasenjit; Hughes, Robert O

    2016-09-01

    Using predictive models for early decision-making in drug discovery has become standard practice. We suggest that model building needs to be automated with minimum input and low technical maintenance requirements. Models perform best when tailored to answering specific compound optimization related questions. If qualitative answers are required, 2-bin classification models are preferred. Integrating predictive modeling results with structural information stimulates better decision making. For in silico models supporting rapid structure-activity relationship cycles the performance deteriorates within weeks. Frequent automated updates of predictive models ensure best predictions. Consensus between multiple modeling approaches increases the prediction confidence. Combining qualified and nonqualified data optimally uses all available information. Dose predictions provide a holistic alternative to multiple individual property predictions for reaching complex decisions.

  19. 40 CFR 63.7745 - How do I demonstrate continuous compliance with the operation and maintenance requirements that...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... compliance with the operation and maintenance requirements that apply to me? 63.7745 Section 63.7745....7745 How do I demonstrate continuous compliance with the operation and maintenance requirements that... maintenance requirements of § 63.7710 by: (1) Making monthly inspections of capture systems and initiating...

  20. 40 CFR 63.9636 - How do I demonstrate continuous compliance with the operation and maintenance requirements that...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... compliance with the operation and maintenance requirements that apply to me? 63.9636 Section 63.9636....9636 How do I demonstrate continuous compliance with the operation and maintenance requirements that... demonstrate continuous compliance with the operation and maintenance requirements in § 63.9600(b) by...

  1. 14 CFR 147.38 - Maintenance of curriculum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (CONTINUED) SCHOOLS AND OTHER CERTIFICATED AGENCIES AVIATION MAINTENANCE TECHNICIAN SCHOOLS Operating Rules § 147.38 Maintenance of curriculum requirements. (a) Each certificated aviation maintenance technician...

  2. 14 CFR 147.38 - Maintenance of curriculum requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Maintenance of curriculum requirements. 147... § 147.38 Maintenance of curriculum requirements. (a) Each certificated aviation maintenance technician school shall adhere to its approved curriculum. With FAA approval, curriculum subjects may be taught at...

  3. 40 CFR 63.105 - Maintenance wastewater requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 10 2012-07-01 2012-07-01 false Maintenance wastewater requirements... Manufacturing Industry § 63.105 Maintenance wastewater requirements. (a) Each owner or operator of a source... for maintenance wastewaters containing those organic HAP's listed in table 9 of subpart G of this part...

  4. The Effects of Beacons, Comments, and Tasks on Program Comprehension Process in Software Maintenance

    ERIC Educational Resources Information Center

    Fan, Quyin

    2010-01-01

    Program comprehension is the most important and frequent process in software maintenance. Extensive research has found that individual characteristics of programmers, differences of computer programs, and differences of task-driven motivations are the major factors that affect the program comprehension results. There is no study specifically…

  5. 40 CFR 63.7826 - How do I demonstrate initial compliance with the operation and maintenance requirements that...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... preventative maintenance schedule and, as applicable, detailed descriptions of the corrective action procedures... compliance with the operation and maintenance requirements that apply to me? 63.7826 Section 63.7826... Compliance Requirements § 63.7826 How do I demonstrate initial compliance with the operation and maintenance...

  6. Efficacy of golimumab on recurrent uveitis in HLA-B27-positive ankylosing spondylitis.

    PubMed

    Yazgan, Serpil; Celik, Ugur; Işık, Metin; Yeşil, Nesibe Karahan; Baki, Ali Erdem; Şahin, Hatice; Gencer, Ercan; Doğan, İsmail

    2017-02-01

    To evaluate the efficacy of golimumab on severe and frequent recurrent anterior uveitis in patients with HLA-B27-positive ankylosing spondylitis. In this study, 15 eyes of 12 HLA-B27-positive AS patients with resistant anterior uveitis who received 50 mg of subcutaneous golimumab (Gol) per month due to frequent uveitis recurrences were analyzed retrospectively between May 2013 and October 2015. Assessment criteria were uveitis activity, the number of recurrence of uveitis, visual acuity, systemic corticosteroid, or other drug requirement for maintenance of remission of AU. Twelve patients (15 eyes) with HLA-B27-positive ankylosing spondylitis and anterior uveitis have been treated with golimumab 50 mg/month. Remission of uveitis was observed in 12 eyes out of 15. Malign hypertension developed in one subject after the second dose of golimumab therefore the treatment was stopped and this subject was excluded from the study. Median follow-up time was 11 months (interquartile range: 8-18). No uveitic reaction was seen except in the patient who stopped treatment. No topical or systemic steroid necessity was needed except in two cases with oral 4 mg systemic maintenance. Visual acuity was significantly increased (p = 0.002). Golimumab may be a new and effective choice for maintaining remission and the prevention of recurrences of severe, resistant anterior uveitis in patients with HLA-B27-positive ankylosing spondylitis.

  7. On-farm estimation of energy balance in dairy cows using only frequent body weight measurements and body condition score.

    PubMed

    Thorup, V M; Edwards, D; Friggens, N C

    2012-04-01

    Precise energy balance estimates for individual cows are of great importance to monitor health, reproduction, and feed management. Energy balance is usually calculated as energy input minus output (EB(inout)), requiring measurements of feed intake and energy output sources (milk, maintenance, activity, growth, and pregnancy). Except for milk yield, direct measurements of the other sources are difficult to obtain in practice, and estimates contain considerable error sources, limiting on-farm use. Alternatively, energy balance can be estimated from body reserve changes (EB(body)) using body weight (BW) and body condition score (BCS). Automated weighing systems exist and new technology performing semi-automated body condition scoring has emerged, so frequent automated BW and BCS measurements are feasible. We present a method to derive individual EB(body) estimates from frequently measured BW and BCS and evaluate the performance of the estimated EB(body) against the traditional EB(inout) method. From 76 Danish Holstein and Jersey cows, parity 1 or 2+, on a glycerol-rich or a whole grain-rich total mixed ration, BW was measured automatically at each milking. The BW was corrected for the weight of milk produced and for gutfill. Changes in BW and BCS were used to calculate changes in body protein, body lipid, and EB(body) during the first 150 d in milk. The EB(body) was compared with the traditional EB(inout) by isolating the term within EB(inout) associated with most uncertainty; that is, feed energy content (FEC); FEC=(EB(body)+EMilk+EMaintenance+Eactivity)/dry matter intake, where the energy requirements are for milk produced (EMilk), maintenance (EMaintenance), and activity (EActivity). Estimated FEC agreed well with FEC values derived from tables (the mean estimate was 0.21 MJ of effective energy/kg of dry matter or 2.2% higher than the mean table value). Further, the FEC profile did not suggest systematic bias in EB(body) with stage of lactation. The EB(body) estimated from daily BW, adjusted for milk and meal-related gutfill and combined with frequent BCS, can provide a successful tool. This offers a pragmatic solution to on-farm calculation of energy balance with the perspective of improved precision under commercial conditions. Copyright © 2012 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  8. Correlates of Successful Response to a Behavioral Weight Control Clinic.

    ERIC Educational Resources Information Center

    And Others; Gormally, Jim

    1980-01-01

    Initial weight-loss success was correlated with two severity variables. Persons reporting frequent binge eating and histories of previous dieting weight loss lost the most weight. Persons who were successful at maintenance used frequent exercise. Those who relapsed reported high levels of stress during follow-up. (Author)

  9. Maintenance Energy Requirements of Double-Muscled Belgian Blue Beef Cows.

    PubMed

    Fiems, Leo O; De Boever, Johan L; Vanacker, José M; De Campeneere, Sam

    2015-02-13

    Sixty non-pregnant, non-lactating double-muscled Belgian Blue (DMBB) cows were used to estimate the energy required to maintain body weight (BW). They were fed one of three energy levels for 112 or 140 days, corresponding to approximately 100%, 80% or 70% of their total energy requirements. The relationship between daily energy intake and BW and daily BW change was developed using regression analysis. Maintenance energy requirements were estimated from the regression equation by setting BW gain to zero. Metabolizable and net energy for maintenance amounted to 0.569 ± 0.001 and 0.332 ± 0.001 MJ per kg BW(0.75)/d, respectively. Maintenance energy requirements were not dependent on energy level (p > 0.10). Parity affected maintenance energy requirements (p < 0.001), although the small numerical differences between parities may hardly be nutritionally relevant. Maintenance energy requirements of DMBB beef cows were close to the mean energy requirements of other beef genotypes reported in the literature.

  10. The maintenance gap: a new theoretical perspective on the evolution of aging.

    PubMed

    Wensink, Maarten J; van Heemst, Diana; Rozing, Maarten P; Westendorp, Rudi G J

    2012-04-01

    One of the prevailing theories of aging, the disposable soma theory, views aging as the result of the accumulation of damage through imperfect maintenance. Aging, then, is explained from an evolutionary perspective by asserting that this lack of maintenance exists because the required resources are better invested in reproduction. However, the amount of maintenance necessary to prevent aging, 'maintenance requirement' has so far been largely neglected and has certainly not been considered from an evolutionary perspective. To our knowledge we are the first to do so, and arrive at the conclusion that all maintenance requirement needs an evolutionary explanation. Increases in maintenance requirement can only be selected for if these are linked with either higher fecundity or better capabilities to cope with environmental challenges to the integrity of the organism. Several observations are suggestive of the latter kind of trade-off, the existence of which leads to the inevitable conclusion that the level of maintenance requirement is in principle unbound. Even the allocation of all available resources to maintenance could be unable to stop aging in some organisms. This has major implications for our understanding of the aging process on both the evolutionary and the mechanistic level. It means that the expected effect of measures to reallocate resources to maintenance from reproduction may be small in some species. We need to have an idea of how much maintenance is necessary in the first place. Our explorations of how natural selection is expected to act on the maintenance requirement provides the first step in understanding this.

  11. 49 CFR 214.511 - Required audible warning devices for new on-track roadway maintenance machines.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... roadway maintenance machines. 214.511 Section 214.511 Transportation Other Regulations Relating to... SAFETY On-Track Roadway Maintenance Machines and Hi-Rail Vehicles § 214.511 Required audible warning devices for new on-track roadway maintenance machines. Each new on-track roadway maintenance machine shall...

  12. 49 CFR 214.511 - Required audible warning devices for new on-track roadway maintenance machines.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... roadway maintenance machines. 214.511 Section 214.511 Transportation Other Regulations Relating to... SAFETY On-Track Roadway Maintenance Machines and Hi-Rail Vehicles § 214.511 Required audible warning devices for new on-track roadway maintenance machines. Each new on-track roadway maintenance machine shall...

  13. Phase 111A Crew Interface Specifications Development for Inflight Maintenance and Stowage Functions

    NASA Technical Reports Server (NTRS)

    Carl, John G.

    1973-01-01

    This report presents the findings and data products developed during the Phase IIIA Crew Interface Specification Study for Inflight Maintenance and Stowage Functions, performed by General Electric for the NASA, Johnson Space Center with a set of documentation that can be used as definitive guidelines to improve the present process of defining, controlling and managing flight crew interface requirements that are related to inflight maintenance (including assembly and servicing) and stowage functions. During the Phase IIIA contract period, the following data products were developed: 1) Projected NASA Crew Procedures/Flight Data File Development Process. 2) Inflight Maintenance Management Process Description. 3) Preliminary Draft, General Specification, Inflight Maintenance Management Requirements. 4) Inflight Maintenance Operational Process Description. 5) Preliminary Draft, General Specification, Inflight Maintenance Task and Support Requirements Analysis. 6) Suggested IFM Data Processing Reports for Logistics Management The above Inflight Maintenance data products have been developed during the Phase IIIA study after review of Space Shuttle Program Documentation, including the Level II Integrated Logistics Requirements and other DOD and NASA data relative to Payloads Accommodations and Satellite On-Orbit Servicing. These Inflight Maintenance data products were developed to be in consonance with Space Shuttle Program technical and management requirements.

  14. Safety, resource use, and quality of life in paramount: a phase III study of maintenance pemetrexed versus placebo after induction pemetrexed plus cisplatin for advanced nonsquamous non-small-cell lung cancer.

    PubMed

    Gridelli, Cesare; de Marinis, Filippo; Pujol, Jean-Louis; Reck, Martin; Ramlau, Rodryg; Parente, Barbara; Pieters, Thierry; Middleton, Gary; Corral, Jesus; Winfree, Katherine; Melemed, Symantha; Zimmermann, Anna; John, William; Beyrer, Julie; Chouaki, Nadia; Visseren-Grul, Carla; Paz-Ares, Luis G

    2012-11-01

    In a phase III, randomized, double-blind study (PARAMOUNT), maintenance pemetrexed demonstrated significant benefit in advanced non-small-cell lung cancer (NSCLC). We present safety, resource use, and quality of life (QoL) results. After four 21-day cycles of pemetrexed-cisplatin (N = 939), patients with advanced nonsquamous NSCLC, whose disease had not progressed and who had a performance status of 0/1, were randomized 2:1 (N = 539) to maintenance pemetrexed 500 mg/m plus best supportive care or placebo plus best supportive care every 21 days until disease progression or unacceptable toxicity. QoL was measured using the EuroQol 5-dimensional questionnaire (EQ-5D). Frequently reported grade 3 to 4 drug-related toxicities with maintenance pemetrexed versus placebo were anemia (4.5% versus 0.6%; p = 0.016), fatigue (4.2% versus 0.6%; p = 0.016), and neutropenia (3.6% versus 0.0%; p < 0.006). No significant differences in drug-related grade 3 to 5 toxicities were observed with long-term pemetrexed exposure (>6 cycles), except grade 3 to 4 neutropenia, which did not result in increased infections. Patients on maintenance pemetrexed required more transfusions (13.4% versus 5.0%; p = 0.003), granulocyte colony- or granulocyte-macrophage colony-stimulating factors (5.3% versus 0.0%; p <0.001), anti-infectives (25.3% versus 16.7%; p = 0.028), and hospitalizations because of study drug (8.4% versus 3.3%, p = 0.028) than placebo-treated patients did. No significant treatment-by-time interactions, overall treatment differences, or clinically relevant changes from baseline were observed in EQ-5D scores during treatment. Long-term use of continuation maintenance pemetrexed was well tolerated; resource use was low, corresponding with known pemetrexed toxicities. The EQ-5D results demonstrate that patients tolerate long-term maintenance pemetrexed without worsening QoL.

  15. Energy requirements of adult dogs: a meta-analysis.

    PubMed

    Bermingham, Emma N; Thomas, David G; Cave, Nicholas J; Morris, Penelope J; Butterwick, Richard F; German, Alexander J

    2014-01-01

    A meta-analysis was conducted to determine the maintenance energy requirements of adult dogs. Suitable publications were first identified, and then used to generate relationships amongst energy requirements, husbandry, activity level, methodology, sex, neuter status, dog size, and age in healthy adult dogs. Allometric equations for maintenance energy requirements were determined using log-log linear regression. So that the resulting equations could readily be compared with equations reported by the National Research Council, maintenance energy requirements in the current study were determined in kcal/kg(0.75) body weight (BW). Ultimately, the data of 70 treatment groups from 29 publications were used, and mean (± standard deviation) maintenance energy requirements were 142.8±55.3 kcal·kgBW(-0.75)·day(-1). The corresponding allometric equation was 81.5 kcal·kgBW(-0.9)·day(-1) (adjusted R2 = 0.64; 70 treatment groups). Type of husbandry had a significant effect on maintenance energy requirements (P<0.001): requirements were greatest in racing dogs, followed by working dogs and hunting dogs, whilst the energy requirements of pet dogs and kennel dogs were least. Maintenance energy requirements were less in neutered compared with sexually intact dogs (P<0.001), but there was no effect of sex. Further, reported activity level tended to effect the maintenance energy requirement of the dog (P = 0.09). This review suggests that estimating maintenance energy requirements based on BW alone may not be accurate, but that predictions that factor in husbandry, neuter status and, possibly, activity level might be superior. Additionally, more information on the nutrient requirements of older dogs, and those at the extremes of body size (i.e. giant and toy breeds) is needed.

  16. Energy Requirements of Adult Dogs: A Meta-Analysis

    PubMed Central

    Bermingham, Emma N.; Thomas, David G.; Cave, Nicholas J.; Morris, Penelope J.; Butterwick, Richard F.; German, Alexander J.

    2014-01-01

    A meta-analysis was conducted to determine the maintenance energy requirements of adult dogs. Suitable publications were first identified, and then used to generate relationships amongst energy requirements, husbandry, activity level, methodology, sex, neuter status, dog size, and age in healthy adult dogs. Allometric equations for maintenance energy requirements were determined using log-log linear regression. So that the resulting equations could readily be compared with equations reported by the National Research Council, maintenance energy requirements in the current study were determined in kcal/kg0.75 body weight (BW). Ultimately, the data of 70 treatment groups from 29 publications were used, and mean (± standard deviation) maintenance energy requirements were 142.8±55.3 kcal.kgBW−0.75.day−1. The corresponding allometric equation was 81.5 kcal.kgBW−0.93.day−1 (adjusted R2 = 0.64; 70 treatment groups). Type of husbandry had a significant effect on maintenance energy requirements (P<0.001): requirements were greatest in racing dogs, followed by working dogs and hunting dogs, whilst the energy requirements of pet dogs and kennel dogs were least. Maintenance energy requirements were less in neutered compared with sexually intact dogs (P<0.001), but there was no effect of sex. Further, reported activity level tended to effect the maintenance energy requirement of the dog (P = 0.09). This review suggests that estimating maintenance energy requirements based on BW alone may not be accurate, but that predictions that factor in husbandry, neuter status and, possibly, activity level might be superior. Additionally, more information on the nutrient requirements of older dogs, and those at the extremes of body size (i.e. giant and toy breeds) is needed. PMID:25313818

  17. 49 CFR 236.339 - Mechanical locking, maintenance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Mechanical locking, maintenance requirements. 236... Interlocking Rules and Instructions § 236.339 Mechanical locking, maintenance requirements. Locking and... prevented: (a) Mechanical machine—(1) Latch-operated locking. Raising lever latch block so that bottom...

  18. 78 FR 9798 - Airworthiness Directives; Dassault Aviation Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... Dassault Aviation Myst[egrave]re-Falcon 50 Aircraft Maintenance Manual (AMM) chapter 5-40 and approved by... manufacturer revision to the airplane maintenance manual (AMM) that introduces new or more restrictive maintenance requirements and airworthiness limitations. This AD requires revising the maintenance program to...

  19. 47 CFR 87.69 - Maintenance tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Maintenance tests. 87.69 Section 87.69... Operating Requirements and Procedures Operating Requirements § 87.69 Maintenance tests. The licensee may make routine maintenance tests on equipment other than emergency locator transmitters if there is no...

  20. “A System for Automatically Maintaining Pressure in a Commercial Truck Tire”

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Maloney, John

    2017-07-07

    Under-inflated tires significantly reduce a vehicle’s fuel efficiency by increasing rolling resistance (drag force). The Air Maintenance Technology (“AMT”) system developed through this project replenishes lost air and maintains optimal tire cavity pressure whenever the tire is rolling in service, thus improving overall fuel economy by reducing the tire’s rolling resistance. The system consists of an inlet air filter, an air pump driven by tire deformation during rotation, and a pressure regulating device. Pressurized air in the tire cavity naturally escapes by diffusion through the tire and wheel, leaks in tire seating, and through the filler valve and its seating.more » As a result, tires require constant maintenance to replenish lost air. Since manual tire inflation maintenance is both labor intensive and time consuming, it is frequently overlooked or ignored. By automating the maintenance of optimal tire pressure, the tire’s contribution to the vehicle’s overall fuel economy can be maximized. The work was divided into three phases. The objectives of Phase 1, Planning and Initial Design, resulted in an effective project plan and to create a baseline design. The objectives for Phase 2, Design and Process Optimization, were: to identify finalized design for the pump, regulator and filter components; identify a process to build prototype tires; assemble prototype tires; test prototype tires and document results. The objectives of Phase 3, Design Release and Industrialization, were to finalize system tire assembly, perform release testing and industrialize the assembly process.« less

  1. Reciprocal relationships between behaviour and parasites suggest that negative feedback may drive flexibility in male reproductive behaviour.

    PubMed

    Ezenwa, Vanessa O; Snider, Matthew H

    2016-05-25

    Parasites are ubiquitous components of the environment that contribute to behavioural and life-history variation among hosts. Although it is well known that host behaviour can affect parasite infection risk and that parasites can alter host behaviour, the potential for dynamic feedback between these processes is poorly characterized. Using Grant's gazelle (Nanger granti) as a model, we tested for reciprocal effects of behaviour on parasites and parasites on behaviour to understand whether behaviour-parasite feedback could play a role in maintaining variation in male reproductive behaviour. Adult male gazelles either defend territories to attract mates or reside in bachelor groups. Territoriality is highly variable both within- and between-individuals, suggesting that territory maintenance is costly. Using a combination of longitudinal and experimental studies, we found that individual males transition frequently between territorial and bachelor reproductive status, and that elevated parasite burdens are a cost of territoriality. Moreover, among territorial males, parasites suppress aspects of behaviour related to territory maintenance and defence. These results suggest that territorial behaviour promotes the accumulation of parasites in males, and these parasites dampen the very behaviours required for territory maintenance. Our findings suggest that reciprocal feedback between host behaviour and parasitism could be a mechanism maintaining variation in male reproductive behaviour in the system. © 2016 The Author(s).

  2. The relationship between substance use and posttraumatic stress disorder in a methadone maintenance treatment program.

    PubMed

    Villagonzalo, Kristi-Ann; Dodd, Seetal; Ng, Felicity; Mihaly, Stephen; Langbein, Amy; Berk, Michael

    2011-01-01

    Posttraumatic stress disorder (PTSD) is frequently linked with substance abuse. The self-medication hypothesis suggests that some people may use illicit substances in an attempt to self-treat psychiatric symptoms. This study explores the relationship between substance abuse and PTSD symptom clusters in a methadone maintenance population. Clients of a methadone maintenance program at a public Drug and Alcohol Service were invited to complete the PTSD Checklist-Civilian Version, a screening tool for PTSD. Information about their history of substance use was also collected. Eighty clients (43 female, 37 male), aged 35 ± 8.0 years (mean ± SD), participated in the study, of which 52.7% screened positive for PTSD. Severity of marijuana use was significantly associated with a number of reexperiencing and hyperarousal symptoms and with overall severity of PTSD symptoms. Opiate, amphetamine, and benzodiazepine use did not appear to be related to PTSD symptoms. In this sample, marijuana may be used to self-treat certain PTSD symptoms, supporting the self-medication hypothesis. Further research is required to confirm the association between a diagnosis of PTSD and substance use. Given the high prevalence of PTSD in the substance-using population, routine PTSD screening in the substance abuse treatment setting may be justified. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. 48 CFR 301.606-73 - Requirements for continuous learning maintenance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Requirements for continuous learning maintenance. 301.606-73 Section 301.606-73 Federal Acquisition Regulations System HEALTH..., and Responsibilities 301.606-73 Requirements for continuous learning maintenance. Designated Project...

  4. 48 CFR 301.606-73 - Requirements for continuous learning maintenance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Requirements for continuous learning maintenance. 301.606-73 Section 301.606-73 Federal Acquisition Regulations System HEALTH..., and Responsibilities 301.606-73 Requirements for continuous learning maintenance. Designated Project...

  5. 42 CFR 413.198 - Recordkeeping and cost reporting requirements for outpatient maintenance dialysis.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... outpatient maintenance dialysis. 413.198 Section 413.198 Public Health CENTERS FOR MEDICARE & MEDICAID... § 413.198 Recordkeeping and cost reporting requirements for outpatient maintenance dialysis. (a) Purpose... will enable CMS to determine the costs incurred in furnishing outpatient maintenance dialysis as...

  6. Responding to home maintenance challenge scenarios: the role of selection, optimization, and compensation in aging-in-place.

    PubMed

    Kelly, Andrew John; Fausset, Cara Bailey; Rogers, Wendy; Fisk, Arthur D

    2014-12-01

    This study examined potential issues faced by older adults in managing their homes and their proposed solutions for overcoming hypothetical difficulties. Forty-four diverse, independently living older adults (66-85) participated in structured group interviews in which they discussed potential solutions to manage difficulties presented in four scenarios: perceptual, mobility, physical, and cognitive difficulties. The proposed solutions were classified using the Selection, Optimization, and Compensation (SOC) model. Participants indicated they would continue performing most tasks and reported a range of strategies to manage home maintenance challenges. Most participants reported that they would manage home maintenance challenges using compensation; the most frequently mentioned compensation strategy was using tools and technologies. There were also differences across the scenarios: Optimization was discussed most frequently with perceptual and cognitive difficulty scenarios. These results provide insights into supporting older adults' potential needs for aging-in-place and provide evidence of the value of the SOC model in applied research. © The Author(s) 2012.

  7. Maintenance of weight loss: a needs assessment.

    PubMed

    DePue, J D; Clark, M M; Ruggiero, L; Medeiros, M L; Pera, V

    1995-05-01

    This study identified facilitators and obstacles to maintenance of weight loss following a very-low-calorie-diet and behavior modification program. A survey was mailed to a random sample of 178 program completers and received a 61% response rate; the most frequent follow-up period was more than 2 years. Twenty-nine percent reported weighing the same (within 10 lbs) or less than the end of their participation in the treatment program (maintainers), while 71% reported their present weight was a mean of 65% higher than their initial weight loss (regainers). Maintainers were significantly more likely to report engaging in regular aerobic exercise, attending a maintenance support group, and confidence in their ability to manage their weight in the future, while regainers were more likely to report stress and motivation as frequent weight management obstacles. Respondents consistently identified the need for low/no cost ongoing support. Maintainers and relapsers reported similar challenges in managing their weight, yet with different results, suggesting the need to identify subgroups for which different post-treatment support options could be applied.

  8. 14 CFR 171.103 - Requests for IFR procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... facility. (3) A proposed maintenance organization and a maintenance manual that meets the requirements of... facility has an acceptable level of operational reliability as prescribed in § 171.111(k), and an... the results and of any required changes in the facility or the maintenance manual or maintenance...

  9. 14 CFR 145.209 - Repair station manual contents.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...; (g) Procedures for maintenance, preventive maintenance, or alterations performed under § 145.205; (h)Procedures for— (1) Maintaining and revising the contract maintenance information required by § 145.217(a)(2...) Maintaining and revising the contract maintenance information required by § 145.217(a)(2)(ii) and notifying...

  10. Decreasing inventory of a cement factory roller mill parts using reliability centered maintenance method

    NASA Astrophysics Data System (ADS)

    Witantyo; Rindiyah, Anita

    2018-03-01

    According to data from maintenance planning and control, it was obtained that highest inventory value is non-routine components. Maintenance components are components which procured based on maintenance activities. The problem happens because there is no synchronization between maintenance activities and the components required. Reliability Centered Maintenance method is used to overcome the problem by reevaluating maintenance activities required components. The case chosen is roller mill system because it has the highest unscheduled downtime record. Components required for each maintenance activities will be determined by its failure distribution, so the number of components needed could be predicted. Moreover, those components will be reclassified from routine component to be non-routine component, so the procurement could be carried out regularly. Based on the conducted analysis, failure happens in almost every maintenance task are classified to become scheduled on condition task, scheduled discard task, schedule restoration task and no schedule maintenance. From 87 used components for maintenance activities are evaluated and there 19 components that experience reclassification from non-routine components to routine components. Then the reliability and need of those components were calculated for one-year operation period. Based on this invention, it is suggested to change all of the components in overhaul activity to increase the reliability of roller mill system. Besides, the inventory system should follow maintenance schedule and the number of required components in maintenance activity so the value of procurement will be decreased and the reliability system will increase.

  11. 42 CFR 124.510 - Record maintenance requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Record maintenance requirements. 124.510 Section 124.510 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH RESOURCES... Persons Unable To Pay § 124.510 Record maintenance requirements. (a) Facilities not certified under § 124...

  12. 42 CFR 124.510 - Record maintenance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Record maintenance requirements. 124.510 Section 124.510 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH RESOURCES... Persons Unable To Pay § 124.510 Record maintenance requirements. (a) Facilities not certified under § 124...

  13. 46 CFR 183.200 - General design, installation, and maintenance requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false General design, installation, and maintenance requirements. 183.200 Section 183.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION General Requirements § 183.200 General design, installation, and maintenance...

  14. 46 CFR 183.200 - General design, installation, and maintenance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false General design, installation, and maintenance requirements. 183.200 Section 183.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION General Requirements § 183.200 General design, installation, and maintenance...

  15. 46 CFR 183.200 - General design, installation, and maintenance requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false General design, installation, and maintenance requirements. 183.200 Section 183.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION General Requirements § 183.200 General design, installation, and maintenance...

  16. 46 CFR 183.200 - General design, installation, and maintenance requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false General design, installation, and maintenance requirements. 183.200 Section 183.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS (UNDER 100 GROSS TONS) ELECTRICAL INSTALLATION General Requirements § 183.200 General design, installation, and maintenance...

  17. 40 CFR 63.105 - Maintenance wastewater requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Maintenance wastewater requirements. 63... § 63.105 Maintenance wastewater requirements. (a) Each owner or operator of a source subject to this... wastewaters containing those organic HAP's listed in table 9 of subpart G of this part. (b) The owner or...

  18. The Maintenance of Heating, Ventilating and Air-Conditioning Systems and Indoor Air Quality in Schools: A Guide for School Facility Managers. Technical Bulletin.

    ERIC Educational Resources Information Center

    Wheeler, Arthur E.

    To help maintain good indoor air quality (IAQ) in schools, guidance for the development and implementation of an effective program for maintenance and operation of heating, ventilating, and air-conditioning (HVAC) systems are discussed. Frequently, a building's occupants will complain about IAQ when the temperature or humidity are at uncomfortable…

  19. 49 CFR 214.509 - Required visual illumination and reflective devices for new on-track roadway maintenance machines.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... devices for new on-track roadway maintenance machines. 214.509 Section 214.509 Transportation Other... TRANSPORTATION RAILROAD WORKPLACE SAFETY On-Track Roadway Maintenance Machines and Hi-Rail Vehicles § 214.509 Required visual illumination and reflective devices for new on-track roadway maintenance machines. Each new...

  20. PFP Emergency Lighting Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    BUSCH, M.S.

    2000-02-02

    NFPA 101, section 5-9 mandates that, where required by building classification, all designated emergency egress routes be provided with adequate emergency lighting in the event of a normal lighting outage. Emergency lighting is to be arranged so that egress routes are illuminated to an average of 1.0 footcandle with a minimum at any point of 0.1 footcandle, as measured at floor level. These levels are permitted to drop to 60% of their original value over the required 90 minute emergency lighting duration after a power outage. The Plutonium Finishing Plant (PFP) has two designations for battery powered egress lights ''Emergencymore » Lights'' are those battery powered lights required by NFPA 101 to provide lighting along officially designated egress routes in those buildings meeting the correct occupancy requirements. Emergency Lights are maintained on a monthly basis by procedure ZSR-12N-001. ''Backup Lights'' are battery powered lights not required by NFPA, but installed in areas where additional light may be needed. The Backup Light locations were identified by PFP Safety and Engineering based on several factors. (1) General occupancy and type of work in the area. Areas occupied briefly during a shiftly surveillance do not require backup lighting while a room occupied fairly frequently or for significant lengths of time will need one or two Backup lights to provide general illumination of the egress points. (2) Complexity of the egress routes. Office spaces with a standard hallway/room configuration will not require Backup Lights while a large room with several subdivisions or irregularly placed rooms, doors, and equipment will require Backup Lights to make egress safer. (3) Reasonable balance between the safety benefits of additional lighting and the man-hours/exposure required for periodic light maintenance. In some plant areas such as building 236-Z, the additional maintenance time and risk of contamination do not warrant having Backup Lights installed in all rooms. Sufficient light for egress is provided by existing lights located in the hallways.« less

  1. AN INVESTIGATION OF THE TRAINING AND SKILL REQUIREMENTS OF INDUSTRIAL MACHINERY MAINTENANCE WORKERS. VOLUME II. FINAL REPORT.

