Measurement of whole tire profile

NASA Astrophysics Data System (ADS)

Yang, Yongyue; Jiao, Wenguang

2010-08-01

In this paper, a precision measuring device is developed for obtaining characteristic curve of tire profile and its geometric parameters. It consists of a laser displacement measurement unit, a closed-loop precision two-dimensional coordinate table, a step motor control system and a fast data acquisition and analysis system. Based on the laser trigonometry, a data map of tire profile and coordinate values of all points can be obtained through corresponding data transformation. This device has a compact structure, a convenient control, a simple hardware circuit design and a high measurement precision. Experimental results indicate that measurement precision can meet the customer accuracy requirement of +/-0.02 mm.

Cluster: A fleet of four spacecraft to study plasma structures in three dimensions

NASA Technical Reports Server (NTRS)

Schmidt, R.; Goldstein, M. L.

1988-01-01

The four Cluster spacecraft are spin stabilized spacecraft which are designed and built under stringent requirements as far as electromagnetic cleanliness is concerned. Conductive surfaces and low electromagnetic background noise are mandatory for accurate electric field and cold plasma measurements. The mission is implemented in collaboration between ESA and NASA. A Russian mission will be closely coordinated with Cluster.

A relativistic gravity train

NASA Astrophysics Data System (ADS)

Parker, Edward

2017-08-01

A nonrelativistic particle released from rest at the edge of a ball of uniform charge density or mass density oscillates with simple harmonic motion. We consider the relativistic generalizations of these situations where the particle can attain speeds arbitrarily close to the speed of light; generalizing the electrostatic and gravitational cases requires special and general relativity, respectively. We find exact closed-form relations between the position, proper time, and coordinate time in both cases, and find that they are no longer harmonic, with oscillation periods that depend on the amplitude. In the highly relativistic limit of both cases, the particle spends almost all of its proper time near the turning points, but almost all of the coordinate time moving through the bulk of the ball. Buchdahl's theorem imposes nontrivial constraints on the general-relativistic case, as a ball of given density can only attain a finite maximum radius before collapsing into a black hole. This article is intended to be pedagogical, and should be accessible to those who have taken an undergraduate course in general relativity.

The coordination patterns observed when two hands reach-to-grasp separate objects.

PubMed

Bingham, Geoffrey P; Hughes, Kirstie; Mon-Williams, Mark

2008-01-01

What determines coordination patterns when both hands reach to grasp separate objects at the same time? It is known that synchronous timing is preferred as the most stable mode of bimanual coordination. Nonetheless, normal unimanual prehension behaviour predicts asynchrony when the two hands reach towards unequal targets, with synchrony restricted to targets equal in size and distance. Additionally, sufficiently separated targets require sequential looking. Does synchrony occur in all cases because it is preferred in bimanual coordination or does asynchrony occur because of unimanual task constraints and the need for sequential looking? We investigated coordinative timing when participants (n = 8) moved their right (preferred) hand to the same object at a fixed distance but the left hand to objects of different width (3, 5, and 7 cm) and grip surface size (1, 2, and 3 cm) placed at different distances (20, 30, and 40 cm) over 270 randomised trials. The hand movements consisted of two components: (1) an initial component (IC) during which the hand reached towards the target while forming an appropriate grip aperture, stopping at (but not touching) the object; (2) a completion component (CC) during which the finger and thumb closed on the target. The two limbs started the IC together but did not interact until the deceleration phase when evidence of synchronisation began to appear. Nonetheless, asynchronous timing was present at the end of the IC and preserved through the CC even with equidistant targets. Thus, there was synchrony but requirements for visual information ultimately yielded asynchronous coordinative timing.

Cost of close the gap for vision of Indigenous Australians: On estimating the extra resources required.

PubMed

Hsueh, Ya-seng Arthur; Brando, Alex; Dunt, David; Anjou, Mitchell D; Boudville, Andrea; Taylor, Hugh

2013-12-01

To estimate the costs of the extra resources required to close the gap of vision between Indigenous and non-Indigenous Australians. Constructing comprehensive eye care pathways for Indigenous Australians with their related probabilities, to capture full eye care usage compared with current usage rate for cataract surgery, refractive error and diabetic retinopathy using the best available data. Urban and remote regions of Australia. The provision of eye care for cataract surgery, refractive error and diabetic retinopathy. Estimated cost needed for full access, estimated current spending and estimated extra cost required to close the gaps of cataract surgery, refractive error and diabetic retinopathy for Indigenous Australians. Total cost needed for full coverage of all three major eye conditions is $45.5 million per year in 2011 Australian dollars. Current annual spending is $17.4 million. Additional yearly cost required to close the gap of vision is $28 million. This includes extra-capped funds of $3 million from the Commonwealth Government and $2 million from the State and Territory Governments. Additional coordination costs per year are $13.3 million. Although available data are limited, this study has produced the first estimates that are indicative of the need for planning and provide equity in eye care. © 2013 The Authors. Australian Journal of Rural Health © National Rural Health Alliance Inc.

Multivariate Relationships among Morphology, Fitness and Motor Coordination in Prepubertal Girls

PubMed Central

Luz, Leonardo G. O.; Coelho-e-Silva, Manuel J.; Duarte, João P.; Valente-dos-Santos, João; Machado-Rodrigues, Aristides; Seabra, André; Carmo, Bruno C. M.; Vaeyens, Roel; Philippaerts, Renaat M.; Cumming, Sean P.; Malina, Robert M.

2018-01-01

Motor coordination and physical fitness are multidimensional concepts which cannot be reduced to a single variable. This study evaluated multivariate relationships among morphology, physical fitness and motor coordination in 74 pre-pubertal girls 8.0-8.9 years of age. Data included body dimensions, eight fitness items and four motor coordination tasks (KTK battery). Maturity status was estimated as percentage of predicted mature stature attained at the time of observation. Canonical correlation analysis was used to examine the relationships between multivariate domains. Significant pairs of linear functions between indicators of morphology and fitness (rc = 0.778, Wilks’ Lambda = 0.175), and between fitness and motor coordination (rc = 0.765, Wilks’ Lambda = 0.289) were identified. Girls who were lighter and had a lower waist-to-stature ratio and % fat mass attained better scores in the endurance run, sit-ups and standing long jump tests, but poorer performances in hand grip strength and 2-kg ball throw. Better fitness test scores were also associated with better motor coordination scores. Relationships between body size and estimated fatness with motor fitness suggested an inverse relationship that was particularly evident in performance items that required the displacement of the body through space, while motor coordination was more closely related with fitness than with somatic variables. Key points Morphology and motor coordination were not substantially related in this sample of 8-year-old girls suggesting that motor coordination was independent of variation in morphology. Sit-ups (abdominal strength and endurance), the 10x5-m shuttle run (agility) and the 20-m aerobic endurance tests were the main contributors to the significant canonical correlation between fitness and motor coordination. By inference, development of these components of fitness is important during the primary school years. Relationships between estimated maturity status based on percentage of predicted mature height and fitness and coordination were negligible, with the exception of a moderate and inverse association with aerobic endurance. Nevertheless, within the single chronological age group, girls who were advanced in maturity status tended to taller and heavier and performed better in tests which did not require displacement of the body through space. PMID:29769820

The Global Fund's paradigm of oversight, monitoring, and results in Mozambique.

PubMed

Warren, Ashley; Cordon, Roberto; Told, Michaela; de Savigny, Don; Kickbusch, Ilona; Tanner, Marcel

2017-12-12

The Global Fund is one of the largest actors in global health. In 2015 the Global Fund was credited with disbursing close to 10 % of all development assistance for health. In 2011 it began a reform process in response to internal reviews following allegations of recipients' misuse of funds. Reforms have focused on grant application processes thus far while the core structures and paradigm have remained intact. We report results of discussions with key stakeholders on the Global Fund, its paradigm of oversight, monitoring, and results in Mozambique. We conducted 38 semi-structured in-depth interviews in Maputo, Mozambique and members of the Global Fund Board and Secretariat in Switzerland. In-country stakeholders were representatives from Global Fund country structures (eg. Principle Recipient), the Ministry of Health, health or development attachés bilateral and multilateral agencies, consultants, and the NGO coordinating body. Thematic coding revealed concerns about the combination of weak country oversight with stringent and cumbersome requirements for monitoring and evaluation linked to performance-based financing. Analysis revealed that despite the changes associated with the New Funding Model, respondents in both Maputo and Geneva firmly believe challenges remain in Global Fund's structure and paradigm. The lack of a country office has many negative downstream effects including reliance on in-country partners and ineffective coordination. Due to weak managerial and absorptive capacity, more oversight is required than is afforded by country team visits. In-country partners provide much needed support for Global Fund recipients, but roles, responsibilities, and accountability must be clearly defined for a successful long-term partnership. Furthermore, decision-makers in Geneva recognize in-country coordination as vital to successful implementation, and partners welcome increased Global Fund engagement. To date, there are no institutional requirements for formalized coordination, and the Global Fund has no consistent representation in Mozambique's in-country coordination groups. The Global Fund should adapt grant implementation and monitoring procedures to the specific local realities that would be illuminated by more formalized coordination.

A coordinated control strategy for insulin and glucagon delivery in type 1 diabetes.

PubMed

Herrero, Pau; Bondia, Jorge; Oliver, Nick; Georgiou, Pantelis

2017-10-01

Type 1 diabetes is an autoimmune condition characterised by a pancreatic insulin secretion deficit, resulting in high blood glucose concentrations, which can lead to micro- and macrovascular complications. Type 1 diabetes also leads to impaired glucagon production by the pancreatic α-cells, which acts as a counter-regulatory hormone to insulin. A closed-loop system for automatic insulin and glucagon delivery, also referred to as an artificial pancreas, has the potential to reduce the self-management burden of type 1 diabetes and reduce the risk of hypo- and hyperglycemia. To date, bihormonal closed-loop systems for glucagon and insulin delivery have been based on two independent controllers. However, in physiology, the secretion of insulin and glucagon in the body is closely interconnected by paracrine and endocrine associations. In this work, we present a novel biologically-inspired glucose control strategy that accounts for such coordination. An in silico study using an FDA-accepted type 1 simulator was performed to evaluate the proposed coordinated control strategy compared to its non-coordinated counterpart, as well as an insulin-only version of the controller. The proposed coordinated strategy achieves a reduction of hyperglycemia without increasing hypoglycemia, when compared to its non-coordinated counterpart.

An experiment to enable commercial mobile satellite service

NASA Technical Reports Server (NTRS)

Lovell, R. R.; Knouse, G. H.; Weber, W. J.

1982-01-01

A Mobile Satellite Experiment (MSAT-X) is described, based on a planned cooperative U.S./Canadian program. The experiment would establish network architecture, develop system and ground-segment technology, and define the technical characteristics needed to help structure the regulatory/institutional framework needed to enable a first-generation commercial satellite service. A satellite of this type would augment terrestrial systems, both cellular and noncellular, in the thin-route/rural areas of the country where service is either unavailable or inadequate. Applications range from wide-area radio/dispatch (e.g., oil exploration and interstate trucking) to extension of the public mobile telephone service. Market estimates are provided and experiment objectives and requirements are delineated. The requirements are being developed in close coordination with the Department of Communications (DOC) of Canada and with industry and potential-user organizations. The paper closes with a development plan and milestone chart.

Close range fault tolerant noncontacting position sensor

DOEpatents

Bingham, D.N.; Anderson, A.A.

1996-02-20

A method and system are disclosed for locating the three dimensional coordinates of a moving or stationary object in real time. The three dimensional coordinates of an object in half space or full space are determined based upon the time of arrival or phase of the wave front measured by a plurality of receiver elements and an established vector magnitudes proportional to the measured time of arrival or phase at each receiver element. The coordinates of the object are calculated by solving a matrix equation or a set of closed form algebraic equations. 3 figs.

7 CFR 1927.56 - Scheduling loan closing.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false Scheduling loan closing. 1927.56 Section 1927.56... REGULATIONS TITLE CLEARANCE AND LOAN CLOSING Real Estate Title Clearance and Loan Closing § 1927.56 Scheduling loan closing. The agency, in coordination with the closing agent, will arrange a loan closing and send...

Common knowledge: Now you have it, now you don`t?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fagin, R.; Halpern, J.Y.; Moses, Y.

The notion of common knowledge, where everyone knows, everyone knows that everyone knows, etc., has proven to be fundamental in various disciplines, including Philosophy, Artificial Intelligence, Economics, and Psychology. This key notion was first studied by the philosopher David Lewis in the context of conventions. Lewis pointed out that in order for something to be a convention, it must in fact be common knowledge among the members of a group. (For example, the convention that green means {open_quotes}go{close_quotes} and red means {open_quotes}stop{close_quotes} is presumably common knowledge among the drivers in our society.) Common knowledge also arises in discourse understanding. Supposemore » Ann asks Bob {open_quotes}What did you think of the movie?{close_quotes} referring to a showing of Monkey Business they have just seen. Not only must Ann and Bob both know that {open_quotes}the movie{close_quotes} refers to Monkey Business, but Ann must know that Bob knows, Bob must know that Ann knows that Bob knows, and so on. In fact, by a closer analysis of this situation, it can be shown that there must be common knowledge of what movie is meant in order for Bob to answer the question appropriately. Finally, common knowledge also turns out to be a prerequisite for agreement and coordinated action in distributed systems. This is precisely what makes it such a crucial notion in the analysis of interacting groups of agents. On the other hand, in practical settings common knowledge is impossible to achieve. This puts us in a somewhat paradoxical situation, in that we claim both that common knowledge is a prerequisite for agreement and coordinated action and that it cannot be attained. We discuss two answers to this paradox: Modeling the world with a coarser granularity, and relaxing the requirements for coordination.« less

Strategy for Improved Representation of Magnetospheric Electric Potential Structure on a Polar-Capped Ionosphere

NASA Astrophysics Data System (ADS)

Schulz, M.

2016-12-01

In some simple models of magnetospheric electrodynamics [e.g., Volland, Ann. Géophys., 31, 159-173, 1975], the normal component of the convection electric field is discontinuous across the boundary between closed and open magnetic field lines, and this discontinuity facilitates the formation of auroral arcs there. The requisite discontinuity in E is achieved by making the scalar potential proportional to a positive power (typically 1 or 2) of L on closed field lines and to a negative power (typically -1/2) of L on open (i.e., polar-cap) field lines. This suggests that it may be advantageous to construct more realistic (and thus more complicated) empirical magnetospheric and ionospheric electric-field models from superpositions of mutually orthogonal (or not) vector basis functions having this same analytical property (i.e., discontinuity at L = L*, the boundary surface between closed and open magnetic field lines). The present work offers a few examples of such constructions. A major challenge in this project has been to devise a coordinate system that simplifies the required analytical expansions of electric scalar potentials and accommodates the anti-sunward offset of each polar-cap boundary's centroid with respect to the corresponding magnetic pole. For circular northern and southern polar caps containing equal amounts of magnetic flux, one can imagine a geometrical construction of nested circular (but non-concentric) contours of constant quasi-latitude whose centers converge toward the magnetic poles as the contours themselves approach the magnetic equator. For more general polar-cap shapes and (in any case) to assure mutual orthogonality of respective coordinate surfaces on a spherical ionosphere, a formulation based on harmonic coordinates (expanded from eigen-solutions of the two-dimensional Laplace equation) may be preferable.

Towards a strategic alignment of public health and primary care practices at local levels - the case of severe and enduring mental illness.

PubMed

Banarsee, Ricky; Kelly, Cornelius; El-Osta, Austen; Thomas, Paul; Brophy, Chris

2018-03-01

The rapidly increasing number of people who have long-term conditions requires a system of coordinated support for self-care throughout the NHS. A system to support self-care needs to be aligned to systems that support shared-care and community development, making it easier for the multidisciplinary teams who provide care to also help patients and populations to help themselves. Public health practitioners need to work closely with clinicians to achieve this. The best place to coordinate this partnership is a community-based coordinating hub, or local health community - a geographic area of about 50,000 population where different contributions to self-care can be aligned. A shared vision for both health and disease management is needed to ensure consistent messaging by all. A three tier system of shared care can help to combine vertical and horizontal integration. This paper uses severe and enduring mental illness as an exemplar to anticipate the design of such a system.

Applications of Differential Operators in Geodetic Coordinates

NASA Astrophysics Data System (ADS)

Hallam, K. A. T.; Oliveira, V. C., Jr.

2016-12-01

The definition of coordinate systems and frames is an essential step to even start a problem in physical geodesy and geophysics. The commonly used coordinate systems when dealing with problems on (or close to) the surface of the Earth are the geocentric Cartesian coordinates, geocentric spherical coordinates and geodetic coordinates. Transformations between Cartesian and spherical coordinates are widely known and used for several problems. More complex, but not less important, are the transformations between Cartesian and geodetic coordinates. Although most of them utilize an ellipsoidal frame in which the three coordinates are geodetic longitude (λ), geodetic latitude (φ) and the scale factor (u), the latter being a combination of X and Y, not the geometric height (h), the data sets measured on (or close to) the surface of the Earth are given in geodetic coordinates which are usually transformed into Cartesian or spherical coordinates for mathematical developments. It would be useful, however, to preclude coordinate transformations for the subsequent operations. Thus, we derived expressions for the gradient and Laplacian operators in geodetic coordinates in order to make further use on mathematical developments. Results obtained analitically and from numerical simulations validate our expressions. We applied our operators to derive the gravitational field produced by a point mass and used it for representing the regional gravity field in geodetic coordinates. The results obtained with the numerical simulations show that our approach is potentially useful in solving a wide range of problems in physical geodesy and geophysics.

Use of DoD Architectural Framework in Support of JFIIT Assessments

DTIC Science & Technology

2007-06-12

ACCA ASCA Div FSCA BCT/Regt FSCA Bn FSCA TACP TACP TACP JFO/Observer Friendly Forces Air RCA OV-1 for TA 3.2.2 Conduct Close Air Support OV-1 for TA...3.2.2 Conduct Close Air Support Ground RCA ISR FSCA/ ACCA CAS Aircraft FAC(A) Indirect Surface Fires Hostile Targets WOC TACP GLO Legend ACCA Air...FAC(A)/CAS Aircrew A3.1.4 Control CAS A3.2.1 Coordinate with WOC/ ACCA /ASCA/ACA A3.2.2 Coordinate with JTAC A3.2.3 Provide CAS A3.3.1 Coordinate with

Stopping Illicit Procurement: Lessons from Global Finance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hund, Gretchen; Kurzrok, Andrew J.

Government regulators and the financial sector cooperate to combat money laundering and terrorist financing. This information-sharing relationship is built upon a strong legislative foundation and effective operational procedures. As with money-laundering and terrorist financing, halting the illicit procurement of dual-use commodities requires close coordination between government and industry. However, many of the legal and operational features present in financial threat cooperation do not exist in the export control realm. This article analyzes the applicability of financial industry cooperative measures to nonproliferation.

Empirical Evaluation of a Model of Team Collaboration Using Selected Transcripts from September 11, 2001

DTIC Science & Technology

2009-06-01

close coordination between the FAA and NORAD is required in order to maintain safety of the U.S. airspace. In order to interpret how the FAA and...386 Sergeant Bianchi: Hi, Sergeant Lucas calling from Lotus . MISC MISC MISC 387 Sergeant Bianchi: Yeah. MISC MISC MISC 388 Sergeant Lucas...TIE These guys have been sitting here and messing with this stuff. TIE US TIE You need some kind of food . TIE MISC MISC Sir

Proposal for Ground Safety Review Coordination at ISS Launch Sites

NASA Technical Reports Server (NTRS)

Kirkpatrick, Paul D.

2010-01-01

As the transportation of ISS payloads and cargo shifts from KSC to other launch sites, close coordination of ground safety review processes would be of benefit to all parties. The benefit would have the launch sites receiving consistent data that would require less effort to review while still meeting their needs. Until recently, ground safety focus for the ISS program has been almost exclusively for prelaunch processing at KSC/post-landing processing at KSC/DFRC Each launch site, used by the ISS Program, has a ground safety review process. Ground safety viewed as local prerogative. Up till now, ground processing has consisted of low risk/low hazard items; but this will not always be the case. Recent coordination issues associated with the ground safety review of ORU's to be processed at Tanegashima for HTV-2, illustrate that IP ground safety review processes are not well understood by the ISS community at large. Confusion for data providers (US only?). Lack of internal review process for data being submitted to launch sites can lead to inconsistent submittals. NCRs/HRs. Majority of IP ground safety requirements are based upon old KHB 1700.7 (now KNPR 8715.3, Chapter 20). Proposals include: Establish a ground safety working group as part of the MS&MAP. Search for efficiencies in requirements and data submittal processes. Document processes in NSTS 13830/SSP 30599. Each launch site report out its payload ground safety status at the F2F (Monthly's as required). Completions/due dates/NCRs/issues/changes. Establish internal processes for review of ground safety submittals.

The MADS Box Genes ABS, SHP1, and SHP2 Are Essential for the Coordination of Cell Divisions in Ovule and Seed Coat Development and for Endosperm Formation in Arabidopsis thaliana

PubMed Central

Tekleyohans, Dawit G.; Wittkop, Benjamin; Snowdon, Rod J.

2016-01-01

Seed formation is a pivotal process in plant reproduction and dispersal. It begins with megagametophyte development in the ovule, followed by fertilization and subsequently coordinated development of embryo, endosperm, and maternal seed coat. Two closely related MADS-box genes, SHATTERPROOF 1 and 2 (SHP1 and SHP2) are involved in specifying ovule integument identity in Arabidopsis thaliana. The MADS box gene ARABIDOPSIS BSISTER (ABS or TT16) is required, together with SEEDSTICK (STK) for the formation of endothelium, part of the seed coat and innermost tissue layer formed by the maternal plant. Little is known about the genetic interaction of SHP1 and SHP2 with ABS and the coordination of endosperm and seed coat development. In this work, mutant and expression analysis shed light on this aspect of concerted development. Triple tt16 shp1 shp2 mutants produce malformed seedlings, seed coat formation defects, fewer seeds, and mucilage reduction. While shp1 shp2 mutants fail to coordinate the timely development of ovules, tt16 mutants show less peripheral endosperm after fertilization. Failure in coordinated division of the innermost integument layer in early ovule stages leads to inner seed coat defects in tt16 and tt16 shp1 shp2 triple mutant seeds. An antagonistic action of ABS and SHP1/SHP2 is observed in inner seed coat layer formation. Expression analysis also indicates that ABS represses SHP1, SHP2, and FRUITFUL expression. Our work shows that the evolutionary conserved Bsister genes are required not only for endothelium but also for endosperm development and genetically interact with SHP1 and SHP2 in a partially antagonistic manner. PMID:27776173

Wounding coordinately induces cell wall protein, cell cycle and pectin methyl esterase genes involved in tuber closing layer and wound periderm development.

PubMed

Neubauer, Jonathan D; Lulai, Edward C; Thompson, Asunta L; Suttle, Jeffrey C; Bolton, Melvin D

2012-04-15

Little is known about the coordinate induction of genes that may be involved in agriculturally important wound-healing events. In this study, wound-healing events were determined together with wound-induced expression profiles of selected cell cycle, cell wall protein, and pectin methyl esterase genes using two diverse potato genotypes and two harvests (NDTX4271-5R and Russet Burbank tubers; 2008 and 2009 harvests). By 5 d after wounding, the closing layer and a nascent phellogen had formed. Phellogen cell divisions generated phellem layers until cessation of cell division at 28 d after wounding for both genotypes and harvests. Cell cycle genes encoding epidermal growth factor binding protein (StEBP), cyclin-dependent kinase B (StCDKB) and cyclin-dependent kinase regulatory subunit (StCKS1At) were induced by 1 d after wounding; these expressions coordinated with related phellogen formation and the induction and cessation of phellem cell formation. Genes encoding the structural cell wall proteins extensin (StExt1) and extensin-like (StExtlk) were dramatically up-regulated by 1-5 d after wounding, suggesting involvement with closing layer and later phellem cell layer formation. Wounding up-regulated pectin methyl esterase genes (StPME and StPrePME); StPME expression increased during closing layer and phellem cell formation, whereas maximum expression of StPrePME occurred at 5-14 d after wounding, implicating involvement in later modifications for closing layer and phellem cell formation. The coordinate induction and expression profile of StTLRP, a gene encoding a cell wall strengthening "tyrosine-and lysine-rich protein," suggested a role in the formation of the closing layer followed by phellem cell generation and maturation. Collectively, the genes monitored were wound-inducible and their expression profiles markedly coordinated with closing layer formation and the index for phellogen layer meristematic activity during wound periderm development; results were more influenced by harvest than genotype. Importantly, StTLRP was the only gene examined that may be involved in phellogen cell wall thickening after cessation of phellogen cell division. Published by Elsevier GmbH.

Antenna Linear-Quadratic-Gaussian (LQG) Ccontrollers: Properties, Limits of Performance, and Tuning

NASA Technical Reports Server (NTRS)

Gawronski, Wodek K.

2004-01-01

The LQG controllers significantly improve antenna tracking precision, but their tuning is a trial-and-error process. A control engineer has two tools to tune an LQG controller: the choice of coordinate system of the controller, and the selection of weights of the LQG performance index. The paper selects the coordinates of the open-loop model that simplify the shaping of the closed-loop performance. and analyzes the impact of thc weights on the antenna closed-loop bandwidth, disturbance rejection properties, and antenna acceleration. Finally, it presents the LQG controller tuning procedure that rationally shapes the closed-loop performance.

Homogenisation in project management for large German research projects in the Earth system sciences: overcoming the institutional coordination bias

NASA Astrophysics Data System (ADS)

Rauser, Florian; Vamborg, Freja

2016-04-01

The interdisciplinary project on High Definition Clouds and Precipitation for advancing climate prediction HD(CP)2 (hdcp2.eu) is an example for the trend in fundamental research in Europe to increasingly focus on large national and international research programs that require strong scientific coordination. The current system has traditionally been host-based: project coordination activities and funding is placed at the host institute of the central lead PI of the project. This approach is simple and has the advantage of strong collaboration between project coordinator and lead PI, while exhibiting a list of strong, inherent disadvantages that are also mentioned in this session's description: no community best practice development, lack of integration between similar projects, inefficient methodology development and usage, and finally poor career development opportunities for the coordinators. Project coordinators often leave the project before it is finalized, leaving some of the fundamentally important closing processes to the PIs. This systematically prevents the creation of professional science management expertise within academia, which leads to an automatic imbalance that hinders the outcome of large research programs to help future funding decisions. Project coordinators in academia often do not work in a professional project office environment that could distribute activities and use professional tools and methods between different projects. Instead, every new project manager has to focus on methodological work anew (communication infrastructure, meetings, reporting), even though the technological needs of large research projects are similar. This decreases the efficiency of the coordination and leads to funding that is effectively misallocated. We propose to challenge this system by creating a permanent, virtual "Centre for Earth System Science Management CESSMA" (cessma.com), and changing the approach from host- based to centre-based. This should complement the current system, by creating permanent, sustained options for interactions between large research projects in similar fields. In the long run such a centre might improve on the host-based system because the centre-based solution allows multiple projects to be coordinated in conjunction by experienced science managers, using overlap in meeting organization, reporting, infrastructure, travel and so on. To still maintain close cooperation between project managers and lead PIs, we envision a virtual centre that creates extensive collaborative opportunities by organizing yearly retreats, a shared technical data base, et cetera. As "CESSMA" is work in progress (we have applied for funding for 2016-18), we would like to use this opportunity to discuss chances, potential problems, experiences and options for this attempt to institutionalise the very reason for this session: improved, coordinated, effective science coordination; and to create a central focal point for public / academia interactions.

Coordinated Fuel Cell System Programs for Government and Commercial Applications: Are We in a New Era?

NASA Technical Reports Server (NTRS)

Warshay, Marvin; Prokopius, Paul

1996-01-01

Though the fuel cell was invented in 1839, it was not until the early 1960's that the fuel cell power system was developed and used for a real application, for the NASA Space Mission Gemini. Unfortunately, fuel cell power systems did not, as a result, become in widespread use. Nevertheless, a great deal of progress has been made by both government and industry, culminating in many successful fuel cell power system demonstrations. Initially, each government agency and each private organization went its own way. Later, it became evident that coordination among programs was essential. An overview is presented of the current coordinated efforts by government and industry in fuel cells, with a sufficient historical background. The primary barriers to coordination of programs were institutional and differing application requirements. Initially, in the institutional area, it was the energy crisis and the formation of DOE which fostered close working relationships among government, manufacturers, and users. The authors discuss the fuel cell power system programs (of NASA, DOE, DOT, DOC, EPRI, GRI, industry, and universities), including missions and applications, technology advances, and demonstrations. The discussion covers the new Solar Regenerative Fuel Cell (RFC) program which has space, defense, and commercial terrestrial applications, and which is an excellent example of both program coordination and the Clinton Administration's dual-use application policy.

Untangling cultural inheritance: language diversity and long-house architecture on the Pacific northwest coast

PubMed Central

Jordan, Peter; O'Neill, Sean

2010-01-01

Many recent studies of cultural inheritance have focused on small-scale craft traditions practised by single individuals, which do not require coordinated participation by larger social collectives. In this paper, we address this gap in the cultural transmission literature by investigating diversity in the vernacular architecture of the Pacific northwest coast, where communities of hunter–fisher–gatherers constructed immense wooden long-houses at their main winter villages. Quantitative analyses of long-house styles along the coastline draw on a range of models and methods from the biological sciences and are employed to test hypotheses relating to basic patterns of macro-scale cultural diversification, and the degree to which the transmission of housing traits has been constrained by the region's numerous linguistic boundaries. The results indicate relatively strong branching patterns of cultural inheritance and also close associations between regional language history and housing styles, pointing to the potentially crucial role played by language boundaries in structuring large-scale patterns of cultural diversification, especially in relation to ‘collective’ cultural traditions like housing that require substantial inputs of coordinated labour. PMID:21041212

Parallel Estimation and Control Architectures for Deep-Space Formation Flying Spacecraft

NASA Technical Reports Server (NTRS)

Hadaegh, Fred Y.; Smith, Roy S.

2006-01-01

The formation flying of precisely controlled spacecraft in deep space can be used to implement optical instruments capable of imaging planets in other solar systems. The distance of the formation from Earth necessitates a significant level of autonomy and each spacecraft must base its actions on its estimates of the location and velocity of the other spacecraft. Precise coordination and control is the key requirement in such missions and the flow of information between spacecraft must be carefully designed. Doing this in an efficient and optimal manner requires novel techniques for the design of the on-board estimators. The use of standard Kalman filter-based designs can lead to unanticipated dynamics--which we refer to as disagreement dynamics--in the estimators' errors. We show how communication amongst the spacecraft can be designed in order to control all of the dynamics within the formation. We present several results relating the topology of the communication network to the resulting closed-loop control dynamics of the formation. The consequences for the design of the control, communication and coordination are discussed.

National Science Foundation-sponsored workshop report. Draft plan for soybean genomics.

PubMed

Stacey, Gary; Vodkin, Lila; Parrott, Wayne A; Shoemaker, Randy C

2004-05-01

Recent efforts to coordinate and define a research strategy for soybean (Glycine max) genomics began with the establishment of a Soybean Genetics Executive Committee, which will serve as a communication focal point between the soybean research community and granting agencies. Secondly, a workshop was held to define a strategy to incorporate existing tools into a framework for advancing soybean genomics research. This workshop identified and ranked research priorities essential to making more informed decisions as to how to proceed with large scale sequencing and other genomics efforts. Most critical among these was the need to finalize a physical map and to obtain a better understanding of genome microstructure. Addressing these research needs will require pilot work on new technologies to demonstrate an ability to discriminate between recently duplicated regions in the soybean genome and pilot projects to analyze an adequate amount of random genome sequence to identify and catalog common repeats. The development of additional markers, reverse genetics tools, and bioinformatics is also necessary. Successful implementation of these goals will require close coordination among various working groups.

Registratiom of TM data to digital elevation models

NASA Technical Reports Server (NTRS)

1984-01-01

Several problems arise when attempting to register LANDSAT thematic mapper data to U.S. B Geological Survey digital elevation models (DEMs). The TM data are currently available only in a rotated variant of the Space Oblique Mercator (SOM) map projection. Geometric transforms are thus; required to access TM data in the geodetic coordinates used by the DEMs. Due to positional errors in the TM data, these transforms require some sort of external control. The spatial resolution of TM data exceeds that of the most commonly DEM data. Oversampling DEM data to TM resolution introduces systematic noise. Common terrain processing algorithms (e.g., close computation) compound this problem by acting as high-pass filters.

Software Engineering Improvement Plan

NASA Technical Reports Server (NTRS)

2006-01-01

In performance of this task order, bd Systems personnel provided support to the Flight Software Branch and the Software Working Group through multiple tasks related to software engineering improvement and to activities of the independent Technical Authority (iTA) Discipline Technical Warrant Holder (DTWH) for software engineering. To ensure that the products, comments, and recommendations complied with customer requirements and the statement of work, bd Systems personnel maintained close coordination with the customer. These personnel performed work in areas such as update of agency requirements and directives database, software effort estimation, software problem reports, a web-based process asset library, miscellaneous documentation review, software system requirements, issue tracking software survey, systems engineering NPR, and project-related reviews. This report contains a summary of the work performed and the accomplishments in each of these areas.

The ecology of markets.

PubMed Central

Nordhaus, W D

1992-01-01

Economies are sometimes viewed as analogous to ecological systems in which "everything is connected to everything else." In complex modern economies, the question arises whether the market mechanism can appropriately coordinate all the interconnections or whether instead some supramarket body is needed to coordinate the vast web of human activities. This study describes how an idealized decentralized competitive market in fact coordinates the different economic organisms in an efficient manner. The problems of pollution and other externalities can undo the efficient outcome unless corrected by appropriate property rights or corrective taxes. But in closing the economic circle, the internalized economy does not actually need to close the natural cycles by linking up all physical flows through recycling. PMID:11607264

Development of the Little Developmental Coordination Disorder Questionnaire for Preschoolers and Preliminary Evidence of Its Psychometric Properties in Israel

ERIC Educational Resources Information Center

Rihtman, Tanya; Wilson, Brenda N.; Parush, Shula

2011-01-01

Purpose: The early identification of motor coordination challenges before school age may enable close monitoring of a child's development and perhaps ameliorate some of the social, psychological and behavioral sequela that often accompany unrecognized Developmental Coordination Disorder (DCD). The purpose of this study was to develop and assess…

Closing the Gaps: 2014 Progress Report. College for All Texans

ERIC Educational Resources Information Center

Texas Higher Education Coordinating Board, 2014

2014-01-01

"Closing the Gaps: The Texas Higher Education Plan" was adopted in October 2000 by the Texas Higher Education Coordinating Board (THECB). The goal of the "Closing the Gaps" ("CTG") plan is to close educational gaps in participation, success, excellence, and research within Texas and between Texas and other states by…

Antenna Linear-Quadratic-Gaussian (LQG) Controllers: Properties, Limits of Performance, and Tuning Procedure

NASA Technical Reports Server (NTRS)

Gawronski, W.

2004-01-01

Wind gusts are the main disturbances that depreciate tracking precision of microwave antennas and radiotelescopes. The linear-quadratic-Gaussian (LQG) controllers - as compared with the proportional-and-integral (PI) controllers significantly improve the tracking precision in wind disturbances. However, their properties have not been satisfactorily understood; consequently, their tuning is a trial-and-error process. A control engineer has two tools to tune an LQG controller: the choice of coordinate system of the controller model and the selection of weights of the LQG performance index. This article analyzes properties of an open- and closed-loop antenna. It shows that the proper choice of coordinates of the open-loop model simplifies the shaping of the closed-loop performance. The closed-loop properties are influenced by the LQG weights. The article shows the impact of the weights on the antenna closed-loop bandwidth, disturbance rejection properties, and antenna acceleration. The bandwidth and the disturbance rejection characterize the antenna performance, while the acceleration represents the performance limit set by the antenna hardware (motors). The article presents the controller tuning procedure, based on the coordinate selection and the weight properties. The procedure rationally shapes the closed-loop performance, as an alternative to the trial-and-error approach.

Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I.

PubMed

Rebelo, Jorge; Auerbach, Günter; Bader, Gerd; Bracher, Andreas; Nar, Herbert; Hösl, Cornelia; Schramek, Nicholas; Kaiser, Johannes; Bacher, Adelbert; Huber, Robert; Fischer, Markus

2003-02-14

GTP cyclohydrolase I catalyses the hydrolytic release of formate from GTP followed by cyclization to dihydroneopterin triphosphate. The enzymes from bacteria and animals are homodecamers containing one zinc ion per subunit. Replacement of Cys110, Cys181, His112 or His113 of the enzyme from Escherichia coli by serine affords catalytically inactive mutant proteins with reduced capacity to bind zinc. These mutant proteins are unable to convert GTP or the committed reaction intermediate, 2-amino-5-formylamino-6-(beta-ribosylamino)-4(3H)-pyrimidinone 5'-triphosphate, to dihydroneopterin triphosphate. The crystal structures of GTP complexes of the His113Ser, His112Ser and Cys181Ser mutant proteins determined at resolutions of 2.5A, 2.8A and 3.2A, respectively, revealed the conformation of substrate GTP in the active site cavity. The carboxylic group of the highly conserved residue Glu152 anchors the substrate GTP, by hydrogen bonding to N-3 and to the position 2 amino group. Several basic amino acid residues interact with the triphosphate moiety of the substrate. The structure of the His112Ser mutant in complex with an undefined mixture of nucleotides determined at a resolution of 2.1A afforded additional details of the peptide folding. Comparison between the wild-type and mutant enzyme structures indicates that the catalytically active zinc ion is directly coordinated to Cys110, Cys181 and His113. Moreover, the zinc ion is complexed to a water molecule, which is in close hydrogen bond contact to His112. In close analogy to zinc proteases, the zinc-coordinated water molecule is suggested to attack C-8 of the substrate affording a zinc-bound 8R hydrate of GTP. Opening of the hydrated imidazole ring affords a formamide derivative, which remains coordinated to zinc. The subsequent hydrolysis of the formamide motif has an absolute requirement for zinc ion catalysis. The hydrolysis of the formamide bond shows close mechanistic similarity with peptide hydrolysis by zinc proteases.

45 CFR 162.1801 - Coordination of benefits transaction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Coordination of benefits transaction. 162.1801... RELATED REQUIREMENTS ADMINISTRATIVE REQUIREMENTS Coordination of Benefits § 162.1801 Coordination of benefits transaction. The coordination of benefits transaction is the transmission from any entity to a...

Closed Loop Interactions between Spiking Neural Network and Robotic Simulators Based on MUSIC and ROS.

PubMed

Weidel, Philipp; Djurfeldt, Mikael; Duarte, Renato C; Morrison, Abigail

2016-01-01

In order to properly assess the function and computational properties of simulated neural systems, it is necessary to account for the nature of the stimuli that drive the system. However, providing stimuli that are rich and yet both reproducible and amenable to experimental manipulations is technically challenging, and even more so if a closed-loop scenario is required. In this work, we present a novel approach to solve this problem, connecting robotics and neural network simulators. We implement a middleware solution that bridges the Robotic Operating System (ROS) to the Multi-Simulator Coordinator (MUSIC). This enables any robotic and neural simulators that implement the corresponding interfaces to be efficiently coupled, allowing real-time performance for a wide range of configurations. This work extends the toolset available for researchers in both neurorobotics and computational neuroscience, and creates the opportunity to perform closed-loop experiments of arbitrary complexity to address questions in multiple areas, including embodiment, agency, and reinforcement learning.

Closed Loop Interactions between Spiking Neural Network and Robotic Simulators Based on MUSIC and ROS

PubMed Central

Weidel, Philipp; Djurfeldt, Mikael; Duarte, Renato C.; Morrison, Abigail

2016-01-01

In order to properly assess the function and computational properties of simulated neural systems, it is necessary to account for the nature of the stimuli that drive the system. However, providing stimuli that are rich and yet both reproducible and amenable to experimental manipulations is technically challenging, and even more so if a closed-loop scenario is required. In this work, we present a novel approach to solve this problem, connecting robotics and neural network simulators. We implement a middleware solution that bridges the Robotic Operating System (ROS) to the Multi-Simulator Coordinator (MUSIC). This enables any robotic and neural simulators that implement the corresponding interfaces to be efficiently coupled, allowing real-time performance for a wide range of configurations. This work extends the toolset available for researchers in both neurorobotics and computational neuroscience, and creates the opportunity to perform closed-loop experiments of arbitrary complexity to address questions in multiple areas, including embodiment, agency, and reinforcement learning. PMID:27536234

The coordinated movement of the spine and pelvis during running.

PubMed

Preece, Stephen J; Mason, Duncan; Bramah, Christopher

2016-02-01

Previous research into running has demonstrated consistent patterns in pelvic, lumbar and thoracic motions between different human runners. However, to date, there has been limited attempt to explain why observed coordination patterns emerge and how they may relate to centre of mass (CoM) motion. In this study, kinematic data were collected from the thorax, lumbar spine, pelvis and lower limbs during over ground running in n=28 participants. These data was subsequently used to develop a theoretical understanding of the coordination of the spine and pelvis in all three body planes during the stance phase of running. In the sagittal plane, there appeared to be an antiphase coordinate pattern which may function to increase femoral inclination at toe off whilst minimising anterior-posterior accelerations of the CoM. In the medio-lateral direction, CoM motion appears to facilitate transition to the contralateral foot. However, an antiphase coordination pattern was also observed, most likely to minimise unnecessary accelerations of the CoM. In the transverse plane, motion of the pelvis was observed to lag slightly behind that of the thorax. However, it is possible that the close coupling between these two segments facilitates the thoracic rotation required to passively drive arm motion. This is the first study to provide a full biomechanical rationale for the coordination of the spine and pelvis during human running. This insight should help clinicians develop an improved understanding of how spinal and pelvic motions may contribute to, or result from, common running injuries. Copyright © 2015 Elsevier B.V. All rights reserved.

A fast algorithm for forward-modeling of gravitational fields in spherical coordinates with 3D Gauss-Legendre quadrature

NASA Astrophysics Data System (ADS)

Zhao, G.; Liu, J.; Chen, B.; Guo, R.; Chen, L.

2017-12-01

Forward modeling of gravitational fields at large-scale requires to consider the curvature of the Earth and to evaluate the Newton's volume integral in spherical coordinates. To acquire fast and accurate gravitational effects for subsurface structures, subsurface mass distribution is usually discretized into small spherical prisms (called tesseroids). The gravity fields of tesseroids are generally calculated numerically. One of the commonly used numerical methods is the 3D Gauss-Legendre quadrature (GLQ). However, the traditional GLQ integration suffers from low computational efficiency and relatively poor accuracy when the observation surface is close to the source region. We developed a fast and high accuracy 3D GLQ integration based on the equivalence of kernel matrix, adaptive discretization and parallelization using OpenMP. The equivalence of kernel matrix strategy increases efficiency and reduces memory consumption by calculating and storing the same matrix elements in each kernel matrix just one time. In this method, the adaptive discretization strategy is used to improve the accuracy. The numerical investigations show that the executing time of the proposed method is reduced by two orders of magnitude compared with the traditional method that without these optimized strategies. High accuracy results can also be guaranteed no matter how close the computation points to the source region. In addition, the algorithm dramatically reduces the memory requirement by N times compared with the traditional method, where N is the number of discretization of the source region in the longitudinal direction. It makes the large-scale gravity forward modeling and inversion with a fine discretization possible.

Maximum-likelihood-based extended-source spatial acquisition and tracking for planetary optical communications

NASA Astrophysics Data System (ADS)

Tsou, Haiping; Yan, Tsun-Yee

1999-04-01

This paper describes an extended-source spatial acquisition and tracking scheme for planetary optical communications. This scheme uses the Sun-lit Earth image as the beacon signal, which can be computed according to the current Sun-Earth-Probe angle from a pre-stored Earth image or a received snapshot taken by other Earth-orbiting satellite. Onboard the spacecraft, the reference image is correlated in the transform domain with the received image obtained from a detector array, which is assumed to have each of its pixels corrupted by an independent additive white Gaussian noise. The coordinate of the ground station is acquired and tracked, respectively, by an open-loop acquisition algorithm and a closed-loop tracking algorithm derived from the maximum likelihood criterion. As shown in the paper, the optimal spatial acquisition requires solving two nonlinear equations, or iteratively solving their linearized variants, to estimate the coordinate when translation in the relative positions of onboard and ground transceivers is considered. Similar assumption of linearization leads to the closed-loop spatial tracking algorithm in which the loop feedback signals can be derived from the weighted transform-domain correlation. Numerical results using a sample Sun-lit Earth image demonstrate that sub-pixel resolutions can be achieved by this scheme in a high disturbance environment.

32 CFR 153.4 - Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... General Counsel of the Department of Defense shall provide initial coordination and liaison with the... lead to successful prosecutions and, therefore, these cases warrant close coordination and cooperation... primary point of contact for DoD personnel regarding all investigations that may lead to criminal...

32 CFR 153.4 - Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... General Counsel of the Department of Defense shall provide initial coordination and liaison with the... lead to successful prosecutions and, therefore, these cases warrant close coordination and cooperation... primary point of contact for DoD personnel regarding all investigations that may lead to criminal...

32 CFR 153.4 - Responsibilities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... General Counsel of the Department of Defense shall provide initial coordination and liaison with the... lead to successful prosecutions and, therefore, these cases warrant close coordination and cooperation... primary point of contact for DoD personnel regarding all investigations that may lead to criminal...

32 CFR 153.4 - Responsibilities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... General Counsel of the Department of Defense shall provide initial coordination and liaison with the... lead to successful prosecutions and, therefore, these cases warrant close coordination and cooperation... primary point of contact for DoD personnel regarding all investigations that may lead to criminal...

76 FR 79151 - Forest Resource Coordinating Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-21

... DEPARTMENT OF AGRICULTURE Forest Service Forest Resource Coordinating Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Forest Resource Committee Meeting will meet in.... The meeting is partially closed to the public. The Forest Resource Committee is authorized under the...

47 CFR 27.903 - Coordination requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Coordination requirements. 27.903 Section 27.903 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1670-1675 MHz Band § 27.903 Coordination requirements. (a) The...

47 CFR 27.903 - Coordination requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 2 2011-10-01 2011-10-01 false Coordination requirements. 27.903 Section 27.903 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1670-1675 MHz Band § 27.903 Coordination requirements. (a) The...

Structures of M2(SO2)6B12F12 (M = Ag or K) and Ag2(H2O)4B12F12: Comparison of the Coordination of SO2 versus H2O and of B12F122- versus Other Weakly Coordinating Anions to Metal Ions in the Solid State.

PubMed

Malischewski, Moritz; Peryshkov, Dmitry V; Bukovsky, Eric V; Seppelt, Konrad; Strauss, Steven H

2016-12-05

The structures of three solvated monovalent cation salts of the superweak anion B 12 F 12 2- (Y 2- ), K 2 (SO 2 ) 6 Y, Ag 2 (SO 2 ) 6 Y, and Ag 2 (H 2 O) 4 Y, are reported and discussed with respect to previously reported structures of Ag + and K + with other weakly coordinating anions. The structures of K 2 (SO 2 ) 6 Y and Ag 2 (SO 2 ) 6 Y are isomorphous and are based on expanded cubic close-packed arrays of Y 2- anions with M(OSO) 6 + complexes centered in the trigonal holes of one expanded close-packed layer of B 12 centroids (⊙). The K + and Ag + ions have virtually identical bicapped trigonal prism MO 6 F 2 coordination spheres, with M-O distances of 2.735(1)-3.032(2) Å for the potassium salt and 2.526(5)-2.790(5) Å for the silver salt. Each M(OSO) 6 + complex is connected to three other cationic complexes through their six μ-SO 2 -κ 1 O,κ 2 O' ligands. The structure of Ag 2 (H 2 O) 4 Y is unique [different from that of K 2 (H 2 O) 4 Y]. Planes of close-packed arrays of anions are offset from neighboring planes along only one of the linear ⊙···⊙···⊙ directions of the close-packed arrays, with [Ag(μ-H 2 O) 2 Ag(μ-H 2 O) 2 )] ∞ infinite chains between the planes of anions. There are two nearly identical AgO 4 F 2 coordination spheres, with Ag-O distances of 2.371(5)-2.524(5) Å and Ag-F distances of 2.734(4)-2.751(4) Å. This is only the second structurally characterized compound with four H 2 O molecules coordinated to a Ag + ion in the solid state. Comparisons with crystalline H 2 O and SO 2 solvates of other Ag + and K + salts of weakly coordinating anions show that (i) N[(SO 2 ) 2 (1,2-C 6 H 4 )] - , BF 4 - , SbF 6 - , and Al(OC(CF 3 ) 3 ) 4 - coordinate much more strongly to Ag + than does Y 2- , (ii) SnF 6 2- coordinates somewhat more strongly to K + than does Y 2- , and (iii) B 12 Cl 12 2- coordinates to K + about the same as, if not slightly weaker than, Y 2- .

International Outreach and Coordination Strategy for the National Strategy for Maritime Security

DTIC Science & Technology

2005-11-01

economic stability of the international community, all nations have a vital interest in ensuring that the maritime domain remains secure and open for the free and legitimate use of all. Public and private entities must work in concert to succeed. Accordingly, in order to enhance global maritime security, the Department of State will leverage its diplomatic resources and influence, while coordinating closely with other components of the US Government, to promote and enhance close cooperation among sovereign nations, international and regional organizations and the maritime

Mixed martial arts: injury patterns and issues for the ringside physician.

PubMed

Seidenberg, Peter H

2011-01-01

Mixed martial arts (MMA) is a fast-growing combat sport. There are limited studies investigating MMA's injury incidence. However, from the data available, closed head injuries and lacerations commonly are experienced by competitors. Sanctioned events require the presence of ringside physicians, who should be well versed in handling these types of injuries. Additionally, sports-medicine providers should have an appropriately equipped medical bag, and before providing coverage, they need to coordinate with emergency medical personnel in order to more efficiently deliver care if urgent situations arise. More research is needed on injury incidence and prevention in MAA.

EMI / EMC Design for Class D Payloads (Resource Prospector / NIRVSS)

NASA Technical Reports Server (NTRS)

Forgione, Josh; Benton, Joshua Eric; Thompson, Sarah; Colaprete, Anthony

2015-01-01

EMI/EMC techniques are applied to a Class D instrument (NIRVSS) to achieve low noise performance and reduce risk of EMI/EMC testing failures and/or issues during system integration and test. Basic techniques are not terribly expensive or complex, but do require close coordination between electrical and mechanical staff early in the design process. Low-cost methods to test subsystems on the bench without renting an EMI chamber are discussed. This method was applied to the NIRVSS instrument and achieved improvements up to 59dB on conducted emissions measurements between hardware revisions.

Illustration and analysis of a coordinated approach to an effective forensic trace evidence capability.

PubMed

Stoney, David A; Stoney, Paul L

2015-08-01

An effective trace evidence capability is defined as one that exploits all useful particle types, chooses appropriate technologies to do so, and directly integrates the findings with case-specific problems. Limitations of current approaches inhibit the attainment of an effective capability and it has been strongly argued that a new approach to trace evidence analysis is essential. A hypothetical case example is presented to illustrate and analyze how forensic particle analysis can be used as a powerful practical tool in forensic investigations. The specifics in this example, including the casework investigation, laboratory analyses, and close professional interactions, provide focal points for subsequent analysis of how this outcome can be achieved. This leads to the specification of five key elements that are deemed necessary and sufficient for effective forensic particle analysis: (1) a dynamic forensic analytical approach, (2) concise and efficient protocols addressing particle combinations, (3) multidisciplinary capabilities of analysis and interpretation, (4) readily accessible external specialist resources, and (5) information integration and communication. A coordinating role, absent in current approaches to trace evidence analysis, is essential to achieving these elements. However, the level of expertise required for the coordinating role is readily attainable. Some additional laboratory protocols are also essential. However, none of these has greater staffing requirements than those routinely met by existing forensic trace evidence practitioners. The major challenges that remain are organizational acceptance, planning and implementation. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Accountable care organization readiness and academic medical centers.

PubMed

Berkowitz, Scott A; Pahira, Jennifer J

2014-09-01

As academic medical centers (AMCs) consider becoming accountable care organizations (ACOs) under Medicare, they must assess their readiness for this transition. Of the 253 Medicare ACOs prior to 2014, 51 (20%) are AMCs. Three critical components of ACO readiness are institutional and ACO structure, leadership, and governance; robust information technology and analytic systems; and care coordination and management to improve care delivery and health at the population level. All of these must be viewed through the lens of unique AMC mission-driven goals.There is clear benefit to developing and maintaining a centralized internal leadership when it comes to driving change within an ACO, yet there is also the need for broad stakeholder involvement. Other important structural features are an extensive primary care foundation; concomitant operation of a managed care plan or risk-bearing entity; or maintaining a close relationship with post-acute-care or skilled nursing facilities, which provide valuable expertise in coordinating care across the continuum. ACOs also require comprehensive and integrated data and analytic systems that provide meaningful population data to inform care teams in real time, promote quality improvement, and monitor spending trends. AMCs will require proven care coordination and management strategies within a population health framework and deployment of an innovative workforce.AMC core functions of providing high-quality subspecialty and primary care, generating new knowledge, and training future health care leaders can be well aligned with a transition to an ACO model. Further study of results from Medicare-related ACO programs and commercial ACOs will help define best practices.

