7 CFR 1160.112 - Research.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 9 2013-01-01 2013-01-01 false Research. 1160.112 Section 1160.112 Agriculture... Definitions § 1160.112 Research. Research means market research to support advertising and promotion efforts, including educational activities, research directed to product characteristics, and product development...

7 CFR 1160.112 - Research.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 9 2010-01-01 2009-01-01 true Research. 1160.112 Section 1160.112 Agriculture... Definitions § 1160.112 Research. Research means market research to support advertising and promotion efforts, including educational activities, research directed to product characteristics, and product development...

7 CFR 1160.112 - Research.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 9 2014-01-01 2013-01-01 true Research. 1160.112 Section 1160.112 Agriculture... Definitions § 1160.112 Research. Research means market research to support advertising and promotion efforts, including educational activities, research directed to product characteristics, and product development...

7 CFR 1160.112 - Research.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 9 2011-01-01 2011-01-01 false Research. 1160.112 Section 1160.112 Agriculture... Definitions § 1160.112 Research. Research means market research to support advertising and promotion efforts, including educational activities, research directed to product characteristics, and product development...

Direct-to-Consumer Marketing: A Complementary Approach to Traditional Dissemination and implementation Efforts for Mental Health and Substance Abuse Interventions

PubMed Central

Becker, Sara J.

2014-01-01

The overall chasm between those who need treatment for mental health and substance abuse (M/SU) and those who receive effective treatment consists of two, interrelated gaps: the research-to-practice gap and the treatment gap. Prior efforts to disseminate evidence-based practice (EBP) for M/SU have predominantly targeted the research-to-practice gap, by focusing efforts toward treatment providers. This article introduces direct-to-consumer (DTC) marketing that targets patients and caregivers as a complementary approach to existing dissemination efforts. Specific issues discussed include: rationale for DTC marketing based on the concept of push versus pull marketing; overview of key stakeholders involved in DTC marketing; and description of the Marketing Mix planning framework. The applicability of these issues to the dissemination of EBP for M/SU is discussed. PMID:25937710

DOE Office of Scientific and Technical Information (OSTI.GOV)

INSTRUMENTATION DIVISION STAFF

To develop state-of-the-art instrumentation required for experimental research programs at BNL, and to maintain the expertise and facilities in specialized high technology areas essential for this work. Development of facilities is motivated by present BNL research programs and anticipated future directions of BNL research. The Division's research efforts also have a significant impact on programs throughout the world that rely on state-of-the-art radiation detectors and readout electronics. Our staff scientists are encouraged to: Become involved in challenging problems in collaborations with other scientists; Offer unique expertise in solving problems; and Develop new devices and instruments when not commercially available. Scientistsmore » from other BNL Departments are encouraged to bring problems and ideas directly to the Division staff members with the appropriate expertise. Division staff is encouraged to become involved with research problems in other Departments to advance the application of new ideas in instrumentation. The Division Head integrates these efforts when they evolve into larger projects, within available staff and budget resources, and defines the priorities and direction with concurrence of appropriate Laboratory program leaders. The Division Head also ensures that these efforts are accompanied by strict adherence to all ES and H regulatory mandates and policies of the Laboratory. The responsibility for safety and environmental protection is integrated with supervision of particular facilities and conduct of operations.« less

LES, DNS and RANS for the analysis of high-speed turbulent reacting flows

NASA Technical Reports Server (NTRS)

Givi, Peyman

1994-01-01

The objective of this research is to continue our efforts in advancing the state of knowledge in Large Eddy Simulation (LES), Direct Numerical Simulation (DNS), and Reynolds Averaged Navier Stokes (RANS) methods for the analysis of high-speed reacting turbulent flows. In the first phase of this research, conducted within the past six months, focus was in three directions: RANS of turbulent reacting flows by Probability Density Function (PDF) methods, RANS of non-reacting turbulent flows by advanced turbulence closures, and LES of mixing dominated reacting flows by a dynamics subgrid closure. A summary of our efforts within the past six months of this research is provided in this semi-annual progress report.

Compatibility between wood production and other values and uses on forested lands: a problem analysis.

Treesearch

Charles E. Peterson; Robert A. Monserud

2002-01-01

We provide background documentation for the Pacific Northwest Research Station’s Wood Compatibility Initiative, a 5-year multidisciplinary research effort that began in response to 1997 Congressional direction. This problem analysis was the initial effort to examine the state of knowledge regarding compatibility between wood production and other values and to develop a...

Technology and Research Requirements for Combating Human Trafficking: Enhancing Communication, Analysis, Reporting, and Information Sharing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kreyling, Sean J.; West, Curtis L.; Olson, Jarrod

2011-03-17

DHS’ Science & Technology Directorate directed PNNL to conduct an exploratory study on the domain of human trafficking in the Pacific Northwest in order to examine and identify technology and research requirements for enhancing communication, analysis, reporting, and information sharing – activities that directly support efforts to track, identify, deter, and prosecute human trafficking – including identification of potential national threats from smuggling and trafficking networks. This effort was conducted under the Knowledge Management Technologies Portfolio as part of the Integrated Federal, State, and Local/Regional Information Sharing (RISC) and Collaboration Program.

Subtask 7.1 - Strategic Studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thomas Erickson

2009-03-30

The Energy & Environmental Research Center (EERC) has recently completed 11 years of research through the Cooperative Agreement with the U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) focused on fossil energy technology development and demonstration. To support a significant number of the different activities being considered within all of our research contracts with NETL, a subtask (7.1 Strategic Studies) was created to focus on small research efforts that came up throughout the year which would support an existing EERC-NETL project or would help to develop a new concept for inclusion in future efforts. Typical efforts conducted undermore » this task were usually between $15,000 and $60,000 in scope and had time lines of less than 6 months. A limited number of larger studies were also conducted, generally at the direct request of NETL. Over the life of this task, 46 projects were conducted. These efforts ranged from quick experiments to gain fundamental knowledge to support a current effort, to literature reviews, to a few larger engineering efforts.« less

Rivers and streams in the media: a content analysis of ecosystem services

EPA Science Inventory

While ecosystem services research has become common, few efforts are directed toward in-depth understanding of the specific ecological quantities people value. Environmental communications as well as ecological monitoring and analysis efforts could be enhanced by such information...

Commercial Building Partnerships Replication and Diffusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Antonopoulos, Chrissi A.; Dillon, Heather E.; Baechler, Michael C.

2013-09-16

This study presents findings from survey and interview data investigating replication efforts of Commercial Building Partnership (CBP) partners that worked directly with the Pacific Northwest National Laboratory (PNNL). PNNL partnered directly with 12 organizations on new and retrofit construction projects, which represented approximately 28 percent of the entire U.S. Department of Energy (DOE) CBP program. Through a feedback survey mechanism, along with personal interviews, PNNL gathered quantitative and qualitative data relating to replication efforts by each organization. These data were analyzed to provide insight into two primary research areas: 1) CBP partners’ replication efforts of technologies and approaches used inmore » the CBP project to the rest of the organization’s building portfolio (including replication verification), and, 2) the market potential for technology diffusion into the total U.S. commercial building stock, as a direct result of the CBP program. The first area of this research focused specifically on replication efforts underway or planned by each CBP program participant. Factors that impact replication include motivation, organizational structure and objectives firms have for implementation of energy efficient technologies. Comparing these factors between different CBP partners revealed patterns in motivation for constructing energy efficient buildings, along with better insight into market trends for green building practices. The second area of this research develops a diffusion of innovations model to analyze potential broad market impacts of the CBP program on the commercial building industry in the United States.« less

Lessons learned from research and surveillance directed at highly pathogenic influenza A viruses in wild birds inhabiting North America

USGS Publications Warehouse

Ramey, Andy M.; DeLiberto, Thomas J.; Berhane, Yohannes; Swayne, David E.; Stallknecht, David E.

2018-01-01

Following detections of highly pathogenic (HP) influenza A viruses (IAVs) in wild birds inhabiting East Asia after the turn of the millennium, the intensity of sampling of wild birds for IAVs increased throughout much of North America. The objectives for many research and surveillance efforts were directed towards detecting Eurasian origin HP IAVs and understanding the potential of such viruses to be maintained and dispersed by wild birds. In this review, we highlight five important lessons learned from research and surveillance directed at HP IAVs in wild birds inhabiting North America: (1) Wild birds may disperse IAVs between North America and adjacent regions via migration, (2) HP IAVs can be introduced to wild birds in North America, (3) HP IAVs may cross the wild bird-poultry interface in North America, (4) The probability of encountering and detecting a specific virus may be low, and (5) Population immunity of wild birds may influence HP IAV outbreaks in North America. We review empirical support derived from research and surveillance efforts for each lesson learned and, furthermore, identify implications for future surveillance efforts, biosecurity, and population health. We conclude our review by identifying five additional areas in which we think future mechanistic research relative to IAVs in wild birds in North America are likely to lead to other important lessons learned in the years ahead.

Lessons learned from research and surveillance directed at highly pathogenic influenza A viruses in wild birds inhabiting North America.

PubMed

Ramey, Andrew M; DeLiberto, Thomas J; Berhane, Yohannes; Swayne, David E; Stallknecht, David E

2018-05-01

Following detections of highly pathogenic (HP) influenza A viruses (IAVs) in wild birds inhabiting East Asia after the turn of the millennium, the intensity of sampling of wild birds for IAVs increased throughout much of North America. The objectives for many research and surveillance efforts were directed towards detecting Eurasian origin HP IAVs and understanding the potential of such viruses to be maintained and dispersed by wild birds. In this review, we highlight five important lessons learned from research and surveillance directed at HP IAVs in wild birds inhabiting North America: (1) Wild birds may disperse IAVs between North America and adjacent regions via migration, (2) HP IAVs can be introduced to wild birds in North America, (3) HP IAVs may cross the wild bird-poultry interface in North America, (4) The probability of encountering and detecting a specific virus may be low, and (5) Population immunity of wild birds may influence HP IAV outbreaks in North America. We review empirical support derived from research and surveillance efforts for each lesson learned and, furthermore, identify implications for future surveillance efforts, biosecurity, and population health. We conclude our review by identifying five additional areas in which we think future mechanistic research relative to IAVs in wild birds in North America are likely to lead to other important lessons learned in the years ahead. Published by Elsevier Inc.

GLCF: Research

Science.gov Websites

Global Land Cover Facility About GLCF Research Publications Data & Products Gallery Library Services Contact Site Map Go Research The Global Land Cover Facility is a research center focusing on the GLCF in developing forest change products. Past research efforts were directed at boreal forests in

Geysers advanced direct contact condenser research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Henderson, J.; Bahning, T.; Bharathan, D.

1997-12-31

The first geothermal application of the Advanced Direct Contact Condenser (ADCC) technology developed by the National Renewable Energy Laboratory (NREL) is now operational and is being tested at The Geysers Power Plant Unit 11. This major research effort is being supported through the combined efforts of NREL, The Department of Energy (DOE), and Pacific Gas and Electric (PG&E). NREL and PG&E have entered into a Cooperative Research And Development Agreement (CRADA) for a project to improve the direct-contact condenser performance at The Geysers Power Plant. This project is the first geothermal adaptation of an advanced condenser design developed for themore » Ocean Thermal Energy Conversion (OTEC) systems. PG&E expects this technology to improve power plant performance and to help extend the life of the steam field by using steam more efficiently. In accordance with the CRADA, no money is transferred between the contracting parties. In this case the Department of Energy is funding NREL for their efforts in this project and PG&E is contributing funds in kind. Successful application of this technology at The Geysers will provide a basis for NREL to continue to develop this technology for other geothermal and fossil power plant systems.« less

The Nursing Home Culture-Change Movement: Recent Past, Present, and Future Directions for Research

ERIC Educational Resources Information Center

Rahman, Anna N.; Schnelle, John F.

2008-01-01

This article uses a retrospective approach to critique the research base underlying the nursing home culture-change movement--an effort to radically transform the nation's nursing homes by delivering resident-directed care and empowering staff. The article traces the development of the movement from its inception 10 years ago to 2005, when the…

Refinement of moisture calibration curves for nuclear gage.

DOT National Transportation Integrated Search

1973-01-01

Over the last three years the Virginia Highway Research Council has directed a research effort toward improving the method of determining the moisture content of soils with a nuclear gage. The first task in this research was the determination of the ...

Current limitations into the application of virtual reality to mental health research.

PubMed

Huang, M P; Alessi, N E

1998-01-01

Virtual Reality (VR) environments have significant potential as a tool in mental health research, but are limited by technical factors and by mental health research factors. Technical difficulties include cost and complexity of virtual environment creation. Mental health research difficulties include current inadequacy of standards to specify needed details for virtual environment design. Technical difficulties are disappearing with technological advances, but the mental health research difficulties will take a concerted effort to overcome. Some of this effort will need to be directed at the formation of collaborative projects and standards for how such collaborations should proceed.

The Mission of the Polish Universities in Environmental Preservation.

ERIC Educational Resources Information Center

Mazurkiewicz, Boleslaw K.

In order to reduce pollution, secure long-term energy needs, retard the depletion of non-renewable resources, and harmonize industrialization with the vulnerable environment, Polish universities are directing their efforts toward intensification of ecological education and intensification of research activities. Its efforts are connected with…

The National Plan for Research and Development In Support of Critical Infrastructure Protection

DTIC Science & Technology

2004-01-01

vulnerabilities and highlight areas for improvement. As part of this effort, CIP &CP has cre- ated a research and development agenda aimed at improving...Infrastructure Protection Research and Development Plan 13 LONG-TERM DIRECTION PROVIDED BY THE CIP R&D PLAN The creation of a national critical...Research and Development Plan 20 Mapping to Other National R&D Plans The many R&D plans outside the direct context of CIP underway within DHS, other

Overview of the United States Department of Energy's ARM (Atmospheric Radiation Measurement) Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stokes, G.M.; Tichler, J.L.

The Department of Energy (DOE) is initiating a major atmospheric research effort, the Atmospheric Radiation Measurement Program (ARM). The program is a key component of DOE's research strategy to address global climate change and is a direct continuation of DOE's decade-long effort to improve the ability of General Circulation Models (GCMs) to provide reliable simulations of regional, and long-term climate change in response to increasing greenhouse gases. The effort is multi-disciplinary and multi-agency, involving universities, private research organizations and more than a dozen government laboratories. The objective of the ARM Research is to provide an experimental testbed for the studymore » of important atmospheric effects, particularly cloud and radiative processes, and to test parameterizations of these processes for use in atmospheric models. This effort will support the continued and rapid improvement of GCM predictive capability. 2 refs.« less

Research Methods in the Language Arts.

ERIC Educational Resources Information Center

National Conference on Research in English.

The articles comprising this bulletin report the status of research methods in the English language arts and indicate promising directions for further effort. Ralph C. Staiger discusses the range of language arts research and points out the strengths and weaknesses of various research techniques. Theodore Clymer examines the essential…

The School Finance Reform Movement: Implications for School Business Administration.

ERIC Educational Resources Information Center

Jordan, K. Forbis

In this speech, the author summarizes the economic and political issues relating to the current interest in school finance reform and discusses the research efforts of the National Educational Finance Project. He focuses on those efforts of direct relevance to school business administration -- cost differentials among educational programs,…

Rapid near-optimal aerospace plane trajectory generation and guidance

NASA Technical Reports Server (NTRS)

Calise, A. J.; Corban, J. E.; Markopoulos, N.

1991-01-01

Effort was directed toward the problems of the real time trajectory optimization and guidance law development for the National Aerospace Plane (NASP) applications. In particular, singular perturbation methods were used to develop guidance algorithms suitable for onboard, real time implementation. The progress made in this research effort is reported.

Undergraduate Research in the Dartmouth Economics Department

ERIC Educational Resources Information Center

Feyrer, James

2017-01-01

One of the key components to the undergraduate research enterprise at Dartmouth is the recognition that learning to do research requires both directed instruction and learning by doing. The economics faculty have tailored a fruitful undergraduate research program based on this philosophy, and this article describes these efforts while also…

Why do we need to standardize no-tillage research?

USDA-ARS?s Scientific Manuscript database

No-tillage / conservation agricultural systems research has now been performed for more than half a century in many countries around the world, but few efforts have been made to standardize research methodology. This has led to a situation where no-tillage research results have often not been direct...

Large eddy simulations and direct numerical simulations of high speed turbulent reacting flows

NASA Technical Reports Server (NTRS)

Givi, Peyman; Madnia, Cyrus K.; Steinberger, Craig J.

1990-01-01

This research is involved with the implementation of advanced computational schemes based on large eddy simulations (LES) and direct numerical simulations (DNS) to study the phenomenon of mixing and its coupling with chemical reactions in compressible turbulent flows. In the efforts related to LES, a research program to extend the present capabilities of this method was initiated for the treatment of chemically reacting flows. In the DNS efforts, the focus is on detailed investigations of the effects of compressibility, heat release, and non-equilibrium kinetics modelings in high speed reacting flows. Emphasis was on the simulations of simple flows, namely homogeneous compressible flows, and temporally developing high speed mixing layers.

When to Randomize: Lessons from Independent Impact Evaluation of Reading to Learn (RtL) Programme to Improve Literacy and Numeracy in Kenya and Uganda

ERIC Educational Resources Information Center

Oketch, Moses; Ngware, Moses; Mutisya, Maurice; Kassahun, Admassu; Abuya, Benta; Musyoka, Peter

2014-01-01

In East Africa, there is great effort directed toward ensuring that there is learning and value for money invested in universal education policies initiated over the past decade. Kenya and Uganda are two countries that typify this effort. The effort includes the work of research organisations such as Uwezo, which assess learning levels; RTI, which…

A comprehensive examination of naturalistic lane-changes

DOT National Transportation Integrated Search

2004-03-01

This research effort provided valuable insight into the nature and severity of lane changes in a naturalistic driving environment. Sixteen commuters who normally drove more than 25 miles (40 km) in each direction participated. The two research vehicl...

Reduced Delay of Gratification and Effortful Control among Young Children with Autism Spectrum Disorders

ERIC Educational Resources Information Center

Faja, Susan; Dawson, Geraldine

2015-01-01

We explored internal control of behavior using direct observation and parent report. Previous research has found that both the delay of gratification task and parent-reported effortful control predict later social ability and more positive outcomes in typically developing children. Children with autism spectrum disorder have previously been…

HAZARDOUS WASTE IDENTIFICATION

EPA Science Inventory

This research is in direct support of the regulatory reform efforts under the Hazarous Waste Identification (HWIR) and is related to the development of national "exit levels" based on sound scientific data and models. Research focuses on developing a systems approach to modelin...

New Directions for Biosciences Research in Agriculture. High-Reward Opportunities.

ERIC Educational Resources Information Center

National Academy of Sciences - National Research Council, Washington, DC. Board on Agriculture.

To aid in the effort to define comprehensive long-range planning goals in bioregulation, the Agricultural Research Service (ARS) asked the Board of Agriculture of the National Research Council to undertake a study of the ARS research programs concerned with bioregulation. (For the purposes of this study bioregulation was interpreted broadly to be…

New Mexico energy research resource registry. Researchers and facilities

NASA Technical Reports Server (NTRS)

1975-01-01

Human resources and facilities in New Mexico available for application to energy research and development are listed. Information regarding individuals with expertise in the environmental, socio-economic, legal, and management and planning areas of the energy effort is included as well as those scientists, engineers, and technicians involved directly in energy research and development.

Telerobot task planning and reasoning: Introduction to JPL artificial intelligence research

NASA Technical Reports Server (NTRS)

Atkinson, D. J.

1987-01-01

A view of the capabilities and areas of artificial intelligence research which are required for autonomous space telerobotics extending through the year 2000 is given. In the coming years, JPL will be conducting directed research to achieve these capabilities, as well as drawing heavily on collaborative efforts conducted with other research laboratories.

Morphoproteomic-Guided Host-Directed Therapy for Tuberculosis.

PubMed

Brown, Robert E; Hunter, Robert L; Hwang, Shen-An

2017-01-01

In an effort to develop more effective therapy for tuberculosis (TB), research efforts are looking toward host-directed therapy, reprograming the body's natural defenses to better control the infection. While significant progress is being made, the efforts are limited by lack of understanding of the pathology and pathogenesis of adult type TB disease. We have recently published evidence that the developing lesions in human lungs are focal endogenous lipid pneumonia that constitutes a region of local susceptibility in a person with strong systemic immunity. Since most such lesions regress spontaneously, the ability to study them directly with immunohistochemistry provides means to investigate why some progress to clinical disease while others asymptomatically regress. Furthermore, this should enable us to develop more effective host-directed therapies. Morphoproteomics has proven to be an effective means of characterizing protein expression that can be used to identify metabolic pathways, which can lead to more effective therapies. The purpose of this perspective will argue that using morphoproteomics on human TB lung tissue is a particularly promising method to direct selection of host-directed therapeutics.

The Public Stigma of Mental Illness: What Do We Think; What Do We Know; What Can We Prove?

PubMed Central

Pescosolido, Bernice

2015-01-01

By the 1990s, sociology faced a frustrating paradox. Classic work on mental illness stigma and labeling theory reinforced that the “mark” of mental illness created prejudice and discrimination for individuals and family members. Yet that foundation, coupled with deinstitutionalization of mental health care, produced contradictory responses. Claims that stigma was dissipating were made, while others argued that intervention efforts were needed to reduce stigma. While signaling the critical role of theory-based research in establishing the pervasive effects of stigma, both claims directed resources away from social science research. Yet the contemporary scientific foundation underlying both claims was weak. A reply came in a resurgence of research directed toward mental illness stigma nationally and internationally, bringing together researchers from different disciplines for the first time. The author reports on the general population’s attitudes, beliefs, and behavioral dispositions that targeted public stigma and implications for the next decade of research and intervention efforts. PMID:23325423

The balancing act: experts' opinions about the relative resourcing of tobacco control efforts for the general population versus disadvantaged populations.

PubMed

Paul, Christine Louise; Bonevski, Billie; Turon, Heidi Erin; Bryant, Jamie

2012-07-01

Despite the persistent socioeconomic gradient associated with smoking, little is known about how to 'close the gap'. There is a debate regarding the implications of directing resources away from general population efforts towards disadvantaged groups. The study explored views of those with expertise in tobacco control about the appropriate balance of tobacco control resourcing between the general population and disadvantaged groups. A Web-based survey of 192 respondents (response rate 65%) working in tobacco control in Australia and New Zealand was completed. Respondents were sampled from the Australian and New Zealand Tobacco Control Contact List and a literature search. Respondents were asked to allocate a hypothetical budget for: (a) anti-tobacco mass media campaigns; and (b) tobacco control research. The vast majority (93%) of respondents believed that some tobacco control resources should be specifically directed towards disadvantaged groups. Respondents believed up to half of mass media resources should be directed towards disadvantaged groups. In the case of tobacco control research, the median allocation to the general population was approximately one-third of a hypothetical research budget. It appears there is a desire among the Australian and New Zealand tobacco control community for substantial effort to be directed towards disadvantaged groups. It is important to develop an evidence base to ensure an efficient and equitable approach to balancing the potentially competing demands of general population versus disadvantaged group activities in relation to tobacco control. © 2012 Australasian Professional Society on Alcohol and other Drugs.

Nevada National Security Site: Site-Directed Research and Development (SDRD) Fiscal Year 2015 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bender, Howard A.

This report presents results of multiple research projects, new and ongoing, funded under the Site-Directed Research and Development Program for the Nevada National Security Site during federal fiscal year 2015. The Site's legacy capabilities in remote sensing combined with new paradigms for emergency response and consequence management help drive the need to develop advanced aerial sensor platforms. Likewise, dynamic materials science is a critical area of scientific research for which basic physics issues are still unresolved. New methods of characterizing materials in extreme states are vitally needed, and these efforts are paving the way with new knowledge. Projects selected inmore » FY 2015 for the Exploratory Research portfolio exhibit a strong balance of NNSS mission relevance. Geoscience, seismology, and techniques for detecting underground nuclear events are still essential focus areas. Many of the project reports in the second major section of this annual report are ongoing continuations in multi-year lifecycles. Diagnostic techniques for stockpile and nuclear security science figured prominently as well, with a few key efforts coming to fruition, such as phase transition detection. In other areas, modeling efforts toward better understanding plasma focus physics has also started to pay dividends for major program needs.« less

Research Priorities for Economic Analyses of Prevention: Current Issues & Future Directions

PubMed Central

Crowley, D. Max; Hill, Laura Griner; Kuklinski, Margaret R.; Jones, Damon E.

2013-01-01

In response to growing interest in economic analyses of prevention efforts, a diverse group of prevention researchers, economists, and policy analysts convened a scientific panel, on “Research Priorities in Economic Analysis of Prevention” at the 19th annual conference of the Society for Prevention Research. The panel articulated four priorities that, if followed in future research, would make economic analyses of prevention efforts easier to compare and more relevant to policymakers, and community stakeholders. These priorities are: (1) increased standardization of evaluation methods, (2) improved economic valuation of common prevention outcomes, (3) expanded efforts to maximize evaluation generalizability and impact, as well as (4) enhanced transparency and communicability of economic evaluations. In this paper we define three types of economic analyses in prevention, provide context and rationale for these four priorities as well as related sub-priorities, and discuss the challenges inherent in meeting them. PMID:23963624

Examining the Dimensionality of Effortful Control in Preschool Children and Its Relation to Academic and Socioemotional Indicators

ERIC Educational Resources Information Center

Allan, Nicholas P.; Lonigan, Christopher J.

2011-01-01

Effortful control (EC) is an important developmental construct, associated with socioemotional growth, academic performance, and psychopathology. EC is defined as the ability to execute goal-directed behavior to inhibit or delay a prepotent response in favor of a subdominant response. Extant research indicates that EC may be multidimensional.…

The First Big Wave of Astronomy Education Research Dissertations and Some Directions for Future Research Efforts

ERIC Educational Resources Information Center

Slater, Timothy F.

2008-01-01

The past several years have presented the astronomy education research community with a host of foundational research dissertations in the teaching and learning of astronomy. These PhD candidates have been studying the impact of instructional innovations on student learning and systematically validating astronomy learning assessment instruments,…

Formal Analysis of the Remote Agent Before and After Flight

NASA Technical Reports Server (NTRS)

Havelund, Klaus; Lowry, Mike; Park, SeungJoon; Pecheur, Charles; Penix, John; Visser, Willem; White, Jon L.

2000-01-01

This paper describes two separate efforts that used the SPIN model checker to verify deep space autonomy flight software. The first effort occurred at the beginning of a spiral development process and found five concurrency errors early in the design cycle that the developers acknowledge would not have been found through testing. This effort required a substantial manual modeling effort involving both abstraction and translation from the prototype LISP code to the PROMELA language used by SPIN. This experience and others led to research to address the gap between formal method tools and the development cycle used by software developers. The Java PathFinder tool which directly translates from Java to PROMELA was developed as part of this research, as well as automatic abstraction tools. In 1999 the flight software flew on a space mission, and a deadlock occurred in a sibling subsystem to the one which was the focus of the first verification effort. A second quick-response "cleanroom" verification effort found the concurrency error in a short amount of time. The error was isomorphic to one of the concurrency errors found during the first verification effort. The paper demonstrates that formal methods tools can find concurrency errors that indeed lead to loss of spacecraft functions, even for the complex software required for autonomy. Second, it describes progress in automatic translation and abstraction that eventually will enable formal methods tools to be inserted directly into the aerospace software development cycle.

LES, DNS and RANS for the analysis of high-speed turbulent reacting flows

NASA Technical Reports Server (NTRS)

Givi, Peyman; Taulbee, Dale B.; Adumitroaie, Virgil; Sabini, George J.; Shieh, Geoffrey S.

1994-01-01

The purpose of this research is to continue our efforts in advancing the state of knowledge in large eddy simulation (LES), direct numerical simulation (DNS), and Reynolds averaged Navier Stokes (RANS) methods for the computational analysis of high-speed reacting turbulent flows. In the second phase of this work, covering the period 1 Sep. 1993 - 1 Sep. 1994, we have focused our efforts on two research problems: (1) developments of 'algebraic' moment closures for statistical descriptions of nonpremixed reacting systems, and (2) assessments of the Dirichlet frequency in presumed scalar probability density function (PDF) methods in stochastic description of turbulent reacting flows. This report provides a complete description of our efforts during this past year as supported by the NASA Langley Research Center under Grant NAG1-1122.

32 CFR 34.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... nonexpendable personal property charged directly to the award having a useful life of more than one year and an... increasing knowledge or understanding in science and engineering. Applied research is defined as efforts that... that is charged directly to the award and that has a useful life of less than one year or an...

32 CFR 34.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... nonexpendable personal property charged directly to the award having a useful life of more than one year and an... increasing knowledge or understanding in science and engineering. Applied research is defined as efforts that... that is charged directly to the award and that has a useful life of less than one year or an...

Avoiding Neurological Pitfalls

ERIC Educational Resources Information Center

Crossland, John

2014-01-01

In the past, teaching has suffered from applying tentative research from neuroscience directly to the classroom. Even though the last decade has seen a step change in efforts to bring together education and neuroscience research, the dialogue is still in its infancy. What do you do if you want to learn more? What does the research really tell us?…

ARRIVE. Annual Review of Research in Vocational Education. Volume One.

ERIC Educational Resources Information Center

Wentling, Tim L., Ed.

This book represents a sampling of current research priorities in vocational education along with suggested directions for further education. In the first of the book's five sections, research efforts related to sex equity in vocational education are summarized by M. Eloise Murray. Both sex equity studies and sex affirmation studies are included…

Advanced Curation Activities at NASA: Preparing to Receive, Process, and Distribute Samples Returned from Future Missions

NASA Technical Reports Server (NTRS)

McCubbin, Francis M.; Zeigler, Ryan A.

2017-01-01

The Astromaterials Acquisition and Curation Office (henceforth referred to herein as NASA Curation Office) at NASA Johnson Space Center (JSC) is responsible for curating all of NASA's extraterrestrial samples. Under the governing document, NASA Policy Directive (NPD) 7100.10F JSC is charged with curation of all extraterrestrial material under NASA control, including future NASA missions. The Directive goes on to define Curation as including documentation, preservation, preparation, and distribution of samples for research, education, and public outreach. Here we briefly describe NASA's astromaterials collections and our ongoing efforts related to enhancing the utility of our current collections as well as our efforts to prepare for future sample return missions. We collectively refer to these efforts as advanced curation.

Advanced Curation Activities at NASA: Implications for Astrobiological Studies of Future Sample Collections

NASA Technical Reports Server (NTRS)

McCubbin, F. M.; Evans, C. A.; Fries, M. D.; Harrington, A. D.; Regberg, A. B.; Snead, C. J.; Zeigler, R. A.

2017-01-01

The Astromaterials Acquisition and Curation Office (henceforth referred to herein as NASA Curation Office) at NASA Johnson Space Center (JSC) is responsible for curating all of NASA's extraterrestrial samples. Under the governing document, NASA Policy Directive (NPD) 7100.10F JSC is charged with curation of all extraterrestrial material under NASA control, including future NASA missions. The Directive goes on to define Curation as including documentation, preservation, preparation, and distribution of samples for re-search, education, and public outreach. Here we briefly describe NASA's astromaterials collections and our ongoing efforts related to enhancing the utility of our current collections as well as our efforts to prepare for future sample return missions. We collectively refer to these efforts as advanced curation.

Bridging basic and clinical science with policy studies: The Partners with Transdisciplinary Tobacco Use Research Centers experience.

PubMed

Kobus, Kimberly; Mermelstein, Robin

2009-05-01

The Partners with Transdisciplinary Tobacco Use Research Centers (TTURCs) initiative was a transdisciplinary team-building program, funded by the Robert Wood Johnson Foundation, to expand the policy research capacity of the TTURCs. EXPANSION INTO POLICY RESEARCh: Policy research activities at the TTURCs fell into four broad domains: (a) health services research, (b) examination of the business case for cessation treatment and funding, (c) collaborative teams with key stakeholders, and (d) direct assessment of smoking-related policies. Examples of each domain are presented. Goals of the initiative included efforts to foster collaborative, transdisciplinary research, to bring new investigators into the field, to develop programs of policy research, to answer next-step translational questions, and to enhance awareness of policy relevance. Success at meeting each of these goals is discussed. We offer recommendations for incorporating programs of policy research into full-spectrum transdisciplinary research initiatives, including the roles of research teams, senior researchers, infrastructure, stakeholders, and communications activities. The TTURC Partners initiative represented a first-generation effort to fill the gap between scientific discovery and research translation through expansion into policy studies. While all aspects of the effort were not equally successful, the effort demonstrated that it is possible to develop successful collaborations that extend more basic and applied research into studies that examine their policy and practice implications.

PULVERIZED COAL COMBUSTION: POLLUTANT FORMATION AND CONTROL, 1970-1980

EPA Science Inventory

The report documents the support role of EPA's Air and Energy Engineering Research Laboratory in the major research effort directed by EPA in the l970s to understand pollutant formation during pulverized coal combustion (PCC). Understanding the conversion of fuel nitrogen to nit...

Microgravity Science and Applications Program tasks, 1986 revision

NASA Technical Reports Server (NTRS)

1987-01-01

The Microgravity Science and Applications (MSA) program is directed toward research in the science and technology of processing materials under conditions of low gravity to provide a detailed examination of the constraints imposed by gravitational forces on Earth. The program is expected to lead to the development of new materials and processes in commercial applications adding to this nation's technological base. The research studies emphasize the selected materials and processes that will best elucidate the limitations due to gravity and demonstrate the enhanced sensitivity of control of processes that may be provided by the weightless environment of space. Primary effort is devoted to a study of the specific areas of research which reveals potential value in the initial investigations of the previous decades. Examples of previous process research include crystal growth and directional solidification of metals; containerless processing of reactive materials; synthesis and separation of biological materials; etc. Additional efforts will be devoted to identifying the special requirements which drive the design of hardware to reduce risk in future developments.

A project on groundwater research inventory and classification to make groundwater visible

NASA Astrophysics Data System (ADS)

Cseko, Adrienn; Petitta, Marco; van der Keur, Peter; Fernandez, Isabel; Garcia Alibrandi, Clint; Hinsby, Klaus; Hartai, Eva; Garcia Padilla, Mercedes; Szucs, Peter; Mikita, Viktoria; Bisevac, Vanja; Bodo, Balazs

2017-04-01

Hydrogeology related research activities cover a wide spectrum of research areas at EU and national levels. The European knowledge base on this important topic is widespread and fragmented into broader programs generally related to waterresources, environment or ecology. In order to achieve a comprehensive understanding on the groundwater theme, the KINDRA project (Knowledge Inventory for Hydrogeology Research - www.kindraproject.eu) seeks to carry out an accurate assessment of the state of the art in hydrogeology research and to create a critical mass for scientific knowledge exchange of hydrogeology research, to ensure wide accessibility and applicability of research results, including support of innovation and development, and to reduce unnecessary duplication of efforts. The first two years of the project have focused its efforts in developing the concept of a Harmonized Terminology and Methodology for Classification and Reporting Hydrogeology related Research in Europe (HRCSYS) as well as its implementation in the European Inventory of Groundwater Research (EIGR). For developing the common terminology, keywords characterizing research on groundwater have been identified from two main sources: the most important EU directives and policy documents and from groundwater related scientific literature. To assess the importance and pertinence of the keywords, these have been ranked by performing searches via the Web of Science, Scopus and Google Scholar search engines. The complete merged list of keywords consisting of more than 200 terms has been organized in a tree hierarchy, identifying three main categories: Societal Challenges (SC), Operational Actions (OA) and Research Topics (RT). The relationships among these main categories expressed by a 3D approach, identifying single intersections among 5 main overarching groups for each category. The EIGR itself contains metadata (about 1800 records at the moment) of research efforts and topic related knowledge deliverables (scientific reports, articles, projects, etc.) illustrating and providing links to research efforts carried out through Europe since 2000, indicating where data can be retrieved, and following their classification according to the proposed methodology. Both the HRC-SYS classification approach and the EIGR tool, are fundamental to achieve the main aim of the KINDRA project: to create an overview of the scientific knowledge covering European countries by means of an accurate assessment of hydrogeology research in various geographical and geo-environmental settings, and to allow for a direct comparison and exploit existing synergies. The scope of the project also includes identification of future trends, critical challenges and research gaps, to improve management and policy development for groundwater resources on a EU level coherently with the Water Framework Directive (WFD) and Groundwater Directive (GWD). As part of the work to be carried out in 2017, the identified research gaps will be converted into specific recommendations for the further development of EU level policies and research programmes. The project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 642047.

LIFE CYCLE IMPACT ASSESSMENT AN INTRODUCTION AND INTERNATIONAL UPDATE

EPA Science Inventory

Research within the field of Life Cycle Impact Assessment (LCIA) has greatly improved since the work of Heijungs and Guinee in 1992. Within the UNEP / SETAC Life Cycle Initiative an effort is underway to provide recommendations about the direction of research and selection of LC...

Institutional Research: The Key to Successful Enrollment Management.

ERIC Educational Resources Information Center

Clagett, Craig A.

Enrollment management includes the processes and activities that influence the size, shape, and characteristics of a student body by directing institutional efforts in marketing, recruitment, admissions, pricing, and financial aid. Institutional research plays an essential, if not the key, role in enrollment management. This report discusses the…

Redefining risk research priorities for nanomaterials

NASA Astrophysics Data System (ADS)

Grieger, Khara D.; Baun, Anders; Owen, Richard

2010-02-01

Chemical-based risk assessment underpins the current approach to responsible development of nanomaterials (NM). It is now recognised, however, that this process may take decades, leaving decision makers with little support in the near term. Despite this, current and near future research efforts are largely directed at establishing (eco)toxicological and exposure data for NM, and comparatively little research has been undertaken on tools or approaches that may facilitate near-term decisions, some of which we briefly outline in this analysis. We propose a reprioritisation of NM risk research efforts to redress this imbalance, including the development of more adaptive risk governance frameworks, alternative/complementary tools to risk assessment, and health and environment surveillance.

RIAD visual imaging branch assessment

NASA Technical Reports Server (NTRS)

Beam, Sherilee F.

1993-01-01

Every year the demand to visualize research efforts increases. The visualization provides the means to effectively analyze data and present the results. The technology support for visualization is constantly changing, improving, and being made available to users everywhere. As such, many researchers are entering into the practice of doing their own visualization in house - sometimes successfully, sometimes not. In an effort to keep pace with the visualization needs of researchers, the Visual Imaging Branch of the Research, Information, and Applications Division at NASA Langley Research Center has conducted an investigation into the current status of imaging technology and imaging production throughout the various research branches at the center. This investigation will allow the branch to evaluate its current resources and personnel in an effort to identify future directions for meeting the needs of the researchers at the center. The investigation team, which consisted of the ASEE fellow, the head of the video section, and the head of the photo section, developed an interview format that could be accomplished during a short interview period with researchers, and yet still provide adequate statistics about items such as in-house equipment and usage.

Foreign Language Anxiety as an Individual Difference Variable in Performance: From an Interactionist's Perspective.

ERIC Educational Resources Information Center

Kim, Youngsang

This article addresses a research direction in which language professionals' research efforts can be invested to clarify the conceptual framework of the foreign language (FL) anxiety construct and develop an alternative measure to the construct. Current research on the effects of FL anxiety on learner performance has yielded inconsistent research…

University Research and the City: A Report from the President of New York University.

ERIC Educational Resources Information Center

Hester, James M.

This report describes selected urban-oriented research projects of New York University that are designed to draw on the city's resources to develop new knowledge for the improvement of urban society. The university's efforts to solve urban problems take 2 forms: (1) research leadership, directed at identifying and analyzing major problems and…

Challenges for the Urban Community College. AACJC Issues Series No. 4.

ERIC Educational Resources Information Center

Stahl, Frederick E., Ed.

Using as its premise that access and excellence are mutually interdependent goals for urban community colleges, this monograph considers the direction and nature of programmatic responses to the needs of the constituencies of urban two-year colleges and the direction and quality of the research efforts required to measure institutional impact on…

Image-based ranging and guidance for rotorcraft

NASA Technical Reports Server (NTRS)

Menon, P. K. A.

1991-01-01

This report documents the research carried out under NASA Cooperative Agreement No. NCC2-575 during the period Oct. 1988 - Dec. 1991. Primary emphasis of this effort was on the development of vision based navigation methods for rotorcraft nap-of-the-earth flight regime. A family of field-based ranging algorithms were developed during this research period. These ranging schemes are capable of handling both stereo and motion image sequences, and permits both translational and rotational camera motion. The algorithms require minimal computational effort and appear to be implementable in real time. A series of papers were presented on these ranging schemes, some of which are included in this report. A small part of the research effort was expended on synthesizing a rotorcraft guidance law that directly uses the vision-based ranging data. This work is discussed in the last section.

Future directions in physical activity intervention research: expanding our focus to sedentary behaviors, technology, and dissemination.

PubMed

Lewis, Beth A; Napolitano, Melissa A; Buman, Matthew P; Williams, David M; Nigg, Claudio R

2017-02-01

Despite the increased health risks of a sedentary lifestyle, only 49 % of American adults participate in physical activity (PA) at the recommended levels. In an effort to move the PA field forward, we briefly review three emerging areas of PA intervention research. First, new intervention research has focused on not only increasing PA but also on decreasing sedentary behavior. Researchers should utilize randomized controlled trials, common terminology, investigate which behaviors should replace sedentary behaviors, evaluate long-term outcomes, and focus across the lifespan. Second, technology has contributed to an increase in sedentary behavior but has also led to innovative PA interventions. PA technology research should focus on large randomized trials with evidence-based components, explore social networking and innovative apps, improve PA monitoring, consider the lifespan, and be grounded in theory. Finally, in an effort to maximize public health impact, dissemination efforts should address the RE-AIM model, health disparities, and intervention costs.

Future directions in physical activity intervention research: expanding our focus to sedentary behaviors, technology, and dissemination

PubMed Central

Napolitano, Melissa A.; Buman, Matthew P.; Williams, David M.; Nigg, Claudio R.

2016-01-01

Despite the increased health risks of a sedentary lifestyle, only 49 % of American adults participate in physical activity (PA) at the recommended levels. In an effort to move the PA field forward, we briefly review three emerging areas of PA intervention research. First, new intervention research has focused on not only increasing PA but also on decreasing sedentary behavior. Researchers should utilize randomized controlled trials, common terminology, investigate which behaviors should replace sedentary behaviors, evaluate long-term outcomes, and focus across the lifespan. Second, technology has contributed to an increase in sedentary behavior but has also led to innovative PA interventions. PA technology research should focus on large randomized trials with evidence-based components, explore social networking and innovative apps, improve PA monitoring, consider the lifespan, and be grounded in theory. Finally, in an effort to maximize public health impact, dissemination efforts should address the RE-AIM model, health disparities, and intervention costs. PMID:27722907

Nutrition Education Research: Directions for the Future. [Proceedings].

ERIC Educational Resources Information Center

Brun, Judy K., Ed.

A Nutrition Education Research Conference was hosted by the National Dairy Council on December 4-6, 1978. Specific purposes of the conference were to: (1) examine historical foundations; (2) analyze governmental activities; (3) determine current status; and (4) identify priorities for future efforts. The conference's general sessions focused on…

Creating the Future: "New Directions" in American Research Universities

ERIC Educational Resources Information Center

Brint, Steven

2005-01-01

This paper assesses the causes and consequences of recent American efforts to configure the research university as an engine of economic and social change. Drawing upon interviews and strategic plans, the paper describes recent policies to encourage "interdisciplinary creativity," in a context of increasing income from private gifts and endowments.

Building a Successful Adult Life: Findings from Youth-Directed Research

ERIC Educational Resources Information Center

Powers, Laurie E.; Garner, Tracee; Valnes, Betsy; Squire, Peter; Turner, Alison; Couture, Todd; Dertinger, Rocky

2007-01-01

Although transition outcomes for youth with disabilities have shown some improvement and transition support practices have been identified, many young people continue to face transition barriers that preclude their full participation in key adult life activities. While research efforts have largely been professionally driven, there is emerging…

The Picture Superiority Effect and Biological Education.

ERIC Educational Resources Information Center

Reid, D. J.

1984-01-01

Discusses learning behaviors where the "picture superiority effect" (PSE) seems to be most effective in biology education. Also considers research methodology and suggests a new research model which allows a more direct examination of the strategies learners use when matching up picture and text in efforts to "understand"…

The Organized Contradictions of Professional Development and School Improvement

ERIC Educational Resources Information Center

Sappington, Neil; Pacha, Joseph; Baker, Paul; Gardner, Dianne

2012-01-01

"One of the most persistent findings from research on school improvement is, in fact, the symbiotic relationship between professional development and school improvement efforts" (Hawley & Valli, 1999, p. 129). These researchers, and others in the field, argue that there must be a direct relationship between the professional…

Expatriate Preparation: A Critical Analysis of 25 Years of Cross-Cultural Training Research

ERIC Educational Resources Information Center

Littrell, Lisa N.; Salas, Eduardo; Hess, Kathleen P.; Paley, Michael; Riedel, Sharon

2006-01-01

Although much research in the 1960s and 1970s was devoted to cross-cultural issues such as expatriate employment, researchers moved away from doing cross-cultural research in order to direct their efforts toward the hot topics of the time. However, the past few decades have seen an exponential increase in the globalization of our economy, and this…

Cue generation and memory construction in direct and generative autobiographical memory retrieval.

PubMed

Harris, Celia B; O'Connor, Akira R; Sutton, John

2015-05-01

Theories of autobiographical memory emphasise effortful, generative search processes in memory retrieval. However recent research suggests that memories are often retrieved directly, without effortful search. We investigated whether direct and generative retrieval differed in the characteristics of memories recalled, or only in terms of retrieval latency. Participants recalled autobiographical memories in response to cue words. For each memory, they reported whether it was retrieved directly or generatively, rated its visuo-spatial perspective, and judged its accompanying recollective experience. Our results indicated that direct retrieval was commonly reported and was faster than generative retrieval, replicating recent findings. The characteristics of directly retrieved memories differed from generatively retrieved memories: directly retrieved memories had higher field perspective ratings and lower observer perspective ratings. However, retrieval mode did not influence recollective experience. We discuss our findings in terms of cue generation and content construction, and the implication for reconstructive models of autobiographical memory. Copyright © 2015 Elsevier Inc. All rights reserved.

Information Presentation

NASA Technical Reports Server (NTRS)

Holden, K.L.; Boyer, J.L.; Sandor, A.; Thompson, S.G.; McCann, R.S.; Begault, D.R.; Adelstein, B.D.; Beutter, B.R.; Stone, L.S.

2009-01-01

The goal of the Information Presentation Directed Research Project (DRP) is to address design questions related to the presentation of information to the crew. The major areas of work, or subtasks, within this DRP are: 1) Displays, 2) Controls, 3) Electronic Procedures and Fault Management, and 4) Human Performance Modeling. This DRP is a collaborative effort between researchers at Johnson Space Center and Ames Research Center.

Scientific and technical services directed toward the development of planetary quarantine measures for automated spacecraft

NASA Technical Reports Server (NTRS)

1974-01-01

The work is reported, which was performed in the specific tasks of the Planetary Quarantine research program for developing parameter specifications of unmanned scientific missions to the planets. The effort was directed principally toward the advancement of the quarantine technology, applicable to all future missions to planets of biological interest. The emphasis of the research was on coordinated evaluation, analysis, documentation, and presentation of PQ requirements for flight projects such as Viking and Pioneer.

Life prediction and constitutive behavior

NASA Technical Reports Server (NTRS)

Halford, G. R.

1983-01-01

One of the primary drivers that prompted the initiation of the hot section technology (HOST) program was the recognized need for improved cyclic durability of costly hot section components. All too frequently, fatigue in one form or another was directly responsible for the less than desired durability, and prospects for the future weren't going to improve unless a significant effort was mounted to increase our knowledge and understanding of the elements governing cyclic crack initiation and propagation lifetime. Certainly one of the important factors is the ability to perform accurate structural stress-strain analyses on a routine basis to determine the magnitudes of the localized stresses and strains since it is these localized conditions that govern the initiation and crack growth processes. Developing the ability to more accurately predict crack initiation lifetimes and cyclic crack growth rates for the complex loading conditions found in turbine engine hot sections is of course the ultimate goal of the life prediction research efforts. It has been found convenient to divide the research efforts into those dealing with nominally isotropic and anisotropic alloys; the latter for application to directionally solidified and single crystal turbine blades.

Changing the Legacy of Divorce: Evidence from Prevention Programs and Future Directions.

ERIC Educational Resources Information Center

Haine, Rachel A.; Sandler, Irwin N.; Wolchik, Sharlene A.; Tein, Jenn-Yun; Dawson-McClure, Spring R.

2003-01-01

Assesses efforts to prevent mental health problems in children of divorce by highlighting the importance of using theory in the design and evaluation of prevention programs and by reviewing the empirical research on the efficacy of programs to improve outcomes for children of divorce. Also proposes two future directions for advancing theory-based…

Development of breeding populations of rhesus macaques (Macaca mulatta) that are specific pathogen-free for rhesus cytomegalovirus.

PubMed

Barry, Peter A; Strelow, Lisa

2008-02-01

Development of breeding colonies of rhesus macaques (Macaca mulatta) that are specific pathogen-free (SPF) for rhesus cytomegalovirus (RhCMV) is relatively straightforward and requires few modifications from current SPF programs. Infants separated from the dam at or within a few days of birth and cohoused with similarly treated animals remain RhCMV seronegative indefinitely, provided they are never directly or indirectly exposed to a RhCMV-infected monkey. By systematically cohousing seronegative animals into larger social cohorts, breeding populations of animals SPF for RhCMV can be established. The additional costs involved in expanding the current definition of SPF status to include RhCMV are incremental compared with the money already being spent on existing SPF efforts. Moreover, the large increase in research opportunities available for RhCMV-free animals arguably would far exceed the development costs. Potential new areas of research and further expansion of existing research efforts involving these newly defined SPF animals would have direct implications for improvements in human health.