    ERIC Educational Resources Information Center

    LYNN, FRANK

    THE APPENDIXES FOR "AN INVESTIGATION OF THE TRAINING AND SKILL REQUIREMENTS OF INDUSTRIAL MACHINERY MAINTENANCE WORKERS, FINAL REPORT, VOLUME I" (VT 004 006) INCLUDE (1) TWO LETTERS FROM PLANT ENGINEERS STRESSING THE IMPORTANCE OF TRAINING MACHINERY MAINTENANCE WORKERS, (2) A DESCRIPTION OF THE MAINTENANCE TRAINING SURVEY, A SAMPLE QUESTIONNAIRE,…

  2. Clinical management and outcome of refractory asthma in the UK from the British Thoracic Society Difficult Asthma Registry.

    PubMed

    Sweeney, Joan; Brightling, Chris E; Menzies-Gow, Andrew; Niven, Robert; Patterson, Chris C; Heaney, Liam G

    2012-08-01

    Refractory asthma represents a significant unmet clinical need. Data from a national online registry audited clinical outcome in 349 adults with refractory asthma from four UK specialist centres in the British Thoracic Society Difficult Asthma Network. At follow-up, lung function improved, with a reduction in important healthcare outcomes, specifically hospital admission, unscheduled healthcare visits and rescue courses of oral steroids. The most frequent therapeutic intervention was maintenance oral corticosteroids and most steroid sparing agents (apart from omalizumab) demonstrated minimal steroid sparing benefit. A significant unmet clinical need remains in this group, specifically a requirement for therapies which reduce systemic steroid exposure.

  3. Facilities maintenance handbook

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This handbook is a guide for facilities maintenance managers. Its objective is to set minimum facilities maintenance standards. It also provides recommendations on how to meet the standards to ensure that NASA maintains its facilities in a manner that protects and preserves its investment in the facilities in a cost-effective manner while safely and efficiently performing its mission. This handbook implements NMI 8831.1, which states NASA facilities maintenance policy and assigns organizational responsibilities for the management of facilities maintenance activities on all properties under NASA jurisdiction. It is a reference for facilities maintenance managers, not a step-by-step procedural manual. Because of the differences in NASA Field Installation organizations, this handbook does not assume or recommend a typical facilities maintenance organization. Instead, it uses a systems approach to describe the functions that should be included in any facilities maintenance management system, regardless of its organizational structure. For documents referenced in the handbook, the most recent version of the documents is applicable. This handbook is divided into three parts: Part 1 specifies common definitions and facilities maintenance requirements and amplifies the policy requirements contained in NMI 8831. 1; Part 2 provides guidance on how to meet the requirements of Part 1, containing recommendations only; Part 3 contains general facilities maintenance information. One objective of this handbook is to fix commonality of facilities maintenance definitions among the Centers. This will permit the application of uniform measures of facilities conditions, of the relationship between current replacement value and maintenance resources required, and of the backlog of deferred facilities maintenance. The utilization of facilities maintenance system functions will allow the Centers to quantitatively define maintenance objectives in common terms, prepare work plans, and develop management information in order to statistically identify and analyze variances from those plans. It will also add credibility to the NASA facilities maintenance budgeting process. The key to a successful maintenance program is the understanding and support of the senior Center managers.

  4. Using decision-tree classifier systems to extract knowledge from databases

    NASA Technical Reports Server (NTRS)

    St.clair, D. C.; Sabharwal, C. L.; Hacke, Keith; Bond, W. E.

    1990-01-01

    One difficulty in applying artificial intelligence techniques to the solution of real world problems is that the development and maintenance of many AI systems, such as those used in diagnostics, require large amounts of human resources. At the same time, databases frequently exist which contain information about the process(es) of interest. Recently, efforts to reduce development and maintenance costs of AI systems have focused on using machine learning techniques to extract knowledge from existing databases. Research is described in the area of knowledge extraction using a class of machine learning techniques called decision-tree classifier systems. Results of this research suggest ways of performing knowledge extraction which may be applied in numerous situations. In addition, a measurement called the concept strength metric (CSM) is described which can be used to determine how well the resulting decision tree can differentiate between the concepts it has learned. The CSM can be used to determine whether or not additional knowledge needs to be extracted from the database. An experiment involving real world data is presented to illustrate the concepts described.

  5. Embryonic origin of adult stem cells required for tissue homeostasis and regeneration

    PubMed Central

    Davies, Erin L; Lei, Kai; Seidel, Christopher W; Kroesen, Amanda E; McKinney, Sean A; Guo, Longhua; Robb, Sofia MC; Ross, Eric J; Gotting, Kirsten; Alvarado, Alejandro Sánchez

    2017-01-01

    Planarian neoblasts are pluripotent, adult somatic stem cells and lineage-primed progenitors that are required for the production and maintenance of all differentiated cell types, including the germline. Neoblasts, originally defined as undifferentiated cells residing in the adult parenchyma, are frequently compared to embryonic stem cells yet their developmental origin remains obscure. We investigated the provenance of neoblasts during Schmidtea mediterranea embryogenesis, and report that neoblasts arise from an anarchic, cycling piwi-1+ population wholly responsible for production of all temporary and definitive organs during embryogenesis. Early embryonic piwi-1+ cells are molecularly and functionally distinct from neoblasts: they express unique cohorts of early embryo enriched transcripts and behave differently than neoblasts in cell transplantation assays. Neoblast lineages arise as organogenesis begins and are required for construction of all major organ systems during embryogenesis. These subpopulations are continuously generated during adulthood, where they act as agents of tissue homeostasis and regeneration. DOI: http://dx.doi.org/10.7554/eLife.21052.001 PMID:28072387

  6. 14 CFR 147.3 - Certificate required.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OTHER CERTIFICATED AGENCIES AVIATION MAINTENANCE TECHNICIAN SCHOOLS General § 147.3 Certificate required. No person may operate as a certificated aviation maintenance technician school without, or in violation of, an aviation maintenance technician school certificate issued under this part. [Doc. No. 15196...

  7. Passive RFID Localisation Framework in Smart Homes Healthcare Settings.

    PubMed

    Alsinglawi, Belal; Liu, Tony; Nguyen, Quang Vinh; Gunawardana, Upul; Maeder, Anthony; Simoff, Simeon

    2016-01-01

    In recent years, Smart Homes have become a solution to benefit impaired individuals and elderly in their daily life settings. In healthcare applications, pervasive technologies have enabled the practicality of personal monitoring using Indoor positioning technologies. Radio-Frequency Identification (RFID) is a promising technology, which is useful for non-invasive tracking of activities of daily living. Many implementations have focused on using battery-enabled tags like in RFID active tags, which require frequent maintenance and they are costly. Other systems can use wearable sensors requiring individuals to wear tags which may be inappropriate for elders. Successful implementations of a tracking system are dependent on multiple considerations beyond the physical performance of the solution, such as affordability and human acceptance. This paper presents a localisation framework using passive RFID sensors. It aims to provide a low cost solution for subject location in Smart Homes healthcare.

  8. 14 CFR 171.325 - Maintenance and operations requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Maintenance and operations requirements. 171.325 Section 171.325 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... service. (7) Detailed and specific maintenance procedures and servicing guides stating the frequency of...

  9. 14 CFR 171.325 - Maintenance and operations requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Maintenance and operations requirements. 171.325 Section 171.325 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... service. (7) Detailed and specific maintenance procedures and servicing guides stating the frequency of...

  10. 14 CFR 171.325 - Maintenance and operations requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Maintenance and operations requirements. 171.325 Section 171.325 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... service. (7) Detailed and specific maintenance procedures and servicing guides stating the frequency of...

  11. 14 CFR 171.325 - Maintenance and operations requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Maintenance and operations requirements. 171.325 Section 171.325 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... service. (7) Detailed and specific maintenance procedures and servicing guides stating the frequency of...

  12. 14 CFR 171.325 - Maintenance and operations requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Maintenance and operations requirements. 171.325 Section 171.325 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... service. (7) Detailed and specific maintenance procedures and servicing guides stating the frequency of...

  13. 14 CFR 171.161 - Maintenance and operations requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... meet at a minimum the Federal Communications Commission's licensing requirements and show that he has the special knowledge and skills needed to maintain the facility, including proficiency in maintenance... facility. (2) Maintenance and operations by authorized persons only. (3) Federal Communications Commission...

  14. 14 CFR 171.161 - Maintenance and operations requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... meet at a minimum the Federal Communications Commission's licensing requirements and show that he has the special knowledge and skills needed to maintain the facility, including proficiency in maintenance... facility. (2) Maintenance and operations by authorized persons only. (3) Federal Communications Commission...

  15. 14 CFR 171.161 - Maintenance and operations requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... meet at a minimum the Federal Communications Commission's licensing requirements and show that he has the special knowledge and skills needed to maintain the facility, including proficiency in maintenance... facility. (2) Maintenance and operations by authorized persons only. (3) Federal Communications Commission...

  16. 14 CFR 171.161 - Maintenance and operations requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... meet at a minimum the Federal Communications Commission's licensing requirements and show that he has the special knowledge and skills needed to maintain the facility, including proficiency in maintenance... facility. (2) Maintenance and operations by authorized persons only. (3) Federal Communications Commission...

  17. The development of a computerized maintenance management system at the New York State Department of Environmental Conservation

    Treesearch

    Francis V. Riedy; Daniel Skelton

    1998-01-01

    Every asset, old or new, requires maintenance. Buildings, bridges, roads, dams, utilities and grounds; each requires some degree of maintenance to ensure long life cycles and safe operation. Maintenance is science, art and philosophy. It is science since its execution ultimately relies on most of all the sciences; it is art because seemingly identical problems...

  18. Estimating cost per lane mile for routine highway operations and maintenance

    DOT National Transportation Integrated Search

    2011-01-01

    The disparity between maintenance budgets and maintenance requirements causes agencies to make difficult choices : about maintenance priorities. There is a growing need to effectively link maintenance costs and condition to provide clear : evidence o...

  19. How to Cut Landscape Maintenance Costs.

    ERIC Educational Resources Information Center

    Brickman, Dick

    1982-01-01

    A landscape architect explains how maintenance requirements and costs are affected by landscape design, the physical demands of the site, and the relative use of grass, ground cover, shrubs, and trees. The relationship of these factors to initial and ongoing maintenance costs, including staff requirements, is discussed. (MLF)

  20. 77 FR 21429 - Airworthiness Directives; The Boeing Company Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ... the maintenance planning document. This AD requires revising the maintenance program to update... Engineer, Airframe Branch, ANM-120S, FAA, Seattle Aircraft Certification Office, 1601 Lind Avenue SW... Register on January 19, 2011 (76 FR 3054). That NPRM proposed to require revising the maintenance program...

  1. Crew interface specifications development functions, phase 3A

    NASA Technical Reports Server (NTRS)

    Carl, J. G.

    1973-01-01

    The findings and data products developed during the crew interface specification study for inflight maintenance and stowage functions are presented. Guidelines are provided for improving the present progress of defining, controlling, and managing the flight crew requirements. The following data products were developed: (1) description of inflight maintenance management process, (2) specifications for inflight maintenance management requirements, and (3) suggested inflight maintenance data processing reports for logistics management.

  2. 48 CFR 301.604-72 - Requirements for certification maintenance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Responsibilities 301.604-72 Requirements for certification maintenance. Maintaining HHS FAC-COTR certification requires at least 40 relevant CLPs every 2 years. See Appendix A of OFPP's FAC-COTR memorandum, dated...

  3. 48 CFR 301.604-72 - Requirements for certification maintenance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Responsibilities 301.604-72 Requirements for certification maintenance. Maintaining HHS FAC-COTR certification requires at least 40 relevant CLPs every 2 years. See Appendix A of OFPP's FAC-COTR memorandum, dated...

  4. 48 CFR 301.604-72 - Requirements for certification maintenance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Responsibilities 301.604-72 Requirements for certification maintenance. Maintaining HHS FAC-COTR certification requires at least 40 relevant CLPs every 2 years. See Appendix A of OFPP's FAC-COTR memorandum, dated...

  5. 48 CFR 301.604-72 - Requirements for certification maintenance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Responsibilities 301.604-72 Requirements for certification maintenance. Maintaining HHS FAC-COTR certification requires at least 40 relevant CLPs every 2 years. See Appendix A of OFPP's FAC-COTR memorandum, dated...

  6. 48 CFR 301.604-72 - Requirements for certification maintenance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Responsibilities 301.604-72 Requirements for certification maintenance. Maintaining HHS FAC-COTR certification requires at least 40 relevant CLPs every 2 years. See Appendix A of OFPP's FAC-COTR memorandum, dated...

  7. Crew interface specifications preparation for in-flight maintenance and stowage functions

    NASA Technical Reports Server (NTRS)

    Parker, F. W.; Carlton, B. E.

    1972-01-01

    The findings and data products developed during the Phase 2 crew interface specification study are presented. Five new NASA general specifications were prepared: operations location coding system for crew interfaces; loose equipment and stowage management requirements; loose equipment and stowage data base information requirements; spacecraft loose equipment stowage drawing requirements; and inflight stowage management data requirements. Additional data was developed defining inflight maintenance processes and related data concepts for inflight troubleshooting, remove/repair/replace and scheduled maintenance activities. The process of maintenance task and equipment definition during spacecraft design and development was also defined and related data concepts were identified for futher development into formal NASA specifications during future follow-on study phases of the contract.

  8. [Development of Hospital Equipment Maintenance Information System].

    PubMed

    Zhou, Zhixin

    2015-11-01

    Hospital equipment maintenance information system plays an important role in improving medical treatment quality and efficiency. By requirement analysis of hospital equipment maintenance, the system function diagram is drawed. According to analysis of input and output data, tables and reports in connection with equipment maintenance process, relationships between entity and attribute is found out, and E-R diagram is drawed and relational database table is established. Software development should meet actual process requirement of maintenance and have a friendly user interface and flexible operation. The software can analyze failure cause by statistical analysis.

  9. Operation and maintenance manual for a preprototype Sabatier carbon dioxide reduction subsystem

    NASA Technical Reports Server (NTRS)

    Kleiner, G. N.

    1981-01-01

    The manual delineates the procedures, precautions and necessary sequences of steps required to prepare the package for test, provide troubleshooting information and perform required maintenance by the operating crew. The manual is divided into five sections: Installation, Checkout, Operation, Failure Detection/Isolation and Maintenance.

  10. 14 CFR 171.305 - Requests for IFR procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... maintenance manual that meets the requirements of § 171.325. (4) A statement of intent to meet the... reliability and an acceptable standard of performance. Previous equivalent operational experience with a... results, and of any required changes in the MLS facility or in the maintenance manual or maintenance...

  11. 14 CFR 1212.601 - Maintenance and publication requirements for systems of records.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Maintenance and publication requirements for systems of records. 1212.601 Section 1212.601 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS Instructions for NASA Employees § 1212.601 Maintenance and...

  12. 14 CFR 1212.601 - Maintenance and publication requirements for systems of records.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Maintenance and publication requirements for systems of records. 1212.601 Section 1212.601 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS Instructions for NASA Employees § 1212.601 Maintenance and...

  13. 75 FR 80567 - Agency Information Collection Activities: Requests for Comments; Clearance of Renewed Approval of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-22

    ... Aviation Maintenance Technician Schools meet the minimum requirements for procedures and curriculum set forth by the FAA in FAR Part 147. Applicants submit FAA Form 8310-6, Aviation Maintenance Technician... FAR Part 147 requirements have been met, an aviation maintenance technician school certificate with...

  14. Test, Control and Monitor System maintenance plan

    NASA Technical Reports Server (NTRS)

    Buehler, David P.; Lougheed, M. J.

    1993-01-01

    The maintenance requirements for Test, Control, and Monitor System (TCMS) and the method for satisfying these requirements prior to First Need Date (FND) of the last TCMS set are described. The method for satisfying maintenance requirements following FND of the last TCMS set will be addressed by a revision to this plan. This maintenance plan serves as the basic planning document for maintenance of this equipment by the NASA Payloads Directorate (CM) and the Payload Ground Operations Contractor (PGOC) at KSC. The terms TCMS Operations and Maintenance (O&M), Payloads Logistics, TCMS Sustaining Engineering, Payload Communications, and Integrated Network Services refer to the appropriate NASA and PGOC organization. For the duration of their contract, the Core Electronic Contractor (CEC) will provide a Set Support Team (SST). One of the primary purposes of this team is to help NASA and PGOC operate and maintain TCMS. It is assumed that SST is an integral part of TCMS O&M. The purpose of this plan is to describe the maintenance concept for TCMS hardware and system software in order to facilitate activation, transition planning, and continuing operation. When software maintenance is mentioned in this plan, it refers to maintenance of TCMS system software.

  15. Case Series Report of 66 Refractory Maintenance Patients Evaluating the Effectiveness of Topical Oxidizing Agents.

    PubMed

    Cochrane, R Bruce; Sindelar, Betty

    2015-01-01

    To evaluate the clinical effects of a prescription tray application of hydrogen peroxide gel as an adjunct to frequent maintenance appointments for refractory periodontal patients. Case series data were analyzed from 66 failing periodontal maintenance patients who had exhausted treatment options before using prescription trays with a 1.7% hydrogen peroxide gel once or twice daily for two-and-a-half to five years. Data included pocket probing depths (PPD), bleeding on probing (BOP), smoking status, and compliance with tray usage. Data were collected prior to tray usage and after tray delivery at six months, one year, and annual intervals. A clinical and statistical reduction in BOP was maintained over the length of the study (p ≤ 0.01). No differences were seen in patients who used trays two times or one time a day or in patients who smoked or did not smoke. The 1.7% peroxide delivered via a prescription tray was most effective in shallow pockets. Aggregate PPD distribution did not change significantly. Of clinical relevance, only one tooth out of 1,745 teeth studied was lost due to periodontal disease during the study period. Prescription tray application of peroxide gel, as an adjunct to frequent periodontal maintenance appointments for refractory patients, demonstrated significant reductions in BOP'for smokers and non-smokers who used tray delivery once or twice a day.

  16. Stranded: causes and effects of discharge delays involving non-acute in-patients requiring maintenance care in a tertiary hospital general medicine service.

    PubMed

    Salonga-Reyes, Armi; Scott, Ian A

    2017-03-01

    Objectives The aims of the present study were to identify causes of prolonged discharge delays among non-acute in-patients admitted to a tertiary general medicine service, quantify occupied bed days (OBDs) and propose strategies for eliminating avoidable delays. Methods A retrospective study was performed of patients admitted between 1 January 2012 and 31 May 2015 and discharged as non-acute cases requiring maintenance care and who incurred a total non-acute length of stay (LOS) >7 days and total hospital LOS >14 days. Long-stay patients with non-acute LOS ≥28 days were subject to chart review in ascertaining serial causes of discharge delay and their attributable OBDs. Literature reviews and staff feedback identified potential strategies for minimising delays. Results Of the 406 patients included in the present study, 131 incurred long-stays; for these 131 patients, delays were identified that accounted for 5420 of 6033 (90%) non-acute OBDs. Lack of available residential care beds was most frequent, accounting for 44% of OBDs. Waits for outcomes of guardianship applications accounted for 13%, whereas guardian appointments, Public Trustee applications and funding decisions for equipment or care packages each consumed between 4% and 5% of OBDs. Family and/or carer refusal of care accounted for 7%. Waits for aged care assessment team (ACAT) assessments, social worker reports, geriatrician or psychiatrist reviews and confirmation of enduring power of attorney each accounted for between 1% and 3% of OBDs. Of 30 proposed remedial strategies, those rated as high priority were: greater access to interim care or respite care beds or supported accommodation, especially for patients with special needs; dedicated agency officers for hospital guardianship applications and greater interagency collaboration and harmonisation of assessment and decision processes; and formal requests from hospital administrators to patients and family to accept care options and attend mediation meetings. Conclusions Delayed discharge of non-acute maintenance care patients results principally from impaired access to residential care, administrative delays involving external agencies and patient or family refusal of care. Proposed remedial actions require concerted interjurisdictional advocacy. What is known about this topic? Delays in discharge of non-acute patients requiring maintenance care can occur for many reasons and incur inordinately long hospital stays. What does this paper add? The present detailed chart review of 131 long-stay non-acute patients identified causes of serial discharge delays and quantified their prevalence and attributable bed days. Waits for residential care accounted for less than half the bed days, administrative delays involving decisions by agencies external to the hospital accounted for one-quarter and patient or family refusal of care options accounted for one-tenth. Strategies are proposed that may minimise these delays. What are the implications for practitioners? Delayed discharge of non-acute patients requiring maintenance care threatens to consume an ever-increasing proportion of acute hospital bed days. Remedial action is required from stakeholders both within and outside hospitals to reverse this trend.

  17. 40 CFR 267.33 - What are the testing and maintenance requirements for the equipment?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OPERATING UNDER A STANDARDIZED PERMIT Preparedness and Prevention § 267.33 What are the testing and maintenance requirements for the equipment? You must test and maintain all required facility communications or...

  18. 40 CFR 267.33 - What are the testing and maintenance requirements for the equipment?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OPERATING UNDER A STANDARDIZED PERMIT Preparedness and Prevention § 267.33 What are the testing and maintenance requirements for the equipment? You must test and maintain all required facility communications or...

  19. 40 CFR 267.33 - What are the testing and maintenance requirements for the equipment?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... OPERATING UNDER A STANDARDIZED PERMIT Preparedness and Prevention § 267.33 What are the testing and maintenance requirements for the equipment? You must test and maintain all required facility communications or...

  20. 40 CFR 267.33 - What are the testing and maintenance requirements for the equipment?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... OPERATING UNDER A STANDARDIZED PERMIT Preparedness and Prevention § 267.33 What are the testing and maintenance requirements for the equipment? You must test and maintain all required facility communications or...

  1. 40 CFR 267.33 - What are the testing and maintenance requirements for the equipment?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OPERATING UNDER A STANDARDIZED PERMIT Preparedness and Prevention § 267.33 What are the testing and maintenance requirements for the equipment? You must test and maintain all required facility communications or...

  2. Integrating O/S models during conceptual design, part 3

    NASA Technical Reports Server (NTRS)

    Ebeling, Charles E.

    1994-01-01

    Space vehicles, such as the Space Shuttle, require intensive ground support prior to, during, and after each mission. Maintenance is a significant part of that ground support. All space vehicles require scheduled maintenance to ensure operability and performance. In addition, components of any vehicle are not one-hundred percent reliable so they exhibit random failures. Once detected, a failure initiates unscheduled maintenance on the vehicle. Maintenance decreases the number of missions which can be completed by keeping vehicles out of service so that the time between the completion of one mission and the start of the next is increased. Maintenance also requires resources such as people, facilities, tooling, and spare parts. Assessing the mission capability and resource requirements of any new space vehicle, in addition to performance specification, is necessary to predict the life cycle cost and success of the vehicle. Maintenance and logistics support has been modeled by computer simulation to estimate mission capability and resource requirements for evaluation of proposed space vehicles. The simulation was written with Simulation Language for Alternative Modeling II (SLAM II) for execution on a personal computer. For either one or a fleet of space vehicles, the model simulates the preflight maintenance checks, the mission and return to earth, and the post flight maintenance in preparation to be sent back into space. THe model enables prediction of the number of missions possible and vehicle turn-time (the time between completion of one mission and the start of the next) given estimated values for component reliability and maintainability. The model also facilitates study of the manpower and vehicle requirements for the proposed vehicle to meet its desired mission rate. This is the 3rd part of a 3 part technical report.

  3. 77 FR 38569 - Information Collection; Application for Permit for Use of Roads, Trails, or Areas Restricted by...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... investments in NFS roads; and require commercial users to perform road maintenance commensurate with their use... commercial users to perform maintenance commensurate with their road use. Section 261.10 contains a national... appropriate investment sharing arrangements, require commercial users of NFS roads to perform maintenance...

  4. 30 CFR 250.446 - What are the BOP maintenance and inspection requirements?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ....11, Maintenance; and Sections 17.12 and 18.12, Quality Management, described in API RP 53... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What are the BOP maintenance and inspection requirements? 250.446 Section 250.446 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR...

  5. The Public School Infrastructure Problem: Deteriorating Buildings and Deferred Maintenance

    ERIC Educational Resources Information Center

    Hunter, Richard C.

    2009-01-01

    The deterioration of public school buildings is more prevalent in large cities that, because of funding shortfalls, have deferred maintenance and require huge sums to bring their buildings up to acceptable standards. Cities such as New York will require approximately $680 million to address the problem of deferred maintenance for needed painting,…

  6. 46 CFR 15.1107 - Maintenance of merchant mariners' records by owner or operator.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Maintenance of merchant mariners' records by owner or operator. 15.1107 Section 15.1107 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN MANNING REQUIREMENTS Vessels Subject to Requirements of STCW § 15.1107 Maintenance of...

  7. 46 CFR 15.1107 - Maintenance of merchant mariners' records by owner or operator.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Maintenance of merchant mariners' records by owner or operator. 15.1107 Section 15.1107 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN MANNING REQUIREMENTS Vessels Subject to Requirements of STCW § 15.1107 Maintenance of...

  8. 46 CFR 15.1107 - Maintenance of merchant mariners' records by owner or operator.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Maintenance of merchant mariners' records by owner or operator. 15.1107 Section 15.1107 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN MANNING REQUIREMENTS Vessels Subject to Requirements of STCW § 15.1107 Maintenance of...

  9. 10 CFR 50.65 - Requirements for monitoring the effectiveness of maintenance at nuclear power plants.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... maintenance at nuclear power plants. 50.65 Section 50.65 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... Construction Permits § 50.65 Requirements for monitoring the effectiveness of maintenance at nuclear power..., including normal shutdown operations. (a)(1) Each holder of an operating license for a nuclear power plant...

  10. 10 CFR 50.65 - Requirements for monitoring the effectiveness of maintenance at nuclear power plants.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... maintenance at nuclear power plants. 50.65 Section 50.65 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... Construction Permits § 50.65 Requirements for monitoring the effectiveness of maintenance at nuclear power..., including normal shutdown operations. (a)(1) Each holder of an operating license for a nuclear power plant...

  11. 10 CFR 50.65 - Requirements for monitoring the effectiveness of maintenance at nuclear power plants.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... maintenance at nuclear power plants. 50.65 Section 50.65 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... Construction Permits § 50.65 Requirements for monitoring the effectiveness of maintenance at nuclear power..., including normal shutdown operations. (a)(1) Each holder of an operating license for a nuclear power plant...

  12. 10 CFR 50.65 - Requirements for monitoring the effectiveness of maintenance at nuclear power plants.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... maintenance at nuclear power plants. 50.65 Section 50.65 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... Construction Permits § 50.65 Requirements for monitoring the effectiveness of maintenance at nuclear power..., including normal shutdown operations. (a)(1) Each holder of an operating license for a nuclear power plant...

  13. 36 CFR 1236.28 - What additional requirements apply to the selection and maintenance of electronic records storage...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... apply to the selection and maintenance of electronic records storage media for permanent records? 1236... What additional requirements apply to the selection and maintenance of electronic records storage media for permanent records? (a) Agencies must maintain the storage and test areas for electronic records...

  14. 36 CFR 1236.28 - What additional requirements apply to the selection and maintenance of electronic records storage...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... apply to the selection and maintenance of electronic records storage media for permanent records? 1236... What additional requirements apply to the selection and maintenance of electronic records storage media for permanent records? (a) Agencies must maintain the storage and test areas for electronic records...

  15. Maintenance energy requirement of llamas.

    PubMed

    Carmean, B R; Johnson, K A; Johnson, D E; Johnson, L W

    1992-09-01

    Five castrated male llamas (mean body weight, 94 kg) were studied in an energy balance trial to determine maintenance energy requirement of llamas. Llamas were fed a 50% oat hay-50% pelleted concentrate diet (2.43 Mcal of metabolizable energy/kg of diet dry matter) at approximately 1.6% of body weight (BW). An 8-day total collection digestion trial was used to determine fecal and urine energy losses. Heat production and methane emissions were determined via indirect respiration calorimetry measurements on each llama fed at the same level of intake as during the digestion trial and subsequently on days 3 and 4 of a period of nonfeeding. Fecal, urine, and methane energy losses of the llamas fed near-maintenance intake were 32.5, 3.5, and 7.1% of gross energy intake, respectively. The postabsorptive metabolic rate, commonly called nonfed (fasting) heat production, was 59.3 kcal/BW0.75. Using a linear relation between postabsorptive and maintenance energy requirement and efficiency of energy use below maintenance of 0.702, metabolizable energy requirement at maintenance was determined to be 84.5 kcal/BW0.75.

  16. 14 CFR 121.374 - Continuous airworthiness maintenance program (CAMP) for two-engine ETOPS.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Continuous airworthiness maintenance...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Maintenance, Preventive Maintenance, and Alterations § 121.374 Continuous airworthiness maintenance program (CAMP) for two...

  17. 14 CFR 121.374 - Continuous airworthiness maintenance program (CAMP) for two-engine ETOPS.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Continuous airworthiness maintenance...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Maintenance, Preventive Maintenance, and Alterations § 121.374 Continuous airworthiness maintenance program (CAMP) for two...

  18. 14 CFR 121.374 - Continuous airworthiness maintenance program (CAMP) for two-engine ETOPS.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Continuous airworthiness maintenance...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Maintenance, Preventive Maintenance, and Alterations § 121.374 Continuous airworthiness maintenance program (CAMP) for two...

  19. 14 CFR 121.374 - Continuous airworthiness maintenance program (CAMP) for two-engine ETOPS.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Continuous airworthiness maintenance...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Maintenance, Preventive Maintenance, and Alterations § 121.374 Continuous airworthiness maintenance program (CAMP) for two...

  20. 14 CFR 121.374 - Continuous airworthiness maintenance program (CAMP) for two-engine ETOPS.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Continuous airworthiness maintenance...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Maintenance, Preventive Maintenance, and Alterations § 121.374 Continuous airworthiness maintenance program (CAMP) for two...

  1. 40 CFR 63.1572 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Requirements § 63.1572 What are my monitoring installation, operation, and maintenance requirements? (a) You... requirements in paragraphs (a)(1) through (4) of this section. (1) You must install, operate, and maintain each continuous emission monitoring system according to the requirements in Table 40 of this subpart. (2) If you...

  2. 47 CFR 80.1105 - Maintenance requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Maintenance requirements. 80.1105 Section 80.1105 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Equipment Requirements...

  3. 47 CFR 80.1105 - Maintenance requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Maintenance requirements. 80.1105 Section 80.1105 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Equipment Requirements...

  4. 47 CFR 80.1105 - Maintenance requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Maintenance requirements. 80.1105 Section 80.1105 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Equipment Requirements...

  5. 47 CFR 80.1105 - Maintenance requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Maintenance requirements. 80.1105 Section 80.1105 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Equipment Requirements...

  6. Predictors of physical activity levels of individuals following traumatic brain injury remain unclear: A systematic review.

    PubMed

    Hamilton, Megan; Khan, Michelle; Clark, Ross; Williams, Gavin; Bryant, Adam

    2016-01-01

    To identify factors which influence physical activity levels (PALs) of people with traumatic brain injury (TBI). Eight electronic databases. A systematic search was performed to identify articles that reported the measurement (quantity) of PALs of individuals with TBI. Two authors reviewed andextracted the data independently. Article quality was evaluated using the Law critical review tool. Six studies were identified that met the inclusion criteria. All studies found that PALs of participants with TBI were below those recommended for health benefits. Although a number of environmental and personal barriers restricted PA participation, motivation and exercise self-efficacy were the most frequently identified facilitators of PA in the TBI population. Despite apparent links, the relationship between mobility capacity and PALs was unclear from the results of this systematic review. The results of this systematic review demonstrated that little is known about PALs of individuals with TBI. PALs of participants with TBI were less than required for health maintenance. Self-efficacy to exercise and motivation were the most frequently identified facilitators of PA in the TBI population.