Environmental considerations for 3D seismic in Louisianna wetlands

DOE Office of Scientific and Technical Information (OSTI.GOV)

Browning, G.; Dillane, T.; Baaren, P. van

1996-11-01

Louisiana swamps have been host to seismic crews for many years. Results from recent 3D surveys indicate that well planned and executed seismic operations have a minimal and short term impact in these environmentally sensitive wetlands. Pre-planning identifies challenges that require use of improved technology and work procedures. These include multi-channel radio telemetry recording systems, ramming of dynamite and hydrophones as opposed to drilling, DGPS positioning and coordinated use of Airboats, buggies and helicopters. In addition to minimal environmental impact, increased data quality, reduced cost and shorter project duration have been achieved as a result of these efforts. Unlike 2Dmore » surveys, where profile positioning is flexible, 3D surveys involve high density coverage over many square miles operated by numerous personnel. Survey design includes minimizing repeated traffic and crossing points. Survey operations require environmental participation and commitment from every person involved in the project. This includes a thorough orientation and training program with strong emphasis on environmental sensitivity and awareness. Close co-ordination between regulatory agencies, clients and the contractor is a key factor in all aspects of the survey planning and operation. Benefits from these efforts are significant, measurable and continue to improve.« less

Decentralized coordinated control of elastic web winding systems without tension sensor.

PubMed

Hou, Hailiang; Nian, Xiaohong; Chen, Jie; Xiao, Dengfeng

2018-06-26

In elastic web winding systems, precise regulation of web tension in each span is critical to ensure final product quality, and to achieve low cost by reducing the occurrence of web break or fold. Generally, web winding systems use load cells or swing rolls as tension sensors, which add cost, reduce system reliability and increase the difficulty of control. In this paper, a decentralized coordinated control scheme with tension observers is designed for a three-motor web-winding system. First, two tension observers are proposed to estimate the unwinding and winding tension. The designed observers consider the essential dynamic, radius, and inertial variation effects and only require the modest computational effort. Then, using the estimated tensions as feedback signals, a robust decentralized coordinated controller is adopted to reduce the interaction between subsystems. Asymptotic stabilities of the observer error dynamics and the closed-loop winding systems are demonstrated via Lyapunov stability theory. The observer gains and the controller gains can be obtained by solving matrix inequalities. Finally, some simulations and experiments are performed on a paper winding setup to test the performance of the designed observers and the observer-base DCC method, respectively. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

New coordination features; A bridging pyridine and the forced shortest non-covalent distance between two CO 3 2- species

DOE PAGES

Velasco, V.; Aguilà, D.; Barrios, L. A.; ...

2014-09-29

The aerobic reaction of the multidentate ligand 2,6-bis-(3-oxo-3-(2-hydroxyphenyl)-propionyl)-pyridine, H 4L, with Co (II) salts in strong basic conditions produces the clusters [Co 4(L) 2(OH)(py) 7]NO 3 (1) and [Co 8Na 4(L) 4(OH) 2(CO 3) 2(py) 10](BF 4) 2 (2). Analysis of their structure unveils unusual coordination features including a very rare bridging pyridine ligand or two trapped carbonate anions within one coordination cage, forced to stay at an extremely close distance (d O···O = 1.946 Å). This unprecedented non-bonding proximity represents a meeting point between long covalent interactions and “intermolecular” contacts. These original motifs have been analysed here through DFTmore » calculations, which have yielded interaction energies and the reduced repulsion energy experimented by both CO 3 2- anions when located in close proximity inside the coordination cage.« less

Description of the AILS Alerting Algorithm

NASA Technical Reports Server (NTRS)

Samanant, Paul; Jackson, Mike

2000-01-01

This document provides a complete description of the Airborne Information for Lateral Spacing (AILS) alerting algorithms. The purpose of AILS is to provide separation assurance between aircraft during simultaneous approaches to closely spaced parallel runways. AILS will allow independent approaches to be flown in such situations where dependent approaches were previously required (typically under Instrument Meteorological Conditions (IMC)). This is achieved by providing multiple levels of alerting for pairs of aircraft that are in parallel approach situations. This document#s scope is comprehensive and covers everything from general overviews, definitions, and concepts down to algorithmic elements and equations. The entire algorithm is presented in complete and detailed pseudo-code format. This can be used by software programmers to program AILS into a software language. Additional supporting information is provided in the form of coordinate frame definitions, data requirements, calling requirements as well as all necessary pre-processing and post-processing requirements. This is important and required information for the implementation of AILS into an analysis, a simulation, or a real-time system.

On the long-term stability of terrestrial reference frame solutions based on Kalman filtering

NASA Astrophysics Data System (ADS)

Soja, Benedikt; Gross, Richard S.; Abbondanza, Claudio; Chin, Toshio M.; Heflin, Michael B.; Parker, Jay W.; Wu, Xiaoping; Nilsson, Tobias; Glaser, Susanne; Balidakis, Kyriakos; Heinkelmann, Robert; Schuh, Harald

2018-06-01

The Global Geodetic Observing System requirement for the long-term stability of the International Terrestrial Reference Frame is 0.1 mm/year, motivated by rigorous sea level studies. Furthermore, high-quality station velocities are of great importance for the prediction of future station coordinates, which are fundamental for several geodetic applications. In this study, we investigate the performance of predictions from very long baseline interferometry (VLBI) terrestrial reference frames (TRFs) based on Kalman filtering. The predictions are computed by extrapolating the deterministic part of the coordinate model. As observational data, we used over 4000 VLBI sessions between 1980 and the middle of 2016. In order to study the predictions, we computed VLBI TRF solutions only from the data until the end of 2013. The period of 2014 until 2016.5 was used to validate the predictions of the TRF solutions against the measured VLBI station coordinates. To assess the quality, we computed average WRMS values from the coordinate differences as well as from estimated Helmert transformation parameters, in particular, the scale. We found that the results significantly depend on the level of process noise used in the filter. While larger values of process noise allow the TRF station coordinates to more closely follow the input data (decrease in WRMS of about 45%), the TRF predictions exhibit larger deviations from the VLBI station coordinates after 2014 (WRMS increase of about 15%). On the other hand, lower levels of process noise improve the predictions, making them more similar to those of solutions without process noise. Furthermore, our investigations show that additionally estimating annual signals in the coordinates does not significantly impact the results. Finally, we computed TRF solutions mimicking a potential real-time TRF and found significant improvements over the other investigated solutions, all of which rely on extrapolating the coordinate model for their predictions, with WRMS reductions of almost 50%.

Worker piping triggers hissing for coordinated colony defence in the dwarf honeybee Apis florea.

PubMed

Sen Sarma, Moushumi; Fuchs, Stefan; Werber, Christian; Tautz, Jürgen

2002-01-01

Defending a large social insect colony containing several thousands of workers requires the simultaneous action of many individuals. Ideally this action involves communication between the workers, enabling coordinated action and a fast response. The Asian dwarf honeybee, Apis florea, is a small honeybee with an open nesting habit and a comparatively small colony size, features that leave them particularly exposed to predators. We describe here a novel defence response of these bees in which the emission of an initial warning signal from one individual ("piping") is followed 0.3 to 0.7 seconds later by a general response from a large number of bees ("hissing"). Piping is audible to the human ear, with a fundamental frequency of 384 +/- 31Hz and lasting for 0.82 +/- 0.35 seconds. Hissing is a broad band, noisy signal, clearly audible to the human observer and produced by slight but visible movements of the bees' wings. Hissing begins in individuals close to the piping bee, spreads rapidly to neighbours and results in an impressive coordinated crescendo occasionally involving the entire colony. Piping and hissing are accompanied by a marked decrease, or even cessation, of worker activities such as forager dancing and departures from the colony. We show that whereas hissing of the colony can be elicited without piping, the sequential and correlated piping and hissing response is specific to the presence of potential predators close to the colony. We suggest that the combined audio-visual effect of the hissing might deter small predators, while the cessation of flight activity could decrease the risk of predation by birds and insects which prey selectively on flying bees.

Ellipsoidal terrain correction based on multi-cylindrical equal-area map projection of the reference ellipsoid

NASA Astrophysics Data System (ADS)

Ardalan, A. A.; Safari, A.

2004-09-01

An operational algorithm for computation of terrain correction (or local gravity field modeling) based on application of closed-form solution of the Newton integral in terms of Cartesian coordinates in multi-cylindrical equal-area map projection of the reference ellipsoid is presented. Multi-cylindrical equal-area map projection of the reference ellipsoid has been derived and is described in detail for the first time. Ellipsoidal mass elements with various sizes on the surface of the reference ellipsoid are selected and the gravitational potential and vector of gravitational intensity (i.e. gravitational acceleration) of the mass elements are computed via numerical solution of the Newton integral in terms of geodetic coordinates {λ,ϕ,h}. Four base- edge points of the ellipsoidal mass elements are transformed into a multi-cylindrical equal-area map projection surface to build Cartesian mass elements by associating the height of the corresponding ellipsoidal mass elements to the transformed area elements. Using the closed-form solution of the Newton integral in terms of Cartesian coordinates, the gravitational potential and vector of gravitational intensity of the transformed Cartesian mass elements are computed and compared with those of the numerical solution of the Newton integral for the ellipsoidal mass elements in terms of geodetic coordinates. Numerical tests indicate that the difference between the two computations, i.e. numerical solution of the Newton integral for ellipsoidal mass elements in terms of geodetic coordinates and closed-form solution of the Newton integral in terms of Cartesian coordinates, in a multi-cylindrical equal-area map projection, is less than 1.6×10-8 m2/s2 for a mass element with a cross section area of 10×10 m and a height of 10,000 m. For a mass element with a cross section area of 1×1 km and a height of 10,000 m the difference is less than 1.5×10-4m2/s2. Since 1.5× 10-4 m2/s2 is equivalent to 1.5×10-5m in the vertical direction, it can be concluded that a method for terrain correction (or local gravity field modeling) based on closed-form solution of the Newton integral in terms of Cartesian coordinates of a multi-cylindrical equal-area map projection of the reference ellipsoid has been developed which has the accuracy of terrain correction (or local gravity field modeling) based on the Newton integral in terms of ellipsoidal coordinates.

Healthier students are better learners: high-quality, strategically planned, and effectively coordinated school health programs must be a fundamental mission of schools to help close the achievement gap.

PubMed

Basch, Charles E

2011-10-01

To discuss implications for educational policy and practice relevant to closing the achievement gap based on the literature review and synthesis presented in 7 articles of the October 2011 special issue of the Journal of School Health. Implications for closing the achievement gap are drawn from analyses of current literature. During the past several decades, school reform efforts to close the achievement gap have focused on various strategies, yielding very limited progress. Educationally relevant health disparities influence students' motivation and ability to learn, but reducing these disparities has been largely overlooked as an element of an overall strategy for closing the achievement gap. If these health problems are not addressed, the educational benefits of other school reform efforts will be jeopardized. Healthier students are better learners. School health programs and services that are evidence based, strategically planned to influence academic achievement, and effectively coordinated warrant validation as a cohesive school improvement initiative for closing the achievement gap. National, state, and local responsibilities for supporting school health are outlined, including shared strategies; leadership from the U.S. Department of Education; policy development; guidance, technical assistance, and professional development; accountability and data and software systems; and a research agenda. To date, the U.S. Department of Education has not provided leadership for integrating evidence-based, strategically planned, and effectively coordinated school health programs and services into the fundamental mission of schools. Now is an opportune time for change. © 2011, American School Health Association.

Underwater photogrammetric theoretical equations and technique

NASA Astrophysics Data System (ADS)

Fan, Ya-bing; Huang, Guiping; Qin, Gui-qin; Chen, Zheng

2011-12-01

In order to have a high level of accuracy of measurement in underwater close-range photogrammetry, this article deals with a study of three varieties of model equations according to the way of imaging upon the water. First, the paper makes a careful analysis for the two varieties of theoretical equations and finds out that there are some serious limitations in practical application and has an in-depth study for the third model equation. Second, one special project for this measurement has designed correspondingly. Finally, one rigid antenna has been tested by underwater photogrammetry. The experimental results show that the precision of 3D coordinates measurement is 0.94mm, which validates the availability and operability in practical application with this third equation. It can satisfy the measurement requirements of refraction correction, improving levels of accuracy of underwater close-range photogrammetry, as well as strong antijamming and stabilization.

The Minkowski metric in non-inertial observer radar coordinates

NASA Astrophysics Data System (ADS)

Minguzzi, E.

2005-12-01

We give a closed expression for the Minkowski (1+1)-dimensional metric in the radar coordinates of an arbitrary non-inertial observer O in terms of O's proper acceleration. Knowledge of the metric allows the non-inertial observer to perform experiments in spacetime without making reference to inertial frames. To clarify the relation between inertial and non-inertial observers the coordinate transformation between radar and inertial coordinates also is given. We show that every conformally flat coordinate system can be regarded as the radar coordinate system of a suitable observer for a suitable parametrization of the observer worldline. Therefore, the coordinate transformation between arbitrarily moving observers is a conformal transformation and conformally invariant (1+1)-dimensional theories lead to the same physics for all observers, independently of their relative motion.

The Heliophysics Integrated Observatory

NASA Astrophysics Data System (ADS)

Csillaghy, A.; Bentley, R. D.

2009-12-01

HELIO is a new Europe-wide, FP7-funded distributed network of services that will address the needs of a broad community of researchers in heliophysics. This new research field explores the “Sun-Solar System Connection” and requires the joint exploitation of solar, heliospheric, magnetospheric and ionospheric observations. HELIO will provide the most comprehensive integrated information system in this domain; it will coordinate access to the distributed resources needed by the community, and will provide access to services to mine and analyse the data. HELIO will be designed as a Service-oriented Architecture. The initial infrastructure will include services based on metadata and data servers deployed by the European Grid of Solar Observations (EGSO). We will extend these to address observations from all the disciplines of heliophysics; differences in the way the domains describe and handle the data will be resolved using semantic mapping techniques. Processing and storage services will allow the user to explore the data and create the products that meet stringent standards of interoperability. These capabilities will be orchestrated with the data and metadata services using the Taverna workflow tool. HELIO will address the challenges along the FP7 I3 activities model: (1) Networking: we will cooperate closely with the community to define new standards for heliophysics and the required capabilities of the HELIO system. (2) Services: we will integrate the services developed by the project and other groups to produce an infrastructure that can easily be extended to satisfy the growing and changing needs of the community. (3) Joint Research: we will develop search tools that span disciplinary boundaries and explore new types of user-friendly interfaces HELIO will be a key component of a worldwide effort to integrate heliophysics data and will coordinate closely with international organizations to exploit synergies with complementary domains.

Enhanced Cognitive Rehabilitation to Treat Comorbid TBI and PTSD

DTIC Science & Technology

2015-10-01

study brochures more widely to other relevant clinics within the VA (e.g., Member Services, Polytrauma , Social Work). The study coordinator 5  has also...In addition, the study coordinator worked closely with the Polytrauma Clinic at the VA to build a more efficient system to reach Veterans who are

Deranged jaw-neck motor control in whiplash-associated disorders.

PubMed

Eriksson, Per-Olof; Zafar, Hamayun; Häggman-Henrikson, Birgitta

2004-02-01

Recent findings of simultaneous and well coordinated head-neck movements during single as well as rhythmic jaw opening-closing tasks has led to the conclusion that 'functional jaw movements' are the result of activation of jaw as well as neck muscles, leading to simultaneous movements in the temporomandibular, atlanto-occipital and cervical spine joints. It can therefore be assumed that disease or injury to any of these joint systems would disturb natural jaw function. To test this hypothesis, amplitudes, temporal coordination, and spatiotemporal consistency of concomitant mandibular and head-neck movements during single maximal jaw opening-closing tasks were analysed in 25 individuals suffering from whiplash-associated disorders (WAD) using optoelectronic movement recording technique. In addition, the relative durations for which the head position was equal to, leading ahead of, or lagging behind the mandibular position during the entire jaw opening-closing cycle were determined. Compared with healthy individuals, the WAD group showed smaller amplitudes, and changed temporal coordination between mandibular and head-neck movements. No divergence from healthy individuals was found for the spatiotemporal consistency or for the analysis during the entire jaw opening-closing cycle. These findings in the WAD group of a 'faulty', but yet consistent, jaw-neck behavior may reflect a basic importance of linked control of the jaw and neck sensory-motor systems. In conclusion, the present results suggest that neck injury is associated with deranged control of mandibular and head-neck movements during jaw opening-closing tasks, and therefore might compromise natural jaw function.

A molecular dynamics study of the atomic structure of (CaO)x(Al2O3)1-x glass with x = 0.625 close to the eutectic

NASA Astrophysics Data System (ADS)

Thomas, B. W. M.; Mead, R. N.; Mountjoy, G.

2006-05-01

Aluminate glasses are difficult to prepare as they do not contain traditional network formers, but they are promising materials for optical applications. The atomic structure of calcium aluminate glasses has been studied using several experimental techniques. The current study uses molecular dynamics to obtain a model of a (CaO)0.625(Al2O3)0.375 glass close to the eutectic. The glass consists of a tetrahedral alumina network with average network polymerization \\langle Q^{n}\\rangle of n = 3.3. Ca acts as a network modifier with average coordination of 6.2. Ca is typically coordinated to three bridging oxygens (Ob) and three non-bridging oxygens (Onb), with Ca-Onb bonds noticeably shorter than the Ca-Ob bonds. A new method of analysing modifier cation coordination is presented, which specifically shows the distribution of Ca coordination NCaO in terms of combinations of NCaOb and NCaOnb. Ob is most often coordinated to two Al plus two Ca, and Onb is most often coordinated to one Al plus three Ca. The typical coordinations of Ca, Ob, and Onb all have a noticeable similarity to those for the 5CaO·3Al2O3 crystal. The Ca-Ca distribution shows a clear similarity to that for (CaO)0.5(SiO2)0.5 glass, and this is attributed to the equal atomic number densities of Ca in these glasses.

26 CFR 1.411(d)-1 - Coordination of vesting and discrimination requirements. [Reserved

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Coordination of vesting and discrimination requirements. [Reserved] 1.411(d)-1 Section 1.411(d)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF... Plans, Etc. § 1.411(d)-1 Coordination of vesting and discrimination requirements. [Reserved] ...

Modeling the Scheduling of Eye Movements and Manual Responses in Performing a Sequence of Discrete Tasks

NASA Technical Reports Server (NTRS)

Wu, Shu-Chieh; Remington, Roger W.; Lewis, Richard

2006-01-01

Common tasks in daily life are often accomplished by a sequence of actions that interleave information acquisition through the eyes and action execution by the hands. How are eye movements coordinated with the release of manual responses and how may their coordination be represented at the level of component mental operations? We have previously presented data from a typing-like task requiring separate choice responses to a series of five stimuli. We found a consistent pattern of results in both motor and ocular timing, and hypothesized possible relationships among underlying components. Here we report a model of that task, which demonstrates how the observed timing of eye movements to successive stimuli could be accounted for by assuming systems: an open-loop system generating saccades at a periodic rate, and a closed-loop system commanding a saccade based on stimulus processing. We relate this model to models of reading and discuss the motivation for dual control.

Damped-Dynamics Flexible Fitting

PubMed Central

Kovacs, Julio A.; Yeager, Mark; Abagyan, Ruben

2008-01-01

In fitting atomic structures into EM maps, it often happens that the map corresponds to a different conformation of the structure. We have developed a new methodology to handle these situations that preserves the covalent geometry of the structure and allows the modeling of large deformations. The first goal is achieved by working in generalized coordinates (positional and internal coordinates), and the second by avoiding harmonic potentials. Instead, we use dampers (shock absorbers) between every pair of atoms, combined with a force field that attracts the atomic structure toward incompletely occupied regions of the EM map. The trajectory obtained by integrating the resulting equations of motion converges to a conformation that, in our validation cases, was very close to the target atomic structure. Compared to current methods, our approach is more efficient and robust against wrong solutions and to overfitting, and does not require user intervention or subjective decisions. Applications to the computation of transition pathways between known conformers, homology and loop modeling, as well as protein docking, are also discussed. PMID:18586844

Damped-dynamics flexible fitting.

PubMed

Kovacs, Julio A; Yeager, Mark; Abagyan, Ruben

2008-10-01

In fitting atomic structures into EM maps, it often happens that the map corresponds to a different conformation of the structure. We have developed a new methodology to handle these situations that preserves the covalent geometry of the structure and allows the modeling of large deformations. The first goal is achieved by working in generalized coordinates (positional and internal coordinates), and the second by avoiding harmonic potentials. Instead, we use dampers (shock absorbers) between every pair of atoms, combined with a force field that attracts the atomic structure toward incompletely occupied regions of the EM map. The trajectory obtained by integrating the resulting equations of motion converges to a conformation that, in our validation cases, was very close to the target atomic structure. Compared to current methods, our approach is more efficient and robust against wrong solutions and to overfitting, and does not require user intervention or subjective decisions. Applications to the computation of transition pathways between known conformers, homology and loop modeling, as well as protein docking, are also discussed.

Using Image Pro Plus Software to Develop Particle Mapping on Genesis Solar Wind Collector Surfaces

NASA Technical Reports Server (NTRS)

Rodriquez, Melissa C.; Allton, J. H.; Burkett, P. J.

2012-01-01

The continued success of the Genesis mission science team in analyzing solar wind collector array samples is partially based on close collaboration of the JSC curation team with science team members who develop cleaning techniques and those who assess elemental cleanliness at the levels of detection. The goal of this collaboration is to develop a reservoir of solar wind collectors of known cleanliness to be available to investigators. The heart and driving force behind this effort is Genesis mission PI Don Burnett. While JSC contributes characterization, safe clean storage, and benign collector cleaning with ultrapure water (UPW) and UV ozone, Burnett has coordinated more exotic and rigorous cleaning which is contributed by science team members. He also coordinates cleanliness assessment requiring expertise and instruments not available in curation, such as XPS, TRXRF [1,2] and synchrotron TRXRF. JSC participates by optically documenting the particle distributions as cleaning steps progress. Thus, optical document supplements SEM imaging and analysis, and elemental assessment by TRXRF.

Coordinate regulation of cytochrome and alternative pathway respiration in tobacco.

PubMed

Vanlerberghe, G C; McIntosh, L

1992-12-01

In suspension cells of NT1 tobacco (Nicotiana tabacum L. cv bright yellow), inhibition of the cytochrome pathway of respiration with antimycin A induced a large increase in the capacity of the alternative pathway over a period of approximately 12 h, as confirmed in both whole cells and isolated mitochondria. The increase in alternative pathway capacity required de novo RNA and protein synthesis and correlated closely with the increase of a 35-kD alternative oxidase protein. When the cytochrome pathway of intact cells was inhibited by antimycin A, respiration proceeded exclusively through the alternative pathway, reached rates significantly higher than before antimycin A addition, and was not stimulated by p-trifluoromethoxycarbonylcyanide (FCCP). When inhibition of the cytochrome pathway was relieved, alternative pathway capacity and the level of the 35-kD alternative oxidase protein declined. Respiration rate also declined and could once again be stimulated by FCCP. These observations show that the capacities of the mitochondrial electron transport pathways can be regulated in a coordinate fashion.

Coordination success and interpersonal perceptions: matching versus mismatching.

PubMed

Abele, Susanne; Stasser, Garold

2008-09-01

Coordination is an essential part of social functioning. The authors distinguish 2 types of coordination: matching and mismatching. In matching, coordination is successful if parties choose the same action. In mismatching, coordination is successful if people choose different actions. In 3 studies, the authors investigated the downstream social consequences of tacit coordination for interpersonal perceptions. In all studies, participants repeatedly choose between 2 bets with equivalent expected values, and payoffs increased either when they choose the same bet or when they choose different bets. In the 1st 2 studies, coordination success increased the perceptions of interpersonal similarity and liking when matching was required but not when mismatching was required. The authors' interpretation is that matching responses and coordination success had countervailing effects in the mismatching task. Also, percentage of matched responses did not affect perceptions when coordination was not required (Experiment 2). In 4 person teams, a frequently matching partner was viewed more favorably (smarter, more similar to self, and more liked) than were other teammates, even when mismatching increased payoffs (Experiment 3).

Optical Closed-Loop Propulsion Control System Development

NASA Technical Reports Server (NTRS)

Poppel, Gary L.

1998-01-01

The overall objective of this program was to design and fabricate the components required for optical closed-loop control of a F404-400 turbofan engine, by building on the experience of the NASA Fiber Optic Control System Integration (FOCSI) program. Evaluating the performance of fiber optic technology at the component and system levels will result in helping to validate its use on aircraft engines. This report includes descriptions of three test plans. The EOI Acceptance Test is designed to demonstrate satisfactory functionality of the EOI, primarily fail-safe throughput of the F404 sensor signals in the normal mode, and validation, switching, and output of the five analog sensor signals as generated from validated optical sensor inputs, in the optical mode. The EOI System Test is designed to demonstrate acceptable F404 ECU functionality as interfaced with the EOI, making use of a production ECU test stand. The Optical Control Engine Test Request describes planned hardware installation, optical signal calibrations, data system coordination, test procedures, and data signal comparisons for an engine test demonstration of the optical closed-loop control.

Effects of calisthenics and Pilates exercises on coordination and proprioception in adult women: a randomized controlled trial.

PubMed

Ozer Kaya, Derya; Duzgun, Irem; Baltaci, Gul; Karacan, Selma; Colakoglu, Filiz

2012-08-01

To assess and compare the effects of 6 mo of Pilates and calisthenics on multijoint coordination and proprioception of the lower limbs at the 3rd and 6th mo of training. Randomized, controlled, assessor-blinded, repeated-measures. University research laboratory. Healthy, sedentary, female participants age 25-50 y were recruited and randomly divided into 3 groups: a calisthenic exercise group (n = 34, mean age ± SD 40 ± 8 y, body-mass index [BMI] 31.04 ± 4.83 kg/m2), a Pilates exercise group (n = 32, mean age ± SD 37 ± 8 y, BMI 31.04 ± 4.83 kg/m2), and a control group (n = 41, mean age ± SD 41 ± 7 y, BMI 27.09 ± 4.77 kg/m2). The calisthenics and Pilates groups underwent related training programs for 6 mo, while the controls had no specific training. Coordination and proprioception of the lower extremities with concentric and eccentric performances in the closed kinetic chain assessed with the monitored rehab functional squat system at baseline and at the 3rd and 6th mo of training. For the within-group comparison, coordinative concentric and eccentric deviation values were significantly decreased for both dominant and nondominant lower limbs at pretraining and at the 3rd and 6th mo posttraining in the calisthenics group (P < .05). In contrast, there was no improvement in the Pilates group throughout the training. However, for comparisons between groups, the baseline values of coordinative concentric and eccentric deviations were different in the calisthenics group than in Pilates and the controls (P < .05). There were no differences in the proprioception values of either visible or nonvisible movement in any group throughout the training (P > .05). It seems that calisthenic exercises are more likely to improve coordination of the lower extremity after 3 and 6 mo of training than Pilates exercises. Calisthenic exercises may be useful for individuals who require improved coordination.

20 CFR 30.627 - Under what circumstances will OWCP waive the statutory requirement to coordinate these benefits?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Under what circumstances will OWCP waive the statutory requirement to coordinate these benefits? 30.627 Section 30.627 Employees' Benefits OFFICE OF...' Compensation Benefits § 30.627 Under what circumstances will OWCP waive the statutory requirement to coordinate...

48 CFR 970.5223-7 - Sustainable acquisition program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... coordinate its activities with and submit required reports through the Environmental Sustainability... clause, the Contractor shall coordinate its activities with and submit required reports through the Environmental Sustainability Coordinator or equivalent position. (g) The Contractor shall prepare and submit...

Discrete-time model reduction in limited frequency ranges

NASA Technical Reports Server (NTRS)

Horta, Lucas G.; Juang, Jer-Nan; Longman, Richard W.

1991-01-01

A mathematical formulation for model reduction of discrete time systems such that the reduced order model represents the system in a particular frequency range is discussed. The algorithm transforms the full order system into balanced coordinates using frequency weighted discrete controllability and observability grammians. In this form a criterion is derived to guide truncation of states based on their contribution to the frequency range of interest. Minimization of the criterion is accomplished without need for numerical optimization. Balancing requires the computation of discrete frequency weighted grammians. Close form solutions for the computation of frequency weighted grammians are developed. Numerical examples are discussed to demonstrate the algorithm.

Testing Bell's inequality with cosmic photons: closing the setting-independence loophole.

PubMed

Gallicchio, Jason; Friedman, Andrew S; Kaiser, David I

2014-03-21

We propose a practical scheme to use photons from causally disconnected cosmic sources to set the detectors in an experimental test of Bell's inequality. In current experiments, with settings determined by quantum random number generators, only a small amount of correlation between detector settings and local hidden variables, established less than a millisecond before each experiment, would suffice to mimic the predictions of quantum mechanics. By setting the detectors using pairs of quasars or patches of the cosmic microwave background, observed violations of Bell's inequality would require any such coordination to have existed for billions of years-an improvement of 20 orders of magnitude.

Making the Link. Coordinating Economic Development and Employment and Training. State Governments. Regional Councils. Local Economic Development Agencies.

ERIC Educational Resources Information Center

National Alliance of Business, Inc., Washington, DC.

This document consists of three closely related reports, dealing with "State Governments", "Regional Councils", and "Local Econcomic Development Agencies", respectively, together with a fourth document, a preceding overview. These documents draw from results of a project to identify successful approaches to coordinating economic development and…

Weak coordination among petiole, leaf, vein, and gas-exchange traits across 41 Australian angiosperm species and its possible implications

USDA-ARS?s Scientific Manuscript database

Background and Aims Close coordination between leaf gas exchange and maximal hydraulic supply has been reported across diverse plant life-forms. However, recent reports suggest that this relationship may become weak or break down completely within the angiosperms. Methods To examine this possi...

Correlation between mobility assessed by the Modified Rivermead Mobility Index and physical function in stroke patients

PubMed Central

Park, Gi-Tae; Kim, Mihyun

2016-01-01

[Purpose] The purpose of this study was to investigate the relationship between mobility assessed by the Modified Rivermead Mobility Index and variables associated with physical function in stroke patients. [Subjects and Methods] One hundred stroke patients (35 males and 65 females; age 58.60 ± 13.91 years) participated in this study. Modified Rivermead Mobility Index, muscle strength (manual muscle test), muscle tone (Modified Ashworth Scale), range of motion of lower extremity, sensory function (light touch and proprioception tests), and coordination (heel to shin and lower-extremity motor coordination tests) were assessed. [Results] The Modified Rivermead Mobility Index was correlated with all the physical function variables assessed, except the degree of knee extension. In addition, stepwise linear regression analysis revealed that coordination (heel to shin test) was the explanatory variable closely associated with mobility in stroke patients. [Conclusion] The Modified Rivermead Mobility Index score was significantly correlated with all the physical function variables. Coordination (heel to shin test) was closely related to mobility function. These results may be useful in developing rehabilitation programs for stroke patients. PMID:27630440

Flexible Residential Smart Grid Simulation Framework

NASA Astrophysics Data System (ADS)

Xiang, Wang

Different scheduling and coordination algorithms controlling household appliances' operations can potentially lead to energy consumption reduction and/or load balancing in conjunction with different electricity pricing methods used in smart grid programs. In order to easily implement different algorithms and evaluate their efficiency against other ideas, a flexible simulation framework is desirable in both research and business fields. However, such a platform is currently lacking or underdeveloped. In this thesis, we provide a simulation framework to focus on demand side residential energy consumption coordination in response to different pricing methods. This simulation framework, equipped with an appliance consumption library using realistic values, aims to closely represent the average usage of different types of appliances. The simulation results of traditional usage yield close matching values compared to surveyed real life consumption records. Several sample coordination algorithms, pricing schemes, and communication scenarios are also implemented to illustrate the use of the simulation framework.

Symplectic integration of closed chain rigid body dynamics with internal coordinate equations of motion

NASA Astrophysics Data System (ADS)

Mazur, Alexey K.

1999-07-01

Internal coordinate molecular dynamics (ICMD) is a recent efficient method for modeling polymer molecules which treats them as chains of rigid bodies rather than ensembles of point particles as in Cartesian MD. Unfortunately, it is readily applicable only to linear or tree topologies without closed flexible loops. Important examples violating this condition are sugar rings of nucleic acids, proline residues in proteins, and also disulfide bridges. This paper presents the first complete numerical solution of the chain closure problem within the context of ICMD. The method combines natural implicit fixation of bond lengths and bond angles by the choice of internal coordinates with explicit constraints similar to Cartesian dynamics used to maintain the chain closure. It is affordable for large molecules and makes possible 3-5 times faster dynamics simulations of molecular systems with flexible rings, including important biological objects like nucleic acids and disulfide-bonded proteins.

Relative position coordinated control for spacecraft formation flying with communication delays

NASA Astrophysics Data System (ADS)

Ran, Dechao; Chen, Xiaoqian; Misra, Arun K.; Xiao, Bing

2017-08-01

This study addresses a relative position coordinated control problem for spacecraft formation flying subject to directed communication topology. Two different kinds of communication delay cases, including time-varying delays and arbitrarily bounded delays are investigated. Using the backstepping control technique, two virtual velocity control inputs are firstly designed to achieve coordinated position tracking for the kinematic subsystem. Furthermore, a hyperbolic tangent function is introduced to guarantee the boundedness of the virtual controller. Then, a finite-time control algorithm is designed for the dynamic subsystem. It can guarantee that the virtual velocity can be followed by the real velocity after finite time. It is theoretically proved that the proposed control scheme can asymptotically stabilize the closed-loop system. Numerical simulations are further presented that not only highlight closed-loop performance benefiting from the proposed control scheme, but also illustrate its superiority in comparison with conventional formation control schemes.

Campaigning for College

ERIC Educational Resources Information Center

Roach, Ronald

2007-01-01

This article describes how Texas' Closing the Gaps initiative pays close attention to the demographics of its growing minority communities. West Texas A&M administrators created the University Success Academy (USA) in 2004, which was largely funded through the Texas Higher Education Coordinating Board's First Generation College Student (FGCS)…

Dynamical modelling of coordinated multiple robot systems

NASA Technical Reports Server (NTRS)

Hayati, Samad

1987-01-01

The state of the art in the modeling of the dynamics of coordinated multiple robot manipulators is summarized and various problems related to this subject are discussed. It is recognized that dynamics modeling is a component used in the design of controllers for multiple cooperating robots. As such, the discussion addresses some problems related to the control of multiple robots. The techniques used to date in the modeling of closed kinematic chains are summarized. Various efforts made to date for the control of coordinated multiple manipulators is summarized.

Conformational Activation of Argonaute by Distinct yet Coordinated Actions of the Hsp70 and Hsp90 Chaperone Systems.

PubMed

Tsuboyama, Kotaro; Tadakuma, Hisashi; Tomari, Yukihide

2018-05-17

Loading of small RNAs into Argonaute, the core protein in RNA silencing, requires the Hsp70/Hsp90 chaperone machinery. This machinery also activates many other clients, including steroid hormone receptors and kinases, but how their structures change during chaperone-dependent activation remains unclear. Here, we utilized single-molecule Förster resonance energy transfer (smFRET) to probe the conformational changes of Drosophila Ago2 mediated by the chaperone machinery. We found that empty Ago2 exists in various closed conformations. The Hsp70 system (Hsp40 and Hsp70) and the Hsp90 system (Hop, Hsp90, and p23) together render Ago2 into an open, active form. The Hsp70 system, but not the Hsp90 system alone, is sufficient for Ago2 to partially populate the open form. Instead, the Hsp90 system is required to extend the dwell time of Ago2 in the open state, which must be transiently primed by the Hsp70 system. Our data uncover distinct and coordinated actions of the chaperone machinery, where the Hsp70 system expands the structural ensembles of Ago2 and the Hsp90 system captures and stabilizes the active form. Copyright © 2018 Elsevier Inc. All rights reserved.

MoleCoolQt – a molecule viewer for charge-density research

PubMed Central

Hübschle, Christian B.; Dittrich, Birger

2011-01-01

MoleCoolQt is a molecule viewer for charge-density research. Features include the visualization of local atomic coordinate systems in multipole refinements based on the Hansen and Coppens formalism as implemented, for example, in the XD suite. Residual peaks and holes from XDfft are translated so that they appear close to the nearest atom of the asymmetric unit. Critical points from a topological analysis of the charge density can also be visualized. As in the program MolIso, color-mapped isosurfaces can be generated with a simple interface. Apart from its visualization features the program interactively helps in assigning local atomic coordinate systems and local symmetry, which can be automatically detected and altered. Dummy atoms – as sometimes required for local atomic coordinate systems – are calculated on demand; XD system files are updated after changes. When using the invariom database, potential scattering factor assignment problems can be resolved by the use of an interactive dialog. The following file formats are supported: XD, MoPro, SHELX, GAUSSIAN (com, FChk, cube), CIF and PDB. MoleCoolQt is written in C++ using the Qt4 library, has a user-friendly graphical user interface, and is available for several flavors of Linux, Windows and MacOS. PMID:22477783

Intelligent vehicle safety control strategy in various driving situations

NASA Astrophysics Data System (ADS)

Moon, Seungwuk; Cho, Wanki; Yi, Kyongsu

2010-12-01

This paper describes a safety control strategy for intelligent vehicles with the objective of optimally coordinating the throttle, brake, and active front steering actuator inputs to obtain both lateral stability and longitudinal safety. The control system consists of a supervisor, control algorithms, and a coordinator. From the measurement and estimation signals, the supervisor determines the active control modes among normal driving, longitudinal safety, lateral stability, and integrated safety control mode. The control algorithms consist of longitudinal and lateral stability controllers. The longitudinal controller is designed to improve the driver's comfort during normal, safe-driving situations, and to avoid rear-end collision in vehicle-following situations. The lateral stability controller is designed to obtain the required manoeuvrability and to limit the vehicle body's side-slip angle. To obtain both longitudinal safety and lateral stability control in various driving situations, the coordinator optimally determines the throttle, brake, and active front steering inputs based on the current status of the subject vehicle. Closed-loop simulations with the driver-vehicle-controller system are conducted to investigate the performance of the proposed control strategy. From these simulation results, it is shown that the proposed control algorithm assists the driver in combined severe braking/large steering manoeuvring so that the driver can maintain good manoeuvrability and prevent the vehicle from crashing in vehicle-following situations.

Vehicle coordinated transportation dispatching model base on multiple crisis locations

NASA Astrophysics Data System (ADS)

Tian, Ran; Li, Shanwei; Yang, Guoying

2018-05-01

Many disastrous events are often caused after unconventional emergencies occur, and the requirements of disasters are often different. It is difficult for a single emergency resource center to satisfy such requirements at the same time. Therefore, how to coordinate the emergency resources stored by multiple emergency resource centers to various disaster sites requires the coordinated transportation of emergency vehicles. In this paper, according to the problem of emergency logistics coordination scheduling, based on the related constraints of emergency logistics transportation, an emergency resource scheduling model based on multiple disasters is established.

Potential energy surface interpolation with neural networks for instanton rate calculations

NASA Astrophysics Data System (ADS)

Cooper, April M.; Hallmen, Philipp P.; Kästner, Johannes

2018-03-01

Artificial neural networks are used to fit a potential energy surface (PES). We demonstrate the benefits of using not only energies but also their first and second derivatives as training data for the neural network. This ensures smooth and accurate Hessian surfaces, which are required for rate constant calculations using instanton theory. Our aim was a local, accurate fit rather than a global PES because instanton theory requires information on the potential only in the close vicinity of the main tunneling path. Elongations along vibrational normal modes at the transition state are used as coordinates for the neural network. The method is applied to the hydrogen abstraction reaction from methanol, calculated on a coupled-cluster level of theory. The reaction is essential in astrochemistry to explain the deuteration of methanol in the interstellar medium.

World-wide precision airports for SVS

NASA Astrophysics Data System (ADS)

Schiefele, Jens; Lugsch, Bill; Launer, Marc; Baca, Diana

2004-08-01

Future cockpit and aviation applications require high quality airport databases. Accuracy, resolution, integrity, completeness, traceability, and timeliness [1] are key requirements. For most aviation applications, attributed vector databases are needed. The geometry is based on points, lines, and closed polygons. To document the needs for aviation industry RTCA and EUROCAE developed in a joint committee, the DO-272/ED-99 document. It states industry needs for data features, attributes, coding, and capture rules for Airport Mapping Databases (AMDB). This paper describes the technical approach Jeppesen has taken to generate a world-wide set of three-hundred AMDB airports. All AMDB airports are DO-200A/ED-76 [1] and DO-272/ED-99 [2] compliant. Jeppesen airports have a 5m (CE90) accuracy and an 10-3 integrity. World-wide all AMDB data is delivered in WGS84 coordinates. Jeppesen continually updates the databases.

Organizational Factors Associated With Perceived Quality of Patient Care in Closed Intensive Care Units.

PubMed

McIntosh, Nathalie; Oppel, Eva; Mohr, David; Meterko, Mark

2017-09-01

Improving patient care quality in intensive care units is increasingly important as intensive care unit services account for a growing proportion of hospital services. Organizational factors associated with quality of patient care in such units have been identified; however, most were examined in isolation, making it difficult to assess the relative importance of each. Furthermore, though most intensive care units now use a closed model, little research has been done in this specific context. To examine the relative importance of organizational factors associated with patient care quality in closed intensive care units. In a national exploratory, cross-sectional study focused on intensive care units at US Veterans Health Administration acute care hospitals, unit directors were surveyed about nurse and physician staffing, work resources and training, patient care coordination, rounding, and perceptions of patient care quality. Administrative records yielded data on patient volume and facility teaching status. Descriptive statistics, bivariate analyses, and regression modeling were used for data analysis. Sixty-nine completed surveys from directors of closed intensive care units were returned. Regression model results showed that better patient care coordination (β = 0.43; P = .01) and having adequate work resources (β = 0.26; P = .02) were significantly associated with higher levels of patient care quality in such units ( R 2 = 0.22). Augmenting work resources and/or focusing limited hospital resources on improving patient care coordination may be the most productive ways to improve patient care quality in closed intensive care units. ©2017 American Association of Critical-Care Nurses.

Field testing and implementation of dilemma zone protection and signal coordination at closely-spaced high-speed intersections : final report, May 19, 2005.

DOT National Transportation Integrated Search

2005-05-01

The report presents the details of a study carried out to test and implement a dilemma zone protection technique at three high-speed closely-spaced intersections on Roosevelt Blvd in Middletown, Ohio.

Annual Technical Report, Materials Research Laboratory, 1 July 1984 - 30 June 1986.

DTIC Science & Technology

1986-06-30

4 -’ Section 2 -Inorganic Glasses , Introduction ....... ........... ........................... 54 Research Results...Inorganic Glasses (coordinated by W. M. Risen, Jr.) Surfaces (coordinated by P. J. Estrup). In addition, MRL supported thrce New Initiatives: Physical...on a series of closely related " phenomena in two-phase polycrystalline materials, single crystals and metallic glasses . Although these research

Facilitating Teamwork in Adolescent and Young Adult Oncology

PubMed Central

Macpherson, Catherine Fiona; Smith, Ashley W.; Block, Rebecca G.; Keyton, Joann

2016-01-01

A case of a young adult patient in the days immediately after a cancer diagnosis illustrates the critical importance of three interrelated core coordinating mechanisms—closed-loop communication, shared mental models, and mutual trust—of teamwork in an adolescent and young adult multidisciplinary oncology team. The case illustrates both the opportunities to increase team member coordination and the problems that can occur when coordination breaks down. A model for teamwork is presented, which highlights the relationships among these coordinating mechanisms and demonstrates how balance among them works to optimize team function and patient care. Implications for clinical practice and research suggested by the case are presented. PMID:27624944

How Moving Together Brings Us Together: When Coordinated Rhythmic Movement Affects Cooperation

PubMed Central

Cross, Liam; Wilson, Andrew D.; Golonka, Sabrina

2016-01-01

Although it is well established that rhythmically coordinating with a social partner can increase cooperation, it is as yet unclear when and why intentional coordination has such effects. We distinguish three dimensions along which explanations might vary. First, pro-social effects might require in-phase synchrony or simply coordination. Second, the effects of rhythmic movements on cooperation might be direct or mediated by an intervening variable. Third, the pro-social effects might occur in proportion to the quality of the coordination, or occur once some threshold amount of coordination has occurred. We report an experiment and two follow-ups which sought to identify which classes of models are required to account for the positive effects of coordinated rhythmic movement on cooperation. Across the studies, we found evidence (1) that coordination, and not just synchrony, can have pro-social consequences (so long as the social nature of the task is perceived), (2) that the effects of intentional coordination are direct, not mediated, and (3) that the degree of the coordination did not predict the degree of cooperation. The fact of inter-personal coordination (moving together in time and in a social context) is all that's required for pro-social effects. We suggest that future research should use the kind of carefully controllable experimental task used here to continue to develop explanations for when and why coordination affects pro-social behaviors. PMID:28066301

Field testing and implementation of dilemma zone protection and signal coordination at closely-spaced high-speed intersections : executive summary report.

DOT National Transportation Integrated Search

2005-05-01

The area close to a signalized intersection, : called the dilemma zone, poses a high accident : potential for the driver in stopping safely during the : yellow interval or in proceeding through the : intersection before the beginning of red. Generall...

76 FR 35227 - National Center for Complementary & Alternative Medicine; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-16

... Complementary & Alternative Medicine; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Alternative Medicine Special Emphasis Panel, NIH-HMO Collaboratory Coordinating Center (U54). Date: July 14... Scientific Review, National Center for Complementary, and Alternative Medicine, NIH, 6707 Democracy Blvd...

77 FR 31862 - National Center for Complementary & Alternative Medicine; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-30

... Complementary & Alternative Medicine; Notice of Closed Meetings Pursuant to section 10(d) of the Federal... Alternative Medicine Special Emphasis Panel; HCS Collaboratory Coordinating Center (U54). Date: July 9, 2012... Scientific Review, National Center for Complementary and Alternative Medicine, NIH, 6707 Democracy Blvd...

Telerobotic control of a mobile coordinated robotic server. M.S. Thesis Annual Technical Report

NASA Technical Reports Server (NTRS)

Lee, Gordon

1993-01-01

The annual report on telerobotic control of a mobile coordinated robotic server is presented. The goal of this effort is to develop advanced control methods for flexible space manipulator systems. As such, an adaptive fuzzy logic controller was developed in which model structure as well as parameter constraints are not required for compensation. The work builds upon previous work on fuzzy logic controllers. Fuzzy logic controllers have been growing in importance in the field of automatic feedback control. Hardware controllers using fuzzy logic have become available as an alternative to the traditional PID controllers. Software has also been introduced to aid in the development of fuzzy logic rule-bases. The advantages of using fuzzy logic controllers include the ability to merge the experience and intuition of expert operators into the rule-base and that a model of the system is not required to construct the controller. A drawback of the classical fuzzy logic controller, however, is the many parameters needed to be turned off-line prior to application in the closed-loop. In this report, an adaptive fuzzy logic controller is developed requiring no system model or model structure. The rule-base is defined to approximate a state-feedback controller while a second fuzzy logic algorithm varies, on-line, parameters of the defining controller. Results indicate the approach is viable for on-line adaptive control of systems when the model is too complex or uncertain for application of other more classical control techniques.

Geosynchronous Patrol Orbit for Space Situational Awareness

NASA Astrophysics Data System (ADS)

Thompson, B.; Kelecy, T.; Kubancik, T.; Flora, T.; Chylla, M.; Rose, D.

Applying eccentricity to a geosynchronous orbit produces both longitudinal and radial motion when viewed in Earth-fixed coordinates. An interesting family of orbits emerges, useful for “neighborhood patrol” space situational awareness and other missions. The basic result is a periodic (daily), quasielliptical, closed path around a fixed region of the geosynchronous (geo) orbit belt, keeping a sensor spacecraft in relatively close vicinity to designated geo objects. The motion is similar, in some regards, to the relative motion that may be encountered during spacecraft proximity operations, but on a much larger scale. The patrol orbit does not occupy a fixed slot in the geo belt, and the east-west motion can be combined with north-south motion caused by orbital inclination, leading to even greater versatility. Some practical uses of the geo patrol orbit include space surveillance (including catalog maintenance), and general space situational awareness. The patrol orbit offers improved, diverse observation geometry for angles-only sensors, resulting in faster, more accurate orbit determination compared to simple inclined geo orbits. In this paper, we analyze the requirements for putting a spacecraft in a patrol orbit, the unique station keeping requirements to compensate for perturbations, repositioning the patrol orbit to a different location along the geo belt, maneuvering into, around, and out of the volume for proximity operations with objects within the volume, and safe end-of-life disposal requirements.

An Expanded Theoretical Framework of Care Coordination Across Transitions in Care Settings.

PubMed

Radwin, Laurel E; Castonguay, Denise; Keenan, Carolyn B; Hermann, Cherice

2016-01-01

For many patients, high-quality, patient-centered, and cost-effective health care requires coordination among multiple clinicians and settings. Ensuring optimal care coordination requires a clear understanding of how clinician activities and continuity during transitions affect patient-centeredness and quality outcomes. This article describes an expanded theoretical framework to better understand care coordination. The framework provides clear articulation of concepts. Examples are provided of ways to measure the concepts.

Architecture of the nitric-oxide synthase holoenzyme reveals large conformational changes and a calmodulin-driven release of the FMN domain.

PubMed

Yokom, Adam L; Morishima, Yoshihiro; Lau, Miranda; Su, Min; Glukhova, Alisa; Osawa, Yoichi; Southworth, Daniel R

2014-06-13

Nitric-oxide synthase (NOS) is required in mammals to generate NO for regulating blood pressure, synaptic response, and immune defense. NOS is a large homodimer with well characterized reductase and oxygenase domains that coordinate a multistep, interdomain electron transfer mechanism to oxidize l-arginine and generate NO. Ca(2+)-calmodulin (CaM) binds between the reductase and oxygenase domains to activate NO synthesis. Although NOS has long been proposed to adopt distinct conformations that alternate between interflavin and FMN-heme electron transfer steps, structures of the holoenzyme have remained elusive and the CaM-bound arrangement is unknown. Here we have applied single particle electron microscopy (EM) methods to characterize the full-length of the neuronal isoform (nNOS) complex and determine the structural mechanism of CaM activation. We have identified that nNOS adopts an ensemble of open and closed conformational states and that CaM binding induces a dramatic rearrangement of the reductase domain. Our three-dimensional reconstruction of the intact nNOS-CaM complex reveals a closed conformation and a cross-monomer arrangement with the FMN domain rotated away from the NADPH-FAD center, toward the oxygenase dimer. This work captures, for the first time, the reductase-oxygenase structural arrangement and the CaM-dependent release of the FMN domain that coordinates to drive electron transfer across the domains during catalysis. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

Quality control and improvement of cancer care: what is needed? 4th European Roundtable Meeting (ERTM) May 5th, 2017, Berlin, Germany.

PubMed

Ortmann, Olaf; Helbig, Ulrike; Torode, Julie; Schreck, Stefan; Karjalainen, Sakari; Bettio, Manola; Ringborg, Ulrik; Klinkhammer-Schalke, Monika; Bray, Freddy

2018-06-01

National Cancer Control Plans (NCCPs) often describe structural requirements for high quality cancer care. During the fourth European Roundtable Meeting (ERTM) participants shared learnings from their own national setting to formulate best practice in optimizing communication strategies between parties involved in clinical cancer registries, cancer centers and guideline groups. A decentralized model of data collection close to the patient and caregiver enhances timely completion and the quality of the data captured. Nevertheless, central coordination is necessary to define datasets, indicators, standard settings, education, training and quality control to maintain standards across the network. In particular, interaction of parties in cancer care network has to be established and maintained on a regular basis. After establishing the structural requirements of cancer care networks, communication between the different components and parties is required to analyze outcome data, provide regular reporting to all and develop strategies for continuous improvement of quality across the network.

Spontaneous Intracranial Hypotension: A Review and Introduction of an Algorithm For Management.