The Monsoon-90 / SALSA / EOS / SUDMED / SAHRA / HELP / USPP Experience: A Progression of Interdisciplinary Integration of Science and Decision Making over 20 years.

NASA Astrophysics Data System (ADS)

Chehbouni, G.; Goodrich, D.; Kustas, B.; Sorooshian, S.; Shuttleworth, J.; Richter, H.

2008-12-01

The Monsoon'90 Experiment conducted at the USDA-ARS Walnut Gulch Experimental Watershed in southeast Arizona was the start of a long arc of subsequent experiments and research that were larger, longer-term, more international, more interdisciplinary, and led to more direct integration of science for decision making and watershed management. In this era, much of our research and science must be more directly relevant to decision-makers and natural resource managers as they increasingly require sophisticated levels of expert findings and scientific results (e.g. interdisciplinary) to make informed decisions. Significant effort beyond focused, single disciplinary research is required conduct interdisciplinary science typical in large scale field experiments. Even greater effort is required to effectively integrate our research across the physical and ecological sciences for direct use by policy and decision makers. This presentation will provide an overview of the evolution of this arc of experiments and long-term projects into a mature integrated science and decision making program. It will discuss the transition in project focus from science and research for understanding; through science for addressing a need; to integrated science and policy development. At each stage the research conducted became more interdisciplinary, first across abiotic disciplines (hydrology, remote sensing, atmospheric science), then by merging abiotic and biotic disciplines (adding ecology and plant physiology), and finally a further integration of economic and social sciences with and policy and decision making for resource management. Lessons learned from this experience will be reviewed with the intent providing guidance to ensure that the resulting research is socially and scientifically relevant and will not only result in cutting edge science but will also directly address the needs of policy makers and resource managers.

Space Technology: A study of the significance of recognition for innovators of spinoff technologies. A case study on the impact of the space technology hall of fame award

NASA Technical Reports Server (NTRS)

1993-01-01

This report represents the preliminary effort in studying the significance of recognition for innovators of spinoff technologies. The purpose of this initial year's effort in this area was to gather preliminary data and define the direction for the remainder of the research. This report focuses on the most recent recipients of the Hall of Fame Award, the developers of liquid-cooled garments. Liquid-cooled garments technology and its spinoffs were used as a case study to define and explore the factors involved in technology transfer and to consider the possible incentives in developing commercial applications including the Hall of Fame Award. Through interviews, views of award recipients were obtained on factors encouraging spinoffs as well as impediments to spinoffs. The researchers observed complex inter-relationships among the significant entities (government, individuals, large and small business), the importance of people, the importance of resource availability, and the significance of intrinsic motivation; drew preliminary conclusions pertaining to the direct and indirect influence of recognition like the Hall of Fame Award; and planned the direction for next year's follow-on research.

Environmental and High-Strain Rate effects on composites for engine applications

NASA Technical Reports Server (NTRS)

Chamis, C. C.; Smith, G. T.

1982-01-01

The Lewis Research Center is conducting a series of programs intended to investigate and develop the application of composite materials to structural components for turbojet engines. A significant part of that effort is directed to establishing resistance, defect growth, and strain rate characteristics of composite materials over the wide range of environmental and load conditions found in commercial turbojet engine operations. Both analytical and experimental efforts are involved.

Ethics, Education Policy and Research: The Phonics Question Reconsidered

ERIC Educational Resources Information Center

Ellis, Sue; Moss, Gemma

2014-01-01

This paper argues that direct control of the early years literacy curriculum recently exercised by politicians in England has made the boundaries between research, policy and practice increasingly fragile. It describes how policy came to focus most effort on the use of synthetic phonics programmes in the early years. It examines why the…

Promoting Positive Youth Development: Implications for Future Directions in Developmental Theory, Methods, and Research

ERIC Educational Resources Information Center

Kurtines, William M.; Montgomery, Marilyn J.; Ferrer-Wreder, Laura; Berman, Steven L.; Lorente, Carolyn Cass; Silverman, Wendy K.

2008-01-01

The efforts of the Miami Youth Development Project reported in this special issue illustrate how Developmental Intervention Science (DIS; a fusion of the developmental and intervention science) extended to include outreach research contributes to the development of community-supported positive youth development programs. In the process, the…

The Role of Job Challenge and Organizational Identification in Enhancing Creative Behavior among Employees in the Workplace

ERIC Educational Resources Information Center

Carmeli, Abraham; Cohen-Meitar, Ravit; Elizur, Dov

2007-01-01

Organizations recognize the importance of creative employees and constantly explore ways to enhance their employees' creative behavior. Creativity research has directed substantial efforts to understanding how work environment fosters creativity. Yet, this research has paid little attention to the importance of specific characteristics of the work…

Intellectual Disabilities and Mental Health: United States-Based Research

ERIC Educational Resources Information Center

Charlot, Lauren; Beasley, Joan B.

2013-01-01

In the United States, research directed specifically at improving our understanding of the psychiatric assessment and treatment of individuals with intellectual disabilities (ID) has grown, yet lags far behind efforts for typically developing children and adults. In the United States, a lack of a national approach to the mental health problems of…

Narratives of Community Educators Fostering Adult Education and Community Development

ERIC Educational Resources Information Center

Delgado, Perla Guadalupe

2017-01-01

This qualitative research reports on the narratives of six community educators and utilizes anatomy of story as a framework. The research question directing this study was: What can we learn from the journeys and trajectories of community educators? Supporting sub-questions included: (1) what are their efforts fostering adult education? and (2)…

New Opportunities and Directions in Home Visiting Research and Evaluation

ERIC Educational Resources Information Center

Supplee, Lauren H.; Harwood, Robin L.; Margie, Nancy Geyelin; Meyer, Aleta L.

2013-01-01

The authors describe the research and evaluation activities connected to the new Maternal, Infant and Early Childhood Home Visiting program. The goal of these activities is to provide information on federal, state, and local efforts to strengthen programs by providing much needed knowledge on the best ways to support the implementation of home…

Increased Attention to Human Sexuality Can Improve HIV-AIDS Prevention Efforts: Key Research Issues and Directions.

ERIC Educational Resources Information Center

Kelly, Jeffrey A.; Kalichman, Seth C.

1995-01-01

Discusses curtailing the human immunodeficiency virus (HIV) by helping people reduce high-risk sexual behavior. Reviews research in the relationship contexts of sexuality, including variations in monogamy, condom use in affectionate versus casual relationships, sexual communication, and coercion. Notes policy and training issues related to human…

ECN-15662

NASA Image and Video Library

1981-05-21

The Dryden C-140 JetStar during testing of advanced propfan designs. Dryden conducted flight research in 1981-1982 on several designs. The technology was developed under the direction of the Lewis Research Center (today the Glenn Research Center, Cleveland, OH) under the Advanced Turboprop Program. Under that program, Langley Research Center in Virginia oversaw work on accoustics and noise reduction. These efforts were intended to develop a high-speed and fuel-efficient turboprop system.

Research on enhancing the utilization of digital multispectral data and geographic information systems in global habitability studies

NASA Technical Reports Server (NTRS)

Martinko, Edward A.; Merchant, James W.

1988-01-01

During 1986 to 1987, the Kansas Applied Remote Sensing (KARS) Program continued to build upon long-term research efforts oriented towards enhancement and development of technologies for using remote sensing in the inventory and evaluation of land use and renewable resources (both natural and agricultural). These research efforts directly addressed needs and objectives of NASA's Land-Related Global Habitability Program as well as needs of and interests of public agencies and private firms. The KARS Program placed particular emphasis on two major areas: development of intelligent algorithms to improve automated classification of digital multispectral data; and integrating and merging digital multispectral data with ancillary data in spatial modes.

Computing Cluster for Large Scale Turbulence Simulations and Applications in Computational Aeroacoustics

NASA Astrophysics Data System (ADS)

Lele, Sanjiva K.

2002-08-01

Funds were received in April 2001 under the Department of Defense DURIP program for construction of a 48 processor high performance computing cluster. This report details the hardware which was purchased and how it has been used to enable and enhance research activities directly supported by, and of interest to, the Air Force Office of Scientific Research and the Department of Defense. The report is divided into two major sections. The first section after this summary describes the computer cluster, its setup, and some cluster performance benchmark results. The second section explains ongoing research efforts which have benefited from the cluster hardware, and presents highlights of those efforts since installation of the cluster.

Proceedings of the 1988 International Meeting on Reduced Enrichment for Research and Test Reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-07-01

The international effort to develop and implement new research reactor fuels utilizing low-enriched uranium, instead of highly- enriched uranium, continues to make solid progress. This effort is the cornerstone of a widely shared policy aimed at reducing, and possibly eliminating, international traffic in highly-enriched uranium and the nuclear weapon proliferation concerns associated with this traffic. To foster direct communication and exchange of ideas among the specialists in this area, the Reduced Enrichment Research and Test Reactor (RERTR) Program, at Argonne National Laboratory, sponsored this meeting as the eleventh of a series which began 1978. Individual papers presented at the meetingmore » have been cataloged separately.« less

Paradigms for investigating rehabilitation and adaptation to childhood disability and chronic illness.

PubMed

Harper, D C

1991-10-01

Significant research perspectives in investigating chronic illness and disability are presented. Historical research conceptualizations in childhood disability are reviewed and newer contexts for evaluating disorder are presented. Future research in childhood illness and disability is directed toward basing investigations on theoretical models and promoting prospective longitudinal programs. Pediatric psychologists are encouraged to consider more collaborative efforts to move the field forward systematically.

An Industry Picture of U. S. Science Policy.

ERIC Educational Resources Information Center

David, Edward E., Jr.

1986-01-01

Offers perspectives on the status and direction of federal science policy. Assesses current efforts dealing with megaprojects, basic research, and cooperative projects. Provides suggestions for improving federal science policy so as to better promote industrial competitiveness. (ML)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldstein, L.; Hedman, B.; Knowles, D.

The U. S. Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) is directing substantial programs in the development and encouragement of new energy technologies. Among them are renewable energy and distributed energy resource technologies. As part of its ongoing effort to document the status and potential of these technologies, DOE EERE directed the National Renewable Energy Laboratory to lead an effort to develop and publish Distributed Energy Technology Characterizations (TCs) that would provide both the department and energy community with a consistent and objective set of cost and performance data in prospective electric-power generation applications inmore » the United States. Toward that goal, DOE/EERE - joined by the Electric Power Research Institute (EPRI) - published the Renewable Energy Technology Characterizations in December 1997.As a follow-up, DOE EERE - joined by the Gas Research Institute - is now publishing this document, Gas-Fired Distributed Energy Resource Technology Characterizations.« less

Botulinum neurotoxin vaccines: Past history and recent developments.

PubMed

Rusnak, Janice M; Smith, Leonard A

2009-12-01

Botulinum toxin may cause a neuroparalytic illness that may result in respiratory failure and require prolonged mechanical ventilation. As medical resources needed for supportive care of botulism in a bioterrorist event may quickly overwhelm the local healthcare systems, biodefense research efforts have been directed towards the development of a vaccine to prevent botulism. While human botulism has been caused only by toxin serotypes A, B, and E (rarely serotype F), all seven known immunologically distinct toxin serotypes (A - G) may potentially cause intoxication in humans from a bioterrorist event. A pentavalent (ABCDE) botulinum toxoid (PBT) has been administered as an investigation new drug (IND) to at-risk individuals for nearly 50 years. Due to declining immunogenicity of the PBT, research efforts have been directed at development of both improved (less local reactogenicity) botulinum toxoids and recombinant vaccines as potential vaccine candidates to replace the PBT.

Leadership Characteristics 1900-1982.

DTIC Science & Technology

1983-04-01

complex of factors associated with leadership status (Bass 1981), the entertainment of this premise by comtemporary researchers is viewed as unreliable...to direct their total energies in the formulation of a small business rather than support the missions of tradi- tional corporate or military...effort is directed toward the development and man- agement of personal sideline businesses . They eventually succeed in turning part-time sidelines

NASA Workshop on Biological Adaptation

NASA Technical Reports Server (NTRS)

Morey-Holton, Emily (Editor); Tischler, Marc (Editor)

1988-01-01

A workshop was convened to review the current program in Space Biology Biological Adaptation Research and its objectives and to identify future research directions. Two research areas emerged from these deliberations: gravitational effects on structures and biomineralization and gravity affected regulatory mechanisms. The participants also recommended that research concentrate on rapidly growing animals, since gravity effects may be more pronounced during growth and development. Both research areas were defined and future research directions were identified. The recommendations of the workshop will assist the Life Sciences Division of NASA in it assessment and long-range planning of these areas of space biology. Equally important, the workshop was intended to stimulate thought and research among those attending so that they would, in turn, interest, excite, and involve other members of the academic community in research efforts relevant to these programs.

TravelingGeologist: an online platform for dissemination of earth science to the masses

NASA Astrophysics Data System (ADS)

Spencer, C. J.; Hoiland, C. W.; Gunderson, K. L.

2016-12-01

To more effectively inspire the next generation of scientists, the earth science community's public outreach efforts must adapt to the changing technological and informational ecosystems in which young people interact online (e.g. blogs, social media, viral marketing, web-based education, etc.). Although there are currently a number of successful individual and institutional efforts to reach potential students through web-based outlets, many of these efforts fail to connect primary researchers directly to a lay audience, relying instead on intermediaries that tend to dilute the recruiting impact of "producer-to-consumer" interactions. Few, if any of these efforts appear to have reached a critical mass of contributing authors and subscribed followers; and there are few available detailed metrics on growth trajectories, impact, or lay reach. We offer data from the TravelingGeologist as a case study in successful direct-to-consumer science outreach and recruitment. The TravelingGeologist is a non-profit, web-based platform on which earth scientists share their experiences in the field with the expressed purpose of attracting and inspiring a new generation of scientists. The TravelingGeologist website is supplemented by various social media platforms that market the content on the main site. Because TravelingGeologist accepts contributions from a variety of earth scientists, it also provides an arena whereon research summaries and vignettes can be shared with the large lay- and expert audience. This gives contributing authors an additional opportunity to demonstrate to government institutions that fund their research projects that they are engaging in efforts to communicate their results to the wider public. Beyond the ability to inspire new students and communicate science to the general public, it is our intent that TravelingGeologist will foster communication and promote collaboration within the earth science community. We have demonstrated that through well-designed web-based media in a wide array of social media markets, earth scientists can disseminate their research to the public and inspire the next generation of earth scientists.

The origin, fate, and health effects of combustion by-products: a research framework.

PubMed

Avakian, Maureen D; Dellinger, Barry; Fiedler, Heidelore; Gullet, Brian; Koshland, Catherine; Marklund, Stellan; Oberdörster, Günter; Safe, Stephen; Sarofim, Adel; Smith, Kirk R; Schwartz, David; Suk, William A

2002-11-01

Incomplete combustion processes can emit organic pollutants, metals, and fine particles. Combustion by-products represent global human and environmental health challenges that are relevant not only in heavily industrialized nations, but also in developing nations where up to 90% of rural households rely on unprocessed biomass fuels for cooking, warmth, and light. These issues were addressed at the Seventh International Congress on Combustion By-Products, which convened 4-6 June 2001 in Research Triangle Park, North Carolina. This congress included a diverse group of multidisciplinary researchers and practitioners who discussed recent developments and future goals in the control of combustion by-products and their effects of exposure on human and ecologic health. Participants recommended that interdisciplinary, coordinated research efforts should be focused to capitalize on the important potential synergisms between efforts to reduce the adverse human health effects linked to exposures to combustion by-products and broader efforts to reduce greenhouse gas emissions and save energy through efficiency. In this article we summarize the principal findings and recommendations for research focus and direction.

The origin, fate, and health effects of combustion by-products: a research framework.

PubMed Central

Avakian, Maureen D; Dellinger, Barry; Fiedler, Heidelore; Gullet, Brian; Koshland, Catherine; Marklund, Stellan; Oberdörster, Günter; Safe, Stephen; Sarofim, Adel; Smith, Kirk R; Schwartz, David; Suk, William A

2002-01-01

Incomplete combustion processes can emit organic pollutants, metals, and fine particles. Combustion by-products represent global human and environmental health challenges that are relevant not only in heavily industrialized nations, but also in developing nations where up to 90% of rural households rely on unprocessed biomass fuels for cooking, warmth, and light. These issues were addressed at the Seventh International Congress on Combustion By-Products, which convened 4-6 June 2001 in Research Triangle Park, North Carolina. This congress included a diverse group of multidisciplinary researchers and practitioners who discussed recent developments and future goals in the control of combustion by-products and their effects of exposure on human and ecologic health. Participants recommended that interdisciplinary, coordinated research efforts should be focused to capitalize on the important potential synergisms between efforts to reduce the adverse human health effects linked to exposures to combustion by-products and broader efforts to reduce greenhouse gas emissions and save energy through efficiency. In this article we summarize the principal findings and recommendations for research focus and direction. PMID:12417488

Evaluation of the application of ERTS-1 data to the regional land use planning process. [Wisconsin

NASA Technical Reports Server (NTRS)

Clapp, J. L. (Principal Investigator)

1974-01-01

The author has identified the following significant results. Investigators have concentrated on efforts toward assessing the achievements of the current ERTS-1 research so that significant results could be incorporated into the updated version of their ERTS-B research proposal. Significant progress was made in the development of operational mechanisms, linking the research community at the University and the operation agencies of the State of Wisconsin. Efforts have been made to finalize a report which is being prepared for the State of Wisconsin Department of Administration, evaluating the applicability of ERTS-1 to the planning needs of the State of Wisconsin. This document is intended to assess the degree of utility of the satellite for providing information which has been designated by state planners as essential to their needs. This effort is considered highly significant to the overall research program since a situation has been created in which a prime potential user of ERTS type data has been given the opportunity to determine the direction of the research.

Research impact in the community-based health sciences: an analysis of 162 case studies from the 2014 UK Research Excellence Framework.

PubMed

Greenhalgh, Trisha; Fahy, Nick

2015-09-21

The 2014 UK Research Excellence Framework (REF2014) generated a unique database of impact case studies, each describing a body of research and impact beyond academia. We sought to explore the nature and mechanism of impact in a sample of these. The study design was manual content analysis of a large sample of impact case studies (producing mainly quantitative data), plus in-depth interpretive analysis of a smaller sub-sample (for qualitative detail), thereby generating both breadth and depth. For all 162 impact case studies submitted to sub-panel A2 in REF2014, we extracted data on study design(s), stated impacts and audiences, mechanisms of impact, and efforts to achieve impact. We analysed four case studies (selected as exemplars of the range of approaches to impact) in depth, including contacting the authors for their narratives of impact efforts. Most impact case studies described quantitative research (most commonly, trials) and depicted a direct, linear link between research and impact. Research was said to have influenced a guideline in 122 case studies, changed policy in 88, changed practice in 84, improved morbidity in 44 and reduced mortality in 25. Qualitative and participatory research designs were rare, and only one case study described a co-production model of impact. Eighty-two case studies described strong and ongoing linkages with policymakers, but only 38 described targeted knowledge translation activities. In 40 case studies, no active efforts to achieve impact were described. Models of good implementation practice were characterised by an ethical commitment by researchers, strong institutional support and a proactive, interdisciplinary approach to impact activities. REF2014 both inspired and documented significant efforts by UK researchers to achieve impact. But in contrast with the published evidence on research impact (which depicts much as occurring indirectly through non-linear mechanisms), this sub-panel seems to have captured mainly direct and relatively short-term impacts one step removed from patient outcomes. Limited impacts on morbidity and mortality, and researchers' relatively low emphasis on the processes and interactions through which indirect impacts may occur, are concerns. These findings have implications for multi-stakeholder research collaborations such as UK National Institute for Health Research Collaborations for Leadership in Applied Health Research and Care, which are built on non-linear models of impact.

Information Presentation: Human Research Program - Space Human Factors and Habitability, Space Human Factors Engineering Project

NASA Technical Reports Server (NTRS)

Holden, Kristina L.; Sandor, Aniko; Thompson, Shelby G.; Kaiser, Mary K.; McCann, Robert S.; Begault, D. R.; Adelstein, B. D.; Beutter, B. R.; Wenzel, E. M.; Godfroy, M.;

Summaries of BFRL fire research in-house projects and grants, 1993

NASA Astrophysics Data System (ADS)

Jason, Nora H.

1993-09-01

The report describes the fire research projects performed in the Building and Fire Research Laboratory (BFRL) and under its extramural grants program during fiscal year 1993. The BFRL Fire Research Program has directed its efforts under three program thrusts. The in-house priority projects, grants, and externally-funded efforts thus form an integrated, focussed ensemble. The publication is organized along those lines: fire risk and hazard prediction - carbon monoxide prediction, turbulent combustion, soot, engineering analysis, fire hazard assessment, and large fires; fire safety of products and materials - materials combustion, furniture flammability, and wall and ceiling fires; and advanced technologies for fire sensing and control - fire detection and fire suppression. For the convenience of the reader, an alphabetical listing of all grants is contained in Part 2.0.

Benefits Awareness: Educating Industry, Finance, and the Public About Space Commercialization

NASA Technical Reports Server (NTRS)

Powers, Blake; Nall, Mark; Casas, Joseph C.; Henderson, Robin N. (Technical Monitor)

2002-01-01

For space to be truly commercialized, businesses of all sizes and types must be involved, from foundries to agricultural research initiatives. Achieving this goal, however, requires three separate but integrated educational efforts to support it. The first is to educate industry leaders about the possibilities available through such research, while dispelling some of the myths and misinformation educate the financial community about the economic benefits that result both from the research and the leveraging of private research dollars through the use of space and microgravity research. The third is to educate the public about the tangible benefits that come directly to them from such efforts, the economic benefits to national economies from same, and the other less tangible benefits that will cascade from commercial operations. Together, these steps will educate and provide the framework necessary to help advance space commercialization.

Lessons learned from research and surveillance directed at highly pathogenic influenza A viruses in wild birds inhabiting North America

USDA-ARS?s Scientific Manuscript database

Following detections of highly pathogenic (HP) influenza A viruses (IAVs) in wild birds inhabiting East Asia after the turn of the millennium, the intensity of sampling of wild birds for IAVs increased throughout much of North America and the objectives for many research and surveillance efforts wer...

75 FR 55728 - Withdrawal of Proposed Rules; Discontinuing Rulemaking Efforts Listed in the Unified Agenda of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-14

... section 4 of TSCA was to support ATSDR's Substance Specific Applied Research Program, a program [email protected] . SUPPLEMENTARY INFORMATION: I. Does this Action Apply to Me? This action is directed to the... Office of Air and Radiation (OAR), along with EPA's Office of Research and Development (ORD), referred...

Understanding Context in a Diabetes-Related Healthy Eating Initiative in Rural America

ERIC Educational Resources Information Center

Faul, Anna C.

2014-01-01

The Institute on Aging and Social Work (the institute) supported directed efforts to enhance the research capacity of academics in gerontology across the nation. Due to my participation in the institute, I received intensive training in aging research from distinguished professors as well as staff from the National Institutes of Health (NIH). As a…

Students as Researchers of Culture and Language in Their Own Communities. Language & Social Processes [Series].

ERIC Educational Resources Information Center

Egan-Robertson, Ann, Ed.; Bloome, David, Ed.

This book presents new directions in classroom education generated by using ethnography and sociolinguistics as teaching tools, the theory behind these efforts, and the classroom practices involved. The chapters are organized to highlight three issues of recent concern to K-12 educators: how student ethnographic and sociolinguistic research can be…

Developing Initiatives for Home-Based Child Care: Current Research and Future Directions

ERIC Educational Resources Information Center

Porter, Toni; Paulsell, Diane

2011-01-01

Home-based child care accounts for a significant share of the child care supply in the United States, especially for infants and toddlers. A synthesis of the home-based care research literature and information about recent home-based care quality initiatives points to a critical need for more systematic efforts to develop and test quality…

Effect of social influence on effort-allocation for monetary rewards.

PubMed

Gilman, Jodi M; Treadway, Michael T; Curran, Max T; Calderon, Vanessa; Evins, A Eden

2015-01-01

Though decades of research have shown that people are highly influenced by peers, few studies have directly assessed how the value of social conformity is weighed against other types of costs and benefits. Using an effort-based decision-making paradigm with a novel social influence manipulation, we measured how social influence affected individuals' decisions to allocate effort for monetary rewards during trials with either high or low probability of receiving a reward. We found that information about the effort-allocation of peers modulated participant choices, specifically during conditions of low probability of obtaining a reward. This suggests that peer influence affects effort-based choices to obtain rewards especially under conditions of risk. This study provides evidence that people value social conformity in addition to other costs and benefits when allocating effort, and suggests that neuroeconomic studies that assess trade-offs between effort and reward should consider social environment as a factor that can influence decision-making.

A comprehensive review on the quasi-induced exposure technique.

PubMed

Jiang, Xinguo; Lyles, Richard W; Guo, Runhua

2014-04-01

The goal is to comprehensively examine the state-of-the-art applications and methodological development of quasi-induced exposure and consequently pinpoint the future research directions in terms of implementation guidelines, limitations, and validity tests. The paper conducts a comprehensive review on approximately 45 published papers relevant to quasi-induced exposure regarding four key topics of interest: applications, responsibility assignment, validation of assumptions, and methodological development. Specific findings include that: (1) there is no systematic data screening procedure in place and how the eliminated crash data will impact the responsibility assignment is generally unknown; (2) there is a lack of necessary efforts to assess the validity of assumptions prior to its application and the validation efforts are mostly restricted to the aggregated levels due to the limited availability of exposure truth; and (3) there is a deficiency of quantitative analyses to evaluate the magnitude and directions of bias as a result of injury risks and crash avoidance ability. The paper points out the future research directions and insights in terms of the validity tests and implementation guidelines. Copyright © 2013 Elsevier Ltd. All rights reserved.

A case for clean conferences in gambling research.

PubMed

Livingstone, Charles

2018-02-14

Gambling research is characterised by widespread gambling industry involvement. It is likely (as with alcohol and tobacco industry influence) that this will delay or divert effective harm prevention or minimisation measures. Gambling harms are known to be significant and widespread. Effective action to reduce these harms requires concomitant efforts to eliminate industry influence. Gambling industry influence and activity in three research forums is described. The influence of tobacco and alcohol industry involvement in research directions and outcomes is discussed. Aspects of the discursive elements of industry funded and/or directed research outputs are analysed in the context of industry-friendly discourse and its effects. Industry activity and participation at representative research forums is outlined. The examples and background provided demonstrate that specific material and discursive effects of gambling industry involvement can be discerned in the gambling literature. The consequences of this for the gambling evidence base around harm prevention and minimisation are presented. Industry influence operates at multiple levels within the gambling research field. There is increasing awareness of this, and of the effects it may have on the development and deployment of effective harm prevention and minimisation efforts. Key reforms are proposed: (i) the elimination of industry participation and sponsorship of gambling research associations and forums; and (ii) the establishment where necessary of new research forums and international scholarly associations. © 2018 Australasian Professional Society on Alcohol and other Drugs.

Demographic processes limiting seedling recruitment in arid grassland restoration

Treesearch

Jeremy J. James; Tony J. Svejcar; Matthew J. Rinella

2011-01-01

Seeding is an important management tool in aridland restoration, but seeded species often fail to establish. Previous research has largely focused on the technical aspects of seeding with little effort directed at identifying demographic processes driving recruitment failures.

Chemistry Teaching: Science or Alchemy?

ERIC Educational Resources Information Center

Johnstone, A. H.

1997-01-01

Suggests that the development of good chemistry teaching and the pursuit of research have essentially the same structure. Similarities include the need for a clear focus, efficiency in time and effort, and a direction that is more often right than wrong. (DDR)

UAS Integration in the NAS FY15 Annual Review

NASA Technical Reports Server (NTRS)

Grindle, Laurie; Randall, Debra; Hackenburg, Davis

2015-01-01

This presentation gives insight into the research activities and efforts being executed in order to integrate unmanned aircraft systems into the national airspace system. This briefing is to inform others of the UAS-NAS progress and future directions.

Parallel aeroelastic computations for wing and wing-body configurations

NASA Technical Reports Server (NTRS)

Byun, Chansup

1994-01-01

The objective of this research is to develop computationally efficient methods for solving fluid-structural interaction problems by directly coupling finite difference Euler/Navier-Stokes equations for fluids and finite element dynamics equations for structures on parallel computers. This capability will significantly impact many aerospace projects of national importance such as Advanced Subsonic Civil Transport (ASCT), where the structural stability margin becomes very critical at the transonic region. This research effort will have direct impact on the High Performance Computing and Communication (HPCC) Program of NASA in the area of parallel computing.

Space Electrochemical Research and Technology (SERT), 1989

NASA Technical Reports Server (NTRS)

Baldwin, Richard S. (Editor)

1989-01-01

The proceedings of NASA's second Space Electrochemical Research and Technology Conference are presented. The objectives of the conference were to examine current technologies, research efforts, and advanced ideas, and to identify technical barriers which affect the advancement of electrochemical energy storage systems for space applications. The conference provided a forum for the exchange of ideas and opinions of those actively involved in the field, with the intention of coalescing views and findings into conclusions on progress in the field, prospects for future advances, areas overlooked, and the directions of future efforts. Related overviews were presented in the areas of NASA advanced mission models. Papers were presented and workshops conducted in four technical areas: advanced concepts, hydrogen-oxygen fuel cells and electrolyzers, the nickel electrode, and advanced rechargable batteries.

Regulatory Considerations for the Clinical and Research Use of Transcranial Direct Current Stimulation (tDCS): review and recommendations from an expert panel

PubMed Central

Fregni, F; Nitsche, MA; Loo, C.K.; Brunoni, AR; Marangolo, P; Leite, J; Carvalho, S; Bolognini, N; Caumo, W; Paik, NJ; Simis, M; Ueda, K; Ekhitari, H; Luu, P; Tucker, DM; Tyler, WJ; Brunelin, J; Datta, A; Juan, CH; Venkatasubramanian, G; Boggio, PS; Bikson, M

2014-01-01

The field of transcranial electrical stimulation (tES) has experienced significant growth in the past 15 years. One of the tES techniques leading this increased interest is transcranial direct current stimulation (tDCS). Significant research efforts have been devoted to determining the clinical potential of tDCS in humans. Despite the promising results obtained with tDCS in basic and clinical neuroscience, further progress has been impeded by a lack of clarity on international regulatory pathways. We therefore convened a group of research and clinician experts on tDCS to review the research and clinical use of tDCS. In this report, we review the regulatory status of tDCS, and we summarize the results according to research, off-label and compassionate use of tDCS in the following countries: Australia, Brazil, France, Germany, India, Iran, Italy, Portugal, South Korea, Taiwan and United States. Research use, off label treatment and compassionate use of tDCS are employed in most of the countries reviewed in this study. It is critical that a global or local effort is organized to pursue definite evidence to either approve and regulate or restrict the use of tDCS in clinical practice on the basis of adequate randomized controlled treatment trials. PMID:25983531

Prediction of forces and moments for flight vehicle control effectors: Workplan

NASA Technical Reports Server (NTRS)

Maughmer, Mark D.

1989-01-01

Two research activities directed at hypersonic vehicle configurations are currently underway. The first involves the validation of a number of classical local surface inclination methods commonly employed in preliminary design studies of hypersonic flight vehicles. Unlike studies aimed at validating such methods for predicting overall vehicle aerodynamics, this effort emphasizes validating the prediction of forces and moments for flight control studies. Specifically, several vehicle configurations for which experimental or flight-test data are available are being examined. By comparing the theoretical predictions with these data, the strengths and weaknesses of the local surface inclination methods can be ascertained and possible improvements suggested. The second research effort, of significance to control during take-off and landing of most proposed hypersonic vehicle configurations, is aimed at determining the change due to ground effect in control effectiveness of highly swept delta planforms. Central to this research is the development of a vortex-lattice computer program which incorporates an unforced trailing vortex sheet and an image ground plane. With this program, the change in pitching moment of the basic vehicle due to ground proximity, and whether or not there is sufficient control power available to trim, can be determined. In addition to the current work, two different research directions are suggested for future study. The first is aimed at developing an interactive computer program to assist the flight controls engineer in determining the forces and moments generated by different types of control effectors that might be used on hypersonic vehicles. The first phase of this work would deal in the subsonic portion of the flight envelope, while later efforts would explore the supersonic/hypersonic flight regimes. The second proposed research direction would explore methods for determining the aerodynamic trim drag of a generic hypersonic flight vehicle and ways in which it can be minimized through vehicle design and trajectory optimization.

National Directions in Education Research Planning. A Conference Co-Sponsored by the National Educational Research Policy and Priorities Board and the Office of Educational Research and Improvement, U.S. Department of Education (McLean, Virginia, June 17-18, 1998). Report on the Conference.

ERIC Educational Resources Information Center

Timpane, Michael

A conference was convened to bring together representatives of educational research planning efforts underway in federal agencies and professional and scientific organizations. This report identifies the principal emphases and tentative agreements from the sessions. The clear sense of the conference was that the educational research system has…

Engineering education research: Impacts of an international network of female engineers on the persistence of Liberian undergraduate women studying engineering

NASA Astrophysics Data System (ADS)

Rimer, Sara; Reddivari, Sahithya; Cotel, Aline

2015-11-01

As international efforts to educate and empower women continue to rise, engineering educators are in a unique position to be a part of these efforts by encouraging and supporting women across the world at the university level through STEM education and outreach. For the past two years, the University of Michigan has been a part of a grassroots effort to encourage and support the persistence of engineering female students at University of Liberia. This effort has led to the implementation of a leadership camp this past August for Liberian engineering undergraduate women, meant to: (i) to empower engineering students with the skills, support, and inspiration necessary to become successful and well-rounded engineering professionals in a global engineering market; and (ii) to strengthen the community of Liberian female engineers by building cross-cultural partnerships among students resulting in a international network of women engineers. This session will present qualitative research findings on the impact of this grassroots effort on Liberian female students? persistence in engineering, and the future directions of this work.

Renewing U.S. Mathematics; Critical Resource for the Future.

DTIC Science & Technology

1986-04-30

developed tell us how to get a good estimate of the appropriate levels. Table 10 contains the numbers, which total $180 million per year. 38 Since FY...direct costs speaks for itself. Scientists in other fields would look at these numbers and ask how on earth research was getting done. Who was paying...mathematics funding are making an effort to redress the problem. However, recent budget constraints severely threaten their efforts. The issue is how to reach

Processing and plating helical metallic coils

NASA Technical Reports Server (NTRS)

1972-01-01

The results of research efforts to develop an optimized nickel cobalt coating suitable as a recording medium are outlined. The coating is to be used directly on a BeCu helical coil substrate of a helical coil NASA recorder. Specifically, efforts were made to: optimize the coating thickness; establish processes and techniques adaptable for the production of finalized plated helical coils; design and fabricate the equipment required for production and testing of the coils; and deliver finalized helical coils to NASA.

Establishing effective working relations with a potential user community - NASA Lewis Research Center experience

NASA Technical Reports Server (NTRS)

Foster, P.

1977-01-01

The NASA Lewis Research Center has held a series of six major and unique technology utilization conferences which were major milestones in planned structured efforts to establish effective working relationships with specific technology user communities. These efforts were unique in that the activities undertaken prior to the conference were extensive, and effectively laid the groundwork for productive technology transfer following, and as a direct result of, the conferences. The effort leading to the conference was in each case tailored to the characteristics of the potential user community, however, the common factors comprise a basic framework applicable to similar endeavors. The process is essentially a planned sequence of steps that constitute a technical market survey and a marketing program for the development of beneficial applications of aerospace technology beyond the aerospace field.

Systematics of Fusaria associated with Ambrosia beetles

USDA-ARS?s Scientific Manuscript database

Here, I summarize research efforts directed at characterizing ambrosia beetle-associated fusaria, including the species responsible for avocado wilt in Israel (Mendel et al., Phytoparasitica 2012) and branch dieback in California (Eskalen et al., Pl. Dis. 2012). Our multilocus molecular phylogenetic...

Learning through Making and Maker Education

ERIC Educational Resources Information Center

Hsu, Yu-Chang; Baldwin, Sally; Ching, Yu-Hui

2017-01-01

In this paper, we provide an overview of the current efforts in maker education, supported by a review of empirical studies. Our synthesis will inform the community about learning outcomes, potential and common issues, challenges, resources, and future research direction regarding maker education.

Career Counseling with Lesbian, Gay, Bisexual, and Transgendered Persons: The Next Decade.

ERIC Educational Resources Information Center

Chung, Y. Barry

2003-01-01

Proposes future directions for career counseling with lesbian, gay male, bisexual male and female, and transgendered persons. Suggestions include efforts for theory development, empirical research, career assessment, counseling practice, and counselor education. (Contains 53 references.) (GCP)

UAS Integration in the NAS Project - FY 14 Annual Review

NASA Technical Reports Server (NTRS)

Grindle, Laurie; Randall, Debra; Hackenberg, Davis

2014-01-01

This briefing gives insight into the research activities and efforts being executed in order to integrate unmanned aircraft systems into the national airspace system. This briefing is to inform others of the UAS-NAS Projects progress and future directions.

Laboratory Directed Research and Development Program FY2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

none, none

2012-04-27

Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2011 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). Going forward in FY 2012, the LDRD program also supports themore » Goals codified in the new DOE Strategic Plan of May, 2011. The LDRD program also supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and review by the Office of Science Program Offices, such as LDRD projects germane to new research facility concepts and new fundamental science directions. Brief summares of projects and accomplishments for the period for each division are included.« less

A desk review on institutional and non-institutional organizations active in the field of migrant's health in the WHO European Region.

PubMed

Ingrosso, Loredana; Schmidt, Tanja; Sherally, Jamila; Dembech, Matteo; Barragan Montes, Sara; Sa Machado, Rita; Annunziata, Giuseppe; Rezza, Giovanni; Severoni, Santino

2015-01-01

Migrants have problematic access to health-care; non-institutional organizations (NGOs), as well as institutional bodies may play a role in facilitating their access to mainstream health care. Our research reviews actions that address the need of migrants in terms of health care in order to understand how, where, and who participates in this effort. Data were from desk or web research, declaration from organisations and their websites, information from WHO Country Offices. 154 NGOs were identified in the WHO European Region. 58% were direct health care providers while the remaining provided either mediation services or were part of a network organization. 173 national institutes (GOVs) were found; less than the 20% were directly or indirectly involved in health care, whereas the majority were involved in research, policy development, international relations and human rights. Some gaps, a certain fragmentation and lack of coordination were identified. WHO can play an overarching role in the exchange of expertise and harmonisation of the efforts in this field.

The human power amplifier technology at the University of California, Berkeley.

PubMed

Kazerooni, H

1996-01-01

A human's ability to perform physical tasks is limited by physical strength, not by intelligence. We define "extenders" as a class of robot manipulators worn by humans to augment human mechanical strength, while the wearer's intellect remains the central control system for manipulating the extender. Our research objective is to determine the ground rules for the design and control of robotic systems worn by humans through the design, construction, and control of several prototype experimental direct-drive/non-direct-drive multi-degree-of-freedom hydraulic/electric extenders. The design of extenders is different from the design of conventional robots because the extender interfaces with the human on a physical level. Two sets of force sensors measure the forces imposed on the extender by the human and by the environment (i.e., the load). The extender's compliances in response to such contact forces were designed by selecting appropriate force compensators. This paper gives a summary of some of the selected research efforts related to Extender Technology, carried out during 1980s. The references, at the end of this article, give detailed description of the research efforts.

The reductionist paradox: are the laws of chemistry and physics sufficient for the discovery of new drugs?

PubMed

Maggiora, Gerald M

2011-08-01

Reductionism is alive and well in drug-discovery research. In that tradition, we continually improve experimental and computational methods for studying smaller and smaller aspects of biological systems. Although significant improvements continue to be made, are our efforts too narrowly focused? Suppose all error could be removed from these methods, would we then understand biological systems sufficiently well to design effective drugs? Currently, almost all drug research focuses on single targets. Should the process be expanded to include multiple targets? Recent efforts in this direction have lead to the emerging field of polypharmacology. This appears to be a move in the right direction, but how much polypharmacology is enough? As the complexity of the processes underlying polypharmacology increase will we be able to understand them and their inter-relationships? Is "new" mathematics unfamiliar in much of physics and chemistry research needed to accomplish this task? A number of these questions will be addressed in this paper, which focuses on issues and questions not answers to the drug-discovery conundrum.

Robust Network Design - Connectivity and Beyond

DTIC Science & Technology

2015-01-15

utilize a heterogeneous set of physical links (RF, Optical/Laser and SATCOM), for interconnecting a set of terrestrial, space and highly mobile airborne...design of mobility patterns of airborne platforms to provide stable operating conditions,  the design of networks that enable graceful performance...research effort, Airborne Network research was primarily directed towards Mobile Ad-hoc Networks (MANET). From our experience in design and

Navy Budget (1992): Potential Reductions in Research, Development, Test, and Evaluation Programs

DTIC Science & Technology

1991-09-01

Army’s fiber optic guided missile employs a video camera and single spool fiber payout system to provide a contin- uous data link to a ground station for...January 1991 the Navy’s technical design agent for the MK-48 tor- pedo has been directing a major research and testing effort. The results of these

Next Steps in Attachment Theory.

PubMed

Bell, David C

2012-12-01

Thanks to the phenomenal success of attachment theory, great progress has been made in understanding child and adult relationships. The success of attachment theory opens the way to new research directions that can extend its successes even further. In particular, more work on the fundamental nature of attachment that respects recent biological research is important, as is concentrated effort on the related caregiving system.

Services and Resources to Engineers: A Case Study of Outreach and Marketing, Assessment, and Future Directions in a Research Library

ERIC Educational Resources Information Center

Torrence, Matt

2015-01-01

The literature, activities, and resource needs of engineering students and faculty provide insight into a demographic that is often among the early-adopters of new technologies, tools, and methods of sharing information. Despite the often non-bibliographic nature of their research efforts, there are numerous elements of the traditional service…

Next Steps in Attachment Theory

PubMed Central

Bell, David C.

2012-01-01

Thanks to the phenomenal success of attachment theory, great progress has been made in understanding child and adult relationships. The success of attachment theory opens the way to new research directions that can extend its successes even further. In particular, more work on the fundamental nature of attachment that respects recent biological research is important, as is concentrated effort on the related caregiving system. PMID:23504112

Neutron and Gamma Imaging for National Security Applications

NASA Astrophysics Data System (ADS)

Hornback, Donald

2017-09-01

The Department of Energy, National Nuclear Security Administration (NNSA), Office of Defense Nuclear Nonproliferation Research and Development (DNN R&D/NA-22) possesses, in part, the mission to develop technologies in support of nuclear security efforts in coordination with other U.S. government entities, such as the Department of Defense and the Department of Homeland Security. DNN R&D has long supported research in nuclear detection at national labs, universities, and through the small business innovation research (SBIR) program. Research topics supported include advanced detector materials and electronics, detection algorithm development, and advanced gamma/neutron detection systems. Neutron and gamma imaging, defined as the directional detection of radiation as opposed to radiography, provides advanced detection capabilities for the NNSA mission in areas of emergency response, international safeguards, and nuclear arms control treaty monitoring and verification. A technical and programmatic overview of efforts in this field of research will be summarized.

Large, horizontal-axis wind turbines

NASA Technical Reports Server (NTRS)

Linscott, B. S.; Perkins, P.; Dennett, J. T.

1984-01-01

Development of the technology for safe, reliable, environmentally acceptable large wind turbines that have the potential to generate a significant amount of electricity at costs competitive with conventional electric generating systems are presented. In addition, these large wind turbines must be fully compatible with electric utility operations and interface requirements. There are several ongoing large wind system development projects and applied research efforts directed toward meeting the technology requirements for utility applications. Detailed information on these projects is provided. The Mod-O research facility and current applied research effort in aerodynamics, structural dynamics and aeroelasticity, composite and hybrid composite materials, and multiple system interaction are described. A chronology of component research and technology development for large, horizontal axis wind turbines is presented. Wind characteristics, wind turbine economics, and the impact of wind turbines on the environment are reported. The need for continued wind turbine research and technology development is explored. Over 40 references are sited and a bibliography is included.

Direct Energy Conversion for Nuclear Propulsion at Low Specific Mass

NASA Technical Reports Server (NTRS)

Scott, John H.

2014-01-01

The project will continue the FY13 JSC IR&D (October-2012 to September-2013) effort in Travelling Wave Direct Energy Conversion (TWDEC) in order to demonstrate its potential as the core of a high potential, game-changing, in-space propulsion technology. The TWDEC concept converts particle beam energy into radio frequency (RF) alternating current electrical power, such as can be used to heat the propellant in a plasma thruster. In a more advanced concept (explored in the Phase 1 NIAC project), the TWDEC could also be utilized to condition the particle beam such that it may transfer directed kinetic energy to a target propellant plasma for the purpose of increasing thrust and optimizing the specific impulse. The overall scope of the FY13 first-year effort was to build on both the 2012 Phase 1 NIAC research and the analysis and test results produced by Japanese researchers over the past twenty years to assess the potential for spacecraft propulsion applications. The primary objective of the FY13 effort was to create particle-in-cell computer simulations of a TWDEC. Other objectives included construction of a breadboard TWDEC test article, preliminary test calibration of the simulations, and construction of first order power system models to feed into mission architecture analyses with COPERNICUS tools. Due to funding cuts resulting from the FY13 sequestration, only the computer simulations and assembly of the breadboard test article were completed. The simulations, however, are of unprecedented flexibility and precision and were presented at the 2013 AIAA Joint Propulsion Conference. Also, the assembled test article will provide an ion current density two orders of magnitude above that available in previous Japanese experiments, thus enabling the first direct measurements of power generation from a TWDEC for FY14. The proposed FY14 effort will use the test article for experimental validation of the computer simulations and thus complete to a greater fidelity the mission analysis products originally conceived for FY13.

Emerging inequality in effort: A longitudinal investigation of parental involvement and early elementary school-aged children's learning time in Japan.

PubMed

Matsuoka, Ryoji; Nakamuro, Makiko; Inui, Tomohiko

2015-11-01

While studies on effort (e.g., Carbonaro, 2005; Kariya, 2000, 2013) have revealed relationships among students' effort (e.g., self-reported learning time), socioeconomic status, and school-related factors (e.g., tracking) through secondary education data, whether and how the effort gap emerges and widens in the early years of compulsory education have not been researched. This study investigates the beginning of inequality in effort by using four waves (from first- to fourth-grade students) of the Longitudinal Survey of Babies in the 21st Century, collected in Japan. The results indicate that college-educated parents tend to employ parenting practices that directly and indirectly shape children's learning time; inequality in effort exists, and it becomes exacerbated partly because of parenting differences in a society with a relatively equal elementary education system. Copyright © 2015 Elsevier Inc. All rights reserved.

Evolution of Aerosol Research in India and the RAWEX–GVAX:An Overview

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krishna Moorthy, K.; Satheesh, S. K.; Kotamarthi, V. R.

Climate change has great significance in Asia in general, and India in particular; and atmospheric aerosols have a decisive role in this. The climate forcing potential of aerosols is closely linked to their optical, microphysical and chemical properties. Systematic efforts to characterize these properties over the Indian region started about 5 decades ago, and evolved over the years through concerted efforts in the form of long-term scientific programmes as well as concerted fields experiments. All these have resulted in this activity becoming one of the most vibrant fields of climate research in India and have brought several important issues inmore » the national and international foci. The field experiment, RAWEX-GVAX (Regional Aerosol Warming Experiment-Ganges Valley Aerosol Experiment), conducted during 2011-12 jointly by the US Department of Energy, Indian Space Research Organization and Department of Science and Technology, has emerged as a direct outcome of the above efforts. This overview provides a comprehensive account of the development of aerosol-climate research in India and south Asia, and the accomplishment and newer issues that warranted the above field campaign. Details of RAWEX-GVAX, the major outcomes and the subsequent and more recent efforts are presented, followed by the way forward in this field for the next several years to come.« less

Report to the congress on ocean pollution, monitoring and research October 1980 through September 1981

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1982-07-01

This report summarizes the results of FY 1981 National Oceanic and Atmospheric Administration (NOAA) monitoring and research efforts under Title II of the Marine Protection, Research, and Sanctuaries Act of 1972 (P.L. 92-532). Section 201 of Title II assigns responsibility to the Department of Commerce for a comprehensive and continuing program of monitoring and research regarding the effects of dumping material into ocean waters, coastal waters, and the Great Lakes. Section 202 of Title II directs the Secretary of Commerce, in consultation with other appropriate parts of the U.S. Government, to 'initiate a comprehensive and continuing program of research withmore » respect to the possible long-range effects of pollution, overfishing, and man-induced changes of ocean ecosystems.' The legislation also directs the Secretary of Commerce to report the findings from the monitoring and research programs to the Congress at least once a year. There are intrinsic difficulties, however, in distinguishing 'long-range' effects from the 'acute' effects of ocean dumping, or more generally of marine pollution. In response to these considerations and to the responsibilities assigned to NOAA under the National Ocean Pollution Planning Act (P.L. 95-273), NOAA has consolidated and coordinated its research efforts in these areas to make the overall program more cost-effective and productive.« less

Commentary: The Relative Research Unit: An Approach to Measuring and Encouraging Clinician Participation in Research Activities

PubMed Central

Embi, Peter J.; Tsevat, Joel

2013-01-01

Recent nationwide initiatives to accelerate clinical and translational research, including comparative effectiveness research, increasingly will require clinician participation in research-related activities at the point-of-care, activities such as participant recruitment for clinical research studies and systematic data collection. A key element to the success of such initiatives that has not yet been adequately addressed is how to provide incentives to clinicians for the time and effort that such participation will require. Models to calculate the value of clinical care services are commonly used to compensate clinicians, and similar models have been proposed to calculate and compensate researchers’ efforts. However, to the authors’ knowledge, no such model has been proposed for calculating the value of research-related activities performed by non-investigator clinicians, be they in academic or community settings. In this commentary, the authors propose a new model for doing just that. They describe how such a relative research unit model could be used to provide both direct and indirect incentives for clinician participation in research activities. Direct incentives could include financial compensation, while indirect incentives could include credit towards promotion and tenure and towards the maintenance of specialty board certification. The authors discuss the principles behind this relative research unit approach as well as ethical, funding, and other considerations to fully developing and deploying such a model, across academic environments first and then more broadly across the health care community. PMID:22201633

The Emergence of Postculturalism.