  7. How to Care for Your Septic System

    EPA Pesticide Factsheets

    Septic system maintenance is not complicated, and it does not need to be expensive. Upkeep comes down to four key elements: Inspect and Pump Frequently, Use Water Efficiently, Properly Dispose of Waste and Maintain Your Drainfield.

  8. 78 FR 61164 - Airworthiness Directives; The Boeing Company Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ... have been found in inner cylinder pivot bores due to friction-generated heat damage. More frequent lubrication reduces friction in the joint. Also, the Boeing 767-200/-300/-300F maintenance planning document...

  9. Using modeling and simulation tools for work zone analysis

    DOT National Transportation Integrated Search

    2009-05-01

    Work Zone Planning and Management have become more challenging because of increasing travel demand and an aging roadway network infrastructure facing more frequent maintenance and major rehabilitation projects, while still needing to transport people...

  10. 24 CFR 266.507 - Maintenance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.507 Maintenance requirements. The mortgagor must maintain the project in...

  11. 24 CFR 266.507 - Maintenance requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.507 Maintenance requirements. The mortgagor must maintain the project in...

  12. 24 CFR 266.507 - Maintenance requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.507 Maintenance requirements. The mortgagor must maintain the project in...

  13. 24 CFR 266.507 - Maintenance requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.507 Maintenance requirements. The mortgagor must maintain the project in...

  14. 24 CFR 266.507 - Maintenance requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project Management and Servicing § 266.507 Maintenance requirements. The mortgagor must maintain the project in...

  15. Comparison of F(ab')2 versus Fab antivenom for pit viper envenomation: A prospective, blinded, multicenter, randomized clinical trial

    PubMed Central

    Ruha, Anne-Michelle; Seifert, Steven A.; Morgan, David L.; Lewis, Brandon J.; Arnold, Thomas C.; Clark, Richard F.; Meggs, William J.; Toschlog, Eric A.; Borron, Stephen W.; Figge, Gary R.; Sollee, Dawn R.; Shirazi, Farshad M.; Wolk, Robert; de Chazal, Ives; Quan, Dan; García-Ubbelohde, Walter; Alagón, Alejandro; Gerkin, Richard D.; Boyer, Leslie V.

    2015-01-01

    Background. Crotalidae Polyvalent Immune Fab (Ovine) has been the only antivenom commercially available in the US since 2007 for treatment of Crotalinae envenomation. Late coagulopathy can occur or recur after clearance of Fab antivenom, often after hospital discharge, lasting in some cases more than 2 weeks. There have been serious, even fatal, bleeding complications associated with recurrence phenomena. Frequent follow-up is required, and additional intervention or hospitalization is often necessary. F(ab')2 immunoglobulin derivatives have longer plasma half life than do Fab. We hypothesized that F(ab')2 antivenom would be superior to Fab in the prevention of late coagulopathy following treatment of patients with Crotalinae envenomation. Methods. We conducted a prospective, double-blind, randomized clinical trial, comparing late coagulopathy in snakebitten patients treated with F(ab')2 with maintenance doses [F(ab')2/F(ab')2], or F(ab')2 with placebo maintenance doses [F(ab')2/placebo], versus Fab with maintenance doses [Fab/Fab]. The primary efficacy endpoint was coagulopathy (platelet count < 150 K/mm3, fibrinogen level < 150 mg/dL) between end of maintenance dosing and day 8. Results. 121 patients were randomized at 18 clinical sites and received at least one dose of study drug. 114 completed the study. Of these, 11/37 (29.7%) in the Fab/Fab cohort experienced late coagulopathy versus 4/39 (10.3%, p < 0.05) in the F(ab')2/F(ab')2 cohort and 2/38 (5.3%, p < 0.05) in the F(ab')2/placebo cohort. The lowest heterologous protein exposure was with F(ab')2/placebo. No serious adverse events were related to study drug. In each study arm, one patient experienced an acute serum reaction and one experienced serum sickness. Conclusions. In this study, management of coagulopathic Crotalinae envenomation with longer-half-life F(ab')2 antivenom, with or without maintenance dosing, reduced the risk of subacute coagulopathy and bleeding following treatment of envenomation. PMID:25361165

  16. Comparison of F(ab')2 versus Fab antivenom for pit viper envenomation: a prospective, blinded, multicenter, randomized clinical trial.

    PubMed

    Bush, Sean P; Ruha, Anne-Michelle; Seifert, Steven A; Morgan, David L; Lewis, Brandon J; Arnold, Thomas C; Clark, Richard F; Meggs, William J; Toschlog, Eric A; Borron, Stephen W; Figge, Gary R; Sollee, Dawn R; Shirazi, Farshad M; Wolk, Robert; de Chazal, Ives; Quan, Dan; García-Ubbelohde, Walter; Alagón, Alejandro; Gerkin, Richard D; Boyer, Leslie V

    2015-01-01

    Crotalidae Polyvalent Immune Fab (Ovine) has been the only antivenom commercially available in the US since 2007 for treatment of Crotalinae envenomation. Late coagulopathy can occur or recur after clearance of Fab antivenom, often after hospital discharge, lasting in some cases more than 2 weeks. There have been serious, even fatal, bleeding complications associated with recurrence phenomena. Frequent follow-up is required, and additional intervention or hospitalization is often necessary. F(ab')2 immunoglobulin derivatives have longer plasma half life than do Fab. We hypothesized that F(ab')2 antivenom would be superior to Fab in the prevention of late coagulopathy following treatment of patients with Crotalinae envenomation. We conducted a prospective, double-blind, randomized clinical trial, comparing late coagulopathy in snakebitten patients treated with F(ab')2 with maintenance doses [F(ab')2/F(ab')2], or F(ab')2 with placebo maintenance doses [F(ab')2/placebo], versus Fab with maintenance doses [Fab/Fab]. The primary efficacy endpoint was coagulopathy (platelet count < 150 K/mm(3), fibrinogen level < 150 mg/dL) between end of maintenance dosing and day 8. 121 patients were randomized at 18 clinical sites and received at least one dose of study drug. 114 completed the study. Of these, 11/37 (29.7%) in the Fab/Fab cohort experienced late coagulopathy versus 4/39 (10.3%, p < 0.05) in the F(ab')2/F(ab')2 cohort and 2/38 (5.3%, p < 0.05) in the F(ab')2/placebo cohort. The lowest heterologous protein exposure was with F(ab')2/placebo. No serious adverse events were related to study drug. In each study arm, one patient experienced an acute serum reaction and one experienced serum sickness. In this study, management of coagulopathic Crotalinae envenomation with longer-half-life F(ab')2 antivenom, with or without maintenance dosing, reduced the risk of subacute coagulopathy and bleeding following treatment of envenomation.

  17. 14 CFR 171.211 - Maintenance and operations requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Communications Commission's licensing requirements and show that he has the special knowledge and skills needed... persons only. (3) Federal Communications Commission's requirements for operating and maintenance personnel... Federal Communications Commission, and must not allow any modification to be made without specific...

  18. 14 CFR 171.211 - Maintenance and operations requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Communications Commission's licensing requirements and show that he has the special knowledge and skills needed... persons only. (3) Federal Communications Commission's requirements for operating and maintenance personnel... Federal Communications Commission, and must not allow any modification to be made without specific...

  19. 14 CFR 171.211 - Maintenance and operations requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Communications Commission's licensing requirements and show that he has the special knowledge and skills needed... persons only. (3) Federal Communications Commission's requirements for operating and maintenance personnel... Federal Communications Commission, and must not allow any modification to be made without specific...

  20. 14 CFR 171.211 - Maintenance and operations requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Communications Commission's licensing requirements and show that he has the special knowledge and skills needed... persons only. (3) Federal Communications Commission's requirements for operating and maintenance personnel... Federal Communications Commission, and must not allow any modification to be made without specific...

  1. 14 CFR 171.211 - Maintenance and operations requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Communications Commission's licensing requirements and show that he has the special knowledge and skills needed... persons only. (3) Federal Communications Commission's requirements for operating and maintenance personnel... Federal Communications Commission, and must not allow any modification to be made without specific...

  2. 14 CFR 147.17 - Instructional equipment requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (CONTINUED) SCHOOLS AND OTHER CERTIFICATED AGENCIES AVIATION MAINTENANCE TECHNICIAN SCHOOLS Certification... maintenance technician might be required to work and with which the technician should be familiar. (b) The...

  3. 43 CFR 3835.11 - What special filing and reporting requirements pertain to the different types of waivers?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... maintenance fee to maintain your claim during that assessment year; (iii) Assessment work was deferred for... MINERALS MANAGEMENT (3000) WAIVERS FROM ANNUAL MAINTENANCE FEES Filing Requirements § 3835.11 What special... the annual maintenance fee. (e) Contest actions. If the Secretary contests your mining claim or site...

  4. 43 CFR 3835.11 - What special filing and reporting requirements pertain to the different types of waivers?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... maintenance fee to maintain your claim during that assessment year; (iii) Assessment work was deferred for... MINERALS MANAGEMENT (3000) WAIVERS FROM ANNUAL MAINTENANCE FEES Filing Requirements § 3835.11 What special... the annual maintenance fee. (e) Contest actions. If the Secretary contests your mining claim or site...

  5. 43 CFR 3835.11 - What special filing and reporting requirements pertain to the different types of waivers?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... maintenance fee to maintain your claim during that assessment year; (iii) Assessment work was deferred for... MINERALS MANAGEMENT (3000) WAIVERS FROM ANNUAL MAINTENANCE FEES Filing Requirements § 3835.11 What special... the annual maintenance fee. (e) Contest actions. If the Secretary contests your mining claim or site...

  6. 43 CFR 3835.11 - What special filing and reporting requirements pertain to the different types of waivers?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... maintenance fee to maintain your claim during that assessment year; (iii) Assessment work was deferred for... MINERALS MANAGEMENT (3000) WAIVERS FROM ANNUAL MAINTENANCE FEES Filing Requirements § 3835.11 What special... the annual maintenance fee. (e) Contest actions. If the Secretary contests your mining claim or site...

  7. Space station orbit maintenance

    NASA Technical Reports Server (NTRS)

    Kaplan, D. I.; Jones, R. M.

    1983-01-01

    The orbit maintenance problem is examined for two low-earth-orbiting space station concepts - the large, manned Space Operations Center (SOC) and the smaller, unmanned Science and Applications Space Platform (SASP). Atmospheric drag forces are calculated, and circular orbit altitudes are selected to assure a 90 day decay period in the event of catastrophic propulsion system failure. Several thrusting strategies for orbit maintenance are discussed. Various chemical and electric propulsion systems for orbit maintenance are compared on the basis of propellant resupply requirements, power requirements, Shuttle launch costs, and technology readiness.

  8. 14 CFR 147.19 - Materials, special tools, and shop equipment requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., DEPARTMENT OF TRANSPORTATION (CONTINUED) SCHOOLS AND OTHER CERTIFICATED AGENCIES AVIATION MAINTENANCE TECHNICIAN SCHOOLS Certification Requirements § 147.19 Materials, special tools, and shop equipment requirements. An applicant for an aviation maintenance technician school certificate and rating, or for an...

  9. Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis

    PubMed Central

    Jacob, Bindya; Yamashita, Namiko; Wang, Chelsia Qiuxia; Taniuchi, Ichiro; Littman, Dan R.; Asou, Norio

    2010-01-01

    The RUNX1/AML1 gene is the most frequently mutated gene in human leukemia. Conditional deletion of Runx1 in adult mice results in an increase of hematopoietic stem cells (HSCs), which serve as target cells for leukemia; however, Runx1−/− mice do not develop spontaneous leukemia. Here we show that maintenance of Runx1−/− HSCs is compromised, progressively resulting in HSC exhaustion. In leukemia development, the stem cell exhaustion was rescued by additional genetic changes. Retroviral insertional mutagenesis revealed Evi5 activation as a cooperating genetic alteration and EVI5 overexpression indeed prevented Runx1−/− HSC exhaustion in mice. Moreover, EVI5 was frequently overexpressed in human RUNX1-related leukemias. These results provide insights into the mechanism for maintenance of pre-leukemic stem cells and may provide a novel direction for therapeutic applications. PMID:20008790

  10. The impact of climate change on transportation in the gulf coast

    USGS Publications Warehouse

    Savonis, M.J.; Burkett, V.R.; Potter, J.R.; Kafalenos, R.; Hyman, R.; Leonard, K.

    2009-01-01

    Climate affects the design, construction, safety, operations, and maintenance of transportation infrastructure and systems. The prospect of a changing climate raises critical questions regarding how alterations in temperature, precipitation, storm events, and other aspects of the climate could affect the nation's transportation system. This regional assessment of climate change and its potential impacts on transportation systems addresses these questions for the central Gulf Coast between Houston and Mobile. Warming temperatures are likely to increase the costs of transportation construction, maintenance, and operations. More frequent extreme precipitation events will likely disrupt transportation networks with flooding and visibility problems. Relative sea level rise will make much of the existing infrastructure more prone to frequent or permanent inundation. Increased storm intensity may lead to increased service disruption and damage. Consideration of these factors in today's transportation decisions should lead to a more robust, resilient, and cost-effective transportation network in the coming decades. ?? 2009 ASCE.

  11. 14 CFR 171.11 - Maintenance and operations requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Communications Commission's licensing requirements and show that he has the special knowledge and skills needed... maintenance procedures and servicing guides stating the frequency of servicing. (8) Air-ground communications...

  12. 14 CFR 171.11 - Maintenance and operations requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Communications Commission's licensing requirements and show that he has the special knowledge and skills needed... maintenance procedures and servicing guides stating the frequency of servicing. (8) Air-ground communications...

  13. 14 CFR 171.11 - Maintenance and operations requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Communications Commission's licensing requirements and show that he has the special knowledge and skills needed... maintenance procedures and servicing guides stating the frequency of servicing. (8) Air-ground communications...

  14. Cryogenics maintenance strategy

    NASA Astrophysics Data System (ADS)

    Cruzat, Fabiola

    2012-09-01

    ALMA is an interferometer composed of 66 independent systems, with specific maintenance requirements for each subsystem. To optimize the observation time and reduce downtime maintenance, requirements are very demanding. One subsystem with high maintenance efforts is cryogenics and vacuum. To organize the maintenance, the Cryogenic and Vacuum department is using and implementing different tools. These are monitoring and problem reporting systems and CMMS. This leads to different maintenance approaches: Preventive Maintenance, Corrective Maintenance and Condition Based Maintenance. In order to coordinate activities with other departments the preventive maintenance schedule is kept as flexible as systems allow. To cope with unavoidable failures, the team has to be prepared to work under any condition with the spares on time. Computerized maintenance management system (CMMS) will help to manage inventory control for reliable spare part handling, the correct record of work orders and traceability of maintenance activities. For an optimized approach the department is currently evaluating where preventive or condition based maintenance applies to comply with the individual system demand. Considering the change from maintenance contracts to in-house maintenance will help to minimize costs and increase availability of parts. Due to increased number of system and tasks the cryo team needs to grow. Training of all staff members is mandatory, in depth knowledge must be built up by doing complex maintenance activities in the Cryo group, use of advanced computerized metrology systems.

  15. Design considerations and rationale of a multi-center trial to sustain weight loss: the Weight Loss Maintenance Trial.

    PubMed

    Brantley, Phillip; Appel, Lawrence; Hollis, Jack; Stevens, Victor; Ard, Jamy; Champagne, Catherine; Elmer, Patricia; Harsha, David; Myers, Valerie; Proschan, Michael; William, Vollmer; Svetkey, Laura

    2008-01-01

    The Weight Loss Maintenance Trial (WLM) is a multi-center, randomized, controlled trial that compares the effects of two 30-month maintenance interventions, i.e., Personal Contact (PC) and Interactive Technology (IT) to a self-directed usual care control group (SD), in overweight or obese individuals who are at high risk for cardiovascular disease. This paper provides an overview of the design and methods, and design considerations and lessons learned from this trial. All participants received a 6-month behavioral weight loss program consisting of weekly group sessions. Participants who lost 4 kg were randomized to one of three conditions (PC, IT, or SD). The PC condition provided monthly contacts with an interventionist primarily via telephone and quarterly face-to-face visits. The IT condition provided frequent, individualized contact through a tailored, website system. Both the PC and IT maintenance programs encouraged the DASH dietary pattern and employed theory-based behavioral techniques to promote maintenance. Design considerations included choice of study population, frequency and type of intervention visits, and choice of primary outcome. Overweight or obese persons with CVD risk factors were studied. The pros and cons of studying this population while excluding others are presented. We studied intervention contact strategies that made fewer demands on participant time and travel, while providing frequent opportunities for interaction. The primary outcome variable for the trial was change in weight from randomization to end of follow-up (30 months). Limits to generalizability are discussed. Individuals in need of weight loss strategies may have been excluded due to barriers associated with internet use. Other participants may have been excluded secondary to a comorbid condition. This paper highlights the design and methods of WLM and informs readers of discussions of critical issues and lessons learned from the trial.

  16. Histone deacetylase 3 is required for maintenance of bone mass during aging

    PubMed Central

    McGee-Lawrence, Meghan E.; Bradley, Elizabeth W.; Dudakovic, Amel; Carlson, Samuel W.; Ryan, Zachary C.; Kumar, Rajiv; Dadsetan, Mahrokh; Yaszemski, Michael J.; Chen, Qingshan; An, Kai-Nan; Westendorf, Jennifer J.

    2012-01-01

    Histone deacetylase 3 (Hdac3) is a nuclear enzyme that removes acetyl groups from lysine residues in histones and other proteins to epigenetically regulate gene expression. Hdac3 interacts with bone-related transcription factors and co-factors such as Runx2 and Zfp521, and thus is poised to play a key role in the skeletal system. To understand the role of Hdac3 in osteoblasts and osteocytes, Hdac3 conditional knockout (CKO) mice were created with the Osteocalcin (OCN) promoter driving Cre expression. Hdac3 CKOOCN mice were of normal size and weight, but progressively lost trabecular and cortical bone mass with age. The Hdac3 CKOOCN mice exhibited reduced cortical bone mineralization and material properties and suffered frequent fractures. Bone resorption was lower, not higher, in the Hdac3 CKOOCN mice, suggesting that primary defects in osteoblasts caused the reduced bone mass. Indeed, reductions in bone formation were observed. Osteoblasts and osteocytes from Hdac3 CKOOCN mice showed increased DNA damage and reduced functional activity in vivo and in vitro. Thus, Hdac3 expression in osteoblasts and osteocytes is essential for bone maintenance during aging. PMID:23085085

  17. Health maintenance organizations: organizational structure and services--HCFA. Correction notice.

    PubMed

    1993-09-03

    This document corrects regulatory citations in the preamble of a notice of proposed rulemaking that we issued in the Federal Register on July 15, 1993 (56 FR 38170). The notice proposed to amend the HCFA regulations governing requirements for health maintenance organizations that are Federally qualified (FQHMOs) to incorporate changes made by the Health Maintenance Organization Amendments of 1988 pertaining to the definition of an FQHMO, requirements for providing physician services as basic health services, and requirements for fiscal soundness and insolvency protection.

  18. Antibody-secreting cells in respiratory tract tissues in the absence of eosinophils as supportive partners.

    PubMed

    Sealy, Robert E; Surman, Sherri L; Vogel, Peter; Hurwitz, Julia L

    2016-11-01

    Antibody-secreting cells (ASCs) in respiratory tract tissues provide a first line of defense against invading pathogens. These cells often secrete IgA that is efficiently transcytosed across epithelial barriers into the airway lumen where pathogens can be blocked at their point of entry. Previous literature has reported that in the bone marrow, eosinophils are required for the maintenance of ASCs, and that eosinophils co-localize with ASCs as nearest neighbors. To determine if these rules similarly apply to the maintenance of ASCs in respiratory tract tissues, we evaluated virus-specific responses 1 month and 4 months following an intranasal virus infection of eosinophil-null (∆dblGATA-1) mice. Results showed that ASCs were fractionally reduced, but were nonetheless observed in respiratory tract tissues in the absence of eosinophils. Virus-specific antibodies were similarly observed in the airways of eosinophil-deficient mice. Respiratory tract ASCs were also present in mice lacking neutrophils (Mcl1 ∆M ). The staining of tissue sections from the upper respiratory tract of wild-type mice following viral infections demonstrated that virus-specific ASCs were most frequently situated adjacent to epithelial cells rather than eosinophils or neutrophils. Taken together, these data emphasize that rules for cell maintenance are not absolute and that ASCs can survive in the respiratory tract without eosinophils or neutrophils as their nearest neighbors. © The Japanese Society for Immunology. 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  19. Technical information report: Plasma melter operation, reliability, and maintenance analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hendrickson, D.W.

    1995-03-14

    This document provides a technical report of operability, reliability, and maintenance of a plasma melter for low-level waste vitrification, in support of the Hanford Tank Waste Remediation System (TWRS) Low-Level Waste (LLW) Vitrification Program. A process description is provided that minimizes maintenance and downtime and includes material and energy balances, equipment sizes and arrangement, startup/operation/maintence/shutdown cycle descriptions, and basis for scale-up to a 200 metric ton/day production facility. Operational requirements are provided including utilities, feeds, labor, and maintenance. Equipment reliability estimates and maintenance requirements are provided which includes a list of failure modes, responses, and consequences.

  20. Impact of microbial efficiency to predict MP supply when estimating protein requirements of growing beef cattle from performance.

    PubMed

    Watson, A K; Klopfenstein, T J; Erickson, G E; MacDonald, J C; Wilkerson, V A

    2017-07-01

    Data from 16 trials were compiled to calculate microbial CP (MCP) production and MP requirements of growing cattle on high-forage diets. All cattle were individually fed diets with 28% to 72% corn cobs in addition to either alfalfa, corn silage, or sorghum silage at 18% to 60% of the diet (DM basis). The remainder of the diet consisted of protein supplement. Source of protein within the supplement varied and included urea, blood meal, corn gluten meal, dry distillers grains, feather meal, meat and bone meal, poultry by-product meal, soybean meal, and wet distillers grains. All trials included a urea-only treatment. Intake of all cattle within an experiment was held constant, as a percentage of BW, established by the urea-supplemented group. In each trial the base diet (forage and urea supplement) was MP deficient. Treatments consisted of increasing amounts of test protein replacing the urea supplement. As protein in the diet increased, ADG plateaued. Among experiments, ADG ranged from 0.11 to 0.73 kg. Three methods of calculating microbial efficiency were used to determine MP supply. Gain was then regressed against calculated MP supply to determine MP requirement for maintenance and gain. Method 1 (based on a constant 13% microbial efficiency as used by the beef NRC model) predicted an MP maintenance requirement of 3.8 g/kg BW and 385 g MP/kg gain. Method 2 calculated microbial efficiency using low-quality forage diets and predicted MP requirements of 3.2 g/kg BW for maintenance and 448 g/kg for gain. Method 3 (based on an equation predicting MCP yield from TDN intake, proposed by the Beef Cattle Nutrient Requirements Model [BCNRM]) predicted MP requirements of 3.1 g/kg BW for maintenance and 342 g/kg for gain. The factorial method of calculating MP maintenance requirements accounts for scurf, endogenous urinary, and metabolic fecal protein losses and averaged 4.2 g/kg BW. Cattle performance data demonstrate formulating diets to meet the beef NRC model recommended MP maintenance requirement (3.8 g/kg S) works well when using 13% microbial efficiency. Therefore, a change in how microbial efficiency is calculated necessitates a change in the proposed MP maintenance requirement to not oversupply or undersupply RUP. Using the 2016 BCNRM to predict MCP production and formulate diets to meet MP requirements also requires changing the MP maintenance requirement to 3.1 g/kg BW.

  1. Maintainability Program Requirements for Space Systems

    NASA Technical Reports Server (NTRS)

    1987-01-01

    This document is established to provide common general requirements for all NASA programs to: design maintainability into all systems where maintenance is a factor in system operation and mission success; and ensure that maintainability characteristics are developed through the systems engineering process. These requirements are not new. Design for ease of maintenance and minimization of repair time have always been fundamental requirements of the systems engineering process. However, new or reusable orbital manned and in-flight maintainable unmanned space systems demand special emphasis on maintainability, and this document has been prepared to meet that need. Maintainability requirements on many NASA programs differ in phasing and task emphasis from requirements promulgated by other Government agencies. This difference is due to the research and development nature of NASA programs where quantities produced are generally small; therefore, the depth of logistics support typical of many programs is generally not warranted. The cost of excessive maintenance is very high due to the logistics problems associated with the space environment. The ability to provide timely maintenance often involves safety considerations for manned space flight applications. This document represents a basic set of requirements that will achieve a design for maintenance. These requirements are directed primarily at manned and unmanned orbital space systems. To be effective, maintainability requirements should be tailored to meet specific NASA program and project needs and constraints. NASA activities shall invoke the requirements of this document consistent with program planning in procurements or on inhouse development efforts.

  2. 33 CFR 150.503 - What are the time interval requirements for maintenance on survival craft falls?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... requirements for maintenance on survival craft falls? 150.503 Section 150.503 Navigation and Navigable Waters... maintenance on survival craft falls? (a) Each fall used in a launching device for survival craft or rescue boats must be turned end-for-end at intervals of not more than 30 months. (b) Each fall must be replaced...

  3. 33 CFR 150.503 - What are the time interval requirements for maintenance on survival craft falls?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... requirements for maintenance on survival craft falls? 150.503 Section 150.503 Navigation and Navigable Waters... maintenance on survival craft falls? (a) Each fall used in a launching device for survival craft or rescue boats must be turned end-for-end at intervals of not more than 30 months. (b) Each fall must be replaced...

  4. 33 CFR 150.503 - What are the time interval requirements for maintenance on survival craft falls?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... requirements for maintenance on survival craft falls? 150.503 Section 150.503 Navigation and Navigable Waters... maintenance on survival craft falls? (a) Each fall used in a launching device for survival craft or rescue boats must be turned end-for-end at intervals of not more than 30 months. (b) Each fall must be replaced...

  5. 33 CFR 150.503 - What are the time interval requirements for maintenance on survival craft falls?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... requirements for maintenance on survival craft falls? 150.503 Section 150.503 Navigation and Navigable Waters... maintenance on survival craft falls? (a) Each fall used in a launching device for survival craft or rescue boats must be turned end-for-end at intervals of not more than 30 months. (b) Each fall must be replaced...

  6. 33 CFR 150.503 - What are the time interval requirements for maintenance on survival craft falls?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... requirements for maintenance on survival craft falls? 150.503 Section 150.503 Navigation and Navigable Waters... maintenance on survival craft falls? (a) Each fall used in a launching device for survival craft or rescue boats must be turned end-for-end at intervals of not more than 30 months. (b) Each fall must be replaced...

  7. 14 CFR 171.115 - Maintenance and operations requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Maintenance and operations requirements. 171.115 Section 171.115 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... meet at a minimum the Federal Communications Commission's licensing requirements and show that he has...

  8. 14 CFR 171.115 - Maintenance and operations requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Maintenance and operations requirements. 171.115 Section 171.115 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... meet at a minimum the Federal Communications Commission's licensing requirements and show that he has...

  9. 14 CFR 171.115 - Maintenance and operations requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Maintenance and operations requirements. 171.115 Section 171.115 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... meet at a minimum the Federal Communications Commission's licensing requirements and show that he has...

  10. 14 CFR 171.115 - Maintenance and operations requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Maintenance and operations requirements. 171.115 Section 171.115 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... meet at a minimum the Federal Communications Commission's licensing requirements and show that he has...

  11. 14 CFR 171.115 - Maintenance and operations requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Maintenance and operations requirements. 171.115 Section 171.115 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... meet at a minimum the Federal Communications Commission's licensing requirements and show that he has...

  12. 14 CFR 135.427 - Manual requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... overall responsibility for the management of both the required inspection functions and the other maintenance, preventive maintenance, and alterations functions. (9) Procedures to ensure that required... retrievable in the English language. [Doc. No. 16097, 43 FR 46783, Oct. 10, 1978, as amended by Amdt. 135-66...

  13. 43 CFR 4750.3 - Application requirements for private maintenance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR RANGE MANAGEMENT (4000) PROTECTION, MANAGEMENT, AND CONTROL OF WILD FREE-ROAMING HORSES AND BURROS Private Maintenance § 4750.3 Application requirements for...

  14. 43 CFR 4750.3 - Application requirements for private maintenance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR RANGE MANAGEMENT (4000) PROTECTION, MANAGEMENT, AND CONTROL OF WILD FREE-ROAMING HORSES AND BURROS Private Maintenance § 4750.3 Application requirements for...

  15. 43 CFR 4750.3 - Application requirements for private maintenance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR RANGE MANAGEMENT (4000) PROTECTION, MANAGEMENT, AND CONTROL OF WILD FREE-ROAMING HORSES AND BURROS Private Maintenance § 4750.3 Application requirements for...

  16. 43 CFR 4750.3 - Application requirements for private maintenance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR RANGE MANAGEMENT (4000) PROTECTION, MANAGEMENT, AND CONTROL OF WILD FREE-ROAMING HORSES AND BURROS Private Maintenance § 4750.3 Application requirements for...

  17. Crew considerations in the design for Space Station Freedom modules on-orbit maintenance

    NASA Technical Reports Server (NTRS)

    Stokes, Jack W.; Williams, Katherine A.

    1992-01-01

    The paper presents an approach to the maintenance process currently planned for the Space Station Freedom modules. In particular, it describes the planned crew interfaces with maintenance items, and the anticipated implications for the crew in performing the interior and exterior maintenance of modules developed by U.S., ESA, and NASDA. Special consideration is given to the maintenance requirements, allocations, and approach; the maintenance design; the Maintenance Workstation; the robotic mechanisms; and the developemnt of maintenance techniques.

  18. 48 CFR 217.171 - Multiyear contracts for services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... agency may enter into multiyear contracts for supplies and services required for management, maintenance..., maintenance, and support of facilities and installations. (ii) Maintenance or modification of aircraft, ships... services (e.g., ground maintenance, in-plane refueling, bus transportation, and refuse collection and...

  19. 45 CFR 149.350 - Maintenance of records.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... REQUIREMENTS FOR THE EARLY RETIREE REINSURANCE PROGRAM Reimbursement Methods § 149.350 Maintenance of records..., or longer if otherwise required by law. (b) The records that must be retained are as follows— (1) All...

  20. 45 CFR 149.350 - Maintenance of records.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... REQUIREMENTS FOR THE EARLY RETIREE REINSURANCE PROGRAM Reimbursement Methods § 149.350 Maintenance of records..., or longer if otherwise required by law. (b) The records that must be retained are as follows— (1) All...

  1. 45 CFR 149.350 - Maintenance of records.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... REQUIREMENTS FOR THE EARLY RETIREE REINSURANCE PROGRAM Reimbursement Methods § 149.350 Maintenance of records..., or longer if otherwise required by law. (b) The records that must be retained are as follows— (1) All...

  2. 30 CFR 49.6 - Equipment and maintenance requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... TRAINING MINE RESCUE TEAMS § 49.6 Equipment and maintenance requirements. (a) Each mine rescue station..., applicable to the supplied breathing apparatus and sufficient to sustain each team for eight hours while...

  3. 30 CFR 49.6 - Equipment and maintenance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... TRAINING MINE RESCUE TEAMS § 49.6 Equipment and maintenance requirements. (a) Each mine rescue station..., applicable to the supplied breathing apparatus and sufficient to sustain each team for eight hours while...