PubMed

Davidson, Benjamin; Nassiri, Farshad; Mansouri, Alireza; Badhiwala, Jetan H; Witiw, Christopher D; Shamji, Mohammed F; Peng, Philip W; Farb, Richard I; Bernstein, Mark

2017-05-01

Spontaneous intracranial hypotension (SIH) is a condition of low cerebrospinal fluid volume and pressure caused by a leak of cerebrospinal fluid through a dural defect. Diagnosis and management can be difficult, often requiring coordination between multiple disciplines for myelography, blood patching, and possible surgical repair. Patients should be monitored closely, because they can deteriorate into a coma or even death. There are no widely accepted guidelines for the management of SIH. We review the existing SIH literature, illustrate management challenges via a case review, and propose an algorithm developed by neurosurgeons, radiologists, and anesthesiologists intended to simplify and streamline the management of SIH. Copyright © 2017 Elsevier Inc. All rights reserved.

Surgical management of enterocutaneous fistula.

PubMed

Lee, Suk-Hwan

2012-01-01

Enterocutaneous (EC) fistula is an abnormal connection between the gastrointestinal (GI) tract and skin. The majority of EC fistulas result from surgery. About one third of fistulas close spontaneously with medical treatment and radiologic interventions. Surgical treatment should be reserved for use after sufficient time has passed from the previous laparotomy to allow lysis of the fibrous adhesion using full nutritional and medical treatment and until a complete understanding of the anatomy of the fistula has been achieved. The successful management of GI fistula requires a multi-disciplinary team approach including a gastroenterologist, interventional radiologist, enterostomal therapist, dietician, social worker and surgeons. With this coordinated approach, EC fistula can be controlled with acceptable morbidity and mortality.

Surgical Management of Enterocutaneous Fistula

PubMed Central

2012-01-01

Enterocutaneous (EC) fistula is an abnormal connection between the gastrointestinal (GI) tract and skin. The majority of EC fistulas result from surgery. About one third of fistulas close spontaneously with medical treatment and radiologic interventions. Surgical treatment should be reserved for use after sufficient time has passed from the previous laparotomy to allow lysis of the fibrous adhesion using full nutritional and medical treatment and until a complete understanding of the anatomy of the fistula has been achieved. The successful management of GI fistula requires a multi-disciplinary team approach including a gastroenterologist, interventional radiologist, enterostomal therapist, dietician, social worker and surgeons. With this coordinated approach, EC fistula can be controlled with acceptable morbidity and mortality. PMID:22563283

New Approaches to HSCT Multidisciplinary Design and Optimization

NASA Technical Reports Server (NTRS)

Schrage, Daniel P.; Craig, James I.; Fulton, Robert E.; Mistree, Farrokh

1999-01-01

New approaches to MDO have been developed and demonstrated during this project on a particularly challenging aeronautics problem- HSCT Aeroelastic Wing Design. To tackle this problem required the integration of resources and collaboration from three Georgia Tech laboratories: ASDL, SDL, and PPRL, along with close coordination and participation from industry. Its success can also be contributed to the close interaction and involvement of fellows from the NASA Multidisciplinary Analysis and Optimization (MAO) program, which was going on in parallel, and provided additional resources to work the very complex, multidisciplinary problem, along with the methods being developed. The development of the Integrated Design Engineering Simulator (IDES) and its initial demonstration is a necessary first step in transitioning the methods and tools developed to larger industrial sized problems of interest. It also provides a framework for the implementation and demonstration of the methodology. Attachment: Appendix A - List of publications. Appendix B - Year 1 report. Appendix C - Year 2 report. Appendix D - Year 3 report. Appendix E - accompanying CDROM.

Theoretical constraints in the design of multivariable control systems

NASA Technical Reports Server (NTRS)

Rynaski, E. G.; Mook, D. J.

1993-01-01

The theoretical constraints inherent in the design of multivariable control systems were defined and investigated. These constraints are manifested by the system transmission zeros that limit or bound the areas in which closed loop poles and individual transfer function zeros may be placed. These constraints were investigated primarily in the context of system decoupling or non-interaction. It was proven that decoupling requires the placement of closed loop poles at the system transmission zeros. Therefore, the system transmission zeros must be minimum phase to guarantee a stable decoupled system. Once decoupling has been accomplished, the remaining part of the system exhibits transmission zeros at infinity, so nearly complete design freedom is possible in terms of placing both poles and zeros of individual closed loop transfer functions. A general, dynamic inversion model following system architecture was developed that encompasses both the implicit and explicit configuration. Robustness properties are developed along with other attributes of this type of system. Finally, a direct design is developed for the longitudinal-vertical degrees of freedom of aircraft motion to show how a direct lift flap can be used to improve the pitch-heave maneuvering coordination for enhanced flying qualities.

Cooperative functions of duetting behaviour in tropical wrens

NASA Astrophysics Data System (ADS)

Kovach, Kristin Ashley

Vocal duets occur when two breeding partners coordinate their songs into a joint display. Duetting serves functions both within and between pairs, and functionality is often context dependent. I explore the function of temporal coordination of male and female songs into duets, testing the hypothesis that coordinated duets are more threatening territorial signals than poorly coordinated duets or solos in three closely related species of wren. Results indicate that birds respond with similar levels of physical aggression to all three levels of coordination; however, they sing more duets in response to both categories of duets. I also explore duets and other vocalizations as they are used during breeding, testing the hypothesis that duets play a role in coordinating nest visitation. Contrary to my predictions, the birds sang the most duets during the incubation stage. My results suggest that duets are used for both territory defence and communication at the nest.

76 FR 45585 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-29

... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel, Teddy Coordinating Center. Date: August... Nutrition Research; 93.849, Kidney Diseases, Urology and Hematology Research, National Institutes of Health...

77 FR 38075 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-26

... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; Type 1 Diabetes Mouse Resource. Date... and Kidney Diseases Special Emphasis Panel; IBD Genetics Consortium Data Coordinating Center. Date...

Automated and Cooperative Vehicle Merging at Highway On-Ramps

DOE PAGES

Rios-Torres, Jackeline; Malikopoulos, Andreas A.

2016-08-05

Recognition of necessities of connected and automated vehicles (CAVs) is gaining momentum. CAVs can improve both transportation network efficiency and safety through control algorithms that can harmonically use all existing information to coordinate the vehicles. This paper addresses the problem of optimally coordinating CAVs at merging roadways to achieve smooth traffic flow without stop-and-go driving. Here we present an optimization framework and an analytical closed-form solution that allows online coordination of vehicles at merging zones. The effectiveness of the efficiency of the proposed solution is validated through a simulation, and it is shown that coordination of vehicles can significantly reducemore » both fuel consumption and travel time.« less

Movement Forms: A Graph-Dynamic Perspective

PubMed Central

Saltzman, Elliot; Holt, Ken

2014-01-01

The focus of this paper is on characterizing the physical movement forms (e.g., walk, crawl, roll, etc.) that can be used to actualize abstract, functionally-specified behavioral goals (e.g., locomotion). Emphasis is placed on how such forms are distinguished from one another, in part, by the set of topological patterns of physical contact between agent and environment (i.e., the set of physical graphs associated with each form) and the transitions among these patterns displayed over the course of performance (i.e., the form’s physical graph dynamics). Crucial in this regard is the creation and dissolution of loops in these graphs, which can be related to the distinction between open and closed kinematic chains. Formal similarities are described within the theoretical framework of task-dynamics between physically-closed kinematic chains (physical loops) that are created during various movement forms and functionally-closed kinematic chains (functional loops) that are associated with task-space control of end-effectors; it is argued that both types of loop must be flexibly incorporated into the coordinative structures that govern skilled action. Final speculation is focused on the role of graphs and their dynamics, not only in processes of coordination and control for individual agents, but also in processes of inter-agent coordination and the coupling of agents with (non-sentient) environmental objects. PMID:24910507

Movement Forms: A Graph-Dynamic Perspective.

PubMed

Saltzman, Elliot; Holt, Ken

2014-01-01

The focus of this paper is on characterizing the physical movement forms (e.g., walk, crawl, roll, etc.) that can be used to actualize abstract, functionally-specified behavioral goals (e.g., locomotion). Emphasis is placed on how such forms are distinguished from one another, in part, by the set of topological patterns of physical contact between agent and environment (i.e., the set of physical graphs associated with each form) and the transitions among these patterns displayed over the course of performance (i.e., the form's physical graph dynamics ). Crucial in this regard is the creation and dissolution of loops in these graphs, which can be related to the distinction between open and closed kinematic chains. Formal similarities are described within the theoretical framework of task-dynamics between physically-closed kinematic chains (physical loops) that are created during various movement forms and functionally-closed kinematic chains (functional loops) that are associated with task-space control of end-effectors; it is argued that both types of loop must be flexibly incorporated into the coordinative structures that govern skilled action. Final speculation is focused on the role of graphs and their dynamics, not only in processes of coordination and control for individual agents, but also in processes of inter-agent coordination and the coupling of agents with (non-sentient) environmental objects.

Recycling Pricing and Coordination of WEEE Dual-Channel Closed-Loop Supply Chain Considering Consumers' Bargaining.

PubMed

Zhu, Xiaodong; Wang, Jing; Tang, Juan

2017-12-15

Environmentally friendly handling and efficient recycling of waste electrical on Waste Electrical and Electronic Equipment (WEEE) have grown to be a global social problem. As holders of WEEE, consumers have a significant effect on the recycling process. A consideration of and attention to the influence of consumer behavior in the recycling process can help achieve more effective recycling of WEEE. In this paper, we built a dual-channel closed-loop supply chain model composed of manufacturers, retailers, and network recycling platforms. Based on the influence of customer bargaining behavior, we studied several different scenarios of centralized decision-making, decentralized decision-making, and contract coordination, using the Stackelberg game theory. The results show that retailers and network recycling platforms will reduce the direct recovery prices to maintain their own profit when considering the impact of consumer bargaining behavior, while remanufacturers will improve the transfer payment price for surrendering part of the profit under revenue and the expense sharing contract. Using this contract, we can achieve supply chain coordination and eliminate the effect of consumer bargaining behavior on supply chain performance. It can be viewed from the parameter sensitivity analysis that when we select the appropriate sharing coefficient, the closed-loop supply chain can achieve the same system performance under a centralized decision.

Recycling Pricing and Coordination of WEEE Dual-Channel Closed-Loop Supply Chain Considering Consumers’ Bargaining

PubMed Central

Zhu, Xiaodong; Wang, Jing; Tang, Juan

2017-01-01

Environmentally friendly handling and efficient recycling of waste electrical on Waste Electrical and Electronic Equipment (WEEE) have grown to be a global social problem. As holders of WEEE, consumers have a significant effect on the recycling process. A consideration of and attention to the influence of consumer behavior in the recycling process can help achieve more effective recycling of WEEE. In this paper, we built a dual-channel closed-loop supply chain model composed of manufacturers, retailers, and network recycling platforms. Based on the influence of customer bargaining behavior, we studied several different scenarios of centralized decision-making, decentralized decision-making, and contract coordination, using the Stackelberg game theory. The results show that retailers and network recycling platforms will reduce the direct recovery prices to maintain their own profit when considering the impact of consumer bargaining behavior, while remanufacturers will improve the transfer payment price for surrendering part of the profit under revenue and the expense sharing contract. Using this contract, we can achieve supply chain coordination and eliminate the effect of consumer bargaining behavior on supply chain performance. It can be viewed from the parameter sensitivity analysis that when we select the appropriate sharing coefficient, the closed-loop supply chain can achieve the same system performance under a centralized decision. PMID:29244778

An application of corelap algoritm to improve the utilization space of the classroom

NASA Astrophysics Data System (ADS)

Sembiring, A. C.; Budiman, I.; Mardhatillah, A.; Tarigan, U. P.; Jawira, A.

2018-04-01

The high demand of the room due to the increasing number of students requires the addition of the room The limited number of rooms, the price of land and the cost of building expensive infrastructure requires effective and efficient use of the space. The facility layout redesign is done using the Computerized Relationship Planning (CORELAP) algorithm based on total closeness rating (TCR). By calculating the square distance between the departments based on the coordinates of the central point of the department. The distance obtained is multiplied by the material current from the From-to chart matrix. The analysis is done by comparing the total distance between the initial layout and the proposed layout and then viewing the activities performed in each room. The results of CORELAP algorithm processing gives an increase of room usage efficiency equal to 14, 98% from previous activity.

An Object-Oriented Graphical User Interface for a Reusable Rocket Engine Intelligent Control System

NASA Technical Reports Server (NTRS)

Litt, Jonathan S.; Musgrave, Jeffrey L.; Guo, Ten-Huei; Paxson, Daniel E.; Wong, Edmond; Saus, Joseph R.; Merrill, Walter C.

1994-01-01

An intelligent control system for reusable rocket engines under development at NASA Lewis Research Center requires a graphical user interface to allow observation of the closed-loop system in operation. The simulation testbed consists of a real-time engine simulation computer, a controls computer, and several auxiliary computers for diagnostics and coordination. The system is set up so that the simulation computer could be replaced by the real engine and the change would be transparent to the control system. Because of the hard real-time requirement of the control computer, putting a graphical user interface on it was not an option. Thus, a separate computer used strictly for the graphical user interface was warranted. An object-oriented LISP-based graphical user interface has been developed on a Texas Instruments Explorer 2+ to indicate the condition of the engine to the observer through plots, animation, interactive graphics, and text.

Masticatory motor patterns in ungulates: a quantitative assessment of jaw-muscle coordination in goats, alpacas and horses.

PubMed

Williams, Susan H; Vinyard, Christopher J; Wall, Christine E; Hylander, William L

2007-04-01

We investigated patterns of jaw-muscle coordination during rhythmic mastication in three species of ungulates displaying the marked transverse jaw movements typical of many large mammalian herbivores. In order to quantify consistent motor patterns during chewing, electromyograms were recorded from the superficial masseter, deep masseter, posterior temporalis and medial pterygoid muscles of goats, alpacas and horses. Timing differences between muscle pairs were evaluated in the context of an evolutionary model of jaw-muscle function. In this model, the closing and food reduction phases of mastication are primarily controlled by two distinct muscle groups, triplet I (balancing-side superficial masseter and medial pterygoid and working-side posterior temporalis) and triplet II (working-side superficial masseter and medial pterygoid and balancing-side posterior temporalis), and the asynchronous activity of the working- and balancing-side deep masseters. The three species differ in the extent to which the jaw muscles are coordinated as triplet I and triplet II. Alpacas, and to a lesser extent, goats, exhibit the triplet pattern whereas horses do not. In contrast, all three species show marked asynchrony of the working-side and balancing-side deep masseters, with jaw closing initiated by the working-side muscle and the balancing-side muscle firing much later during closing. However, goats differ from alpacas and horses in the timing of the balancing-side deep masseter relative to the triplet II muscles. This study highlights interspecific differences in the coordination of jaw muscles to influence transverse jaw movements and the production of bite force in herbivorous ungulates.

Advanced Outage and Control Center: Strategies for Nuclear Plant Outage Work Status Capabilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gregory Weatherby

The research effort is a part of the Light Water Reactor Sustainability (LWRS) Program. LWRS is a research and development program sponsored by the Department of Energy, performed in close collaboration with industry to provide the technical foundations for licensing and managing the long-term, safe and economical operation of current nuclear power plants. The LWRS Program serves to help the US nuclear industry adopt new technologies and engineering solutions that facilitate the continued safe operation of the plants and extension of the current operating licenses. The Outage Control Center (OCC) Pilot Project was directed at carrying out the applied researchmore » for development and pilot of technology designed to enhance safe outage and maintenance operations, improve human performance and reliability, increase overall operational efficiency, and improve plant status control. Plant outage management is a high priority concern for the nuclear industry from cost and safety perspectives. Unfortunately, many of the underlying technologies supporting outage control are the same as those used in the 1980’s. They depend heavily upon large teams of staff, multiple work and coordination locations, and manual administrative actions that require large amounts of paper. Previous work in human reliability analysis suggests that many repetitive tasks, including paper work tasks, may have a failure rate of 1.0E-3 or higher (Gertman, 1996). With between 10,000 and 45,000 subtasks being performed during an outage (Gomes, 1996), the opportunity for human error of some consequence is a realistic concern. Although a number of factors exist that can make these errors recoverable, reducing and effectively coordinating the sheer number of tasks to be performed, particularly those that are error prone, has the potential to enhance outage efficiency and safety. Additionally, outage management requires precise coordination of work groups that do not always share similar objectives. Outage managers are concerned with schedule and cost, union workers are concerned with performing work that is commensurate with their trade, and support functions (safety, quality assurance, and radiological controls, etc.) are concerned with performing the work within the plants controls and procedures. Approaches to outage management should be designed to increase the active participation of work groups and managers in making decisions that closed the gap between competing objectives and the potential for error and process inefficiency.« less

How we developed the GIM clinician-educator mentoring and scholarship program to assist faculty with promotion and scholarly work.

PubMed

Bertram, Amanda; Yeh, Hsin Chieh; Bass, Eric B; Brancati, Frederick; Levine, David; Cofrancesco, Joseph

2015-02-01

Clinician Educators' (CEs) focus on patient care and teaching, yet many academic institutions require dissemination of scholarly work for advancement. This can be difficult for CEs. Our division developed the Clinician-Educator Mentoring and Scholarship Program (CEMSP) in an effort to assist CEs with scholarship, national reputation, recognition, promotion and job satisfaction. The key components are salary-supported director and co-director who coordinate the program and serve as overall mentors and link CEs and senior faculty, and a full-time Senior Research Coordinator to assist with all aspects of scholarship, a close relationship with the General Internal Medicine (GIM) Methods Core provides advanced statistical support. Funding for the program comes from GIM divisional resources. Perceived value was evaluated by assessing the number of manuscripts published, survey of faculty regarding usage and opinion of CEMSP, and a review of faculty promotions. Although impossible to attribute the contributions of an individual component, a program specifically aimed at helping GIM CE faculty publish scholarly projects, increase participation in national organizations and focus on career progression can have a positive impact.

Healthier Students Are Better Learners: High-Quality, Strategically Planned, and Effectively Coordinated School Health Programs Must Be a Fundamental Mission of Schools to Help Close the Achievement Gap

ERIC Educational Resources Information Center

Basch, Charles E.

2011-01-01

Objective: To discuss implications for educational policy and practice relevant to closing the achievement gap based on the literature review and synthesis presented in 7 articles of the October 2011 special issue of the "Journal of School Health". Methods: Implications for closing the achievement gap are drawn from analyses of current literature.…

Generalized Squashing Factors for Covariant Description of Magnetic Connectivity in the Solar Corona

NASA Technical Reports Server (NTRS)

Titov, V. S.

2007-01-01

The study of magnetic connectivity in the solar corona reveals a need to generalize the field line mapping technique to arbitrary geometry of the boundaries and systems of coordinates. Indeed, the global description of the connectivity in the corona requires the use of the photospheric and solar wind boundaries. Both are closed surfaces and therefore do not admit a global regular system of coordinates. At least two overlapping regular systems of coordinates for each of the boundaries are necessary in this case to avoid spherical-pole-like singularities in the coordinates of the footpoints. This implies that the basic characteristic of magnetic connectivity-the squashing degree or factor Q of elemental flux tubes, according to Titov and coworkers-must be rewritten in covariant form. Such a covariant expression of Q is derived in this work. The derived expression is very flexible and highly efficient for describing the global magnetic connectivity in the solar corona. In addition, a general expression for a new characteristic Q1, which defines a squashing of the flux tubes in the directions perpendicular to the field lines, is determined. This new quantity makes it possible to filter out the quasi-separatrix layers whose large values of Q are caused by a projection effect at the field lines nearly touching the photosphere. Thus, the value Q1 provides a much more precise description of the volumetric properties of the magnetic field structure. The difference between Q and Q1 is illustrated by comparing their distributions for two configurations, one of which is the Titov-Demoulin model of a twisted magnetic field.

Promise-based management: the essence of execution.

PubMed

Sull, Donald N; Spinosa, Charles

2007-04-01

Critical initiatives stall for a variety of reasons--employee disengagement, a lack of coordination between functions, complex organizational structures that obscure accountability, and so on. To overcome such obstacles, managers must fundamentally rethink how work gets done. Most of the challenges stem from broken or poorly crafted commitments. That's because every company is, at its heart, a dynamic network of promises made between employees and colleagues, customers, outsourcing partners, or other stakeholders. Executives can overcome many problems in the short-term and foster productive, reliable workforces for the long-term by practicing what the authors call "promise-based management," which involves cultivating and coordinating commitments in a systematic way. Good promises share five qualities: They are public, active, voluntary, explicit, and mission based. To develop and execute an effective promise, the "provider" and the "customer" in the deal should go through three phases of conversation. The first, achieving a meeting of minds, entails exploring the fundamental questions of coordinated effort: What do you mean? Do you understand what I mean? What should I do? What will you do? Who else should we talk to? In the next phase, making it happen, the provider executes on the promise. In the final phase, closing the loop, the customer publicly declares that the provider has either delivered the goods or failed to do so. Leaders must weave and manage their webs of promises with great care-encouraging iterative conversation and making sure commitments are fulfilled reliably. If they do, they can enhance coordination and cooperation among colleagues, build the organizational agility required to seize new business opportunities, and tap employees' entrepreneurial energies.

Is the Unfolding of the Group Discussion Off-Pattern? Improving Coordination Support in Educational Forums Using Mobile Devices

ERIC Educational Resources Information Center

Gerosa, Marco Aurelio; Filippo, Denise; Pimentel, Mariano; Fuks, Hugo; Lucena, Carlos J. P.

2010-01-01

A forum is a valuable tool to foster reflection in an in-depth discussion; however, it forces the course mediator to continually pay close attention in order to coordinate learners' activities. Moreover, monitoring a forum is time consuming given that it is impossible to know in advance when new messages are going to be posted. Additionally, a…

Wounding coordinately induces cell wall protein, cell cycle and pectin methyl esterase genes involved in tuber closing layer and wound periderm development

USDA-ARS?s Scientific Manuscript database

Potato (Solanum tuberosum L.) is the world’s fourth largest food crop and large financial losses are incurred each year from wound and bruise related injuries. However, little is known about the coordinate induction of genes that may be associated with or mark major wound-healing events. In this s...

A computer program for the geometrically nonlinear static and dynamic analysis of arbitrarily loaded shells of revolution, theory and users manual

NASA Technical Reports Server (NTRS)

Ball, R. E.

1972-01-01

A digital computer program known as SATANS (static and transient analysis, nonlinear, shells) for the geometrically nonlinear static and dynamic response of arbitrarily loaded shells of revolution is presented. Instructions for the preparation of the input data cards and other information necessary for the operation of the program are described in detail and two sample problems are included. The governing partial differential equations are based upon Sanders' nonlinear thin shell theory for the conditions of small strains and moderately small rotations. The governing equations are reduced to uncoupled sets of four linear, second order, partial differential equations in the meridional and time coordinates by expanding the dependent variables in a Fourier sine or cosine series in the circumferential coordinate and treating the nonlinear modal coupling terms as pseudo loads. The derivatives with respect to the meridional coordinate are approximated by central finite differences, and the displacement accelerations are approximated by the implicit Houbolt backward difference scheme with a constant time interval. The boundaries of the shell may be closed, free, fixed, or elastically restrained. The program is coded in the FORTRAN 4 language and is dimensioned to allow a maximum of 10 arbitrary Fourier harmonics and a maximum product of the total number of meridional stations and the total number of Fourier harmonics of 200. The program requires 155,000 bytes of core storage.

The role of social attraction and its link with boldness in the collective movements of three-spined sticklebacks.

PubMed

Jolles, Jolle W; Fleetwood-Wilson, Adeline; Nakayama, Shinnosuke; Stumpe, Martin C; Johnstone, Rufus A; Manica, Andrea

2015-01-01

Social animals must time and coordinate their behaviour to ensure the benefits of grouping, resulting in collective movements and the potential emergence of leaders and followers. However, individuals often differ consistently from one another in how they cope with their environment, a phenomenon known as animal personality, which may affect how individuals use coordination rules and requiring them to compromise. Here we tracked the movements of pairs of three-spined sticklebacks, Gasterosteus aculeatus , separated by a transparent partition that allowed them to observe and interact with one another in a context containing cover. Individuals differed consistently in their tendency to approach their partner's compartment during collective movements. The strength of this social attraction was positively correlated with the behavioural coordination between members of a pair but was negatively correlated with an individual's tendency to lead. Social attraction may form part of a broader behavioural syndrome as it was predicted by the boldness of an individual, measured in isolation prior to the observation of pairs, and by the boldness of the partner. We found that bolder fish, and those paired with bolder partners, tended to approach their partner's compartment less closely. These findings provide important insights into the mechanisms that govern the dynamics and functioning of social groups and the emergence and maintenance of consistent behavioural differences.

The role of social attraction and its link with boldness in the collective movements of three-spined sticklebacks

PubMed Central

Jolles, Jolle W.; Fleetwood-Wilson, Adeline; Nakayama, Shinnosuke; Stumpe, Martin C.; Johnstone, Rufus A.; Manica, Andrea

2015-01-01

Social animals must time and coordinate their behaviour to ensure the benefits of grouping, resulting in collective movements and the potential emergence of leaders and followers. However, individuals often differ consistently from one another in how they cope with their environment, a phenomenon known as animal personality, which may affect how individuals use coordination rules and requiring them to compromise. Here we tracked the movements of pairs of three-spined sticklebacks, Gasterosteus aculeatus, separated by a transparent partition that allowed them to observe and interact with one another in a context containing cover. Individuals differed consistently in their tendency to approach their partner's compartment during collective movements. The strength of this social attraction was positively correlated with the behavioural coordination between members of a pair but was negatively correlated with an individual's tendency to lead. Social attraction may form part of a broader behavioural syndrome as it was predicted by the boldness of an individual, measured in isolation prior to the observation of pairs, and by the boldness of the partner. We found that bolder fish, and those paired with bolder partners, tended to approach their partner's compartment less closely. These findings provide important insights into the mechanisms that govern the dynamics and functioning of social groups and the emergence and maintenance of consistent behavioural differences. PMID:25598543

Inadequate interaction between open- and closed-loop postural control in phobic postural vertigo.

PubMed

Wuehr, M; Pradhan, C; Novozhilov, S; Krafczyk, S; Brandt, T; Jahn, K; Schniepp, R

2013-05-01

Phobic postural vertigo (PPV) is characterized by a subjective dizziness and postural imbalance. Changes in postural control strategy may cause the disturbed postural performance in PPV. A better understanding of the mechanisms behind this change in strategy is required to improve the diagnostic tools and therapeutic options for this prevalent disorder. Here we apply stabilogram diffusion analysis (SDA) to examine the characteristics and modes of interaction of open- and closed-loop processes that make up the postural control scheme in PPV. Twenty patients with PPV and 20 age-matched healthy controls were recorded on a stabilometer platform with eyes open and with eyes closed. Spatio-temporal changes of the center of pressure (CoP) displacement were analyzed by means of SDA and complementary CoP amplitude measures. (1) Open-loop control mechanisms in PPV were disturbed because of a higher diffusion activity (p < 0.001). (2) The interaction of open- and closed-loop processes was altered in that the sensory feedback threshold of the system was lowered (p = 0.010). These two changes were comparable to those observed in healthy subjects during more demanding balance conditions such as standing with eyes closed. These data indicate that subjective imbalance in PPV is associated with characteristic changes in the coordination of open- and closed-loop mechanisms of postural control. Patients with PPV use sensory feedback inadequately during undisturbed stance, and this impairs postural performance. These changes are compatible with higher levels of anti-gravity muscle activity and co-contraction during the conscious concentration on control of postural stability.

Time-Coordination Strategies and Control Laws for Multi-Agent Unmanned Systems

NASA Technical Reports Server (NTRS)

Puig-Navarro, Javier; Hovakimyan, Naira; Allen, B. Danette

2017-01-01

Time-critical coordination tools for unmanned systems can be employed to enforce the type of temporal constraints required in terminal control areas, ensure minimum distance requirements among vehicles are satisfied, and successfully perform coordinated missions. In comparison with previous literature, this paper presents an ampler spectrum of coordination and temporal specifications for unmanned systems, and proposes a general control law that can enforce this range of constraints. The constraint classification presented con- siders the nature of the desired arrival window and the permissible coordination errors to define six different types of time-coordination strategies. The resulting decentralized coordination control law allows the vehicles to negotiate their speeds along their paths in response to information exchanged over the communication network. This control law organizes the different members in the fleet hierarchically per their behavior and informational needs as reference agent, leaders, and followers. Examples and simulation results for all the coordination strategies presented demonstrate the applicability and efficacy of the coordination control law for multiple unmanned systems.

48 CFR 809.402 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... consideration in the decision-making process. (c) The D&S Committee will maintain close coordination with the appropriate official through completion of a final debarment or suspension decision. ...

45 CFR 1310.23 - Coordinated transportation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 4 2012-10-01 2012-10-01 false Coordinated transportation. 1310.23 Section 1310... START PROGRAM HEAD START TRANSPORTATION Special Requirements § 1310.23 Coordinated transportation. (a) Each agency providing transportation services must make reasonable efforts to coordinate transportation...

45 CFR 1310.23 - Coordinated transportation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 4 2013-10-01 2013-10-01 false Coordinated transportation. 1310.23 Section 1310... START PROGRAM HEAD START TRANSPORTATION Special Requirements § 1310.23 Coordinated transportation. (a) Each agency providing transportation services must make reasonable efforts to coordinate transportation...

45 CFR 1310.23 - Coordinated transportation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 4 2014-10-01 2014-10-01 false Coordinated transportation. 1310.23 Section 1310... START PROGRAM HEAD START TRANSPORTATION Special Requirements § 1310.23 Coordinated transportation. (a) Each agency providing transportation services must make reasonable efforts to coordinate transportation...

78 FR 73819 - Forest Resource Coordinating Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-09

... DEPARTMENT OF AGRICULTURE Forest Service Forest Resource Coordinating Committee AGENCY: Forest... was required to cancel the October 17-18, 2013 meeting of the Forest Resource Coordinating Committee..., September 17, 2013, Page 57128. FOR FURTHER INFORMATION CONTACT: Maya Solomon, Forest Resource Coordinating...

Team Software Process (TSP) Body of Knowledge (BOK)

DTIC Science & Technology

2010-07-01

styles that correspond stereotypical extremes of group control and coordination, as shown in Figure 5. closed, random, open, and synchronous group ...and confirming the resolutions • managing the design change process and coordinating changes with the configuration control board • reporting...members. 123 | CMU/SEI-2010-TR-020 4. Coaching – Obtain a lead coach and the coaches for each team. 5. Conceptual design – Form a working group of

New coordination features; a bridging pyridine and the forced shortest non-covalent distance between two CO3 2– species† †Electronic supplementary information (ESI) available: Mass Spectrometry and BVS analysis CCDC 996546–996548. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc02491e Click here for additional data file. Click here for additional data file.

PubMed Central

Velasco, V.; Aguilà, D.; Barrios, L. A.; Borilovic, I.; Roubeau, O.; Ribas-Ariño, J.; Fumanal, M.; Teat, S. J.

2015-01-01

The aerobic reaction of the multidentate ligand 2,6-bis-(3-oxo-3-(2-hydroxyphenyl)-propionyl)-pyridine, H4L, with Co(ii) salts in strong basic conditions produces the clusters [Co4(L)2(OH)(py)7]NO3 (1) and [Co8Na4(L)4(OH)2(CO3)2(py)10](BF4)2 (2). Analysis of their structure unveils unusual coordination features including a very rare bridging pyridine ligand or two trapped carbonate anions within one coordination cage, forced to stay at an extremely close distance (d O···O = 1.946 Å). This unprecedented non-bonding proximity represents a meeting point between long covalent interactions and “intermolecular” contacts. These original motifs have been analysed here through DFT calculations, which have yielded interaction energies and the reduced repulsion energy experimented by both CO3 2– anions when located in close proximity inside the coordination cage. PMID:28616127

Terrain Correction on the moving equal area cylindrical map projection of the surface of a reference ellipsoid

NASA Astrophysics Data System (ADS)

Ardalan, A.; Safari, A.; Grafarend, E.

2003-04-01

An operational algorithm for computing the ellipsoidal terrain correction based on application of closed form solution of the Newton integral in terms of Cartesian coordinates in the cylindrical equal area map projected surface of a reference ellipsoid has been developed. As the first step the mapping of the points on the surface of a reference ellipsoid onto the cylindrical equal area map projection of a cylinder tangent to a point on the surface of reference ellipsoid closely studied and the map projection formulas are computed. Ellipsoidal mass elements with various sizes on the surface of the reference ellipsoid is considered and the gravitational potential and the vector of gravitational intensity of these mass elements has been computed via the solution of Newton integral in terms of ellipsoidal coordinates. The geographical cross section areas of the selected ellipsoidal mass elements are transferred into cylindrical equal area map projection and based on the transformed area elements Cartesian mass elements with the same height as that of the ellipsoidal mass elements are constructed. Using the close form solution of the Newton integral in terms of Cartesian coordinates the potential of the Cartesian mass elements are computed and compared with the same results based on the application of the ellipsoidal Newton integral over the ellipsoidal mass elements. The results of the numerical computations show that difference between computed gravitational potential of the ellipsoidal mass elements and Cartesian mass element in the cylindrical equal area map projection is of the order of 1.6 × 10-8m^2/s^2 for a mass element with the cross section size of 10 km × 10 km and the height of 1000 m. For a 1 km × 1 km mass element with the same height, this difference is less than 1.5 × 10-4 m^2}/s^2. The results of the numerical computations indicate that a new method for computing the terrain correction based on the closed form solution of the Newton integral in terms of Cartesian coordinates and with accuracy of ellipsoidal terrain correction has been achieved! In this way one can enjoy the simplicity of the solution of the Newton integral in terms of Cartesian coordinates and at the same time the accuracy of the ellipsoidal terrain correction, which is needed for the modern theory of geoid computations.

Exact Fourier expansion in cylindrical coordinates for the three-dimensional Helmholtz Green function

NASA Astrophysics Data System (ADS)

Conway, John T.; Cohl, Howard S.

2010-06-01

A new method is presented for Fourier decomposition of the Helmholtz Green function in cylindrical coordinates, which is equivalent to obtaining the solution of the Helmholtz equation for a general ring source. The Fourier coefficients of the Green function are split into their half advanced + half retarded and half advanced-half retarded components, and closed form solutions for these components are then obtained in terms of a Horn function and a Kampé de Fériet function respectively. Series solutions for the Fourier coefficients are given in terms of associated Legendre functions, Bessel and Hankel functions and a hypergeometric function. These series are derived either from the closed form 2-dimensional hypergeometric solutions or from an integral representation, or from both. A simple closed form far-field solution for the general Fourier coefficient is derived from the Hankel series. Numerical calculations comparing different methods of calculating the Fourier coefficients are presented. Fourth order ordinary differential equations for the Fourier coefficients are also given and discussed briefly.

Chromosomal Arrangement of Phosphorelay Genes Couples Sporulation and DNA Replication.

PubMed

Narula, Jatin; Kuchina, Anna; Lee, Dong-Yeon D; Fujita, Masaya; Süel, Gürol M; Igoshin, Oleg A

2015-07-16

Genes encoding proteins in a common regulatory network are frequently located close to one another on the chromosome to facilitate co-regulation or couple gene expression to growth rate. Contrasting with these observations, here, we demonstrate a functional role for the arrangement of Bacillus subtilis sporulation network genes on opposite sides of the chromosome. We show that the arrangement of two sporulation network genes, one located close to the origin and the other close to the terminus, leads to a transient gene dosage imbalance during chromosome replication. This imbalance is detected by the sporulation network to produce cell-cycle coordinated pulses of the sporulation master regulator Spo0A∼P. This pulsed response allows cells to decide between sporulation and continued vegetative growth during each cell cycle spent in starvation. The simplicity of this coordination mechanism suggests that it may be widely applicable in a variety of gene regulatory and stress-response settings. VIDEO ABSTRACT. Copyright © 2015 Elsevier Inc. All rights reserved.

Lower Limb Interjoint Postural Coordination One Year after First-Time Lateral Ankle Sprain.

PubMed

Doherty, Cailbhe; Bleakley, Chris; Hertel, Jay; Caulfield, Brian; Ryan, John; Sweeney, Kevin; Patterson, Matthew R; Delahunt, Eamonn

2015-11-01

Longitudinal analyses of participants with a history of lateral ankle sprain are lacking. This investigation combined measures of lower limb interjoint coordination and stabilometry to evaluate static unipedal stance with the eyes open (condition 1) and closed (condition 2) in a group of participants with chronic ankle instability (CAI) compared to lateral ankle sprain "copers" (both recruited 12 months after sustaining an acute first-time lateral ankle sprain) and a group of noninjured controls. Twenty-eight participants with CAI, 42 lateral ankle sprain "copers," and 20 noninjured controls completed three 20-s single-limb stance trials in conditions 1 and 2. An adjusted coefficient of multiple determination statistic was used to compare stance limb three-dimensional kinematic data for similarity to establish patterns of interjoint coordination. The fractal dimension of the stance limb center of pressure path was also calculated. Between-group analyses revealed that participants with CAI displayed notable increases in ankle-hip linked coordination compared with both lateral ankle sprain "copers" (-0.52 (1.05) vs 0.28 (0.9), P = 0.007) and controls (-0.52 (1.05) vs 0.63 (0.64), P = 0.006) in condition 1 and compared with controls only (0.62 (1.92) vs 0.1 (1.0) P = 0.002) in condition 2. Participants with CAI also exhibited a decrease in the fractal dimension of the center-of-pressure path during condition 2 compared with both controls and lateral ankle sprain "copers." Participants with CAI present with a hip-dominant strategy of eyes-open and eyes-closed static unipedal stance. This coincided with reduced complexity of the stance limb center of pressure path in the eyes-closed condition.

HELIO: The Heliophysics Integrated Observatory

NASA Technical Reports Server (NTRS)

Bentley, R. D.; Csillaghy, A.; Aboudarham, J.; Jacquey, C.; Hapgood, M. A.; Bocchialini, K.; Messerotti, M.; Brooke, J.; Gallagher, P.; Fox, P.;

Managing coherence via put/get windows

DOEpatents

Blumrich, Matthias A [Ridgefield, CT; Chen, Dong [Croton on Hudson, NY; Coteus, Paul W [Yorktown Heights, NY; Gara, Alan G [Mount Kisco, NY; Giampapa, Mark E [Irvington, NY; Heidelberger, Philip [Cortlandt Manor, NY; Hoenicke, Dirk [Ossining, NY; Ohmacht, Martin [Yorktown Heights, NY

2011-01-11

A method and apparatus for managing coherence between two processors of a two processor node of a multi-processor computer system. Generally the present invention relates to a software algorithm that simplifies and significantly speeds the management of cache coherence in a message passing parallel computer, and to hardware apparatus that assists this cache coherence algorithm. The software algorithm uses the opening and closing of put/get windows to coordinate the activated required to achieve cache coherence. The hardware apparatus may be an extension to the hardware address decode, that creates, in the physical memory address space of the node, an area of virtual memory that (a) does not actually exist, and (b) is therefore able to respond instantly to read and write requests from the processing elements.

Managing coherence via put/get windows

DOEpatents

Blumrich, Matthias A [Ridgefield, CT; Chen, Dong [Croton on Hudson, NY; Coteus, Paul W [Yorktown Heights, NY; Gara, Alan G [Mount Kisco, NY; Giampapa, Mark E [Irvington, NY; Heidelberger, Philip [Cortlandt Manor, NY; Hoenicke, Dirk [Ossining, NY; Ohmacht, Martin [Yorktown Heights, NY

2012-02-21

A method and apparatus for managing coherence between two processors of a two processor node of a multi-processor computer system. Generally the present invention relates to a software algorithm that simplifies and significantly speeds the management of cache coherence in a message passing parallel computer, and to hardware apparatus that assists this cache coherence algorithm. The software algorithm uses the opening and closing of put/get windows to coordinate the activated required to achieve cache coherence. The hardware apparatus may be an extension to the hardware address decode, that creates, in the physical memory address space of the node, an area of virtual memory that (a) does not actually exist, and (b) is therefore able to respond instantly to read and write requests from the processing elements.

Academia's role in Test Ban Treaty monitoring remains unresolved

NASA Astrophysics Data System (ADS)

Wakefield, J.

However, some progress has been made in negotiating how this university consortium will be coordinated with the federal government's efforts to develop comprehensive nuclear test ban monitoring systems. Before Congress closed shop, changes were made in the conference wording of a Defense authorization bill for fiscal year 1995 that covers seismic research. Instead of requiring the secretaries of Defense and State to sign off on all seismic projects for monitoring nuclear explosions before the funds may be obligated, as the Senate version of the bill originally proposed, the seismic projects must now be approved by an existing annual review group, which was established by a classified presidential directive. In addition, some of the controversial language in a complementing Senate report will be changed.

Close Range Calibration of Long Focal Length Lenses in a Changing Environment

NASA Astrophysics Data System (ADS)

Robson, Stuart; MacDonald, Lindsay; Kyle, Stephen; Shortis, Mark R.

2016-06-01

University College London is currently developing a large-scale multi-camera system for dimensional control tasks in manufacturing, including part machining, assembly and tracking, as part of the Light Controlled Factory project funded by the UK Engineering and Physical Science Research Council. In parallel, as part of the EU LUMINAR project funded by the European Association of National Metrology Institutes, refraction models of the atmosphere in factory environments are being developed with the intent of modelling and eliminating the effects of temperature and other variations. The accuracy requirements for both projects are extremely demanding, so accordingly improvements in the modelling of both camera imaging and the measurement environment are essential. At the junction of these two projects lies close range camera calibration. The accurate and reliable calibration of cameras across a realistic range of atmospheric conditions in the factory environment is vital in order to eliminate systematic errors. This paper demonstrates the challenge of experimentally isolating environmental effects at the level of a few tens of microns. Longer lines of sight promote the use and calibration of a near perfect perspective projection from a Kern 75mm lens with maximum radial distortion of the order of 0.5m. Coordination of a reference target array, representing a manufactured part, is achieved to better than 0.1mm at a standoff of 8m. More widely, results contribute to better sensor understanding, improved mathematical modelling of factory environments and more reliable coordination of targets to 0.1mm and better over large volumes.

Interpersonal Coordination: Methods, Achievements, and Challenges

PubMed Central

Cornejo, Carlos; Cuadros, Zamara; Morales, Ricardo; Paredes, Javiera

2017-01-01

Research regarding interpersonal coordination can be traced back to the early 1960s when video recording began to be utilized in communication studies. Since then, technological advances have extended the range of techniques that can be used to accurately study interactional phenomena. Although such a diversity of methods contributes to the improvement of knowledge concerning interpersonal coordination, it has become increasingly difficult to maintain a comprehensive view of the field. In the present article, we review the main capture methods by describing their major findings, levels of description and limitations. We group them into three categories: video analysis, motion tracking, and psychophysiological and neurophysiological techniques. Revised evidence suggests that interpersonal coordination encompasses a family of morphological and temporal synchronies at different levels and that it is closely related to the construction and maintenance of a common social and affective space. We conclude by arguing that future research should address methodological challenges to advance the understanding of coordination phenomena. PMID:29021769

75 FR 74648 - Fisheries of the Caribbean, Gulf of Mexico, and South Atlantic; Emergency Fisheries Closure in...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-01

... will be updated on a regular basis and announced to the public via NOAA Weather Radio, Fishery Bulletin... area as needed (on a daily or weekly basis) and announce the revised closed area via NOAA Weather Radio... obtain the updated boundary coordinates for the fishery closed area by listening to NOAA Weather Radio...

One-dimensional cuts through multidimensional potential-energy surfaces by tunable x rays

NASA Astrophysics Data System (ADS)

Eckert, Sebastian; da Cruz, Vinícius Vaz; Gel'mukhanov, Faris; Ertan, Emelie; Ignatova, Nina; Polyutov, Sergey; Couto, Rafael C.; Fondell, Mattis; Dantz, Marcus; Kennedy, Brian; Schmitt, Thorsten; Pietzsch, Annette; Odelius, Michael; Föhlisch, Alexander

2018-05-01

The concept of the potential-energy surface (PES) and directional reaction coordinates is the backbone of our description of chemical reaction mechanisms. Although the eigenenergies of the nuclear Hamiltonian uniquely link a PES to its spectrum, this information is in general experimentally inaccessible in large polyatomic systems. This is due to (near) degenerate rovibrational levels across the parameter space of all degrees of freedom, which effectively forms a pseudospectrum given by the centers of gravity of groups of close-lying vibrational levels. We show here that resonant inelastic x-ray scattering (RIXS) constitutes an ideal probe for revealing one-dimensional cuts through the ground-state PES of molecular systems, even far away from the equilibrium geometry, where the independent-mode picture is broken. We strictly link the center of gravity of close-lying vibrational peaks in RIXS to a pseudospectrum which is shown to coincide with the eigenvalues of an effective one-dimensional Hamiltonian along the propagation coordinate of the core-excited wave packet. This concept, combined with directional and site selectivity of the core-excited states, allows us to experimentally extract cuts through the ground-state PES along three complementary directions for the showcase H2O molecule.

National Coordinating Committee for Technology in Education and Training (NCC-TET) Requirements for the National Information Infrastructure (NII).

ERIC Educational Resources Information Center

Yrchik, John; Cradler, John

1994-01-01

Discusses guidelines that were developed to ensure that the National Information Infrastructure provides expanded opportunities for education and training. Topics include access requirements for homes and work places as well as schools; education and training application requirements, including coordination by federal departments and agencies; and…

Toda Systems, Cluster Characters, and Spectral Networks

NASA Astrophysics Data System (ADS)

Williams, Harold

2016-11-01

We show that the Hamiltonians of the open relativistic Toda system are elements of the generic basis of a cluster algebra, and in particular are cluster characters of nonrigid representations of a quiver with potential. Using cluster coordinates defined via spectral networks, we identify the phase space of this system with the wild character variety related to the periodic nonrelativistic Toda system by the wild nonabelian Hodge correspondence. We show that this identification takes the relativistic Toda Hamiltonians to traces of holonomies around a simple closed curve. In particular, this provides nontrivial examples of cluster coordinates on SL n -character varieties for n > 2 where canonical functions associated to simple closed curves can be computed in terms of quivers with potential, extending known results in the SL 2 case.

Marine Corps Close Air Support Development from Guadalcanal to Okinawa

DTIC Science & Technology

2011-03-05

air support (CAS) of troops in contact with the enemy came of age . While the capability clearly had potential, issues of coordination, accurate...including the first use of an Air Support Control Unit ( ASCU ), predecessor of the Fire S.upport Coordination Center.71 The Command Ship initially...which artillery had to cease fire for low- level napalm air strikes. When two or more battalions fired on the same location, the ASCU used maximum

Kinematic performance of fine motor control in attention-deficit/hyperactivity disorder: the effects of comorbid developmental coordination disorder and core symptoms.

PubMed

Lee, I-Ching; Chen, Yung-Jung; Tsai, Chin-Liang

2013-02-01

The aims of this study were: (i) to determine whether differences exist in the fine motor fluency and flexibility of three groups (children with attention-deficit/hyperactivity disorder [ADHD], children in whom ADHD is comorbid with developmental coordination disorder [DCD] [denoted as ADHD+DCD], and a typically developing control group); and (ii) to clarify whether the degree of severity of core symptoms affects performance. The Peabody Picture Vocabulary Test-Revised, the Beery-Buktenica Development Test of Visual-Motor Integration and the Movement Assessment Battery for Children were used as prescreening tests. The Integrated Visual and Auditory+Plus test was utilized to assess subjects' attention. The redesigned fine motor tracking and pursuit tasks were administered to evaluate subjects' fine motor performance. No significant difference was found when comparing the performance of the Children with ADHD and the typically developing group. Significant differences existed between children in whom ADHD is comorbid with DCD and typically developing children. Children with ADHD demonstrated proper fine motor fluency and flexibility, and deficient performance occurred when ADHD was comorbid with developmental coordination disorder. Children with ADHD had more difficulty implementing closed-loop movements that required higher levels of cognitive processing than those of their typically developing peers. Also, deficits in fine motor control were more pronounced when ADHD was combined with movement coordination problems. The severity of core symptoms had a greater effect on children with ADHD's fine motor flexibility than did fluency performance. In children with pure ADHD, unsmooth movement performance was highly related to the severity of core symptoms. © 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society.

Adaptation of multijoint coordination during standing balance in healthy young and healthy old individuals

PubMed Central

Pasma, J. H.; Schouten, A. C.; Aarts, R. G. K. M.; Meskers, C. G. M.; Maier, A. B.; van der Kooij, H.

2015-01-01

Standing balance requires multijoint coordination between the ankles and hips. We investigated how humans adapt their multijoint coordination to adjust to various conditions and whether the adaptation differed between healthy young participants and healthy elderly. Balance was disturbed by push/pull rods, applying two continuous and independent force disturbances at the level of the hip and between the shoulder blades. In addition, external force fields were applied, represented by an external stiffness at the hip, either stabilizing or destabilizing the participants' balance. Multivariate closed-loop system-identification techniques were used to describe the neuromuscular control mechanisms by quantifying the corrective joint torques as a response to body sway, represented by frequency response functions (FRFs). Model fits on the FRFs resulted in an estimation of time delays, intrinsic stiffness, reflexive stiffness, and reflexive damping of both the ankle and hip joint. The elderly generated similar corrective joint torques but had reduced body sway compared with the young participants, corresponding to the increased FRF magnitude with age. When a stabilizing or destabilizing external force field was applied at the hip, both young and elderly participants adapted their multijoint coordination by lowering or respectively increasing their neuromuscular control actions around the ankles, expressed in a change of FRF magnitude. However, the elderly adapted less compared with the young participants. Model fits on the FRFs showed that elderly had higher intrinsic and reflexive stiffness of the ankle, together with higher time delays of the hip. Furthermore, the elderly adapted their reflexive stiffness around the ankle joint less compared with young participants. These results imply that elderly were stiffer and were less able to adapt to external force fields. PMID:26719084

Exploitation of knowledge databases in the synthesis of zinc(II) malonates with photo-sensitive and photo-insensitive N,N'-containing linkers.

PubMed

Zorina-Tikhonova, Ekaterina N; Chistyakov, Aleksandr S; Kiskin, Mikhail A; Sidorov, Aleksei A; Dorovatovskii, Pavel V; Zubavichus, Yan V; Voronova, Eugenia D; Godovikov, Ivan A; Korlyukov, Alexander A; Eremenko, Igor L; Vologzhanina, Anna V

2018-05-01

Photoinitiated solid-state reactions are known to affect the physical properties of coordination polymers, such as fluorescence and sorption behaviour, and also afford extraordinary architectures ( e.g. three-periodic structures with polyorganic ligands). However, the construction of novel photo-sensitive coordination polymers requires an understanding of the factors which govern the mutual disposition of reactive fragments. A series of zinc(II) malonate complexes with 1,2-bis(pyridin-4-yl)ethylene and its photo-insensitive analogues has been synthesized for the purpose of systematic analysis of their underlying nets and mutual disposition of N -donor ligands. The application of a big data-set analysis for the prediction of a variety of possible complex compositions, coordination environments and networks for a four-component system has been demonstrated for the first time. Seven of the nine compounds possess one of the highly probable topologies for their underlying nets; in addition, two novel closely related four-coordinated networks were obtained. Complexes containing 1,2-bis(pyridin-4-yl)ethylene and 1,2-bis(pyridin-4-yl)ethane form isoreticular compounds more readily than those with 4,4'-bipyridine and 1,2-bis(pyridin-4-yl)ethylene. The effects of the precursor, either zinc(II) nitrate or zinc(II) acetate, on the composition and dimensionality of the resulting architecture are discussed. For three of the four novel complexes containing 1,2-bis(pyridin-4-yl)ethylene, the single-crystal-to-single-crystal [2 + 2] cycloaddition reactions were carried out. UV irradiation of these crystals afforded either the 0D→1D or the 3D→3D transformations, with and without network changes. One of the two 3D→3D transformations was accompanied by solvent (H 2 O) cleavage.

Community Currency Trading Method through Partial Transaction Intermediary Process

NASA Astrophysics Data System (ADS)

Kido, Kunihiko; Hasegawa, Seiichi; Komoda, Norihisa

A community currency is local money that is issued by local governments or Non-Profit Organization (NPO) to support social services. The purpose of introducing community currencies is to regenerate communities by fostering mutual aids among community members. In this paper, we propose a community currency trading method through partial intermediary process, under operational environments without introducing coordinators all the time. In this method, coordinators perform coordination between service users and service providers during several months from the start point of transactions. After the period of coordination, participants spontaneously make transactions based on their trust area and a trust evaluation method based on the number of provided services and complaint information. This method is especially effective to communities with close social networks and low trustworthiness. The proposed method is evaluated through multi-agent simulation.

Receptive fields for smooth pursuit eye movements and motion perception.

