Multiple Sensor Camera for Enhanced Video Capturing
NASA Astrophysics Data System (ADS)
Nagahara, Hajime; Kanki, Yoshinori; Iwai, Yoshio; Yachida, Masahiko
A resolution of camera has been drastically improved under a current request for high-quality digital images. For example, digital still camera has several mega pixels. Although a video camera has the higher frame-rate, the resolution of a video camera is lower than that of still camera. Thus, the high-resolution is incompatible with the high frame rate of ordinary cameras in market. It is difficult to solve this problem by a single sensor, since it comes from physical limitation of the pixel transfer rate. In this paper, we propose a multi-sensor camera for capturing a resolution and frame-rate enhanced video. Common multi-CCDs camera, such as 3CCD color camera, has same CCD for capturing different spectral information. Our approach is to use different spatio-temporal resolution sensors in a single camera cabinet for capturing higher resolution and frame-rate information separately. We build a prototype camera which can capture high-resolution (2588×1958 pixels, 3.75 fps) and high frame-rate (500×500, 90 fps) videos. We also proposed the calibration method for the camera. As one of the application of the camera, we demonstrate an enhanced video (2128×1952 pixels, 90 fps) generated from the captured videos for showing the utility of the camera.
NASA Technical Reports Server (NTRS)
Ziemke, Robert A.
1990-01-01
The objective of the High Resolution, High Frame Rate Video Technology (HHVT) development effort is to provide technology advancements to remove constraints on the amount of high speed, detailed optical data recorded and transmitted for microgravity science and application experiments. These advancements will enable the development of video systems capable of high resolution, high frame rate video data recording, processing, and transmission. Techniques such as multichannel image scan, video parameter tradeoff, and the use of dual recording media were identified as methods of making the most efficient use of the near-term technology.
NASA Astrophysics Data System (ADS)
Lazarev, Grigory; Bonifer, Stefanie; Engel, Philip; Höhne, Daniel; Notni, Gunther
2017-06-01
We report about the implementation of the liquid crystal on silicon (LCOS) microdisplay with 1920 by 1080 resolution and 720 Hz frame rate. The driving solution is FPGA-based. The input signal is converted from the ultrahigh-resolution HDMI 2.0 signal into HD frames, which follow with the specified 720 Hz frame rate. Alternatively the signal is generated directly on the FPGA with built-in pattern generator. The display is showing switching times below 1.5 ms for the selected working temperature. The bit depth of the addressed image achieves 8 bit within each frame. The microdisplay is used in the fringe projection-based 3D sensing system, implemented by Fraunhofer IOF.
Super-resolution imaging applied to moving object tracking
NASA Astrophysics Data System (ADS)
Swalaganata, Galandaru; Ratna Sulistyaningrum, Dwi; Setiyono, Budi
2017-10-01
Moving object tracking in a video is a method used to detect and analyze changes that occur in an object that being observed. Visual quality and the precision of the tracked target are highly wished in modern tracking system. The fact that the tracked object does not always seem clear causes the tracking result less precise. The reasons are low quality video, system noise, small object, and other factors. In order to improve the precision of the tracked object especially for small object, we propose a two step solution that integrates a super-resolution technique into tracking approach. First step is super-resolution imaging applied into frame sequences. This step was done by cropping the frame in several frame or all of frame. Second step is tracking the result of super-resolution images. Super-resolution image is a technique to obtain high-resolution images from low-resolution images. In this research single frame super-resolution technique is proposed for tracking approach. Single frame super-resolution was a kind of super-resolution that it has the advantage of fast computation time. The method used for tracking is Camshift. The advantages of Camshift was simple calculation based on HSV color that use its histogram for some condition and color of the object varies. The computational complexity and large memory requirements required for the implementation of super-resolution and tracking were reduced and the precision of the tracked target was good. Experiment showed that integrate a super-resolution imaging into tracking technique can track the object precisely with various background, shape changes of the object, and in a good light conditions.
Large Area Field of View for Fast Temporal Resolution Astronomy
NASA Astrophysics Data System (ADS)
Covarrubias, Ricardo A.
2018-01-01
Scientific CMOS (sCMOS) technology is especially relevant for high temporal resolution astronomy combining high resolution, large field of view with very fast frame rates, without sacrificing ultra-low noise performance. Solar Astronomy, Near Earth Object detections, Space Debris Tracking, Transient Observations or Wavefront Sensing are among the many applications this technology can be utilized. Andor Technology is currently developing the next-generation, very large area sCMOS camera with an extremely low noise, rapid frame rates, high resolution and wide dynamic range.
Sajjad, Muhammad; Mehmood, Irfan; Baik, Sung Wook
2014-01-01
Visual sensor networks (VSNs) usually generate a low-resolution (LR) frame-sequence due to energy and processing constraints. These LR-frames are not very appropriate for use in certain surveillance applications. It is very important to enhance the resolution of the captured LR-frames using resolution enhancement schemes. In this paper, an effective framework for a super-resolution (SR) scheme is proposed that enhances the resolution of LR key-frames extracted from frame-sequences captured by visual-sensors. In a VSN, a visual processing hub (VPH) collects a huge amount of visual data from camera sensors. In the proposed framework, at the VPH, key-frames are extracted using our recent key-frame extraction technique and are streamed to the base station (BS) after compression. A novel effective SR scheme is applied at BS to produce a high-resolution (HR) output from the received key-frames. The proposed SR scheme uses optimized orthogonal matching pursuit (OOMP) for sparse-representation recovery in SR. OOMP does better in terms of detecting true sparsity than orthogonal matching pursuit (OMP). This property of the OOMP helps produce a HR image which is closer to the original image. The K-SVD dictionary learning procedure is incorporated for dictionary learning. Batch-OMP improves the dictionary learning process by removing the limitation in handling a large set of observed signals. Experimental results validate the effectiveness of the proposed scheme and show its superiority over other state-of-the-art schemes. PMID:24566632
Sajjad, Muhammad; Mehmood, Irfan; Baik, Sung Wook
2014-02-21
Visual sensor networks (VSNs) usually generate a low-resolution (LR) frame-sequence due to energy and processing constraints. These LR-frames are not very appropriate for use in certain surveillance applications. It is very important to enhance the resolution of the captured LR-frames using resolution enhancement schemes. In this paper, an effective framework for a super-resolution (SR) scheme is proposed that enhances the resolution of LR key-frames extracted from frame-sequences captured by visual-sensors. In a VSN, a visual processing hub (VPH) collects a huge amount of visual data from camera sensors. In the proposed framework, at the VPH, key-frames are extracted using our recent key-frame extraction technique and are streamed to the base station (BS) after compression. A novel effective SR scheme is applied at BS to produce a high-resolution (HR) output from the received key-frames. The proposed SR scheme uses optimized orthogonal matching pursuit (OOMP) for sparse-representation recovery in SR. OOMP does better in terms of detecting true sparsity than orthogonal matching pursuit (OMP). This property of the OOMP helps produce a HR image which is closer to the original image. The K-SVD dictionary learning procedure is incorporated for dictionary learning. Batch-OMP improves the dictionary learning process by removing the limitation in handling a large set of observed signals. Experimental results validate the effectiveness of the proposed scheme and show its superiority over other state-of-the-art schemes.
Spread-Spectrum Beamforming and Clutter Filtering for Plane-Wave Color Doppler Imaging.
Mansour, Omar; Poepping, Tamie L; Lacefield, James C
2016-07-21
Plane-wave imaging is desirable for its ability to achieve high frame rates, allowing the capture of fast dynamic events and continuous Doppler data. In most implementations of plane-wave imaging, multiple low-resolution images from different plane wave tilt angles are compounded to form a single high-resolution image, thereby reducing the frame rate. Compounding improves the lateral beam profile in the high-resolution image, but it also acts as a low-pass filter in slow time that causes attenuation and aliasing of signals with high Doppler shifts. This paper introduces a spread-spectrum color Doppler imaging method that produces high-resolution images without the use of compounding, thereby eliminating the tradeoff between beam quality, maximum unaliased Doppler frequency, and frame rate. The method uses a long, random sequence of transmit angles rather than a linear sweep of plane wave directions. The random angle sequence randomizes the phase of off-focus (clutter) signals, thereby spreading the clutter power in the Doppler spectrum, while keeping the spectrum of the in-focus signal intact. The ensemble of randomly tilted low-resolution frames also acts as the Doppler ensemble, so it can be much longer than a conventional linear sweep, thereby improving beam formation while also making the slow-time Doppler sampling frequency equal to the pulse repetition frequency. Experiments performed using a carotid artery phantom with constant flow demonstrate that the spread-spectrum method more accurately measures the parabolic flow profile of the vessel and outperforms conventional plane-wave Doppler in both contrast resolution and estimation of high flow velocities. The spread-spectrum method is expected to be valuable for Doppler applications that require measurement of high velocities at high frame rates.
High resolution metric imaging payload
NASA Astrophysics Data System (ADS)
Delclaud, Y.
2017-11-01
Alcatel Space Industries has become Europe's leader in the field of high and very high resolution optical payloads, in the frame work of earth observation system able to provide military government with metric images from space. This leadership allowed ALCATEL to propose for the export market, within a French collaboration frame, a complete space based system for metric observation.
Automated frame selection process for high-resolution microendoscopy
NASA Astrophysics Data System (ADS)
Ishijima, Ayumu; Schwarz, Richard A.; Shin, Dongsuk; Mondrik, Sharon; Vigneswaran, Nadarajah; Gillenwater, Ann M.; Anandasabapathy, Sharmila; Richards-Kortum, Rebecca
2015-04-01
We developed an automated frame selection algorithm for high-resolution microendoscopy video sequences. The algorithm rapidly selects a representative frame with minimal motion artifact from a short video sequence, enabling fully automated image analysis at the point-of-care. The algorithm was evaluated by quantitative comparison of diagnostically relevant image features and diagnostic classification results obtained using automated frame selection versus manual frame selection. A data set consisting of video sequences collected in vivo from 100 oral sites and 167 esophageal sites was used in the analysis. The area under the receiver operating characteristic curve was 0.78 (automated selection) versus 0.82 (manual selection) for oral sites, and 0.93 (automated selection) versus 0.92 (manual selection) for esophageal sites. The implementation of fully automated high-resolution microendoscopy at the point-of-care has the potential to reduce the number of biopsies needed for accurate diagnosis of precancer and cancer in low-resource settings where there may be limited infrastructure and personnel for standard histologic analysis.
High-frame-rate full-vocal-tract 3D dynamic speech imaging.
Fu, Maojing; Barlaz, Marissa S; Holtrop, Joseph L; Perry, Jamie L; Kuehn, David P; Shosted, Ryan K; Liang, Zhi-Pei; Sutton, Bradley P
2017-04-01
To achieve high temporal frame rate, high spatial resolution and full-vocal-tract coverage for three-dimensional dynamic speech MRI by using low-rank modeling and sparse sampling. Three-dimensional dynamic speech MRI is enabled by integrating a novel data acquisition strategy and an image reconstruction method with the partial separability model: (a) a self-navigated sparse sampling strategy that accelerates data acquisition by collecting high-nominal-frame-rate cone navigator sand imaging data within a single repetition time, and (b) are construction method that recovers high-quality speech dynamics from sparse (k,t)-space data by enforcing joint low-rank and spatiotemporal total variation constraints. The proposed method has been evaluated through in vivo experiments. A nominal temporal frame rate of 166 frames per second (defined based on a repetition time of 5.99 ms) was achieved for an imaging volume covering the entire vocal tract with a spatial resolution of 2.2 × 2.2 × 5.0 mm 3 . Practical utility of the proposed method was demonstrated via both validation experiments and a phonetics investigation. Three-dimensional dynamic speech imaging is possible with full-vocal-tract coverage, high spatial resolution and high nominal frame rate to provide dynamic speech data useful for phonetic studies. Magn Reson Med 77:1619-1629, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.
SkySat-1: very high-resolution imagery from a small satellite
NASA Astrophysics Data System (ADS)
Murthy, Kiran; Shearn, Michael; Smiley, Byron D.; Chau, Alexandra H.; Levine, Josh; Robinson, M. Dirk
2014-10-01
This paper presents details of the SkySat-1 mission, which is the first microsatellite-class commercial earth- observation system to generate sub-meter resolution panchromatic imagery, in addition to sub-meter resolution 4-band pan-sharpened imagery. SkySat-1 was built and launched for an order of magnitude lower cost than similarly performing missions. The low-cost design enables the deployment of a large imaging constellation that can provide imagery with both high temporal resolution and high spatial resolution. One key enabler of the SkySat-1 mission was simplifying the spacecraft design and instead relying on ground- based image processing to achieve high-performance at the system level. The imaging instrument consists of a custom-designed high-quality optical telescope and commercially-available high frame rate CMOS image sen- sors. While each individually captured raw image frame shows moderate quality, ground-based image processing algorithms improve the raw data by combining data from multiple frames to boost image signal-to-noise ratio (SNR) and decrease the ground sample distance (GSD) in a process Skybox calls "digital TDI". Careful qual-ity assessment and tuning of the spacecraft, payload, and algorithms was necessary to generate high-quality panchromatic, multispectral, and pan-sharpened imagery. Furthermore, the framing sensor configuration en- abled the first commercial High-Definition full-frame rate panchromatic video to be captured from space, with approximately 1 meter ground sample distance. Details of the SkySat-1 imaging instrument and ground-based image processing system are presented, as well as an overview of the work involved with calibrating and validating the system. Examples of raw and processed imagery are shown, and the raw imagery is compared to pre-launch simulated imagery used to tune the image processing algorithms.
High-speed adaptive optics line scan confocal retinal imaging for human eye
Wang, Xiaolin; Zhang, Yuhua
2017-01-01
Purpose Continuous and rapid eye movement causes significant intraframe distortion in adaptive optics high resolution retinal imaging. To minimize this artifact, we developed a high speed adaptive optics line scan confocal retinal imaging system. Methods A high speed line camera was employed to acquire retinal image and custom adaptive optics was developed to compensate the wave aberration of the human eye’s optics. The spatial resolution and signal to noise ratio were assessed in model eye and in living human eye. The improvement of imaging fidelity was estimated by reduction of intra-frame distortion of retinal images acquired in the living human eyes with frame rates at 30 frames/second (FPS), 100 FPS, and 200 FPS. Results The device produced retinal image with cellular level resolution at 200 FPS with a digitization of 512×512 pixels/frame in the living human eye. Cone photoreceptors in the central fovea and rod photoreceptors near the fovea were resolved in three human subjects in normal chorioretinal health. Compared with retinal images acquired at 30 FPS, the intra-frame distortion in images taken at 200 FPS was reduced by 50.9% to 79.7%. Conclusions We demonstrated the feasibility of acquiring high resolution retinal images in the living human eye at a speed that minimizes retinal motion artifact. This device may facilitate research involving subjects with nystagmus or unsteady fixation due to central vision loss. PMID:28257458
High-speed adaptive optics line scan confocal retinal imaging for human eye.
Lu, Jing; Gu, Boyu; Wang, Xiaolin; Zhang, Yuhua
2017-01-01
Continuous and rapid eye movement causes significant intraframe distortion in adaptive optics high resolution retinal imaging. To minimize this artifact, we developed a high speed adaptive optics line scan confocal retinal imaging system. A high speed line camera was employed to acquire retinal image and custom adaptive optics was developed to compensate the wave aberration of the human eye's optics. The spatial resolution and signal to noise ratio were assessed in model eye and in living human eye. The improvement of imaging fidelity was estimated by reduction of intra-frame distortion of retinal images acquired in the living human eyes with frame rates at 30 frames/second (FPS), 100 FPS, and 200 FPS. The device produced retinal image with cellular level resolution at 200 FPS with a digitization of 512×512 pixels/frame in the living human eye. Cone photoreceptors in the central fovea and rod photoreceptors near the fovea were resolved in three human subjects in normal chorioretinal health. Compared with retinal images acquired at 30 FPS, the intra-frame distortion in images taken at 200 FPS was reduced by 50.9% to 79.7%. We demonstrated the feasibility of acquiring high resolution retinal images in the living human eye at a speed that minimizes retinal motion artifact. This device may facilitate research involving subjects with nystagmus or unsteady fixation due to central vision loss.
Proximity correction of high-dosed frame with PROXECCO
NASA Astrophysics Data System (ADS)
Eisenmann, Hans; Waas, Thomas; Hartmann, Hans
1994-05-01
Usefulness of electron beam lithography is strongly related to the efficiency and quality of methods used for proximity correction. This paper addresses the above issue by proposing an extension to the new proximity correction program PROXECCO. The combination of a framing step with PROXECCO produces a pattern with a very high edge accuracy and still allows usage of the fast correction procedure. Making a frame with a higher dose imitates a fine resolution correction where the coarse part is disregarded. So after handling the high resolution effect by means of framing, an additional coarse correction is still needed. Higher doses have a higher contribution to the proximity effect. This additional proximity effect is taken into account with the help of the multi-dose input of PROXECCO. The dose of the frame is variable, depending on the deposited energy coming from backscattering of the proximity. Simulation proves the very high edge accuracy of the applied method.
Toshiba TDF-500 High Resolution Viewing And Analysis System
NASA Astrophysics Data System (ADS)
Roberts, Barry; Kakegawa, M.; Nishikawa, M.; Oikawa, D.
1988-06-01
A high resolution, operator interactive, medical viewing and analysis system has been developed by Toshiba and Bio-Imaging Research. This system provides many advanced features including high resolution displays, a very large image memory and advanced image processing capability. In particular, the system provides CRT frame buffers capable of update in one frame period, an array processor capable of image processing at operator interactive speeds, and a memory system capable of updating multiple frame buffers at frame rates whilst supporting multiple array processors. The display system provides 1024 x 1536 display resolution at 40Hz frame and 80Hz field rates. In particular, the ability to provide whole or partial update of the screen at the scanning rate is a key feature. This allows multiple viewports or windows in the display buffer with both fixed and cine capability. To support image processing features such as windowing, pan, zoom, minification, filtering, ROI analysis, multiplanar and 3D reconstruction, a high performance CPU is integrated into the system. This CPU is an array processor capable of up to 400 million instructions per second. To support the multiple viewer and array processors' instantaneous high memory bandwidth requirement, an ultra fast memory system is used. This memory system has a bandwidth capability of 400MB/sec and a total capacity of 256MB. This bandwidth is more than adequate to support several high resolution CRT's and also the fast processing unit. This fully integrated approach allows effective real time image processing. The integrated design of viewing system, memory system and array processor are key to the imaging system. It is the intention to describe the architecture of the image system in this paper.
High-resolution dynamic 31 P-MRSI using a low-rank tensor model.
Ma, Chao; Clifford, Bryan; Liu, Yuchi; Gu, Yuning; Lam, Fan; Yu, Xin; Liang, Zhi-Pei
2017-08-01
To develop a rapid 31 P-MRSI method with high spatiospectral resolution using low-rank tensor-based data acquisition and image reconstruction. The multidimensional image function of 31 P-MRSI is represented by a low-rank tensor to capture the spatial-spectral-temporal correlations of data. A hybrid data acquisition scheme is used for sparse sampling, which consists of a set of "training" data with limited k-space coverage to capture the subspace structure of the image function, and a set of sparsely sampled "imaging" data for high-resolution image reconstruction. An explicit subspace pursuit approach is used for image reconstruction, which estimates the bases of the subspace from the "training" data and then reconstructs a high-resolution image function from the "imaging" data. We have validated the feasibility of the proposed method using phantom and in vivo studies on a 3T whole-body scanner and a 9.4T preclinical scanner. The proposed method produced high-resolution static 31 P-MRSI images (i.e., 6.9 × 6.9 × 10 mm 3 nominal resolution in a 15-min acquisition at 3T) and high-resolution, high-frame-rate dynamic 31 P-MRSI images (i.e., 1.5 × 1.5 × 1.6 mm 3 nominal resolution, 30 s/frame at 9.4T). Dynamic spatiospectral variations of 31 P-MRSI signals can be efficiently represented by a low-rank tensor. Exploiting this mathematical structure for data acquisition and image reconstruction can lead to fast 31 P-MRSI with high resolution, frame-rate, and SNR. Magn Reson Med 78:419-428, 2017. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.
Shen, Kai; Lu, Hui; Baig, Sarfaraz; Wang, Michael R
2017-11-01
The multi-frame superresolution technique is introduced to significantly improve the lateral resolution and image quality of spectral domain optical coherence tomography (SD-OCT). Using several sets of low resolution C-scan 3D images with lateral sub-spot-spacing shifts on different sets, the multi-frame superresolution processing of these sets at each depth layer reconstructs a higher resolution and quality lateral image. Layer by layer processing yields an overall high lateral resolution and quality 3D image. In theory, the superresolution processing including deconvolution can solve the diffraction limit, lateral scan density and background noise problems together. In experiment, the improved lateral resolution by ~3 times reaching 7.81 µm and 2.19 µm using sample arm optics of 0.015 and 0.05 numerical aperture respectively as well as doubling the image quality has been confirmed by imaging a known resolution test target. Improved lateral resolution on in vitro skin C-scan images has been demonstrated. For in vivo 3D SD-OCT imaging of human skin, fingerprint and retina layer, we used the multi-modal volume registration method to effectively estimate the lateral image shifts among different C-scans due to random minor unintended live body motion. Further processing of these images generated high lateral resolution 3D images as well as high quality B-scan images of these in vivo tissues.
Lindsey, Brooks D; Shelton, Sarah E; Martin, K Heath; Ozgun, Kathryn A; Rojas, Juan D; Foster, F Stuart; Dayton, Paul A
2017-04-01
Mapping blood perfusion quantitatively allows localization of abnormal physiology and can improve understanding of disease progression. Dynamic contrast-enhanced ultrasound is a low-cost, real-time technique for imaging perfusion dynamics with microbubble contrast agents. Previously, we have demonstrated another contrast agent-specific ultrasound imaging technique, acoustic angiography, which forms static anatomical images of the superharmonic signal produced by microbubbles. In this work, we seek to determine whether acoustic angiography can be utilized for high resolution perfusion imaging in vivo by examining the effect of acquisition rate on superharmonic imaging at low flow rates and demonstrating the feasibility of dynamic contrast-enhanced superharmonic perfusion imaging for the first time. Results in the chorioallantoic membrane model indicate that frame rate and frame averaging do not affect the measured diameter of individual vessels observed, but that frame rate does influence the detection of vessels near and below the resolution limit. The highest number of resolvable vessels was observed at an intermediate frame rate of 3 Hz using a mechanically-steered prototype transducer. We also demonstrate the feasibility of quantitatively mapping perfusion rate in 2D in a mouse model with spatial resolution of ~100 μm. This type of imaging could provide non-invasive, high resolution quantification of microvascular function at penetration depths of several centimeters.
NASA Astrophysics Data System (ADS)
Boon, Choong S.; Guleryuz, Onur G.; Kawahara, Toshiro; Suzuki, Yoshinori
2006-08-01
We consider the mobile service scenario where video programming is broadcast to low-resolution wireless terminals. In such a scenario, broadcasters utilize simultaneous data services and bi-directional communications capabilities of the terminals in order to offer substantially enriched viewing experiences to users by allowing user participation and user tuned content. While users immediately benefit from this service when using their phones in mobile environments, the service is less appealing in stationary environments where a regular television provides competing programming at much higher display resolutions. We propose a fast super-resolution technique that allows the mobile terminals to show a much enhanced version of the broadcast video on nearby high-resolution devices, extending the appeal and usefulness of the broadcast service. The proposed single frame super-resolution algorithm uses recent sparse recovery results to provide high quality and high-resolution video reconstructions based solely on individual decoded frames provided by the low-resolution broadcast.
Can You See Me Now Visualizing Battlefield Facial Recognition Technology in 2035
2010-04-01
County Sheriff’s Department, use certain measurements such as the distance between eyes, the length of the nose, or the shape of the ears. 8 However...captures multiple frames of video and composites them into an appropriately high-resolution image that can be processed by the facial recognition software...stream of data. High resolution video systems, such as those described below will be able to capture orders of magnitude more data in one video frame
Keleshis, C; Ionita, CN; Yadava, G; Patel, V; Bednarek, DR; Hoffmann, KR; Verevkin, A; Rudin, S
2008-01-01
A graphical user interface based on LabVIEW software was developed to enable clinical evaluation of a new High-Sensitivity Micro-Angio-Fluoroscopic (HSMAF) system for real-time acquisition, display and rapid frame transfer of high-resolution region-of-interest images. The HSMAF detector consists of a CsI(Tl) phosphor, a light image intensifier (LII), and a fiber-optic taper coupled to a progressive scan, frame-transfer, charged-coupled device (CCD) camera which provides real-time 12 bit, 1k × 1k images capable of greater than 10 lp/mm resolution. Images can be captured in continuous or triggered mode, and the camera can be programmed by a computer using Camera Link serial communication. A graphical user interface was developed to control the camera modes such as gain and pixel binning as well as to acquire, store, display, and process the images. The program, written in LabVIEW, has the following capabilities: camera initialization, synchronized image acquisition with the x-ray pulses, roadmap and digital subtraction angiography acquisition (DSA), flat field correction, brightness and contrast control, last frame hold in fluoroscopy, looped playback of the acquired images in angiography, recursive temporal filtering and LII gain control. Frame rates can be up to 30 fps in full-resolution mode. The user friendly implementation of the interface along with the high framerate acquisition and display for this unique high-resolution detector should provide angiographers and interventionalists with a new capability for visualizing details of small vessels and endovascular devices such as stents and hence enable more accurate diagnoses and image guided interventions. (Support: NIH Grants R01NS43924, R01EB002873) PMID:18836570
Keleshis, C; Ionita, Cn; Yadava, G; Patel, V; Bednarek, Dr; Hoffmann, Kr; Verevkin, A; Rudin, S
2008-01-01
A graphical user interface based on LabVIEW software was developed to enable clinical evaluation of a new High-Sensitivity Micro-Angio-Fluoroscopic (HSMAF) system for real-time acquisition, display and rapid frame transfer of high-resolution region-of-interest images. The HSMAF detector consists of a CsI(Tl) phosphor, a light image intensifier (LII), and a fiber-optic taper coupled to a progressive scan, frame-transfer, charged-coupled device (CCD) camera which provides real-time 12 bit, 1k × 1k images capable of greater than 10 lp/mm resolution. Images can be captured in continuous or triggered mode, and the camera can be programmed by a computer using Camera Link serial communication. A graphical user interface was developed to control the camera modes such as gain and pixel binning as well as to acquire, store, display, and process the images. The program, written in LabVIEW, has the following capabilities: camera initialization, synchronized image acquisition with the x-ray pulses, roadmap and digital subtraction angiography acquisition (DSA), flat field correction, brightness and contrast control, last frame hold in fluoroscopy, looped playback of the acquired images in angiography, recursive temporal filtering and LII gain control. Frame rates can be up to 30 fps in full-resolution mode. The user friendly implementation of the interface along with the high framerate acquisition and display for this unique high-resolution detector should provide angiographers and interventionalists with a new capability for visualizing details of small vessels and endovascular devices such as stents and hence enable more accurate diagnoses and image guided interventions. (Support: NIH Grants R01NS43924, R01EB002873).
Multi-frame super-resolution with quality self-assessment for retinal fundus videos.
Köhler, Thomas; Brost, Alexander; Mogalle, Katja; Zhang, Qianyi; Köhler, Christiane; Michelson, Georg; Hornegger, Joachim; Tornow, Ralf P
2014-01-01
This paper proposes a novel super-resolution framework to reconstruct high-resolution fundus images from multiple low-resolution video frames in retinal fundus imaging. Natural eye movements during an examination are used as a cue for super-resolution in a robust maximum a-posteriori scheme. In order to compensate heterogeneous illumination on the fundus, we integrate retrospective illumination correction for photometric registration to the underlying imaging model. Our method utilizes quality self-assessment to provide objective quality scores for reconstructed images as well as to select regularization parameters automatically. In our evaluation on real data acquired from six human subjects with a low-cost video camera, the proposed method achieved considerable enhancements of low-resolution frames and improved noise and sharpness characteristics by 74%. In terms of image analysis, we demonstrate the importance of our method for the improvement of automatic blood vessel segmentation as an example application, where the sensitivity was increased by 13% using super-resolution reconstruction.
Shen, Kai; Lu, Hui; Baig, Sarfaraz; Wang, Michael R.
2017-01-01
The multi-frame superresolution technique is introduced to significantly improve the lateral resolution and image quality of spectral domain optical coherence tomography (SD-OCT). Using several sets of low resolution C-scan 3D images with lateral sub-spot-spacing shifts on different sets, the multi-frame superresolution processing of these sets at each depth layer reconstructs a higher resolution and quality lateral image. Layer by layer processing yields an overall high lateral resolution and quality 3D image. In theory, the superresolution processing including deconvolution can solve the diffraction limit, lateral scan density and background noise problems together. In experiment, the improved lateral resolution by ~3 times reaching 7.81 µm and 2.19 µm using sample arm optics of 0.015 and 0.05 numerical aperture respectively as well as doubling the image quality has been confirmed by imaging a known resolution test target. Improved lateral resolution on in vitro skin C-scan images has been demonstrated. For in vivo 3D SD-OCT imaging of human skin, fingerprint and retina layer, we used the multi-modal volume registration method to effectively estimate the lateral image shifts among different C-scans due to random minor unintended live body motion. Further processing of these images generated high lateral resolution 3D images as well as high quality B-scan images of these in vivo tissues. PMID:29188089
Alam, M S; Bognar, J G; Cain, S; Yasuda, B J
1998-03-10
During the process of microscanning a controlled vibrating mirror typically is used to produce subpixel shifts in a sequence of forward-looking infrared (FLIR) images. If the FLIR is mounted on a moving platform, such as an aircraft, uncontrolled random vibrations associated with the platform can be used to generate the shifts. Iterative techniques such as the expectation-maximization (EM) approach by means of the maximum-likelihood algorithm can be used to generate high-resolution images from multiple randomly shifted aliased frames. In the maximum-likelihood approach the data are considered to be Poisson random variables and an EM algorithm is developed that iteratively estimates an unaliased image that is compensated for known imager-system blur while it simultaneously estimates the translational shifts. Although this algorithm yields high-resolution images from a sequence of randomly shifted frames, it requires significant computation time and cannot be implemented for real-time applications that use the currently available high-performance processors. The new image shifts are iteratively calculated by evaluation of a cost function that compares the shifted and interlaced data frames with the corresponding values in the algorithm's latest estimate of the high-resolution image. We present a registration algorithm that estimates the shifts in one step. The shift parameters provided by the new algorithm are accurate enough to eliminate the need for iterative recalculation of translational shifts. Using this shift information, we apply a simplified version of the EM algorithm to estimate a high-resolution image from a given sequence of video frames. The proposed modified EM algorithm has been found to reduce significantly the computational burden when compared with the original EM algorithm, thus making it more attractive for practical implementation. Both simulation and experimental results are presented to verify the effectiveness of the proposed technique.
Feng, Wei; Zhang, Fumin; Qu, Xinghua; Zheng, Shiwei
2016-01-01
High-speed photography is an important tool for studying rapid physical phenomena. However, low-frame-rate CCD (charge coupled device) or CMOS (complementary metal oxide semiconductor) camera cannot effectively capture the rapid phenomena with high-speed and high-resolution. In this paper, we incorporate the hardware restrictions of existing image sensors, design the sampling functions, and implement a hardware prototype with a digital micromirror device (DMD) camera in which spatial and temporal information can be flexibly modulated. Combined with the optical model of DMD camera, we theoretically analyze the per-pixel coded exposure and propose a three-element median quicksort method to increase the temporal resolution of the imaging system. Theoretically, this approach can rapidly increase the temporal resolution several, or even hundreds, of times without increasing bandwidth requirements of the camera. We demonstrate the effectiveness of our method via extensive examples and achieve 100 fps (frames per second) gain in temporal resolution by using a 25 fps camera. PMID:26959023
Feng, Wei; Zhang, Fumin; Qu, Xinghua; Zheng, Shiwei
2016-03-04
High-speed photography is an important tool for studying rapid physical phenomena. However, low-frame-rate CCD (charge coupled device) or CMOS (complementary metal oxide semiconductor) camera cannot effectively capture the rapid phenomena with high-speed and high-resolution. In this paper, we incorporate the hardware restrictions of existing image sensors, design the sampling functions, and implement a hardware prototype with a digital micromirror device (DMD) camera in which spatial and temporal information can be flexibly modulated. Combined with the optical model of DMD camera, we theoretically analyze the per-pixel coded exposure and propose a three-element median quicksort method to increase the temporal resolution of the imaging system. Theoretically, this approach can rapidly increase the temporal resolution several, or even hundreds, of times without increasing bandwidth requirements of the camera. We demonstrate the effectiveness of our method via extensive examples and achieve 100 fps (frames per second) gain in temporal resolution by using a 25 fps camera.
Cheetah: A high frame rate, high resolution SWIR image camera
NASA Astrophysics Data System (ADS)
Neys, Joel; Bentell, Jonas; O'Grady, Matt; Vermeiren, Jan; Colin, Thierry; Hooylaerts, Peter; Grietens, Bob
2008-10-01
A high resolution, high frame rate InGaAs based image sensor and associated camera has been developed. The sensor and the camera are capable of recording and delivering more than 1700 full 640x512pixel frames per second. The FPA utilizes a low lag CTIA current integrator in each pixel, enabling integration times shorter than one microsecond. On-chip logics allows for four different sub windows to be read out simultaneously at even higher rates. The spectral sensitivity of the FPA is situated in the SWIR range [0.9-1.7 μm] and can be further extended into the Visible and NIR range. The Cheetah camera has max 16 GB of on-board memory to store the acquired images and transfer the data over a Gigabit Ethernet connection to the PC. The camera is also equipped with a full CameralinkTM interface to directly stream the data to a frame grabber or dedicated image processing unit. The Cheetah camera is completely under software control.
Collection and Analysis of Crowd Data with Aerial, Rooftop, and Ground Views
2014-11-10
collected these datasets using different aircrafts. Erista 8 HL OctaCopter is a heavy-lift aerial platform capable of using high-resolution cinema ...is another high-resolution camera that is cinema grade and high quality, with the capability of capturing videos with 4K resolution at 30 frames per...292.58 Imaging Systems and Accessories Blackmagic Production Camera 4 Crowd Counting using 4K Cameras High resolution cinema grade digital video
Dynamic frame resizing with convolutional neural network for efficient video compression
NASA Astrophysics Data System (ADS)
Kim, Jaehwan; Park, Youngo; Choi, Kwang Pyo; Lee, JongSeok; Jeon, Sunyoung; Park, JeongHoon
2017-09-01
In the past, video codecs such as vc-1 and H.263 used a technique to encode reduced-resolution video and restore original resolution from the decoder for improvement of coding efficiency. The techniques of vc-1 and H.263 Annex Q are called dynamic frame resizing and reduced-resolution update mode, respectively. However, these techniques have not been widely used due to limited performance improvements that operate well only under specific conditions. In this paper, video frame resizing (reduced/restore) technique based on machine learning is proposed for improvement of coding efficiency. The proposed method features video of low resolution made by convolutional neural network (CNN) in encoder and reconstruction of original resolution using CNN in decoder. The proposed method shows improved subjective performance over all the high resolution videos which are dominantly consumed recently. In order to assess subjective quality of the proposed method, Video Multi-method Assessment Fusion (VMAF) which showed high reliability among many subjective measurement tools was used as subjective metric. Moreover, to assess general performance, diverse bitrates are tested. Experimental results showed that BD-rate based on VMAF was improved by about 51% compare to conventional HEVC. Especially, VMAF values were significantly improved in low bitrate. Also, when the method is subjectively tested, it had better subjective visual quality in similar bit rate.
High-resolution Ceres Low Altitude Mapping Orbit Atlas derived from Dawn Framing Camera images
NASA Astrophysics Data System (ADS)
Roatsch, Th.; Kersten, E.; Matz, K.-D.; Preusker, F.; Scholten, F.; Jaumann, R.; Raymond, C. A.; Russell, C. T.
2017-06-01
The Dawn spacecraft Framing Camera (FC) acquired over 31,300 clear filter images of Ceres with a resolution of about 35 m/pxl during the eleven cycles in the Low Altitude Mapping Orbit (LAMO) phase between December 16 2015 and August 8 2016. We ortho-rectified the images from the first four cycles and produced a global, high-resolution, uncontrolled photomosaic of Ceres. This global mosaic is the basis for a high-resolution Ceres atlas that consists of 62 tiles mapped at a scale of 1:250,000. The nomenclature used in this atlas was proposed by the Dawn team and was approved by the International Astronomical Union (IAU). The full atlas is available to the public through the Dawn Geographical Information System (GIS) web page [http://dawngis.dlr.de/atlas] and will become available through the NASA Planetary Data System (PDS) (http://pdssbn.astro.umd.edu/).
Study on a High Compression Processing for Video-on-Demand e-learning System
NASA Astrophysics Data System (ADS)
Nomura, Yoshihiko; Matsuda, Ryutaro; Sakamoto, Ryota; Sugiura, Tokuhiro; Matsui, Hirokazu; Kato, Norihiko
The authors proposed a high-quality and small-capacity lecture-video-file creating system for distance e-learning system. Examining the feature of the lecturing scene, the authors ingeniously employ two kinds of image-capturing equipment having complementary characteristics : one is a digital video camera with a low resolution and a high frame rate, and the other is a digital still camera with a high resolution and a very low frame rate. By managing the two kinds of image-capturing equipment, and by integrating them with image processing, we can produce course materials with the greatly reduced file capacity : the course materials satisfy the requirements both for the temporal resolution to see the lecturer's point-indicating actions and for the high spatial resolution to read the small written letters. As a result of a comparative experiment, the e-lecture using the proposed system was confirmed to be more effective than an ordinary lecture from the viewpoint of educational effect.
Ultra-fast high-resolution hybrid and monolithic CMOS imagers in multi-frame radiography
NASA Astrophysics Data System (ADS)
Kwiatkowski, Kris; Douence, Vincent; Bai, Yibin; Nedrow, Paul; Mariam, Fesseha; Merrill, Frank; Morris, Christopher L.; Saunders, Andy
2014-09-01
A new burst-mode, 10-frame, hybrid Si-sensor/CMOS-ROIC FPA chip has been recently fabricated at Teledyne Imaging Sensors. The intended primary use of the sensor is in the multi-frame 800 MeV proton radiography at LANL. The basic part of the hybrid is a large (48×49 mm2) stitched CMOS chip of 1100×1100 pixel count, with a minimum shutter speed of 50 ns. The performance parameters of this chip are compared to the first generation 3-frame 0.5-Mpixel custom hybrid imager. The 3-frame cameras have been in continuous use for many years, in a variety of static and dynamic experiments at LANSCE. The cameras can operate with a per-frame adjustable integration time of ~ 120ns-to- 1s, and inter-frame time of 250ns to 2s. Given the 80 ms total readout time, the original and the new imagers can be externally synchronized to 0.1-to-5 Hz, 50-ns wide proton beam pulses, and record up to ~1000-frame radiographic movies typ. of 3-to-30 minute duration. The performance of the global electronic shutter is discussed and compared to that of a high-resolution commercial front-illuminated monolithic CMOS imager.
Multiple signal classification algorithm for super-resolution fluorescence microscopy
Agarwal, Krishna; Macháň, Radek
2016-01-01
Single-molecule localization techniques are restricted by long acquisition and computational times, or the need of special fluorophores or biologically toxic photochemical environments. Here we propose a statistical super-resolution technique of wide-field fluorescence microscopy we call the multiple signal classification algorithm which has several advantages. It provides resolution down to at least 50 nm, requires fewer frames and lower excitation power and works even at high fluorophore concentrations. Further, it works with any fluorophore that exhibits blinking on the timescale of the recording. The multiple signal classification algorithm shows comparable or better performance in comparison with single-molecule localization techniques and four contemporary statistical super-resolution methods for experiments of in vitro actin filaments and other independently acquired experimental data sets. We also demonstrate super-resolution at timescales of 245 ms (using 49 frames acquired at 200 frames per second) in samples of live-cell microtubules and live-cell actin filaments imaged without imaging buffers. PMID:27934858
High resolution, wide field of view, real time 340GHz 3D imaging radar for security screening
NASA Astrophysics Data System (ADS)
Robertson, Duncan A.; Macfarlane, David G.; Hunter, Robert I.; Cassidy, Scott L.; Llombart, Nuria; Gandini, Erio; Bryllert, Tomas; Ferndahl, Mattias; Lindström, Hannu; Tenhunen, Jussi; Vasama, Hannu; Huopana, Jouni; Selkälä, Timo; Vuotikka, Antti-Jussi
2017-05-01
The EU FP7 project CONSORTIS (Concealed Object Stand-Off Real-Time Imaging for Security) is developing a demonstrator system for next generation airport security screening which will combine passive and active submillimeter wave imaging sensors. We report on the development of the 340 GHz 3D imaging radar which achieves high volumetric resolution over a wide field of view with high dynamic range and a high frame rate. A sparse array of 16 radar transceivers is coupled with high speed mechanical beam scanning to achieve a field of view of 1 x 1 x 1 m3 and a 10 Hz frame rate.
Video Super-Resolution via Bidirectional Recurrent Convolutional Networks.
Huang, Yan; Wang, Wei; Wang, Liang
2018-04-01
Super resolving a low-resolution video, namely video super-resolution (SR), is usually handled by either single-image SR or multi-frame SR. Single-Image SR deals with each video frame independently, and ignores intrinsic temporal dependency of video frames which actually plays a very important role in video SR. Multi-Frame SR generally extracts motion information, e.g., optical flow, to model the temporal dependency, but often shows high computational cost. Considering that recurrent neural networks (RNNs) can model long-term temporal dependency of video sequences well, we propose a fully convolutional RNN named bidirectional recurrent convolutional network for efficient multi-frame SR. Different from vanilla RNNs, 1) the commonly-used full feedforward and recurrent connections are replaced with weight-sharing convolutional connections. So they can greatly reduce the large number of network parameters and well model the temporal dependency in a finer level, i.e., patch-based rather than frame-based, and 2) connections from input layers at previous timesteps to the current hidden layer are added by 3D feedforward convolutions, which aim to capture discriminate spatio-temporal patterns for short-term fast-varying motions in local adjacent frames. Due to the cheap convolutional operations, our model has a low computational complexity and runs orders of magnitude faster than other multi-frame SR methods. With the powerful temporal dependency modeling, our model can super resolve videos with complex motions and achieve well performance.
Full-Frame Reference for Test Photo of Moon
2005-09-10
This pair of views shows how little of the full image frame was taken up by the Moon in test images taken Sept. 8, 2005, by the High Resolution Imaging Science Experiment HiRISE camera on NASA Mars Reconnaissance Orbiter.
Guelpa, Valérian; Laurent, Guillaume J; Sandoz, Patrick; Zea, July Galeano; Clévy, Cédric
2014-03-12
This paper presents a visual measurement method able to sense 1D rigid body displacements with very high resolutions, large ranges and high processing rates. Sub-pixelic resolution is obtained thanks to a structured pattern placed on the target. The pattern is made of twin periodic grids with slightly different periods. The periodic frames are suited for Fourier-like phase calculations-leading to high resolution-while the period difference allows the removal of phase ambiguity and thus a high range-to-resolution ratio. The paper presents the measurement principle as well as the processing algorithms (source files are provided as supplementary materials). The theoretical and experimental performances are also discussed. The processing time is around 3 µs for a line of 780 pixels, which means that the measurement rate is mostly limited by the image acquisition frame rate. A 3-σ repeatability of 5 nm is experimentally demonstrated which has to be compared with the 168 µm measurement range.
High-performance software-only H.261 video compression on PC
NASA Astrophysics Data System (ADS)
Kasperovich, Leonid
1996-03-01
This paper describes an implementation of a software H.261 codec for PC, that takes an advantage of the fast computational algorithms for DCT-based video compression, which have been presented by the author at the February's 1995 SPIE/IS&T meeting. The motivation for developing the H.261 prototype system is to demonstrate a feasibility of real time software- only videoconferencing solution to operate across a wide range of network bandwidth, frame rate, and resolution of the input video. As the bandwidths of current network technology will be increased, the higher frame rate and resolution of video to be transmitted is allowed, that requires, in turn, a software codec to be able to compress pictures of CIF (352 X 288) resolution at up to 30 frame/sec. Running on Pentium 133 MHz PC the codec presented is capable to compress video in CIF format at 21 - 23 frame/sec. This result is comparable to the known hardware-based H.261 solutions, but it doesn't require any specific hardware. The methods to achieve high performance, the program optimization technique for Pentium microprocessor along with the performance profile, showing the actual contribution of the different encoding/decoding stages to the overall computational process, are presented.
Kazantsev, D.; Van Eyndhoven, G.; Lionheart, W. R. B.; Withers, P. J.; Dobson, K. J.; McDonald, S. A.; Atwood, R.; Lee, P. D.
2015-01-01
There are many cases where one needs to limit the X-ray dose, or the number of projections, or both, for high frame rate (fast) imaging. Normally, it improves temporal resolution but reduces the spatial resolution of the reconstructed data. Fortunately, the redundancy of information in the temporal domain can be employed to improve spatial resolution. In this paper, we propose a novel regularizer for iterative reconstruction of time-lapse computed tomography. The non-local penalty term is driven by the available prior information and employs all available temporal data to improve the spatial resolution of each individual time frame. A high-resolution prior image from the same or a different imaging modality is used to enhance edges which remain stationary throughout the acquisition time while dynamic features tend to be regularized spatially. Effective computational performance together with robust improvement in spatial and temporal resolution makes the proposed method a competitive tool to state-of-the-art techniques. PMID:25939621
Deep learning massively accelerates super-resolution localization microscopy.
Ouyang, Wei; Aristov, Andrey; Lelek, Mickaël; Hao, Xian; Zimmer, Christophe
2018-06-01
The speed of super-resolution microscopy methods based on single-molecule localization, for example, PALM and STORM, is limited by the need to record many thousands of frames with a small number of observed molecules in each. Here, we present ANNA-PALM, a computational strategy that uses artificial neural networks to reconstruct super-resolution views from sparse, rapidly acquired localization images and/or widefield images. Simulations and experimental imaging of microtubules, nuclear pores, and mitochondria show that high-quality, super-resolution images can be reconstructed from up to two orders of magnitude fewer frames than usually needed, without compromising spatial resolution. Super-resolution reconstructions are even possible from widefield images alone, though adding localization data improves image quality. We demonstrate super-resolution imaging of >1,000 fields of view containing >1,000 cells in ∼3 h, yielding an image spanning spatial scales from ∼20 nm to ∼2 mm. The drastic reduction in acquisition time and sample irradiation afforded by ANNA-PALM enables faster and gentler high-throughput and live-cell super-resolution imaging.
The Atlases of Vesta derived from Dawn Framing Camera images
NASA Astrophysics Data System (ADS)
Roatsch, T.; Kersten, E.; Matz, K.; Preusker, F.; Scholten, F.; Jaumann, R.; Raymond, C. A.; Russell, C. T.
2013-12-01
The Dawn Framing Camera acquired during its two HAMO (High Altitude Mapping Orbit) phases in 2011 and 2012 about 6,000 clear filter images with a resolution of about 60 m/pixel. We combined these images in a global ortho-rectified mosaic of Vesta (60 m/pixel resolution). Only very small areas near the northern pole were still in darkness and are missing in the mosaic. The Dawn Framing Camera also acquired about 10,000 high-resolution clear filter images (about 20 m/pixel) of Vesta during its Low Altitude Mapping Orbit (LAMO). Unfortunately, the northern part of Vesta was still in darkness during this phase, good illumination (incidence angle < 70°) was only available for 66.8 % of the surface [1]. We used the LAMO images to calculate another global mosaic of Vesta, this time with 20 m/pixel resolution. Both global mosaics were used to produce atlases of Vesta: a HAMO atlas with 15 tiles at a scale of 1:500,000 and a LAMO atlas with 30 tiles at a scale between 1:200,000 and 1:225,180. The nomenclature used in these atlases is based on names and places historically associated with the Roman goddess Vesta, and is compliant with the rules of the IAU. 65 names for geological features were already approved by the IAU, 39 additional names are currently under review. Selected examples of both atlases will be shown in this presentation. Reference: [1]Roatsch, Th., etal., High-resolution Vesta Low Altitude Mapping Orbit Atlas derived from Dawn Framing Camera images. Planetary and Space Science (2013), http://dx.doi.org/10.1016/j.pss.2013.06.024i
Coincidence electron/ion imaging with a fast frame camera
NASA Astrophysics Data System (ADS)
Li, Wen; Lee, Suk Kyoung; Lin, Yun Fei; Lingenfelter, Steven; Winney, Alexander; Fan, Lin
2015-05-01
A new time- and position- sensitive particle detection system based on a fast frame CMOS camera is developed for coincidence electron/ion imaging. The system is composed of three major components: a conventional microchannel plate (MCP)/phosphor screen electron/ion imager, a fast frame CMOS camera and a high-speed digitizer. The system collects the positional information of ions/electrons from a fast frame camera through real-time centroiding while the arrival times are obtained from the timing signal of MCPs processed by a high-speed digitizer. Multi-hit capability is achieved by correlating the intensity of electron/ion spots on each camera frame with the peak heights on the corresponding time-of-flight spectrum. Efficient computer algorithms are developed to process camera frames and digitizer traces in real-time at 1 kHz laser repetition rate. We demonstrate the capability of this system by detecting a momentum-matched co-fragments pair (methyl and iodine cations) produced from strong field dissociative double ionization of methyl iodide. We further show that a time resolution of 30 ps can be achieved when measuring electron TOF spectrum and this enables the new system to achieve a good energy resolution along the TOF axis.
Li, Yiming; Ishitsuka, Yuji; Hedde, Per Niklas; Nienhaus, G Ulrich
2013-06-25
In localization-based super-resolution microscopy, individual fluorescent markers are stochastically photoactivated and subsequently localized within a series of camera frames, yielding a final image with a resolution far beyond the diffraction limit. Yet, before localization can be performed, the subregions within the frames where the individual molecules are present have to be identified-oftentimes in the presence of high background. In this work, we address the importance of reliable molecule identification for the quality of the final reconstructed super-resolution image. We present a fast and robust algorithm (a-livePALM) that vastly improves the molecule detection efficiency while minimizing false assignments that can lead to image artifacts.