ERIC Educational Resources Information Center

Nucci, Larry; Neblo, Michael A.

1998-01-01

Argues that Baumrind's (1998) postculturalist stance reflects the direction of developmental psychology research, but her efforts to construct a complementary ethical theory fall short. Argues that her position suffers from internal contradictions and that her project can be salvaged by accommodation with elements of communicative discourse theory…

Evidence-based financial management.

PubMed

Finkler, Steven A; Henley, Richard J; Ward, David M

2003-10-01

Like the practice of evidence-based medicine, evidence-based financial management can be used by providers to improve results. The concept provides a framework that managers and researchers can use to help direct efforts in gathering and using evidence to support management decisions in health care.

75 FR 7448 - Species Recovery Grants to Tribes Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-19

... principal objective of the Program is to support recovery efforts that directly benefit threatened or... management, research, monitoring, and outreach activities or any combination thereof. For FY 2010, NOAA... (NMFS) jurisdiction depends in large part on working cooperatively with other management partners...

76 FR 70456 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-14

... in developing mechanisms for reviewing and disseminating Comparative Effectiveness Research (CER) and... through its Effective Healthcare Program (EHCP). CER directly compares the benefits, potential risks, and... augment AHRQ's existing CER dissemination efforts performed by the Eisenberg Center and other initiatives...

Biochemical Study of Mixed Culture Prototype in a Closed Ecological System

NASA Technical Reports Server (NTRS)

Tischer, R. G.

1960-01-01

Since June 1, 1960, the date of initiation of this research project, efforts have been directed toward studying cultural and fermentation patterns and the methodology of pure culture isolation of prototype microorganisms to be employed in closed ecological systems.

Nano-enabled drug delivery: a research profile.

PubMed

Zhou, Xiao; Porter, Alan L; Robinson, Douglas K R; Shim, Min Suk; Guo, Ying

2014-07-01

Nano-enabled drug delivery (NEDD) systems are rapidly emerging as a key area for nanotechnology application. Understanding the status and developmental prospects of this area around the world is important to determine research priorities, and to evaluate and direct progress. Global research publication and patent databases provide a reservoir of information that can be tapped to provide intelligence for such needs. Here, we present a process to allow for extraction of NEDD-related information from these databases by involving topical experts. This process incorporates in-depth analysis of NEDD literature review papers to identify key subsystems and major topics. We then use these to structure global analysis of NEDD research topical trends and collaborative patterns, inform future innovation directions. This paper describes the process of how to derive nano-enabled drug delivery-related information from global research and patent databases in an effort to perform comprehensive global analysis of research trends and directions, along with collaborative patterns. Copyright © 2014 Elsevier Inc. All rights reserved.

Legislation may support STaRS

NASA Astrophysics Data System (ADS)

Congressman Vernon Ehlers (R, MI) has offered three bills in the House of Representatives that support K-12 science, math, engineering, and technology (SMET) education (Eos, April 18, 2000). Although no dollar amounts are mentioned, the three bills contain numerous provisions for improving and expanding SMET education activities at the Department of Education and the National Science Foundation, and for tax incentives for pre-service teacher education and in-service professional development. Of particular interest is Section 15 of H.R. 4271, the National Science Education Act, which directs the NSF to provide scholarships for K-12 teachers to participate in research programs in government agencies, colleges and universities, or private research establishments. Such scholarships could support AGU's Science Teacher and Research Scientist (STaRS) effort, which is intended to provide opportunities for teachers to participate in research under the direction of AGU scientists, and for those same scientists to participate in science teaching under the teachers' direction.

Co-Operative Advances in Behavioral Health and Performance Research and Operations

NASA Technical Reports Server (NTRS)

VanderArk, Stephen T.; Leveton, Lauren B.

2011-01-01

In organizations that engage in both operations and applied research, with operational needs guiding research questions and research informing improved operations, the ideal goal is a synergy of ideas and information. In reality, this ideal synergy is often lacking. Real-time operational needs driving day-to-day decisions, lack of communication, lag time in getting research advances plugged into operations can cause both areas to suffer from this gap between operations and research. At Johnson Space Center, the Behavior Health and Performance group (BHP) strives to bridge this gap by following a Human Research Program framework: Expectations of future operational needs identify the knowledge gaps; the gaps in turn guide research leading to a product that is transitioned into operations. Thus, the direction those of us in research take is in direct response to current and future needs of operations. Likewise, those of us in operations actively seek knowledge that is supported by evidence-based research. We make an ongoing effort to communicate across the research and operations gap by working closely with each other and making a conscious effort to keep each other informed. The objective of the proposed panel discussion is to demonstrate through the following presentations the results of a successful collaboration between research and operations and to provide ASMA members with more practical knowledge and strategies for building these bridges to serve our field of practice well. The panel will consist of six presenters from BHP operations, internal BHP research, and external research instigated by BHP who together represent the entire BHP Research Transition to Operations Framework

Integration of Civilian and Army Research and Development

DTIC Science & Technology

1949-05-24

top level impairs the et.:reati veness of the over-all program. for national security. b. Proposals to establish a National Science Foundation directly...deVJelopments in their respective branches. 5. CONOLUSIONS.--a. That a National Science Foundation designed to provide policy direction and control...development. 6. ACTION REOOMMENDED.-a. That the Armed Forces renew their efforts to secure the establishment of a National Science Foundation . b. That

1983 AFOSR/AFRPL Chemical Rocket Research Meeting, Abstracts and Agenda. Includes: Abstracts on Advanced Diagnostics of Reacting Flow, 28 February - 3 March 1983, Lancaster, California.

DTIC Science & Technology

1983-02-01

blow-off stability and fractional conversion was evaluated for design of an experimental study of these phenomena. The apparatus designed will be...the development of an array of experimental methods and test strategies designed to unravel a complex process that is very difficult to observe directly...this effort of lead field theoretic analysis as a design basis has made that possible. The experimental phase of the effort has three major

An Investigation of the Flow Physics of Acoustic Liners by Direct Numerical Simulation

NASA Technical Reports Server (NTRS)

Watson, Willie R. (Technical Monitor); Tam, Christopher

2004-01-01

This report concentrates on reporting the effort and status of work done on three dimensional (3-D) simulation of a multi-hole resonator in an impedance tube. This work is coordinated with a parallel experimental effort to be carried out at the NASA Langley Research Center. The outline of this report is as follows : 1. Preliminary consideration. 2. Computation model. 3. Mesh design and parallel computing. 4. Visualization. 5. Status of computer code development. 1. Preliminary Consideration.

The Department of Defense Congressionally Directed Medical Research Program: innovations in the federal funding of biomedical research.

PubMed

Young-McCaughan, Stacey; Rich, Irene M; Lindsay, Gaylord C; Bertram, Kenneth A

2002-04-01

In response to the lobbying efforts of the women's advocacy movement, in 1993 Congress authorized funds for a substantial increase in support of new and promising research aimed at the eradication of breast cancer. This appropriation resulted in a major expansion of the United States Army Medical Research and Materiel Command, Department of Defense Breast Cancer Research Program. The Office of Congressionally Directed Medical Research Programs was established within the United States Army Medical Research and Materiel Command to facilitate the management of the expanded extramural research program. Since that time, the programs have grown to include not just breast cancer but also prostate cancer, ovarian cancer, and neurofibromatosis. The unique appropriations to the Office of Congressionally Directed Medical Research Programs has resulted in a number of programmatic innovations. These include development of unique mechanisms of grant support, inclusion of consumer advocates on peer and programmatic review panels, and the introduction of criteria-based evaluation and scoring in peer review. This article describes these novel scientific management strategies and outlines their success in meeting program visions and goals.

The complexity of organizational change: describing communication during organizational turbulence.

PubMed

Salem, Philip

2013-01-01

Organizational researchers and practitioners have been interested in organizational change for some time. Historically, they have directed most of their efforts at improving the efficiency of planned top-down change. These efforts were strategic attempts at altering parameters leading to transformational change. Most efforts failed to meet their intended purposes. Transformational organizational change has not been likely. The legitimate systems have been robust. There has been little systematic investigation of the communication occurring during these efforts. The purpose of this essay is to describe results of a mixed methods research project answering two research questions. (a) How do organizational members communicate during a time of turbulence? (b) What features of this communication suggest the potential for or resistance to transformative change? Comparing the results at the beginning of the period to other periods, gives insight into how social actors communicate and enact the organization during a threshold period where transformational change was possible. Results reveal identifiable patterns of communication as communication strategies, parameters, or basins of attraction. The overall pattern explains how micro communication patterns intersect and how the accumulation of these patterns may resist or accomplish change at a macro level.

Historical Review of Uncommanded Lateral-Directional Motions at Transonic Conditions

NASA Technical Reports Server (NTRS)

Chambers, Joseph R.; Hall, Robert M.

2003-01-01

This paper presents the results of a survey of past experiences with uncommanded lateral-directional motions at transonic speeds during specific military aircraft programs. The effort was undertaken to provide qualitative and quantitative information on past airplane programs that might be of use to the participants in the joint NASA/Navy/Air Force Abrupt Wing Stall (AWS) Program. The AWS Program was initiated because of the experiences of the F/A-l8E/F development program, during which unexpected, severe wing-drop motions were encountered by preproduction aircraft at transonic conditions. These motions were judged to be significantly degrading to the primary mission requirements of the aircraft. Although the problem was subsequently solved for the production version of the F/A-l8E/F, a high-level review panel emphasized the poor understanding of such phenomena and issued a strong recommendation to: "Initiate a national research effort to thoroughly and systematically study the wing drop phenomena." A comprehensive, cooperative NASA/Navy/Air Force AWS Program was designed to respond to provide the required technology requirements. As part of the AWS Program, a work element was directed at a historical review of wing-drop experiences in past aircraft development programs at high subsonic and transonic speeds. In particular, information was requested regarding: specific aircraft configurations that exhibited uncommanded motions and the nature of the motions; geometric characteristics of the air- planes; flight conditions involved in occurrences; relevant data, including wind-tunnel, computational, and flight sources; figures of merit used for analyses; and approaches used to alleviate the problem. An attempt was also made to summarize some of the more important lessons learned from past experiences, and to recommend specific research efforts. In addition to providing technical information to assist the AWS research objectives, the study produced fundamental information regarding the historical challenge of uncommanded lateral-directional motions at transonic conditions and the associated aerodynamic phenomena.

Historical Review of Uncommanded Lateral-Directional Motions At Transonic Conditions (Invited)

NASA Technical Reports Server (NTRS)

Chambers, Joseph R.; Hall, Robert M.

2003-01-01

This paper presents the results of a survey of past experiences with uncommanded lateral-directional motions at transonic speeds during specific military aircraft programs. The effort was undertaken to provide qualitative and quantitative information on past airplane programs that might be of use to the participants in the joint NASA/Navy/Air Force Abrupt Wing Stall (AWS) Program. The AWS Program was initiated because of the experiences of the F/A-18E/F development program, during which unexpected, severe wing-drop motions were encountered by preproduction aircraft at transonic conditions. These motions were judged to be significantly degrading to the primary mission requirements of the aircraft. Although the problem was subsequently solved for the production version of the F/A-l8E/F, a high-level review panel emphasized the poor understanding of such phenomena and issued a strong recommendation to: Initiate a national research effort to thoroughly and systematically study the wing drop phenomena. A comprehensive, cooperative NASA/Navy/Air Force AWS Program was designed to respond to provide the required technology requirements. As part of the AWS Program, a work element was directed at a historical review of wing-drop experiences in past aircraft development programs at high subsonic and transonic speeds. In particular, information was requested regarding: specific aircraft configurations that exhibited uncommanded motions and the nature of the motions; geometric characteristics of the air- planes; flight conditions involved in occurrences; relevant data, including wind-tunnel, computational, and flight sources; figures of merit used for analyses; and approaches used to alleviate the problem. An attempt was also made to summarize some of the more important lessons learned from past experiences, and to recommend specific research efforts. In addition to providing technical information to assist the AWS research objectives, the study produced fundamental information regarding the historical challenge of uncommanded lateral-directional motions at transonic conditions and the associated aerodynamic phenomena.

The Streetlight Effect in Type 1 Diabetes

PubMed Central

Battaglia, Manuela

2015-01-01

In the nearly 100 years since the discovery of therapeutic insulin, significant research efforts have been directed at finding the underlying cause of type 1 diabetes (T1D) and developing a “cure” for the disease. While progress has clearly been made toward each of these goals, neither vision has been fulfilled. With increasing pressure from both public and private funders of diabetes research, growing impatience of those with T1D at the lack of practical discoveries, increased competition for research funds, uncertainties on the reproducibility of published scientific data, and questions regarding the value of animal models, the current research environment has become extraordinarily difficult to traverse from the perspective of investigators. As a result, there is an increasing pressure toward performance of what might be considered “safe” research, where the aim is to affirm existing dogmas rather than to pioneer efforts involving unconventional thought. Psychologists refer to this practice as “observational bias” while cartoonists label the process the “streetlight effect.” In this Perspective, we consider notions in T1D research that should be subject to bold question and provide additional concepts, many somewhat orphan to research efforts, whose investigation could lead to a means for truly identifying the cause of and a cure for T1D. PMID:25805758

KSC-02pd0617

NASA Image and Video Library

2002-04-29

KENNEDY SPACE CENTER, FLA. -- Florida Representative Bob Allen speaks to attendees at the opening ceremony kicking off a new program known as SABRE, Space Agricultural Biotechnology Research and Education. The program is a combined effort of the University of Florida and NASA. SABRE will focus on the discovery, development and application of the biological aspects of advanced life support strategies. The program will include faculty from UF's Institute of Food and Agricultural Sciences, who will be located at both KSC - in the state-owned Space Experiment Research and Processing Laboratory (SERPL) being built there - and UF in Gainesville. SABRE will be directed by Robert Ferl, professor in the horticultural sciences department and assistant director of UF's Biotechnology Program. He will be responsible for coordinating the research and education efforts of UF and NASA

Lactate biosensors: current status and outlook.

PubMed

Rassaei, Liza; Olthuis, Wouter; Tsujimura, Seiya; Sudhölter, Ernst J R; van den Berg, Albert

2014-01-01

Many research efforts over the last few decades have been devoted to sensing lactate as an important analytical target in clinical care, sport medicine, and food processing. Therefore, research in designing lactate sensors is no longer in its infancy and now is more directed toward viable sensors for direct applications. In this review, we provide an overview of the most immediate and relevant developments toward this end, and we discuss and assess common transduction approaches. Further, we critically describe the pros and cons of current commercial lactate sensors and envision how future sensing design may benefit from emerging new technologies.

OAST space power technology program

NASA Technical Reports Server (NTRS)

Mullin, J. P.

1978-01-01

The current research and technology (R and T) base program is first described, then special attention is directed toward outlining a new system technology specifically oriented toward providing the utility power plant technology base for semi-permanent earth orbital facilities expected to be needed in the middle to late 1980's. The R and T program involves five areas of research: (1) photovoltaic energy conversion; (2) chemical energy conversion and storage; (3) thermal-to-electric conversion; (4) environment interactions; and (5) power systems management and distribution. The general objectives and planned direction of efforts in each of these areas is summarized.

The future of dentistry: new challenges, new directions.

PubMed Central

Sinkford, J. C.

1990-01-01

The challenge to our profession today is to improve the quality of oral health while overcoming both extrinsic and intrinsic factors which may adversely affect our progress toward this goal. The combined efforts of dental education, dental research, and dental practice will be needed to enable us to maintain the quality of our present system and to meet the myriad changes that will chart our new directions in the future. Our unified efforts can make a difference and, thereby, ensure a meaningful and productive future for dentistry in our country and throughout the world. Let us show the world that the future of dentistry matters to us and that we look to the future with great anticipation and optimism. PMID:2352286

The paradox of scientific excellence and the search for productivity in pharmaceutical research and development.

PubMed

Grasela, T H; Slusser, R

2014-05-01

Scientific advances in specialty areas are proceeding at a rapid rate, but the research and development enterprise seems unable to take full advantage. Harnessing the steady stream of knowledge and inventions from different disciplines is the critical management issue of our time. This article suggests a framework for a management-directed effort to improve productivity by enhancing interdisciplinary collaboration.

An Examination of Teachers' Perceptions of Principal Support for Change and Teachers' Collaboration and Communication around Literacy Instruction in Reading First Schools

ERIC Educational Resources Information Center

Berebitsky, Dan; Goddard, Roger D.; Carlisle, Joanne F.

2014-01-01

Background/Context: Little research has directly examined whether principal leadership can increase the degree to which teachers work together regularly in focused ways around content. Prior research has shown that reform efforts seeking to alter the process of teaching can be successful if teachers collaborate to build capacity and improve…

Off-road axle detection sensor (ORADS) : occlusion feasibility study, final technical report, 27 August, 1997.

DOT National Transportation Integrated Search

1997-08-27

The work accomplished under this initiative is in direct relation to the development effort proposed by Spectra : Research, Inc. (S*R) for an "Off-Road Axle Detection Sensor (ORADS)". The feasibility study was performed to : investigate potential occ...

A Framework for Comparing Groups of Documents

DTIC Science & Technology

2015-09-21

Science Foundation (NSF), the National Institutes of Health (NIH), and the Department of Defense (DoD), are of- ten in the position of reviewing...documents. Here, we provide two motivating examples. 1. Program Reviews. To better direct research efforts, funding organizations such as the National

The Politics of Extension Water Programming: Determining if Affiliation Impacts Participation

ERIC Educational Resources Information Center

Owens, Courtney T.; Lamm, Alexa J.

2017-01-01

Research has found levels of engagement in environmental behaviors and participation in Extension programming around environmental issues are directly associated with political affiliation. Democrat and Independent parties encourage members to vote for stricter environmental regulations, such as water conservation efforts, while Republicans…

Increased Rail Transit Vehicle Crashworthiness in Head-On Collisions. Volume III. Guidelines for Evaluation and Development of New Railcar Designs.

DOT National Transportation Integrated Search

1980-06-01

As systems manager for the Urban Mass Transportation Administration (UMTA) Rail System Supporting Technology Program, the Transportation Systems Center (TSC) is conducting research and development efforts directed toward the introduction of improved ...

Off-road axle detection sensor (ORADS) : occlusion feasibility study, executive summary, 27 August, 1997.

DOT National Transportation Integrated Search

1997-08-27

The work accomplished under this initiative is in direct relation to the development effort proposed by Spectra Research, Inc. (S*R) for an "Off-Road Axle Detection Sensor (ORADS)". The feasibility study was performed to investigate potential occlusi...

Sediment characteristics and microbial communities associated with methane production in a eutrophic reservoir

EPA Science Inventory

Methane (CH4), a potent greenhouse gas, is known to be produced and emitted from freshwater systems. Recently, extensive efforts have been directed toward quantifyingmethane emissions fromthese ecosystems, while additional research has focused on factors that may influence emissi...

Monitoring Design for Source Identification in Water Distribution Systems

EPA Science Inventory

The design of sensor networks for the purpose of monitoring for contaminants in water distribution systems is currently an active area of research. Much of the effort has been directed at the contamination detection problem and the expression of public health protection objective...

Large eddy simulations and direct numerical simulations of high speed turbulent reacting flows

NASA Technical Reports Server (NTRS)

Givi, P.; Madnia, C. K.; Steinberger, C. J.; Frankel, S. H.

1992-01-01

The basic objective of this research is to extend the capabilities of Large Eddy Simulations (LES) and Direct Numerical Simulations (DNS) for the computational analyses of high speed reacting flows. In the efforts related to LES, we were primarily involved with assessing the performance of the various modern methods based on the Probability Density Function (PDF) methods for providing closures for treating the subgrid fluctuation correlations of scalar quantities in reacting turbulent flows. In the work on DNS, we concentrated on understanding some of the relevant physics of compressible reacting flows by means of statistical analysis of the data generated by DNS of such flows. In the research conducted in the second year of this program, our efforts focused on the modeling of homogeneous compressible turbulent flows by PDF methods, and on DNS of non-equilibrium reacting high speed mixing layers. Some preliminary work is also in progress on PDF modeling of shear flows, and also on LES of such flows.

Investigating Student Communities with Network Analysis of Interactions in a Physics Learning Center

NASA Astrophysics Data System (ADS)

Brewe, Eric; Kramer, Laird; O'Brien, George

2009-11-01

We describe our initial efforts at implementing social network analysis to visualize and quantify student interactions in Florida International University's Physics Learning Center. Developing a sense of community among students is one of the three pillars of an overall reform effort to increase participation in physics, and the sciences more broadly, at FIU. Our implementation of a research and learning community, embedded within a course reform effort, has led to increased recruitment and retention of physics majors. Finn and Rock [1997] link the academic and social integration of students to increased rates of retention. To identify these interactions, we have initiated an investigation that utilizes social network analysis to identify primary community participants. Community interactions are then characterized through the network's density and connectivity, shedding light on learning communities and participation. Preliminary results, further research questions, and future directions utilizing social network analysis are presented.

The role of the Department of Defense in PACS and telemedicine research and development.

PubMed

Mogel, Greg T

2003-01-01

The United States Department of Defense (DOD) has played a leading role in the movement of digital imaging, picture archiving and communications systems, and more recently telemedicine with its associated technologies into the mainstream of healthcare. Beginning in the 1980s with domestic implementations, and followed in the 1990s by both small and large-scale military deployments, these technologies have been put into action with varying degrees of success. These efforts however, have always served as a guidepost for similar civilian efforts and the establishment of a marketplace for the technologies. This paper examines the history of the DOD's role in these areas, the projects and programs established, assessing their current state of development and identifying the future direction of the DOD's research and implementation efforts in telemedicine and advanced medical technologies. Copyright 2002 Published by Elsevier Science Ltd.

Identifying alternate pathways for climate change to impact inland recreational fishers

USGS Publications Warehouse

Hunt, Len M.; Fenichel, Eli P.; Fulton, David C.; Mendelsohn, Robert; Smith, Jordan W.; Tunney, Tyler D.; Lynch, Abigail J.; Paukert, Craig P.; Whitney, James E.

2016-01-01

Fisheries and human dimensions literature suggests that climate change influences inland recreational fishers in North America through three major pathways. The most widely recognized pathway suggests that climate change impacts habitat and fish populations (e.g., water temperature impacting fish survival) and cascades to impact fishers. Climate change also impacts recreational fishers by influencing environmental conditions that directly affect fishers (e.g., increased temperatures in northern climates resulting in extended open water fishing seasons and increased fishing effort). The final pathway occurs from climate change mitigation and adaptation efforts (e.g., refined energy policies result in higher fuel costs, making distant trips more expensive). To address limitations of past research (e.g., assessing climate change impacts for only one pathway at a time and not accounting for climate variability, extreme weather events, or heterogeneity among fishers), we encourage researchers to refocus their efforts to understand and document climate change impacts to inland fishers.

Effortful versus automatic emotional processing in schizophrenia: Insights from a face-vignette task.

PubMed

Patrick, Regan E; Rastogi, Anuj; Christensen, Bruce K

2015-01-01

Adaptive emotional responding relies on dual automatic and effortful processing streams. Dual-stream models of schizophrenia (SCZ) posit a selective deficit in neural circuits that govern goal-directed, effortful processes versus reactive, automatic processes. This imbalance suggests that when patients are confronted with competing automatic and effortful emotional response cues, they will exhibit diminished effortful responding and intact, possibly elevated, automatic responding compared to controls. This prediction was evaluated using a modified version of the face-vignette task (FVT). Participants viewed emotional faces (automatic response cue) paired with vignettes (effortful response cue) that signalled a different emotion category and were instructed to discriminate the manifest emotion. Patients made less vignette and more face responses than controls. However, the relationship between group and FVT responding was moderated by IQ and reading comprehension ability. These results replicate and extend previous research and provide tentative support for abnormal conflict resolution between automatic and effortful emotional processing predicted by dual-stream models of SCZ.

The History, Status, Gaps, and Future Directions of Neurotoxicology in China.

PubMed

Cai, Tongjian; Luo, Wenjing; Ruan, Diyun; Wu, Yi-Jun; Fox, Donald A; Chen, Jingyuan

2016-06-01

Rapid economic development in China has produced serious ecological, environmental, and health problems. Neurotoxicity has been recognized as a major public health problem. The Chinese government, research institutes, and scientists conducted extensive studies concerning the source, characteristics, and mechanisms of neurotoxicants. This paper presents, for the first time, a comprehensive history and review of major sources of neurotoxicants, national bodies/legislation engaged, and major neurotoxicology research in China. Peer-reviewed research and pollution studies by Chinese scientists from 1991 to 2015 were examined. PubMed, Web of Science and Chinese National Knowledge Infrastructure (CNKI) were the major search tools. The central problem is an increased exposure to neurotoxicants from air and water, food contamination, e-waste recycling, and manufacturing of household products. China formulated an institutional framework and standards system for management of major neurotoxicants. Basic and applied research was initiated, and international cooperation was achieved. The annual number of peer-reviewed neurotoxicology papers from Chinese authors increased almost 30-fold since 2001. Despite extensive efforts, neurotoxicity remains a significant public health problem. This provides great challenges and opportunities. We identified 10 significant areas that require major educational, environmental, governmental, and research efforts, as well as attention to public awareness. For example, there is a need to increase efforts to utilize new in vivo and in vitro models, determine the potential neurotoxicity and mechanisms involved in newly emerging pollutants, and examine the effects and mechanisms of mixtures. In the future, we anticipate working with scientists worldwide to accomplish these goals and eliminate, prevent and treat neurotoxicity. Cai T, Luo W, Ruan D, Wu YJ, Fox DA, Chen J. 2016. The history, status, gaps, and future directions of neurotoxicology in China. Environ Health Perspect 124:722-732; http://dx.doi.org/10.1289/ehp.1409566.

Building interdisciplinary research models: a didactic course to prepare interdisciplinary scholars and faculty.

PubMed

Larson, Elaine L; Landers, Timothy F; Begg, Melissa D

2011-02-01

Many academicians assume that anyone can engage in interdisciplinary research, but it is clear that successful interdisciplinary efforts require mastery of specific competencies that can be learned and improved. This paper describes the development and implementation of a course designed for Master's, pre- and postdoctoral students and research faculty on models of interdisciplinary research skills, based on a set of core competencies. Major challenges included working through institutional structures that made it difficult to offer cross-school courses, and interpersonal challenges among a diverse group of students from a number of disciplines. Although universities may be poised for interdisciplinary research, strategies for faculty preparation and support are lacking. Institutions embracing the concept of team and interdisciplinary science must focus not only on the structural barriers and facilitators, but also on direct support to faculty. The didactic course described in this paper is one approach to enhance interdisciplinary research skills of scholars-in-training and faculty, and we recommend that similar efforts be widely implemented. © 2011 Wiley Periodicals, Inc.

Top 40 priorities for science to inform conservation and management policy in the United States

USGS Publications Warehouse

Fleishman, Erica; Blockstein, David E.; Hall, John A.; Mascia, Michael B.; Rudd, Murray A.; Scott, J. Michael; Sutherland, William J.; Bartuska, Ann M.; Brown, A. Gordon; Christen, Catherine A.; Clement, Joel P.; DellaSala, Dominick; Duke, Clifford D.; Fiske, Shirley J.; Gosnell, Hannah; Haney, J. Christopher; Hutchins, Michael; Klein, Mary L.; Marqusee, Jeffrey; Noon, Barry R.; Nordgren, John R.; Orbuch, Paul M.; Powell, Jimmie; Quarles, Steven P.; Saterson, Kathryn A.; Stein, Bruce A.; Webster, Michael S.; Vedder, Amy

2011-01-01

To maximize the utility of research to decisionmaking, especially given limited financial resources, scientists must set priorities for their efforts. We present a list of the top 40 high-priority, multidisciplinary research questions directed toward informing some of the most important current and future decisions about management of species, communities, and ecological processes in the United States. The questions were generated by an open, inclusive process that included personal interviews with decisionmakers, broad solicitation of research needs from scientists and policymakers, and an intensive workshop that included scientifically oriented individuals responsible for managing and developing policy related to natural resources. The process differed from previous efforts to set priorities for conservation research in its focus on the engagement of decisionmakers in addition to researchers. The research priorities emphasized the importance of addressing societal context and exploration of trade-offs among alternative policies and actions, as well as more traditional questions related to ecological processes and functions.

Proceedings of the Eleventh Annual Precise Time and Time Interval (PTTI) Application and Planning Meeting. [conference

NASA Technical Reports Server (NTRS)

Wardrip, S. C. (Editor)

1979-01-01

Thirty eight papers are presented addressing various aspects of precise time and time interval applications. Areas discussed include: past accomplishments; state of the art systems; new and useful applications, procedures, and techniques; and fruitful directions for research efforts.

7 CFR 3406.26 - Monitoring progress of funded projects.

Code of Federal Regulations, 2010 CFR

2010-01-01

... efforts, future directions for education reform, research project management, advancing a field of science... the first year of the project and annually thereafter during the life of the grant. Generally, the... the food and agricultural sciences higher education system; and data on project personnel and...

An Overview of Science Education in the Caribbean: Research, Policy and Practice.

ERIC Educational Resources Information Center

Sweeney, Aldrin E.

2003-01-01

Analyzes science education in the Caribbean and provides examples of science education policy and practice. Emphasizes large-scale national efforts in Barbados, Bermuda, and Jamaica. Discusses and provides recommendations for future directions in science education in these countries. (Contains 88 references.) (Author/NB)

Health cyberinfrastructure for collaborative use-inspired research and practice.

PubMed

Chismar, William; Horan, Thomas A; Hesse, Bradford W; Feldman, Sue S; Shaikh, Abdul R

2011-05-01

Rapid advances in information and networking technologies have greatly expanded the modes for conducting business and science. For the past two decades, the National Science Foundation (NSF) has been supporting efforts to develop a comprehensive cyberinfrastructure with the goal of transforming the nature of scientific investigations. More recently, the NIH began supporting efforts to develop a cyberinfrastructure of healthcare research and practice. However, the best structure and applications of cyberinfrastructure in health care have yet to be defined. To address these issues, the NIH and the Kay Center for E-Health Research at Claremont Graduate University sponsored a symposium on "Cyberinfrastructure for Public Health and Health Services: Research and Funding Directions." The symposium convened researchers, practitioners, and federal funders to discuss how to further cyberinfrastructure systems and research in the public health and health services sectors. This paper synthesizes findings of the symposium, the goals of which were to determine the dynamics necessary for executing and utilizing cyberinfrastructure in public health and health services; examine the requirements of transdisciplinary collaboration; and identify future research directions. A multi-faceted conception of use-inspired research for cyberinfrastructure is developed. Use-inspired research aims to further basic theory but is grounded, inspired, and informed by practical problems. A cyberinfrastructure framework is presented that incorporates three intersecting dimensions: research-practice, health services-public health, and social-technical dimensions. Within this framework, this paper discusses the ways in which cyberinfrastructure provides opportunities to integrate across these dimensions to develop research and actions that can improve both clinical outcomes and public health. Copyright © 2011 American Journal of Preventive Medicine. All rights reserved.

A system for the real time, direct measurement of natural gas flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sowell, T.

1995-12-31

PMI/Badger Meter, Inc. with partial sponsorship from the Gas Research Institute, has designed and developed direct measurement total energy flow metering instrumentation. As industry demands for improved accuracy and speed of measurement have increased so has the complexity of the overall hardware and software systems. Considering traditional system approaches, few companies have the in house capability of maintaining a complete system. This paper addresses efforts to implement a direct, total gas energy flow metering system which is simple to use and cost effective.

Behavioral Self-Regulation and Weight-Related Behaviors in Inner-City Adolescents: A Model of Direct and Indirect Effects

PubMed Central

Isasi, Carmen R.; Wills, Thomas A.

2012-01-01

Background This study examined the association of two distinct self-regulation constructs, effortful control and dysregulation, with weight-related behaviors in adolescents and tested whether these effects were mediated by self-efficacy variables. Methods A school-based survey was conducted with 1771 adolescents from 11 public schools in the Bronx, New York. Self-regulation was assessed by multiple indicators and defined as two latent constructs. Dependent variables included fruit/vegetable intake, intake of snack/junk food, frequency of physical activity, and time spent in sedentary behaviors. Structural equation modeling examined the relation of effortful control and dysregulation to lifestyle behaviors, with self-efficacy variables as possible mediators. Results Study results showed that effortful control had a positive indirect effect on fruit and vegetable intake, mediated by self-efficacy, as well as a direct effect. Effortful control also had a positive indirect effect on physical activity, mediated by self-efficacy. Dysregulation had direct effects on intake of junk food/snacks and time spent in sedentary behaviors. Conclusions These findings indicate that self-regulation characteristics are related to diet and physical activity and that some of these effects are mediated by self-efficacy. Different effects were noted for the two domains of self-regulation. Prevention researchers should consider including self-regulation processes in programs to improve health behaviors in adolescents. PMID:23243551

Cognitive dissonance in children: justification of effort or contrast?

PubMed

Alessandri, Jérôme; Darcheville, Jean-Claude; Zentall, Thomas R

2008-06-01

Justification of effort is a form of cognitive dissonance in which the subjective value of an outcome is directly related to the effort that went into obtaining it. However, it is likely that in social contexts (such as the requirements for joining a group) an inference can be made (perhaps incorrectly) that an outcome that requires greater effort to obtain in fact has greater value. Here we present evidence that a cognitive dissonance effect can be found in children under conditions that offer better control for the social value of the outcome. This effect is quite similar to contrast effects that recently have been studied in animals. We suggest that contrast between the effort required to obtain the outcome and the outcome itself provides a more parsimonious account of this phenomenon and perhaps other related cognitive dissonance phenomena as well. Research will be needed to identify cognitive dissonance processes that are different from contrast effects of this kind.

Directions for the International Society for Research on Internet Interventions (ISRII).

PubMed

Ritterband, Lee M; Andersson, Gerhard; Christensen, Helen M; Carlbring, Per; Cuijpers, Pim

2006-09-29

In 2004, the International Society for Research on Internet Interventions (ISRII) was formed to encourage eHealth researchers to collaborate in their efforts to further the science behind developing, testing, and disseminating Web-based treatment programs. The group held its second meeting (April 2006) to clarify the Society's direction and identify key issues that need addressing in the field. These issues are identified and examined in the current paper. Given the success of using the Internet to treat a range of medical and mental health problems, and the growing need for better dissemination of health care, Internet interventions will almost certainly play a prominent role in global health. ISRII plans to provide the necessary venue to ensure the science driving this field is strong, enabling researchers to conduct the highest quality research and permitting meaningful conclusions from completed studies.

Transmission, Control and Treatment of Infectious Diseases of Military Importance in Equatorial Asia

DTIC Science & Technology

1989-06-22

IMN), which is commonly reported in Malaysia, is believed to be caused by the Epstein - Barr virus and is characterized by fever, lymphadenopathy...the development of an inexpensive and efficacious vaccine against the malaria parasites Plasmodium falciparum and P. vivax. This change in research... vaccine efforts are directed toward developing a vaccine against P. falciparum and P. vivax sporozoites. Accordingly, several WRAIR overseas research

Gay-Straight Alliances as Settings for Youth Inclusion and Development: Future Conceptual and Methodological Directions for Research on These and Other Student Groups in Schools

ERIC Educational Resources Information Center

Poteat, V. Paul; Yoshikawa, Hirokazu; Calzo, Jerel P.; Russell, Stephen T.; Horn, Stacey

2017-01-01

Outside the immediate classroom setting, efforts within other school spaces also can shape school climate, address inequality, and affect student performance. Nevertheless, in this respect there has been little research on school-based extracurricular groups focused on issues of social inclusion and justice. An exception to this lack of focus has…

Study of the application of advanced technologies to long-range transport aircraft. Volume 2: Research and development requirements

NASA Technical Reports Server (NTRS)

Lange, R. H.; Sturgeon, R. F.; Adams, W. E.; Bradley, E. S.; Cahill, J. F.; Eudaily, R. R.; Hancock, J. P.; Moore, J. W.

1972-01-01

Investigations were conducted to evaluate the relative benefits attainable through the exploitation of advanced technologies and to identify future research and development efforts required to permit the application of selected technologies to transport aircraft entering commercial operation in 1985. Results show that technology advances, particularly in the areas of composite materials, supercritical aerodynamics, and active control systems, will permit the development of long-range, high-payload commercial transports operating at high-subsonic speeds with direct operating costs lower than those of current aircraft. These advanced transports also achieve lower noise levels and lower engine pollutant emissions than current transports. Research and development efforts, including analytical investigations, laboratory test programs, and flight test programs, are required in essentially all technology areas to achieve the potential technology benefits.

An overview of NASA research on positive displacement general-aviation engines

NASA Technical Reports Server (NTRS)

Kempke, E. E., Jr.

1980-01-01

The research and technology program related to improved and advanced general aviation engines is described. Current research is directed at the near-term improvement of conventional air-cooled spark-ignition piston engines and at future alternative engine systems based on all-new spark-ignition piston engines, lightweight diesels, and rotary combustion engines that show potential for meeting program goals in the midterm and long-term future. The conventional piston engine activities involve efforts on applying existing technology to improve fuel economy, investigation of key processes to permit leaner operation and reduce drag, and the development of cost effective technology to permit flight at high-altitudes where fuel economy and safety are improved. The advanced engine concepts activities include engine conceptual design studies and enabling technology efforts on the critical or key technology items.

Research colloquium on occupational respiratory diseases: a conference in Cuba (1984)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenstock, L.; Orris, P.

At an international conference in Havana, Cuba, March 19-21, 1984, health professional from the US, Canada, and Cuba participated in a research colloquium on occupational lung diseases. Participants and speakers discussed the state of the art of knowledge, research, and management of key occupational lung diseases, and suggested directions for future efforts. Differences among the three countries in terms of the medical, economic, and social aspects of defining, treating, and compensating occupational diseases were also considered.

Climate Change Effects on Respiratory Health: Implications for Nursing.

PubMed

George, Maureen; Bruzzese, Jean-Marie; Matura, Lea Ann

2017-11-01

Greenhouse gases are driving climate change. This article explores the adverse health effects of climate change on a particularly vulnerable population: children and adults with respiratory conditions. This review provides a general overview of the effects of increasing temperatures, extreme weather, desertification, and flooding on asthma, chronic obstructive lung disease, and respiratory infections. We offer suggestions for future research to better understand climate change hazards, policies to support prevention and mitigation efforts targeting climate change, and clinical actions to reduce individual risk. Climate change produces a number of changes to the natural and built environments that may potentially increase respiratory disease prevalence, morbidity, and mortality. Nurses might consider focusing their research efforts on reducing the effects of greenhouse gases and in directing policy to mitigate the harmful effects of climate change. Nurses can also continue to direct educational and clinical actions to reduce risks for all populations, but most importantly, for our most vulnerable groups. While advancements have been made in understanding the impact of climate change on respiratory health, nurses can play an important role in reducing the deleterious effects of climate change. This will require a multipronged approach of research, policy, and clinical action. © 2017 Sigma Theta Tau International.

Young People Who Sexually Abuse: A Historical Perspective and Future Directions

ERIC Educational Resources Information Center

Rasmussen, Lucinda A.

2013-01-01

This article presents a historical overview of research on sexually abusive youth. The evolution of the field over the past 30 years is discussed--from the initial development of treatment interventions to contemporary efforts of professionals to move from traditional, adult-oriented interventions toward developmentally sensitive assessment…

False Premises, False Promises: The Mythical Character of Public Discourse about Education.

ERIC Educational Resources Information Center

Hawley, Willis D.

1985-01-01

Available research disproves a number of myths concerning educational quality, but the myths continue to influence educational reform efforts. The three categories of reform that could actually prove effective all affect teachers directly: salary raises, improved working conditions, and alterations in the professional structure of teaching. (PGD)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halvorson, C S

The FY09 budgets for homeland security research and development programs in the U.S. are summarized. Homeland security policy developments that can influence future efforts are discussed. Initial indications of the new administration direction on homeland security R&D are summarized. An overview of the Optics and Photonics in Global Homeland Security V conference is presented.

Core Competencies and the Prevention of High-Risk Sexual Behavior

ERIC Educational Resources Information Center

Charles, Vignetta Eugenia; Blum, Robert Wm.

2008-01-01

Adolescent sexual risk-taking behavior has numerous individual, family, community, and societal consequences. In an effort to contribute to the research and propose new directions, this chapter applies the core competencies framework to the prevention of high-risk sexual behavior. It describes the magnitude of the problem, summarizes explanatory…

Enterprise Line of Sight Analysis Using Evidential Reasoning

ERIC Educational Resources Information Center

Bunting, William J.

2012-01-01

The overall direction of this research is to improve the development of information systems within federal agency modernization efforts so that the systems produce a value to the federal agency that is significantly greater upon implementation than the investment required to develop the systems. Federal agencies are modernizing at an increasing…

Teaching Academic Vocabulary to Adolescents with Learning Disabilities

ERIC Educational Resources Information Center

Beach, Kristen D.; Sanchez, Victoria; Flynn, Lindsay J.; O'Connor, Rollanda E.

2015-01-01

This article describes the efforts of a U.S. History teacher to directly teach word meanings using the "robust vocabulary instruction" (RVI) approach, because research supports this method as a way to improve vocabulary knowledge for a range of students, including adolescents reading below grade level (i.e., struggling readers) and…

Mitigating Losses of Wetland Ecosystems: A Context for Evaluation.

ERIC Educational Resources Information Center

Mattingly, Rosanna L.

1994-01-01

Preservation of our wetlands has been an issue for many years. Today, despite current laws and those adopted 200 years ago, the wetlands remain insufficiently protected and developed. A holistic guide and suggestions for the classroom are provided to aid in efforts directed at wetland education, research and management. (ZWH)

Tree improvement research in oak species

Treesearch

Franklin C. Cech

1971-01-01

Early efforts at developing new forms of oak by interspecific hybridization have not been very successful, although spontaneous hybrids appear rather readily in nature. Preliminary reports on a few seed-source or provenance studies indicate that differences among sources are generally less than differences among trees within sources. This directs tree-improvement...

Smart molecules for imaging, sensing and health (SMITH).

PubMed

Smith, Bradley D

2015-01-01

This autobiographical review provides a personal account of the author's academic journey in supramolecular chemistry, including brief summaries of research efforts in membrane transport, molecular imaging, ion-pair receptors, rotaxane synthesis, squaraine rotaxanes, and synthtavidin technology. The article concludes with a short perspective of likely future directions in biomedical supramolecular chemistry.

Teaching as a Way of Knowing: Observing and Responding to Students' Abilities.

ERIC Educational Resources Information Center

Wansart, William L.

1995-01-01

This article describes action-oriented teacher research in which teachers use information students reveal about the competent aspects of their lives as learners to direct their teaching efforts. The article notes methodological considerations of this approach and applications to the study of special education. (Author/DB)

Integrated reclamation: Approaching ecological function?

Treesearch

Ann L. Hild; Nancy L. Shaw; Ginger B. Paige

2009-01-01

Attempts to reclaim arid and semiarid lands have traditionally targeted plant species composition. Much research attention has been directed to seeding rates, species mixes and timing of seeding. However, in order to attain functioning systems, attention to structure and process must compliment existing efforts. We ask how to use a systems approach to enhance...

College-Bound Communities. Lumina Foundation Focus™. Summer 2014

ERIC Educational Resources Information Center

Giegerich, Steve

2014-01-01

Research shows a direct correlation between thriving cities and high levels of college-level learning. Regions with robust levels of educational attainment have stronger economies, greater individual earning power, and better quality of life. The Lumina Foundation is actively supporting large-scale efforts in 55 metro regions--to help adults…

Storage root of cassava: Morphological types, anatomy, formation, growth, development and harvest time

USDA-ARS?s Scientific Manuscript database

Cassava (Manihot esculenta, Crantz) is considered a starchy root crop that provides staple food for millions of people in tropical and subtropical regions of the world. Research efforts are directed towards genetic breeding and cultivation of cassava to improve cassava storage root starch production...

Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) Project FY16 Annual Review

NASA Technical Reports Server (NTRS)

Grindle, Laurie; Hackenberg, Davis

2016-01-01

This presentation gives insight into the research activities and efforts being executed in order to integrate unmanned aircraft systems into the national airspace system. This briefing is to inform others of the UAS-NAS FY16 progress and future directions.

Making Time for Instructional Leadership. Appendices

ERIC Educational Resources Information Center

Goldring, Ellen; Grissom, Jason A.; Neumerski, Christine M.; Murphy, Joseph; Blissett, Richard; Porter, Andy

2015-01-01

This three-volume report describes the "SAM (School Administration Manager) process," an approach that about 700 schools around the nation are using to direct more of principals' time and effort to improve teaching and learning in classrooms. Research has shown that a principal's instructional leadership is second only to teaching among…

2002 NASA Faculty Fellowship Program at Glenn Research Center

NASA Technical Reports Server (NTRS)

Prahl, Joseph M.; Heyward, Ann O.; Montegani, Francis J.

2003-01-01

While several objectives are served with this program, the central mechanism involved is the conduct of research assignments by faculty in direct support of NASA programs. In general, the results of the research will be assimilated by NASA program managers into an overall effort and will ultimately find their way into the literature. Occasionally, specific assignments result directly in reports for publication or conference presentation. Taken as a body, the assignments represent a large intellectual contribution by the academic community to NASA programs. It is appropriate therefore to summarize the research that was accomplished. The remainder of this report consists of research summaries arranged alphabetically by participant name. For each summary, the faculty fellow is briefly identified and the assignment prepared by the GRC host organization is given. This is followed by a brief narrative, prepared by the fellow, of the research performed. Narratives provided by the accompanying students immediately follow the narratives of their professors.

Psychological research and global climate change

NASA Astrophysics Data System (ADS)

Clayton, Susan; Devine-Wright, Patrick; Stern, Paul C.; Whitmarsh, Lorraine; Carrico, Amanda; Steg, Linda; Swim, Janet; Bonnes, Mirilia

2015-07-01

Human behaviour is integral not only to causing global climate change but also to responding and adapting to it. Here, we argue that psychological research should inform efforts to address climate change, to avoid misunderstandings about human behaviour and motivations that can lead to ineffective or misguided policies. We review three key research areas: describing human perceptions of climate change; understanding and changing individual and household behaviour that drives climate change; and examining the human impacts of climate change and adaptation responses. Although much has been learned in these areas, we suggest important directions for further research.

Information management for commercial aviation - A research perspective

NASA Technical Reports Server (NTRS)

Ricks, Wendell R.; Abbott, Kathy H.; Jonsson, Jon E.; Boucek, George; Rogers, William H.

1991-01-01

The problem of flight deck information management (IM), defined as processing, controlling, and directing information, for commercial flight decks, and a research effort underway to address this problem, are discussed. The premises provided are utilized to lay the groundwork required for such research by providing a framework to describe IM problems and an avenue to follow when investigating solution concepts. The research issues presented serve to identify specific questions necessary to achieve a better understanding of the IM problem, and to provide assessments of the relative merit of various solution concepts.

NASA Langley Research and Technology-Transfer Program in Formal Methods

NASA Technical Reports Server (NTRS)

Butler, Ricky W.; Caldwell, James L.; Carreno, Victor A.; Holloway, C. Michael; Miner, Paul S.; DiVito, Ben L.

1995-01-01

This paper presents an overview of NASA Langley research program in formal methods. The major goals of this work are to make formal methods practical for use on life critical systems, and to orchestrate the transfer of this technology to U.S. industry through use of carefully designed demonstration projects. Several direct technology transfer efforts have been initiated that apply formal methods to critical subsystems of real aerospace computer systems. The research team consists of five NASA civil servants and contractors from Odyssey Research Associates, SRI International, and VIGYAN Inc.

Understanding NETCOM and Its Role in the 21st Century

DTIC Science & Technology

2007-03-30

information dominance goals that directly support transformation efforts. This project examines the reasons why NETCOM/9th ASC was created, reviews its unique organizational structure and mission, and outlines its role in the Army’s overarching transformation in the 21st century. Although the research reveals that NETCOM/9th ASC’s strategic plans and objectives are nested to support the Army’s transformation efforts, the lack of Army senior leader familiarity with this organization could put at risk some of the programs that support the implementation of its

Office of Biological and Physical Research: Overview Transitioning to the Vision for Space Exploration

NASA Technical Reports Server (NTRS)

Crouch, Roger

2004-01-01

Viewgraphs on NASA's transition to its vision for space exploration is presented. The topics include: 1) Strategic Directives Guiding the Human Support Technology Program; 2) Progressive Capabilities; 3) A Journey to Inspire, Innovate, and Discover; 4) Risk Mitigation Status Technology Readiness Level (TRL) and Countermeasures Readiness Level (CRL); 5) Biological And Physical Research Enterprise Aligning With The Vision For U.S. Space Exploration; 6) Critical Path Roadmap Reference Missions; 7) Rating Risks; 8) Current Critical Path Roadmap (Draft) Rating Risks: Human Health; 9) Current Critical Path Roadmap (Draft) Rating Risks: System Performance/Efficiency; 10) Biological And Physical Research Enterprise Efforts to Align With Vision For U.S. Space Exploration; 11) Aligning with the Vision: Exploration Research Areas of Emphasis; 12) Code U Efforts To Align With The Vision For U.S. Space Exploration; 13) Types of Critical Path Roadmap Risks; and 14) ISS Human Support Systems Research, Development, and Demonstration. A summary discussing the vision for U.S. space exploration is also provided.

Overview of the 1986 free-piston Stirling activities at NASA Lewis Research Center

NASA Technical Reports Server (NTRS)

Alger, Donald L.