PubMed

Debono, Kurt; Schütz, Alexander C; Spering, Miriam; Gegenfurtner, Karl R

2010-12-01

Humans use smooth pursuit eye movements to track moving objects of interest. In order to track an object accurately, motion signals from the target have to be integrated and segmented from motion signals in the visual context. Most studies on pursuit eye movements used small visual targets against a featureless background, disregarding the requirements of our natural visual environment. Here, we tested the ability of the pursuit and the perceptual system to integrate motion signals across larger areas of the visual field. Stimuli were random-dot kinematograms containing a horizontal motion signal, which was perturbed by a spatially localized, peripheral motion signal. Perturbations appeared in a gaze-contingent coordinate system and had a different direction than the main motion including a vertical component. We measured pursuit and perceptual direction discrimination decisions and found that both steady-state pursuit and perception were influenced most by perturbation angles close to that of the main motion signal and only in regions close to the center of gaze. The narrow direction bandwidth (26 angular degrees full width at half height) and small spatial extent (8 degrees of visual angle standard deviation) correspond closely to tuning parameters of neurons in the middle temporal area (MT). Copyright © 2010 Elsevier Ltd. All rights reserved.

Researcher perspectives on competencies of return-to-work coordinators.

PubMed

Gardner, Bethany T; Pransky, Glenn; Shaw, William S; Hong, Qua Nha; Loisel, Patrick

2010-01-01

Return-to-work (RTW) coordination programs are successful in reducing long-term work disability, but research reports have not adequately described the role and competencies of the RTW coordinator. This study was conducted to clarify the impact of RTW coordinators, and competencies (knowledge, skills, and attitudes) required to achieve optimal RTW outcomes in injured workers. Studies involving RTW coordination for injured workers were identified through literature review. Semi-structured interviews were conducted with 12 principal investigators to obtain detailed information about the RTW coordinator role and competencies not included in published articles. Interview results were synthesized into principal conceptual groups by affinity mapping. All investigators strongly endorsed the role of RTW coordinator as key to the program's success. Affinity mapping identified 10 groups of essential competencies: (1) individual traits/qualities, (2) relevant knowledge base, (3) RTW focus and attitude, (4) organizational/administrative skills, (5) assessment skills, (6) communication skills, (7) interpersonal relationship skills, (8) conflict resolution skills, (9) problem-solving skills, and (10) RTW facilitation skills. Specific consensus competencies were identified within each affinity group. Most investigators endorsed similar competencies, although there was some variation by setting or scope of RTW intervention. RTW coordinators are essential contributors in RTW facilitation programs. This study identified specific competencies required to achieve success. More emphasis on mentorship and observation will be required to develop and evaluate necessary skills in this area.

Effects of microscale inertia on heat or mass transfer from a drop

NASA Astrophysics Data System (ADS)

Krishnamurthy, Deepak; Subramanian, Ganesh

2012-11-01

Heat or mass transport from suspensions of solid particles or drops is ubiquitous in many industrial processes. In the zero inertia limit the transport is diffusion limited owing to the presence of closed streamlines around each particle. A small but finite amount of inertia though, results in a vastly different picture, greatly enhancing transport by destroying the closed streamline configuration. We develop a theoretical formulation to study the effects of weak inertia on transport from a density-matched drop in a 2D linear flow. It is shown that, unlike a solid particle, the near-surface streamlines are closed only when the viscosity ratio (λ) exceeds a critical value λc = 2 α / (1- α) , where α is the linear flow parameter measuring relative magnitudes of extension and vorticity. The velocity field on the drop surface can be characterized using a complex-valued analogue of the (C, τ) coordinate system used to describe Jeffrey orbits of an axisymmetric particle. In the open-streamline case (λ < λ c) , convective transport occurs even with zero inertia, and for large Peclet number (Pe) (the relative magnitude of convective to diffusive transport), the Nusselt number (dimensionless rate of heat transfer) is expected to scale as F(α, λ) Pe1/2 and is determined via a boundary layer analysis in the (C, τ) coordinate system. In the closed streamline case (λ > λ c) , similar to the solid particle, inertia plays a crucial role, and the Nusselt number must scale as G(α, λ)Re1/2Pe1/2. A methodology is developed to analyze the convection along spiraling streamlines using a physically motivated choice of coordinate system on the drop surface.

Collision Avoidance: Coordination of Predicted Conjunctions between NASA Satellites and Satellites of other Countries

NASA Astrophysics Data System (ADS)

Kelly, A.; Watson, W.

2014-09-01

This paper describes one of the challenges facing the flight operations teams of the International Earth Observing constellation satellites at the 705 km orbit, including NASAs satellites. The NASA Earth Science Mission Operations (ESMO) Project has been dealing with predicted conjunctions (close approach) between operational/non-operational space objects and the satellites in the International Earth observing constellations for several years. Constellation satellites include: NASAs Earth Observing System (EOS) Terra, Aqua, and Aura, CloudSat, the joint NASA/CNES CALIPSO mission, Earth Observing 1 (EO-1), the Japan Aerospace and Exploration Agency (JAXA) Global Change Observation Mission-Water 1 (GCOM-W1) mission, the United States Geological Survey (USGS) Landsat 7 and Landsat 8, and until 2013, Argentinas SAC-C mission and the CNES PARASOL mission. The NASA Conjunction Analysis and Risk Assessment (CARA) team provides daily reports to the ESMO Project regarding any high interest close approach events (HIEs) involving the constellation satellites. The daily CARA reports provide risk assessment results that help the operations teams to determine if there is a need to perform a risk mitigation action. If the conjuncting space object is an operational satellite that is capable of maneuvering, the affected satellite team needs to coordinate their action plan with the owner operator of the conjuncting satellite. It is absolutely critical for the two teams to communicate as soon as possible. The goal is to minimize the collision risk; this can happen if both satellite operators do not coordinate their maneuver plans. The constellation teams have established guidelines for coordinating HIEs. This coordination process has worked successfully for several years for satellites that are operated by other organizations in the United States and by NASAs international partners, all with whom NASA has a cooperative agreement. However, the situation is different for HIEs with satellites of foreign operators that do not have an agreement with NASA and the constellation organizations. The current process for coordinating close approach events is neither timely nor satisfactory. Due to the concern that NASAs multi-billion dollar assets at the 705 km orbit can be wiped out by a collision with satellites of foreign operators, the NASA ESMO Project and the CARA team are proposing a more timely coordination and communication process to resolve and safely mitigate these HIEs. This proposed process does not violate any existing communication constraints between the United States and certain foreign operators. This proposal, as described in this paper, will be presented at the conference and comments from other satellite operators will be welcomed and greatly appreciated.

48 CFR 952.223-78 - Sustainable acquisition program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... activities with and submit required reports through the Environmental Sustainability Coordinator or... reports through the Environmental Sustainability Coordinator or equivalent position. Reporting under this... prepare and submit performance reports, if required, using prescribed DOE formats, at the end of the...

47 CFR 25.262 - Licensing and domestic coordination requirements for 17/24 GHz BSS space stations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... requirements for 17/24 GHz BSS space stations. 25.262 Section 25.262 Telecommunication FEDERAL COMMUNICATIONS... Licensing and domestic coordination requirements for 17/24 GHz BSS space stations. (a) Except as described in paragraphs (b), (c) or (e) of this section, applicants seeking to operate a space station in the...

47 CFR 25.262 - Licensing and domestic coordination requirements for 17/24 GHz BSS space stations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... requirements for 17/24 GHz BSS space stations. 25.262 Section 25.262 Telecommunication FEDERAL COMMUNICATIONS... Licensing and domestic coordination requirements for 17/24 GHz BSS space stations. (a) Except as described in paragraphs (b), (c) or (e) of this section, applicants seeking to operate a space station in the...

47 CFR 25.262 - Licensing and domestic coordination requirements for 17/24 GHz BSS space stations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... requirements for 17/24 GHz BSS space stations. 25.262 Section 25.262 Telecommunication FEDERAL COMMUNICATIONS... Licensing and domestic coordination requirements for 17/24 GHz BSS space stations. (a) Except as described in paragraphs (b), (c) or (e) of this section, applicants seeking to operate a space station in the...

47 CFR 25.262 - Licensing and domestic coordination requirements for 17/24 GHz BSS space stations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... requirements for 17/24 GHz BSS space stations. 25.262 Section 25.262 Telecommunication FEDERAL COMMUNICATIONS... Licensing and domestic coordination requirements for 17/24 GHz BSS space stations. (a) Except as described in paragraphs (b), (c) or (e) of this section, applicants seeking to operate a space station in the...

Structural Characterization of Poorly-Crystalline Scorodite, Iron (III)-arsenate Co-precipitates and Uranium Millneutralized Raffinate Solids using X-ray Absorption Fine Structure Spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, N.; Jiang, D; Cutler, J

X-ray absorption fine structure (XAFS) is used to characterize the mineralogy of the iron(III)-arsenate(V) precipitates produced during the raffinate (aqueous effluent) neutralization process at the McClean Lake uranium mill in northern Saskatchewan, Canada. To facilitate the structural characterization of the precipitated solids derived from the neutralized raffinate, a set of reference compounds were synthesized and analyzed. The reference compounds include crystalline scorodite, poorly-crystalline scorodite, iron(III)-arsenate co-precipitates obtained under different pH conditions, and arsenate-adsorbed on goethite. The poorly-crystalline scorodite (prepared at pH 4 with Fe/As = 1) has similar As local structure as that of crystalline scorodite. Both As and Femore » K-edge XAFS of poorly-crystalline scorodite yield consistent results on As-Fe (or Fe-As) shell. From As K-edge analysis the As-Fe shell has an inter-atomic distance of 3.33 {+-} 0.02 A and coordination number of 3.2; while from Fe K-edge analysis the Fe-As distance and coordination number are 3.31 {+-} 0.02 A and 3.8, respectively. These are in contrast with the typical arsenate adsorption on bidentate binuclear sites on goethite surfaces, where the As-Fe distance is 3.26 {+-} 0.03 A and coordination number is close to 2. A similar local structure identified in the poorly-crystalline scorodite is also found in co-precipitation solids (Fe(III)/As(V) = 3) when precipitated at the same pH (pH = 4): As-Fe distance 3.30 {+-} 0.03 A and coordination number 3.9; while at pH = 8 the co-precipitate has As-Fe distance of 3.27 {+-} 0.03 A and coordination number about 2, resembling more closely the adsorption case. The As local structure in the two neutralized raffinate solid series (precipitated at pH values up to 7) closely resembles that in the poorly-crystalline scorodite. All of the raffinate solids have the same As-Fe inter-atomic distance as that in the poorly-crystalline scorodite, and a systematic decrease in the As-Fe coordination is observed when pH is progressively increased; the basic poorly-crystalline scorodite structural feature remains in the raffinate solid up to pH 7.« less

Structural characterization of poorly-crystalline scorodite, iron(III)-arsenate co-precipitates and uranium mill neutralized raffinate solids using X-ray absorption fine structure spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, N; Jiang, D T; Cutler, J

X-ray absorption fine structure (XAFS) is used to characterize the mineralogy of the iron(III)-arsenate(V) precipitates produced during the raffinate (aqueous effluent) neutralization process at the McClean Lake uranium mill in northern Saskatchewan, Canada. To facilitate the structural characterization of the precipitated solids derived from the neutralized raffinate, a set of reference compounds were synthesized and analyzed. The reference compounds include crystalline scorodite, poorly-crystalline scorodite, iron(III)-arsenate co-precipitates obtained under different pH conditions, and arsenate-adsorbed on goethite. The poorly-crystalline scorodite (prepared at pH 4 with Fe/As = 1) has similar As local structure as that of crystalline scorodite. Both As and Femore » K-edge XAFS of poorly-crystalline scorodite yield consistent results on As-Fe (or Fe-As) shell. From As K-edge analysis the As-Fe shell has an inter-atomic distance of 3.33 ± 0.02 Å and coordination number of 3.2; while from Fe K-edge analysis the Fe-As distance and coordination number are 3.31 ± 0.02 Å and 3.8, respectively. These are in contrast with the typical arsenate adsorption on bidentate binuclear sites on goethite surfaces, where the As-Fe distance is 3.26 ± 0.03 Å and coordination number is close to 2. A similar local structure identified in the poorly-crystalline scorodite is also found in co-precipitation solids (Fe(III)/As(V) = 3) when precipitated at the same pH (pH = 4): As-Fe distance 3.30 ± 0.03 Å and coordination number 3.9; while at pH = 8 the co-precipitate has As-Fe distance of 3.27 ± 0.03 Å and coordination number about 2, resembling more closely the adsorption case. The As local structure in the two neutralized raffinate solid series (precipitated at pH values up to 7) closely resembles that in the poorly-crystalline scorodite. All of the raffinate solids have the same As-Fe inter-atomic distance as that in the poorly-crystalline scorodite, and a systematic decrease in the As-Fe coordination is observed when pH is progressively increased; the basic poorly-crystalline scorodite structural feature remains in the raffinate solid up to pH 7.« less

75 FR 57690 - Acquisition Regulation: Sustainable Acquisition

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-22

... coordinate its activities with and submit required reports through the Environmental Sustainability... reports directly to the Prime Contractor's Environmental Sustainability Coordinator at the supported... reports through the Environmental Sustainability Coordinator or equivalent position. Reporting under this...

48 CFR 952.223-78 - Sustainable acquisition program.

Code of Federal Regulations, 2014 CFR

2014-10-01

... activities with and submit required reports through the Environmental Sustainability Coordinator or... Prime Contractor's Environmental Sustainability Coordinator at the supported facility. The Subcontractor... reports through the Environmental Sustainability Coordinator or equivalent position. Reporting under this...

48 CFR 952.223-78 - Sustainable acquisition program.

Code of Federal Regulations, 2012 CFR

2012-10-01

... activities with and submit required reports through the Environmental Sustainability Coordinator or... Prime Contractor's Environmental Sustainability Coordinator at the supported facility. The Subcontractor... reports through the Environmental Sustainability Coordinator or equivalent position. Reporting under this...

48 CFR 952.223-78 - Sustainable acquisition program.

Code of Federal Regulations, 2011 CFR

2011-10-01

... activities with and submit required reports through the Environmental Sustainability Coordinator or... Prime Contractor's Environmental Sustainability Coordinator at the supported facility. The Subcontractor... reports through the Environmental Sustainability Coordinator or equivalent position. Reporting under this...

48 CFR 952.223-78 - Sustainable acquisition program.

Code of Federal Regulations, 2013 CFR

2013-10-01

... activities with and submit required reports through the Environmental Sustainability Coordinator or... Prime Contractor's Environmental Sustainability Coordinator at the supported facility. The Subcontractor... reports through the Environmental Sustainability Coordinator or equivalent position. Reporting under this...

Curvature estimation for multilayer hinged structures with initial strains

NASA Astrophysics Data System (ADS)

Nikishkov, G. P.

2003-10-01

Closed-form estimate of curvature for hinged multilayer structures with initial strains is developed. The finite element method is used for modeling of self-positioning microstructures. The geometrically nonlinear problem with large rotations and large displacements is solved using step procedure with node coordinate update. Finite element results for curvature of the hinged micromirror with variable width is compared to closed-form estimates.

A Closed-Form Error Model of Straight Lines for Improved Data Association and Sensor Fusing

PubMed Central

2018-01-01

Linear regression is a basic tool in mobile robotics, since it enables accurate estimation of straight lines from range-bearing scans or in digital images, which is a prerequisite for reliable data association and sensor fusing in the context of feature-based SLAM. This paper discusses, extends and compares existing algorithms for line fitting applicable also in the case of strong covariances between the coordinates at each single data point, which must not be neglected if range-bearing sensors are used. Besides, in particular, the determination of the covariance matrix is considered, which is required for stochastic modeling. The main contribution is a new error model of straight lines in closed form for calculating quickly and reliably the covariance matrix dependent on just a few comprehensible and easily-obtainable parameters. The model can be applied widely in any case when a line is fitted from a number of distinct points also without a priori knowledge of the specific measurement noise. By means of extensive simulations, the performance and robustness of the new model in comparison to existing approaches is shown. PMID:29673205

CHD1 regulates cell fate determination by activation of differentiation-induced genes

PubMed Central

Baumgart, Simon J.; Najafova, Zeynab; Hossan, Tareq; Xie, Wanhua; Nagarajan, Sankari; Kari, Vijayalakshmi; Ditzel, Nicholas; Kassem, Moustapha

2017-01-01

Abstract The coordinated temporal and spatial activation of gene expression is essential for proper stem cell differentiation. The Chromodomain Helicase DNA-binding protein 1 (CHD1) is a chromatin remodeler closely associated with transcription and nucleosome turnover downstream of the transcriptional start site (TSS). In this study, we show that CHD1 is required for the induction of osteoblast-specific gene expression, extracellular-matrix mineralization and ectopic bone formation in vivo. Genome-wide occupancy analyses revealed increased CHD1 occupancy around the TSS of differentiation-activated genes. Furthermore, we observed that CHD1-dependent genes are mainly induced during osteoblast differentiation and are characterized by higher levels of CHD1 occupancy around the TSS. Interestingly, CHD1 depletion resulted in increased pausing of RNA Polymerase II (RNAPII) and decreased H2A.Z occupancy close to the TSS, but not at enhancer regions. These findings reveal a novel role for CHD1 during osteoblast differentiation and provide further insights into the intricacies of epigenetic regulatory mechanisms controlling cell fate determination. PMID:28475736

CHD1 regulates cell fate determination by activation of differentiation-induced genes.

PubMed

Baumgart, Simon J; Najafova, Zeynab; Hossan, Tareq; Xie, Wanhua; Nagarajan, Sankari; Kari, Vijayalakshmi; Ditzel, Nicholas; Kassem, Moustapha; Johnsen, Steven A

2017-07-27

The coordinated temporal and spatial activation of gene expression is essential for proper stem cell differentiation. The Chromodomain Helicase DNA-binding protein 1 (CHD1) is a chromatin remodeler closely associated with transcription and nucleosome turnover downstream of the transcriptional start site (TSS). In this study, we show that CHD1 is required for the induction of osteoblast-specific gene expression, extracellular-matrix mineralization and ectopic bone formation in vivo. Genome-wide occupancy analyses revealed increased CHD1 occupancy around the TSS of differentiation-activated genes. Furthermore, we observed that CHD1-dependent genes are mainly induced during osteoblast differentiation and are characterized by higher levels of CHD1 occupancy around the TSS. Interestingly, CHD1 depletion resulted in increased pausing of RNA Polymerase II (RNAPII) and decreased H2A.Z occupancy close to the TSS, but not at enhancer regions. These findings reveal a novel role for CHD1 during osteoblast differentiation and provide further insights into the intricacies of epigenetic regulatory mechanisms controlling cell fate determination. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

Redox-active porous coordination polymer based on trinuclear pivalate: Temperature-dependent crystal rearrangement and redox-behavior

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lytvynenko, Anton S.; Kiskin, Mikhail A., E-mail: mkiskin@igic.ras.ru; Dorofeeva, Victoria N.

2015-03-15

Linking of trinuclear pivalate Fe{sub 2}NiO(Piv){sub 6} (Piv=O{sub 2}CC(CH{sub 3}){sub 3}) by 2,6-bis(4-pyridyl)-4-(1-naphthyl)pyridine (L) resulted in formation of 1D-porous coordination polymer Fe{sub 2}NiO(Piv){sub 6}(L)·Solv, which was characterized in two forms: DMSO solvate Fe{sub 2}NiO(Piv){sub 6}(L)(DMSO)·2.5DMSO (1) or water solvate Fe{sub 2}NiO(Piv){sub 6}(L)(H{sub 2}O) (2). X-ray structure of 1 was determined. Crystal lattice of 1 at 160 K contained open channels, filled by captured solvent, while temperature growth to 296 K led to the crystal lattice rearrangement and formation of closed voids. Redox-behavior of 2 was studied by cyclic voltammetry for a solid compound, deposited on glassy-carbon electrode. Redox-activity of Lmore » preserved upon incorporation in the coordination polymer. The presence of pores in desolvated sample Fe{sub 2}NiO(Piv){sub 6}(L) was confirmed by the measurements of N{sub 2} and H{sub 2} adsorption at 77 K. Potential barriers of the different molecules diffusion through pores were estimated by the means of molecular mechanics. - Graphical abstract: Redox-behavior of 1D-porous coordination polymer Fe{sub 2}NiO(Piv){sub 6}(L)(H{sub 2}O) was studied by cyclic voltammetry in thin film, deposited on glassy-carbon electrode. Redox-activity of L preserved upon incorporation in the coordination polymer. Potential barriers of different molecules diffusion through pores were estimated by the means of molecular mechanics. - Highlights: • Porous 1D coordination polymer was synthesized. • Temperature growth led to pores closing due to crystal lattice rearrangement. • Redox-activity of ligand preserved upon incorporation into coordination polymer. • Redox-properties of solid coordination polymer were studied in thin film. • Diffusion barriers were evaluated by molecular mechanics.« less

Development of Extended Ray-tracing method including diffraction, polarization and wave decay effects

NASA Astrophysics Data System (ADS)

Yanagihara, Kota; Kubo, Shin; Dodin, Ilya; Nakamura, Hiroaki; Tsujimura, Toru

2017-10-01

Geometrical Optics Ray-tracing is a reasonable numerical analytic approach for describing the Electron Cyclotron resonance Wave (ECW) in slowly varying spatially inhomogeneous plasma. It is well known that the result with this conventional method is adequate in most cases. However, in the case of Helical fusion plasma which has complicated magnetic structure, strong magnetic shear with a large scale length of density can cause a mode coupling of waves outside the last closed flux surface, and complicated absorption structure requires a strong focused wave for ECH. Since conventional Ray Equations to describe ECW do not have any terms to describe the diffraction, polarization and wave decay effects, we can not describe accurately a mode coupling of waves, strong focus waves, behavior of waves in inhomogeneous absorption region and so on. For fundamental solution of these problems, we consider the extension of the Ray-tracing method. Specific process is planned as follows. First, calculate the reference ray by conventional method, and define the local ray-base coordinate system along the reference ray. Then, calculate the evolution of the distributions of amplitude and phase on ray-base coordinate step by step. The progress of our extended method will be presented.

Decentralized Adaptive Neural Output-Feedback DSC for Switched Large-Scale Nonlinear Systems.

PubMed

Lijun Long; Jun Zhao

2017-04-01

In this paper, for a class of switched large-scale uncertain nonlinear systems with unknown control coefficients and unmeasurable states, a switched-dynamic-surface-based decentralized adaptive neural output-feedback control approach is developed. The approach proposed extends the classical dynamic surface control (DSC) technique for nonswitched version to switched version by designing switched first-order filters, which overcomes the problem of multiple "explosion of complexity." Also, a dual common coordinates transformation of all subsystems is exploited to avoid individual coordinate transformations for subsystems that are required when applying the backstepping recursive design scheme. Nussbaum-type functions are utilized to handle the unknown control coefficients, and a switched neural network observer is constructed to estimate the unmeasurable states. Combining with the average dwell time method and backstepping and the DSC technique, decentralized adaptive neural controllers of subsystems are explicitly designed. It is proved that the approach provided can guarantee the semiglobal uniformly ultimately boundedness for all the signals in the closed-loop system under a class of switching signals with average dwell time, and the tracking errors to a small neighborhood of the origin. A two inverted pendulums system is provided to demonstrate the effectiveness of the method proposed.

Automatic extraction of the mid-sagittal plane using an ICP variant

NASA Astrophysics Data System (ADS)

Fieten, Lorenz; Eschweiler, Jörg; de la Fuente, Matías; Gravius, Sascha; Radermacher, Klaus

2008-03-01

Precise knowledge of the mid-sagittal plane is important for the assessment and correction of several deformities. Furthermore, the mid-sagittal plane can be used for the definition of standardized coordinate systems such as pelvis or skull coordinate systems. A popular approach for mid-sagittal plane computation is based on the selection of anatomical landmarks located either directly on the plane or symmetrically to it. However, the manual selection of landmarks is a tedious, time-consuming and error-prone task, which requires great care. In order to overcome this drawback, previously it was suggested to use the iterative closest point (ICP) algorithm: After an initial mirroring of the data points on a default mirror plane, the mirrored data points should be registered iteratively to the model points using rigid transforms. Finally, a reflection transform approximating the cumulative transform could be extracted. In this work, we present an ICP variant for the iterative optimization of the reflection parameters. It is based on a closed-form solution to the least-squares problem of matching data points to model points using a reflection. In experiments on CT pelvis and skull datasets our method showed a better ability to match homologous areas.

Space Weather Model Testing And Validation At The Community Coordinated Modeling Center

NASA Astrophysics Data System (ADS)

Hesse, M.; Kuznetsova, M.; Rastaetter, L.; Falasca, A.; Keller, K.; Reitan, P.

The Community Coordinated Modeling Center (CCMC) is a multi-agency partner- ship aimed at the creation of next generation space weather models. The goal of the CCMC is to undertake the research and developmental work necessary to substantially increase the present-day modeling capability for space weather purposes, and to pro- vide models for transition to the rapid prototyping centers at the space weather forecast centers. This goal requires close collaborations with and substantial involvement of the research community. The physical regions to be addressed by CCMC-related activities range from the solar atmosphere to the Earth's upper atmosphere. The CCMC is an integral part of NASA's Living With aStar initiative, of the National Space Weather Program Implementation Plan, and of the Department of Defense Space Weather Tran- sition Plan. CCMC includes a facility at NASA Goddard Space Flight Center, as well as distributed computing facilities provided by the Air Force. CCMC also provides, to the research community, access to state-of-the-art space research models. In this paper we will provide updates on CCMC status, on current plans, research and devel- opment accomplishments and goals, and on the model testing and validation process undertaken as part of the CCMC mandate.

Lowest-energy structures of (C60)nX (X=Li+,Na+,K+,Cl-) and (C60)nYCl (Y=Li,Na,K) clusters for n

PubMed

Hernández-Rojas, J; Bretón, J; Gomez Llorente, J M; Wales, D J

2004-12-22

Basin-hopping global optimization is used to find likely candidates for the lowest minima on the potential energy surface of (C(60))(n)X (X=Li(+),Na(+),K(+),Cl(-)) and (C(60))(n)YCl (Y=Li,Na,K) clusters with n

NASA Processes and Requirements for Conducting Human-in-the-Loop Closed Chamber Tests

NASA Technical Reports Server (NTRS)

Barta, Daniel J.; Montz, Michael E.

2004-01-01

NASA has specific processes and requirements that must be followed for tests involving human subjects to be conducted in a safe and effective manner. There are five distinct phases of test operations. Phase one, the test request phase, consists of those activities related to initiating, processing, reviewing, and evaluating the test request. Phase two, the test preparation phase consists of those activities related to planning, coordinating, documenting, and building up the test. Phase three, the test readiness phase consists of those activities related to verifying and reviewing the planned test operations. Phase four, the test activity phase, consists of all pretest operations, functional checkouts, emergency drills, and test operations. Phase five, the post test activity phase, consists of those activities performed once the test is completed, including briefings, documentation of anomalies, data reduction and archiving, and reporting. Project management processes must be followed for facility modifications and major test buildup, which include six phases: initiation and assessment, requirements evaluation, preliminary design, detailed design, use readiness review (URR) and acceptance. Compliance with requirements for safety and quality assurance are documented throughout the test buildup and test operation processes. Tests involving human subjects must be reviewed by the applicable Institutional Review Board (IRB).

Conformal Geometry, Hotine’s Conjecture, and Differential Geodesy.

DTIC Science & Technology

1987-07-27

ellipsoid (Stokes Theorem). Rayleigh and Poincare extensively studied tides. Starting around 1900 the close connection between geodesy and mathematics...locally conformal maps on neighborhoods of M ,.’ P -a ,r r’ " % "% J and M’ For example, consider the 2-sphere S and the plane E It 2 2 is well...coordinates where the coordinate surfaces are respectively planes ; planes and cylinders; and planes , spheres, - and cones. we give one less trivial example

Streamlining Collaborative Planning in Spacecraft Mission Architectures

NASA Technical Reports Server (NTRS)

Misra, Dhariti; Bopf, Michel; Fishman, Mark; Jones, Jeremy; Kerbel, Uri; Pell, Vince

2000-01-01

During the past two decades, the planning and scheduling community has substantially increased the capability and efficiency of individual planning and scheduling systems. Relatively recently, research work to streamline collaboration between planning systems is gaining attention. Spacecraft missions stand to benefit substantially from this work as they require the coordination of multiple planning organizations and planning systems. Up to the present time this coordination has demanded a great deal of human intervention and/or extensive custom software development efforts. This problem will become acute with increased requirements for cross-mission plan coordination and multi -spacecraft mission planning. The Advanced Architectures and Automation Branch of NASA's Goddard Space Flight Center is taking innovative steps to define collaborative planning architectures, and to identify coordinated planning tools for Cross-Mission Campaigns. Prototypes are being developed to validate these architectures and assess the usefulness of the coordination tools by the planning community. This presentation will focus on one such planning coordination too], named Visual Observation Layout Tool (VOLT), which is currently being developed to streamline the coordination between astronomical missions

45 CFR 1340.4 - Coordination requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT PROGRAM CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT General Provisions § 1340.4 Coordination requirements. All Federal agencies responsible for programs related to child...

47 CFR 25.111 - Additional information.

Code of Federal Regulations, 2010 CFR

2010-10-01

... information it requires for the Advance Publication, Coordination and Notification of frequency assignments... information required by the ITU Radiocommunication Bureau to advance publish, coordinate and notify the frequencies to be used for tracking, telemetry and control functions of DBS systems. [56 FR 24016, May 28...

45 CFR 1340.4 - Coordination requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT PROGRAM CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT General Provisions § 1340.4 Coordination requirements. All Federal agencies responsible for programs related to child...

45 CFR 1340.4 - Coordination requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT PROGRAM CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT General Provisions § 1340.4 Coordination requirements. All Federal agencies responsible for programs related to child...

45 CFR 1340.4 - Coordination requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT PROGRAM CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT General Provisions § 1340.4 Coordination requirements. All Federal agencies responsible for programs related to child...

45 CFR 1340.4 - Coordination requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT PROGRAM CHILD ABUSE AND NEGLECT PREVENTION AND TREATMENT General Provisions § 1340.4 Coordination requirements. All Federal agencies responsible for programs related to child...

75 FR 52944 - Sunshine Act Notices

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-30

... be closed to the public. Items To Be Discussed: Compliance matters pursuant to 2 U.S.C. 437g. Audits...., of Perkins Coie, LLP. Explanation and Justification and Final Rules on Coordinated Communications...

Effects of relational coordination among colleagues and span of control on work engagement among home-visiting nurses.

PubMed

Naruse, Takashi; Sakai, Mahiro; Nagata, Satoko

2016-04-01

Home-visiting nursing agencies are required to foster staff nurse's work engagement; thus, the factors related to work engagement require identification. This study examined relational coordination among colleagues and agency span of control on the work engagement of home-visiting nurses. Cross-sectional data from 93 staff nurses in 31 home-visiting nursing agencies were collected via a survey and analyzed using mixed linear regression. There was no significant main effect of relational coordination among nurse colleagues on work engagement. In large agencies with a large span of control, relational coordination among nursing colleagues predicted work engagement. Nursing managers' relational coordination was found to be positively associated with staff nurse work engagement. Agency span of control is a moderating factor on the positive effect of relational coordination with nursing colleagues on staff nurse work engagement. © 2016 Japan Academy of Nursing Science.

Three dimensional adaptive mesh refinement on a spherical shell for atmospheric models with lagrangian coordinates

NASA Astrophysics Data System (ADS)

Penner, Joyce E.; Andronova, Natalia; Oehmke, Robert C.; Brown, Jonathan; Stout, Quentin F.; Jablonowski, Christiane; van Leer, Bram; Powell, Kenneth G.; Herzog, Michael

2007-07-01

One of the most important advances needed in global climate models is the development of atmospheric General Circulation Models (GCMs) that can reliably treat convection. Such GCMs require high resolution in local convectively active regions, both in the horizontal and vertical directions. During previous research we have developed an Adaptive Mesh Refinement (AMR) dynamical core that can adapt its grid resolution horizontally. Our approach utilizes a finite volume numerical representation of the partial differential equations with floating Lagrangian vertical coordinates and requires resolving dynamical processes on small spatial scales. For the latter it uses a newly developed general-purpose library, which facilitates 3D block-structured AMR on spherical grids. The library manages neighbor information as the blocks adapt, and handles the parallel communication and load balancing, freeing the user to concentrate on the scientific modeling aspects of their code. In particular, this library defines and manages adaptive blocks on the sphere, provides user interfaces for interpolation routines and supports the communication and load-balancing aspects for parallel applications. We have successfully tested the library in a 2-D (longitude-latitude) implementation. During the past year, we have extended the library to treat adaptive mesh refinement in the vertical direction. Preliminary results are discussed. This research project is characterized by an interdisciplinary approach involving atmospheric science, computer science and mathematical/numerical aspects. The work is done in close collaboration between the Atmospheric Science, Computer Science and Aerospace Engineering Departments at the University of Michigan and NOAA GFDL.

The influence of asymmetric force requirements on a multi-frequency bimanual coordination task.

PubMed

Kennedy, Deanna M; Rhee, Joohyun; Jimenez, Judith; Shea, Charles H

2017-01-01

An experiment was designed to determine the impact of the force requirements on the production of bimanual 1:2 coordination patterns requiring the same (symmetric) or different (asymmetric) forces when Lissajous displays and goal templates are provided. The Lissajous displays have been shown to minimize the influence of attentional and perceptual constraints allowing constraints related to neural crosstalk to be more clearly observed. Participants (N=20) were randomly assigned to a force condition in which the left or right limb was required to produce more force than the contralateral limb. In each condition participants were required to rhythmically coordinate the pattern of isometric forces in a 1:2 coordination pattern. Participant performed 13 practice trials and 1 test trial per force level. The results indicated that participants were able to effectively coordinate the 1:2 multi-frequency goal patterns under both symmetric and asymmetric force requirements. However, consistent distortions in the force and force velocity time series were observed for one limb that appeared to be associated with the production of force in the contralateral limb. Distortions in the force produced by the left limb occurred regardless of the force requirements of the task (symmetric, asymmetric) or whether the left or right limb had to produce more force than the contralateral limb. However, distinct distortions in the right limb occurred only when the left limb was required to produce 5 times more force than the right limb. These results are consistent with the notion that neural crosstalk can influence both limbs, but may manifest differently for each limb depending on the force requirements of the task. Copyright © 2016 Elsevier B.V. All rights reserved.

Evaluation of jaw and neck muscle activities while chewing using EMG-EMG transfer function and EMG-EMG coherence function analyses in healthy subjects.

PubMed

Ishii, Tomohiro; Narita, Noriyuki; Endo, Hiroshi

2016-06-01

This study aims to quantitatively clarify the physiological features in rhythmically coordinated jaw and neck muscle EMG activities while chewing gum using EMG-EMG transfer function and EMG-EMG coherence function analyses in 20 healthy subjects. The chewing side masseter muscle EMG signal was used as the reference signal, while the other jaw (non-chewing side masseter muscle, bilateral anterior temporal muscles, and bilateral anterior digastric muscles) and neck muscle (bilateral sternocleidomastoid muscles) EMG signals were used as the examined signals in EMG-EMG transfer function and EMG-EMG coherence function analyses. Chewing-related jaw and neck muscle activities were aggregated in the first peak of the power spectrum in rhythmic chewing. The gain in the peak frequency represented the power relationships between jaw and neck muscle activities during rhythmic chewing. The phase in the peak frequency represented the temporal relationships between the jaw and neck muscle activities, while the non-chewing side neck muscle presented a broad range of distributions across jaw closing and opening phases. Coherence in the peak frequency represented the synergistic features in bilateral jaw closing muscles and chewing side neck muscle activities. The coherence and phase in non-chewing side neck muscle activities exhibited a significant negative correlation. From above, the bilateral coordination between the jaw and neck muscle activities is estimated while chewing when the non-chewing side neck muscle is synchronously activated with the jaw closing muscles, while the unilateral coordination is estimated when the non-chewing side neck muscle is irregularly activated in the jaw opening phase. Thus, the occurrence of bilateral or unilateral coordinated features in the jaw and neck muscle activities may correspond to the phase characteristics in the non-chewing side neck muscle activities during rhythmical chewing. Considering these novel findings in healthy subjects, EMG-EMG transfer function and EMG-EMG coherence function analyses may also be useful to diagnose the pathologically in-coordinated features in jaw and neck muscle activities in temporomandibular disorders and whiplash-associated disorders during critical chewing performance. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Remarks towards the spectrum of the Heisenberg spin chain type models

NASA Astrophysics Data System (ADS)

Burdík, Č.; Fuksa, J.; Isaev, A. P.; Krivonos, S. O.; Navrátil, O.

2015-05-01

The integrable close and open chain models can be formulated in terms of generators of the Hecke algebras. In this review paper, we describe in detail the Bethe ansatz for the XXX and the XXZ integrable close chain models. We find the Bethe vectors for two-component and inhomogeneous models. We also find the Bethe vectors for the fermionic realization of the integrable XXX and XXZ close chain models by means of the algebraic and coordinate Bethe ansatz. Special modification of the XXZ closed spin chain model ("small polaron model") is considered. Finally, we discuss some questions relating to the general open Hecke chain models.

Artificial photosynthesis: understanding water splitting in nature

PubMed Central

Cox, Nicholas; Pantazis, Dimitrios A.; Neese, Frank; Lubitz, Wolfgang

2015-01-01

In the context of a global artificial photosynthesis (GAP) project, we review our current work on nature's water splitting catalyst. In a recent report (Cox et al. 2014 Science 345, 804–808 (doi:10.1126/science.1254910)), we showed that the catalyst—a Mn4O5Ca cofactor—converts into an ‘activated’ form immediately prior to the O–O bond formation step. This activated state, which represents an all MnIV complex, is similar to the structure observed by X-ray crystallography but requires the coordination of an additional water molecule. Such a structure locates two oxygens, both derived from water, in close proximity, which probably come together to form the product O2 molecule. We speculate that formation of the activated catalyst state requires inherent structural flexibility. These features represent new design criteria for the development of biomimetic and bioinspired model systems for water splitting catalysts using first-row transition metals with the aim of delivering globally deployable artificial photosynthesis technologies. PMID:26052426

AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis

PubMed Central

Delevoye, Cédric; Hurbain, Ilse; Tenza, Danièle; Sibarita, Jean-Baptiste; Uzan-Gafsou, Stéphanie; Ohno, Hiroshi; Geerts, Willie J.C.; Verkleij, Arie J.; Salamero, Jean; Marks, Michael S.

2009-01-01

Specialized cell types exploit endosomal trafficking to deliver protein cargoes to cell type–specific lysosome-related organelles (LROs), but how endosomes are specified for this function is not known. In this study, we show that the clathrin adaptor AP-1 and the kinesin motor KIF13A together create peripheral recycling endosomal subdomains in melanocytes required for cargo delivery to maturing melanosomes. In cells depleted of AP-1 or KIF13A, a subpopulation of recycling endosomes redistributes to pericentriolar clusters, resulting in sequestration of melanosomal enzymes like Tyrp1 in vacuolar endosomes and consequent inhibition of melanin synthesis and melanosome maturation. Immunocytochemistry, live cell imaging, and electron tomography reveal AP-1– and KIF13A-dependent dynamic close appositions and continuities between peripheral endosomal tubules and melanosomes. Our results reveal that LRO protein sorting is coupled to cell type–specific positioning of endosomes that facilitate endosome–LRO contacts and are required for organelle maturation. PMID:19841138

High level continuity for coordinate generation with precise controls

NASA Technical Reports Server (NTRS)

Eiseman, P. R.

1982-01-01

Coordinate generation techniques with precise local controls have been derived and analyzed for continuity requirements up to both the first and second derivatives, and have been projected to higher level continuity requirements from the established pattern. The desired local control precision was obtained when a family of coordinate surfaces could be uniformly distributed without a consequent creation of flat spots on the coordinate curves transverse to the family. Relative to the uniform distribution, the family could be redistributed from an a priori distribution function or from a solution adaptive approach, both without distortion from the underlying transformation which may be independently chosen to fit a nontrivial geometry and topology.

From Adult Finger Tapping to Fetal Heart Beating: Retracing the Role of Coordination in Constituting Agency.

PubMed

Solfo, Alessandro; van Leeuwen, Cees

2018-01-01

Sense of agency can be defined as the self-awareness of bodily movement, whereas extended agency as the self-awareness of affecting, through movement, events concomitant with movement. As a distinctive manifestation of agency, we review Spizzo's effect. This effect arises when agents coordinate their rhythmic movements with visual pulses. Once coordination is established, agents feel controlling the onset or the offset of the pulses through their movements. Spizzo's effect, therefore, constitutes a manifest case of extended agency, in which agents are aware of controlling, through movement, the pulses temporally concomitant with movement. We propose that sense of agency requires continuity of kinesthesia, which in turn requires the continuity of selfhood. The continuity of kinesthesia is necessarily deduced from the consistent kinematics observed in movements, whereas the continuity of selfhood may stem from the patterns of rhythmic coordination that humans encounter ever since intrauterine life. The primacy of these patterns in adults is in accordance with phenomena such as Spizzo's effect, which require coordination to be induced. We, therefore, propose coordination as the fundamental interaction from which selfhood, kinesthesia, and agency arise. Copyright © 2017 Cognitive Science Society, Inc.

National Tribal Air Association Operations - Closed Announcement FY 2016

EPA Pesticide Factsheets

OAR is seeking applications from eligible entities to provide comprehensive air quality policy and regulatory analysis including support and national coordination activities to assist tribes participation in policy and regulatory activities.

About the Office of Public Engagement and Environmental Education (OPEEE)

EPA Pesticide Factsheets

OPEEE leads and coordinates EPA programs to provide national leadership in promoting environmental literacy and establishes and maintains close working relationships with a broad range of public- and private-sector organizations.

Juno Detects a Ham Radio HI from Earth

NASA Image and Video Library

2013-12-10

During its close flyby of Earth, NASA Jupiter-bound Juno spacecraft listened for a coordinated, global transmission from amateur radio operators using its radio and plasma wave science instrument, known as Waves.

Linking clinician interaction and coordination to clinical performance in Patient-Aligned Care Teams.

PubMed

Hysong, Sylvia J; Thomas, Candice L; Spitzmüller, Christiane; Amspoker, Amber B; Woodard, LeChauncy; Modi, Varsha; Naik, Aanand D

2016-01-15

Team coordination within clinical care settings is a critical component of effective patient care. Less is known about the extent, effectiveness, and impact of coordination activities among professionals within VA Patient-Aligned Care Teams (PACTs). This study will address these gaps by describing the specific, fundamental tasks and practices involved in PACT coordination, their impact on performance measures, and the role of coordination task complexity. First, we will use a web-based survey of coordination practices among 1600 PACTs in the national VHA. Survey findings will characterize PACT coordination practices and assess their association with clinical performance measures. Functional job analysis, using 6-8 subject matter experts who are 3rd and 4th year residents in VA Primary Care rotations, will be utilized to identify the tasks involved in completing clinical performance measures to standard. From this, expert ratings of coordination complexity will be used to determine the level of coordinative complexity required for each of the clinical performance measures drawn from the VA External Peer Review Program (EPRP). For objective 3, data collected from the first two methods will evaluate the effect of clinical complexity on the relationships between measures of PACT coordination and their ratings on the clinical performance measures. Results from this study will support successful implementation of coordinated team-based work in clinical settings by providing knowledge regarding which aspects of care require the most complex levels of coordination and how specific coordination practices impact clinical performance.

Josephin Domain Structural Conformations Explored by Metadynamics in Essential Coordinates

PubMed Central

Tuszynski, Jack A.; Gallo, Diego; Morbiducci, Umberto; Danani, Andrea

2016-01-01

The Josephin Domain (JD), i.e. the N-terminal domain of Ataxin 3 (At3) protein, is an interesting example of competition between physiological function and aggregation risk. In fact, the fibrillogenesis of Ataxin 3, responsible for the spinocerebbellar ataxia 3, is strictly related to the JD thermodynamic stability. Whereas recent NMR studies have demonstrated that different JD conformations exist, the likelihood of JD achievable conformational states in solution is still an open issue. Marked differences in the available NMR models are located in the hairpin region, supporting the idea that JD has a flexible hairpin in dynamic equilibrium between open and closed states. In this work we have carried out an investigation on the JD conformational arrangement by means of both classical molecular dynamics (MD) and Metadynamics employing essential coordinates as collective variables. We provide a representation of the free energy landscape characterizing the transition pathway from a JD open-like structure to a closed-like conformation. Findings of our in silico study strongly point to the closed-like conformation as the most likely for a Josephin Domain in water. PMID:26745628

Meeting the Needs of Children with Medical Complexity Using a Telehealth Advanced Practice Registered Nurse Care Coordination Model

PubMed Central

Erickson, Mary; Lunos, Scott; Finkelstein, Stanley M.; Looman, Wendy; Celebreeze, Margaret; Garwick, Ann

2015-01-01

Effective care coordination is a key quality and safety strategy for populations with chronic conditions, including children with medical complexity (CMC). However, gaps remain in parent report of the need for care coordination help and receipt of care coordination help. New models must close this gap while maintaining family-centered focus. A three-armed randomized controlled trial conducted in an established medical home utilized an advanced practice registered nurse intervention based on Presler’s model of clinic-based care coordination. The model supported families of CMC across settings using telephone only or telephone and video telehealth care coordination. Effectiveness was evaluated from many perspectives and this paper reports on a subset of outcomes that includes family-centered care (FCC), need for care coordination help and adequacy of care coordination help received. FCC at baseline and end of study showed no significant difference between groups. Median FCC scores of 18.0–20.0 across all groups indicated high FCC within the medical home. No significant differences were found in the need for care coordination help within or between groups and over time. No significant difference was found in the adequacy of help received between groups at baseline. However, this indicator increased significantly over time for both intervention groups. These findings suggest that in an established medical home with high levels of FCC, families of CMC have unmet needs for care coordination help that are addressed by the APRN telehealth care coordination model. PMID:25424455

Meeting the needs of children with medical complexity using a telehealth advanced practice registered nurse care coordination model.

PubMed

Cady, Rhonda G; Erickson, Mary; Lunos, Scott; Finkelstein, Stanley M; Looman, Wendy; Celebreeze, Margaret; Garwick, Ann

2015-07-01

Effective care coordination is a key quality and safety strategy for populations with chronic conditions, including children with medical complexity (CMC). However, gaps remain in parent report of the need for care coordination help and receipt of care coordination help. New models must close this gap while maintaining family-centered focus. A three-armed randomized controlled trial conducted in an established medical home utilized an advanced practice registered nurse intervention based on Presler's model of clinic-based care coordination. The model supported families of CMC across settings using telephone only or telephone and video telehealth care coordination. Effectiveness was evaluated from many perspectives and this paper reports on a subset of outcomes that includes family-centered care (FCC), need for care coordination help and adequacy of care coordination help received. FCC at baseline and end of study showed no significant difference between groups. Median FCC scores of 18.0-20.0 across all groups indicated high FCC within the medical home. No significant differences were found in the need for care coordination help within or between groups and over time. No significant difference was found in the adequacy of help received between groups at baseline. However, this indicator increased significantly over time for both intervention groups. These findings suggest that in an established medical home with high levels of FCC, families of CMC have unmet needs for care coordination help that are addressed by the APRN telehealth care coordination model.

Coordination as a function of skill level in the gymnastics longswing.

PubMed

Williams, Genevieve K R; Irwin, Gareth; Kerwin, David G; Hamill, Joseph; Van Emmerik, Richard E A; Newell, Karl M

2016-01-01

The purpose of this study was to investigate the nature of inter-joint coordination at different levels of skilled performance to: (1) distinguish learners who were successful versus unsuccessful in terms of their task performance; (2) investigate the pathways of change during the learning of a new coordination pattern and (3) examine how the learner's coordination patterns relate to those of experts in the longswing gymnastics skill. Continuous relative phase of hip and shoulder joint motions was examined for longswings performed by two groups of novices, successful (n = 4) and unsuccessful (n = 4) over five practice sessions, and two expert gymnasts. Principal component analysis showed that during longswing positions where least continuous relative phase variability occurred for expert gymnasts, high variability distinguished the successful from the unsuccessful novice group. Continuous relative phase profiles of successful novices became more out-of-phase over practice and less similar to the closely in-phase coupling of the expert gymnasts. Collectively, the findings support the proposition that at the level in inter-joint coordination a technique emerges that facilitates successful performance but is not more like an expert's movement coordination. This finding questions the appropriateness of inferring development towards a "gold champion" movement coordination.

Viewpoint Dependent Imaging: An Interactive Stereoscopic Display

NASA Astrophysics Data System (ADS)

Fisher, Scott

1983-04-01

Design and implementation of a viewpoint Dependent imaging system is described. The resultant display is an interactive, lifesize, stereoscopic image. that becomes a window into a three dimensional visual environment. As the user physically changes his viewpoint of the represented data in relation to the display surface, the image is continuously updated. The changing viewpoints are retrieved from a comprehensive, stereoscopic image array stored on computer controlled, optical videodisc and fluidly presented. in coordination with the viewer's, movements as detected by a body-tracking device. This imaging system is an attempt to more closely represent an observers interactive perceptual experience of the visual world by presenting sensory information cues not offered by traditional media technologies: binocular parallax, motion parallax, and motion perspective. Unlike holographic imaging, this display requires, relatively low bandwidth.

A Time History of Control Operation of a C-54 Airplane in Blind Landing Approaches

NASA Technical Reports Server (NTRS)

Talmage, Donald B.

1947-01-01

Tests were made with a C-54 airplane in which airline pilots made several blind approaches to determine whether any special flying techniques were used in blind landings and whether any special handling-qualities requirements would have to be formulated because of such special techniques. It was found that the airplane was flown at all times in the normal manner; that is, all turns were banked turns that were nearly coordinated by use of the rudder so that the sideslip was held close to zero. The pilot expended considerable physical work in continually moving the controls but this wake was due in part to the large friction in the three control systems. The actual control deflections used were small compared to the maximum deflections available.

An Ultra-low-power Medium Access Control Protocol for Body Sensor Network.

PubMed

Li, Huaming; Tan, Jindong

2005-01-01

In this paper, a medium access control (MAC) protocol designed for Body Sensor Network (BSN-MAC) is proposed. BSN-MAC is an adaptive, feedback-based and IEEE 802.15.4-compatible MAC protocol. Due to the traffic coupling and sensor diversity characteristics of BSNs, common MAC protocols can not satisfy the unique requirements of the biomedical sensors in BSN. BSN-MAC exploits the feedback information from the deployed sensors to form a closed-loop control of the MAC parameters. A control algorithm is proposed to enable the BSN coordinator to adjust parameters of the IEEE 802.15.4 superframe to achieve both energy efficiency and low latency on energy critical nodes. We evaluate the performance of BSN-MAC using energy efficiency as the primary metric.

Prediction of high-speed rotor noise with a Kirchhoff formula

NASA Technical Reports Server (NTRS)

Purcell, Timothy W.; Strawn, Roger C.; Yu, Yung H.

1987-01-01

A new methodology has been developed to predict the impulsive noise generated by a transonic rotor blade. The formulation uses a full-potential finite-difference method to obtain the pressure field close to the blade. A Kirchhoff integral formulation is then used to extend these finite-difference results into the far-field. This Kirchhoff formula is written in a blade-fixed coordinate system. It requires initial data across a plane at the sonic radius. This data is provided by the finite-difference solution. Acoustic pressure predictions show excellent agreement with hover experimental data for two hover cases of 0.88 and 0.90 tip Mach number, the latter of which has delocalized transonic flow. These results represent the first successful prediction technique for peak pressure amplitudes using a computational code.

Simplifying and speeding the management of intra-node cache coherence

DOEpatents

Blumrich, Matthias A [Ridgefield, CT; Chen, Dong [Croton on Hudson, NY; Coteus, Paul W [Yorktown Heights, NY; Gara, Alan G [Mount Kisco, NY; Giampapa, Mark E [Irvington, NY; Heidelberger, Phillip [Cortlandt Manor, NY; Hoenicke, Dirk [Ossining, NY; Ohmacht, Martin [Yorktown Heights, NY

2012-04-17

A method and apparatus for managing coherence between two processors of a two processor node of a multi-processor computer system. Generally the present invention relates to a software algorithm that simplifies and significantly speeds the management of cache coherence in a message passing parallel computer, and to hardware apparatus that assists this cache coherence algorithm. The software algorithm uses the opening and closing of put/get windows to coordinate the activated required to achieve cache coherence. The hardware apparatus may be an extension to the hardware address decode, that creates, in the physical memory address space of the node, an area of virtual memory that (a) does not actually exist, and (b) is therefore able to respond instantly to read and write requests from the processing elements.

Implant support for removable partial overdentures: a case report.