High-resolution wavefront reconstruction using the frozen flow hypothesis
NASA Astrophysics Data System (ADS)
Liu, Xuewen; Liang, Yonghui; Liu, Jin; Xu, Jieping
2017-10-01
This paper describes an approach to reconstructing wavefronts on finer grid using the frozen flow hypothesis (FFH), which exploits spatial and temporal correlations between consecutive wavefront sensor (WFS) frames. Under the assumption of FFH, slope data from WFS can be connected to a finer, composite slope grid using translation and down sampling, and elements in transformation matrices are determined by wind information. Frames of slopes are then combined and slopes on finer grid are reconstructed by solving a sparse, large-scale, ill-posed least squares problem. By using reconstructed finer slope data and adopting Fried geometry of WFS, high-resolution wavefronts are then reconstructed. The results show that this method is robust even with detector noise and wind information inaccuracy, and under bad seeing conditions, high-frequency information in wavefronts can be recovered more accurately compared with when correlations in WFS frames are ignored.
NASA Astrophysics Data System (ADS)
He, Qiang; Schultz, Richard R.; Chu, Chee-Hung Henry
2008-04-01
The concept surrounding super-resolution image reconstruction is to recover a highly-resolved image from a series of low-resolution images via between-frame subpixel image registration. In this paper, we propose a novel and efficient super-resolution algorithm, and then apply it to the reconstruction of real video data captured by a small Unmanned Aircraft System (UAS). Small UAS aircraft generally have a wingspan of less than four meters, so that these vehicles and their payloads can be buffeted by even light winds, resulting in potentially unstable video. This algorithm is based on a coarse-to-fine strategy, in which a coarsely super-resolved image sequence is first built from the original video data by image registration and bi-cubic interpolation between a fixed reference frame and every additional frame. It is well known that the median filter is robust to outliers. If we calculate pixel-wise medians in the coarsely super-resolved image sequence, we can restore a refined super-resolved image. The primary advantage is that this is a noniterative algorithm, unlike traditional approaches based on highly-computational iterative algorithms. Experimental results show that our coarse-to-fine super-resolution algorithm is not only robust, but also very efficient. In comparison with five well-known super-resolution algorithms, namely the robust super-resolution algorithm, bi-cubic interpolation, projection onto convex sets (POCS), the Papoulis-Gerchberg algorithm, and the iterated back projection algorithm, our proposed algorithm gives both strong efficiency and robustness, as well as good visual performance. This is particularly useful for the application of super-resolution to UAS surveillance video, where real-time processing is highly desired.
Chromatic Modulator for High Resolution CCD or APS Devices
NASA Technical Reports Server (NTRS)
Hartley, Frank T. (Inventor); Hull, Anthony B. (Inventor)
2003-01-01
A system for providing high-resolution color separation in electronic imaging. Comb drives controllably oscillate a red-green-blue (RGB) color strip filter system (or otherwise) over an electronic imaging system such as a charge-coupled device (CCD) or active pixel sensor (APS). The color filter is modulated over the imaging array at a rate three or more times the frame rate of the imaging array. In so doing, the underlying active imaging elements are then able to detect separate color-separated images, which are then combined to provide a color-accurate frame which is then recorded as the representation of the recorded image. High pixel resolution is maintained. Registration is obtained between the color strip filter and the underlying imaging array through the use of electrostatic comb drives in conjunction with a spring suspension system.
Robust video super-resolution with registration efficiency adaptation
NASA Astrophysics Data System (ADS)
Zhang, Xinfeng; Xiong, Ruiqin; Ma, Siwei; Zhang, Li; Gao, Wen
2010-07-01
Super-Resolution (SR) is a technique to construct a high-resolution (HR) frame by fusing a group of low-resolution (LR) frames describing the same scene. The effectiveness of the conventional super-resolution techniques, when applied on video sequences, strongly relies on the efficiency of motion alignment achieved by image registration. Unfortunately, such efficiency is limited by the motion complexity in the video and the capability of adopted motion model. In image regions with severe registration errors, annoying artifacts usually appear in the produced super-resolution video. This paper proposes a robust video super-resolution technique that adapts itself to the spatially-varying registration efficiency. The reliability of each reference pixel is measured by the corresponding registration error and incorporated into the optimization objective function of SR reconstruction. This makes the SR reconstruction highly immune to the registration errors, as outliers with higher registration errors are assigned lower weights in the objective function. In particular, we carefully design a mechanism to assign weights according to registration errors. The proposed superresolution scheme has been tested with various video sequences and experimental results clearly demonstrate the effectiveness of the proposed method.
Haider, Clifton R; Borisch, Eric A; Glockner, James F; Mostardi, Petrice M; Rossman, Phillip J; Young, Phillip M; Riederer, Stephen J
2010-10-01
High temporal and spatial resolution is desired in imaging of vascular abnormalities having short arterial-to-venous transit times. Methods that exploit temporal correlation to reduce the observed frame time demonstrate temporal blurring, obfuscating bolus dynamics. Previously, a Cartesian acquisition with projection reconstruction-like (CAPR) sampling method has been demonstrated for three-dimensional contrast-enhanced angiographic imaging of the lower legs using two-dimensional sensitivity-encoding acceleration and partial Fourier acceleration, providing 1mm isotropic resolution of the calves, with 4.9-sec frame time and 17.6-sec temporal footprint. In this work, the CAPR acquisition is further undersampled to provide a net acceleration approaching 40 by eliminating all view sharing. The tradeoff of frame time and temporal footprint in view sharing is presented and characterized in phantom experiments. It is shown that the resultant 4.9-sec acquisition time, three-dimensional images sets have sufficient spatial and temporal resolution to clearly portray arterial and venous phases of contrast passage. It is further hypothesized that these short temporal footprint sequences provide diagnostic quality images. This is tested and shown in a series of nine contrast-enhanced MR angiography patient studies performed with the new method.
Applying compressive sensing to TEM video: A substantial frame rate increase on any camera
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stevens, Andrew; Kovarik, Libor; Abellan, Patricia
One of the main limitations of imaging at high spatial and temporal resolution during in-situ transmission electron microscopy (TEM) experiments is the frame rate of the camera being used to image the dynamic process. While the recent development of direct detectors has provided the hardware to achieve frame rates approaching 0.1 ms, the cameras are expensive and must replace existing detectors. In this paper, we examine the use of coded aperture compressive sensing (CS) methods to increase the frame rate of any camera with simple, low-cost hardware modifications. The coded aperture approach allows multiple sub-frames to be coded and integratedmore » into a single camera frame during the acquisition process, and then extracted upon readout using statistical CS inversion. Here we describe the background of CS and statistical methods in depth and simulate the frame rates and efficiencies for in-situ TEM experiments. Depending on the resolution and signal/noise of the image, it should be possible to increase the speed of any camera by more than an order of magnitude using this approach.« less
Applying compressive sensing to TEM video: A substantial frame rate increase on any camera
Stevens, Andrew; Kovarik, Libor; Abellan, Patricia; ...
2015-08-13
One of the main limitations of imaging at high spatial and temporal resolution during in-situ transmission electron microscopy (TEM) experiments is the frame rate of the camera being used to image the dynamic process. While the recent development of direct detectors has provided the hardware to achieve frame rates approaching 0.1 ms, the cameras are expensive and must replace existing detectors. In this paper, we examine the use of coded aperture compressive sensing (CS) methods to increase the frame rate of any camera with simple, low-cost hardware modifications. The coded aperture approach allows multiple sub-frames to be coded and integratedmore » into a single camera frame during the acquisition process, and then extracted upon readout using statistical CS inversion. Here we describe the background of CS and statistical methods in depth and simulate the frame rates and efficiencies for in-situ TEM experiments. Depending on the resolution and signal/noise of the image, it should be possible to increase the speed of any camera by more than an order of magnitude using this approach.« less
Ultrahigh-speed X-ray imaging of hypervelocity projectiles
NASA Astrophysics Data System (ADS)
Miller, Stuart; Singh, Bipin; Cool, Steven; Entine, Gerald; Campbell, Larry; Bishel, Ron; Rushing, Rick; Nagarkar, Vivek V.
2011-08-01
High-speed X-ray imaging is an extremely important modality for healthcare, industrial, military and research applications such as medical computed tomography, non-destructive testing, imaging in-flight projectiles, characterizing exploding ordnance, and analyzing ballistic impacts. We report on the development of a modular, ultrahigh-speed, high-resolution digital X-ray imaging system with large active imaging area and microsecond time resolution, capable of acquiring at a rate of up to 150,000 frames per second. The system is based on a high-resolution, high-efficiency, and fast-decay scintillator screen optically coupled to an ultra-fast image-intensified CCD camera designed for ballistic impact studies and hypervelocity projectile imaging. A specially designed multi-anode, high-fluence X-ray source with 50 ns pulse duration provides a sequence of blur-free images of hypervelocity projectiles traveling at speeds exceeding 8 km/s (18,000 miles/h). This paper will discuss the design, performance, and high frame rate imaging capability of the system.
High Resolution, High Frame Rate Video Technology
NASA Technical Reports Server (NTRS)
1990-01-01
Papers and working group summaries presented at the High Resolution, High Frame Rate Video (HHV) Workshop are compiled. HHV system is intended for future use on the Space Shuttle and Space Station Freedom. The Workshop was held for the dual purpose of: (1) allowing potential scientific users to assess the utility of the proposed system for monitoring microgravity science experiments; and (2) letting technical experts from industry recommend improvements to the proposed near-term HHV system. The following topics are covered: (1) State of the art in the video system performance; (2) Development plan for the HHV system; (3) Advanced technology for image gathering, coding, and processing; (4) Data compression applied to HHV; (5) Data transmission networks; and (6) Results of the users' requirements survey conducted by NASA.
Texton-based super-resolution for achieving high spatiotemporal resolution in hybrid camera system
NASA Astrophysics Data System (ADS)
Kamimura, Kenji; Tsumura, Norimichi; Nakaguchi, Toshiya; Miyake, Yoichi
2010-05-01
Many super-resolution methods have been proposed to enhance the spatial resolution of images by using iteration and multiple input images. In a previous paper, we proposed the example-based super-resolution method to enhance an image through pixel-based texton substitution to reduce the computational cost. In this method, however, we only considered the enhancement of a texture image. In this study, we modified this texton substitution method for a hybrid camera to reduce the required bandwidth of a high-resolution video camera. We applied our algorithm to pairs of high- and low-spatiotemporal-resolution videos, which were synthesized to simulate a hybrid camera. The result showed that the fine detail of the low-resolution video can be reproduced compared with bicubic interpolation and the required bandwidth could be reduced to about 1/5 in a video camera. It was also shown that the peak signal-to-noise ratios (PSNRs) of the images improved by about 6 dB in a trained frame and by 1.0-1.5 dB in a test frame, as determined by comparison with the processed image using bicubic interpolation, and the average PSNRs were higher than those obtained by the well-known Freeman’s patch-based super-resolution method. Compared with that of the Freeman’s patch-based super-resolution method, the computational time of our method was reduced to almost 1/10.
3-D ultrasound volume reconstruction using the direct frame interpolation method.
Scheipers, Ulrich; Koptenko, Sergei; Remlinger, Rachel; Falco, Tony; Lachaine, Martin
2010-11-01
A new method for 3-D ultrasound volume reconstruction using tracked freehand 3-D ultrasound is proposed. The method is based on solving the forward volume reconstruction problem using direct interpolation of high-resolution ultrasound B-mode image frames. A series of ultrasound B-mode image frames (an image series) is acquired using the freehand scanning technique and position sensing via optical tracking equipment. The proposed algorithm creates additional intermediate image frames by directly interpolating between two or more adjacent image frames of the original image series. The target volume is filled using the original frames in combination with the additionally constructed frames. Compared with conventional volume reconstruction methods, no additional filling of empty voxels or holes within the volume is required, because the whole extent of the volume is defined by the arrangement of the original and the additionally constructed B-mode image frames. The proposed direct frame interpolation (DFI) method was tested on two different data sets acquired while scanning the head and neck region of different patients. The first data set consisted of eight B-mode 2-D frame sets acquired under optimal laboratory conditions. The second data set consisted of 73 image series acquired during a clinical study. Sample volumes were reconstructed for all 81 image series using the proposed DFI method with four different interpolation orders, as well as with the pixel nearest-neighbor method using three different interpolation neighborhoods. In addition, volumes based on a reduced number of image frames were reconstructed for comparison of the different methods' accuracy and robustness in reconstructing image data that lies between the original image frames. The DFI method is based on a forward approach making use of a priori information about the position and shape of the B-mode image frames (e.g., masking information) to optimize the reconstruction procedure and to reduce computation times and memory requirements. The method is straightforward, independent of additional input or parameters, and uses the high-resolution B-mode image frames instead of usually lower-resolution voxel information for interpolation. The DFI method can be considered as a valuable alternative to conventional 3-D ultrasound reconstruction methods based on pixel or voxel nearest-neighbor approaches, offering better quality and competitive reconstruction time.
Recent advances in a linear micromirror array for high-resolution projection
NASA Astrophysics Data System (ADS)
Picard, Francis; Doucet, Michel; Niall, Keith K.; Larouche, Carl; Savard, Maxime; Crisan, Silviu; Thibault, Simon; Jerominek, Hubert
2004-05-01
The visual displays of contemporary military flight simulators lack adequate definition to represent scenes in basic fast-jet fighter tasks. For example, air-to-air and air-to-ground targets are not projected with sufficient contrast and resolution for a pilot to perceive aspect, aspect rate and object detail at real world slant ranges. Simulator display geometries require the development of ultra-high resolution projectors with greater than 20 megapixel resolution at 60 Hz frame rate. A new micromirror device has been developed to address this requirement; it is able to modulate light intensity in an analog fashion with switching times shorter than 5 μs. When combined with a scanner, a laser and Schlieren optics, a linear array of these flexible micromirrors can display images composed of thousands of lines at a frame rate of 60 Hz. Recent results related to evaluation of this technology for high resolution projection are presented. Alternate operation modes for light modulation with flexible micromirrors are proposed. The related importance of controlling the residual micromirror curvature is discussed and results of experiments investigating the use of the deposition pressure to achieve such control are reported. Moreover, activities aiming at minimizing the micromirror response time and, so doing, maximizing the number of image columns per image frame are discussed. Finally, contrast measurement and estimate of the contrast limit achievable with the flexible micromirror technology are presented. All reported activities support the development of a fully addressable 2000-element micromirror array.
VIRTUAL FRAME BUFFER INTERFACE
NASA Technical Reports Server (NTRS)
Wolfe, T. L.
1994-01-01
Large image processing systems use multiple frame buffers with differing architectures and vendor supplied user interfaces. This variety of architectures and interfaces creates software development, maintenance, and portability problems for application programs. The Virtual Frame Buffer Interface program makes all frame buffers appear as a generic frame buffer with a specified set of characteristics, allowing programmers to write code which will run unmodified on all supported hardware. The Virtual Frame Buffer Interface converts generic commands to actual device commands. The virtual frame buffer consists of a definition of capabilities and FORTRAN subroutines that are called by application programs. The virtual frame buffer routines may be treated as subroutines, logical functions, or integer functions by the application program. Routines are included that allocate and manage hardware resources such as frame buffers, monitors, video switches, trackballs, tablets and joysticks; access image memory planes; and perform alphanumeric font or text generation. The subroutines for the various "real" frame buffers are in separate VAX/VMS shared libraries allowing modification, correction or enhancement of the virtual interface without affecting application programs. The Virtual Frame Buffer Interface program was developed in FORTRAN 77 for a DEC VAX 11/780 or a DEC VAX 11/750 under VMS 4.X. It supports ADAGE IK3000, DEANZA IP8500, Low Resolution RAMTEK 9460, and High Resolution RAMTEK 9460 Frame Buffers. It has a central memory requirement of approximately 150K. This program was developed in 1985.
A framed, 16-image Kirkpatrick–Baez x-ray microscope
Marshall, F. J.; Bahr, R. E.; Goncharov, V. N.; ...
2017-09-08
A 16-image Kirkpatrick–Baez (KB)–type x-ray microscope consisting of compact KB mirrors has been assembled for the first time with mirrors aligned to allow it to be coupled to a high-speed framing camera. The high-speed framing camera has four independently gated strips whose emission sampling interval is ~30 ps. Images are arranged four to a strip with ~60-ps temporal spacing between frames on a strip. By spacing the timing of the strips, a frame spacing of ~15 ps is achieved. A framed resolution of ~6-um is achieved with this combination in a 400-um region of laser–plasma x-ray emission in the 2-more » to 8-keV energy range. A principal use of the microscope is to measure the evolution of the implosion stagnation region of cryogenic DT target implosions on the University of Rochester’s OMEGA Laser System. The unprecedented time and spatial resolution achieved with this framed, multi-image KB microscope have made it possible to accurately determine the cryogenic implosion core emission size and shape at the peak of stagnation. In conclusion, these core size measurements, taken in combination with those of ion temperature, neutron-production temporal width, and neutron yield allow for inference of core pressures, currently exceeding 50 GBar in OMEGA cryogenic target implosions.« less
A framed, 16-image Kirkpatrick–Baez x-ray microscope
DOE Office of Scientific and Technical Information (OSTI.GOV)
Marshall, F. J.; Bahr, R. E.; Goncharov, V. N.
A 16-image Kirkpatrick–Baez (KB)–type x-ray microscope consisting of compact KB mirrors has been assembled for the first time with mirrors aligned to allow it to be coupled to a high-speed framing camera. The high-speed framing camera has four independently gated strips whose emission sampling interval is ~30 ps. Images are arranged four to a strip with ~60-ps temporal spacing between frames on a strip. By spacing the timing of the strips, a frame spacing of ~15 ps is achieved. A framed resolution of ~6-um is achieved with this combination in a 400-um region of laser–plasma x-ray emission in the 2-more » to 8-keV energy range. A principal use of the microscope is to measure the evolution of the implosion stagnation region of cryogenic DT target implosions on the University of Rochester’s OMEGA Laser System. The unprecedented time and spatial resolution achieved with this framed, multi-image KB microscope have made it possible to accurately determine the cryogenic implosion core emission size and shape at the peak of stagnation. In conclusion, these core size measurements, taken in combination with those of ion temperature, neutron-production temporal width, and neutron yield allow for inference of core pressures, currently exceeding 50 GBar in OMEGA cryogenic target implosions.« less
NASA Astrophysics Data System (ADS)
Leonard, E. J.; Pappalardo, R. T.; Yin, A.; Prockter, L. M.; Patthoff, D. A.
2014-12-01
The Galileo Solid State Imager (SSI) recorded nine very high-resolution frames (8 at 12 m/pixel and 1 at 6 m/pixel) during the E12 flyby of Europa in Dec. 1997. To understand the implications for the small-scale structure and evolution of Europa, we mosaicked these frames (observations 12ESMOTTLE01 and 02, incidence ≈18°, emission ≈77°) into their regional context (part of observation 11ESREGMAP01, 220 m/pixel, incidence ≈74°, emission ≈23°), despite their very different viewing and lighting conditions. We created a map of geological units based on morphology, structure, and albedo along with stereoscopic images where the frames overlapped. The highly diverse units range from: high albedo sub-parallel ridge and grooved terrain; to variegated-albedo hummocky terrain; to low albedo and relatively smooth terrain. We classified and analyzed the diverse units solely based on the high-resolution image mosaic, prior to comparison to the context image, to obtain an in-depth look at possible surface evolution and underlying formational processes. We infer that some of these units represent different stages and forms of resurfacing, including cryovolcanic and tectonic resurfacing. However, significant morphological variation among units in the region indicates that there are different degrees of resurfacing at work. We have created candidate morphological sequences that provide insight into the conversion of ridged plains to chaotic terrain—generally, a process of subduing formerly sharp features through tectonic modification and/or cryovolcanism. When the map of the high-resolution area is compared to the regional context, features that appear to be one unit at regional resolution are comprised of several distinct units at high resolution, and features that appear to be smooth in the context image are found to show distinct textures. Moreover, in the context image, transitions from ridged units to disrupted units appear to be gradual; however the high-resolution image reveals them to be abrupt, suggesting tectonic control of these boundaries. These discrepancies could have important implications for a future landed exploration.
Creation of a Multiresolution and Multiaccuracy Dtm: Problems and Solutions for Heli-Dem Case Study
NASA Astrophysics Data System (ADS)
Biagi, L.; Carcano, L.; Lucchese, A.; Negretti, M.
2013-01-01
The work is part of "HELI-DEM" (HELvetia-Italy Digital Elevation Model) project, funded by the European Regional Development Fund within the Italy-Switzerland cooperation program. The aim of the project is the creation of a unique DTM for the alpine and subalpine area between Italy (Piedmont, Lombardy) and Switzerland (Ticino and Grisons Cantons); at present, different DTMs, that are in different reference frames and have been obtained with different technologies, accuracies, and resolutions, have been acquired. The final DTM should be correctly georeferenced and produced validating and integrating the data that are available for the project. DTMs are fundamental in hydrogeological studies, especially in alpine areas where hydrogeological risks may exist. Moreover, when an event, like for example a landslide, happens at the border between countries, a unique and integrated DTM which covers the interest area is useful to analyze the scenario. In this sense, HELI-DEM project is helpful. To perform analyses along the borders between countries, transnational geographic information is needed: a transnational DTM can be obtained by merging regional low resolution DTMs. Moreover high resolution local DTMs should be used where they are available. To be merged, low and high resolution DTMs should be in the same three dimensional reference frame, should not present biases and should be consistent in the overlapping areas. Cross-validation between the different DTMs is therefore needed. Two different problems should be solved: the merging of regional, partly overlapping low and medium resolution DTMs into a unique low/medium resolution DTM and the merging with other local high resolution/high accuracy height data. This paper discusses the preliminary processing of the data for the fusion of low and high resolution DTMs in a study-case area within the Lombardy region: Valtellina valley. In this region the Lombardy regional low resolution DTM is available, with a horizontal resolution of 20 meters; in addition a LiDAR DTM with a horizontal resolution of 1 meter, which covers only the main hydrographic basins, is also available. The two DTMs have been transformed into the same reference frame. The cross-validation of the two datasets has been performed comparing the low resolution DTM with the local high resolution DTM. Then, where significant differences are present, GPS survey have been used as external validation. The results are presented. Moreover, a possible strategy for the future fusion of the data, is shortly summarized at the end of the paper.
40 MHz high-frequency ultrafast ultrasound imaging.
Huang, Chih-Chung; Chen, Pei-Yu; Peng, Po-Hsun; Lee, Po-Yang
2017-06-01
Ultrafast high-frame-rate ultrasound imaging based on coherent-plane-wave compounding has been developed for many biomedical applications. Most coherent-plane-wave compounding systems typically operate at 3-15 MHz, and the image resolution for this frequency range is not sufficient for visualizing microstructure tissues. Therefore, the purpose of this study was to implement a high-frequency ultrafast ultrasound imaging operating at 40 MHz. The plane-wave compounding imaging and conventional multifocus B-mode imaging were performed using the Field II toolbox of MATLAB in simulation study. In experiments, plane-wave compounding images were obtained from a 256 channel ultrasound research platform with a 40 MHz array transducer. All images were produced by point-spread functions and cyst phantoms. The in vivo experiment was performed from zebrafish. Since high-frequency ultrasound exhibits a lower penetration, chirp excitation was applied to increase the imaging depth in simulation. The simulation results showed that a lateral resolution of up to 66.93 μm and a contrast of up to 56.41 dB were achieved when using 75-angles plane waves in compounding imaging. The experimental results showed that a lateral resolution of up to 74.83 μm and a contrast of up to 44.62 dB were achieved when using 75-angles plane waves in compounding imaging. The dead zone and compounding noise are about 1.2 mm and 2.0 mm in depth for experimental compounding imaging, respectively. The structure of zebrafish heart was observed clearly using plane-wave compounding imaging. The use of fewer than 23 angles for compounding allowed a frame rate higher than 1000 frames per second. However, the compounding imaging exhibits a similar lateral resolution of about 72 μm as the angle of plane wave is higher than 10 angles. This study shows the highest operational frequency for ultrafast high-frame-rate ultrasound imaging. © 2017 American Association of Physicists in Medicine.
Guelpa, Valérian; Laurent, Guillaume J.; Sandoz, Patrick; Zea, July Galeano; Clévy, Cédric
2014-01-01
This paper presents a visual measurement method able to sense 1D rigid body displacements with very high resolutions, large ranges and high processing rates. Sub-pixelic resolution is obtained thanks to a structured pattern placed on the target. The pattern is made of twin periodic grids with slightly different periods. The periodic frames are suited for Fourier-like phase calculations—leading to high resolution—while the period difference allows the removal of phase ambiguity and thus a high range-to-resolution ratio. The paper presents the measurement principle as well as the processing algorithms (source files are provided as supplementary materials). The theoretical and experimental performances are also discussed. The processing time is around 3 μs for a line of 780 pixels, which means that the measurement rate is mostly limited by the image acquisition frame rate. A 3-σ repeatability of 5 nm is experimentally demonstrated which has to be compared with the 168 μm measurement range. PMID:24625736
High resolution wavenumber analysis for investigation of arterial pulse wave propagation
NASA Astrophysics Data System (ADS)
Hasegawa, Hideyuki; Sato, Masakazu; Irie, Takasuke
2016-07-01
The propagation of the pulse wave along the artery is relatively fast (several m/s), and a high-temporal resolution is required to measure pulse wave velocity (PWV) in a regional segment of the artery. High-frame-rate ultrasound enables the measurement of the regional PWV. In analyses of wave propagation phenomena, the direction and propagation speed are generally identified in the frequency-wavenumber space using the two-dimensional Fourier transform. However, the wavelength of the pulse wave is very long (1 m at a propagation velocity of 10 m/s and a temporal frequency of 10 Hz) compared with a typical lateral field of view of 40 mm in ultrasound imaging. Therefore, PWV cannot be identified in the frequency-wavenumber space owing to the low resolution of the two-dimensional Fourier transform. In the present study, PWV was visualized in the wavenumber domain using phases of arterial wall acceleration waveforms measured by high-frame-rate ultrasound.
NASA Astrophysics Data System (ADS)
Megens, Remco T. A.; Reitsma, Sietze; Prinzen, Lenneke; Oude Egbrink, Mirjam G. A.; Engels, Wim; Leenders, Peter J. A.; Brunenberg, Ellen J. L.; Reesink, Koen D.; Janssen, Ben J. A.; Ter Haar Romeny, Bart M.; Slaaf, Dick W.; van Zandvoort, Marc A. M. J.
2010-01-01
In vivo (molecular) imaging of the vessel wall of large arteries at subcellular resolution is crucial for unraveling vascular pathophysiology. We previously showed the applicability of two-photon laser scanning microscopy (TPLSM) in mounted arteries ex vivo. However, in vivo TPLSM has thus far suffered from in-frame and between-frame motion artifacts due to arterial movement with cardiac and respiratory activity. Now, motion artifacts are suppressed by accelerated image acquisition triggered on cardiac and respiratory activity. In vivo TPLSM is performed on rat renal and mouse carotid arteries, both surgically exposed and labeled fluorescently (cell nuclei, elastin, and collagen). The use of short acquisition times consistently limit in-frame motion artifacts. Additionally, triggered imaging reduces between-frame artifacts. Indeed, structures in the vessel wall (cell nuclei, elastic laminae) can be imaged at subcellular resolution. In mechanically damaged carotid arteries, even the subendothelial collagen sheet (~1 μm) is visualized using collagen-targeted quantum dots. We demonstrate stable in vivo imaging of large arteries at subcellular resolution using TPLSM triggered on cardiac and respiratory cycles. This creates great opportunities for studying (diseased) arteries in vivo or immediate validation of in vivo molecular imaging techniques such as magnetic resonance imaging (MRI), ultrasound, and positron emission tomography (PET).
2005-02-01
2004. 3. Pesavento , A. and A. Lorenz. Real time stain imaging and in vivo applications in prostate cancer, in IEEE Ultrasonics Symposium. 2001. 4...Symposium. 2000. 6. Pesavento A, L.A., Ermert H, Sommerfeld H, Garcia-Schurmann M, Senge Th, Philippou S. Frame-to-frame statistics of real-time strain
Image resolution enhancement via image restoration using neural network
NASA Astrophysics Data System (ADS)
Zhang, Shuangteng; Lu, Yihong
2011-04-01
Image super-resolution aims to obtain a high-quality image at a resolution that is higher than that of the original coarse one. This paper presents a new neural network-based method for image super-resolution. In this technique, the super-resolution is considered as an inverse problem. An observation model that closely follows the physical image acquisition process is established to solve the problem. Based on this model, a cost function is created and minimized by a Hopfield neural network to produce high-resolution images from the corresponding low-resolution ones. Not like some other single frame super-resolution techniques, this technique takes into consideration point spread function blurring as well as additive noise and therefore generates high-resolution images with more preserved or restored image details. Experimental results demonstrate that the high-resolution images obtained by this technique have a very high quality in terms of PSNR and visually look more pleasant.
NASA Astrophysics Data System (ADS)
Tremsin, A. S.; Vallerga, J. V.; McPhate, J. B.; Siegmund, O. H. W.
2015-07-01
Many high resolution event counting devices process one event at a time and cannot register simultaneous events. In this article a frame-based readout event counting detector consisting of a pair of Microchannel Plates and a quad Timepix readout is described. More than 104 simultaneous events can be detected with a spatial resolution of 55 μm, while >103 simultaneous events can be detected with <10 μm spatial resolution when event centroiding is implemented. The fast readout electronics is capable of processing >1200 frames/sec, while the global count rate of the detector can exceed 5×108 particles/s when no timing information on every particle is required. For the first generation Timepix readout, the timing resolution is limited by the Timepix clock to 10-20 ns. Optimization of the MCP gain, rear field voltage and Timepix threshold levels are crucial for the device performance and that is the main subject of this article. These devices can be very attractive for applications where the photon/electron/ion/neutron counting with high spatial and temporal resolution is required, such as energy resolved neutron imaging, Time of Flight experiments in lidar applications, experiments on photoelectron spectroscopy and many others.
Data compression techniques applied to high resolution high frame rate video technology
NASA Technical Reports Server (NTRS)
Hartz, William G.; Alexovich, Robert E.; Neustadter, Marc S.
1989-01-01
An investigation is presented of video data compression applied to microgravity space experiments using High Resolution High Frame Rate Video Technology (HHVT). An extensive survey of methods of video data compression, described in the open literature, was conducted. The survey examines compression methods employing digital computing. The results of the survey are presented. They include a description of each method and assessment of image degradation and video data parameters. An assessment is made of present and near term future technology for implementation of video data compression in high speed imaging system. Results of the assessment are discussed and summarized. The results of a study of a baseline HHVT video system, and approaches for implementation of video data compression, are presented. Case studies of three microgravity experiments are presented and specific compression techniques and implementations are recommended.
Spatial resampling of IDR frames for low bitrate video coding with HEVC
NASA Astrophysics Data System (ADS)
Hosking, Brett; Agrafiotis, Dimitris; Bull, David; Easton, Nick
2015-03-01
As the demand for higher quality and higher resolution video increases, many applications fail to meet this demand due to low bandwidth restrictions. One factor contributing to this problem is the high bitrate requirement of the intra-coded Instantaneous Decoding Refresh (IDR) frames featuring in all video coding standards. Frequent coding of IDR frames is essential for error resilience in order to prevent the occurrence of error propagation. However, as each one consumes a huge portion of the available bitrate, the quality of future coded frames is hindered by high levels of compression. This work presents a new technique, known as Spatial Resampling of IDR Frames (SRIF), and shows how it can increase the rate distortion performance by providing a higher and more consistent level of video quality at low bitrates.
MPCM: a hardware coder for super slow motion video sequences
NASA Astrophysics Data System (ADS)
Alcocer, Estefanía; López-Granado, Otoniel; Gutierrez, Roberto; Malumbres, Manuel P.
2013-12-01
In the last decade, the improvements in VLSI levels and image sensor technologies have led to a frenetic rush to provide image sensors with higher resolutions and faster frame rates. As a result, video devices were designed to capture real-time video at high-resolution formats with frame rates reaching 1,000 fps and beyond. These ultrahigh-speed video cameras are widely used in scientific and industrial applications, such as car crash tests, combustion research, materials research and testing, fluid dynamics, and flow visualization that demand real-time video capturing at extremely high frame rates with high-definition formats. Therefore, data storage capability, communication bandwidth, processing time, and power consumption are critical parameters that should be carefully considered in their design. In this paper, we propose a fast FPGA implementation of a simple codec called modulo-pulse code modulation (MPCM) which is able to reduce the bandwidth requirements up to 1.7 times at the same image quality when compared with PCM coding. This allows current high-speed cameras to capture in a continuous manner through a 40-Gbit Ethernet point-to-point access.
A video wireless capsule endoscopy system powered wirelessly: design, analysis and experiment
NASA Astrophysics Data System (ADS)
Pan, Guobing; Xin, Wenhui; Yan, Guozheng; Chen, Jiaoliao
2011-06-01
Wireless capsule endoscopy (WCE), as a relatively new technology, has brought about a revolution in the diagnosis of gastrointestinal (GI) tract diseases. However, the existing WCE systems are not widely applied in clinic because of the low frame rate and low image resolution. A video WCE system based on a wireless power supply is developed in this paper. This WCE system consists of a video capsule endoscope (CE), a wireless power transmission device, a receiving box and an image processing station. Powered wirelessly, the video CE has the abilities of imaging the GI tract and transmitting the images wirelessly at a frame rate of 30 frames per second (f/s). A mathematical prototype was built to analyze the power transmission system, and some experiments were performed to test the capability of energy transferring. The results showed that the wireless electric power supply system had the ability to transfer more than 136 mW power, which was enough for the working of a video CE. In in vitro experiments, the video CE produced clear images of the small intestine of a pig with the resolution of 320 × 240, and transmitted NTSC format video outside the body. Because of the wireless power supply, the video WCE system with high frame rate and high resolution becomes feasible, and provides a novel solution for the diagnosis of the GI tract in clinic.
All-passive pixel super-resolution of time-stretch imaging
Chan, Antony C. S.; Ng, Ho-Cheung; Bogaraju, Sharat C. V.; So, Hayden K. H.; Lam, Edmund Y.; Tsia, Kevin K.
2017-01-01
Based on image encoding in a serial-temporal format, optical time-stretch imaging entails a stringent requirement of state-of-the-art fast data acquisition unit in order to preserve high image resolution at an ultrahigh frame rate — hampering the widespread utilities of such technology. Here, we propose a pixel super-resolution (pixel-SR) technique tailored for time-stretch imaging that preserves pixel resolution at a relaxed sampling rate. It harnesses the subpixel shifts between image frames inherently introduced by asynchronous digital sampling of the continuous time-stretch imaging process. Precise pixel registration is thus accomplished without any active opto-mechanical subpixel-shift control or other additional hardware. Here, we present the experimental pixel-SR image reconstruction pipeline that restores high-resolution time-stretch images of microparticles and biological cells (phytoplankton) at a relaxed sampling rate (≈2–5 GSa/s)—more than four times lower than the originally required readout rate (20 GSa/s) — is thus effective for high-throughput label-free, morphology-based cellular classification down to single-cell precision. Upon integration with the high-throughput image processing technology, this pixel-SR time-stretch imaging technique represents a cost-effective and practical solution for large scale cell-based phenotypic screening in biomedical diagnosis and machine vision for quality control in manufacturing. PMID:28303936
NASA Astrophysics Data System (ADS)
Paudel, Hari P.; Jung, Yookyung; Raphael, Anthony; Alt, Clemens; Wu, Juwell; Runnels, Judith; Lin, Charles P.
2018-02-01
The present standard of blood cell analysis is an invasive procedure requiring the extraction of patient's blood, followed by ex-vivo analysis using a flow cytometer or a hemocytometer. We are developing a noninvasive optical technique that alleviates the need for blood extraction. For in-vivo blood analysis we need a high speed, high resolution and high contrast label-free imaging technique. In this proceeding report, we reported a label-free method based on differential epi-detection of forward scattered light, a method inspired by Jerome Mertz's oblique back-illumination microscopy (OBM) (Ford et al, Nat. Meth. 9(12) 2012). The differential epi-detection of forward light gives phase contrast image at diffraction-limited resolution. Unlike reflection confocal microscopy (RCM), which detects only sharp refractive index variation and suffers from speckle noise, this technique is suitable for detection of subtle variation of refractive index in biological tissue and it provides the shape and the size of cells. A custom built high speed electronic detection circuit board produces a real-time differential signal which yields image contrast based on phase gradient in the sample. We recorded blood flow in-vivo at 17.2k lines per second in line scan mode, or 30 frames per second (full frame), or 120 frame per second (quarter frame) in frame scan mode. The image contrast and speed of line scan data recording show the potential of the system for noninvasive blood cell analysis.
High speed, real-time, camera bandwidth converter
Bower, Dan E; Bloom, David A; Curry, James R
2014-10-21
Image data from a CMOS sensor with 10 bit resolution is reformatted in real time to allow the data to stream through communications equipment that is designed to transport data with 8 bit resolution. The incoming image data has 10 bit resolution. The communication equipment can transport image data with 8 bit resolution. Image data with 10 bit resolution is transmitted in real-time, without a frame delay, through the communication equipment by reformatting the image data.
Multisensor data fusion across time and space
NASA Astrophysics Data System (ADS)
Villeneuve, Pierre V.; Beaven, Scott G.; Reed, Robert A.
2014-06-01
Field measurement campaigns typically deploy numerous sensors having different sampling characteristics for spatial, temporal, and spectral domains. Data analysis and exploitation is made more difficult and time consuming as the sample data grids between sensors do not align. This report summarizes our recent effort to demonstrate feasibility of a processing chain capable of "fusing" image data from multiple independent and asynchronous sensors into a form amenable to analysis and exploitation using commercially-available tools. Two important technical issues were addressed in this work: 1) Image spatial registration onto a common pixel grid, 2) Image temporal interpolation onto a common time base. The first step leverages existing image matching and registration algorithms. The second step relies upon a new and innovative use of optical flow algorithms to perform accurate temporal upsampling of slower frame rate imagery. Optical flow field vectors were first derived from high-frame rate, high-resolution imagery, and then finally used as a basis for temporal upsampling of the slower frame rate sensor's imagery. Optical flow field values are computed using a multi-scale image pyramid, thus allowing for more extreme object motion. This involves preprocessing imagery to varying resolution scales and initializing new vector flow estimates using that from the previous coarser-resolution image. Overall performance of this processing chain is demonstrated using sample data involving complex too motion observed by multiple sensors mounted to the same base. Multiple sensors were included, including a high-speed visible camera, up to a coarser resolution LWIR camera.
Ultra-fast framing camera tube
Kalibjian, Ralph
1981-01-01
An electronic framing camera tube features focal plane image dissection and synchronized restoration of the dissected electron line images to form two-dimensional framed images. Ultra-fast framing is performed by first streaking a two-dimensional electron image across a narrow slit, thereby dissecting the two-dimensional electron image into sequential electron line images. The dissected electron line images are then restored into a framed image by a restorer deflector operated synchronously with the dissector deflector. The number of framed images on the tube's viewing screen is equal to the number of dissecting slits in the tube. The distinguishing features of this ultra-fast framing camera tube are the focal plane dissecting slits, and the synchronously-operated restorer deflector which restores the dissected electron line images into a two-dimensional framed image. The framing camera tube can produce image frames having high spatial resolution of optical events in the sub-100 picosecond range.
Anti-translational research: from the bedside back to the bench for reflectance confocal microscopy
NASA Astrophysics Data System (ADS)
Gareau, Daniel
2014-03-01
The reflectance confocal microscope has made translational progress in dermatology. 0.5 micrometer lateral resolution, 0.75mm field-of-view and excellent temporal resolution at ~15 frames/second serve the VivaScope well in the clinic, but it may be overlooked in basic research. This work reviews high spatiotemporal confocal microscopy and presents images acquired of various samples: zebra fish embryo where melanocytes with excellent contrast overly the spinal column, chicken embryo, where myocardium is seen moving at 15 frames/ second, calcium spikes in dendrites (fluorescence mode) just beyond the temporal resolution, and human skin where blood cells race through the artereovenous microvasculature. For an introduction to confocal microscopy, see: http://dangareau.net.s69818.gridserver.com/science/confocal-microscopy
High-Frame-Rate Speckle-Tracking Echocardiography.
Joos, Philippe; Poree, Jonathan; Liebgott, Herve; Vray, Didier; Baudet, Mathilde; Faurie, Julia; Tournoux, Francois; Cloutier, Guy; Nicolas, Barbara; Garcia, Damien; Baudet, Mathilde; Tournoux, Francois; Joos, Philippe; Poree, Jonathan; Cloutier, Guy; Liebgott, Herve; Faurie, Julia; Vray, Didier; Nicolas, Barbara; Garcia, Damien
2018-05-01
Conventional echocardiography is the leading modality for noninvasive cardiac imaging. It has been recently illustrated that high-frame-rate echocardiography using diverging waves could improve cardiac assessment. The spatial resolution and contrast associated with this method are commonly improved by coherent compounding of steered beams. However, owing to fast tissue velocities in the myocardium, the summation process of successive diverging waves can lead to destructive interferences if motion compensation (MoCo) is not considered. Coherent compounding methods based on MoCo have demonstrated their potential to provide high-contrast B-mode cardiac images. Ultrafast speckle-tracking echocardiography (STE) based on common speckle-tracking algorithms could substantially benefit from this original approach. In this paper, we applied STE on high-frame-rate B-mode images obtained with a specific MoCo technique to quantify the 2-D motion and tissue velocities of the left ventricle. The method was first validated in vitro and then evaluated in vivo in the four-chamber view of 10 volunteers. High-contrast high-resolution B-mode images were constructed at 500 frames/s. The sequences were generated with a Verasonics scanner and a 2.5-MHz phased array. The 2-D motion was estimated with standard cross correlation combined with three different subpixel adjustment techniques. The estimated in vitro velocity vectors derived from STE were consistent with the expected values, with normalized errors ranging from 4% to 12% in the radial direction and from 10% to 20% in the cross-range direction. Global longitudinal strain of the left ventricle was also obtained from STE in 10 subjects and compared to the results provided by a clinical scanner: group means were not statistically different ( value = 0.33). The in vitro and in vivo results showed that MoCo enables preservation of the myocardial speckles and in turn allows high-frame-rate STE.
An interferometer for high-resolution optical surveillance from geostationary orbit
NASA Astrophysics Data System (ADS)
Bonino, L.; Bresciani, F.; Piasini, G.; Flebus, C.; Lecat, J.-H.; Roose, S.; Pisani, M.; Cabral, A.; Rebordão, J.; Proença, C.; Costal, J.; Lima, P. U.; Loix, N.; Musso, F.
2017-11-01
The activities described in this paper have been developed in the frame of the EUCLID CEPA 9 RTP 9.9 "High Resolution Optical Satellite Sensor" project of the WEAO Research Cell. They have been focused on the definition of an interferometric instrument optimised for the high-resolution optical surveillance from geostationary orbit (GEO) by means of the synthetic aperture technique, and on the definition and development of the related enabling technologies. In this paper we describe the industrial team, the selected mission specifications and overview of the whole design and manufacturing activities performed.
Innovative Video Diagnostic Equipment for Material Science
NASA Technical Reports Server (NTRS)
Capuano, G.; Titomanlio, D.; Soellner, W.; Seidel, A.
2012-01-01
Materials science experiments under microgravity increasingly rely on advanced optical systems to determine the physical properties of the samples under investigation. This includes video systems with high spatial and temporal resolution. The acquisition, handling, storage and transmission to ground of the resulting video data are very challenging. Since the available downlink data rate is limited, the capability to compress the video data significantly without compromising the data quality is essential. We report on the development of a Digital Video System (DVS) for EML (Electro Magnetic Levitator) which provides real-time video acquisition, high compression using advanced Wavelet algorithms, storage and transmission of a continuous flow of video with different characteristics in terms of image dimensions and frame rates. The DVS is able to operate with the latest generation of high-performance cameras acquiring high resolution video images up to 4Mpixels@60 fps or high frame rate video images up to about 1000 fps@512x512pixels.
Celestial Reference Frames at Multiple Radio Wavelengths
NASA Technical Reports Server (NTRS)
Jacobs, Christopher S.
2012-01-01
In 1997 the IAU adopted the International Celestial Reference Frame (ICRF) built from S/X VLBI data. In response to IAU resolutions encouraging the extension of the ICRF to additional frequency bands, VLBI frames have been made at 24, 32, and 43 gigahertz. Meanwhile, the 8.4 gigahertz work has been greatly improved with the 2009 release of the ICRF-2. This paper discusses the motivations for extending the ICRF to these higher radio bands. Results to date will be summarized including evidence that the high frequency frames are rapidly approaching the accuracy of the 8.4 gigahertz ICRF-2. We discuss current limiting errors and prospects for the future accuracy of radio reference frames. We note that comparison of multiple radio frames is characterizing the frequency dependent systematic noise floor from extended source morphology and core shift. Finally, given Gaia's potential for high accuracy optical astrometry, we have simulated the precision of a radio-optical frame tie to be approximately10-15 microarcseconds ((1-sigma) (1-standard deviation), per component).
Solid state replacement of rotating mirror cameras
NASA Astrophysics Data System (ADS)
Frank, Alan M.; Bartolick, Joseph M.
2007-01-01
Rotating mirror cameras have been the mainstay of mega-frame per second imaging for decades. There is still no electronic camera that can match a film based rotary mirror camera for the combination of frame count, speed, resolution and dynamic range. The rotary mirror cameras are predominantly used in the range of 0.1 to 100 micro-seconds per frame, for 25 to more than a hundred frames. Electron tube gated cameras dominate the sub microsecond regime but are frame count limited. Video cameras are pushing into the microsecond regime but are resolution limited by the high data rates. An all solid state architecture, dubbed 'In-situ Storage Image Sensor' or 'ISIS', by Prof. Goji Etoh has made its first appearance into the market and its evaluation is discussed. Recent work at Lawrence Livermore National Laboratory has concentrated both on evaluation of the presently available technologies and exploring the capabilities of the ISIS architecture. It is clear though there is presently no single chip camera that can simultaneously match the rotary mirror cameras, the ISIS architecture has the potential to approach their performance.
Requirements on high resolution detectors
DOE Office of Scientific and Technical Information (OSTI.GOV)
Koch, A.
For a number of microtomography applications X-ray detectors with a spatial resolution of 1 {mu}m are required. This high spatial resolution will influence and degrade other parameters of secondary importance like detective quantum efficiency (DQE), dynamic range, linearity and frame rate. This note summarizes the most important arguments, for and against those detector systems which could be considered. This article discusses the mutual dependencies between the various figures which characterize a detector, and tries to give some ideas on how to proceed in order to improve present technology.
Tsai, Tsung-Han; Potsaid, Benjamin; Tao, Yuankai K; Jayaraman, Vijaysekhar; Jiang, James; Heim, Peter J S; Kraus, Martin F; Zhou, Chao; Hornegger, Joachim; Mashimo, Hiroshi; Cable, Alex E; Fujimoto, James G
2013-07-01
We developed a micromotor based miniature catheter with an outer diameter of 3.2 mm for ultrahigh speed endoscopic swept source optical coherence tomography (OCT) using a vertical cavity surface-emitting laser (VCSEL) at a 1 MHz axial scan rate. The micromotor can rotate a micro-prism at several hundred frames per second with less than 5 V drive voltage to provide fast and stable scanning, which is not sensitive to the bending of the catheter. The side-viewing probe can be pulled back to acquire a three-dimensional (3D) data set covering a large area on the specimen. The VCSEL provides a high axial scan rate to support dense sampling under high frame rate operation. Using a high speed data acquisition system, in vivo 3D-OCT imaging in the rabbit GI tract and ex vivo imaging of a human colon specimen with 8 μm axial resolution, 8 μm lateral resolution and 1.2 mm depth range in tissue at a frame rate of 400 fps was demonstrated.
Tsai, Tsung-Han; Potsaid, Benjamin; Tao, Yuankai K.; Jayaraman, Vijaysekhar; Jiang, James; Heim, Peter J. S.; Kraus, Martin F.; Zhou, Chao; Hornegger, Joachim; Mashimo, Hiroshi; Cable, Alex E.; Fujimoto, James G.
2013-01-01
We developed a micromotor based miniature catheter with an outer diameter of 3.2 mm for ultrahigh speed endoscopic swept source optical coherence tomography (OCT) using a vertical cavity surface-emitting laser (VCSEL) at a 1 MHz axial scan rate. The micromotor can rotate a micro-prism at several hundred frames per second with less than 5 V drive voltage to provide fast and stable scanning, which is not sensitive to the bending of the catheter. The side-viewing probe can be pulled back to acquire a three-dimensional (3D) data set covering a large area on the specimen. The VCSEL provides a high axial scan rate to support dense sampling under high frame rate operation. Using a high speed data acquisition system, in vivo 3D-OCT imaging in the rabbit GI tract and ex vivo imaging of a human colon specimen with 8 μm axial resolution, 8 μm lateral resolution and 1.2 mm depth range in tissue at a frame rate of 400 fps was demonstrated. PMID:23847737
NASA Technical Reports Server (NTRS)
2004-01-01
Ever wonder whether a still shot from a home video could serve as a "picture perfect" photograph worthy of being framed and proudly displayed on the mantle? Wonder no more. A critical imaging code used to enhance video footage taken from spaceborne imaging instruments is now available within a portable photography tool capable of producing an optimized, high-resolution image from multiple video frames.
Research on compression performance of ultrahigh-definition videos
NASA Astrophysics Data System (ADS)
Li, Xiangqun; He, Xiaohai; Qing, Linbo; Tao, Qingchuan; Wu, Di
2017-11-01
With the popularization of high-definition (HD) images and videos (1920×1080 pixels and above), there are even 4K (3840×2160) television signals and 8 K (8192×4320) ultrahigh-definition videos. The demand for HD images and videos is increasing continuously, along with the increasing data volume. The storage and transmission cannot be properly solved only by virtue of the expansion capacity of hard disks and the update and improvement of transmission devices. Based on the full use of the coding standard high-efficiency video coding (HEVC), super-resolution reconstruction technology, and the correlation between the intra- and the interprediction, we first put forward a "division-compensation"-based strategy to further improve the compression performance of a single image and frame I. Then, by making use of the above thought and HEVC encoder and decoder, a video compression coding frame is designed. HEVC is used inside the frame. Last, with the super-resolution reconstruction technology, the reconstructed video quality is further improved. The experiment shows that by the proposed compression method for a single image (frame I) and video sequence here, the performance is superior to that of HEVC in a low bit rate environment.