  4. Energy Consumption of Die Casting Operations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jerald Brevick; clark Mount-Campbell; Carroll Mobley

    2004-03-15

    Molten metal processing is inherently energy intensive and roughly 25% of the cost of die-cast products can be traced to some form of energy consumption [1]. The obvious major energy requirements are for melting and holding molten alloy in preparation for casting. The proper selection and maintenance of melting and holding equipment are clearly important factors in minimizing energy consumption in die-casting operations [2]. In addition to energy consumption, furnace selection also influences metal loss due to oxidation, metal quality, and maintenance requirements. Other important factors influencing energy consumption in a die-casting facility include geographic location, alloy(s) cast, starting formmore » of alloy (solid or liquid), overall process flow, casting yield, scrap rate, cycle times, number of shifts per day, days of operation per month, type and size of die-casting form of alloy (solid or liquid), overall process flow, casting yield, scrap rate, cycle times, number of shifts per day, days of operation per month, type and size of die-casting machine, related equipment (robots, trim presses), and downstream processing (machining, plating, assembly, etc.). Each of these factors also may influence the casting quality and productivity of a die-casting enterprise. In a die-casting enterprise, decisions regarding these issues are made frequently and are based on a large number of factors. Therefore, it is not surprising that energy consumption can vary significantly from one die-casting enterprise to the next, and within a single enterprise as function of time.« less

  5. Computer-aided acquisition and logistics support (CALS): Concept of Operations for Depot Maintenance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bourgeois, N.C.; Greer, D.K.

    1993-04-01

    This CALS Concept of Operations for Depot Maintenance provides the foundation strategy and the near term tactical plan for CALS implementation in the depot maintenance environment. The user requirements enumerated and the overarching architecture outlined serve as the primary framework for implementation planning. The seamless integration of depot maintenance business processes and supporting information systems with the emerging global CALS environment will be critical to the efficient realization of depot user's information requirements, and as, such will be a fundamental theme in depot implementations.

  6. Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis.

    PubMed

    He, J; Cooper, H M; Reyes, A; Di Re, M; Sembongi, H; Litwin, T R; Gao, J; Neuman, K C; Fearnley, I M; Spinazzola, A; Walker, J E; Holt, I J

    2012-07-01

    Mitochondrial ribosomes and translation factors co-purify with mitochondrial nucleoids of human cells, based on affinity protein purification of tagged mitochondrial DNA binding proteins. Among the most frequently identified proteins were ATAD3 and prohibitin, which have been identified previously as nucleoid components, using a variety of methods. Both proteins are demonstrated to be required for mitochondrial protein synthesis in human cultured cells, and the major binding partner of ATAD3 is the mitochondrial ribosome. Altered ATAD3 expression also perturbs mtDNA maintenance and replication. These findings suggest an intimate association between nucleoids and the machinery of protein synthesis in mitochondria. ATAD3 and prohibitin are tightly associated with the mitochondrial membranes and so we propose that they support nucleic acid complexes at the inner membrane of the mitochondrion.

  7. A computer-based maintenance reminder and record-keeping system for clinical laboratories.

    PubMed

    Roberts, B I; Mathews, C L; Walton, C J; Frazier, G

    1982-09-01

    "Maintenance" is all the activity an organization devotes to keeping instruments within performance specifications to assure accurate and precise operation. The increasing use of complex analytical instruments as "workhorses" in clinical laboratories requires more maintenance awareness by laboratory personnel. Record-keeping systems that document maintenance completion and that should prompt the continued performance of maintenance tasks have not kept up with instrumentation development. We report here a computer-based record-keeping and reminder system that lists weekly the maintenance items due for each work station in the laboratory, including the time required to complete each item. Written in BASIC, the system uses a DATABOSS data base management system running on a time-shared Digital Equipment Corporation PDP 11/60 computer with a RSTS V 7.0 operating system.

  8. Monitoring asthma in childhood: symptoms, exacerbations and quality of life.

    PubMed

    Brand, Paul L P; Mäkelä, Mika J; Szefler, Stanley J; Frischer, Thomas; Price, David

    2015-06-01

    Monitoring asthma in children in clinical practice is primarily performed by reviewing disease activity (daytime and night-time symptoms, use of reliever medication, exacerbations requiring frequent use of reliever medication and urgent visits to the healthcare professional) and the impact of the disease on children's daily activities, including sports and play, in a clinical interview. In such an interview, most task force members also discuss adherence to maintenance therapy and the patients' (and parents') views and beliefs on the goals of treatment and the amount of treatment required to achieve those goals. Composite asthma control and quality of life measures, although potentially useful in research, have limited value in clinical practice because they have a short recall window and do not cover the entire spectrum of asthma control. Telemonitoring of children with asthma cannot replace face-to-face follow-up and monitoring because there is no evidence that it is associated with improved health outcomes. Copyright ©ERS 2015.

  9. Laboratory services series: a programmed maintenance system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tuxbury, D.C.; Srite, B.E.

    1980-01-01

    The diverse facilities, operations and equipment at a major national research and development laboratory require a systematic, analytical approach to operating equipment maintenance. A computer-scheduled preventive maintenance program is described including program development, equipment identification, maintenance and inspection instructions, scheduling, personnel, and equipment history.

  10. RecFOR Is Not Required for Pneumococcal Transformation but Together with XerS for Resolution of Chromosome Dimers Frequently Formed in the Process

    PubMed Central

    Johnston, Calum; Mortier-Barrière, Isabelle; Granadel, Chantal; Polard, Patrice; Martin, Bernard; Claverys, Jean-Pierre

    2015-01-01

    Homologous recombination (HR) is required for both genome maintenance and generation of diversity in eukaryotes and prokaryotes. This process initiates from single-stranded (ss) DNA and is driven by a universal recombinase, which promotes strand exchange between homologous sequences. The bacterial recombinase, RecA, is loaded onto ssDNA by recombinase loaders, RecBCD and RecFOR for genome maintenance. DprA was recently proposed as a third loader dedicated to genetic transformation. Here we assessed the role of RecFOR in transformation of the human pathogen Streptococcus pneumoniae. We firstly established that RecFOR proteins are not required for plasmid transformation, strongly suggesting that DprA ensures annealing of plasmid single-strands internalized in the process. We then observed no reduction in chromosomal transformation using a PCR fragment as donor, contrasting with the 10,000-fold drop in dprA - cells and demonstrating that RecFOR play no role in transformation. However, a ∼1.45-fold drop in transformation was observed with total chromosomal DNA in recFOR mutants. To account for this limited deficit, we hypothesized that transformation with chromosomal DNA stimulated unexpectedly high frequency (>30% of cells) formation of chromosome dimers as an intermediate in the generation of tandem duplications, and that RecFOR were crucial for dimer resolution. We validated this hypothesis, showing that the site-specific recombinase XerS was also crucial for dimer resolution. An even higher frequency of dimer formation (>80% of cells) was promoted by interspecies transformation with Streptococcus mitis chromosomal DNA, which contains numerous inversions compared to pneumococcal chromosome, each potentially promoting dimerization. In the absence of RecFOR and XerS, dimers persist, as confirmed by DAPI staining, and can limit the efficiency of transformation, since resulting in loss of transformant chromosome. These findings strengthen the view that different HR machineries exist for genome maintenance and transformation in pneumococci. These observations presumably apply to most naturally transformable species. PMID:25569614

  11. 76 FR 43906 - Approval and Promulgation of State Implementation Plan Revisions; Infrastructure Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... emissions inventories, monitoring, and modeling, to assure attainment and maintenance of the standards... NAAQS required the deployment of a system of new monitors to measure ambient levels of that new... requirements, including emissions inventories, monitoring, and modeling to assure attainment and maintenance of...

  12. 40 CFR 63.1572 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 13 2013-07-01 2012-07-01 true What are my monitoring installation... Compliance Requirements § 63.1572 What are my monitoring installation, operation, and maintenance requirements? (a) You must install, operate, and maintain each continuous emission monitoring system according...

  13. 40 CFR 63.1572 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 12 2011-07-01 2009-07-01 true What are my monitoring installation... Requirements § 63.1572 What are my monitoring installation, operation, and maintenance requirements? (a) You must install, operate, and maintain each continuous emission monitoring system according to the...

  14. 40 CFR 63.1572 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 13 2014-07-01 2014-07-01 false What are my monitoring installation... Compliance Requirements § 63.1572 What are my monitoring installation, operation, and maintenance requirements? (a) You must install, operate, and maintain each continuous emission monitoring system according...

  15. March 10, 2006, Transportation Conformity Rule That Addresses Requirements for Project-level Conformity Determinations in PM2.5 and PM10 Nonattainment and Maintenance Areas

    EPA Pesticide Factsheets

    This final rule, published March 10, 2006, establishes requirements for project-level conformity determinations in particulate matter (PM) 2.5 nonattainment and maintenance areas, and revises existing requirements for projects in PM10 areas.

  16. 30 CFR 75.506-1 - Electric face equipment; permissible condition; maintenance requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Electric face equipment; permissible condition... Equipment-General § 75.506-1 Electric face equipment; permissible condition; maintenance requirements. (a) Except as provided in paragraph (b) of this section, electric face equipment which meets the requirements...

  17. 30 CFR 75.506-1 - Electric face equipment; permissible condition; maintenance requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Electric face equipment; permissible condition... Equipment-General § 75.506-1 Electric face equipment; permissible condition; maintenance requirements. (a) Except as provided in paragraph (b) of this section, electric face equipment which meets the requirements...

  18. 30 CFR 75.506-1 - Electric face equipment; permissible condition; maintenance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Electric face equipment; permissible condition... Equipment-General § 75.506-1 Electric face equipment; permissible condition; maintenance requirements. (a) Except as provided in paragraph (b) of this section, electric face equipment which meets the requirements...

  19. 30 CFR 75.506-1 - Electric face equipment; permissible condition; maintenance requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Electric face equipment; permissible condition... Equipment-General § 75.506-1 Electric face equipment; permissible condition; maintenance requirements. (a) Except as provided in paragraph (b) of this section, electric face equipment which meets the requirements...

  20. 30 CFR 75.506-1 - Electric face equipment; permissible condition; maintenance requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Electric face equipment; permissible condition... Equipment-General § 75.506-1 Electric face equipment; permissible condition; maintenance requirements. (a) Except as provided in paragraph (b) of this section, electric face equipment which meets the requirements...

  1. 40 CFR 63.6125 - What are my monitor installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Stationary Combustion Turbines Testing and Initial Compliance Requirements § 63.6125 What are my monitor installation, operation, and maintenance requirements? (a) If you are operating a stationary combustion turbine... emission control device, you must monitor on a continuous basis your catalyst inlet temperature in order to...

  2. 33 CFR 150.508 - What are the maintenance and repair requirements for inflatable rescue boats?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... repair requirements for inflatable rescue boats? 150.508 Section 150.508 Navigation and Navigable Waters... repair requirements for inflatable rescue boats? The operator must perform the maintenance and repair of inflatable rescue boats according to the manufacturer's instructions. Operational Tests and Inspections...

  3. 33 CFR 150.508 - What are the maintenance and repair requirements for inflatable rescue boats?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... repair requirements for inflatable rescue boats? 150.508 Section 150.508 Navigation and Navigable Waters... repair requirements for inflatable rescue boats? The operator must perform the maintenance and repair of inflatable rescue boats according to the manufacturer's instructions. Operational Tests and Inspections...

  4. 33 CFR 150.508 - What are the maintenance and repair requirements for inflatable rescue boats?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... repair requirements for inflatable rescue boats? 150.508 Section 150.508 Navigation and Navigable Waters... repair requirements for inflatable rescue boats? The operator must perform the maintenance and repair of inflatable rescue boats according to the manufacturer's instructions. Operational Tests and Inspections...

  5. 33 CFR 150.508 - What are the maintenance and repair requirements for inflatable rescue boats?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... repair requirements for inflatable rescue boats? 150.508 Section 150.508 Navigation and Navigable Waters... repair requirements for inflatable rescue boats? The operator must perform the maintenance and repair of inflatable rescue boats according to the manufacturer's instructions. Operational Tests and Inspections...

  6. 33 CFR 150.508 - What are the maintenance and repair requirements for inflatable rescue boats?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... repair requirements for inflatable rescue boats? 150.508 Section 150.508 Navigation and Navigable Waters... repair requirements for inflatable rescue boats? The operator must perform the maintenance and repair of inflatable rescue boats according to the manufacturer's instructions. Operational Tests and Inspections...

  7. Space shuttle maintenance program planning document

    NASA Technical Reports Server (NTRS)

    Brown, D. V.

    1972-01-01

    A means for developing a space shuttle maintenance program which will be acceptable to the development centers, the operators (KSC and AF), and the manufacturer is presented. The general organization and decision processes for determining the essential scheduled maintenance requirements for the space shuttle orbiter are outlined. The development of initial scheduled maintenance programs is discussed. The remaining maintenance, that is non-scheduled or non-routine maintenance, is directed by the findings of the scheduled maintenance program and the normal operation of the shuttle. The remaining maintenance consists of maintenance actions to correct discrepancies noted during scheduled maintenance tasks, nonscheduled maintenance, normal operation, or condition monitoring.

  8. Management Tools for Bus Maintenance: Current Practices and New Methods. Final Report.

    ERIC Educational Resources Information Center

    Foerster, James; And Others

    Management of bus fleet maintenance requires systematic recordkeeping, management reporting, and work scheduling procedures. Tools for controlling and monitoring routine maintenance activities are in common use. These include defect and fluid consumption reports, work order systems, historical maintenance records, and performance and cost…

  9. 30 CFR 57.14105 - Procedures during repairs or maintenance.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... MINES Machinery and Equipment Safety Devices and Maintenance Requirements § 57.14105 Procedures during repairs or maintenance. Repairs or maintenance on machinery or equipment shall be performed only after the power is off, and the machinery or equipment blocked against hazardous motion. Machinery or equipment...

  10. 30 CFR 57.14105 - Procedures during repairs or maintenance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... MINES Machinery and Equipment Safety Devices and Maintenance Requirements § 57.14105 Procedures during repairs or maintenance. Repairs or maintenance on machinery or equipment shall be performed only after the power is off, and the machinery or equipment blocked against hazardous motion. Machinery or equipment...

  11. 30 CFR 56.14105 - Procedures during repairs or maintenance.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Machinery and Equipment Safety Devices and Maintenance Requirements § 56.14105 Procedures during repairs or maintenance. Repairs or maintenance of machinery or equipment shall be performed only after the power is off, and the machinery or equipment blocked against hazardous motion. Machinery or equipment motion or...

  12. 30 CFR 57.14105 - Procedures during repairs or maintenance.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... MINES Machinery and Equipment Safety Devices and Maintenance Requirements § 57.14105 Procedures during repairs or maintenance. Repairs or maintenance on machinery or equipment shall be performed only after the power is off, and the machinery or equipment blocked against hazardous motion. Machinery or equipment...

  13. 30 CFR 56.14105 - Procedures during repairs or maintenance.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Machinery and Equipment Safety Devices and Maintenance Requirements § 56.14105 Procedures during repairs or maintenance. Repairs or maintenance of machinery or equipment shall be performed only after the power is off, and the machinery or equipment blocked against hazardous motion. Machinery or equipment motion or...

  14. 30 CFR 57.14105 - Procedures during repairs or maintenance.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... MINES Machinery and Equipment Safety Devices and Maintenance Requirements § 57.14105 Procedures during repairs or maintenance. Repairs or maintenance on machinery or equipment shall be performed only after the power is off, and the machinery or equipment blocked against hazardous motion. Machinery or equipment...

  15. 30 CFR 56.14105 - Procedures during repairs or maintenance.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Machinery and Equipment Safety Devices and Maintenance Requirements § 56.14105 Procedures during repairs or maintenance. Repairs or maintenance of machinery or equipment shall be performed only after the power is off, and the machinery or equipment blocked against hazardous motion. Machinery or equipment motion or...

  16. 30 CFR 56.14105 - Procedures during repairs or maintenance.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Machinery and Equipment Safety Devices and Maintenance Requirements § 56.14105 Procedures during repairs or maintenance. Repairs or maintenance of machinery or equipment shall be performed only after the power is off, and the machinery or equipment blocked against hazardous motion. Machinery or equipment motion or...

  17. 30 CFR 56.14105 - Procedures during repairs or maintenance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Machinery and Equipment Safety Devices and Maintenance Requirements § 56.14105 Procedures during repairs or maintenance. Repairs or maintenance of machinery or equipment shall be performed only after the power is off, and the machinery or equipment blocked against hazardous motion. Machinery or equipment motion or...

  18. 30 CFR 57.14105 - Procedures during repairs or maintenance.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... MINES Machinery and Equipment Safety Devices and Maintenance Requirements § 57.14105 Procedures during repairs or maintenance. Repairs or maintenance on machinery or equipment shall be performed only after the power is off, and the machinery or equipment blocked against hazardous motion. Machinery or equipment...

  19. Engagement of groups in family medicine board maintenance of certification.

    PubMed

    Fisher, Dena M; Brenner, Christopher J; Cheren, Mark; Stange, Kurt C

    2013-01-01

    The American Board of Medical Specialties' Performance in Practice ("Part IV") portion of Maintenance of Certification (MOC) requirement provides an opportunity for practicing physicians to demonstrate quality improvement (QI) competence. However, specialty boards' certification of one physician at a time does not tap into the potential of collective effort. This article shares learning from a project to help family physicians work in groups to meet their Part IV MOC requirement. A year-long implementation and evaluation project was conducted. Initially, 348 members of a regional family physician organization were invited to participate. A second path was established through 3 health care systems and a county-wide learning collaborative. Participants were offered (1) a basic introduction to QI methods, (2) the option of an alternative Part IV MOC module using a patient experience survey to guide QI efforts, (3) practice-level improvement coaching, (4) support for collaboration and co-learning, and (5) provision of QI resources. More physicians participated through group (66) than individual (12) recruitment, for a total of 78 physicians in 20 practices. Participation occurred at 3 levels: individual, intrapractice, and interpractice. Within the 1-year time frame, intrapractice collaboration occurred most frequently. Interpractice and system-level collaboration has begun and continues to evolve. Physicians felt that they benefited from access to a practice coach and group process. Practice-level collaboration, access to a practice coach, flexibility in choosing and focusing improvement projects, tailored support, and involvement with professional affiliations can enhance the Part IV MOC process. Specialty boards are likely to discover productive opportunities from working with practices, professional organizations, and health care systems to support intra- and interpractice collaborative QI work that uses Part IV MOC requirements to motivate practice improvement.

  20. Drones in Automation - Secured Unmanned Aerial Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Morales Rodriguez, Marissa E.; Rooke, Sterling; Fuhr, Peter L.

    Factories, refineries, utilities (water/wastewater, electric) and related industrial sites are complex systems and structures with inspection and maintenance procedures required for optimal operation and regulatory compliance. As a specific example, consider just the bulk electric power system which is comprised of more than 200,000 miles of highvoltage transmission lines, thousands of generation plants and millions of digital controls. More than 1,800 entities own and operate portions of the grid system, with thousands more involved in the operation of distribution networks across North America. The interconnected and interdependent nature of the bulk power system requires a consistent and systematic application ofmore » risk mitigation across the entire grid system to be truly effective. Similar situations are found throughout automation where frequently an aging infrastructure is in place too. Consider, for example, the situation present in a refinery or chemical processing setting with the requirement for leak detection inspection of pipes, interconnects and systems stretching across the plant. The current practices and challenges relating just to this task - leak detection and repair (LDAR) – of detecting any fugitive emissions present and documenting all measurements thereby meeting air compliance regulations are typically “handled” by a small army of individuals with handheld or backpack-sized detectors who crawl through piping racks conducting measurements at each flange. Such work is performed in difficult conditions (temperature, humidity, physically challenging) with frequently a high level of employee turnover. Finaly, enter low cost sensors and mobile platforms – in other words unmanned aerial systems (UASs, or drones) with enhanced sensing capabilities.« less

  1. Drones in Automation - Secured Unmanned Aerial Systems

    DOE PAGES

    Morales Rodriguez, Marissa E.; Rooke, Sterling; Fuhr, Peter L.; ...

    2017-05-01

    Factories, refineries, utilities (water/wastewater, electric) and related industrial sites are complex systems and structures with inspection and maintenance procedures required for optimal operation and regulatory compliance. As a specific example, consider just the bulk electric power system which is comprised of more than 200,000 miles of highvoltage transmission lines, thousands of generation plants and millions of digital controls. More than 1,800 entities own and operate portions of the grid system, with thousands more involved in the operation of distribution networks across North America. The interconnected and interdependent nature of the bulk power system requires a consistent and systematic application ofmore » risk mitigation across the entire grid system to be truly effective. Similar situations are found throughout automation where frequently an aging infrastructure is in place too. Consider, for example, the situation present in a refinery or chemical processing setting with the requirement for leak detection inspection of pipes, interconnects and systems stretching across the plant. The current practices and challenges relating just to this task - leak detection and repair (LDAR) – of detecting any fugitive emissions present and documenting all measurements thereby meeting air compliance regulations are typically “handled” by a small army of individuals with handheld or backpack-sized detectors who crawl through piping racks conducting measurements at each flange. Such work is performed in difficult conditions (temperature, humidity, physically challenging) with frequently a high level of employee turnover. Finaly, enter low cost sensors and mobile platforms – in other words unmanned aerial systems (UASs, or drones) with enhanced sensing capabilities.« less

  2. Energy and protein requirements for maintenance of dairy goats during pregnancy and their efficiencies of use.

    PubMed

    Härter, C J; Lima, L D; Silva, H G O; Castagnino, D S; Rivera, A R; Resende, K T; Teixeira, I A M A

    2017-09-01

    It has been suggested that maintenance requirements are similar among animals of different physiological stages; however, important physiological changes occur in the maternal body during pregnancy. Therefore, the aim of this study was to determine the energy and protein requirements for the maintenance of pregnant dairy goats and to estimate their efficiency of energy and protein utilization for maintenance and pregnancy. We used 66 multiparous pregnant goats having 49.0 ± 1.59 kg initial BW (around the third or fourth parturition) arranged in a randomized block design with a 3 × 3 factorial scheme including slaughter at different days of pregnancy (DOP; 80, 110, and 140 d) and feed restriction (0, 20, and 40% feed restriction). The comparative slaughter technique was used to estimate energy and protein maintenance requirements. Goats slaughtered at 140 DOP were subjected to digestibility trials at around 80, 110, and 140 DOP to estimate diet metabolizability and N balance (NBAL). Metabolizability decreased with feed restriction and was 63.3 ± 2.16, 55.7 ± 2.35, and 58.2 ± 2.30% at 0, 20, and 40% of feed restriction, respectively ( < 0.01). There was no effect of DOP on NE or the requirements of ME for maintenance (ME), which were 197 and 315 kJ/kg empty body weight (EBW), respectively, and the efficiency of ME utilization for maintenance (k) was 0.63. Similarly, DOP did not affect thedaily net protein requirements for maintenance (NP) estimated using the comparative slaughter technique (1.38 ± 0.512 g/kg EBW; = 0.003) or the NP estimated using NBAL (2.49 ± 0.594 g/kg EBW; < 0.01). The MP requirement for maintenance (MP) estimated using the comparative slaughter technique was not affected by DOP and was 3.22 g MP/kg EBW ( < 0.01). The efficiency of MP utilization for maintenance (k) was 0.43. The efficiency of ME utilization for pregnancy (k) increased with the progress of pregnancy and was 0.058, 0.10, and 0.19 at 80, 110, and 140 DOP, respectively. Similarly, the efficiency of MP utilization for pregnancy (k) increased with DOP and was 0.12, 0.21, and 0.43 at 80, 110, and 140 DOP, respectively. There was no evidence that pregnancy affected NE, ME, NP, and MP or k and k, which were also unaffected by DOP. However, k and k increased with pregnancy progress as a response to the physiological changes that pregnant females are subjected to.

  3. Second Line of Defense: Electronic Maintenance Reports, Local Maintenance Provider User Guide, Rev. 3

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leigh, Richard J.

    2012-09-01

    The Electronic Maintenance Report forms allow Local Maintenance Providers (LMP) and other program staff to enter maintenance information into a simple and secure system. This document describes the features and information required to complete the Maintenance Report forms. It is expected that all Corrective Maintenance Reports from LMPs will be submitted electronically into the SLD Portal. As an exception (e.g., when access to the SLD Portal is unavailable), Maintenance Reports can be submitted via a secure Adobe PDF form available through the Sustainability Manager assigned to each country.

  4. Assessment of Surface Ship Maintenance Requirements

    DTIC Science & Technology

    2015-01-01

    specifically Operational Availability (Ao) and Expected Service Life ( ESL ). Second, it requested NDRI to develop a maintenance requirement concept for each...ship class that supports ESL but allows for some risk within the maintenance strategy. It also asked researchers to define the risks to Ao and ESL ...to minimize negative effects to Ao and ESL and maintain the largest, most capable fleet possible. Note that the tasking did not request a complete

  5. 10-MWe solar-thermal central-receiver pilot plant. Operating and maintenance manual

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1979-08-01

    Information required to perform the initial program loading and operation of the Heliostat Array Controller (HAC) is provided. Operating activities are described as required for heliostat control. All computer console command steps, from power up to power down are described. Detailed steps are provided to wake up the system and direct heliostat beams to standby, on target, standby to stow and power down. Maintenance requirements (preventive and corrective), reparability (reparable - non-reparable decisions), spares identification, spares storage location, replacement levels, replacement location and repair location are established. Individual system breakdown block diagrams are provided for each system/assembly/subassembly. Maintenance and repairmore » description sheets are provided for each maintenance significant item. The manual provides support of the following equipment: (a) helostat assembly; (b) heliostat control assembly; and (c) maintenance and installation equipment. The safety requirements for the operating and maintenance functions are established. These procedures will assist in eliminating or controlling the accident potentials caused by human error, environment, or component malfunctions or interactions that could result in major injury or fatality to operating or visiting personnel, or damage to subsystem components or support equipment. These procedures are for normal and test operating conditions and emergency situations, and apply to all Martin Marietta Corporation, governmental, operating and visitor personnel. (LEW)« less

  6. 27 CFR 19.723 - Maintenance and preservation of records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Maintenance and preservation of records. 19.723 Section 19.723 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX... General § 19.723 Maintenance and preservation of records. (a) Place of maintenance. Records required by...

  7. Differentiating Behavior Initiation and Maintenance: Theoretical Framework and Proof of Concept

    ERIC Educational Resources Information Center

    Voils, Corrine I.; Gierisch, Jennifer M.; Yancy, William S., Jr.; Sandelowski, Margarete; Smith, Rose; Bolton, Jamiyla; Strauss, Jennifer L.

    2014-01-01

    Although many interventions are effective for health behavior initiation, maintenance has proven elusive. Interventions targeting maintenance often extend the duration with which initiation content is delivered or the duration of follow-up without intervention. We posit that health behavior initiation and maintenance require separate psychological…

  8. A Guide to the Management and Maintenance of School Grounds.

    ERIC Educational Resources Information Center

    Wood, Joan; Littlewood, Michael

    This guidebook helps schools identify their maintenance requirements, choose the best organizational model of maintenance to ensure they receive a good quality service for their money, and help teachers and administrators achieve whole school awareness and commitment to school maintenance management. Sections address evaluating a school's…

  9. IMIS: Integrated Maintenance Information System. A maintenance information delivery concept

    NASA Technical Reports Server (NTRS)

    Vonholle, Joseph C.

    1987-01-01

    The Integrated Maintenance Information System (IMIS) will optimize the use of available manpower, enhance technical performance, improve training, and reduce the support equipment and documentation needed for deployment. It will serve as the technician's single, integrated source of all the technical information required to perform modern aircraft maintenance.

  10. 14 CFR 171.3 - Requests for IFR procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... manual that meets the requirements of § 171.11. (4) A statement of intention to meet the requirements of this subpart. (5) A showing that the facility has an acceptable level of operational reliability and an... required changes in the facility or the maintenance manual or maintenance organization. The owner must then...

  11. Energy and protein requirements for maintenance and growth of Boer crossbred kids.

    PubMed

    Fernandes, M H M R; Resende, K T; Tedeschi, L O; Fernandes, J S; Silva, H M; Carstens, G E; Berchielli, T T; Teixeira, I A M A; Akinaga, L

    2007-04-01

    Meat production by goats has become an important livestock enterprise in several parts of the world. Nonetheless, energy and protein requirements of meat goats have not been defined thoroughly. The objective of this study was to determine the energy and protein requirements for maintenance and growth of 34 (3/4) Boer x (1/4) Saanen crossbred, intact male kids (20.5 +/- 0.24 kg of initial BW). The baseline group was 7 randomly selected kids, averaging 21.2 +/- 0.36 kg of BW. An intermediate group consisted of 6 randomly selected kids, fed for ad libitum intake, that were slaughtered when they reached an average BW of 28.2 +/- 0.39 kg. The remaining kids (n = 21) were allocated randomly on d 0 to 3 levels of DMI (treatments were ad libitum or restricted to 70 or 40% of the ad libitum intake) within 7 slaughter groups. A slaughter group contained 1 kid from each treatment, and kids were slaughtered when the ad libitum treatment kid reached 35 kg of BW. Individual body components (head plus feet, hide, internal organs plus blood, and carcass) were weighed, ground, mixed, and subsampled for chemical analyses. Initial body composition was determined using equations developed from the composition of the baseline kids. The calculated daily maintenance requirement for NE was 77.3 +/- 1.05 kcal/kg(0.75) of empty BW (EBW) or 67.4 +/- 1.04 kcal/kg(0.75) of shrunk BW. The daily ME requirement for maintenance (118.1 kcal/kg(0.75) of EBW or 103.0 kcal/kg(0.75) of shrunk BW) was calculated by iteration, assuming that the heat produced was equal to the ME intake at maintenance. The partial efficiency of use of ME for NE below maintenance was 0.65. A value of 2.44 +/- 0.4 g of net protein/kg(0.75) of EBW for daily maintenance was determined. Net energy requirements for growth ranged from 2.55 to 3.0 Mcal/kg of EBW gain at 20 and 35 kg of BW, and net protein requirements for growth ranged from 178.8 to 185.2 g/kg of EBW gain. These results suggest that NE and net protein requirements for growing meat goats exceed the requirements previously published for dairy goats. Moreover, results from this study suggest that the N requirement for maintenance for growing goats is greater than the established recommendations.

  12. 23 CFR 630.1102 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... zone fatalities and injuries to workers and road users by establishing minimum requirements and..., installation and maintenance of temporary traffic control devices, and use of uniformed law enforcement officers during construction, utility, and maintenance operations, and by requiring contract pay items to...

  13. 49 CFR 214.507 - Required safety equipment for new on-track roadway maintenance machines.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... windshield wipers are incompatible with the windshield material; (5) A machine braking system capable of... Roadway Maintenance Machines and Hi-Rail Vehicles § 214.507 Required safety equipment for new on-track...

  14. Prescribed Grassland Burning Smoke Emission Measurements in the Northern Flint Hills Region

    EPA Science Inventory

    Historically, frequent wildfires were essential for the maintenance of native prairie fire adapted ecosystems. Today prescribed fires are used to control invasive woody species and potentially improve forage production in these same prairie ecosystems for the beef-cattle industry...

  15. Immunomodulator expression in trophoblasts from the feline immunodeficiency virus FIV infected cat

    USDA-ARS?s Scientific Manuscript database

    FIV infection frequently compromises pregnancy under experimental conditions and is accompanied by aberrant expression of some placental cytokines. Trophoblasts produce numerous immunomodulators that play a role in placental development and pregnancy maintenance. We hypothesized that FIV infection m...