PubMed

Halterman, S M; Rivers, J A; Keith, J D; Nelson, D R

1999-01-01

Functional stability and the preservation of remaining alveolar bone are primary, and often elusive, goals when restoring the partially edentulous arch. The incorporation of dental implants for the partial support of removable prostheses offers a practical adjunct in the fulfillment of these objectives. Planning for complex courses of treatment that include dental implants requires close coordination between the surgeon and the restorative dentist. Decisions that deal with type, location, size, number of implant fixtures, and design of the prosthesis are critical. All of these areas must be discussed and established as acceptable to the patient and each clinician before the initiation of treatment. In this report, we present a course of patient treatment in which a removable partial denture is supported by natural remaining teeth in conjunction with osseointegrated implants.

Managing coherence via put/get windows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blumrich, Matthias A; Chen, Dong; Coteus, Paul W

A method and apparatus for managing coherence between two processors of a two processor node of a multi-processor computer system. Generally the present invention relates to a software algorithm that simplifies and significantly speeds the management of cache coherence in a message passing parallel computer, and to hardware apparatus that assists this cache coherence algorithm. The software algorithm uses the opening and closing of put/get windows to coordinate the activated required to achieve cache coherence. The hardware apparatus may be an extension to the hardware address decode, that creates, in the physical memory address space of the node, an areamore » of virtual memory that (a) does not actually exist, and (b) is therefore able to respond instantly to read and write requests from the processing elements.« less

Enhancing automatic closed-loop glucose control in type 1 diabetes with an adaptive meal bolus calculator - in silico evaluation under intra-day variability.

PubMed

Herrero, Pau; Bondia, Jorge; Adewuyi, Oloruntoba; Pesl, Peter; El-Sharkawy, Mohamed; Reddy, Monika; Toumazou, Chris; Oliver, Nick; Georgiou, Pantelis

2017-07-01

Current prototypes of closed-loop systems for glucose control in type 1 diabetes mellitus, also referred to as artificial pancreas systems, require a pre-meal insulin bolus to compensate for delays in subcutaneous insulin absorption in order to avoid initial post-prandial hyperglycemia. Computing such a meal bolus is a challenging task due to the high intra-subject variability of insulin requirements. Most closed-loop systems compute this pre-meal insulin dose by a standard bolus calculation, as is commonly found in insulin pumps. However, the performance of these calculators is limited due to a lack of adaptiveness in front of dynamic changes in insulin requirements. Despite some initial attempts to include adaptation within these calculators, challenges remain. In this paper we present a new technique to automatically adapt the meal-priming bolus within an artificial pancreas. The technique consists of using a novel adaptive bolus calculator based on Case-Based Reasoning and Run-To-Run control, within a closed-loop controller. Coordination between the adaptive bolus calculator and the controller was required to achieve the desired performance. For testing purposes, the clinically validated Imperial College Artificial Pancreas controller was employed. The proposed system was evaluated against itself but without bolus adaptation. The UVa-Padova T1DM v3.2 system was used to carry out a three-month in silico study on 11 adult and 11 adolescent virtual subjects taking into account inter-and intra-subject variability of insulin requirements and uncertainty on carbohydrate intake. Overall, the closed-loop controller enhanced by an adaptive bolus calculator improves glycemic control when compared to its non-adaptive counterpart. In particular, the following statistically significant improvements were found (non-adaptive vs. adaptive). Adults: mean glucose 142.2 ± 9.4vs. 131.8 ± 4.2mg/dl; percentage time in target [70, 180]mg/dl, 82.0 ± 7.0vs. 89.5 ± 4.2; percentage time above target 17.7 ± 7.0vs. 10.2 ± 4.1. Adolescents: mean glucose 158.2 ± 21.4vs. 140.5 ± 13.0mg/dl; percentage time in target, 65.9 ± 12.9vs. 77.5 ± 12.2; percentage time above target, 31.7 ± 13.1vs. 19.8 ± 10.2. Note that no increase in percentage time in hypoglycemia was observed. Using an adaptive meal bolus calculator within a closed-loop control system has the potential to improve glycemic control in type 1 diabetes when compared to its non-adaptive counterpart. Copyright © 2017 Elsevier B.V. All rights reserved.

32 CFR 555.10 - Coordination requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 3 2013-07-01 2013-07-01 false Coordination requirements. 555.10 Section 555.10 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY MILITARY RESERVATIONS AND... be reported to the designated POC in the Principal Laboratory, with a copy of the notification to...

Emergence of multiple synchronization modes in hydrodynamically-coupled cilia

NASA Astrophysics Data System (ADS)

Guo, Hanliang; Kanso, Eva

2016-11-01

Motile cilia and flagella exhibit different phase coordinations. For example, closely swimming spermatozoa are observed to synchronize together; bi-flagellates Chlamydomonas regulate the flagella in a "breast-stroke" fashion; cilia on the surface of Paramecium beat in a fixed phase lag in an orchestrated wave like fashion. Experimental evidence suggests that phase coordinations can be achieved solely via hydrodynamical interactions. However, the exact mechanisms behind it remain illusive. Here, adapting a "geometric switch" model, we observe different synchronization modes in pairs of hydrodynamically-coupled cilia by changing physical parameters such as the strength of the cilia internal motor and the separation distance between cilia. Interestingly, we find regions in the parameter space where the coupled cilia reach stable phase coordinations and regions where the phase coordinations are sensitive to perturbations. We also find that leaning into the fluid reduces the sensitivity to perturbations, and produces stable phase coordination that is neither in-phase nor anti-phase, which could explain the origin of metachronal waves in large cilia populations.

Conversion of the high-mode solitons in strongly nonlocal nonlinear media

NASA Astrophysics Data System (ADS)

Zhang, Xiaping

2017-01-01

The conversion of high-mode solitons propagating in Strongly Nonlocal Nonlinear Media (SNNM) in three coordinate systems, namely, the elliptic coordinate system, the rectangular coordinate system and the cylindrical coordinate system, based on the Snyder-Mitchell Model that describes the paraxial beam propagating in SNNM, is discussed. Through constituting the trial solution with modulating the Gaussian beam by Ince polynomials, the closed-solution of Gaussian beams in elliptic coordinate is accessed. The Ince-Gaussian (IG) beams constitute the exact and continuous transition modes between Hermite-Gaussian beams and Laguerre-Gaussian (LG) beams, which is controlled by the elliptic parameter. The conditions of conversion in the three types of solitons are given in relation to the Gouy phase invariability in stable propagation. The profiles of the IG breather at a different propagating distance are numerically obtained, and the conversions of a few IG solitons are illustrated. The difference between the IG soliton and the corresponding LG soliton is remarkable from the Poynting vector and phase plots at their profiles along the propagating axis.

Defect in the Joint Spectrum of Hydrogen due to Monodromy.

PubMed

Dullin, Holger R; Waalkens, Holger

2018-01-12

In addition to the well-known case of spherical coordinates, the Schrödinger equation of the hydrogen atom separates in three further coordinate systems. Separating in a particular coordinate system defines a system of three commuting operators. We show that the joint spectrum of the Hamilton operator, the z component of the angular momentum, and an operator involving the z component of the quantum Laplace-Runge-Lenz vector obtained from separation in prolate spheroidal coordinates has quantum monodromy for energies sufficiently close to the ionization threshold. The precise value of the energy above which monodromy is observed depends on the distance of the focus points of the spheroidal coordinates. The presence of monodromy means that one cannot globally assign quantum numbers to the joint spectrum. Whereas the principal quantum number n and the magnetic quantum number m correspond to the Bohr-Sommerfeld quantization of globally defined classical actions a third quantum number cannot be globally defined because the third action is globally multivalued.

Possibility of exchange of a rectilinear three-body system with zero energy

NASA Astrophysics Data System (ADS)

Koda, Eiji

The possibility of exchange for a rectilinear three-body system with zero energy is examined by introducing regularized coordinates which are closely related to McGehee's (1974) coordinates. It is shown that all of the HE(-)-HE(+) orbits are of exchange type in a critical system whose orbits of parabolic-parabolic escape type experience odd times of binary collision. No exchange occurs in critical systems whose orbits of parabolic-parabolic escape type experience even times of binary collision.

Photogrammetry: An available surface characterization tool for solar concentrators. Part 1: Measurements of surfaces

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shortis, M.R.; Johnston, G.H.G.

1996-08-01

Close range photogrammetry is a sensing technique that allows the three-dimensional coordinates of selected points on a surface of almost any dimension and orientation to be assessed. Surface characterizations of paraboloidal reflecting surfaces at the ANU using photogrammetry have indicated that three-dimensional coordinate precisions approach 1:20,000 are readily achievable using this technique. This allows surface quality assessments to be made of large solar collecting devices with a precision that is difficult to achieve with other methods.

48 CFR 970.5223-7 - Sustainable acquisition program.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Environmental Sustainability Coordinator or equivalent position. (g) The Contractor shall prepare and submit... Sustainability Coordinator at the supported facility. The Subcontractor will advise the Contractor if it is... coordinate its activities with and submit required reports through the Environmental Sustainability...

48 CFR 970.5223-7 - Sustainable acquisition program.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Environmental Sustainability Coordinator or equivalent position. (g) The Contractor shall prepare and submit... Sustainability Coordinator at the supported facility. The Subcontractor will advise the Contractor if it is... coordinate its activities with and submit required reports through the Environmental Sustainability...

48 CFR 970.5223-7 - Sustainable acquisition program.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Environmental Sustainability Coordinator or equivalent position. (g) The Contractor shall prepare and submit... Sustainability Coordinator at the supported facility. The Subcontractor will advise the Contractor if it is... coordinate its activities with and submit required reports through the Environmental Sustainability...

48 CFR 970.5223-7 - Sustainable acquisition program.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Environmental Sustainability Coordinator or equivalent position. (g) The Contractor shall prepare and submit... Sustainability Coordinator at the supported facility. The Subcontractor will advise the Contractor if it is... coordinate its activities with and submit required reports through the Environmental Sustainability...

Generations of orthogonal surface coordinates

NASA Technical Reports Server (NTRS)

Blottner, F. G.; Moreno, J. B.

1980-01-01

Two generation methods were developed for three dimensional flows where the computational domain normal to the surface is small. With this restriction the coordinate system requires orthogonality only at the body surface. The first method uses the orthogonal condition in finite-difference form to determine the surface coordinates with the metric coefficients and curvature of the coordinate lines calculated numerically. The second method obtains analytical expressions for the metric coefficients and for the curvature of the coordinate lines.

National Tribal Air Association Operations Grant - Closed Announcement FY 2013

EPA Pesticide Factsheets

EPA cooperative agreement to strengthen tribal air programs in order to enhance communication and coordination on policy and regulatory activities between federally recognized tribes, EPA, and Indian tribes and Alaska Native Villages.

36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

Code of Federal Regulations, 2011 CFR

2011-07-01

... OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.6 Coordination with requirements under the... Policy Act apply to the effect that the project will have on the human environment. To the extent that... Environmental Impact Statement (EIS) subject to the time requirements for a draft and final EIS, in which case...

36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

Code of Federal Regulations, 2014 CFR

2014-07-01

... OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.6 Coordination with requirements under the... Policy Act apply to the effect that the project will have on the human environment. To the extent that... Environmental Impact Statement (EIS) subject to the time requirements for a draft and final EIS, in which case...

36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

Code of Federal Regulations, 2012 CFR

2012-07-01

... OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.6 Coordination with requirements under the... Policy Act apply to the effect that the project will have on the human environment. To the extent that... Environmental Impact Statement (EIS) subject to the time requirements for a draft and final EIS, in which case...

36 CFR 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

Code of Federal Regulations, 2010 CFR

2010-07-01

... OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.6 Coordination with requirements under the... Policy Act apply to the effect that the project will have on the human environment. To the extent that... Environmental Impact Statement (EIS) subject to the time requirements for a draft and final EIS, in which case...

36 CFR § 801.6 - Coordination with requirements under the National Environmental Policy Act (42 U.S.C. 4321 et seq.).

Code of Federal Regulations, 2013 CFR

2013-07-01

... OF THE URBAN DEVELOPMENT ACTION GRANT PROGRAM § 801.6 Coordination with requirements under the... Policy Act apply to the effect that the project will have on the human environment. To the extent that... Environmental Impact Statement (EIS) subject to the time requirements for a draft and final EIS, in which case...

An immediate effect of custom-made ankle foot orthoses on postural stability in older adults.

PubMed

Yalla, Sai V; Crews, Ryan T; Fleischer, Adam E; Grewal, Gurtej; Ortiz, Jacque; Najafi, Bijan

2014-12-01

Foot and ankle problems are highly prevalent fall risks in the elderly. Ankle foot orthoses designed to stabilize the foot and ankles have been studied within specific patient groups, but their efficacy with a less restrictive elderly population is unknown. This study investigated if custom-made ankle foot orthoses improve postural stability in older adults. Thirty ambulatory older adults averaged 73 (standard deviation=6.5) years completed Romberg's balance (eyes-open/eyes-closed), functional reach, and Timed Up and Go tests while wearing validated kinematic sensors. Each test was completed in standardized shoes with and without bilateral orthoses. Additionally, barefoot trials were conducted for the Romberg's and functional reach tests. Compared to the barefoot and 'shoes alone' conditions, the orthoses reduced center of mass sway on average by 49.0% (P=0.087) and 40.7% (P=0.005) during eyes-open balance trials. The reduction was amplified during the eyes-closed trials with average reductions of 65.9% (P=0.000) and 47.8% (P=0.004), compared to barefoot and 'shoes alone' conditions. The orthoses did not limit functional reach distance nor timed-up and go completion times. However, the medial-lateral postural coordination while reaching was improved significantly with orthoses compared to barefoot (14.3%; P=0.030) and 'shoes alone' (13.5%; P=0.039) conditions. Ankle foot orthoses reduced postural sway and improved lower extremity coordination in the elderly participants without limiting their ability to perform a standard activity of daily living. Additional studies are required to determine if these benefits are retained and subsequently translate into fewer falls. Copyright © 2014. Published by Elsevier Ltd.

Configurational and constitutional information storage: multiple dynamics in systems based on pyridyl and acyl hydrazones.

PubMed

Chaur, Manuel N; Collado, Daniel; Lehn, Jean-Marie

2011-01-03

The C=N group of hydrazones can undergo E/Z isomerization both photochemically and thermally, allowing the generation of a closed process that can be tuned by either of these two physical stimuli. On the other hand, hydrazine-exchange reactions enable a constitutional change in a given hydrazone. The two classes of processes: 1) configurational (physically stimulated) and 2) constitutional (chemically stimulated) give access to short-term and long-term information storage, respectively. Such transformations are reported herein for two hydrazones (bis-pyridyl hydrazone and 2-pyridinecarboxaldehyde phenylhydrazone) that undergo a closed, chemically or physically driven process, and, in addition, can be locked or unlocked at will by metal-ion coordination or removal. These features also extend to acyl hydrazones derived from 2-pyridinecarboxaldehyde. Similarly to the terpydine-like hydrazones, such acyl hydrazones can undergo both constitutional and configurational changes, as well as metal-ion coordination. All these types of hydrazones represent dynamic systems capable of acting as multiple state molecular devices, in which the presence of coordination sites furthermore allows the metal ion-controlled locking and unlocking of the interconversion of the different states. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

34 CFR 364.26 - What are the requirements for cooperation, coordination, and working relationships?

Code of Federal Regulations, 2010 CFR

2010-07-01

... EDUCATION STATE INDEPENDENT LIVING SERVICES PROGRAM AND CENTERS FOR INDEPENDENT LIVING PROGRAM: GENERAL... 34 Education 2 2010-07-01 2010-07-01 false What are the requirements for cooperation, coordination, and working relationships? 364.26 Section 364.26 Education Regulations of the Offices of the...

34 CFR 364.26 - What are the requirements for cooperation, coordination, and working relationships?

Code of Federal Regulations, 2011 CFR

2011-07-01

... EDUCATION STATE INDEPENDENT LIVING SERVICES PROGRAM AND CENTERS FOR INDEPENDENT LIVING PROGRAM: GENERAL... 34 Education 2 2011-07-01 2010-07-01 true What are the requirements for cooperation, coordination, and working relationships? 364.26 Section 364.26 Education Regulations of the Offices of the...

10 CFR 1021.341 - Coordination with other environmental review requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... environmental review requirements. (a) In accordance with 40 CFR 1500.4(k) and (o), 1502.25, and 1506.4, DOE shall integrate the NEPA process and coordinate NEPA compliance with other environmental review... agencies when necessary or appropriate, to ensure compliance and to avoid delays, and shall incorporate any...

Roadside Judgments in Children with Developmental Co-ordination Disorder

ERIC Educational Resources Information Center

Purcell, Catherine; Wann, John P.; Wilmut, Kate; Poulter, Damian

2011-01-01

As pedestrians, the perceptual ability to accurately judge the relative rate of approaching vehicles and select a suitable crossing gap requires sensitivity to looming. It also requires that crossing judgments are synchronized with motoric capabilities. Previous research has suggested that children with Developmental Co-ordination Disorder (DCD)…

47 CFR 27.73 - WCS, AMT, and Goldstone coordination requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... requirements. 27.73 Section 27.73 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON... must cooperate in good faith in the coordination and deployment of new facilities. WCS licensees must also cooperate in good faith in the selection and use of new station sites and new frequencies when...

47 CFR 27.73 - WCS, AMT, and Goldstone coordination requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... requirements. 27.73 Section 27.73 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON... must cooperate in good faith in the coordination and deployment of new facilities. WCS licensees must also cooperate in good faith in the selection and use of new station sites and new frequencies when...

(De)stabilization of Required and Spontaneous Postural Dynamics with Learning

ERIC Educational Resources Information Center

Faugloire, Elise; Bardy, Benoit G.; Stoffregen, Thomas A.

2009-01-01

The present research examined how learning a new ankle-hip coordination influenced the preexisting postural repertoire. Standing participants learned a new ankle-hip coordination mode (relative phase of 90[degrees]). Before and after practice, postural patterns were evaluated in two different tasks. In the required task, specific ankle-hip…

44 CFR 5.22 - Coordination of publication.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Coordination of publication..., DEPARTMENT OF HOMELAND SECURITY GENERAL PRODUCTION OR DISCLOSURE OF INFORMATION Publication of or... of publication. The Chief Counsel, FEMA, is responsible for coordination of FEMA materials required...

44 CFR 5.22 - Coordination of publication.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Coordination of publication..., DEPARTMENT OF HOMELAND SECURITY GENERAL PRODUCTION OR DISCLOSURE OF INFORMATION Publication of or... of publication. The Chief Counsel, FEMA, is responsible for coordination of FEMA materials required...

Coordinated Flexibility: How Initial Gaze Position Modulates Eye-Hand Coordination and Reaching

ERIC Educational Resources Information Center

Adam, Jos J.; Buetti, Simona; Kerzel, Dirk

2012-01-01

Reaching to targets in space requires the coordination of eye and hand movements. In two experiments, we recorded eye and hand kinematics to examine the role of gaze position at target onset on eye-hand coordination and reaching performance. Experiment 1 showed that with eyes and hand aligned on the same peripheral start location, time lags…

Jaw-phonatory coordination in chronic developmental stuttering.

PubMed

Loucks, Torrey M J; De Nil, Luc F; Sasisekaran, Jayanthi

2007-01-01

A deficiency in sensorimotor integration in a person who stutters may be a factor in the pathophysiology of developmental stuttering. To test oral sensorimotor function in adults who stutter, we used a task that requires the coordination of a jaw-opening movement with phonation onset. The task was adapted from previous limb coordination studies, which show that movement coordination depends on intact proprioception. We hypothesized that adult stutterers would show deficient jaw-phonatory coordination relative to control participants. The task required initiation of phonation as a jaw-opening movement passed through a narrow spatial target. Target amplitude and jaw movement speed were varied. The stuttering group showed significantly higher movement error and spatial variability in jaw-phonatory coordination compared to the control group, but group differences in movement velocity or duration were not found. The aberrant jaw-phonatory coordination of the stuttering participants suggests that stuttering is associated with an oral proprioceptive limitation, although, the findings are also consistent with a motor control deficit. As a result of this activity, reader will (1) learn about a hypothesis and evidence supporting the view that a sensorimotor deficit contributes to chronic developmental stuttering and (2) will obtain information about the role of proprioception in multi-articulatory coordination and how it can be tested using an oral-phonatory coordination task.

40 CFR 123.3 - Coordination with other programs.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Coordination with other programs. 123.3 Section 123.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS STATE PROGRAM REQUIREMENTS General § 123.3 Coordination with other programs. Issuance of State permits...

40 CFR 123.3 - Coordination with other programs.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Coordination with other programs. 123.3 Section 123.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS STATE PROGRAM REQUIREMENTS General § 123.3 Coordination with other programs. Issuance of State permits...

40 CFR 123.3 - Coordination with other programs.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Coordination with other programs. 123.3 Section 123.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS STATE PROGRAM REQUIREMENTS General § 123.3 Coordination with other programs. Issuance of State permits...

The roles of categorical and coordinate spatial relations in recognizing buildings.

PubMed

Palermo, Liana; Piccardi, Laura; Nori, Raffaella; Giusberti, Fiorella; Guariglia, Cecilia

2012-11-01

Categorical spatial information is considered more useful for recognizing objects, and coordinate spatial information for guiding actions--for example, during navigation or grasping. In contrast with this assumption, we hypothesized that buildings, unlike other categories of objects, require both categorical and coordinate spatial information in order to be recognized. This hypothesis arose from evidence that right-brain-damaged patients have deficits in both coordinate judgments and recognition of buildings and from the fact that buildings are very useful for guiding navigation in urban environments. To test this hypothesis, we assessed 210 healthy college students while they performed four different tasks that required categorical and coordinate judgments and the recognition of common objects and buildings. Our results showed that both categorical and coordinate spatial representations are necessary to recognize a building, whereas only categorical representations are necessary to recognize an object. We discuss our data in view of a recent neural framework for visuospatial processing, suggesting that recognizing buildings may specifically activate the parieto-medial-temporal pathway.

Sharing resources, coordinating response : deploying and operating incident management systems

DOT National Transportation Integrated Search

1999-01-05

This brochure describes how cost-effective incident management technologies can be useful in handling traffic congestion. Embedded sensors, closed circuit television cameras, and variable message signs are examples of existing technologies that can b...

Timing issues for traffic signals interconnected with highway-railroad grade crossings.

DOT National Transportation Integrated Search

2013-02-01

The coordination of highway-railroad grade crossing warning signals with nearby traffic signals is of vital : importance due to potential safety consequences. Interconnections between traffic signals in close : proximity to railroad crossings provide...

Mithras Studies of the Boundary Between Open and Closed Field Lines.

DTIC Science & Technology

1994-01-31

I ¸ . . A- : - Final Report • March 1995 MITHRAS STUDIES OF THE BOUNDARY BETWEEN OPEN AND CLOSED FIELD LINES John D. Kelly, Program Manager Richard A...Kelly, Program Manager Richard A. Doe, Research Physicist Geoscience and Engineering Center SRI Project 3245 Prepared for: Department of the Air...characteristic energy, energy flux, and an estimate for upward field-aligned current. On the basis of coordinated radar/optical experiments, Vallance Jones et al

Disturbed jaw behavior in whiplash-associated disorders during rhythmic jaw movements.

PubMed

Häggman-Henrikson, B; Zafar, H; Eriksson, P-O

2002-11-01

As shown previously, "functional jaw movements" are the result of coordinated activation of jaw as well as neck muscles, leading to simultaneous movements in the temporomandibular, atlanto-occipital, and cervical spine joints. In this study, the effect of neck trauma on natural jaw function was evaluated in 12 individuals suffering from whiplash-associated disorders (WAD). Spatiotemporal characteristics of mandibular and concomitant head movements were evaluated for three different modes of rhythmic jaw activities: self-paced continuous maximal jaw-opening/-closing movements, paced continuous maximal jaw-opening/-closing movements at 50 cycles/minute, and unilateral chewing. Compared with healthy subjects, the WAD group showed smaller magnitude and altered coordination pattern (a change in temporal relations) of mandibular and head movements. In conclusion, these results show that neck trauma can derange integrated jaw and neck behavior, and underline the functional coupling between the jaw and head-neck motor systems.

Flat connections in open string mirror symmetry

NASA Astrophysics Data System (ADS)

Alim, Murad; Hecht, Michael; Jockers, Hans; Mayr, Peter; Mertens, Adrian; Soroush, Masoud

2012-06-01

We study a flat connection defined on the open-closed deformation space of open string mirror symmetry for type II compactifications on Calabi-Yau threefolds with D-branes. We use flatness and integrability conditions to define distinguished flat coordinates and the superpotential function at an arbitrary point in the open-closed deformation space. Integrability conditions are given for concrete deformation spaces with several closed and open string deformations. We study explicit examples for expansions around different limit points, including orbifold Gromov-Witten invariants, and brane configurations with several brane moduli. In particular, the latter case covers stacks of parallel branes with non-Abelian symmetry.

45 CFR 162.1802 - Standards for coordination of benefits information transaction.

Code of Federal Regulations, 2012 CFR

2012-10-01

....) (ii) The ASC X12 Standards for Electronic Data Interchange Technical Report Type 3—Health Care Claim... DATA STANDARDS AND RELATED REQUIREMENTS ADMINISTRATIVE REQUIREMENTS Coordination of Benefits § 162.1802....1) for the NCPDP Data Record in the Detail Data Record. (Incorporated by reference in § 162.920). (2...

45 CFR 162.1802 - Standards for coordination of benefits information transaction.

Code of Federal Regulations, 2011 CFR

2011-10-01

....) (ii) The ASC X12 Standards for Electronic Data Interchange Technical Report Type 3—Health Care Claim... DATA STANDARDS AND RELATED REQUIREMENTS ADMINISTRATIVE REQUIREMENTS Coordination of Benefits § 162.1802....1) for the NCPDP Data Record in the Detail Data Record. (Incorporated by reference in § 162.920). (2...

45 CFR 162.1802 - Standards for coordination of benefits information transaction.

Code of Federal Regulations, 2013 CFR

2013-10-01

....) (ii) The ASC X12 Standards for Electronic Data Interchange Technical Report Type 3—Health Care Claim... DATA STANDARDS AND RELATED REQUIREMENTS ADMINISTRATIVE REQUIREMENTS Coordination of Benefits § 162.1802....1) for the NCPDP Data Record in the Detail Data Record. (Incorporated by reference in § 162.920). (2...

Cluster of Sound Speed Fields by an Integral Measure

DTIC Science & Technology

2010-06-01

the same cost in time. The increasing the number of sensor depths does not cause execution time to increase. And finally assume that the time required...to be P = Z − ∫ 0 b ∂C(ρ, θ, λ) ∂ρ ∂C(ρ, θ, λ) ∂ρ dρ (2) where (ρ,θ,λ) are the usual geocentric spherical coordinates, and the limits of integration...but using spherical coordinates requires that the horizontal (θ , λ) terms be normalized by the radius. In the case of geocentric coordinates this

Status of research and development in coordinate-measurement technology

NASA Astrophysics Data System (ADS)

Dich, L. Z.; Latyev, S. M.

1994-09-01

This paper discusses problems involved in developing and operating coordinate-measuring machines. The status of this area of precision instrumentation is analyzed. These problems are made critical not only by the requirements of the machine-tool industry but also by those of the microelectronics industry, both of which use coordinate tables, step-up gears, and other equipment in which precise coordinate measurements are necessary.

48 CFR 970.5223-2 - Affirmative procurement program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Contractor shall coordinate its activities with the DOE Recycling Coordinator. Reports required by paragraph (c) of this clause shall be submitted through the DOE Recycling Coordinator. (c) The Contractor shall... “subcontractor” and the term “DOE Recycling Coordinator” will be understood to mean “Contractor Recycling...

The Earth Science Afternoon Constellation: Preparing for Autonomous but Coordinated Operations

NASA Technical Reports Server (NTRS)

Case, Warren; Kelly, Angelita C.; Work, Kevin; Guit, William

2005-01-01

This paper describes how the challenges of coordinating the autonomous operations of geographically dispersed mission control centers for several small and large satellites are being overcome. The Earth Science Afternoon Constellation, also referred to as the "A-Train", is an international grouping of five NASA satellites (two major NASA EOS missions and three NASA/Earth System Science Pathfinder missions) and one French satellite orbiting in close proximity. This grouping of satellites provides scientists with the opportunity to perform coincident observations using data from two or more instruments on various satellites with measurements taken at approximately the same time. Three of the six missions are currently on-orbit, with the two missions expected to join the constellation later this year and one mission in 2007. The operational challenges are daunting for several reasons. There are several Mission Control Centers (widely separated on two continents), operating autonomously under tight budget constraints. All of the Mission Control Centers have reasons to be concerned about safety while flying in close proximity to other satellites, but most Centers did not have the resources or the desire to address this concern alone - the interfaces are too numerous and anticipated operations too costly. Clearly, an efficient approach was needed. This paper describes the steps taken to make this Earth science constellation a reality. Agreements were forged to allow the Mission Control Centers to maintain their autonomy, while ensuring their satellite's safety. Each member mission in the constellation operates independently in accordance with its own mission requirements, but the member missions have agreed to coordinate their operations, i.e., orbital positions and control to ensure the safety of the entire constellation. A centralized system was developed at NASA Goddard Space Flight Center to collect, analyze, and distribute ephemeris data used by each of the mission teams to determine the positions of the satellites in the constellation. The system issues warnings regarding possible dangerous configurations, eliminating the need for redundant capabilities at each Mission Control Center. On-orbit contingency situations were identified and analyzed; agreements were reached in advance of contingency operations to ensure that coordination between the Mission Control Centers can be handled expeditiously and fairly. In this manner, recovery from anomalous situations can be more quickly realized, thereby increasing the science return and reducing costs. The process used to develop these contingency procedures and the systems used to facilitate the contingency resolution are described as well.

Cooperative efforts by industry and government to develop geothermal resources

NASA Technical Reports Server (NTRS)

Butler, D. R.

1974-01-01

The Federal government's current plans for participation in the geothermal field appear to affect four major areas of interest: (1) resources exploration and assessment, (2) resources utilization projects, (3) advanced research and technology, and (4) environmental, legal, and institutional research. Private industry is also actively involved in these same areas of interest. Because of lack of coordination and communication between the private and public sector, it appears that there will be considerable duplication of effort, and, in some cases, serious conflict. It is also likely that this lack of coordination and communication may result in lack of effort in some key areas. Close coordination and communication between government and industry may resolve some of the major problems that are clearly evident.

Chitosan-Copper (II) complex as antibacterial agent: synthesis, characterization and coordinating bond- activity correlation study

NASA Astrophysics Data System (ADS)

Mekahlia, S.; Bouzid, B.

2009-11-01

The antimicrobial activity of chitosan is unstable and sensitive to many factors such as molecular weight. Recent investigations showed that low molecular weight chitosan exhibited strong bactericidal activities compared to chitosan with high molecular weight. Since chitosan degradation can be caused by the coordinating bond, we attempt to synthesize and characterize the chitosan-Cu (II) complex, and thereafter study the coordinating bond effect on its antibacterial activity against Salmonella enteritidis. Seven chitosan-copper complexes with different copper contents were prepared and characterized by FT-IR, UV-vis, XRD and atomic absorption spectrophotometry (AAS). Results indicated that for chitosan-Cu (II) complexes with molar ratio close to 1:1, the inhibition rate reached 100%.

(N-Benzyl-N-isopropyl-dithio-carbamato)chloridodiphenyl-tin(IV).

PubMed

Abdul Muthalib, Amirah Faizah; Baba, Ibrahim; Mohamed Tahir, Mohamed Ibrahim; Ng, Seik Weng; Tiekink, Edward R T

2010-08-11

The Sn(IV) atom in the title organotin dithio-carbamate, [Sn(C(6)H(5))(2)(C(11)H(14)NS(2))Cl], is penta-coordinated by an asymmetrically coordinating dithio-carbamate ligand, a Cl and two ispo-C atoms of the Sn-bound phenyl groups. The resulting C(2)ClS(2) donor set defines a coordination geometry inter-mediate between square-pyramidal and trigonal-bipyramidal with a slight tendency towards the latter. The formation of close intra-molecular C-H⋯Cl and C-H⋯S contacts precludes the Cl and S atoms from forming significant inter-molecular contacts. The presence of C-H⋯π contacts leads to the formation of supra-molecular arrays that stack along the b axis.

The generator coordinate Dirac-Fock method for open-shell atomic systems

NASA Astrophysics Data System (ADS)

Malli, Gulzari L.; Ishikawa, Yasuyuki

1998-11-01

Recently we developed generator coordinate Dirac-Fock and Dirac-Fock-Breit methods for closed-shell systems assuming finite nucleus and have reported Dirac-Fock and Dirac-Fock-Breit energies for the atoms He through Nobelium (Z=102) [see Refs. Reference 10Reference 11Reference 12Reference 13]. In this paper, we generalize our earlier work on closed-shell systems and develop a generator coordinate Dirac-Fock method for open-shell systems. We present results for a number of representative open-shell heavy atoms (with nuclear charge Z>80) including the actinide and superheavy transactinide (with Z>103) atomic systems: Fr (Z=87), Ac (Z=89), and Lr (Z=103) to E113 (eka-thallium, Z=113). The high accuracy obtained in our open-shell Dirac-Fock calculations is similar to that of our closed-shell calculations, and we attribute it to the fact that the representation of the relativistic dynamics of an electron in a spherical ball finite nucleus near the origin in terms of our universal Gaussian basis set is as accurate as that provided by the numerical finite difference method. The DF SCF energies calculated by Desclaux [At. Data. Nucl. Data Tables 12, 311 (1973)] (apart from a typographic error for Fr pointed out here) are higher than those reported here for atoms of some of the superheavy transactinide elements by as much as 5 hartrees (136 eV). We believe that this is due to the use by Desclaux of much larger atomic masses than the currently accepted values for these elements.

Management of sexually transmitted infections in New York State health care organizations: who is thinking about the quality of STI care?

PubMed

Janowski, John Patrick B; Garrett, William S; Feller, Daniel J; Hathaway, Rebecca; Kushner, John; Pelish, Matthew; Agins, Bruce D

2014-09-01

Rising rates of sexually transmitted infections (STIs) warrant a renewed focus on the management of STIs in health care organizations. The extent to which hospitals and community health centers (CHCs) have established processes and allocated staff for the management of STIs within their organizations remains poorly understood. A New York State Department of Health survey was distributed electronically through a closed state communication network to targeted administrators at New York State hospitals and CHCs. The survey asked if STI management in their facilities included the following: the ability to measure and report rates of STIs, a process to assess the quality of STI care and treatment outcomes, and a centralized person/unit to coordinate its work throughout the facility. Multivariate analysis was performed to identify whether organizational characteristics were associated with survey findings. Ninety-five percent (243/256) of hospitals and CHCs responded to the survey. Fifty percent of respondents had a person or unit to report rates of STIs; 30% reported an organization-wide process for monitoring the quality of STI care, which, according to the multivariate analysis, was associated with CHCs; only 23% reported having a centralized person or unit for coordinating STI management. Most facilities report STI cases to comply with public health surveillance requirements but do not measure infection rates, assess the quality of STI care, or coordinate its work throughout the facility. The development of this organizational capacity would likely decrease STI rates, improve treatment outcomes, and address local public health goals.

Precise and Fast Computation of the Gravitational Field of a General Finite Body and Its Application to the Gravitational Study of Asteroid Eros

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fukushima, Toshio, E-mail: Toshio.Fukushima@nao.ac.jp

In order to obtain the gravitational field of a general finite body inside its Brillouin sphere, we developed a new method to compute the field accurately. First, the body is assumed to consist of some layers in a certain spherical polar coordinate system and the volume mass density of each layer is expanded as a Maclaurin series of the radial coordinate. Second, the line integral with respect to the radial coordinate is analytically evaluated in a closed form. Third, the resulting surface integrals are numerically integrated by the split quadrature method using the double exponential rule. Finally, the associated gravitationalmore » acceleration vector is obtained by numerically differentiating the numerically integrated potential. Numerical experiments confirmed that the new method is capable of computing the gravitational field independently of the location of the evaluation point, namely whether inside, on the surface of, or outside the body. It can also provide sufficiently precise field values, say of 14–15 digits for the potential and of 9–10 digits for the acceleration. Furthermore, its computational efficiency is better than that of the polyhedron approximation. This is because the computational error of the new method decreases much faster than that of the polyhedron models when the number of required transcendental function calls increases. As an application, we obtained the gravitational field of 433 Eros from its shape model expressed as the 24 × 24 spherical harmonic expansion by assuming homogeneity of the object.« less

Cell-cell and cell-extracellular matrix adhesions cooperate to organize actomyosin networks and maintain force transmission during dorsal closure.

PubMed

Goodwin, Katharine; Lostchuck, Emily E; Cramb, Kaitlyn M L; Zulueta-Coarasa, Teresa; Fernandez-Gonzalez, Rodrigo; Tanentzapf, Guy

2017-05-15

Tissue morphogenesis relies on the coordinated action of actin networks, cell-cell adhesions, and cell-extracellular matrix (ECM) adhesions. Such coordination can be achieved through cross-talk between cell-cell and cell-ECM adhesions. Drosophila dorsal closure (DC), a morphogenetic process in which an extraembryonic tissue called the amnioserosa contracts and ingresses to close a discontinuity in the dorsal epidermis of the embryo, requires both cell-cell and cell-ECM adhesions. However, whether the functions of these two types of adhesions are coordinated during DC is not known. Here we analyzed possible interdependence between cell-cell and cell-ECM adhesions during DC and its effect on the actomyosin network. We find that loss of cell-ECM adhesion results in aberrant distributions of cadherin-mediated adhesions and actin networks in the amnioserosa and subsequent disruption of myosin recruitment and dynamics. Moreover, loss of cell-cell adhesion caused up-regulation of cell-ECM adhesion, leading to reduced cell deformation and force transmission across amnioserosa cells. Our results show how interdependence between cell-cell and cell-ECM adhesions is important in regulating cell behaviors, force generation, and force transmission critical for tissue morphogenesis. © 2017 Goodwin, Lostchuck, et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

Local Working Agreements and the Tennessee SOPs

EPA Pesticide Factsheets

TN Interagency workgroup convened to improve communication and Coordination, identify permit requirements, implement concurrent reviews, reduce permit revisions; and develop coordinated JD/Pre-App process

GUIDANCE FOR EVALUATING LANDFILL GAS EMISSIONS FROM CLOSED OR ABANDONED FACILITIES

EPA Science Inventory

This document provides guidance to Superfund remedial project managers, on scene coordinators, facility owners, and potentially responsible parties for conducting an air pathway analysis for landfill gas (LFG) emissions under the Comprehensive Environmental Response, Compensation...

Adverse outcome pathways

EPA Science Inventory

The Systems Toxicology Unit of the European Commission Joint Research Centre (JRC) is strongly committed to development and uptake of AOPs. In coordination with the OECD, the JRC and EPA have collaborated closely in the development of training and outreach materials related to th...

33 CFR 100.720 - Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL.

Code of Federal Regulations, 2011 CFR

2011-07-01

... of the racecourse. All coordinates referenced use datum: NAD 83. (4) Big Sarasota Pass will be closed... datum: NAD 1983. (b) Special local regulations. (1) No anchoring will be permitted seaward of the...

33 CFR 100.720 - Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL.

Code of Federal Regulations, 2010 CFR

2010-07-01

... datum: NAD 1983. (b) Special local regulations. (1) No anchoring will be permitted seaward of the... of the racecourse. All coordinates referenced use datum: NAD 83. (4) Big Sarasota Pass will be closed...

33 CFR 100.720 - Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL.

Code of Federal Regulations, 2013 CFR

2013-07-01

... of the racecourse. All coordinates referenced use datum: NAD 83. (4) Big Sarasota Pass will be closed... datum: NAD 1983. (b) Special local regulations. (1) No anchoring will be permitted seaward of the...

33 CFR 100.720 - Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL.

Code of Federal Regulations, 2012 CFR

2012-07-01

... of the racecourse. All coordinates referenced use datum: NAD 83. (4) Big Sarasota Pass will be closed... datum: NAD 1983. (b) Special local regulations. (1) No anchoring will be permitted seaward of the...

33 CFR 100.720 - Annual Suncoast Offshore Grand Prix; Gulf of Mexico, Sarasota, FL.

Code of Federal Regulations, 2014 CFR

2014-07-01

... of the racecourse. All coordinates referenced use datum: NAD 83. (4) Big Sarasota Pass will be closed... datum: NAD 1983. (b) Special local regulations. (1) No anchoring will be permitted seaward of the...

ACHP | Handbook on Coordinating NEPA and Section 106

Science.gov Websites

Search skip specific nav links Home arrow Handbook on Coordinating NEPA and Section 106 Handbook on handbook designed to help coordinate required review processes under the National Historic Preservation Act and the National Environmental Policy Act. The handbook stands to significantly improve the

21 CFR 1311.20 - Coordinators for CSOS digital certificate holders.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Coordinators for CSOS digital certificate holders... REQUIREMENTS FOR ELECTRONIC ORDERS AND PRESCRIPTIONS (Eff. 6-1-10) Obtaining and Using Digital Certificates for Electronic Orders § 1311.20 Coordinators for CSOS digital certificate holders. (a) Each registrant...

77 FR 70526 - Shipping Coordinating Committee; Notice of Committee Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-26

... DEPARTMENT OF STATE [Public Notice 8093] Shipping Coordinating Committee; Notice of Committee Meeting The Shipping Coordinating Committee (SHC) will conduct an open meeting at 10 a.m. on Tuesday... amendments to the requirements for foam-type fire extinguishers in SOLAS regulation II-2/10.5 --Development...

78 FR 53506 - Proposed Information Collection (Care Coordination Home Telehealth (CCHT) Patient Satisfaction...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-29

... Coordination Home Telehealth (CCHT) Patient Satisfaction Survey, VA Form 10-0481); Activity: Comment Request... required to obtain patient perspective on satisfaction with the CCHT program and messaging devices. DATES.... Titles: Care Coordination Home Telehealth (CCHT) Patient Satisfaction Survey, VA Form 10-0481. OMB...

Coordination for the Improvement of Basic Skills.

ERIC Educational Resources Information Center

Roberts, Jane M. E.

The Title II Basic Skills legislation, which is part of the Educational Amendments of 1978, requires coordination of basic skills improvement among related federally-supported programs. Coordination, while essential, is made difficult by the proliferation of agencies and bureaus concerned with basic skills and by the need for autonomy among…

Static Analysis of Large-Scale Multibody System Using Joint Coordinates and Spatial Algebra Operator

PubMed Central

Omar, Mohamed A.

2014-01-01

Initial transient oscillations inhibited in the dynamic simulations responses of multibody systems can lead to inaccurate results, unrealistic load prediction, or simulation failure. These transients could result from incompatible initial conditions, initial constraints violation, and inadequate kinematic assembly. Performing static equilibrium analysis before the dynamic simulation can eliminate these transients and lead to stable simulation. Most exiting multibody formulations determine the static equilibrium position by minimizing the system potential energy. This paper presents a new general purpose approach for solving the static equilibrium in large-scale articulated multibody. The proposed approach introduces an energy drainage mechanism based on Baumgarte constraint stabilization approach to determine the static equilibrium position. The spatial algebra operator is used to express the kinematic and dynamic equations of the closed-loop multibody system. The proposed multibody system formulation utilizes the joint coordinates and modal elastic coordinates as the system generalized coordinates. The recursive nonlinear equations of motion are formulated using the Cartesian coordinates and the joint coordinates to form an augmented set of differential algebraic equations. Then system connectivity matrix is derived from the system topological relations and used to project the Cartesian quantities into the joint subspace leading to minimum set of differential equations. PMID:25045732

Static analysis of large-scale multibody system using joint coordinates and spatial algebra operator.

PubMed

Omar, Mohamed A

2014-01-01

Initial transient oscillations inhibited in the dynamic simulations responses of multibody systems can lead to inaccurate results, unrealistic load prediction, or simulation failure. These transients could result from incompatible initial conditions, initial constraints violation, and inadequate kinematic assembly. Performing static equilibrium analysis before the dynamic simulation can eliminate these transients and lead to stable simulation. Most exiting multibody formulations determine the static equilibrium position by minimizing the system potential energy. This paper presents a new general purpose approach for solving the static equilibrium in large-scale articulated multibody. The proposed approach introduces an energy drainage mechanism based on Baumgarte constraint stabilization approach to determine the static equilibrium position. The spatial algebra operator is used to express the kinematic and dynamic equations of the closed-loop multibody system. The proposed multibody system formulation utilizes the joint coordinates and modal elastic coordinates as the system generalized coordinates. The recursive nonlinear equations of motion are formulated using the Cartesian coordinates and the joint coordinates to form an augmented set of differential algebraic equations. Then system connectivity matrix is derived from the system topological relations and used to project the Cartesian quantities into the joint subspace leading to minimum set of differential equations.

24 CFR 291.306 - Closing requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Closing requirements. 291.306...-Held Single Family Mortgage Loans § 291.306 Closing requirements. (a) Closing date payment. On the closing date, the purchaser must pay to HUD the closing date payment, consisting of the balance of the...

Factors Influencing the Decision to Proceed to Firmware Upgrades to Implanted Pacemakers for Cybersecurity Risk Mitigation.

PubMed

Saxon, Leslie A; Varma, Niraj; Epstein, Laurence M; Ganz, Leonard I; Epstein, Andrew E

2018-05-10

In August 2017, the first major recall for cybersecurity vulnerabilities in pacemakers capable of remote connectivity was released that impacted 465,000 United States patients. 1,2 The FDA approved a firmware update designed by the manufacturer of the devices as a remediation (Abbott , formally St. Jude Medical). The recall was in response to the public disclosure of vulnerability by an investment firm and produced in a lab environment that could allow an unauthorized party in close proximity to a patient to impact the performance of the device or modify device settings via radio frequency communication. 3 While an exploit has not occurred in a patient and requires a high degree of resources and skill to execute, if accomplished, it could pose a significant risk to device safety and essential performance and cause patient harm. The FDA defines this as an uncontrolled vulnerability. 2 The recall recommendations were coordinated between the FDA, the Industrial Control Systems Cyber Emergency Response Team (ICS-CERT), a division of Homeland Security that responds to and coordinates disclosure of critical infrastructure cybersecurity vulnerabilities and Abbott. 1 All parties urged caution and shared decision making between patient and clinician as to whether to have the device firmware update, a process that requires a clinic visit to implement with a device programmer. The manufacturer bench tested the firmware update but the only prior experience with an implanted device firmware updates was a 2012 ICD firmware update that demonstrated a 0.197% risk of device back-up mode pacing after the upgrade was performed.

Data policy and availability supporting global change research, development, and decision-making: An information perspective

NASA Technical Reports Server (NTRS)

Carroll, Bonnie C.; Jack, Robert F.; Cotter, Gladys A.

1990-01-01

An explosion of information has created a crisis for today's information age. It has to be determined how to use the best available information sources, tools, and technology. To do this it is necessary to have leadership at the interagency level to promote a coherent information policy. It is also important to find ways to educate the users of information regarding the tools available to them. Advances in technology resulted in efforts to shift from Disciplinary and Mission-oriented Systems to Decision Support Systems and Personalized Information Systems. One such effort is being made by the Interagency Working Group on Data Management for Global Change (IAWGDMGC). Five federal agencies - the Department of Commerce (DOC), Department of Energy (DOE), National Aeronautics and Space Administration (NASA), National Library of Medicine (NLM), and Department of Defense (DOD) - have an on-going cooperative information management group, CENDI (Commerce, Energy, NASA, NLM, and Defense Information), that is meeting the challenge of coordinating and integrating their information management systems. Although it is beginning to be technically feasible to have a system with text, bibliographic, and numeric data online for the user to manipulate at the user's own workstation, it will require national recognition that the resource investment in such a system is worthwhile, in order to promote its full development. It also requires close cooperation between the producers and users of the information - that is, the research and policy community, and the information community. National resources need to be mobilized in a coordinated manner to move people into the next generation of information support systems.

Closing the information gap: informing better medical decisionmaking through the use of post-market safety and comparative effectiveness information.

PubMed

Fox, Bethany

2012-01-01

While FDA gathers vast amounts of data about prescription drugs prior to their marketing approval, important information about the relative effectiveness and long term safety of products is not required for approval, and often is never collected. Increased postmarket research on the safety and comparative effectiveness of products would improve medical decisionmaking and lead to better clinical outcomes. Fortunately, Congress has recognized the value of this information for healthcare professionals. In response to a congressional mandate in the FDA Amendments Act (FDAAA), FDA is developing the Sentinel Initiative, an active surveillance system for monitoring postmarket drug safety issues. FDAAA also authorized FDA to require a drug sponsor to conduct postmarket safety studies or clinical trials to address a specific safety concern. To increase the repository of comparative effectiveness information, Congress established the Patient-Centered Outcomes Research Institute (PCORI) in the Patient Protection and Affordable Care Act (PPACA), directing it to manage comparative effectiveness research (CER). This article discusses the need for better safety and comparative effectiveness information and outlines methods to efficiently conduct the research and communicate it effectively to healthcare professionals. Coordination between FDA and the PCORI in gathering and communicating postmarket information is recommended. Medical source data collected by the Sentinel Initiative should be used for CER in addition to postmarket safety surveillance, and FDA and the PCORI should adopt identical standards for the distribution and communication of CER. Coordination between the two entities is recommended to save costs, reduce duplication of efforts, and to generate and communicate more information on prescription drugs for medical decisionmakers.

Online Optimal Control of Connected Vehicles for Efficient Traffic Flow at Merging Roads

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rios-Torres, Jackeline; Malikopoulos, Andreas; Pisu, Pierluigi

2015-01-01

This paper addresses the problem of coordinating online connected vehicles at merging roads to achieve a smooth traffic flow without stop-and-go driving. We present a framework and a closed-form solution that optimize the acceleration profile of each vehicle in terms of fuel economy while avoiding collision with other vehicles at the merging zone. The proposed solution is validated through simulation and it is shown that coordination of connected vehicles can reduce significantly fuel consumption and travel time at merging roads.

Modal Filtering for Control of Flexible Aircraft

NASA Technical Reports Server (NTRS)

Suh, Peter M.; Mavris, Dimitri N.

2013-01-01

Modal regulators and deformation trackers are designed for an open-loop fluttering wing model. The regulators are designed with modal coordinate and accelerometer inputs respectively. The modal coordinates are estimated with simulated fiber optics. The robust stability of the closed-loop systems is compared in a structured singular-value vector analysis. Performance is evaluated and compared in a gust alleviation and flutter suppression simulation. For the same wing and flight condition two wing-shape-tracking control architectures are presented, which achieve deformation control at any point on the wing.

An Analysis of the Accessibility of Earth-Approaching Asteroids.

DTIC Science & Technology

1985-12-01

coordinate system. Outputs are the X,Y,Z coordinates of the sun in the geocentric-equatorial coordinate system. The obliquity of the ecliptic is a variable...All positions and velocities are calculated in heliocentric- ecliptic coordinates thus requiring no transformations into unusual frames of reference...tion vectors of the departure and arrival planets in the heliocentric- ecliptic reference frame. ,\\. , V I(W() - / n (16) %: ~22% .b The angle between

Sensitivity and specificity of a new MRI method evaluating temporo-mandibular joint disc-condyle relationships: an in vivo study.

PubMed

Benbelaïd, R; Fleiter, B

2006-03-01

The aim of this study was to evaluate sensitivity and specificity of a new method to locate temporo-mandibular joint (TMJ) disc using magnetic resonance imaging (MRI) and analyze disc-condyle relationships, in asymptomatic subjects and patients with disc displacement. Twenty-nine sagittal MRI of 16 subjects, 8 asymptomatic volunteers and 8 subjects with anterior disc displacement, were carried out during controlled opening from intercuspal position up to a 25 mm opening. Selected sections were analyzed with a graphic computerized system of coordinates. The total surface area (TS) of disc section was separated into anterior surface area (AS) and posterior surface area. Areas were determined by computer. Two trained examiners drew images at random. The reliability of AS/TS ratio index was evaluated in a previous study. AS/TS ratio sensitivity (Se) and specificity (Sp) were calculated closed mouth, 5 mm open and 25 mm open mouth. Best sensitivity (Se=0.63) and specificity (Sp=0.81) were obtained when MRI was realized with closed mouth and 25 mm open mouth. Lower sensitivity was observed when MRI was performed either with closed mouth (Se=0.54) or 25 mm open mouth (Se=0.18). Lower specificity was observed with 5 mm open mouth (Sp=0.68). In conclusion, it was confirmed as well that MRI of anterior disc displacement should be performed with closed mouth and opened mouth. Thus, further studies are required to assess disc displacement and mechanical alterations and to evaluate the risk of direct damage on TMJ tissues.