1986-01-01

An overview of the NASA Lewis Research Center's free-piston Stirling engine research is presented, including efforts to improve and advance its design for use in specific space power applications. These efforts are a part of the SP-100 program being conducted to support the Department of Defense (DOD), Department of Energy (DOE) and NASA. Such efforts include: (1) the testing and improvement of 25 kWe Stirling Space Power Demonstrator Engine (SPDE); (2) the preliminary design of 25 kWe single-cylinder Experimental stirling Space Engine (ESSE); and, (3) a study to determine the feasibility of scaling a single-cylinder free-piston Stirling engine/linear alternator to 150 kWe. Other NASA Lewis free-piston Stirling engine activities will be described, directed toward the advancement of general free-piston Stirling engine technology and its application in specific terrestrial applications. One such effort, supported by DOE/Oak Ridge National Laboratory (DRNL), is the development of a free-piston Stirling engine which produces hydraulic power. Finally, a terrestrial solar application involving a conceptual design of a 25 kWe Solar Advanced Stirling Conversion System (ASCS) capable of delivering power to an electric utility grid will be discussed. The latter work is supported by DOE/Sandia National Laboratory (SNLA).

Nano-Bio-Genesis: tracing the rise of nanotechnology and nanobiotechnology as 'big science'

PubMed Central

Kulkarni, Rajan P

2007-01-01

Nanotechnology research has lately been of intense interest because of its perceived potential for many diverse fields of science. Nanotechnology's tools have found application in diverse fields, from biology to device physics. By the 1990s, there was a concerted effort in the United States to develop a national initiative to promote such research. The success of this effort led to a significant influx of resources and interest in nanotechnology and nanobiotechnology and to the establishment of centralized research programs and facilities. Further government initiatives (at federal, state, and local levels) have firmly cemented these disciplines as 'big science,' with efforts increasingly concentrated at select laboratories and centers. In many respects, these trends mirror certain changes in academic science over the past twenty years, with a greater emphasis on applied science and research that can be more directly utilized for commercial applications. We also compare the National Nanotechnology Initiative and its successors to the Human Genome Project, another large-scale, government funded initiative. These precedents made acceptance of shifts in nanotechnology easier for researchers to accept, as they followed trends already established within most fields of science. Finally, these trends are examined in the design of technologies for detection and treatment of cancer, through the Alliance for Nanotechnology in Cancer initiative of the National Cancer Institute. Federal funding of these nanotechnology initiatives has allowed for expansion into diverse fields and the impetus for expanding the scope of research of several fields, especially biomedicine, though the ultimate utility and impact of all these efforts remains to be seen. PMID:17629932

Development of a Direct Evaporator for the Organic Rankine Cycle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Donna Post Guillen; Helge Klockow; Matthew Lehar

2011-02-01

This paper describes research and development currently underway to place the evaporator of an Organic Rankine Cycle (ORC) system directly in the path of a hot exhaust stream produced by a gas turbine engine. The main goal of this research effort is to improve cycle efficiency and cost by eliminating the usual secondary heat transfer loop. The project’s technical objective is to eliminate the pumps, heat exchangers and all other added cost and complexity of the secondary loop by developing an evaporator that resides in the waste heat stream, yet virtually eliminates the risk of a working fluid leakage intomore » the gaseous exhaust stream. The research team comprised of Idaho National Laboratory and General Electric Company engineers leverages previous research in advanced ORC technology to develop a new direct evaporator design that will reduce the ORC system cost by up to 15%, enabling the rapid adoption of ORCs for waste heat recovery.« less

Analyzing the contributions of a government-commissioned research project: a case study.

PubMed

Hegger, Ingrid; Janssen, Susan W J; Keijsers, Jolanda F E M; Schuit, Albertine J; van Oers, Hans A M

2014-02-05

It often remains unclear to investigators how their research contributes to the work of the commissioner. We initiated the 'Risk Model' case study to gain insight into how a Dutch National Institute for Public Health and the Environment (RIVM) project and its knowledge products contribute to the commissioner's work, the commissioner being the Health Care Inspectorate. We aimed to identify the alignment efforts that influenced the research project contributions. Based on the literature, we expected interaction between investigators and key users to be the most determining factor for the contributions of a research project. In this qualitative case study, we analyzed the alignment efforts and contributions in the Risk Model project by means of document analysis and interviews according to the evaluation method Contribution Mapping. Furthermore, a map of the research process was drafted and a feedback session was organized. After the feedback session with stakeholders discussing the findings, we completed the case study report. Both organizations had divergent views on the ownership of the research product and the relationship between RIVM and the Inspectorate, which resulted in different expectations. The RIVM considered the use of the risk models to be problematic, but the inspectors had a positive opinion about its contributions. Investigators, inspectors, and managers were not aware of these remarkably different perceptions. In this research project, we identified six relevant categories of both horizontal alignment efforts (between investigators and key users) as well as vertical alignment efforts (within own organization) that influenced the contributions to the Inspectorate's work. Relevant alignment efforts influencing the contributions of the project became manifest at three levels: the first level directly relates to the project, the second to the organizational environment, and the third to the formal and historical relationship between the organizations. Both external and internal alignments influence the contributions of a research project. Based on the findings, we recommend that research institutes invest in a reflective attitude towards the social aspects of research projects at all levels of the organization and develop alignment strategies to enhance the contributions of research.

Analyzing the contributions of a government-commissioned research project: a case study

PubMed Central

2014-01-01

Background It often remains unclear to investigators how their research contributes to the work of the commissioner. We initiated the ‘Risk Model’ case study to gain insight into how a Dutch National Institute for Public Health and the Environment (RIVM) project and its knowledge products contribute to the commissioner’s work, the commissioner being the Health Care Inspectorate. We aimed to identify the alignment efforts that influenced the research project contributions. Based on the literature, we expected interaction between investigators and key users to be the most determining factor for the contributions of a research project. Methods In this qualitative case study, we analyzed the alignment efforts and contributions in the Risk Model project by means of document analysis and interviews according to the evaluation method Contribution Mapping. Furthermore, a map of the research process was drafted and a feedback session was organized. After the feedback session with stakeholders discussing the findings, we completed the case study report. Results Both organizations had divergent views on the ownership of the research product and the relationship between RIVM and the Inspectorate, which resulted in different expectations. The RIVM considered the use of the risk models to be problematic, but the inspectors had a positive opinion about its contributions. Investigators, inspectors, and managers were not aware of these remarkably different perceptions. In this research project, we identified six relevant categories of both horizontal alignment efforts (between investigators and key users) as well as vertical alignment efforts (within own organization) that influenced the contributions to the Inspectorate’s work. Conclusions Relevant alignment efforts influencing the contributions of the project became manifest at three levels: the first level directly relates to the project, the second to the organizational environment, and the third to the formal and historical relationship between the organizations. Both external and internal alignments influence the contributions of a research project. Based on the findings, we recommend that research institutes invest in a reflective attitude towards the social aspects of research projects at all levels of the organization and develop alignment strategies to enhance the contributions of research. PMID:24498894

Societal views and animal welfare science: understanding why the modified cage may fail and other stories.

PubMed

Weary, D M; Ventura, B A; von Keyserlingk, M A G

2016-02-01

The innovations developed by scientists working on animal welfare are often not adopted in practice. In this paper, we argue that one important reason for this failure is that the solutions proposed do not adequately address the societal concerns that motivated the original research. Some solutions also fail because they do not adequately address perceived constraints within the industry. Using examples from our own recent work, we show how research methods from the social sciences can address both of these limitations. For example, those who persist in tail-docking cattle (despite an abundance of evidence showing that the practice has no benefits) often justify their position by citing concern for cow cleanliness. This result informs the nature of new extension efforts directed at farmers that continue to tail dock, suggesting that these efforts will be more effective if they focus on providing producers with methods (of proven efficacy) for keeping cows clean. Work on pain mitigation for dehorning shows that some participants reluctant to provide pain relief believe that the pain from this procedure is short lasting and has little impact on the calf. This result informs the direction of new biological research efforts to understand both the magnitude and duration of any suffering that result from this type of procedure. These, and other examples, illustrate how social science methodologies can document the shared and divergent values of different stakeholders (to ensure that proposed solutions align with mainstream values), beliefs regarding the available evidence (to help target new scientific research that meets the perceived gaps), and barriers in implementing changes (to ease adoption of ideas by addressing these barriers).

Characteristics and Use of a Parametric End-Fired Array for Acoustics in Air

DTIC Science & Technology

2007-03-01

as a sonar application for underwater use. The vast majority of the research for parametric arrays was devoted to underwater applications until the...and also for the calibration of hydrophones and receivers for wide band sonar . All of the researchers mentioned above mainly focused their efforts on...features, which include very high directivity at low frequencies without unwanted side lobes. They are generally used as a wide band sonar system

Neural control of arm movements reveals a tendency to use gravity to simplify joint coordination rather than to decrease muscle effort.

PubMed

Wang, Wanyue; Dounskaia, Natalia

2016-12-17

How gravity influences neural control of arm movements remains under debate. We tested three alternative interpretations suggested by previous research: (1) that muscular control includes two components, tonic which compensates for gravity and phasic which produces the movement; (2) that there is a tendency to exploit gravity to reduce muscle effort; and (3) that there is a tendency to use a trailing pattern of joint control during which either the shoulder or elbow is rotated actively and the other joint rotates predominantly passively, and to exploit gravity for control of the passively rotated joint. A free-stroke drawing task was performed that required production of center-out strokes within a circle while selecting stroke directions randomly. The circle was positioned in the horizontal, sagittal, and frontal plane. The arm joints freely rotated in space. In each plane, the distribution of the strokes across directions was non-uniform. Directional histograms were built and their peaks were used to identify preferred movement directions. The directional preferences were especially pronounced in the two vertical planes. The upward directions were most preferred. To test the three interpretations, we used a kinetic analysis that determined the role of gravitational torque in the production of movement in the preferred directions. The results supported the third interpretation and provided evidence against the first and second interpretation. The trailing pattern has been associated with reduced neural effort for joint coordination, and therefore, we conclude that the major tendency with respect to gravity is to exploit it for simplification of joint coordination. Copyright © 2016 IBRO. Published by Elsevier Ltd. All rights reserved.

Directions for the International Society for Research on Internet Interventions (ISRII)

PubMed Central

Andersson, Gerhard; Christensen, Helen M; Carlbring, Per; Cuijpers, Pim

2006-01-01

In 2004, the International Society for Research on Internet Interventions (ISRII) was formed to encourage eHealth researchers to collaborate in their efforts to further the science behind developing, testing, and disseminating Web-based treatment programs. The group held its second meeting (April 2006) to clarify the Society’s direction and identify key issues that need addressing in the field. These issues are identified and examined in the current paper. Given the success of using the Internet to treat a range of medical and mental health problems, and the growing need for better dissemination of health care, Internet interventions will almost certainly play a prominent role in global health. ISRII plans to provide the necessary venue to ensure the science driving this field is strong, enabling researchers to conduct the highest quality research and permitting meaningful conclusions from completed studies. PMID:17032639

PHASE II CALDERON PROCESS TO PRODUCE DIRECT REDUCED IRON RESEARCH AND DEVELOPMENT PROJECT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Albert Calderon

2003-04-28

This project was initially targeted to the making of coke for blast furnaces by using proprietary technology of Calderon in a phased approach, and Phase I was successfully completed. The project was then re-directed to the making of iron units. U.S. Steel teamed up with Calderon for a joint effort which will last 30 months to produce directly reduced iron with the potential of converting it into molten iron or steel consistent with the Roadmap recommendations of 1998 prepared by the Steel Industry in cooperation with the Department of Energy.

PHASE II CALDERON PROCESS TO PRODUCE DIRECT REDUCED IRON RESEARCH AND DEVELOPMENT PROJECT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Albert Calderon

2003-01-28

This project was initially targeted to the making of coke for blast furnaces by using proprietary technology of Calderon in a phased approach, and Phase I was successfully completed. The project was then re-directed to the making of iron units. U.S. Steel teamed up with Calderon for a joint effort which will last 30 months to produce directly reduced iron with the potential of converting it into molten iron or steel consistent with the Roadmap recommendations of 1998 prepared by the Steel Industry in cooperation with the Department of Energy.

KSC-02pd0616

NASA Image and Video Library

2002-04-29

KENNEDY SPACE CENTER, FLA. -- The Honorable Diana Morgan speaks to attendees at the opening ceremony kicking off a new program known as SABRE, Space Agricultural Biotechnology Research and Education. In the foreground are Center Director Roy D. Bridges Jr. (left) and U.S. Representative Dave Weldon (right). The SABRE program is a combined effort of the University of Florida and NASA. Morgan is vice chair on the UF Board of Trustees. SABRE will focus on the discovery, development and application of the biological aspects of advanced life support strategies. The program will include faculty from UF's Institute of Food and Agricultural Sciences, who will be located at both KSC - in the state-owned Space Experiment Research and Processing Laboratory (SERPL) being built there - and UF in Gainesville. SABRE will be directed by Robert Ferl, professor in the horticultural sciences department and assistant director of UF's Biotechnology Program. He will be responsible for coordinating the research and education efforts of UF and NASA

Neurotech for Neuroscience: Unifying Concepts, Organizing Principles, and Emerging Tools

PubMed Central

Silver, Rae; Boahen, Kwabena; Grillner, Sten; Kopell, Nancy; Olsen, Kathie L.

2012-01-01

The ability to tackle analysis of the brain at multiple levels simultaneously is emerging from rapid methodological developments. The classical research strategies of “measure,” “model,” and “make” are being applied to the exploration of nervous system function. These include novel conceptual and theoretical approaches, creative use of mathematical modeling, and attempts to build brain-like devices and systems, as well as other developments including instrumentation and statistical modeling (not covered here). Increasingly, these efforts require teams of scientists from a variety of traditional scientific disciplines to work together. The potential of such efforts for understanding directed motor movement, emergence of cognitive function from neuronal activity, and development of neuromimetic computers are described by a team that includes individuals experienced in behavior and neuroscience, mathematics, and engineering. Funding agencies, including the National Science Foundation, explore the potential of these changing frontiers of research for developing research policies and long-term planning. PMID:17978017

Overview of NRC Proactive Management of Materials Degradation (PMMD) Program

NASA Astrophysics Data System (ADS)

Carpenter, C. E. Gene; Hull, Amy; Oberson, Greg

Materials degradation phenomena, if not appropriately managed, have the potential to adversely impact the design functionality and safety margins of nuclear power plant (NPP) systems, structures and components (SSCs). Therefore, the U.S. Nuclear Regulatory Commission (NRC) has initiated an over-the-horizon multi-year research Proactive Management of Materials Degradation (PMMD) Research Program, which is presently evaluating longer time frames (i.e., 80 or more years) and including passive long-lived SSCs beyond the primary piping and core internals, such as concrete containment and cable insulation. This will allow the NRC to (1) identify significant knowledge gaps and new forms of degradation; (2) capture current knowledge base; and, (3) prioritize materials degradation research needs and directions for future efforts. This effort is being accomplished in collaboration with the U.S. Department of Energy's (DOE) LWR Sustainability (LWRS) program. This presentation will discuss the activities to date, including results, and the path forward.

Development and Evaluation of Educational Programs in Electromechanical Technology. Final Report.

ERIC Educational Resources Information Center

Roney, M. W.

The encompassing objective of this project was to assist two-year colleges in establishing electromechanical technican (EMT) training programs by developing the necessary planning and instructional materials and by providing direct program planning assistance. The research effort of the project was to develop and test an integrated systems of…

Partner Enabling of Substance Use Disorders: Critical Review and Future Directions.

ERIC Educational Resources Information Center

Rotunda, Rob J.; Doman, Kathy

2001-01-01

Substance use disorders affect not only the identified client but significant others as well. This article contrasts the enabling and codependency constructs, reviews empirical studies of enabling, and offers a conceptualization of partner responses to addiction that could enhance future research efforts and clinical applications in this area. (BF)

Acceptance versus Change in Behavior Therapy: An Interview with Neil Jacobson.

ERIC Educational Resources Information Center

Hines, Max

1998-01-01

Neil Jacobson is a leader in research-based efforts to improve behavioral couples therapy. This interview focuses on his professional journey toward an integrative model, as well as his thoughts about the future directions of behavioral therapy and family counseling. The integrative-couples therapy model is described and discussed. (Author/EMK)

75 FR 6697 - Endangered and Threatened Wildlife and Plants; Draft Yuma Clapper Rail (Rallus longirostris...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

...-term contracts for water supplies at Sonny Bono Salton Sea National Wildlife Refuge and Imperial State... species is completed and protective measures implemented if needed; and a secure water supply for the..., directed research on habitat and threats, efforts to obtain secure water supplies for important habitats...

Sourcebook on Food and Nutrition. Third Edition.

ERIC Educational Resources Information Center

Scarpa, Ioannis S., Ed.; And Others

This four-part book is a compendium of current dietary information and is designed primarily as a reference tool for anyone interested in the field of nutrition. The book's first three parts each contain papers generated from nutrition-related research. Part 1, "Dietary Directions in the 1980s," begins by discussing efforts of major governmental…

Severity Levels and Symptoms Complexes for Acute Radiation Sickness -- Description and Quantification

DTIC Science & Technology

1985-11-30

of military task performance levels. This effort was performed under the guidance and direction of DNA staff members Dr. David Auton and Dr. Robert W...INC ATTN: J HOWE ATTN: S SHRIER HORIZONS TECHNOLOGY, INC S-CUBEDATTN: B PYATT ATTN: J PALMER I:T RESEARCH INSTITUTE SCIENCE APPLICATIONS INTL CORP

Students' Epistemologies about Experimental Physics: Validating the Colorado Learning Attitudes about Science Survey for Experimental Physics

ERIC Educational Resources Information Center

Wilcox, Bethany R.; Lewandowski, H. J.

2016-01-01

Student learning in instructional physics labs represents a growing area of research that includes investigations of students' beliefs and expectations about the nature of experimental physics. To directly probe students' epistemologies about experimental physics and support broader lab transformation efforts at the University of Colorado Boulder…

The ARL Scholars Portal Initiative.

ERIC Educational Resources Information Center

Jackson, Mary E.

2002-01-01

Describes an initiative of the Association of Research Libraries (ARL), the Scholars Portal Initiative, a three-year collaborative effort which seeks to provide tools for an academic community to have a single point of access on the Web to find high-quality information resources and to deliver the information and related services directly to the…

State-of-the-art developments in the field of electroactive polymers

NASA Technical Reports Server (NTRS)

Vinogradov, Aleksandra; Su, Ji; Jenkins, Christopher; Bar-Cohen, Yoseph

2005-01-01

The paper presents a brief review in the field of electroactive polymers. it outlines the main classes of electroactive polymers, their properties and applications. Current efforts to synthesize electroactive polymers with novel or improved characteristics along with the challenges, opportunities and future research directions in the subject area are discussed.

Unifying Different Theories of Learning: Theoretical Framework and Empirical Evidence

ERIC Educational Resources Information Center

Phan, Huy Phuong

2008-01-01

The main aim of this research study was to test out a conceptual model encompassing the theoretical frameworks of achievement goals, study processing strategies, effort, and reflective thinking practice. In particular, it was postulated that the causal influences of achievement goals on academic performance are direct and indirect through study…

Innovation, Corporate Strategy, and Cultural Context: What Is the Mission for International Business Communication?

ERIC Educational Resources Information Center

Ulijn, Jan; O'Hair, Dan; Weggeman, Mathieu; Ledlow, Gerald; Hall, H. Thomas

2000-01-01

Reviews relevant literature in the areas of communication and innovation and explores how efforts toward innovative practices are directly related to globalism and business strategy. Focuses on issues associated with national culture, corporate culture, and professional culture that are relevant to strategies for researching business communication…

PATTERNS OF MASTERY AND CONFLICT RESOLUTION AT THE ELEMENTARY SCHOOL LEVEL.

ERIC Educational Resources Information Center

MINUCHIN, PATRICIA; AND OTHERS

EFFORTS WERE DIRECTED TOWARD THE EXPLORATION OF CONNECTIONS BETWEEN THE HOME AND SCHOOL BACKGROUND INFLUENCES OF FOURTH-GRADE CHILDREN, AND THE PATTERNS OF RESPONSE THROUGH WHICH CHILDREN MASTER CHALLENGE, REACT TO OPPORTUNITY, AND EXPRESS AND HANDLE CONFLICT. THIS CURRENT RESEARCH WAS BUILT UPON AN EARLIER STUDY WHICH ASSESSED THE EFFECTS OF…

Making Educational Reform Work: Stories of School Improvement in Urban China

ERIC Educational Resources Information Center

Hamilton, Doug

2014-01-01

The latest national educational policy in the People's Republic of China calls for comprehensive educational reforms aimed at building the foundation for a modern learning society throughout China over the next 10 years. This research examines school leaders' efforts to implement school improvement initiatives that directly respond to the policy's…

Making Time for Instructional Leadership. Volume 1: Executive Summary

ERIC Educational Resources Information Center

Goldring, Ellen; Grissom, Jason A.; Neumerski, Christine M.; Murphy, Joseph; Blissett, Richard; Porter, Andy

2015-01-01

This three-volume report describes the "SAM (School Administration Manager) process," an approach that about 700 schools around the nation are using to direct more of principals' time and effort to improve teaching and learning in classrooms. Research has shown that a principal's instructional leadership is second only to teaching among…

Black Men and the Struggle for Work: Social and Economic Barriers Persist

ERIC Educational Resources Information Center

Quane, James M.; Wilson, William Julius; Hwang, Jackelyn

2015-01-01

This article looks at some of the issues presented in a 1965 study that remain to date regarding economic disadvantage and family instability. Research undertaken since that time has reinforced the need for more coordinated, government-directed efforts to dismantle structures that reinforce racial and class-based biases and inequalities. The…

Intellectual Disability and Developmental Risk: Promoting Intervention to Improve Child and Family Well-Being

ERIC Educational Resources Information Center

Crnic, Keith A.; Neece, Cameron L.; McIntyre, Laura Lee; Blacher, Jan; Baker, Bruce L.

2017-01-01

Initial intervention processes for children with intellectual disabilities (IDs) largely focused on direct efforts to impact core cognitive and academic deficits associated with the diagnosis. Recent research on risk processes in families of children with ID, however, has influenced new developmental system approaches to early intervention. Recent…

Youth tobacco prevention mass media campaigns: past, present, and future directions.

PubMed

Farrelly, M C; Niederdeppe, J; Yarsevich, J

2003-06-01

This paper focuses on countermarketing efforts aimed at curbing youth smoking. We review the literature on the effectiveness of tobacco countermarketing campaigns, characterise current state and national campaign approaches, present findings from qualitative approaches and laboratory experiments that explore a variety of messages (for example, health consequences, industry manipulation), and discuss newer, non-traditional approaches to countermarketing. In conclusion, we outline research needed to fill gaps in our existing knowledge and discuss future directions in tobacco countermarketing aimed at youth.

National Institutes of Health Update: Translating Basic Behavioral Science into New Pediatric Obesity Interventions.

PubMed

Czajkowski, Susan M

2016-06-01

Pediatric obesity increases the risk of later-life obesity and chronic diseases. Basic research to better understand factors associated with excessive weight gain in early life and studies translating research findings into preventive and therapeutic strategies are essential to our ability to better prevent and treat childhood obesity. This overview describes several National Institutes of Health efforts designed to stimulate basic and translational research in childhood obesity prevention and treatment. These examples demonstrate the value of research in early phase translational pediatric obesity research and highlight some promising directions for this important area of research. Published by Elsevier Inc.

Hydrodynamic Analyses and Evaluation of New Fluid Film Bearing Concepts

NASA Technical Reports Server (NTRS)

Keith, Theo G., Jr.; Dimofte, Florin

1998-01-01

Over the past several years, numerical and experimental investigations have been performed on a waved journal bearing. The research work was undertaken by Dr. Florin Dimofte, a Senior Research Associate in the Mechanical Engineering Department at the University of Toledo. Dr. Theo Keith, Distinguished University Professor in the Mechanical Engineering Department was the Technical Coordinator of the project. The wave journal bearing is a bearing with a slight but precise variation in its circular profile such that a waved profile is circumscribed on the inner bearing diameter. The profile has a wave amplitude that is equal to a fraction of the bearing clearance. Prior to this period of research on the wave bearing, computer codes were written and an experimental facility was established. During this period of research considerable effort was directed towards the study of the bearing's stability. The previously developed computer codes and the experimental facility were of critical importance in performing this stability research. A collection of papers and reports were written to describe the results of this work. The attached captures that effort and represents the research output during the grant period.

Future Directions in Idiopathic Pulmonary Fibrosis Research. An NHLBI Workshop Report

PubMed Central

Blackwell, Timothy S.; Tager, Andrew M.; Borok, Zea; Moore, Bethany B.; Schwartz, David A.; Anstrom, Kevin J.; Bar-Joseph, Ziv; Bitterman, Peter; Blackburn, Michael R.; Bradford, William; Brown, Kevin K.; Chapman, Harold A.; Collard, Harold R.; Cosgrove, Gregory P.; Deterding, Robin; Doyle, Ramona; Flaherty, Kevin R.; Garcia, Christine Kim; Hagood, James S.; Henke, Craig A.; Herzog, Erica; Hogaboam, Cory M.; Horowitz, Jeffrey C.; King, Talmadge E.; Loyd, James E.; Lawson, William E.; Marsh, Clay B.; Noble, Paul W.; Noth, Imre; Sheppard, Dean; Olsson, Julie; Ortiz, Luis A.; O’Riordan, Thomas G.; Oury, Tim D.; Raghu, Ganesh; Roman, Jesse; Sime, Patricia J.; Sisson, Thomas H.; Tschumperlin, Daniel; Violette, Shelia M.; Weaver, Timothy E.; Wells, Rebecca G.; White, Eric S.; Kaminski, Naftali; Martinez, Fernando J.; Wynn, Thomas A.; Thannickal, Victor J.

2014-01-01

The median survival of patients with idiopathic pulmonary fibrosis (IPF) continues to be approximately 3 years from the time of diagnosis, underscoring the lack of effective medical therapies for this disease. In the United States alone, approximately 40,000 patients die of this disease annually. In November 2012, the NHLBI held a workshop aimed at coordinating research efforts and accelerating the development of IPF therapies. Basic, translational, and clinical researchers gathered with representatives from the NHLBI, patient advocacy groups, pharmaceutical companies, and the U.S. Food and Drug Administration to review the current state of IPF research and identify priority areas, opportunities for collaborations, and directions for future research. The workshop was organized into groups that were tasked with assessing and making recommendations to promote progress in one of the following six critical areas of research: (1) biology of alveolar epithelial injury and aberrant repair; (2) role of extracellular matrix; (3) preclinical modeling; (4) role of inflammation and immunity; (5) genetic, epigenetic, and environmental determinants; (6) translation of discoveries into diagnostics and therapeutics. The workshop recommendations provide a basis for directing future research and strategic planning by scientific, professional, and patient communities and the NHLBI. PMID:24160862

Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.

PubMed

Blackwell, Timothy S; Tager, Andrew M; Borok, Zea; Moore, Bethany B; Schwartz, David A; Anstrom, Kevin J; Bar-Joseph, Ziv; Bitterman, Peter; Blackburn, Michael R; Bradford, William; Brown, Kevin K; Chapman, Harold A; Collard, Harold R; Cosgrove, Gregory P; Deterding, Robin; Doyle, Ramona; Flaherty, Kevin R; Garcia, Christine Kim; Hagood, James S; Henke, Craig A; Herzog, Erica; Hogaboam, Cory M; Horowitz, Jeffrey C; King, Talmadge E; Loyd, James E; Lawson, William E; Marsh, Clay B; Noble, Paul W; Noth, Imre; Sheppard, Dean; Olsson, Julie; Ortiz, Luis A; O'Riordan, Thomas G; Oury, Tim D; Raghu, Ganesh; Roman, Jesse; Sime, Patricia J; Sisson, Thomas H; Tschumperlin, Daniel; Violette, Shelia M; Weaver, Timothy E; Wells, Rebecca G; White, Eric S; Kaminski, Naftali; Martinez, Fernando J; Wynn, Thomas A; Thannickal, Victor J; Eu, Jerry P

2014-01-15

The median survival of patients with idiopathic pulmonary fibrosis (IPF) continues to be approximately 3 years from the time of diagnosis, underscoring the lack of effective medical therapies for this disease. In the United States alone, approximately 40,000 patients die of this disease annually. In November 2012, the NHLBI held a workshop aimed at coordinating research efforts and accelerating the development of IPF therapies. Basic, translational, and clinical researchers gathered with representatives from the NHLBI, patient advocacy groups, pharmaceutical companies, and the U.S. Food and Drug Administration to review the current state of IPF research and identify priority areas, opportunities for collaborations, and directions for future research. The workshop was organized into groups that were tasked with assessing and making recommendations to promote progress in one of the following six critical areas of research: (1) biology of alveolar epithelial injury and aberrant repair; (2) role of extracellular matrix; (3) preclinical modeling; (4) role of inflammation and immunity; (5) genetic, epigenetic, and environmental determinants; (6) translation of discoveries into diagnostics and therapeutics. The workshop recommendations provide a basis for directing future research and strategic planning by scientific, professional, and patient communities and the NHLBI.

Diffusion of Energy Efficient Technology in Commercial Buildings: An Analysis of the Commercial Building Partnerships Program

NASA Astrophysics Data System (ADS)

Antonopoulos, Chrissi Argyro

This study presents findings from survey and interview data investigating replication of green building measures by Commercial Building Partnership (CBP) partners that worked directly with the Pacific Northwest National Laboratory (PNNL). PNNL partnered directly with 12 organizations on new and retrofit construction projects, which represented approximately 28 percent of the entire U.S. Department of Energy (DOE) CBP program. Through a feedback survey mechanism, along with personal interviews, quantitative and qualitative data were gathered relating to replication efforts by each organization. These data were analyzed to provide insight into two primary research areas: 1) CBP partners' replication efforts of green building approaches used in the CBP project to the rest of the organization's building portfolio, and, 2) the market potential for technology diffusion into the total U.S. commercial building stock, as a direct result of the CBP program. The first area of this research focused specifically on replication efforts underway or planned by each CBP program participant. The second area of this research develops a diffusion of innovations model to analyze potential broad market impacts of the CBP program on the commercial building industry in the United States. Findings from this study provided insight into motivations and objectives CBP partners had for program participation. Factors that impact replication include motivation, organizational structure and objectives firms have for implementation of energy efficient technologies. Comparing these factors between different CBP partners revealed patterns in motivation for constructing energy efficient buildings, along with better insight into market trends for green building practices. The optimized approach to the CBP program allows partners to develop green building parameters that fit the specific uses of their building, resulting in greater motivation for replication. In addition, the diffusion model developed for this analysis indicates that this method of market prediction may be used to adequately capture cumulative construction metrics for a whole-building analysis as opposed to individual energy efficiency measures used in green building.

Aerodynamics of advanced axial-flow turbomachinery

NASA Technical Reports Server (NTRS)

Serovy, G. K.; Kavanagh, P.; Kiishi, T. H.

1980-01-01

A multi-task research program on aerodynamic problems in advanced axial-flow turbomachine configurations was carried out at Iowa State University. The elements of this program were intended to contribute directly to the improvement of compressor, fan, and turbine design methods. Experimental efforts in intra-passage flow pattern measurements, unsteady blade row interaction, and control of secondary flow are included, along with computational work on inviscid-viscous interaction blade passage flow techniques. This final report summarizes the results of this program and indicates directions which might be taken in following up these results in future work. In a separate task a study was made of existing turbomachinery research programs and facilities in universities located in the United States. Some potentially significant research topics are discussed which might be successfully attacked in the university atmosphere.

A Research Agenda to Underpin Malaria Eradication

PubMed Central

Alonso, Pedro L.; Brown, Graham; Arevalo-Herrera, Myriam; Binka, Fred; Chitnis, Chetan; Collins, Frank; Doumbo, Ogobara K.; Greenwood, Brian; Hall, B. Fenton; Levine, Myron M.; Mendis, Kamini; Newman, Robert D.; Plowe, Christopher V.; Rodríguez, Mario Henry; Sinden, Robert; Slutsker, Laurence; Tanner, Marcel

2011-01-01

The interruption of malaria transmission worldwide is one of the greatest challenges for international health and development communities. The current expert view suggests that, by aggressively scaling up control with currently available tools and strategies, much greater gains could be achieved against malaria, including elimination from a number of countries and regions; however, even with maximal effort we will fall short of global eradication. The Malaria Eradication Research Agenda (malERA) complements the current research agenda—primarily directed towards reducing morbidity and mortality—with one that aims to identify key knowledge gaps and define the strategies and tools that will result in reducing the basic reproduction rate to less than 1, with the ultimate aim of eradication of the parasite from the human population. Sustained commitment from local communities, civil society, policy leaders, and the scientific community, together with a massive effort to build a strong base of researchers from the endemic areas will be critical factors in the success of this new agenda. PMID:21311579

The Incident Command System: a literature review.

PubMed

Jensen, Jessica; Thompson, Steven

2016-01-01

Given the foundational and the fundamental role that the Incident Command System (ICS) is intended to play in on-scene response efforts across the United States, it is important to determine what is known about the system and how this is known. Accordingly, this study addresses the following research question: 'How has research explored the ICS?'. To probe this question, a methodological review of the scant, but widening, pool of research literature directly related to the ICS was conducted. This paper reports on the findings of the analysis related to the focus, theoretical frameworks, population and sampling, methods, results, and conclusions of the existing research literature. While undertaken using different methodological approaches, the ICS research suggests that the system may be limited in its usefulness. In addition, the paper discusses the implications of the research for the state of knowledge of the system and for the direction of future research. © 2016 The Author(s). Disasters © Overseas Development Institute, 2016.

Evolution of Aging Theories: Why Modern Programmed Aging Concepts Are Transforming Medical Research.

PubMed

Goldsmith, Theodore C

2016-12-01

Programmed aging refers to the idea that senescence in humans and other organisms is purposely caused by evolved biological mechanisms to obtain an evolutionary advantage. Until recently, programmed aging was considered theoretically impossible because of the mechanics of the evolution process, and medical research was based on the idea that aging was not programmed. Theorists struggled for more than a century in efforts to develop non-programmed theories that fit observations, without obtaining a consensus supporting any non-programmed theory. Empirical evidence of programmed lifespan limitations continued to accumulate. More recently, developments, especially in our understanding of biological inheritance, have exposed major issues and complexities regarding the process of evolution, some of which explicitly enable programmed aging of mammals. Consequently, science-based opposition to programmed aging has dramatically declined. This progression has major implications for medical research, because the theories suggest that very different biological mechanisms are ultimately responsible for highly age-related diseases that now represent most research efforts and health costs. Most particularly, programmed theories suggest that aging per se is a treatable condition and suggest a second path toward treating and preventing age-related diseases that can be exploited in addition to the traditional disease-specific approaches. The theories also make predictions regarding the nature of biological aging mechanisms and therefore suggest research directions. This article discusses developments of evolutionary mechanics, the consequent programmed aging theories, and logical inferences concerning biological aging mechanisms. It concludes that major medical research organizations cannot afford to ignore programmed aging concepts in assigning research resources and directions.

Nd:YAG Laser-Based Dual-Line Detection Rayleigh Scattering and Current Efforts on UV, Filtered Rayleigh Scattering

NASA Technical Reports Server (NTRS)

Otugen, M. Volkan; Popovic, Svetozar

1996-01-01

Ongoing research in Rayleigh scattering diagnostics for variable density low speed flow applications and for supersonic flow measurements are described. During the past several years, the focus has been on the development and use of a Nd:YAG-based Rayleigh scattering system with improved signal-to-noise characteristics and with applicability to complex, confined flows. This activity serves other research projects in the Aerodynamics Laboratory which require the non-contact, accurate, time-frozen measurement of gas density, pressure, and temperature (each separately), in a fairly wide dynamic range of each parameter. Recently, with the acquisition of a new seed-injected Nd:YAG laser, effort also has been directed to the development of a high-speed velocity probe based on a spectrally resolved Rayleigh scattering technique.

On Achieving Transdisciplinary Outcomes from Synergistic Research Efforts in the Northern Gulf of Mexico

NASA Astrophysics Data System (ADS)

Hagen, S. C.

2017-12-01

Multiple federal initiatives aim to evaluate and enhance sustainability and resilience at the coastal-land margin. Progressive efforts undertaken in the northern Gulf of Mexico for more than ten years have resulted in synergistic research with multiple means of federal support. Major grants include the FEMA Flood Insurance Studies, the NOAA / NOS Ecological Effects of Sea Level Rise Program, as well as the NSF Coastal SEES Program. Through a careful development of a collective enterprise the results from these and other individual programs (e.g., NOAA Sea Grant College, DHS Center of Excellence, NSF Rapid Response) have been elevated to achieve transdisciplinary outcomes. A direct product of the synergy is a system of systems approach to bio-geophysical science with the inclusion of socioeconomic processes.

ECR plasma thruster research - Preliminary theory and experiments

NASA Technical Reports Server (NTRS)

Sercel, Joel C.; Fitzgerald, Dennis J.

1989-01-01

A preliminary theory of the operation of the electron-cyclotron-resonance (ECR) plasma thruster is described along with an outline of recent experiments. This work is presented to communicate the status of an ongoing research effort directed at developing a unified theory to quantitatively describe the operation of the ECR plasma thruster. The theory is presented as a set of nonlinear ordinary differential equations and boundary conditions which describe the plasma density, velocity, and electron temperature. Diagnostic tools developed to measure plasma conditions in the existing research device are described.

Historical perspectives - The role of the NASA Lewis Research Center in the national space nuclear power programs

NASA Technical Reports Server (NTRS)

Bloomfield, H. S.; Sovie, R. J.

1991-01-01

The history of the NASA Lewis Research Center's role in space nuclear power programs is reviewed. Lewis has provided leadership in research, development, and the advancement of space power and propulsion systems. Lewis' pioneering efforts in nuclear reactor technology, shielding, high temperature materials, fluid dynamics, heat transfer, mechanical and direct energy conversion, high-energy propellants, electric propulsion and high performance rocket fuels and nozzles have led to significant technical and management roles in many natural space nuclear power and propulsion programs.

Advanced CO 2 Leakage Mitigation using Engineered Biomineralization Sealing Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spangler, Lee; Cunningham, Alfred; Phillips, Adrienne

2015-03-31

This research project addresses one of the goals of the DOE Carbon Sequestration Program (CSP). The CSP core R&D effort is driven by technology and is accomplished through laboratory and pilot scale research aimed at new technologies for greenhouse gas mitigation. Accordingly, this project was directed at developing novel technologies for mitigating unwanted upward leakage of carbon dioxide (CO 2) injected into the subsurface as part of carbon capture and storage (CCS) activities. The technology developed by way of this research project is referred to as microbially induced calcite precipitation (MICP).

Historical perspectives: The role of the NASA Lewis Research Center in the national space nuclear power programs

NASA Technical Reports Server (NTRS)

Bloomfield, H. S.; Sovie, R. J.

1991-01-01

The history of the NASA Lewis Research Center's role in space nuclear power programs is reviewed. Lewis has provided leadership in research, development, and the advancement of space power and propulsion systems. Lewis' pioneering efforts in nuclear reactor technology, shielding, high temperature materials, fluid dynamics, heat transfer, mechanical and direct energy conversion, high-energy propellants, electric propulsion and high performance rocket fuels and nozzles have led to significant technical and management roles in many national space nuclear power and propulsion programs.

The CSM testbed software system: A development environment for structural analysis methods on the NAS CRAY-2

NASA Technical Reports Server (NTRS)

Gillian, Ronnie E.; Lotts, Christine G.

1988-01-01

The Computational Structural Mechanics (CSM) Activity at Langley Research Center is developing methods for structural analysis on modern computers. To facilitate that research effort, an applications development environment has been constructed to insulate the researcher from the many computer operating systems of a widely distributed computer network. The CSM Testbed development system was ported to the Numerical Aerodynamic Simulator (NAS) Cray-2, at the Ames Research Center, to provide a high end computational capability. This paper describes the implementation experiences, the resulting capability, and the future directions for the Testbed on supercomputers.

The Amphibian Research and Monitoring Initiative (ARMI): 5-year report

USGS Publications Warehouse

Muths, Erin; Gallant, Alisa L.; Campbell Grant, Evan H.; Battaglin, William A.; Green, David E.; Staiger, Jennifer S.; Walls, Susan C.; Gunzburger, Margaret S.; Kearney, Rick F.

2006-01-01

This report is a 5-year retrospective of the structure, methodology, progress, and contributions to the broader scientific community that have resulted from this national USGS program. We evaluate ARMI’s success to date, with regard to the challenges faced by the program and the strengths that have emerged. We chart objectives for the next 5 years that build on current accomplishments, highlight areas meriting further research, and direct efforts to overcome existing weaknesses.

Expanding the Scope of Site-Specific Recombinases for Genetic and Metabolic Engineering

PubMed Central

Gaj, Thomas; Sirk, Shannon J.; Barbas, Carlos F.

2014-01-01

Site-specific recombinases are tremendously valuable tools for basic research and genetic engineering. By promoting high-fidelity DNA modifications, site-specific recombination systems have empowered researchers with unprecedented control over diverse biological functions, enabling countless insights into cellular structure and function. The rigid target specificities of many sites-specific recombinases, however, have limited their adoption in fields that require highly flexible recognition abilities. As a result, intense effort has been directed toward altering the properties of site-specific recombination systems by protein engineering. Here, we review key developments in the rational design and directed molecular evolution of site-specific recombinases, highlighting the numerous applications of these enzymes across diverse fields of study. PMID:23982993

Impact of remote sensing upon the planning, management, and development of water resources

NASA Technical Reports Server (NTRS)

Loats, H. L.; Fowler, T. R.; Frech, S. L.

1974-01-01

A survey of the principal water resource users was conducted to determine the impact of new remote data streams on hydrologic computer models. The analysis of the responses and direct contact demonstrated that: (1) the majority of water resource effort of the type suitable to remote sensing inputs is conducted by major federal water resources agencies or through federally stimulated research, (2) the federal government develops most of the hydrologic models used in this effort; and (3) federal computer power is extensive. The computers, computer power, and hydrologic models in current use were determined.

LES, DNS and RANS for the analysis of high-speed turbulent reacting flows

NASA Technical Reports Server (NTRS)

Adumitroaie, V.; Colucci, P. J.; Taulbee, D. B.; Givi, P.

1995-01-01

The purpose of this research is to continue our efforts in advancing the state of knowledge in large eddy simulation (LES), direct numerical simulation (DNS), and Reynolds averaged Navier Stokes (RANS) methods for the computational analysis of high-speed reacting turbulent flows. In the second phase of this work, covering the period 1 Aug. 1994 - 31 Jul. 1995, we have focused our efforts on two programs: (1) developments of explicit algebraic moment closures for statistical descriptions of compressible reacting flows and (2) development of Monte Carlo numerical methods for LES of chemically reacting flows.

Institutional Infrastructure for Broader Impacts Engagement - Showcasing Effective Strategies and Approaches from a Large Research Institute

NASA Astrophysics Data System (ADS)

Gold, A. U.; Sullivan, S. B.; Smith, L. K.; Lynds, S. E.

2014-12-01

The need for robust scientific and especially climate literacy is increasing. Funding agencies mandate that scientists make their findings and data publically available. Ideally, this mandate is achieved by scientists and educators working together to translate research findings into common knowledge. The Cooperative Institute for Research in Environmental Sciences (CIRES) is the largest research institute at the University of Colorado and home institute to over 500 scientists. CIRES provides an effective organizational infrastructure to support its scientists in broadening their research impact. Education specialists provide the necessary experience, connections, logistical support, and evaluation expertise to develop and conduct impactful education and outreach efforts. Outreach efforts are tailored to the project needs and the scientists' interests. They span from deep engagement efforts with a high time commitment by the scientist thus a high dosage to short presentations by the scientists that reach many people without stimulating a deep engagement and have therefore a low dosage. We use three examples of current successful programs to showcase these different engagement levels and report on their impact: i) deep transformative and time-intensive engagement through a Research Experience for Community College students program, ii) direct engagement during a teacher professional development workshop centered around a newly developed curriculum bringing authentic climate data into secondary classrooms, iii) short-time engagement through a virtual panel discussion about the state of recent climate science topics, the recordings of which were repurposed in a Massive Open Online Course (MOOC). In this presentation, we discuss the challenges and opportunities of broader impacts work. We discuss successful strategies that we developed, stress the importance of robust impact evaluation, and summarize different avenues of funding outreach efforts.

Multidisciplinary Design Technology Development: A Comparative Investigation of Integrated Aerospace Vehicle Design Tools

NASA Technical Reports Server (NTRS)

Renaud, John E.; Batill, Stephen M.; Brockman, Jay B.

1998-01-01

This research effort is a joint program between the Departments of Aerospace and Mechanical Engineering and the Computer Science and Engineering Department at the University of Notre Dame. Three Principal Investigators; Drs. Renaud, Brockman and Batill directed this effort. During the four and a half year grant period, six Aerospace and Mechanical Engineering Ph.D. students and one Masters student received full or partial support, while four Computer Science and Engineering Ph.D. students and one Masters student were supported. During each of the summers up to four undergraduate students were involved in related research activities. The purpose of the project was to develop a framework and systematic methodology to facilitate the application of Multidisciplinary Design Optimization (N4DO) to a diverse class of system design problems. For all practical aerospace systems, the design of a systems is a complex sequence of events which integrates the activities of a variety of discipline "experts" and their associated "tools". The development, archiving and exchange of information between these individual experts is central to the design task and it is this information which provides the basis for these experts to make coordinated design decisions (i.e., compromises and trade-offs) - resulting in the final product design. Grant efforts focused on developing and evaluating frameworks for effective design coordination within a MDO environment. Central to these research efforts was the concept that the individual discipline "expert", using the most appropriate "tools" available and the most complete description of the system should be empowered to have the greatest impact on the design decisions and final design. This means that the overall process must be highly interactive and efficiently conducted if the resulting design is to be developed in a manner consistent with cost and time requirements. The methods developed as part of this research effort include; extensions to a sensitivity based Concurrent Subspace Optimization (CSSO) MDO algorithm; the development of a neural network response surface based CSSO-MDO algorithm; and the integration of distributed computing and process scheduling into the MDO environment. This report overviews research efforts in each of these focus. A complete bibliography of research produced with support of this grant is attached.

Development Status of Amine-based, Combined Humidity, CO2, and Trace Contaminant Control System for CEV

NASA Technical Reports Server (NTRS)

Smith, Fred; Perry, Jay; Nalette, Tim; Papale, William

2006-01-01

Under a NASA-sponsored technology development project, a multi-disciplinary team consisting of industry, academia, and government organizations lead by Hamilton Sundstrand is developing an amine-based humidity and CO2 removal process and prototype equipment for Vision for Space Exploration (VSE) applications. Originally this project sought to research enhanced amine formulations and incorporate a trace contaminant control capability into the sorbent. In October 2005, NASA re-directed the project team to accelerate the delivery of hardware by approximately one year and emphasize deployment on board the Crew Exploration Vehicle (CEV) as the near-term developmental goal. Preliminary performance requirements were defined based on nominal and off-nominal conditions and the design effort was initiated using the baseline amine sorbent, SA9T. As part of the original project effort, basic sorbent development was continued with the University of Connecticut and dynamic equilibrium trace contaminant adsorption characteristics were evaluated by NASA. This paper summarizes the University sorbent research effort, the basic trace contaminant loading characteristics of the SA9T sorbent, design support testing, and the status of the full-scale system hardware design and manufacturing effort.

Entering a New ERA: Education Resources and AGU

NASA Astrophysics Data System (ADS)

Karsten, J. L.; Johnson, R. M.

2001-12-01

Professional societies play a unique role in the on-going battle to improve public education in the Earth and space sciences. With guidance from its Committee on Education and Human Resources (CEHR), AGU has traditionally sponsored strong programs that provide mechanisms for linking its research membership with the formal/informal science education communities. Among the most successful of these are tutorials for K-12 teachers taught by AGU members during national meetings (e.g., GIFT - Geophysical Information For Teachers) and internships that allow teachers to experience geophysical science research first-hand (e.g., STaRS - Science Teacher and Research Scientist). AGU also co-sponsors major symposia to discuss and develop strategies for Earth science education reform (e.g., the NSF-sponsored Shaping the Future workshop) and provides an annual forum for the Heads and Chairs of undergraduate geoscience departments to discuss common problems and share solutions. In the fall of 2001, AGU expects to unveil a major new education and outreach website that will provide enhanced opportunities for communicating to students, teachers and the public about AGU members' research and new directions in geophysical science education. The most important contribution that AGU makes, however, is to validate and prominently endorse the education and outreach efforts of its members, both by sponsoring well-attended, education-related special sessions at AGU national meetings and by annually honoring individuals or groups with the Excellence in Geoscience Education award. Recent staff changes at AGU headquarters have brought new opportunities to expand upon these successful existing programs and move in other directions that capitalize on the strengths of the organization. Among new initiatives being considered are programs that partner education efforts with those being developed as part of several large research programs, curriculum modules that will promote teaching earth sciences-related materials within core physics, chemistry, and math curricula, and more sophisticated informal science education programs. Efforts to better coordinate AGU's education programs with those being developed by other professional geoscience organizations are also underway.