Spatiotemporal Pixelization to Increase the Recognition Score of Characters for Retinal Prostheses
Kim, Hyun Seok; Park, Kwang Suk
2017-01-01
Most of the retinal prostheses use a head-fixed camera and a video processing unit. Some studies proposed various image processing methods to improve visual perception for patients. However, previous studies only focused on using spatial information. The present study proposes a spatiotemporal pixelization method mimicking fixational eye movements to generate stimulation images for artificial retina arrays by combining spatial and temporal information. Input images were sampled with a resolution that was four times higher than the number of pixel arrays. We subsampled this image and generated four different phosphene images. We then evaluated the recognition scores of characters by sequentially presenting phosphene images with varying pixel array sizes (6 × 6, 8 × 8 and 10 × 10) and stimulus frame rates (10 Hz, 15 Hz, 20 Hz, 30 Hz, and 60 Hz). The proposed method showed the highest recognition score at a stimulus frame rate of approximately 20 Hz. The method also significantly improved the recognition score for complex characters. This method provides a new way to increase practical resolution over restricted spatial resolution by merging the higher resolution image into high-frame time slots. PMID:29073735
Barnacle Bill in Super Resolution from Insurance Panorama
NASA Technical Reports Server (NTRS)
1998-01-01
Barnacle Bill is a small rock immediately west-northwest of the Mars Pathfinder lander and was the first rock visited by the Sojourner Rover's alpha proton X-ray spectrometer (APXS) instrument. This image shows super resolution techniques applied to the first APXS target rock, which was never imaged with the rover's forward cameras. Super resolution was applied to help to address questions about the texture of this rock and what it might tell us about its mode of origin.
This view of Barnacle Bill was produced by combining the 'Insurance Pan' frames taken while the IMP camera was still in its stowed position on sol2. The composite color frames that make up this anaglyph were produced for both the right and left eye of the IMP. The right eye composite consists of 5 frames, taken with different color filters, the left eye consists of only 1 frame. The resultant image from each eye was enlarged by 500% and then co-added using Adobe Photoshop to produce, in effect, a super-resolution panchromatic frame that is sharper than an individual frame would be. These panchromatic frames were then colorized with the red, green, and blue filtered images from the same sequence. The color balance was adjusted to approximate the true color of Mars.The anaglyph view was produced by combining the left with the right eye color composite frames by assigning the left eye composite view to the red color plane and the right eye composite view to the green and blue color planes (cyan), to produce a stereo anaglyph mosaic. This mosaic can be viewed in 3-D on your computer monitor or in color print form by wearing red-blue 3-D glasses.Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. Barnacle Bill is a small rock immediately west-northwest of the Mars Pathfinder lander and was the first rock visited by the Sojourner Rover's alpha proton X-ray spectrometer (APXS) instrument.Jupiter Data Analysis Program: Analysis of Voyager wideband plasma wave observations
NASA Technical Reports Server (NTRS)
Kurth, W. S.
1983-01-01
Voyager plasma wave wideband frames from the Jovian encounters are analyzed. The 511 frames which were analyzed were chosen on the basis of low-rate spectrum analyzer data from the plasma wave receiver. These frames were obtained in regions and during times of various types of plasma or radio wave activity as determined by the low-rate, low-resolution data and were processed in order to provide high resolution measurements of the plasma wave spectrum for use in the study of a number of outstanding problems. Chorus emissions at Jupiter were analyzed. The detailed temporal and spectral form of the very complex chorus emissions near L = 8 on the Voyager 1 inbound passage was compared to both terrestrial chorus emissions as well as to the theory which was developed to explain the terrestrial waves.
Experimental comparison of high-density scintillators for EMCCD-based gamma ray imaging
NASA Astrophysics Data System (ADS)
Heemskerk, Jan W. T.; Kreuger, Rob; Goorden, Marlies C.; Korevaar, Marc A. N.; Salvador, Samuel; Seeley, Zachary M.; Cherepy, Nerine J.; van der Kolk, Erik; Payne, Stephen A.; Dorenbos, Pieter; Beekman, Freek J.
2012-07-01
Detection of x-rays and gamma rays with high spatial resolution can be achieved with scintillators that are optically coupled to electron-multiplying charge-coupled devices (EMCCDs). These can be operated at typical frame rates of 50 Hz with low noise. In such a set-up, scintillation light within each frame is integrated after which the frame is analyzed for the presence of scintillation events. This method allows for the use of scintillator materials with relatively long decay times of a few milliseconds, not previously considered for use in photon-counting gamma cameras, opening up an unexplored range of dense scintillators. In this paper, we test CdWO4 and transparent polycrystalline ceramics of Lu2O3:Eu and (Gd,Lu)2O3:Eu as alternatives to currently used CsI:Tl in order to improve the performance of EMCCD-based gamma cameras. The tested scintillators were selected for their significantly larger cross-sections at 140 keV (99mTc) compared to CsI:Tl combined with moderate to good light yield. A performance comparison based on gamma camera spatial and energy resolution was done with all tested scintillators having equal (66%) interaction probability at 140 keV. CdWO4, Lu2O3:Eu and (Gd,Lu)2O3:Eu all result in a significantly improved spatial resolution over CsI:Tl, albeit at the cost of reduced energy resolution. Lu2O3:Eu transparent ceramic gives the best spatial resolution: 65 µm full-width-at-half-maximum (FWHM) compared to 147 µm FWHM for CsI:Tl. In conclusion, these ‘slow’ dense scintillators open up new possibilities for improving the spatial resolution of EMCCD-based scintillation cameras.
Application of high-speed photography to chip refining
NASA Astrophysics Data System (ADS)
Stationwala, Mustafa I.; Miller, Charles E.; Atack, Douglas; Karnis, A.
1991-04-01
Several high speed photographic methods have been employed to elucidate the mechanistic aspects of producing mechanical pulp in a disc refiner. Material flow patterns of pulp in a refmer were previously recorded by means of a HYCAM camera and continuous lighting system which provided cine pictures at up to 10,000 pps. In the present work an IMACON camera was used to obtain several series of high resolution, high speed photographs, each photograph containing an eight-frame sequence obtained at a framing rate of 100,000 pps. These high-resolution photographs made it possible to identify the nature of the fibrous material trapped on the bars of the stationary disc. Tangential movement of fibre floes, during the passage of bars on the rotating disc over bars on the stationary disc, was also observed on the stator bars. In addition, using a cinestroboscopic technique a large number of high resolution pictures were taken at three different positions of the rotating disc relative to the stationary disc. These pictures were computer analyzed, statistically, to determine the fractional coverage of the bars of the stationary disc with pulp. Information obtained from these studies provides new insights into the mechanism of the refining process.
Full-Frame Reference for Test Photo of Moon
NASA Technical Reports Server (NTRS)
2005-01-01
This pair of views shows how little of the full image frame was taken up by the Moon in test images taken Sept. 8, 2005, by the High Resolution Imaging Science Experiment (HiRISE) camera on NASA's Mars Reconnaissance Orbiter. The Mars-bound camera imaged Earth's Moon from a distance of about 10 million kilometers (6 million miles) away -- 26 times the distance between Earth and the Moon -- as part of an activity to test and calibrate the camera. The images are very significant because they show that the Mars Reconnaissance Orbiter spacecraft and this camera can properly operate together to collect very high-resolution images of Mars. The target must move through the camera's telescope view in just the right direction and speed to acquire a proper image. The day's test images also demonstrate that the focus mechanism works properly with the telescope to produce sharp images. Out of the 20,000-pixel-by-6,000-pixel full frame, the Moon's diameter is about 340 pixels, if the full Moon could be seen. The illuminated crescent is about 60 pixels wide, and the resolution is about 10 kilometers (6 miles) per pixel. At Mars, the entire image region will be filled with high-resolution information. The Mars Reconnaissance Orbiter, launched on Aug. 12, 2005, is on course to reach Mars on March 10, 2006. After gradually adjusting the shape of its orbit for half a year, it will begin its primary science phase in November 2006. From the mission's planned science orbit about 300 kilometers (186 miles) above the surface of Mars, the high resolution camera will be able to discern features as small as one meter or yard across. The Mars Reconnaissance Orbiter mission is managed by NASA's Jet Propulsion Laboratory, a division of the California Institute of Technology, Pasadena, for the NASA Science Mission Directorate. Lockheed Martin Space Systems, Denver, prime contractor for the project, built the spacecraft. Ball Aerospace & Technologies Corp., Boulder, Colo., built the High Resolution Imaging Science Experiment instrument for the University of Arizona, Tucson, to provide to the mission. The HiRISE Operations Center at the University of Arizona processes images from the camera.A high resolution cavity BPM for the CLIC Test Facility
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chritin, N.; Schmickler, H.; Soby, L.
2010-08-01
In frame of the development of a high resolution BPM system for the CLIC Main Linac we present the design of a cavity BPM prototype. It consists of a waveguide loaded dipole mode resonator and a monopole mode reference cavity, both operating at 15 GHz, to be compatible with the bunch frequencies at the CLIC Test Facility. Requirements, design concept, numerical analysis, and practical considerations are discussed.
High-Speed Videography Overview
NASA Astrophysics Data System (ADS)
Miller, C. E.
1989-02-01
The field of high-speed videography (HSV) has continued to mature in recent years, due to the introduction of a mixture of new technology and extensions of existing technology. Recent low frame-rate innovations have the potential to dramatically expand the areas of information gathering and motion analysis at all frame-rates. Progress at the 0 - rate is bringing the battle of film versus video to the field of still photography. The pressure to push intermediate frame rates higher continues, although the maximum achievable frame rate has remained stable for several years. Higher maximum recording rates appear technologically practical, but economic factors impose severe limitations to development. The application of diverse photographic techniques to video-based systems is under-exploited. The basics of HSV apply to other fields, such as machine vision and robotics. Present motion analysis systems continue to function mainly as an instant replay replacement for high-speed movie film cameras. The interrelationship among lighting, shuttering and spatial resolution is examined.
Super Resolution Image of Yogi
NASA Technical Reports Server (NTRS)
1997-01-01
Yogi is a meter-size rock about 5 meters northwest of the Mars Pathfinder lander and was the second rock visited by the Sojourner Rover's alpha proton X-ray spectrometer (APXS) instrument. This mosaic shows super resolution techniques applied to the second APXS target rock, which was poorly illuminated in the rover's forward camera view taken before the instrument was deployed. Super resolution was applied to help to address questions about the texture of this rock and what it might tell us about its mode of origin.
This mosaic of Yogi was produced by combining four 'Super Pan' frames taken with the IMP camera. This composite color mosaic consists of 7 frames from the right eye, taken with different color filters that were enlarged by 500% and then co-added using Adobe Photoshop to produce, in effect, a super-resolution panchromatic frame that is sharper than an individual frame would be. This panchromatic frame was then colorized with the red, green, and blue filtered images from the same sequence. The color balance was adjusted to approximate the true color of Mars. Shadows were processed separately from the rest of the rock and combined with the rest of the scene to bring out details in the shadow of Yogi that would be too dark to view at the same time as the sunlit surfaces.Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is a division of the California Institute of Technology (Caltech).Advances in indirect detector systems for ultra high-speed hard X-ray imaging with synchrotron light
NASA Astrophysics Data System (ADS)
Olbinado, M. P.; Grenzer, J.; Pradel, P.; De Resseguier, T.; Vagovic, P.; Zdora, M.-C.; Guzenko, V. A.; David, C.; Rack, A.
2018-04-01
We report on indirect X-ray detector systems for various full-field, ultra high-speed X-ray imaging methodologies, such as X-ray phase-contrast radiography, diffraction topography, grating interferometry and speckle-based imaging performed at the hard X-ray imaging beamline ID19 of the European Synchrotron—ESRF. Our work highlights the versatility of indirect X-ray detectors to multiple goals such as single synchrotron pulse isolation, multiple-frame recording up to millions frames per second, high efficiency, and high spatial resolution. Besides the technical advancements, potential applications are briefly introduced and discussed.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Duchaineau, M.; Wolinsky, M.; Sigeti, D.E.
Terrain visualization is a difficult problem for applications requiring accurate images of large datasets at high frame rates, such as flight simulation and ground-based aircraft testing using synthetic sensor stimulation. On current graphics hardware, the problem is to maintain dynamic, view-dependent triangle meshes and texture maps that produce good images at the required frame rate. We present an algorithm for constructing triangle meshes that optimizes flexible view-dependent error metrics, produces guaranteed error bounds, achieves specified triangle counts directly, and uses frame-to-frame coherence to operate at high frame rates for thousands of triangles per frame. Our method, dubbed Real-time Optimally Adaptingmore » Meshes (ROAM), uses two priority queues to drive split and merge operations that maintain continuous triangulations built from pre-processed bintree triangles. We introduce two additional performance optimizations: incremental triangle stripping and priority-computation deferral lists. ROAM execution time is proportionate to the number of triangle changes per frame, which is typically a few percent of the output mesh size, hence ROAM performance is insensitive to the resolution and extent of the input terrain. Dynamic terrain and simple vertex morphing are supported.« less
SuperSegger: robust image segmentation, analysis and lineage tracking of bacterial cells.
Stylianidou, Stella; Brennan, Connor; Nissen, Silas B; Kuwada, Nathan J; Wiggins, Paul A
2016-11-01
Many quantitative cell biology questions require fast yet reliable automated image segmentation to identify and link cells from frame-to-frame, and characterize the cell morphology and fluorescence. We present SuperSegger, an automated MATLAB-based image processing package well-suited to quantitative analysis of high-throughput live-cell fluorescence microscopy of bacterial cells. SuperSegger incorporates machine-learning algorithms to optimize cellular boundaries and automated error resolution to reliably link cells from frame-to-frame. Unlike existing packages, it can reliably segment microcolonies with many cells, facilitating the analysis of cell-cycle dynamics in bacteria as well as cell-contact mediated phenomena. This package has a range of built-in capabilities for characterizing bacterial cells, including the identification of cell division events, mother, daughter and neighbouring cells, and computing statistics on cellular fluorescence, the location and intensity of fluorescent foci. SuperSegger provides a variety of postprocessing data visualization tools for single cell and population level analysis, such as histograms, kymographs, frame mosaics, movies and consensus images. Finally, we demonstrate the power of the package by analyzing lag phase growth with single cell resolution. © 2016 John Wiley & Sons Ltd.
NASA Technical Reports Server (NTRS)
1982-01-01
The 241 mm photographic product produced by the Goddard Space Flight Center Data Management System for LANDSAT-D is described. Film type and format, image dimensions, frame ID, gray scale, resolution patterns, registration marks, etc. are addressed.
High frame-rate resolution of cell division during Candida albicans filamentation
Thomson, Darren D.; Berman, Judith; Brand, Alexandra C.
2016-01-01
The commensal yeast, Candida albicans, is an opportunistic pathogen in humans and forms filaments called hyphae and pseudohyphae, in which cell division requires precise temporal and spatial control to produce mononuclear cell compartments. High-frame-rate live-cell imaging (1 frame/min) revealed that nuclear division did not occur across the septal plane. We detected the presence of nucleolar fragments that may be extrachromosomal molecules carrying the ribosomal RNA genes. Cells occasionally maintained multiple nucleoli, suggesting either polyploidy, multiple nuclei and/or aneuploidy of ChrR., while the migration pattern of sister nuclei differed between unbranched and branched hyphae. The presented movie challenges and extends previous concepts of C. albicans cell division. PMID:26854071
Investigating plasma viscosity with fast framing photography in the ZaP-HD Flow Z-Pinch experiment
NASA Astrophysics Data System (ADS)
Weed, Jonathan Robert
The ZaP-HD Flow Z-Pinch experiment investigates the stabilizing effect of sheared axial flows while scaling toward a high-energy-density laboratory plasma (HEDLP > 100 GPa). Stabilizing flows may persist until viscous forces dissipate a sheared flow profile. Plasma viscosity is investigated by measuring scale lengths in turbulence intentionally introduced in the plasma flow. A boron nitride turbulence-tripping probe excites small scale length turbulence in the plasma, and fast framing optical cameras are used to study time-evolved turbulent structures and viscous dissipation. A Hadland Imacon 790 fast framing camera is modified for digital image capture, but features insufficient resolution to study turbulent structures. A Shimadzu HPV-X camera captures the evolution of turbulent structures with great spatial and temporal resolution, but is unable to resolve the anticipated Kolmogorov scale in ZaP-HD as predicted by a simplified pinch model.
Qu, Bin; Huang, Ying; Wang, Weiyuan; Sharma, Prateek; Kuhls-Gilcrist, Andrew T.; Cartwright, Alexander N.; Titus, Albert H.; Bednarek, Daniel R.; Rudin, Stephen
2011-01-01
Use of an extensible array of Electron Multiplying CCDs (EMCCDs) in medical x-ray imager applications was demonstrated for the first time. The large variable electronic-gain (up to 2000) and small pixel size of EMCCDs provide effective suppression of readout noise compared to signal, as well as high resolution, enabling the development of an x-ray detector with far superior performance compared to conventional x-ray image intensifiers and flat panel detectors. We are developing arrays of EMCCDs to overcome their limited field of view (FOV). In this work we report on an array of two EMCCD sensors running simultaneously at a high frame rate and optically focused on a mammogram film showing calcified ducts. The work was conducted on an optical table with a pulsed LED bar used to provide a uniform diffuse light onto the film to simulate x-ray projection images. The system can be selected to run at up to 17.5 frames per second or even higher frame rate with binning. Integration time for the sensors can be adjusted from 1 ms to 1000 ms. Twelve-bit correlated double sampling AD converters were used to digitize the images, which were acquired by a National Instruments dual-channel Camera Link PC board in real time. A user-friendly interface was programmed using LabVIEW to save and display 2K × 1K pixel matrix digital images. The demonstration tiles a 2 × 1 array to acquire increased-FOV stationary images taken at different gains and fluoroscopic-like videos recorded by scanning the mammogram simultaneously with both sensors. The results show high resolution and high dynamic range images stitched together with minimal adjustments needed. The EMCCD array design allows for expansion to an M×N array for arbitrarily larger FOV, yet with high resolution and large dynamic range maintained. PMID:23505330
The application of high-speed TV-holography to time-resolved vibration measurements
NASA Astrophysics Data System (ADS)
Buckberry, C.; Reeves, M.; Moore, A. J.; Hand, D. P.; Barton, J. S.; Jones, J. D. C.
1999-10-01
We describe an electronic speckle pattern interferometer (ESPI) system that has enabled non-harmonic vibrations to be measured with μs temporal resolution. The short exposure period and high framing rate of a high-speed camera at up to 40,500 frames per second allow low-power CW laser illumination and fibre-optic beam delivery to be used, rather than the high peak power pulsed lasers normally used in ESPI for transient measurement. The technique has been demonstrated in the laboratory and tested in preliminary industrial trials. The ability to measure vibration with high spatial and temporal resolution, which is not provided by techniques such as scanning laser vibrometry, has many applications in manufacturing design, and in an illustrative application described here revealed previously unmeasured “rocking” vibrations of a car door. It has been possible to make the measurement on the door as part of a complete vehicle standing on its own tyres, wheels and suspension, and where the excitation was generated by the running of the vehicle's own engine.
Prabhu, David; Mehanna, Emile; Gargesha, Madhusudhana; Brandt, Eric; Wen, Di; van Ditzhuijzen, Nienke S; Chamie, Daniel; Yamamoto, Hirosada; Fujino, Yusuke; Alian, Ali; Patel, Jaymin; Costa, Marco; Bezerra, Hiram G; Wilson, David L
2016-04-01
Evidence suggests high-resolution, high-contrast, [Formula: see text] intravascular optical coherence tomography (IVOCT) can distinguish plaque types, but further validation is needed, especially for automated plaque characterization. We developed experimental and three-dimensional (3-D) registration methods to provide validation of IVOCT pullback volumes using microscopic, color, and fluorescent cryo-image volumes with optional registered cryo-histology. A specialized registration method matched IVOCT pullback images acquired in the catheter reference frame to a true 3-D cryo-image volume. Briefly, an 11-parameter registration model including a polynomial virtual catheter was initialized within the cryo-image volume, and perpendicular images were extracted, mimicking IVOCT image acquisition. Virtual catheter parameters were optimized to maximize cryo and IVOCT lumen overlap. Multiple assessments suggested that the registration error was better than the [Formula: see text] spacing between IVOCT image frames. Tests on a digital synthetic phantom gave a registration error of only [Formula: see text] (signed distance). Visual assessment of randomly presented nearby frames suggested registration accuracy within 1 IVOCT frame interval ([Formula: see text]). This would eliminate potential misinterpretations confronted by the typical histological approaches to validation, with estimated 1-mm errors. The method can be used to create annotated datasets and automated plaque classification methods and can be extended to other intravascular imaging modalities.
Negoita, Madalina; Zolgharni, Massoud; Dadkho, Elham; Pernigo, Matteo; Mielewczik, Michael; Cole, Graham D; Dhutia, Niti M; Francis, Darrel P
2016-09-01
To determine the optimal frame rate at which reliable heart walls velocities can be assessed by speckle tracking. Assessing left ventricular function with speckle tracking is useful in patient diagnosis but requires a temporal resolution that can follow myocardial motion. In this study we investigated the effect of different frame rates on the accuracy of speckle tracking results, highlighting the temporal resolution where reliable results can be obtained. 27 patients were scanned at two different frame rates at their resting heart rate. From all acquired loops, lower temporal resolution image sequences were generated by dropping frames, decreasing the frame rate by up to 10-fold. Tissue velocities were estimated by automated speckle tracking. Above 40 frames/s the peak velocity was reliably measured. When frame rate was lower, the inter-frame interval containing the instant of highest velocity also contained lower velocities, and therefore the average velocity in that interval was an underestimate of the clinically desired instantaneous maximum velocity. The higher the frame rate, the more accurately maximum velocities are identified by speckle tracking, until the frame rate drops below 40 frames/s, beyond which there is little increase in peak velocity. We provide in an online supplement the vendor-independent software we used for automatic speckle-tracked velocity assessment to help others working in this field. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
High-speed Particle Image Velocimetry Near Surfaces
Lu, Louise; Sick, Volker
2013-01-01
Multi-dimensional and transient flows play a key role in many areas of science, engineering, and health sciences but are often not well understood. The complex nature of these flows may be studied using particle image velocimetry (PIV), a laser-based imaging technique for optically accessible flows. Though many forms of PIV exist that extend the technique beyond the original planar two-component velocity measurement capabilities, the basic PIV system consists of a light source (laser), a camera, tracer particles, and analysis algorithms. The imaging and recording parameters, the light source, and the algorithms are adjusted to optimize the recording for the flow of interest and obtain valid velocity data. Common PIV investigations measure two-component velocities in a plane at a few frames per second. However, recent developments in instrumentation have facilitated high-frame rate (> 1 kHz) measurements capable of resolving transient flows with high temporal resolution. Therefore, high-frame rate measurements have enabled investigations on the evolution of the structure and dynamics of highly transient flows. These investigations play a critical role in understanding the fundamental physics of complex flows. A detailed description for performing high-resolution, high-speed planar PIV to study a transient flow near the surface of a flat plate is presented here. Details for adjusting the parameter constraints such as image and recording properties, the laser sheet properties, and processing algorithms to adapt PIV for any flow of interest are included. PMID:23851899
Heterogeneous CPU-GPU moving targets detection for UAV video
NASA Astrophysics Data System (ADS)
Li, Maowen; Tang, Linbo; Han, Yuqi; Yu, Chunlei; Zhang, Chao; Fu, Huiquan
2017-07-01
Moving targets detection is gaining popularity in civilian and military applications. On some monitoring platform of motion detection, some low-resolution stationary cameras are replaced by moving HD camera based on UAVs. The pixels of moving targets in the HD Video taken by UAV are always in a minority, and the background of the frame is usually moving because of the motion of UAVs. The high computational cost of the algorithm prevents running it at higher resolutions the pixels of frame. Hence, to solve the problem of moving targets detection based UAVs video, we propose a heterogeneous CPU-GPU moving target detection algorithm for UAV video. More specifically, we use background registration to eliminate the impact of the moving background and frame difference to detect small moving targets. In order to achieve the effect of real-time processing, we design the solution of heterogeneous CPU-GPU framework for our method. The experimental results show that our method can detect the main moving targets from the HD video taken by UAV, and the average process time is 52.16ms per frame which is fast enough to solve the problem.
A two-step A/D conversion and column self-calibration technique for low noise CMOS image sensors.
Bae, Jaeyoung; Kim, Daeyun; Ham, Seokheon; Chae, Youngcheol; Song, Minkyu
2014-07-04
In this paper, a 120 frames per second (fps) low noise CMOS Image Sensor (CIS) based on a Two-Step Single Slope ADC (TS SS ADC) and column self-calibration technique is proposed. The TS SS ADC is suitable for high speed video systems because its conversion speed is much faster (by more than 10 times) than that of the Single Slope ADC (SS ADC). However, there exist some mismatching errors between the coarse block and the fine block due to the 2-step operation of the TS SS ADC. In general, this makes it difficult to implement the TS SS ADC beyond a 10-bit resolution. In order to improve such errors, a new 4-input comparator is discussed and a high resolution TS SS ADC is proposed. Further, a feedback circuit that enables column self-calibration to reduce the Fixed Pattern Noise (FPN) is also described. The proposed chip has been fabricated with 0.13 μm Samsung CIS technology and the chip satisfies the VGA resolution. The pixel is based on the 4-TR Active Pixel Sensor (APS). The high frame rate of 120 fps is achieved at the VGA resolution. The measured FPN is 0.38 LSB, and measured dynamic range is about 64.6 dB.
Resolution enhancement of tri-stereo remote sensing images by super resolution methods
NASA Astrophysics Data System (ADS)
Tuna, Caglayan; Akoguz, Alper; Unal, Gozde; Sertel, Elif
2016-10-01
Super resolution (SR) refers to generation of a High Resolution (HR) image from a decimated, blurred, low-resolution (LR) image set, which can be either a single frame or multi-frame that contains a collection of several images acquired from slightly different views of the same observation area. In this study, we propose a novel application of tri-stereo Remote Sensing (RS) satellite images to the super resolution problem. Since the tri-stereo RS images of the same observation area are acquired from three different viewing angles along the flight path of the satellite, these RS images are properly suited to a SR application. We first estimate registration between the chosen reference LR image and other LR images to calculate the sub pixel shifts among the LR images. Then, the warping, blurring and down sampling matrix operators are created as sparse matrices to avoid high memory and computational requirements, which would otherwise make the RS-SR solution impractical. Finally, the overall system matrix, which is constructed based on the obtained operator matrices is used to obtain the estimate HR image in one step in each iteration of the SR algorithm. Both the Laplacian and total variation regularizers are incorporated separately into our algorithm and the results are presented to demonstrate an improved quantitative performance against the standard interpolation method as well as improved qualitative results due expert evaluations.
Characterization of a 512x512-pixel 8-output full-frame CCD for high-speed imaging
NASA Astrophysics Data System (ADS)
Graeve, Thorsten; Dereniak, Eustace L.
1993-01-01
The characterization of a 512 by 512 pixel, eight-output full frame CCD manufactured by English Electric Valve under part number CCD13 is discussed. This device is a high- resolution Silicon-based array designed for visible imaging applications at readout periods as low as two milliseconds. The characterization of the device includes mean-variance analysis to determine read noise and dynamic range, as well as charge transfer efficiency, MTF, and quantum efficiency measurements. Dark current and non-uniformity issues on a pixel-to-pixel basis and between individual outputs are also examined. The characterization of the device is restricted by hardware limitations to a one MHz pixel rate, corresponding to a 40 ms readout time. However, subsections of the device have been operated at up to an equivalent 100 frames per second. To maximize the frame rate, the CCD is illuminated by a synchronized strobe flash in between frame readouts. The effects of the strobe illumination on the imagery obtained from the device is discussed.
High-Resolution Global Geologic Map of Ceres from NASA Dawn Mission
NASA Astrophysics Data System (ADS)
Williams, D. A.; Buczkowski, D. L.; Crown, D. A.; Frigeri, A.; Hughson, K.; Kneissl, T.; Krohn, K.; Mest, S. C.; Pasckert, J. H.; Platz, T.; Ruesch, O.; Schulzeck, F.; Scully, J. E. C.; Sizemore, H. G.; Nass, A.; Jaumann, R.; Raymond, C. A.; Russell, C. T.
2018-06-01
This presentation will discuss the completed 1:4,000,000 global geologic map of dwarf planet Ceres derived from Dawn Framing Camera Low Altitude Mapping Orbit (LAMo) images, combining 15 quadrangle maps.
NASA Astrophysics Data System (ADS)
Cabanski, Wolfgang A.; Breiter, Rainer; Koch, R.; Mauk, Karl-Heinz; Rode, Werner; Ziegler, Johann; Eberhardt, Kurt; Oelmaier, Reinhard; Schneider, Harald; Walther, Martin
2000-07-01
Full video format focal plane array (FPA) modules with up to 640 X 512 pixels have been developed for high resolution imaging applications in either mercury cadmium telluride (MCT) mid wave (MWIR) infrared (IR) or platinum silicide (PtSi) and quantum well infrared photodetector (QWIP) technology as low cost alternatives to MCT for high performance IR imaging in the MWIR or long wave spectral band (LWIR). For the QWIP's, a new photovoltaic technology was introduced for improved NETD performance and higher dynamic range. MCT units provide fast frame rates > 100 Hz together with state of the art thermal resolution NETD < 20 mK for short snapshot integration times of typically 2 ms. PtSi and QWIP modules are usually operated in a rolling frame integration mode with frame rates of 30 - 60 Hz and provide thermal resolutions of NETD < 80 mK for PtSi and NETD < 20 mK for QWIP, respectively. Due to the lower quantum efficiency compared to MCT, however, the integration time is typically chosen to be as long 10 - 20 ms. The heat load of the integrated detector cooler assemblies (IDCAs) could be reduced to an amount as low, that a 1 W split liner cooler provides sufficient cooling power to operate the modules -- including the QWIP with 60 K operation temperature -- at ambient temperatures up to 65 degrees Celsius. Miniaturized command/control electronics (CCE) available for all modules provide a standardized digital interface, with 14 bit analogue to digital conversion for state to the art correctability, access to highly dynamic scenes without any loss of information and simplified exchangeability of the units. New modular image processing hardware platforms and software for image visualization and nonuniformity correction including scene based self learning algorithms had to be developed to accomplish for the high data rates of up to 18 M pixels/s with 14-bit deep data, allowing to take into account nonlinear effects to access the full NETD by accurate reduction of residual fixed pattern noise. The main features of these modules are summarized together with measured performance data for long range detection systems with moderately fast to slow F-numbers like F/2.0 - F/3.5. An outlook shows most recent activities at AIM, heading for multicolor and faster frame rate detector modules based on MCT devices.
Video-rate or high-precision: a flexible range imaging camera
NASA Astrophysics Data System (ADS)
Dorrington, Adrian A.; Cree, Michael J.; Carnegie, Dale A.; Payne, Andrew D.; Conroy, Richard M.; Godbaz, John P.; Jongenelen, Adrian P. P.
2008-02-01
A range imaging camera produces an output similar to a digital photograph, but every pixel in the image contains distance information as well as intensity. This is useful for measuring the shape, size and location of objects in a scene, hence is well suited to certain machine vision applications. Previously we demonstrated a heterodyne range imaging system operating in a relatively high resolution (512-by-512) pixels and high precision (0.4 mm best case) configuration, but with a slow measurement rate (one every 10 s). Although this high precision range imaging is useful for some applications, the low acquisition speed is limiting in many situations. The system's frame rate and length of acquisition is fully configurable in software, which means the measurement rate can be increased by compromising precision and image resolution. In this paper we demonstrate the flexibility of our range imaging system by showing examples of high precision ranging at slow acquisition speeds and video-rate ranging with reduced ranging precision and image resolution. We also show that the heterodyne approach and the use of more than four samples per beat cycle provides better linearity than the traditional homodyne quadrature detection approach. Finally, we comment on practical issues of frame rate and beat signal frequency selection.
Machine Learning Based Single-Frame Super-Resolution Processing for Lensless Blood Cell Counting
Huang, Xiwei; Jiang, Yu; Liu, Xu; Xu, Hang; Han, Zhi; Rong, Hailong; Yang, Haiping; Yan, Mei; Yu, Hao
2016-01-01
A lensless blood cell counting system integrating microfluidic channel and a complementary metal oxide semiconductor (CMOS) image sensor is a promising technique to miniaturize the conventional optical lens based imaging system for point-of-care testing (POCT). However, such a system has limited resolution, making it imperative to improve resolution from the system-level using super-resolution (SR) processing. Yet, how to improve resolution towards better cell detection and recognition with low cost of processing resources and without degrading system throughput is still a challenge. In this article, two machine learning based single-frame SR processing types are proposed and compared for lensless blood cell counting, namely the Extreme Learning Machine based SR (ELMSR) and Convolutional Neural Network based SR (CNNSR). Moreover, lensless blood cell counting prototypes using commercial CMOS image sensors and custom designed backside-illuminated CMOS image sensors are demonstrated with ELMSR and CNNSR. When one captured low-resolution lensless cell image is input, an improved high-resolution cell image will be output. The experimental results show that the cell resolution is improved by 4×, and CNNSR has 9.5% improvement over the ELMSR on resolution enhancing performance. The cell counting results also match well with a commercial flow cytometer. Such ELMSR and CNNSR therefore have the potential for efficient resolution improvement in lensless blood cell counting systems towards POCT applications. PMID:27827837
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vijayan, S; Rana, V; Nagesh, S Setlur
Purpose: To determine the reduction of integral dose to the patient when using the micro-angiographic fluoroscope (MAF) compared to when using the standard flat-panel detector (FPD) for the techniques used during neurointerventional procedures. Methods: The MAF is a small field-of-view, high resolution x-ray detector which captures 1024 x 1024 pixels with an effective pixel size of 35μm and is capable of real-time imaging up to 30 frames per second. The MAF was used in neuro-interventions during those parts of the procedure when high resolution was needed and the FPD was used otherwise. The technique parameters were recorded when each detectormore » was used and the kerma-area-product (KAP) per image frame was determined. KAP values were calculated for seven neuro interventions using premeasured calibration files of output as a function of kVp and beam filtration and included the attenuation of the patient table for the frontal projections to be more representative of integral patient dose. The air kerma at the patient entrance was multiplied by the beam area at that point to obtain the KAP values. The ranges of KAP values per frame were determined for the range of technique parameters used during the clinical procedures. To appreciate the benefit of the higher MAF resolution in the region of interventional activity, DA technique parameters were generally used with the MAF. Results: The lowest and highest values of KAP per frame for the MAF in DA mode were 4 and 50 times lower, respectively, compared to those of the FPD in pulsed fluoroscopy mode. Conclusion: The MAF was used in those parts of the clinical procedures when high resolution and image quality was essential. The integral patient dose as represented by the KAP value was substantially lower when using the MAF than when using the FPD due to the much smaller volume of tissue irradiated. This research was supported in part by Toshiba Medical Systems Corporation and NIH Grant R01EB002873.« less
Okuda, Kyohei; Sakimoto, Shota; Fujii, Susumu; Ida, Tomonobu; Moriyama, Shigeru
The frame-of-reference using computed-tomography (CT) coordinate system on single-photon emission computed tomography (SPECT) reconstruction is one of the advanced characteristics of the xSPECT reconstruction system. The aim of this study was to reveal the influence of the high-resolution frame-of-reference on the xSPECT reconstruction. 99m Tc line-source phantom and National Electrical Manufacturers Association (NEMA) image quality phantom were scanned using the SPECT/CT system. xSPECT reconstructions were performed with the reference CT images in different sizes of the display field-of-view (DFOV) and pixel. The pixel sizes of the reconstructed xSPECT images were close to 2.4 mm, which is acquired as originally projection data, even if the reference CT resolution was varied. The full width at half maximum (FWHM) of the line-source, absolute recovery coefficient, and background variability of image quality phantom were independent on the sizes of DFOV in the reference CT images. The results of this study revealed that the image quality of the reconstructed xSPECT images is not influenced by the resolution of frame-of-reference on SPECT reconstruction.
EIT image reconstruction with four dimensional regularization.
Dai, Tao; Soleimani, Manuchehr; Adler, Andy
2008-09-01
Electrical impedance tomography (EIT) reconstructs internal impedance images of the body from electrical measurements on body surface. The temporal resolution of EIT data can be very high, although the spatial resolution of the images is relatively low. Most EIT reconstruction algorithms calculate images from data frames independently, although data are actually highly correlated especially in high speed EIT systems. This paper proposes a 4-D EIT image reconstruction for functional EIT. The new approach is developed to directly use prior models of the temporal correlations among images and 3-D spatial correlations among image elements. A fast algorithm is also developed to reconstruct the regularized images. Image reconstruction is posed in terms of an augmented image and measurement vector which are concatenated from a specific number of previous and future frames. The reconstruction is then based on an augmented regularization matrix which reflects the a priori constraints on temporal and 3-D spatial correlations of image elements. A temporal factor reflecting the relative strength of the image correlation is objectively calculated from measurement data. Results show that image reconstruction models which account for inter-element correlations, in both space and time, show improved resolution and noise performance, in comparison to simpler image models.
Dual-slit confocal light sheet microscopy for in vivo whole-brain imaging of zebrafish
Yang, Zhe; Mei, Li; Xia, Fei; Luo, Qingming; Fu, Ling; Gong, Hui
2015-01-01
In vivo functional imaging at single-neuron resolution is an important approach to visualize biological processes in neuroscience. Light sheet microscopy (LSM) is a cutting edge in vivo imaging technique that provides micron-scale spatial resolution at high frame rate. Due to the scattering and absorption of tissue, however, conventional LSM is inadequate to resolve cells because of the attenuated signal to noise ratio (SNR). Using dual-beam illumination and confocal dual-slit detection, here a dual-slit confocal LSM is demonstrated to obtain the SNR enhanced images with frame rate twice as high as line confocal LSM method. Through theoretical calculations and experiments, the correlation between the slit’s width and SNR was determined to optimize the image quality. In vivo whole brain structural imaging stacks and the functional imaging sequences of single slice were obtained for analysis of calcium activities at single-cell resolution. A two-fold increase in imaging speed of conventional confocal LSM makes it possible to capture the sequence of the neurons’ activities and help reveal the potential functional connections in the whole zebrafish’s brain. PMID:26137381
An interferometer for high-resolution optical surveillance from GEO - internal metrology breadboard
NASA Astrophysics Data System (ADS)
Bonino, L.; Bresciani, F.; Piasini, G.; Pisani, M.; Cabral, A.; Rebordão, J.; Musso, F.
2017-11-01
This paper describes the internal metrology breadboard development activities performed in the frame of the EUCLID CEPA 9 RTP 9.9 "High Resolution Optical Satellite Sensor" project of the WEAO Research Cell by AAS-I and INETI. The Michelson Interferometer Testbed demonstrates the possibility of achieving a cophasing condition between two arms of the optical interferometer starting from a large initial white light Optical Path Difference (OPD) unbalance and of maintaining the fringe pattern stabilized in presence of disturbances.
Inexpensive Neutron Imaging Cameras Using CCDs for Astronomy
NASA Astrophysics Data System (ADS)
Hewat, A. W.
We have developed inexpensive neutron imaging cameras using CCDs originally designed for amateur astronomical observation. The low-light, high resolution requirements of such CCDs are similar to those for neutron imaging, except that noise as well as cost is reduced by using slower read-out electronics. For example, we use the same 2048x2048 pixel ;Kodak; KAI-4022 CCD as used in the high performance PCO-2000 CCD camera, but our electronics requires ∼5 sec for full-frame read-out, ten times slower than the PCO-2000. Since neutron exposures also require several seconds, this is not seen as a serious disadvantage for many applications. If higher frame rates are needed, the CCD unit on our camera can be easily swapped for a faster readout detector with similar chip size and resolution, such as the PCO-2000 or the sCMOS PCO.edge 4.2.
Augmented Reality for Maintenance and Repair (ARMAR)
2007-08-01
800×600 resolution monocular display, whose small size and lack of an opaque “ frame ”, provides the closest experience to an eyeglass form factor, and...Alternatively, fiducials could be mounted on lightweight rigid frames that are attached to predetermined points on the maintained system. Figure...stereo at 800×600 resolution, thirty frames per second, creating a compelling experience of an augmented workspace. Based on our preliminary
Parallelization of a blind deconvolution algorithm
NASA Astrophysics Data System (ADS)
Matson, Charles L.; Borelli, Kathy J.
2006-09-01
Often it is of interest to deblur imagery in order to obtain higher-resolution images. Deblurring requires knowledge of the blurring function - information that is often not available separately from the blurred imagery. Blind deconvolution algorithms overcome this problem by jointly estimating both the high-resolution image and the blurring function from the blurred imagery. Because blind deconvolution algorithms are iterative in nature, they can take minutes to days to deblur an image depending how many frames of data are used for the deblurring and the platforms on which the algorithms are executed. Here we present our progress in parallelizing a blind deconvolution algorithm to increase its execution speed. This progress includes sub-frame parallelization and a code structure that is not specialized to a specific computer hardware architecture.
NASA Technical Reports Server (NTRS)
2000-01-01
Video Pics is a software program that generates high-quality photos from video. The software was developed under an SBIR contract with Marshall Space Flight Center by Redhawk Vision, Inc.--a subsidiary of Irvine Sensors Corporation. Video Pics takes information content from multiple frames of video and enhances the resolution of a selected frame. The resulting image has enhanced sharpness and clarity like that of a 35 mm photo. The images are generated as digital files and are compatible with image editing software.
NASA Astrophysics Data System (ADS)
Takashima, Ichiro; Kajiwara, Riichi; Murano, Kiyo; Iijima, Toshio; Morinaka, Yasuhiro; Komobuchi, Hiroyoshi
2001-04-01
We have designed and built a high-speed CCD imaging system for monitoring neural activity in an exposed animal cortex stained with a voltage-sensitive dye. Two types of custom-made CCD sensors were developed for this system. The type I chip has a resolution of 2664 (H) X 1200 (V) pixels and a wide imaging area of 28.1 X 13.8 mm, while the type II chip has 1776 X 1626 pixels and an active imaging area of 20.4 X 18.7 mm. The CCD arrays were constructed with multiple output amplifiers in order to accelerate the readout rate. The two chips were divided into either 24 (I) or 16 (II) distinct areas that were driven in parallel. The parallel CCD outputs were digitized by 12-bit A/D converters and then stored in the frame memory. The frame memory was constructed with synchronous DRAM modules, which provided a capacity of 128 MB per channel. On-chip and on-memory binning methods were incorporated into the system, e.g., this enabled us to capture 444 X 200 pixel-images for periods of 36 seconds at a rate of 500 frames/second. This system was successfully used to visualize neural activity in the cortices of rats, guinea pigs, and monkeys.
NASA Astrophysics Data System (ADS)
Hong, Guosong; Zou, Yingping; Antaris, Alexander L.; Diao, Shuo; Wu, Di; Cheng, Kai; Zhang, Xiaodong; Chen, Changxin; Liu, Bo; He, Yuehui; Wu, Justin Z.; Yuan, Jun; Zhang, Bo; Tao, Zhimin; Fukunaga, Chihiro; Dai, Hongjie
2014-06-01
In vivo fluorescence imaging in the second near-infrared window (1.0-1.7 μm) can afford deep tissue penetration and high spatial resolution, owing to the reduced scattering of long-wavelength photons. Here we synthesize a series of low-bandgap donor/acceptor copolymers with tunable emission wavelengths of 1,050-1,350 nm in this window. Non-covalent functionalization with phospholipid-polyethylene glycol results in water-soluble and biocompatible polymeric nanoparticles, allowing for live cell molecular imaging at >1,000 nm with polymer fluorophores for the first time. Importantly, the high quantum yield of the polymer allows for in vivo, deep-tissue and ultrafast imaging of mouse arterial blood flow with an unprecedented frame rate of >25 frames per second. The high time-resolution results in spatially and time resolved imaging of the blood flow pattern in cardiogram waveform over a single cardiac cycle (~200 ms) of a mouse, which has not been observed with fluorescence imaging in this window before.
NASA Astrophysics Data System (ADS)
Kuroda, R.; Sugawa, S.
2017-02-01
Ultra-high speed (UHS) CMOS image sensors with on-chop analog memories placed on the periphery of pixel array for the visualization of UHS phenomena are overviewed in this paper. The developed UHS CMOS image sensors consist of 400H×256V pixels and 128 memories/pixel, and the readout speed of 1Tpixel/sec is obtained, leading to 10 Mfps full resolution video capturing with consecutive 128 frames, and 20 Mfps half resolution video capturing with consecutive 256 frames. The first development model has been employed in the high speed video camera and put in practical use in 2012. By the development of dedicated process technologies, photosensitivity improvement and power consumption reduction were simultaneously achieved, and the performance improved version has been utilized in the commercialized high-speed video camera since 2015 that offers 10 Mfps with ISO16,000 photosensitivity. Due to the improved photosensitivity, clear images can be captured and analyzed even under low light condition, such as under a microscope as well as capturing of UHS light emission phenomena.
Particle displacement tracking applied to air flows
NASA Technical Reports Server (NTRS)
Wernet, Mark P.
1991-01-01
Electronic Particle Image Velocimeter (PIV) techniques offer many advantages over conventional photographic PIV methods such as fast turn around times and simplified data reduction. A new all electronic PIV technique was developed which can measure high speed gas velocities. The Particle Displacement Tracking (PDT) technique employs a single cw laser, small seed particles (1 micron), and a single intensified, gated CCD array frame camera to provide a simple and fast method of obtaining two-dimensional velocity vector maps with unambiguous direction determination. Use of a single CCD camera eliminates registration difficulties encountered when multiple cameras are used to obtain velocity magnitude and direction information. An 80386 PC equipped with a large memory buffer frame-grabber board provides all of the data acquisition and data reduction operations. No array processors of other numerical processing hardware are required. Full video resolution (640x480 pixel) is maintained in the acquired images, providing high resolution video frames of the recorded particle images. The time between data acquisition to display of the velocity vector map is less than 40 sec. The new electronic PDT technique is demonstrated on an air nozzle flow with velocities less than 150 m/s.
Full-scale high-speed ``Edgerton'' retroreflective shadowgraphy of gunshots
NASA Astrophysics Data System (ADS)
Settles, Gary
2005-11-01
Almost 1/2 century ago, H. E. ``Doc'' Edgerton demonstrated a simple and elegant direct-shadowgraph technique for imaging large-scale events like explosions and gunshots. Only a retroreflective screen, flashlamp illumination, and an ordinary view camera were required. Retroreflective shadowgraphy has seen occasional use since then, but its unique combination of large scale, simplicity and portability has barely been tapped. It functions well in environments hostile to most optical diagnostics, such as full-scale outdoor daylight ballistics and explosives testing. Here, shadowgrams cast upon a 2.4 m square retroreflective screen are imaged by a Photron Fastcam APX-RS digital camera that is capable of megapixel image resolution at 3000 frames/sec up to 250,000 frames/sec at lower resolution. Microsecond frame exposures are used to examine the external ballistics of several firearms, including a high-powered rifle, an AK-47 submachine gun, and several pistols and revolvers. Muzzle blast phenomena and the mechanism of gunpowder residue deposition on the shooter's hands are clearly visualized. In particular, observing the firing of a pistol with and without a silencer (suppressor) suggests that some of the muzzle blast energy is converted by the silencer into supersonic jet noise.
a Spatio-Spectral Camera for High Resolution Hyperspectral Imaging
NASA Astrophysics Data System (ADS)
Livens, S.; Pauly, K.; Baeck, P.; Blommaert, J.; Nuyts, D.; Zender, J.; Delauré, B.
2017-08-01
Imaging with a conventional frame camera from a moving remotely piloted aircraft system (RPAS) is by design very inefficient. Less than 1 % of the flying time is used for collecting light. This unused potential can be utilized by an innovative imaging concept, the spatio-spectral camera. The core of the camera is a frame sensor with a large number of hyperspectral filters arranged on the sensor in stepwise lines. It combines the advantages of frame cameras with those of pushbroom cameras. By acquiring images in rapid succession, such a camera can collect detailed hyperspectral information, while retaining the high spatial resolution offered by the sensor. We have developed two versions of a spatio-spectral camera and used them in a variety of conditions. In this paper, we present a summary of three missions with the in-house developed COSI prototype camera (600-900 nm) in the domains of precision agriculture (fungus infection monitoring in experimental wheat plots), horticulture (crop status monitoring to evaluate irrigation management in strawberry fields) and geology (meteorite detection on a grassland field). Additionally, we describe the characteristics of the 2nd generation, commercially available ButterflEYE camera offering extended spectral range (475-925 nm), and we discuss future work.
Park, Jinhyoung; Hu, Changhong; Shung, K Kirk
2011-12-01
A stand-alone front-end system for high-frequency coded excitation imaging was implemented to achieve a wider dynamic range. The system included an arbitrary waveform amplifier, an arbitrary waveform generator, an analog receiver, a motor position interpreter, a motor controller and power supplies. The digitized arbitrary waveforms at a sampling rate of 150 MHz could be programmed and converted to an analog signal. The pulse was subsequently amplified to excite an ultrasound transducer, and the maximum output voltage level achieved was 120 V(pp). The bandwidth of the arbitrary waveform amplifier was from 1 to 70 MHz. The noise figure of the preamplifier was less than 7.7 dB and the bandwidth was 95 MHz. Phantoms and biological tissues were imaged at a frame rate as high as 68 frames per second (fps) to evaluate the performance of the system. During the measurement, 40-MHz lithium niobate (LiNbO(3)) single-element lightweight (<;0.28 g) transducers were utilized. The wire target measure- ment showed that the -6-dB axial resolution of a chirp-coded excitation was 50 μm and lateral resolution was 120 μm. The echo signal-to-noise ratios were found to be 54 and 65 dB for the short burst and coded excitation, respectively. The contrast resolution in a sphere phantom study was estimated to be 24 dB for the chirp-coded excitation and 15 dB for the short burst modes. In an in vivo study, zebrafish and mouse hearts were imaged. Boundaries of the zebrafish heart in the image could be differentiated because of the low-noise operation of the implemented system. In mouse heart images, valves and chambers could be readily visualized with the coded excitation.