34 CFR 364.29 - What are the requirements for coordinating Federal and State sources of funding?

Code of Federal Regulations, 2011 CFR

2011-07-01

... EDUCATION STATE INDEPENDENT LIVING SERVICES PROGRAM AND CENTERS FOR INDEPENDENT LIVING PROGRAM: GENERAL... 34 Education 2 2011-07-01 2010-07-01 true What are the requirements for coordinating Federal and State sources of funding? 364.29 Section 364.29 Education Regulations of the Offices of the Department...

34 CFR 364.29 - What are the requirements for coordinating Federal and State sources of funding?

Code of Federal Regulations, 2010 CFR

2010-07-01

... EDUCATION STATE INDEPENDENT LIVING SERVICES PROGRAM AND CENTERS FOR INDEPENDENT LIVING PROGRAM: GENERAL... 34 Education 2 2010-07-01 2010-07-01 false What are the requirements for coordinating Federal and State sources of funding? 364.29 Section 364.29 Education Regulations of the Offices of the Department...

34 CFR 403.15 - What are the personnel requirements regarding coordination with services under chapter 1 of title...

Code of Federal Regulations, 2010 CFR

2010-07-01

... VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION STATE VOCATIONAL AND APPLIED TECHNOLOGY EDUCATION... 34 Education 3 2010-07-01 2010-07-01 false What are the personnel requirements regarding coordination with services under chapter 1 of title I of the Elementary and Secondary Education Act? 403.15...

Raising the Bar: Challenging Students in a Capstone Project Course with an Android and Mobile Web Parallel Development Team Project

ERIC Educational Resources Information Center

Wong, Wilson; Pepe, James; Englander, Irv

2017-01-01

Information systems capstone projects aim to prepare students for what they will encounter in the industry after graduation. Corporate application development is often a complex endeavor that requires coordination between related products. For example, software development in the mobile application sector may require a coordinated parallel…

Stakeholder perceptions of aid coordination implementation in the Zambian health sector.

PubMed

Sundewall, Jesper; Jönsson, Kristina; Cheelo, Caesar; Tomson, Göran

2010-05-01

In this study, we analysed stakeholder perceptions of the process of implementing the coordination of health-sector aid in Zambia, Africa. The aim of coordination of health aid is to increase the effectiveness of health systems and to ensure that donors comply with national priorities. With increases in the number of donors involved and resources available for health aid globally, the attention devoted to coordination worldwide has risen. While the theoretical basis of coordination has been relatively well-explored, less research has been carried out on the practicalities of how such coordination is to be implemented. In our study, we focused on potential differences between the views of the stakeholders, both government and donors, on the systems by which health aid is coordinated. A qualitative case study was conducted comprising interviews with government and donor stakeholders in the health sector, as well as document review and observations of meetings. Results suggested that stakeholders are generally satisfied with the implementation of health-sector aid coordination in Zambia. However, there were differences in perceptions of the level of coordination of plans and agreements, which can be attributed to difficulties in harmonizing and aligning organizational requirements with the Zambian health-sector plans. In order to achieve the aims of the Paris Declaration; to increase harmonization, alignment and ownership--resources from donors must be better coordinated in the health sector planning process. This requires careful consideration of contextual constraints surrounding each donor. Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.

Interventions for coordination of walking following stroke: systematic review.

PubMed

Hollands, Kristen L; Pelton, Trudy A; Tyson, Sarah F; Hollands, Mark A; van Vliet, Paulette M

2012-03-01

Impairments in gait coordination may be a factor in falls and mobility limitations after stroke. Therefore, rehabilitation targeting gait coordination may be an effective way to improve walking post-stroke. This review sought to examine current treatments that target impairments of gait coordination, the theoretical basis on which they are derived and the effects of such interventions. Few high quality RCTs with a low risk of bias specifically targeting and measuring restoration of coordinated gait were found. Consequently, we took a pragmatic approach to describing and quantifying the available evidence and included non-randomised study designs and limited the influence of heterogeneity in experimental design and control comparators by restricting meta-analyses to pre- and post-test comparisons of experimental interventions only. Results show that physiotherapy interventions significantly improved gait function and coordination. Interventions involving repetitive task-specific practice and/or auditory cueing appeared to be the most promising approaches to restore gait coordination. The fact that overall improvements in gait coordination coincided with increased walking speed lends support to the hypothesis that targeting gait coordination gait may be a way of improving overall walking ability post-stroke. However, establishing the mechanism for improved locomotor control requires a better understanding of the nature of both neuroplasticity and coordination deficits in functional tasks after stroke. Future research requires the measurement of impairment, activity and cortical activation in an effort to establish the mechanism by which functional gains are achieved. Copyright © 2011 Elsevier B.V. All rights reserved.

A framework for bridging the gap in the care of familial hypercholesterolaemia in the community: pragmatic and economic perspectives.

PubMed

Purchase, Sharon; Vickery, Alistair; Garton-Smith, Jacquie; O'Leary, Peter; Sullivan, David; Slattery, Mark; Playford, David; Watts, Gerald

2014-12-01

To analyze various business models for improving the diagnosis and treatment of familial hypercholesterolaemia. Five different strategies were analyzed and data were collected through documentary analysis and structured interviews. Interviewees included professionals from universities, Western Australia Department of Health, private medical practitioners and not-for-profit organizations. Two business models are recommended: alliance with general practitioners and primary health care organizations and a joint venture model between private cardiology clinics and lipid disorder clinics in the public sector. Primary care providers are in a good position to co-ordinate across the multi-disciplinary health services required to treat familial hypercholesterolaemia within the population. Devolution of knowledge on treatment of familial hypercholesterolaemia from centralized specialist hospital clinics to primary care services is required to improve the rate of detection of this condition in the community. An International Classification of Disease (ICD)-10 and/or a Diagnosis-Related Group (DRG) code is required to codify, catalogue and document new cases and treatment, as well as to facilitate research and re-imbursement strategies. Primary Health Care Organizations can usefully facilitate the transfer of knowledge on best standard of care to general practice, but the best model of care will require close integration of care with specialist and academic centres.

His86 from the N-terminus of frataxin coordinates iron and is required for Fe-S cluster synthesis.

PubMed

Gentry, Leslie E; Thacker, Matthew A; Doughty, Reece; Timkovich, Russell; Busenlehner, Laura S

2013-09-03

Human frataxin has a vital role in the biosynthesis of iron-sulfur (Fe-S) clusters in mitochondria, and its deficiency causes the neurodegenerative disease Friedreich's ataxia. Proposed functions for frataxin in the Fe-S pathway include iron donation to the Fe-S cluster machinery and regulation of cysteine desulfurase activity to control the rate of Fe-S production, although further molecular detail is required to distinguish these two possibilities. It is well established that frataxin can coordinate iron using glutamate and aspartate side chains on the protein surface; however, in this work we identify a new iron coordinating residue in the N-terminus of human frataxin using complementary spectroscopic and structural approaches. Further, we demonstrate that His86 in this N-terminal region is required for high affinity iron coordination and iron assembly of Fe-S clusters by ISCU as part of the Fe-S cluster biosynthetic complex. If a binding site that includes His86 is important for Fe-S cluster synthesis as part of its chaperone function, this raises the possibility that either iron binding at the acidic surface of frataxin may be spurious or that it is required for protein-protein interactions with the Fe-S biosynthetic quaternary complex. Our data suggest that iron coordination to frataxin may be significant to the Fe-S cluster biosynthesis pathway in mitochondria.

Structure, Bonding, and Stability of Mercury Complexes with Thiolate and Thioether Ligands from High-Resolution XANES Spectroscopy and First-Principles Calculations.

PubMed

Manceau, Alain; Lemouchi, Cyprien; Rovezzi, Mauro; Lanson, Martine; Glatzel, Pieter; Nagy, Kathryn L; Gautier-Luneau, Isabelle; Joly, Yves; Enescu, Mironel

2015-12-21

We present results obtained from high energy-resolution L3-edge XANES spectroscopy and first-principles calculations for the structure, bonding, and stability of mercury(II) complexes with thiolate and thioether ligands in crystalline compounds, aqueous solution, and macromolecular natural organic matter (NOM). Core-to-valence XANES features that vary in intensity differentiate with unprecedented sensitivity the number and identity of Hg ligands and the geometry of the ligand environment. Post-Hartree-Fock XANES calculations, coupled with natural population analysis, performed on MP2-optimized Hg[(SR)2···(RSR)n] complexes show that the shape, position, and number of electronic transitions observed at high energy-resolution are directly correlated to the Hg and S (l,m)-projected empty densities of states and occupations of the hybridized Hg 6s and 5d valence orbitals. Linear two-coordination, the most common coordination geometry in mercury chemistry, yields a sharp 2p to 6s + 5d electronic transition. This transition varies in intensity for Hg bonded to thiol groups in macromolecular NOM. The intensity variation is explained by contributions from next-nearest, low-charge, thioether-type RSR ligands at 3.0-3.3 Å from Hg. Thus, Hg in NOM has two strong bonds to thiol S and k additional weak Hg···S contacts, or 2 + k coordination. The calculated stabilization energy is -5 kcal/mol per RSR ligand. Detection of distant ligands beyond the first coordination shell requires precise measurement of, and comparison to, spectra of reference compounds as well as accurate calculation of spectra for representative molecular models. The combined experimental and theoretical approaches described here for Hg can be applied to other closed-shell atoms, such as Ag(I) and Au(I). To facilitate further calculation of XANES spectra, experimental data, a new crystallographic structure of a key mercury thioether complex, Cartesian coordinates of the computed models, and examples of input files are provided as Supporting Information .

Environmental Compliance Issue Coordination

EPA Pesticide Factsheets

An order to establish the Department of Energy (DOE) requirements for coordination of significant environmental compliance issues to ensure timely development and consistent application of Departmental environmental policy and guidance

Tension (re)builds: Biophysical mechanisms of embryonic wound repair.

PubMed

Zulueta-Coarasa, Teresa; Fernandez-Gonzalez, Rodrigo

2017-04-01

Embryonic tissues display an outstanding ability to rapidly repair wounds. Epithelia, in particular, serve as protective layers that line internal organs and form the skin. Thus, maintenance of epithelial integrity is of utmost importance for animal survival, particularly at embryonic stages, when an immune system has not yet fully developed. Rapid embryonic repair of epithelial tissues is conserved across species, and involves the collective migration of the cells around the wound. The migratory cell behaviours associated with wound repair require the generation and transmission of mechanical forces, not only for the cells to move, but also to coordinate their movements. Here, we review the forces involved in embryonic wound repair. We discuss how different force-generating structures are assembled at the molecular level, and the mechanisms that maintain the balance between force-generating structures as wounds close. Finally, we describe the mechanisms that cells use to coordinate the generation of mechanical forces around the wound. Collective cell movements and their misregulation have been associated with defective tissue repair, developmental abnormalities and cancer metastasis. Thus, we propose that understanding the role of mechanical forces during embryonic wound closure will be crucial to develop therapeutic interventions that promote or prevent collective cell movements under pathological conditions. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

SURMODERR: A MATLAB toolbox for estimation of velocity uncertainties of a non-permanent GPS station

NASA Astrophysics Data System (ADS)

Teza, Giordano; Pesci, Arianna; Casula, Giuseppe

2010-08-01

SURMODERR is a MATLAB toolbox intended for the estimation of reliable velocity uncertainties of a non-permanent GPS station (NPS), i.e. a GPS receiver used in campaign-style measurements. The implemented method is based on the subsampling of daily coordinate time series of one or more continuous GPS stations located inside or close to the area where the NPSs are installed. The continuous time series are subsampled according to real or planned occupation tables and random errors occurring in antenna replacement on different surveys are taken into account. In order to overcome the uncertainty underestimation that typically characterizes short duration GPS time series, statistical analysis of the simulated data is performed to estimate the velocity uncertainties of this real NPS. The basic hypotheses required are: (i) the signal must be a long-term linear trend plus seasonal and colored noise for each coordinate; (ii) the standard data processing should have already been performed to provide daily data series; and (iii) if the method is applied to survey planning, the future behavior should not be significantly different from the past behavior. In order to show the strength of the approach, two case studies with real data are presented and discussed (Central Apennine and Panarea Island, Italy).

Space Weather Modeling Services at the Community Coordinated Modeling Center

NASA Technical Reports Server (NTRS)

Hesse, Michael

2006-01-01

The Community Coordinated Modeling Center (CCMC) is a multi-agency partnership, which aims at the creation of next generation space weather models. The goal of the CCMC is to support the research and developmental work necessary to substantially increase the present-day modeling capability for space weather purposes, and to provide models for transition to the Rapid Prototyping Centers at the space weather forecast centers. This goal requires close collaborations with and substantial involvement of the research community. The physical regions to be addressed by CCMC-related activities range from the solar atmosphere to the Earth's upper atmosphere. The CCMC is an integral part of the National Space Weather Program Implementation Plan, of NASA's Living With a Star (LWS) initiative, and of the Department of Defense Space Weather Transition Plan. CCMC includes a facility at NASA Goddard Space Flight Center. CCMC also provides, to the research community, access to state-of-the-art space research models. In this paper we will provide a description of the current CCMC status, discuss current plans, research and development accomplishments and goals, and describe the model testing and validation process undertaken as part of the CCMC mandate. Special emphasis will be on solar and heliospheric models currently residing at CCMC, and on plans for validation and verification.

Study on portable optical 3D coordinate measuring system

NASA Astrophysics Data System (ADS)

Ren, Tongqun; Zhu, Jigui; Guo, Yinbiao

2009-05-01

A portable optical 3D coordinate measuring system based on digital Close Range Photogrammetry (CRP) technology and binocular stereo vision theory is researched. Three ultra-red LED with high stability is set on a hand-hold target to provide measuring feature and establish target coordinate system. Ray intersection based field directional calibrating is done for the intersectant binocular measurement system composed of two cameras by a reference ruler. The hand-hold target controlled by Bluetooth wireless communication is free moved to implement contact measurement. The position of ceramic contact ball is pre-calibrated accurately. The coordinates of target feature points are obtained by binocular stereo vision model from the stereo images pair taken by cameras. Combining radius compensation for contact ball and residual error correction, object point can be resolved by transfer of axes using target coordinate system as intermediary. This system is suitable for on-field large-scale measurement because of its excellent portability, high precision, wide measuring volume, great adaptability and satisfying automatization. It is tested that the measuring precision is near to +/-0.1mm/m.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cosgrove, F.R.

The once taboo subject of blasting near buried Natural Gas Pipelines has taken a different turn at one New England Gas Utility Company. Blasting to remove trench rock in close proximity to their facilities is rapidly becoming their most recommended method of choice as far as they are concerned. This method has become their method of choice because many projects were successfully completed due in part to a revised policy regarding blasting near their facilities that was implemented last year. The objective of this policy is to work cooperatively with the Blaster. By doing this, two very important and easilymore » obtainable goals were established of which the first goal is to crete A Very Satisfied Customer -- The Blaster. By accomplishing this goal, a natural transition was made into their second goal which is to achieve a successful completion to the project at hand while maintaining a high level of safety. Both of these goals are met through a combined effort to treat each project as a separate project which has unique characteristics that are site specific and which require the three most important elements in all projects. These three elements are: Close Coordination, Cooperation and Communication by both the Blaster and The Gas Company.« less

Space and time in the quantum universe.

NASA Astrophysics Data System (ADS)

Smolin, L.

This paper is devoted to the problem of constructing a quantum theory that could describe a closed system - a quantum cosmology. The author argues that this problem is an aspect of a much older problem - that of how to eliminate from the physical theories "ideal elements", which are elements of the mathematical structure whose interpretation requires the existence of things outside the dynamical system described by the theory. This discussion is aimed at uncovering criteria that a theory of quantum cosmology must satisfy, if it is to give physically sensible predictions. The author proposes three such criteria and shows that conventional quantum cosmology can only satisfy them, if there is an intrinsic time coordinate on the phase space of the theory. It is shown that approaches based on correlations in the wave function, that do not use an inner product, cannot satisfy these criteria. As example, the author discusses the problem of quantizing a class of relational dynamical models invented by Barbour and Bertotti. The dynamical structure of these theories is closely analogous to general relativity, and the problem of their measurement theory is also similar. It is concluded that these theories can only be sensibly quantized if they contain an intrinsic time.

Extending Validated Human Performance Models to Explore NextGen Concepts

NASA Technical Reports Server (NTRS)

Gore, Brian Francis; Hooey, Becky Lee; Mahlstedt, Eric; Foyle, David C.

2012-01-01

To meet the expected increases in air traffic demands, NASA and FAA are researching and developing Next Generation Air Transportation System (NextGen) concepts. NextGen will require substantial increases in the data available to pilots on the flight deck (e.g., weather,wake, traffic trajectory predictions, etc.) to support more precise and closely coordinated operations (e.g., self-separation, RNAV/RNP, and closely spaced parallel operations, CSPOs). These NextGen procedures and operations, along with the pilot's roles and responsibilities, must be designed with consideration of the pilot's capabilities and limitations. Failure to do so will leave the pilots, and thus the entire aviation system, vulnerable to error. A validated Man-machine Integration and design Analysis System (MIDAS) v5 model was extended to evaluate anticipated changes to flight deck and controller roles and responsibilities in NextGen approach and Land operations. Compared to conditions when the controllers are responsible for separation on decent to land phase of flight, the output from these model predictions suggest that the flight deck response time to detect the lead aircraft blunder will decrease, pilot scans to the navigation display will increase, and workload will increase.

75 FR 43917 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-27

...: International Trade Administration. Title: U.S. Government Trade Event Information Request. OMB Control Number... priority essential to improving U.S. trade performance. The International Trade Administration's (ITA... procurements worldwide. The Advocacy Center works closely with the Trade Promotion Coordination Committee...

Topographic Information Requirements and Computer-Graphic Display Techniques for Nap-of-the-Earth Flight.

DTIC Science & Technology

1979-12-01

required of the Army aviator. The successful accomplishment of many of these activities depends upon the aviator’s ability to extract information from maps...Cruise NOE VBI Determine Position VB2 Crew Coordination (Topographic) VB3 Radio Communication VI . TERM4INATION C. Post-Flight VIC1 Debriefing 11LA 1I...NOE FUNCTION: VBI DETERMINE POSITION INFORMATION REQUIREMENT SPECIFICS SOURCE COMMENTS See Function IIIAl ! FUNCTION: VB2 CREW COORDINATION

40 CFR 233.31 - Coordination requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... discharge may affect the biological, chemical, or physical integrity of the waters of any State(s) other... coordinated with Federal and Federal-State water related planning and review processes. ...

The Role and Load of the Athletic Training Clinical Education Coordinator

ERIC Educational Resources Information Center

Radtke, Sarah

2017-01-01

Context: The position of clinical education coordinator has been identified as a required one in athletic training education. However, the literature has yet to address the job responsibilities of clinical education coordinators and the commensurate work load/release time needed to accomplish these responsibilities in athletic training education.…

The Developmental Effect of Concurrent Cognitive and Locomotor Skills: Time-Sharing from a Dynamical Perspective.

ERIC Educational Resources Information Center

Whitall, Jill

1991-01-01

Presents research on the effects of concurrent verbal cognition on locomotor skills. Results revealed no interference with coordination variables across age, but some interference with control variables, particularly in younger subjects. Coordination of gait required less attention than setting of control parameters. This coordination was in place…

Jaw-Phonatory Coordination in Chronic Developmental Stuttering

ERIC Educational Resources Information Center

Loucks, Torrey M. J.; De Nil, Luc F.; Sasisekaran, Jayanthi

2007-01-01

A deficiency in sensorimotor integration in a person who stutters may be a factor in the pathophysiology of developmental stuttering. To test oral sensorimotor function in adults who stutter, we used a task that requires the coordination of a jaw-opening movement with phonation onset. The task was adapted from previous limb coordination studies,…

Nonlinear finite element formulation for the large displacement analysis in multibody system dynamics

NASA Technical Reports Server (NTRS)

Rismantab-Sany, J.; Chang, B.; Shabana, A. A.

1989-01-01

A total Lagrangian finite element formulation for the deformable bodies in multibody mechanical systems that undergo finite relative rotations is developed. The deformable bodies are discretized using finite element methods. The shape functions that are used to describe the displacement field are required to include the rigid body modes that describe only large translational displacements. This does not impose any limitations on the technique because most commonly used shape functions satisfy this requirement. The configuration of an element is defined using four sets of coordinate systems: Body, Element, Intermediate element, Global. The body coordinate system serves as a unique standard for the assembly of the elements forming the deformable body. The element coordinate system is rigidly attached to the element and therefore it translates and rotates with the element. The intermediate element coordinate system, whose axes are initially parallel to the element axes, has an origin which is rigidly attached to the origin of the body coordinate system and is used to conveniently describe the configuration of the element in undeformed state with respect to the body coordinate system.

Implementation of system dynamic simulation method to optimize profit in supply chain network of vegetable product

NASA Astrophysics Data System (ADS)

Tama, I. P.; Akbar, Z.; Eunike, A.

2018-04-01

Vegetables are categorized as a perishable product, which is a product with short lifespan thus requires proper handling and planning to reduce losses caused by the short lifespan. In order to reduce the losses, coordination among the players in the supply chain is required. On the other hand, the decision in the supply chain of vegetables and other farming products in the traditional market of developing country is independent among the players. This research is conducted by using System Dynamic Simulation method to develop model and scenario by coordinating the supply quantity amongst players in the supply chain. The scenarios are developed based on newsboy inventory model. This study aims to compare scenarios combining tiers involved in coordination program. The result shows that coordination in supply chain increases total supply chain profit, although there will always be players who experienced decrements in profit. The scenario of coordination among the farmer, the distributor, and the wholesaler resulted in the highest increase in total supply chain profit compared to other coordination scenarios, with an increased value of 10.49%.

Roles and relationships between health professionals involved in insulin initiation for people with type 2 diabetes in the general practice setting: a qualitative study drawing on relational coordination theory.

PubMed

Manski-Nankervis, Jo-Anne; Furler, John; Blackberry, Irene; Young, Doris; O'Neal, David; Patterson, Elizabeth

2014-01-31

The majority of care for people with type 2 diabetes occurs in general practice, however when insulin initiation is required it often does not occur in this setting or in a timely manner and this may have implications for the development of complications. Increased insulin initiation in general practice is an important goal given the increasing prevalence of type 2 diabetes and a relative shortage of specialists. Coordination between primary and secondary care, and between medical and nursing personnel, may be important in achieving this. Relational coordination theory identifies key concepts that underpin effective interprofessional work: communication which is problem solving, timely, accurate and frequent and relationships between professional roles which are characterized by shared goals, shared knowledge and mutual respect. This study explores roles and relationships between health professionals involved in insulin initiation in order to gain an understanding of factors which may impact on this task being carried out in the general practice setting. 21 general practitioners, practice nurses, diabetes nurse educators and physicians were purposively sampled to participate in a semi-structured interview. Transcripts of the interviews were analysed using framework analysis. There were four closely interlinked themes identified which impacted on how health professionals worked together to initiate people with type 2 diabetes on insulin: 1. Ambiguous roles; 2. Uncertain competency and capacity; 3. Varying relationships and communication; and 4. Developing trust and respect. This study has shown that insulin initiation is generally recognised as acceptable in general practice. The role of the DNE and practice nurse in this space and improved communication and relationships between health professionals across organisations and levels of care are factors which need to be addressed to support this clinical work. Relational coordination provides a useful framework for exploring these issues.

Reference coordinate systems: An update. Supplement 11

NASA Technical Reports Server (NTRS)

Mueller, Ivan I.

1988-01-01

A common requirement for all geodetic investigations is a well-defined coordinate system attached to the earth in some prescribed way, as well as a well-defined inertial coordinate system in which the motions of the terrestrial frame can be monitored. The paper deals with the problems encountered when establishing such coordinate systems and the transformations between them. In addition, problems related to the modeling of the deformable earth are discussed. This paper is an updated version of the earlier work, Reference Coordinate Systems for Earth Dynamics: A Preview, by the author.

Determining coordinates of the rotational pole using satellite data from four sites

NASA Astrophysics Data System (ADS)

Pisacane, V. L.; Dillon, S. C.

1981-02-01

The precision of the terrestrial coordinates of the rotational pole was determined from the satellite data using the Navy Navigation Satellite System (TRANSIT). Observations were made in Maine, Minnesota, California, and Hawaii; the data agreed with extrapolated and final coordinates from the Bureau International de l'Heure and final coordinates from the Doppler Polar Motion Service. The investigation indicates that low-cost and near-real-time estimates of the terrestrial coordinates of the pole are available as a by-product of the routine support required for the TRANSIT.

Patient- and family-centered care coordination: a framework for integrating care for children and youth across multiple systems.

PubMed

2014-05-01

Understanding a care coordination framework, its functions, and its effects on children and families is critical for patients and families themselves, as well as for pediatricians, pediatric medical subspecialists/surgical specialists, and anyone providing services to children and families. Care coordination is an essential element of a transformed American health care delivery system that emphasizes optimal quality and cost outcomes, addresses family-centered care, and calls for partnership across various settings and communities. High-quality, cost-effective health care requires that the delivery system include elements for the provision of services supporting the coordination of care across settings and professionals. This requirement of supporting coordination of care is generally true for health systems providing care for all children and youth but especially for those with special health care needs. At the foundation of an efficient and effective system of care delivery is the patient-/family-centered medical home. From its inception, the medical home has had care coordination as a core element. In general, optimal outcomes for children and youth, especially those with special health care needs, require interfacing among multiple care systems and individuals, including the following: medical, social, and behavioral professionals; the educational system; payers; medical equipment providers; home care agencies; advocacy groups; needed supportive therapies/services; and families. Coordination of care across settings permits an integration of services that is centered on the comprehensive needs of the patient and family, leading to decreased health care costs, reduction in fragmented care, and improvement in the patient/family experience of care. Copyright © 2014 by the American Academy of Pediatrics.

30 CFR 773.5 - Regulatory coordination with requirements under other laws.

Code of Federal Regulations, 2013 CFR

2013-07-01

... operations with applicable requirements of the Endangered Species Act of 1973, as amended (16 U.S.C. 1531 et seq.); the Fish and Wildlife Coordination Act, as amended (16 U.S.C. 661 et seq.); the Migratory Bird Treaty Act of 1918, as amended (16 U.S.C. 703 et seq.); The National Historic Preservation Act of 1966...

30 CFR 773.5 - Regulatory coordination with requirements under other laws.

Code of Federal Regulations, 2011 CFR

2011-07-01

... operations with applicable requirements of the Endangered Species Act of 1973, as amended (16 U.S.C. 1531 et seq.); the Fish and Wildlife Coordination Act, as amended (16 U.S.C. 661 et seq.); the Migratory Bird Treaty Act of 1918, as amended (16 U.S.C. 703 et seq.); The National Historic Preservation Act of 1966...

30 CFR 773.5 - Regulatory coordination with requirements under other laws.

Code of Federal Regulations, 2014 CFR

2014-07-01

... operations with applicable requirements of the Endangered Species Act of 1973, as amended (16 U.S.C. 1531 et seq.); the Fish and Wildlife Coordination Act, as amended (16 U.S.C. 661 et seq.); the Migratory Bird Treaty Act of 1918, as amended (16 U.S.C. 703 et seq.); The National Historic Preservation Act of 1966...

30 CFR 773.5 - Regulatory coordination with requirements under other laws.

Code of Federal Regulations, 2012 CFR

2012-07-01

... operations with applicable requirements of the Endangered Species Act of 1973, as amended (16 U.S.C. 1531 et seq.); the Fish and Wildlife Coordination Act, as amended (16 U.S.C. 661 et seq.); the Migratory Bird Treaty Act of 1918, as amended (16 U.S.C. 703 et seq.); The National Historic Preservation Act of 1966...

30 CFR 773.5 - Regulatory coordination with requirements under other laws.

Code of Federal Regulations, 2010 CFR

2010-07-01

... operations with applicable requirements of the Endangered Species Act of 1973, as amended (16 U.S.C. 1531 et seq.); the Fish and Wildlife Coordination Act, as amended (16 U.S.C. 661 et seq.); the Migratory Bird Treaty Act of 1918, as amended (16 U.S.C. 703 et seq.); The National Historic Preservation Act of 1966...

34 CFR 403.15 - What are the personnel requirements regarding coordination with services under chapter 1 of title...

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 3 2011-07-01 2011-07-01 false What are the personnel requirements regarding coordination with services under chapter 1 of title I of the Elementary and Secondary Education Act? 403.15 Section 403.15 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF...

20 CFR 663.320 - What are the requirements for coordination of WIA training funds and other grant assistance?

Code of Federal Regulations, 2010 CFR

2010-04-01

... coordination of WIA training funds and other grant assistance? (a) WIA funding for training is limited to participants who: (1) Are unable to obtain grant assistance from other sources to pay the costs of their training; or (2) Require assistance beyond that available under grant assistance from other sources to pay...

75 FR 7370 - Closed Captioning of Video Programming; Closed Captioning Requirements for Digital Television...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-19

... 08-255] Closed Captioning of Video Programming; Closed Captioning Requirements for Digital Television... Captioning of Video Programming; Closed Captioning Requirements for Digital Television Receivers, Declaratory... 1594, January 13, 2009, is effective February 19, 2010. Video programming distributors must comply with...

Coordinating a Supply Chain with Price and Advertisement Dependent Stochastic Demand

PubMed Central

Li, Liying; Wang, Yong; Yan, Xiaoming

2013-01-01

This paper investigates pricing and ordering as well as advertising coordination issues in a single-manufacturer single-retailer supply chain, where the manufacturer sells a newsvendor-type product through the retailer who faces a stochastic demand depending on both retail price and advertising expenditure. Under the assumption that the market demand has a multiplicative functional form, the Stackelberg and cooperative game models are developed, and the closed form solution to each model is provided as well. Comparisons and insights are presented. We show that a properly designed revenue-cost-sharing contract can achieve supply chain coordination and lead to a Pareto improving win-win situation for channel members. We also discuss the allocation of the extra joint profit according to individual supply chain members' risk preferences and negotiating powers. PMID:24453832

Velocity-free attitude coordinated tracking control for spacecraft formation flying.

PubMed

Hu, Qinglei; Zhang, Jian; Zhang, Youmin

2018-02-01

This article investigates the velocity-free attitude coordinated tracking control scheme for a group of spacecraft with the assumption that the angular velocities of the formation members are not available in control feedback. Initially, an angular velocity observer is constructed based on each individual's attitude quarternion. Then, the distributed attitude coordinated control law is designed by using the observed states, in which adaptive control method is adopted to handle the external disturbances. Stability of the overall closed-loop system is analyzed theoretically, which shows the system trajectory converges to a small set around origin with fast convergence rate. Numerical simulations are performed to demonstrate fast convergence and improved tracking performance of the proposed control strategy. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

Coordination and structure of Ca(II)-acetate complexes in aqueous solution studied by a combination of Raman and XAFS spectroscopies

NASA Astrophysics Data System (ADS)

Muñoz Noval, Álvaro; Nishio, Daisuke; Kuruma, Takuya; Hayakawa, Shinjiro

2018-06-01

The determination of the structure of Ca(II)-acetate in aqueous solution has been addressed by combining Raman and X-ray absorption fine structure spectroscopies. The pH-dependent speciation of the acetate/Ca(II) system has been studied observing modifications in specific Raman bands of the carboxyl group. The current results evidence the Ca(II)-acetate above acetate pKa forms a bidentate complex and presents a coordination 6, in which the Ca-O shell radius decrease of about 0.1 Å with respect the hydrated Ca2+ with coordination 8. The experimental results show the OCO angle of the carboxyl in the complex is close to 124°, being the OCaO angle about 60°.

Coordinating a supply chain with price and advertisement dependent stochastic demand.

PubMed

Li, Liying; Wang, Yong; Yan, Xiaoming

2013-01-01

This paper investigates pricing and ordering as well as advertising coordination issues in a single-manufacturer single-retailer supply chain, where the manufacturer sells a newsvendor-type product through the retailer who faces a stochastic demand depending on both retail price and advertising expenditure. Under the assumption that the market demand has a multiplicative functional form, the Stackelberg and cooperative game models are developed, and the closed form solution to each model is provided as well. Comparisons and insights are presented. We show that a properly designed revenue-cost-sharing contract can achieve supply chain coordination and lead to a Pareto improving win-win situation for channel members. We also discuss the allocation of the extra joint profit according to individual supply chain members' risk preferences and negotiating powers.

(N-Benzyl-N-isopropyl­dithio­carbamato)chloridodiphenyl­tin(IV)

PubMed Central

Abdul Muthalib, Amirah Faizah; Baba, Ibrahim; Mohamed Tahir, Mohamed Ibrahim; Ng, Seik Weng; Tiekink, Edward R. T.

2010-01-01

The SnIV atom in the title organotin dithio­carbamate, [Sn(C6H5)2(C11H14NS2)Cl], is penta-coordinated by an asymmetrically coordinating dithio­carbamate ligand, a Cl and two ispo-C atoms of the Sn-bound phenyl groups. The resulting C2ClS2 donor set defines a coordination geometry inter­mediate between square-pyramidal and trigonal-bipyramidal with a slight tendency towards the latter. The formation of close intra­molecular C–H⋯Cl and C–H⋯S contacts precludes the Cl and S atoms from forming significant inter­molecular contacts. The presence of C–H⋯π contacts leads to the formation of supra­molecular arrays that stack along the b axis. PMID:21588504

Evaluation of US Federal Legislation for Opioid Abuse: 1973-2016.

PubMed

Ruble, James H

2016-09-01

The 114th Congress (2014-2016) has received recent attention for the high number of legislative bills directed to the public health crisis in prescription opioid abuse. The US government does not have a single source for determining public policy; however, the people expect that there will be some level of efficiency and coordination between federal and state leaders to improve the nation's health. A search of the National Library of Congress database to analyze legislative bills introduced between 1973 and 2016 and which contain the term "opioid" identified 127 bills that characterize consistency and coordination with other governmental efforts in prescription opioid abuse. Despite the recent number of introduced bills, there does not appear to be a close coordination between Congress and Federal Administrative agencies regarding this crisis.

Are electronic medical records helpful for care coordination? Experiences of physician practices.

PubMed

O'Malley, Ann S; Grossman, Joy M; Cohen, Genna R; Kemper, Nicole M; Pham, Hoangmai H

2010-03-01

Policies promoting widespread adoption of electronic medical records (EMRs) are premised on the hope that they can improve the coordination of care. Yet little is known about whether and how physician practices use current EMRs to facilitate coordination. We examine whether and how practices use commercial EMRs to support coordination tasks and identify work-around practices have created to address new coordination challenges. Semi-structured telephone interviews in 12 randomly selected communities. Sixty respondents, including 52 physicians or staff from 26 practices with commercial ambulatory care EMRs in place for at least 2 years, chief medical officers at four EMR vendors, and four national thought leaders. Six major themes emerged: (1) EMRs facilitate within-office care coordination, chiefly by providing access to data during patient encounters and through electronic messaging; (2) EMRs are less able to support coordination between clinicians and settings, in part due to their design and a lack of standardization of key data elements required for information exchange; (3) managing information overflow from EMRs is a challenge for clinicians; (4) clinicians believe current EMRs cannot adequately capture the medical decision-making process and future care plans to support coordination; (5) realizing EMRs' potential for facilitating coordination requires evolution of practice operational processes; (6) current fee-for-service reimbursement encourages EMR use for documentation of billable events (office visits, procedures) and not of care coordination (which is not a billable activity). There is a gap between policy-makers' expectation of, and clinical practitioners' experience with, current electronic medical records' ability to support coordination of care. Policymakers could expand current health information technology policies to support assessment of how well the technology facilitates tasks necessary for coordination. By reforming payment policy to include care coordination, policymakers could encourage the evolution of EMR technology to include capabilities that support coordination, for example, allowing for inter-practice data exchange and multi-provider clinical decision support.

Coordination-Driven Dimerization of Zinc Chlorophyll Derivatives Possessing a Dialkylamino Group.

PubMed

Watanabe, Hiroaki; Kamatani, Yusuke; Tamiaki, Hitoshi

2017-04-04

Zinc chlorophyll derivatives Zn-1-3 possessing a tertiary amino group at the C3 1 position have been synthesized through reductive amination of methyl pyropheophorbide-d obtained from naturally occurring chlorophyll-a. In a dilute CH 2 Cl 2 solution as well as in a dilute 10 %(v/v) CH 2 Cl 2 /hexane solution, Zn-1 possessing a dimethylamino group at the C3 1 position showed red-shifted UV/Vis absorption and intensified exciton-coupling circular dichroism (CD) spectra at room temperature owing to its dimer formation via coordination to the central zinc by the 3 1 -N atom of the dimethylamino group. However, Zn-2/3 bearing 3 1 -ethylmethylamino/diethylamino groups did not. The difference was dependent on the steric factor of the substituents in the tertiary amino group, where an increase of the carbon numbers on the N atom reduced the intermolecular N⋅⋅⋅Zn coordination. UV/Vis, CD, and 1 H NMR spectroscopic analyses including DOSY measurements revealed that Zn-1 formed closed-type dimers via an opened dimer by single-to-double axial coordination with an increase in concentration and a temperature decrease in CH 2 Cl 2 , while Zn-2/3 gave open and flexible dimers in a concentrated CH 2 Cl 2 solution at low temperature. The supramolecular closed dimer structures of Zn-1 were estimated by molecular modelling calculations, which showed these structures were promising models for the chlorophyll dimer in a photosynthetic reaction center. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

47 CFR 15.525 - Coordination requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... FCC Office of Engineering and Technology, which shall coordinate this information with the Federal... the UWB device. If the imaging device is intended to be used for mobile applications, the geographical...

Coordinated Research Program in Pulsed Power Physics.

DTIC Science & Technology

1984-02-27

storage element and the spark gap sectional area at the injected beam) which helps reduce elec- are both contained within the high pressure vessel of a...ns At the present time the continued research is aimed at duration of the first region corresponds closely to the FWHM answering various unresolved...10-ns e-beam has been used to trigger a spark gap pressurized to 3 atm of N2 . The gap voltage is close to self-breakdown voltage (Le., 0.95 Vb

DEMONSTRATING APPLICATIONS OF REGIONAL VULNERABILITY ASSESSMENT

EPA Science Inventory

This task is designed to respond to 2 Congressional earmarks of $1,000,000 to the Canaan Valley Institute (CVI) to work in close coordination with the Regional Vulnerability Assessment (ReVA) initiative to develop research and educational tools using integrative technologies to p...

The NEAR Spacecraft's Flyby of Asteroid 253 Mathilde

NASA Technical Reports Server (NTRS)

Yeomans, D. K.; Barriot, J. P.; Dunham, D. W.; Farquhar, R. W.; Helfrich, C. E.; Konopliv, A. S.; McAdams, J. V.; Miller, J. K.; Owen, W. M., Jr.; Scheeres, D. J.;

The Ferris Factor.

ERIC Educational Resources Information Center

Wenrich, J. William; Coyle, Tricia

1986-01-01

Examines the close relationship between Ferris State College and Michigan's community colleges and the key role this has played in a coordinated move toward economic revitalization. Describes efforts made in the areas of articulation, prototype vocational programs, admissions counseling, technical education, and the testing and training of…

VASCULAR RESPONSE TO TRAFFIC-DERIVED INHALATION IN HUMANS

EPA Science Inventory

By coordinating closely with Center Projects 1-3, we will determine whether specific aspects of traffic-derived exposure (primary vs. secondary organics, particulate vs. gases, spark-ignition vs. diesel engine vs. a mixture) enhance the human vascular response to pollutants. W...

Irregular Warfare Stability Model (IWSMod)

DTIC Science & Technology

2014-01-01

single shot causing no casualties to a highly coordinated complex attack using two or more weapon systems. Advances in technology have allowed...to power law, the more stable the enviroment . To determine how close the actual distribution is to the power law, the method determines the

7 CFR 1927.54 - Requirements for closing agents.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false Requirements for closing agents. 1927.54 Section 1927... PROGRAM REGULATIONS TITLE CLEARANCE AND LOAN CLOSING Real Estate Title Clearance and Loan Closing § 1927.54 Requirements for closing agents. (a) Form of title certification. State Offices are directed to...

Smc5/6-Mms21 Prevents and Eliminates Inappropriate Recombination Intermediates in Meiosis

PubMed Central

Xaver, Martin; Huang, Lingzhi; Chen, Doris; Klein, Franz

2013-01-01

Repairing broken chromosomes via joint molecule (JM) intermediates is hazardous and therefore strictly controlled in most organisms. Also in budding yeast meiosis, where production of enough crossovers via JMs is imperative, only a subset of DNA breaks are repaired via JMs, closely regulated by the ZMM pathway. The other breaks are repaired to non-crossovers, avoiding JM formation, through pathways that require the BLM/Sgs1 helicase. “Rogue” JMs that escape the ZMM pathway and BLM/Sgs1 are eliminated before metaphase by resolvases like Mus81-Mms4 to prevent chromosome nondisjunction. Here, we report the requirement of Smc5/6-Mms21 for antagonizing rogue JMs via two mechanisms; destabilizing early intermediates and resolving JMs. Elimination of the Mms21 SUMO E3-ligase domain leads to transient JM accumulation, depending on Mus81-Mms4 for resolution. Absence of Smc6 leads to persistent rogue JMs accumulation, preventing chromatin separation. We propose that the Smc5/6-Mms21 complex antagonizes toxic JMs by coordinating helicases and resolvases at D-Loops and HJs, respectively. PMID:24385936

Role of Tim50 in the Transfer of Precursor Proteins from the Outer to the Inner Membrane of Mitochondria

PubMed Central

Sichting, Martin; Popov-Čeleketić, Dušan; Mapa, Koyeli; Gevorkyan-Airapetov, Lada; Zohary, Keren; Hell, Kai; Azem, Abdussalam

2009-01-01

Transport of essentially all matrix and a number of inner membrane proteins is governed, entirely or in part, by N-terminal presequences and requires a coordinated action of the translocases of outer and inner mitochondrial membranes (TOM and TIM23 complexes). Here, we have analyzed Tim50, a subunit of the TIM23 complex that is implicated in transfer of precursors from TOM to TIM23. Tim50 is recruited to the TIM23 complex via Tim23 in an interaction that is essentially independent of the rest of the translocase. We find Tim50 in close proximity to the intermembrane space side of the TOM complex where it recognizes both types of TIM23 substrates, those that are to be transported into the matrix and those destined to the inner membrane, suggesting that Tim50 recognizes presequences. This function of Tim50 depends on its association with TIM23. We conclude that the efficient transfer of precursors between TOM and TIM23 complexes requires the concerted action of Tim50 with Tim23. PMID:19144822

Role of Tim50 in the transfer of precursor proteins from the outer to the inner membrane of mitochondria.

PubMed

Mokranjac, Dejana; Sichting, Martin; Popov-Celeketić, Dusan; Mapa, Koyeli; Gevorkyan-Airapetov, Lada; Zohary, Keren; Hell, Kai; Azem, Abdussalam; Neupert, Walter

2009-03-01

Transport of essentially all matrix and a number of inner membrane proteins is governed, entirely or in part, by N-terminal presequences and requires a coordinated action of the translocases of outer and inner mitochondrial membranes (TOM and TIM23 complexes). Here, we have analyzed Tim50, a subunit of the TIM23 complex that is implicated in transfer of precursors from TOM to TIM23. Tim50 is recruited to the TIM23 complex via Tim23 in an interaction that is essentially independent of the rest of the translocase. We find Tim50 in close proximity to the intermembrane space side of the TOM complex where it recognizes both types of TIM23 substrates, those that are to be transported into the matrix and those destined to the inner membrane, suggesting that Tim50 recognizes presequences. This function of Tim50 depends on its association with TIM23. We conclude that the efficient transfer of precursors between TOM and TIM23 complexes requires the concerted action of Tim50 with Tim23.

Better vaccines for healthier life. Part II. Conference report of the DCVMN International 14th Annual General Meeting Hanoi, Vietnam.

PubMed

Pagliusi, Sonia; Tippoo, Patrick; Sivaramakrishnan, Venkatraman; Nguyen, Thuvan

2014-11-12

New vaccines are required to meet the public health challenges of the next generation and many unmet global health needs can be addressed by developing countries vaccine manufacturers such as lower-cost vaccines based on single-dose, thermostable formulations, efficacious in children with compromised gastrointestinal tracts. GMP compliance is also a challenge, as sometimes innovation and clinical development focus is not accompanied by command of scale-up and quality assurance for large volume manufacturing and supply. Identifying and addressing such challenges, beyond cost and cold-chain space, including safety considerations and health worker behavior, regulatory alliances and harmonization to foster access to vaccines, will help countries to ensure sustainable immunization. There needs to be continuous and close management of the global vaccine supply both at national and international levels, requiring careful risk management, coordination and cooperation with manufacturers. Successful partnership models based on sharing a common goal, mutual respect and good communication were discussed among stakeholders. Copyright © 2014. Published by Elsevier Ltd.. All rights reserved.

Obtaining active parental consent for school-based research: a guide for researchers.

PubMed

Wolfenden, Luke; Kypri, Kypros; Freund, Megan; Hodder, Rebecca

2009-06-01

Schools increasingly require researchers to obtain active parental consent for students to participate in health research. We sought to identify effective strategies for the recruitment of child research participants through schools. A search of Medline, PsycINFO, Educational Resources Information Center, ProQuest 5000 and the Cochrane Library electronic databases was conducted for the period 1988 to 2008. The review found evidence that the following strategies may be effective in enhancing participation rates: 1) promotion of the research to school principals, teachers, parents and students; 2) dissemination of study information using methods allowing direct contact with parents (i.e. telephone or face-to-face); 3) provision of incentives to teachers, students and at a class level; 4) making reminder contacts; and 5) having a member of the research team co-ordinate and closely monitor the recruitment process. Application of these strategies should reduce the risk of non-response and other biases that result from selective non-participation. Further randomised controlled trials of these and other strategies are required to strengthen the evidence base.

Pharmacogenetic studies of antidepressant response: how far from the clinic?

PubMed

Perlis, Roy H

2007-03-01

Because the US FDA has begun to focus on disclosure of pharmacogenetic testing results in applications for new drug approval and review of existing drugs (see, eg, http://www.fda.gov/OHRMS/DOCKETS/AC/05/slides/2005-4194S1_Slide-Index.htm), the application of such testing in a clinical setting is likely to increase substantially. Instead of small cohorts of patients, potentially nearly every participant in the large pivotal trials required for drug approval could help inform the future application of that drug. Psychiatry as a whole, and antidepressant prescribing ni particular, stands to benefit in the near term from the identification of newer treatment targets that may overcome some of the limitations of current therapeutics. On the other hand, despite the excitement about the rapid pace of development in psychiatric pharmacogenetics, a number of key issues remain to be addressed before these discoveries are applied in a clinical setting. Close coordination will be required between those who study treatment efficacy and effectiveness and those who study genetic variation in populations to ensure that studies yield results that have scientific importance and clinical importance as well.

[Enriching the diagnosis announcement system with the coordination passport].

PubMed

Bertrand, Nathalie

2016-05-01

The personalised care plan of a person with cancer requires proper coordination between the various professionals involved in their care at the different stages of their illness. In order to organise this coordination efficiently, for the patient as well as for the health professionals, an oncology hospital team has developed a practical and modular tool. The coordination passport enriches the diagnosis announcement system used in the hospital. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Gaze Stabilization During Locomotion Requires Full Body Coordination

NASA Technical Reports Server (NTRS)

Mulavara, A. P.; Miller, C. A.; Houser, J.; Richards, J. T.; Bloomberg, J. J.

2001-01-01

Maintaining gaze stabilization during locomotion places substantial demands on multiple sensorimotor subsystems for precise coordination. Gaze stabilization during locomotion requires eye-head-trunk coordination (Bloomberg, et al., 1997) as well as the regulation of energy flow or shock-wave transmission through the body at high impact phases with the support surface (McDonald, et al., 1997). Allowing these excessive transmissions of energy to reach the head may compromise gaze stability. Impairments in these mechanisms may lead to the oscillopsia and decreased dynamic visual acuity seen in crewmembers returning from short and long duration spaceflight, as well as in patients with vestibular disorders (Hillman, et al., 1999). Thus, we hypothesize that stabilized gaze during locomotion results from full-body coordination of the eye-head-trunk system combined with the lower limb apparatus. The goal of this study was to determine how multiple, interdependent full- body sensorimotor subsystems aiding gaze stabilization during locomotion are functionally coordinated, and how they adaptively respond to spaceffight.

45 CFR 155.345 - Coordination with Medicaid, CHIP, the Basic Health Program, and the Pre-existing Condition...

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 1 2012-10-01 2012-10-01 false Coordination with Medicaid, CHIP, the Basic Health....345 Coordination with Medicaid, CHIP, the Basic Health Program, and the Pre-existing Condition..., CHIP, and the BHP as are necessary to fulfill the requirements of this subpart and provide copies of...

Communication: Coordinate-dependent diffusivity from single molecule trajectories

NASA Astrophysics Data System (ADS)

Berezhkovskii, Alexander M.; Makarov, Dmitrii E.

2017-11-01

Single-molecule observations of biomolecular folding are commonly interpreted using the model of one-dimensional diffusion along a reaction coordinate, with a coordinate-independent diffusion coefficient. Recent analysis, however, suggests that more general models are required to account for single-molecule measurements performed with high temporal resolution. Here, we consider one such generalization: a model where the diffusion coefficient can be an arbitrary function of the reaction coordinate. Assuming Brownian dynamics along this coordinate, we derive an exact expression for the coordinate-dependent diffusivity in terms of the splitting probability within an arbitrarily chosen interval and the mean transition path time between the interval boundaries. This formula can be used to estimate the effective diffusion coefficient along a reaction coordinate directly from single-molecule trajectories.

Multiple scaling power in liquid gallium under pressure conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Renfeng; Wang, Luhong; Li, Liangliang

Generally, a single scaling exponent, Df, can characterize the fractal structures of metallic glasses according to the scaling power law. However, when the scaling power law is applied to liquid gallium upon compression, the results show multiple scaling exponents and the values are beyond 3 within the first four coordination spheres in real space, indicating that the power law fails to describe the fractal feature in liquid gallium. The increase in the first coordination number with pressure leads to the fact that first coordination spheres at different pressures are not similar to each other in a geometrical sense. This multiplemore » scaling power behavior is confined within a correlation length of ξ ≈ 14–15 Å at applied pressure according to decay of G(r) in liquid gallium. Beyond this length the liquid gallium system could roughly be viewed as homogeneous, as indicated by the scaling exponent, Ds, which is close to 3 beyond the first four coordination spheres.« less

The CEOS Atmospheric Composition Constellation: Enhancing the Value of Space-Based Observations

NASA Technical Reports Server (NTRS)

Eckman, Richard; Zehner, Claus; Al-Saadi, Jay

2015-01-01

The Committee on Earth Observation Satellites (CEOS) coordinates civil space-borne observations of the Earth. Participating agencies strive to enhance international coordination and data exchange and to optimize societal benefit. In recent years, CEOS has collaborated closely with the Group on Earth Observations (GEO) in implementing the Global Earth Observing System of Systems (GEOSS) space-based objectives. The goal of the CEOS Atmospheric Composition Constellation (ACC) is to collect and deliver data to improve monitoring, assessment and predictive capabilities for changes in the ozone layer, air quality and climate forcing associated with changes in the environment through coordination of existing and future international space assets. A project to coordinate and enhance the science value of a future constellation of geostationary sensors measuring parameters relevant to air quality supports the forthcoming European Sentinel-4, Korean GEMS, and US TEMPO missions. Recommendations have been developed for harmonization to mutually improve data quality and facilitate widespread use of the data products.

Orientation congruency effects for familiar objects: coordinate transformations in object recognition.

PubMed

Graf, M; Kaping, D; Bülthoff, H H

2005-03-01

How do observers recognize objects after spatial transformations? Recent neurocomputational models have proposed that object recognition is based on coordinate transformations that align memory and stimulus representations. If the recognition of a misoriented object is achieved by adjusting a coordinate system (or reference frame), then recognition should be facilitated when the object is preceded by a different object in the same orientation. In the two experiments reported here, two objects were presented in brief masked displays that were in close temporal contiguity; the objects were in either congruent or incongruent picture-plane orientations. Results showed that naming accuracy was higher for congruent than for incongruent orientations. The congruency effect was independent of superordinate category membership (Experiment 1) and was found for objects with different main axes of elongation (Experiment 2). The results indicate congruency effects for common familiar objects even when they have dissimilar shapes. These findings are compatible with models in which object recognition is achieved by an adjustment of a perceptual coordinate system.

Coordination of Advanced Solar Observatory (ASO) Science Working Group (SWG) for the study of instrument accommodation and operational requirements on space station

NASA Technical Reports Server (NTRS)

Wu, S. T.