The History, Status, Gaps, and Future Directions of Neurotoxicology in China

PubMed Central

Cai, Tongjian; Luo, Wenjing; Ruan, Diyun; Wu, Yi-Jun; Fox, Donald A.; Chen, Jingyuan

2016-01-01

Background: Rapid economic development in China has produced serious ecological, environmental, and health problems. Neurotoxicity has been recognized as a major public health problem. The Chinese government, research institutes, and scientists conducted extensive studies concerning the source, characteristics, and mechanisms of neurotoxicants. Objectives: This paper presents, for the first time, a comprehensive history and review of major sources of neurotoxicants, national bodies/legislation engaged, and major neurotoxicology research in China. Methods: Peer-reviewed research and pollution studies by Chinese scientists from 1991 to 2015 were examined. PubMed, Web of Science and Chinese National Knowledge Infrastructure (CNKI) were the major search tools. Results: The central problem is an increased exposure to neurotoxicants from air and water, food contamination, e-waste recycling, and manufacturing of household products. China formulated an institutional framework and standards system for management of major neurotoxicants. Basic and applied research was initiated, and international cooperation was achieved. The annual number of peer-reviewed neurotoxicology papers from Chinese authors increased almost 30-fold since 2001. Conclusions: Despite extensive efforts, neurotoxicity remains a significant public health problem. This provides great challenges and opportunities. We identified 10 significant areas that require major educational, environmental, governmental, and research efforts, as well as attention to public awareness. For example, there is a need to increase efforts to utilize new in vivo and in vitro models, determine the potential neurotoxicity and mechanisms involved in newly emerging pollutants, and examine the effects and mechanisms of mixtures. In the future, we anticipate working with scientists worldwide to accomplish these goals and eliminate, prevent and treat neurotoxicity. Citation: Cai T, Luo W, Ruan D, Wu YJ, Fox DA, Chen J. 2016. The history, status, gaps, and future directions of neurotoxicology in China. Environ Health Perspect 124:722–732; http://dx.doi.org/10.1289/ehp.1409566 PMID:26824332

NASA research in aircraft propulsion

NASA Technical Reports Server (NTRS)

Beheim, M. A.

1982-01-01

A broad overview of the scope of research presently being supported by NASA in aircraft propulsion is presented with emphasis on Lewis Research Center activities related to civil air transports, CTOL and V/STOL systems. Aircraft systems work is performed to identify the requirements for the propulsion system that enhance the mission capabilities of the aircraft. This important source of innovation and creativity drives the direction of propulsion research. In a companion effort, component research of a generic nature is performed to provide a better basis for design and provides an evolutionary process for technological growth that increases the capabilities of all types of aircraft. Both are important.

Dopamine, Effort-Based Choice, and Behavioral Economics: Basic and Translational Research

PubMed Central

Salamone, John D.; Correa, Merce; Yang, Jen-Hau; Rotolo, Renee; Presby, Rose

2018-01-01

Operant behavior is not only regulated by factors related to the quality or quantity of reinforcement, but also by the work requirements inherent in performing instrumental actions. Moreover, organisms often make effort-related decisions involving economic choices such as cost/benefit analyses. Effort-based decision making is studied using behavioral procedures that offer choices between high-effort options leading to relatively preferred reinforcers vs. low effort/low reward choices. Several neural systems, including the mesolimbic dopamine (DA) system and other brain circuits, are involved in regulating effort-related aspects of motivation. Considerable evidence indicates that mesolimbic DA transmission exerts a bi-directional control over exertion of effort on instrumental behavior tasks. Interference with DA transmission produces a low-effort bias in animals tested on effort-based choice tasks, while increasing DA transmission with drugs such as DA transport blockers tends to enhance selection of high-effort options. The results from these pharmacology studies are corroborated by the findings from recent articles using optogenetic, chemogenetic and physiological techniques. In addition to providing important information about the neural regulation of motivated behavior, effort-based choice tasks are useful for developing animal models of some of the motivational symptoms that are seen in people with various psychiatric and neurological disorders (e.g., depression, schizophrenia, Parkinson’s disease). Studies of effort-based decision making may ultimately contribute to the development of novel drug treatments for motivational dysfunction. PMID:29628879

Dopamine, Effort-Based Choice, and Behavioral Economics: Basic and Translational Research.

PubMed

Salamone, John D; Correa, Merce; Yang, Jen-Hau; Rotolo, Renee; Presby, Rose

2018-01-01

Operant behavior is not only regulated by factors related to the quality or quantity of reinforcement, but also by the work requirements inherent in performing instrumental actions. Moreover, organisms often make effort-related decisions involving economic choices such as cost/benefit analyses. Effort-based decision making is studied using behavioral procedures that offer choices between high-effort options leading to relatively preferred reinforcers vs. low effort/low reward choices. Several neural systems, including the mesolimbic dopamine (DA) system and other brain circuits, are involved in regulating effort-related aspects of motivation. Considerable evidence indicates that mesolimbic DA transmission exerts a bi-directional control over exertion of effort on instrumental behavior tasks. Interference with DA transmission produces a low-effort bias in animals tested on effort-based choice tasks, while increasing DA transmission with drugs such as DA transport blockers tends to enhance selection of high-effort options. The results from these pharmacology studies are corroborated by the findings from recent articles using optogenetic, chemogenetic and physiological techniques. In addition to providing important information about the neural regulation of motivated behavior, effort-based choice tasks are useful for developing animal models of some of the motivational symptoms that are seen in people with various psychiatric and neurological disorders (e.g., depression, schizophrenia, Parkinson's disease). Studies of effort-based decision making may ultimately contribute to the development of novel drug treatments for motivational dysfunction.

Animals and the 3Rs in toxicology research and testing: The way forward.

PubMed

Stokes, W S

2015-12-01

Despite efforts to eliminate the use of animals in testing and the availability of many accepted alternative methods, animals are still widely used for toxicological research and testing. While research using in vitro and computational models has dramatically increased in recent years, such efforts have not yet measurably impacted animal use for regulatory testing and are not likely to do so for many years or even decades. Until regulatory authorities have accepted test methods that can totally replace animals and these are fully implemented, large numbers of animals will continue to be used and many will continue to experience significant pain and distress. In order to positively impact the welfare of these animals, accepted alternatives must be implemented, and efforts must be directed at eliminating pain and distress and reducing animal numbers. Animal pain and distress can be reduced by earlier predictive humane endpoints, pain-relieving medications, and supportive clinical care, while sequential testing and routine use of integrated testing and decision strategies can reduce animal numbers. Applying advances in science and technology to the development of scientifically sound alternative testing models and strategies can improve animal welfare and further reduce and replace animal use. © The Author(s) 2015.

A Systematic Review of Perennial Staple Crops Literature Using Topic Modeling and Bibliometric Analysis

PubMed Central

2016-01-01

Research on perennial staple crops has increased in the past ten years due to their potential to improve ecosystem services in agricultural systems. However, multiple past breeding efforts as well as research on traditional ratoon systems mean there is already a broad body of literature on perennial crops. In this review, we compare the development of research on perennial staple crops, including wheat, rice, rye, sorghum, and pigeon pea. We utilized the advanced search capabilities of Web of Science, Scopus, ScienceDirect, and Agricola to gather a library of 914 articles published from 1930 to the present. We analyzed the metadata in the entire library and in collections of literature on each crop to understand trends in research and publishing. In addition, we applied topic modeling to the article abstracts, a type of text analysis that identifies frequently co-occurring terms and latent topics. We found: 1.) Research on perennials is increasing overall, but individual crops have each seen periods of heightened interest and research activity; 2.) Specialist journals play an important role in supporting early research efforts. Research often begins within communities of specialists or breeders for the individual crop before transitioning to a more general scientific audience; 3.) Existing perennial agricultural systems and their domesticated crop material, such as ratoon rice systems, can provide a useful foundation for breeding efforts, accelerating the development of truly perennial crops and farming systems; 4.) Primary research is lacking for crops that are produced on a smaller scale globally, such as pigeon pea and sorghum, and on the ecosystem service benefits of perennial agricultural systems. PMID:27213283

Impact of Attention Biases to Threat and Effortful Control on Individual Variations in Negative Affect and Social Withdrawal in Very Young Children

PubMed Central

Zapp, Daniel J.; Fettig, Nicole B.; Pérez-Edgar, Koraly

2015-01-01

Early temperamental sensitivity may form the basis for the later development of socioemotional maladjustment. In particular, temperamental negative affect places children at risk for the development of anxiety. However, not all children who show negative affect go on to develop anxiety or extreme social withdrawal. Recent research indicates that reactive control, in the form of attention to threat, may serve as a bridge between early temperament and the development of later social difficulties. In addition, variation in effortful control may also modulate this trajectory. Children (MeanAge=5.57 years) were assessed for attention bias to threatening and pleasant faces using a dot-probe paradigm. Attention bias to threatening (but not happy) faces moderated the direct positive relation between negative affect and social withdrawal. Children with threat biases showed a significant link between negative affect and social withdrawal, while children who avoided threat did not. In contrast, effortful control did not moderate the relation between negative affect and social withdrawal. Rather, there was a direct negative relation between effortful control and social withdrawal. The findings from this short report indicate that the relation amongst temperament, attention bias, and social withdrawal appears early in life and point to early emerging specificity in reactive and regulatory functioning. PMID:26477597

Long-Term Trends in the Well-Being of Children and Youth: Issues in Children's and Families' Lives.

ERIC Educational Resources Information Center

Weissberg, Roger P., Ed.; Walberg, Herbert J., Ed.; O'Brien, Mary Utne, Ed.; Kuster, Carol Bartels, Ed.

Representing an important University of Colorado effort to relate university research directly to social policy and practice, this book examines several decades of indicators that reflect changes in children's behavior as well as social-environmental factors that influence their development. Articles in the book provide a volume overview and…

Factors Affecting Variance in Classroom Assessment Scoring System Scores: Season, Context, and Classroom Composition

ERIC Educational Resources Information Center

Buell, Martha; Han, Myae; Vukelich, Carol

2017-01-01

Early care and education programme quality is usually assessed at the classroom level. One such measure of classroom quality is the classroom assessment scoring system (CLASS). In an effort to ensure higher quality programming, the CLASS is being used to direct teacher professional development. However, there has been relatively little research on…

After twenty years of research on soil carbon and climate change, what's left to learn?

EPA Science Inventory

Much effort over the past 230 years has been directed at investigating the roles that soils and specifically soil carbon play in the global carbon cycle and in climate change. As we begin another new decade, we ask whether there is anything left to learn on this topic? Do we kn...

Adolescents' Psychological Well-Being and Perceived Parental Involvement: Implications for Parental Involvement in Middle Schools

ERIC Educational Resources Information Center

Cripps, Kayla; Zyromski, Brett

2009-01-01

Adolescence is a critical period of development. Previous research suggests parent involvement in school directly impacts student success. However, different types of parental involvement and the efforts of middle school personnel to educate parents about these effective practices have received scant attention in the literature. The level and type…

Stigma and Intellectual Disability: A Review of Related Measures and Future Directions

ERIC Educational Resources Information Center

Werner, Shirli; Corrigan, Patrick; Ditchman, Nicole; Sokol, Kristin

2012-01-01

The theoretical construct of stigma has received much attention in psychiatric disability research, leading to the development of widely used measures. Such measures have had real world impact in that they allow for the assessment of stigma change efforts. The study of stigma has not received the same level of attention for persons with…

A method for improved visual landscape compatibility of mobile home park

Treesearch

Daniel R. Jones

1979-01-01

This paper is a description of a research effort directed to improving the visual image of mobile home parks in the landscape. The study is an application of existing methodologies for measuring scenic quality and visual landscape compatibility to an unsolved problem. The paper summarizes two major areas of investigation: regional location factors based on visual...

The Best Laid Plans: Designing Incentive Programs for School Leaders. WCER Working Paper No. 2014-7

ERIC Educational Resources Information Center

Goff, Peter; Goldring, Ellen; Canney, Melissa

2014-01-01

Notable attention and effort has been directed toward improving educator productivity through the use of performance incentives. Little of this work has focused on incentive systems for school leaders (principals) and less yet examines performance pay systems used in practice. This research uses 34 funded grants from the federal Teacher Incentive…

Community Engagement, Globalisation, and Restorative Action: Approaching Systems and Research in the Universities

ERIC Educational Resources Information Center

Odora Hoppers, Catherine A.

2013-01-01

It is clear that there is a wide range of arguments that reflect varying degrees of disaffection with the university worldwide. A great deal of understandable effort is directed at the impact of globalisation, especially the way it is making universities engage in academic capitalism (Slaughter and Leslie, 1997). The alternative arguments…

Educational Choice--Thinking It Through. Insights on Educational Policy and Practice Number 8.

ERIC Educational Resources Information Center

Pollard, Joyce S.

Before charging blindly into the issues of implementing educational choice programs, states and local districts need to stop and think about direction for efforts to improve and restructure education. Recent research shows that the most successful choice systems are tailored to their community's needs. Among the plans that have been implemented…

Media and the Disadvantaged--A Review of the Literature.

ERIC Educational Resources Information Center

Wade, Serena E.

This review covers books, journal articles, and ERIC documents, 1966 and later. Much emphasis is placed on media program and project descriptions, rather than reports of completed research. The review points to trends of common media use and student performance and tries to shed some light on the general direction of future media efforts for the…

The Practice of Information Processing Model in the Teaching of Cognitive Strategies

ERIC Educational Resources Information Center

Ozel, Ali

2009-01-01

In this research, the differentiation condition of teaching the learning strategies depending on the time which the first grade of primary school teachers carried out to form an information-process skeleton on student is tried to be found out. This process including the efforts of 260 teachers in this direction consists of whether the adequate…

Constraints on the Multidisciplinary Approach: Uses and Misuses of the Kuhnian Paradigm.

ERIC Educational Resources Information Center

Parsons, Gerald Michael

The general enthusiasm that governs composition studies is the result of more than 20 years of collective efforts to define central issues in theory and research, and to help refocus national attention on composition literacy. The optimistic vision of future challenge and direction in discourse studies is largely premised on Thomas Kuhn's…

NASA/HAA Advanced Rotorcraft Technology and Tilt Rotor Workshops. Volume 1: Executive Summary

NASA Technical Reports Server (NTRS)

1980-01-01

This presentation provides an overview of the NASA Rotorcraft Program as an introduction to the technical sessions of the Advanced Rotorcraft Technology Workshop. It deals with the basis for NASA's increasing emphasis on rotorcraft technology, NASA's research capabilities, recent program planning efforts, highlights of its 10-year plan and future directions and opportunities.

Making Time for Instructional Leadership. Volume 1: The Evolution of the SAM Process

ERIC Educational Resources Information Center

Goldring, Ellen; Grissom, Jason A.; Neumerski, Christine M.; Murphy, Joseph; Blissett, Richard; Porter, Andy

2015-01-01

This three-volume report describes the "SAM (School Administration Manager) process," an approach that about 700 schools around the nation are using to direct more of principals' time and effort to improve teaching and learning in classrooms. Research has shown that a principal's instructional leadership is second only to teaching among…

Improving Agricultural Extension Services through University Outreach Initiatives: A Case of Farmers in Model Villages in Ogun State, Nigeria

ERIC Educational Resources Information Center

Oloruntoba, Abayomi; Adegbite, Dorcas A.

2006-01-01

University outreach is an educational and research-based information source enabling farmers to make decisions that improve the quality of their lives. This paper explores how collaborative efforts between the university and farmers have directly impacted in albeit Striga ("noxious witch weed") ravaged maize farms in rainforest farming…

A Study of Classroom Interaction and Thinking. Interim Report.

ERIC Educational Resources Information Center

Hudgins, Bryce B.; Ahlbrand, William P., Jr.

As a first step in a research effort directed toward formulation of a theory of instruction which would lead to prediction and control of classroom events, data related to teacher-pupil communication, student covert thinking, and teacher and pupil overt thinking was collected by two observers working over a 5-day period with each of nine junior…

Research, public policy and drug abuse: current approaches and new directions.

PubMed

Smith, J P

This article examines current U.S. research policy in the drug abuse field and comments on future directions. It discusses three main themes: (1) the relationship of national policy and research on drug abuse; (2) how research is planned and priorities are set at the National Institute on Drug Abuse; and (3) the need for a variety of policy studies on drug abuse to help develop more effective national prevention and control efforts. Examination of national policy statements on drug abuse supply and demand reduction issued by administrations from John F. Kennedy to Ronald W. Reagan suggests a lack of appreciation of the potential that research offers to aid public policy and an underutilization of research as a response to gaps in our knowledge of how to deal with drug problems. This paper proposes development of a National Research Strategy on Drug Abuse to identify research goals that reflect national policy needs. The importance and contribution of policy studies, as part of the National Research Strategy, are discussed with a plea for research to improve policy analysis and development.

Photocatalytic conversion of methane to methanol

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taylor, C.E.; Noceti, R.P.; D`Este, J.R.

1995-12-31

A long-term goal of our research group is the exploration of novel pathways for the direct oxidation of methane to liquid fuels, chemicals, and intermediates. The use of three relatively abundant and inexpensive reactants, light, water, and methane, to produce methanol is attractive. The products of reaction, methanol and hydrogen, are both commercially desirable, methanol being used as is or converted to a variety of other chemicals, and the hydrogen could be utilized in petroleum and/or chemical manufacturing. Methane is produced as a by-product of coal gasification. Depending upon reactor design and operating conditions, up to 18% of total gasifiermore » product may be methane. In addition, there are vast proven reserves of geologic methane in the world. Unfortunately, a large fraction of these reserves are in regions where there is little local demand for methane and it is not economically feasible to transport it to a market. There is a global research effort under way in academia, industry, and government to find methods to convert methane to useful, more readily transportable and storable materials. Methanol, the initial product of methane oxidation, is a desirable product of conversion because it retains much of the original energy of the methane while satisfying transportation and storage requirements. Investigation of direct conversion of methane to transportation fuels has been an ongoing effort at PETC for over 10 years. One of the current areas of research is the conversion of methane to methanol, under mild conditions, using light, water, and a semiconductor photocatalyst. The use of three relatively abundant and inexpensive reactants, light, water, and methane, to produce methanol, is attractive. Research in the laboratory is directed toward applying the techniques developed for the photocatalytic splitting of the water and the photochemical conversion of methane.« less

New linked data on research investments: scientific workforce, productivity, and public value

PubMed Central

Lane, Julia; Owen-Smith, Jason; Rosen, Rebecca; Weinberg, Bruce

2015-01-01

Longitudinal micro-data derived from transaction level information about wage and vendor payments made by federal grants on multiple U.S. campuses are being developed in a partnership involving researchers, university administrators, representatives of federal agencies, and others. This paper describes the UMETRICS data initiative that has been implemented under the auspices of the Committee on Institutional Cooperation. The resulting data set reflects an emerging conceptual framework for analyzing the process, products, and impact of research. It grows from and engages the work of a diverse and vibrant community. This paper situates the UMETRICS effort in the context of research evaluation and ongoing data infrastructure efforts in order to highlight its novel and valuable features. Refocusing data construction in this field around individuals, networks, and teams offers dramatic possibilities for data linkage, the evaluation of research investments, and the development of rigorous conceptual and empirical models. Two preliminary analyses of the scientific workforce and network approaches to characterizing scientific teams ground a discussion of future directions and a call for increased community engagement. PMID:26335785

The role of vision, speed, and attention in overcoming directional biases during arm movements.

PubMed

Dounskaia, Natalia; Goble, Jacob A

2011-03-01

Previous research has revealed directional biases (preferences to select movements in specific directions) during horizontal arm movements with the use of a free-stroke drawing task. The biases were interpreted as a result of a tendency to generate motion at either the shoulder or elbow (leading joint) and move the other (subordinate) joint predominantly passively to avoid neural effort for control of interaction torque. Here, we examined influence of vision, movement speed, and attention on the directional biases. Participants performed the free-stroke drawing task, producing center-out strokes in randomly selected directions. Movements were performed with and without vision and at comfortable and fast pace. A secondary, cognitive task was used to distract attention. Preferred directions remained the same in all conditions. Bias strength mildly increased without vision, especially during fast movements. Striking increases in bias strength were caused by the secondary task, pointing to additional cognitive load associated with selection of movements in the non-preferred directions. Further analyses demonstrated that the tendency to minimize active interference with interaction torque at the subordinate joint matched directional biases in all conditions. This match supports the explanation of directional biases as a result of a tendency to minimize neural effort for interaction torque control. The cognitive load may enhance this tendency in two ways, directly, by reducing neural capacity for interaction torque control, and indirectly, by decreasing capacity of working memory that stores visited directions. The obtained results suggest strong directional biases during daily activities because natural arm movements usually subserve cognitive tasks.

Aeropropulsion 1987. Session 4: Instrumentation and Controls Research

NASA Technical Reports Server (NTRS)

1987-01-01

The Lewis Research Center has had a long history of research directed toward advancing the national capability in the areas of propulsion research instrumentation and propulsion controls. Some of the major advances from this research that are currently in use are highlighted as well as some of the ongoing and planned research that will strongly impact the future capabilities. The presentations will cover the efforts on research instrumentation and controls as well as the research on high temperature electronics. This introductory section will focus on the major drivers or needs of the aeropropulsion industry that have shaped the instrumentation and controls research programs. Also covered will be the technological opportunities that have greatly impacted the program and that permitted break-throughs in several areas.

System safety engineering in the development of advanced surface transportation vehicles

NASA Technical Reports Server (NTRS)

Arnzen, H. E.

1971-01-01

Applications of system safety engineering to the development of advanced surface transportation vehicles are described. As a pertinent example, the paper describes a safety engineering efforts tailored to the particular design and test requirements of the Tracked Air Cushion Research Vehicle (TACRV). The test results obtained from this unique research vehicle provide significant design data directly applicable to the development of future tracked air cushion vehicles that will carry passengers in comfort and safety at speeds up to 300 miles per hour.

Theory underlying CRM training: Psychological issues in flight crew performance and crew coordination

NASA Technical Reports Server (NTRS)

Helmreich, Robert L.

1987-01-01

What psychological theory and research can reveal about training in Cockpit Resource Management (CRM) is summarized. A framework is provided for the critical analysis of current approaches to CRM training. Background factors and definitions critical to evaluating CRM are reviewed, followed by a discussion of issues directly related to CRM training effectiveness. Some of the things not known about the optimization of crew performance and the research needed to make these efforts as effective as possible are described.

Results of a Research Study to Identify Historical RDTE (Research, Development, Test and Evaluation) Obligations and Expenditures on Major Army Materiel and Non-Materiel Systems,

DTIC Science & Technology

1983-10-01

SYSTEMS OBJECTIVES. This study was conducted as part of a continuing effort to obtain actual (historical) life cycle costs of major Army systems from...Procurement, AMS Code for RDTE, etc.). System life cycle costs cut across appropriation lines. A common architecture should be prerequisite to... life cycle costs of major Army systems have not been successful, but attention recently has been directed toward the possibility that a significant

Accuracy of trace element determinations in alternate fuels

NASA Technical Reports Server (NTRS)

Greenbauer-Seng, L. A.

1980-01-01

A review of the techniques used at Lewis Research Center (LeRC) in trace metals analysis is presented, including the results of Atomic Absorption Spectrometry and DC Arc Emission Spectrometry of blank levels and recovery experiments for several metals. The design of an Interlaboratory Study conducted by LeRC is presented. Several factors were investigated, including: laboratory, analytical technique, fuel type, concentration, and ashing additive. Conclusions drawn from the statistical analysis will help direct research efforts toward those areas most responsible for the poor interlaboratory analytical results.

Research and development needs in the Department of Energy. Interim report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-09-05

In April 1980, the Deputy Secretary requested that the Board participate in the Department's review of the technology base component of DOE's R and D programs and that the Board address the following broad concerns: (1) The adequacy of the research underpinning for technology development programs; (2) Possible gaps or duplications of effort; (3) The balance among research performers (universities, laboratories, industry); (4) Significant R and D opportunities that DOE's programs may be missing. The Board offered the following recommendations to the Secretary: (1) Place greater research emphasis on environmental and health issues to ensure the success of the nationalmore » synfuels program. (2) Provide more research in energy use and productivity projects. (3) Increase the level of effort in basic research. (4) Place higher priority for high-level radioactive waste disposal R and D. (5) Evaluate the various energy technology options on a common comparison basis to clearly identify the costs, benefits and risks of each option. (6) Develop more effective DOE procurement practices. Additional recommendations were directed to the Under Secretary and Assistant Secretaries of Energy reviewing specific issues in conservation, fossil, nuclear and solar energy, resource applications, environment, and energy research.« less

What is known about tobacco industry efforts to influence tobacco tax? A systematic review of empirical studies.

PubMed

Smith, Katherine E; Savell, Emily; Gilmore, Anna B

2013-03-01

To systematically review studies of tobacco industry efforts to influence tobacco tax policies. Searches were conducted between 1 October 2009 and 31 March 2010 in 14 databases/websites, in relevant bibliographies and via experts. Studies were included if they focused on industry efforts to influence tobacco tax policies, drew on empirical evidence, were in English and concerned the period 1985-2010. In total, 36 studies met these criteria. Two reviewers undertook data extraction and critical appraisal. A random selection of 15 studies (42%) was subject to second review. Evidence was assessed thematically to identify distinct tobacco industry aims, arguments and tactics. A total of 34 studies examined industry efforts to influence tax levels. They suggest the tobacco industry works hard to prevent significant increases and particularly dislikes taxes 'earmarked' for tobacco control. Key arguments to counter increases are that tobacco taxes are socially regressive, unfair and lead to increased levels of illicit trade and negative economic impacts. For earmarked taxes, the industry also frequently tries to raise concerns about revenue allocation. Assessing industry arguments against established evidence demonstrates most are unsupported. Key industry tactics include: establishing 'front groups', securing credible allies, direct lobbying and publicity campaigns. Only seven studies examined efforts to influence tax structures. They suggest company preferences vary and tactics centre on direct lobbying. The tobacco industry has historically tried to keep tobacco taxes low using consistent tactics and misleading arguments. Further research is required to explore efforts to influence tax structures, excise policies beyond the USA and recent policies.

What is known about tobacco industry efforts to influence tobacco tax? A systematic review of empirical studies

PubMed Central

Smith, K.E.; Savell, E.; Gilmore, A.B.

2013-01-01

Objective To systematically review studies of tobacco industry efforts to influence tax policies. Data sources We conducted searches between 1st October 2009 and 31st March 2010 on 14 databases/websites, in relevant bibliographies and via experts. Study selection We included studies if they: focused on industry efforts to influence tobacco tax policies; drew on empirical evidence; were in English; concerned the period 1985–2010. 36 studies met these criteria. Data extraction Two reviewers undertook data extraction and critical appraisal. A random selection of 15 studies (42%) was subject to second review. Data synthesis We assessed evidence thematically to identify distinct tobacco industry aims, arguments and tactics. 34 studies examined industry efforts to influence tax levels. They suggest industry works hard to prevent significant increases and particularly dislikes taxes ‘earmarked’ for tobacco control. Key arguments to counter increases are that tobacco taxes are socially regressive, unfair and lead to increased levels of illicit trade and negative economic impacts. For earmarked taxes, the industry also frequently tries to raise concerns about revenue allocation. Assessing industry arguments against established evidence demonstrates most are unsupported. Key industry tactics include: establishing ‘front groups’; securing credible allies, direct lobbying; and publicity campaigns. Only seven studies examined efforts to influence tax structures. They suggest company preferences vary and tactics centre on direct lobbying. Conclusions The tobacco industry has historically tried to keep tobacco taxes low using consistent tactics and misleading arguments. Further research is required to explore efforts to influence: tax structures; excise policies beyond the US; recent policies. PMID:22887175

Biological Effects of Directed Energy

NASA Astrophysics Data System (ADS)

Dayton, Thomas; Beason, Charles; Hitt, M. K.; Rogers, Walter; Cook, Michael

2002-11-01

This Final Report summarizes the biological effects research conducted by Veridian Engineering personnel under contract F41624-96-C-9009 in support of the Air Force Research Laboratory's Radio Frequency Radiation Branch from April 1997 to April 2002. Biological effects research and consultation were provided in five major areas: Active Denial System (also known as Vehicle Mounted Active Denial System), radio frequency radiation (RFR) health and safety, non-lethal weapon biological effects research, the newly formed Joint Non-Lethal Weapons Human Effects Center of Excellence, and Biotechnology. The report is organized by research efforts within the major research areas, providing title, objective, a brief description, relevance to the AF or DoD, funding, and products.

NASA thrusts in high-speed aeropropulsion research and development: An overview

NASA Technical Reports Server (NTRS)

Ziemianski, Joseph A.

1990-01-01

NASA is conducting aeronautical research over a broad range of Mach numbers. In addition to the advanced conventional takeoff or landing (CTOL) propulsion research described elsewhere, NASA Lewis has intensified its efforts towards propulsion technology for selected high speed flight applications. In a companion program, NASA Langley has also accomplished significant research in supersonic combustion ramjet (SCRAM) propulsion. An unclassified review is presented of the propulsion research results that are applicable for supersonic to hypersonic vehicles. This overview not only provides a preview of the more detailed presentations which follow, it also presents a viewpoint on future research directions by calling attention to the unique cycles, components, and facilities involved in this expanding area of work.

The Past Achievements and Future Promises of Developmental Psychopathology: The Coming of Age of a Discipline

PubMed Central

Cicchetti, Dante; Toth, Sheree L.

2012-01-01

Over the past decades, developmental psychopathology has coalesced into a discipline that has made significant contributions toward the understanding of risk, psychopathology, and resilience in individuals across the life course. The overarching goal of the discipline has been to elucidate the interplay among biological, psychological, and social-contextual aspects of normal and abnormal development. In addition to directing efforts toward bridging fields of study and aiding in elucidating important truths about the processes underlying adaptation and maladaptation, investigators in developmental psychopathology have been equally devoted to developing and evaluating methods for preventing and ameliorating maladaptive and psychopathological outcomes. Increasingly, efforts are being made to conduct investigations at multiple levels of analysis and to translate basic research knowledge into real world contexts. In this article, the contributions, challenges, and future directions of the field are highlighted. PMID:19175810

Monitoring osseointegration and developing intelligent systems (Conference Presentation)

NASA Astrophysics Data System (ADS)

Salvino, Liming W.

2017-05-01

Effective monitoring of structural and biological systems is an extremely important research area that enables technology development for future intelligent devices, platforms, and systems. This presentation provides an overview of research efforts funded by the Office of Naval Research (ONR) to establish structural health monitoring (SHM) methodologies in the human domain. Basic science efforts are needed to utilize SHM sensing, data analysis, modeling, and algorithms to obtain the relevant physiological and biological information for human-specific health and performance conditions. This overview of current research efforts is based on the Monitoring Osseointegrated Prosthesis (MOIP) program. MOIP develops implantable and intelligent prosthetics that are directly anchored to the bone of residual limbs. Through real-time monitoring, sensing, and responding to osseointegration of bones and implants as well as interface conditions and environment, our research program aims to obtain individualized actionable information for implant failure identification, load estimation, infection mitigation and treatment, as well as healing assessment. Looking ahead to achieve ultimate goals of SHM, we seek to expand our research areas to cover monitoring human, biological and engineered systems, as well as human-machine interfaces. Examples of such include 1) brainwave monitoring and neurological control, 2) detecting and evaluating brain injuries, 3) monitoring and maximizing human-technological object teaming, and 4) closed-loop setups in which actions can be triggered automatically based on sensors, actuators, and data signatures. Finally, some ongoing and future collaborations across different disciplines for the development of knowledge automation and intelligent systems will be discussed.

Aeroelasticity of wing and wing-body configurations on parallel computers

NASA Technical Reports Server (NTRS)

Byun, Chansup

1995-01-01

The objective of this research is to develop computationally efficient methods for solving aeroelasticity problems on parallel computers. Both uncoupled and coupled methods are studied in this research. For the uncoupled approach, the conventional U-g method is used to determine the flutter boundary. The generalized aerodynamic forces required are obtained by the pulse transfer-function analysis method. For the coupled approach, the fluid-structure interaction is obtained by directly coupling finite difference Euler/Navier-Stokes equations for fluids and finite element dynamics equations for structures. This capability will significantly impact many aerospace projects of national importance such as Advanced Subsonic Civil Transport (ASCT), where the structural stability margin becomes very critical at the transonic region. This research effort will have direct impact on the High Performance Computing and Communication (HPCC) Program of NASA in the area of parallel computing.

SF6-alternative gases for application in gas-insulated switchgear

NASA Astrophysics Data System (ADS)

Li, Xingwen; Zhao, Hu; Murphy, Anthony B.

2018-04-01

The environmental problems caused by greenhouse gases have received unprecedented attention. Sulfur hexafluoride (SF6), which is the preferred gas for use in gas-insulated switchgear (circuit breakers, disconnect switches, etc. for high-voltage electrical circuits), has a very high global warming potential, and there is a large international effort to find alternative gases. Recently, this effort has made important progress, with promising alternative gases being identified and tested. An overview, in particular the current state of the art, of the study of SF6-alternative gases is presented in the paper. The review focuses on the application of the SF6-alternative gases in gas-insulated switchgear, with detailed analysis of calculations and measurements of their basic physical properties, dielectric strengths, and arc-quenching capabilities. Finally, a discussion of and perspectives on current research and future research directions are presented.

Emotional Intelligence and Transformational Leadership in Nurse Managers.

PubMed

Spano-Szekely, Lauraine; Quinn Griffin, Mary T; Clavelle, Joanne; Fitzpatrick, Joyce J

2016-02-01

This study describes the relationship between emotional intelligence (EI) and transformational leadership (TL) in nurse managers (NMs). Effective NM leadership is important as they have direct influence over RN performance and patient outcomes. Research has demonstrated that a TL style generates greater commitment from followers than other leadership styles. EI is 1 potential characteristic of TL. A descriptive exploratory research study was conducted to correlate EI and TL practices of NMs. EI was significantly positively correlated with TL and outcome measures of extra-effort, effectiveness, and satisfaction and significantly negatively correlated with laissez-faire leadership. A positive relationship was found between TL and NMs with advanced education and administrative certification. Nursing administrators should consider EI characteristics when hiring NMs and lead efforts to advance education to align with organization needs for business and strategic essentials necessary for NM effectiveness.

Efforts to develop a cultured sponge cell line: revisiting an intractable problem.

PubMed

Grasela, James J; Pomponi, Shirley A; Rinkevich, Buki; Grima, Jennifer

2012-01-01

Residents of the marine environment, sponges (Porifera) have the ability to produce organic compounds known as secondary metabolites, which are not directly involved in the normal growth, development, or reproduction of an organism. Because of their sessile nature, the production of these bioactive compounds has been interpreted as a functional adaptation to serve in an important survival role as a means to counter various environmental stress factors such as predation, overgrowth by fouling organisms, or competition for limited space. Regardless of the reasons for this adaptation, a variety of isolated compounds have already proven to demonstrate remarkable anticancer, fungicidal, and antibiotic properties. A major obstacle to the isolation and production of novel compounds from sponges is the lack of a large, reliable source of sponge material. Sponge collection from the sea would be environmentally detrimental to the already stressed and sparse sponge populations. Sponge production in an aquaculture setting might appear to be an ideal alternative but would also be cost-ineffective and sponge growth is extremely slow. A third approach involves the development of a sponge cell culture system capable of producing the necessary cell numbers to harvest for research purposes as well as for the eventual commercial-scale production of promising bioactive compounds. Unfortunately, little progress has been made in this direction other than the establishment of temporary cultures containing aggregates and fragments of cells. One impediment toward successful sponge cell culture might be ascribed to a lack of published knowledge of failed methodologies, and thus, time and effort is wasted on continued reinvention of the same methods and procedures. Consequently, we have undertaken here to chart some of our unsuccessful research efforts, our methodology, and results to provide the sponge research community with knowledge to assist them to better avoid taking the same failed pathways.

NASA Education Recommendation Report - Education Design Team 2011

NASA Technical Reports Server (NTRS)

Pengra, Trish; Stofan, James

2011-01-01

NASA people are passionate about their work. NASA's missions are exciting to learners of all ages. And since its creation in 1958, NASA's people have been passionate about sharing their inspiring discoveries, research and exploration with students and educators. In May 2010, NASA administration chartered an Education Design Team composed of 12 members chosen from the Office of Education, NASA's Mission Directorates and Centers for their depth of knowledge and education expertise, and directed them to evaluate the Agency's program in the context of current trends in education. By improving NASA's educational offerings, he was confident that the Agency can play a leading role in inspiring student interest in science, technology, engineering and mathematics (STEM) as few other organizations can. Through its unique workforce, facilities, research and innovations, NASA can expand its efforts to engage underserved and underrepresented communities in science and mathematics. Through the Agency's STEM education efforts and science and exploration missions, NASA can help the United States successfully compete, prosper and be secure in the 21st century global community. After several months of intense effort, including meeting with education experts; reviewing Administration policies, congressional direction and education research; and seeking input from those passionate about education at NASA, the Education Design Team made six recommendations to improve the impact of NASA's Education Program: (1) Focus the NASA Education Program to improve its impact on areas of greatest national need (2) Identify and strategically manage NASA Education partnerships (3) Participate in National and State STEM Education policy discussions (4) Establish a structure to allow the Office of Education, Centers and Mission Directorates to implement a strategically integrated portfolio (5) Expand the charter of the Education Coordinating Committee to enable deliberate Education Program design (6) Improve communication to inspire learners

Load emphasizes muscle effort minimization during selection of arm movement direction

PubMed Central

2012-01-01

Background Directional preferences during center-out horizontal shoulder-elbow movements were previously established for both the dominant and non-dominant arm with the use of a free-stroke drawing task that required random selection of movement directions. While the preferred directions were mirror-symmetrical in both arms, they were attributed to a tendency specific for the dominant arm to simplify control of interaction torque by actively accelerating one joint and producing largely passive motion at the other joint. No conclusive evidence has been obtained in support of muscle effort minimization as a contributing factor to the directional preferences. Here, we tested whether distal load changes directional preferences, making the influence of muscle effort minimization on the selection of movement direction more apparent. Methods The free-stroke drawing task was performed by the dominant and non-dominant arm with no load and with 0.454 kg load at the wrist. Motion of each arm was limited to rotation of the shoulder and elbow in the horizontal plane. Directional histograms of strokes produced by the fingertip were calculated to assess directional preferences in each arm and load condition. Possible causes for directional preferences were further investigated by studying optimization across directions of a number of cost functions. Results Preferences in both arms to move in the diagonal directions were revealed. The previously suggested tendency to actively accelerate one joint and produce passive motion at the other joint was supported in both arms and load conditions. However, the load increased the tendency to produce strokes in the transverse diagonal directions (perpendicular to the forearm orientation) in both arms. Increases in required muscle effort caused by the load suggested that the higher frequency of movements in the transverse directions represented increased influence of muscle effort minimization on the selection of movement direction. This interpretation was supported by cost function optimization results. Conclusions While without load, the contribution of muscle effort minimization was minor, and therefore, not apparent, the load revealed this contribution by enhancing it. Unlike control of interaction torque, the revealed tendency to minimize muscle effort was independent of arm dominance. PMID:23035925

The Learning Assistant Model for Science Teacher Recruitment and Preparation

NASA Astrophysics Data System (ADS)

Otero, Valerie

2006-04-01

There is a shortage of high quality physical science teachers in the United States. In 2001, less than 50% of teachers who taught physics held a major or minor in physics or physics education (Neuschatz & McFarling, 2003). Studies point to content knowledge as one of the two factors that is positively correlated with teacher quality. However, those directly responsible for the science content preparation of teachers, specifically science research faculty, are rarely involved in focused efforts to improve teacher quality or to create alternative paths for becoming a teacher. What role should science research faculty play in the recruitment and preparation of science teachers? How might teacher recruitment and preparation be conceived so that science research faculty members' participation in these efforts is not at odds with the traditional scientific research foci of science research departments? To address this issue, we have coupled our teacher recruitment and preparation efforts with our efforts for transforming our large-enrollment, undergraduate science courses. This is achieved through the undergraduate Learning Assistant (LA) program, where talented mathematics and science majors are hired to assist in transforming large enrollment courses to student-centered, collaborative environments. These LAs are the target of our teacher recruitment efforts. Science research faculty, in collaboration with faculty from the school of education have established a community that supports LAs in making decisions to explore K12 teaching as a career option. Fifteen percent of the LAs who have participated in this program have entered teaching credential programs and now plan to become K12 teachers. An added effect of this program is that research faculty have developed skills and knowledge regarding inquiry-based and student-centered pedagogy and theories of student learning. The Learning Assistant program has led to increased subject matter knowledge among learning assistants, increased interest in K-12 teaching as a career, and increased appreciation and understanding of student-centered and inquiry-based learning. Data to support these claims will be presented. Neuschatz, M. & McFarling, M. (2003). Broadning the Base: High School Physics Education at the Turn of a New Century, AIP Report No. R-439.

Transparent stakeholder engagement in practice: Lessons learned from applying comprehensive environmental assessment to research planning for nanomaterials.

PubMed

Powers, Christina; Hendren, Christine; Wang, Amy; Davis, J Michael

2014-10-01

As efforts to develop new applications of engineered nanoscale materials (ENMs) continue to grow, so too has interest in the environmental, health, and safety (EHS) implications of these materials. However, thorough evaluation and interpretation of such implications could require substantial resources (e.g., estimated as >$120 million per year in federal funding 2013-2017). A structured, strategic approach for transparently planning research would support improved linkages between ENM research and risk assessments, and thereby enhance the utility of financial and other resources for EHS studies of ENMs. For this reason, we applied Comprehensive Environmental Assessment (CEA) as an approach to provide transparent input into research planning for 2 types of ENMs: nanoscale titanium dioxide and nanoscale silver. For each of these CEA applications, we employed a collective judgment method known as Nominal Group Technique (NGT) in 2 workshops sponsored by the US Environmental Protection Agency (USEPA). The objective of this paper is to present the outcomes of these CEA applications in the context of how our methodology can inform future efforts to identify collective goals in science (e.g., research priorities) through structured decision support approaches. Outcomes include clear lists of research priorities for each ENM developed through transparently engaging stakeholders having diverse technical and sector perspectives. In addition, we identified several procedural aspects that could be refined, including emphasizing breakout group interactions, identifying broad information priorities before more detailed research questions, and using rating rather than ranking prioritization methods. Beyond the research directions identified for specific ENMs, lessons learned about engaging stakeholders in research planning are expected to inform future research planning efforts for ENMs and other emerging materials across the scientific community. © 2014 SETAC.

SPINOFF 2000

NASA Technical Reports Server (NTRS)

2000-01-01

For the past 42 years, NASA has made special efforts to ensure the widest possible dissemination of its research and technology developments. We share the wealth of technology developed for our missions with the nation's industries to contribute to US economic strength and quality of life. For the past 27 years, this publication has provided you with over 1,200 examples of products and services developed as a direct result of commercial partnerships between NASA and the business community. Examples have covered products from fire retardant materials and air pollution monitors to non-invasive cardiac monitors and sensors for environmental control. In the Technology Transfer and Outreach section of Spinoff 2000, we highlight the activities of our Ames Research Center's Commercial Technology Office (CTO). Their efforts to facilitate and support technology commercialization are representative of the CTO at each field center. Increased activities to accelerate the dissemination of technologies, speed up the process of patent licensing, quicken the release of software for beta testing, support and manage incubators, and hasten the collaboration with commercial and academic organizations will continue to maximize the earliest potential commercial utilization of NASA's new inventions and technologies. Spinoff 2000 is organized into three sections: (1) Aerospace and Development highlights major research and development efforts currently carried out at the 10 NASA field centers; (2) Commercial Benefits-Spinoffs describes commercially available products and services resulting from the transfer of NASA technology; and (3) Technology Transfer and Outreach features this year's center spotlight, NASA's Ames Research Center, and its commercialization efforts, as well as the mechanisms in place nationwide to assist US industry in obtaining, transferring, and applying NASA technology, expertise, and assistance.

Commercial applications of new photovoltaic technologies

NASA Technical Reports Server (NTRS)

Mcconnell, R.

1991-01-01

The National Renewable Energy Laboratory (NREL) has directed and managed photovoltaic (PV) research and development (R&D) activities for the Department of Energy for more than 13 years. The NREL budget for these activities is almost $33 million for FY 1991. With the world's increasing concern for the environment and the United States' renewed apprehension over secure and adequate energy supplies, the use of semiconducting materials for the direct conversion of sunlight to electricity - photovoltaics - is an excellent example of government-supported high technology ready for further development by U.S. companies. Some new PV technologies and their research progress, some commercial applications of PV, and NREL's technology transfer activities for helping U.S. industry in its efforts to bring new products or services to the marketplace are described.

Expanding the scope of site-specific recombinases for genetic and metabolic engineering.

PubMed

Gaj, Thomas; Sirk, Shannon J; Barbas, Carlos F

2014-01-01

Site-specific recombinases are tremendously valuable tools for basic research and genetic engineering. By promoting high-fidelity DNA modifications, site-specific recombination systems have empowered researchers with unprecedented control over diverse biological functions, enabling countless insights into cellular structure and function. The rigid target specificities of many sites-specific recombinases, however, have limited their adoption in fields that require highly flexible recognition abilities. As a result, intense effort has been directed toward altering the properties of site-specific recombination systems by protein engineering. Here, we review key developments in the rational design and directed molecular evolution of site-specific recombinases, highlighting the numerous applications of these enzymes across diverse fields of study. © 2013 Wiley Periodicals, Inc.

U.S. Geological Survey research in radioactive waste disposal - Fiscal years 1986-1990

USGS Publications Warehouse

Trask, N.J.; Stevens, P.R.

1991-01-01

The report summarizes progress on geologic and hydrologic research related to the disposal of radioactive wastes. The research efforts are categorized according to whether they are related most directly to: (1) high-level wastes, (2) transuranic wastes, (3) low-level and mixed low-level and hazardous wastes, or (4) uranium mill tailings. Included is research applicable to the identification and geohydrologic characterization of waste-disposal sites, to investigations of specific sites where wastes have been stored, to development of techniques and methods for characterizing disposal sites, and to studies of geologic and hydrologic processes related to the transport and/or retention of waste radionuclides.

NEWSdm: Nuclear Emulsions for WIMP Search with directional measurement

NASA Astrophysics Data System (ADS)

Di Crescenzo, A.

2017-12-01

Direct Dark Matter searches are nowadays one of the most exciting research topics. Several experimental efforts are concentrated on the development, construction, and operation of detectors looking for the scattering of target nuclei with Weakly Interactive Massive Particles (WIMPs). The measurement of the direction of WIMP-induced nuclear recoils is a challenging strategy to extend dark matter searches beyond the neutrino floor and provide an unambiguous signature of the detection of Galactic dark matter. Current directional experiments are based on the use of gas TPC whose sensitivity is strongly limited by the small achievable detector mass. We present an innovative directional experiment based on the use of a solid target made by newly developed nuclear emulsions and read-out systems reaching a position resolution of the order of 10 nm.

The Political Future of Social Medicine: Reflections on Physicians as Activists.

PubMed

Geiger, H Jack

2017-03-01

The academic discipline of social medicine has always had a political and policy advocacy component, in addition to its core functions of research and teaching. Its origins lie in the 18th and 19th centuries, in the work of Johann Peter Frank and Rudolph Virchow, among others. Virchow's dictum that "politics is nothing else but medicine on a large scale" highlights that most social determinants of health are politically determined and shape population health. Yet despite intense epidemiological and sociological research on the social determinants of health, less attention has been paid to this political and policy dimension.During the 1960s, the author and many other clinicians were directly involved in attempts to use health care institutions to foster structural change. However, the author argues that efforts to assist individual patients and more effectively manage their interactions with the health care system, as described in the articles in this issue's special collection on "structural competency," while worthy and useful, do not confront root causes. Going forward, efforts to effect structural change must take place outside the arena of the clinical encounter and involve interprofessional teams and collaborations with nongovernmental organizations. They should intervene directly on the structures that contribute to illness such as poor housing, income and wealth inequality, inferior education, racism and residential segregation, and toxic concentrations of extreme poverty in urban areas. Collectively, these efforts-within and outside the spheres of medicine-represent the real operative form of structural competency.

Future directions in the use of dental implants.

PubMed

Bloem, T J

1989-10-01

Future development in implant prosthodontics should be based on the fundamentals of sound research and reliable clinical implementation. The goals should be to research the safety and efficacy of implants with regard to materials, host receptor site and interfacial zone; to develop acceptable uniform standards of evaluation; and to submit findings to scientific methods of analysis in determining benefit-to-risk factors. This presentation will offer a glimpse at some current developments in basic and clinical research focusing on studies in biocompatability and host acceptance; the implant-tissue interface; processes in osteogenesis related to vascularization of host sites; and bioengineering studies related to stress analysis and dimensional accuracy of impression systems for implants. The presentation will further describe future direction in research, training and implementation of services through development of an interdisciplinary team. A center is proposed to address the need for combined efforts in clinical and basic science research, the broad scope of implant utilization, and the teaching of implant procedures within an academic setting and to our colleagues.

Neurogenetics of Depression: A Focus on Reward Processing and Stress Sensitivity

PubMed Central

Bogdan, Ryan; Nikolova, Yuliya S.; Pizzagalli, Diego A.

2013-01-01

Major depressive disorder (MDD) is etiologically complex and has a heterogeneous presentation. This heterogeneity hinders the ability of molecular genetic research to reliably detect the small effects conferred by common genetic variation. As a result, significant research efforts have been directed at investigating more homogenous intermediate phenotypes believed to be more proximal to gene function and lie between genes and/or environmental effects and disease processes. In the current review we survey and integrate research on two promising intermediate phenotypes linked to depression: reward processing and stress sensitivity. A synthesis of this burgeoning literature indicates that a molecular genetic approach focused on intermediate phenotypes holds significant promise to fundamentally improve our understanding of the pathophysiology and etiology of depression, which will be required for improved diagnostic definitions and the development of novel and more efficacious treatment and prevention strategies. We conclude by highlighting challenges facing intermediate phenotype research and future development that will be required to propel this pivotal research into new directions. PMID:22659304

Enhancing Human Responses to Climate Change Risks through Simulated Flooding Experiences

NASA Astrophysics Data System (ADS)

Zaalberg, Ruud; Midden, Cees

Delta areas are threatened by global climate change. The general aims of our research were (1) to increase our understanding of climate and flood risk perceptions and the factors that influence these judgments, and (2) to seek for interventions that can contribute to a realistic assessment by laypersons of long-term flooding risks. We argue that awareness of one's own vulnerability to future flooding and insights into the effectiveness of coping strategies is driven by direct flooding experiences. In the current research multimodal sensory stimulation by means of interactive 3D technology is used to simulate direct flooding experiences at the experiential or sensory level, thereby going beyond traditional persuasion attempts using fear-evoking images. Our results suggest that future communication efforts should not only use these new technologies to transfer knowledge about effective coping strategies and flooding risks, but should especially be directed towards residents living in flood prone areas, but who lack direct flooding experiences as their guiding principle.