  16. Applied approach slab settlement research, design/construction : final report.

    DOT National Transportation Integrated Search

    2013-08-01

    Approach embankment settlement is a pervasive problem in Oklahoma and many other states. The bump and/or abrupt slope change poses a danger to traffic and can cause increased dynamic loads on the bridge. Frequent and costly maintenance may be needed ...

  17. Failure to Manage Constant Change

    ERIC Educational Resources Information Center

    McDonald, Ann

    2010-01-01

    This study examines patterns of system failure (communication, typographic, material, economic, maintenance) and the resulting workarounds in signs that are intended to communicate frequently changing information in the built environment. The observed failures and workarounds in the communication of ephemeral data and the accompanying narratives…

  18. Extended-release mesalamine granules for ulcerative colitis.

    PubMed

    Love, Bryan L; Miller, April D

    2012-11-01

    To evaluate the efficacy and safety of extended-release mesalamine granules in the maintenance of remission in ulcerative colitis (UC). Literature was obtained through searches of MEDLINE (1990-June 2012) using the terms mesalamine granules, ulcerative colitis, Apriso, and Salofalk. Bibliographies from retrieved articles were searched for additional citations. All English-language articles reporting on use of extended-release mesalamine granules in humans identified through the search were evaluated and included. The preferred initial treatment for induction and maintenance of remission in mild to moderate UC is agents from the 5-aminosalicylate class (balsalazide, mesalamine, olsalazine, sulfasalazine). Mesalamine granules are available as an encapsulated product in the US and as a nonencapsulated formulation in Europe. Data evaluating encapsulated mesalamine granules for induction of remission are lacking; however, the European mesalamine granule formulation has been evaluated for induction of remission. Patients receiving mesalamine granules for induction achieved clinical and endoscopic remission more frequently than those receiving placebo. Two pivotal, randomized, double-blind, placebo-controlled, multicenter studies have evaluated encapsulated mesalamine granules for maintenance in 562 adults in remission from UC. In both studies, the proportion of patients who remained relapse-free at 6 months was higher for those receiving encapsulated mesalamine granules than placebo. Mesalamine granules are well tolerated, with headache, nausea, and upper respiratory infections being the most frequently reported adverse effects. Current evidence supports the use of extended-release mesalamine granules for maintenance of remission in mild to moderate UC. Further studies are necessary to examine the ideal dose and regimen of encapsulated mesalamine granules for induction of remission in UC.

  19. 40 CFR 52.1174 - Control strategy: Ozone.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... oxides of nitrogen requirements for conformity and new source review. Theses are required by sections 176... architectural, industrial, and maintenance coatings rule; auto body refinisher self-certification audit program... architectural, industrial, and maintenance coatings rule; auto body refinisher self-certification audit program...

  20. 40 CFR 52.1174 - Control strategy: Ozone.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... oxides of nitrogen requirements for conformity and new source review. Theses are required by sections 176... architectural, industrial, and maintenance coatings rule; auto body refinisher self-certification audit program... architectural, industrial, and maintenance coatings rule; auto body refinisher self-certification audit program...

  1. 40 CFR 52.1174 - Control strategy: Ozone.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... oxides of nitrogen requirements for conformity and new source review. Theses are required by sections 176... architectural, industrial, and maintenance coatings rule; auto body refinisher self-certification audit program... architectural, industrial, and maintenance coatings rule; auto body refinisher self-certification audit program...

  2. 40 CFR 52.1174 - Control strategy: Ozone.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... oxides of nitrogen requirements for conformity and new source review. Theses are required by sections 176... architectural, industrial, and maintenance coatings rule; auto body refinisher self-certification audit program... architectural, industrial, and maintenance coatings rule; auto body refinisher self-certification audit program...

  3. 40 CFR 52.1174 - Control strategy: Ozone.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... oxides of nitrogen requirements for conformity and new source review. Theses are required by sections 176... architectural, industrial, and maintenance coatings rule; auto body refinisher self-certification audit program... architectural, industrial, and maintenance coatings rule; auto body refinisher self-certification audit program...

  4. 7 CFR 1730.26 - Certification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ELECTRIC SYSTEM OPERATIONS AND MAINTENANCE Operations and Maintenance Requirements § 1730.26 Certification. (a) Engineer's certification. Where provided for in the borrower's loan documents, RUS may require the borrower to provide an “Engineer's Certification” as to the condition of the borrower's system...

  5. 7 CFR 1730.26 - Certification.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ELECTRIC SYSTEM OPERATIONS AND MAINTENANCE Operations and Maintenance Requirements § 1730.26 Certification. (a) Engineer's certification. Where provided for in the borrower's loan documents, RUS may require the borrower to provide an “Engineer's Certification” as to the condition of the borrower's system...

  6. 7 CFR 1730.26 - Certification.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ELECTRIC SYSTEM OPERATIONS AND MAINTENANCE Operations and Maintenance Requirements § 1730.26 Certification. (a) Engineer's certification. Where provided for in the borrower's loan documents, RUS may require the borrower to provide an “Engineer's Certification” as to the condition of the borrower's system...

  7. 7 CFR 1730.26 - Certification.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ELECTRIC SYSTEM OPERATIONS AND MAINTENANCE Operations and Maintenance Requirements § 1730.26 Certification. (a) Engineer's certification. Where provided for in the borrower's loan documents, RUS may require the borrower to provide an “Engineer's Certification” as to the condition of the borrower's system...

  8. 7 CFR 1730.26 - Certification.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ELECTRIC SYSTEM OPERATIONS AND MAINTENANCE Operations and Maintenance Requirements § 1730.26 Certification. (a) Engineer's certification. Where provided for in the borrower's loan documents, RUS may require the borrower to provide an “Engineer's Certification” as to the condition of the borrower's system...

  9. 40 CFR 63.1547 - Monitoring requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... standard operating procedures manual that describes in detail the procedures for inspection, maintenance...) The standard operating procedures manual for baghouses required by paragraph (a) of this section shall... specified in the standard operating procedures manual for inspections and routine maintenance shall, at a...

  10. 40 CFR 63.1547 - Monitoring requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... standard operating procedures manual that describes in detail the procedures for inspection, maintenance...) The standard operating procedures manual for baghouses required by paragraph (a) of this section shall... specified in the standard operating procedures manual for inspections and routine maintenance shall, at a...

  11. 40 CFR 63.1347 - Operation and maintenance plan requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants From the Portland Cement Manufacturing Industry Emission Standards and Operating Limits § 63.1347 Operation and maintenance plan requirements. (a...

  12. 40 CFR 63.1347 - Operation and maintenance plan requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants From the Portland Cement Manufacturing Industry Emission Standards and Operating Limits § 63.1347 Operation and maintenance plan requirements. (a...

  13. 40 CFR 63.1108 - Compliance with standards and operation and maintenance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... operation and maintenance requirements. 63.1108 Section 63.1108 Protection of Environment ENVIRONMENTAL... Source Categories: Generic Maximum Achievable Control Technology Standards § 63.1108 Compliance with..., air pollution control technologies, recovery technologies, work practices, pollution prevention...

  14. 14 CFR 171.31 - Maintenance and operations requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the Federal Communications Commission's licensing requirements and show that he has the special knowledge and skills needed to maintain the facility including proficiency in maintenance procedures and the... of servicing. (8) Air-ground communications, if provided, expressly written or incorporating...

  15. 14 CFR 171.31 - Maintenance and operations requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the Federal Communications Commission's licensing requirements and show that he has the special knowledge and skills needed to maintain the facility including proficiency in maintenance procedures and the... of servicing. (8) Air-ground communications, if provided, expressly written or incorporating...

  16. 14 CFR 171.31 - Maintenance and operations requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the Federal Communications Commission's licensing requirements and show that he has the special knowledge and skills needed to maintain the facility including proficiency in maintenance procedures and the... of servicing. (8) Air-ground communications, if provided, expressly written or incorporating...

  17. 14 CFR 171.31 - Maintenance and operations requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the Federal Communications Commission's licensing requirements and show that he has the special knowledge and skills needed to maintain the facility including proficiency in maintenance procedures and the... of servicing. (8) Air-ground communications, if provided, expressly written or incorporating...

  18. 14 CFR 171.51 - Maintenance and operations requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... meet at least the Federal Communications Commission's licensing requirements and show that he has the special knowledge and skills needed to maintain the facility including proficiency in maintenance... servicing. (8) Air-ground communications, if provided, expressly written or incorporating appropriate...

  19. 14 CFR 171.51 - Maintenance and operations requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... meet at least the Federal Communications Commission's licensing requirements and show that he has the special knowledge and skills needed to maintain the facility including proficiency in maintenance... servicing. (8) Air-ground communications, if provided, expressly written or incorporating appropriate...

  20. 14 CFR 171.31 - Maintenance and operations requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the Federal Communications Commission's licensing requirements and show that he has the special knowledge and skills needed to maintain the facility including proficiency in maintenance procedures and the... of servicing. (8) Air-ground communications, if provided, expressly written or incorporating...

  1. 75 FR 37457 - Maintenance Wage Rate Wage Recommendation and Maintenance Wage Survey; Report of Additional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-29

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5376-N-54] Maintenance Wage Rate Wage Recommendation and Maintenance Wage Survey; Report of Additional Classification and Wage Rate AGENCY: Office of... requirement described below has been submitted to the Office of Management and Budget (OMB) for review, as...

  2. 75 FR 4099 - Maintenance Wage Rate Wage Recommendation and Maintenance Wage Survey; Report of Additional...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-26

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5376-N-06] Maintenance Wage Rate Wage Recommendation and Maintenance Wage Survey; Report of Additional Classification and Wage Rate AGENCY: Office of... requirement described below has been submitted to the Office of Management and Budget (OMB) for review, as...

  3. 40 CFR 1039.125 - What maintenance instructions must I give to buyers?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... disqualify those engines from in-use testing or deny a warranty claim. Do not take these maintenance steps... specified special maintenance steps to address engine operation that is not atypical, or that the... ENGINES Emission Standards and Related Requirements § 1039.125 What maintenance instructions must I give...

  4. The ABPN Maintenance of Certification Program for psychiatrists: past history, current status, and future directions.

    PubMed

    Faulkner, Larry R; Tivnan, Patricia W; Winstead, Daniel K; Reus, Victor I; Andrade, Naleen N; Brooks, Beth Ann; Colenda, Christopher C; Mrazek, David A; Reifler, Burton V; Schneidman, Barbara

    2008-01-01

    To describe the American Board of Psychiatry and Neurology (ABPN) Maintenance of Certification Program, its underlying rationale, how it will be implemented now, and what it might look like in the future. The authors describe the philosophical foundation, specific components, and the implementation timeline of the ABPN Maintenance of Certification Program; the development of specific products that might be used by ABPN diplomates to meet its requirements; and several unanswered questions about its current status and future development. The ABPN Maintenance of Certification Program consists of specific requirements pertaining to professional standing, self-assessment and lifelong learning, performance in practice, and cognitive expertise that will be implemented incrementally over the next decade. The ABPN Maintenance of Certification Program has been implemented in a manner that is as consistent as possible with its underlying philosophical beliefs as well as the current and expected public and political concerns, diplomate needs, and the requirements of organizations responsible for licensure, credentialing, privileging, accreditation, professional development, and physician reimbursement.

  5. The activity of the inosine triphosphate pyrophosphatase affects toxicity of 6-mercaptopurine during maintenance therapy for acute lymphoblastic leukemia in Japanese children.

    PubMed

    Tanaka, Yoichi; Manabe, Atsushi; Nakadate, Hisaya; Kondoh, Kensuke; Nakamura, Kozue; Koh, Katsuyoshi; Utano, Tomoyuki; Kikuchi, Akira; Komiyama, Takako

    2012-05-01

    The association between inosine triphosphate pyrophosphatase (ITPA) activity and toxicity of 6-mercaptopurine (6-MP) was retrospectively evaluated in 65 Japanese children with acute lymphoblastic leukemia (ALL). Patients with an ITPA activity of less than 126 μmol/h/gHb presented with hepatotoxicity more frequently than those with higher ITPA activity (p<0.01). The average 6-MP dose during maintenance therapy administered to two patients with the ITPA deficiency was lower than that given to the other patients. Measuring ITPA activity is important for ensuring the safety of maintenance therapy for Asians with ALL because thiopurine S-methyl transferase mutations are rare in the Asian population. Copyright © 2011 Elsevier Ltd. All rights reserved.

  6. Vehicle Maintenance Manpower Requirements for U.S. Army Installation Directorates of Engineering and Housing Based on Air Force, Navy, and Army Reserves’ Staffing Techniques.

    DTIC Science & Technology

    1986-07-01

    Reserves staffing. A comparison with the Navy technique, which requires estimates of mileage and operating hours, was not possible since these data were...Directorate of Engineering and Housing (DEH) vehicle maintenance activities. To make comparisons, manpower requirements data totaling two megabytes of

  7. 9 CFR 71.4 - Maintenance of certain facilities and premises in a sanitary condition required; cleaning and...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Maintenance of certain facilities and premises in a sanitary condition required; cleaning and disinfection, when required; animals classed as âexposed.â 71.4 Section 71.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  8. 9 CFR 71.4 - Maintenance of certain facilities and premises in a sanitary condition required; cleaning and...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Maintenance of certain facilities and premises in a sanitary condition required; cleaning and disinfection, when required; animals classed as âexposed.â 71.4 Section 71.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  9. 9 CFR 71.4 - Maintenance of certain facilities and premises in a sanitary condition required; cleaning and...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Maintenance of certain facilities and premises in a sanitary condition required; cleaning and disinfection, when required; animals classed as âexposed.â 71.4 Section 71.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  10. 9 CFR 71.4 - Maintenance of certain facilities and premises in a sanitary condition required; cleaning and...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Maintenance of certain facilities and premises in a sanitary condition required; cleaning and disinfection, when required; animals classed as âexposed.â 71.4 Section 71.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  11. 9 CFR 71.4 - Maintenance of certain facilities and premises in a sanitary condition required; cleaning and...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Maintenance of certain facilities and premises in a sanitary condition required; cleaning and disinfection, when required; animals classed as âexposed.â 71.4 Section 71.4 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...

  12. Impact of System Expansion on Maintenance Resources.

    DOT National Transportation Integrated Search

    2012-09-01

    The basic focus of this research project is developing a marginal maintenance cost mechanism for new construction projects. This mechanism will identify the total expected short-term and long-term maintenance burden required for each construction pro...

  13. Framework and implementation of a continuous network-wide health monitoring system for roadways

    NASA Astrophysics Data System (ADS)

    Wang, Ming; Birken, Ralf; Shahini Shamsabadi, Salar

    2014-03-01

    According to the 2013 ASCE report card America's infrastructure scores only a D+. There are more than four million miles of roads (grade D) in the U.S. requiring a broad range of maintenance activities. The nation faces a monumental problem of infrastructure management in the scheduling and implementation of maintenance and repair operations, and in the prioritization of expenditures within budgetary constraints. The efficient and effective performance of these operations however is crucial to ensuring roadway safety, preventing catastrophic failures, and promoting economic growth. There is a critical need for technology that can cost-effectively monitor the condition of a network-wide road system and provide accurate, up-to-date information for maintenance activity prioritization. The Versatile Onboard Traffic Embedded Roaming Sensors (VOTERS) project provides a framework and the sensing capability to complement periodical localized inspections to continuous network-wide health monitoring. Research focused on the development of a cost-effective, lightweight package of multi-modal sensor systems compatible with this framework. An innovative software infrastructure is created that collects, processes, and evaluates these large time-lapse multi-modal data streams. A GIS-based control center manages multiple inspection vehicles and the data for further analysis, visualization, and decision making. VOTERS' technology can monitor road conditions at both the surface and sub-surface levels while the vehicle is navigating through daily traffic going about its normal business, thereby allowing for network-wide frequent assessment of roadways. This deterioration process monitoring at unprecedented time and spatial scales provides unique experimental data that can be used to improve life-cycle cost analysis models.

  14. 14 CFR 171.273 - Maintenance and operations requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... guides stating the frequency of servicing. (8) Air-ground communications, if provided, expressly written... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Maintenance and operations requirements. 171.273 Section 171.273 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...

  15. 14 CFR 171.273 - Maintenance and operations requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... guides stating the frequency of servicing. (8) Air-ground communications, if provided, expressly written... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Maintenance and operations requirements. 171.273 Section 171.273 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...

  16. 14 CFR 171.273 - Maintenance and operations requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... guides stating the frequency of servicing. (8) Air-ground communications, if provided, expressly written... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Maintenance and operations requirements. 171.273 Section 171.273 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...

  17. 14 CFR 171.273 - Maintenance and operations requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... guides stating the frequency of servicing. (8) Air-ground communications, if provided, expressly written... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Maintenance and operations requirements. 171.273 Section 171.273 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...

  18. 14 CFR 171.273 - Maintenance and operations requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... guides stating the frequency of servicing. (8) Air-ground communications, if provided, expressly written... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Maintenance and operations requirements. 171.273 Section 171.273 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...

  19. 41 CFR 101-30.503 - Maintenance actions required.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Maintenance actions required. 101-30.503 Section 101-30.503 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 30-FEDERAL...

  20. Garnering Support

    ERIC Educational Resources Information Center

    Kincaid, Douglas W.; Dillinger, Eric T.; Clayton, Michael

    2006-01-01

    Maintenance and operations (M&O) requirements dominate the life-cycle cost of a school facility. Historically, facility managers have struggled to secure funding to meet these requirements. Many deferred-maintenance issues result directly from M&O underfunding. However, new approaches and technologies now enable facility managers to use…

  1. 40 CFR 61.14 - Monitoring requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... determination of whether acceptable operating and maintenance procedures are being used will be based on information which may include, but not be limited to, review of operating and maintenance procedures...) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS General Provisions § 61.14 Monitoring requirements...

  2. 40 CFR 61.14 - Monitoring requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... determination of whether acceptable operating and maintenance procedures are being used will be based on information which may include, but not be limited to, review of operating and maintenance procedures...) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS General Provisions § 61.14 Monitoring requirements...

  3. 40 CFR 61.14 - Monitoring requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... determination of whether acceptable operating and maintenance procedures are being used will be based on information which may include, but not be limited to, review of operating and maintenance procedures...) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS General Provisions § 61.14 Monitoring requirements...

  4. 40 CFR 63.1347 - Operation and maintenance plan requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES National Emission Standards for Hazardous Air Pollutants From the Portland Cement Manufacturing Industry Emission Standards and Operating Limits § 63.1347 Operation and maintenance plan requirements. (a) You must...

  5. 40 CFR 61.14 - Monitoring requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... determination of whether acceptable operating and maintenance procedures are being used will be based on information which may include, but not be limited to, review of operating and maintenance procedures...) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS General Provisions § 61.14 Monitoring requirements...

  6. 40 CFR 63.1347 - Operation and maintenance plan requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES National Emission Standards for Hazardous Air Pollutants From the Portland Cement Manufacturing Industry Emission Standards and Operating Limits § 63.1347 Operation and maintenance plan requirements. (a) You must...

  7. 40 CFR 61.14 - Monitoring requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... determination of whether acceptable operating and maintenance procedures are being used will be based on information which may include, but not be limited to, review of operating and maintenance procedures...) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS General Provisions § 61.14 Monitoring requirements...

  8. 49 CFR 236.1043 - Task analysis and basic requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Positive Train Control Systems § 236.1043 Task analysis and basic requirements. (a) Training structure and... installation, maintenance, repair, modification, inspection, testing, and operating tasks that must be...

  9. 49 CFR 236.1043 - Task analysis and basic requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Positive Train Control Systems § 236.1043 Task analysis and basic requirements. (a) Training structure and... installation, maintenance, repair, modification, inspection, testing, and operating tasks that must be...

  10. 49 CFR 236.1043 - Task analysis and basic requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Positive Train Control Systems § 236.1043 Task analysis and basic requirements. (a) Training structure and... installation, maintenance, repair, modification, inspection, testing, and operating tasks that must be...

  11. 49 CFR 236.1043 - Task analysis and basic requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Positive Train Control Systems § 236.1043 Task analysis and basic requirements. (a) Training structure and... installation, maintenance, repair, modification, inspection, testing, and operating tasks that must be...

  12. 49 CFR 236.1043 - Task analysis and basic requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Positive Train Control Systems § 236.1043 Task analysis and basic requirements. (a) Training structure and... installation, maintenance, repair, modification, inspection, testing, and operating tasks that must be...

  13. 14 CFR 19-2 - Maintenance of data.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Operating Statistics Classifications Sec. 19-2 Maintenance of data. (a) Each air carrier required to file... in accordance with the uniform classifications prescribed. Codes are prescribed for each operating... flight numbers. The second grouping requires that the enplanement/deplanement information be broken out...

  14. 42 CFR 124.510 - Record maintenance requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Record maintenance requirements. 124.510 Section 124.510 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH RESOURCES DEVELOPMENT MEDICAL FACILITY CONSTRUCTION AND MODERNIZATION Reasonable Volume of Uncompensated Services to...

  15. 42 CFR 124.510 - Record maintenance requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Record maintenance requirements. 124.510 Section 124.510 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH RESOURCES DEVELOPMENT MEDICAL FACILITY CONSTRUCTION AND MODERNIZATION Reasonable Volume of Uncompensated Services to...

  16. 42 CFR 124.510 - Record maintenance requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Record maintenance requirements. 124.510 Section 124.510 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH RESOURCES DEVELOPMENT MEDICAL FACILITY CONSTRUCTION AND MODERNIZATION Reasonable Volume of Uncompensated Services to...

  17. 76 FR 39259 - Manual Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-06

    ... established new requirements for the certification, operation, and maintenance of light-sport aircraft under... entitled ``Certification of Aircraft and Airmen for the Operation of Light-Sport Aircraft,'' in the Federal..., operation, and maintenance of light-sport aircraft. That final rule also redesignated the concluding text of...

  18. Defense Logistics: Space-Available Travel Challenges May Be Exacerbated If Eligibility Expands

    DTIC Science & Technology

    2012-09-10

    space-available travelers’ use of terminal facilities results in additional maintenance costs for waiting areas, restrooms, and vending machines ...additional required maintenance. For example, additional travelers’ use of waiting areas, restrooms, and vending machines in the terminals could require

  19. [Hospital maintenance: management, risks, and responsibilities].

    PubMed

    Rabino, F

    2002-01-01

    Principal activities of maintenance carried out in hospital, staff required, various type of organization (inside team or global service), management aspects are described. Subjects responsible of maintenance are characterized and the relationships between Service of Maintenance and Service of Prevention and Protection in hospital are specified. Responsibility aspects concerning safety of maintenance workers and main risks which are exposed are defined. The importance of disponibility of a good maintenance handbook and of projects and programs of practice for new hospitals are emphasized.

  20. Multi-objective group scheduling optimization integrated with preventive maintenance

    NASA Astrophysics Data System (ADS)

    Liao, Wenzhu; Zhang, Xiufang; Jiang, Min

    2017-11-01

    This article proposes a single-machine-based integration model to meet the requirements of production scheduling and preventive maintenance in group production. To describe the production for identical/similar and different jobs, this integrated model considers the learning and forgetting effects. Based on machine degradation, the deterioration effect is also considered. Moreover, perfect maintenance and minimal repair are adopted in this integrated model. The multi-objective of minimizing total completion time and maintenance cost is taken to meet the dual requirements of delivery date and cost. Finally, a genetic algorithm is developed to solve this optimization model, and the computation results demonstrate that this integrated model is effective and reliable.

  1. Revision of certification standards for aviation maintenance personnel

    NASA Technical Reports Server (NTRS)

    Vipond, Leslie K.

    1992-01-01

    Part 65, Subparts D and E, of the Federal Aviation Regulations (FAR) identify the certification requirements for aviation mechanics and aviation repairmen. The training, experience, privileges, ratings, recordkeeping, and currency requirements for aviation maintenance personnel are also addressed by those parts of the FAR. The recent emergence of the aging fleet problem and the introduction of new technologies, aircraft, engines, and aeronautical products has caused certain portions of these rules to become obsolete. Further, international political arrangements, such as bilateral airworthiness and maintenance agreements, International Civil Aviation Organization (ICAO) standards, certain international agreements for maintenance personnel training, and mechanic certificate reciprocity, have all impacted on the current regulatory policy.

  2. Maintenance and Logistics Support for the International Monitoring System Network of the CTBTO

    NASA Astrophysics Data System (ADS)

    Haslinger, F.; Brely, N.; Akrawy, M.

    2007-05-01

    The global network of the International Monitoring System (IMS) of the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO), once completed, will consist of 321 monitoring facilities of four different technologies: hydroacoustic, seismic, infrasonic, and radionuclide. As of today, about 65% of the installations are completed and contribute data to the products issued by the International Data Centre (IDC) of the CTBTO. In order to accomplish the task to reliably collect evidence for any potential nuclear test explosion anywhere on the planet, all stations are required to perform to very high data availability requirements (at least 98% data availability over a 12-month period). To enable reaching this requirement, a three-layer concept has been developed to allow efficient support of the IMS stations: Operations, Maintenance and Logistics, and Engineering. Within this concept Maintenance and Logistics provide second level support of the stations, whereby problems arising at the station are assigned through the IMS ticket system to Maintenance if they cannot be resolved on the Operations level. Maintenance will then activate the required resources to appropriately address and ultimately resolve the problem. These resources may be equipment support contracts, other third party contracts, or the dispatch of a maintenance team. Engineering Support will be activated if the problem requires redesign of the station or after catastrophic failures when a total rebuild of a station may be necessary. In this model, Logistics Support is responsible for parts replenishment and support contract management. Logistics Support also collects and analyzes relevant failure mode and effect information, develops supportability models, and has the responsibility for document management, obsolescence, risk & quality, and configuration management, which are key elements for efficient station support. Maintenance Support in addition is responsible for maintenance strategies, for planning and oversight of the execution of preventive maintenance programs by the Station Operators, and for review of operational troubleshooting procedures used in first level support. Particular challenges for the efficient and successful Maintenance and Logistics Support of the IMS network lie in the specific political boundary conditions regulating its implementation, in the fact that all IMS facilities and their equipment are owned by the respective host countries, and in finding the appropriate balance between outsourcing services and retaining essential in-house expertise.

  3. 50 CFR 80.17 - Maintenance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE REQUIREMENTS, PITTMAN-ROBERTSON WILDLIFE RESTORATION AND DINGELL-JOHNSON SPORT FISH RESTORATION ACTS § 80.17 Maintenance. The State is responsible for maintenance of all capital improvements acquired or constructed with Wildlife and Sport Fish...

  4. Differences in health care utilization between parents who perceive their child as vulnerable versus overprotective parents.

    PubMed

    Thomasgard, M; Metz, W P

    1996-06-01

    While a parental perception of child vulnerability to illness/injury is often used interchangeably with parental overprotection, research suggests that they are independent constructs. We hypothesized more frequent pediatric nonwell-child visits for perceived child vulnerability, but not for parental overprotection. The parents of 300 children, ages 2-5 years, enrolled in a health maintenance organization, were sampled. For children without medical conditions, there were no differences in nonwell-child care visits between the high perceived vulnerability and high parental protection groups (Wilcoxon Rank Sum Test, WRST, P = .31). As expected, high parental protection was not significantly associated with increased nonwell-child care visits compared with the low parental protection group (WRST, P = .14). These findings suggest that markers other than health care utilization are required to identify these forms of parent-child relationship disorders.

  5. Evaluation of hypophosphatemia: lessons from patients with genetic disorders

    PubMed Central

    Bacchetta, Justine; Salusky, Isidro B

    2014-01-01

    Phosphate is a key element for several physiological pathways, such as skeletal development, bone mineralization, membrane composition, nucleotide structure, maintenance of plasma pH, and cellular signaling. The kidneys have a key role in phosphate homeostasis with three hormones playing important roles in renal phosphate handling (i.e., parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), and 1-25 dihydroxy-vitamin D). Independently of the genetic diseases affecting the FGF23 pathway (such as hypophosphatemic rickets), hypophosphatemia is a frequent condition in daily practice, and untreated severe hypophosphatemia can induce hemolysis, rhabdomyolysis, respiratory failure, cardiac dysfunction and neurological impairment, thus requiring a rapid correction to avoid severe complications. The aims of this case report are to summarize the etiologies and the biological evaluation of hypophosphatemia in adults, and to provide an overview of our current understanding of phosphate metabolism. PMID:22075221

  6. Analysis of loss of time value during road maintenance project

    NASA Astrophysics Data System (ADS)

    Sudarsana, Dewa Ketut; Sanjaya, Putu Ari

    2017-06-01

    Lane closure is frequently performed in the execution of the road maintenance project. It has a negative impact on road users such as the loss of vehicle operating costs and the loss of time value. Nevertheless, analysis on loss of time value in Indonesia has not been carried out. The parameter of time value for the road users was the minimum wage city/region approach. Vehicle speed of pre-construction was obtained by observation, while the speed during the road maintenance project was predicted by the speed of the pre-construction by multiplying it with the speed adjustment factor. In the case of execution of the National road maintenance project in the two-lane two-way urban and interurban road types in the fiscal year of 2015 in Bali province, the loss of time value was at the average of IDR 12,789,000/day/link road. The relationship of traffic volume and loss of time value of the road users was obtained by a logarithm model.

  7. Maintenance of Mechanical Services. Maintenance and Renewal in Educational Buildings. Building Bulletin 70.

    ERIC Educational Resources Information Center

    Haworth-Roberts, A., Ed.

    School building maintenance must find an appropriate balance between planned and reactive work in order to conserve costs. This document provides ways in which authorities can assess their maintenance requirements and make better use of the resources available. It considers how to deal with problems which have their roots in historical design…

  8. 40 CFR 61.12 - Compliance with standards and maintenance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Provisions § 61.12 Compliance with standards and maintenance requirements. (a) Compliance with numerical... otherwise specified in an individual subpart. (b) Compliance with design, equipment, work practice or... pollution control, in a manner consistent with good air pollution control practice for minimizing emissions...

  9. 14 CFR 60.19 - Inspection, continuing qualification evaluation, and maintenance requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Inspection, continuing qualification evaluation, and maintenance requirements. 60.19 Section 60.19 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND...

  10. 14 CFR 60.19 - Inspection, continuing qualification evaluation, and maintenance requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Inspection, continuing qualification evaluation, and maintenance requirements. 60.19 Section 60.19 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND...

  11. 14 CFR 60.19 - Inspection, continuing qualification evaluation, and maintenance requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Inspection, continuing qualification evaluation, and maintenance requirements. 60.19 Section 60.19 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND...

  12. 14 CFR 60.19 - Inspection, continuing qualification evaluation, and maintenance requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Inspection, continuing qualification evaluation, and maintenance requirements. 60.19 Section 60.19 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND...

  13. 14 CFR 60.19 - Inspection, continuing qualification evaluation, and maintenance requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Inspection, continuing qualification evaluation, and maintenance requirements. 60.19 Section 60.19 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND...

  14. 14 CFR 119.49 - Contents of operations specifications.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... markings, and serial number of each aircraft that is subject to an airworthiness maintenance program..., and emergency equipment of aircraft that are subject to an airworthiness maintenance program required... Transportation, if required. (4) Type of aircraft, registration markings, and serial numbers of each aircraft...

  15. 14 CFR 119.49 - Contents of operations specifications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... markings, and serial number of each aircraft that is subject to an airworthiness maintenance program..., and emergency equipment of aircraft that are subject to an airworthiness maintenance program required... Transportation, if required. (4) Type of aircraft, registration markings, and serial numbers of each aircraft...

  16. 14 CFR 119.49 - Contents of operations specifications.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... markings, and serial number of each aircraft that is subject to an airworthiness maintenance program..., and emergency equipment of aircraft that are subject to an airworthiness maintenance program required... Transportation, if required. (4) Type of aircraft, registration markings, and serial numbers of each aircraft...