1989-01-01

The objectives are to coordinate the activities of the Science Working Group (SWG) of the Advanced Solar Observatory (ASO) for the study of instruments accommodation and operation requirements on board space station. In order to facilitate the progress of the objective, two conferences were organized, together with two small group discussions.

Coordinate references for the indoor/outdoor seamless positioning

NASA Astrophysics Data System (ADS)

Ruan, Ling; Zhang, Ling; Long, Yi; Cheng, Fei

2018-05-01

Indoor positioning technologies are being developed rapidly, and seamless positioning which connected indoor and outdoor space is a new trend. The indoor and outdoor positioning are not applying the same coordinate system and different indoor positioning scenes uses different indoor local coordinate reference systems. A specific and unified coordinate reference frame is needed as the space basis and premise in seamless positioning application. Trajectory analysis of indoor and outdoor integration also requires a uniform coordinate reference. However, the coordinate reference frame in seamless positioning which can applied to various complex scenarios is lacking of research for a long time. In this paper, we proposed a universal coordinate reference frame in indoor/outdoor seamless positioning. The research focus on analysis and classify the indoor positioning scenes and put forward the coordinate reference system establishment and coordinate transformation methods in each scene. And, through some experiments, the calibration method feasibility was verified.

Strong anticipation and long-range cross-correlation: Application of detrended cross-correlation analysis to human behavioral data

NASA Astrophysics Data System (ADS)

Delignières, Didier; Marmelat, Vivien

2014-01-01

In this paper, we analyze empirical data, accounting for coordination processes between complex systems (bimanual coordination, interpersonal coordination, and synchronization with a fractal metronome), by using a recently proposed method: detrended cross-correlation analysis (DCCA). This work is motivated by the strong anticipation hypothesis, which supposes that coordination between complex systems is not achieved on the basis of local adaptations (i.e., correction, predictions), but results from a more global matching of complexity properties. Indeed, recent experiments have evidenced a very close correlation between the scaling properties of the series produced by two coordinated systems, despite a quite weak local synchronization. We hypothesized that strong anticipation should result in the presence of long-range cross-correlations between the series produced by the two systems. Results allow a detailed analysis of the effects of coordination on the fluctuations of the series produced by the two systems. In the long term, series tend to present similar scaling properties, with clear evidence of long-range cross-correlation. Short-term results strongly depend on the nature of the task. Simulation studies allow disentangling the respective effects of noise and short-term coupling processes on DCCA results, and suggest that the matching of long-term fluctuations could be the result of short-term coupling processes.

Inter-joint coordination strategies during unilateral stance following first-time, acute lateral ankle sprain: A brief report.

PubMed

Doherty, Cailbhe; Bleakley, Chris; Hertel, Jay; Caulfield, Brian; Ryan, John; Sweeney, Kevin; Delahunt, Eamonn

2015-07-01

This investigation combined measures of inter-joint coordination and stabilometry to evaluate eyes-open (condition 1) and eyes-closed (condition 2) static unilateral stance performance in a group of participants with an acute, first-time lateral ankle sprain injury in comparison to a control group. Sixty-six participants with an acute first-time lateral ankle sprain and 19 non-injured controls completed three 20-second unilateral stance task trials in conditions 1 and 2. An adjusted coefficient of multiple determination statistic was used to compare stance limb 3-D kinematic data for similarity in the aim of establishing patterns of inter-joint coordination for these groups. Between-group analyses revealed significant differences in stance limb inter-joint coordination strategies for conditions 1 and 2. Injured participants displayed increases in ankle-hip linked coordination compared to controls in condition 1 (sagittal/frontal plane: 0.12 [0.09] vs 0.06 [0.04]; η(2)=.16) and condition 2 (sagittal/frontal plane: 0.18 [0.13] vs 0.08 [0.06]; η(2)=0.37). Participants with acute first-time lateral ankle sprain exhibit a hip-dominant coordination strategy for static unilateral stance compared to non-injured controls. Copyright © 2015 Elsevier Ltd. All rights reserved.

Heavy Equipment Operator: General Equipment Operator. Instructional Materials.

ERIC Educational Resources Information Center

Hendrix, Laborn J.; Sawatzky, Joyce

Developed through close coordination between contractors, construction workers, and vocational educators, this instructor's manual is designed to help heavy equipment instructors present materials in a systematic format. The instructional materials in the manual are written in terms of student performance, using measurable behavioral objectives.…

Language Nests and Language Acquisition: An Empirical Analysis

ERIC Educational Resources Information Center

Okura, Eve K.

2017-01-01

This dissertation presents the findings from interviews conducted with language nest workers, teachers, language nest coordinators, administrators of language revitalization programs, principals and directors of language immersion schools that work in close proximity with language nests, and linguists involved in language revitalization efforts.…

76 FR 29770 - National Cancer Institute; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-23

... K. Saha, PhD, Scientific Review Officer, Program Coordination and Referral Branch, Division of..., PhD, Scientific Review Officer, Scientific Review and Logistic Branch, Division of Extramural....395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397, Cancer Centers Support; 93...

Geometric interpretation of four-wave mixing

NASA Astrophysics Data System (ADS)

Ott, J. R.; Steffensen, H.; Rottwitt, K.; McKinstrie, C. J.

2013-10-01

The nonlinear phenomenon of four-wave mixing (FWM) is investigated using a method, where, without the need of calculus, both phase and amplitudes of the mixing fields are visualized simultaneously, giving a complete overview of the FWM dynamics. This is done by introducing a set of Stokes-like coordinates of the electric fields, which reduce the FWM dynamics to a closed two-dimensional surface, similar to the Bloch sphere of quantum electrodynamics or the Pointcaré sphere in polarization dynamics. The coordinates are chosen so as to use the gauge invariance symmetries of the FWM equations which also give the conservation of action flux known as the Manley-Rowe relations. This reduces the dynamics of FWM to the one-dimensional intersection between the closed two-dimensional surface and the phase-plane given by the conserved Hamiltonian. The analysis is advantageous for visualizing phase-dependent FWM phenomena which are found in a large variety of nonlinear systems and even in various optical communication schemes.

Polyploidization of glia in neural development links tissue growth to blood-brain barrier integrity.

PubMed

Unhavaithaya, Yingdee; Orr-Weaver, Terry L

2012-01-01

Proper development requires coordination in growth of the cell types composing an organ. Many plant and animal cells are polyploid, but how these polyploid tissues contribute to organ growth is not well understood. We found the Drosophila melanogaster subperineurial glia (SPG) to be polyploid, and ploidy is coordinated with brain mass. Inhibition of SPG polyploidy caused rupture of the septate junctions necessary for the blood-brain barrier. Thus, the increased SPG cell size resulting from polyploidization is required to maintain the SPG envelope surrounding the growing brain. Polyploidization likely is a conserved strategy to coordinate tissue growth during organogenesis, with potential vertebrate examples.

Computer hardware and software for robotic control

NASA Technical Reports Server (NTRS)

Davis, Virgil Leon

1987-01-01

The KSC has implemented an integrated system that coordinates state-of-the-art robotic subsystems. It is a sensor based real-time robotic control system performing operations beyond the capability of an off-the-shelf robot. The integrated system provides real-time closed loop adaptive path control of position and orientation of all six axes of a large robot; enables the implementation of a highly configurable, expandable testbed for sensor system development; and makes several smart distributed control subsystems (robot arm controller, process controller, graphics display, and vision tracking) appear as intelligent peripherals to a supervisory computer coordinating the overall systems.

Vorticity vector-potential method based on time-dependent curvilinear coordinates for two-dimensional rotating flows in closed configurations

NASA Astrophysics Data System (ADS)

Fu, Yuan; Zhang, Da-peng; Xie, Xi-lin

2018-04-01

In this study, a vorticity vector-potential method for two-dimensional viscous incompressible rotating driven flows is developed in the time-dependent curvilinear coordinates. The method is applicable in both inertial and non-inertial frames of reference with the advantage of a fixed and regular calculation domain. The numerical method is applied to triangle and curved triangle configurations in constant and varying rotational angular velocity cases respectively. The evolutions of flow field are studied. The geostrophic effect, unsteady effect and curvature effect on the evolutions are discussed.

Rapid estimation of frequency response functions by close-range photogrammetry

NASA Technical Reports Server (NTRS)

Tripp, J. S.

1985-01-01

The accuracy of a rapid method which estimates the frequency response function from stereoscopic dynamic data is computed. It is shown that reversal of the order of the operations of coordinate transformation and Fourier transformation, which provides a significant increase in computational speed, introduces error. A portion of the error, proportional to the perturbation components normal to the camera focal planes, cannot be eliminated. The remaining error may be eliminated by proper scaling of frequency data prior to coordinate transformation. Methods are developed for least squares estimation of the full 3x3 frequency response matrix for a three dimensional structure.

Communique: Special Issue on the International Scientific Conference and Exhibit and the 7th Session of the International Co-Ordinating Council for MAB (Paris, Sept. 22-Oct. 2, 1981) = Numero special sur la Conference Scientifique Internationale et Exposition et al 7e session du Counseil International de Coordination du MAB (Paris, du 22 Sept. au 2 Oct. 1981).

ERIC Educational Resources Information Center

Communique, 1982

1982-01-01

Presented are summaries of two separate but closely-related conferences. The International Scientific Conference and Exhibit, organized to mark the 10th anniversary of the Man and the Biosphere Program (MAB), was based on the theme "ecology in practice: establishing a scientific basis for land management." This summary includes: a 10…

Vorticity vector-potential method based on time-dependent curvilinear coordinates for two-dimensional rotating flows in closed configurations

NASA Astrophysics Data System (ADS)

Fu, Yuan; Zhang, Da-peng; Xie, Xi-lin

2018-03-01

In this study, a vorticity vector-potential method for two-dimensional viscous incompressible rotating driven flows is developed in the time-dependent curvilinear coordinates. The method is applicable in both inertial and non-inertial frames of reference with the advantage of a fixed and regular calculation domain. The numerical method is applied to triangle and curved triangle configurations in constant and varying rotational angular velocity cases respectively. The evolutions of flow field are studied. The geostrophic effect, unsteady effect and curvature effect on the evolutions are discussed.

Emergence of postural patterns as a function of vision and translation frequency

NASA Technical Reports Server (NTRS)

Buchanan, J. J.; Horak, F. B.; Peterson, B. W. (Principal Investigator)

1999-01-01

Emergence of postural patterns as a function of vision and translation frequency. We examined the frequency characteristics of human postural coordination and the role of visual information in this coordination. Eight healthy adults maintained balance in stance during sinusoidal support surface translations (12 cm peak to peak) in the anterior-posterior direction at six different frequencies. Changes in kinematic and dynamic measures revealed that both sensory and biomechanical constraints limit postural coordination patterns as a function of translation frequency. At slow frequencies (0.1 and 0.25 Hz), subjects ride the platform (with the eyes open or closed). For fast frequencies (1.0 and 1.25 Hz) with the eyes open, subjects fix their head and upper trunk in space. With the eyes closed, large-amplitude, slow-sway motion of the head and trunk occurred for fast frequencies above 0.5 Hz. Visual information stabilized posture by reducing the variability of the head's position in space and the position of the center of mass (CoM) within the support surface defined by the feet for all but the slowest translation frequencies. When subjects rode the platform, there was little oscillatory joint motion, with muscle activity limited mostly to the ankles. To support the head fixed in space and slow-sway postural patterns, subjects produced stable interjoint hip and ankle joint coordination patterns. This increase in joint motion of the lower body dissipated the energy input by fast translation frequencies and facilitated the control of upper body motion. CoM amplitude decreased with increasing translation frequency, whereas the center of pressure amplitude increased with increasing translation frequency. Our results suggest that visual information was important to maintaining a fixed position of the head and trunk in space, whereas proprioceptive information was sufficient to produce stable coordinative patterns between the support surface and legs. The CNS organizes postural patterns in this balance task as a function of available sensory information, biomechanical constraints, and translation frequency.

Patient, Primary Care Provider, and Specialist Perspectives on Specialty Care Coordination in an Integrated Health Care System.

PubMed

Vimalananda, Varsha G; Dvorin, Kelly; Fincke, B Graeme; Tardiff, Nicole; Bokhour, Barbara G

Successful coordination of specialty care requires understanding the perspectives of patients, primary care providers, and specialists-that is, the specialty care "triad." This study used qualitative methods to compare these perspectives in an integrated health care system, using diabetes specialty care as an exemplar. Primary care providers and endocrinologists relied on interclinician relationships to coordinate care. Clinicians rarely included patients or other staff in their conceptualization of specialty care coordination. Patients often assumed responsibility for specialty care coordination but struggled to succeed. We identified several opportunities to improve coordination across the triad. In an integrated medical system, the shared organizational structure can facilitate these efforts.

On-field mounting position estimation of a lidar sensor

NASA Astrophysics Data System (ADS)

Khan, Owes; Bergelt, René; Hardt, Wolfram

2017-10-01

In order to retrieve a highly accurate view of their environment, autonomous cars are often equipped with LiDAR sensors. These sensors deliver a three dimensional point cloud in their own co-ordinate frame, where the origin is the sensor itself. However, the common co-ordinate system required by HAD (Highly Autonomous Driving) software systems has its origin at the center of the vehicle's rear axle. Thus, a transformation of the acquired point clouds to car co-ordinates is necessary, and thereby the determination of the exact mounting position of the LiDAR system in car coordinates is required. Unfortunately, directly measuring this position is a time-consuming and error-prone task. Therefore, different approaches have been suggested for its estimation which mostly require an exhaustive test-setup and are again time-consuming to prepare. When preparing a high number of LiDAR mounted test vehicles for data acquisition, most approaches fall short due to time or money constraints. In this paper we propose an approach for mounting position estimation which features an easy execution and setup, thus making it feasible for on-field calibration.

Effect of altered sensory conditions on multivariate descriptors of human postural sway

NASA Technical Reports Server (NTRS)

Kuo, A. D.; Speers, R. A.; Peterka, R. J.; Horak, F. B.; Peterson, B. W. (Principal Investigator)

1998-01-01

Multivariate descriptors of sway were used to test whether altered sensory conditions result not only in changes in amount of sway but also in postural coordination. Eigenvalues and directions of eigenvectors of the covariance of shnk and hip angles were used as a set of multivariate descriptors. These quantities were measured in 14 healthy adult subjects performing the Sensory Organization test, which disrupts visual and somatosensory information used for spatial orientation. Multivariate analysis of variance and discriminant analysis showed that resulting sway changes were at least bivariate in character, with visual and somatosensory conditions producing distinct changes in postural coordination. The most significant changes were found when somatosensory information was disrupted by sway-referencing of the support surface (P = 3.2 x 10(-10)). The resulting covariance measurements showed that subjects not only swayed more but also used increased hip motion analogous to the hip strategy. Disruption of vision, by either closing the eyes or sway-referencing the visual surround, also resulted in altered sway (P = 1.7 x 10(-10)), with proportionately more motion of the center of mass than with platform sway-referencing. As shown by discriminant analysis, an optimal univariate measure could explain at most 90% of the behavior due to altered sensory conditions. The remaining 10%, while smaller, are highly significant changes in posture control that depend on sensory conditions. The results imply that normal postural coordination of the trunk and legs requires both somatosensory and visual information and that each sensory modality makes a unique contribution to posture control. Descending postural commands are multivariate in nature, and the motion at each joint is affected uniquely by input from multiple sensors.

Spatiotemporal movement planning and rapid adaptation for manual interaction.

PubMed

Huber, Markus; Kupferberg, Aleksandra; Lenz, Claus; Knoll, Alois; Brandt, Thomas; Glasauer, Stefan

2013-01-01

Many everyday tasks require the ability of two or more individuals to coordinate their actions with others to increase efficiency. Such an increase in efficiency can often be observed even after only very few trials. Previous work suggests that such behavioral adaptation can be explained within a probabilistic framework that integrates sensory input and prior experience. Even though higher cognitive abilities such as intention recognition have been described as probabilistic estimation depending on an internal model of the other agent, it is not clear whether much simpler daily interaction is consistent with a probabilistic framework. Here, we investigate whether the mechanisms underlying efficient coordination during manual interactions can be understood as probabilistic optimization. For this purpose we studied in several experiments a simple manual handover task concentrating on the action of the receiver. We found that the duration until the receiver reacts to the handover decreases over trials, but strongly depends on the position of the handover. We then replaced the human deliverer by different types of robots to further investigate the influence of the delivering movement on the reaction of the receiver. Durations were found to depend on movement kinematics and the robot's joint configuration. Modeling the task was based on the assumption that the receiver's decision to act is based on the accumulated evidence for a specific handover position. The evidence for this handover position is collected from observing the hand movement of the deliverer over time and, if appropriate, by integrating this sensory likelihood with prior expectation that is updated over trials. The close match of model simulations and experimental results shows that the efficiency of handover coordination can be explained by an adaptive probabilistic fusion of a-priori expectation and online estimation.

Administrative issues involved in disaster management in India.

PubMed

Kaur, Jagdish

2006-12-01

India as a country is vulnerable to a number of disasters, from earthquakes to floods. Poor and weaker members of the society have always been more vulnerable to various types of disasters. Disasters result in unacceptably high morbidity and mortality amongst the affected population. Damage to infrastructure and reduction in revenues from the affected region due to low yield add to the economic losses. Poor co-ordination at the local level, lack of early-warning systems, often very slow responses, paucity of trained dedicated clinicians, lack of search and rescue facilities and poor community empowerment are some of the factors, which have been contributing to poor response following disasters in the past. The first formal step towards development of policies relating to disaster care in India was the formulation of the National Disaster Response Plan (NDRP) which was formulated initially by the Government of India for managing natural disasters only. However, this was subsequently amended to include man-made disasters as well. It sets the scene for formulating state and district level plans in all states to bring cohesiveness and a degree of uniform management in dealing with disasters. A National Disaster Management Authority has been constituted which aims to provide national guidelines and is headed by the Prime Minister of India. It is the highest decision-making body for the management of disasters in the country. The authority has the responsibility for co-ordinating response and post-disaster relief and rehabilitation. Each state is required to set up Disaster Management Authorities and District Disaster Management Committees for co-ordination and close supervision of activities and efforts related to the management of disasters.

Executive function plays a role in coordinating different perspectives, particularly when one's own perspective is involved.

PubMed

Fizke, Ella; Barthel, Dana; Peters, Thomas; Rakoczy, Hannes

2014-03-01

While developmental experiments with children and elderly subjects, work with neuropsychological patients and adult experimental studies have consistently found close relations between executive function and theory of mind, the foundation of this relation still remains somewhat unclear. One prominent account holds that executive function is specifically involved in ascribing such mental states, paradigmatically beliefs, that aim at representing the world truly because ascribing such states requires inhibition of normative defaults (beliefs being true) (e.g. Sabbagh, Moses, & Shiverick, 2006). The present studies systematically tested for the role of executive function in different forms of mental state ascription as a function of the type of state ascribed (beliefs or desires) and the first person involvement of the ascriber (whether she herself has an attitude conflicting with one to be ascribed to someone else) in young children. The results reveal that (i) executive function is related not only to belief ascription but equally to desire ascription when both are matched in terms of logical complexity (such that two subjective attitudes have to be ascribed to two agents that are incompatible with each other). (ii) Both for desires and for beliefs, these relations are strongest in such tasks where the ascriber herself is one of the two agents, i.e. has a belief or desire herself that stands in contrast to that to be ascribed to someone else. All in all, these findings suggest that executive function figures in coordinating perspectives more generally, not only epistemic ones, and in particular in coordinating others' and one's own conflicting perspectives. Copyright © 2013 Elsevier B.V. All rights reserved.

An information management system for patients with tuberculosis: usability assessment with end-users.

PubMed

Darby, Jonathan; Black, Jim; Morrison, David; Buising, Kirsty

2012-01-01

Information systems with clinical decision support (CDS) offer great potential to assist the co-ordination of patients with chronic diseases and to improve patient care. Despite this, few have entered routine clinical use. Tuberculosis (TB) is an infection of public health importance. It has complex interactions with many comorbid conditions, requires close supervised care and prolonged treatment for effective cure. These features make it suitable for use with an information management system with CDS features. In close consultation with key stakeholders, a clinical application was developed for the management of TB patients in Victoria. A formal usability assessment using semi-structured case-scenario based exercises was performed. Subjects were 12 individuals closely involved in the care of TB patients, including Infectious Diseases and Respiratory Physicians, and Public Health Nurses. Two researchers conducted the sessions, independently analysed responses and discrepancies compared to the voice record for validity. Despite varied computer experience, responses were positive regarding user interface and content. Data location was not always intuitive, however this improved with familiarity of the program. Decision support was considered valuable, with useful suggestions for expansion of these features. Automated reporting for correspondence and notification to the Health Department were felt worth the initial investment in data entry. An important workflow-based issue regarding dismissal of alerts and several errors were detected. Usability assessment validated many design elements of the system, provided a unique insight into workflow issues faced by users and hopefully will impact on its ultimate clinical utility.

Strengthening the Signature Pedagogy of Social Work: Conceptualizing Field Coordination as a Negotiated Social Work Pedagogy

ERIC Educational Resources Information Center

Asakura, Kenta; Todd, Sarah; Eagle, Brooke; Morris, Brenda

2018-01-01

Although field education is considered the signature pedagogy of social work, the work of field coordinators appear to remain peripheral to other aspects of social work education, such as coursework and research. In this article, we suggest that field coordination requires a far more complex set of knowledge and skills than merely matching…

Does the Coordination of Verbal and Motor Information Explain the Development of Counting in Children?

ERIC Educational Resources Information Center

Camos, Valerie; Barrouillet, Pierre; Fayol, Michel

2001-01-01

Tested in three experiments hypothesis that coordinating saying number-words and pointing to each object to count requires use of the central executive and that cost of coordination decreases with age. Found that for 5- and 9-year-olds and adults, manipulating difficulty of each component affected counting performance but did not make coordination…

Feature integration in visual working memory: parietal gamma activity is related to cognitive coordination

PubMed Central

Muthukumaraswamy, Suresh D.; Hibbs, Carina S.; Shapiro, Kimron L.; Bracewell, R. Martyn; Singh, Krish D.; Linden, David E. J.

2011-01-01

The mechanism by which distinct subprocesses in the brain are coordinated is a central conundrum of systems neuroscience. The parietal lobe is thought to play a key role in visual feature integration, and oscillatory activity in the gamma frequency range has been associated with perception of coherent objects and other tasks requiring neural coordination. Here, we examined the neural correlates of integrating mental representations in working memory and hypothesized that parietal gamma activity would be related to the success of cognitive coordination. Working memory is a classic example of a cognitive operation that requires the coordinated processing of different types of information and the contribution of multiple cognitive domains. Using magnetoencephalography (MEG), we report parietal activity in the high gamma (80–100 Hz) range during manipulation of visual and spatial information (colors and angles) in working memory. This parietal gamma activity was significantly higher during manipulation of visual-spatial conjunctions compared with single features. Furthermore, gamma activity correlated with successful performance during the conjunction task but not during the component tasks. Cortical gamma activity in parietal cortex may therefore play a role in cognitive coordination. PMID:21940605

Assessing Space Exploration Technology Requirements as a First Step Towards Ensuring Technology Readiness for International Cooperation in Space Exploration

NASA Technical Reports Server (NTRS)

Laurini, Kathleen C.; Hufenbach, Bernhard; Satoh, Maoki; Piedboeuf, Jean-Claude; Neumann, Benjamin

2010-01-01

Advancing critical and enhancing technologies is considered essential to enabling sustainable and affordable human space exploration. Critical technologies are those that enable a certain class of mission, such as technologies necessary for safe landing on the Martian surface, advanced propulsion, and closed loop life support. Others enhance the mission by leading to a greater satisfaction of mission objectives or increased probability of mission success. Advanced technologies are needed to reduce mass and cost. Many space agencies have studied exploration mission architectures and scenarios with the resulting lists of critical and enhancing technologies being very similar. With this in mind, and with the recognition that human space exploration will only be enabled by agencies working together to address these challenges, interested agencies participating in the International Space Exploration Coordination Group (ISECG) have agreed to perform a technology assessment as an important step in exploring cooperation opportunities for future exploration mission scenarios. "The Global Exploration Strategy: The Framework for Coordination" was developed by fourteen space agencies and released in May 2007. Since the fall of 2008, several International Space Exploration Coordination Group (ISECG) participating space agencies have been studying concepts for human exploration of the moon. They have identified technologies considered critical and enhancing of sustainable space exploration. Technologies such as in-situ resource utilization, advanced power generation/energy storage systems, reliable dust resistant mobility systems, and closed loop life support systems are important examples. Similarly, agencies such as NASA, ESA, and Russia have studied Mars exploration missions and identified critical technologies. They recognize that human and robotic precursor missions to destinations such as LEO, moon, and near earth objects provide opportunities to demonstrate the technologies needed for Mars mission. Agencies see the importance of assessing gaps and overlaps in their plans to advance technologies in order to leverage their investments and enable exciting missions as soon as practical. They see the importance of respecting the ability of any agency to invest in any technologies considered interesting or strategic. This paper will describe the importance of developing an appropriate international strategy for technology development and ideas for effective mechanisms for advancing an international strategy. This work will both inform and be informed by the development of an ISECG Global Exploration Roadmap and serve as a concrete step forward in advancing the Global Exploration Strategy.

Sensor module design and forward and inverse kinematics analysis of 6-DOF sorting transferring robot

NASA Astrophysics Data System (ADS)

Zhou, Huiying; Lin, Jiajian; Liu, Lei; Tao, Meng

2017-09-01

To meet the demand of high strength express sorting, it is significant to design a robot with multiple degrees of freedom that can sort and transfer. This paper uses infrared sensor, color sensor and pressure sensor to receive external information, combine the plan of motion path in advance and the feedback information from the sensors, then write relevant program. In accordance with these, we can design a 6-DOF robot that can realize multi-angle seizing. In order to obtain characteristics of forward and inverse kinematics, this paper describes the coordinate directions and pose estimation by the D-H parameter method and closed solution. On the basis of the solution of forward and inverse kinematics, geometric parameters of links and link parameters are optimized in terms of application requirements. In this way, this robot can identify route, sort and transfer.

Physiological motion modeling for organ-mounted robots.

PubMed

Wood, Nathan A; Schwartzman, David; Zenati, Marco A; Riviere, Cameron N

2017-12-01

Organ-mounted robots passively compensate heartbeat and respiratory motion. In model-guided procedures, this motion can be a significant source of information that can be used to aid in localization or to add dynamic information to static preoperative maps. Models for estimating periodic motion are proposed for both position and orientation. These models are then tested on animal data and optimal orders are identified. Finally, methods for online identification are demonstrated. Models using exponential coordinates and Euler-angle parameterizations are as accurate as models using quaternion representations, yet require a quarter fewer parameters. Models which incorporate more than four cardiac or three respiration harmonics are no more accurate. Finally, online methods estimate model parameters as accurately as offline methods within three respiration cycles. These methods provide a complete framework for accurately modelling the periodic deformation of points anywhere on the surface of the heart in a closed chest. Copyright © 2017 John Wiley & Sons, Ltd.

Development of a New De Novo Design Algorithm for Exploring Chemical Space.

PubMed

Mishima, Kazuaki; Kaneko, Hiromasa; Funatsu, Kimito

2014-12-01

In the first stage of development of new drugs, various lead compounds with high activity are required. To design such compounds, we focus on chemical space defined by structural descriptors. New compounds close to areas where highly active compounds exist will show the same degree of activity. We have developed a new de novo design system to search a target area in chemical space. First, highly active compounds are manually selected as initial seeds. Then, the seeds are entered into our system, and structures slightly different from the seeds are generated and pooled. Next, seeds are selected from the new structure pool based on the distance from target coordinates on the map. To test the algorithm, we used two datasets of ligand binding affinity and showed that the proposed generator could produce diverse virtual compounds that had high activity in docking simulations. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Unmet needs of children with special health care needs in a specialized day school setting.

PubMed

Aruda, Mary M; Kelly, Mary; Newinsky, Karina

2011-06-01

Children with Special Health Care Needs (CSHCN) represent a significant component of the pediatric population. They often present to schools with multiple and increasingly complex health issues, including medical technology dependency. Their daily variation in health status requires close monitoring and communication among caregivers. Limited research exists regarding parental concerns and communication between health providers, schools, and families. This study identifies the concerns of parents with CSHCN families, including satisfaction with communication between medical providers and schools. Parents completed a survey adapted from the American Academy of Pediatrics (AAP). Analysis of data indicated a high utilization of primary care services but highlighted persistent difficulty accessing services. This study demonstrates families have basic unmet needs in attaining services, including respite and palliative care; indicated an interest in improved communication and coordination of health information between schools and their primary health care providers; and expressed interest in augmenting school health services.

Analytic studies of local-severe-storm observables by satellites

NASA Technical Reports Server (NTRS)

Dergarabedian, P.; Fendell, F.

1977-01-01

Attention is concentrated on the exceptionally violet whirlwind, often characterized by a fairly vertical axis of rotation. For a cylindrical polar coordinate system with axis coincident with the axis of rotation, the secondary flow involves the radial and axial velocity components. The thesis advanced is, first, that a violent whirlwind is characterized by swirl speeds relative to the axis of rotation on the order of 90 m/s, with 100 m/s being close to an upper bound. This estimate is based on interpretation of funnel-cloud shape (which also suggests properties of the radial profile of swirl, as well as the maximum magnitude); an error assessment of the funnel-cloud interpretation procedure is developed. Second, computation of ground-level pressure deficits achievable from typical tornado-spawning ambients by idealized thermohydrostatic processes suggests that a two-cell structure is required to sustain such large speeds.

Amnioserosa cell constriction but not epidermal actin cable tension autonomously drives dorsal closure.

PubMed

Pasakarnis, Laurynas; Frei, Erich; Caussinus, Emmanuel; Affolter, Markus; Brunner, Damian

2016-11-01

Tissue morphogenesis requires coordination of multiple force-producing components. During dorsal closure in fly embryogenesis, an epidermis opening closes. A tensioned epidermal actin/MyosinII cable, which surrounds the opening, produces a force that is thought to combine with another MyosinII force mediating apical constriction of the amnioserosa cells that fill the opening. A model proposing that each force could autonomously drive dorsal closure was recently challenged by a model in which the two forces combine in a ratchet mechanism. Acute force elimination via selective MyosinII depletion in one or the other tissue shows that the amnioserosa tissue autonomously drives dorsal closure while the actin/MyosinII cable cannot. These findings exclude both previous models, although a contribution of the ratchet mechanism at dorsal closure onset remains likely. This shifts the current view of dorsal closure being a combinatorial force-component system to a single tissue-driven closure event.

A new approach to promoting sluggish Diels-Alder reactions: dihapto-coordination of the diene.

PubMed

Liu, Weijun; You, Fei; Mocella, Christopher J; Harman, W Dean

2006-02-08

The cycloaddition between 1,3-cyclohexadiene and various enones and enals (methyl vinyl ketone, ethyl vinyl ketone, methacrolien) is accomplished at room temperature in yields ranging from 51 to 68% without the use of Lewis acids, high pressures, or microwave reactors. This normally sluggish cyclization is accomplished by precoordination of the diene to a pi-basic molybdenum complex. The eta2-bound metal is thought to promote a Michael reaction between the uncoordinated portion of the diene and the enone, and the resulting enolate then closes to form the cycloalkene product. The organic cycloadduct is removed by oxidation with air or with silver triflate in nearly quantitative yield. For more sterically hindered enones (e.g., mesityl oxide) and for methyl acrylate, the desired outcome requires the use of BF3.OEt2, and yields are significantly lower (15-35%)

Defence R&D Canada's autonomous intelligent systems program

NASA Astrophysics Data System (ADS)

Digney, Bruce L.; Hubbard, Paul; Gagnon, Eric; Lauzon, Marc; Rabbath, Camille; Beckman, Blake; Collier, Jack A.; Penzes, Steven G.; Broten, Gregory S.; Monckton, Simon P.; Trentini, Michael; Kim, Bumsoo; Farell, Philip; Hopkin, Dave

2004-09-01

The Defence Research and Development Canada's (DRDC has been given strategic direction to pursue research to increase the independence and effectiveness of military vehicles and systems. This has led to the creation of the Autonomous Intelligent Systems (AIS) prgram and is notionally divide into air, land and marine vehicle systems as well as command, control and decision support systems. This paper presents an overarching description of AIS research issues, challenges and directions as well as a nominal path that vehicle intelligence will take. The AIS program requires a very close coordination between research and implementation on real vehicles. This paper briefly discusses the symbiotic relationship between intelligence algorithms and implementation mechanisms. Also presented are representative work from two vehicle specific research program programs. Work from the Autonomous Air Systems program discusses the development of effective cooperate control for multiple air vehicle. The Autonomous Land Systems program discusses its developments in platform and ground vehicle intelligence.

Metrology requirements for the serial production of ELT primary mirror segments

NASA Astrophysics Data System (ADS)

Rees, Paul C. T.; Gray, Caroline

2015-08-01

The manufacture of the next generation of large astronomical telescopes, the extremely large telescopes (ELT), requires the rapid manufacture of greater than 500 1.44m hexagonal segments for the primary mirror of each telescope. Both leading projects, the Thirty Meter Telescope (TMT) and the European Extremely Large Telescope (E-ELT), have set highly demanding technical requirements for each fabricated segment. These technical requirements, when combined with the anticipated construction schedule for each telescope, suggest that more than one optical fabricator will be involved in the delivery of the primary mirror segments in order to meet the project schedule. For one supplier, the technical specification is challenging and requires highly consistent control of metrology in close coordination with the polishing technologies used in order to optimize production rates. For production using multiple suppliers, however the supply chain is structured, consistent control of metrology along the supply chain will be required. This requires a broader pattern of independent verification than is the case of a single supplier. This paper outlines the metrology requirements for a single supplier throughout all stages of the fabrication process. We identify and outline those areas where metrology accuracy and duration have a significant impact on production efficiency. We use the challenging ESO E-ELT technical specification as an example of our treatment, including actual process data. We further develop this model for the case of a supply chain consisting of multiple suppliers. Here, we emphasize the need to control metrology throughout the supply chain in order to optimize net production efficiency.

Gene dosage imbalance during DNA replication controls bacterial cell-fate decision

NASA Astrophysics Data System (ADS)

Igoshin, Oleg

Genes encoding proteins in a common regulatory network are frequently located close to one another on the chromosome to facilitate co-regulation or couple gene expression to growth rate. Contrasting with these observations, here we demonstrate a functional role for the arrangement of Bacillus subtilis sporulation network genes on opposite sides of the chromosome. We show that the arrangement of two sporulation network genes, one located close to the origin, the other close to the terminus leads to a transient gene dosage imbalance during chromosome replication. This imbalance is detected by the sporulation network to produce cell-cycle coordinated pulses of the sporulation master regulator Spo0A~P. This pulsed response allows cells to decide between sporulation and continued vegetative growth during each cell-cycle spent in starvation. Furthermore, changes in DNA replication and cell-cycle parameters with decreased growth rate in starvation conditions enable cells to indirectly detect starvation without the need for evaluating specific metabolites. The simplicity of the uncovered coordination mechanism and starvation sensing suggests that it may be widely applicable in a variety of gene regulatory and stress-response settings. This work is supported by National Science Foundation Grants MCB-1244135, EAGER-1450867, MCB-1244423, NIH NIGMS Grant R01 GM088428 and HHMI International Student Fellowship.

Pediatric Care Coordination: Lessons Learned and Future Priorities.

PubMed

Cady, Rhonda G; Looman, Wendy S; Lindeke, Linda L; LaPlante, Bonnie; Lundeen, Barbara; Seeley, Amanda; Kautto, Mary E

2015-09-30

A fundamental component of the medical home model is care coordination. In Minnesota, this model informed design and implementation of the state's health care home (HCH) model, a key element of statewide healthcare reform legislation. Children with medical complexity (CMC) often require care from multiple specialists and community resources. Coordinating this multi-faceted care within the HCH is challenging. This article describes the need for specialized models of care coordination for CMC. Two models of care coordination for CMC were developed to address this challenge. The TeleFamilies Model of Pediatric Care Coordination uses an advanced practice registered nurse care (APRN) coordinator embedded within an established HCH. The PRoSPer Model of Pediatric Care Coordination uses a registered nurse/social worker care coordinator team embedded within a specialty care system. We describe key findings from implementation of these models, and conclude with lessons learned. Replication of the models is encouraged to increase the evidence base for care coordination for the growing population of children with medical complexities.

Premature infant swallowing: patterns of tongue-soft palate coordination based upon videofluoroscopy.

PubMed

Goldfield, Eugene C; Buonomo, Carlo; Fletcher, Kara; Perez, Jennifer; Margetts, Stacey; Hansen, Anne; Smith, Vincent; Ringer, Steven; Richardson, Michael J; Wolff, Peter H

2010-04-01

Coordination between movements of individual tongue points, and between soft palate elevation and tongue movements, were examined in 12 prematurely born infants referred from hospital NICUs for videofluoroscopic swallow study (VFSS) due to poor oral feeding and suspicion of aspiration. Detailed post-evaluation kinematic analysis was conducted by digitizing images of a lateral view of digitally superimposed points on the tongue and soft palate. The primary measure of coordination was continuous relative phase of the time series created by movements of points on the tongue and soft palate over successive frames. Three points on the tongue (anterior, medial, and posterior) were organized around a stable in-phase pattern, with a phase lag that implied an anterior to posterior direction of motion. Coordination between a tongue point and a point on the soft palate during lowering and elevation was close to anti-phase at initiation of the pharyngeal swallow. These findings suggest that anti-phase coordination between tongue and soft palate may reflect the process by which the tongue is timed to pump liquid by moving it into an enclosed space, compressing it, and allowing it to leave by a specific route through the pharynx. Copyright 2009 Elsevier Inc. All rights reserved.

Perceptions of bicycle-friendly policy impacts on accessibility to transit services : the first and last mile bridge.

DOT National Transportation Integrated Search

2014-01-01

The coordination of bicycle and transit modes has received close attention from public transit planners and researchers in recent years, as transit agencies around the world have installed bicycle racks on transit vehicles, implemented bicycles-on-tr...

Heavy Equipment Operator Instructional Materials. Basic Core. Volume I.

ERIC Educational Resources Information Center

Hendrix, Laborn J.; Sawatzky, Joyce

Developed through close coordination between contractors, construction workers, and vocational educators, this instructor's manual is designed to help heavy equipment instructors present materials in a systematic format. The instructional materials in the manual are written in terms of student performance, using measurable behavioral objectives.…

77 FR 60445 - Office of the Director, National Institutes of Health; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-03

... Training Award; 93.22, Clinical Research Loan Repayment Program for Individuals from Disadvantaged...; 93.936, NIH Acquired Immunodeficiency Syndrome Research Loan Repayment Program; 93.187, Undergraduate... of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, NIH, Building 1...

Cooperation between Magnesium and Metabolite Controls Collapse of the SAM-I Riboswitch.

PubMed

Roy, Susmita; Onuchic, José N; Sanbonmatsu, Karissa Y

2017-07-25

The S-adenosylmethionine (SAM)-I riboswitch is a noncoding RNA that regulates the transcription termination process in response to metabolite (SAM) binding. The aptamer portion of the riboswitch may adopt an open or closed state depending on the presence of metabolite. Although the transition between the open and closed states is critical for the switching process, its atomistic details are not well understood. Using atomistic simulations, we calculate the effect of SAM and magnesium ions on the folding free energy landscape of the SAM-I riboswitch. These molecular simulation results are consistent with our previous wetlab experiments and aid in interpreting the SHAPE probing measurements. Here, molecular dynamics simulations explicitly identify target RNA motifs sensitive to magnesium ions and SAM. In the simulations, we observe that, whereas the metabolite mostly stabilizes the P1 and P3 helices, magnesium serves an important role in stabilizing a pseudoknot interaction between the P2 and P4 helices, even at high metabolite concentrations. The pseudoknot stabilization by magnesium, in combination with P1 stabilization by SAM, explains the requirement of both SAM and magnesium to form the fully collapsed metabolite-bound closed state of the SAM-I riboswitch. In the absence of SAM, frequent open-to-closed conformational transitions of the pseudoknot occur, akin to breathing. These pseudoknot fluctuations disrupt the binding site by facilitating fluctuations in the 5'-end of helix P1. Magnesium biases the landscape toward a collapsed state (preorganization) by coordinating pseudoknot and 5'-P1 fluctuations. The cooperation between SAM and magnesium in stabilizing important tertiary interactions elucidates their functional significance in transcription regulation. Published by Elsevier Inc.

Innovation in organ transplantation: A meeting report.

PubMed

Fishman, Jay A; Greenwald, Melissa

2018-05-09

This workshop targeted opportunities to stimulate transformative innovation in organ transplantation. Participants reached consensus regarding the following: (1) Mechanisms are needed to improve the coordination of policy and oversight activities, given overlapping responsibilities for transplantation and clinical investigation among federal agencies. Innovative clinical trials span traditional administrative boundaries and include stakeholders with diverse interests. Participants identified the need for a governmental interagency working group to coordinate nationwide transplant-related activities. (2) Improvements are required in clinical metrics for transplantation, with alignment of performance goals across transplantation organizations and any development of data requirements being consistent with those goals. Database coordination among clinical centers, organ procurement organizations, regulatory agencies, and payers would facilitate research and better inform policy. New data requirements should provide actionable insights into clinical performance. (3) Innovative research seen as potentially adversely affecting Program-Specific Reports may reduce centers' participation. Cutting-edge research requires mitigation of risk-aversive behaviors created by reporting of clinical outcomes data. Participants proposed a new review process in advance of implementation of clinical trials to guide "carve-outs" of transplant center outcomes data from Program-Specific Reports. Clinical transplantation will be advanced by the development of a shared and comprehensive research agenda to facilitate coordination of research and policy. © 2018 The American Society of Transplantation and the American Society of Transplant Surgeons.

Multiple Openings and Competitiveness of Forward Markets: Experimental Evidence

PubMed Central

Ferreira, José Luis; Kujal, Praveen; Rassenti, Stephen

2016-01-01

We test the competition enhancing effect of selling forward in experimental Cournot duopoly and quadropoly with multiple forward markets. We find that two forward periods yields competitive outcomes and that the results are very close to the predicted theoretical results for quantity setting duopolies and quadropolies. Our experiments lend strong support to the hypothesis that forward markets are competition enhancing. We then test a new market that allows for endogenously determined indefinitely many forward periods that only close when sellers coordinate on selling a zero amount in a forward market. We find that the outcomes under an endogenous close rule are also very competitive. These results hold for both duopolies and quadropolies. PMID:27442516

Coordination of Hepatitis C Virus Assembly by Distinct Regulatory Regions in Nonstructural Protein 5A

PubMed Central

Zayas, Margarita; Long, Gang; Madan, Vanesa; Bartenschlager, Ralf

2016-01-01

Hepatitis C virus (HCV) nonstructural protein (NS)5A is a RNA-binding protein composed of a N-terminal membrane anchor, a structured domain I (DI) and two intrinsically disordered domains (DII and DIII) interacting with viral and cellular proteins. While DI and DII are essential for RNA replication, DIII is required for assembly. How these processes are orchestrated by NS5A is poorly understood. In this study, we identified a highly conserved basic cluster (BC) at the N-terminus of DIII that is critical for particle assembly. We generated BC mutants and compared them with mutants that are blocked at different stages of the assembly process: a NS5A serine cluster (SC) mutant blocked in NS5A-core interaction and a mutant lacking the envelope glycoproteins (ΔE1E2). We found that BC mutations did not affect core-NS5A interaction, but strongly impaired core–RNA association as well as virus particle envelopment. Moreover, BC mutations impaired RNA-NS5A interaction arguing that the BC might be required for loading of core protein with viral RNA. Interestingly, RNA-core interaction was also reduced with the ΔE1E2 mutant, suggesting that nucleocapsid formation and envelopment are coupled. These findings argue for two NS5A DIII determinants regulating assembly at distinct, but closely linked steps: (i) SC-dependent recruitment of replication complexes to core protein and (ii) BC-dependent RNA genome delivery to core protein, triggering encapsidation that is tightly coupled to particle envelopment. These results provide a striking example how a single viral protein exerts multiple functions to coordinate the steps from RNA replication to the assembly of infectious virus particles. PMID:26727512

System analysis tools for an ELT at ESO

NASA Astrophysics Data System (ADS)

Mueller, Michael; Koch, Franz

2006-06-01

Engineering of complex, large scale systems like the ELT designs currently investigated and developed in Europe and Northern America require powerful and sophisticated tools within specific technical disciplines such as mechanics, optics and control engineering. However, even analyzing a certain component of the telescope like the telescope structure necessitates a system approach to evaluate the structural effects onto the optical performance. This paper shows several software tools developed by the European Southern Observatory (ESO) which focus onto the system approach in the analyses: Using modal results of a finite element analysis the SMI-toolbox allows an easy generation of structural models with different sizes and levels of accuracy for the control design and closed-loop simulations. The optical modeling code BeamWarrior was developed by ESO and Astrium GmbH, Germany) especially for integrated modeling and interfering with a structural model. Within BeamWarrior displacements and deformations can be applied in an arbitrary coordinate system, and hence also in the global coordinates of the FE model avoiding error prone transformations. In addition to this, a sparse state space model object was developed for Matlab to gain in computational efficiency and reduced memory requirements due to the sparsity pattern of both the structural models and the control architecture. As one result these tools allow building an integrated model in order to reliably simulate interactions, cross-coupling effects, system responses, and to evaluate global performance. In order to evaluate disturbance effects on the optical performance in openloop more efficiently, an optical evaluation toolbox was built in the FE software ANSYS which performs Zernike decomposition and best-fit computation of the deformations directly in the FE analysis.

The NSF ITR Project: Framework for the National Virtual Observatory

NASA Astrophysics Data System (ADS)

Szalay, A. S.; Williams, R. D.; NVO Collaboration

2002-05-01

Technological advances in telescope and instrument design during the last ten years, coupled with the exponential increase in computer and communications capability, have caused a dramatic and irreversible change in the character of astronomical research. Large-scale surveys of the sky from space and ground are being initiated at wavelengths from radio to x-ray, thereby generating vast amounts of high quality irreplaceable data. The potential for scientific discovery afforded by these new surveys is enormous. Entirely new and unexpected scientific results of major significance will emerge from the combined use of the resulting datasets, science that would not be possible from such sets used singly. However, their large size and complexity require tools and structures to discover the complex phenomena encoded within them. We plan to build the NVO framework both through coordinating diverse efforts already in existence and providing a focus for the development of capabilities that do not yet exist. The NVO we envisage will act as an enabling and coordinating entity to foster the development of further tools, protocols, and collaborations necessary to realize the full scientific potential of large astronomical datasets in the coming decade. The NVO must be able to change and respond to the rapidly evolving world of IT technology. In spite of its underlying complex software, the NVO should be no harder to use for the average astronomer, than today's brick-and-mortar observatories and telescopes. Development of these capabilities will require close interaction and collaboration with the information technology community and other disciplines facing similar challenges. We need to ensure that the tools that we need exist or are built, but we do not duplicate efforts, and rely on relevant experience of others.

Enhancing response coordination through the assessment of response network structural dynamics

PubMed Central

Jalili, Mahdi; Choi, Soo-Mi

2018-01-01

Preparing for intensifying threats of emergencies in unexpected, dangerous, and serious natural or man-made events, and consequent management of the situation, is highly demanding in terms of coordinating the personnel and resources to support human lives and the environment. This necessitates prompt action to manage the uncertainties and risks imposed by such extreme events, which requires collaborative operation among different stakeholders (i.e., the personnel from both the state and local communities). This research aims to find a way to enhance the coordination of multi-organizational response operations. To do so, this manuscript investigates the role of participants in the formed coordination response network and also the emergence and temporal dynamics of the network. By analyzing an inter-personal response coordination operation to an extreme bushfire event, the networks’ and participants’ structural change is evaluated during the evolution of the operation network over four time durations. The results reveal that the coordination response network becomes more decentralized over time due to the high volume of communication required to exchange information. New emerging communication structures often do not fit the developed plans, which stress the need for coordination by feedback in addition to by plan. In addition, we find that the participant’s brokering role in the response operation network identifies a formal and informal coordination role. This is useful for comparison of network structures to examine whether what really happens during response operations complies with the initial policy. PMID:29447192

Enhancing response coordination through the assessment of response network structural dynamics.

PubMed

Abbasi, Alireza; Sadeghi-Niaraki, Abolghasem; Jalili, Mahdi; Choi, Soo-Mi

2018-01-01

Preparing for intensifying threats of emergencies in unexpected, dangerous, and serious natural or man-made events, and consequent management of the situation, is highly demanding in terms of coordinating the personnel and resources to support human lives and the environment. This necessitates prompt action to manage the uncertainties and risks imposed by such extreme events, which requires collaborative operation among different stakeholders (i.e., the personnel from both the state and local communities). This research aims to find a way to enhance the coordination of multi-organizational response operations. To do so, this manuscript investigates the role of participants in the formed coordination response network and also the emergence and temporal dynamics of the network. By analyzing an inter-personal response coordination operation to an extreme bushfire event, the networks' and participants' structural change is evaluated during the evolution of the operation network over four time durations. The results reveal that the coordination response network becomes more decentralized over time due to the high volume of communication required to exchange information. New emerging communication structures often do not fit the developed plans, which stress the need for coordination by feedback in addition to by plan. In addition, we find that the participant's brokering role in the response operation network identifies a formal and informal coordination role. This is useful for comparison of network structures to examine whether what really happens during response operations complies with the initial policy.

Comparison of methods for developing the dynamics of rigid-body systems

NASA Technical Reports Server (NTRS)

Ju, M. S.; Mansour, J. M.

1989-01-01

Several approaches for developing the equations of motion for a three-degree-of-freedom PUMA robot were compared on the basis of computational efficiency (i.e., the number of additions, subtractions, multiplications, and divisions). Of particular interest was the investigation of the use of computer algebra as a tool for developing the equations of motion. Three approaches were implemented algebraically: Lagrange's method, Kane's method, and Wittenburg's method. Each formulation was developed in absolute and relative coordinates. These six cases were compared to each other and to a recursive numerical formulation. The results showed that all of the formulations implemented algebraically required fewer calculations than the recursive numerical algorithm. The algebraic formulations required fewer calculations in absolute coordinates than in relative coordinates. Each of the algebraic formulations could be simplified, using patterns from Kane's method, to yield the same number of calculations in a given coordinate system.

Considerations and Architectures for Inter-Satellite Communications in Distributed Spacecraft Systems

NASA Technical Reports Server (NTRS)

Edwards, Bernard; Horne, William; Israel, David; Kwadrat, Carl; Bauer, Frank H. (Technical Monitor)

2001-01-01

This paper will identify the important characteristics and requirements necessary for inter-satellite communications in distributed spacecraft systems and present analysis results focusing on architectural and protocol comparisons. Emerging spacecraft systems plan to deploy multiple satellites in various "distributed" configurations ranging from close proximity formation flying to widely separated constellations. Distributed spacecraft configurations provide advantages for science exploration and operations since many activities useful for missions may be better served by distributing them between spacecraft. For example, many scientific observations can be enhanced through spatially separated platforms, such as for deep space interferometry. operating multiple distributed spacecraft as a mission requires coordination that may be best provided through inter-satellite communications. For example, several future distributed spacecraft systems envision autonomous operations requiring relative navigational calculations and coordinated attitude and position corrections. To conduct these operations, data must be exchanged between spacecraft. Direct cross-links between satellites provides an efficient and practical method for transferring data and commands. Unlike existing "bent-pipe" relay networks supporting space missions, no standard or widely-used method exists for cross-link communications. Consequently, to support these future missions, the characteristics necessary for inter-satellite communications need to be examined. At first glance, all of the missions look extremely different. Some missions call for tens to hundreds of nano-satellites in constant communications in close proximity to each other. Other missions call for a handful of satellites communicating very slowly over thousands to hundreds of thousands of kilometers. The paper will first classify distributed spacecraft missions to help guide the evaluation and definition of cross-link architectures and approaches. Based on this general classification, the paper will examine general physical layer parameters, such as frequency bands and data rates, necessary to support the missions. The paper will also identify classes of communication architectures that may be employed, ranging from fully distributed to centralized topologies. Numerous factors, such as number of spacecraft, must be evaluated when attempting to pick a communications architecture. Also important is the stability of the formation from a communications standpoint. For example, do all of the spacecraft require equal bandwidth and are spacecraft allowed to enter and leave a formation? The type of science mission being attempted may also heavily influence the communications architecture. In addition, the paper will assess various parameters and characteristics typically associated with the data link layer. The paper will analyze the performance of various multiple access techniques given the operational scenario, requirements, and communication topologies envisioned for missions. This assessment will also include a survey of existing standards and their applicability for distributed spacecraft systems. An important consideration includes the interoperability of the lower layers (physical and data link) examined in this paper with the higher layer protocols(network) envisioned for future space internetworking. Finally, the paper will define a suggested path, including preliminary recommendations, for defining and developing a standard for intersatellite communications based on the classes of distributed spacecraft missions and analysis results.