Inhalant Use and Inhalant Use Disorders in the United States

PubMed Central

Howard, Matthew O.; Bowen, Scott E.; Garland, Eric L.; Perron, Brian E.; Vaughn, Michael G.

2011-01-01

More than 22 million Americans age 12 and older have used inhalants, and every year more than 750,000 use inhalants for the first time. Despite the substantial prevalence and serious toxicities of inhalant use, it has been termed “the forgotten epidemic.” Inhalant abuse remains the least-studied form of substance abuse, although research on its epidemiology, neurobiology, treatment, and prevention has accelerated in recent years. This review examines current findings in these areas, identifies gaps in the research and clinical literatures pertaining to inhalant use, and discusses future directions for inhalant-related research and practice efforts. PMID:22003419

Increase in Science Research Commitment in a Didactic and Laboratory-Based Program Targeted to Gifted Minority High-School Students

ERIC Educational Resources Information Center

Fraleigh-Lohrfink, Kimberly J.; Schneider, M. Victoria; Whittington, Dawayne; Feinberg, Andrew P.

2013-01-01

Underrepresentation of ethnic minorities in science, technology, engineering, and mathematics (STEM) fields has been a growing concern. Efforts to ameliorate this have often been directed at college-level enrichment. However, mentoring in the sciences at a high-school age level may have a greater impact on career choices. The Center Scholars…

Helwan University Project Developing Primary School Pupils' Abilities and Skills at Some Egyptian Underprivileged Areas (Slums). (Field Study)

ERIC Educational Resources Information Center

El-Tayeb, Mahmoud N.; El Nashar, Mohamed; Zeid, Mai M.; El-Sayed, Magda; Ramadan, Mohamed A.; Hamdi, Safia M.; El-Affy, Nabila; Ebeid, Amina K.; El-Marasi, Sonia S.; Abou-Elmahty, Maher

2010-01-01

Through directing concerted efforts and educational services of seven Faculties of Helwan University towards socially underprivileged pupils in slum areas (EL-Marg area in big Cairo) this research project had two main aims: firstly, modifying a set of arbitrary behaviors of those pupils, in a trial to develop some behavior skills associated with…

The Emerging Worldwide Electronic University: Information Age Global Higher Education. Contributions to the Study of Education, Number 57.

ERIC Educational Resources Information Center

Rossman, Parker

This book proposes an agenda of questions for people who plan for and seek to give some direction to the expanding use of computer conferencing and television for international courses. The book is the first comprehensive effort to gather together and summarize scattered research reports and to report experiments and demonstrations that suggest…

Making Time for Instructional Leadership. Volume 2: The Feasibility of a Randomized Control Trial of the SAM Process

ERIC Educational Resources Information Center

Goldring, Ellen; Grissom, Jason A.; Neumerski, Christine M.; Murphy, Joseph; Blissett, Richard; Porter, Andy

2015-01-01

This three-volume report describes the "SAM (School Administration Manager) process," an approach that about 700 schools around the nation are using to direct more of principals' time and effort to improve teaching and learning in classrooms. Research has shown that a principal's instructional leadership is second only to teaching among…

High School Predictors of College Readiness: Determinants of Developmental Course Enrollment and Second-Year Postsecondary Persistence in Virginia

ERIC Educational Resources Information Center

Garland, Marshall; LaTurner, Jason; Herrera, Angelica Ware; Ware, Anne; Jonas, Deborah; Dougherty, Chrys

2011-01-01

In 2007, the Virginia Board of Education directed the Virginia Department of Education (VDOE) to study academic indicators that are associated with high school students' successful preparation for college and careers. VDOE then embarked on a multi-year effort to identify available data sources and conduct research on high school indicators that…

Science and Technology for a Safer Nation

DTIC Science & Technology

2008-03-01

facilities. “Harvesting Innovation” gathers detailed information about efforts supporting Laboratory-Directed Research and Development ( LDRD ...programs and shares this with DHS directors, division heads and program managers. Energy Department labs allocate some $400 million per year in LDRD ...correlate LDRD projects with DHS S&T strategic goals and ongoing programs as well as planned projects in all six S&T divisions. This minimizes

Framework for Understanding Intercultural Perspective Taking in Operational Settings

DTIC Science & Technology

2016-02-01

Child Development , 42, 1721-1734. Selmeski, B. R. (2007). Military cross-cultural competence: Core concepts and individual development . Centre for...community and can also serve as a common reference for the development community to direct training and assessment initiatives. 15. SUBJECT TERMS...research effort was to develop an understanding of intercultural perspective taking (IPT) in operational settings. To represent this understanding, a

Social Support for Changing Multiple Behaviors: Factors Associated with Seeking Support and the Impact of Offered Support

ERIC Educational Resources Information Center

Greaney, Mary L.; Puleo, Elaine; Sprunck-Harrild, Kim; Haines, Jess; Houghton, Serena C.; Emmons, Karen M.

2018-01-01

Introduction: Social support is important for behavior change, and it may be particularly important for the complexities of changing multiple risk behaviors (MRB). Research is needed to determine if participants in an MRB intervention can be encouraged to activate their social network to aid their change efforts. Methods: Healthy Directions 2, a…

Enhanced Automatic Question Creator--EAQC: Concept, Development and Evaluation of an Automatic Test Item Creation Tool to Foster Modern e-Education

ERIC Educational Resources Information Center

Gutl, Christian; Lankmayr, Klaus; Weinhofer, Joachim; Hofler, Margit

2011-01-01

Research in automated creation of test items for assessment purposes became increasingly important during the recent years. Due to automatic question creation it is possible to support personalized and self-directed learning activities by preparing appropriate and individualized test items quite easily with relatively little effort or even fully…

Least Squares Computations in Science and Engineering

DTIC Science & Technology

1994-02-01

iterative least squares deblurring procedure. Because of the ill-posed characteristics of the deconvolution problem, in the presence of noise , direct...optimization methods. Generally, the problems are accompanied by constraints, such as bound constraints, and the observations are corrupted by noise . The...engineering. This effort has involved interaction with researchers in closed-loop active noise (vibration) control at Phillips Air Force Laboratory

Developing Proactive Methods for General Aviation Data Collection

DTIC Science & Technology

2010-11-01

standard weather package that all pilots would review before flying. 17. Key Words 18. Distribution Statement General Aviation...completed page authorized iii ACKNOWLEDGMENTS We are indebted to the many Flight Standards District Office employees that provided assistance beyond...Directive / Level of Effort Agree- ment between the Human Factors Research and Engineering Group (AJP-61), Flight Standards Service – General Aviation

Self-generated persuasion: effects of the target and direction of arguments.

PubMed

Briñol, Pablo; McCaslin, Michael J; Petty, Richard E

2012-05-01

Previous research has revealed that self-persuasion can occur either through role-playing (i.e., when arguments are generated to convince another person) or, more directly, through trying to convince oneself (i.e., when arguments are generated with oneself as the target). Combining these 2 traditions in the domain of attitude change, the present research investigated the impact on self-persuasion of the specific target of one's own persuasive attempt (i.e., others vs. oneself). We found that the efficacy of self-persuasion depended on whether people believed that they would have to put more or less effort in convincing the self or others. Specifically, we found opposite effects for self-generated arguments depending on whether the topic of persuasion was proattitudinal or counterattitudinal. Across 4 studies, it was shown that when the topic of the message was counterattitudinal, people were more effective in convincing themselves when the intended target of the arguments was themselves versus another person. However, the opposite was the case when the topic was proattitudinal. These effects were shown to stem from the differential effort perceived as necessary and actually exerted in trying to produce persuasion under these conditions.

A review of whole cell wall NMR by the direct-dissolution of biomass

DOE PAGES

Foston, Marcus B.; Samuel, Reichel; He, Jian; ...

2016-01-19

To fully realize the potential of lignocellulosic biomass as a renewable resource for the production of fuels, chemicals, and materials, an improved understanding of the chemical and molecular structures within biomass and how those structures are formed during biosynthesis and transformed during (thermochemical and biological) conversion must be developed. This effort will require analytical techniques which are not only in-depth, rapid, and cost-effective, but also leave native cell wall features intact. Whole plant cell wall nuclear magnetic resonance (NMR) analysis facilitates unparalleled structural characterization of lignocellulosic biomass without causing (or with minimal) structural modification. The objective of this review ismore » to summarize research pertaining to solution- or gel-state whole plant cell wall NMR analysis of biomass, demonstrating the capability of NMR to delineate the structural features and transformations of biomass. In particular, this review will focus on the application of a two-dimensional solution-state NMR technique and perdeuterated ionic liquid based organic electrolyte solvents for the direct dissolution and analysis of biomass. Furthermore, we believe this type of analysis will be critical to advancing biofuel research, improving bioprocessing methodology, and enhancing plant bioengineering efforts.« less

A review of whole cell wall NMR by the direct-dissolution of biomass

DOE Office of Scientific and Technical Information (OSTI.GOV)

Foston, Marcus B.; Samuel, Reichel; He, Jian

To fully realize the potential of lignocellulosic biomass as a renewable resource for the production of fuels, chemicals, and materials, an improved understanding of the chemical and molecular structures within biomass and how those structures are formed during biosynthesis and transformed during (thermochemical and biological) conversion must be developed. This effort will require analytical techniques which are not only in-depth, rapid, and cost-effective, but also leave native cell wall features intact. Whole plant cell wall nuclear magnetic resonance (NMR) analysis facilitates unparalleled structural characterization of lignocellulosic biomass without causing (or with minimal) structural modification. The objective of this review ismore » to summarize research pertaining to solution- or gel-state whole plant cell wall NMR analysis of biomass, demonstrating the capability of NMR to delineate the structural features and transformations of biomass. In particular, this review will focus on the application of a two-dimensional solution-state NMR technique and perdeuterated ionic liquid based organic electrolyte solvents for the direct dissolution and analysis of biomass. Furthermore, we believe this type of analysis will be critical to advancing biofuel research, improving bioprocessing methodology, and enhancing plant bioengineering efforts.« less

Large eddy simulations and direct numerical simulations of high speed turbulent reacting flows

NASA Technical Reports Server (NTRS)

Givi, P.; Frankel, S. H.; Adumitroaie, V.; Sabini, G.; Madnia, C. K.

1993-01-01

The primary objective of this research is to extend current capabilities of Large Eddy Simulations (LES) and Direct Numerical Simulations (DNS) for the computational analyses of high speed reacting flows. Our efforts in the first two years of this research have been concentrated on a priori investigations of single-point Probability Density Function (PDF) methods for providing subgrid closures in reacting turbulent flows. In the efforts initiated in the third year, our primary focus has been on performing actual LES by means of PDF methods. The approach is based on assumed PDF methods and we have performed extensive analysis of turbulent reacting flows by means of LES. This includes simulations of both three-dimensional (3D) isotropic compressible flows and two-dimensional reacting planar mixing layers. In addition to these LES analyses, some work is in progress to assess the extent of validity of our assumed PDF methods. This assessment is done by making detailed companions with recent laboratory data in predicting the rate of reactant conversion in parallel reacting shear flows. This report provides a summary of our achievements for the first six months of the third year of this program.

Cytocompatibility of Direct Laser Interference-patterned Titanium Surfaces for Implants.

PubMed

Hartjen, Philip; Nada, Ola; Silva, Thiago Gundelwein; Precht, Clarissa; Henningsen, Anders; Holthaus, Marzellus GROßE; Gulow, Nikolai; Friedrich, Reinhard E; Hanken, Henning; Heiland, Max; Zwahr, Christoph; Smeets, Ralf; Jung, Ole

2017-01-01

In an effort to generate titanium surfaces for implants with improved osseointegration, we used direct laser interference patterning (DLIP) to modify the surface of pure titanium grade 4 of four different structures. We assessed in vitro cytoxicity and cell attachment, as well as the viability and proliferation of cells cultured directly on the surfaces. Attachment of the cells to the modified surfaces was comparably good compared to that of cells on grit-blasted and acid-etched reference titanium surfaces. In concordance with this, viability and proliferation of the cells directly cultured on the specimens were similar on all the titanium surfaces, regardless of the laser modification, indicating good cytocompatibility. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Nanosensors and nanomaterials for monitoring glucose in diabetes

PubMed Central

Cash, Kevin J.; Clark, Heather A.

2010-01-01

Worldwide, diabetes is a rapidly growing problem that is managed at the individual level by monitoring and controlling blood glucose levels to minimize the negative effects of the disease. Because of limitations in diagnostic methods, significant research efforts are focused on developing improved methods to measure glucose. Nanotechnology has impacted these efforts by increasing the surface area of sensors, improving the catalytic properties of electrodes and providing nanoscale sensors. Herein, we discuss developments in the past several years on both nanosensors that directly measure glucose as well as nanomaterials that improve glucose sensor function. Finally, we discuss challenges that must be overcome to apply these developments in the clinic. PMID:20869318

A Roadmap for caGrid, an Enterprise Grid Architecture for Biomedical Research

PubMed Central

Saltz, Joel; Hastings, Shannon; Langella, Stephen; Oster, Scott; Kurc, Tahsin; Payne, Philip; Ferreira, Renato; Plale, Beth; Goble, Carole; Ervin, David; Sharma, Ashish; Pan, Tony; Permar, Justin; Brezany, Peter; Siebenlist, Frank; Madduri, Ravi; Foster, Ian; Shanbhag, Krishnakant; Mead, Charlie; Hong, Neil Chue

2012-01-01

caGrid is a middleware system which combines the Grid computing, the service oriented architecture, and the model driven architecture paradigms to support development of interoperable data and analytical resources and federation of such resources in a Grid environment. The functionality provided by caGrid is an essential and integral component of the cancer Biomedical Informatics Grid (caBIG™) program. This program is established by the National Cancer Institute as a nationwide effort to develop enabling informatics technologies for collaborative, multi-institutional biomedical research with the overarching goal of accelerating translational cancer research. Although the main application domain for caGrid is cancer research, the infrastructure provides a generic framework that can be employed in other biomedical research and healthcare domains. The development of caGrid is an ongoing effort, adding new functionality and improvements based on feedback and use cases from the community. This paper provides an overview of potential future architecture and tooling directions and areas of improvement for caGrid and caGrid-like systems. This summary is based on discussions at a roadmap workshop held in February with participants from biomedical research, Grid computing, and high performance computing communities. PMID:18560123

A roadmap for caGrid, an enterprise Grid architecture for biomedical research.

PubMed

Saltz, Joel; Hastings, Shannon; Langella, Stephen; Oster, Scott; Kurc, Tahsin; Payne, Philip; Ferreira, Renato; Plale, Beth; Goble, Carole; Ervin, David; Sharma, Ashish; Pan, Tony; Permar, Justin; Brezany, Peter; Siebenlist, Frank; Madduri, Ravi; Foster, Ian; Shanbhag, Krishnakant; Mead, Charlie; Chue Hong, Neil

2008-01-01

caGrid is a middleware system which combines the Grid computing, the service oriented architecture, and the model driven architecture paradigms to support development of interoperable data and analytical resources and federation of such resources in a Grid environment. The functionality provided by caGrid is an essential and integral component of the cancer Biomedical Informatics Grid (caBIG) program. This program is established by the National Cancer Institute as a nationwide effort to develop enabling informatics technologies for collaborative, multi-institutional biomedical research with the overarching goal of accelerating translational cancer research. Although the main application domain for caGrid is cancer research, the infrastructure provides a generic framework that can be employed in other biomedical research and healthcare domains. The development of caGrid is an ongoing effort, adding new functionality and improvements based on feedback and use cases from the community. This paper provides an overview of potential future architecture and tooling directions and areas of improvement for caGrid and caGrid-like systems. This summary is based on discussions at a roadmap workshop held in February with participants from biomedical research, Grid computing, and high performance computing communities.

Some historical trends in the research and development of aircraft

NASA Technical Reports Server (NTRS)

Spearman, M. L.

1983-01-01

A survey of some trends in aircraft design was made in an effort to determine the relation between research, development, test, and evaluation (RDT and E) and aircraft mission capability, requirements, and objectives. Driving forces in the history of aircraft include the quest for speed which involved design concepts incorporating jet propulsion systems and low drag features. The study of high speed design concepts promoted new experimental and analytical research techniques. These research techniques, in turn, have lead to concepts offering new performance potential. Design trends were directed toward increased speed, efficiency, productivity, and safety. Generally speaking, the research and development effort has been evolutionary in nature and, with the exception of the transition to supersonic flight, little has occurred since the origin of flight that has drastically changed the basic design fundamentals of aircraft. However, this does not preclude the possibility of dramatic changes in the future since the products of research are frequently unpredictable. Advances should be expected and sought in improved aerodynamics (reduced drag, enhanced lift, flow field exploitation); propulsion (improved engine cycles, multimode engines, alternate fuels, alternate power sources); structures (new materials, manufacturing techniques); all with a view toward increased efficiency and utility.

Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology

PubMed Central

Yohn, Samantha E.; López-Cruz, Laura; San Miguel, Noemí; Correa, Mercè

2016-01-01

Abstract Motivation has been defined as the process that allows organisms to regulate their internal and external environment, and control the probability, proximity and availability of stimuli. As such, motivation is a complex process that is critical for survival, which involves multiple behavioural functions mediated by a number of interacting neural circuits. Classical theories of motivation suggest that there are both directional and activational aspects of motivation, and activational aspects (i.e. speed and vigour of both the instigation and persistence of behaviour) are critical for enabling organisms to overcome work-related obstacles or constraints that separate them from significant stimuli. The present review discusses the role of brain dopamine and related circuits in behavioural activation, exertion of effort in instrumental behaviour, and effort-related decision-making, based upon both animal and human studies. Impairments in behavioural activation and effort-related aspects of motivation are associated with psychiatric symptoms such as anergia, fatigue, lassitude and psychomotor retardation, which cross multiple pathologies, including depression, schizophrenia, and Parkinson’s disease. Therefore, this review also attempts to provide an interdisciplinary approach that integrates findings from basic behavioural neuroscience, behavioural economics, clinical neuropsychology, psychiatry, and neurology, to provide a coherent framework for future research and theory in this critical field. Although dopamine systems are a critical part of the brain circuitry regulating behavioural activation, exertion of effort, and effort-related decision-making, mesolimbic dopamine is only one part of a distributed circuitry that includes multiple neurotransmitters and brain areas. Overall, there is a striking similarity between the brain areas involved in behavioural activation and effort-related processes in rodents and in humans. Animal models of effort-related decision-making are highly translatable to humans, and an emerging body of evidence indicates that alterations in effort-based decision-making are evident in several psychiatric and neurological disorders. People with major depression, schizophrenia, and Parkinson’s disease show evidence of decision-making biases towards a lower exertion of effort. Translational studies linking research with animal models, human volunteers, and clinical populations are greatly expanding our knowledge about the neural basis of effort-related motivational dysfunction, and it is hoped that this research will ultimately lead to improved treatment for motivational and psychomotor symptoms in psychiatry and neurology. PMID:27189581

Aeropropulsion 1987. Session 6: High-Speed Propulsion Technology

NASA Technical Reports Server (NTRS)

1987-01-01

NASA is conducting aeronautical research over a broad range of Mach numbers. In addition to the advanced CTOL propulsion research described in a separate session, the Lewis Research Center has intensified its efforts towards propulsion technology for selected high-speed flight applications. In a companion program, the Langley Research Center has also accomplished excellent research in Supersonic Combustion Ramjet (SCRAM) propulsion. What is presented in this session is an unclassified review of some of the propulsion research results that are applicable for supersonic to hypersonic vehicles. Not only is a review provided for several key work areas, it also presents a viewpoint on future research directions by calling attention to cycles, components, and facilities involved in this rapidly expanding field of work.

An organizational framework and strategic implementation for system-level change to enhance research-based practice: QUERI Series

PubMed Central

Stetler, Cheryl B; McQueen, Lynn; Demakis, John; Mittman, Brian S

2008-01-01

Background The continuing gap between available evidence and current practice in health care reinforces the need for more effective solutions, in particular related to organizational context. Considerable advances have been made within the U.S. Veterans Health Administration (VA) in systematically implementing evidence into practice. These advances have been achieved through a system-level program focused on collaboration and partnerships among policy makers, clinicians, and researchers. The Quality Enhancement Research Initiative (QUERI) was created to generate research-driven initiatives that directly enhance health care quality within the VA and, simultaneously, contribute to the field of implementation science. This paradigm-shifting effort provided a natural laboratory for exploring organizational change processes. This article describes the underlying change framework and implementation strategy used to operationalize QUERI. Strategic approach to organizational change QUERI used an evidence-based organizational framework focused on three contextual elements: 1) cultural norms and values, in this case related to the role of health services researchers in evidence-based quality improvement; 2) capacity, in this case among researchers and key partners to engage in implementation research; 3) and supportive infrastructures to reinforce expectations for change and to sustain new behaviors as part of the norm. As part of a QUERI Series in Implementation Science, this article describes the framework's application in an innovative integration of health services research, policy, and clinical care delivery. Conclusion QUERI's experience and success provide a case study in organizational change. It demonstrates that progress requires a strategic, systems-based effort. QUERI's evidence-based initiative involved a deliberate cultural shift, requiring ongoing commitment in multiple forms and at multiple levels. VA's commitment to QUERI came in the form of visionary leadership, targeted allocation of resources, infrastructure refinements, innovative peer review and study methods, and direct involvement of key stakeholders. Stakeholders included both those providing and managing clinical care, as well as those producing relevant evidence within the health care system. The organizational framework and related implementation interventions used to achieve contextual change resulted in engaged investigators and enhanced uptake of research knowledge. QUERI's approach and progress provide working hypotheses for others pursuing similar system-wide efforts to routinely achieve evidence-based care. PMID:18510750

Parental reactions to parent- and sibling-directed aggression within a domestic violence context.

PubMed

Desir, Michelle P; Karatekin, Canan

2018-02-01

Parent- and sibling-directed aggression by minor children are two forms of family violence that often co-occur and have strong relations to prior exposure to domestic violence, yet are often overlooked in intervention efforts. In addition, current research does not examine these forms of family violence in tandem, and there is very limited research with samples exposed to domestic violence. To better understand how these forms of aggression operate within a domestic violence context, we interviewed 44 women residing in a domestic violence shelter with at least one child over 3.5 years of age who was aggressive toward them and/or siblings. Caregivers reported on their emotional reactions to children's parent-directed aggression and the types of and effectiveness of help they sought for parent- and/or sibling-directed aggression. In line with previous literature, caregivers endorsed a complex mix of emotional reactions to their children's parent-directed aggression, including anger, sadness, guilt, forgiveness, and worthlessness. In contrast to other studies, most caregivers (89%) had sought help for children's parent- and/or sibling-directed aggression and found it effective. Findings contribute to the literature on parent- and sibling-directed aggression and provide implications for how to effectively intervene.

MARS Mission research center

NASA Technical Reports Server (NTRS)

1991-01-01

The Mars Mission Research Center (M2RC) is one of nine University Space Engineering Research Centers established by NASA in June 1988. It is a cooperative effort between NCSU and A&T in Greensboro. The goal of the Center is to focus on research and educational technologies for planetary exploration with particular emphasis on Mars. The research combines Mission Analysis and Design, Hypersonic Aerodynamics and Propulsion, Structures and Controls, Composite Materials, and Fabrication Methods in a cross-disciplined program directed towards the development of space transportation systems for lunar and planetary travel. The activities of the students and faculty in the M2RC for the period 1 Jul. 1990 to 30 Jun. 1991 are described.

Transdisciplinary translational behavioral (TDTB) research: opportunities, barriers, and innovations.

PubMed

Czajkowski, Susan M; Lynch, Minda R; Hall, Kara L; Stipelman, Brooke A; Haverkos, Lynne; Perl, Harold; Scott, Marcia S; Shirley, Mariela C

2016-03-01

The translation of basic behavioral science discoveries into practical strategies represents a promising approach to developing more effective preventive interventions to improve health. Since translational research inevitably involves making use of diverse perspectives from multiple disciplines, it is best conducted as a transdisciplinary enterprise. In this paper, we discuss current strategies used by NIH to support transdisciplinary translational behavioral (TDTB) research, summarize successful efforts, and highlight challenges encountered in conducting such work (ranging from conceptual to organizational to methodological). Using examples from NIH-funded projects we illustrate the potential benefits of, and barriers to, pursuing this type of research and discuss next steps and potential future directions for NIH-supported TDTB research.

High speed jet noise research at NASA Lewis

NASA Astrophysics Data System (ADS)

Krejsa, Eugene A.; Cooper, B. A.; Kim, C. M.; Khavaran, Abbas

1992-04-01

The source noise portion of the High Speed Research Program at NASA LeRC is focused on jet noise reduction. A number of jet noise reduction concepts are being investigated. These include two concepts, the Pratt & Whitney ejector suppressor nozzle and the General Electric (GE) 2D-CD mixer ejector nozzle, that rely on ejectors to entrain significant amounts of ambient air to mix with the engine exhaust to reduce the final exhaust velocity. Another concept, the GE 'Flade Nozzle' uses fan bypass air at takeoff to reduce the mixed exhaust velocity and to create a fluid shield around a mixer suppressor. Additional concepts are being investigated at Georgia Tech Research Institute and at NASA LeRC. These will be discussed in more detail in later figures. Analytical methods for jet noise prediction are also being developed. Efforts in this area include upgrades to the GE MGB jet mixing noise prediction procedure, evaluation of shock noise prediction procedures, and efforts to predict jet noise directly from the unsteady Navier-Stokes equation.

High speed jet noise research at NASA Lewis

NASA Technical Reports Server (NTRS)

Krejsa, Eugene A.; Cooper, B. A.; Kim, C. M.; Khavaran, Abbas

1992-01-01

The source noise portion of the High Speed Research Program at NASA LeRC is focused on jet noise reduction. A number of jet noise reduction concepts are being investigated. These include two concepts, the Pratt & Whitney ejector suppressor nozzle and the General Electric (GE) 2D-CD mixer ejector nozzle, that rely on ejectors to entrain significant amounts of ambient air to mix with the engine exhaust to reduce the final exhaust velocity. Another concept, the GE 'Flade Nozzle' uses fan bypass air at takeoff to reduce the mixed exhaust velocity and to create a fluid shield around a mixer suppressor. Additional concepts are being investigated at Georgia Tech Research Institute and at NASA LeRC. These will be discussed in more detail in later figures. Analytical methods for jet noise prediction are also being developed. Efforts in this area include upgrades to the GE MGB jet mixing noise prediction procedure, evaluation of shock noise prediction procedures, and efforts to predict jet noise directly from the unsteady Navier-Stokes equation.

A review of turbomachinery blade-row interaction research

NASA Technical Reports Server (NTRS)

Smith, Todd E.

1988-01-01

Analytical and experimental research in the area of unsteady aerodynamics of turbomachinery has conventionally been applied to blading which oscillates when placed in a uniformly flowing fluid. Comparatively less effort has been offered for the study of blading which is subjected to nonuniformities within the flow field. The fluid dynamic environment of a blade-row embedded within multi-stage turbomachines is dominated by such highly unsteady fluid flow conditions. The production of wakes and circumferential pressure variations from adjacent blade-rows causes large unsteady energy transfers between the fluid and the blades. Determination of the forced response of a blade requires the ability to predict the unsteady loads which are induced by these aerodynamic sources. A review of research publications was done to determine recent investigations of the response of turbomachinery blading subjected to aerodynamic excitations. Such excitations are a direct result of the blade-row aerodynamic interaction which occurs between adjacent cascades of blades. The reports and papers reviewed have been organized into areas emphasizing experimental or analytical efforts.

An invitation to contribute to a strategic research agenda in radioecology.

PubMed

Hinton, T G; Garnier-Laplace, J; Vandenhove, H; Dowdall, M; Adam-Guillermin, C; Alonzo, F; Barnett, C; Beaugelin-Seiller, K; Beresford, N A; Bradshaw, C; Brown, J; Eyrolle, F; Fevrier, L; Gariel, J-C; Gilbin, R; Hertel-Aas, T; Horemans, N; Howard, B J; Ikäheimonen, T; Mora, J C; Oughton, D; Real, A; Salbu, B; Simon-Cornu, M; Steiner, M; Sweeck, L; Vives i Batlle, J

2013-01-01

With intentions of integrating a portion of their respective research efforts into a trans-national programme that will enhance radioecology, eight European organisations recently formed the European Radioecology ALLIANCE (www.er-alliance.org). The ALLIANCE is an Association open to other organisations throughout the world with similar interests in promoting radioecology. The ALLIANCE members recognised that their shared radioecological research could be enhanced by efficiently pooling resources among its partner organizations and prioritising group efforts along common themes of mutual interest. A major step in this prioritisation process was to develop a Strategic Research Agenda (SRA). An EC-funded Network of Excellence in Radioecology, called STAR (Strategy for Allied Radioecology), was formed, in part, to develop the SRA. This document is the first published draft of the SRA. The SRA outlines a suggested prioritisation of research topics in radioecology, with the goal of improving research efficiency and more rapidly advancing the science. It responds to the question: "What topics, if critically addressed over the next 20 years, would significantly advance radioecology?" The three Scientific Challenges presented within the SRA, with their 15 associated research lines, are a strategic vision of what radioecology can achieve in the future. Meeting these challenges will require a directed effort and collaboration with many organisations the world over. Addressing these challenges is important to the advancement of radioecology and in providing scientific knowledge to decision makers. Although the development of the draft SRA has largely been a European effort, the hope is that it will initiate an open dialogue within the international radioecology community and its stakeholders. This is an abbreviated document with the intention of introducing the SRA and inviting contributions from interested stakeholders. Critique and input for improving the SRA are welcomed via a link on the STAR website (www.star-radioecology.org). Copyright © 2012 Elsevier Ltd. All rights reserved.

Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities.

PubMed

Pistollato, Francesca; Ohayon, Elan L; Lam, Ann; Langley, Gillian R; Novak, Thomas J; Pamies, David; Perry, George; Trushina, Eugenia; Williams, Robin S B; Roher, Alex E; Hartung, Thomas; Harnad, Stevan; Barnard, Neal; Morris, Martha Clare; Lai, Mei-Chun; Merkley, Ryan; Chandrasekera, P Charukeshi

2016-06-28

Much of Alzheimer disease (AD) research has been traditionally based on the use of animals, which have been extensively applied in an effort to both improve our understanding of the pathophysiological mechanisms of the disease and to test novel therapeutic approaches. However, decades of such research have not effectively translated into substantial therapeutic success for human patients. Here we critically discuss these issues in order to determine how existing human-based methods can be applied to study AD pathology and develop novel therapeutics. These methods, which include patient-derived cells, computational analysis and models, together with large-scale epidemiological studies represent novel and exciting tools to enhance and forward AD research. In particular, these methods are helping advance AD research by contributing multifactorial and multidimensional perspectives, especially considering the crucial role played by lifestyle risk factors in the determination of AD risk. In addition to research techniques, we also consider related pitfalls and flaws in the current research funding system. Conversely, we identify encouraging new trends in research and government policy. In light of these new research directions, we provide recommendations regarding prioritization of research funding. The goal of this document is to stimulate scientific and public discussion on the need to explore new avenues in AD research, considering outcome and ethics as core principles to reliably judge traditional research efforts and eventually undertake new research strategies.

Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities

PubMed Central

Pistollato, Francesca; Ohayon, Elan L.; Lam, Ann; Langley, Gillian R.; Novak, Thomas J.; Pamies, David; Perry, George; Trushina, Eugenia; Williams, Robin S.B.; Roher, Alex E.; Hartung, Thomas; Harnad, Stevan; Barnard, Neal; Morris, Martha Clare; Lai, Mei-Chun; Merkley, Ryan; Chandrasekera, P. Charukeshi

2016-01-01

Much of Alzheimer disease (AD) research has been traditionally based on the use of animals, which have been extensively applied in an effort to both improve our understanding of the pathophysiological mechanisms of the disease and to test novel therapeutic approaches. However, decades of such research have not effectively translated into substantial therapeutic success for human patients. Here we critically discuss these issues in order to determine how existing human-based methods can be applied to study AD pathology and develop novel therapeutics. These methods, which include patient-derived cells, computational analysis and models, together with large-scale epidemiological studies represent novel and exciting tools to enhance and forward AD research. In particular, these methods are helping advance AD research by contributing multifactorial and multidimensional perspectives, especially considering the crucial role played by lifestyle risk factors in the determination of AD risk. In addition to research techniques, we also consider related pitfalls and flaws in the current research funding system. Conversely, we identify encouraging new trends in research and government policy. In light of these new research directions, we provide recommendations regarding prioritization of research funding. The goal of this document is to stimulate scientific and public discussion on the need to explore new avenues in AD research, considering outcome and ethics as core principles to reliably judge traditional research efforts and eventually undertake new research strategies. PMID:27229915

The Design of PC/MISI, a PC-Based Common User Interface to Remote Information Storage and Retrieval Systems. M.S. ThesisFinal Report, 1 Jul. 1985 - 31 Dec. 1987

NASA Technical Reports Server (NTRS)

Dominick, Wayne D. (Editor); Hall, Philip P.

1985-01-01

The amount of information contained in the data bases of large-scale information storage and retrieval systems is very large and growing at a rapid rate. The methods available for assessing this information have not been successful in making the information easily available to the people who have the greatest need for it. This thesis describes the design of a personal computer based system which will provide a means for these individuals to retrieve this data through one standardized interface. The thesis identifies each of the major problems associated with providing access to casual users of IS and R systems and describes the manner in which these problems are to be solved by the utilization of the local processing power of a PC. Additional capabilities, not available with standard access methods, are also provided to improve the user's ability to make use of this information. The design of PC/MISI is intended to facilitate its use as a research vehicle. Evaluation mechanisms and possible areas of future research are described. The PC/MISI development effort is part of a larger research effort directed at improving access to remote IS and R systems. This research effort, supported in part by NASA, is also reviewed.

Review of Global Change Research Program plan

NASA Astrophysics Data System (ADS)

Showstack, Randy

2012-01-01

The draft 10-year strategic plan for the U.S. Global Change Research Program (USGCRP), which proposes broadening the scope of the program from climate change only to climate change and climaterelated global changes, “is an important step in the right direction,” according to a 5 January review of the plan by a committee of the U.S. National Research Council (NRC) of the National Academies. However, the committee also said that the program's legislative mandate is even broader in allowing USGCRP to address many aspects of global change including climate change, the global hydrological cycle, and widespread land use changes. “The Program's legislative mandate is to address all of global change, whether or not related to climate. The Committee concurs that this broader scope is appropriate, but realizes that such an expansion may be constrained by budget realities and by the practical challenge of maintaining clear boundaries for an expanded program,” the report states. “We encourage sustained efforts to expand the Program over time, along with efforts to better define and prioritize what specific topics are included within the bounds of global change research.”

Aerodynamic Database Development for the Hyper-X Airframe Integrated Scramjet Propulsion Experiments

NASA Technical Reports Server (NTRS)

Engelund, Walter C.; Holland, Scott D.; Cockrell, Charles E., Jr.; Bittner, Robert D.

2000-01-01

This paper provides an overview of the activities associated with the aerodynamic database which is being developed in support of NASA's Hyper-X scramjet flight experiments. Three flight tests are planned as part of the Hyper-X program. Each will utilize a small, nonrecoverable research vehicle with an airframe integrated scramjet propulsion engine. The research vehicles will be individually rocket boosted to the scramjet engine test points at Mach 7 and Mach 10. The research vehicles will then separate from the first stage booster vehicle and the scramjet engine test will be conducted prior to the terminal decent phase of the flight. An overview is provided of the activities associated with the development of the Hyper-X aerodynamic database, including wind tunnel test activities and parallel CFD analysis efforts for all phases of the Hyper-X flight tests. A brief summary of the Hyper-X research vehicle aerodynamic characteristics is provided, including the direct and indirect effects of the airframe integrated scramjet propulsion system operation on the basic airframe stability and control characteristics. Brief comments on the planned post flight data analysis efforts are also included.

Life-span effects of ionizing radiation in the beagle dog: A summary account of four decades of research funded by the US Department of Energy and its predecessor agencies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thompson, R.C.

1989-01-01

Nearly 40 years ago, the US Atomic Energy Commission made a far- reaching commitment to the support of life-span radiation-effects studies in a relatively long-lived animal, the beagle dog. Something in the range of 200 million dollars has already been spent on a group of closely related experiments, many of which are only now coming to fruition. Responsible fiscal management of these studies, directed toward securing an optimum return from past investments, and toward creative planning of future directions, requires a comprehensive view of this total effort. This report is designed to provide that comprehensive view. This is primarily intendedmore » as a research management document. Evaluation and interpretation are tasks for those directly involved in conducting these experiments. The limited objective of the present document is to describe what has been done, to give some of the background for why it was done, to describe results already realized and applications that have been made of these results -- all in a manner designed to display the total effort rather than piecemeal details. While proposing no specific answers to the questions ''Where do we go from here.''it is hoped that the document will provide a basis for approaching that question in an informed manner. The maintenance of a continuity of scientific understanding and direction in these experiments, which often continue beyond the initiating investigators' working life, is no small part of the problem involved in conducting these experiments.« less

ADS-33C related handling qualities research performed using the NRC Bell 205 airborne simulator

NASA Technical Reports Server (NTRS)

Morgan, J. Murray; Baillie, Stewart W.

1993-01-01

Over 10 years ago a project was initiated by the U.S. Army AVSCOM to update the military helicopter flying qualities specification MIL-8501-A. While not yet complete, the project reached a major milestone in 1989 with the publication of an Airworthiness Design Standard, ADS-33C. The 8501 update project initially set out to identify critical gaps in the requisite data base and then proceeded to fill them using a variety of directed research studies. The magnitude of the task required that it become an international effort: appropriate research studies were conducted in Germany, the UK and Canada as well as in the USA. Canadian participation was supported by the Department of National Defence (DND) through the Chief of Research and Development. Both ground based and in-flight simulation were used to study the defined areas and the Canadian Bell 205-A1 variable stability helicopter was used extensively as one of the primary research tools available for this effort. This paper reviews the involvement of the Flight Research Laboratory of the National Research Council of Canada in the update project, it describes the various experiments conducted on the Airborne Simulator, it notes significant results obtained and describes ongoing research associated with the project.

NASA and Superalloys: A Customer, a Participant, and a Referee

NASA Technical Reports Server (NTRS)

Nathal, Michael V.

2008-01-01

NASA has had a long history of research and development in the field of superalloys. These efforts have continued today, where the latest advancements in turbine disk and blade technologies are being developed. Although NASA does support military flight systems, its predominant role is in supporting civilian air transportation systems, and thus has goals for improving fuel efficiency, emissions, noise, and safety of today s aircraft. NASA has traditionally served several distinct but complimentary roles as participants in multi-disciplinary research teams, as customers who fund research and development efforts at industry and universities, and as referees who can address broad issues that affect the entire aeronautics community. Because of our longer range viewpoint, we can take on higher risk, higher reward research topics. NASA can also serve as an intermediary between the basic research performed primarily at universities and the development efforts emphasized by industry. By interacting with individual companies, NASA can identify areas of general interest and problems common to a large portion of the aeronautics community, and devise programs aimed at solving these problems. In space missions, NASA is a direct customer responsible for developing vehicles. In the case of the Space Shuttle, NASA has worked with various contractors to design and build numerous components out of superalloys. Another fascinating area for the use of superalloys is in power systems for long life applications in space. Potential missions include providing electric power for deep space missions, surface rovers, including lunar and Mars, and stationary power generators on the lunar surface.

To boost or to CRUNCH? Effect of effortful encoding on episodic memory in older adults is dependent on executive functioning

PubMed Central

Fu, Li; Maes, Joseph H. R.; Kessels, Roy P. C.; Daselaar, Sander M.

2017-01-01

It is essential to develop effective interventions aimed at ameliorating age-related cognitive decline. Previous studies found that effortful encoding benefits episodic memory in older adults. However, to date it is unclear whether this benefit is different for individuals with strong versus weak executive functioning (EF). Fifty-one older adults were recruited and divided into low (N = 26) and high (N = 25) functioning groups, based on their EF capacity. All participants performed a semantic and a perceptual incidental encoding task. Each encoding task was performed under four difficulty levels to establish different effort levels. Encoding was followed by a recognition task. Results showed that the high EF group benefitted from increased effort in both tasks. However, the low EF group only showed a beneficial effect under low levels of effort. Results are consistent with the Compensation-Related Utilization of Neural Circuits Hypothesis (CRUNCH) and suggest that future research directed at developing efficient memory strategies to reduce negative cognitive aging effects should take individual cognitive differences among older adults into account, such as differences in EF. PMID:28328979

Impact of attention biases to threat and effortful control on individual variations in negative affect and social withdrawal in very young children.

PubMed

Cole, Claire E; Zapp, Daniel J; Fettig, Nicole B; Pérez-Edgar, Koraly

2016-01-01

Early temperamental sensitivity may form the basis for the later development of socioemotional maladjustment. In particular, temperamental negative affect places children at risk for the development of anxiety. However, not all children who show negative affect go on to develop anxiety or extreme social withdrawal. Recent research indicates that reactive control, in the form of attention to threat, may serve as a bridge between early temperament and the development of later social difficulties. In addition, variation in effortful control may also modulate this trajectory. Children (mean age=5.57 years) were assessed for attention bias to threatening and pleasant faces using a dot-probe paradigm. Attention bias to threatening (but not happy) faces moderated the direct positive relation between negative affect and social withdrawal. Children with threat biases showed a significant link between negative affect and social withdrawal, whereas children who avoided threat did not. In contrast, effortful control did not moderate the relation between negative affect and social withdrawal. Rather, there was a direct negative relation between effortful control and social withdrawal. The findings from this short report indicate that the relations among temperament, attention bias, and social withdrawal appears early in life and point to early emerging specificity in reactive and regulatory functioning. Copyright © 2015 Elsevier Inc. All rights reserved.

Direct and indirect effects of organizational justice on work ability.

PubMed

Spanier, K; Radoschewski, F M; Gutenbrunner, C; Bethge, M

2014-12-01

Organizational justice (OJ), involving transparent workplace procedures and treating staff members with respect, has been of growing concern in recent epidemiological research as a determinant of health-related outcomes. To examine the factorial validity of the German version of Moorman's Organizational Justice Questionnaire (OJQ), to investigate the direct cross-sectional effect of OJ on self-rated work ability and to analyse if there is an additional indirect effect of OJ on work ability mediated by effort-reward imbalance. An analysis of cross-sectional data from the Second German Sociomedical Panel of Employees, involving white-collar workers employed at least half time. We performed confirmatory factor analyses to test the factorial validity of the OJQ and analysed the direct and indirect associations of OJ and self-rated work ability by path model analysis. Of the 1217 participants (47% female; mean age: 51) 36% had poor work ability. Factor analyses confirmed the two-factor structure of the German OJQ. Work ability was explained directly by OJ (β = 0.30) and effort-reward imbalance (β = -0.27). Additionally, we identified an indirect effect of OJ that was mediated by effort-reward imbalance (β = 0.14). The total effect of OJ on work ability was remarkably strong (β = 0.44). Associations remained unchanged after adjustment for socio-demographic parameters. This study showed the importance of considering additional indirect pathways when examining the impact of OJ on the work ability of employees. © The Author 2014. Published by Oxford University Press on behalf of the Society of Occupational Medicine. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Inferences about landbird abundance from count data: recent advances and future directions

USGS Publications Warehouse

Nichols, J.D.; Thomas, L.; Conn, P.B.; Thomson, David L.; Cooch, Evan G.; Conroy, Michael J.

2009-01-01

We summarize results of a November 2006 workshop dealing with recent research on the estimation of landbird abundance from count data. Our conceptual framework includes a decomposition of the probability of detecting a bird potentially exposed to sampling efforts into four separate probabilities. Primary inference methods are described and include distance sampling, multiple observers, time of detection, and repeated counts. The detection parameters estimated by these different approaches differ, leading to different interpretations of resulting estimates of density and abundance. Simultaneous use of combinations of these different inference approaches can not only lead to increased precision but also provides the ability to decompose components of the detection process. Recent efforts to test the efficacy of these different approaches using natural systems and a new bird radio test system provide sobering conclusions about the ability of observers to detect and localize birds in auditory surveys. Recent research is reported on efforts to deal with such potential sources of error as bird misclassification, measurement error, and density gradients. Methods for inference about spatial and temporal variation in avian abundance are outlined. Discussion topics include opinions about the need to estimate detection probability when drawing inference about avian abundance, methodological recommendations based on the current state of knowledge and suggestions for future research.

Transcending disciplines: Scientific styles in studies of the brain in mid-twentieth century America.

PubMed

Abraham, Tara H

2012-06-01

Much scholarship in the history of cybernetics has focused on the far-reaching cultural dimensions of the movement. What has garnered less attention are efforts by cyberneticians such as Warren McCulloch and Norbert Wiener to transform scientific practice in an array of disciplines in the biomedical sciences, and the complex ways these efforts were received by members of traditional disciplines. In a quest for scientific unity that had a decidedly imperialistic flavour, cyberneticians sought to apply practices common in the exact sciences-mainly theoretical modeling-to problems in disciplines that were traditionally defined by highly empirical practices, such as neurophysiology and neuroanatomy. Their efforts were met with mixed, often critical responses. This paper attempts to make sense of such dynamics by exploring the notion of a scientific style and its usefulness in accounting for the contrasts in scientific practice in brain research and in cybernetics during the 1940s. Focusing on two key institutional contexts of brain research and the role of the Rockefeller and Macy Foundations in directing brain research and cybernetics, the paper argues that the conflicts between these fields were not simply about experiment vs. theory but turned more closely on the questions that defined each area and the language used to elaborate answers. Copyright © 2012 Elsevier Ltd. All rights reserved.

Measurement science and manufacturing science research

NASA Technical Reports Server (NTRS)

Phillips, D. Howard

1987-01-01

The research program of Semiconductor Research Corp. is managed as three overlapping areas: Manufacturing Sciences, Design Sciences and Microstructure Sciences. A total of 40 universities are participating in the performance of over 200 research tasks. The goals and direction of Manufacturing Sciences research became more clearly focused through the efforts of the Manufacturing Sciences Committee of the SRC Technical Advisory Board (TAB). The mission of the SRC Manufacturing Research is the quantification, control, and understanding of semiconductor manufacturing process necessary to achieve a predictable and profitable product output in the competitive environment of the next decade. The 1994 integrated circuit factory must demonstrate a three level hierarchy of control: (1) operation control, (2) process control, and (3) process design. These levels of control are briefly discussed.

Emotion socialization within the family environment and adolescent depression.

PubMed

Schwartz, Orli S; Sheeber, Lisa B; Dudgeon, Paul; Allen, Nicholas B

2012-08-01

This review evaluates research addressing the association between parent-child emotional interactions and the development and maintenance of depression in adolescence, with a focus on studies using observational research methods that assess parental responses to children and adolescents' emotional displays. We argue that parental socialization behaviors in response to different emotions expressed by youths may have distinct associations with depressive outcomes. In particular, parental behaviors that reinforce depressive behavior, reciprocate aggression, and fail to positively reinforce positive behavior have each been associated with youth depression. This review identifies a need for more observational research, including prospective, longitudinal studies, to better understand these behaviors, elucidate the directionality of influence between parental socialization behaviors and youth depression, and more clearly identify protective parental socialization behaviors. However, the use of existing findings to inform family-based interventions may improve prevention and treatment efforts directed at youth depression. Copyright © 2012 Elsevier Ltd. All rights reserved.

NASA/OAI Research Associates program

NASA Technical Reports Server (NTRS)

Keith, Theo G., Jr.

1994-01-01

The intent of this activity was the development of a cooperative program between the Ohio Aerospace Institute and the NASA Lewis Research Center with the objective of better preparing recent university graduates for careers in government aerospace research laboratories. The selected individuals were given the title of research associate. To accomplish the aims of this effort: (1) the research associates were introduced to the NASA Lewis Research Center and its mission/programs, (2) the research associates directly participated in NASA research and development programs, and (3) the research associates were given continuing educational opportunities in specialized areas. A number of individuals participated in this project during the discourse of this cooperative agreement. Attached are the research summaries of eight of the research associates. These reports give a very good picture of the research activities that were conducted by the associates.

Effect of exposure environment on surface decomposition of SiC-silver ion implantation diffusion couples

DOE PAGES

Gerczak, Tyler J.; Zheng, Guiqui; Field, Kevin G.; ...

2014-10-05

SiC is a promising material for nuclear applications and is a critical component in the construction of tristructural isotropic (TRISO) fuel. A primary issue with TRISO fuel operation is the observed release of 110m Ag from intact fuel particles. The release of Ag has prompted research efforts to directly measure the transport mechanism of Ag in bulk SiC. Recent research efforts have focused primarily on Ag ion implantation designs. The effect of the thermal exposure system on the ion implantation surface has been investigated. Results indicate the utilization of a mated sample geometry and the establishment of a static thermalmore » exposure environment is critical to maintaining an intact surface for diffusion analysis. In conclusion, the nature of the implantation surface and its potential role in Ag diffusion analysis are discussed.« less

Self-Uncertainty and the Influence of Alternative Goals on Self-Regulation.

PubMed

Light, Alysson E; Rios, Kimberly; DeMarree, Kenneth G

2018-01-01

The current research examines factors that facilitate or undermine goal pursuit. Past research indicates that attempts to reduce self-uncertainty can result in increased goal motivation. We explore a critical boundary condition of this effect-the presence of alternative goals. Though self-regulatory processes usually keep interest in alternative goals in check, uncertainty reduction may undermine these self-regulatory efforts by (a) reducing conflict monitoring and (b) increasing valuation of alternative goals. As such, reminders of alternative goals will draw effort away from focal goals for self-uncertain (but not self-certain) participants. Across four studies and eight supplemental studies, using different focal goals (e.g., academic achievement, healthy eating) and alternative goals (e.g., social/emotional goals, attractiveness, indulgence), we found that alternative goal salience does not negatively influence goal-directed behavior among participants primed with self-certainty, but that reminders of alternative goals undermine goal pursuit among participants primed with self-uncertainty.