Architecture and applications of a high resolution gated SPAD image sensor
Burri, Samuel; Maruyama, Yuki; Michalet, Xavier; Regazzoni, Francesco; Bruschini, Claudio; Charbon, Edoardo
2014-01-01
We present the architecture and three applications of the largest resolution image sensor based on single-photon avalanche diodes (SPADs) published to date. The sensor, fabricated in a high-voltage CMOS process, has a resolution of 512 × 128 pixels and a pitch of 24 μm. The fill-factor of 5% can be increased to 30% with the use of microlenses. For precise control of the exposure and for time-resolved imaging, we use fast global gating signals to define exposure windows as small as 4 ns. The uniformity of the gate edges location is ∼140 ps (FWHM) over the whole array, while in-pixel digital counting enables frame rates as high as 156 kfps. Currently, our camera is used as a highly sensitive sensor with high temporal resolution, for applications ranging from fluorescence lifetime measurements to fluorescence correlation spectroscopy and generation of true random numbers. PMID:25090572
Image sensor with high dynamic range linear output
NASA Technical Reports Server (NTRS)
Yadid-Pecht, Orly (Inventor); Fossum, Eric R. (Inventor)
2007-01-01
Designs and operational methods to increase the dynamic range of image sensors and APS devices in particular by achieving more than one integration times for each pixel thereof. An APS system with more than one column-parallel signal chains for readout are described for maintaining a high frame rate in readout. Each active pixel is sampled for multiple times during a single frame readout, thus resulting in multiple integration times. The operation methods can also be used to obtain multiple integration times for each pixel with an APS design having a single column-parallel signal chain for readout. Furthermore, analog-to-digital conversion of high speed and high resolution can be implemented.
Rapid orthophoto development system.
DOT National Transportation Integrated Search
2013-06-01
The DMC system procured in the project represented state-of-the-art, large-format digital aerial camera systems at the start of : project. DMC is based on the frame camera model, and to achieve large ground coverage with high spatial resolution, the ...
High-Frame-Rate Doppler Ultrasound Using a Repeated Transmit Sequence
Podkowa, Anthony S.; Oelze, Michael L.; Ketterling, Jeffrey A.
2018-01-01
The maximum detectable velocity of high-frame-rate color flow Doppler ultrasound is limited by the imaging frame rate when using coherent compounding techniques. Traditionally, high quality ultrasonic images are produced at a high frame rate via coherent compounding of steered plane wave reconstructions. However, this compounding operation results in an effective downsampling of the slow-time signal, thereby artificially reducing the frame rate. To alleviate this effect, a new transmit sequence is introduced where each transmit angle is repeated in succession. This transmit sequence allows for direct comparison between low resolution, pre-compounded frames at a short time interval in ways that are resistent to sidelobe motion. Use of this transmit sequence increases the maximum detectable velocity by a scale factor of the transmit sequence length. The performance of this new transmit sequence was evaluated using a rotating cylindrical phantom and compared with traditional methods using a 15-MHz linear array transducer. Axial velocity estimates were recorded for a range of ±300 mm/s and compared to the known ground truth. Using these new techniques, the root mean square error was reduced from over 400 mm/s to below 50 mm/s in the high-velocity regime compared to traditional techniques. The standard deviation of the velocity estimate in the same velocity range was reduced from 250 mm/s to 30 mm/s. This result demonstrates the viability of the repeated transmit sequence methods in detecting and quantifying high-velocity flow. PMID:29910966
Schlieren Cinematography of Current Driven Plasma Jet Dynamics
NASA Astrophysics Data System (ADS)
Loebner, Keith; Underwood, Thomas; Cappelli, Mark
2016-10-01
Schlieren cinematography of a pulsed plasma deflagration jet is presented and analyzed. An ultra-high frame rate CMOS camera coupled to a Z-type laser Schlieren apparatus is used to obtain flow-field refractometry data for the continuous flow Z-pinch formed within the plasma deflagration jet. The 10 MHz frame rate for 256 consecutive frames provides high temporal resolution, enabling turbulent fluctuations and plasma instabilities to be visualized over the course of a single pulse (20 μs). The Schlieren signal is radiometrically calibrated to obtain a two dimensional mapping of the refraction angle of the axisymmetric pinch plasma, and this mapping is then Abel inverted to derive the plasma density distribution as a function radius, axial coordinate, and time. Analyses of previously unknown discharge characteristics and comparisons with prior work are discussed.
Boureau, Victor; McLeod, Robert; Mayall, Benjamin; Cooper, David
2018-06-04
In this paper we discuss developments for Lorentz mode or "medium resolution" off-axis electron holography such that it is now routinely possible obtain very high sensitivity phase maps with high spatial resolution whilst maintaining a large field of view. Modifications of the usual Fourier reconstruction procedure have been used to combine series of holograms for sensitivity improvement with a phase-shifting method for doubling the spatial resolution. In the frame of these developments, specific attention is given to the phase standard deviation description and its interaction with the spatial resolution as well as the processing of reference holograms. An experimental study based on Dark-Field Electron Holography (DFEH), using a SiGe/Si multilayer epitaxy sample is compared with theory. The method's efficiency of removing the autocorrelation term during hologram reconstruction is discussed. Software has been written in DigitalMicrograph that can be used to routinely perform these tasks. To illustrate the real improvements made using these methods we show that a strain measurement sensitivity of ± 0.025 % can be achieved with a spatial resolution of 2 nm and ± 0.13 % with a spatial resolution of 1 nm whilst maintaining a useful field of view of 300 nm. In the frame of these measurements a model of strain noise for DFEH has also been developed. Copyright © 2018. Published by Elsevier B.V.
Resolution enhancement of low-quality videos using a high-resolution frame
NASA Astrophysics Data System (ADS)
Pham, Tuan Q.; van Vliet, Lucas J.; Schutte, Klamer
2006-01-01
This paper proposes an example-based Super-Resolution (SR) algorithm of compressed videos in the Discrete Cosine Transform (DCT) domain. Input to the system is a Low-Resolution (LR) compressed video together with a High-Resolution (HR) still image of similar content. Using a training set of corresponding LR-HR pairs of image patches from the HR still image, high-frequency details are transferred from the HR source to the LR video. The DCT-domain algorithm is much faster than example-based SR in spatial domain 6 because of a reduction in search dimensionality, which is a direct result of the compact and uncorrelated DCT representation. Fast searching techniques like tree-structure vector quantization 16 and coherence search1 are also key to the improved efficiency. Preliminary results on MJPEG sequence show promising result of the DCT-domain SR synthesis approach.
NASA Astrophysics Data System (ADS)
Preissner, M.; Murrie, R. P.; Pinar, I.; Werdiger, F.; Carnibella, R. P.; Zosky, G. R.; Fouras, A.; Dubsky, S.
2018-04-01
We have developed an x-ray imaging system for in vivo four-dimensional computed tomography (4DCT) of small animals for pre-clinical lung investigations. Our customized laboratory facility is capable of high resolution in vivo imaging at high frame rates. Characterization using phantoms demonstrate a spatial resolution of slightly below 50 μm at imaging rates of 30 Hz, and the ability to quantify material density differences of at least 3%. We benchmark our system against existing small animal pre-clinical CT scanners using a quality factor that combines spatial resolution, image noise, dose and scan time. In vivo 4DCT images obtained on our system demonstrate resolution of important features such as blood vessels and small airways, of which the smallest discernible were measured as 55–60 μm in cross section. Quantitative analysis of the images demonstrate regional differences in ventilation between injured and healthy lungs.
Development of a high-resolution cavity-beam position monitor
NASA Astrophysics Data System (ADS)
Inoue, Yoichi; Hayano, Hitoshi; Honda, Yosuke; Takatomi, Toshikazu; Tauchi, Toshiaki; Urakawa, Junji; Komamiya, Sachio; Nakamura, Tomoya; Sanuki, Tomoyuki; Kim, Eun-San; Shin, Seung-Hwan; Vogel, Vladimir
2008-06-01
We have developed a high-resolution cavity-beam position monitor (BPM) to be used at the focal point of the ATF2, which is a test beam line that is now being built to demonstrate stable orbit control at ˜nanometer resolution. The design of the cavity structure was optimized for the Accelerator Test Facility (ATF) beam in various ways. For example, the cavity has a rectangular shape in order to isolate two dipole modes in orthogonal directions, and a relatively thin gap that is less sensitive to trajectory inclination. A two stage homodyne mixer with highly sensitive electronics and phase-sensitive detection was also developed. Two BPM blocks, each containing two cavity BPMs, were installed in the existing ATF beam line using a rigid support frame. After testing the basic characteristics, we measured the resolution using three BPMs. The system demonstrated 8.7 nm position resolution over a dynamic range of 5μm.
Performance of a high resolution cavity beam position monitor system
NASA Astrophysics Data System (ADS)
Walston, Sean; Boogert, Stewart; Chung, Carl; Fitsos, Pete; Frisch, Joe; Gronberg, Jeff; Hayano, Hitoshi; Honda, Yosuke; Kolomensky, Yury; Lyapin, Alexey; Malton, Stephen; May, Justin; McCormick, Douglas; Meller, Robert; Miller, David; Orimoto, Toyoko; Ross, Marc; Slater, Mark; Smith, Steve; Smith, Tonee; Terunuma, Nobuhiro; Thomson, Mark; Urakawa, Junji; Vogel, Vladimir; Ward, David; White, Glen
2007-07-01
It has been estimated that an RF cavity Beam Position Monitor (BPM) could provide a position measurement resolution of less than 1 nm. We have developed a high resolution cavity BPM and associated electronics. A triplet comprised of these BPMs was installed in the extraction line of the Accelerator Test Facility (ATF) at the High Energy Accelerator Research Organization (KEK) for testing with its ultra-low emittance beam. The three BPMs were each rigidly mounted inside an alignment frame on six variable-length struts which could be used to move the BPMs in position and angle. We have developed novel methods for extracting the position and tilt information from the BPM signals including a robust calibration algorithm which is immune to beam jitter. To date, we have demonstrated a position resolution of 15.6 nm and a tilt resolution of 2.1 μrad over a dynamic range of approximately ±20 μm.
Barnacle Bill in Super Resolution from Super Panorama
1998-07-03
"Barnacle Bill" is a small rock immediately west-northwest of the Mars Pathfinder lander and was the first rock visited by the Sojourner Rover's alpha proton X-ray spectrometer (APXS) instrument. This image shows super resolution techniques applied to the first APXS target rock, which was never imaged with the rover's forward cameras. Super resolution was applied to help to address questions about the texture of this rock and what it might tell us about its mode of origin. This view of Barnacle Bill was produced by combining the "Super Panorama" frames from the IMP camera. Super resolution was applied to help to address questions about the texture of these rocks and what it might tell us about their mode of origin. The composite color frames that make up this anaglyph were produced for both the right and left eye of the IMP. The composites consist of 7 frames in the right eye and 8 frames in the left eye, taken with different color filters that were enlarged by 500% and then co-added using Adobe Photoshop to produce, in effect, a super-resolution panchromatic frame that is sharper than an individual frame would be. These panchromatic frames were then colorized with the red, green, and blue filtered images from the same sequence. The color balance was adjusted to approximate the true color of Mars. The anaglyph view was produced by combining the left with the right eye color composite frames by assigning the left eye composite view to the red color plane and the right eye composite view to the green and blue color planes (cyan), to produce a stereo anaglyph mosaic. This mosaic can be viewed in 3-D on your computer monitor or in color print form by wearing red-blue 3-D glasses. http://photojournal.jpl.nasa.gov/catalog/PIA01409
Pulsed-neutron imaging by a high-speed camera and center-of-gravity processing
NASA Astrophysics Data System (ADS)
Mochiki, K.; Uragaki, T.; Koide, J.; Kushima, Y.; Kawarabayashi, J.; Taketani, A.; Otake, Y.; Matsumoto, Y.; Su, Y.; Hiroi, K.; Shinohara, T.; Kai, T.
2018-01-01
Pulsed-neutron imaging is attractive technique in the research fields of energy-resolved neutron radiography and RANS (RIKEN) and RADEN (J-PARC/JAEA) are small and large accelerator-driven pulsed-neutron facilities for its imaging, respectively. To overcome the insuficient spatial resolution of the conunting type imaging detectors like μ NID, nGEM and pixelated detectors, camera detectors combined with a neutron color image intensifier were investigated. At RANS center-of-gravity technique was applied to spots image obtained by a CCD camera and the technique was confirmed to be effective for improving spatial resolution. At RADEN a high-frame-rate CMOS camera was used and super resolution technique was applied and it was recognized that the spatial resolution was futhermore improved.
A novel simultaneous streak and framing camera without principle errors
NASA Astrophysics Data System (ADS)
Jingzhen, L.; Fengshan, S.; Ningwen, L.; Xiangdong, G.; Bin, H.; Qingyang, W.; Hongyi, C.; Yi, C.; Xiaowei, L.
2018-02-01
A novel simultaneous streak and framing camera with continuous access, the perfect information of which is far more important for the exact interpretation and precise evaluation of many detonation events and shockwave phenomena, has been developed. The camera with the maximum imaging frequency of 2 × 106 fps and the maximum scanning velocity of 16.3 mm/μs has fine imaging properties which are the eigen resolution of over 40 lp/mm in the temporal direction and over 60 lp/mm in the spatial direction and the framing frequency principle error of zero for framing record, and the maximum time resolving power of 8 ns and the scanning velocity nonuniformity of 0.136%~-0.277% for streak record. The test data have verified the performance of the camera quantitatively. This camera, simultaneously gained frames and streak with parallax-free and identical time base, is characterized by the plane optical system at oblique incidence different from space system, the innovative camera obscura without principle errors, and the high velocity motor driven beryllium-like rotating mirror, made of high strength aluminum alloy with cellular lateral structure. Experiments demonstrate that the camera is very useful and reliable to take high quality pictures of the detonation events.
Single-frame 3D fluorescence microscopy with ultraminiature lensless FlatScope
Adams, Jesse K.; Boominathan, Vivek; Avants, Benjamin W.; Vercosa, Daniel G.; Ye, Fan; Baraniuk, Richard G.; Robinson, Jacob T.; Veeraraghavan, Ashok
2017-01-01
Modern biology increasingly relies on fluorescence microscopy, which is driving demand for smaller, lighter, and cheaper microscopes. However, traditional microscope architectures suffer from a fundamental trade-off: As lenses become smaller, they must either collect less light or image a smaller field of view. To break this fundamental trade-off between device size and performance, we present a new concept for three-dimensional (3D) fluorescence imaging that replaces lenses with an optimized amplitude mask placed a few hundred micrometers above the sensor and an efficient algorithm that can convert a single frame of captured sensor data into high-resolution 3D images. The result is FlatScope: perhaps the world’s tiniest and lightest microscope. FlatScope is a lensless microscope that is scarcely larger than an image sensor (roughly 0.2 g in weight and less than 1 mm thick) and yet able to produce micrometer-resolution, high–frame rate, 3D fluorescence movies covering a total volume of several cubic millimeters. The ability of FlatScope to reconstruct full 3D images from a single frame of captured sensor data allows us to image 3D volumes roughly 40,000 times faster than a laser scanning confocal microscope while providing comparable resolution. We envision that this new flat fluorescence microscopy paradigm will lead to implantable endoscopes that minimize tissue damage, arrays of imagers that cover large areas, and bendable, flexible microscopes that conform to complex topographies. PMID:29226243
Image quality assessment metric for frame accumulated image
NASA Astrophysics Data System (ADS)
Yu, Jianping; Li, Gang; Wang, Shaohui; Lin, Ling
2018-01-01
The medical image quality determines the accuracy of diagnosis, and the gray-scale resolution is an important parameter to measure image quality. But current objective metrics are not very suitable for assessing medical images obtained by frame accumulation technology. Little attention was paid to the gray-scale resolution, basically based on spatial resolution and limited to the 256 level gray scale of the existing display device. Thus, this paper proposes a metric, "mean signal-to-noise ratio" (MSNR) based on signal-to-noise in order to be more reasonable to evaluate frame accumulated medical image quality. We demonstrate its potential application through a series of images under a constant illumination signal. Here, the mean image of enough images was regarded as the reference image. Several groups of images by different frame accumulation and their MSNR were calculated. The results of the experiment show that, compared with other quality assessment methods, the metric is simpler, more effective, and more suitable for assessing frame accumulated images that surpass the gray scale and precision of the original image.
Stellar Populations and Physical Conditions at 100 pc Resolution in a Lensed Galaxy at z 4
NASA Astrophysics Data System (ADS)
Berg, Danielle
2015-10-01
Large surveys of star-forming galaxies at high redshift (z > 1.5) have provided us with a broad understanding of how galaxies assemble and evolve, but the spatial and spectral limitations inherent in observing faint, distant objects mean that many of the physical processes regulating this dynamic evolution are poorly constrained. Much of our most detailed knowledge of the physical conditions in distant galaxies comes from careful studies of gravitationally lensed sources, few of which are at z>3.5. FOR J0332-3557 is a gravitationally lensed galaxy at z 4 for which we and other groups have obtained a total of 37.3 hours of VLT spectroscopy. The rest-frame UV spectrum is notable for its unusual combination of both strong emission lines in the rest-frame UV and strong Lya and interstellar absorption, and for the unusual spatial variation seen in the nebular emission lines, which are less extended than the underlying stellar continuum. We propose high spatial resolution imaging of FOR J0332-3557 with four broadband filters on WFC3, taking advantage of both the HST resolution and the lensing magnification to study star formation and extinction on 100 pc scales. Because the interpretation of our unusual rest-frame UV and optical spectra requires an accurate reddening estimate, combining these observations with ground-based spectroscopy will give the most complete picture to date of chemical evolution in a distant galaxy.
NASA Technical Reports Server (NTRS)
Kilbourne, C. A.; Adams, J. S.; Brekosky, R. P.; Chervenak, J. A.; Chiao, M. P.; Kelley, R. L.; Kelly, D. P.; Porter, F. S.
2011-01-01
The x-ray calorimeter array of the Soft X-ray Spectrometer (SXS) of the Astro-H satellite will incorporate a silicon thermistor array produced during the development of the X-Ray Spectrometer (XRS) of the Suzaku satellite. On XRS, inadequate heat sinking of the array led to several non-ideal effects. The thermal crosstalk, while too small to be confused with x-ray signals, nonetheless contributed a noise term that could be seen as a degradation in energy resolution at high flux. When energy was deposited in the silicon frame around the active elements of the array, such as by a cosmic ray, the resulting pulse in the temperature of the frame resulted in coincident signal pulses on most of the pixels. In orbit, the resolution was found to depend on the particle background rate. In order to minimize these effects on SXS, heat-sinking gold was applied to areas on the front and back of the array die, which was thermally anchored to the gold of its fanout board via gold wire bonds. The thermal conductance from the silicon chip to the fanout board was improved over that of XRS by an order of magnitude. This change was sufficient for essentially eliminating frame events and allowing high-resolution to be attained at much higher counting rates. We will present the improved performance, the measured crosstalk, and the results of the thermal characterization of such arrays.
Theory, implementation and applications of nonstationary Gabor frames
Balazs, P.; Dörfler, M.; Jaillet, F.; Holighaus, N.; Velasco, G.
2011-01-01
Signal analysis with classical Gabor frames leads to a fixed time–frequency resolution over the whole time–frequency plane. To overcome the limitations imposed by this rigidity, we propose an extension of Gabor theory that leads to the construction of frames with time–frequency resolution changing over time or frequency. We describe the construction of the resulting nonstationary Gabor frames and give the explicit formula for the canonical dual frame for a particular case, the painless case. We show that wavelet transforms, constant-Q transforms and more general filter banks may be modeled in the framework of nonstationary Gabor frames. Further, we present the results in the finite-dimensional case, which provides a method for implementing the above-mentioned transforms with perfect reconstruction. Finally, we elaborate on two applications of nonstationary Gabor frames in audio signal processing, namely a method for automatic adaptation to transients and an algorithm for an invertible constant-Q transform. PMID:22267893
A multiresolution halftoning algorithm for progressive display
NASA Astrophysics Data System (ADS)
Mukherjee, Mithun; Sharma, Gaurav
2005-01-01
We describe and implement an algorithmic framework for memory efficient, 'on-the-fly' halftoning in a progressive transmission environment. Instead of a conventional approach which repeatedly recalls the continuous tone image from memory and subsequently halftones it for display, the proposed method achieves significant memory efficiency by storing only the halftoned image and updating it in response to additional information received through progressive transmission. Thus the method requires only a single frame-buffer of bits for storage of the displayed binary image and no additional storage is required for the contone data. The additional image data received through progressive transmission is accommodated through in-place updates of the buffer. The method is thus particularly advantageous for high resolution bi-level displays where it can result in significant savings in memory. The proposed framework is implemented using a suitable multi-resolution, multi-level modification of error diffusion that is motivated by the presence of a single binary frame-buffer. Aggregates of individual display bits constitute the multiple output levels at a given resolution. This creates a natural progression of increasing resolution with decreasing bit-depth.
Adaptive Optics Image Restoration Based on Frame Selection and Multi-frame Blind Deconvolution
NASA Astrophysics Data System (ADS)
Tian, Yu; Rao, Chang-hui; Wei, Kai
Restricted by the observational condition and the hardware, adaptive optics can only make a partial correction of the optical images blurred by atmospheric turbulence. A postprocessing method based on frame selection and multi-frame blind deconvolution is proposed for the restoration of high-resolution adaptive optics images. By frame selection we mean we first make a selection of the degraded (blurred) images for participation in the iterative blind deconvolution calculation, with no need of any a priori knowledge, and with only a positivity constraint. This method has been applied to the restoration of some stellar images observed by the 61-element adaptive optics system installed on the Yunnan Observatory 1.2m telescope. The experimental results indicate that this method can effectively compensate for the residual errors of the adaptive optics system on the image, and the restored image can reach the diffraction-limited quality.
NASA Astrophysics Data System (ADS)
Jerram, P. A.; Fryer, M.; Pratlong, J.; Pike, A.; Walker, A.; Dierickx, B.; Dupont, B.; Defernez, A.
2017-11-01
CCDs have been used for many years for Hyperspectral imaging missions and have been extremely successful. These include the Medium Resolution Imaging Spectrometer (MERIS) [1] on Envisat, the Compact High Resolution Imaging Spectrometer (CHRIS) on Proba and the Ozone Monitoring Instrument operating in the UV spectral region. ESA are also planning a number of further missions that are likely to use CCD technology (Sentinel 3, 4 and 5). However CMOS sensors have a number of advantages which means that they will probably be used for hyperspectral applications in the longer term. There are two main advantages with CMOS sensors: First a hyperspectral image consists of spectral lines with a large difference in intensity; in a frame transfer CCD the faint spectral lines have to be transferred through the part of the imager illuminated by intense lines. This can lead to cross-talk and whilst this problem can be reduced by the use of split frame transfer and faster line rates CMOS sensors do not require a frame transfer and hence inherently will not suffer from this problem. Second, with a CMOS sensor the intense spectral lines can be read multiple times within a frame to give a significant increase in dynamic range. We will describe the design, and initial test of a CMOS sensor for use in hyperspectral applications. This device has been designed to give as high a dynamic range as possible with minimum cross-talk. The sensor has been manufactured on high resistivity epitaxial silicon wafers and is be back-thinned and left relatively thick in order to obtain the maximum quantum efficiency across the entire spectral range
Development of two-framing camera with large format and ultrahigh speed
NASA Astrophysics Data System (ADS)
Jiang, Xiaoguo; Wang, Yuan; Wang, Yi
2012-10-01
High-speed imaging facility is important and necessary for the formation of time-resolved measurement system with multi-framing capability. The framing camera which satisfies the demands of both high speed and large format needs to be specially developed in the ultrahigh speed research field. A two-framing camera system with high sensitivity and time-resolution has been developed and used for the diagnosis of electron beam parameters of Dragon-I linear induction accelerator (LIA). The camera system, which adopts the principle of light beam splitting in the image space behind the lens with long focus length, mainly consists of lens-coupled gated image intensifier, CCD camera and high-speed shutter trigger device based on the programmable integrated circuit. The fastest gating time is about 3 ns, and the interval time between the two frames can be adjusted discretely at the step of 0.5 ns. Both the gating time and the interval time can be tuned to the maximum value of about 1 s independently. Two images with the size of 1024×1024 for each can be captured simultaneously in our developed camera. Besides, this camera system possesses a good linearity, uniform spatial response and an equivalent background illumination as low as 5 electrons/pix/sec, which fully meets the measurement requirements of Dragon-I LIA.
Single-Frame Terrain Mapping Software for Robotic Vehicles
NASA Technical Reports Server (NTRS)
Rankin, Arturo L.
2011-01-01
This software is a component in an unmanned ground vehicle (UGV) perception system that builds compact, single-frame terrain maps for distribution to other systems, such as a world model or an operator control unit, over a local area network (LAN). Each cell in the map encodes an elevation value, terrain classification, object classification, terrain traversability, terrain roughness, and a confidence value into four bytes of memory. The input to this software component is a range image (from a lidar or stereo vision system), and optionally a terrain classification image and an object classification image, both registered to the range image. The single-frame terrain map generates estimates of the support surface elevation, ground cover elevation, and minimum canopy elevation; generates terrain traversability cost; detects low overhangs and high-density obstacles; and can perform geometry-based terrain classification (ground, ground cover, unknown). A new origin is automatically selected for each single-frame terrain map in global coordinates such that it coincides with the corner of a world map cell. That way, single-frame terrain maps correctly line up with the world map, facilitating the merging of map data into the world map. Instead of using 32 bits to store the floating-point elevation for a map cell, the vehicle elevation is assigned to the map origin elevation and reports the change in elevation (from the origin elevation) in terms of the number of discrete steps. The single-frame terrain map elevation resolution is 2 cm. At that resolution, terrain elevation from 20.5 to 20.5 m (with respect to the vehicle's elevation) is encoded into 11 bits. For each four-byte map cell, bits are assigned to encode elevation, terrain roughness, terrain classification, object classification, terrain traversability cost, and a confidence value. The vehicle s current position and orientation, the map origin, and the map cell resolution are all included in a header for each map. The map is compressed into a vector prior to delivery to another system.
Dynamic frequency-domain interferometer for absolute distance measurements with high resolution
NASA Astrophysics Data System (ADS)
Weng, Jidong; Liu, Shenggang; Ma, Heli; Tao, Tianjiong; Wang, Xiang; Liu, Cangli; Tan, Hua
2014-11-01
A unique dynamic frequency-domain interferometer for absolute distance measurement has been developed recently. This paper presents the working principle of the new interferometric system, which uses a photonic crystal fiber to transmit the wide-spectrum light beams and a high-speed streak camera or frame camera to record the interference stripes. Preliminary measurements of harmonic vibrations of a speaker, driven by a radio, and the changes in the tip clearance of a rotating gear wheel show that this new type of interferometer has the ability to perform absolute distance measurements both with high time- and distance-resolution.
Sobieranski, Antonio C; Inci, Fatih; Tekin, H Cumhur; Yuksekkaya, Mehmet; Comunello, Eros; Cobra, Daniel; von Wangenheim, Aldo; Demirci, Utkan
2017-01-01
In this paper, an irregular displacement-based lensless wide-field microscopy imaging platform is presented by combining digital in-line holography and computational pixel super-resolution using multi-frame processing. The samples are illuminated by a nearly coherent illumination system, where the hologram shadows are projected into a complementary metal-oxide semiconductor-based imaging sensor. To increase the resolution, a multi-frame pixel resolution approach is employed to produce a single holographic image from multiple frame observations of the scene, with small planar displacements. Displacements are resolved by a hybrid approach: (i) alignment of the LR images by a fast feature-based registration method, and (ii) fine adjustment of the sub-pixel information using a continuous optimization approach designed to find the global optimum solution. Numerical method for phase-retrieval is applied to decode the signal and reconstruct the morphological details of the analyzed sample. The presented approach was evaluated with various biological samples including sperm and platelets, whose dimensions are in the order of a few microns. The obtained results demonstrate a spatial resolution of 1.55 µm on a field-of-view of ≈30 mm2. PMID:29657866
Lu, Ping; Moya, Jaime M.; Yuan, Renliang; ...
2018-03-01
The delocalization of x-ray signals limits the spatial resolution in atomic-scale elemental mapping by scanning transmission electron microscopy (STEM) using energy-dispersive x-ray spectroscopy (EDS). In this study, using a SrTiO 3 [001] single crystal, we show that the x-ray localization to atomic columns is strongly dependent on crystal thickness, and a thin crystal is critical for improving the spatial resolution in atomic-scale EDS mapping. A single-frame scanning technique is used in this study instead of the multiple-frame technique to avoid peak broadening due to tracking error. The strong thickness dependence is realized by measuring the full width at half maximamore » (FWHM) as well as the peak-to-valley (P/V) ratio of the EDS profiles for Ti K and Sr K+L, obtained at several crystal thicknesses. A FWHM of about 0.16 nm and a P/V ratio of greater than 7.0 are obtained for Ti K for a crystal thickness of less than 20 nm. In conclusion, with increasing crystal thickness, the FWHM and P/V ratio increases and decreases, respectively, indicating the advantage of using a thin crystal for high-resolution EDS mapping.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lu, Ping; Moya, Jaime M.; Yuan, Renliang
The delocalization of x-ray signals limits the spatial resolution in atomic-scale elemental mapping by scanning transmission electron microscopy (STEM) using energy-dispersive x-ray spectroscopy (EDS). In this study, using a SrTiO 3 [001] single crystal, we show that the x-ray localization to atomic columns is strongly dependent on crystal thickness, and a thin crystal is critical for improving the spatial resolution in atomic-scale EDS mapping. A single-frame scanning technique is used in this study instead of the multiple-frame technique to avoid peak broadening due to tracking error. The strong thickness dependence is realized by measuring the full width at half maximamore » (FWHM) as well as the peak-to-valley (P/V) ratio of the EDS profiles for Ti K and Sr K+L, obtained at several crystal thicknesses. A FWHM of about 0.16 nm and a P/V ratio of greater than 7.0 are obtained for Ti K for a crystal thickness of less than 20 nm. In conclusion, with increasing crystal thickness, the FWHM and P/V ratio increases and decreases, respectively, indicating the advantage of using a thin crystal for high-resolution EDS mapping.« less
Lu, Ping; Moya, Jaime M; Yuan, Renliang; Zuo, Jian Min
2018-03-01
The delocalization of x-ray signals limits the spatial resolution in atomic-scale elemental mapping by scanning transmission electron microscopy (STEM) using energy-dispersive x-ray spectroscopy (EDS). In this study, using a SrTiO 3 [001] single crystal, we show that the x-ray localization to atomic columns is strongly dependent on crystal thickness, and a thin crystal is critical for improving the spatial resolution in atomic-scale EDS mapping. A single-frame scanning technique is used in this study instead of the multiple-frame technique to avoid peak broadening due to tracking error. The strong thickness dependence is realized by measuring the full width at half maxima (FWHM) as well as the peak-to-valley (P/V) ratio of the EDS profiles for Ti K and Sr K + L, obtained at several crystal thicknesses. A FWHM of about 0.16 nm and a P/V ratio of greater than 7.0 are obtained for Ti K for a crystal thickness of less than 20 nm. With increasing crystal thickness, the FWHM and P/V ratio increases and decreases, respectively, indicating the advantage of using a thin crystal for high-resolution EDS mapping. Published by Elsevier B.V.
High efficiency video coding for ultrasound video communication in m-health systems.
Panayides, A; Antoniou, Z; Pattichis, M S; Pattichis, C S; Constantinides, A G
2012-01-01
Emerging high efficiency video compression methods and wider availability of wireless network infrastructure will significantly advance existing m-health applications. For medical video communications, the emerging video compression and network standards support low-delay and high-resolution video transmission, at the clinically acquired resolution and frame rates. Such advances are expected to further promote the adoption of m-health systems for remote diagnosis and emergency incidents in daily clinical practice. This paper compares the performance of the emerging high efficiency video coding (HEVC) standard to the current state-of-the-art H.264/AVC standard. The experimental evaluation, based on five atherosclerotic plaque ultrasound videos encoded at QCIF, CIF, and 4CIF resolutions demonstrates that 50% reductions in bitrate requirements is possible for equivalent clinical quality.
All-optical framing photography based on hyperspectral imaging method
NASA Astrophysics Data System (ADS)
Liu, Shouxian; Li, Yu; Li, Zeren; Chen, Guanghua; Peng, Qixian; Lei, Jiangbo; Liu, Jun; Yuan, Shuyun
2017-02-01
We propose and experimentally demonstrate a new all optical-framing photography that uses hyperspectral imaging methods to record a chirped pulse's temporal-spatial information. This proposed method consists of three parts: (1) a chirped laser pulse encodes temporal phenomena onto wavelengths; (2) a lenslet array generates a series of integral pupil images;(3) a dispersive device disperses the integral images at void space of image sensor. Compared with Ultrafast All-Optical Framing Technology(Daniel Frayer,2013,2014) and Sequentially Time All-Optical Mapping Photography( Nakagawa 2014, 2015), our method is convenient to adjust the temporal resolution and to flexibly increase the numbers of frames. Theoretically, the temporal resolution of our scheme is limited by the amount of dispersion that is added to a Fourier transform limited femtosecond laser pulse. Correspondingly, the optimal number of frames is decided by the ratio of the observational time window to the temporal resolution, and the effective pixels of each frame are mostly limited by the dimensions M×N of the lenslet array. For example, if a 40fs Fourier transform limited femtosecond pulse is stretched to 10ps, a CCD camera with 2048×3072 pixels can record 15 framing images with temporal resolution of 650fs and image size of 100×100 pixels. As spectrometer structure, our recording part has another advantage that not only amplitude images but also frequency domain interferograms can be imaged. Therefore, it is comparatively easy to capture fast dynamics in the refractive index change of materials. A further dynamic experiment is being conducted.
Integrated GNSS Attitude Determination and Positioning for Direct Geo-Referencing
Nadarajah, Nandakumaran; Paffenholz, Jens-André; Teunissen, Peter J. G.
2014-01-01
Direct geo-referencing is an efficient methodology for the fast acquisition of 3D spatial data. It requires the fusion of spatial data acquisition sensors with navigation sensors, such as Global Navigation Satellite System (GNSS) receivers. In this contribution, we consider an integrated GNSS navigation system to provide estimates of the position and attitude (orientation) of a 3D laser scanner. The proposed multi-sensor system (MSS) consists of multiple GNSS antennas rigidly mounted on the frame of a rotating laser scanner and a reference GNSS station with known coordinates. Precise GNSS navigation requires the resolution of the carrier phase ambiguities. The proposed method uses the multivariate constrained integer least-squares (MC-LAMBDA) method for the estimation of rotating frame ambiguities and attitude angles. MC-LAMBDA makes use of the known antenna geometry to strengthen the underlying attitude model and, hence, to enhance the reliability of rotating frame ambiguity resolution and attitude determination. The reliable estimation of rotating frame ambiguities is consequently utilized to enhance the relative positioning of the rotating frame with respect to the reference station. This integrated (array-aided) method improves ambiguity resolution, as well as positioning accuracy between the rotating frame and the reference station. Numerical analyses of GNSS data from a real-data campaign confirm the improved performance of the proposed method over the existing method. In particular, the integrated method yields reliable ambiguity resolution and reduces position standard deviation by a factor of about 0.8, matching the theoretical gain of 3/4 for two antennas on the rotating frame and a single antenna at the reference station. PMID:25036330
Integrated GNSS attitude determination and positioning for direct geo-referencing.
Nadarajah, Nandakumaran; Paffenholz, Jens-André; Teunissen, Peter J G
2014-07-17
Direct geo-referencing is an efficient methodology for the fast acquisition of 3D spatial data. It requires the fusion of spatial data acquisition sensors with navigation sensors, such as Global Navigation Satellite System (GNSS) receivers. In this contribution, we consider an integrated GNSS navigation system to provide estimates of the position and attitude (orientation) of a 3D laser scanner. The proposed multi-sensor system (MSS) consists of multiple GNSS antennas rigidly mounted on the frame of a rotating laser scanner and a reference GNSS station with known coordinates. Precise GNSS navigation requires the resolution of the carrier phase ambiguities. The proposed method uses the multivariate constrained integer least-squares (MC-LAMBDA) method for the estimation of rotating frame ambiguities and attitude angles. MC-LAMBDA makes use of the known antenna geometry to strengthen the underlying attitude model and, hence, to enhance the reliability of rotating frame ambiguity resolution and attitude determination. The reliable estimation of rotating frame ambiguities is consequently utilized to enhance the relative positioning of the rotating frame with respect to the reference station. This integrated (array-aided) method improves ambiguity resolution, as well as positioning accuracy between the rotating frame and the reference station. Numerical analyses of GNSS data from a real-data campaign confirm the improved performance of the proposed method over the existing method. In particular, the integrated method yields reliable ambiguity resolution and reduces position standard deviation by a factor of about 0:8, matching the theoretical gain of √ 3/4 for two antennas on the rotating frame and a single antenna at the reference station.
Improved optical flow motion estimation for digital image stabilization
NASA Astrophysics Data System (ADS)
Lai, Lijun; Xu, Zhiyong; Zhang, Xuyao
2015-11-01
Optical flow is the instantaneous motion vector at each pixel in the image frame at a time instant. The gradient-based approach for optical flow computation can't work well when the video motion is too large. To alleviate such problem, we incorporate this algorithm into a pyramid multi-resolution coarse-to-fine search strategy. Using pyramid strategy to obtain multi-resolution images; Using iterative relationship from the highest level to the lowest level to obtain inter-frames' affine parameters; Subsequence frames compensate back to the first frame to obtain stabilized sequence. The experiment results demonstrate that the promoted method has good performance in global motion estimation.
Chen, Yuling; Lou, Yang; Yen, Jesse
2017-07-01
During conventional ultrasound imaging, the need for multiple transmissions for one image and the time of flight for a desired imaging depth limit the frame rate of the system. Using a single plane wave pulse during each transmission followed by parallel receive processing allows for high frame rate imaging. However, image quality is degraded because of the lack of transmit focusing. Beamforming by spatial matched filtering (SMF) is a promising method which focuses ultrasonic energy using spatial filters constructed from the transmit-receive impulse response of the system. Studies by other researchers have shown that SMF beamforming can provide dynamic transmit-receive focusing throughout the field of view. In this paper, we apply SMF beamforming to plane wave transmissions (PWTs) to achieve both dynamic transmit-receive focusing at all imaging depths and high imaging frame rate (>5000 frames per second). We demonstrated the capability of the combined method (PWT + SMF) of achieving two-way focusing mathematically through analysis based on the narrowband Rayleigh-Sommerfeld diffraction theory. Moreover, the broadband performance of PWT + SMF was quantified in terms of lateral resolution and contrast from both computer simulations and experimental data. Results were compared between SMF beamforming and conventional delay-and-sum (DAS) beamforming in both simulations and experiments. At an imaging depth of 40 mm, simulation results showed a 29% lateral resolution improvement and a 160% contrast improvement with PWT + SMF. These improvements were 17% and 48% for experimental data with noise.
Real-time image sequence segmentation using curve evolution
NASA Astrophysics Data System (ADS)
Zhang, Jun; Liu, Weisong
2001-04-01
In this paper, we describe a novel approach to image sequence segmentation and its real-time implementation. This approach uses the 3D structure tensor to produce a more robust frame difference signal and uses curve evolution to extract whole objects. Our algorithm is implemented on a standard PC running the Windows operating system with video capture from a USB camera that is a standard Windows video capture device. Using the Windows standard video I/O functionalities, our segmentation software is highly portable and easy to maintain and upgrade. In its current implementation on a Pentium 400, the system can perform segmentation at 5 frames/sec with a frame resolution of 160 by 120.
NASA Technical Reports Server (NTRS)
1992-01-01
The IMAX camera system is used to record on-orbit activities of interest to the public. Because of the extremely high resolution of the IMAX camera, projector, and audio systems, the audience is afforded a motion picture experience unlike any other. IMAX and OMNIMAX motion picture systems were designed to create motion picture images of superior quality and audience impact. The IMAX camera is a 65 mm, single lens, reflex viewing design with a 15 perforation per frame horizontal pull across. The frame size is 2.06 x 2.77 inches. Film travels through the camera at a rate of 336 feet per minute when the camera is running at the standard 24 frames/sec.
Norbert, M.A.; Yale, O.
1992-04-28
A large effective-aperture, low-cost optical telescope with diffraction-limited resolution enables ground-based observation of near-earth space objects. The telescope has a non-redundant, thinned-aperture array in a center-mount, single-structure space frame. It employes speckle interferometric imaging to achieve diffraction-limited resolution. The signal-to-noise ratio problem is mitigated by moving the wavelength of operation to the near-IR, and the image is sensed by a Silicon CCD. The steerable, single-structure array presents a constant pupil. The center-mount, radar-like mount enables low-earth orbit space objects to be tracked as well as increases stiffness of the space frame. In the preferred embodiment, the array has elemental telescopes with subaperture of 2.1 m in a circle-of-nine configuration. The telescope array has an effective aperture of 12 m which provides a diffraction-limited resolution of 0.02 arc seconds. Pathlength matching of the telescope array is maintained by a electro-optical system employing laser metrology. Speckle imaging relaxes pathlength matching tolerance by one order of magnitude as compared to phased arrays. Many features of the telescope contribute to substantial reduction in costs. These include eliminating the conventional protective dome and reducing on-site construction activities. The cost of the telescope scales with the first power of the aperture rather than its third power as in conventional telescopes. 15 figs.
Norbert, Massie A.; Yale, Oster
1992-01-01
A large effective-aperture, low-cost optical telescope with diffraction-limited resolution enables ground-based observation of near-earth space objects. The telescope has a non-redundant, thinned-aperture array in a center-mount, single-structure space frame. It employes speckle interferometric imaging to achieve diffraction-limited resolution. The signal-to-noise ratio problem is mitigated by moving the wavelength of operation to the near-IR, and the image is sensed by a Silicon CCD. The steerable, single-structure array presents a constant pupil. The center-mount, radar-like mount enables low-earth orbit space objects to be tracked as well as increases stiffness of the space frame. In the preferred embodiment, the array has elemental telescopes with subaperture of 2.1 m in a circle-of-nine configuration. The telescope array has an effective aperture of 12 m which provides a diffraction-limited resolution of 0.02 arc seconds. Pathlength matching of the telescope array is maintained by a electro-optical system employing laser metrology. Speckle imaging relaxes pathlength matching tolerance by one order of magnitude as compared to phased arrays. Many features of the telescope contribute to substantial reduction in costs. These include eliminating the conventional protective dome and reducing on-site construction activities. The cost of the telescope scales with the first power of the aperture rather than its third power as in conventional telescopes.
High-speed multi-exposure laser speckle contrast imaging with a single-photon counting camera
Dragojević, Tanja; Bronzi, Danilo; Varma, Hari M.; Valdes, Claudia P.; Castellvi, Clara; Villa, Federica; Tosi, Alberto; Justicia, Carles; Zappa, Franco; Durduran, Turgut
2015-01-01
Laser speckle contrast imaging (LSCI) has emerged as a valuable tool for cerebral blood flow (CBF) imaging. We present a multi-exposure laser speckle imaging (MESI) method which uses a high-frame rate acquisition with a negligible inter-frame dead time to mimic multiple exposures in a single-shot acquisition series. Our approach takes advantage of the noise-free readout and high-sensitivity of a complementary metal-oxide-semiconductor (CMOS) single-photon avalanche diode (SPAD) array to provide real-time speckle contrast measurement with high temporal resolution and accuracy. To demonstrate its feasibility, we provide comparisons between in vivo measurements with both the standard and the new approach performed on a mouse brain, in identical conditions. PMID:26309751
Research on the underwater target imaging based on the streak tube laser lidar
NASA Astrophysics Data System (ADS)
Cui, Zihao; Tian, Zhaoshuo; Zhang, Yanchao; Bi, Zongjie; Yang, Gang; Gu, Erdan
2018-03-01
A high frame rate streak tube imaging lidar (STIL) for real-time 3D imaging of underwater targets is presented in this paper. The system uses 532nm pulse laser as the light source, the maximum repetition rate is 120Hz, and the pulse width is 8ns. LabVIEW platform is used in the system, the system control, synchronous image acquisition, 3D data processing and display are realized through PC. 3D imaging experiment of underwater target is carried out in a flume with attenuation coefficient of 0.2, and the images of different depth and different material targets are obtained, the imaging frame rate is 100Hz, and the maximum detection depth is 31m. For an underwater target with a distance of 22m, the high resolution 3D image real-time acquisition is realized with range resolution of 1cm and space resolution of 0.3cm, the spatial relationship of the targets can be clearly identified by the image. The experimental results show that STIL has a good application prospect in underwater terrain detection, underwater search and rescue, and other fields.
High-frame-rate imaging of biological samples with optoacoustic micro-tomography
NASA Astrophysics Data System (ADS)
Deán-Ben, X. Luís.; López-Schier, Hernán.; Razansky, Daniel
2018-02-01
Optical microscopy remains a major workhorse in biological discovery despite the fact that light scattering limits its applicability to depths of ˜ 1 mm in scattering tissues. Optoacoustic imaging has been shown to overcome this barrier by resolving optical absorption with microscopic resolution in significantly deeper regions. Yet, the time domain is paramount for the observation of biological dynamics in living systems that exhibit fast motion. Commonly, acquisition of microscopy data involves raster scanning across the imaged volume, which significantly limits temporal resolution in 3D. To overcome these limitations, we have devised a fast optoacoustic micro-tomography (OMT) approach based on simultaneous acquisition of 3D image data with a high-density hemispherical ultrasound array having effective detection bandwidth around 25 MHz. We performed experiments by imaging tissue-mimicking phantoms and zebrafish larvae, demonstrating that OMT can provide nearly cellular resolution and imaging speed of 100 volumetric frames per second. As opposed to other optical microscopy techniques, OMT is a hybrid method that resolves optical absorption contrast acoustically using unfocused light excitation. Thus, no penetration barriers are imposed by light scattering in deep tissues, suggesting it as a powerful approach for multi-scale functional and molecular imaging applications.
NASA Astrophysics Data System (ADS)
Cui, Bo-chuan; Wang, Jian-li; Yao, Kai-nan; Chen, Tao
2018-03-01
An approach to measure a high-dynamic two-dimensional (2D) temperature field using a high-speed quadriwave lateral shearing interferometer (QWLSI) is proposed. The detailed theoretical derivation to express the wavefront reconstruct principle of the proposed method is presented. The comparison experiment with thermocouples shows that the temperature field measurement using QWLSI has a precision of ±0.5 °C. An experiment for measuring the highdynamic temperature field generated by an electrical heater is carried out. A 200 frame rate temperature field video with 512 × 512 resolution is obtained finally. Experimental results show that the temperature field measurement system using a QWLSI has the advantage of high sensitivity and high resolution.
Immersive video for virtual tourism
NASA Astrophysics Data System (ADS)
Hernandez, Luis A.; Taibo, Javier; Seoane, Antonio J.
2001-11-01
This paper describes a new panoramic, 360 degree(s) video system and its use in a real application for virtual tourism. The development of this system has required to design new hardware for multi-camera recording, and software for video processing in order to elaborate the panorama frames and to playback the resulting high resolution video footage on a regular PC. The system makes use of new VR display hardware, such as WindowVR, in order to make the view dependent on the viewer's spatial orientation and so enhance immersiveness. There are very few examples of similar technologies and the existing ones are extremely expensive and/or impossible to be implemented on personal computers with acceptable quality. The idea of the system starts from the concept of Panorama picture, developed in technologies such as QuickTimeVR. This idea is extended to the concept of panorama frame that leads to panorama video. However, many problems are to be solved to implement this simple scheme. Data acquisition involves simultaneously footage recording in every direction, and latter processing to convert every set of frames in a single high resolution panorama frame. Since there is no common hardware capable of 4096x512 video playback at 25 fps rate, it must be stripped in smaller pieces which the system must manage to get the right frames of the right parts as the user movement demands it. As the system must be immersive, the physical interface to watch the 360 degree(s) video is a WindowVR, that is, a flat screen with an orientation tracker that the user holds in his hands, moving it like if it were a virtual window through which the city and its activity is being shown.
NASA Astrophysics Data System (ADS)
Huang, Feng; Sun, Lifeng; Zhong, Yuzhuo
2006-01-01
Robust transmission of live video over ad hoc wireless networks presents new challenges: high bandwidth requirements are coupled with delay constraints; even a single packet loss causes error propagation until a complete video frame is coded in the intra-mode; ad hoc wireless networks suffer from bursty packet losses that drastically degrade the viewing experience. Accordingly, we propose a novel UMD coder capable of quickly recovering from losses and ensuring continuous playout. It uses 'peg' frames to prevent error propagation in the High-Resolution (HR) description and improve the robustness of key frames. The Low-Resolution (LR) coder works independent of the HR one, but they can also help each other recover from losses. Like many UMD coders, our UMD coder is drift-free, disruption-tolerant and able to make good use of the asymmetric available bandwidths of multiple paths. The simulation results under different conditions show that the proposed UMD coder has the highest decoded quality and lowest probability of pause when compared with concurrent UMDC techniques. The coder also has a comparable decoded quality, lower startup delay and lower probability of pause than a state-of-the-art FEC-based scheme. To provide robustness for video multicast applications, we propose non-end-to-end UMDC-based video distribution over a multi-tree multicast network. The multiplicity of parents decorrelates losses and the non-end-to-end feature increases the throughput of UMDC video data. We deploy an application-level service of LR description reconstruction in some intermediate nodes of the LR multicast tree. The principle behind this is to reconstruct the disrupted LR frames by the correctly received HR frames. As a result, the viewing experience at the downstream nodes benefits from the protection reconstruction at the upstream nodes.