  17. 14 CFR 119.49 - Contents of operations specifications.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... markings, and serial number of each aircraft that is subject to an airworthiness maintenance program..., and emergency equipment of aircraft that are subject to an airworthiness maintenance program required... Transportation, if required. (4) Type of aircraft, registration markings, and serial numbers of each aircraft...

  18. 76 FR 64788 - Airworthiness Directives; BAE SYSTEMS (Operations) Limited Model 4101 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-19

    ... ``Certification Maintenance Requirements'', and, --05-10-30 ``Critical Design Configuration Control Limitations... Limitations''; 05-10-20, ``Certification Maintenance Requirements''; and 05-10-30, ``Critical Design... BAE Systems (Operations) Limited Jetstream Series 4100 AMM, Revision 35, dated February 15, 2011. We...

  19. 45 CFR 1356.60 - Fiscal requirements (title IV-E).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... expenditures for: (i) Foster care maintenance payments as defined in section 475(4) of the Act, made in... SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON CHILDREN, YOUTH AND FAMILIES, FOSTER CARE MAINTENANCE PAYMENTS, ADOPTION ASSISTANCE, AND CHILD AND FAMILY SERVICES REQUIREMENTS...

  20. 45 CFR 1356.60 - Fiscal requirements (title IV-E).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... expenditures for: (i) Foster care maintenance payments as defined in section 475(4) of the Act, made in... SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON CHILDREN, YOUTH AND FAMILIES, FOSTER CARE MAINTENANCE PAYMENTS, ADOPTION ASSISTANCE, AND CHILD AND FAMILY SERVICES REQUIREMENTS...

  1. Floors: Care and Maintenance.

    ERIC Educational Resources Information Center

    Post Office Dept., Washington, DC.

    Guidelines, methods and policies regarding the care and maintenance of post office building floors are overviewed in this handbook. Procedures outlined are concerned with maintaining a required level of appearance without wasting manpower. Flooring types and characteristics and the particular cleaning requirements of each type are given along with…

  2. 40 CFR 141.806 - Reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... development of the coliform sampling plan, the operations and maintenance plan, and the disinfection and... operations and maintenance plan required by § 141.804 and report the frequency for routine disinfection and... frequency for routine disinfection and flushing within the first calendar quarter of initial operation of...

  3. 40 CFR 141.806 - Reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... development of the coliform sampling plan, the operations and maintenance plan, and the disinfection and... operations and maintenance plan required by § 141.804 and report the frequency for routine disinfection and... frequency for routine disinfection and flushing within the first calendar quarter of initial operation of...

  4. An alternative cost-effective image processing based sensor for continuous turbidity monitoring

    NASA Astrophysics Data System (ADS)

    Chai, Matthew Min Enn; Ng, Sing Muk; Chua, Hong Siang

    2017-03-01

    Turbidity is the degree to which the optical clarity of water is reduced by impurities in the water. High turbidity values in rivers and lakes promote the growth of pathogen, reduce dissolved oxygen levels and reduce light penetration. The conventional ways of on-site turbidity measurements involve the use of optical sensors similar to those used in commercial turbidimeters. However, these instruments require frequent maintenance due to biological fouling on the sensors. Thus, image processing was proposed as an alternative technique for continuous turbidity measurement to reduce frequency of maintenance. The camera was kept out of water to avoid biofouling while other parts of the system submerged in water can be coated with anti-fouling surface. The setup developed consisting of a webcam, a light source, a microprocessor and a motor used to control the depth of a reference object. The image processing algorithm quantifies the relationship between the number of circles detected on the reference object and the depth of the reference object. By relating the quantified data to turbidity, the setup was able to detect turbidity levels from 20 NTU to 380 NTU with measurement error of 15.7 percent. The repeatability and sensitivity of the turbidity measurement was found to be satisfactory.

  5. PipelineDog: a simple and flexible graphic pipeline construction and maintenance tool.

    PubMed

    Zhou, Anbo; Zhang, Yeting; Sun, Yazhou; Xing, Jinchuan

    2018-05-01

    Analysis pipelines are an essential part of bioinformatics research, and ad hoc pipelines are frequently created by researchers for prototyping and proof-of-concept purposes. However, most existing pipeline management system or workflow engines are too complex for rapid prototyping or learning the pipeline concept. A lightweight, user-friendly and flexible solution is thus desirable. In this study, we developed a new pipeline construction and maintenance tool, PipelineDog. This is a web-based integrated development environment with a modern web graphical user interface. It offers cross-platform compatibility, project management capabilities, code formatting and error checking functions and an online repository. It uses an easy-to-read/write script system that encourages code reuse. With the online repository, it also encourages sharing of pipelines, which enhances analysis reproducibility and accountability. For most users, PipelineDog requires no software installation. Overall, this web application provides a way to rapidly create and easily manage pipelines. PipelineDog web app is freely available at http://web.pipeline.dog. The command line version is available at http://www.npmjs.com/package/pipelinedog and online repository at http://repo.pipeline.dog. ysun@kean.edu or xing@biology.rutgers.edu or ysun@diagnoa.com. Supplementary data are available at Bioinformatics online.

  6. A Corrosion Control Manual for Rail Rapid Transit

    NASA Technical Reports Server (NTRS)

    Gilbert, L. O.; Fitzgerald, J. H., III; Menke, J. T.; Lizak, R. M. (Editor)

    1982-01-01

    This manual addresses corrosion problems in the design, contruction, and maintenance of rapid transit systems. Design and maintenance solutions are provided for each problem covered. The scope encompasses all facilities of urban rapid transit systems: structures and tracks, platforms and stations, power and signals, and cars. The types of corrosion and their causes as well as rapid transit properties are described. Corrosion control committees, and NASA, DOD, and ASTM specifications and design criteria to which reference is made in the manual are listed. A bibliography of papers and excerpts of reports is provided and a glossary of frequently used terms is included.

  7. 40 CFR Table 41 to Subpart Uuu of... - Requirements for Installation, Operation, and Maintenance of Continuous Parameter Monitoring Systems

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 12 2011-07-01 2009-07-01 true Requirements for Installation, Operation, and Maintenance of Continuous Parameter Monitoring Systems 41 Table 41 to Subpart UUU of Part 63... Sulfur Recovery Units Pt. 63, Subpt. UUU, Table 41 Table 41 to Subpart UUU of Part 63—Requirements for...

  8. Role of the primary care provider in the diagnosis and management of heartburn.

    PubMed

    Kushner, Pamela R

    2010-04-01

    Heartburn affects an estimated 42% of the US population. Often, patients are able to recognize symptoms and self-treat heartburn; however, patients with more persistent and/or troublesome symptoms should be evaluated by a physician or other healthcare provider. This review focuses on the role of the primary care provider in the diagnosis and treatment of heartburn. A search was conducted on PubMed (to November 2009) and articles relevant to the management of heartburn by a primary care provider topic were selected. Diagnostic tools, such as endoscopy, and ambulatory pH monitoring, are recommended for advanced assessment of patients with frequent heartburn to avert misdiagnosis and to identify complications of reflux disease. Over-the-counter and prescription treatments for frequent heartburn symptoms include antacids, histamine(2)-receptor antagonists (H(2)RAs), antacid/H(2)RA combinations, and proton pump inhibitors (PPIs). Among these, PPIs represent the mainstay of acute and maintenance treatment regimens in reflux disorders and are more effective than H(2)RAs for long-term use due to the development of tolerance to the latter therapy. While once-daily PPI therapy may be sufficient in most patients, a few may require twice-daily PPI therapy to alleviate their symptoms. This review is limited by its relatively narrow focus on articles cited in PubMed. The primary care provider is ideally situated to advise patients on the best treatment option for their condition and to provide follow-up care if required.

  9. 7 CFR 1730.22 - Borrower analysis.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... which could indicate deterioration in the physical or cyber condition or the operational effectiveness of the system or suggest a need for changes in security, operations or maintenance policies... AGRICULTURE ELECTRIC SYSTEM OPERATIONS AND MAINTENANCE Operations and Maintenance Requirements § 1730.22...

  10. 7 CFR 1730.22 - Borrower analysis.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... which could indicate deterioration in the physical or cyber condition or the operational effectiveness of the system or suggest a need for changes in security, operations or maintenance policies... AGRICULTURE ELECTRIC SYSTEM OPERATIONS AND MAINTENANCE Operations and Maintenance Requirements § 1730.22...

  11. 7 CFR 1730.22 - Borrower analysis.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... which could indicate deterioration in the physical or cyber condition or the operational effectiveness of the system or suggest a need for changes in security, operations or maintenance policies... AGRICULTURE ELECTRIC SYSTEM OPERATIONS AND MAINTENANCE Operations and Maintenance Requirements § 1730.22...

  12. 7 CFR 1730.22 - Borrower analysis.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... which could indicate deterioration in the physical or cyber condition or the operational effectiveness of the system or suggest a need for changes in security, operations or maintenance policies... AGRICULTURE ELECTRIC SYSTEM OPERATIONS AND MAINTENANCE Operations and Maintenance Requirements § 1730.22...

  13. 36 CFR 1222.34 - How must agencies maintain records?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ADMINISTRATION RECORDS MANAGEMENT CREATION AND MAINTENANCE OF FEDERAL RECORDS Agency Recordkeeping Requirements § 1222.34 How must agencies maintain records? Agencies must implement a records maintenance program so... electronic records, segregable. Agency records maintenance programs must: (a) Institute procedures for...

  14. Rapid Transit Subways - Maintenance Guidelines for Engineering New Installations for Reduced Maintenance

    DOT National Transportation Integrated Search

    1978-01-01

    Economic design of new subways requires optimization of installation and maintenance costs of all the major constituent items. A prerequisite for this is an awareness of the rigorous environmental and other conditions imposed on the subway. Changing ...

  15. 78 FR 77574 - Protection System Maintenance Reliability Standard

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... protection system component type, except that the maintenance program for all batteries associated with the... Electric System reliability and promoting efficiency through consolidation [of protection system-related... ITC that PRC-005-2 promotes efficiency by consolidating protection system maintenance requirements...

  16. Research requirements to reduce maintenance costs of civil helicopters

    NASA Technical Reports Server (NTRS)

    Million, D. J.; Waters, K. T.

    1978-01-01

    The maintenance problems faced by the operators of civil helicopters that result in high costs are documented. Existing technology that can be applied to reduce maintenance costs and research that should be carried out were identified. Good design practice and application of existing technology were described as having a significant impact on reducing maintenance costs immediately. The research and development that have potential for long range reduction of maintenance costs are presented.

  17. Laboratory services series: a master-slave manipulator maintenance program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jenness, R. G.; Hicks, R. E.; Wicker, C. D.

    1976-12-01

    The volume of master slave manipulator maintenance at Oak Ridge National Laboratory has necessitated the establishment of a repair facility and organization of a specially trained group of craftsmen. Emphasis on cell containment requires the use of manipulator boots and development of precise procedures for accomplishing the maintenance of 287 installed units. A very satisfactory computer programmed maintenance system has been established at the Laboratory to provide an economical approach to preventive maintenance.

  18. Considerations when using variable frequency drive technology for pond aquculture

    USDA-ARS?s Scientific Manuscript database

    Some farmers have decided to use variable frequency drives (VFDs) to control pump speed and water flow rate to reduce operational cost and costs associated with repairs and maintenance. Mixed performance issues with VFDs and electric motors have been reported. Examples include frequent drive failure...

  19. Evaluating winter/spring seeding of a native perennial bunchgrass in the sagebrush steppe

    USDA-ARS?s Scientific Manuscript database

    Sagebrush (Artemisia tridentata Nutt.) plant communities in the US Great Basin region are being severely impacted by increasingly frequent wildfires in association with the expansion of exotic annual grasses. Maintenance of native perennial bunchgrasses is key to controlling annual grass expansion,...

  20. Sexual Harassment: Experiences of University Employees.

    ERIC Educational Resources Information Center

    Goodwin, Megan P.; And Others

    1989-01-01

    Examined Central Michigan University employees' (N=449) sexual harassment experiences through employee survey. Found that (1) more women than men reported sexual harassment; (2) most common harassers cited were male co-workers, administrators, and maintenance employees; (3) harassment most frequently attributed to working conditions and hours; (4)…

  1. An Analysis of Military Use of Commercial Satellite Communications

    DTIC Science & Technology

    2008-09-01

    frequent visits to my office (complete with hugs, throwing of stuffed animals, and random strumming of my guitar ) helped to ensure the maintenance of...policy). This option is the primary recommendation of this thesis, although the Depot 50/50 Paradigm also scored relatively high. The following

  2. The Development of Display Rule Knowledge: Linkages with Family Expressiveness and Social Competence.

    ERIC Educational Resources Information Center

    Jones, Diane Carlson; Cumberland, Amanda; Abbey, Belynda Bowling

    1998-01-01

    Two studies investigated emotional-display-rule knowledge and its associations with family expressiveness and peer competence. Findings indicated that third graders combined expression regulation with prosocial reasoning, norm-maintenance, and self-protective motives more frequently than kindergartners. Negative expressiveness was related…

  3. Invited review: technical solutions for analysis of milk constituents and abnormal milk.

    PubMed

    Brandt, M; Haeussermann, A; Hartung, E

    2010-02-01

    Information about constituents of milk and visual alterations can be used for management support in improving mastitis detection, monitoring fertility and reproduction, and adapting individual diets. Numerous sensors that gather this information are either currently available or in development. Nevertheless, there is still a need to adapt these sensors to special requirements of on-farm utilization such as robustness, calibration and maintenance, costs, operating cycle duration, and high sensitivity and specificity. This paper provides an overview of available sensors, ongoing research, and areas of application for analysis of milk constituents. Currently, the recognition of abnormal milk and the control of udder health is achieved mainly by recording electrical conductivity and changes in milk color. Further indicators of inflammation were recently investigated either to satisfy the high specificity necessary for automatic separation of milk or to create reliable alarm lists. Likewise, milk composition, especially fat:protein ratio, milk urea nitrogen content, and concentration of ketone bodies, provides suitable information about energy and protein supply, roughage fraction in the diet, and metabolic imbalances in dairy cows. In this regard, future prospects are to use frequent on-farm measurements of milk constituents for short-term automatic nutritional management. Finally, measuring progesterone concentration in milk helps farmers detect ovulation, pregnancy, and infertility. Monitoring systems for on-farm or on-line analysis of milk composition are mostly based on infrared spectroscopy, optical methods, biosensors, or sensor arrays. Their calibration and maintenance requirements have to be checked thoroughly before they can be regularly implemented on dairy farms. Copyright 2010 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  4. Emergency egress requirements for caution and warning, logistics, maintenance, and assembly stage MB-6 of Space Station Freedom

    NASA Technical Reports Server (NTRS)

    Ray, Paul S.

    1992-01-01

    The safety and survival of the crewmembers has been the prime concern of NASA. Previous studies have been conducted mainly for emergencies occurring during the operating mode of the fully assembled Station. The present study was conducted to evaluate the emergency requirements for the caution and warning, logistics, maintenance, and assembly stage MB-6 of the Station in space. Effective caution and warning is essential to achieve safe egress in emergencies. In order to survive a long period in space, the safety and emergency requirements for maintenance, logistics, and extravehicular assembly operation in space must be met.

  5. Maintenance: organizational modes, activities and health and safety. Use of a French national survey and in-situ analyses.

    PubMed

    Grusenmeyer, Corinne

    2014-12-01

    Maintenance activities are identified as critical both to operator safety and to systems safety and reliability. However, it is still difficult to identify maintenance workers in French occupational accident and disease statistics. Moreover, few analyses of these activities and of organizational changes in this field have been conducted. This paper presents two different approaches to this same issue. Analyses were aimed firstly at identifying the occupational exposures of these operators and at comparing them with occupational exposures of production staff and, secondly at developing understanding of normal real maintenance activities, i.e. maintenance activities that are normally actually carried out, while taking into account the socio-technical system and maintenance organization within which they lie. The use of the French SUMER 2003 survey shows that occupational exposures of maintenance staff to various constraints are more frequent than occupational exposures of their production colleagues. However, maintenance staff appear to have greater independence. Analyses were also conducted in a subcontracting urban public transport company, who outsources some maintenance work. Those analyses highlight a complex network of companies involved in maintenance activities, a substantial number of work interruptions and a significant fragmentation of the internal technicians' activities that can be cognitively costly, reduce anticipation possibilities and lead to incidents or accidents. Above all they underline internal technicians' contributions to the completion of outsourced interventions and interdependent relationships between the activities of the internal and the external technicians. Outsourcing maintenance interventions thus raises the question of risks associated with the interdependence of actual work activities undertaken by the different types of staff, since they contribute to the same maintenance intervention. This study therefore pinpoints the need to integrate inter-organizational interactions in order to understand the variability of maintenance activities and its relationships with reliability and safety. In this respect, some suggestions are provided with a prevention aim. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Cluster man/system design requirements and verification. [for Skylab program

    NASA Technical Reports Server (NTRS)

    Watters, H. H.

    1974-01-01

    Discussion of the procedures employed for determining the man/system requirements that guided Skylab design, and review of the techniques used for implementing the man/system design verification. The foremost lesson learned from the design need anticipation and design verification experience is the necessity to allow for human capabilities of in-flight maintenance and repair. It is now known that the entire program was salvaged by a series of unplanned maintenance and repair events which were implemented in spite of poor design provisions for maintenance.

  7. Command and Telemetry Latency Effects on Operator Performance during International Space Station Robotics Operations

    NASA Technical Reports Server (NTRS)

    Currie, Nancy J.; Rochlis, Jennifer

    2004-01-01

    International Space Station (ISS) operations will require the on-board crew to perform numerous robotic-assisted assembly, maintenance, and inspection activities. Current estimates for some robotically performed maintenance timelines are disproportionate and potentially exceed crew availability and duty times. Ground-based control of the ISS robotic manipulators, specifically the Special Purpose Dexterous Manipulator (SPDM), is being examined as one potential solution to alleviate the excessive amounts of crew time required for extravehicular robotic maintenance and inspection tasks.

  8. Functional Characterization of the Cingulo-Opercular Network in the Maintenance of Tonic Alertness

    PubMed Central

    Sadaghiani, Sepideh; D'Esposito, Mark

    2015-01-01

    The complex processing architecture underlying attentional control requires delineation of the functional role of different control-related brain networks. A key component is the cingulo-opercular (CO) network composed of anterior insula/operculum, dorsal anterior cingulate cortex, and thalamus. Its function has been particularly difficult to characterize due to the network's pervasive activity and frequent co-activation with other control-related networks. We previously suggested this network to underlie intrinsically maintained tonic alertness. Here, we tested this hypothesis by separately manipulating the demand for selective attention and for tonic alertness in a two-factorial, continuous pitch discrimination paradigm. The 2 factors had independent behavioral effects. Functional imaging revealed that activity as well as functional connectivity in the CO network increased when the task required more tonic alertness. Conversely, heightened selective attention to pitch increased activity in the dorsal attention (DAT) network but not in the CO network. Across participants, performance accuracy showed dissociable correlation patterns with activity in the CO, DAT, and fronto-parietal (FP) control networks. These results support tonic alertness as a fundamental function of the CO network. They further the characterization of this function as the effortful process of maintaining cognitive faculties available for current processing requirements. PMID:24770711

  9. 49 CFR 393.25 - Requirements for lamps other than head lamps.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... booms, backhoes, and winches) prevents compliance with this paragraph by any required lamp, an auxiliary... SAE J845—Optical Warning Devices for Authorized Emergency, Maintenance and Service Vehicles, May 1997... Authorized Emergency, Maintenance and Service Vehicles, January 2005. Amber gaseous discharge warning lamps...

  10. 49 CFR 393.25 - Requirements for lamps other than head lamps.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... booms, backhoes, and winches) prevents compliance with this paragraph by any required lamp, an auxiliary... SAE J845—Optical Warning Devices for Authorized Emergency, Maintenance and Service Vehicles, May 1997... Authorized Emergency, Maintenance and Service Vehicles, January 2005. Amber gaseous discharge warning lamps...

  11. 77 FR 51880 - Requirements for Maintenance of Inspections, Tests, Analyses, and Acceptance Criteria

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-28

    ... Maintenance of Inspections, Tests, Analyses, and Acceptance Criteria AGENCY: Nuclear Regulatory Commission... construction activities through inspections, tests, analyses, and acceptance criteria (ITAAC) under a combined... inspections, tests, or analyses were performed as required, or that acceptance criteria are met, and to notify...

  12. 40 CFR 63.6625 - What are my monitoring, installation, collection, operation, and maintenance requirements?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., operate, and maintain a CEMS to monitor CO and either O2 or CO2 according to the requirements in... program must be part of the maintenance plan for the engine. (j) If you own or operate a stationary SI...

  13. 40 CFR 63.9525 - What are the installation, operation, and maintenance requirements for my weight measurement device?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., and maintenance requirements for my weight measurement device? 63.9525 Section 63.9525 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for...

  14. 49 CFR 393.25 - Requirements for lamps other than head lamps.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... booms, backhoes, and winches) prevents compliance with this paragraph by any required lamp, an auxiliary... SAE J845—Optical Warning Devices for Authorized Emergency, Maintenance and Service Vehicles, May 1997... Authorized Emergency, Maintenance and Service Vehicles, January 2005. Amber gaseous discharge warning lamps...

  15. 49 CFR 393.25 - Requirements for lamps other than head lamps.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... booms, backhoes, and winches) prevents compliance with this paragraph by any required lamp, an auxiliary... SAE J845—Optical Warning Devices for Authorized Emergency, Maintenance and Service Vehicles, May 1997... Authorized Emergency, Maintenance and Service Vehicles, January 2005. Amber gaseous discharge warning lamps...

  16. 49 CFR 393.25 - Requirements for lamps other than head lamps.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... booms, backhoes, and winches) prevents compliance with this paragraph by any required lamp, an auxiliary... SAE J845—Optical Warning Devices for Authorized Emergency, Maintenance and Service Vehicles, May 1997... Authorized Emergency, Maintenance and Service Vehicles, January 2005. Amber gaseous discharge warning lamps...

  17. Distinct Amino Acid Compositional Requirements for Formation and Maintenance of the [PSI+] Prion in Yeast

    PubMed Central

    MacLea, Kyle S.; Paul, Kacy R.; Ben-Musa, Zobaida; Waechter, Aubrey; Shattuck, Jenifer E.; Gruca, Margaret

    2014-01-01

    Multiple yeast prions have been identified that result from the structural conversion of proteins into a self-propagating amyloid form. Amyloid-based prion activity in yeast requires a series of discrete steps. First, the prion protein must form an amyloid nucleus that can recruit and structurally convert additional soluble proteins. Subsequently, maintenance of the prion during cell division requires fragmentation of these aggregates to create new heritable propagons. For the Saccharomyces cerevisiae prion protein Sup35, these different activities are encoded by different regions of the Sup35 prion domain. An N-terminal glutamine/asparagine-rich nucleation domain is required for nucleation and fiber growth, while an adjacent oligopeptide repeat domain is largely dispensable for prion nucleation and fiber growth but is required for chaperone-dependent prion maintenance. Although prion activity of glutamine/asparagine-rich proteins is predominantly determined by amino acid composition, the nucleation and oligopeptide repeat domains of Sup35 have distinct compositional requirements. Here, we quantitatively define these compositional requirements in vivo. We show that aromatic residues strongly promote both prion formation and chaperone-dependent prion maintenance. In contrast, nonaromatic hydrophobic residues strongly promote prion formation but inhibit prion propagation. These results provide insight into why some aggregation-prone proteins are unable to propagate as prions. PMID:25547291

  18. Belatacept: a novel biologic for maintenance immunosuppression after renal transplantation.

    PubMed

    Martin, Spencer T; Tichy, Eric M; Gabardi, Steven

    2011-04-01

    In the past decade, the availability of new immunosuppressive maintenance therapies for use in solid organ transplantation has remained limited. Patients and clinicians have relied on immunosuppressive drugs that require a significant amount of therapeutic monitoring and are associated with a variety of adverse effects that affect both quality of life and allograft function. Belatacept is an investigational intravenous biologic agent for long-term use in renal transplant recipients. The costimulatory pathway (signal 2) of T-cell activation and proliferation is produced by stimulation of the T-cell surface marker, CD28, and is essential to the immune system's cellular response and ability to recognize an allograft as foreign. Belatacept is a potent antagonist of B7-1 (CD80) and B7-2 (CD86) ligands present on antigen-presenting cells that are responsible for activation of CD28. Recent phase III trials describe various dosing strategies of belatacept versus a standard cyclosporine protocol in recipients of both living- and deceased-donor renal transplants, as well as in patients receiving kidneys transplanted from extended-criteria donors. Compared with cyclosporine, belatacept has been shown to be noninferior in both patient and allograft survival rates. However, the rate of biopsy-proven acute cellular rejection occurred more frequently in the belatacept groups. Also, compared with standard calcineurin-based regimens, the risk of posttransplant lymphoproliferative disorder is increased in patients receiving belatacept, with the greatest risk in transplant recipients who are Epstein-Barr virus seronegative before transplantation. However, this investigational immunosuppressive agent may avert common adverse effects experienced with standard immunosuppressive protocols including renal dysfunction, metabolic disorders, neurotoxicities, glucose abnormalities, and cosmetic effects. More data on the long-term risks of belatacept are needed to better define its role as immunosuppressive maintenance therapy. Aside from an increased risk of malignancy, belatacept's limited adverse-effect profile and convenient dosing strategy may make it an attractive option for immuno-suppressive maintenance for both the patient and clinician.

  19. 14 CFR Appendix A to Part 33 - Instructions for Continued Airworthiness

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... degree of complexity requiring specialized maintenance techniques, test equipment, or expertise. The... Limitations section must also prescribe the mandatory post-flight inspections and maintenance actions... adequacy of the instructions for mandatory post-flight inspections and maintenance actions prescribed under...

  20. 14 CFR Appendix A to Part 33 - Instructions for Continued Airworthiness

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... degree of complexity requiring specialized maintenance techniques, test equipment, or expertise. The... Limitations section must also prescribe the mandatory post-flight inspections and maintenance actions... adequacy of the instructions for mandatory post-flight inspections and maintenance actions prescribed under...

  1. 14 CFR Appendix A to Part 33 - Instructions for Continued Airworthiness

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... degree of complexity requiring specialized maintenance techniques, test equipment, or expertise. The... Limitations section must also prescribe the mandatory post-flight inspections and maintenance actions... adequacy of the instructions for mandatory post-flight inspections and maintenance actions prescribed under...

  2. 29 CFR 2520.107-1 - Use of electronic media for maintenance and retention of records.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false Use of electronic media for maintenance and retention of....107-1 Use of electronic media for maintenance and retention of records. (a) Scope and purpose... media for the maintenance and retention of records required to be kept under sections 107 and 209 of...

  3. 29 CFR 2520.107-1 - Use of electronic media for maintenance and retention of records.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Use of electronic media for maintenance and retention of....107-1 Use of electronic media for maintenance and retention of records. (a) Scope and purpose... media for the maintenance and retention of records required to be kept under sections 107 and 209 of...

  4. 29 CFR 2520.107-1 - Use of electronic media for maintenance and retention of records.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false Use of electronic media for maintenance and retention of....107-1 Use of electronic media for maintenance and retention of records. (a) Scope and purpose... media for the maintenance and retention of records required to be kept under sections 107 and 209 of...

  5. 29 CFR 2520.107-1 - Use of electronic media for maintenance and retention of records.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Use of electronic media for maintenance and retention of....107-1 Use of electronic media for maintenance and retention of records. (a) Scope and purpose... media for the maintenance and retention of records required to be kept under sections 107 and 209 of...

  6. 29 CFR 2520.107-1 - Use of electronic media for maintenance and retention of records.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Use of electronic media for maintenance and retention of....107-1 Use of electronic media for maintenance and retention of records. (a) Scope and purpose... media for the maintenance and retention of records required to be kept under sections 107 and 209 of...

  7. Analysis of Maintenance Service Contracts for Dump Trucks Used in Mining Industry with Simulation Approach

    NASA Astrophysics Data System (ADS)

    Dymasius, A.; Wangsaputra, R.; Iskandar, B. P.

    2016-02-01

    A mining company needs high availability of dump trucks used to haul mining materials. As a result, an effective maintenance action is required to keep the dump trucks in a good condition and hence reducing failure and downtime of the dump trucks. To carry out maintenance in-house requires a high intensive maintenance facility and high skilled maintenance specialists. Often, outsourcing maintenance is an economic option for the company. An external agent takes a proactive action with offering some maintenance contract options to the owner. The decision problem for the owner is to decide the best option and for the agent is to determine the optimal price for each option offered. A non-cooperative game-theory is used to formulate the decision problems for the owner and the agent. We consider that failure pattern of each truck follows a non-homogeneous Poisson process (NHPP) and a queueing theory with multiple servers is used to estimate the downtime. As it involves high complexity to model downtime using a queueing theory, then in this paper we use a simulation method. Furthermore, we conduct experiment to seek for the best number of maintenance facilities (servers) which minimises maintenance and penalty costs incurred to the agent.

  8. A Requirements Analysis for an Integrated Maintenance Information System Application Into Theater Air Control System Maintenance

    DTIC Science & Technology

    1994-09-01

    133 v List of Tables Table Page 1. Line Item Changes in Proposed Ground TACS SSS Matrix...39 2. Percentage of Line Item Changes in Proposed SSS Matrix for G round T A C S...modified to meet Theater Air Control System requirements. The small amount of changes required to modify the aircraft matrix in order to satisfy ground

  9. Solid Waste Management Units And Areas Of Concern Annual Long-Term Monitoring & Maintenance Report For Calendar Year 2016.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dotson, Patrick Wells; Little, Bonnie Colleen

    Long-term controls were maintained at 21 Solid Waste Management Units (SWMUs) and Areas of Concern (AOCs) in accordance with the requirements of the “Long-Term Monitoring and Maintenance Plan for SWMUs and AOCs Granted Corrective Action Complete with Controls” in Attachment M of the Resource Conservation and Recovery Act Facility Operating Permit, which took effect February 26, 2015. Maintenance and controls at these SWMUs and AOCs are described and documented in this report. Conditions requiring maintenance or repair activities were not identified for any of the inspected SWMUs or AOCs. Based upon the inspections performed and site conditions observed, the administrativemore » and physical institutional controls in place at the SWMUs and AOCs are effectively providing continued protection of human health and the environment. This report does not present monitoring and maintenance activities for SWMU 76, the Mixed Waste Landfill; those activities adhere to the approved MWL LTMM Plan, Section 4.8.1 requiring a separate annual report which will be submitted to the NMED by June 30, 2017.« less

  10. 14 CFR 171.43 - Requests for IFR procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... organization and a maintenance manual that meets the requirements of § 171.51. (4) A statement of intent to... operational reliability and an acceptable standard of performance. Previous equivalent operational experience... owner of the results and of any required changes in the facility or the maintenance manual or...

  11. 77 FR 32439 - Airworthiness Directives; Bombardier Inc. Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-01

    ... Temporary Revision has been made to Part 2 of the Maintenance Requirements Manual (MRM) to revise the... the Bombardier CL-600-2B19 MRM. The actions described in this service information are intended to... Continued Airworthiness of the Canadair Regional Jet Maintenance Requirements Manual (MRM), Part 2, Appendix...

  12. 49 CFR 180.509 - Requirements for inspection and test of specification tank cars.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... specification tank cars. 180.509 Section 180.509 Transportation Other Regulations Relating to Transportation... REGULATIONS CONTINUING QUALIFICATION AND MAINTENANCE OF PACKAGINGS Qualification and Maintenance of Tank Cars § 180.509 Requirements for inspection and test of specification tank cars. (a) General. (1) Each tank...