Psychological Issues in Online Adaptive Task Allocation

NASA Technical Reports Server (NTRS)

Morris, N. M.; Rouse, W. B.; Ward, S. L.; Frey, P. R.

1984-01-01

Adaptive aiding is an idea that offers potential for improvement over many current approaches to aiding in human-computer systems. The expected return of tailoring the system to fit the user could be in the form of improved system performance and/or increased user satisfaction. Issues such as the manner in which information is shared between human and computer, the appropriate division of labor between them, and the level of autonomy of the aid are explored. A simulated visual search task was developed. Subjects are required to identify targets in a moving display while performing a compensatory sub-critical tracking task. By manipulating characteristics of the situation such as imposed task-related workload and effort required to communicate with the computer, it is possible to create conditions in which interaction with the computer would be more or less desirable. The results of preliminary research using this experimental scenario are presented, and future directions for this research effort are discussed.

IT Strategic Planning Workshops Develop Long-Term Goals | Poster

Cancer.gov

As part of NCI’s Research IT Strategic Planning efforts, a workshop was held on the NIH main campus in June. The main purpose of the workshop was to discuss ways to better integrate IT and informatics throughout NCI, and develop specific, high-level goals and related objectives that will drive the direction of IT and informatics support over the next five years. The initiative

Structural Integrity of Water Reactor Pressure Boundary Components.

DTIC Science & Technology

1979-12-31

fatigue crack growth is also on-going. Substantial progress in all three of the areas - fatigue data generation, fractography and micromechanism... Fractographie Examinations During the past year, there have been several fractographic studies and fractographically-related research efforts which have been...in the T-L orientation were characterized by a m icrostructural texture running parallel to the macroscopic crack propagation direction (Fig. 31). This

Hypersonic research engine project. Phase 2: Aerothermodynamic integration model development

NASA Technical Reports Server (NTRS)

Jilly, L. F. (Editor)

1970-01-01

The analytical effort was directed towards (1) completing the design of the combustor exit instrumentation assembly, (2) analyzing the coolant flow distribution of the cowl leading edge tip section, (3) determining effects of purge gas pressure on AIM performance analysis, and (4) analyzing heat transfer and associated stress problems related to the cowl leading edge tip section and the nozzle shroud assembly for test conditions.

Information Dissemination and Exchange for Educational Innovations: Conceptual and Implementation Issues of a Regionally-Based Nationwide System. Part Two.

ERIC Educational Resources Information Center

Radnor, Michael; And Others

This volume contains one paper defining the initial operating parameters of the Research and Development Exchange (RDx) and four of a series of papers contracted for the program. The overview paper touches on a variety of topics of continuing concern: the general problems toward which the RDx effort is directed, understandings affecting the design…

High efficiency silicon solar cell review

NASA Technical Reports Server (NTRS)

Godlewski, M. P. (Editor)

1975-01-01

An overview is presented of the current research and development efforts to improve the performance of the silicon solar cell. The 24 papers presented reviewed experimental and analytic modeling work which emphasizes the improvment of conversion efficiency and the reduction of manufacturing costs. A summary is given of the round-table discussion, in which the near- and far-term directions of future efficiency improvements were discussed.

Sense of Direction: The Importance of Helping Community College Students Select and Enter a Program of Study

ERIC Educational Resources Information Center

Moore, Colleen; Shulock, Nancy

2011-01-01

The California Community Colleges (CCC) are committed to increasing the rate at which entering students persist to completion of a certificate or degree or transfer to a university. Recent research suggests that efforts to increase student success in community colleges need to focus on helping new students choose and enter a program of study. Too…

Proceedings of the Thirteenth Annual Precise Time and Time Interval (PTTI) Applications and Planning Meeting

NASA Technical Reports Server (NTRS)

Wardrip, S. C.

1982-01-01

Proceedings of an annual Precise Time and Time Interval (PTTI) Applications and Planning Meeting are summarized. A transparent view of the state-of-the-art, an opportunity to express needs, a view of important future trends, and a review of relevant past accomplishments were considered for PTTI managers, systems engineers, and program planner. Specific aims were: to provide PTTI users with new and useful applications, procedures, and techniques; to allow the PTTI researcher to better assess fruitful directions for research efforts.

PNT Activities at NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Sands, Obed

2017-01-01

This presentation provides a review of Position Navigation and Timing activities at the Glenn Research Center. Topics include 1) contributions to simulation studies for the Space Service Volume of the Global Navigation Satellite System, 2) development and integration efforts for a Software Defined Radio (SDR) waveform for the Space Communications and Navigation (SCaN) testbed, currently onboard the International Space Station and 3) a GPS L5 testbed intended to explore terrain mapping capabilities with communications signals. Future directions are included and a brief discussion of NASA, GRC and the SCAN office.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heroux, Michael Allen; Marker, Bryan

This report summarizes the progress made as part of a one year lab-directed research and development (LDRD) project to fund the research efforts of Bryan Marker at the University of Texas at Austin. The goal of the project was to develop new techniques for automatically tuning the performance of dense linear algebra kernels. These kernels often represent the majority of computational time in an application. The primary outcome from this work is a demonstration of the value of model driven engineering as an approach to accurately predict and study performance trade-offs for dense linear algebra computations.

A new vision for the study of benign prostate disease: the NIDDK Prostate Research Strategic Plan.

PubMed

Mullins, Chris; Kaplan, Steven A

2009-03-01

The American population continues to enjoy a steady increase in life expectancy. A major goal for this population is to maintain and improve quality of life as it ages. For men a major source of age related health burden is benign disorders of the prostate which, despite much research, remain poorly defined and require greater advancement in prevention and treatment. Thus, there is a substantial need to develop a long-range vision to focus and promote efforts to better understand and manage benign prostate disease. In response the National Institute of Diabetes and Digestive and Kidney Diseases convened a panel of key opinion leaders including basic researchers, translational scientists, epidemiologists, and clinicians and clinical researchers to develop a comprehensive strategic plan to advance research in benign prostate disease. The overall mission statement of this effort is "To discuss, evaluate, and propose research needs and a long-range research agenda (ie a strategic plan) for NIDDK grant portfolios related to research into benign prostate disease." Implementation and practical application of this strategic plan will require a partnership of the scientific community, the Federal Government, and other public and private organizations and institutions. This focused group of research and thought leaders identified 4 major areas of key significance for future investigation: basic science, epidemiology/population based studies, translational opportunities and clinical sciences. Great opportunities are identified within these 4 areas to develop new insights, and translate findings for benign prostate diseases and related syndromes between the research laboratory and the clinical setting. The product of these efforts, the National Institute of Diabetes and Digestive and Kidney Diseases Prostate Research Strategic Plan, represents a blueprint that researchers and Federal Government can use to review where the field has been, define where the field is and, most importantly, identify where and how future research efforts should be directed. To accomplish this goal many priorities must be addressed, including the need to create more effective lines of communication among scientific disciplines to improve translation of research findings and ultimately advance patient treatment. The overall goals and missions of the National Institute of Diabetes and Digestive and Kidney Diseases Prostate Research Strategic Plan, along with key scientific recommendations and priorities for the major areas of focus, are summarized.

Eukaryotic Chemotaxis

PubMed Central

Rappel, Wouter-Jan; Loomis, William F.

2009-01-01

During eukaryotic chemotaxis, external chemical gradients guide the crawling motion of cells. This process plays an important role in a large variety of biological systems and has wide ranging medical implications. New experimental techniques including confocal microscopy and microfluidics have advanced our understanding of chemotaxis while numerical modeling efforts are beginning to offer critical insights. In this short review, we survey the current experimental status of the field by dividing chemotaxis into three distinct “modules”: directional sensing, polarity and motility. For each module, we attempt to point out potential new directions of research and discuss how modeling studies interact with experimental investigations. PMID:20648241

Timeline: Targeted Treatment of Hepatitis C Virus.

PubMed

Teitzel, Gail

2016-09-22

Chronic hepatitis C virus infection can cause liver cirrhosis and cancer, and early treatment options were non-specific and could be toxic. Work aimed at elucidating the viral life cycle has led to better treatment options through the development of direct-acting antivirals, as exemplified by the work of Ralf Bartenschlager, Charles Rice, and Michael Sofia who have received the Lasker∼DeBakey Clinical Medical Research Award for their work on this effort. Key events in understanding HCV replication and development of direct-acting antivirals are shown in this Timeline. Copyright © 2016 Elsevier Inc. All rights reserved.

Red Wolf (Canis rufus) Recovery: A Review with Suggestions for Future Research

PubMed Central

Hinton, Joseph W.; Chamberlain, Michael J.; Rabon, David R.

2013-01-01

Simple Summary Once widespread in the Eastern United States, early 20th century predator-control programs reduced red wolves to a remnant population by the 1970s. The U.S. Fish and Wildlife Service, through the Red Wolf Recovery Program, restored red wolves to northeastern North Carolina in 1987. After 25 years of restoration efforts, issues of hybridization with coyotes, inbreeding, and human-caused mortality continue to hamper red wolf recovery. To understand how these issues influence recovery efforts, we examine the history of red wolf restoration and its challenges. We then formulate areas of research that are of direct relevance to the restoration of red wolves. Abstract By the 1970s, government-supported eradication campaigns reduced red wolves to a remnant population of less than 100 individuals on the southern border of Texas and Louisiana. Restoration efforts in the region were deemed unpromising because of predator-control programs and hybridization with coyotes. The U.S. Fish and Wildlife Service (USFWS) removed the last remaining red wolves from the wild and placed them in a captive-breeding program. In 1980, the USFWS declared red wolves extinct in the wild. During 1987, the USFWS, through the Red Wolf Recovery Program, reintroduced red wolves into northeastern North Carolina. Although restoration efforts have established a population of approximately 70–80 red wolves in the wild, issues of hybridization with coyotes, inbreeding, and human-caused mortality continue to hamper red wolf recovery. We explore these three challenges and, within each challenge, we illustrate how research can be used to resolve problems associated with red wolf-coyote interactions, effects of inbreeding, and demographic responses to human-caused mortality. We hope this illustrates the utility of research to advance restoration of red wolves. PMID:26479530

A brief overview of NASA Langley's research program in formal methods

NASA Technical Reports Server (NTRS)

1992-01-01

An overview of NASA Langley's research program in formal methods is presented. The major goal of this work is to bring formal methods technology to a sufficiently mature level for use by the United States aerospace industry. Towards this goal, work is underway to design and formally verify a fault-tolerant computing platform suitable for advanced flight control applications. Also, several direct technology transfer efforts have been initiated that apply formal methods to critical subsystems of real aerospace computer systems. The research team consists of six NASA civil servants and contractors from Boeing Military Aircraft Company, Computational Logic Inc., Odyssey Research Associates, SRI International, University of California at Davis, and Vigyan Inc.

Toward a Modern Science of Obesity at Washington University: How We Do It and What is the Payoff?

PubMed

Colditz, Graham A; Gehlert, Sarah; Bowen, Deborah J; Carson, Kenneth; Hovmand, Peter S; Lee, Jung Ae; Moley, Kelle H

2016-07-01

In our Cancer Prevention Program at Washington University in Saint Louis (WUSTL), we have made extraordinary efforts to create the kind of cancer prevention and control program that is both translational and transdisciplinary in nature, to accelerate the march from basic discoveries to population change. Here we present an overview of our obesity-related research currently ongoing in our Center, paying particular attention to both the translational- transdisciplinary process and to community-based participatory research. We end with our future directions for improving obesity-related cancer outcomes research. Cancer Prev Res; 9(7); 503-8. ©2016 AACR. ©2016 American Association for Cancer Research.

NASA/Goddard Thermal Technology Overview 2014

NASA Technical Reports Server (NTRS)

Butler, Daniel; Swanson, Theodore D.

2014-01-01

This presentation summarizes the current plans and efforts at NASA Goddard to develop new thermal control technology for anticipated future missions. It will also address some of the programmatic developments currently underway at NASA, especially with respect to the Technology Development Program at NASA. While funding for basic technology development is still scarce, significant efforts are being made in direct support of flight programs. New technology development continues to be driven by the needs of future missions, and applications of these technologies to current Goddard programs will be addressed. Many of these technologies also have broad applicability to DOD, DOE, and commercial programs. Partnerships have been developed with the Air Force, Navy, and various universities to promote technology development. In addition, technology development activities supported by internal research and development (IRAD) program, the Small Business Innovative Research (SBIR) program, and the NASA Engineering and Safety Center (NESC), are reviewed in this presentation. Specific technologies addressed include; two-phase systems applications and issues on NASA missions, latest developments of electro-hydrodynamically pumped systems, development of high electrical conductivity coatings, and various other research activities. New Technology program underway at NASA, although funding is limited center dot NASA/GSFC's primary mission of science satellite development is healthy and vibrant, although new missions are scarce - now have people on overhead working new missions and proposals center dot Future mission applications promise to be thermally challenging center dot Direct technology funding is still very restricted - Projects are the best source for direct application of technology - SBIR thermal subtopic resurrected in FY 14 - Limited Technology development underway via IRAD, NESC, other sources - Administrator pushing to revive technology and educational programs at NASA - new HQ directorate established

A survey of keystroke dynamics biometrics.

PubMed

Teh, Pin Shen; Teoh, Andrew Beng Jin; Yue, Shigang

2013-01-01

Research on keystroke dynamics biometrics has been increasing, especially in the last decade. The main motivation behind this effort is due to the fact that keystroke dynamics biometrics is economical and can be easily integrated into the existing computer security systems with minimal alteration and user intervention. Numerous studies have been conducted in terms of data acquisition devices, feature representations, classification methods, experimental protocols, and evaluations. However, an up-to-date extensive survey and evaluation is not yet available. The objective of this paper is to provide an insightful survey and comparison on keystroke dynamics biometrics research performed throughout the last three decades, as well as offering suggestions and possible future research directions.

NASA Nebraska Space Grant Consortium 1995-1999 Self Evaluation

NASA Technical Reports Server (NTRS)

Schaaf, Michaela M.; Bowen, Brent D.; Schaffart, Mary M.

1999-01-01

The NASA Nebraska Space Grant Consortium receives funds from NASA to allow Nebraska colleges and universities to implement balanced programs of research, education and public service related to aeronautics, space science and technology. Nebraska is a capability enhancement state which directs efforts and resources toward developing research infrastructure and enhancing the quality of aerospace research and education for all Nebraskans. Furthermore, the Nebraska Space Grant strives to provide national leadership in applied aspects of aeronautics. Nebraska has met, meets and will continue to meet all requirements set forth by NASA. Nebraska is a top-tier consortium and will continue to be a model program.

Summary of NACA Research on Afterburners for Turbojet Engines

NASA Technical Reports Server (NTRS)

Lundin, Bruce T; Gabriel, David S; Fleming, William A

1956-01-01

NACA research on afterburners for turbojet engines during the past 5 years is summarized. Although most of this work has been directed toward the development of specific afterburners for various engines rather than toward the accumulation of systematic data, it has, nevertheless, provided a large fund of experimental data and experience in the field. The references cited present over 1000 afterburner configurations and some 3500 hours of operation. In the treatment of the material of this summary, the principal effort has been to convey to the reader the "know-how" acquired by research engineers in the course of the work rather than to formulate a set of design rules.

Discovery of direct inhibitors of Keap1-Nrf2 protein-protein interaction as potential therapeutic and preventive agents.

PubMed

Abed, Dhulfiqar Ali; Goldstein, Melanie; Albanyan, Haifa; Jin, Huijuan; Hu, Longqin

2015-07-01

The Keap1-Nrf2-ARE pathway is an important antioxidant defense mechanism that protects cells from oxidative stress and the Keap1-Nrf2 protein-protein interaction (PPI) has become an important drug target to upregulate the expression of ARE-controlled cytoprotective oxidative stress response enzymes in the development of therapeutic and preventive agents for a number of diseases and conditions. However, most known Nrf2 activators/ARE inducers are indirect inhibitors of Keap1-Nrf2 PPI and they are electrophilic species that act by modifying the sulfhydryl groups of Keap1׳s cysteine residues. The electrophilicity of these indirect inhibitors may cause "off-target" side effects by reacting with cysteine residues of other important cellular proteins. Efforts have recently been focused on the development of direct inhibitors of Keap1-Nrf2 PPI. This article reviews these recent research efforts including the development of high throughput screening assays, the discovery of peptide and small molecule direct inhibitors, and the biophysical characterization of the binding of these inhibitors to the target Keap1 Kelch domain protein. These non-covalent direct inhibitors of Keap1-Nrf2 PPI could potentially be developed into effective therapeutic or preventive agents for a variety of diseases and conditions.

LDRD final report on massively-parallel linear programming : the parPCx system.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parekh, Ojas; Phillips, Cynthia Ann; Boman, Erik Gunnar

2005-02-01

This report summarizes the research and development performed from October 2002 to September 2004 at Sandia National Laboratories under the Laboratory-Directed Research and Development (LDRD) project ''Massively-Parallel Linear Programming''. We developed a linear programming (LP) solver designed to use a large number of processors. LP is the optimization of a linear objective function subject to linear constraints. Companies and universities have expended huge efforts over decades to produce fast, stable serial LP solvers. Previous parallel codes run on shared-memory systems and have little or no distribution of the constraint matrix. We have seen no reports of general LP solver runsmore » on large numbers of processors. Our parallel LP code is based on an efficient serial implementation of Mehrotra's interior-point predictor-corrector algorithm (PCx). The computational core of this algorithm is the assembly and solution of a sparse linear system. We have substantially rewritten the PCx code and based it on Trilinos, the parallel linear algebra library developed at Sandia. Our interior-point method can use either direct or iterative solvers for the linear system. To achieve a good parallel data distribution of the constraint matrix, we use a (pre-release) version of a hypergraph partitioner from the Zoltan partitioning library. We describe the design and implementation of our new LP solver called parPCx and give preliminary computational results. We summarize a number of issues related to efficient parallel solution of LPs with interior-point methods including data distribution, numerical stability, and solving the core linear system using both direct and iterative methods. We describe a number of applications of LP specific to US Department of Energy mission areas and we summarize our efforts to integrate parPCx (and parallel LP solvers in general) into Sandia's massively-parallel integer programming solver PICO (Parallel Interger and Combinatorial Optimizer). We conclude with directions for long-term future algorithmic research and for near-term development that could improve the performance of parPCx.« less

Examination of Wildland Fire Spread at Small Scales Using Direct Numerical Simulations and High-Speed Laser Diagnostics

NASA Astrophysics Data System (ADS)

Wimer, N. T.; Mackoweicki, A. S.; Poludnenko, A. Y.; Hoffman, C.; Daily, J. W.; Rieker, G. B.; Hamlington, P.

2017-12-01

Results are presented from a joint computational and experimental research effort focused on understanding and characterizing wildland fire spread at small scales (roughly 1m-1mm) using direct numerical simulations (DNS) with chemical kinetics mechanisms that have been calibrated using data from high-speed laser diagnostics. The simulations are intended to directly resolve, with high physical accuracy, all small-scale fluid dynamic and chemical processes relevant to wildland fire spread. The high fidelity of the simulations is enabled by the calibration and validation of DNS sub-models using data from high-speed laser diagnostics. These diagnostics have the capability to measure temperature and chemical species concentrations, and are used here to characterize evaporation and pyrolysis processes in wildland fuels subjected to an external radiation source. The chemical kinetics code CHEMKIN-PRO is used to study and reduce complex reaction mechanisms for water removal, pyrolysis, and gas phase combustion during solid biomass burning. Simulations are then presented for a gaseous pool fire coupled with the resulting multi-step chemical reaction mechanisms, and the results are connected to the fundamental structure and spread of wildland fires. It is anticipated that the combined computational and experimental approach of this research effort will provide unprecedented access to information about chemical species, temperature, and turbulence during the entire pyrolysis, evaporation, ignition, and combustion process, thereby permitting more complete understanding of the physics that must be represented by coarse-scale numerical models of wildland fire spread.

Lessons from comparative effectiveness research methods development projects funded under the Recovery Act.

PubMed

Zurovac, Jelena; Esposito, Dominick

2014-11-01

The American Recovery and Reinvestment Act of 2009 (ARRA) directed nearly US$29.2 million to comparative effectiveness research (CER) methods development. To help inform future CER methods investments, we describe the ARRA CER methods projects, identify barriers to this research and discuss the alignment of topics with published methods development priorities. We used several existing resources and held discussions with ARRA CER methods investigators. Although funded projects explored many identified priority topics, investigators noted that much work remains. For example, given the considerable investments in CER data infrastructure, the methods development field can benefit from additional efforts to educate researchers about the availability of new data sources and about how best to apply methods to match their research questions and data.

The Effects of Directional Processing on Objective and Subjective Listening Effort

ERIC Educational Resources Information Center

Picou, Erin M.; Moore, Travis M.; Ricketts, Todd A.

2017-01-01

Purpose: The purposes of this investigation were (a) to evaluate the effects of hearing aid directional processing on subjective and objective listening effort and (b) to investigate the potential relationships between subjective and objective measures of effort. Method: Sixteen adults with mild to severe hearing loss were tested with study…

Determinants of individual and group performance

NASA Technical Reports Server (NTRS)

Helmreich, Robert L.

1986-01-01

A broad exploration of individual and group/organizational factors that influence performance in demanding environments such as space and air transport was undertaken. Primary efforts were directed toward defining critical issues, developing new methodologies for the assessment of performance in such environments, and developing new measures of personality and attitudes as predictors of performance. Substantial clarification of relevant issues for research and validation was achieved. A reliable instrument to assess crewmembers' attitudes regarding crew coordination and flightdeck management was validated. Major efforts in data collection to validate concepts were initiated. The results suggest that substantial improvements can be made in the prediction of performance and in the selection of crewmembers for aviation and space.

Implicit theory of athletic ability and self-handicapping in college students.

PubMed

Chen, Lung Hung; Chen, Mei-Yen; Lin, Meng-Shyan; Kee, Ying Hwa; Kuo, Chin Fang; Shui, Shang-Hsueh

2008-10-01

Self-handicapping is a maladaptive behavior which undermines students' achievements, but the antecedents of self-handicapping are not well studied in physical education. The aim was to examine the relations of implicit theory of abilities and self-handicapping in physical education. 264 college students, whose mean age was 20.3 yr. (SD = 1.7), completed the Conceptions of the Nature of Athletic Ability Questionnaire-2 and Self-handicapping Scale for Sport. Analysis indicated entity beliefs positively predicted reduced effort and making excuses. Also, incremental beliefs negatively predicted reduced effort. Results are discussed in terms of implicit theory of ability and self-handicapping. Directions for research and implications are stated.

Nanosensors and nanomaterials for monitoring glucose in diabetes.

PubMed

Cash, Kevin J; Clark, Heather A

2010-12-01

Worldwide, diabetes is a rapidly growing problem that is managed at the individual level by monitoring and controlling blood glucose levels to minimize the negative effects of the disease. Because of limitations in diagnostic methods, significant research efforts are focused on developing improved methods to measure glucose. Nanotechnology has impacted these efforts by increasing the surface area of sensors, improving the catalytic properties of electrodes and providing nanoscale sensors. Here, we discuss developments in the past several years on both nanosensors that directly measure glucose and nanomaterials that improve glucose sensor function. Finally, we discuss challenges that must be overcome to apply these developments in the clinic. Copyright © 2010 Elsevier Ltd. All rights reserved.

The National Science Foundation CAREER Award: A Unique Solution to the Challenges of the Tenure Process

NASA Astrophysics Data System (ADS)

Fouch, M. J.

2011-12-01

There is a dichotomy inherent in the tenure process at most research-strong universities. Most institutions require strong performance in research production and grant acquisition, while at the same time very good to excellent teaching performance. However, in the first several years of the tenure process, many new faculty spend most of their time preparing lectures for new classes and writing grant proposals, leaving little time to forge new directions and define their individual paths in their research, which, somewhat ironically, is the primary factor by which tenure is either granted or denied. The CAREER grant is a unique solution to this problem, as it enables beginning faculty members to directly thread their research into their teaching, and vice versa. My CAREER award, the first granted by the (at the time) fledgling EarthScope Science program at NSF, enabled me to bring EarthScope data and science directly into the classroom. One cadre of efforts was a focus on software development, which is a critical roadblock in geophysics for students who do not have extensive experience with Unix-based coding. For example, Kevin Eagar developed the MATLAB-based FuncLab software system that enables one to quickly and efficiently analyze receiver functions, allowing one to image layers within Earth's interior, such as the crust-mantle boundary. This system is now publically available at http://geophysics.asu.edu/funclab. At Arizona State University, 5 undergraduate students and 2 graduate students have already used this software package to produce publishable scientific results over the past 2 years, enabling them to experience research firsthand and learn a range of key research skills for their future endeavors. The CAREER award also provided ample opportunities for my research group and me to forge into new research directions given the broad scope of the proposed work. Ultimately, this freedom has led to a number of new and exciting results regarding the nature of deformation in Earth's crust, Earth's response to moderate sized earthquakes occurring hundreds of kilometers away, and further new software development to handle these new, massive, datasets provided by the EarthScope program. The culmination of these efforts allowed me a much smoother path toward tenure, given that the CAREER grant enabled new directions and production through integration of my teaching and research (as well as my national service to the EarthScope program). The challenges to this integration were quite modest given that I was able to fold my group's research directly into some of my teaching. Finally, while the program is very good at present, I will present a few ideas for program improvement. For example, it is essential that NSF continue to fully inform and educate peer reviewers of the special nature of CAREER awards, since it is a major challenge for most reviewers to fully and adequately judge both research and teaching. Further, because of the unique nature of the CAREER proposal, NSF might consider extending the length of the proposal by 2-3 pages to provide additional room for extended project timelines, etc.

Electronic Records, Registries, and the Development of "Big Data": Crowd-Sourcing Quality toward Knowledge.

PubMed

Dewdney, Summer B; Lachance, Jason

2016-01-01

Despite many perceived advances in treatment over the past few decades, cancer continues to present a significant health burden, particularly to the aging US population. Forces including shrinking funding mechanisms, cost and quality concerns, as well as disappointing clinical outcomes have driven a surge of recent efforts into utilizing the technological innovation that has permeated other industries by leveraging large and complex data sets, so called "big data." In this review, we will review some of the history of oncology data collection, including the earliest data registries, as well as explore the future directions of this new brand of research while highlighting some of the more recent and promising efforts to harness the power of the electronic health record and the multitude of data co-located there, in an effort to improve individualized cancer-related outcomes in rapid real time.

Minimising visitor impacts to protected areas: The efficacy of low impact education programmes

USGS Publications Warehouse

Marion, J.L.; Reid, S.E.

2007-01-01

Protected area managers, tourism providers, and other organisations commonly employ education programmes to address visitation-related impairment of natural and cultural resources, social conditions, and neighbouring communities. These programmes have different names (Leave No Trace, Codes of Conduct, Environmental Guidelines for Tourists) but share common objectives: to sustain opportunities for high quality visitor experiences while avoiding or minimising associated negative impacts to protected area resources, visitor experiences, and park neighbours. Theoretical and empirical research studies in the United States are reviewed to evaluate the efficacy of educational efforts that seek to encourage adoption of low impact behaviours. Findings reveal that most of the visitor education efforts evaluated did effectively alter visitor knowledge, behaviour and/or resource and social conditions in the intended direction. These findings, including discussions of message content, delivery, audience characteristics and theoretical grounding, provide insights for improving the efficacy of future educational efforts.

Biomolecular damage induced by ionizing radiation: the direct and indirect effects of low-energy electrons on DNA.

PubMed

Alizadeh, Elahe; Orlando, Thomas M; Sanche, Léon

2015-04-01

Many experimental and theoretical advances have recently allowed the study of direct and indirect effects of low-energy electrons (LEEs) on DNA damage. In an effort to explain how LEEs damage the human genome, researchers have focused efforts on LEE interactions with bacterial plasmids, DNA bases, sugar analogs, phosphate groups, and longer DNA moieties. Here, we summarize the current understanding of the fundamental mechanisms involved in LEE-induced damage of DNA and complex biomolecule films. Results obtained by several laboratories on films prepared and analyzed by different methods and irradiated with different electron-beam current densities and fluencies are presented. Despite varied conditions (e.g., film thicknesses and morphologies, intrinsic water content, substrate interactions, and extrinsic atmospheric compositions), comparisons show a striking resemblance in the types of damage produced and their yield functions. The potential of controlling this damage using molecular and nanoparticle targets with high LEE yields in targeted radiation-based cancer therapies is also discussed.

Activating analytic thinking enhances the value given to individualizing moral foundations.

PubMed

Yilmaz, Onurcan; Saribay, S Adil

2017-08-01

Two central debates within Moral Foundations Theory concern (1) which moral foundations are core and (2) how conflict between ideological camps stemming from valuing different moral foundations can be resolved. Previous studies have attempted to answer the first question by imposing cognitive load on participants to direct them toward intuitive and automatic thought. However, this method has limitations and has produced mixed findings. In the present research, in two experiments, instead of directing participants toward intuitive thought, we tested the effects of activating high-effort, analytic thought on participants' moral foundations. In both experiments, analytic thought activation caused participants to value individualizing foundations greater than the control condition. This effect was not qualified by participants' political orientation. No effect was observed on binding foundations. The results are consistent with the idea that upholding individualizing foundations requires mental effort and may provide the basis for reconciliation between different ideological camps. Copyright © 2017 Elsevier B.V. All rights reserved.

NASA's First Year Progress with Fuel Cell Advanced Development in Support of the Exploration Vision

NASA Technical Reports Server (NTRS)

Hoberecht, Mark

2007-01-01

NASA Glenn Research Center (GRC), in collaboration with Johnson Space Center (JSC), the Jet Propulsion Laboratory (JPL), Kennedy Space Center (KSC), and industry partners, is leading a proton-exchange-membrane fuel cell (PEMFC) advanced development effort to support the vision for Exploration. This effort encompasses the fuel cell portion of the Energy Storage Project under the Exploration Technology Development Program, and is directed at multiple power levels for both primary and regenerative fuel cell systems. The major emphasis is the replacement of active mechanical ancillary components with passive components in order to reduce mass and parasitic power requirements, and to improve system reliability. A dual approach directed at both flow-through and non flow-through PEMFC system technologies is underway. A brief overview of the overall PEMFC project and its constituent tasks will be presented, along with in-depth technical accomplishments for the past year. Future potential technology development paths will also be discussed.

Geometric-Optical Modeling of Directional Thermal Radiance for Improvement of Land Surface Temperature Retrievals from MODIS, ASTER, and Landsat-7 Instruments

NASA Technical Reports Server (NTRS)

Li, Xiaowen; Friedl, Mark; Strahler, Alan

2002-01-01

The general objectives of this project were to improve understanding of the directional emittance properties of land surfaces in the thermal infrared (TIR) region of the electro-magnetic spectrum. To accomplish these objectives our research emphasized a combination of theoretical model development and empirical studies designed to improve land surface temperature (LST) retrievals from space-borne remote sensing instruments. Following the proposal, the main tasks for this project were to: (1) Participate in field campaigns; (2) Acquire and process field, aircraft, and ancillary data; (3) Develop and refine models of LST emission; (4) Develop algorithms for LST retrieval; and (5) Explore LST retrieval methods for use in energy balance models. In general all of these objectives were addressed, and for the most part achieved. The main results from this project are described in the publications arising from this effort. We summarize our efforts related to each of the objectives.

Intelligent behaviors through vehicle-to-vehicle and vehicle-to-infrastructure communication

NASA Astrophysics Data System (ADS)

Garcia, Richard D.; Sturgeon, Purser; Brown, Mike

2012-06-01

The last decade has seen a significant increase in intelligent safety devices on private automobiles. These devices have both increased and augmented the situational awareness of the driver and in some cases provided automated vehicle responses. To date almost all intelligent safety devices have relied on data directly perceived by the vehicle. This constraint has a direct impact on the types of solutions available to the vehicle. In an effort to improve the safety options available to a vehicle, numerous research laboratories and government agencies are investing time and resources into connecting vehicles to each other and to infrastructure-based devices. This work details several efforts in both the commercial vehicle and the private auto industries to increase vehicle safety and driver situational awareness through vehicle-to-vehicle and vehicle-to-infrastructure communication. It will specifically discuss intelligent behaviors being designed to automatically disable non-compliant vehicles, warn tractor trailer vehicles of unsafe lane maneuvers such as lane changes, passing, and merging, and alert drivers to non-line-of-sight emergencies.

Engaging Communities in Identifying Local Strategies for Expanding Integrated Employment During and After High School.

PubMed

Carter, Erik W; Blustein, Carly L; Bumble, Jennifer L; Harvey, Sarah; Henderson, Lynnette M; McMillan, Elise D

2016-09-01

Amidst decades of attention directed toward improving employment outcomes for people with intellectual and developmental disabilities (IDD), few efforts have been made to engage communities in identifying local solutions for expanding integrated employment opportunities. We examined the implementation and outcomes of "community conversation" events held in 6 geographically and economically diverse locales. Each event used an asset-based dialogue approach called the World Café ( Brown & Isaacs, 2005 ) to solicit ideas from a broad cross-section of community members on improving integrated employment that reflect local priorities and possibilities. Six key themes encapsulated the 1,556 strategies generated by the almost 400 attendees. Although considerable consistency was found among the categories of strategies raised across events, the manner in which those individual strategies would be implemented locally reflected the unique accent of each community. Attendees also viewed these events as promising and productive pathways for identifying next steps for their community. We offer recommendations for community-level intervention efforts and suggest directions for future research.

The Pathologist Workforce in the United States: II. An Interactive Modeling Tool for Analyzing Future Qualitative and Quantitative Staffing Demands for Services.

PubMed

Robboy, Stanley J; Gupta, Saurabh; Crawford, James M; Cohen, Michael B; Karcher, Donald S; Leonard, Debra G B; Magnani, Barbarajean; Novis, David A; Prystowsky, Michael B; Powell, Suzanne Z; Gross, David J; Black-Schaffer, W Stephen

2015-11-01

Pathologists are physicians who make diagnoses based on interpretation of tissue and cellular specimens (surgical/cytopathology, molecular/genomic pathology, autopsy), provide medical leadership and consultation for laboratory medicine, and are integral members of their institutions' interdisciplinary patient care teams. To develop a dynamic modeling tool to examine how individual factors and practice variables can forecast demand for pathologist services. Build and test a computer-based software model populated with data from surveys and best estimates about current and new pathologist efforts. Most pathologists' efforts focus on anatomic (52%), laboratory (14%), and other direct services (8%) for individual patients. Population-focused services (12%) (eg, laboratory medical direction) and other professional responsibilities (14%) (eg, teaching, research, and hospital committees) consume the rest of their time. Modeling scenarios were used to assess the need to increase or decrease efforts related globally to the Affordable Care Act, and specifically, to genomic medicine, laboratory consolidation, laboratory medical direction, and new areas where pathologists' expertise can add value. Our modeling tool allows pathologists, educators, and policy experts to assess how various factors may affect demand for pathologists' services. These factors include an aging population, advances in biomedical technology, and changing roles in capitated, value-based, and team-based medical care systems. In the future, pathologists will likely have to assume new roles, develop new expertise, and become more efficient in practicing medicine to accommodate new value-based delivery models.

Tandem Cylinder Noise Predictions

NASA Technical Reports Server (NTRS)

Lockard, David P.; Khorrami, Mehdi R.; CHoudhari, Meelan M.; Hutcheson, Florence V.; Brooks, Thomas F.; Stead, Daniel J.

2007-01-01

In an effort to better understand landing-gear noise sources, we have been examining a simplified configuration that still maintains some of the salient features of landing-gear flow fields. In particular, tandem cylinders have been studied because they model a variety of component level interactions. The present effort is directed at the case of two identical cylinders spatially separated in the streamwise direction by 3.7 diameters. Experimental measurements from the Basic Aerodynamic Research Tunnel (BART) and Quiet Flow Facility (QFF) at NASA Langley Research Center (LaRC) have provided steady surface pressures, detailed off-surface measurements of the flow field using Particle Image Velocimetry (PIV), hot-wire measurements in the wake of the rear cylinder, unsteady surface pressure data, and the radiated noise. The experiments were conducted at a Reynolds number of 166 105 based on the cylinder diameter. A trip was used on the upstream cylinder to insure a fully turbulent shedding process and simulate the effects of a high Reynolds number flow. The parallel computational effort uses the three-dimensional Navier-Stokes solver CFL3D with a hybrid, zonal turbulence model that turns off the turbulence production term everywhere except in a narrow ring surrounding solid surfaces. The current calculations further explore the influence of the grid resolution and spanwise extent on the flow and associated radiated noise. Extensive comparisons with the experimental data are used to assess the ability of the computations to simulate the details of the flow. The results show that the pressure fluctuations on the upstream cylinder, caused by vortex shedding, are smaller than those generated on the downstream cylinder by wake interaction. Consequently, the downstream cylinder dominates the noise radiation, producing an overall directivity pattern that is similar to that of an isolated cylinder. Only calculations based on the full length of the model span were able to capture the complete decay in the spanwise correlation, thereby producing reasonable noise radiation levels.

Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology.

PubMed

Salamone, John D; Yohn, Samantha E; López-Cruz, Laura; San Miguel, Noemí; Correa, Mercè

2016-05-01

Motivation has been defined as the process that allows organisms to regulate their internal and external environment, and control the probability, proximity and availability of stimuli. As such, motivation is a complex process that is critical for survival, which involves multiple behavioural functions mediated by a number of interacting neural circuits. Classical theories of motivation suggest that there are both directional and activational aspects of motivation, and activational aspects (i.e. speed and vigour of both the instigation and persistence of behaviour) are critical for enabling organisms to overcome work-related obstacles or constraints that separate them from significant stimuli. The present review discusses the role of brain dopamine and related circuits in behavioural activation, exertion of effort in instrumental behaviour, and effort-related decision-making, based upon both animal and human studies. Impairments in behavioural activation and effort-related aspects of motivation are associated with psychiatric symptoms such as anergia, fatigue, lassitude and psychomotor retardation, which cross multiple pathologies, including depression, schizophrenia, and Parkinson's disease. Therefore, this review also attempts to provide an interdisciplinary approach that integrates findings from basic behavioural neuroscience, behavioural economics, clinical neuropsychology, psychiatry, and neurology, to provide a coherent framework for future research and theory in this critical field. Although dopamine systems are a critical part of the brain circuitry regulating behavioural activation, exertion of effort, and effort-related decision-making, mesolimbic dopamine is only one part of a distributed circuitry that includes multiple neurotransmitters and brain areas. Overall, there is a striking similarity between the brain areas involved in behavioural activation and effort-related processes in rodents and in humans. Animal models of effort-related decision-making are highly translatable to humans, and an emerging body of evidence indicates that alterations in effort-based decision-making are evident in several psychiatric and neurological disorders. People with major depression, schizophrenia, and Parkinson's disease show evidence of decision-making biases towards a lower exertion of effort. Translational studies linking research with animal models, human volunteers, and clinical populations are greatly expanding our knowledge about the neural basis of effort-related motivational dysfunction, and it is hoped that this research will ultimately lead to improved treatment for motivational and psychomotor symptoms in psychiatry and neurology. © The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Non-Hermitian physics and PT symmetry

NASA Astrophysics Data System (ADS)

El-Ganainy, Ramy; Makris, Konstantinos G.; Khajavikhan, Mercedeh; Musslimani, Ziad H.; Rotter, Stefan; Christodoulides, Demetrios N.

2018-01-01

In recent years, notions drawn from non-Hermitian physics and parity-time (PT) symmetry have attracted considerable attention. In particular, the realization that the interplay between gain and loss can lead to entirely new and unexpected features has initiated an intense research effort to explore non-Hermitian systems both theoretically and experimentally. Here we review recent progress in this emerging field, and provide an outlook to future directions and developments.

Review and Appraisal of the Federal Investment in STEM Education Research

DTIC Science & Technology

2006-10-06

science literacy and education efforts, the NIH has also been supporting the Science Education Partnership Awards (SEPA) for close to 15 years...agency websites. While individual projects may be required to work directly and closely with practitioners, rarely do federal programs convey the...understanding of the factors that give rise to this national problem and provide evidence-based corrective actions for effectively modifying the current

Promising Directions in School-Based Systems Level Consultation: A Commentary on "Has Consultation Achieved Its Primary Prevention Potential?," an Article by Joseph E. Zins

ERIC Educational Resources Information Center

Hojnoski, Robin L.

2007-01-01

From his review of research on consultation, Zins (1995) concluded (a) that a paradigm shift to a more prevention-oriented approach was necessary; (b) that systems-level consultation held significant potential; and (c) that systems-level consultation had the most data to support its use in preventive efforts. This commentary reviews promising…

High School Predictors of College Readiness: Determinants of High School Graduates' Enrollment and Successful Completion of First-Year Mathematics and English College Courses in Virginia

ERIC Educational Resources Information Center

Jonas, Deborah; Dougherty, Chrys; Herrera, Angelica Ware; LaTurner, Jason; Garland, Marshall; Ware, Anne

2012-01-01

In 2007, the Virginia Board of Education directed the Virginia Department of Education (VDOE) to study academic indicators that are associated with high school students' successful preparation for college and careers. VDOE then embarked on a multi-year effort to identify available data sources and conduct research on high school indicators that…

Understanding GPU Power. A Survey of Profiling, Modeling, and Simulation Methods

DOE PAGES

Bridges, Robert A.; Imam, Neena; Mintz, Tiffany M.

2016-09-01

Modern graphics processing units (GPUs) have complex architectures that admit exceptional performance and energy efficiency for high throughput applications.Though GPUs consume large amounts of power, their use for high throughput applications facilitate state-of-the-art energy efficiency and performance. Consequently, continued development relies on understanding their power consumption. Our work is a survey of GPU power modeling and profiling methods with increased detail on noteworthy efforts. Moreover, as direct measurement of GPU power is necessary for model evaluation and parameter initiation, internal and external power sensors are discussed. Hardware counters, which are low-level tallies of hardware events, share strong correlation to powermore » use and performance. Statistical correlation between power and performance counters has yielded worthwhile GPU power models, yet the complexity inherent to GPU architectures presents new hurdles for power modeling. Developments and challenges of counter-based GPU power modeling is discussed. Often building on the counter-based models, research efforts for GPU power simulation, which make power predictions from input code and hardware knowledge, provide opportunities for optimization in programming or architectural design. Noteworthy strides in power simulations for GPUs are included along with their performance or functional simulator counterparts when appropriate. Lastly, possible directions for future research are discussed.« less

INFORMAS (International Network for Food and Obesity/non-communicable diseases Research, Monitoring and Action Support): summary and future directions.

PubMed

Kumanyika, S

2013-10-01

This supplement presents the foundational elements for INFORMAS (International Network for Food and Obesity/non-communicable diseases Research, Monitoring and Action Support). As explained in the overview article by Swinburn and colleagues, INFORMAS has a compelling rationale and has set forth clear objectives, outcomes, principles and frameworks for monitoring and benchmarking key aspects of food environments and the policies and actions that influence the healthiness of food environments. This summary highlights the proposed monitoring approaches for the 10 interrelated INFORMAS modules: public and private sector policies and actions; key aspects of food environments (food composition, labelling, promotion, provision, retail, prices, and trade and investment) and population outcomes (diet quality). This ambitious effort should be feasible when approached in a step-wise manner, taking into account existing monitoring efforts, data sources, country contexts and capacity, and when adequately resourced. After protocol development and pilot testing of the modules, INFORMAS aims to be a sustainable, low-cost monitoring framework. Future directions relate to institutionalization, implementation and, ultimately, to leveraging INFORMAS data in ways that will bring key drivers of food environments into alignment with public health goals. © 2013 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of the International Association for the Study of Obesity.

Understanding GPU Power. A Survey of Profiling, Modeling, and Simulation Methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bridges, Robert A.; Imam, Neena; Mintz, Tiffany M.

Modern graphics processing units (GPUs) have complex architectures that admit exceptional performance and energy efficiency for high throughput applications.Though GPUs consume large amounts of power, their use for high throughput applications facilitate state-of-the-art energy efficiency and performance. Consequently, continued development relies on understanding their power consumption. Our work is a survey of GPU power modeling and profiling methods with increased detail on noteworthy efforts. Moreover, as direct measurement of GPU power is necessary for model evaluation and parameter initiation, internal and external power sensors are discussed. Hardware counters, which are low-level tallies of hardware events, share strong correlation to powermore » use and performance. Statistical correlation between power and performance counters has yielded worthwhile GPU power models, yet the complexity inherent to GPU architectures presents new hurdles for power modeling. Developments and challenges of counter-based GPU power modeling is discussed. Often building on the counter-based models, research efforts for GPU power simulation, which make power predictions from input code and hardware knowledge, provide opportunities for optimization in programming or architectural design. Noteworthy strides in power simulations for GPUs are included along with their performance or functional simulator counterparts when appropriate. Lastly, possible directions for future research are discussed.« less

New Directions in Biotechnology

NASA Technical Reports Server (NTRS)

2003-01-01

The macromolecule crystallization program within NASA is undergoing considerable pressure, particularly budgetary pressure. While it has shown some successes, they have not lived up to the expectations of others, and technological advances may rapidly overtake the natural advantages offered by crystallization in microgravity. Concomitant with the microgravity effort has been a research program to study the macromolecule crystallization process. It was believed that a better understanding of the process would lead to growth of improved crystals for X-ray diffraction studies. The results of the various research efforts have been impressive in improving our understanding of macromolecule crystallization, but have not led to any improved structures. Macromolecule crystallization for structure determination is "one of", the job being unique for every protein and finished once a structure is obtained. However, the knowledge gained is not lost, but instead lays the foundation for developments in new areas of biotechnology and nanotechnology. In this it is highly analogous to studies into small molecule crystallization, the results of which have led to our present day microelectronics-based society. We are conducting preliminary experiments into areas such as designed macromolecule crystals, macromolecule-inorganic hybrid structures, and macromolecule-based nanotechnology. In addition, our protein crystallization studies are now being directed more towards industrial and new approaches to membrane protein crystallization.

Libraries and Librarians: Key Partners for Progress in Health Literacy Research and Practice.

PubMed

Whitney, Wanda; Keselman, Alla; Humphreys, Betsy

2017-01-01

The field of librarianship has a history of involvement in patient education, general literacy and information literacy efforts. This history and prominent placement in communities make libraries and librarians an excellent resource in advancing health literacy practice and research. This chapter provides an overview of health literacy and health information literacy efforts in US libraries over the past two decades. The chapter begins with the description of the role of the US National Library of Medicine in developing resources, programs, and partnerships serving health information needs of the public. It then overviews special training programs for increasing librarians' expertise with health information and health literacy support. The narrative also presents different models of health information outreach programs in diverse communities, focusing on serving special populations that may suffer from health disparities. The second half of the chapter describes libraries' and librarians' health information response to continuously evolving contexts, mediums, and requirements. One subsection describes librarians' outreach effort with cutting-edge technologies, such as virtual worlds and gaming. Another focuses on supporting patients' information needs in clinical settings. Two more describe how libraries meet patrons' health information needs in the context of disaster preparedness and health insurance market place sign-up. While presenting the information, to the extent possible, the chapter draws upon research and evaluation of the effectiveness of different types of programs. It also discusses enablers of successes, limitations of the existing data, and directions for future research.

Libraries and Librarians: Key Partners for Progress in Health Literacy Research and Practice

PubMed Central

WHITNEY, Wanda; KESELMAN, Alla; HUMPHREYS, Betsy

2017-01-01

The field of librarianship has a history of involvement in patient education, general literacy and information literacy efforts. This history and prominent placement in communities make libraries and librarians an excellent resource in advancing health literacy practice and research. This chapter provides an overview of health literacy and health information literacy efforts in US libraries over the past two decades. The chapter begins with the description of the role of the US National Library of Medicine in developing resources, programs, and partnerships serving health information needs of the public. It then overviews special training programs for increasing librarians’ expertise with health information and health literacy support. The narrative also presents different models of health information outreach programs in diverse communities, focusing on serving special populations that may suffer from health disparities. The second half of the chapter describes libraries’ and librarians’ health information response to continuously evolving contexts, mediums, and requirements. One subsection describes librarians’ outreach effort with cutting-edge technologies, such as virtual worlds and gaming. Another focuses on supporting patients’ information needs in clinical settings. Two more describe how libraries meet patrons’ health information needs in the context of disaster preparedness and health insurance market place sign-up. While presenting the information, to the extent possible, the chapter draws upon research and evaluation of the effectiveness of different types of programs. It also discusses enablers of successes, limitations of the existing data, and directions for future research. PMID:28972531

Discovery and progress of direct cardiac reprogramming.

PubMed

Kojima, Hidenori; Ieda, Masaki

2017-06-01

Cardiac disease remains a major cause of death worldwide. Direct cardiac reprogramming has emerged as a promising approach for cardiac regenerative therapy. After the discovery of MyoD, a master regulator for skeletal muscle, other single cardiac reprogramming factors (master regulators) have been sought. Discovery of cardiac reprogramming factors was inspired by the finding that multiple, but not single, transcription factors were needed to generate induced pluripotent stem cells (iPSCs) from fibroblasts. We first reported a combination of cardiac-specific transcription factors, Gata4, Mef2c, and Tbx5 (GMT), that could convert mouse fibroblasts into cardiomyocyte-like cells, which were designated as induced cardiomyocyte-like cells (iCMs). Following our first report of cardiac reprogramming, many researchers, including ourselves, demonstrated an improvement in cardiac reprogramming efficiency, in vivo direct cardiac reprogramming for heart regeneration, and cardiac reprogramming in human cells. However, cardiac reprogramming in human cells and adult fibroblasts remains inefficient, and further efforts are needed. We believe that future research elucidating epigenetic barriers and molecular mechanisms of direct cardiac reprogramming will improve the reprogramming efficiency, and that this new technology has great potential for clinical applications.

NASA and Superalloys: A Customer, a Participant, and a Referee

NASA Technical Reports Server (NTRS)

Nathal, Michael V.