Joint denoising, demosaicing, and chromatic aberration correction for UHD video
NASA Astrophysics Data System (ADS)
Jovanov, Ljubomir; Philips, Wilfried; Damstra, Klaas Jan; Ellenbroek, Frank
2017-09-01
High-resolution video capture is crucial for numerous applications such as surveillance, security, industrial inspection, medical imaging and digital entertainment. In the last two decades, we are witnessing a dramatic increase of the spatial resolution and the maximal frame rate of video capturing devices. In order to achieve further resolution increase, numerous challenges will be facing us. Due to the reduced size of the pixel, the amount of light also reduces, leading to the increased noise level. Moreover, the reduced pixel size makes the lens imprecisions more pronounced, which especially applies to chromatic aberrations. Even in the case when high quality lenses are used some chromatic aberration artefacts will remain. Next, noise level additionally increases due to the higher frame rates. To reduce the complexity and the price of the camera, one sensor captures all three colors, by relying on Color Filter Arrays. In order to obtain full resolution color image, missing color components have to be interpolated, i.e. demosaicked, which is more challenging than in the case of lower resolution, due to the increased noise and aberrations. In this paper, we propose a new method, which jointly performs chromatic aberration correction, denoising and demosaicking. By jointly performing the reduction of all artefacts, we are reducing the overall complexity of the system and the introduction of new artefacts. In order to reduce possible flicker we also perform temporal video enhancement. We evaluate the proposed method on a number of publicly available UHD sequences and on sequences recorded in our studio.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhao Bo; Zhao Wei
2008-05-15
In breast tomosynthesis a rapid sequence of N images is acquired when the x-ray tube sweeps through different angular views with respect to the breast. Since the total dose to the breast is kept the same as that in regular mammography, the exposure used for each image of tomosynthesis is 1/N. The low dose and high frame rate pose a tremendous challenge to the imaging performance of digital mammography detectors. The purpose of the present work is to investigate the detector performance in different operational modes designed for tomosynthesis acquisition, e.g., binning or full resolution readout, the range of viewmore » angles, and the number of views N. A prototype breast tomosynthesis system with a nominal angular range of {+-}25 deg. was used in our investigation. The system was equipped with an amorphous selenium (a-Se) full field digital mammography detector with pixel size of 85 {mu}m. The detector can be read out in full resolution or 2x1 binning (binning in the tube travel direction). The focal spot blur due to continuous tube travel was measured for different acquisition geometries, and it was found that pixel binning, instead of focal spot blur, dominates the detector modulation transfer function (MTF). The noise power spectrum (NPS) and detective quantum efficiency (DQE) of the detector were measured with the exposure range of 0.4-6 mR, which is relevant to the low dose used in tomosynthesis. It was found that DQE at 0.4 mR is only 20% less than that at highest exposure for both detector readout modes. The detector temporal performance was categorized as lag and ghosting, both of which were measured as a function of x-ray exposure. The first frame lags were 8% and 4%, respectively, for binning and full resolution mode. Ghosting is negligible and independent of the frame rate. The results showed that the detector performance is x-ray quantum noise limited at the low exposures used in each view of tomosynthesis, and the temporal performance at high frame rate (up to 2 frames per second) is adequate for tomosynthesis.« less
High-speed imaging using 3CCD camera and multi-color LED flashes
NASA Astrophysics Data System (ADS)
Hijazi, Ala; Friedl, Alexander; Cierpka, Christian; Kähler, Christian; Madhavan, Vis
2017-11-01
This paper demonstrates the possibility of capturing full-resolution, high-speed image sequences using a regular 3CCD color camera in conjunction with high-power light emitting diodes of three different colors. This is achieved using a novel approach, referred to as spectral-shuttering, where a high-speed image sequence is captured using short duration light pulses of different colors that are sent consecutively in very close succession. The work presented in this paper demonstrates the feasibility of configuring a high-speed camera system using low cost and readily available off-the-shelf components. This camera can be used for recording six-frame sequences at frame rates up to 20 kHz or three-frame sequences at even higher frame rates. Both color crosstalk and spatial matching between the different channels of the camera are found to be within acceptable limits. A small amount of magnification difference between the different channels is found and a simple calibration procedure for correcting the images is introduced. The images captured using the approach described here are of good quality to be used for obtaining full-field quantitative information using techniques such as digital image correlation and particle image velocimetry. A sequence of six high-speed images of a bubble splash recorded at 400 Hz is presented as a demonstration.
NASA Astrophysics Data System (ADS)
Kopeikin, Sergei; Xie, Yi
2010-11-01
We introduce the Jacobi coordinates adopted to the advanced theoretical analysis of the relativistic Celestial Mechanics of the Earth-Moon system. Theoretical derivation utilizes the relativistic resolutions on reference frames adopted by the International Astronomical Union (IAU) in 2000. The resolutions assume that the Solar System is isolated and space-time is asymptotically flat at infinity and the primary reference frame covers the entire space-time, has its origin at the Solar System barycenter (SSB) with spatial axes stretching up to infinity. The SSB frame is not rotating with respect to a set of distant quasars that are assumed to be at rest on the sky forming the International Celestial Reference Frame (ICRF). The second reference frame has its origin at the Earth-Moon barycenter (EMB). The EMB frame is locally inertial and is not rotating dynamically in the sense that equation of motion of a test particle moving with respect to the EMB frame, does not contain the Coriolis and centripetal forces. Two other local frames—geocentric and selenocentric—have their origins at the center of mass of Earth and Moon respectively and do not rotate dynamically. Each local frame is subject to the geodetic precession both with respect to other local frames and with respect to the ICRF because of their relative motion with respect to each other. Theoretical advantage of the dynamically non-rotating local frames is in a more simple mathematical description of the metric tensor and relative equations of motion of the Moon with respect to Earth. Each local frame can be converted to kinematically non-rotating one after alignment with the axes of ICRF by applying the matrix of the relativistic precession as recommended by the IAU resolutions. The set of one global and three local frames is introduced in order to decouple physical effects of gravity from the gauge-dependent effects in the equations of relative motion of the Moon with respect to Earth.
NASA Astrophysics Data System (ADS)
Schaeper, M.; Schmidt, R.; Kostbade, R.; Damaschke, N.; Gimsa, J.
2016-07-01
Circular spatial filtering velocimetry (CSFV) was tested during the microscopic registration of the individual rotations of baker’s yeast cells. Their frequency-dependent rotation (electrorotation; ER) was induced in rotating electric fields, which were generated in a glass chip chamber with four electrodes (600 μm tip-to-tip distance). The electrodes were driven with sinusoidal quadrature signals of 5 or 8 V PP with frequencies up to 3 MHz. The observed cell rotation was of the order of 1-100 s per revolution. At each measuring frequency, the independent rotations of up to 20 cells were simultaneously recorded with a high-speed camera. CSFV was software-implemented using circular spatial filters with harmonic gratings. ER was proportional to the phase shift between the values of the spatial filtering signal of consecutive frames. ER spectra obtained by CSFV from the rotation velocities at different ER-field frequencies agreed well with manual measurements and theoretical spectra. Oscillations in the rotation velocity of a single cell in the elliptically polarized field near an electrode, which were resolved by CSFV, could not be visually discerned. ER step responses after field-on were recorded at 2500 frames per second. Analysis proved the high temporal resolution of CSFV and revealed a largely linear torque-friction relation during the acceleration phase of ER. Future applications of CSFV will allow for the simple and cheap automated high-resolution analysis of rotational movements where mechanical detection has too low a resolution or is not possible, e.g. in polluted environments or for gas and fluid vortices, microscopic objects, etc.
NASA Astrophysics Data System (ADS)
Faber, T. L.; Raghunath, N.; Tudorascu, D.; Votaw, J. R.
2009-02-01
Image quality is significantly degraded even by small amounts of patient motion in very high-resolution PET scanners. Existing correction methods that use known patient motion obtained from tracking devices either require multi-frame acquisitions, detailed knowledge of the scanner, or specialized reconstruction algorithms. A deconvolution algorithm has been developed that alleviates these drawbacks by using the reconstructed image to estimate the original non-blurred image using maximum likelihood estimation maximization (MLEM) techniques. A high-resolution digital phantom was created by shape-based interpolation of the digital Hoffman brain phantom. Three different sets of 20 movements were applied to the phantom. For each frame of the motion, sinograms with attenuation and three levels of noise were simulated and then reconstructed using filtered backprojection. The average of the 20 frames was considered the motion blurred image, which was restored with the deconvolution algorithm. After correction, contrast increased from a mean of 2.0, 1.8 and 1.4 in the motion blurred images, for the three increasing amounts of movement, to a mean of 2.5, 2.4 and 2.2. Mean error was reduced by an average of 55% with motion correction. In conclusion, deconvolution can be used for correction of motion blur when subject motion is known.
NASA Astrophysics Data System (ADS)
Caragiulo, P.; Dragone, A.; Markovic, B.; Herbst, R.; Nishimura, K.; Reese, B.; Herrmann, S.; Hart, P.; Blaj, G.; Segal, J.; Tomada, A.; Hasi, J.; Carini, G.; Kenney, C.; Haller, G.
2015-05-01
ePix10k is a variant of a novel class of integrating pixel ASICs architectures optimized for the processing of signals in second generation LINAC Coherent Light Source (LCLS) X-Ray cameras. The ASIC is optimized for high dynamic range application requiring high spatial resolution and fast frame rates. ePix ASICs are based on a common platform composed of a random access analog matrix of pixel with global shutter, fast parallel column readout, and dedicated sigma-delta analog to digital converters per column. The ePix10k variant has 100um×100um pixels arranged in a 176×192 matrix, a resolution of 140e- r.m.s. and a signal range of 3.5pC (10k photons at 8keV). In its final version it will be able to sustain a frame rate of 2kHz. A first prototype has been fabricated and characterized. Performance in terms of noise, linearity, uniformity, cross-talk, together with preliminary measurements with bump bonded sensors are reported here.
Three years of ULTRASPEC at the Thai 2.4-m telescope: Capabilities and scientific highlights
NASA Astrophysics Data System (ADS)
Yadav, Ram Kesh; Richichi, Andrea; Irawati, Puji; Dhillon, Vikram Singh; Marsh, Thomas R.; Soonthornthum, Boonrucksar
2018-04-01
High temporal resolution observations enable the study of rapid phenomena such as the flux variations in binary system objects, e.g. cataclysmic variables, compact binary systems, the flux variations in young star clusters, stellar occultations and more. The 2.4-m Thai National Telescope (TNT) is ideally suited for this niche research, being the largest facility in Southeast Asia and being equipped with ULTRASPEC, a high-speed imager based on a low-noise frame transfer electron-multiplying CCD. In the sub-window mode, ULTRASPEC can record uninterrupted sequences with frame rates as fast as few milliseconds. We present some of the key results obtained in the area of high time resolution with ULTRASPEC. We also present the results of a recent worldwide campaign to observe the current series of lunar occultations of Aldebaran (α Tauri) carried out in close collaboration with the Devasthal facilities, the out-of-eclipse variations on the post common-envelope system J1021+1744, and pre-main-sequence variables in young open cluster Stock 8.
NASA Astrophysics Data System (ADS)
Pi, Shiqiang; Liu, Wenzhong; Jiang, Tao
2018-03-01
The magnetic transparency of biological tissue allows the magnetic nanoparticle (MNP) to be a promising functional sensor and contrast agent. The complex susceptibility of MNPs, strongly influenced by particle concentration, excitation magnetic field and their surrounding microenvironment, provides significant implications for biomedical applications. Therefore, magnetic susceptibility imaging of high spatial resolution will give more detailed information during the process of MNP-aided diagnosis and therapy. In this study, we present a novel spatial magnetic susceptibility extraction method for MNPs under a gradient magnetic field, a low-frequency drive magnetic field, and a weak strength high-frequency magnetic field. Based on this novel method, a magnetic particle susceptibility imaging (MPSI) of millimeter-level spatial resolution (<3 mm) was achieved using our homemade imaging system. Corroborated by the experimental results, the MPSI shows real-time (1 s per frame acquisition) and quantitative abilities, and isotropic high resolution.
High frame rate imaging systems developed in Northwest Institute of Nuclear Technology
NASA Astrophysics Data System (ADS)
Li, Binkang; Wang, Kuilu; Guo, Mingan; Ruan, Linbo; Zhang, Haibing; Yang, Shaohua; Feng, Bing; Sun, Fengrong; Chen, Yanli
2007-01-01
This paper presents high frame rate imaging systems developed in Northwest Institute of Nuclear Technology in recent years. Three types of imaging systems are included. The first type of system utilizes EG&G RETICON Photodiode Array (PDA) RA100A as the image sensor, which can work at up to 1000 frame per second (fps). Besides working continuously, the PDA system is also designed to switch to capture flash light event working mode. A specific time sequence is designed to satisfy this request. The camera image data can be transmitted to remote area by coaxial or optic fiber cable and then be stored. The second type of imaging system utilizes PHOTOBIT Complementary Metal Oxygen Semiconductor (CMOS) PB-MV13 as the image sensor, which has a high resolution of 1280 (H) ×1024 (V) pixels per frame. The CMOS system can operate at up to 500fps in full frame and 4000fps partially. The prototype scheme of the system is presented. The third type of imaging systems adopts charge coupled device (CCD) as the imagers. MINTRON MTV-1881EX, DALSA CA-D1 and CA-D6 camera head are used in the systems development. The features comparison of the RA100A, PB-MV13, and CA-D6 based systems are given in the end.
Framing and the health policy process: a scoping review.
Koon, Adam D; Hawkins, Benjamin; Mayhew, Susannah H
2016-07-01
Framing research seeks to understand the forces that shape human behaviour in the policy process. It assumes that policy is a social construct and can be cast in a variety of ways to imply multiple legitimate value considerations. Frames provide the cognitive means of making sense of the social world, but discordance among them forms the basis of policy contestation. Framing, as both theory and method, has proven to generate considerable insight into the nature of policy debates in a variety of disciplines. Despite its salience for understanding health policy debates; however, little is known about the ways frames influence the health policy process. A scoping review using the Arksey and O'Malley framework was conducted. The literature on framing in the health sector was reviewed using nine health and social science databases. Articles were included that explicitly reported theory and methods used, data source(s), at least one frame, frame sponsor and evidence of a given frame's effect on the health policy process. A total of 52 articles, from 1996 to 2014, and representing 12 countries, were identified. Much of the research came from the policy studies/political science literature (n = 17) and used a constructivist epistemology. The term 'frame' was used as a label to describe a variety of ideas, packaged as values, social problems, metaphors or arguments. Frames were characterized at various levels of abstraction ranging from general ideological orientations to specific policy positions. Most articles presented multiple frames and showed how actors advocated for them in a highly contested political process. Framing is increasingly an important, yet overlooked aspect of the policy process. Further analysis on frames, framing processes and frame conflict can help researchers and policymakers to understand opaque and highly charged policy issues, which may facilitate the resolution of protracted policy controversies. © The Author 2016. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.
Near-affine-invariant texture learning for lung tissue analysis using isotropic wavelet frames.
Depeursinge, Adrien; Van de Ville, Dimitri; Platon, Alexandra; Geissbuhler, Antoine; Poletti, Pierre-Alexandre; Müller, Henning
2012-07-01
We propose near-affine-invariant texture descriptors derived from isotropic wavelet frames for the characterization of lung tissue patterns in high-resolution computed tomography (HRCT) imaging. Affine invariance is desirable to enable learning of nondeterministic textures without a priori localizations, orientations, or sizes. When combined with complementary gray-level histograms, the proposed method allows a global classification accuracy of 76.9% with balanced precision among five classes of lung tissue using a leave-one-patient-out cross validation, in accordance with clinical practice.
DOE Office of Scientific and Technical Information (OSTI.GOV)
McCowan, P. M., E-mail: pmccowan@cancercare.mb.ca; McCurdy, B. M. C.; Medical Physics Department, CancerCare Manitoba, 675 McDermot Avenue, Winnipeg, Manitoba R3E 0V9
Purpose: The in vivo 3D dose delivered to a patient during volumetric modulated arc therapy (VMAT) delivery can be calculated using electronic portal imaging device (EPID) images. These images must be acquired in cine-mode (i.e., “movie” mode) in order to capture the time-dependent delivery information. The angle subtended by each cine-mode EPID image during an arc can be changed via the frame averaging number selected within the image acquisition software. A large frame average number will decrease the EPID’s angular resolution and will result in a decrease in the accuracy of the dose information contained within each image. Alternatively, lessmore » EPID images acquired per delivery will decrease the overall 3D patient dose calculation time, which is appealing for large-scale clinical implementation. Therefore, the purpose of this study was to determine the optimal frame average value per EPID image, defined as the highest frame averaging that can be used without an appreciable loss in 3D dose reconstruction accuracy for VMAT treatments. Methods: Six different VMAT plans and six different SBRT-VMAT plans were delivered to an anthropomorphic phantom. Delivery was carried out on a Varian 2300ix model linear accelerator (Linac) equipped with an aS1000 EPID running at a frame acquisition rate of 7.5 Hz. An additional PC was set up at the Linac console area, equipped with specialized frame-grabber hardware and software packages allowing continuous acquisition of all EPID frames during delivery. Frames were averaged into “frame-averaged” EPID images using MATLAB. Each frame-averaged data set was used to calculate the in vivo dose to the patient and then compared to the single EPID frame in vivo dose calculation (the single frame calculation represents the highest possible angular resolution per EPID image). A mean percentage dose difference of low dose (<20% prescription dose) and high dose regions (>80% prescription dose) was calculated for each frame averaged scenario for each plan. The authors defined their unacceptable loss of accuracy as no more than a ±1% mean dose difference in the high dose region. Optimal frame average numbers were then determined as a function of the Linac’s average gantry speed and the dose per fraction. Results: The authors found that 9 and 11 frame averages were suitable for all VMAT and SBRT-VMAT treatments, respectively. This resulted in no more than a 1% loss to any of the dose region’s mean percentage difference when compared to the single frame reconstruction. The optimized number was dependent on the treatment’s dose per fraction and was determined to be as high as 14 for 12 Gy/fraction (fx), 15 for 8 Gy/fx, 11 for 6 Gy/fx, and 9 for 2 Gy/fx. Conclusions: The authors have determined an optimal EPID frame averaging number for multiple VMAT-type treatments. These are given as a function of the dose per fraction and average gantry speed. These optimized values are now used in the authors’ clinical, 3D, in vivo patient dosimetry program. This provides a reduction in calculation time while maintaining the authors’ required level of accuracy in the dose reconstruction.« less
Near-infrared high-resolution real-time omnidirectional imaging platform for drone detection
NASA Astrophysics Data System (ADS)
Popovic, Vladan; Ott, Beat; Wellig, Peter; Leblebici, Yusuf
2016-10-01
Recent technological advancements in hardware systems have made higher quality cameras. State of the art panoramic systems use them to produce videos with a resolution of 9000 x 2400 pixels at a rate of 30 frames per second (fps).1 Many modern applications use object tracking to determine the speed and the path taken by each object moving through a scene. The detection requires detailed pixel analysis between two frames. In fields like surveillance systems or crowd analysis, this must be achieved in real time.2 In this paper, we focus on the system-level design of multi-camera sensor acquiring near-infrared (NIR) spectrum and its ability to detect mini-UAVs in a representative rural Swiss environment. The presented results show the UAV detection from the trial that we conducted during a field trial in August 2015.
Recent Advances in 3D Time-Resolved Contrast-Enhanced MR Angiography
Riederer, Stephen J.; Haider, Clifton R.; Borisch, Eric A.; Weavers, Paul T.; Young, Phillip M.
2015-01-01
Contrast-enhanced MR angiography (CE-MRA) was first introduced for clinical studies approximately 20 years ago. Early work provided 3 to 4 mm spatial resolution with acquisition times in the 30 sec range. Since that time there has been continuing effort to provide improved spatial resolution with reduced acquisition time, allowing high resolution three-dimensional (3D) time-resolved studies. The purpose of this work is to describe how this has been accomplished. Specific technical enablers have been: improved gradients allowing reduced repetition times, improved k-space sampling and reconstruction methods, parallel acquisition particularly in two directions, and improved and higher count receiver coil arrays. These have collectively made high resolution time-resolved studies readily available for many anatomic regions. Depending on the application, approximate 1 mm isotropic resolution is now possible with frame times of several seconds. Clinical applications of time-resolved CE-MRA are briefly reviewed. PMID:26032598
Hippo in Super Resolution from Super Panorama
1998-07-03
This view of the "Hippo," 25 meters to the west of the lander, was produced by combining the "Super Panorama" frames from the IMP camera. Super resolution was applied to help to address questions about the texture of this rock and what it might tell us about its mode of origin. The composite color frames that make up this anaglyph were produced for both the right and left eye of the IMP. These composites consist of more than 15 frames per eye (because multiple sequences covered the same area), taken with different color filters that were enlarged by 500% and then co-added using Adobe Photoshop to produce, in effect, a super-resolution panchromatic frame that is sharper than an individual frame would be. These panchromatic frames were then colorized with the red, green, and blue filtered images from the same sequence. The color balance was adjusted to approximate the true color of Mars. The anaglyph view was produced by combining the left with the right eye color composite frames by assigning the left eye composite view to the red color plane and the right eye composite view to the green and blue color planes (cyan), to produce a stereo anaglyph mosaic. This mosaic can be viewed in 3-D on your computer monitor or in color print form by wearing red-blue 3-D glasses. http://photojournal.jpl.nasa.gov/catalog/PIA01421
High-performance IR detector modules
NASA Astrophysics Data System (ADS)
Wendler, Joachim; Cabanski, Wolfgang; Rühlich, Ingo; Ziegler, Johann
2004-02-01
The 3rd generation of infrared (IR) detection modules is expected to provide higher video resolution, advanced functions like multi band or multi color capability, higher frame rates, and better thermal resolution. AIM has developed staring and linear high performance focal plane arrays (FPA) integrated into detector/dewar cooler assemblies (IDCA). Linear FPA"s support high resolution formats such as 1920 x 1152 (HDTV), 1280 x 960, or 1536 x 1152. Standard format for staring FPA"s is 640 x 512. In this configuration, QEIP devices sensitive in the 8 10 µm band as well as MCT devices sensitive in the 3.4 5.0 µm band are available. A 256 x 256 high speed detection module allows a full frame rate >800 Hz. Especially usability of long wavelength devices in high performance FLIR systems does not only depend on the classical electrooptical performance parameters such as NEDT, detectivity, and response homogeneity, but are mainly characterized by the stability of the correction coefficients used for image correction. The FPA"s are available in suited integrated detector/dewar cooler assemblies. The linear cooling engines are designed for maximum stability of the focal plane temperature, low operating temperatures down to 60K, high MTTF lifetimes of 6000h and above even under high ambient temperature conditions. The IDCA"s are equipped with AIM standard or custom specific command and control electronics (CCE) providing a well defined interface to the system electronics. Video output signals are provided as 14 bit digital data rates up to 80 MHz for the high speed devices.
Structure-from-motion for MAV image sequence analysis with photogrammetric applications
NASA Astrophysics Data System (ADS)
Schönberger, J. L.; Fraundorfer, F.; Frahm, J.-M.
2014-08-01
MAV systems have found increased attention in the photogrammetric community as an (autonomous) image acquisition platform for accurate 3D reconstruction. For an accurate reconstruction in feasible time, the acquired imagery requires specialized SfM software. Current systems typically use high-resolution sensors in pre-planned flight missions from far distance. We describe and evaluate a new SfM pipeline specifically designed for sequential, close-distance, and low-resolution imagery from mobile cameras with relatively high frame-rate and high overlap. Experiments demonstrate reduced computational complexity by leveraging the temporal consistency, comparable accuracy and point density with respect to state-of-the-art systems.
Shrestha, Suman; Karellas, Andrew; Shi, Linxi; Gounis, Matthew J.; Bellazzini, Ronaldo; Spandre, Gloria; Brez, Alessandro; Minuti, Massimo
2016-01-01
Purpose: High-resolution, photon-counting, energy-resolved detector with fast-framing capability can facilitate simultaneous acquisition of precontrast and postcontrast images for subtraction angiography without pixel registration artifacts and can facilitate high-resolution real-time imaging during image-guided interventions. Hence, this study was conducted to determine the spatial resolution characteristics of a hexagonal pixel array photon-counting cadmium telluride (CdTe) detector. Methods: A 650 μm thick CdTe Schottky photon-counting detector capable of concurrently acquiring up to two energy-windowed images was operated in a single energy-window mode to include photons of 10 keV or higher. The detector had hexagonal pixels with apothem of 30 μm resulting in pixel pitch of 60 and 51.96 μm along the two orthogonal directions. The detector was characterized at IEC-RQA5 spectral conditions. Linear response of the detector was determined over the air kerma rate relevant to image-guided interventional procedures ranging from 1.3 nGy/frame to 91.4 μGy/frame. Presampled modulation transfer was determined using a tungsten edge test device. The edge-spread function and the finely sampled line spread function accounted for hexagonal sampling, from which the presampled modulation transfer function (MTF) was determined. Since detectors with hexagonal pixels require resampling to square pixels for distortion-free display, the optimal square pixel size was determined by minimizing the root-mean-squared-error of the aperture functions for the square and hexagonal pixels up to the Nyquist limit. Results: At Nyquist frequencies of 8.33 and 9.62 cycles/mm along the apothem and orthogonal to the apothem directions, the modulation factors were 0.397 and 0.228, respectively. For the corresponding axis, the limiting resolution defined as 10% MTF occurred at 13.3 and 12 cycles/mm, respectively. Evaluation of the aperture functions yielded an optimal square pixel size of 54 μm. After resampling to 54 μm square pixels using trilinear interpolation, the presampled MTF at Nyquist frequency of 9.26 cycles/mm was 0.29 and 0.24 along the orthogonal directions and the limiting resolution (10% MTF) occurred at approximately 12 cycles/mm. Visual analysis of a bar pattern image showed the ability to resolve close to 12 line-pairs/mm and qualitative evaluation of a neurovascular nitinol-stent showed the ability to visualize its struts at clinically relevant conditions. Conclusions: Hexagonal pixel array photon-counting CdTe detector provides high spatial resolution in single-photon counting mode. After resampling to optimal square pixel size for distortion-free display, the spatial resolution is preserved. The dual-energy capabilities of the detector could allow for artifact-free subtraction angiography and basis material decomposition. The proposed high-resolution photon-counting detector with energy-resolving capability can be of importance for several image-guided interventional procedures as well as for pediatric applications. PMID:27147324
Vedantham, Srinivasan; Shrestha, Suman; Karellas, Andrew; Shi, Linxi; Gounis, Matthew J; Bellazzini, Ronaldo; Spandre, Gloria; Brez, Alessandro; Minuti, Massimo
2016-05-01
High-resolution, photon-counting, energy-resolved detector with fast-framing capability can facilitate simultaneous acquisition of precontrast and postcontrast images for subtraction angiography without pixel registration artifacts and can facilitate high-resolution real-time imaging during image-guided interventions. Hence, this study was conducted to determine the spatial resolution characteristics of a hexagonal pixel array photon-counting cadmium telluride (CdTe) detector. A 650 μm thick CdTe Schottky photon-counting detector capable of concurrently acquiring up to two energy-windowed images was operated in a single energy-window mode to include photons of 10 keV or higher. The detector had hexagonal pixels with apothem of 30 μm resulting in pixel pitch of 60 and 51.96 μm along the two orthogonal directions. The detector was characterized at IEC-RQA5 spectral conditions. Linear response of the detector was determined over the air kerma rate relevant to image-guided interventional procedures ranging from 1.3 nGy/frame to 91.4 μGy/frame. Presampled modulation transfer was determined using a tungsten edge test device. The edge-spread function and the finely sampled line spread function accounted for hexagonal sampling, from which the presampled modulation transfer function (MTF) was determined. Since detectors with hexagonal pixels require resampling to square pixels for distortion-free display, the optimal square pixel size was determined by minimizing the root-mean-squared-error of the aperture functions for the square and hexagonal pixels up to the Nyquist limit. At Nyquist frequencies of 8.33 and 9.62 cycles/mm along the apothem and orthogonal to the apothem directions, the modulation factors were 0.397 and 0.228, respectively. For the corresponding axis, the limiting resolution defined as 10% MTF occurred at 13.3 and 12 cycles/mm, respectively. Evaluation of the aperture functions yielded an optimal square pixel size of 54 μm. After resampling to 54 μm square pixels using trilinear interpolation, the presampled MTF at Nyquist frequency of 9.26 cycles/mm was 0.29 and 0.24 along the orthogonal directions and the limiting resolution (10% MTF) occurred at approximately 12 cycles/mm. Visual analysis of a bar pattern image showed the ability to resolve close to 12 line-pairs/mm and qualitative evaluation of a neurovascular nitinol-stent showed the ability to visualize its struts at clinically relevant conditions. Hexagonal pixel array photon-counting CdTe detector provides high spatial resolution in single-photon counting mode. After resampling to optimal square pixel size for distortion-free display, the spatial resolution is preserved. The dual-energy capabilities of the detector could allow for artifact-free subtraction angiography and basis material decomposition. The proposed high-resolution photon-counting detector with energy-resolving capability can be of importance for several image-guided interventional procedures as well as for pediatric applications.
Fast I/O for Massively Parallel Applications
NASA Technical Reports Server (NTRS)
OKeefe, Matthew T.
1996-01-01
The two primary goals for this report were the design, contruction and modeling of parallel disk arrays for scientific visualization and animation, and a study of the IO requirements of highly parallel applications. In addition, further work in parallel display systems required to project and animate the very high-resolution frames resulting from our supercomputing simulations in ocean circulation and compressible gas dynamics.
NASA Astrophysics Data System (ADS)
Blackford, Ethan B.; Estepp, Justin R.
2015-03-01
Non-contact, imaging photoplethysmography uses cameras to facilitate measurements including pulse rate, pulse rate variability, respiration rate, and blood perfusion by measuring characteristic changes in light absorption at the skin's surface resulting from changes in blood volume in the superficial microvasculature. Several factors may affect the accuracy of the physiological measurement including imager frame rate, resolution, compression, lighting conditions, image background, participant skin tone, and participant motion. Before this method can gain wider use outside basic research settings, its constraints and capabilities must be well understood. Recently, we presented a novel approach utilizing a synchronized, nine-camera, semicircular array backed by measurement of an electrocardiogram and fingertip reflectance photoplethysmogram. Twenty-five individuals participated in six, five-minute, controlled head motion artifact trials in front of a black and dynamic color backdrop. Increasing the input channel space for blind source separation using the camera array was effective in mitigating error from head motion artifact. Herein we present the effects of lower frame rates at 60 and 30 (reduced from 120) frames per second and reduced image resolution at 329x246 pixels (one-quarter of the original 658x492 pixel resolution) using bilinear and zero-order downsampling. This is the first time these factors have been examined for a multiple imager array and align well with previous findings utilizing a single imager. Examining windowed pulse rates, there is little observable difference in mean absolute error or error distributions resulting from reduced frame rates or image resolution, thus lowering requirements for systems measuring pulse rate over sufficient length time windows.
Rudin, Stephen; Kuhls, Andrew T.; Yadava, Girijesh K.; Josan, Gaurav C.; Wu, Ye; Chityala, Ravishankar N.; Rangwala, Hussain S.; Ciprian Ionita, N.; Hoffmann, Kenneth R.; Bednarek, Daniel R.
2011-01-01
New cone-beam computed tomographic (CBCT) mammography system designs are presented where the detectors provide high spatial resolution, high sensitivity, low noise, wide dynamic range, negligible lag and high frame rates similar to features required for high performance fluoroscopy detectors. The x-ray detectors consist of a phosphor coupled by a fiber-optic taper to either a high gain image light amplifier (LA) then CCD camera or to an electron multiplying CCD. When a square-array of such detectors is used, a field-of-view (FOV) to 20 × 20 cm can be obtained where the images have pixel-resolution of 100 µm or better. To achieve practical CBCT mammography scan-times, 30 fps may be acquired with quantum limited (noise free) performance below 0.2 µR detector exposure per frame. Because of the flexible voltage controlled gain of the LA’s and EMCCDs, large detector dynamic range is also achievable. Features of such detector systems with arrays of either generation 2 (Gen 2) or 3 (Gen 3) LAs optically coupled to CCD cameras or arrays of EMCCDs coupled directly are compared. Quantum accounting analysis is done for a variety of such designs where either the lowest number of information carriers off the LA photo-cathode or electrons released in the EMCCDs per x-ray absorbed in the phosphor are large enough to imply no quantum sink for the design. These new LA- or EMCCD-based systems could lead to vastly improved CBCT mammography, ROI-CT, or fluoroscopy performance compared to systems using flat panels. PMID:21297904
NASA Astrophysics Data System (ADS)
Rudin, Stephen; Kuhls, Andrew T.; Yadava, Girijesh K.; Josan, Gaurav C.; Wu, Ye; Chityala, Ravishankar N.; Rangwala, Hussain S.; Ionita, N. Ciprian; Hoffmann, Kenneth R.; Bednarek, Daniel R.
2006-03-01
New cone-beam computed tomographic (CBCT) mammography system designs are presented where the detectors provide high spatial resolution, high sensitivity, low noise, wide dynamic range, negligible lag and high frame rates similar to features required for high performance fluoroscopy detectors. The x-ray detectors consist of a phosphor coupled by a fiber-optic taper to either a high gain image light amplifier (LA) then CCD camera or to an electron multiplying CCD. When a square-array of such detectors is used, a field-of-view (FOV) to 20 x 20 cm can be obtained where the images have pixel-resolution of 100 μm or better. To achieve practical CBCT mammography scan-times, 30 fps may be acquired with quantum limited (noise free) performance below 0.2 μR detector exposure per frame. Because of the flexible voltage controlled gain of the LA's and EMCCDs, large detector dynamic range is also achievable. Features of such detector systems with arrays of either generation 2 (Gen 2) or 3 (Gen 3) LAs optically coupled to CCD cameras or arrays of EMCCDs coupled directly are compared. Quantum accounting analysis is done for a variety of such designs where either the lowest number of information carriers off the LA photo-cathode or electrons released in the EMCCDs per x-ray absorbed in the phosphor are large enough to imply no quantum sink for the design. These new LA- or EMCCD-based systems could lead to vastly improved CBCT mammography, ROI-CT, or fluoroscopy performance compared to systems using flat panels.
Informative frame detection from wireless capsule video endoscopic images
NASA Astrophysics Data System (ADS)
Bashar, Md. Khayrul; Mori, Kensaku; Suenaga, Yasuhito; Kitasaka, Takayuki; Mekada, Yoshito
2008-03-01
Wireless capsule endoscopy (WCE) is a new clinical technology permitting the visualization of the small bowel, the most difficult segment of the digestive tract. The major drawback of this technology is the high amount of time for video diagnosis. In this study, we propose a method for informative frame detection by isolating useless frames that are substantially covered by turbid fluids or their contamination with other materials, e.g., faecal, semi-processed or unabsorbed foods etc. Such materials and fluids present a wide range of colors, from brown to yellow, and/or bubble-like texture patterns. The detection scheme, therefore, consists of two stages: highly contaminated non-bubbled (HCN) frame detection and significantly bubbled (SB) frame detection. Local color moments in the Ohta color space are used to characterize HCN frames, which are isolated by the Support Vector Machine (SVM) classifier in Stage-1. The rest of the frames go to the Stage-2, where Laguerre gauss Circular Harmonic Functions (LG-CHFs) extract the characteristics of the bubble-structures in a multi-resolution framework. An automatic segmentation method is designed to extract the bubbled regions based on local absolute energies of the CHF responses, derived from the grayscale version of the original color image. Final detection of the informative frames is obtained by using threshold operation on the extracted regions. An experiment with 20,558 frames from the three videos shows the excellent average detection accuracy (96.75%) by the proposed method, when compared with the Gabor based- (74.29%) and discrete wavelet based features (62.21%).
An alternative resolution to the Mansuripur paradox
NASA Astrophysics Data System (ADS)
Redfern, Francis
2016-04-01
In 2013 an article published online by the journal Science declared that the paradox proposed by Masud Mansuripur was resolved. This paradox concerns a point charge-Amperian magnetic dipole system as seen in a frame of reference where they are at rest and one in which they are moving. In the latter frame an electric dipole appears on the magnetic dipole. A torque is then exerted upon the electric dipole by the point charge, a torque that is not observed in the at-rest frame. Mansuripur points out this violates the relativity principle and suggests the Lorentz force responsible for the torque be replaced by the Einstein-Laub force. The resolution of the paradox reported by Science, based on numerous papers in the physics literature, preserves the Lorentz force but depends on the concept of hidden momentum. Here I propose a different resolution based on the overlooked fact that the charge-magnetic dipole system contains linear and angular electromagnetic field momentum. The time rate of change of the field angular-momentum in the frame through which the system is moving cancels that due to the charge-electric dipole interaction. From this point of view hidden momentum is not needed in the resolution of the paradox.
Video framerate, resolution and grayscale tradeoffs for undersea telemanipulator
NASA Technical Reports Server (NTRS)
Ranadive, V.; Sheridan, T. B.
1981-01-01
The product of Frame Rate (F) in frames per second, Resolution (R) in total pixels and grayscale in bits (G) equals the transmission band rate in bits per second. Thus for a fixed channel capacity there are tradeoffs between F, R and G in the actual sampling of the picture for a particular manual control task in the present case remote undersea manipulation. A manipulator was used in the MASTER/SLAVE mode to study these tradeoffs. Images were systematically degraded from 28 frames per second, 128 x 128 pixels and 16 levels (4 bits) grayscale, with various FRG combinations constructed from a real-time digitized (charge-injection) video camera. It was found that frame rate, resolution and grayscale could be independently reduced without preventing the operator from accomplishing his/her task. Threshold points were found beyond which degradation would prevent any successful performance. A general conclusion is that a well trained operator can perform familiar remote manipulator tasks with a considerably degrade picture, down to 50 K bits/ sec.
A new sampling scheme for tropical forest monitoring using satellite imagery
Frederic Achard; Tim Richards; Javier Gallego
2000-01-01
At the global level, a sampling scheme for tropical forest change assessment, using high resolution satellite images, has been defined using sampling units independent of any particular satellite sensor. For this purpose, a sampling frame has been chosen a hexagonal tessellation of 3,600 km².
Next generation of pnCCDs for X-ray spectroscopy and imaging
NASA Astrophysics Data System (ADS)
Meidinger, Norbert; Andritschke, Robert; Hälker, Olaf; Hartmann, Robert; Herrmann, Sven; Holl, Peter; Lutz, Gerhard; Kimmel, Nils; Schaller, Gerhard; Schnecke, Martina; Schopper, Florian; Soltau, Heike; Strüder, Lothar
2006-11-01
A special type of charge-coupled device, the pnCCD, has been developed in the nineties as focal-plane detector for the X-ray astronomy mission XMM-Newton of the European Space Agency. The pnCCD detector has been in operation since the satellite launch in 1999. It is performing up to date spectroscopy of X-rays in combination with imaging and high time resolution. The excellent performance of the flight camera is still maintained; in particular, the energy resolution has been nearly constant since launch. In order to satisfy the requirements of future X-ray astronomy missions as well as those of ground-based experiments, a new type of pnCCD has been developed. The ‘frame store pnCCD’ shows various optimizations in device design and fabrication process. Devices with up to 256×512 pixels have been fabricated in 2004 and recently tested. Simultaneously, a programmable analog signal processor for the readout of the CCD signals, the DUO CAMEX, has been developed. The readout noise of the new detector has a value of 2 electrons ENC which is less than half of the figure of the XMM-Newton pnCCD. We measured an energy resolution that is close to the theoretical limit given by the Fano noise. In particular the low-energy response of the new devices was substantially improved. The quantum efficiency for X-rays is at least 90% in the entire energy band from 0.3 keV up to 11 keV. This is due to the ultra-thin photon entrance window as well as the full depletion of the 450 μm thick back-illuminated pnCCD. The position resolution is better than the pixel sizes of 75 μm×75 μm or 51 μm×51 μm because the signal charge is spread over up to four pixels which allows a more accurate event position determination. ‘Out of time’ events are substantially reduced to the order of 0.1% by operating the pnCCD in frame store mode. Higher operating temperatures, e.g. -20 °C, are possible due to the smaller thermally generated dark-current level of the new devices and the operation at higher frame rates. Low power consumption applications like for the ROSITA X-ray astronomy mission with low frame rates of, e.g. 20 images/s, as well as high frame rate applications, e.g. 200 images/s, are possible with the same device.
Imaging a seizure model in zebrafish with structured illumination light sheet microscopy
NASA Astrophysics Data System (ADS)
Liu, Yang; Dale, Savannah; Ball, Rebecca; VanLeuven, Ariel J.; Baraban, Scott; Sornborger, Andrew; Lauderdale, James D.; Kner, Peter
2018-02-01
Zebrafish are a promising vertebrate model for elucidating how neural circuits generate behavior under normal and pathological conditions. The Baraban group first demonstrated that zebrafish larvae are valuable for investigating seizure events and can be used as a model for epilepsy in humans. Because of their small size and transparency, zebrafish embryos are ideal for imaging seizure activity using calcium indicators. Light-sheet microscopy is well suited to capturing neural activity in zebrafish because it is capable of optical sectioning, high frame rates, and low excitation intensities. We describe work in our lab to use light-sheet microscopy for high-speed long-time imaging of neural activity in wildtype and mutant zebrafish to better understand the connectivity and activity of inhibitory neural networks when GABAergic signaling is altered in vivo. We show that, with light-sheet microscopy, neural activity can be recorded at 23 frames per second in twocolors for over 10 minutes allowing us to capture rare seizure events in mutants. We have further implemented structured illumination to increase resolution and contrast in the vertical and axial directions during high-speed imaging at an effective frame rate of over 7 frames per second.
Framing and the health policy process: a scoping review
Koon, Adam D; Hawkins, Benjamin; Mayhew, Susannah H
2016-01-01
Framing research seeks to understand the forces that shape human behaviour in the policy process. It assumes that policy is a social construct and can be cast in a variety of ways to imply multiple legitimate value considerations. Frames provide the cognitive means of making sense of the social world, but discordance among them forms the basis of policy contestation. Framing, as both theory and method, has proven to generate considerable insight into the nature of policy debates in a variety of disciplines. Despite its salience for understanding health policy debates; however, little is known about the ways frames influence the health policy process. A scoping review using the Arksey and O’Malley framework was conducted. The literature on framing in the health sector was reviewed using nine health and social science databases. Articles were included that explicitly reported theory and methods used, data source(s), at least one frame, frame sponsor and evidence of a given frame’s effect on the health policy process. A total of 52 articles, from 1996 to 2014, and representing 12 countries, were identified. Much of the research came from the policy studies/political science literature (n = 17) and used a constructivist epistemology. The term ‘frame’ was used as a label to describe a variety of ideas, packaged as values, social problems, metaphors or arguments. Frames were characterized at various levels of abstraction ranging from general ideological orientations to specific policy positions. Most articles presented multiple frames and showed how actors advocated for them in a highly contested political process. Framing is increasingly an important, yet overlooked aspect of the policy process. Further analysis on frames, framing processes and frame conflict can help researchers and policymakers to understand opaque and highly charged policy issues, which may facilitate the resolution of protracted policy controversies. PMID:26873903
Nanosurveyor: a framework for real-time data processing
Daurer, Benedikt J.; Krishnan, Hari; Perciano, Talita; ...
2017-01-31
Background: The ever improving brightness of accelerator based sources is enabling novel observations and discoveries with faster frame rates, larger fields of view, higher resolution, and higher dimensionality. Results: Here we present an integrated software/algorithmic framework designed to capitalize on high-throughput experiments through efficient kernels, load-balanced workflows, which are scalable in design. We describe the streamlined processing pipeline of ptychography data analysis. Conclusions: The pipeline provides throughput, compression, and resolution as well as rapid feedback to the microscope operators.
1979-07-10
Range : 1,550,000 km ( 961,000 miles ) These high resolution pictures of Jupiter's ring were obtained by Voyager 2 some 26 hrs. past the planet, 2 degrees below the ring plane. The forward scattering of sunlight reveals a radial distribution and density gradient of very small particles extending inward from the ring toward Jupiter. There is an indication of structure within the ring, but unfortunatly the spacecrafts motion during these long exposures blurred out the highest resolution detail, particularly in the frame at right.
Nagel, S R; Hilsabeck, T J; Bell, P M; Bradley, D K; Ayers, M J; Piston, K; Felker, B; Kilkenny, J D; Chung, T; Sammuli, B; Hares, J D; Dymoke-Bradshaw, A K L
2014-11-01
The DIlation X-ray Imager (DIXI) is a new, high-speed x-ray framing camera at the National Ignition Facility (NIF) sensitive to x-rays in the range of ≈2-17 keV. DIXI uses the pulse-dilation technique to achieve a temporal resolution of less than 10 ps, a ≈10× improvement over conventional framing cameras currently employed on the NIF (≈100 ps resolution), and otherwise only attainable with 1D streaked imaging. The pulse-dilation technique utilizes a voltage ramp to impart a velocity gradient on the signal-bearing electrons. The temporal response, spatial resolution, and x-ray sensitivity of DIXI are characterized with a short x-ray impulse generated using the COMET laser facility at Lawrence Livermore National Laboratory. At the NIF a pinhole array at 10 cm from target chamber center (tcc) projects images onto the photocathode situated outside the NIF chamber wall with a magnification of ≈64×. DIXI will provide important capabilities for warm-dense-matter physics, high-energy-density science, and inertial confinement fusion, adding important capabilities to temporally resolve hot-spot formation, x-ray emission, fuel motion, and mix levels in the hot-spot at neutron yields of up to 10(17). We present characterization data as well as first results on electron-transport phenomena in buried-layer foil experiments.
Adaptive Markov Random Fields for Example-Based Super-resolution of Faces
NASA Astrophysics Data System (ADS)
Stephenson, Todd A.; Chen, Tsuhan
2006-12-01
Image enhancement of low-resolution images can be done through methods such as interpolation, super-resolution using multiple video frames, and example-based super-resolution. Example-based super-resolution, in particular, is suited to images that have a strong prior (for those frameworks that work on only a single image, it is more like image restoration than traditional, multiframe super-resolution). For example, hallucination and Markov random field (MRF) methods use examples drawn from the same domain as the image being enhanced to determine what the missing high-frequency information is likely to be. We propose to use even stronger prior information by extending MRF-based super-resolution to use adaptive observation and transition functions, that is, to make these functions region-dependent. We show with face images how we can adapt the modeling for each image patch so as to improve the resolution.
NASA Astrophysics Data System (ADS)
Dore, A. J.; Kryza, M.; Hall, J. R.; Hallsworth, S.; Keller, V. J. D.; Vieno, M.; Sutton, M. A.
2011-12-01
The Fine Resolution Atmospheric Multi-pollutant Exchange model (FRAME) has been applied to model the spatial distribution of nitrogen deposition and air concentration over the UK at a 1 km spatial resolution. The modelled deposition and concentration data were gridded at resolutions of 1 km, 5 km and 50 km to test the sensitivity of calculations of the exceedance of critical loads for nitrogen deposition to the deposition data resolution. The modelled concentrations of NO2 were validated by comparison with measurements from the rural sites in the national monitoring network and were found to achieve better agreement with the high resolution 1 km data. High resolution plots were found to represent a more physically realistic distribution of nitrogen air concentrations and deposition resulting from use of 1 km resolution precipitation and emissions data as compared to 5 km resolution data. Summary statistics for national scale exceedance of the critical load for nitrogen deposition were not highly sensitive to the grid resolution of the deposition data but did show greater area exceedance with coarser grid resolution due to spatial averaging of high nitrogen deposition hot spots. Local scale deposition at individual Sites of Special Scientific Interest and high precipitation upland sites was sensitive to choice of grid resolution of deposition data. Use of high resolution data tended to generate lower deposition values in sink areas for nitrogen dry deposition (Sites of Scientific Interest) and higher values in high precipitation upland areas. In areas with generally low exceedance (Scotland) and for certain vegetation types (montane), the exceedance statistics were more sensitive to model data resolution.
NASA Astrophysics Data System (ADS)
Dore, A. J.; Kryza, M.; Hall, J. R.; Hallsworth, S.; Keller, V. J. D.; Vieno, M.; Sutton, M. A.
2012-05-01
The Fine Resolution Atmospheric Multi-pollutant Exchange model (FRAME) was applied to model the spatial distribution of reactive nitrogen deposition and air concentration over the United Kingdom at a 1 km spatial resolution. The modelled deposition and concentration data were gridded at resolutions of 1 km, 5 km and 50 km to test the sensitivity of calculations of the exceedance of critical loads for nitrogen deposition to the deposition data resolution. The modelled concentrations of NO2 were validated by comparison with measurements from the rural sites in the national monitoring network and were found to achieve better agreement with the high resolution 1 km data. High resolution plots were found to represent a more physically realistic distribution of reactive nitrogen air concentrations and deposition resulting from use of 1 km resolution precipitation and emissions data as compared to 5 km resolution data. Summary statistics for national scale exceedance of the critical load for nitrogen deposition were not highly sensitive to the grid resolution of the deposition data but did show greater area exceedance with coarser grid resolution due to spatial averaging of high nitrogen deposition hot spots. Local scale deposition at individual Sites of Special Scientific Interest and high precipitation upland sites was sensitive to choice of grid resolution of deposition data. Use of high resolution data tended to generate lower deposition values in sink areas for nitrogen dry deposition (Sites of Scientific Interest) and higher values in high precipitation upland areas. In areas with generally low exceedance (Scotland) and for certain vegetation types (montane), the exceedance statistics were more sensitive to model data resolution.
Robust image alignment for cryogenic transmission electron microscopy.
McLeod, Robert A; Kowal, Julia; Ringler, Philippe; Stahlberg, Henning
2017-03-01
Cryo-electron microscopy recently experienced great improvements in structure resolution due to direct electron detectors with improved contrast and fast read-out leading to single electron counting. High frames rates enabled dose fractionation, where a long exposure is broken into a movie, permitting specimen drift to be registered and corrected. The typical approach for image registration, with high shot noise and low contrast, is multi-reference (MR) cross-correlation. Here we present the software package Zorro, which provides robust drift correction for dose fractionation by use of an intensity-normalized cross-correlation and logistic noise model to weight each cross-correlation in the MR model and filter each cross-correlation optimally. Frames are reliably registered by Zorro with low dose and defocus. Methods to evaluate performance are presented, by use of independently-evaluated even- and odd-frame stacks by trajectory comparison and Fourier ring correlation. Alignment of tiled sub-frames is also introduced, and demonstrated on an example dataset. Zorro source code is available at github.com/CINA/zorro. Copyright © 2016 Elsevier Inc. All rights reserved.