Gyro-gauge-independent formulation of the guiding-center reduction to arbitrary order in the Larmor radius

NASA Astrophysics Data System (ADS)

de Guillebon, L.; Vittot, M.

2013-10-01

Guiding-center reduction is studied using gyro-gauge-independent coordinates. The Lagrangian 1-form of charged particle dynamics is Lie transformed without introducing a gyro-gauge, but using directly the unit vector of the component of the velocity perpendicular to the magnetic field as the coordinate corresponding to Larmor gyration. The reduction is shown to provide a maximal reduction for the Lagrangian and to work for all orders in the Larmor radius, following exactly the same procedure as when working with the standard gauge-dependent coordinate. The gauge-dependence is removed from the coordinate system by using a constrained variable for the gyro-angle. The closed 1-form dθ is replaced by a more general non-closed 1-form, which is equal to dθ in the gauge-dependent case. The gauge vector is replaced by a more general connection in the definition of the gradient, which behaves as a covariant derivative, in perfect agreement with the circle-bundle picture. This explains some results of previous works, whose gauge-independent expressions did not correspond to gauge fixing but did indeed correspond to connection fixing. In addition, some general results are obtained for the guiding-center reduction. The expansion is polynomial in the cotangent of the pitch-angle as an effect of the structure of the Lagrangian, preserved by Lie derivatives. The induction for the reduction is shown to rely on the inversion of a matrix, which is the same for all orders higher than three. It is inverted and explicit induction relations are obtained to go to an arbitrary order in the perturbation expansion. The Hamiltonian and symplectic representations of the guiding-center reduction are recovered, but conditions for the symplectic representation at each order are emphasized.

Metals in proteins: correlation between the metal-ion type, coordination number and the amino-acid residues involved in the coordination.

PubMed

Dokmanić, Ivan; Sikić, Mile; Tomić, Sanja

2008-03-01

Metal ions are constituents of many metalloproteins, in which they have either catalytic (metalloenzymes) or structural functions. In this work, the characteristics of various metals were studied (Cu, Zn, Mg, Mn, Fe, Co, Ni, Cd and Ca in proteins with known crystal structure) as well as the specificity of their environments. The analysis was performed on two data sets: the set of protein structures in the Protein Data Bank (PDB) determined with resolution <1.5 A and the set of nonredundant protein structures from the PDB. The former was used to determine the distances between each metal ion and its electron donors and the latter was used to assess the preferred coordination numbers and common combinations of amino-acid residues in the neighbourhood of each metal. Although the metal ions considered predominantly had a valence of two, their preferred coordination number and the type of amino-acid residues that participate in the coordination differed significantly from one metal ion to the next. This study concentrates on finding the specificities of a metal-ion environment, namely the distribution of coordination numbers and the amino-acid residue types that frequently take part in coordination. Furthermore, the correlation between the coordination number and the occurrence of certain amino-acid residues (quartets and triplets) in a metal-ion coordination sphere was analysed. The results obtained are of particular value for the identification and modelling of metal-binding sites in protein structures derived by homology modelling. Knowledge of the geometry and characteristics of the metal-binding sites in metalloproteins of known function can help to more closely determine the biological activity of proteins of unknown function and to aid in design of proteins with specific affinity for certain metals.

FY 2007 Progress Report for Upper Columbia United Tribes' Regional Coordination.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Michel, D.R.

2008-12-15

This report is a summary of activities conducted over the fiscal year 2007 contract period to fulfill requirements to coordinate Upper Columbia United Tribes (UCUT) interests within the Columbia River Basin. This coordination was specific to the implementation of portions of the Integrated Fish and Wildlife Program within the purview of the Northwest Power and Conservation Council and Bonneville Power Administration.

Care Coordination and Transitions of Care.

PubMed

Choi, Youngjee

2017-11-01

Care coordination and effective transitions of care are essential for high-quality care in cancer survivors. Aspects of care that require coordination include cancer surveillance, managing the effects of cancer and its treatment, and preventive care, including screening for new cancers, with the clinician responsible for each aspect of care clearly defined. There are many barriers to transitioning and coordinating care across cancer specialists and primary care physicians; possible solutions include survivorship care plans and certain care models. Improving these areas, along with survivorship care training and education, may lead to more effective care coordination and transitions in the future. Copyright © 2017 Elsevier Inc. All rights reserved.

Robust recognition of handwritten numerals based on dual cooperative network

NASA Technical Reports Server (NTRS)

Lee, Sukhan; Choi, Yeongwoo

1992-01-01

An approach to robust recognition of handwritten numerals using two operating parallel networks is presented. The first network uses inputs in Cartesian coordinates, and the second network uses the same inputs transformed into polar coordinates. How the proposed approach realizes the robustness to local and global variations of input numerals by handling inputs both in Cartesian coordinates and in its transformed Polar coordinates is described. The required network structures and its learning scheme are discussed. Experimental results show that by tracking only a small number of distinctive features for each teaching numeral in each coordinate, the proposed system can provide robust recognition of handwritten numerals.

Ultra-Compact Transputer-Based Controller for High-Level, Multi-Axis Coordination

NASA Technical Reports Server (NTRS)

Zenowich, Brian; Crowell, Adam; Townsend, William T.

2013-01-01

The design of machines that rely on arrays of servomotors such as robotic arms, orbital platforms, and combinations of both, imposes a heavy computational burden to coordinate their actions to perform coherent tasks. For example, the robotic equivalent of a person tracing a straight line in space requires enormously complex kinematics calculations, and complexity increases with the number of servo nodes. A new high-level architecture for coordinated servo-machine control enables a practical, distributed transputer alternative to conventional central processor electronics. The solution is inherently scalable, dramatically reduces bulkiness and number of conductor runs throughout the machine, requires only a fraction of the power, and is designed for cooling in a vacuum.

Adapting Project Management Practices to Research-Based Projects

NASA Technical Reports Server (NTRS)

Bahr, P.; Baker, T.; Corbin, B.; Keith, L.; Loerch, L.; Mullenax, C.; Myers, R.; Rhodes, B.; Skytland, N.

2007-01-01

From dealing with the inherent uncertainties in outcomes of scientific research to the lack of applicability of current NASA Procedural Requirements guidance documentation, research-based projects present challenges that require unique application of classical project management techniques. If additionally challenged by the creation of a new program transitioning from basic to applied research in a technical environment often unfamiliar with the cost and schedule constraints addressed by project management practices, such projects can find themselves struggling throughout their life cycles. Finally, supplying deliverables to a prime vehicle customer, also in the formative stage, adds further complexity to the development and management of research-based projects. The Biomedical Research and Countermeasures Projects Branch at NASA Johnson Space Center encompasses several diverse applied research-based or research-enabling projects within the newly-formed Human Research Program. This presentation will provide a brief overview of the organizational structure and environment in which these projects operate and how the projects coordinate to address and manage technical requirements. We will identify several of the challenges (cost, technical, schedule, and personnel) encountered by projects across the Branch, present case reports of actions taken and techniques implemented to deal with these challenges, and then close the session with an open forum discussion of remaining challenges and potential mitigations.

Cohesion and coordination effects on transition metal surface energies

NASA Astrophysics Data System (ADS)

Ruvireta, Judit; Vega, Lorena; Viñes, Francesc

2017-10-01

Here we explore the accuracy of Stefan equation and broken-bond model semiempirical approaches to obtain surface energies on transition metals. Cohesive factors are accounted for either via the vaporization enthalpies, as proposed in Stefan equation, or via cohesive energies, as employed in the broken-bond model. Coordination effects are considered including the saturation degree, as suggested in Stefan equation, employing Coordination Numbers (CN), or as the ratio of broken bonds, according to the bond-cutting model, considering as well the square root dependency of the bond strength on CN. Further, generalized coordination numbers CN bar are contemplated as well, exploring a total number of 12 semiempirical formulations on the three most densely packed surfaces of 3d, 4d, and 5d Transition Metals (TMs) displaying face-centered cubic (fcc), body-centered cubic (bcc), or hexagonal close-packed (hcp) crystallographic structures. Estimates are compared to available experimental surface energies obtained extrapolated to zero temperature. Results reveal that Stefan formula cohesive and coordination dependencies are only qualitative suited, but unadvised for quantitative discussion, as surface energies are highly overestimated, favoring in addition the stability of under-coordinated surfaces. Broken-bond cohesion and coordination dependencies are a suited basis for quantitative comparison, where square-root dependencies on CN to account for bond weakening are sensibly worse. An analysis using Wulff shaped averaged surface energies suggests the employment of broken-bond model using CN to gain surface energies for TMs, likely applicable to other metals.

Dilemma zone protection and signal coordination at closely-spaced high-speed intersections : final report, November 2001.

DOT National Transportation Integrated Search

2001-11-01

A feasibility study of dilemma zone problems, performed by collecting and analyzing traffic flow data at a high-speed signalized intersection, showed that the maximum green extension or cutback needed to get a vehicle out of the dilemma zone is gener...

The Next Decade in Higher Education: Obvious Problems and Possible Solutions.

ERIC Educational Resources Information Center

Cheit, Earl F.

Problems confronting higher education are considered from the perspective of state coordinating agencies. Ten obvious problems are as follows: adjusting to new enrollment patterns; attempting to close the cost-income gap; expenditures increasing more rapidly than income; supporting the capacity for research and advanced study; meeting new…

36 CFR 242.19 - Special actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., or temporary changes for subsistence uses on public lands. (g) You may not take fish and wildlife in... coordination with the submitter. In general, changes to Customary and Traditional Use Determinations will only... lands, or close or restrict non-subsistence uses of fish and wildlife on public lands, if necessary to...

Conjunction Functions

ERIC Educational Resources Information Center

Riddle, Bob

2007-01-01

This spring, as the school year starts to wind down, there will be many opportunities for students to observe bright planets and to wrap up the year with some great conjunctions and close occultation with the Moon, planets, bright stars, and star clusters). These observations can be coordinated with student observations of the Moon's phase cycle…

Dilemma zone protection and signal coordination at closely-spaced high-speed intersections : executive summary, November 2001.

DOT National Transportation Integrated Search

2001-11-01

A feasibility study of dilemma zone problems, performed by collecting and analyzing traffic flow data at a high-speed signalized intersection, showed that the maximum green extension or cutback needed to get a vehicle out of the dilemma zone is gener...

Taken for Granted: Why Curriculum Content Is Like Oxygen

ERIC Educational Resources Information Center

Gosse, Carolyn; Hansel, Lisa

2014-01-01

For educators, the content of the curriculum really is like oxygen: it is the necessary precondition for improving schools, closing the achievement gap, engaging parents, and preparing teachers. However, when educators take the content of the curriculum for granted, they lose opportunities to coordinate and collaborate. Good curriculum instruction…

76 FR 61722 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-05

... Institute Special Emphasis Panel, Data Coordinating Center for the Cardiovascular Cell Therapy Research... Special Emphasis Panel, Regional Clinical Center for the Cardiovascular Cell Therapy Research Network... Capture Agents for Cardiovascular Research. Date: October 24, 2011. Time: 1 p.m. to 3 p.m. Agenda: To...

40 CFR 300.215 - Title III local emergency response plans.

Code of Federal Regulations, 2014 CFR

2014-07-01

... should be closely coordinated with applicable federal ACPs and state emergency response plans. (b... POLLUTION CONTINGENCY PLAN Planning and Preparedness § 300.215 Title III local emergency response plans... are codified at 40 CFR part 355. (a) Each LEPC is to prepare an emergency response plan in accordance...

40 CFR 300.215 - Title III local emergency response plans.

Code of Federal Regulations, 2010 CFR

2010-07-01

... should be closely coordinated with applicable federal ACPs and state emergency response plans. (b... POLLUTION CONTINGENCY PLAN Planning and Preparedness § 300.215 Title III local emergency response plans... are codified at 40 CFR part 355. (a) Each LEPC is to prepare an emergency response plan in accordance...

40 CFR 300.215 - Title III local emergency response plans.

Code of Federal Regulations, 2011 CFR

2011-07-01

... should be closely coordinated with applicable federal ACPs and state emergency response plans. (b... POLLUTION CONTINGENCY PLAN Planning and Preparedness § 300.215 Title III local emergency response plans... are codified at 40 CFR part 355. (a) Each LEPC is to prepare an emergency response plan in accordance...

40 CFR 300.215 - Title III local emergency response plans.

Code of Federal Regulations, 2013 CFR

2013-07-01

... should be closely coordinated with applicable federal ACPs and state emergency response plans. (b... POLLUTION CONTINGENCY PLAN Planning and Preparedness § 300.215 Title III local emergency response plans... are codified at 40 CFR part 355. (a) Each LEPC is to prepare an emergency response plan in accordance...

40 CFR 300.215 - Title III local emergency response plans.

Code of Federal Regulations, 2012 CFR

2012-07-01

... should be closely coordinated with applicable federal ACPs and state emergency response plans. (b... POLLUTION CONTINGENCY PLAN Planning and Preparedness § 300.215 Title III local emergency response plans... are codified at 40 CFR part 355. (a) Each LEPC is to prepare an emergency response plan in accordance...

77 FR 55265 - Environmental Impact Statement for the Northeast Corridor Between Washington, DC, New York, NY...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-07

... the Northeast Corridor Between Washington, DC, New York, NY, and Boston, MA AGENCY: Federal Railroad... ). SUPPLEMENTARY INFORMATION: FRA is leading the planning and environmental evaluation of the Northeast Corridor (NEC) in close coordination with the involved states, Northeast Corridor Infrastructure and Operations...

Development of Cooperative Planning for Technical-Vocational Programs.

ERIC Educational Resources Information Center

Cisco Junior Coll., TX.

During the past decade vocational-technical education in Texas has grown so rapidly that now attention must be given to enrollments, employment projections, and more efficient utilization of the limited resources available. Cisco and Ranger Junior Colleges serve essentially the same population and a plan for close cooperation and coordination is…

Office of Economic Adjustment | U.S. Department of Defense

Science.gov Websites

Reuse Compatible Use Defense Contractor Transitions Federal Assistance Coordination Mission Change contractor or manufacturer is making cuts or closing. Explore BRAC Icon Base Realignment and Closure A contact information. What We Do Base Closure Base Realignment Base Reuse Compatible Use Defense Contractor

A Molecular Titration System Coordinates Ribosomal Protein Gene Transcription with Ribosomal RNA Synthesis.

PubMed

Albert, Benjamin; Knight, Britta; Merwin, Jason; Martin, Victoria; Ottoz, Diana; Gloor, Yvonne; Bruzzone, Maria Jessica; Rudner, Adam; Shore, David

2016-11-17

Cell growth potential is determined by the rate of ribosome biogenesis, a complex process that requires massive and coordinated transcriptional output. In the yeast Saccharomyces cerevisiae, ribosome biogenesis is highly regulated at the transcriptional level. Although evidence for a system that coordinates ribosomal RNA (rRNA) and ribosomal protein gene (RPG) transcription has been described, the molecular mechanisms remain poorly understood. Here we show that an interaction between the RPG transcriptional activator Ifh1 and the rRNA processing factor Utp22 serves to coordinate RPG transcription with that of rRNA. We demonstrate that Ifh1 is rapidly released from RPG promoters by a Utp22-independent mechanism following growth inhibition, but that its long-term dissociation requires Utp22. We present evidence that RNA polymerase I activity inhibits the ability of Utp22 to titrate Ifh1 from RPG promoters and propose that a dynamic Ifh1-Utp22 interaction fine-tunes RPG expression to coordinate RPG and rRNA transcription. Copyright © 2016 Elsevier Inc. All rights reserved.

Hyperfine coupling constants on inner-sphere water molecules of Gd(III)-based MRI contrast agents.

PubMed

Esteban-Gómez, David; de Blas, Andrés; Rodríguez-Blas, Teresa; Helm, Lothar; Platas-Iglesias, Carlos

2012-11-12

Herein we present a theoretical investigation of the hyperfine coupling constants (HFCCs) on the inner-sphere water molecules of [Gd(H(2)O)(8)](3+) and different Gd(III)-based magnetic resonance imaging contrast agents such as [Gd(DOTA)(H(2)O)](-), [Gd(DTPA)(H(2)O)](2-), [Gd(DTPA-BMA)(H(2)O)] and [Gd(HP-DO3A)(H(2)O)]. DFT calculations performed on the [Gd(H(2)O)(8)](3+) model system show that both hybrid-GGA functionals (BH&HLYP, B3PW91 and PBE1PBE) and the hybrid meta-GGA functional TPSSh provide (17)O HFCCs in close agreement with the experimental data. The use of all-electron relativistic approaches based on the DKH2 approximation and the use of relativistic effective core potentials (RECP) provide results of essentially the same quality. The accurate calculation of HFCCs on the [Gd(DOTA)(H(2)O)](-), [Gd(DTPA)(H(2)O)](2-), [Gd(DTPA-BMA)(H(2)O)] and [Gd(HP-DO3A)(H(2)O)] complexes requires an adequate description of solvent effects. This was achieved by using a mixed cluster/continuum approach that includes explicitly two second-sphere water molecules. The calculated isotropic (17)O HFCCs (A(iso)) fall within the range 0.40-0.56 MHz, and show deviations from the corresponding experimental values typically lower than 0.05 MHz. The A(iso) values are significantly affected by the distance between the oxygen atom of the coordinated water molecule and the Gd(III) ion, as well as by the orientation of the water molecule plane with respect to the Gd-O vector. (1)H HFCCs of coordinated water molecules and (17)O HFCCs of second-sphere water molecules take values close to zero. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

State-Based Implicit Coordination and Applications

NASA Technical Reports Server (NTRS)

Narkawicz, Anthony J.; Munoz, Cesar A.

2011-01-01

In air traffic management, pairwise coordination is the ability to achieve separation requirements when conflicting aircraft simultaneously maneuver to solve a conflict. Resolution algorithms are implicitly coordinated if they provide coordinated resolution maneuvers to conflicting aircraft when only surveillance data, e.g., position and velocity vectors, is periodically broadcast by the aircraft. This paper proposes an abstract framework for reasoning about state-based implicit coordination. The framework consists of a formalized mathematical development that enables and simplifies the design and verification of implicitly coordinated state-based resolution algorithms. The use of the framework is illustrated with several examples of algorithms and formal proofs of their coordination properties. The work presented here supports the safety case for a distributed self-separation air traffic management concept where different aircraft may use different conflict resolution algorithms and be assured that separation will be maintained.

47 CFR 22.169 - International coordination of channel assignments.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false International coordination of channel assignments. 22.169 Section 22.169 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES PUBLIC MOBILE SERVICES Licensing Requirements and Procedures Applications and...

A Copay Foundation Assistance Support Program for Patients Receiving Intravenous Cancer Therapy

PubMed Central

Rajurkar, Swapnil P.; Presant, Cary A.; Bosserman, Linda D.; McNatt, Wendy J.

2011-01-01

Purpose: With the advent of newer cancer therapies (eg, biologic and cytotoxic), treatment is becoming increasingly expensive for patients with cancer. Patients enrolled in Medicare and commercial insurance plans often have large copay requirements with each treatment cycle. Often, these patients undergo significant financial hardship, and some patients decline treatment. We have developed a support program that works closely with all copay assistance foundations to secure financial assistance to facilitate appropriate treatment. Methods: In September, 2008 we initiated a coordinated program with various copay assistance foundations, including Healthwell, Cancer Care, Patient Access, Chronic Disease Fund, Beckstrand Cancer, Lilly Cares and the Leukemia and Lymphoma Society. Patients requesting assistance with chemotherapy copay were enrolled in this program. Information about income level, chemotherapy regimens, and associated copay was given to these foundations, who then determined the amount of monetary assistance. Results: Since the initiation of this program, of 201 patients who began receiving chemotherapy, 25 (12.4%) requested assistance with this program for either intravenous or oral treatments. The current results of time delays for foundation decision, success rates and administrative costs to secure funding will be presented at the time of the poster presentation. Conclusion: Copay for chemotherapy drugs is a financial hardship for a significant number of patients. Coordinated resources must be provided and reimbursed to facilitate appropriate and sustainable cancer care. This program is a successful model for other centers to adopt. PMID:21731517

Drainage area data for Alabama streams

USGS Publications Warehouse

Stallings, J.S.; Peirce, L.B.

1957-01-01

The drainage area of a river basin is an important parameter in many engineering equations used for hydrologic design. It is not a parameter, however, that always requires precise measurement. Factors in the hydrologic cycle such as rainfall, runoff, transpiration, and infiltration cannot be measured nearly as closely as drainage area. Largely for this reason, drainage areas are often measured to varying degrees of precision depending upon the immediate need, with little thought to some other use or some other user of the figure obtained. It can readily be appreciated that this practice, continued for long by many different agencies, will result in a heterogeneous collection of drainage area figures, often discordant and of an accuracy unknown to any but those who computed them. Figures of drainage area published by various Federal agencies are frequently discrepant or contradictory, giving rise to confusion in the use of drainage area data. Seeking to better this situation, the Federal Inter-Agency River Basin Committee (FIARBC) in November 1951 published its Bulletin No. 4, Inter-Agency Coordination of Drainage Area Data. That Bulletin recommended procedures to be followed by the interested Federal agencies “for coordinating drainage area data in the interest of promoting uniformity, reducing confusion and contradiction of published figures, and improving the ready availability of drainage area data pertaining to drainage basins of the United States and its possessions.”

Space Weather Modeling at the Community Coordinated Modeling Center

NASA Astrophysics Data System (ADS)

Hesse, M.; Falasca, A.; Johnson, J.; Keller, K.; Kuznetsova, M.; Rastaetter, L.

2003-04-01

The Community Coordinated Modeling Center (CCMC) is a multi-agency partnership aimed at the creation of next generation space weather models. The goal of the CCMC is to support the research and developmental work necessary to substantially increase the present-day modeling capability for space weather purposes, and to provide models for transition to the rapid prototyping centers at the space weather forecast centers. This goal requires close collaborations with and substantial involvement of the research community. The physical regions to be addressed by CCMC-related activities range from the solar atmosphere to the Earth's upper atmosphere. The CCMC is an integral part of NASA's Living With a Star (LWS) initiative, of the National Space Weather Program Implementation Plan, and of the Department of Defense Space Weather Transition Plan. CCMC includes a facility at NASA Goddard Space Flight Center, as well as distributed computing facilities provided by the US Air Force. CCMC also provides, to the research community, access to state-of-the-art space research models. In this paper we will provide updates on CCMC status, on current plans, research and development accomplishments and goals, and on the model testing and validation process undertaken as part of the CCMC mandate. We will demonstrate the capabilities of models resident at CCMC via the analysis of a geomagnetic storm, driven by a shock in the solar wind.

Coordinating activities between NOAA and other agencies.

PubMed

Fritz, A T; Buchman, M F

1997-11-01

The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and the National Oil and Hazardous Substances Pollution Contingency Plan (NCP) mandate protection of public health, welfare, and the environment at Superfund hazardous waste sites. The NCP requires lead response agenciesto integrate baseline risk assessments into the remedial process that "assess threats to the environment." EPA policy statements direct regional offices to perform thorough, consistent ecological risk assessments, and stress the importance of coordination and technical consultation with the natural resource trustees. As a Federal natural trustee, the National Oceanic and Atmospheric Administration's (NOAA) role and responsibilities within the CERCLA process also are defined and mandated by Federal law. NOAA is responsible for identifying sites in the coastal zone that may affect natural resources, evaluating injury to trust resources, and providing technical advice on assessments and remedial and restoration alternatives. Statutes require lead cleanup agencies and trustee agencies to notify and coordinate with each other during CERCLA response. Over the past ten years, NOAA has gained valuable experience and technical expertise in environmental assessments and in evaluating contaminated aquatic environments. NOAA fulfills its responsibilities through an effective network of Coastal Resource Coordinators (CRCs) who can rapidly respond to local technical requirements and priorities, and coordinate effectively with technical and trustee representatives. In addition to CRCs, an interdisciplinary support group provides technical expertise in the scientific disciplines required to respond to the needs of regional activities. NOAA provides CRCs to coastal EPA regional offices for technical support, and to act as liaisons with Federal and state natural resource trustee agencies. The CRCs help EPA and other lead response agencies identify and assess risks to coastal resources from hazardous waste sites and to develop cost-effective strategies to minimize those risks. Notification of trustees of potential natural resource injuries and coordination of subsequent investigations helps Federal and state trustees to carry out their responsibilities effectively. Trustees' early involvement in the scoping of ecological risk assessments ensures that assessments and the entire remedial process adequately evaluate the risk to trust resources. Coordination throughout the process makes it easier to develop cost-effective and protective remedies that enhance the recovery of natural resources. Examples of NOAA's successful coordination and cooperative ecological risk assessments will be presented in brief case studies for both EPA and Department of Defense (DOD) lead sites.

Epistemic companions: shared reality development in close relationships.

PubMed

Rossignac-Milon, Maya; Higgins, E Tory

2018-01-11

We propose a framework outlining the development of shared reality in close relationships. In this framework, we attempt to integrate disparate close relationship phenomena under the conceptual umbrella of shared reality. We argue that jointly satisfying epistemic needs-making sense of the world together-plays an important but under-appreciated role in establishing and maintaining close relationships. Specifically, we propose that dyads progress through four cumulative phases in which new forms of shared reality emerge. Relationships are often initiated when people discover Shared Feelings, which then facilitate the co-construction of dyad-specific Shared Practices. Partners then form an interdependent web of Shared Coordination and ultimately develop a Shared Identity. Each emergent form of shared reality continues to evolve throughout subsequent phases, and, if neglected, can engender relationship dissolution. Copyright © 2018 Elsevier Ltd. All rights reserved.

Role of the Controller in an Integrated Pilot-Controller Study for Parallel Approaches

NASA Technical Reports Server (NTRS)

Verma, Savvy; Kozon, Thomas; Ballinger, Debbi; Lozito, Sandra; Subramanian, Shobana

2011-01-01

Closely spaced parallel runway operations have been found to increase capacity within the National Airspace System but poor visibility conditions reduce the use of these operations [1]. Previous research examined the concepts and procedures related to parallel runways [2][4][5]. However, there has been no investigation of the procedures associated with the strategic and tactical pairing of aircraft for these operations. This study developed and examined the pilot s and controller s procedures and information requirements for creating aircraft pairs for closely spaced parallel runway operations. The goal was to achieve aircraft pairing with a temporal separation of 15s (+/- 10s error) at a coupling point that was 12 nmi from the runway threshold. In this paper, the role of the controller, as examined in an integrated study of controllers and pilots, is presented. The controllers utilized a pairing scheduler and new pairing interfaces to help create and maintain aircraft pairs, in a high-fidelity, human-in-the loop simulation experiment. Results show that the controllers worked as a team to achieve pairing between aircraft and the level of inter-controller coordination increased when the aircraft in the pair belonged to different sectors. Controller feedback did not reveal over reliance on the automation nor complacency with the pairing automation or pairing procedures.

Revisiting the Darmois and Lichnerowicz junction conditions

NASA Astrophysics Data System (ADS)

Lake, Kayll

2017-10-01

What have become known as the "Darmois" and "Lichnerowicz" junction conditions are often stated to be equivalent, "essentially" equivalent, in a "sense" equivalent, and so on. One even sees not infrequent reference to the "Darmois-Lichnerowicz" conditions. Whereas the equivalence of these conditions is manifest in Gaussian-normal coordinates, a fact that has been known for close to a century, this equivalence does not extend to a loose definition of "admissible" coordinates (coordinates in which the metric and its first order derivatives are continuous). We show this here by way of a simple, but physically relevant, example. In general, a loose definition of the "Lichnerowicz" conditions gives additional restrictions, some of which simply amount to a convenient choice of gauge, and some of which amount to real physical restrictions, away from strict "admissible" coordinates. The situation was totally confused by a very influential, and now frequently misquoted, paper by Bonnor and Vickers, that erroneously claimed a proof of the equivalence of the "Darmois" and "Lichnerowicz" conditions within this loose definition of "admissible" coordinates. A correct proof, based on a strict definition of "admissible" coordinates, was given years previous by Israel. It is that proof, generally unrecognized, that we must refer to. Attention here is given to a clarification of the subject, and to the history of the subject, which, it turns out, is rather fascinating in itself.

Shuttle program. MCC Level C formulation requirements: Entry guidance and entry autopilot

NASA Technical Reports Server (NTRS)

Harpold, J. C.; Hill, O.

1980-01-01

A set of preliminary entry guidance and autopilot software formulations is presented for use in the Mission Control Center (MCC) entry processor. These software formulations meet all level B requirements. Revision 2 incorporates the modifications required to functionally simulate optimal TAEM targeting capability (OTT). Implementation of this logic in the MCC must be coordinated with flight software OTT implementation and MCC TAEM guidance OTT. The entry guidance logic is based on the Orbiter avionics entry guidance software. This MCC requirements document contains a definition of coordinate systems, a list of parameter definitions for the software formulations, a description of the entry guidance detailed formulation requirements, a description of the detailed autopilot formulation requirements, a description of the targeting routine, and a set of formulation flow charts.

Computation of Thin-Walled Prismatic Shells

NASA Technical Reports Server (NTRS)

Vlasov, V. Z.

1949-01-01

We consider a prismatic shell consisting of a finite number of narrow rectangular plates and having in the cross-section a finite number of closed contours (fig. 1(a)). We shall assume that the rectangular plates composing the shell are rigidly joined so that there is no motion of any kind of one plate relative to the others meeting at a given connecting line. The position of a point on the middle prismatic surface is considered to be defined by the coordinate z, the distance to a certain initial cross-section z = O, end the coordinate s determining its position on the contour of the cross-section.

Referential calls coordinate multi-species mobbing in a forest bird community.

PubMed

Suzuki, Toshitaka N

2016-01-01

Japanese great tits ( Parus minor ) use a sophisticated system of anti-predator communication when defending their offspring: they produce different mobbing calls for different nest predators (snake versus non-snake predators) and thereby convey this information to conspecifics (i.e. functionally referential call system). The present playback experiments revealed that these calls also serve to coordinate multi-species mobbing at nests; snake-specific mobbing calls attracted heterospecific individuals close to the sound source and elicited snake-searching behaviour, whereas non-snake mobbing calls attracted these birds at a distance. This study demonstrates for the first time that referential mobbing calls trigger different formations of multi-species mobbing parties.

The effect of varying linker length on ion-transport properties in polymeric ionic liquids

NASA Astrophysics Data System (ADS)

Keith, Jordan; Mogurampelly, Santosh; Wheatle, Bill; Ganesan, Venkat

We report results of atomistic molecular dynamics simulations on polymerized 1-butyl-3-(n-alkyl)imidazolium ionic liquids with PF6- counterions. Consistent with experimental observations, we observe that the mobility of the PF6- ions increases with increasing n-alkyl linker length. Analysis of our results suggests that the motion of PF6- ions is driven by intermolecular ion hopping between chains, which in turn is influenced by ion-pair coordination numbers and intermolecular ionic separation distances. With increasing linker length, we observe 1) the anions coordinating less closely with cations and 2) intermolecular hopping distances decreasing.

CTS (Hermes): United States experiments and operations summary

NASA Technical Reports Server (NTRS)

Donoughe, P. L.; Hunczak, H. R.

1977-01-01

The Communications Technology Satellite, launched in January 1976 and embodying the highest power transmitter in a communications satellite, was considered. As a joint program between the U.S. and Canada, close coordination of the two countries was necessitated since the management and control of experiments were done in real time. Criteria used by NASA for acceptance of the United States experiments are noted and acceptance procedures are discussed. The category for each accepted experiment is given. The modus operandi employed for the U.S. experiments in the areas of management, coordination, liaison, and real time operation are described. Some of the highlights associated with satellite utilization are given.

Launch and Landing of Russian Soyuz - Medical Support for US and Partner Astronauts

NASA Technical Reports Server (NTRS)

Menon, Anil

2017-01-01

Launching, landing, flight route, expeditions, Soyuz, near Kazakhstan USOS Crew Surgeon -Quarantine and direct care to crew before launch, then present in close proximity to launch for abort. IP Crew Surgeon -same Deputy Crew Surgeon -Back up for crew surgeon, care for immediate family, stationed at airport for helicopter abort response Russian based US doctor -Coordinate with SOS staff USOS Crew Surgeon -Nominal helicopter response and initial medical care and support during return on gulfstreamIPcenter dotP Crew Surgeon -same Deputy Crew Surgeon -Ballistic helicopter support Russian based US doctor -Coordinate with SOS staff Direct return doctor -Direct medical care on return flight

Primary care nursing role and care coordination: an observational study of nursing work in a community health center.

PubMed

Anderson, Daren R; St Hilaire, Daniel; Flinter, Margaret

2012-05-31

Care coordination is a core element of the Patient-Centered Medical Home and requires an effective, well educated nursing staff. A greater understanding of roles and tasks currently being carried out by nurses in primary care is needed to help practices determine how best to implement care coordination and transform into PCMHs. We conducted an observational study of primary care nursing in a Community Health Center by creating a classification schema for nursing responsibilities, directly observing and tracking nurses' work, and categorizing their activities. Ten nurses in eight different practice sites were observed for a total of 61 hours. The vast majority of nursing time was spent in vaccine and medication administration; telephone work; and charting and paper work, while only 15% of their time was spent in activity that was classified broadly as care coordination. Care coordination work appeared to be subsumed by other daily tasks, many of which could have been accomplished by other, lesser trained members of the health care team. Practices looking to implement care coordination need a detailed look at work flow, task assignments, and a critical assessment of staffing, adhering to the principal of each team member working to the highest level of his or her education and license. Care coordination represents a distinct responsibility that requires dedicated nursing time, separate from the day to day tasks in a busy practice. To fully support these new functions, reimbursement models are needed that support such non visit-based work and provide incentives to coordinate and manage complex cases, achieve improved clinical outcomes and enhance efficiency of the health system. This article describes our study methods, data collection, and analysis, results, and discussion about reorganizing nursing roles to promote care coordination.

Generalized Entropies and Legendre Duality

DTIC Science & Technology

2012-04-22

region because of their one-to-one functional relationship. The standard algorithm using projection of a polyhedron [29, 6] commonly works well to...coordinate system is chosen to realize the corresponding Voronoi diagrams. In this coordinate system with one extra complementary coordinate the polyhedron is...dually flat. Using this property, α-Voronoi diagrams on Rn+1+ is discussed in [31]. While both of the above methods require computation of the polyhedrons

The Air Force Interactive Meteorological System: A Research Tool for Satellite Meteorology

DTIC Science & Technology

1992-12-02

NFARnet itself is a subnet to the global computer network INTERNET that links nearly all U.S. government research facilities and universi- ties along...required input to a generalized mathematical solution to the satellite/earth coordinate transform used for earth location of GOES sensor data. A direct...capability also exists to convert absolute coordinates to relative coordinates for transformations associated with gridded fields. 3. Spatial objective

Parent Perspective on Care Coordination Services for Their Child with Medical Complexity

PubMed Central

Cady, Rhonda G.; Belew, John L.

2017-01-01

The overarching goal of care coordination is communication and co-management across settings. Children with medical complexity require care from multiple services and providers, and the many benefits of care coordination on health and patient experience outcomes have been documented. Despite these findings, parents still report their greatest challenge is communication gaps. When this occurs, parents assume responsibility for aggregating and sharing health information across providers and settings. A new primary-specialty care coordination partnership model for children with medical complexity works to address these challenges and bridge communication gaps. During the first year of the new partnership, parents participated in focus groups to better understand how they perceive communication and collaboration between the providers and services delivering care for their medically complex child. Our findings from these sessions reflect the current literature and highlight additional challenges of rural families, as seen from the perspective of the parents. We found that parents appreciate when professional care coordination is provided, but this is often the exception and not the norm. Additionally, parents feel that the local health system’s inability to care for their medically complex child results in unnecessary trips to urban-based specialty care. These gaps require a system-level approach to care coordination and, consequently, new paradigms for delivery are urgently needed. PMID:28587274

Parent Perspective on Care Coordination Services for Their Child with Medical Complexity.

PubMed

Cady, Rhonda G; Belew, John L

2017-06-06

The overarching goal of care coordination is communication and co-management across settings. Children with medical complexity require care from multiple services and providers, and the many benefits of care coordination on health and patient experience outcomes have been documented. Despite these findings, parents still report their greatest challenge is communication gaps. When this occurs, parents assume responsibility for aggregating and sharing health information across providers and settings. A new primary-specialty care coordination partnership model for children with medical complexity works to address these challenges and bridge communication gaps. During the first year of the new partnership, parents participated in focus groups to better understand how they perceive communication and collaboration between the providers and services delivering care for their medically complex child. Our findings from these sessions reflect the current literature and highlight additional challenges of rural families, as seen from the perspective of the parents. We found that parents appreciate when professional care coordination is provided, but this is often the exception and not the norm. Additionally, parents feel that the local health system's inability to care for their medically complex child results in unnecessary trips to urban-based specialty care. These gaps require a system-level approach to care coordination and, consequently, new paradigms for delivery are urgently needed.

20 CFR 404.1630 - Coordination with other agencies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Coordination with other agencies. 404.1630 Section 404.1630 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Determinations of Disability Administrative Responsibilities and Requirements...

20 CFR 416.1030 - Coordination with other agencies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Coordination with other agencies. 416.1030 Section 416.1030 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Determinations of Disability Administrative Responsibilities and Requirements...

Twinning in fcc lattice creates low-coordinated catalytically active sites in porous gold

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krajčí, Marian; Kameoka, Satoshi; Tsai, An-Pang

We describe a new mechanism for creation of catalytically active sites in porous gold. Samples of porous gold prepared by de-alloying Al{sub 2}Au exhibit a clear correlation between the catalytic reactivity towards CO oxidation and structural defects in the fcc lattice of Au. We have found that on the stepped (211) surfaces quite common twin boundary defects in the bulk structure of porous gold can form long close-packed rows of atoms with the coordination number CN = 6. DFT calculations confirm that on these low-coordinated Au sites dioxygen chemisorbs and CO oxidation can proceed via the Langmuir–Hinshelwood mechanism with themore » activation energy of 37 kJ/mol or via the CO–OO intermediate with the energy barrier of 19 kJ/mol. The existence of the twins in porous gold is stabilized by the surface energy.« less

On the interaction structure of linear multi-input feedback control systems. M.S. Thesis; [problem solving, lattices (mathematics)

NASA Technical Reports Server (NTRS)

Wong, P. K.

1975-01-01

The closely-related problems of designing reliable feedback stabilization strategy and coordinating decentralized feedbacks are considered. Two approaches are taken. A geometric characterization of the structure of control interaction (and its dual) was first attempted and a concept of structural homomorphism developed based on the idea of 'similarity' of interaction pattern. The idea of finding classes of individual feedback maps that do not 'interfere' with the stabilizing action of each other was developed by identifying the structural properties of nondestabilizing and LQ-optimal feedback maps. Some known stability properties of LQ-feedback were generalized and some partial solutions were provided to the reliable stabilization and decentralized feedback coordination problems. A concept of coordination parametrization was introduced, and a scheme for classifying different modes of decentralization (information, control law computation, on-line control implementation) in control systems was developed.

New nonlinear control algorithms for multiple robot arms

NASA Technical Reports Server (NTRS)

Tarn, T. J.; Bejczy, A. K.; Yun, X.

1988-01-01

Multiple coordinated robot arms are modeled by considering the arms as closed kinematic chains and as a force-constrained mechanical system working on the same object simultaneously. In both formulations, a novel dynamic control method is discussed. It is based on feedback linearization and simultaneous output decoupling technique. By applying a nonlinear feedback and a nonlinear coordinate transformation, the complicated model of the multiple robot arms in either formulation is converted into a linear and output decoupled system. The linear system control theory and optimal control theory are used to design robust controllers in the task space. The first formulation has the advantage of automatically handling the coordination and load distribution among the robot arms. In the second formulation, it was found that by choosing a general output equation it became possible simultaneously to superimpose the position and velocity error feedback with the force-torque error feedback in the task space.

The kinetic energy operator for distance-dependent effective nuclear masses: Derivation for a triatomic molecule.

PubMed

Khoma, Mykhaylo; Jaquet, Ralph

2017-09-21

The kinetic energy operator for triatomic molecules with coordinate or distance-dependent nuclear masses has been derived. By combination of the chain rule method and the analysis of infinitesimal variations of molecular coordinates, a simple and general technique for the construction of the kinetic energy operator has been proposed. The asymptotic properties of the Hamiltonian have been investigated with respect to the ratio of the electron and proton mass. We have demonstrated that an ad hoc introduction of distance (and direction) dependent nuclear masses in Cartesian coordinates preserves the total rotational invariance of the problem. With the help of Wigner rotation functions, an effective Hamiltonian for nuclear motion can be derived. In the derivation, we have focused on the effective trinuclear Hamiltonian. All necessary matrix elements are given in closed analytical form. Preliminary results for the influence of non-adiabaticity on vibrational band origins are presented for H 3 + .

Cell cycle-regulated PLEIADE/AtMAP65-3 links membrane and microtubule dynamics during plant cytokinesis.

PubMed

Steiner, Alexander; Rybak, Katarzyna; Altmann, Melina; McFarlane, Heather E; Klaeger, Susan; Nguyen, Ngoc; Facher, Eva; Ivakov, Alexander; Wanner, Gerhard; Kuster, Bernhard; Persson, Staffan; Braun, Pascal; Hauser, Marie-Theres; Assaad, Farhah F

2016-11-01

Cytokinesis, the partitioning of the cytoplasm following nuclear division, requires extensive coordination between cell cycle cues, membrane trafficking and microtubule dynamics. Plant cytokinesis occurs within a transient membrane compartment known as the cell plate, to which vesicles are delivered by a plant-specific microtubule array, the phragmoplast. While membrane proteins required for cytokinesis are known, how these are coordinated with microtubule dynamics and regulated by cell cycle cues remains unclear. Here, we document physical and genetic interactions between Transport Protein Particle II (TRAPPII) tethering factors and microtubule-associated proteins of the PLEIADE/AtMAP65 family. These interactions do not specifically affect the recruitment of either TRAPPII or MAP65 proteins to the cell plate or midzone. Rather, and based on single versus double mutant phenotypes, it appears that they are required to coordinate cytokinesis with the nuclear division cycle. As MAP65 family members are known to be targets of cell cycle-regulated kinases, our results provide a conceptual framework for how membrane and microtubule dynamics may be coordinated with each other and with the nuclear cycle during plant cytokinesis. © 2016 The Authors The Plant Journal © 2016 John Wiley & Sons Ltd.

Changes in measured vector magnetic fields when transformed into heliographic coordinates

NASA Technical Reports Server (NTRS)

Hagyard, M. J.

1987-01-01

The changes that occur in measured magnetic fields when they are transformed into a heliographic coordinate system are investigated. To carry out this investigation, measurements of the vector magnetic field of an active region that was observed at 1/3 the solar radius from disk center are taken, and the observed field is transformed into heliographic coordinates. Differences in the calculated potential field that occur when the heliographic normal component of the field is used as the boundary condition rather than the observed line-of-sight component are also examined. The results of this analysis show: (1) that the observed fields of sunspots more closely resemble the generally accepted picture of the distribution of umbral fields if they are displayed in heliographic coordinates; (2) that the differences in the potential calculations are less than 200 G in field strength and 20 deg in field azimuth outside sunspots; and (3) that differences in the two potential calculations in the sunspot areas are no more than 400 G in field strength but range from 60 to 80 deg in field azimuth in localized umbral areas.

Dynamic coupling between coordinates in a model for biomolecular isomerization

NASA Astrophysics Data System (ADS)

Ma, Ao; Nag, Ambarish; Dinner, Aaron R.

2006-04-01

To understand a complex reaction, it is necessary to project the dynamics of the system onto a low-dimensional subspace of physically meaningful coordinates. We recently introduced an automatic method for identifying coordinates that relate closely to stable-state commitment probabilities and successfully applied it to a model for biomolecular isomerization, the C7eq→αR transition of the alanine dipeptide [A. Ma and A. R. Dinner, J. Phys. Chem. B 109, 6769 (2005)]. Here, we explore approximate means for estimating diffusion tensors for systems subject to restraints in one and two dimensions and then use the results together with an extension of Kramers theory for unimolecular reaction rates [A. Berezhkovskii and A. Szabo, J. Chem. Phys. 122, 014503 (2005)] to show explicitly that both the potential of mean force and the diffusion tensor are essential for describing the dynamics of the alanine dipeptide quantitatively. In particular, the signficance of off-diagonal elements of the diffusion tensor suggests that the coordinates of interest are coupled by the hydrodynamic-like response of the bath of remaining degrees of freedom.

Securing recipiency in workplace meetings: Multimodal practices

PubMed Central

Ford, Cecilia E.; Stickle, Trini

2013-01-01

As multiparty interactions with single courses of coordinated action, workplace meetings place particular interactional demands on participants who are not primary speakers (e.g. not chairs) as they work to initiate turns and to interactively coordinate with displays of recipiency from co-participants. Drawing from a corpus of 26 hours of videotaped workplace meetings in a midsized US city, this article reports on multimodal practices – phonetic, prosodic, and bodily-visual – used for coordinating turn transition and for consolidating recipiency in these specialized speech exchange systems. Practices used by self-selecting non-primary speakers as they secure turns in meetings include displays of close monitoring of current speakers’ emerging turn structure, displays of heightened interest as current turns approach possible completion, and turn initiation practices designed to pursue and, in a fine-tuned manner, coordinate with displays of recipiency on the parts of other participants as well as from reflexively constructed ‘target’ recipients. By attending to bodily-visual action, as well as phonetics and prosody, this study contributes to expanding accounts for turn taking beyond traditional word-based grammar (i.e. lexicon and syntax). PMID:24976789

Heterogeneous Coordination Environments in Lithium-Neutralized Ionomers Identified Using 1H and 7Li MAS NMR

PubMed Central

Alam, Todd M.; Jenkins, Janelle E.; Bolintineanu, Dan S.; Stevens, Mark J.; Frischknecht, Amalie L.; Buitrago, C. Francisco; Winey, Karen I.; Opper, Kathleen L.; Wagener, Kenneth B.

2012-01-01

The carboxylic acid proton and the lithium coordination environments for precise and random Li-neutralized polyethylene acrylic acid P(E-AA) ionomers were explored using high speed solid-state 1H and 7Li MAS NMR. While the 7Li NMR revealed only a single Li coordination environment, the chemical shift temperature variation was dependent on the precise or random nature of the P(E-AA) ionomer. The 1H MAS NMR revealed two different carboxylic acid proton environments in these materials. By utilizing 1H-7Li rotational echo double resonance (REDOR) MAS NMR experiments, it was demonstrated that the proton environments correspond to different average 1H-7Li distances, with the majority of the protonated carboxylic acids having a close through space contact with the Li. Molecular dynamics simulations suggest that the shortest 1H-7Li distance corresponds to un-neutralized carboxylic acids directly involved in the coordination environment of Li clusters. These solid-state NMR results show that heterogeneous structural motifs need to be included when developing descriptions of these ionomer materials.

Relaxation of structural parameters and potential coefficients of nonrigid molecules. General symmetry properties and application to ab initio study of 1,2-difluoroethane

NASA Astrophysics Data System (ADS)

Ha, T.-K.; Günthard, H. H.

1989-07-01

Structural parameters like bond length, bond angles, etc. and harmonic and anharmonic potential coefficients of molecules with internal rotation, inversion or puckering modes are generally assumed to vary with the large amplitude internal coordinates in a concerted manner (relaxation). Taking the coordinate vectors of the nuclear configuration of semirigid molecules with relaxation (SRMRs) as functions of relaxing structural parameters and finite amplitude internal coordinate, the isometric group of SRMRs is discussed and the irreducible representations of the latter are shown to classify into engendered and nonengendered ones. On this basis a concept of equivalent sets of nuclei SRMRs is introduced and an analytical expression is derived which defines the most general functional form of relaxation increments of all common types of structural parameters compatible with isometric symmetry. This formula is shown to be a close analog of an analytical expression defining the transformations induced by the isometric group of infinitesimal internal coordinates associated with typical structural parameters. Furthermore analogous formulae are given for the most general form of the relaxation of harmonic potential coefficients as a function of finite internal coordinates. The general relations are illustrated by ab initio calculations for 1,2-difluoroethane at the MP4/DZP//HF/4-31G* level for twelve values of the dihedral angle including complete structure optimization. The potential to internal rotation is found to be in essential agreement with experimentally derived data. For a complete set of ab initio structural parameters the associated relaxation increments are represented as Fourier series, which are shown to confirm the form predicted by the general formula and the isometric group of 1,2-difluoroethane. Depending on type of the structural parameters (bond length, bond angles, etc.), the associated relaxation increments appear to follow some simple rules. Similarly a complete set of harmonic potential coefficients derived from the ab initio calculations will be analyzed in terms of Fourier series and shown to conform to the symmetry requirements of the symmetry group. Relaxation of potential coefficients is found to amount to up to ≈5% for some types of diagonal and nondiagonal terms and to reflect certain "topological" rules similar to regularities of harmonic potential constants of quasi-rigid molecules found in empirical determinations of valence force fields.

50 CFR 300.36 - Closed area stowage requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Closed area stowage requirements. 300.36... REGULATIONS South Pacific Tuna Fisheries § 300.36 Closed area stowage requirements. At all times while a vessel is in a Closed Area, the fishing gear of the vessel shall be stowed in a manner as not to be...

An EXAFS study of zinc coordination in microbial cells.

PubMed

Webb, S M; Gaillard, J F; Jackson, B E; Stahl, D A

2001-03-01

Five microbes were isolated from metal amended enrichment cultures derived from the sediments of a lake contaminated by a zinc smelter. Each of these organisms was grown in pure culture in the presence of zinc. Quick Extended X-ray Absorption Fine Structure (QEXAFS) spectroscopy was used to investigate the average coordination environment of the zinc associated with the microbial biomass. Fitting of the first coordination shell of zinc shows that significant differences exist for each microbial species examined. The coordination environment of zinc varies between sulfurs to six-fold nitrogen/oxygen. with two microbial strains showing mixed coordination shells. Further study is required in order to characterize these sites and their locations within the cell.

String solutions in spherically-symmetric f(R) gravity vacuum

NASA Astrophysics Data System (ADS)

Dil, Emre

Dynamical evolution of the cosmic string in a spherically symmetric f(R) gravity vacuum is studied for a closed and straight string. We first set the background spacetime metric for a constant curvature scalar R = R0, and obtain the Killing fields for it. Using the standard gauge coordinates and constraints for both closed and straight strings, we present the equation of motions and find the solutions of them. We then analyze the dynamics of the string by studying the behavior of the string radius and periastron radius, with respect to both proper time and azimuthal angle, for various values of f(R) functions. Consequently, we conclude that the value of f(R) dramatically affects the closed string collapse time and the straight string angular deviation.

Altruism in clinical research: coordinators' orientation to their professional roles.

PubMed

Fisher, Jill A; Kalbaugh, Corey A

2012-01-01

Research coordinators have significant responsibilities in clinical trials that often require them to find unique ways to manage their jobs, thus reshaping their professional identities. The purpose of this study was to identify how research coordinators manage role and ethical conflicts within clinical research trials. A qualitative study combining observation and 63 semistructured interviews at 25 research organizations was used. Altruism is a recurring theme in how research coordinators define and view their work. Altruism is adopted by research coordinators to: (1) Teach patient-subjects the appropriate reasons to participate in clinical research, (2) minimize the conflict between research and care, and (3) contest the undervaluation of coordinating. Altruism is a strategy used to handle the various conflicts they experience in a difficult job, and it has become part of the professional identity of clinical research coordinators. Copyright © 2012 Elsevier Inc. All rights reserved.

40 CFR 761.77 - Coordinated approval.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 761.77 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS Storage and Disposal § 761.77 Coordinated approval. (a) General requirements. Notwithstanding any other provision of this part, the EPA Regional Administrator for the Region in which a PCB disposal or...

40 CFR 761.77 - Coordinated approval.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 761.77 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS Storage and Disposal § 761.77 Coordinated approval. (a) General requirements. Notwithstanding any other provision of this part, the EPA Regional Administrator for the Region in which a PCB disposal or...

40 CFR 761.77 - Coordinated approval.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 761.77 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS Storage and Disposal § 761.77 Coordinated approval. (a) General requirements. Notwithstanding any other provision of this part, the EPA Regional Administrator for the Region in which a PCB disposal or...

40 CFR 761.77 - Coordinated approval.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 761.77 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL... PROHIBITIONS Storage and Disposal § 761.77 Coordinated approval. (a) General requirements. Notwithstanding any other provision of this part, the EPA Regional Administrator for the Region in which a PCB disposal or...