2008-01-01

NASA has had a long history of research and development in the field of superalloys. These efforts have continued today, where the latest advancements in turbine disk and blade technologies are being developed Although NASA does support military flight systems, it s predominant role is in supporting civilian air transportation systems, and thus has goals for improving fuel efficiency, emissions, noise, and safety of today s aircraft. NASA has traditionally served several distinct but complimentary roles as participants in multi-disciplinary research teams, as customers who fund research and development efforts at industry and universities, and as referees who can address broad issues that affect the entire aeronautics community. Because of our longer range viewpoint, we can take on higher risk, higher reward research topics. NASA can also serve as an intermediary between the basic research performed primarily at universities and the development efforts emphasized by industry. By interacting with individual companies, NASA can identify areas of general interest and problems common to a large portion of the aeronautics community, and devise programs aimed at solving these problems. In space missions, NASA is a direct customer responsible for developing vehicles. In the case of the Space Shuttle, NASA has worked with various contractors to design and build numerous components out of superalloys. Another fascinating area for the use of superalloys is in power systems for long life applications in space. Potential missions include providing electric power for deep space missions, surface rovers, including lunar and Mars, and stationary power generators on the lunar surface.

A Research Agenda for Malaria Eradication: Vaccines

PubMed Central

2011-01-01

Vaccines could be a crucial component of efforts to eradicate malaria. Current attempts to develop malaria vaccines are primarily focused on Plasmodium falciparum and are directed towards reducing morbidity and mortality. Continued support for these efforts is essential, but if malaria vaccines are to be used as part of a repertoire of tools for elimination or eradication of malaria, they will need to have an impact on malaria transmission. We introduce the concept of “vaccines that interrupt malaria transmission” (VIMT), which includes not only “classical” transmission-blocking vaccines that target the sexual and mosquito stages but also pre-erythrocytic and asexual stage vaccines that have an effect on transmission. VIMT may also include vaccines that target the vector to disrupt parasite development in the mosquito. Importantly, if eradication is to be achieved, malaria vaccine development efforts will need to target other malaria parasite species, especially Plasmodium vivax, where novel therapeutic vaccines against hypnozoites or preventive vaccines with effect against multiple stages could have enormous impact. A target product profile (TPP) for VIMT is proposed and a research agenda to address current knowledge gaps and develop tools necessary for design and development of VIMT is presented. PMID:21311586

A research agenda for malaria eradication: vaccines.

PubMed

2011-01-25

Vaccines could be a crucial component of efforts to eradicate malaria. Current attempts to develop malaria vaccines are primarily focused on Plasmodium falciparum and are directed towards reducing morbidity and mortality. Continued support for these efforts is essential, but if malaria vaccines are to be used as part of a repertoire of tools for elimination or eradication of malaria, they will need to have an impact on malaria transmission. We introduce the concept of "vaccines that interrupt malaria transmission" (VIMT), which includes not only "classical" transmission-blocking vaccines that target the sexual and mosquito stages but also pre-erythrocytic and asexual stage vaccines that have an effect on transmission. VIMT may also include vaccines that target the vector to disrupt parasite development in the mosquito. Importantly, if eradication is to be achieved, malaria vaccine development efforts will need to target other malaria parasite species, especially Plasmodium vivax, where novel therapeutic vaccines against hypnozoites or preventive vaccines with effect against multiple stages could have enormous impact. A target product profile (TPP) for VIMT is proposed and a research agenda to address current knowledge gaps and develop tools necessary for design and development of VIMT is presented.

The three-dimensional structures of bacterial reaction centers.

PubMed

Olson, T L; Williams, J C; Allen, J P

2014-05-01

This review presents a broad overview of the research that enabled the structure determination of the bacterial reaction centers from Blastochloris viridis and Rhodobacter sphaeroides, with a focus on the contributions from Duysens, Clayton, and Feher. Early experiments performed in the laboratory of Duysens and others demonstrated the utility of spectroscopic techniques and the presence of photosynthetic complexes in both oxygenic and anoxygenic photosynthesis. The laboratories of Clayton and Feher led efforts to isolate and characterize the bacterial reaction centers. The availability of well-characterized preparations of pure and stable reaction centers allowed the crystallization and subsequent determination of the structures using X-ray diffraction. The three-dimensional structures of reaction centers revealed an overall arrangement of two symmetrical branches of cofactors surrounded by transmembrane helices from the L and M subunits, which also are related by the same twofold symmetry axis. The structure has served as a framework to address several issues concerning bacterial photosynthesis, including the directionality of electron transfer, the properties of the reaction center-cytochrome c 2 complex, and the coupling of proton and electron transfer. Together, these research efforts laid the foundation for ongoing efforts to address an outstanding question in oxygenic photosynthesis, namely the molecular mechanism of water oxidation.

In the eye of the beholder: eye contact increases resistance to persuasion.

PubMed

Chen, Frances S; Minson, Julia A; Schöne, Maren; Heinrichs, Markus

2013-11-01

Popular belief holds that eye contact increases the success of persuasive communication, and prior research suggests that speakers who direct their gaze more toward their listeners are perceived as more persuasive. In contrast, we demonstrate that more eye contact between the listener and speaker during persuasive communication predicts less attitude change in the direction advocated. In Study 1, participants freely watched videos of speakers expressing various views on controversial sociopolitical issues. Greater direct gaze at the speaker's eyes was associated with less attitude change in the direction advocated by the speaker. In Study 2, we instructed participants to look at either the eyes or the mouths of speakers presenting arguments counter to participants' own attitudes. Intentionally maintaining direct eye contact led to less persuasion than did gazing at the mouth. These findings suggest that efforts at increasing eye contact may be counterproductive across a variety of persuasion contexts.

Future Directions for Research in Autism Spectrum Disorders

PubMed Central

Damiano, Cara R.; Mazefsky, Carla A.; White, Susan W.; Dichter, Gabriel S.

2014-01-01

This article suggests future directions for research aimed at improved understanding of the etiology and pathophysiology of autism spectrum disorder (ASD) as well as pharmacologic and psychosocial interventions for ASD across the lifespan. The past few years have witnessed unprecedented transformations in the understanding of ASD neurobiology, genetics, early identification, and early intervention. However, recent increases in ASD prevalence estimates highlight the urgent need for continued efforts to translate novel ASD discoveries into effective interventions for all individuals with ASD. In this article we highlight promising areas for ongoing and new research expected to quicken the pace of scientific discovery and ultimately the translation of research findings into accessible and empirically supported interventions for those with ASD. We highlight emerging research in the following domains as particularly promising and pressing: (1) preclinical models; (2) experimental therapeutics; (3) early identification and intervention; (4) psychiatric comorbidities and the Research Domain Criteria (RDoC) initiative; (5) ecological momentary assessment; (6) neurotechnologies; and (7) the needs of adults with ASD. Increased research emphasis in these areas has the potential to hasten the translation of knowledge on the etiological mechanisms of ASD to psychosocial and biological interventions to reduce the burden of ASD on affected individuals and their families. PMID:25216048

Moving from Petroleum to Plants to Energize our World (A "Life at the Frontiers of Energy Research" contest entry from the 2011 Energy Frontier Research Centers (EFRCs) Summit and Forum)

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCann, Maureen; Yohe, Sara

"Moving from Petroleum to Plants to Energize our World" was submitted by the Center for Direct Catalytic Conversion of Biomass to Biofuels (C3Bio) to the "Life at the Frontiers of Energy Research" video contest at the 2011 Science for Our Nation's Energy Future: Energy Frontier Research Centers (EFRCs) Summit and Forum. Twenty-six EFRCs created short videos to highlight their mission and their work. C3Bio, an EFRC directed by Maureen McCann at Purdue University is a partnership between five institutions: Purdue (lead), National Renewable Energy Laboratory, Northeastern University, University of California Santa Barbara and the University of Tennessee. The Office ofmore » Basic Energy Sciences in the U.S. Department of Energy's Office of Science established the 46 Energy Frontier Research Centers (EFRCs) in 2009. These collaboratively-organized centers conduct fundamental research focused on 'grand challenges' and use-inspired 'basic research needs' recently identified in major strategic planning efforts by the scientific community. The overall purpose is to accelerate scientific progress toward meeting the nation's critical energy challenges.« less

Moving from Petroleum to Plants to Energize our World (A "Life at the Frontiers of Energy Research" contest entry from the 2011 Energy Frontier Research Centers (EFRCs) Summit and Forum)

ScienceCinema

McCann, Maureen (Director, Center for Direct Catalytic Conversion of Biomass to Biofuels); C3Bio Staff

2017-12-09

'Moving from Petroleum to Plants to Energize our World' was submitted by the Center for Direct Catalytic Conversion of Biomass to Biofuels (C3Bio) to the 'Life at the Frontiers of Energy Research' video contest at the 2011 Science for Our Nation's Energy Future: Energy Frontier Research Centers (EFRCs) Summit and Forum. Twenty-six EFRCs created short videos to highlight their mission and their work. C3Bio, an EFRC directed by Maureen McCann at Purdue University is a partnership between five institutions: Purdue (lead), Argonne National Laboratory, National Renewable Energy Laboratory, Northeastern University, and the University of Tennessee. The Office of Basic Energy Sciences in the U.S. Department of Energy's Office of Science established the 46 Energy Frontier Research Centers (EFRCs) in 2009. These collaboratively-organized centers conduct fundamental research focused on 'grand challenges' and use-inspired 'basic research needs' recently identified in major strategic planning efforts by the scientific community. The overall purpose is to accelerate scientific progress toward meeting the nation's critical energy challenges.

Healthy sex and sexual health: new directions for studying outcomes of sexual health.

PubMed

Lefkowitz, Eva S; Vasilenko, Sara A

2014-01-01

Sexual behavior is an important aspect of adolescent development with implications for well-being. These chapters highlight important perspectives on studying sexual health from a normative, developmental perspective, such as viewing a range of sexual behaviors as life events; considering potentially positive physical health, mental health, social health, and identity outcomes; examining both intraindividual and interindividual differences in outcomes; recognizing the romantic relationship context of sexual behavior; and understanding how sexual media may impact sexual health outcomes. We suggest new directions for studying sexual health outcomes, such as studying behaviors beyond vaginal sex and condom use, new methodologies such as latent class analysis, sophisticated longitudinal designs, and collection and analysis of dyadic data. We recommend research on populations underrepresented in sexual health research such as late adolescents who do not attend traditional universities and adolescents from ethnic/racial minorities. Finally, we consider future directions for sexuality education and prevention efforts. © 2014 Wiley Periodicals, Inc.

Complementary Strategies for Directed C(sp3 )-H Functionalization: A Comparison of Transition-Metal-Catalyzed Activation, Hydrogen Atom Transfer, and Carbene/Nitrene Transfer.

PubMed

Chu, John C K; Rovis, Tomislav

2018-01-02

The functionalization of C(sp 3 )-H bonds streamlines chemical synthesis by allowing the use of simple molecules and providing novel synthetic disconnections. Intensive recent efforts in the development of new reactions based on C-H functionalization have led to its wider adoption across a range of research areas. This Review discusses the strengths and weaknesses of three main approaches: transition-metal-catalyzed C-H activation, 1,n-hydrogen atom transfer, and transition-metal-catalyzed carbene/nitrene transfer, for the directed functionalization of unactivated C(sp 3 )-H bonds. For each strategy, the scope, the reactivity of different C-H bonds, the position of the reacting C-H bonds relative to the directing group, and stereochemical outcomes are illustrated with examples in the literature. The aim of this Review is to provide guidance for the use of C-H functionalization reactions and inspire future research in this area. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Direct-to-consumer marketing of evidence-based psychological interventions: introduction.

PubMed

Santucci, Lauren C; McHugh, R Kathryn; Barlow, David H

2012-06-01

The dissemination and implementation of evidence-based psychological interventions (EBPIs) to service provision settings has been a major challenge. Most efforts to disseminate and implement EBPIs have focused on clinicians and clinical systems as the consumers of these treatments and thus have targeted efforts to these groups. An alternative, complementary approach to achieve more widespread utilization of EBPIs is to disseminate directly to patients themselves. The aim of this special section is to explore several direct-to-consumer (i.e., patient) dissemination and education efforts currently underway. This manuscript highlights the rationale for direct-to-patient dissemination strategies as well as the application of marketing science to dissemination efforts. Achieving greater access to EBPIs will require the use of multiple approaches to overcome the many and varied barriers to successful dissemination and implementation. Copyright © 2011. Published by Elsevier Ltd.

Monitoring and control technologies for bioregenerative life support systems/CELSS

NASA Technical Reports Server (NTRS)

Knott, William M.; Sager, John C.

1991-01-01

The development of a controlled Ecological Life Support System (CELSS) will require NASA to develop innovative monitoring and control technologies to operate the different components of the system. Primary effort over the past three to four years has been directed toward the development of technologies to operate a biomass production module. Computer hardware and software required to operate, collect, and summarize environmental data for a large plant growth chamber facility were developed and refined. Sensors and controls required to collect information on such physical parameters as relative humidity, temperature, irradiance, pressure, and gases in the atmosphere; and PH, dissolved oxygen, fluid flow rates, and electrical conductivity in the nutrient solutions are being developed and tested. Technologies required to produce high artificial irradiance for plant growth and those required to collect and transport natural light into a plant growth chamber are also being evaluated. Significant effort was directed towards the development and testing of a membrane nutrient delivery system required to manipulate, seed, and harvest crops, and to determine plant health prior to stress impacting plant productivity are also being researched. Tissue culture technologies are being developed for use in management and propagation of crop plants. Though previous efforts have focussed on development of technologies required to operate a biomass production module for a CELSS, current efforts are expanding to include technologies required to operate modules such as food preparation, biomass processing, and resource (waste) recovery which are integral parts of the CELSS.

Delivering vaccines to the people who need them most

PubMed Central

Barocchi, Michèle Anne; Rappuoli, Rino

2015-01-01

Thanks to the Global Alliance for Vaccines and Immunization (GAVI), the Vaccine Fund and the Bill & Melinda Gates Foundation, the global health community has made enormous progress in providing already existing vaccines to developing countries. However, there still exists a gap to develop vaccines for which there is no market in the Western world, owing to low economic incentives for the private sector to justify the investments necessary for vaccine development. In many cases, industry has the technologies, but lacks the impetus to direct resources to develop these vaccine products. The present emergency with the Ebola vaccine provides us an excellent example where a vaccine was feasible several years ago, but the global health community waited for a humanitarian disaster to direct efforts and resources to develop this vaccine. In the beginning of 2015, the first large-scale trials of two experimental vaccines against Ebola virus disease have begun in West Africa. During the past few years, several institutions have dedicated efforts to the development of vaccines against diseases present only in low-income countries. These include the International Vaccine Institute, the Novartis Vaccines Institute for Global Health, the Hilleman Institute, the Sabin Vaccine Institute and the Infectious Disease Research Institute. Nevertheless, solving this problem requires a more significant global effort than that currently invested. These efforts include a clear policy, global coordination of funds dedicated to the development of neglected disease and an agreement on regulatory strategies and incentives for the private sector. PMID:25964460

The Component Packaging Problem: A Vehicle for the Development of Multidisciplinary Design and Analysis Methodologies

NASA Technical Reports Server (NTRS)

Fadel, Georges; Bridgewood, Michael; Figliola, Richard; Greenstein, Joel; Kostreva, Michael; Nowaczyk, Ronald; Stevenson, Steve

1999-01-01

This report summarizes academic research which has resulted in an increased appreciation for multidisciplinary efforts among our students, colleagues and administrators. It has also generated a number of research ideas that emerged from the interaction between disciplines. Overall, 17 undergraduate students and 16 graduate students benefited directly from the NASA grant: an additional 11 graduate students were impacted and participated without financial support from NASA. The work resulted in 16 theses (with 7 to be completed in the near future), 67 papers or reports mostly published in 8 journals and/or presented at various conferences (a total of 83 papers, presentations and reports published based on NASA inspired or supported work). In addition, the faculty and students presented related work at many meetings, and continuing work has been proposed to NSF, the Army, Industry and other state and federal institutions to continue efforts in the direction of multidisciplinary and recently multi-objective design and analysis. The specific problem addressed is component packing which was solved as a multi-objective problem using iterative genetic algorithms and decomposition. Further testing and refinement of the methodology developed is presently under investigation. Teaming issues research and classes resulted in the publication of a web site, (http://design.eng.clemson.edu/psych4991) which provides pointers and techniques to interested parties. Specific advantages of using iterative genetic algorithms, hurdles faced and resolved, and institutional difficulties associated with multi-discipline teaming are described in some detail.

Report Summarizing the Effort Required to Initiate Welding of Irradiated Materials within the Welding Cubicle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frederick, Greg; Sutton, Benjamin J.; Tatman, Jonathan K.

The advanced welding facility within a hot cell at the Radiochemical Engineering Development Center of Oak Ridge National Laboratory (ORNL), which has been jointly funded by the U.S. Department of Energy (DOE), Office of Nuclear Energy, Light Water Reactor Sustainability Program and the Electric Power Research Institute, Long Term Operations Program and the Welding and Repair Technology Center, is in the final phase of development. Research and development activities in this facility will involve direct testing of advanced welding technologies on irradiated materials in order to address the primary technical challenge of helium induced cracking that can arise when conventionalmore » fusion welding techniques are utilized on neutron irradiated stainless steels and nickel-base alloys. This report details the effort that has been required since the beginning of fiscal year 2017 to initiate welding research and development activities on irradiated materials within the hot cell cubicle, which houses welding sub-systems that include laser beam welding (LBW) and friction stir welding (FSW) and provides material containment within the hot cell.« less

NASA Goddard Thermal Technology Overview 2018

NASA Technical Reports Server (NTRS)

Butler, Dan; Swanson, Ted

2018-01-01

This presentation summarizes the current plans and efforts at NASA/Goddard to develop new thermal control technology for anticipated future missions. It will also address some of the programmatic developments currently underway at NASA, especially with respect to the NASA Technology Development Program. The effects of the recently submitted NASA budget will also be addressed. While funding for basic technology development is still tight, significant efforts are being made in direct support of flight programs. Thermal technology Implementation on current flight programs will be reviewed, and the recent push for Cube-sat mission development will also be addressed. Many of these technologies also have broad applicability to DOD, DOE, and commercial programs. Partnerships have been developed with the Air Force, Navy, and various universities to promote technology development. In addition, technology development activities supported by internal research and development (IRAD) program and the Small Business Innovative Research (SBIR) program are reviewed in this presentation. Specific technologies addressed include; two-phase systems applications and issues on NASA missions, latest developments of thermal control coatings, Atomic Layer Deposition (ALD), Micro-scale Heat Transfer, and various other research activities.

App Factory: A flexible approach to rehabilitation engineering in an era of rapid technology advancement.

PubMed

Jones, Michael; Mueller, James; Morris, John

2017-01-01

This article describes a flexible and effective approach to research and development in an era of rapid technological advancement. The approach relies on secondary dispersal of grant funds to commercial developers through a competitive selection process. This "App Factory" model balances the practical reliance on multi-year funding needed to sustain a rehabilitation engineering research center (RERC), with the need for agility and adaptability of development efforts undertaken in a rapidly changing technology environment. This approach also allows us to take advantage of technical expertise needed to accomplish a particular development task, and provides incentives to deliver successful products in a cost-effective manner. In this article, we describe the App Factory structure, process, and results achieved to date; and we discuss the lessons learned and the potential relevance of this approach for other grant-funded research and development efforts. Data presented on the direct costs and number of downloads of the 16 app development projects funded in the App Factory's first 3 years show that it can be an effective means for supporting focused, short-term assistive technology development projects.

Marginalization of end-use technologies in energy innovation for climate protection

NASA Astrophysics Data System (ADS)

Wilson, Charlie; Grubler, Arnulf; Gallagher, Kelly S.; Nemet, Gregory F.

2012-11-01

Mitigating climate change requires directed innovation efforts to develop and deploy energy technologies. Innovation activities are directed towards the outcome of climate protection by public institutions, policies and resources that in turn shape market behaviour. We analyse diverse indicators of activity throughout the innovation system to assess these efforts. We find efficient end-use technologies contribute large potential emission reductions and provide higher social returns on investment than energy-supply technologies. Yet public institutions, policies and financial resources pervasively privilege energy-supply technologies. Directed innovation efforts are strikingly misaligned with the needs of an emissions-constrained world. Significantly greater effort is needed to develop the full potential of efficient end-use technologies.

An integrated approach to the optimum design of actively controlled composite wings

NASA Technical Reports Server (NTRS)

Livne, E.

1989-01-01

The importance of interactions among the various disciplines in airplane wing design has been recognized for quite some time. With the introduction of high gain, high authority control systems and the design of thin, flexible, lightweight composite wings, the integrated treatment of control systems, flight mechanics and dynamic aeroelasticity became a necessity. A research program is underway now aimed at extending structural synthesis concepts and methods to the integrated synthesis of lifting surfaces, spanning the disciplines of structures, aerodynamics and control for both analysis and design. Mathematical modeling techniques are carefully selected to be accurate enough for preliminary design purposes of the complicated, built-up lifting surfaces of real aircraft with their multiple design criteria and tight constraints. The presentation opens with some observations on the multidisciplinary nature of wing design. A brief review of some available state of the art practical wing optimization programs and a brief review of current research effort in the field serve to illuminate the motivation and support the direction taken in our research. The goals of this research effort are presented, followed by a description of the analysis and behavior sensitivity techniques used. The presentation concludes with a status report and some forecast of upcoming progress.

Monitoring the tobacco use epidemic IV. The vector: Tobacco industry data sources and recommendations for research and evaluation.

PubMed

Cruz, Tess Boley

2009-01-01

This Vector paper (IV of V on monitoring the tobacco use epidemic) presents the data sources and methods that can be used to monitor tobacco marketing and makes recommendations for creating a national surveillance system. In 2002, the Vector Work Group of the National Tobacco Monitoring, Research and Evaluation Workshop identified priority indicators of tobacco marketing: tobacco brand pricing strategies, retail environment advertising and promotional allowances, gray market or smuggling activities, lobbying, direct mail marketing, tobacco brand placements in films, Internet promotions, and sponsorship at bars and events. This paper reviews and identifies data sources and gaps for these priority indicators and for 12 other indicators of interest. There are 38 commercial data sites and Internet sources, as well as individual research efforts that address the priority indicators. These sources are not integrated, often costly, and limited in standardization. Tobacco marketing could be more effectively monitored with the development of a national research network. Surveillance of the tobacco industry's methods to push tobacco and pull consumers can help the public health community identify new markets and campaigns, justify and tailor effective tobacco control strategies, and evaluate existing counter-marketing efforts.

EFRC: Polymer-Based Materials for Harvesting Solar Energy (stimulus)"

DOE Office of Scientific and Technical Information (OSTI.GOV)

Russell, Thomas P.

The University of Massachusetts Amherst is proposing an Energy Frontier Research Center (EFRC) on Polymer-Based Materials for Harvesting Solar Energy that will integrate the widely complementary experimental and theoretical expertise of 23 faculty at UMass-Amherst Departments with researchers from the University of Massachusetts Lowell, University of Pittsburgh, the Pennsylvania State University and Konarka Technologies, Inc. Collaborative efforts with researchers at the Oak Ridge National Laboratory, the University of Bayreuth, Seoul National University and Tohoku University will complement and expand the experimental efforts in the EFRC. Our primary research aim of this EFRC is the development of hybrid polymer-based devices withmore » efficiencies more than twice the current organic-based devices, by combining expertise in the design and synthesis of photoactive polymers, the control and guidance of polymer-based assemblies, leadership in nanostructured polymeric materials, and the theory and modeling of non-equilibrium structures. A primary goal of this EFRC is to improve the collection and conversion efficiency of a broader spectral range of solar energy using the directed self-assembly of polymer-based materials so as to optimize the design and fabrication of inexpensive devices.« less

LDRD 2013 Annual Report: Laboratory Directed Research and Development Program Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bookless, W.

This LDRD project establishes a research program led by Jingguang Chen, who has started a new position as a Joint Appointee between BNL and Columbia University as of FY2013. Under this project, Dr. Chen will establish a new program in catalysis science at BNL and Columbia University. The LDRD program will provide initial research funding to start research at both BNL and Columbia. At BNL, Dr. Chen will initiate laboratory research, including hiring research staff, and will collaborate with the existing BNL catalysis and electrocatalysis research groups. At Columbia, a subcontract to Dr. Chen will provide startup funding for hismore » laboratory research, including initial graduate student costs. The research efforts will be linked under a common Catalysis Program in Sustainable Fuels. The overall impact of this project will be to strengthen the BNL catalysis science program through new linked research thrusts and the addition of an internationally distinguished catalysis scientist.« less

Global research coaching in orthopedic surgery: seeding for an international network

PubMed Central

Ferreira, Ana Paula Bonilauri; Rajgor, Dimple; Shah, Jatin; Shah, Anand; Pietrobon, Ricardo

2012-01-01

Despite the importance of delivering evidence-based health care, orthopedic surgeons have directed fewer efforts towards the generation of such evidence. Even when present, published evidence lacks methodological rigor and is known to be inaccurate. One of the main reasons for the lack of generation of quality evidence, and the low involvement in research among orthopedic surgeons, is the lack of structured research coaching environments where they can learn concepts and hone their research skills. There is a palpable need for a pragmatic and outcome-oriented approach that can equip orthopedic surgeons with effective ways of communicating their research in writing. We describe a pragmatic research coaching program, designed and developed by the Research on Research group, which aims to build a global network of orthopedic researchers trained in streamlined and standardized research methods. We also provide a brief overview of the course principles and tools, and the platforms used in this program. PMID:24453591

Interactions between human behaviour and ecological systems.

PubMed

Milner-Gulland, E J

2012-01-19

Research on the interactions between human behaviour and ecological systems tends to focus on the direct effects of human activities on ecosystems, such as biodiversity loss. There is also increasing research effort directed towards ecosystem services. However, interventions to control people's use of the environment alter the incentives that natural resource users face, and therefore their decisions about resource use. The indirect effects of conservation interventions on biodiversity, modulated through human decision-making, are poorly studied but are likely to be significant and potentially counterintuitive. This is particularly so where people are dependent on multiple natural resources for their livelihoods, when both poverty and biodiversity loss are acute. An inter-disciplinary approach is required to quantify these interactions, with an understanding of human decision-making at its core; otherwise, predictions about the impacts of conservation policies may be highly misleading.

Interactions between human behaviour and ecological systems

PubMed Central

Milner-Gulland, E. J.

2012-01-01

Research on the interactions between human behaviour and ecological systems tends to focus on the direct effects of human activities on ecosystems, such as biodiversity loss. There is also increasing research effort directed towards ecosystem services. However, interventions to control people's use of the environment alter the incentives that natural resource users face, and therefore their decisions about resource use. The indirect effects of conservation interventions on biodiversity, modulated through human decision-making, are poorly studied but are likely to be significant and potentially counterintuitive. This is particularly so where people are dependent on multiple natural resources for their livelihoods, when both poverty and biodiversity loss are acute. An inter-disciplinary approach is required to quantify these interactions, with an understanding of human decision-making at its core; otherwise, predictions about the impacts of conservation policies may be highly misleading. PMID:22144389

Current Status and Recent Research Achievements in SiC/SiC Composites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Katoh, Yutai; Snead, Lance L.; Henager, Charles H.

2014-12-01

The development and maturation of the silicon carbide fiber-reinforced silicon carbide matrix (SiC/SiC) composite system for fusion applications has seen the evolution from fundamental development and understanding of the material system and its behavior in a hostile irradiation environment to the current effort which essentially is a broad-based program of technology, directed at moving this material class from a laboratory curiosity to an engineering material. This paper lays out the recent international scientific and technological achievements in the development of SiC/SiC composite material technologies for fusion application and will discuss future research directions. It also reviews the materials system inmore » the larger context of progress to maturity as an engineering material for both the larger nuclear community and for general engineering applications.« less

Flight test validation of a design procedure for digital autopilots

NASA Technical Reports Server (NTRS)

Bryant, W. H.

1983-01-01

Commercially available general aviation autopilots are currently in transition from an analogue circuit system to a computer implemented digital flight control system. Well known advantages of the digital autopilot include enhanced modes, self-test capacity, fault detection, and greater computational capacity. A digital autopilot's computational capacity can be used to full advantage by increasing the sophistication of the digital autopilot's chief function, stability and control. NASA's Langley Research Center has been pursuing the development of direct digital design tools for aircraft stabilization systems for several years. This effort has most recently been directed towards the development and realization of multi-mode digital autopilots for GA aircraft, conducted under a SPIFR-related program called the General Aviation Terminal Operations Research (GATOR) Program. This presentation focuses on the implementation and testing of a candidate multi-mode autopilot designed using these newly developed tools.

Prospects and challenges for fungal metatranscriptomes of complex communities

DOE PAGES

Kuske, Cheryl Rae; Hesse, Cedar Nelson; Challacombe, Jean Faust; ...

2015-01-22

We report that the ability to extract and purify messenger RNA directly from plants, decomposing organic matter and soil, followed by high-throughput sequencing of the pool of expressed genes, has spawned the emerging research area of metatranscriptomics. Each metatranscriptome provides a snapshot of the composition and relative abundance of actively transcribed genes, and thus provides an assessment of the interactions between soil microorganisms and plants, and collective microbial metabolic processes in many environments. We highlight current approaches for analysis of fungal transcriptome and metatranscriptome datasets across a gradient of community complexity, and note benefits and pitfalls associated with those approaches.more » Finally, we discuss knowledge gaps that limit our current ability to interpret metatranscriptome datasets and suggest future research directions that will require concerted efforts within the scientific community.« less

Large-Scale 3D Printing: The Way Forward

NASA Astrophysics Data System (ADS)

Jassmi, Hamad Al; Najjar, Fady Al; Ismail Mourad, Abdel-Hamid

2018-03-01

Research on small-scale 3D printing has rapidly evolved, where numerous industrial products have been tested and successfully applied. Nonetheless, research on large-scale 3D printing, directed to large-scale applications such as construction and automotive manufacturing, yet demands a great a great deal of efforts. Large-scale 3D printing is considered an interdisciplinary topic and requires establishing a blended knowledge base from numerous research fields including structural engineering, materials science, mechatronics, software engineering, artificial intelligence and architectural engineering. This review article summarizes key topics of relevance to new research trends on large-scale 3D printing, particularly pertaining (1) technological solutions of additive construction (i.e. the 3D printers themselves), (2) materials science challenges, and (3) new design opportunities.

Developing a public health research agenda for women with blood disorders.

PubMed

Byams, Vanessa R; Beckman, Michele G; Grant, Althea M; Parker, Christopher S

2010-07-01

Bleeding and clotting in women is an issue that directly affects the life of every woman, child, and family worldwide. This article summarizes recent activities undertaken by the Division of Blood Disorders (DBD) at the Centers for Disease Control and Prevention (CDC) to identify risk factors through evidence-based research and surveillance to prevent complications of blood disorders in women. Specific focus is given to our efforts to improve early identification and diagnosis of blood disorders among women, improve our understanding of maternal and infant outcomes, and develop surveillance systems to monitor the prevalence and incidence of these events.

Research Driven Policy: Is Financial Capacity Related to Dangerousness?

PubMed

DeLeon, Patrick H; Paxton, Maegan M; Spencer, Tonya; Bajjani-Gebara, Jouhayna E

2018-05-22

Current Veterans administration policy directly links a Veteran's adjudged capacity to manage personal financial resources with their ability to purchase or possess a firearm, pursuant to the regulatory authority of the National Instant Criminal Background Check System (NICS). Preventing Veterans' suicide is a highly laudable public health objective. Effectively utilizing scientific research to "inform" public policy is equally important. The authors should be congratulated for their efforts. However, it is important in utilizing large set population-based data, especially social science data, to evaluate policy alternatives that there be substantial face (i.e., clinical) validity. Correlation does not necessarily represent causation.

Critical Problems Stalling Progress in Natural Bioactive Polysaccharide Research and Development.

PubMed

Han, Quan-Bin

2018-05-09

Natural polysaccharides are attracting increasing attention from food and pharmaceutical industries for their wide range of valuable biological activities. However, the poor repeatability of the methods used in sample preparation and chemical characterization is hampering both research and product development. The unstandardized quality, in turn, undermines efforts to understand the mechanism by which they work via oral dose, which is essential to realize the full beneficial potential of polysaccharides. Some scientists believe polysaccharides work by direct gut absorption; however, increasing evidence points to the gut microbiome and intestinal Peyer's patches as holding the keys to how they work.

Introducing meta-services for biomedical information extraction

PubMed Central

Leitner, Florian; Krallinger, Martin; Rodriguez-Penagos, Carlos; Hakenberg, Jörg; Plake, Conrad; Kuo, Cheng-Ju; Hsu, Chun-Nan; Tsai, Richard Tzong-Han; Hung, Hsi-Chuan; Lau, William W; Johnson, Calvin A; Sætre, Rune; Yoshida, Kazuhiro; Chen, Yan Hua; Kim, Sun; Shin, Soo-Yong; Zhang, Byoung-Tak; Baumgartner, William A; Hunter, Lawrence; Haddow, Barry; Matthews, Michael; Wang, Xinglong; Ruch, Patrick; Ehrler, Frédéric; Özgür, Arzucan; Erkan, Güneş; Radev, Dragomir R; Krauthammer, Michael; Luong, ThaiBinh; Hoffmann, Robert; Sander, Chris; Valencia, Alfonso

2008-01-01

We introduce the first meta-service for information extraction in molecular biology, the BioCreative MetaServer (BCMS; ). This prototype platform is a joint effort of 13 research groups and provides automatically generated annotations for PubMed/Medline abstracts. Annotation types cover gene names, gene IDs, species, and protein-protein interactions. The annotations are distributed by the meta-server in both human and machine readable formats (HTML/XML). This service is intended to be used by biomedical researchers and database annotators, and in biomedical language processing. The platform allows direct comparison, unified access, and result aggregation of the annotations. PMID:18834497

The Evolution of Neuroprosthetic Interfaces

PubMed Central

Adewole, Dayo O.; Serruya, Mijail D.; Harris, James P.; Burrell, Justin C.; Petrov, Dmitriy; Chen, H. Isaac; Wolf, John A.; Cullen, D. Kacy

2017-01-01

The ideal neuroprosthetic interface permits high-quality neural recording and stimulation of the nervous system while reliably providing clinical benefits over chronic periods. Although current technologies have made notable strides in this direction, significant improvements must be made to better achieve these design goals and satisfy clinical needs. This article provides an overview of the state of neuroprosthetic interfaces, starting with the design and placement of these interfaces before exploring the stimulation and recording platforms yielded from contemporary research. Finally, we outline emerging research trends in an effort to explore the potential next generation of neuroprosthetic interfaces. PMID:27652455

Does Pluto Have a Haze Layer?

NASA Technical Reports Server (NTRS)

Elliot, James L.

1997-01-01

The goal of this research was to determine whether Pluto has a haze layer through observations (with the Kuiper Airborne Observatory) of a stellar occultation by Pluto that was originally predicted to occur on 1993 October 3. As described in the attached material, our extensive astrometric measurements determined that this occultation would not be visible from Earth, and we canceled plans to observe it with the KAO. Efforts were then directed toward improving our astrometric techniques so that we could find future occultations with which we could satisfy the original goals of the research proposed for this grant.

Manpower Substitution and Productivity in Medical Practice

PubMed Central

Reinhardt, Uwe E.

1973-01-01

Probably in response to the often alleged physician shortage in this country, concerted research efforts are under way to identify technically feasible opportunities for manpower substitution in the production of ambulatory health care. The approaches range from descriptive studies of the effect of task delegation on output of medical services to rigorous mathematical modeling of health care production by means of linear or continuous production functions. In this article the distinct methodological approaches underlying mathematical models are presented in synopsis, and their inherent strengths and weaknesses are contrasted. The discussion includes suggestions for future research directions. Images Fig. 2 PMID:4586735

A 3D-PIV System for Gas Turbine Applications

NASA Astrophysics Data System (ADS)

Acharya, Sumanta

2002-08-01

Funds were received in April 2001 under the Department of Defense DURIP program for construction of a 48 processor high performance computing cluster. This report details the hardware, which was purchased, and how it has been used to enable and enhance research activities directly supported by, and of interest to, the Air Force Office of Scientific Research and the Department of Defense. The report is divided into two major sections. The first section after the summary describes the computer cluster, its setup, and some cluster hardware, and presents highlights of those efforts since installation of the cluster.

How Do I Find the Evidence? Find Your Librarian-Stat!

PubMed

Eresuma, Emily; Lake, Erica

Clinical nurses often struggle with a lack of time and proficiency when it comes to finding and reviewing research. Knowing where to start, and discerning which search terms will retrieve the best results, can be arduous. As expert searchers, medical librarians have the skills and knowledge to make significant contributions to the clinical team, helping nurses navigate information resources and research from start to finish. When there is not direct access to a librarian, the toolbox of resources outlined in the article can save nurses' time and effort when they require quality, evidence-based information.

Advocacy for Health Equity: A Synthesis Review

PubMed Central

Farrer, Linden; Marinetti, Claudia; Cavaco, Yoline Kuipers; Costongs, Caroline

2015-01-01

Context Health inequalities are systematic differences in health among social groups that are caused by unequal exposure to—and distributions of—the social determinants of health (SDH). They are persistent between and within countries despite action to reduce them. Advocacy is a means of promoting policies that improve health equity, but the literature on how to do so effectively is dispersed. The aim of this review is to synthesize the evidence in the academic and gray literature and to provide a body of knowledge for advocates to draw on to inform their efforts. Methods This article is a systematic review of the academic literature and a fixed-length systematic search of the gray literature. After applying our inclusion criteria, we analyzed our findings according to our predefined dimensions of advocacy for health equity. Last, we synthesized our findings and made a critical appraisal of the literature. Findings The policy world is complex, and scientific evidence is unlikely to be conclusive in making decisions. Timely qualitative, interdisciplinary, and mixed-methods research may be valuable in advocacy efforts. The potential impact of evidence can be increased by “packaging” it as part of knowledge transfer and translation. Increased contact between researchers and policymakers could improve the uptake of research in policy processes. Researchers can play a role in advocacy efforts, although health professionals and disadvantaged people, who have direct contact with or experience of hardship, can be particularly persuasive in advocacy efforts. Different types of advocacy messages can accompany evidence, but messages should be tailored to advocacy target. Several barriers hamper advocacy efforts. The most frequently cited in the academic literature are the current political and economic zeitgeist and related public opinion, which tend to blame disadvantaged people for their ill health, even though biomedical approaches to health and political short-termism also act as barriers. These barriers could be tackled through long-term actions to raise public awareness and understanding of the SDH and through training of health professionals in advocacy. Advocates need to take advantage of “windows of opportunity,” which open and close quickly, and demonstrate expertise and credibility. Conclusions This article brings together for the first time evidence from the academic and the gray literature and provides a building block for efforts to advocate for health equity. Evidence regarding many of the dimensions is scant, and additional research is merited, particularly concerning the applicability of findings outside the English-speaking world. Advocacy organizations have a central role in advocating for health equity, given the challenges bridging the worlds of civil society, research, and policy. PMID:26044634

Delimiting family in syntheses of research on childhood chronic conditions and family life.

PubMed

Knafl, Kathleen; Leeman, Jennifer; Havill, Nancy; Crandell, Jamie; Sandelowski, Margarete

2015-03-01

Synthesis of family research presents unique challenges to investigators who must delimit what will be included as a family study in the proposed review. In this paper, the authors discuss the conceptual and pragmatic challenges of conducting systematic reviews of the literature on the intersection between family life and childhood chronic conditions. A proposed framework for delimiting the family domain of interest is presented. The framework addresses both topical salience and level of relevance and provides direction to future researchers, with the goal of supporting the overall quality of family research synthesis efforts. For users of synthesis studies, knowledge of how investigators conceptualize the boundaries of family research is important contextual information for understanding the limits and applicability of the results. © 2014 Family Process Institute.

Cooperative Vehicular Networking: A Survey

PubMed Central

Ahmed, Ejaz

2018-01-01

With the remarkable progress of cooperative communication technology in recent years, its transformation to vehicular networking is gaining momentum. Such a transformation has brought a new research challenge in facing the realization of cooperative vehicular networking (CVN). This paper presents a comprehensive survey of recent advances in the field of CVN. We cover important aspects of CVN research, including physical, medium access control, and routing protocols, as well as link scheduling and security. We also classify these research efforts in a taxonomy of cooperative vehicular networks. A set of key requirements for realizing the vision of cooperative vehicular networks is then identified and discussed. We also discuss open research challenges in enabling CVN. Lastly, the paper concludes by highlighting key points of research and future directions in the domain of CVN. PMID:29881331

Polar Kerr effect studies of time reversal symmetry breaking states in heavy fermion superconductors

DOE PAGES

Schemm, E. R.; Levenson-Falk, E. M.; Kapitulnik, A.

2016-11-30

The connection between chiral superconductivity and topological order has emerged as an active direction in research as more instances of both have been identified in condensed matter systems. Moreover, with the notable exception of 3He-B, all of the known or suspected chiral – that is to say time-reversal symmetry-breaking (TRSB) – superfluids arise in heavy fermion superconductors, although the vast majority of heavy fermion superconductors preserve time-reversal symmetry. We review recent experimental efforts to identify TRSB states in heavy fermion systems via measurement of polar Kerr effect, which is a direct consequence of TRSB.

Research and analysis of head-directed area-of-interest visual system concepts

NASA Technical Reports Server (NTRS)

Sinacori, J. B.

1983-01-01

An analysis and survey with conjecture supporting a preliminary data base design is presented. The data base is intended for use in a Computer Image Generator visual subsystem for a rotorcraft flight simulator that is used for rotorcraft systems development, not training. The approach taken was to attempt to identify the visual perception strategies used during terrain flight, survey environmental and image generation factors, and meld these into a preliminary data base design. This design is directed at Data Base developers, and hopefully will stimulate and aid their efforts to evolve such a Base that will support simulation of terrain flight operations.

The operant-respondent distinction: Future directions

PubMed Central

Pear, Joseph J.; Eldridge, Gloria D.

1984-01-01

The operant-respondent distinction has provided a major organizing framework for the data generated through the experimental analysis of behavior. Problems have been encountered, however, in using it as an explanatory concept for such phenomena as avoidance and conditioned suppression. Data now exist that do not fit neatly into the framework. Moreover, the discovery of autoshaping has highlighted difficulties in isolating the two types of behavior and conditioning. Despite these problems, the operant-respondent framework remains the most successful paradigm currently available for organizing behavioral data. Research and theoretical efforts should therefore probably be directed to modifying the framework to account for disparate data. PMID:16812402

The BIG Bell Test: quantum physics experiments with direct public participation

NASA Astrophysics Data System (ADS)

Mitchell, Morgan; Abellan, Carlos; Tura, Jordi; Garcia Matos, Marta; Hirschmann, Alina; Beduini, Federica; Pruneri, Valerio; Acin, Antonio; Marti, Maria; BIG Bell Test Collaboration

The BIG Bell Test is a suite of physics experiments - tests of quantum nonlocality, quantum communications, and related experiments - that use crowd-sourced human randomness as an experimental resource. By connecting participants - anyone with an internet connection - to state-of-the-art experiments on five continents, the project aims at two complementary goals: 1) to provide bits generated directly from human choices, a unique information resource, to physics experiments, and 2) to give the world public the opportunity to contribute in a meaningful way to quantum physics research. We also describe related outreach and educational efforts to spread awareness of quantum physics and its applications.

Flights of Discovery: 50 Years at the NASA Dryden Flight Research Center

NASA Technical Reports Server (NTRS)

Wallace, Lance E.

1996-01-01

As part of the NASA History Series, this report (NASA SP-4309) describes fifty years of aeronautical research at the NASA Dryden Flight Research Center. Starting with early efforts to exceed the speed of sound with the X-1 aircraft, and continuing through to the X-31 research aircraft, the report covers the flight activities of all of the major research aircraft and lifting bodies studied by NASA. Chapter One, 'A Place for Discovery', describes the facility itself and the surrounding Mojave Desert. Chapter Two, 'The Right Stuff', is about the people involved in the flight research programs. Chapter Three, 'Higher, Faster' summarizes the early years of transonic flight testing and the development of several lifting bodies. Chapter Four, 'Improving Efficiency, Maneuverability & Systems', outlines the development of aeronautical developments such as the supercritical wing, the mission adaptive wing, and various techniques for improving maneuverability fo winged aircraft. Chapter 5, 'Supporting National Efforts', shows how the research activities carried out at Dryden fit into NASA's programs across the country in supporting the space program, in safety and in problem solving related to aircraft design and aviation safety in general. Chapter Six, ' Future Directions' looks to future research building on the fifty year history of aeronautical research at the Dryden Flight Research Center. A glossary of acronyms and an appendix covering concepts and innovations are included. The report also contains many photographs providing a graphical perspective to the historical record.

A Survey of Keystroke Dynamics Biometrics

PubMed Central

Yue, Shigang

2013-01-01

Research on keystroke dynamics biometrics has been increasing, especially in the last decade. The main motivation behind this effort is due to the fact that keystroke dynamics biometrics is economical and can be easily integrated into the existing computer security systems with minimal alteration and user intervention. Numerous studies have been conducted in terms of data acquisition devices, feature representations, classification methods, experimental protocols, and evaluations. However, an up-to-date extensive survey and evaluation is not yet available. The objective of this paper is to provide an insightful survey and comparison on keystroke dynamics biometrics research performed throughout the last three decades, as well as offering suggestions and possible future research directions. PMID:24298216

KSC-02pd0618

NASA Image and Video Library

2002-04-29

KENNEDY SPACE CENTER, FLA. -- Robert Ferl, professor in the horticultural sciences department and assistant director of the University of Florida Biotechnology Program, speaks during the opening ceremony to launch a new program called SABRE, Space Agricultural Biotechnology Research and Education, that involves UF and NASA. SABRE will focus on the discovery, development and application of the biological aspects of advanced life support strategies. The program will include faculty from UF's Institute of Food and Agricultural Sciences, who will be located at both KSC - in the state-owned Space Experiment Research and Processing Laboratory (SERPL) being built there - and UF in Gainesville. Ferl will direct and be responsible for coordinating the research and education efforts of UF and NASA.

History and trends of bioactive glass-ceramics.

PubMed

Montazerian, Maziar; Dutra Zanotto, Edgar

2016-05-01

The interest around bioactive glass-ceramics (GCs) has grown significantly over the last two decades due to their appropriate biochemical and mechanical properties. The intense research effort in this field has led to some new commercial products for biomedical applications. This review article begins with the basic concepts of GC processing and development via controlled heat treatments of monolithic pieces or sinter-crystallization of powdered glasses. We then go on to describe the processing, properties, and applications of some commercial bioactive GCs and discuss selected valuable reported researches on several promising types of bioactive GCs. The article finishes with a section on open relevant research directions for bioactive GC development. © 2016 Wiley Periodicals, Inc.

Advocacy, partnership and political commitment for TB vaccine research.

PubMed

Olesen, Ole F; Chan, Sharon; Chappell, Janice; Guo, Yan; Leite, Luciana C C

2016-08-01

The 4th Global Forum on TB Vaccines, convened in Shanghai, China, from 21 - 24 April 2015, brought together a wide and diverse community involved in tuberculosis vaccine research and development to discuss the current status of, and future directions for this critical effort. This paper summarizes the sessions on Advancing the Pipeline: A Vision for the Next Decade, Engaging the BRICS: Basic Research to Manufacturing, and Regulatory and Access Issues for New TB Vaccines. Summaries of all sessions from the 4th Global Forum are compiled in a special supplement of Tuberculosis. [August 2016, Vol 99, Supp S1, S1-S30]. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Arbuscular mycorrhizal symbiosis for sustainable cultivation of Chinese medicinal plants: a promising research direction.

PubMed

Zeng, Yan; Guo, Lan-Ping; Chen, Bao-Dong; Hao, Zhi-Peng; Wang, Ji-Yong; Huang, Lu-Qi; Yang, Guang; Cui, Xiu-Ming; Yang, Li; Wu, Zhao-Xiang; Chen, Mei-Lan; Zhang, Yan

2013-01-01

Arbuscular mycorrhizal (AM) are symbiotic systems in nature and have great significance in promoting the growth and stress resistance of medicinal plants. During our literature search from the Chinese Scientific Information Database (Chinese National Knowledge Infrastructure, CNKI) we obtained 65 articles with "AM fungi" and "medicinal plant" as the key words, which indicates that in China, research efforts on these topics have been increasing. The main purposes of this review are to discuss the effects of mycorrhiza on the active ingredients of Chinese medicinal plants in comparison with results obtained in other plants in studies conducted by the international research community, and to introduce works published in Chinese journals to international colleagues.

Contribution of Spaceflight Environmental Factors to Vision Risks

NASA Technical Reports Server (NTRS)

Zanello, Susana

2012-01-01

The recognition of a risk of visual impairment and intracranial pressure increase as a result of spaceflight has directed our attention and research efforts to the eye. While the alterations observed in astronauts returning from long duration missions include reportable vision and neuroanatomical changes observed by non-invasive methods, other effects and subsequent tissue responses at the molecular and cellular level can only be studied by accessing the tissue itself. As a result of this need, several studies are currently taking place that use animal models for eye research within the HHC Element. The implementation of these studies represents a significant addition to the capabilities of the biomedical research laboratories within the SK3 branch at JSC.

An Open, Large-Scale, Collaborative Effort to Estimate the Reproducibility of Psychological Science.

PubMed

2012-11-01

Reproducibility is a defining feature of science. However, because of strong incentives for innovation and weak incentives for confirmation, direct replication is rarely practiced or published. The Reproducibility Project is an open, large-scale, collaborative effort to systematically examine the rate and predictors of reproducibility in psychological science. So far, 72 volunteer researchers from 41 institutions have organized to openly and transparently replicate studies published in three prominent psychological journals in 2008. Multiple methods will be used to evaluate the findings, calculate an empirical rate of replication, and investigate factors that predict reproducibility. Whatever the result, a better understanding of reproducibility will ultimately improve confidence in scientific methodology and findings. © The Author(s) 2012.