Kim, Daehyeok; Song, Minkyu; Choe, Byeongseong; Kim, Soo Youn
2017-06-25
In this paper, we present a multi-resolution mode CMOS image sensor (CIS) for intelligent surveillance system (ISS) applications. A low column fixed-pattern noise (CFPN) comparator is proposed in 8-bit two-step single-slope analog-to-digital converter (TSSS ADC) for the CIS that supports normal, 1/2, 1/4, 1/8, 1/16, 1/32, and 1/64 mode of pixel resolution. We show that the scaled-resolution images enable CIS to reduce total power consumption while images hold steady without events. A prototype sensor of 176 × 144 pixels has been fabricated with a 0.18 μm 1-poly 4-metal CMOS process. The area of 4-shared 4T-active pixel sensor (APS) is 4.4 μm × 4.4 μm and the total chip size is 2.35 mm × 2.35 mm. The maximum power consumption is 10 mW (with full resolution) with supply voltages of 3.3 V (analog) and 1.8 V (digital) and 14 frame/s of frame rates.
[Improvement of Digital Capsule Endoscopy System and Image Interpolation].
Zhao, Shaopeng; Yan, Guozheng; Liu, Gang; Kuang, Shuai
2016-01-01
Traditional capsule image collects and transmits analog image, with weak anti-interference ability, low frame rate, low resolution. This paper presents a new digital image capsule, which collects and transmits digital image, with frame rate up to 30 frames/sec and pixels resolution of 400 x 400. The image is compressed in the capsule, and is transmitted to the outside of the capsule for decompression and interpolation. A new type of interpolation algorithm is proposed, which is based on the relationship between the image planes, to obtain higher quality colour images. capsule endoscopy, digital image, SCCB protocol, image interpolation
Integrated sensor with frame memory and programmable resolution for light adaptive imaging
NASA Technical Reports Server (NTRS)
Zhou, Zhimin (Inventor); Fossum, Eric R. (Inventor); Pain, Bedabrata (Inventor)
2004-01-01
An image sensor operable to vary the output spatial resolution according to a received light level while maintaining a desired signal-to-noise ratio. Signals from neighboring pixels in a pixel patch with an adjustable size are added to increase both the image brightness and signal-to-noise ratio. One embodiment comprises a sensor array for receiving input signals, a frame memory array for temporarily storing a full frame, and an array of self-calibration column integrators for uniform column-parallel signal summation. The column integrators are capable of substantially canceling fixed pattern noise.
High-resolution panoramic images with megapixel MWIR FPA
NASA Astrophysics Data System (ADS)
Leboucher, Vincent; Aubry, Gilles
2014-06-01
In the continuity of its current strategy, HGH maintains a deep effort in developing its most recent product family: the infrared (IR) panoramic 360-degree surveillance sensors. During the last two years, HGH optimized its prototype Middle Wave IR (MWIR) panoramic sensor IR Revolution 360 HD that gave birth to Spynel-S product. Various test campaigns proved its excellent image quality. Cyclope, the software associated with Spynel, benefitted from recent image processing improvements and new functionalities such as target geolocalization, long range sensor slue to cue and facilitated forensics analysis. In the frame of the PANORAMIR project sustained by the DGA (Délégation Générale de l'Armement), HGH designed a new extra large resolution sensor including a MWIR megapixel Focal Plane Array (FPA) detector (1280×1024 pixels). This new sensor is called Spynel-X. It provides outstanding resolution 360-degree images (with more than 100 Mpixels). The mechanical frame of Spynel (-S and -X) was designed with the collaboration of an industrial design agency. Spynel got the "Observeur du Design 2013" label.
Image analysis for microelectronic retinal prosthesis.
Hallum, L E; Cloherty, S L; Lovell, N H
2008-01-01
By way of extracellular, stimulating electrodes, a microelectronic retinal prosthesis aims to render discrete, luminous spots-so-called phosphenes-in the visual field, thereby providing a phosphene image (PI) as a rudimentary remediation of profound blindness. As part thereof, a digital camera, or some other photosensitive array, captures frames, frames are analyzed, and phosphenes are actuated accordingly by way of modulated charge injections. Here, we present a method that allows the assessment of image analysis schemes for integration with a prosthetic device, that is, the means of converting the captured image (high resolution) to modulated charge injections (low resolution). We use the mutual-information function to quantify the amount of information conveyed to the PI observer (device implantee), while accounting for the statistics of visual stimuli. We demonstrate an effective scheme involving overlapping, Gaussian kernels, and discuss extensions of the method to account for shortterm visual memory in observers, and their perceptual errors of omission and commission.
NASA Astrophysics Data System (ADS)
Hariri, Ali; Bely, Nicholas; Chen, Chen; Nasiriavanaki, Mohammadreza
2016-03-01
The increasing use of mouse models for human brain disease studies, coupled with the fact that existing high-resolution functional imaging modalities cannot be easily applied to mice, presents an emerging need for a new functional imaging modality. Utilizing both mechanical and optical scanning in the photoacoustic microscopy, we can image spontaneous cerebral hemodynamic fluctuations and their associated functional connections in the mouse brain. The images is going to be acquired noninvasively with a fast frame rate, a large field of view, and a high spatial resolution. We developed an optical resolution photoacoustic microscopy (OR-PAM) with diode laser. Laser light was raster scanned due to XY-stage movement. Images from ultra-high OR-PAM can then be used to study brain disorders such as stroke, Alzheimer's, schizophrenia, multiple sclerosis, autism, and epilepsy.
Furukawa, Taichi; Kanamori, Satoshi; Fukuta, Masahiro; Nawa, Yasunori; Kominami, Hiroko; Nakanishi, Yoichiro; Sugita, Atsushi; Inami, Wataru; Kawata, Yoshimasa
2015-07-13
We fabricated a bright and thin Zn₂SiO₄ luminescent film to serve as a nanometric light source for high-spatial-resolution optical microscopy based on electron beam excitation. The Zn₂SiO₄ luminescent thin film was fabricated by annealing a ZnO film on a Si₃N₄ substrate at 1000 °C in N₂. The annealed film emitted bright cathodoluminescence compared with the as-deposited film. The film is promising for nano-imaging with electron beam excitation-assisted optical microscopy. We evaluated the spatial resolution of a microscope developed using this Zn₂SiO₄ luminescent thin film. This is the first report of the investigation and application of ZnO/Si₃N₄ annealed at a high temperature (1000 °C). The fabricated Zn₂SiO₄ film is expected to enable high-frame-rate dynamic observation with ultra-high resolution using our electron beam excitation-assisted optical microscopy.
High-resolution depth profiling using a range-gated CMOS SPAD quanta image sensor.
Ren, Ximing; Connolly, Peter W R; Halimi, Abderrahim; Altmann, Yoann; McLaughlin, Stephen; Gyongy, Istvan; Henderson, Robert K; Buller, Gerald S
2018-03-05
A CMOS single-photon avalanche diode (SPAD) quanta image sensor is used to reconstruct depth and intensity profiles when operating in a range-gated mode used in conjunction with pulsed laser illumination. By designing the CMOS SPAD array to acquire photons within a pre-determined temporal gate, the need for timing circuitry was avoided and it was therefore possible to have an enhanced fill factor (61% in this case) and a frame rate (100,000 frames per second) that is more difficult to achieve in a SPAD array which uses time-correlated single-photon counting. When coupled with appropriate image reconstruction algorithms, millimeter resolution depth profiles were achieved by iterating through a sequence of temporal delay steps in synchronization with laser illumination pulses. For photon data with high signal-to-noise ratios, depth images with millimeter scale depth uncertainty can be estimated using a standard cross-correlation approach. To enhance the estimation of depth and intensity images in the sparse photon regime, we used a bespoke clustering-based image restoration strategy, taking into account the binomial statistics of the photon data and non-local spatial correlations within the scene. For sparse photon data with total exposure times of 75 ms or less, the bespoke algorithm can reconstruct depth images with millimeter scale depth uncertainty at a stand-off distance of approximately 2 meters. We demonstrate a new approach to single-photon depth and intensity profiling using different target scenes, taking full advantage of the high fill-factor, high frame rate and large array format of this range-gated CMOS SPAD array.
NASA Astrophysics Data System (ADS)
Lin, Shengtao; Zhang, Ge; Jamburidze, Akaki; Chee, Melisse; Hau Leow, Chee; Garbin, Valeria; Tang, Meng-Xing
2018-03-01
Phase-change ultrasound contrast agent (PCCA), or nanodroplet, shows promise as an alternative to the conventional microbubble agent over a wide range of diagnostic applications. Meanwhile, high-frame-rate (HFR) ultrasound imaging with microbubbles enables unprecedented temporal resolution compared to traditional contrast-enhanced ultrasound imaging. The combination of HFR ultrasound imaging and PCCAs can offer the opportunity to observe and better understand PCCA behaviour after vaporisation captures the fast phenomenon at a high temporal resolution. In this study, we utilised HFR ultrasound at frame rates in the kilohertz range (5-20 kHz) to image native and size-selected PCCA populations immediately after vaporisation in vitro within clinical acoustic parameters. The size-selected PCCAs through filtration are shown to preserve a sub-micron-sized (mean diameter < 200 nm) population without micron-sized outliers (>1 µm) that originate from native PCCA emulsion. The results demonstrate imaging signals with different amplitudes and temporal features compared to that of microbubbles. Compared with the microbubbles, both the B-mode and pulse-inversion (PI) signals from the vaporised PCCA populations were reduced significantly in the first tens of milliseconds, while only the B-mode signals from the PCCAs were recovered during the next 400 ms, suggesting significant changes to the size distribution of the PCCAs after vaporisation. It is also shown that such recovery in signal over time is not evident when using size-selective PCCAs. Furthermore, it was found that signals from the vaporised PCCA populations are affected by the amplitude and frame rate of the HFR ultrasound imaging. Using high-speed optical camera observation (30 kHz), we observed a change in particle size in the vaporised PCCA populations exposed to the HFR ultrasound imaging pulses. These findings can further the understanding of PCCA behaviour under HFR ultrasound imaging.
NASA Astrophysics Data System (ADS)
Gullberg, B.; Swinbank, A. M.; Smail, I.; Biggs, A. D.; Bertoldi, F.; De Breuck, C.; Chapman, S. C.; Chen, C.-C.; Cooke, E. A.; Coppin, K. E. K.; Cox, P.; Dannerbauer, H.; Dunlop, J. S.; Edge, A. C.; Farrah, D.; Geach, J. E.; Greve, T. R.; Hodge, J.; Ibar, E.; Ivison, R. J.; Karim, A.; Schinnerer, E.; Scott, D.; Simpson, J. M.; Stach, S. M.; Thomson, A. P.; van der Werf, P.; Walter, F.; Wardlow, J. L.; Weiss, A.
2018-05-01
We present deep, high-resolution (0.″03, 200 pc) ALMA Band 7 observations covering the dust continuum and [C II] λ157.7 μm emission in four z ∼ 4.4–4.8 sub-millimeter galaxies (SMGs) selected from the ALESS and AS2UDS surveys. The data show that the rest-frame 160 μm (observed 345 GHz) dust emission is consistent with smooth morphologies on kpc scales for three of the sources. One source, UDS 47.0, displays apparent substructure, but this is also consistent with a smooth morphology—as indicated by simulations showing that smooth exponential disks can appear clumpy when observed at the high angular resolution (0.″03) and depth of these observations ({σ }345{GHz}∼ 27{--}47 μJy beam‑1). The four SMGs are bright [C II] emitters. We extract [C II] spectra from the high-resolution data, and recover ∼20%–100% of the [C II] flux and ∼40%–80% of the dust continuum emission, compared to the previous lower-resolution observations. When tapered to 0.″2 resolution, our maps recover ∼80%–100% of the continuum emission, indicating that ∼60% of the emission is resolved out on ∼200 pc scales. We find that the [C II] emission in high-redshift galaxies is more spatially extended than the rest-frame 160 μm dust continuum by a factor of 1.6 ± 0.4. By considering the {L}[{{C}{{II}}]}/{L}FIR} ratio as a function of the star formation rate surface density ({{{Σ }}}SFR}), we revisit the [C II] deficit and suggest that the decline in the {L}[{{C}{{II}}]}/{L}FIR} ratio as a function of {{{Σ }}}SFR} is consistent with local processes. We also explore the physical drivers that may be responsible for these trends and can give rise to the properties found in the densest regions of SMGs.
Effect of subaperture beamforming on phase coherence imaging.
Hasegawa, Hideyuki; Kanai, Hiroshi
2014-11-01
High-frame-rate echocardiography using unfocused transmit beams and parallel receive beamforming is a promising method for evaluation of cardiac function, such as imaging of rapid propagation of vibration of the heart wall resulting from electrical stimulation of the myocardium. In this technique, high temporal resolution is realized at the expense of spatial resolution and contrast. The phase coherence factor has been developed to improve spatial resolution and contrast in ultrasonography. It evaluates the variance in phases of echo signals received by individual transducer elements after delay compensation, as in the conventional delay-andsum beamforming process. However, the phase coherence factor suppresses speckle echoes because phases of speckle echoes fluctuate as a result of interference of echoes. In the present study, the receiving aperture was divided into several subapertures, and conventional delay-and-sum beamforming was performed with respect to each subaperture to suppress echoes from scatterers except for that at a focal point. After subaperture beamforming, the phase coherence factor was obtained from beamformed RF signals from respective subapertures. By means of this procedure, undesirable echoes, which can interfere with the echo from a focal point, can be suppressed by subaperture beamforming, and the suppression of the phase coherence factor resulting from phase fluctuation caused by such interference can be avoided. In the present study, the effect of subaperture beamforming in high-frame-rate echocardiography with the phase coherence factor was evaluated using a phantom. By applying subaperture beamforming, the average intensity of speckle echoes from a diffuse scattering medium was significantly higher (-39.9 dB) than that obtained without subaperture beamforming (-48.7 dB). As for spatial resolution, the width at half-maximum of the lateral echo amplitude profile obtained without the phase coherence factor was 1.06 mm. By using the phase coherence factor, spatial resolution was improved significantly, and subaperture beamforming achieved a better spatial resolution of 0.75 mm than that of 0.78 mm obtained without subaperture beamforming.
NASA Astrophysics Data System (ADS)
Raphael, David T.; McIntee, Diane; Tsuruda, Jay S.; Colletti, Patrick; Tatevossian, Raymond; Frazier, James
2006-03-01
We explored multiple image processing approaches by which to display the segmented adult brachial plexus in a three-dimensional manner. Magnetic resonance neurography (MRN) 1.5-Tesla scans with STIR sequences, which preferentially highlight nerves, were performed in adult volunteers to generate high-resolution raw images. Using multiple software programs, the raw MRN images were then manipulated so as to achieve segmentation of plexus neurovascular structures, which were incorporated into three different visualization schemes: rotating upper thoracic girdle skeletal frames, dynamic fly-throughs parallel to the clavicle, and thin slab volume-rendered composite projections.
Development and Evaluation of a Dynamic, 3-Degree-of-Freedom (DOF) Wind Tunnel Model
2016-11-01
DATE (DD-MM-YYYY) November 2016 2. REPORT TYPE Contractor Report 3. DATES COVERED (From - To) November 2014–October 2015 4. TITLE AND SUBTITLE...eliminates any gimbal-induced flow disturbances. All 3 axes can be locked independently and are instrumented with high -resolution feedback. Experiments... high -speed video frames of the subsonic model in the transonic wind tunnel, Run 63
X-ray imaging detectors for synchrotron and XFEL sources
Hatsui, Takaki; Graafsma, Heinz
2015-01-01
Current trends for X-ray imaging detectors based on hybrid and monolithic detector technologies are reviewed. Hybrid detectors with photon-counting pixels have proven to be very powerful tools at synchrotrons. Recent developments continue to improve their performance, especially for higher spatial resolution at higher count rates with higher frame rates. Recent developments for X-ray free-electron laser (XFEL) experiments provide high-frame-rate integrating detectors with both high sensitivity and high peak signal. Similar performance improvements are sought in monolithic detectors. The monolithic approach also offers a lower noise floor, which is required for the detection of soft X-ray photons. The link between technology development and detector performance is described briefly in the context of potential future capabilities for X-ray imaging detectors. PMID:25995846
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vedantham, Srinivasan; Shrestha, Suman; Karellas, Andrew, E-mail: andrew.karellas@umassmed.edu
Purpose: High-resolution, photon-counting, energy-resolved detector with fast-framing capability can facilitate simultaneous acquisition of precontrast and postcontrast images for subtraction angiography without pixel registration artifacts and can facilitate high-resolution real-time imaging during image-guided interventions. Hence, this study was conducted to determine the spatial resolution characteristics of a hexagonal pixel array photon-counting cadmium telluride (CdTe) detector. Methods: A 650 μm thick CdTe Schottky photon-counting detector capable of concurrently acquiring up to two energy-windowed images was operated in a single energy-window mode to include photons of 10 keV or higher. The detector had hexagonal pixels with apothem of 30 μm resulting in pixelmore » pitch of 60 and 51.96 μm along the two orthogonal directions. The detector was characterized at IEC-RQA5 spectral conditions. Linear response of the detector was determined over the air kerma rate relevant to image-guided interventional procedures ranging from 1.3 nGy/frame to 91.4 μGy/frame. Presampled modulation transfer was determined using a tungsten edge test device. The edge-spread function and the finely sampled line spread function accounted for hexagonal sampling, from which the presampled modulation transfer function (MTF) was determined. Since detectors with hexagonal pixels require resampling to square pixels for distortion-free display, the optimal square pixel size was determined by minimizing the root-mean-squared-error of the aperture functions for the square and hexagonal pixels up to the Nyquist limit. Results: At Nyquist frequencies of 8.33 and 9.62 cycles/mm along the apothem and orthogonal to the apothem directions, the modulation factors were 0.397 and 0.228, respectively. For the corresponding axis, the limiting resolution defined as 10% MTF occurred at 13.3 and 12 cycles/mm, respectively. Evaluation of the aperture functions yielded an optimal square pixel size of 54 μm. After resampling to 54 μm square pixels using trilinear interpolation, the presampled MTF at Nyquist frequency of 9.26 cycles/mm was 0.29 and 0.24 along the orthogonal directions and the limiting resolution (10% MTF) occurred at approximately 12 cycles/mm. Visual analysis of a bar pattern image showed the ability to resolve close to 12 line-pairs/mm and qualitative evaluation of a neurovascular nitinol-stent showed the ability to visualize its struts at clinically relevant conditions. Conclusions: Hexagonal pixel array photon-counting CdTe detector provides high spatial resolution in single-photon counting mode. After resampling to optimal square pixel size for distortion-free display, the spatial resolution is preserved. The dual-energy capabilities of the detector could allow for artifact-free subtraction angiography and basis material decomposition. The proposed high-resolution photon-counting detector with energy-resolving capability can be of importance for several image-guided interventional procedures as well as for pediatric applications.« less
Optical Diagnostic System For Observation Of Laser-Produced Shock Waves
NASA Astrophysics Data System (ADS)
Wilke, Mark D.; Stone, Sidney N.
1980-11-01
Several standard plasma and gas dynamic diagnostic techniques have been integrated into a system for observing the formation and propagation of high-power Nd:glass-laser generated one- and two-dimensional shockwaves in air from 0.1 torr to atmospheric pres-sures. Diagnostics include either single-frame, two-wavelength holographic ruby-laser interferometry or single-frame, single-wavelength interferometry with ten frames of shadow-graphy. Streaks or ten frames of the early luminous shocked region also are taken on all shots, as well as time-resolved luminosity measurements using high-speed biplanar vacuum photodiodes with various wavelength interference filters. Shadowgraphy frames are 200-ns long at 1-μs intervals, while emission frames are variable with a maximum 10-ns exposure and 50-ns interval. Both the streak mode and emission measurements with the vacuum diode allow subnanosecond time resolution. The interferometry provides 20-ns exposures from 500 ns to late times. Methods for reducing and interpreting the data have been, or are currently being, developed. Interactive computer programs for digitizing the fringe patterns provide fringe-shift profiles for Abel inversion. This has provided neutral gas and electron density information in the spherical, one-dimensional cases. Diagrams and photographs of the experiment will be shown as well as examples of the data that have been taken. Methods for data reduction will be outlined and some of the results shown.
Improved Resolution Optical Time Stretch Imaging Based on High Efficiency In-Fiber Diffraction.
Wang, Guoqing; Yan, Zhijun; Yang, Lei; Zhang, Lin; Wang, Chao
2018-01-12
Most overlooked challenges in ultrafast optical time stretch imaging (OTSI) are sacrificed spatial resolution and higher optical loss. These challenges are originated from optical diffraction devices used in OTSI, which encode image into spectra of ultrashort optical pulses. Conventional free-space diffraction gratings, as widely used in existing OTSI systems, suffer from several inherent drawbacks: limited diffraction efficiency in a non-Littrow configuration due to inherent zeroth-order reflection, high coupling loss between free-space gratings and optical fibers, bulky footprint, and more importantly, sacrificed imaging resolution due to non-full-aperture illumination for individual wavelengths. Here we report resolution-improved and diffraction-efficient OTSI using in-fiber diffraction for the first time to our knowledge. The key to overcome the existing challenges is a 45° tilted fiber grating (TFG), which serves as a compact in-fiber diffraction device offering improved diffraction efficiency (up to 97%), inherent compatibility with optical fibers, and improved imaging resolution owning to almost full-aperture illumination for all illumination wavelengths. 50 million frames per second imaging of fast moving object at 46 m/s with improved imaging resolution has been demonstrated. This conceptually new in-fiber diffraction design opens the way towards cost-effective, compact and high-resolution OTSI systems for image-based high-throughput detection and measurement.
Evaluation of Skybox Video and Still Image products
NASA Astrophysics Data System (ADS)
d'Angelo, P.; Kuschk, G.; Reinartz, P.
2014-11-01
The SkySat-1 satellite lauched by Skybox Imaging on November 21 in 2013 opens a new chapter in civilian earth observation as it is the first civilian satellite to image a target in high definition panchromatic video for up to 90 seconds. The small satellite with a mass of 100 kg carries a telescope with 3 frame sensors. Two products are available: Panchromatic video with a resolution of around 1 meter and a frame size of 2560 × 1080 pixels at 30 frames per second. Additionally, the satellite can collect still imagery with a swath of 8 km in the panchromatic band, and multispectral images with 4 bands. Using super-resolution techniques, sub-meter accuracy is reached for the still imagery. The paper provides an overview of the satellite design and imaging products. The still imagery product consists of 3 stripes of frame images with a footprint of approximately 2.6 × 1.1 km. Using bundle block adjustment, the frames are registered, and their accuracy is evaluated. Image quality of the panchromatic, multispectral and pansharpened products are evaluated. The video product used in this evaluation consists of a 60 second gazing acquisition of Las Vegas. A DSM is generated by dense stereo matching. Multiple techniques such as pairwise matching or multi image matching are used and compared. As no ground truth height reference model is availble to the authors, comparisons on flat surface and compare differently matched DSMs are performed. Additionally, visual inspection of DSM and DSM profiles show a detailed reconstruction of small features and large skyscrapers.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fedrigo, Anna, E-mail: anna.fedrigo@nbi.ku.dk; Istituto dei Sistemi Complessi, Consiglio Nazionale delle Ricerche, 50019 Sesto Fiorentino; European Spallation Source ESS AB, SE-221 00 Lund
VESPA, Vibrational Excitation Spectrometer with Pyrolytic-graphite Analysers, aims to probe molecular excitations via inelastic neutron scattering. It is a thermal high resolution inverted geometry time-of-flight instrument designed to maximise the use of the long pulse of the European Spallation Source. The wavelength frame multiplication technique was applied to provide simultaneously a broad dynamic range (about 0-500 meV) while a system of optical blind choppers allows to trade flux for energy resolution. Thanks to its high flux, VESPA will allow the investigation of dynamical and in situ experiments in physical chemistry. Here we describe the design parameters and the corresponding McStasmore » simulations.« less
Amor, Rumelo; McDonald, Alison; Trägårdh, Johanna; Robb, Gillian; Wilson, Louise; Abdul Rahman, Nor Zaihana; Dempster, John; Amos, William Bradshaw; Bushell, Trevor J.; McConnell, Gail
2016-01-01
We demonstrate fluorescence imaging by two-photon excitation without scanning in biological specimens as previously described by Hwang and co-workers, but with an increased field size and with framing rates of up to 100 Hz. During recordings of synaptically-driven Ca2+ events in primary rat hippocampal neurone cultures loaded with the fluorescent Ca2+ indicator Fluo-4 AM, we have observed greatly reduced photo-bleaching in comparison with single-photon excitation. This method, which requires no costly additions to the microscope, promises to be useful for work where high time-resolution is required. PMID:26824845
Gudur, Madhu Sudhan Reddy; Kumon, Ronald E; Zhou, Yun; Deng, Cheri X
2012-08-01
The goal of this study was to examine the ability of high-frame-rate, high-resolution imaging to monitor tissue necrosis and gas-body activities formed during high-intensity focused ultrasound (HIFU) application. Ex vivo porcine cardiac tissue specimens (n = 24) were treated with HIFU exposure (4.33 MHz, 77 to 130 Hz pulse repetition frequency (PRF), 25 to 50% duty cycle, 0.2 to 1 s, 2600 W/cm(2)). RF data from B-mode ultrasound imaging were obtained before, during, and after HIFU exposure at a frame rate ranging from 77 to 130 Hz using an ultrasound imaging system with a center frequency of 55 MHz. The time history of changes in the integrated backscatter (IBS), calibrated spectral parameters, and echo-decorrelation parameters of the RF data were assessed for lesion identification by comparison against gross sections. Temporal maximum IBS with +12 dB threshold achieved the best identification with a receiver-operating characteristic (ROC) curve area of 0.96. Frame-to-frame echo decorrelation identified and tracked transient gas-body activities. Macroscopic (millimeter-sized) cavities formed when the estimated initial expansion rate of gas bodies (rate of expansion in lateral-to-beam direction) crossed 0.8 mm/s. Together, these assessments provide a method for monitoring spatiotemporal evolution of lesion and gas-body activity and for predicting macroscopic cavity formation.
Combat vehicle crew helmet-mounted display: next generation high-resolution head-mounted display
NASA Astrophysics Data System (ADS)
Nelson, Scott A.
1994-06-01
The Combat Vehicle Crew Head-Mounted Display (CVC HMD) program is an ARPA-funded, US Army Natick Research, Development, and Engineering Center monitored effort to develop a high resolution, flat panel HMD for the M1 A2 Abrams main battle tank. CVC HMD is part of the ARPA High Definition Systems (HDS) thrust to develop and integrate small (24 micrometers square pels), high resolution (1280 X 1024 X 6-bit grey scale at 60 frame/sec) active matrix electroluminescent (AMEL) and active matrix liquid crystal displays (AMLCD) for head mounted and projection applications. The Honeywell designed CVC HMD is a next generation head-mounted display system that includes advanced flat panel image sources, advanced digital display driver electronics, high speed (> 1 Gbps) digital interconnect electronics, and light weight, high performance optical and mechanical designs. The resulting dramatic improvements in size, weight, power, and cost have already led to program spin offs for both military and commercial applications.
Surface coil proton MR imaging at 2 T.
Röschmann, P; Tischler, R
1986-10-01
We describe the design and application of surface coils for magnetic resonance (MR) imaging at high resonance frequencies (85 MHz). Circular, rectangular-frame, and reflector-type surface coils were used in the transmit-and-receive mode. With these coils, the required radio frequency power is reduced by factors of two up to 100 with respect to head and body coils. With the small, circular coils, high-resolution images of a small region of interest can be obtained that are free of foldback and motion artifacts originating outside the field of interest. With the rectangular-frame and reflector coils, large fields of view are also accessible. As examples of applications, single- and multiple-section images of the eye, knee, head and shoulder, and spinal cord are provided.
High speed line-scan confocal imaging of stimulus-evoked intrinsic optical signals in the retina
Li, Yang-Guo; Liu, Lei; Amthor, Franklin; Yao, Xin-Cheng
2010-01-01
A rapid line-scan confocal imager was developed for functional imaging of the retina. In this imager, an acousto-optic deflector (AOD) was employed to produce mechanical vibration- and inertia-free light scanning, and a high-speed (68,000 Hz) linear CCD camera was used to achieve sub-cellular and sub-millisecond spatiotemporal resolution imaging. Two imaging modalities, i.e., frame-by-frame and line-by-line recording, were validated for reflected light detection of intrinsic optical signals (IOSs) in visible light stimulus activated frog retinas. Experimental results indicated that fast IOSs were tightly correlated with retinal stimuli, and could track visible light flicker stimulus frequency up to at least 2 Hz. PMID:20125743
Novel eye-safe line scanning 3D laser-radar
NASA Astrophysics Data System (ADS)
Eberle, B.; Kern, Tobias; Hammer, Marcus; Schwanke, Ullrich; Nowak, Heinrich
2014-10-01
Today, the civil market provides quite a number of different 3D-Sensors covering ranges up to 1 km. Typically these sensors are based on single element detectors which suffer from the drawback of spatial resolution at larger distances. Tasks demanding reliable object classification at long ranges can be fulfilled only by sensors consisting of detector arrays. They ensure sufficient frame rates and high spatial resolution. Worldwide there are many efforts in developing 3D-detectors, based on two-dimensional arrays. This paper presents first results on the performance of a recently developed 3D imaging laser radar sensor, working in the short wave infrared (SWIR) at 1.5 μm. It consists of a novel Cadmium Mercury Telluride (CMT) linear array APD detector with 384x1 elements at a pitch of 25 μm, developed by AIM Infrarot Module GmbH. The APD elements are designed to work in the linear (non-Geiger) mode. Each pixel will provide the time of flight measurement, and, due to the linear detection mode, allowing the detection of three successive echoes. The resolution in depth is 15 cm, the maximum repetition rate is 4 kHz. We discuss various sensor concepts regarding possible applications and their dependence on system parameters like field of view, frame rate, spatial resolution and range of operation.
Massie, Norbert A.; Oster, Yale
1992-01-01
A large effective-aperture, low-cost optical telescope with diffraction-limited resolution enables ground-based observation of near-earth space objects. The telescope has a non-redundant, thinned-aperture array in a center-mount, single-structure space frame. It employs speckle interferometric imaging to achieve diffraction-limited resolution. The signal-to-noise ratio problem is mitigated by moving the wavelength of operation to the near-IR, and the image is sensed by a Silicon CCD. The steerable, single-structure array presents a constant pupil. The center-mount, radar-like mount enables low-earth orbit space objects to be tracked as well as increases stiffness of the space frame. In the preferred embodiment, the array has elemental telescopes with subaperture of 2.1 m in a circle-of-nine configuration. The telescope array has an effective aperture of 12 m which provides a diffraction-limited resolution of 0.02 arc seconds. Pathlength matching of the telescope array is maintained by an electro-optical system employing laser metrology. Speckle imaging relaxes pathlength matching tolerance by one order of magnitude as compared to phased arrays. Many features of the telescope contribute to substantial reduction in costs. These include eliminating the conventional protective dome and reducing on-site construction activites. The cost of the telescope scales with the first power of the aperture rather than its third power as in conventional telescopes.
NASA Astrophysics Data System (ADS)
Mahmoud, Ahmed M.; Ngan, Peter; Crout, Richard; Mukdadi, Osama M.
2009-02-01
The use of ultrasound in dentistry is still an open growing area of research. Currently, there is a lack of imaging modalities to accurately predict minute structures and defects in the jawbone. In particular, the inability of 2D radiographic images to detect bony periodontal defects resulted from infection of the periodontium. This study investigates the feasibility of high frequency ultrasound to reconstruct high resolution 3D surface images of human jawbone. Methods: A dentate and non-dentate mandibles were used in this study. The system employs high frequency single-element ultrasound focused transducers (15-30 MHz) for scanning. Continuous acquisition using a 1 GHz data acquisition card is synchronized with a high precision two-dimensional stage positioning system of +/-1 μm resolution for acquiring accurate and quantitative measurements of the mandible in vitro. Radio frequency (RF) signals are acquired laterally 44-45.5 μm apart for each frame. Different frames are reconstructed 500 μm apart for the 3D reconstruction. Signal processing algorithms are applied on the received ultrasound signals for filtering, focusing, and envelope detection before frame reconstruction. Furthermore, an edge detection technique is adopted to detect the bone surface in each frame. Finally, all edges are combined together in order to render a 3D surface image of the jawbone. Major anatomical landmarks on the resultant images were confirmed with the anatomical structures on the mandibles to show the efficacy of the system. Comparison were also made with conventional 2D radiographs to show the superiority of the ultrasound imaging system in diagnosing small defects in the lateral, axial and elevation planes of space. Results: The landmarks on all ultrasound images matched with those on the mandible, indicating the efficacy of the system in detecting small structures in human jaw bones. Comparison with conventional 2D radiographic images of the same mandible showed superiority of the 3D ultrasound images in detecting defects in the elevation plane of space. These results suggest that the high frequency ultrasound system shows great potential in providing a non-invasive method to characterize the jawbone and detect periodontal diseases at earlier stages.
NASA Astrophysics Data System (ADS)
Yu, Liping; Pan, Bing
2017-08-01
Full-frame, high-speed 3D shape and deformation measurement using stereo-digital image correlation (stereo-DIC) technique and a single high-speed color camera is proposed. With the aid of a skillfully designed pseudo stereo-imaging apparatus, color images of a test object surface, composed of blue and red channel images from two different optical paths, are recorded by a high-speed color CMOS camera. The recorded color images can be separated into red and blue channel sub-images using a simple but effective color crosstalk correction method. These separated blue and red channel sub-images are processed by regular stereo-DIC method to retrieve full-field 3D shape and deformation on the test object surface. Compared with existing two-camera high-speed stereo-DIC or four-mirror-adapter-assisted singe-camera high-speed stereo-DIC, the proposed single-camera high-speed stereo-DIC technique offers prominent advantages of full-frame measurements using a single high-speed camera but without sacrificing its spatial resolution. Two real experiments, including shape measurement of a curved surface and vibration measurement of a Chinese double-side drum, demonstrated the effectiveness and accuracy of the proposed technique.
NASA Astrophysics Data System (ADS)
Hemenway, Paul
1991-07-01
Determination of a non-rotating Reference Frame is crucial to progress in many areas, including: Galactic motions, local (Oort's A and B) and global (R0) parameters derived from them, solar system motion discrepancies (Planet X); and in conjunction with the VLBI radio reference frame, the registration of radio and optical images at an accuracy well below the resolution limit of HST images (0.06 arcsec). The goal of the Program is to tie the HIPPARCOS and Extra- galactic Reference Frames together at the 0.0005 arcsec and 0.0005 arcsec/year level. The HST data will allow a deter- mination of the brightness distribution in the stellar and extragalactic objects observed and time dependent changes therein at the 0.001 arcsec/year level. The Program requires targets distributed over the whole sky to define a rigid Reference Frame. GTO observations will provide initial first epoch data and preliminary proper motions. The observations will consist of relative positions of Extra- galactic objects (EGOs) and HIPPARCOS stars, measured with the FGSs.
High-Speed Binary-Output Image Sensor
NASA Technical Reports Server (NTRS)
Fossum, Eric; Panicacci, Roger A.; Kemeny, Sabrina E.; Jones, Peter D.
1996-01-01
Photodetector outputs digitized by circuitry on same integrated-circuit chip. Developmental special-purpose binary-output image sensor designed to capture up to 1,000 images per second, with resolution greater than 10 to the 6th power pixels per image. Lower-resolution but higher-frame-rate prototype of sensor contains 128 x 128 array of photodiodes on complementary metal oxide/semiconductor (CMOS) integrated-circuit chip. In application for which it is being developed, sensor used to examine helicopter oil to determine whether amount of metal and sand in oil sufficient to warrant replacement.
ALMA resolves extended star formation in high-z AGN host galaxies
NASA Astrophysics Data System (ADS)
Harrison, C. M.; Simpson, J. M.; Stanley, F.; Alexander, D. M.; Daddi, E.; Mullaney, J. R.; Pannella, M.; Rosario, D. J.; Smail, Ian
2016-03-01
We present high-resolution (0.3 arcsec) Atacama Large Millimeter Array (ALMA) 870 μm imaging of five z ≈ 1.5-4.5 X-ray detected AGN (with luminosities of L2-8keV > 1042 erg s-1). These data provide a ≳20 times improvement in spatial resolution over single-dish rest-frame far-infrared (FIR) measurements. The sub-millimetre emission is extended on scales of FWHM ≈ 0.2 arcsec-0.5 arcsec, corresponding to physical sizes of 1-3 kpc (median value of 1.8 kpc). These sizes are comparable to the majority of z=1-5 sub-millimetre galaxies (SMGs) with equivalent ALMA measurements. In combination with spectral energy distribution analyses, we attribute this rest-frame FIR emission to dust heated by star formation. The implied star-formation rate surface densities are ≈20-200 M⊙ yr-1 kpc-2, which are consistent with SMGs of comparable FIR luminosities (I.e. LIR ≈ [1-5] × 1012 L⊙). Although limited by a small sample of AGN, which all have high-FIR luminosities, our study suggests that the kpc-scale spatial distribution and surface density of star formation in high-redshift star-forming galaxies is the same irrespective of the presence of X-ray detected AGN.
NASA Astrophysics Data System (ADS)
Antolovic, Ivan Michel; Burri, Samuel; Bruschini, Claudio; Hoebe, Ron; Charbon, Edoardo
2016-02-01
For many scientific applications, electron multiplying charge coupled devices (EMCCDs) have been the sensor of choice because of their high quantum efficiency and built-in electron amplification. Lately, many researchers introduced scientific complementary metal-oxide semiconductor (sCMOS) imagers in their instrumentation, so as to take advantage of faster readout and the absence of excess noise. Alternatively, single-photon avalanche diode (SPAD) imagers can provide even faster frame rates and zero readout noise. SwissSPAD is a 1-bit 512×128 SPAD imager, one of the largest of its kind, featuring a frame duration of 6.4 μs. Additionally, a gating mechanism enables photosensitive windows as short as 5 ns with a skew better than 150 ps across the entire array. The SwissSPAD photon detection efficiency (PDE) uniformity is very high, thanks on one side to a photon-to-digital conversion and on the other to a reduced fraction of "hot pixels" or "screamers", which would pollute the image with noise. A low native fill factor was recovered to a large extent using a microlens array, leading to a maximum PDE increase of 12×. This enabled us to detect single fluorophores, as required by ground state depletion followed by individual molecule return imaging microscopy (GSDIM). We show the first super resolution results obtained with a SPAD imager, with an estimated localization uncertainty of 30 nm and resolution of 100 nm. The high time resolution of 6.4 μs can be utilized to explore the dye's photophysics or for dye optimization. We also present the methodology for the blinking analysis on experimental data.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Reza Akrami, Seyed Mohammad; Miyata, Kazuki; Asakawa, Hitoshi
High-speed atomic force microscopy has attracted much attention due to its unique capability of visualizing nanoscale dynamic processes at a solid/liquid interface. However, its usability and resolution have yet to be improved. As one of the solutions for this issue, here we present a design of a high-speed Z-tip scanner with screw holding mechanism. We perform detailed comparison between designs with different actuator size and screw arrangement by finite element analysis. Based on the design giving the best performance, we have developed a Z tip scanner and measured its performance. The measured frequency response of the scanner shows a flatmore » response up to ∼10 kHz. This high frequency response allows us to achieve wideband tip-sample distance regulation. We demonstrate the applicability of the scanner to high-speed atomic-resolution imaging by visualizing atomic-scale calcite crystal dissolution process in water at 2 s/frame.« less
High-resolution surface analysis for extended-range downscaling with limited-area atmospheric models
NASA Astrophysics Data System (ADS)
Separovic, Leo; Husain, Syed Zahid; Yu, Wei; Fernig, David
2014-12-01
High-resolution limited-area model (LAM) simulations are frequently employed to downscale coarse-resolution objective analyses over a specified area of the globe using high-resolution computational grids. When LAMs are integrated over extended time frames, from months to years, they are prone to deviations in land surface variables that can be harmful to the quality of the simulated near-surface fields. Nudging of the prognostic surface fields toward a reference-gridded data set is therefore devised in order to prevent the atmospheric model from diverging from the expected values. This paper presents a method to generate high-resolution analyses of land-surface variables, such as surface canopy temperature, soil moisture, and snow conditions, to be used for the relaxation of lower boundary conditions in extended-range LAM simulations. The proposed method is based on performing offline simulations with an external surface model, forced with the near-surface meteorological fields derived from short-range forecast, operational analyses, and observed temperatures and humidity. Results show that the outputs of the surface model obtained in the present study have potential to improve the near-surface atmospheric fields in extended-range LAM integrations.
Hu, Dandan; Sarder, Pinaki; Ronhovde, Peter; Orthaus, Sandra; Achilefu, Samuel; Nussinov, Zohar
2014-01-01
Inspired by a multi-resolution community detection (MCD) based network segmentation method, we suggest an automatic method for segmenting fluorescence lifetime (FLT) imaging microscopy (FLIM) images of cells in a first pilot investigation on two selected images. The image processing problem is framed as identifying segments with respective average FLTs against the background in FLIM images. The proposed method segments a FLIM image for a given resolution of the network defined using image pixels as the nodes and similarity between the FLTs of the pixels as the edges. In the resulting segmentation, low network resolution leads to larger segments, and high network resolution leads to smaller segments. Further, using the proposed method, the mean-square error (MSE) in estimating the FLT segments in a FLIM image was found to consistently decrease with increasing resolution of the corresponding network. The MCD method appeared to perform better than a popular spectral clustering based method in performing FLIM image segmentation. At high resolution, the spectral segmentation method introduced noisy segments in its output, and it was unable to achieve a consistent decrease in MSE with increasing resolution. PMID:24251410
Video Completion in Digital Stabilization Task Using Pseudo-Panoramic Technique
NASA Astrophysics Data System (ADS)
Favorskaya, M. N.; Buryachenko, V. V.; Zotin, A. G.; Pakhirka, A. I.
2017-05-01
Video completion is a necessary stage after stabilization of a non-stationary video sequence, if it is desirable to make the resolution of the stabilized frames equalled the resolution of the original frames. Usually the cropped stabilized frames lose 10-20% of area that means the worse visibility of the reconstructed scenes. The extension of a view of field may appear due to the pan-tilt-zoom unwanted camera movement. Our approach deals with a preparing of pseudo-panoramic key frame during a stabilization stage as a pre-processing step for the following inpainting. It is based on a multi-layered representation of each frame including the background and objects, moving differently. The proposed algorithm involves four steps, such as the background completion, local motion inpainting, local warping, and seamless blending. Our experiments show that a necessity of a seamless stitching occurs often than a local warping step. Therefore, a seamless blending was investigated in details including four main categories, such as feathering-based, pyramid-based, gradient-based, and optimal seam-based blending.
Bullen, A; Patel, S S; Saggau, P
1997-07-01
The design and implementation of a high-speed, random-access, laser-scanning fluorescence microscope configured to record fast physiological signals from small neuronal structures with high spatiotemporal resolution is presented. The laser-scanning capability of this nonimaging microscope is provided by two orthogonal acousto-optic deflectors under computer control. Each scanning point can be randomly accessed and has a positioning time of 3-5 microseconds. Sampling time is also computer-controlled and can be varied to maximize the signal-to-noise ratio. Acquisition rates up to 200k samples/s at 16-bit digitizing resolution are possible. The spatial resolution of this instrument is determined by the minimal spot size at the level of the preparation (i.e., 2-7 microns). Scanning points are selected interactively from a reference image collected with differential interference contrast optics and a video camera. Frame rates up to 5 kHz are easily attainable. Intrinsic variations in laser light intensity and scanning spot brightness are overcome by an on-line signal-processing scheme. Representative records obtained with this instrument by using voltage-sensitive dyes and calcium indicators demonstrate the ability to make fast, high-fidelity measurements of membrane potential and intracellular calcium at high spatial resolution (2 microns) without any temporal averaging.
Bullen, A; Patel, S S; Saggau, P
1997-01-01
The design and implementation of a high-speed, random-access, laser-scanning fluorescence microscope configured to record fast physiological signals from small neuronal structures with high spatiotemporal resolution is presented. The laser-scanning capability of this nonimaging microscope is provided by two orthogonal acousto-optic deflectors under computer control. Each scanning point can be randomly accessed and has a positioning time of 3-5 microseconds. Sampling time is also computer-controlled and can be varied to maximize the signal-to-noise ratio. Acquisition rates up to 200k samples/s at 16-bit digitizing resolution are possible. The spatial resolution of this instrument is determined by the minimal spot size at the level of the preparation (i.e., 2-7 microns). Scanning points are selected interactively from a reference image collected with differential interference contrast optics and a video camera. Frame rates up to 5 kHz are easily attainable. Intrinsic variations in laser light intensity and scanning spot brightness are overcome by an on-line signal-processing scheme. Representative records obtained with this instrument by using voltage-sensitive dyes and calcium indicators demonstrate the ability to make fast, high-fidelity measurements of membrane potential and intracellular calcium at high spatial resolution (2 microns) without any temporal averaging. Images FIGURE 6 PMID:9199810
NASA Astrophysics Data System (ADS)
Simpson, J. M.; Smail, Ian; Wang, Wei-Hao; Riechers, D.; Dunlop, J. S.; Ao, Y.; Bourne, N.; Bunker, A.; Chapman, S. C.; Chen, Chian-Chou; Dannerbauer, H.; Geach, J. E.; Goto, T.; Harrison, C. M.; Hwang, H. S.; Ivison, R. J.; Kodama, Tadayuki; Lee, C.-H.; Lee, H.-M.; Lee, M.; Lim, C.-F.; Michałowski, M. J.; Rosario, D. J.; Shim, H.; Shu, X. W.; Swinbank, A. M.; Tee, W.-L.; Toba, Y.; Valiante, E.; Wang, Junxian; Zheng, X. Z.
2017-07-01
The identification of high-redshift, massive galaxies with old stellar populations may pose challenges to some models of galaxy formation. However, to securely classify a galaxy as quiescent, it is necessary to exclude significant ongoing star formation, something that can be challenging to achieve at high redshifts. In this Letter, we analyze deep ALMA/870 μm and SCUBA-2/450 μm imaging of the claimed “post-starburst” galaxy ZF 20115 at z = 3.717 that exhibits a strong Balmer break and absorption lines. The rest-frame far-infrared imaging identifies a luminous starburst 0.″4 ± 0.″1 (˜3 kpc in projection) from the position of the ultraviolet/optical emission and is consistent with lying at the redshift of ZF 20115. The star-forming component, with an obscured star formation rate of {100}-70+15 {M}⊙ {{yr}}-1, is undetected in the rest-frame ultraviolet but contributes significantly to the lower angular resolution photometry at rest-frame wavelengths ≳3500 Å. This contribution from the obscured starburst, especially in the Spitzer/IRAC wavebands, significantly complicates the determination of a reliable stellar mass for the ZF 20015 system, and we conclude that this source does not pose a challenge to current models of galaxy formation. The multi-wavelength observations of ZF 20115 unveil a complex system with an intricate and spatially varying star formation history. ZF 20115 demonstrates that understanding high-redshift obscured starbursts will only be possible with multi-wavelength studies that include high-resolution observations, available with the James Webb Space Telescope, at mid-infrared wavelengths.
Framing U-Net via Deep Convolutional Framelets: Application to Sparse-View CT.
Han, Yoseob; Ye, Jong Chul
2018-06-01
X-ray computed tomography (CT) using sparse projection views is a recent approach to reduce the radiation dose. However, due to the insufficient projection views, an analytic reconstruction approach using the filtered back projection (FBP) produces severe streaking artifacts. Recently, deep learning approaches using large receptive field neural networks such as U-Net have demonstrated impressive performance for sparse-view CT reconstruction. However, theoretical justification is still lacking. Inspired by the recent theory of deep convolutional framelets, the main goal of this paper is, therefore, to reveal the limitation of U-Net and propose new multi-resolution deep learning schemes. In particular, we show that the alternative U-Net variants such as dual frame and tight frame U-Nets satisfy the so-called frame condition which makes them better for effective recovery of high frequency edges in sparse-view CT. Using extensive experiments with real patient data set, we demonstrate that the new network architectures provide better reconstruction performance.
Li, Hao; Lu, Jing; Shi, Guohua; Zhang, Yudong
2010-01-01
With the use of adaptive optics (AO), high-resolution microscopic imaging of living human retina in the single cell level has been achieved. In an adaptive optics confocal scanning laser ophthalmoscope (AOSLO) system, with a small field size (about 1 degree, 280 μm), the motion of the eye severely affects the stabilization of the real-time video images and results in significant distortions of the retina images. In this paper, Scale-Invariant Feature Transform (SIFT) is used to abstract stable point features from the retina images. Kanade-Lucas-Tomasi(KLT) algorithm is applied to track the features. With the tracked features, the image distortion in each frame is removed by the second-order polynomial transformation, and 10 successive frames are co-added to enhance the image quality. Features of special interest in an image can also be selected manually and tracked by KLT. A point on a cone is selected manually, and the cone is tracked from frame to frame. PMID:21258443
NASA Astrophysics Data System (ADS)
Jacobs, Alan M.; Cox, John D.; Juang, Yi-Shung
1987-01-01
A solid-state digital x-ray detector is described which can replace high resolution film in industrial radiography and has potential for application in some medical imaging. Because of the 10 micron pixel pitch on the sensor, contact magnification radiology is possible and is demonstrated. Methods for frame speed increase and integration of sensor to a large format are discussed.
A video event trigger for high frame rate, high resolution video technology
NASA Astrophysics Data System (ADS)
Williams, Glenn L.
1991-12-01
When video replaces film the digitized video data accumulates very rapidly, leading to a difficult and costly data storage problem. One solution exists for cases when the video images represent continuously repetitive 'static scenes' containing negligible activity, occasionally interrupted by short events of interest. Minutes or hours of redundant video frames can be ignored, and not stored, until activity begins. A new, highly parallel digital state machine generates a digital trigger signal at the onset of a video event. High capacity random access memory storage coupled with newly available fuzzy logic devices permits the monitoring of a video image stream for long term or short term changes caused by spatial translation, dilation, appearance, disappearance, or color change in a video object. Pretrigger and post-trigger storage techniques are then adaptable for archiving the digital stream from only the significant video images.