  13. 49 CFR 180.509 - Requirements for inspection and test of specification tank cars.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... specification tank cars. 180.509 Section 180.509 Transportation Other Regulations Relating to Transportation...) CONTINUING QUALIFICATION AND MAINTENANCE OF PACKAGINGS Qualification and Maintenance of Tank Cars § 180.509 Requirements for inspection and test of specification tank cars. (a) General. (1) Each tank car facility shall...

  14. 78 FR 23627 - Agency Information Collection Activities: Requests for Comments; Clearance of Renewed Approval of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... of 1995, FAA invites public comments about our intention to request the Office of Management and... whether required maintenance actions have been accomplished on light-sport aircraft. The information is... aircraft. The information is used by FAA safety inspectors in determining whether required maintenance...

  15. 40 CFR 63.1451 - How do I demonstrate initial compliance with the emission limitations, work practice standards...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... written operation and maintenance plan required under § 63.1447(b) detailed descriptions of the procedures... with the emission limitations, work practice standards, and operation and maintenance requirements that... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE...

  16. 40 CFR 63.1451 - How do I demonstrate initial compliance with the emission limitations, work practice standards...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... written operation and maintenance plan required under § 63.1447(b) detailed descriptions of the procedures... with the emission limitations, work practice standards, and operation and maintenance requirements that... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE...

  17. 40 CFR 63.1451 - How do I demonstrate initial compliance with the emission limitations, work practice standards...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... written operation and maintenance plan required under § 63.1447(b) detailed descriptions of the procedures... with the emission limitations, work practice standards, and operation and maintenance requirements that... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE...

  18. 40 CFR 63.1451 - How do I demonstrate initial compliance with the emission limitations, work practice standards...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... written operation and maintenance plan required under § 63.1447(b) detailed descriptions of the procedures... compliance with the emission limitations, work practice standards, and operation and maintenance requirements... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE...

  19. 40 CFR 63.1451 - How do I demonstrate initial compliance with the emission limitations, work practice standards...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... written operation and maintenance plan required under § 63.1447(b) detailed descriptions of the procedures... compliance with the emission limitations, work practice standards, and operation and maintenance requirements... (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE...

  20. 46 CFR 120.200 - General design, installation, and maintenance requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false General design, installation, and maintenance requirements. 120.200 Section 120.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150 PASSENGERS OR WITH OVERNIGHT ACCOMMODATIONS FOR MORE THAN 49 PASSENGERS ELECTRICAL INSTALLATION General...

  1. 46 CFR 120.200 - General design, installation, and maintenance requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false General design, installation, and maintenance requirements. 120.200 Section 120.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150 PASSENGERS OR WITH OVERNIGHT ACCOMMODATIONS FOR MORE THAN 49 PASSENGERS ELECTRICAL INSTALLATION General...

  2. 40 CFR 63.7945 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 13 2011-07-01 2011-07-01 false What are my monitoring installation, operation, and maintenance requirements? 63.7945 Section 63.7945 Protection of Environment ENVIRONMENTAL... Remediation Continuous Monitoring Systems § 63.7945 What are my monitoring installation, operation, and...

  3. 40 CFR 63.7945 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 14 2012-07-01 2011-07-01 true What are my monitoring installation, operation, and maintenance requirements? 63.7945 Section 63.7945 Protection of Environment ENVIRONMENTAL... Remediation Continuous Monitoring Systems § 63.7945 What are my monitoring installation, operation, and...

  4. 40 CFR 63.7945 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 14 2014-07-01 2014-07-01 false What are my monitoring installation, operation, and maintenance requirements? 63.7945 Section 63.7945 Protection of Environment ENVIRONMENTAL... Remediation Continuous Monitoring Systems § 63.7945 What are my monitoring installation, operation, and...

  5. 40 CFR 63.7945 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 13 2010-07-01 2010-07-01 false What are my monitoring installation, operation, and maintenance requirements? 63.7945 Section 63.7945 Protection of Environment ENVIRONMENTAL... Remediation Continuous Monitoring Systems § 63.7945 What are my monitoring installation, operation, and...

  6. 40 CFR 63.7945 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 14 2013-07-01 2013-07-01 false What are my monitoring installation, operation, and maintenance requirements? 63.7945 Section 63.7945 Protection of Environment ENVIRONMENTAL... Remediation Continuous Monitoring Systems § 63.7945 What are my monitoring installation, operation, and...

  7. 45 CFR 149.350 - Maintenance of records.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Maintenance of records. 149.350 Section 149.350 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS... (but not limited to) the use of electronic media. (d) The sponsor must require its health insurance...

  8. 45 CFR 149.350 - Maintenance of records.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Maintenance of records. 149.350 Section 149.350 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS... (but not limited to) the use of electronic media. (d) The sponsor must require its health insurance...

  9. 77 FR 66361 - Reserve Requirements of Depository Institutions: Reserves Simplification

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-05

    ... simplifications related to the administration of reserve requirements: 1. Create a common two-week maintenance... earlier than it would implement the common maintenance period and the penalty-free band. The Board... effective July 12, 2012. The Board announced January 24, 2013, as the implementation date for the common two...

  10. 29 CFR 403.7 - Maintenance and retention of records.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...-MANAGEMENT STANDARDS LABOR ORGANIZATION ANNUAL FINANCIAL REPORTS § 403.7 Maintenance and retention of records. Every person required to file any report under this part shall maintain records on the matters required to be reported which will provide in sufficient detail the necessary basic information and data from...

  11. 34 CFR 461.42 - What is the maintenance of effort requirement?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What is the maintenance of effort requirement? 461.42 Section 461.42 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION STATE-ADMINISTERED BASIC GRANT...

  12. 34 CFR 461.42 - What is the maintenance of effort requirement?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What is the maintenance of effort requirement? 461.42 Section 461.42 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION STATE-ADMINISTERED BASIC GRANT...

  13. 34 CFR 461.42 - What is the maintenance of effort requirement?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false What is the maintenance of effort requirement? 461.42 Section 461.42 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION STATE-ADMINISTERED BASIC GRANT...

  14. 34 CFR 461.42 - What is the maintenance of effort requirement?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false What is the maintenance of effort requirement? 461.42 Section 461.42 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION STATE-ADMINISTERED BASIC GRANT...

  15. 34 CFR 461.42 - What is the maintenance of effort requirement?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false What is the maintenance of effort requirement? 461.42 Section 461.42 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION STATE-ADMINISTERED BASIC GRANT...

  16. 14 CFR Appendix A to Part 33 - Instructions for Continued Airworthiness

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... features and data to the extent necessary for maintenance or preventive maintenance. (2) A detailed... limits, maximum continuous power or thrust, bleed air, and power extraction required for a relevant... Airworthiness consist of multiple documents, the section required under this paragraph must be included in the...

  17. 14 CFR Appendix A to Part 33 - Instructions for Continued Airworthiness

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... features and data to the extent necessary for maintenance or preventive maintenance. (2) A detailed... limits, maximum continuous power or thrust, bleed air, and power extraction required for a relevant... Airworthiness consist of multiple documents, the section required under this paragraph must be included in the...

  18. 40 CFR 1054.125 - What maintenance instructions must I give to buyers?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... schedule cleaning or changing air filters or changing spark plugs at the least frequent interval described... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, SMALL NONROAD SPARK-IGNITION ENGINES AND... aftertreatment devices, pulse-air valves, fuel injectors, oxygen sensors, electronic control units, superchargers...

  19. 40 CFR 1054.125 - What maintenance instructions must I give to buyers?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... schedule cleaning or changing air filters or changing spark plugs at the least frequent interval described... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW, SMALL NONROAD SPARK-IGNITION ENGINES AND... aftertreatment devices, pulse-air valves, fuel injectors, oxygen sensors, electronic control units, superchargers...

  20. Grassland Smoke Emission Measurement Supporting Multi-Modeling Framework Simulation of Rangeland Burning Practices for the Kansas Flint Hills Fire Experiment

    EPA Science Inventory

    Historically, frequent wildfires were essential for the maintenance of native prairie fire adapted ecosystems. Today prescribed fires are used to control invasive woody species and potentially improve forage production in these same prairie ecosystems for the beef-cattle industry...

  1. Capital and Operating Cost of Small Arsenic Removal System and their Most Frequent Maintenance Problems

    EPA Science Inventory

    This presentation will first summarize the capital and operating cost of treatment systems by type and size of the systems. The treatment systems include adsorptive media (AM) systems, iron removal (IR), coagulation/filtration (CF), ion exchange (IX) systems, and point-of-use rev...

  2. Sleep in Children with Asperger Syndrome

    ERIC Educational Resources Information Center

    Paavonen, E. Juulia; Vehkalahti; Kimmo; Vanhala, Raija; von Wendt, Lennart; Nieminen-von Wendt, Taina; Aronen, Eeva T.

    2008-01-01

    The prevalence of sleep disturbances in 52 children with Asperger syndrome (AS) as compared with 61 healthy controls (all subjects aged 5-17 years) was investigated. Problems with sleep onset and maintenance, sleep-related fears, negative attitudes toward sleeping, and daytime somnolence were more frequent among children with AS than among…

  3. 14 CFR 171.153 - Requests for IFR procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... and maintenance manual that meets the requirement of § 171.161. (4) A statement of intention to meet... operational reliability and an acceptable standard of performance. Previous equivalent operational experience... maintenance manual or maintenance organization. The owner must then correct the deficiencies, if any, and...

  4. 45 CFR 1310.13 - Maintenance of vehicles.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Maintenance of vehicles. 1310.13 Section 1310.13... PROGRAM HEAD START TRANSPORTATION Transportation Requirements § 1310.13 Maintenance of vehicles. Each agency providing transportation services must ensure that vehicles used to provide such services are...

  5. 45 CFR 1310.13 - Maintenance of vehicles.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Maintenance of vehicles. 1310.13 Section 1310.13... PROGRAM HEAD START TRANSPORTATION Transportation Requirements § 1310.13 Maintenance of vehicles. Each agency providing transportation services must ensure that vehicles used to provide such services are...

  6. 45 CFR 1310.13 - Maintenance of vehicles.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Maintenance of vehicles. 1310.13 Section 1310.13... PROGRAM HEAD START TRANSPORTATION Transportation Requirements § 1310.13 Maintenance of vehicles. Each agency providing transportation services must ensure that vehicles used to provide such services are...

  7. 77 FR 67584 - Air Carrier Contract Maintenance Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-13

    ...-certificated repair facilities, and the air carriers' outsourcing of maintenance. In each of those reports... maintenance outsourcing practices (Recommendation 2). \\3\\ Review of Air Carriers' Use of Aircraft Repair... (Recommendation 7). \\4\\ Air Carrier's Outsourcing Use of Non-Certificated Repair Facilities, Report No. AV-2006...

  8. Monitoring Strategies in Permeable Pavement Systems to Optimize Maintenance Scheduling

    EPA Science Inventory

    As the surface in a permeable pavement system clogs and performance decreases, maintenance is required to preserve the design function. Currently, guidance is limited for scheduling maintenance on an as needed basis. Previous research has shown that surface clogging in a permea...

  9. Monitoring Strategies in Permeable Pavement Systems to Optimize Maintenance Scheduling - abstract

    EPA Science Inventory

    As the surface in a permeable pavement system clogs and performance decreases, maintenance is required to preserve the design function. Currently, guidance is limited for scheduling maintenance on an as needed basis. Previous research has shown that surface clogging in a permea...

  10. Discourse Coherence and Cognition after Stroke: A Dual Task Study

    ERIC Educational Resources Information Center

    Rogalski, Yvonne; Altmann, Lori J. P.; Plummer-D'Amato, Prudence; Behrman, Andrea L.; Marsiske, Michael

    2010-01-01

    Several researchers have suggested that the maintenance of global coherence (topic maintenance) and local coherence (maintenance between utterances) in discourse requires cognitive resources. This study directly tests this hypothesis by examining the relationship between cognitive variables and coherence in narrative discourse produced by…

  11. [Medical therapy of inflammatory bowel diseases: Crohn's disease].

    PubMed

    Lakatos, László; Lakatos, Péter László

    2007-06-17

    The therapy of inflammatory bowel diseases is based on 5-aminosalicylates (5-ASAs) that are the forefront of treatment of mild-to-moderate active disease and maintenance; steroids are used for the treatment of moderate-to-severe active disease; immunosuppressives and sometimes antibiotics in moderate-to-severe disease; maintenance and for the treatment of selected complications. The last few years have witnessed a significant change in the treatment of Crohn's disease. Based on evidence from new clinical studies and recent meta-analyses, the role of and indications for conventional therapy have been reassessed. The 5-ASAs are nowadays less frequently used in both active disease and maintenance therapy. Instead, budesonide has been introduced in the treatment of mild-to-moderate ileal disease. Besides the modest use of 5-ASAs, steroids are prescribed for active colonic disease. Immunosuppressives, especially azathioprine, are more commonly used in moderate-to-severe disease as well as in maintenance. The preferred maintenance regimen following medically- and surgically-induced remission, in addition to relationship between medical and surgical therapies, has also changed. The recent introduction of new "biological" therapy represents a major, promising change in the therapy of resistant and penetrating disease.

  12. Deriving the Cost of Software Maintenance for Software Intensive Systems

    DTIC Science & Technology

    2011-08-29

    more of software maintenance). Figure 4. SEER-SEM Maintenance Effort by Year Report (Reifer, Allen, Fersch, Hitchings, Judy , & Rosa, 2010...understand the linear relationship between two variables. The formula for the simple Pearson product-moment correlation is represented in Equation 5...standardization is required across the software maintenance community in order to ensure that the data being recorded can be employed beyond the agency or

  13. Laboratory equipment maintenance contracts.

    PubMed

    Boudreau, D A; Scheer, W D; Catrou, P G

    1985-12-01

    The increasing level of technical sophistication and complexity found in clinical laboratory instrumentation today more than ever demands careful attention to maintenance service needs. The time-worn caution for careful definition of requirements for acquisition of a system should also carry over to acquisition of maintenance service. Guidelines are presented for specifications of terms and conditions for maintenance service from the perspective of the laboratorian in the automated clinical laboratory.

  14. Community pharmacy and mail order cost and utilization for 90-day maintenance medication prescriptions.

    PubMed

    Khandelwal, Nikhil; Duncan, Ian; Rubinstein, Elan; Ahmed, Tamim; Pegus, Cheryl

    2012-04-01

    Pharmacy benefit management (PBM) companies promote mail order programs that typically dispense 90-day quantities of maintenance medications, marketing this feature as a key cost containment strategy to address plan sponsors' rising prescription drug expenditures. In recent years, community pharmacies have introduced 90-day programs that provide similar cost advantages, while allowing these prescriptions to be dispensed at the same pharmacies that patients frequent for 30-day quantities. To compare utilization rates and corresponding costs associated with obtaining 90-day prescriptions at community and mail order pharmacies for payers that offer equivalent benefits in different 90-day dispensing channels. We performed a retrospective, cross-sectional investigation using pharmacy claims and eligibility data from employer group clients of a large PBM between January 2008 and September 2010. We excluded the following client types: government, third-party administrators, schools, hospitals, 340B (federal drug pricing), employers in Puerto Rico, and miscellaneous clients for which the PBM provided billing services (e.g., the pharmacy's loyalty card program members). All employer groups in the sample offered 90-day community pharmacy and mail order dispensing and received benefits management services, such as formulary management and mail order pharmacy, from the PBM. We further limited the sample to employer groups that offered equivalent benefits for community pharmacy and mail order, defined as groups in which the mean and median copayments per claim for community and mail order pharmacy, by tier, differed by no more than 5%. Enrollees in the sample were required to have a minimum of 6 months of eligibility in each calendar year but were not required to have filled a prescription in any year. We evaluated pharmacy costs and utilization for a market basket of 14 frequently dispensed therapeutic classes of maintenance medications. The proportional share of claims for each therapeutic class in the mail order channel was used to weight the results for the community pharmacy channel. Using ordinary least squares regression models, we controlled for differences between channel users with respect to the following confounding factors: age, gender, presence or absence of each of the top 11 drug-inferred conditions (e.g., asthma/chronic obstructive pulmonary disease, cardiovascular disease), drug mix, and calendar year. We calculated estimated predicted means holding all covariates at their mean values. For both 90-day dispensing channels, we calculated number of 90-day claims per member per year (PMPY) and cost per pharmacy claim, with all claims counts adjusted to 30-day equivalents (i.e., number of 90-day claims × 3). Differences were compared using t-tests for statistical significance. Of 355 PBM clients prior to exclusions, 72 unique employers covering 644,071 unique members (range of approximately 100 to more than 100,000 members per employer) were included in the analysis. On an unadjusted basis, community pharmacies represented 80.8% of 90-day market basket claims (in 30-day equivalents: 3.97 claims PMPY vs. 0.95 in mail order) and 77.2% of total allowed charges. After adjustments for therapeutic group mix and patient characteristics, predicted mean pharmacy claim counts PMPY were 4.09 for community pharmacy compared with 0.85 for mail order (P  less than  0.001). Predicted mean allowed charges per claim for community and mail order pharmacies did not significantly differ ($49.03 vs. $50.04, respectively, P = 0.202). When offered maintenance medications through community and mail order pharmacies on a benefit-equivalent basis, commercially insured employees and their dependents utilized the community pharmacy channel more frequently by a margin of more than 4 to 1 in terms of claims PMPY. Overall allowed charges per claim for community and mail order pharmacy did not significantly differ.

  15. 14 CFR 147.1 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OTHER CERTIFICATED AGENCIES AVIATION MAINTENANCE TECHNICIAN SCHOOLS General § 147.1 Applicability. This part prescribes the requirements for issuing aviation maintenance technician school certificates and...

  16. Oncogenic NRAS, Required for Pathogenesis of Embryonic Rhabdomyosarcoma, Relies upon the HMGA2–IGF2BP2 Pathway

    PubMed Central

    Li, Zhizhong; Zhang, Yunyu; Ramanujan, Krishnan; Ma, Yan; Kirsch, David G.; Glass, David J.

    2013-01-01

    Embryonic rhabdomyosarcoma (ERMS) is the most common soft-tissue tumor in children. Here, we report the identification of the minor groove DNA-binding factor high mobility group AT-hook 2 (HMGA2) as a driver of ERMS development. HMGA2 was highly expressed in normal myoblasts and ERMS cells, where its expression was essential to maintain cell proliferation, survival in vitro, and tumor outgrowth in vivo. Mechanistic investigations revealed that upregulation of the insulin–like growth factor (IGF) mRNA-binding protein IGF2BP2 was critical for HMGA2 action. In particular, IGF2BP2 was essential for mRNA and protein stability of NRAS, a frequently mutated gene in ERMS. shRNA-mediated attenuation of NRAS or pharmacologic inhibition of the MAP-ERK kinase (MEK)/extracellular signal-regulated kinase (ERK) effector pathway showed that NRAS and NRAS-mediated signaling was required for tumor maintenance. Taken together, these findings implicate the HMGA2–IGFBP2–NRAS signaling pathway as a critical oncogenic driver in ERMS. PMID:23536553

  17. Sensitivity Study for Long Term Reliability

    NASA Technical Reports Server (NTRS)

    White, Allan L.

    2008-01-01

    This paper illustrates using Markov models to establish system and maintenance requirements for small electronic controllers where the goal is a high probability of continuous service for a long period of time. The system and maintenance items considered are quality of components, various degrees of simple redundancy, redundancy with reconfiguration, diagnostic levels, periodic maintenance, and preventive maintenance. Markov models permit a quantitative investigation with comparison and contrast. An element of special interest is the use of conditional probability to study the combination of imperfect diagnostics and periodic maintenance.

  18. Master--slave manipulators and remote maintenance at the Oak Ridge National Laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jenness, R.G.; Wicker, C.D.

    1975-01-01

    The volume of master-slave manipulator maintenance at Oak Ridge National Laboratory has necessitated the establishment of a repair facility and the organization of a specially trained group of craftsmen. Emphasis on cell containment requires the use of manipulator boots and the development of precise procedures for accomplishing the maintenance of 283 installed units. To provide the most economical type of preventive maintenance, a very satisfactory computer- programmed maintenance system has been established at the Laboratory. (auth)

  19. 76 FR 61638 - Airworthiness Directives; 328 Support Services GmbH (Type Certificate Previously Held by AvCraft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ... accepted during the latest Candidate Maintenance Coordination Committee meeting. This review resulted in... maintenance requirements] CMR** repetitive inspections, which have been identified as mandatory actions for... Maintenance Coordination Committee meeting. This review resulted in reduced inspection intervals, specifically...

  20. 77 FR 60323 - Airworthiness Directives; DASSUALT AVIATION Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... 50 (MF50) type design are included in Dassault Aviation Myst[egrave]re-Falcon 50 Aircraft Maintenance.... Compliance with this check is required by EASA AD 2010-0080. The maintenance tasks and airworthiness... manufacturer revision to the airplane maintenance manual (AMM) that introduces new or more restrictive...

  1. 14 CFR 21.445 - Maintenance of eligibility.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Maintenance of eligibility. 21.445 Section 21.445 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... Maintenance of eligibility. The DAS shall continue to meet the requirements for issue of the authorization or...

  2. 14 CFR 21.445 - Maintenance of eligibility.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Maintenance of eligibility. 21.445 Section 21.445 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... Maintenance of eligibility. The DAS shall continue to meet the requirements for issue of the authorization or...

  3. 47 CFR 80.96 - Maintenance tests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Maintenance tests. 80.96 Section 80.96 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES STATIONS IN THE MARITIME SERVICES Operating Requirements and Procedures Operating Procedures-General § 80.96 Maintenance tests. Stations are authorized to...

  4. Use of Time Domain Reflectometers (TDRs) in Permeable Pavement Systems to Predict Maintenance Needs and Effectiveness

    EPA Science Inventory

    As the surface in permeable pavement systems clogs, infiltration capacity decreases, so maintenance is required to maintain hydrologic performance. There is limited direct guidance for determining when maintenance is needed to prevent surface runoff bypass. Research is being co...

  5. 10 CFR 61.29 - Post-closure observation and maintenance.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Post-closure observation and maintenance. 61.29 Section 61.29 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.29 Post-closure observation and maintenance. Following completion of closure...

  6. 10 CFR 61.29 - Post-closure observation and maintenance.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Post-closure observation and maintenance. 61.29 Section 61.29 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.29 Post-closure observation and maintenance. Following completion of closure...

  7. 10 CFR 61.29 - Post-closure observation and maintenance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Post-closure observation and maintenance. 61.29 Section 61.29 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.29 Post-closure observation and maintenance. Following completion of closure...

  8. 10 CFR 61.29 - Post-closure observation and maintenance.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Post-closure observation and maintenance. 61.29 Section 61.29 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.29 Post-closure observation and maintenance. Following completion of closure...

  9. 10 CFR 61.29 - Post-closure observation and maintenance.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Post-closure observation and maintenance. 61.29 Section 61.29 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.29 Post-closure observation and maintenance. Following completion of closure...

  10. Daily corticosteroids reduce infection-associated relapses in frequently relapsing nephrotic syndrome: a randomized controlled trial.

    PubMed

    Gulati, Ashima; Sinha, Aditi; Sreenivas, Vishnubhatla; Math, Aparna; Hari, Pankaj; Bagga, Arvind

    2011-01-01

    Relapses of nephrotic syndrome often follow minor infections, commonly of the upper respiratory tract. Daily administration of maintenance prednisolone during intercurrent infections was examined to determine whether the treatment reduces relapse rates in children with frequently relapsing nephrotic syndrome. In a randomized controlled trial (nonblind, parallel group, tertiary-care hospital), 100 patients with idiopathic, frequently relapsing nephrotic syndrome eligible for therapy with prolonged low-dose, alternate-day prednisolone with or without levamisole were randomized to either receive their usual dose of alternate-day prednisolone daily for 7 days during intercurrent infections (intervention group) or continue alternate-day prednisolone (controls). Primary outcome was assessed by comparing the rates of infection-associated relapses at 12-month follow-up. Secondary outcomes were the frequency of infections and the cumulative amount of prednisolone received in both groups. Patients in the intervention group showed significantly lower infection-associated (rate difference, 0.7 episodes/patient per year; 95% confidence intervals [CI] 0.3, 1.1) and lower total relapse rates (0.9 episodes/patient per year, 95% CI 0.4, 1.4) without increase in steroid toxicity. Poisson regression, adjusted for occurrence of infections, showed that daily administration of prednisolone during infections independently resulted in 59% reduction in frequency of relapses (rate ratio, 0.41; 95% CI 0.3, 0.6). For every six patients receiving this intervention, one showed a reduction of relapse frequency to less than three per year. Daily administration of maintenance doses of prednisolone, during intercurrent infections, significantly reduces relapse rates and the proportion of children with frequently relapsing nephrotic syndrome.

  11. The most common problem facing by the maintenance department: A case Study between Universiti Tun Hussein Onn Malaysia (UTHM) and Universiti Teknologi Malaysia (UTM)

    NASA Astrophysics Data System (ADS)

    Norazam Yasin, Mohd; Mohamad Zin, Rosli; Halid Abdullah, Abd; Shafiq Mahmad, Muhammad; Fikri Hasmori, Muhammad

    2017-11-01

    From time to time, the maintenance works become more challenging due to construction of new building and also aging of the existing buildings. University buildings without any exception require proper maintenance services to support their function requirements and this can be considered as major responsibilities to be fulfilled by the maintenance department in the universities. Maintenance department specifically will face various kinds of problems in their operation works and thus this might influence the maintenance work operations itself. This study purposely to identify the common problem facing by the maintenance department and also to examine the current status of the maintenance department. In addition, this study would also propose any suitable approach that could be implemented to overcome the problem facing by the maintenance department. To achieve the objectives of this study, a combination of deep literature study and carrying out a survey is necessary. Literature study aimed to obtain deeper information about this study, meanwhile a survey aimed at identifying the common problem facing by the maintenance department and also to provide the information of the maintenance department’s organization. Several methods will be used in analyzing the data obtained through the survey, including Microsoft Office Excel and also using mean index formula. This study has identified three categories of problem in the maintenance department, which are management problems, human resource problem, and technical problems. Following the findings, several solutions being proposed which can be implemented as the solution to the problem facing. These suggestions have the potential to improve the maintenance department work efficiency, thus could help to increase the department productivity.

  12. Nuclear adaptor Ldb1 regulates a transcriptional program essential for the maintenance of hematopoietic stem cells

    PubMed Central

    Li, LiQi; Jothi, Raja; Cui, Kairong; Lee, Jan Y; Cohen, Tsadok; Gorivodsky, Marat; Tzchori, Itai; Zhao, Yangu; Hayes, Sandra M; Bresnick, Emery H; Zhao, Keji; Westphal, Heiner; Love, Paul E

    2013-01-01

    The nuclear adaptor Ldb1 functions as a core component of multiprotein transcription complexes that regulate differentiation in diverse cell types. In the hematopoietic lineage, Ldb1 forms a complex with the non–DNA-binding adaptor Lmo2 and the transcription factors E2A, Scl and GATA-1 (or GATA-2). Here we demonstrate a critical and continuous requirement for Ldb1 in the maintenance of both fetal and adult mouse hematopoietic stem cells (HSCs). Deletion of Ldb1 in hematopoietic progenitors resulted in the downregulation of many transcripts required for HSC maintenance. Genome-wide profiling by chromatin immunoprecipitation followed by sequencing (ChIP-Seq) identified Ldb1 complex–binding sites at highly conserved regions in the promoters of genes involved in HSC maintenance. Our results identify a central role for Ldb1 in regulating the transcriptional program responsible for the maintenance of HSCs. PMID:21186366

  13. Nuclear adaptor Ldb1 regulates a transcriptional program essential for the maintenance of hematopoietic stem cells.

    PubMed

    Li, LiQi; Jothi, Raja; Cui, Kairong; Lee, Jan Y; Cohen, Tsadok; Gorivodsky, Marat; Tzchori, Itai; Zhao, Yangu; Hayes, Sandra M; Bresnick, Emery H; Zhao, Keji; Westphal, Heiner; Love, Paul E

    2011-02-01

    The nuclear adaptor Ldb1 functions as a core component of multiprotein transcription complexes that regulate differentiation in diverse cell types. In the hematopoietic lineage, Ldb1 forms a complex with the non-DNA-binding adaptor Lmo2 and the transcription factors E2A, Scl and GATA-1 (or GATA-2). Here we demonstrate a critical and continuous requirement for Ldb1 in the maintenance of both fetal and adult mouse hematopoietic stem cells (HSCs). Deletion of Ldb1 in hematopoietic progenitors resulted in the downregulation of many transcripts required for HSC maintenance. Genome-wide profiling by chromatin immunoprecipitation followed by sequencing (ChIP-Seq) identified Ldb1 complex-binding sites at highly conserved regions in the promoters of genes involved in HSC maintenance. Our results identify a central role for Ldb1 in regulating the transcriptional program responsible for the maintenance of HSCs.

  14. 40 CFR 85.1510 - Maintenance instructions, warranties, emission labeling and fuel economy requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Maintenance instructions, warranties, emission labeling and fuel economy requirements. 85.1510 Section 85.1510 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Importation of Motor Vehicles and...

  15. 10 CFR 34.73 - Records of inspection and maintenance of radiographic exposure devices, transport and storage...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Records of inspection and maintenance of radiographic... instruments. 34.73 Section 34.73 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL RADIOGRAPHIC OPERATIONS Recordkeeping Requirements § 34.73...

  16. 41 CFR 102-33.170 - What standards must we establish or require (contractually, where applicable) for maintenance of...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What standards must we establish or require (contractually, where applicable) for maintenance of our Government aircraft? 102-33.170 Section 102-33.170 Public Contracts and Property Management Federal Property Management...

  17. 27 CFR 19.716 - Maintenance and retention of records.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Recordkeeping § 19.716 Maintenance and retention of records. (a) A proprietor of an alcohol fuel plant may keep the records required by this subpart at the alcohol fuel plant where operations or transactions occur... required records at any location other than the alcohol fuel plant where operations or transactions occur...

  18. 34 CFR 403.182 - What is the maintenance of fiscal effort requirement?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What is the maintenance of fiscal effort requirement? 403.182 Section 403.182 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION STATE VOCATIONAL AND APPLIED TECHNOLOGY...

  19. Heat-shock protein 60 is required for blastema formation and maintenance during regeneration

    PubMed Central

    Makino, Shinji; Whitehead, Geoffrey G.; Lien, Ching-Ling; Kim, Soo; Jhawar, Payal; Kono, Akane; Kawata, Yasushi; Keating, Mark T.

    2005-01-01

    Zebrafish fin regeneration requires the formation and maintenance of blastema cells. Blastema cells are not derived from stem cells but behave as such, because they are slow-cycling and are thought to provide rapidly proliferating daughter cells that drive regenerative outgrowth. The molecular basis of blastema formation is not understood. Here, we show that heat-shock protein 60 (hsp60) is required for blastema formation and maintenance. We used a chemical mutagenesis screen to identify no blastema (nbl), a zebrafish mutant with an early fin regeneration defect. Fin regeneration failed in nbl due to defective blastema formation. nbl also failed to regenerate hearts. Positional cloning and mutational analyses revealed that nbl results from a V324E missense mutation in hsp60. This mutation reduced hsp60 function in binding and refolding denatured proteins. hsp60 expression is increased during formation of blastema cells, and dysfunction leads to mitochondrial defects and apoptosis in these cells. These data indicate that hsp60 is required for the formation and maintenance of regenerating tissue. PMID:16204379

  20. 40 CFR 280.31 - Operation and maintenance of corrosion protection.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 27 2014-07-01 2014-07-01 false Operation and maintenance of corrosion... UNDERGROUND STORAGE TANKS (UST) General Operating Requirements § 280.31 Operation and maintenance of corrosion protection. All owners and operators of steel UST systems with corrosion protection must comply with the...