A video event trigger for high frame rate, high resolution video technology
NASA Technical Reports Server (NTRS)
Williams, Glenn L.
1991-01-01
When video replaces film the digitized video data accumulates very rapidly, leading to a difficult and costly data storage problem. One solution exists for cases when the video images represent continuously repetitive 'static scenes' containing negligible activity, occasionally interrupted by short events of interest. Minutes or hours of redundant video frames can be ignored, and not stored, until activity begins. A new, highly parallel digital state machine generates a digital trigger signal at the onset of a video event. High capacity random access memory storage coupled with newly available fuzzy logic devices permits the monitoring of a video image stream for long term or short term changes caused by spatial translation, dilation, appearance, disappearance, or color change in a video object. Pretrigger and post-trigger storage techniques are then adaptable for archiving the digital stream from only the significant video images.
Distorted turbulence submitted to frame rotation: RDT and LES results
NASA Technical Reports Server (NTRS)
Godeferd, Fabien S.
1995-01-01
The objective of this effort is to carry the analysis of Lee et al. (1990) to the case of shear with rotation. We apply the RDT approximation to turbulence submitted to frame rotation for the case of a uniformly sheared flow and compare its mean statistics to results of high resolution DNS of a rotating plane channel flow. In the latter, the mean velocity profile is modified by the Coriolis force, and accordingly, different regions in the channel can be identified. The properties of the plane pure strain turbulence submitted to frame rotation are, in addition, investigated in spectral space, which shows the usefulness of the spectral RDT approach. This latter case is investigated here. Among the general class of quadratic flows, this case does not follow the same stability properties as the others since the related mean vorticity is zero.
Mejía-Díaz, Diana Margarita; Carmona-Garcés, Isabel Cristina; Giraldo-López, Paula Andrea; González-Zapata, Laura
2014-04-01
To describe the nutritional content of foods and non-alcoholic beverages advertised in the children's frame vs. the general frame in two national, private, free-access, television channels in Colombia. Cross-sectional, descriptive study. The recording was performed in July of 2012, for four days randomly chosen from 6:00 am to 12:30 pm. The nutritional content was classified according to the nutritional profiles criteria of the Food Standards Agency for risk-indicating nutrients, the Health Pan-American Organization for trans fat, and the 333 Colombian Resolution of 2011 that classifies foods as source of protecting nutrients. Descriptive statistics were used, the Kolmogorov-Smirnov test to establish the normality, and the Chi square test for variables comparison. A p value < 0.05 was considered. During 52 hours of recording, 1560 commercials were shown, of which 23.3% (364), advertised foods and beverages, of which 56.3% were shown within the children's frame. Regarding the nutritional content, a high percentage of foods and non-alcoholic beverages classified as "rich" in sugar, sodium, saturated fat was observed within the children's' frame (69.0%, 56.0%, 57.1%), as compared to the general frame. By contrast, the percentage of foods and nonalcoholic beverages classified as "rich" in total fat was higher in the general frame as compared to the children's frame (70.4% vs. 29.6%, respectively). Higher exposure to advertising of foods and non-alcoholic beverages was observed within the children's' frame, characterized by high content of risk-indicating nutrients and low content of foods and non-alcoholic beverages with protective nutrients. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
4 Vesta in Color: High Resolution Mapping from Dawn Framing Camera Images
NASA Technical Reports Server (NTRS)
Reddy, V.; LeCorre, L.; Nathues, A.; Sierks, H.; Christensen, U.; Hoffmann, M.; Schroeder, S. E.; Vincent, J. B.; McSween, H. Y.; Denevi, B. W.;
2011-01-01
Rotational surface variations on asteroid 4 Vesta have been known from ground-based and HST observations, and they have been interpreted as evidence of compositional diversity. NASA s Dawn mission entered orbit around Vesta on July 16, 2011 for a year-long global characterization. The framing cameras (FC) onboard the Dawn spacecraft will image the asteroid in one clear (broad) and seven narrow band filters covering the wavelength range between 0.4-1.0 microns. We present color mapping results from the Dawn FC observations of Vesta obtained during Survey orbit (approx.3000 km) and High-Altitude Mapping Orbit (HAMO) (approx.950 km). Our aim is to create global color maps of Vesta using multi spectral FC images to identify the spatial extent of compositional units and link them with other available data sets to extract the basic mineralogy. While the VIR spectrometer onboard Dawn has higher spectral resolution (864 channels) allowing precise mineralogical assessment of Vesta s surface, the FC has three times higher spatial resolution in any given orbital phase. In an effort to extract maximum information from FC data we have developed algorithms using laboratory spectra of pyroxenes and HED meteorites to derive parameters associated with the 1-micron absorption band wing. These parameters will help map the global distribution of compositionally related units on Vesta s surface. Interpretation of these units will involve the integration of FC and VIR data.
A distributed automatic target recognition system using multiple low resolution sensors
NASA Astrophysics Data System (ADS)
Yue, Zhanfeng; Lakshmi Narasimha, Pramod; Topiwala, Pankaj
2008-04-01
In this paper, we propose a multi-agent system which uses swarming techniques to perform high accuracy Automatic Target Recognition (ATR) in a distributed manner. The proposed system can co-operatively share the information from low-resolution images of different looks and use this information to perform high accuracy ATR. An advanced, multiple-agent Unmanned Aerial Vehicle (UAV) systems-based approach is proposed which integrates the processing capabilities, combines detection reporting with live video exchange, and swarm behavior modalities that dramatically surpass individual sensor system performance levels. We employ real-time block-based motion analysis and compensation scheme for efficient estimation and correction of camera jitter, global motion of the camera/scene and the effects of atmospheric turbulence. Our optimized Partition Weighted Sum (PWS) approach requires only bitshifts and additions, yet achieves a stunning 16X pixel resolution enhancement, which is moreover parallizable. We develop advanced, adaptive particle-filtering based algorithms to robustly track multiple mobile targets by adaptively changing the appearance model of the selected targets. The collaborative ATR system utilizes the homographies between the sensors induced by the ground plane to overlap the local observation with the received images from other UAVs. The motion of the UAVs distorts estimated homography frame to frame. A robust dynamic homography estimation algorithm is proposed to address this, by using the homography decomposition and the ground plane surface estimation.
Resolution enhancement of pump-probe microscope with an inverse-annular filter
NASA Astrophysics Data System (ADS)
Kobayashi, Takayoshi; Kawasumi, Koshi; Miyazaki, Jun; Nakata, Kazuaki
2018-04-01
Optical pump-probe microscopy can provide images by detecting changes in probe light intensity induced by stimulated emission, photoinduced absorbance change, or photothermal-induced refractive index change in either transmission or reflection mode. Photothermal microscopy, which is one type of optical pump-probe microscopy, has intrinsically super resolution capability due to the bilinear dependence of signal intensity of pump and probe. We introduce new techniques for further resolution enhancement and fast imaging in photothermal microscope. First, we introduce a new pupil filter, an inverse-annular pupil filter in a pump-probe photothermal microscope, which provides resolution enhancement in three dimensions. The resolutions are proved to be improved in lateral and axial directions by imaging experiment using 20-nm gold nanoparticles. The improvement in X (perpendicular to the common pump and probe polarization direction), Y (parallel to the polarization direction), and Z (axial direction) are by 15 ± 6, 8 ± 8, and 21 ± 2% from the resolution without a pupil filter. The resolution enhancement is even better than the calculation using vector field, which predicts the corresponding enhancement of 11, 8, and 6%. The discussion is made to explain the unexpected results. We also demonstrate the photothermal imaging of thick biological samples (cells from rabbit intestine and kidney) stained with hematoxylin and eosin dye with the inverse-annular filter. Second, a fast, high-sensitivity photothermal microscope is developed by implementing a spatially segmented balanced detection scheme into a laser scanning microscope using a Galvano mirror. We confirm a 4.9 times improvement in signal-to-noise ratio in the spatially segmented balanced detection compared with that of conventional detection. The system demonstrates simultaneous bi-modal photothermal and confocal fluorescence imaging of transgenic mouse brain tissue with a pixel dwell time of 20 µs. The fluorescence image visualizes neurons expressing yellow fluorescence proteins, while the photothermal signal detected endogenous chromophores in the mouse brain, allowing 3D visualization of the distribution of various features such as blood cells and fine structures most probably due to lipids. This imaging modality was constructed using compact and cost-effective laser diodes, and will thus be widely useful in the life and medical sciences. Third, we have made further resolution improvement of high-sensitivity laser scanning photothermal microscopy by applying non-linear detection. By this, the new method has super resolution with 61 and 42% enhancement from the diffraction limit values of the probe and pump wavelengths, respectively, by a second-order non-linear scheme and a high-frame rate in a laser scanning microscope. The maximum resolution is determined to be 160 nm in the second-order non-linear detection mode and 270 nm in the linear detection mode by the PT signal of GNPs. The pixel rate and frame rate for 300 × 300 pixel image are 50 µs and 4.5 s, respectively. The pixel and frame rate are shorter than the rates, those are 1 ms and 100 s, using the piezo-driven stage system.
Novel high-resolution VGA QWIP detector
NASA Astrophysics Data System (ADS)
Kataria, H.; Asplund, C.; Lindberg, A.; Smuk, S.; Alverbro, J.; Evans, D.; Sehlin, S.; Becanovic, S.; Tinghag, P.; Höglund, L.; Sjöström, F.; Costard, E.
2017-02-01
Continuing with its legacy of producing high performance infrared detectors, IRnova introduces its high resolution LWIR IDDCA (Integrated Detector Dewar Cooler assembly) based on QWIP (quantum well infrared photodetector) technology. The Focal Plane Array (FPA) has 640×512 pixels, with small (15μm) pixel pitch, and is based on the FLIRIndigo ISC0403 Readout Integrated Circuit (ROIC). The QWIP epitaxial structures are grown by metal-organic vapor phase epitaxy (MOVPE) at IRnova. Detector stability and response uniformity inherent to III/V based material will be demonstrated in terms of high performing detectors. Results showing low NETD at high frame rate will be presented. This makes it one of the first 15μm pitch QWIP based LWIR IDDCA commercially available on the market. High operability and stability of our other QWIP based products will also be shared.
Zonal wavefront sensing with enhanced spatial resolution.
Pathak, Biswajit; Boruah, Bosanta R
2016-12-01
In this Letter, we introduce a scheme to enhance the spatial resolution of a zonal wavefront sensor. The zonal wavefront sensor comprises an array of binary gratings implemented by a ferroelectric spatial light modulator (FLCSLM) followed by a lens, in lieu of the array of lenses in the Shack-Hartmann wavefront sensor. We show that the fast response of the FLCSLM device facilitates quick display of several laterally shifted binary grating patterns, and the programmability of the device enables simultaneous capturing of each focal spot array. This eventually leads to a wavefront estimation with an enhanced spatial resolution without much sacrifice on the sensor frame rate, thus making the scheme suitable for high spatial resolution measurement of transient wavefronts. We present experimental and numerical simulation results to demonstrate the importance of the proposed wavefront sensing scheme.
Manassakorn, Anita; Ishikawa, Hiroshi; Kim, Jong S.; Wollstein, Gadi; Bilonick, Richard A.; Kagemann, Larry; Gabriele, Michelle L.; Sung, Kyung Rim; Mumcuoglu, Tarkan; Duker, Jay S.; Fujimoto, James G.; Schuman, Joel S.
2009-01-01
Objective To determine the correspondence between optic disc margins evaluated using disc photography (DP) and optical coherence tomography (OCT). Methods From May 1, 2005, through November 10, 2005, 17 healthy volunteers (17 eyes) had raster scans (180 frames, 501 samplings per frame) centered on the optic disc taken with stereo-optic DP and high-speed ultrahigh-resolution OCT (hsUHR-OCT). Two image outputs were derived from the hsUHR-OCT data set: an en face hsUHR-OCT fundus image and a set of 180 frames of cross-sectional images. Three ophthalmologists independently and in a masked, randomized fashion marked the disc margin on the DP, hsUHR-OCT fundus, and cross-sectional images using custom software. Disc size (area and horizontal and vertical diameters) and location of the geometric disc center were compared among the 3 types of images. Results The hsUHR-OCT fundus image definition showed a significantly smaller disc size than the DP definition (P<.001, mixed-effects analysis). The hsUHR-OCT cross-sectional image definition showed a significantly larger disc size than the DP definition (P<.001). The geometric disc center location was similar among the 3 types of images except for the y-coordinate, which was significantly smaller in the hsUHR-OCT fundus images than in the DP images. Conclusion The optic disc margin as defined by hsUHR-OCT was significantly different than the margin defined by DP. PMID:18195219
Motion-compensated compressed sensing for dynamic imaging
NASA Astrophysics Data System (ADS)
Sundaresan, Rajagopalan; Kim, Yookyung; Nadar, Mariappan S.; Bilgin, Ali
2010-08-01
The recently introduced Compressed Sensing (CS) theory explains how sparse or compressible signals can be reconstructed from far fewer samples than what was previously believed possible. The CS theory has attracted significant attention for applications such as Magnetic Resonance Imaging (MRI) where long acquisition times have been problematic. This is especially true for dynamic MRI applications where high spatio-temporal resolution is needed. For example, in cardiac cine MRI, it is desirable to acquire the whole cardiac volume within a single breath-hold in order to avoid artifacts due to respiratory motion. Conventional MRI techniques do not allow reconstruction of high resolution image sequences from such limited amount of data. Vaswani et al. recently proposed an extension of the CS framework to problems with partially known support (i.e. sparsity pattern). In their work, the problem of recursive reconstruction of time sequences of sparse signals was considered. Under the assumption that the support of the signal changes slowly over time, they proposed using the support of the previous frame as the "known" part of the support for the current frame. While this approach works well for image sequences with little or no motion, motion causes significant change in support between adjacent frames. In this paper, we illustrate how motion estimation and compensation techniques can be used to reconstruct more accurate estimates of support for image sequences with substantial motion (such as cardiac MRI). Experimental results using phantoms as well as real MRI data sets illustrate the improved performance of the proposed technique.
High-resolution Ceres LAMO atlas derived from Dawn FC images
NASA Astrophysics Data System (ADS)
Roatsch, T.; Kersten, E.; Matz, K. D.; Preusker, F.; Scholten, F.; Jaumann, R.; Raymond, C. A.; Russell, C.
2016-12-01
Introduction: NASA's Dawn spacecraft has been orbiting the dwarf planet Ceres since December 2015 in LAMO (High Altitude Mapping Orbit) with an altitude of about 400 km to characterize for instance the geology, topography, and shape of Ceres. One of the major goals of this mission phase is the global high-resolution mapping of Ceres. Data: The Dawn mission is equipped with a fram-ing camera (FC). The framing camera took until the time of writing about 27,500 clear filter images in LAMO with a resolution of about 30 m/pixel and dif-ferent viewing angles and different illumination condi-tions. Data Processing: The first step of the processing chain towards the cartographic products is to ortho-rectify the images to the proper scale and map projec-tion type. This process requires detailed information of the Dawn orbit and attitude data and of the topography of the target. A high-resolution shape model was provided by stereo processing of the HAMO dataset, orbit and attitude data are available as reconstructed SPICE data. Ceres' HAMO shape model is used for the calculation of the ray intersection points while the map projection itself was done onto a reference sphere of Ceres. The final step is the controlled mosaicking of all nadir images to a global mosaic of Ceres, the so called basemap. Ceres map tiles: The Ceres atlas will be produced in a scale of 1:250,000 and will consist of 62 tiles that conforms to the quadrangle schema for Venus at 1:5,000,000. A map scale of 1:250,000 is a compro-mise between the very high resolution in LAMO and a proper map sheet size of the single tiles. Nomenclature: The Dawn team proposed to the International Astronomical Union (IAU) to use the names of gods and goddesses of agriculture and vege-tation from world mythology as names for the craters and to use names of agricultural festivals of the world for other geological features. This proposal was ac-cepted by the IAU and the team proposed 92 names for geological features to the IAU based on the LAMO mosaic. These feature names will be applied to the map tiles.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bhardwaj, Anshul; Casjens, Sherwood R.; Cingolani, Gino, E-mail: gino.cingolani@jefferson.edu
2014-02-01
This study presents the crystal structure of a ∼320 Å long protein fiber generated by in-frame extension of its repeated helical coiled-coil core. Protein fibers are widespread in nature, but only a limited number of high-resolution structures have been determined experimentally. Unlike globular proteins, fibers are usually recalcitrant to form three-dimensional crystals, preventing single-crystal X-ray diffraction analysis. In the absence of three-dimensional crystals, X-ray fiber diffraction is a powerful tool to determine the internal symmetry of a fiber, but it rarely yields atomic resolution structural information on complex protein fibers. An 85-residue-long minimal coiled-coil repeat unit (MiCRU) was previously identifiedmore » in the trimeric helical core of tail needle gp26, a fibrous protein emanating from the tail apparatus of the bacteriophage P22 virion. Here, evidence is provided that an MiCRU can be inserted in frame inside the gp26 helical core to generate a rationally extended fiber (gp26-2M) which, like gp26, retains a trimeric quaternary structure in solution. The 2.7 Å resolution crystal structure of this engineered fiber, which measures ∼320 Å in length and is only 20–35 Å wide, was determined. This structure, the longest for a trimeric protein fiber to be determined to such a high resolution, reveals the architecture of 22 consecutive trimerization heptads and provides a framework to decipher the structural determinants for protein fiber assembly, stability and flexibility.« less
1920x1080 pixel color camera with progressive scan at 50 to 60 frames per second
NASA Astrophysics Data System (ADS)
Glenn, William E.; Marcinka, John W.
1998-09-01
For over a decade, the broadcast industry, the film industry and the computer industry have had a long-range objective to originate high definition images with progressive scan. This produces images with better vertical resolution and much fewer artifacts than interlaced scan. Computers almost universally use progressive scan. The broadcast industry has resisted switching from interlace to progressive because no cameras were available in that format with the 1920 X 1080 resolution that had obtained international acceptance for high definition program production. The camera described in this paper produces an output in that format derived from two 1920 X 1080 CCD sensors produced by Eastman Kodak.
2004-08-01
on a pair of high -resolution, LCD medical monitors. The change to the new workstation has required us to rewrite the software... In the original CRT-based system, the two 7 images forming a stereo pair were displayed alternately on the same CRT face, at a high frame rate (120 Hz...then, separately, receive the stereo screening exam on the research GE digital mammography unit.
An observation of prominence condensation out of a coronal void
NASA Astrophysics Data System (ADS)
Wagner, W. J.; Newkirk, G., Jr.; Schmidt, H. U.
1983-02-01
Photographic averaging of cine-camera data-frames from the 7 March 1970 eclipse provided a record of the inner white light corona with unusually high resolution for low-contrast features. The authors report that a coronal void, similar to high corona structures associated with prominence formation (MacQueen et al., 1983), extended low into the corona. During eclipse totality, a coronal rain prominence condensed from the base of the void.
Ruschin, Mark; Komljenovic, Philip T; Ansell, Steve; Ménard, Cynthia; Bootsma, Gregory; Cho, Young-Bin; Chung, Caroline; Jaffray, David
2013-01-01
Image guidance has improved the precision of fractionated radiation treatment delivery on linear accelerators. Precise radiation delivery is particularly critical when high doses are delivered to complex shapes with steep dose gradients near critical structures, as is the case for intracranial radiosurgery. To reduce potential geometric uncertainties, a cone beam computed tomography (CT) image guidance system was developed in-house to generate high-resolution images of the head at the time of treatment, using a dedicated radiosurgery unit. The performance and initial clinical use of this imaging system are described. A kilovoltage cone beam CT system was integrated with a Leksell Gamma Knife Perfexion radiosurgery unit. The X-ray tube and flat-panel detector are mounted on a translational arm, which is parked above the treatment unit when not in use. Upon descent, a rotational axis provides 210° of rotation for cone beam CT scans. Mechanical integrity of the system was evaluated over a 6-month period. Subsequent clinical commissioning included end-to-end testing of targeting performance and subjective image quality performance in phantoms. The system has been used to image 2 patients, 1 of whom received single-fraction radiosurgery and 1 who received 3 fractions, using a relocatable head frame. Images of phantoms demonstrated soft tissue contrast visibility and submillimeter spatial resolution. A contrast difference of 35 HU was easily detected at a calibration dose of 1.2 cGy (center of head phantom). The shape of the mechanical flex vs scan angle was highly reproducible and exhibited <0.2 mm peak-to-peak variation. With a 0.5-mm voxel pitch, the maximum targeting error was 0.4 mm. Images of 2 patients were analyzed offline and submillimeter agreement was confirmed with conventional frame. A cone beam CT image guidance system was successfully adapted to a radiosurgery unit. The system is capable of producing high-resolution images of bone and soft tissue. The system is in clinical use and provides excellent image guidance without invasive frames. Copyright © 2013 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Bu, Haifeng; Wang, Dansheng; Zhou, Pin; Zhu, Hongping
2018-04-01
An improved wavelet-Galerkin (IWG) method based on the Daubechies wavelet is proposed for reconstructing the dynamic responses of shear structures. The proposed method flexibly manages wavelet resolution level according to excitation, thereby avoiding the weakness of the wavelet-Galerkin multiresolution analysis (WGMA) method in terms of resolution and the requirement of external excitation. IWG is implemented by this work in certain case studies, involving single- and n-degree-of-freedom frame structures subjected to a determined discrete excitation. Results demonstrate that IWG performs better than WGMA in terms of accuracy and computation efficiency. Furthermore, a new method for parameter identification based on IWG and an optimization algorithm are also developed for shear frame structures, and a simultaneous identification of structural parameters and excitation is implemented. Numerical results demonstrate that the proposed identification method is effective for shear frame structures.
Optical coherence tomography imaging based on non-harmonic analysis
NASA Astrophysics Data System (ADS)
Cao, Xu; Hirobayashi, Shigeki; Chong, Changho; Morosawa, Atsushi; Totsuka, Koki; Suzuki, Takuya
2009-11-01
A new processing technique called Non-Harmonic Analysis (NHA) is proposed for OCT imaging. Conventional Fourier-Domain OCT relies on the FFT calculation which depends on the window function and length. Axial resolution is counter proportional to the frame length of FFT that is limited by the swept range of the swept source in SS-OCT, or the pixel counts of CCD in SD-OCT degraded in FD-OCT. However, NHA process is intrinsically free from this trade-offs; NHA can resolve high frequency without being influenced by window function or frame length of sampled data. In this study, NHA process is explained and applied to OCT imaging and compared with OCT images based on FFT. In order to validate the benefit of NHA in OCT, we carried out OCT imaging based on NHA with the three different sample of onion-skin,human-skin and pig-eye. The results show that NHA process can realize practical image resolution that is equivalent to 100nm swept range only with less than half-reduced wavelength range.
Nagel, S. R.; Benedetti, L. R.; Bradley, D. K.; ...
2016-08-05
The dilation x-ray imager (DIXI) is a high-speed x-ray framing camera that uses the pulse-dilation technique to achieve a temporal resolution of less than 10 ps. This is a 10× improvement over conventional framing cameras currently employed on the National Ignition Facility (NIF) (100 ps resolution), and otherwise only achievable with 1D streaked imaging. A side effect of the dramatically reduced gate width is the comparatively lower detected signal level. Therefore we implement a Poisson noise reduction with non-local principal component analysis method to improve the robustness of the DIXI data analysis. Furthermore, we present results on ignition-relevant experiments atmore » the NIF using DIXI. In particular we focus on establishing that/when DIXI gives reliable shape metrics (P 0, P 2 and P 4 Legendre modes, and their temporal evolution/swings).« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nagel, S. R.; Benedetti, L. R.; Bradley, D. K.
The dilation x-ray imager (DIXI) is a high-speed x-ray framing camera that uses the pulse-dilation technique to achieve a temporal resolution of less than 10 ps. This is a 10× improvement over conventional framing cameras currently employed on the National Ignition Facility (NIF) (100 ps resolution), and otherwise only achievable with 1D streaked imaging. A side effect of the dramatically reduced gate width is the comparatively lower detected signal level. Therefore we implement a Poisson noise reduction with non-local principal component analysis method to improve the robustness of the DIXI data analysis. Furthermore, we present results on ignition-relevant experiments atmore » the NIF using DIXI. In particular we focus on establishing that/when DIXI gives reliable shape metrics (P 0, P 2 and P 4 Legendre modes, and their temporal evolution/swings).« less
Insect Wing Displacement Measurement Using Digital Holography
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aguayo, Daniel D.; Mendoza Santoyo, Fernando; Torre I, Manuel H. de la
2008-04-15
Insects in flight have been studied with optical non destructive techniques with the purpose of using meaningful results in aerodynamics. With the availability of high resolution and large dynamic range CCD sensors the so called interferometric digital holographic technique was used to measure the surface displacement of in flight insect wings, such as butterflies. The wings were illuminated with a continuous wave Verdi laser at 532 nm, and observed with a CCD Pixelfly camera that acquire images at a rate of 11.5 frames per second at a resolution of 1392x1024 pixels and 12 Bit dynamic range. At this frame ratemore » digital holograms of the wings were captured and processed in the usual manner, namely, each individual hologram is Fourier processed in order to find the amplitude and phase corresponding to the digital hologram. The wings displacement is obtained when subtraction between two digital holograms is performed for two different wings position, a feature applied to all consecutive frames recorded. The result of subtracting is seen as a wrapped phase fringe pattern directly related to the wing displacement. The experimental data for different butterfly flying conditions and exposure times are shown as wire mesh plots in a movie of the wings displacement.« less
Intraoperative MR-guided DBS implantation for treating PD and ET
NASA Astrophysics Data System (ADS)
Liu, Haiying; Maxwell, Robert E.; Truwit, Charles L.
2001-05-01
Deep brain stimulator (DBS) implantation is a promising treatment alternative for suppressing the motor tremor symptoms in Parkinson disease (PD) patient. The main objective is to develop a minimally invasive approach using high spatial resolution and soft-tissue contrast MR imaging techniques to guide the surgical placement of DBS. In the MR-guided procedure, the high spatial resolution MR images were obtained intra-operatively and used to target stereotactically a specific deep brain location. The neurosurgery for craniotomy was performed in the front of the magnet outside of the 10 Gauss line. Aided with positional registration assembly for the stereotactic head frame, the target location (VIM or GPi or STN) in deep brain areas was identified and measured from the MR images in reference to the markers in the calibration assembly of the head frame before the burrhole prep. In 20 patients, MR- guided DBS implantations have been performed according to the new methodology. MR-guided DBS implantation at high magnetic field strength has been shown to be feasible and desirable. In addition to the improved outcome, this offers a new surgical approach in which intra-operative visualization is possible during intervention, and any complications such as bleeding can be assessed in situ immediately prior to dural closure.
How stakeholders frame dam removal: The role of current and anticipated future ecosystem service use
NASA Astrophysics Data System (ADS)
Reilly, Kate; Adamowski, Jan
2016-04-01
Many river restoration projects, including dam removal, are controversial and can trigger conflicts between stakeholders who are for and against the proposed project. The study of environmental conflicts suggests that differences in how stakeholders 'frame', or make sense of a situation based on their prior knowledge and experiences, can perpetuate conflicts. Understanding different stakeholders' frames, particularly how they converge, can form the basis of successful conflict resolution. In the case of dam removals, it is often assumed that emphasising increased provision of ecosystem services can be a point of convergence between those advocating for ecological restoration and those opposed to removal because of negative human impacts. However, how exactly stakeholders frame a contentious proposed dam removal and how those frames relate to ecosystem services has been little studied. Here we used the case of a potential dam removal in New Brunswick to investigate how people frame the issue and how that relates to their current and anticipated future use of ecosystem services. Based on in-depth interviews with 30 stakeholders in the area, including both people for and against dam removal, we found that both groups currently used ecosystem services and were in favour of ecosystem protection. However, they differed in how they framed the issue of the potential dam removal. The group against dam removal framed the issue as one of loss and risk - they thought that any potential benefits to the ecosystem would be outweighed by the high risk of negative social impacts caused by a loss of access to ecosystem services, such as recreation and aesthetic enjoyment. By contrast, the group in favour of the dam framed the issue as one of opportunity and justice. They thought that following a short transition period, all stakeholders would benefit from the restored river, particularly from a restored salmon fishery, improved aesthetic appeal and the long-term sustainability of an undammed river. Ultimately, we argue that increased provision of ecosystem services does not always represent a point of convergence between stakeholder groups, because both groups support ecosystem protection but differ in how they expect the benefits they derive from ecosystem services to change. Conflict resolution strategies may be better addressed by measures to mitigate the perceived loss of ecosystem services in the group against dam removal.
3D super resolution range-gated imaging for canopy reconstruction and measurement
NASA Astrophysics Data System (ADS)
Huang, Hantao; Wang, Xinwei; Sun, Liang; Lei, Pingshun; Fan, Songtao; Zhou, Yan
2018-01-01
In this paper, we proposed a method of canopy reconstruction and measurement based on 3D super resolution range-gated imaging. In this method, high resolution 2D intensity images are grasped by active gate imaging, and 3D images of canopy are reconstructed by triangular-range-intensity correlation algorithm at the same time. A range-gated laser imaging system(RGLIS) is established based on 808 nm diode laser and gated intensified charge-coupled device (ICCD) camera with 1392´1040 pixels. The proof experiments have been performed for potted plants located 75m away and trees located 165m away. The experiments show it that can acquire more than 1 million points per frame, and 3D imaging has the spatial resolution about 0.3mm at the distance of 75m and the distance accuracy about 10 cm. This research is beneficial for high speed acquisition of canopy structure and non-destructive canopy measurement.
Development of Residual Gas Profile Monitors at GSI
NASA Astrophysics Data System (ADS)
Giacomini, T.; Barabin, S.; Forck, P.; Liakin, D.; Skachkov, V.
2004-11-01
Beam profile measurements at modern ion synchrotrons and storage rings require high timing performances on a turn-by-turn basis. High spatial resolutions are essential for cold beams and beamwidth measurings. The currently used RGM supported very interesting measurements and applications. Due to the readout technology the spatial and time resolution is limited. To meet the expanded demands a more comprehensive device is under development. It will be an all-purpose residual gas monitor to cover the wide range of beam currents and transversal particle distributions. Due to the fast profile detection it will operate on primary electrons after residual gas ionization. A magnetic field of 100 mT binds them to the ionization point inside 0.1-mm orbits. The high-resolution mode will be read out by a digital CCD camera with an upstream MCP-phosphor screen assembly. It is planned to read out the fast turn-by-turn mode by an array of 100 photodiodes with a resolution of 1 mm. Every photodiode is equipped with an amplifier-digitizer device providing a frame rate of ˜ 10 MSamples/s.
NASA Astrophysics Data System (ADS)
Limonova, Elena; Tropin, Daniil; Savelyev, Boris; Mamay, Igor; Nikolaev, Dmitry
2018-04-01
In this paper we describe stitching protocol, which allows to obtain high resolution images of long length monochromatic objects with periodic structure. This protocol can be used for long length documents or human-induced objects in satellite images of uninhabitable regions like Arctic regions. The length of such objects can reach notable values, while modern camera sensors have limited resolution and are not able to provide good enough image of the whole object for further processing, e.g. using in OCR system. The idea of the proposed method is to acquire a video stream containing full object in high resolution and use image stitching. We expect the scanned object to have straight boundaries and periodic structure, which allow us to introduce regularization to the stitching problem and adapt algorithm for limited computational power of mobile and embedded CPUs. With the help of detected boundaries and structure we estimate homography between frames and use this information to reduce complexity of stitching. We demonstrate our algorithm on mobile device and show image processing speed of 2 fps on Samsung Exynos 5422 processor
NASA Astrophysics Data System (ADS)
Kang, Jinbum; Jang, Won Seuk; Yoo, Yangmo
2018-02-01
Ultrafast compound Doppler imaging based on plane-wave excitation (UCDI) can be used to evaluate cardiovascular diseases using high frame rates. In particular, it provides a fully quantifiable flow analysis over a large region of interest with high spatio-temporal resolution. However, the pulse-repetition frequency (PRF) in the UCDI method is limited for high-velocity flow imaging since it has a tradeoff between the number of plane-wave angles (N) and acquisition time. In this paper, we present high PRF ultrafast sliding compound Doppler imaging method (HUSDI) to improve quantitative flow analysis. With the HUSDI method, full scanline images (i.e. each tilted plane wave data) in a Doppler frame buffer are consecutively summed using a sliding window to create high-quality ensemble data so that there is no reduction in frame rate and flow sensitivity. In addition, by updating a new compounding set with a certain time difference (i.e. sliding window step size or L), the HUSDI method allows various Doppler PRFs with the same acquisition data to enable a fully qualitative, retrospective flow assessment. To evaluate the performance of the proposed HUSDI method, simulation, in vitro and in vivo studies were conducted under diverse flow circumstances. In the simulation and in vitro studies, the HUSDI method showed improved hemodynamic representations without reducing either temporal resolution or sensitivity compared to the UCDI method. For the quantitative analysis, the root mean squared velocity error (RMSVE) was measured using 9 angles (-12° to 12°) with L of 1-9, and the results were found to be comparable to those of the UCDI method (L = N = 9), i.e. ⩽0.24 cm s-1, for all L values. For the in vivo study, the flow data acquired from a full cardiac cycle of the femoral vessels of a healthy volunteer were analyzed using a PW spectrogram, and arterial and venous flows were successfully assessed with high Doppler PRF (e.g. 5 kHz at L = 4). These results indicate that the proposed HUSDI method can improve flow visualization and quantification with a higher frame rate, PRF and flow sensitivity in cardiovascular imaging.
Kang, Jinbum; Jang, Won Seuk; Yoo, Yangmo
2018-02-09
Ultrafast compound Doppler imaging based on plane-wave excitation (UCDI) can be used to evaluate cardiovascular diseases using high frame rates. In particular, it provides a fully quantifiable flow analysis over a large region of interest with high spatio-temporal resolution. However, the pulse-repetition frequency (PRF) in the UCDI method is limited for high-velocity flow imaging since it has a tradeoff between the number of plane-wave angles (N) and acquisition time. In this paper, we present high PRF ultrafast sliding compound Doppler imaging method (HUSDI) to improve quantitative flow analysis. With the HUSDI method, full scanline images (i.e. each tilted plane wave data) in a Doppler frame buffer are consecutively summed using a sliding window to create high-quality ensemble data so that there is no reduction in frame rate and flow sensitivity. In addition, by updating a new compounding set with a certain time difference (i.e. sliding window step size or L), the HUSDI method allows various Doppler PRFs with the same acquisition data to enable a fully qualitative, retrospective flow assessment. To evaluate the performance of the proposed HUSDI method, simulation, in vitro and in vivo studies were conducted under diverse flow circumstances. In the simulation and in vitro studies, the HUSDI method showed improved hemodynamic representations without reducing either temporal resolution or sensitivity compared to the UCDI method. For the quantitative analysis, the root mean squared velocity error (RMSVE) was measured using 9 angles (-12° to 12°) with L of 1-9, and the results were found to be comparable to those of the UCDI method (L = N = 9), i.e. ⩽0.24 cm s -1 , for all L values. For the in vivo study, the flow data acquired from a full cardiac cycle of the femoral vessels of a healthy volunteer were analyzed using a PW spectrogram, and arterial and venous flows were successfully assessed with high Doppler PRF (e.g. 5 kHz at L = 4). These results indicate that the proposed HUSDI method can improve flow visualization and quantification with a higher frame rate, PRF and flow sensitivity in cardiovascular imaging.
4K Video of Colorful Liquid in Space
2015-10-09
Once again, astronauts on the International Space Station dissolved an effervescent tablet in a floating ball of water, and captured images using a camera capable of recording four times the resolution of normal high-definition cameras. The higher resolution images and higher frame rate videos can reveal more information when used on science investigations, giving researchers a valuable new tool aboard the space station. This footage is one of the first of its kind. The cameras are being evaluated for capturing science data and vehicle operations by engineers at NASA's Marshall Space Flight Center in Huntsville, Alabama.
First Galileo image of asteroid 243 Ida
NASA Technical Reports Server (NTRS)
Chapman, C. R.; Belton, M. J. S.; Veverka, J.; Neukum, G.; Head, J.; Greeley, Ronald; Klaasen, K.; Morrison, D.
1994-01-01
The second spacecraft encounter with an asteroid has yielded an unprecedentedly high resolution portrait of 243 Ida. On 28 Aug. 1993, Galileo obtained an extensive data set on this small member of the Koronis family. Most of the data recorded on the tape recorder will be returned to Earth in spring 1994. A five-frame mosaic of Ida was acquired with good illumination geometry a few minutes before closest approach; it has a resolution of 31 to 38 m/pixel amd was played back during Sept. 1993. Preliminary analyses of this single view of Ida are summarized.
NASA Astrophysics Data System (ADS)
Berthon, Beatrice; Dansette, Pierre-Marc; Tanter, Mickaël; Pernot, Mathieu; Provost, Jean
2017-07-01
Direct imaging of the electrical activation of the heart is crucial to better understand and diagnose diseases linked to arrhythmias. This work presents an ultrafast acoustoelectric imaging (UAI) system for direct and non-invasive ultrafast mapping of propagating current densities using the acoustoelectric effect. Acoustoelectric imaging is based on the acoustoelectric effect, the modulation of the medium’s electrical impedance by a propagating ultrasonic wave. UAI triggers this effect with plane wave emissions to image current densities. An ultrasound research platform was fitted with electrodes connected to high common-mode rejection ratio amplifiers and sampled by up to 128 independent channels. The sequences developed allow for both real-time display of acoustoelectric maps and long ultrafast acquisition with fast off-line processing. The system was evaluated by injecting controlled currents into a saline pool via copper wire electrodes. Sensitivity to low current and low acoustic pressure were measured independently. Contrast and spatial resolution were measured for varying numbers of plane waves and compared to line per line acoustoelectric imaging with focused beams at equivalent peak pressure. Temporal resolution was assessed by measuring time-varying current densities associated with sinusoidal currents. Complex intensity distributions were also imaged in 3D. Electrical current densities were detected for injected currents as low as 0.56 mA. UAI outperformed conventional focused acoustoelectric imaging in terms of contrast and spatial resolution when using 3 and 13 plane waves or more, respectively. Neighboring sinusoidal currents with opposed phases were accurately imaged and separated. Time-varying currents were mapped and their frequency accurately measured for imaging frame rates up to 500 Hz. Finally, a 3D image of a complex intensity distribution was obtained. The results demonstrated the high sensitivity of the UAI system proposed. The plane wave based approach provides a highly flexible trade-off between frame rate, resolution and contrast. In conclusion, the UAI system shows promise for non-invasive, direct and accurate real-time imaging of electrical activation in vivo.
Evaluating the Human Damage of Tsunami at Each Time Frame in Aggregate Units Based on GPS data
NASA Astrophysics Data System (ADS)
Ogawa, Y.; Akiyama, Y.; Kanasugi, H.; Shibasaki, R.; Kaneda, H.
2016-06-01
Assessments of the human damage caused by the tsunami are required in order to consider disaster prevention at such a regional level. Hence, there is an increasing need for the assessments of human damage caused by earthquakes. However, damage assessments in japan currently usually rely on static population distribution data, such as statistical night time population data obtained from national census surveys. Therefore, human damage estimation that take into consideration time frames have not been assessed yet. With these backgrounds, the objectives of this study are: to develop a method for estimating the population distribution of the for each time frame, based on location positioning data observed with mass GPS loggers of mobile phones, to use a evacuation and casualties models for evaluating human damage due to the tsunami, and evaluate each time frame by using the data developed in the first objective, and 3) to discuss the factors which cause the differences in human damage for each time frame. By visualizing the results, we clarified the differences in damage depending on time frame, day and area. As this study enables us to assess damage for any time frame in and high resolution, it will be useful to consider provision for various situations when an earthquake may hit, such as during commuting hours or working hours and week day or holiday.
Seeing tobacco mosaic virus through direct electron detectors
Fromm, Simon A.; Bharat, Tanmay A.M.; Jakobi, Arjen J.; Hagen, Wim J.H.; Sachse, Carsten
2015-01-01
With the introduction of direct electron detectors (DED) to the field of electron cryo-microscopy, a wave of atomic-resolution structures has become available. As the new detectors still require comparative characterization, we have used tobacco mosaic virus (TMV) as a test specimen to study the quality of 3D image reconstructions from data recorded on the two direct electron detector cameras, K2 Summit and Falcon II. Using DED movie frames, we explored related image-processing aspects and compared the performance of micrograph-based and segment-based motion correction approaches. In addition, we investigated the effect of dose deposition on the atomic-resolution structure of TMV and show that radiation damage affects negative carboxyl chains first in a side-chain specific manner. Finally, using 450,000 asymmetric units and limiting the effects of radiation damage, we determined a high-resolution cryo-EM map at 3.35 Å resolution. Here, we provide a comparative case study of highly ordered TMV recorded on different direct electron detectors to establish recording and processing conditions that enable structure determination up to 3.2 Å in resolution using cryo-EM. PMID:25528571
NASA Technical Reports Server (NTRS)
Selzer, Robert H. (Inventor); Hodis, Howard N. (Inventor)
2011-01-01
A standardized acquisition methodology assists operators to accurately replicate high resolution B-mode ultrasound images obtained over several spaced-apart examinations utilizing a split-screen display in which the arterial ultrasound image from an earlier examination is displayed on one side of the screen while a real-time "live" ultrasound image from a current examination is displayed next to the earlier image on the opposite side of the screen. By viewing both images, whether simultaneously or alternately, while manually adjusting the ultrasound transducer, an operator is able to bring into view the real-time image that best matches a selected image from the earlier ultrasound examination. Utilizing this methodology, dynamic material properties of arterial structures, such as IMT and diameter, are measured in a standard region over successive image frames. Each frame of the sequence has its echo edge boundaries automatically determined by using the immediately prior frame's true echo edge coordinates as initial boundary conditions. Computerized echo edge recognition and tracking over multiple successive image frames enhances measurement of arterial diameter and IMT and allows for improved vascular dimension measurements, including vascular stiffness and IMT determinations.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Han, B; Xing, L; Wang, L
Purpose: To systematically investigate an ultra-high spatial-resolution amorphous silicon flat-panel electronic portal imaging device (EPID) for MLC-based full-body robotic radiosurgery geometric and dosimetric quality assurance (QA). Methods: The high frame-rate and ultra-high spatial resolution EPID is an outstanding detector for measuring profiles, MLC-shaped radiosurgery field aperture verification, and small field dosimetry. A Monte Carlo based technique with a robotic linac specific response and calibration is developed to convert a raw EPID-measured image of a radiosurgery field into water-based dose distribution. The technique is applied to measure output factors and profiles for 6MV MLC-defined radiosurgery fields with various sizes ranging frommore » 7.6mm×7.7mm to 100mm×100.1mm and the results are compared with the radiosurgery diode scan measurements in water tank. The EPID measured field sizes and the penumbra regions are analyzed to evaluate the MLC positioning accuracy. Results: For all MLC fields, the EPID measured output factors of MLC-shaped fields are in good agreement with the diode measurements. The mean output difference between the EPID and diode measurement is 0.05±0.87%. The max difference is −1.33% for 7.6mm×7.7mm field. The MLC field size derived from the EPID measurements are in good agreement comparing to the diode scan result. For crossline field sizes, the mean difference is −0.17mm±0.14mm with a maximum of −0.35mm for the 30.8mm×30.8mm field. For inline field sizes, the mean difference is +0.08mm±0.18mm with a maximum of +0.45mm for the 100mm×100.1mm field. The high resolution EPID is able to measure the whole radiation field, without the need to align the detector center perfectly at field center as diode or ion chamber measurement. The setup time is greatly reduced so that the whole process is possible for machine and patient-specific QA. Conclusion: The high spatial-resolution EPID is proved to be an accurate and efficient tool for QA of MLC-equipped robotic radiosurgery system.« less
van Turnhout, J.
2016-01-01
The dielectric spectra of colloidal systems often contain a typical low frequency dispersion, which usually remains unnoticed, because of the presence of strong conduction losses. The KK relations offer a means for converting ε′ into ε″ data. This allows us to calculate conduction free ε″ spectra in which the l.f. dispersion will show up undisturbed. This interconversion can be done on line with a moving frame of logarithmically spaced ε′ data. The coefficients of the conversion frames were obtained by kernel matching and by using symbolic differential operators. Logarithmic derivatives and differences of ε′ and ε″ provide another option for conduction free data analysis. These difference-based functions actually derived from approximations to the distribution function, have the additional advantage of improving the resolution power of dielectric studies. A high resolution is important because of the rich relaxation structure of colloidal suspensions. The development of all-in-1 modeling facilitates the conduction free and high resolution data analysis. This mathematical tool allows the apart-together fitting of multiple data and multiple model functions. It proved also useful to go around the KK conversion altogether. This was achieved by the combined approximating ε′ and ε″ data with a complex rational fractional power function. The all-in-1 minimization turned out to be also highly useful for the dielectric modeling of a suspension with the complex dipolar coefficient. It guarantees a secure correction for the electrode polarization, so that the modeling with the help of the differences ε′ and ε″ can zoom in on the genuine colloidal relaxations. PMID:27242997
ASSESSING ASTROPHYSICAL UNCERTAINTIES IN DIRECT DETECTION WITH GALAXY SIMULATIONS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sloane, Jonathan D.; Buckley, Matthew R.; Brooks, Alyson M.
2016-11-01
We study the local dark matter velocity distribution in simulated Milky Way-mass galaxies, generated at high resolution with both dark matter and baryons. We find that the dark matter in the solar neighborhood is influenced appreciably by the inclusion of baryons, increasing the speed of dark matter particles compared to dark matter-only simulations. The gravitational potential due to the presence of a baryonic disk increases the amount of high velocity dark matter, resulting in velocity distributions that are more similar to the Maxwellian Standard Halo Model than predicted from dark matter-only simulations. Furthermore, the velocity structures present in baryonic simulationsmore » possess a greater diversity than expected from dark matter-only simulations. We show that the impact on the direct detection experiments LUX, DAMA/Libra, and CoGeNT using our simulated velocity distributions, and explore how resolution and halo mass within the Milky Way’s estimated mass range impact the results. A Maxwellian fit to the velocity distribution tends to overpredict the amount of dark matter in the high velocity tail, even with baryons, and thus leads to overly optimistic direct detection bounds on models that are dependent on this region of phase space for an experimental signal. Our work further demonstrates that it is critical to transform simulated velocity distributions to the lab frame of reference, due to the fact that velocity structure in the solar neighborhood appears when baryons are included. There is more velocity structure present when baryons are included than in dark matter-only simulations. Even when baryons are included, the importance of the velocity structure is not as apparent in the Galactic frame of reference as in the Earth frame.« less
Boyde, A; Vesely, P; Gray, C; Jones, S J
1994-01-01
Chick and rat bone-derived cells were mounted in sealed coverslip-covered chambers; individual osteoclasts (but also osteoblasts) were selected and studied at 37 degrees C using three different types of high-speed scanning confocal microscopes: (1) A Noran Tandem Scanning Microscope (TSM) was used with a low light level, cooled CCD camera for image transfer to a Noran TN8502 frame store-based image analysing computer to make time lapse movie sequences using 0.1 s exposure periods, thus losing some of the advantage of the high frame rate of the TSM. Rapid focus adjustment using computer controlled piezo drivers permitted two or more focus planes to be imaged sequentially: thus (with additional light-source shuttering) the reflection confocal image could be alternated with the phase contrast image at a different focus. Individual cells were followed for up to 5 days, suggesting no significant irradiation problem. (2) Exceptional temporal and spatial resolution is available in video rate laser confocal scanning microscopes (VRCSLMs). We used the Noran Odyssey unitary beam VRCSLM with an argon ion laser at 488 nm and acousto-optic deflection (AOD) on the line axis: this instrument is truly and adjustably confocal in the reflection mode. (3) We also used the Lasertec 1LM11 line scan instrument, with an He-Ne laser at 633 nm, and AOD for the frame scan. We discuss the technical problems and merits of the different approaches. The VRCSLMs documented rapid, real-time oscillatory motion: all the methods used show rapid net movement of organelles within bone cells. The interference reflection mode gives particularly strong contrasts in confocal instruments. Phase contrast and other interference methods used in the microscopy of living cells can be used simultaneously in the TSM.
Development of a fast multi-line x-ray CT detector for NDT
NASA Astrophysics Data System (ADS)
Hofmann, T.; Nachtrab, F.; Schlechter, T.; Neubauer, H.; Mühlbauer, J.; Schröpfer, S.; Ernst, J.; Firsching, M.; Schweiger, T.; Oberst, M.; Meyer, A.; Uhlmann, N.
2015-04-01
Typical X-ray detectors for non-destructive testing (NDT) are line detectors or area detectors, like e.g. flat panel detectors. Multi-line detectors are currently only available in medical Computed Tomography (CT) scanners. Compared to flat panel detectors, line and multi-line detectors can achieve much higher frame rates. This allows time-resolved 3D CT scans of an object under investigation. Also, an improved image quality can be achieved due to reduced scattered radiation from object and detector themselves. Another benefit of line and multi-line detectors is that very wide detectors can be assembled easily, while flat panel detectors are usually limited to an imaging field with a size of approx. 40 × 40 cm2 at maximum. The big disadvantage of line detectors is the limited number of object slices that can be scanned simultaneously. This leads to long scan times for large objects. Volume scans with a multi-line detector are much faster, but with almost similar image quality. Due to the promising properties of multi-line detectors their application outside of medical CT would also be very interesting for NDT. However, medical CT multi-line detectors are optimized for the scanning of human bodies. Many non-medical applications require higher spatial resolutions and/or higher X-ray energies. For those non-medical applications we are developing a fast multi-line X-ray detector.In the scope of this work, we present the current state of the development of the novel detector, which includes several outstanding properties like an adjustable curved design for variable focus-detector-distances, conserving nearly uniform perpendicular irradiation over the entire detector width. Basis of the detector is a specifically designed, radiation hard CMOS imaging sensor with a pixel pitch of 200 μ m. Each pixel has an automatic in-pixel gain adjustment, which allows for both: a very high sensitivity and a wide dynamic range. The final detector is planned to have 256 lines of pixels. By using a modular assembly of the detector, the width can be chosen as multiples of 512 pixels. With a frame rate of up to 300 frames/s (full resolution) or 1200 frame/s (analog binning to 400 μ m pixel pitch) time-resolved 3D CT applications become possible. Two versions of the detector are in development, one with a high resolution scintillator and one with a thick, structured and very efficient scintillator (pitch 400 μ m). This way the detector can even work with X-ray energies up to 450 kVp.