  1. 40 CFR 280.31 - Operation and maintenance of corrosion protection.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 28 2012-07-01 2012-07-01 false Operation and maintenance of corrosion... UNDERGROUND STORAGE TANKS (UST) General Operating Requirements § 280.31 Operation and maintenance of corrosion protection. All owners and operators of steel UST systems with corrosion protection must comply with the...

  2. 40 CFR 280.31 - Operation and maintenance of corrosion protection.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 28 2013-07-01 2013-07-01 false Operation and maintenance of corrosion... UNDERGROUND STORAGE TANKS (UST) General Operating Requirements § 280.31 Operation and maintenance of corrosion protection. All owners and operators of steel UST systems with corrosion protection must comply with the...

  3. 40 CFR 60.11 - Compliance with standards and maintenance requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... operating and maintenance procedures are being used will be based on information available to the... operating and maintenance procedures, and inspection of the source. (e)(1) For the purpose of demonstrating... Administrator, in writing, to the contrary. For the purpose of determining compliance with the opacity standard...

  4. 40 CFR 60.11 - Compliance with standards and maintenance requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... operating and maintenance procedures are being used will be based on information available to the... operating and maintenance procedures, and inspection of the source. (e)(1) For the purpose of demonstrating... Administrator, in writing, to the contrary. For the purpose of determining compliance with the opacity standard...

  5. 46 CFR 129.200 - Design, installation, and maintenance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Design, installation, and maintenance. 129.200 Section 129.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS General Requirements § 129.200 Design, installation, and maintenance. Electrical equipment on a vessel must be designed,...

  6. 46 CFR 129.200 - Design, installation, and maintenance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Design, installation, and maintenance. 129.200 Section 129.200 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS ELECTRICAL INSTALLATIONS General Requirements § 129.200 Design, installation, and maintenance. Electrical equipment on a vessel must be designed,...

  7. 10 CFR 32.3 - Maintenance of records.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Maintenance of records. 32.3 Section 32.3 Energy NUCLEAR REGULATORY COMMISSION SPECIFIC DOMESTIC LICENSES TO MANUFACTURE OR TRANSFER CERTAIN ITEMS CONTAINING BYPRODUCT MATERIAL § 32.3 Maintenance of records. Each record required by this part must be legible...

  8. 10 CFR 32.3 - Maintenance of records.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Maintenance of records. 32.3 Section 32.3 Energy NUCLEAR REGULATORY COMMISSION SPECIFIC DOMESTIC LICENSES TO MANUFACTURE OR TRANSFER CERTAIN ITEMS CONTAINING BYPRODUCT MATERIAL § 32.3 Maintenance of records. Each record required by this part must be legible...

  9. 10 CFR 11.10 - Maintenance of records.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Maintenance of records. 11.10 Section 11.10 Energy NUCLEAR REGULATORY COMMISSION CRITERIA AND PROCEDURES FOR DETERMINING ELIGIBILITY FOR ACCESS TO OR CONTROL OVER SPECIAL NUCLEAR MATERIAL General Provisions § 11.10 Maintenance of records. Each record required by this...

  10. 10 CFR 11.10 - Maintenance of records.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Maintenance of records. 11.10 Section 11.10 Energy NUCLEAR REGULATORY COMMISSION CRITERIA AND PROCEDURES FOR DETERMINING ELIGIBILITY FOR ACCESS TO OR CONTROL OVER SPECIAL NUCLEAR MATERIAL General Provisions § 11.10 Maintenance of records. Each record required by this...

  11. 48 CFR 208.7400 - Scope of subpart.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF DEFENSE ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Enterprise Software... commercial software and software maintenance, including software and software maintenance that is acquired...

  12. 48 CFR 208.7400 - Scope of subpart.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF DEFENSE ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Enterprise Software... commercial software and software maintenance, including software and software maintenance that is acquired...

  13. 48 CFR 208.7400 - Scope of subpart.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OF DEFENSE ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Enterprise Software... commercial software and software maintenance, including software and software maintenance that is acquired...

  14. 48 CFR 208.7400 - Scope of subpart.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF DEFENSE ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Enterprise Software... commercial software and software maintenance, including software and software maintenance that is acquired...

  15. Intravenous maintenance fluid therapy in children.

    PubMed

    McNab, Sarah

    2016-02-01

    Intravenous fluids are frequently used in paediatrics but have been associated with significant adverse outcomes. Understanding the composition of fluid prescribed and administering an appropriate rate is essential for safe fluid administration, along with regular monitoring. Recent evidence has shown that using an isotonic fluid with a sodium concentration similar to plasma can decrease the risk of hyponatraemia without an increase in adverse effects. This should lead to a change in guidelines: isotonic fluid should now be used as the primary maintenance intravenous fluid given to the majority of children. © 2016 The Author Journal of Paediatrics and Child Health © 2016 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

  16. Traceability of patient records usage: barriers and opportunities for improving user interface design and data management.

    PubMed

    Cruz-Correia, Ricardo; Lapão, Luís; Rodrigues, Pedro Pereira

    2011-01-01

    Although IT governance practices (like ITIL, which recommends on the use of audit logs for proper service level management) are being introduced in many Hospitals to cope with increasing levels of information quality and safety requirements, the standard maturity levels of hospital IT departments is still not enough to reach the level of frequent use of audit logs. This paper aims to address the issues related to the existence of AT in patient records, describe the Hospitals scenario and to produce recommendations. Representatives from four hospitals were interviewed regarding the use of AT in their Hospital IS. Very few AT are known to exist in these hospitals (average of 1 per hospital in an estimate of 21 existing IS). CIOs should to be much more concerned with the existence and maintenance of AT. Recommendations include server clock synchronization and using advanced log visualization tools.

  17. [Childhood obesity].

    PubMed

    Chueca, M; Azcona, C; Oyárzabal, M

    2002-01-01

    Obesity during childhood and adolescence is an increasingly frequent cause for medical consultation. The increase in the prevalence of this disease, which has been considered as an epidemic by the World Health Organisation, is worrying. Obesity is a complex disease, whose aetiology still remains to be clarified due to the numerous factors involved: environmental, genetic, life style and behavioural, neuroendocrinological and metabolic. The persistence of childhood obesity until adulthood significantly increases the risk of suffering from diabetes mellitus, cardiovascular disease, hypertension, cholecystitis and cholelithiasis. Treatment of obesity is complicated and few patients regularly attend follow up examinations. A multidisciplinary team is required to carry out a suitable treatment, composed of paediatricians, dieticians, nurses, psychologists and psychiatrists. Successful treatment of obesity resides in reducing the calorie intake in relation to energy expenditure, and at the time providing instruction in appropriate eating habits and life styles that in the long term will promote the maintenance of the ideal weight.

  18. Money-back guarantee warranty policy with preventive maintenance strategy for sensor-embedded remanufactured products

    NASA Astrophysics Data System (ADS)

    Alqahtani, Ammar Y.; Gupta, Surendra M.

    2018-01-01

    In today's global environment, technology is constantly evolving. Being able to stay up-to-date with the very latest technological advances can be extremely hard to accomplish. As a result of these changes and developments in technology, which often come unexpectedly, consumers are frequently tempted to update their devices to the very latest model. The result is that the life cycle of a product is becoming shorter and shorter than before. Manufacturers attempt to respond to consumers' concerns involving environmental issues as well as the more governmentally stringent environmental legislations by establishing facilities which include the minimization of the totality of waste relocated to landfills by recovering materials and components from returned, or End-Of-Life products and reuse them to build a remanufactured product, and/or novel components. With the rapid growth of interest in remanufactured products' market, offering warranty for remanufactured products and components is becoming a necessity for remanufacturer in order to meet customers' requirement and as a marketing mechanism. During that process, maintenance policies are of great importance in order to reduce the warranty cost on the remanufacturer. In this paper, an optimization simulation model for remanufactured items sold with one-dimensional non-renewing money-back guarantee (MBG) warranty policy is proposed from the view of remanufacturer, in which, an End-Of-Life product is subjected to upgrade action at the end of its past life and during the warranty period, preventive maintenance actions are carried out when the remaining life of the product reaches a pre-specified value so that the remanufacturer's expected profit can be maximized. Finally, a numerical example and design of experiment analysis are provided to demonstrate the proposed approach.

  19. Carving Executive Control At Its Joints: Working Memory Capacity Predicts Stimulus-Stimulus, But Not Stimulus-Response, Conflict

    PubMed Central

    Meier, Matt E.; Kane, Michael J.

    2015-01-01

    Three experiments examined the relation between working memory capacity (WMC) and two different forms of cognitive conflict: stimulus-stimulus (S-S) and stimulus-response (SR) interference. Our goal was to test whether WMC’s relation to conflict-task performance is mediated by stimulus-identification processes (captured by S-S conflict), response-selection processes (captured by S-R conflict), or both. In Experiment 1, subjects completed a single task presenting both S-S and S-R conflict trials, plus trials that combined the two conflict types. We limited ostensible goal-maintenance contributions to performance by requiring the same goal for all trial types and by presenting frequent conflict trials that reinforced the goal. WMC predicted resolution of S-S conflict as expected: Higher-WMC subjects showed reduced response time interference. Although WMC also predicted S-R interference, here, higher-WMC subjects showed increased error interference. Experiment 2A replicated these results in a version of the conflict task without combined S-S/S-R trials. Experiment 2B increased the proportion of congruent (non-conflict) trials to promote reliance on goal-maintenance processes. Here, higher-WMC subjects resolved both S-S and S-R conflict more successfully than did lower-WMC subjects. The results were consistent with Kane and Engle’s (2003) two-factor theory of cognitive control, according to which WMC predicts executive-task performance through goal-maintenance and conflict-resolution processes. However, the present results add specificity to the account by suggesting that higher-WMC subjects better resolve cognitive conflict because they more efficiently select relevant stimulus features against irrelevant, distracting ones. PMID:26120774

  20. Carving executive control at its joints: Working memory capacity predicts stimulus-stimulus, but not stimulus-response, conflict.

    PubMed

    Meier, Matt E; Kane, Michael J

    2015-11-01

    Three experiments examined the relation between working memory capacity (WMC) and 2 different forms of cognitive conflict: stimulus-stimulus (S-S) and stimulus-response (S-R) interference. Our goal was to test whether WMC's relation to conflict-task performance is mediated by stimulus-identification processes (captured by S-S conflict), response-selection processes (captured by S-R conflict), or both. In Experiment 1, subjects completed a single task presenting both S-S and S-R conflict trials, plus trials that combined the 2 conflict types. We limited ostensible goal-maintenance contributions to performance by requiring the same goal for all trial types and by presenting frequent conflict trials that reinforced the goal. WMC predicted resolution of S-S conflict as expected: Higher WMC subjects showed reduced response time interference. Although WMC also predicted S-R interference, here, higher WMC subjects showed increased error interference. Experiment 2A replicated these results in a version of the conflict task without combined S-S/S-R trials. Experiment 2B increased the proportion of congruent (nonconflict) trials to promote reliance on goal-maintenance processes. Here, higher WMC subjects resolved both S-S and S-R conflict more successfully than did lower WMC subjects. The results were consistent with Kane and Engle's (2003) 2-factor theory of cognitive control, according to which WMC predicts executive-task performance through goal-maintenance and conflict-resolution processes. However, the present results add specificity to the account by suggesting that higher WMC subjects better resolve cognitive conflict because they more efficiently select relevant stimulus features against irrelevant, distracting ones. (c) 2015 APA, all rights reserved).

  1. Beacon system based on light-emitting diode sources for runways lighting

    NASA Astrophysics Data System (ADS)

    Montes, Mario González; Vázquez, Daniel; Fernandez-Balbuena, Antonio A.; Bernabeu, Eusebio

    2014-06-01

    New aeronautical ground lighting techniques are becoming increasingly important to ensure the safety and reduce the maintenance costs of the plane's tracks. Until recently, tracks had embedded lighting systems whose sources were based on incandescent lamps. But incandescent lamps have several disadvantages: high energy consumption and frequent breakdowns that result in high maintenance costs (lamp average life-time is ˜1500 operating hours) and the lamp's technology has a lack of new lighting functions, such as signal handling and modification. To solve these problems, the industry has developed systems based on light-emitting diode (LED) technology with improved features: (1) LED lighting consumes one tenth the power, (2) it improves preventive maintenance (an LED's lifetime range is between 25,000 and 100,000 hours), and (3) LED lighting technology can be controlled remotely according to the needs of the track configuration. LEDs have been in use for more than three decades, but only recently, around 2002, have they begun to be used as visual aids, representing the greatest potential change for airport lighting since their inception in the 1920s. Currently, embedded LED systems are not being broadly used due to the specific constraints of the rules and regulations of airports (beacon dimensions, power system technology, etc.). The fundamental requirements applied to embedded lighting systems are to be hosted on a volume where the dimensions are usually critical and also to integrate all the essential components for operation. An embedded architecture that meets the lighting regulations for airport runways is presented. The present work is divided into three main tasks: development of an optical system to optimize lighting according to International Civil Aviation Organization, manufacturing prototype, and model validation.

  2. Medical equipment classification: method and decision-making support based on paraconsistent annotated logic.

    PubMed

    Oshiyama, Natália F; Bassani, Rosana A; D'Ottaviano, Itala M L; Bassani, José W M

    2012-04-01

    As technology evolves, the role of medical equipment in the healthcare system, as well as technology management, becomes more important. Although the existence of large databases containing management information is currently common, extracting useful information from them is still difficult. A useful tool for identification of frequently failing equipment, which increases maintenance cost and downtime, would be the classification according to the corrective maintenance data. Nevertheless, establishment of classes may create inconsistencies, since an item may be close to two classes by the same extent. Paraconsistent logic might help solve this problem, as it allows the existence of inconsistent (contradictory) information without trivialization. In this paper, a methodology for medical equipment classification based on the ABC analysis of corrective maintenance data is presented, and complemented with a paraconsistent annotated logic analysis, which may enable the decision maker to take into consideration alerts created by the identification of inconsistencies and indeterminacies in the classification.

  3. Maintenance therapy in colon cancer.

    PubMed

    Giuliani, F; De Vita, F; Colucci, G; Pisconti, S

    2010-11-01

    In the last decade dramatic improvements have been obtained in the treatment of metastatic colorectal cancer. Thanks to the introduction in the clinical practice of new drugs such as Irinotecan and Oxaliplatin, and modern biological drugs such as Bevacizumab and Cetuximab, the response rate, progression-free and overall survival are about 50-60%, 9-11 and 20-24 months respectively. Despite this progress, many questions remain unsolved especially those related to the optimal duration of treatment and the role of maintenance therapy. To treat until progression (or unacceptable toxicity) is the classical way but in the common clinical practice is frequent to perform an induction therapy (until the maximum response is obtained) followed by a complete stop and restart on progression, or by a maintenance without the drug/s responsible of the major cumulative toxicities. The following report focus on the role of different strategies respect to the classic "treatment until progression". Copyright © 2010 Elsevier Ltd. All rights reserved.

  4. Pesticides in surface water measured at select sites in the Sacramento River basin, California, 1996-1998

    USGS Publications Warehouse

    Domagalski, Joseph L.

    2000-01-01

    Pesticides were measured in one urban stream, one agricultural stream, one site on the Sacramento River, and one large flood control channel over a period of 18 months during 1996-1998. All sites were located within the Sacramento River Basin of California. Measurements were made on 83 pesticides or pesticide transformation products by either gas chromatography/mass spectrometry or by high performance liquid chromatography with ultraviolet light spectrometry. Some pesticides were detected frequently at the agricultural stream and downstream in the Sacramento River and at the flood control channel of the Sacramento River. These were pesticides related to rice farming (molinate, carbofuran, thiobencarb, and bentazon); herbicides used both agriculturally or for roadside maintenance (diuron, simazine, and metolachlor); or insecticides used on orchards and row corps (diazinon and chlorpyrifos). No pesticide concen-trations above enforceable water quality criteria were measured at either the agricultural site or the Sacramento River sites. In contrast to the agricul-tural site, insecticides used for household, lawn, or garden maintenance were the most frequently detected pesticides at the urban site. Diazinon, an organophosphate insecticide, exceeded recom-mended criteria for the protection of aquatic life, and the diazinon levels were frequently above known toxic levels for certain zooplankton species at the urban site. Because of the low discharge of the urban stream, pesticide concentrations were greatly diluted upon mixing with Sacramento River water.

  5. Relevance of Mood Eating Patterns to Maintenance of Weight Loss After Treatment.

    ERIC Educational Resources Information Center

    Setty, Robert M.; Hawkins, Raymond C.

    Relapses in alcoholics, smokers, and heroin users are frequently provoked by stress. Individuals often return to using addictive substances when feeling angry or frustrated as the result of negative mood states, interpersonal conflict, or social pressure. A behavioral weight-control program used to treat 140 overweight college students was…

  6. Psychological Factors in Diabetes Mellitus. A Review of the Literature with Emphasis on Adolescence.

    ERIC Educational Resources Information Center

    Greydanus, Donald E.; Hofmann, Adele D.

    1979-01-01

    Emphasis is given to the major role that emotional components play in the development and maintenance of the teenage diabetic with frequent ketoacidotic or hypoglycemic episodes. The integration of adolescent developmental issues into physician treatment plans is stressed. Journal availability: Medical Association, 535 N. Dearborn Street, Chicago,…

  7. Relationships of Self-Regard and Affective Self-Disclosure to Relationship Satisfaction in College Students.

    ERIC Educational Resources Information Center

    Vera, Elizabeth M.; Betz, Nancy E.

    The development and maintenance of romantic relationships in college students has been an increasingly frequent focus of attention among researchers interested in college student development. This study examined the role of gender in the relationships of emotional self-disclosure, self-esteem, and relationship satisfaction. Using a sample of…

  8. Collaborative Learning in Online Study Groups: An Evolutionary Game Theory Perspective

    ERIC Educational Resources Information Center

    Chiong, Raymond; Jovanovic, Jelena

    2012-01-01

    Educational benefits of online collaborative group work have been confirmed in numerous research studies. Most frequently cited advantages include the development of skills of critical thinking and problem solving as well as skills of self-reflection and co-construction of knowledge and meaning. However, the establishment and maintenance of active…

  9. An IBM Compatible Participant Data Base System for Outdoor Programs.

    ERIC Educational Resources Information Center

    Watters, Ron

    The process of maintaining mailing lists and other informational files on outdoor program participants is, plainly and simply, a pain in the neck. Mailing list maintenance is particularly difficult for programs that deal with university students, due to their frequent moves. This paper describes a new software program, the Outdoor Program Data…

  10. Net mineral requirements of dairy goats during pregnancy.

    PubMed

    Härter, C J; Lima, L D; Castagnino, D S; Silva, H O; Figueiredo, F O M; St-Pierre, N R; Resende, K T; Teixeira, I A M A

    2017-09-01

    Mineral requirements of pregnant dairy goats are still not well defined; therefore, we investigated the net Ca, P, Mg, Na and K requirements for pregnancy and for maintenance during pregnancy in two separate experiments. Experiment 1 was performed to estimate the net Ca, P, Mg, Na and K requirements in goats carrying single or twin fetuses from 50 to 140 days of pregnancy (DOP). The net mineral requirements for pregnancy were determined by measuring mineral deposition in gravid uterus and mammary gland after comparative slaughter. In total, 57 dairy goats of two breeds (Oberhasli or Saanen), in their third or fourth parturition, were randomly assigned to groups based on litter size (single or twin) and day of slaughter (50, 80, 110 and 140 DOP) in a fully factorial design. Net mineral accretion for pregnancy did not differ by goat breed. The total daily Ca, P, Mg, Na and K requirements for pregnancy were greatest in goats carrying twins (P<0.05), and the requirements increased as pregnancy progressed. Experiment 2 was performed to estimate net Ca, P, Mg, Na and K requirements for dairy goat maintenance during pregnancy. In total, 58 dairy goats (Oberhasli and Saanen) carrying twin fetuses were assigned to groups based on slaughter day (80, 110 and 140 DOP) and feed restriction (ad libitum, 20% and 40% feed restriction) in a randomized block design. The net Ca, P and Mg requirements for maintenance did not vary by breed or over the course of pregnancy. The daily net requirements of Ca, P and Mg for maintenance were 60.4, 31.1 and 2.42 mg/kg live BW (LBW), respectively. The daily net Na requirement for maintenance was greater in Saanen goats (11.8 mg/kg LBW) than in Oberhasli goats (8.96 mg/kg LBW; P<0.05). Daily net K requirements increased as pregnancy progressed from 8.73 to 15.4 mg/kg LBW (P<0.01). The findings of this study will guide design of diets with adequate mineral content for pregnant goats throughout their pregnancy.

  11. Multirate state and parameter estimation in an antibiotic fermentation with delayed measurements.

    PubMed

    Gudi, R D; Shah, S L; Gray, M R

    1994-12-01

    This article discusses issues related to estimation and monitoring of fermentation processes that exhibit endogenous metabolism and time-varying maintenance activity. Such culture-related activities hamper the use of traditional, software sensor-based algorithms, such as the extended kalman filter (EKF). In the approach presented here, the individual effects of the endogenous decay and the true maintenance processes have been lumped to represent a modified maintenance coefficient, m(c). Model equations that relate measurable process outputs, such as the carbon dioxide evolution rate (CER) and biomass, to the observable process parameters (such as net specific growth rate and the modified maintenance coefficient) are proposed. These model equations are used in an estimator that can formally accommodate delayed, infrequent measurements of the culture states (such as the biomass) as well as frequent, culture-related secondary measurements (such as the CER). The resulting multirate software sensor-based estimation strategy is used to monitor biomass profiles as well as profiles of critical fermentation parameters, such as the specific growth for a fed-batch fermentation of Streptomyces clavuligerus.

  12. Centralized vs. decentralized thermal IR inspection policy: experience from a major Brazilian electric power company

    NASA Astrophysics Data System (ADS)

    dos Santos, Laerte; da Costa Bortoni, Edson; Barbosa, Luiz C.; Araujo, Reyler A.

    2005-03-01

    Furnas Centrais Elétricas S.A is one of the greatest companies of the Brazilian electric power sector and a pioneer in using infrared thermography. In the early 70s, the maintenance policy used was a centralized approach, with only one inspection team to cover all the company"s facilities. In the early 90s, FURNAS decided to decentralize the thermography inspections creating several inspection teams. This new maintenance policy presented several advantages when compared to the previous one. However the credibility of the results obtained with the thermal inspection was frequently being questioned, in part due to the lack of a detailed planning to carry out the transition from the centralized inspection to the decentralized one. In some areas of the company it was suggested the inactivation of the thermography. This paper presents the experience of FURNAS with these different maintenance policies and details the procedures which have been taken that nowadays the infrared thermal inspection has become one of the most important techniques of predictive maintenance in the company.

  13. Fluid overload in the ICU: evaluation and management.

    PubMed

    Claure-Del Granado, Rolando; Mehta, Ravindra L

    2016-08-02

    Fluid overload is frequently found in acute kidney injury patients in critical care units. Recent studies have shown the relationship of fluid overload with adverse outcomes; hence, manage and optimization of fluid balance becomes a central component of the management of critically ill patients. In critically ill patients, in order to restore cardiac output, systemic blood pressure and renal perfusion an adequate fluid resuscitation is essential. Achieving an appropriate level of volume management requires knowledge of the underlying pathophysiology, evaluation of volume status, and selection of appropriate solution for volume repletion, and maintenance and modulation of the tissue perfusion. Numerous recent studies have established a correlation between fluid overload and mortality in critically ill patients. Fluid overload recognition and assessment requires an accurate documentation of intakes and outputs; yet, there is a wide difference in how it is evaluated, reviewed and utilized. Accurate volume status evaluation is essential for appropriate therapy since errors of volume evaluation can result in either in lack of essential treatment or unnecessary fluid administration, and both scenarios are associated with increased mortality. There are several methods to evaluate fluid status; however, most of the tests currently used are fairly inaccurate. Diuretics, especially loop diuretics, remain a valid therapeutic alternative. Fluid overload refractory to medical therapy requires the application of extracorporeal therapies. In critically ill patients, fluid overload is related to increased mortality and also lead to several complications like pulmonary edema, cardiac failure, delayed wound healing, tissue breakdown, and impaired bowel function. Therefore, the evaluation of volume status is crucial in the early management of critically ill patients. Diuretics are frequently used as an initial therapy; however, due to their limited effectiveness the use of continuous renal replacement techniques are often required for fluid overload treatment. Successful fluid overload treatment depends on precise assessment of individual volume status, understanding the principles of fluid management with ultrafiltration, and clear treatment goals.

  14. Maintenance as a safety issue.

    PubMed

    White, Jim

    2008-11-01

    Because safety is related to electrical power systems maintenance, it seems reasonable to assume there could be legal issues if maintenance is not performed. OSHA has not yet taken the stand that not performing maintenance as required by the manufacturer, NFPA 70B, or ANSI/NETA MTS-07 constitutes a willful violation. OSHA defines a willful citation as one where: "the employer knowingly commits with plain indifference to the law. The employer either knows that what he or she is doing constitutes a violation, or is aware that a hazardous condition existed and made no reasonable effort to eliminate it". However, NFPA 70E 2009 requires this maintenance, and OSHA has stated on its Web site that NFPA 70E is "a guide for meeting the requirements of the OSHA electrical regulations". In addition, federal courts have found that NFPA 70E is "standard industry practice." Once a company receives and accepts a willful citation, especially if received as the result of an accident investigation, its worker's compensation protection no longer shields it. One definition given by a trial attorney for a willful citation was that it is equal to negligent behavior. Be smart: Maintain that equipment and save yourself major problems, including unscheduled shutdowns and possible litigation.

  15. Treatment patterns of adjuvant interferon-α2b for high-risk melanoma: a retrospective study of the Grupo Español Multidisciplinar de Melanoma – Prima study

    PubMed Central

    Soriano, Virtudes; Malvehy, Josep; Berrocal, Alfonso; Martínez de Prado, Purificación; Quindós, María; Soria, Ainara; Márquez-Rodas, Iván; Palacio, Isabel; Cerezuela, Pablo; López-Vivanco, Guillermo; Alonso, Lorenzo; Samaniego, Elia; Ballesteros, Ana; Puértolas, Teresa; Díaz-Beveridge, Rodrigo; de la Cruz-Merino, Luis; López Castro, Rafael; López López, Rafael; Stevinson, Kendall; del Barrio, Patricia; Tornamira, Maria V.; Guillém, Vicente; Martín-Algarra, Salvador

    2016-01-01

    Adjuvant interferon-α2b (IFN-α2b) has been studied extensively in clinical trials, but there have been few studies of real-world use. The aim of this study is to describe the IFN-α2b real-world patterns in patients with high-risk melanoma in Spain. This was a retrospective and multicentre chart review study of an unselected cohort of patients with melanoma at high risk for relapse (stage IIB/IIC/III) treated with IFN-α2b. Patterns were assessed in terms of dose and compliance to planned treatment. A survival analysis was carried out for the full population and according to Kirkwood scheme compliance and the presence of ulceration. Of 327 patients treated with IFN-α2b, 318 received a high-dose regimen following the standard Kirkwood scheme; thus, patterns are described for this regimen. A total of 121 (38%) and 88 (28%) patients had at least one dose reduction during the induction and maintenance phases, respectively. Dose delay was required in fewer than 10% of patients. A total of 78, 40 and 38% of the patients completed the induction phase, maintenance phase and completed treatment, respectively. The median progression-free and overall survival for the full population were 3.2 and 10.5 years, respectively. There were no differences in progression-free survival and overall survival according to Kirkwood scheme compliance and the presence of ulceration. The most frequent adverse events were neutropenia (31%) and fatigue (30%). High-dose IFN-α2b is the most frequently used regimen in Spain as an adjuvant systemic treatment for high-risk melanoma. Despite poor compliance, in this retrospective study, IFN-α2b treatment provided a benefit consistent with that described previously. PMID:26958991

  16. Treatment patterns of adjuvant interferon-α2b for high-risk melanoma: a retrospective study of the Grupo Español Multidisciplinar de Melanoma - Prima study.

    PubMed

    Espinosa, Enrique; Soriano, Virtudes; Malvehy, Josep; Berrocal, Alfonso; Martínez de Prado, Purificación; Quindós, María; Soria, Ainara; Márquez-Rodas, Iván; Palacio, Isabel; Cerezuela, Pablo; López-Vivanco, Guillermo; Alonso, Lorenzo; Samaniego, Elia; Ballesteros, Ana; Puértolas, Teresa; Díaz-Beveridge, Rodrigo; de la Cruz-Merino, Luis; López Castro, Rafael; López López, Rafael; Stevinson, Kendall; Del Barrio, Patricia; Tornamira, Maria V; Guillém, Vicente; Martín-Algarra, Salvador

    2016-06-01

    Adjuvant interferon-α2b (IFN-α2b) has been studied extensively in clinical trials, but there have been few studies of real-world use. The aim of this study is to describe the IFN-α2b real-world patterns in patients with high-risk melanoma in Spain. This was a retrospective and multicentre chart review study of an unselected cohort of patients with melanoma at high risk for relapse (stage IIB/IIC/III) treated with IFN-α2b. Patterns were assessed in terms of dose and compliance to planned treatment. A survival analysis was carried out for the full population and according to Kirkwood scheme compliance and the presence of ulceration. Of 327 patients treated with IFN-α2b, 318 received a high-dose regimen following the standard Kirkwood scheme; thus, patterns are described for this regimen. A total of 121 (38%) and 88 (28%) patients had at least one dose reduction during the induction and maintenance phases, respectively. Dose delay was required in fewer than 10% of patients. A total of 78, 40 and 38% of the patients completed the induction phase, maintenance phase and completed treatment, respectively. The median progression-free and overall survival for the full population were 3.2 and 10.5 years, respectively. There were no differences in progression-free survival and overall survival according to Kirkwood scheme compliance and the presence of ulceration. The most frequent adverse events were neutropenia (31%) and fatigue (30%). High-dose IFN-α2b is the most frequently used regimen in Spain as an adjuvant systemic treatment for high-risk melanoma. Despite poor compliance, in this retrospective study, IFN-α2b treatment provided a benefit consistent with that described previously.

  17. The Literacy Requirements of an Industrial Maintenance Mechanic on the Job and in a Vocational Training Program.

    ERIC Educational Resources Information Center

    Moe, Alden J.; And Others

    As part of a project that identified the specific literacy skills required in ten occupations, this report provides two levels of instructional information about industrial maintenance mechanics. Factual data are presented in Parts I and II for use in decision making by program developers, administrators, teachers, and counselors. These sections…

  18. 40 CFR 63.7335 - How do I demonstrate continuous compliance with the operation and maintenance requirements that...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Standards for Hazardous Air Pollutants for Coke Ovens: Pushing, Quenching, and Battery Stacks Continuous... maintenance requirements that apply to me? (a) For each by-product coke oven battery, you must demonstrate... each coke oven battery with a capture system or control device applied to pushing emissions, you must...

  19. 40 CFR 63.7335 - How do I demonstrate continuous compliance with the operation and maintenance requirements that...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Standards for Hazardous Air Pollutants for Coke Ovens: Pushing, Quenching, and Battery Stacks Continuous... maintenance requirements that apply to me? (a) For each by-product coke oven battery, you must demonstrate... each coke oven battery with a capture system or control device applied to pushing emissions, you must...

  20. 40 CFR 63.7335 - How do I demonstrate continuous compliance with the operation and maintenance requirements that...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Standards for Hazardous Air Pollutants for Coke Ovens: Pushing, Quenching, and Battery Stacks Continuous... maintenance requirements that apply to me? (a) For each by-product coke oven battery, you must demonstrate... each coke oven battery with a capture system or control device applied to pushing emissions, you must...

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