Giewekemeyer, Klaus; Philipp, Hugh T.; Wilke, Robin N.; Aquila, Andrew; Osterhoff, Markus; Tate, Mark W.; Shanks, Katherine S.; Zozulya, Alexey V.; Salditt, Tim; Gruner, Sol M.; Mancuso, Adrian P.
2014-01-01
Coherent (X-ray) diffractive imaging (CDI) is an increasingly popular form of X-ray microscopy, mainly due to its potential to produce high-resolution images and the lack of an objective lens between the sample and its corresponding imaging detector. One challenge, however, is that very high dynamic range diffraction data must be collected to produce both quantitative and high-resolution images. In this work, hard X-ray ptychographic coherent diffractive imaging has been performed at the P10 beamline of the PETRA III synchrotron to demonstrate the potential of a very wide dynamic range imaging X-ray detector (the Mixed-Mode Pixel Array Detector, or MM-PAD). The detector is capable of single photon detection, detecting fluxes exceeding 1 × 108 8-keV photons pixel−1 s−1, and framing at 1 kHz. A ptychographic reconstruction was performed using a peak focal intensity on the order of 1 × 1010 photons µm−2 s−1 within an area of approximately 325 nm × 603 nm. This was done without need of a beam stop and with a very modest attenuation, while ‘still’ images of the empty beam far-field intensity were recorded without any attenuation. The treatment of the detector frames and CDI methodology for reconstruction of non-sensitive detector regions, partially also extending the active detector area, are described. PMID:25178008
Giewekemeyer, Klaus; Philipp, Hugh T; Wilke, Robin N; Aquila, Andrew; Osterhoff, Markus; Tate, Mark W; Shanks, Katherine S; Zozulya, Alexey V; Salditt, Tim; Gruner, Sol M; Mancuso, Adrian P
2014-09-01
Coherent (X-ray) diffractive imaging (CDI) is an increasingly popular form of X-ray microscopy, mainly due to its potential to produce high-resolution images and the lack of an objective lens between the sample and its corresponding imaging detector. One challenge, however, is that very high dynamic range diffraction data must be collected to produce both quantitative and high-resolution images. In this work, hard X-ray ptychographic coherent diffractive imaging has been performed at the P10 beamline of the PETRA III synchrotron to demonstrate the potential of a very wide dynamic range imaging X-ray detector (the Mixed-Mode Pixel Array Detector, or MM-PAD). The detector is capable of single photon detection, detecting fluxes exceeding 1 × 10(8) 8-keV photons pixel(-1) s(-1), and framing at 1 kHz. A ptychographic reconstruction was performed using a peak focal intensity on the order of 1 × 10(10) photons µm(-2) s(-1) within an area of approximately 325 nm × 603 nm. This was done without need of a beam stop and with a very modest attenuation, while `still' images of the empty beam far-field intensity were recorded without any attenuation. The treatment of the detector frames and CDI methodology for reconstruction of non-sensitive detector regions, partially also extending the active detector area, are described.
A metrology system for a high resolution cavity beam position monitor system
NASA Astrophysics Data System (ADS)
Walston, Sean; Boogert, Stewart; Chung, Carl; Fitsos, Pete; Frisch, Joe; Gronberg, Jeff; Hayano, Hitoshi; Hinton, Shantell; Honda, Yosuke; Khainovski, Oleg; Kolomensky, Yury; Loscutoff, Peter; Lyapin, Alexey; Malton, Stephen; May, Justin; McCormick, Douglas; Meller, Robert; Miller, David; Orimoto, Toyoko; Ross, Marc; Slater, Mark; Smith, Steve; Smith, Tonee; Terunuma, Nobuhiro; Thomson, Mark; Urakawa, Junji; Vogel, Vladimir; Ward, David; White, Glen
2013-11-01
International Linear Collider (ILC) interaction region beam sizes and component position stability requirements will likely be as small as a few nanometers. It is important to the ILC design effort to demonstrate that these tolerances can be achieved-ideally using a beam-based stability measurement. We developed a high resolution RF cavity Beam Position Monitor (BPM) system. A triplet of these BPMs, installed in the extraction line of the KEK Accelerator Test Facility (ATF) and tested with its ultra-low emittance beam, achieved a position measurement resolution of 15 nm. A metrology system for the three BPMs was subsequently installed. This system employed optical encoders to measure each BPM's position and orientation relative to a zero-coefficient of thermal expansion carbon fiber frame. We have demonstrated that the three BPMs behave as a rigid-body at the level of less than 5 nm.
Waseda, Katsuhisa; Ako, Junya; Yamasaki, Masao; Koizumi, Tomomi; Sakurai, Ryota; Hongo, Yoichiro; Koo, Bon-Kwon; Ormiston, John; Worthley, Stephen G; Whitbourn, Robert J; Walters, Darren L; Meredith, Ian T; Fitzgerald, Peter J; Honda, Yasuhiro
2011-06-01
Polymer formulation may affect the efficacy of drug-eluting stents. Resolute, Endeavor, and ZoMaxx are zotarolimus-eluting stents with different stent platforms and different polymer coatings and have been tested in clinical trials. The aim of this analysis was to compare the efficacy of zotarolimus-eluting stents with different polymers. Data were obtained from the first-in man trial or first randomized trials of each stent, The Clinical RESpOnse EvaLUation of the MedTronic Endeavor CR ABT-578 Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions (RESOLUTE), Randomized Controlled Trial to Evaluate the Safety and Efficacy of the Medtronic AVE ABT-578 Eluting Driver Coronary Stent in De Novo Native Coronary Artery Lesions (ENDEAVOR II), and ZoMaxx I trials. Follow-up intravascular ultrasound analyses (8 to 9 months of follow-up) were possible in 353 patients (Resolute: 88, Endeavor: 98, ZoMaxx: 82, Driver: 85). Volume index (volume/stent length) was obtained for vessel, stent, lumen, peristent plaque, and neointima. Cross-sectional narrowing was defined as neointimal area divided by stent area (%). Neointima-free frame ratio was calculated as the number of frames without intravascular ultrasound-detectable neointima divided by the total number of frames within the stent. At baseline, vessel, lumen, and peristent plaque volume index were not significantly different among the 4 stent groups. At follow-up, percent neointimal obstruction was significantly lower in Resolute compared with Endeavor, ZoMaxx, and Driver (Resolute: 3.7±4.0, Endeavor: 17.5±10.1, ZoMaxx: 14.6±8.1, Driver: 29.4±17.2%; P<0.001). Greater maximum cross-sectional narrowing and higher neointima-free frame ratio, suggesting less neointimal coverage, were observed in Resolute compared with other stent groups. Multiple regression analysis confirmed that the biodurable polymer used in Resolute independently correlated with neointimal suppression among 3 zotarolimus-eluting stents. The different polymer formulations significantly affect the relative amount of neointima for zotarolimus-eluting stents. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00248079.
Next generation miniature simultaneous multi-hyperspectral imaging systems
NASA Astrophysics Data System (ADS)
Hinnrichs, Michele; Gupta, Neelam
2014-03-01
The concept for a hyperspectral imaging system using a Fabry-Perot tunable filter (FPTF) array that is fabricated using "miniature optical electrical mechanical system" (MOEMS) technology. [1] Using an array of FPTF as an approach to hyperspectral imaging relaxes wavelength tuning requirements considerably because of the reduced portion of the spectrum that is covered by each element in the array. In this paper, Pacific Advanced Technology and ARL present the results of a concept design and performed analysis of a MOEMS based tunable Fabry-Perot array (FPTF) to perform simultaneous multispectral and hyperspectral imaging with relatively high spatial resolution. The concept design was developed with support of an Army SBIR Phase I program The Fabry-Perot tunable MOEMS filter array was combined with a miniature optics array and a focal plane array of 1024 x 1024 pixels to produce 16 colors every frame of the camera. Each color image has a spatial resolution of 256 x 256 pixels with an IFOV of 1.7 mrads and FOV of 25 degrees. The spectral images are collected simultaneously allowing high resolution spectral-spatial-temporal information in each frame of the camera, thus enabling the implementation of spectral-temporal-spatial algorithms in real-time to provide high sensitivity for the detection of weak signals in a high clutter background environment with low sensitivity to camera motion. The challenge in the design was the independent actuation of each Fabry Perot element in the array allowing for individual tuning. An additional challenge was the need to maximize the fill factor to improve the spatial coverage with minimal dead space. This paper will only address the concept design and analysis of the Fabry-Perot tunable filter array. A previous paper presented at SPIE DSS in 2012 explained the design of the optical array.
Ultrafast Ultrasound Imaging of Ocular Anatomy and Blood Flow
Urs, Raksha; Ketterling, Jeffrey A.; Silverman, Ronald H.
2016-01-01
Purpose Ophthalmic ultrasound imaging is currently performed with mechanically scanned single-element probes. These probes have limited capabilities overall and lack the ability to image blood flow. Linear-array systems are able to detect blood flow, but these systems exceed ophthalmic acoustic intensity safety guidelines. Our aim was to implement and evaluate a new linear-array–based technology, compound coherent plane-wave ultrasound, which offers ultrafast imaging and depiction of blood flow at safe acoustic intensity levels. Methods We compared acoustic intensity generated by a 128-element, 18-MHz linear array operated in conventionally focused and plane-wave modes and characterized signal-to-noise ratio (SNR) and lateral resolution. We developed plane-wave B-mode, real-time color-flow, and high-resolution depiction of slow flow in postprocessed data collected continuously at a rate of 20,000 frames/s. We acquired in vivo images of the posterior pole of the eye by compounding plane-wave images acquired over ±10° and produced images depicting orbital and choroidal blood flow. Results With the array operated conventionally, Doppler modes exceeded Food and Drug Administration safety guidelines, but plane-wave modalities were well within guidelines. Plane-wave data allowed generation of high-quality compound B-mode images, with SNR increasing with the number of compounded frames. Real-time color-flow Doppler readily visualized orbital blood flow. Postprocessing of continuously acquired data blocks of 1.6-second duration allowed high-resolution depiction of orbital and choroidal flow over the cardiac cycle. Conclusions Newly developed high-frequency linear arrays in combination with plane-wave techniques present opportunities for the evaluation of ocular anatomy and blood flow, as well as visualization and analysis of other transient phenomena such as vessel wall motion over the cardiac cycle and saccade-induced vitreous motion. PMID:27428169
Pushing x-ray photon correlation spectroscopy beyond the continuous frame rate limit
Dufresne, Eric M.; Narayanan, Suresh; Sandy, Alec R.; ...
2016-01-06
We demonstrate delayed-frame X-ray Photon Correlation Spectroscopy with 120 microsecond time resolution, limited only by sample scattering rates, with a prototype Pixel-array detector capable of taking two image frames separated by 153 ns or less. Although the overall frame rate is currently limited to about 4 frame pairs per second, we easily measured millisecond correlation functions. In conclusion, this technology, coupled to the use of brighter synchrotrons such as Petra III or the NSLS-II should enable X-ray Photon Correlation Spectroscopy on microsecond time scales on a wider variety of materials.
Fast Solar Polarimeter: Prototype Characterization and First Results
NASA Astrophysics Data System (ADS)
Iglesias, F. A.; Feller, A.; Krishnappa, N.; Solanki, S. K.
2016-04-01
Due to the differential and non-simultaneous nature of polarization measurements, seeing induced crosstalk (SIC) and seeing limited spatial resolution can easily counterbalance the benefits of solar imaging polarimetry from the ground. The development of instrumental techniques to treat these issues is necessary to fully exploit the next generation of large-aperture solar facilities, and maintain ground-based data at a competitive level with respect to its space-based counterpart. In particular, considering that many open questions in modern solar physics demand data with challenging specifications of resolution and polarimetric sensitivity that can only be achieved with large telescope apertures (Stenflo 1999). Even if state-of-the-art adaptive optics systems greatly improve image quality, their limited correction —due to finite bandwidth, mode number and seeing anisoplanat- ism— produces large residual values of SIC (Krishnappa & Feller 2012). Dual beam polarimeters are commonly used to reduce SIC between the intensity and polarization signals, however, they cannot compensate for the SIC introduced between circular and linear polarization, which can be relevant for high-precision polarimetry. It is known that fast modulation effectively reduces SIC, but the demodulation of the corresponding intensity signals imposes hard requirements on the frame rate of the associated cameras. One way to avoid a fast sensor, is to decouple the camera readout from the intensity demodulation step. This concept is the cornerstone of the very successful Zurich Imaging Polarimeter (ZIMPOL). Even though the ZIMPOL solution allows the detection of very faint signals (˜10-5), its design is not suitable for high-spatial-resolution applications. We are developing a polarimeter that focuses on both spatial resolution (<0.5 arcsec) and polarimetric sensitivity (10-4). The prototype of this Fast Solar Polarimeter (FSP, see Feller et al. 2014), employs a high frame-rate (400 fps), low-noise (<4 e- RMS), pnCCD camera (Hartmann et al. 2006) that is read in synchronization with a polarization modulator based on ferroelectric liquid crystals. The modulator package is similar to the SOLIS (Keller et al. 2003) design and optimized to have an achromatic total polarimetric efficiency above 80 % in the 400-700 nm wavelength range. The fast modulation frequency of FSP, yielding up to 100 full-Stokes measurements per second, and high duty cycle (>95%), have the double benefit of reducing seeing induced artifacts and improving the final spatial resolution by providing an optimal regime for the application of post-facto image reconstruction techniques. In this poster we describe the FSP prototype, including the characterization results, a technique to correct image smearing due to the sensor frame transfer (Iglesias et al. 2015) and some of the first measurements obtained with the 68-cm Vacuum Tower Telescope located at the Observatorio del Teide, Spain.
Robust graphene membranes in a silicon carbide frame.
Waldmann, Daniel; Butz, Benjamin; Bauer, Sebastian; Englert, Jan M; Jobst, Johannes; Ullmann, Konrad; Fromm, Felix; Ammon, Maximilian; Enzelberger, Michael; Hirsch, Andreas; Maier, Sabine; Schmuki, Patrik; Seyller, Thomas; Spiecker, Erdmann; Weber, Heiko B
2013-05-28
We present a fabrication process for freely suspended membranes consisting of bi- and trilayer graphene grown on silicon carbide. The procedure, involving photoelectrochemical etching, enables the simultaneous fabrication of hundreds of arbitrarily shaped membranes with an area up to 500 μm(2) and a yield of around 90%. Micro-Raman and atomic force microscopy measurements confirm that the graphene layer withstands the electrochemical etching and show that the membranes are virtually unstrained. The process delivers membranes with a cleanliness suited for high-resolution transmission electron microscopy (HRTEM) at atomic scale. The membrane, and its frame, is very robust with respect to thermal cycling above 1000 °C as well as harsh acidic or alkaline treatment.
Small-Size High-Current Generators for X-Ray Backlighting
NASA Astrophysics Data System (ADS)
Chaikovsky, S. A.; Artyomov, A. P.; Zharova, N. V.; Zhigalin, A. S.; Lavrinovich, I. V.; Oreshkin, V. I.; Ratakhin, N. A.; Rousskikh, A. G.; Fedunin, A. V.; Fedushchak, V. F.; Erfort, A. A.
2017-12-01
The paper deals with the soft X-ray backlighting based on the X-pinch as a powerful tool for physical studies of fast processes. Proposed are the unique small-size pulsed power generators operating as a low-inductance capacitor bank. These pulse generators provide the X-pinch-based soft X-ray source (hν = 1-10 keV) of micron size at 2-3 ns pulse duration. The small size and weight of pulse generators allow them to be transported to any laboratory for conducting X-ray backlighting of test objects with micron space resolution and nanosecond exposure time. These generators also allow creating synchronized multi-frame radiographic complexes with frame delay variation in a broad range.
Logic design and implementation of FPGA for a high frame rate ultrasound imaging system
NASA Astrophysics Data System (ADS)
Liu, Anjun; Wang, Jing; Lu, Jian-Yu
2002-05-01
Recently, a method has been developed for high frame rate medical imaging [Jian-yu Lu, ``2D and 3D high frame rate imaging with limited diffraction beams,'' IEEE Trans. Ultrason. Ferroelectr. Freq. Control 44(4), 839-856 (1997)]. To realize this method, a complicated system [multiple-channel simultaneous data acquisition, large memory in each channel for storing up to 16 seconds of data at 40 MHz and 12-bit resolution, time-variable-gain (TGC) control, Doppler imaging, harmonic imaging, as well as coded transmissions] is designed. Due to the complexity of the system, field programmable gate array (FPGA) (Xilinx Spartn II) is used. In this presentation, the design and implementation of the FPGA for the system will be reported. This includes the synchronous dynamic random access memory (SDRAM) controller and other system controllers, time sharing for auto-refresh of SDRAMs to reduce peak power, transmission and imaging modality selections, ECG data acquisition and synchronization, 160 MHz delay locked loop (DLL) for accurate timing, and data transfer via either a parallel port or a PCI bus for post image processing. [Work supported in part by Grant 5RO1 HL60301 from NIH.
Hu, D; Sarder, P; Ronhovde, P; Orthaus, S; Achilefu, S; Nussinov, Z
2014-01-01
Inspired by a multiresolution community detection based network segmentation method, we suggest an automatic method for segmenting fluorescence lifetime (FLT) imaging microscopy (FLIM) images of cells in a first pilot investigation on two selected images. The image processing problem is framed as identifying segments with respective average FLTs against the background in FLIM images. The proposed method segments a FLIM image for a given resolution of the network defined using image pixels as the nodes and similarity between the FLTs of the pixels as the edges. In the resulting segmentation, low network resolution leads to larger segments, and high network resolution leads to smaller segments. Furthermore, using the proposed method, the mean-square error in estimating the FLT segments in a FLIM image was found to consistently decrease with increasing resolution of the corresponding network. The multiresolution community detection method appeared to perform better than a popular spectral clustering-based method in performing FLIM image segmentation. At high resolution, the spectral segmentation method introduced noisy segments in its output, and it was unable to achieve a consistent decrease in mean-square error with increasing resolution. © 2013 The Authors Journal of Microscopy © 2013 Royal Microscopical Society.
Novel ultrasonic real-time scanner featuring servo controlled transducers displaying a sector image.
Matzuk, T; Skolnick, M L
1978-07-01
This paper describes a new real-time servo controlled sector scanner that produces high resolution images and has functionally programmable features similar to phased array systems, but possesses the simplicity of design and low cost best achievable in a mechanical sector scanner. The unique feature is the transducer head which contains a single moving part--the transducer--enclosed within a light-weight, hand held, and vibration free case. The frame rate, sector width, stop action angle, are all operator programmable. The frame rate can be varied from 12 to 30 frames s-1 and the sector width from 0 degrees to 60 degrees. Conversion from sector to time motion (T/M) modes are instant and two options are available, a freeze position high density T/M and a low density T/M obtainable simultaneously during sector visualization. Unusual electronic features are: automatic gain control, electronic recording of images on video tape in rf format, and ability to post-process images during video playback to extract T/M display and to change time gain control (tgc) and image size.
1989-08-25
P-34764 Voyager 2 obtained this high resolution color image of Neptune's large satellite Triton during its close flyby. Approximately a dozen individual images were combined to produce this comprehensive view of the Neptune-facing hemisphere of Triton. Fine detail is provided by high resolution, clear-filter images, with color information added from lower resolution frames. The large south polar cap at the bottom of the image is highly refective and slightly pink in color , and may consist of a slowly evaporating layer of nitrogen ice deposited during the previous winter. From the ragged edge of the polar cap northward the satellite's face is generously darker and redder in color. This coloring may be produced by the action of ultraviolet light and magnetospheric radiation upon methane in the atmosphere and surface. Running across this darker region , approximately parallel to the edge of the polar cap, is a band of brighter white material that is almost bluish in color. The underlying topography in this bright band is similiar, however to that in the darker, redder regions surrounding it.
Design of a real-time system of moving ship tracking on-board based on FPGA in remote sensing images
NASA Astrophysics Data System (ADS)
Yang, Tie-jun; Zhang, Shen; Zhou, Guo-qing; Jiang, Chuan-xian
2015-12-01
With the broad attention of countries in the areas of sea transportation and trade safety, the requirements of efficiency and accuracy of moving ship tracking are becoming higher. Therefore, a systematic design of moving ship tracking onboard based on FPGA is proposed, which uses the Adaptive Inter Frame Difference (AIFD) method to track a ship with different speed. For the Frame Difference method (FD) is simple but the amount of computation is very large, it is suitable for the use of FPGA to implement in parallel. But Frame Intervals (FIs) of the traditional FD method are fixed, and in remote sensing images, a ship looks very small (depicted by only dozens of pixels) and moves slowly. By applying invariant FIs, the accuracy of FD for moving ship tracking is not satisfactory and the calculation is highly redundant. So we use the adaptation of FD based on adaptive extraction of key frames for moving ship tracking. A FPGA development board of Xilinx Kintex-7 series is used for simulation. The experiments show that compared with the traditional FD method, the proposed one can achieve higher accuracy of moving ship tracking, and can meet the requirement of real-time tracking in high image resolution.
Concept for the fast modulation of light in amplitude and phase using analog tilt-mirror arrays
NASA Astrophysics Data System (ADS)
Roth, Matthias; Heber, Jörg; Janschek, Klaus
2017-02-01
The full complex, spatial modulation of light at high frame rates is essential for a variety of applications. In particular, emerging techniques applied to scattering media, such as Digital Optical Phase Conjugation and Wavefront Shaping, request challenging performance parameters. They refer to imaging tasks inside biological media, whose characteristics concerning the transmission and reflection of scattered light may change over time within milliseconds. Thus, these methods call for frame rates in the kilohertz range. Existing solutions typically over frame rate capabilities below 100 Hz, since they rely on liquid crystal spatial light modulators (SLMs). We propose a diffractive MEMS optical system for this application range. It relies on an analog, tilt-type micro mirror array (MMA) based on an established SLM technology, where the standard application is grayscale amplitude control. The new MMA system design allows the phase manipulation at high-speed as well. The article studies properties of the appropriate optical setup by simulating the propagation of the light. Relevant test patterns and sensitivity parameters of the system will be analyzed. Our results illustrate the main opportunities of the concept with particular focus on the tilt mirror technology. They indicate a promising path to realize the complex light modulation at frame rates above 1 kHz and resolutions well beyond 10,000 complex pixels.
Adaptive foveated single-pixel imaging with dynamic supersampling
Phillips, David B.; Sun, Ming-Jie; Taylor, Jonathan M.; Edgar, Matthew P.; Barnett, Stephen M.; Gibson, Graham M.; Padgett, Miles J.
2017-01-01
In contrast to conventional multipixel cameras, single-pixel cameras capture images using a single detector that measures the correlations between the scene and a set of patterns. However, these systems typically exhibit low frame rates, because to fully sample a scene in this way requires at least the same number of correlation measurements as the number of pixels in the reconstructed image. To mitigate this, a range of compressive sensing techniques have been developed which use a priori knowledge to reconstruct images from an undersampled measurement set. Here, we take a different approach and adopt a strategy inspired by the foveated vision found in the animal kingdom—a framework that exploits the spatiotemporal redundancy of many dynamic scenes. In our system, a high-resolution foveal region tracks motion within the scene, yet unlike a simple zoom, every frame delivers new spatial information from across the entire field of view. This strategy rapidly records the detail of quickly changing features in the scene while simultaneously accumulating detail of more slowly evolving regions over several consecutive frames. This architecture provides video streams in which both the resolution and exposure time spatially vary and adapt dynamically in response to the evolution of the scene. The degree of local frame rate enhancement is scene-dependent, but here, we demonstrate a factor of 4, thereby helping to mitigate one of the main drawbacks of single-pixel imaging techniques. The methods described here complement existing compressive sensing approaches and may be applied to enhance computational imagers that rely on sequential correlation measurements. PMID:28439538
Development of a Large Field of View Shadowgraph System for a 16 Ft. Transonic Wind Tunnel
NASA Technical Reports Server (NTRS)
Talley, Michael A.; Jones, Stephen B.; Goodman, Wesley L.
2000-01-01
A large field of view shadowgraph flow visualization system for the Langley 16 ft. Transonic Tunnel (16 ft.TT) has been developed to provide fast, low cost, aerodynamic design concept evaluation capability to support the development of the next generation of commercial and military aircraft and space launch vehicles. Key features of the 16 ft. TT shadowgraph system are: (1) high resolution (1280 X 1024) digital snap shots and sequences; (2) video recording of shadowgraph at 30 frames per second; (3) pan, tilt, & zoom to find and observe flow features; (4) one microsecond flash for freeze frame images; (5) large field of view approximately 12 X 6 ft; and (6) a low maintenance, high signal/noise ratio, retro-reflective screen to allow shadowgraph imaging while test section lights are on.
Agarwal, Krishna; Macháň, Radek; Prasad, Dilip K
2018-03-21
Localization microscopy and multiple signal classification algorithm use temporal stack of image frames of sparse emissions from fluorophores to provide super-resolution images. Localization microscopy localizes emissions in each image independently and later collates the localizations in all the frames, giving same weight to each frame irrespective of its signal-to-noise ratio. This results in a bias towards frames with low signal-to-noise ratio and causes cluttered background in the super-resolved image. User-defined heuristic computational filters are employed to remove a set of localizations in an attempt to overcome this bias. Multiple signal classification performs eigen-decomposition of the entire stack, irrespective of the relative signal-to-noise ratios of the frames, and uses a threshold to classify eigenimages into signal and null subspaces. This results in under-representation of frames with low signal-to-noise ratio in the signal space and over-representation in the null space. Thus, multiple signal classification algorithms is biased against frames with low signal-to-noise ratio resulting into suppression of the corresponding fluorophores. This paper presents techniques to automatically debias localization microscopy and multiple signal classification algorithm of these biases without compromising their resolution and without employing heuristics, user-defined criteria. The effect of debiasing is demonstrated through five datasets of invitro and fixed cell samples.
Analysis of the Effect of UTI-UTC to High Precision Orbit
NASA Astrophysics Data System (ADS)
Shin, Dongseok; Kwak, Sunghee; Kim, Tag-Gon
1999-12-01
As the spatial resolution of remote sensing satellites becomes higher, very accurate determination of the position of a LEO (Low Earth Orbit) satellite is demanding more than ever. Non-symmetric Earth gravity is the major perturbation force to LEO satellites. Since the orbit propagation is performed in the celestial frame while Earth gravity is defined in the terrestrial frame, it is required to convert the coordinates of the satellite from one to the other accurately. Unless the coordinate conversion between the two frames is performed accurately the orbit propagation calculates incorrect Earth gravitational force at a specific time instant, and hence, causes errors in orbit prediction. The coordinate conversion between the two frames involves precession, nutation, Earth rotation and polar motion. Among these factors, unpredictability and uncertainty of Earth rotation, called UTI-UTC, is the largest error source. In this paper, the effect of UTI-UTC on the accuracy of the LEO propagation is introduced, tested and analzed. Considering the maximum unpredictability of UTI-UTC, 0.9 seconds, the meaningful order of non-spherical Earth harmonic functions is derived.
Data management and digital delivery of analog data
Miller, W.A.; Longhenry, Ryan; Smith, T.
2008-01-01
The U.S. Geological Survey's (USGS) data archive at the Earth Resources Observation and Science (EROS) Center is a comprehensive and impartial record of the Earth's changing land surface. USGS/EROS has been archiving and preserving land remote sensing data for over 35 years. This remote sensing archive continues to grow as aircraft and satellites acquire more imagery. As a world leader in preserving data, USGS/EROS has a reputation as a technological innovator in solving challenges and ensuring that access to these collections is available. Other agencies also call on the USGS to consider their collections for long-term archive support. To improve access to the USGS film archive, each frame on every roll of film is being digitized by automated high performance digital camera systems. The system robotically captures a digital image from each film frame for the creation of browse and medium resolution image files. Single frame metadata records are also created to improve access that otherwise involves interpreting flight indexes. USGS/EROS is responsible for over 8.6 million frames of aerial photographs and 27.7 million satellite images.
In-duct identification of a rotating sound source with high spatial resolution
NASA Astrophysics Data System (ADS)
Heo, Yong-Ho; Ih, Jeong-Guon; Bodén, Hans
2015-11-01
To understand and reduce the flow noise generation from in-duct fluid machines, it is necessary to identify the acoustic source characteristics precisely. In this work, a source identification technique, which can identify the strengths and positions of the major sound radiators in the source plane, is studied for an in-duct rotating source. A linear acoustic theory including the effects of evanescent modes and source rotation is formulated based on the modal summation method, which is the underlying theory for the inverse source reconstruction. A validation experiment is conducted on a duct system excited by a loudspeaker in static and rotating conditions, with two different speeds, in the absence of flow. Due to the source rotation, the measured pressure spectra reveal the Doppler effect, and the amount of frequency shift corresponds to the multiplication of the circumferential mode order and the rotation speed. Amplitudes of participating modes are estimated at the shifted frequencies in the stationary reference frame, and the modal amplitude set including the effect of source rotation is collected to investigate the source behavior in the rotating reference frame. By using the estimated modal amplitudes, the near-field pressure is re-calculated and compared with the measured pressure. The obtained maximum relative error is about -25 and -10 dB for rotation speeds at 300 and 600 rev/min, respectively. The spatial distribution of acoustic source parameters is restored from the estimated modal amplitude set. The result clearly shows that the position and magnitude of the main sound source can be identified with high spatial resolution in the rotating reference frame.
Investigation of kinematic features for dismount detection and tracking
NASA Astrophysics Data System (ADS)
Narayanaswami, Ranga; Tyurina, Anastasia; Diel, David; Mehra, Raman K.; Chinn, Janice M.
2012-05-01
With recent changes in threats and methods of warfighting and the use of unmanned aircrafts, ISR (Intelligence, Surveillance and Reconnaissance) activities have become critical to the military's efforts to maintain situational awareness and neutralize the enemy's activities. The identification and tracking of dismounts from surveillance video is an important step in this direction. Our approach combines advanced ultra fast registration techniques to identify moving objects with a classification algorithm based on both static and kinematic features of the objects. Our objective was to push the acceptable resolution beyond the capability of industry standard feature extraction methods such as SIFT (Scale Invariant Feature Transform) based features and inspired by it, SURF (Speeded-Up Robust Feature). Both of these methods utilize single frame images. We exploited the temporal component of the video signal to develop kinematic features. Of particular interest were the easily distinguishable frequencies characteristic of bipedal human versus quadrupedal animal motion. We examine limits of performance, frame rates and resolution required for human, animal and vehicles discrimination. A few seconds of video signal with the acceptable frame rate allow us to lower resolution requirements for individual frames as much as by a factor of five, which translates into the corresponding increase of the acceptable standoff distance between the sensor and the object of interest.
Geomorphological Mapping of Sputnik Planum and Surrounding Terrain on Pluto
NASA Astrophysics Data System (ADS)
White, O. L.; Stern, S. A.; Weaver, H. A., Jr.; Olkin, C.; Ennico Smith, K.; Young, L. A.; Moore, J. M.; Cheng, A. F.
2015-12-01
The New Horizons flyby of Pluto in July 2015 has provided the first few close-up images of the Kuiper belt object, which reveal it to have a highly diverse range of terrains, implying a complex geological history. The highest resolution images that have yet been returned are seven lossy 400 m/pixel frames that cover the majority of the prominent Plutonian feature informally named Sputnik Planum (all feature names are currently informal), and its surroundings. This resolution is sufficient to allow detailed geomorphological mapping of this area to commence. Lossless versions of all 15 frames that make up the mosaic will be returned in September 2015, and the map presented at AGU will incorporate the total area covered by these frames. Sputnik Planum, with an area of ~650,000 km2, is notable for its smooth appearance and apparent total lack of impact craters at 400 m/pixel resolution. The Planum actually displays a wide variety of textures across its expanse, which includes smooth and pitted plains to the south, polygonal terrain at its center (the polygons can reach tens of kilometers in size and are bounded by troughs that sometimes feature central ridges), and, to the north, darker polygonal terrain displaying patterns indicative of glacial flow. Within these plains there exist several well-defined outcrops of a mottled, light/dark unit that reach from several to tens of kilometers across. Separating Sputnik Planum from the dark, cratered equatorial terrain of Cthulhu Regio on its south-western margin is a unit of chaotically arranged mountains; similar mountainous units exist on the south and western margins. The northern margin is bounded by rugged, hilly, cratered terrain into which ice of Sputnik Planum appears to be intruding in places. Terrain of similar relief exists to the east, but is much brighter than that to the north. The southernmost extent of the mosaic features a unit of rough, undulating terrain that displays very few impact craters at 400 m/pixel resolution.
Time stamping of single optical photons with 10 ns resolution
NASA Astrophysics Data System (ADS)
Chakaberia, Irakli; Cotlet, Mircea; Fisher-Levine, Merlin; Hodges, Diedra R.; Nguyen, Jayke; Nomerotski, Andrei
2017-05-01
High spatial and temporal resolution are key features for many modern applications, e.g. mass spectrometry, probing the structure of materials via neutron scattering, studying molecular structure, etc.1-5 Fast imaging also provides the capability of coincidence detection, and the further addition of sensitivity to single optical photons with the capability of timestamping them further broadens the field of potential applications. Photon counting is already widely used in X-ray imaging,6 where the high energy of the photons makes their detection easier. TimepixCam is a novel optical imager,7 which achieves high spatial resolution using an array of 256×256 55 μm × 55μm pixels which have individually controlled functionality. It is based on a thin-entrance-window silicon sensor, bump-bonded to a Timepix ASIC.8 TimepixCam provides high quantum efficiency in the optical wavelength range (400-1000 nm). We perform the timestamping of single photons with a time resolution of 20 ns, by coupling TimepixCam to a fast image-intensifier with a P47 phosphor screen. The fast emission time of the P479 allows us to preserve good time resolution while maintaining the capability to focus the optical output of the intensifier onto the 256×256 pixel Timepix sensor area. We demonstrate the capability of the (TimepixCam + image intensifier) setup to provide high-resolution single-photon timestamping, with an effective frame rate of 50 MHz.
NASA Astrophysics Data System (ADS)
Kendrick, Stephen E.; Harwit, Alex; Kaplan, Michael; Smythe, William D.
2007-09-01
An MWIR TDI (Time Delay and Integration) Imager and Spectrometer (MTIS) instrument for characterizing from orbit the moons of Jupiter and Saturn is proposed. Novel to this instrument is the planned implementation of a digital TDI detector array and an innovative imaging/spectroscopic architecture. Digital TDI enables a higher SNR for high spatial resolution surface mapping of Titan and Enceladus and for improved spectral discrimination and resolution at Europa. The MTIS imaging/spectroscopic architecture combines a high spatial resolution coarse wavelength resolution imaging spectrometer with a hyperspectral sensor to spectrally decompose a portion of the data adjacent to the data sampled in the imaging spectrometer. The MTIS instrument thus maps with high spatial resolution a planetary object while spectrally decomposing enough of the data that identification of the constituent materials is highly likely. Additionally, digital TDI systems have the ability to enable the rejection of radiation induced spikes in high radiation environments (Europa) and the ability to image in low light levels (Titan and Enceladus). The ability to image moving objects that might be missed utilizing a conventional TDI system is an added advantage and is particularly important for characterizing atmospheric effects and separating atmospheric and surface components. This can be accomplished with on-orbit processing or collecting and returning individual non co-added frames.
4D microvascular imaging based on ultrafast Doppler tomography.
Demené, Charlie; Tiran, Elodie; Sieu, Lim-Anna; Bergel, Antoine; Gennisson, Jean Luc; Pernot, Mathieu; Deffieux, Thomas; Cohen, Ivan; Tanter, Mickael
2016-02-15
4D ultrasound microvascular imaging was demonstrated by applying ultrafast Doppler tomography (UFD-T) to the imaging of brain hemodynamics in rodents. In vivo real-time imaging of the rat brain was performed using ultrasonic plane wave transmissions at very high frame rates (18,000 frames per second). Such ultrafast frame rates allow for highly sensitive and wide-field-of-view 2D Doppler imaging of blood vessels far beyond conventional ultrasonography. Voxel anisotropy (100 μm × 100 μm × 500 μm) was corrected for by using a tomographic approach, which consisted of ultrafast acquisitions repeated for different imaging plane orientations over multiple cardiac cycles. UFT-D allows for 4D dynamic microvascular imaging of deep-seated vasculature (up to 20 mm) with a very high 4D resolution (respectively 100 μm × 100 μm × 100 μm and 10 ms) and high sensitivity to flow in small vessels (>1 mm/s) for a whole-brain imaging technique without requiring any contrast agent. 4D ultrasound microvascular imaging in vivo could become a valuable tool for the study of brain hemodynamics, such as cerebral flow autoregulation or vascular remodeling after ischemic stroke recovery, and, more generally, tumor vasculature response to therapeutic treatment. Copyright © 2015 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Elahi, Sahar; Thrane, Lars; Rollins, Andrew M.; Jenkins, Michael W.
2017-02-01
The limited dynamic range of optical coherence tomography (OCT) Doppler velocity measurements makes it difficult to conduct experiments on samples requiring a large dynamic range without phase wrapping at high velocities or loss of sensitivity at slow velocities. Hemodynamics and wall motion undergo significant increases in velocity as the embryonic heart develops. Experimental studies indicate that altered hemodynamics in early-stage embryonic hearts can lead to congenital heart diseases (CHDs), motivating close monitoring of blood flow over several stages of development. We have built a high-speed OCT system using an FDML laser (Optores GmbH, Germany) at a sweep rate of 1.68 MHz (axial resolution - 12 μm, sensitivity - 105 dB, phase stability - 17 mrad). The speed of this OCT system allows us to acquire high-density B-scans to obtain an extended velocity dynamic range without sacrificing the frame rate (100 Hz). The extended dynamic range within a frame is achieved by varying the A-scan interval at which the phase difference is found, enabling detection of velocities ranging from tens of microns per second to hundreds of millimeters per second. The extra lines in a frame can also be utilized to improve the structural and Doppler images via complex averaging. In structural images where the presence of blood causes additional scattering, complex averaging helps retrieve features located deeper in the tissue. Moreover, high-density frames can be registered to 4D volumes to determine the orthogonal direction of flow for calculating shear stress as well as estimating the cardiac output. In conclusion, high density B-scans acquired by our high-speed OCT system enable image enhancement and direct measurement of biological parameters in cohort studies.
NASA Astrophysics Data System (ADS)
Harpsøe, K. B. W.; Jørgensen, U. G.; Andersen, M. I.; Grundahl, F.
2012-06-01
Context. The EMCCD is a type of CCD that delivers fast readout times and negligible readout noise, making it an ideal detector for high frame rate applications which improve resolution, like lucky imaging or shift-and-add. This improvement in resolution can potentially improve the photometry of faint stars in extremely crowded fields significantly by alleviating crowding. Alleviating crowding is a prerequisite for observing gravitational microlensing in main sequence stars towards the galactic bulge. However, the photometric stability of this device has not been assessed. The EMCCD has sources of noise not found in conventional CCDs, and new methods for handling these must be developed. Aims: We aim to investigate how the normal photometric reduction steps from conventional CCDs should be adjusted to be applicable to EMCCD data. One complication is that a bias frame cannot be obtained conventionally, as the output from an EMCCD is not normally distributed. Also, the readout process generates spurious charges in any CCD, but in EMCCD data, these charges are visible as opposed to the conventional CCD. Furthermore we aim to eliminate the photon waste associated with lucky imaging by combining this method with shift-and-add. Methods: A simple probabilistic model for the dark output of an EMCCD is developed. Fitting this model with the expectation-maximization algorithm allows us to estimate the bias, readout noise, amplification, and spurious charge rate per pixel and thus correct for these phenomena. To investigate the stability of the photometry, corrected frames of a crowded field are reduced with a point spread function (PSF) fitting photometry package, where a lucky image is used as a reference. Results: We find that it is possible to develop an algorithm that elegantly reduces EMCCD data and produces stable photometry at the 1% level in an extremely crowded field. Based on observation with the Danish 1.54 m telescope at ESO La Silla Observatory.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhang, Yu, E-mail: yuzhang@smu.edu.cn, E-mail: qianjinfeng08@gmail.com; Wu, Xiuxiu; Yang, Wei
2014-11-01
Purpose: The use of 4D computed tomography (4D-CT) of the lung is important in lung cancer radiotherapy for tumor localization and treatment planning. Sometimes, dense sampling is not acquired along the superior–inferior direction. This disadvantage results in an interslice thickness that is much greater than in-plane voxel resolutions. Isotropic resolution is necessary for multiplanar display, but the commonly used interpolation operation blurs images. This paper presents a super-resolution (SR) reconstruction method to enhance 4D-CT resolution. Methods: The authors assume that the low-resolution images of different phases at the same position can be regarded as input “frames” to reconstruct high-resolution images.more » The SR technique is used to recover high-resolution images. Specifically, the Demons deformable registration algorithm is used to estimate the motion field between different “frames.” Then, the projection onto convex sets approach is implemented to reconstruct high-resolution lung images. Results: The performance of the SR algorithm is evaluated using both simulated and real datasets. Their method can generate clearer lung images and enhance image structure compared with cubic spline interpolation and back projection (BP) method. Quantitative analysis shows that the proposed algorithm decreases the root mean square error by 40.8% relative to cubic spline interpolation and 10.2% versus BP. Conclusions: A new algorithm has been developed to improve the resolution of 4D-CT. The algorithm outperforms the cubic spline interpolation and BP approaches by producing images with markedly improved structural clarity and greatly reduced artifacts.« less
Fundamental Techniques for High Photon Energy Stability of a Modern Soft X-ray Beamline
DOE Office of Scientific and Technical Information (OSTI.GOV)
Senba, Yasunori; Kishimoto, Hikaru; Miura, Takanori
2007-01-19
High energy resolution and high energy stability are required for modern soft x-ray beamlines. Attempts at improving the energy stability are presented in this paper. Some measures have been adopted to avoid energy instability. It is clearly observed that the unstable temperature of the support frame of the optical elements results in photon energy instability. A photon energy stability of 10 meV for half a day is achieved by controlling the temperature with an accuracy of 0.01 deg. C.
Microradiography with Semiconductor Pixel Detectors
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jakubek, Jan; Cejnarova, Andrea; Dammer, Jiri
High resolution radiography (with X-rays, neutrons, heavy charged particles, ...) often exploited also in tomographic mode to provide 3D images stands as a powerful imaging technique for instant and nondestructive visualization of fine internal structure of objects. Novel types of semiconductor single particle counting pixel detectors offer many advantages for radiation imaging: high detection efficiency, energy discrimination or direct energy measurement, noiseless digital integration (counting), high frame rate and virtually unlimited dynamic range. This article shows the application and potential of pixel detectors (such as Medipix2 or TimePix) in different fields of radiation imaging.
Real time 3D visualization of intraoperative organ deformations using structured dictionary.
Wang, Dan; Tewfik, Ahmed H
2012-04-01
Restricted visualization of the surgical field is one of the most critical challenges for minimally invasive surgery (MIS). Current intraoperative visualization systems are promising. However, they can hardly meet the requirements of high resolution and real time 3D visualization of the surgical scene to support the recognition of anatomic structures for safe MIS procedures. In this paper, we present a new approach for real time 3D visualization of organ deformations based on optical imaging patches with limited field-of-view and a single preoperative scan of magnetic resonance imaging (MRI) or computed tomography (CT). The idea for reconstruction is motivated by our empirical observation that the spherical harmonic coefficients corresponding to distorted surfaces of a given organ lie in lower dimensional subspaces in a structured dictionary that can be learned from a set of representative training surfaces. We provide both theoretical and practical designs for achieving these goals. Specifically, we discuss details about the selection of limited optical views and the registration of partial optical images with a single preoperative MRI/CT scan. The design proposed in this paper is evaluated with both finite element modeling data and ex vivo experiments. The ex vivo test is conducted on fresh porcine kidneys using 3D MRI scans with 1.2 mm resolution and a portable laser scanner with an accuracy of 0.13 mm. Results show that the proposed method achieves a sub-3 mm spatial resolution in terms of Hausdorff distance when using only one preoperative MRI scan and the optical patch from the single-sided view of the kidney. The reconstruction frame rate is between 10 frames/s and 39 frames/s depending on the complexity of the test model.
High frequency ultrasound: a new frontier for ultrasound.
Shung, K; Cannata, Jonathan; Qifa Zhou, Member; Lee, Jungwoo
2009-01-01
High frequency ultrasonic imaging is considered by many to be the next frontier in ultrasonic imaging because higher frequencies yield much improved spatial resolution by sacrificing the depth of penetration. It has many clinical applications including visualizing blood vessel wall, anterior segments of the eye and skin. Another application is small animal imaging. Ultrasound is especially attractive in imaging the heart of a small animal like mouse which has a size in the mm range and a heart beat rate faster than 600 BPM. A majority of current commercial high frequency scanners often termed "ultrasonic backscatter microscope or UBM" acquire images by scanning single element transducers at frequencies between 50 to 80 MHz with a frame rate lower than 40 frames/s, making them less suitable for this application. High frequency linear arrays and linear array based ultrasonic imaging systems at frequencies higher than 30 MHz are being developed. The engineering of such arrays and development of high frequency imaging systems has been proven to be highly challenging. High frequency ultrasound may find other significant biomedical applications. The development of acoustic tweezers for manipulating microparticles is such an example.
NASA Astrophysics Data System (ADS)
Vitucci, G.; Minniti, T.; Tremsin, A. S.; Kockelmann, W.; Gorini, G.
2018-04-01
The MCP-based neutron counting detector is a novel device that allows high spatial resolution and time-resolved neutron radiography and tomography with epithermal, thermal and cold neutrons. Time resolution is possible by the high readout speeds of ~ 1200 frames/sec, allowing high resolution event counting with relatively high rates without spatial resolution degradation due to event overlaps. The electronic readout is based on a Timepix sensor, a CMOS pixel readout chip developed at CERN. Currently, a geometry of a quad Timepix detector is used with an active format of 28 × 28 mm2 limited by the size of the Timepix quad (2 × 2 chips) readout. Measurements of a set of high-precision micrometers test samples have been performed at the Imaging and Materials Science & Engineering (IMAT) beamline operating at the ISIS spallation neutron source (U.K.). The aim of these experiments was the full characterization of the chip misalignment and of the gaps between each pad in the quad Timepix sensor. Such misalignment causes distortions of the recorded shape of the sample analyzed. We present in this work a post-processing image procedure that considers and corrects these effects. Results of the correction will be discussed and the efficacy of this method evaluated.
Rise to SUMMIT: the Sydney University Multiple-Mirror Telescope
NASA Astrophysics Data System (ADS)
Moore, Anna M.; Davis, John
2000-07-01
The Sydney University Multiple Mirror Telescope (SUMMIT) is a medium-sized telescope designed specifically for high resolution stellar spectroscopy. Throughout the design emphasis has been placed on high efficiency at low cost. The telescope consists of four 0.46 m diameter mirrors mounted on a single welded steel frame. Specially designed mirror cells support and point each mirror, allowing accurate positioning of the images on optical fibers located at the foci of the mirrors. Four fibers convey the light to the future location of a high resolution spectrograph away from the telescope in a stable environment. An overview of the commissioning of the telescope is presented, including the guidance and automatic mirror alignment and focussing systems. SUMMIT is located alongside the Sydney University Stellar Interferometer at the Paul Wild Observatory, near Narrabri, Northern New South Wales.
Holographic line field en-face OCT with digital adaptive optics in the retina in vivo.
Ginner, Laurin; Schmoll, Tilman; Kumar, Abhishek; Salas, Matthias; Pricoupenko, Nastassia; Wurster, Lara M; Leitgeb, Rainer A
2018-02-01
We demonstrate a high-resolution line field en-face time domain optical coherence tomography (OCT) system using an off-axis holography configuration. Line field en-face OCT produces high speed en-face images at rates of up to 100 Hz. The high frame rate favors good phase stability across the lateral field-of-view which is indispensable for digital adaptive optics (DAO). Human retinal structures are acquired in-vivo with a broadband light source at 840 nm, and line rates of 10 kHz to 100 kHz. Structures of different retinal layers, such as photoreceptors, capillaries, and nerve fibers are visualized with high resolution of 2.8 µm and 5.5 µm in lateral directions. Subaperture based DAO is successfully applied to increase the visibility of cone-photoreceptors and nerve fibers. Furthermore, en-face Doppler OCT maps are generated based on calculating the differential phase shifts between recorded lines.
Ultra high resolution imaging of the human head at 8 tesla: 2K x 2K for Y2K.
Robitaille, P M; Abduljalil, A M; Kangarlu, A
2000-01-01
To acquire ultra high resolution MRI images of the human brain at 8 Tesla within a clinically acceptable time frame. Gradient echo images were acquired from the human head of normal subjects using a transverse electromagnetic resonator operating in quadrature and tuned to 340 MHz. In each study, a group of six images was obtained containing a total of 208 MB of unprocessed information. Typical acquisition parameters were as follows: matrix = 2,000 x 2,000, field of view = 20 cm, slice thickness = 2 mm, number of excitations (NEX) = 1, flip angle = 45 degrees, TR = 750 ms, TE = 17 ms, receiver bandwidth = 69.4 kHz. This resulted in a total scan time of 23 minutes, an in-plane resolution of 100 microm, and a pixel volume of 0.02 mm3. The ultra high resolution images acquired in this study represent more than a 50-fold increase in in-plane resolution relative to conventional 256 x 256 images obtained with a 20 cm field of view and a 5 mm slice thickness. Nonetheless, the ultra high resolution images could be acquired both with adequate image quality and signal to noise. They revealed numerous small venous structures throughout the image plane and provided reasonable delineation between gray and white matter. The elevated signal-to-noise ratio observed in ultra high field magnetic resonance imaging can be utilized to acquire images with a level of resolution approaching the histological level under in vivo conditions. However, brain motion is likely to degrade the useful resolution. This situation may be remedied in part with cardiac gating. Nonetheless, these images represent a significant advance in our ability to examine small anatomical features with noninvasive imaging methods.
Evaluation of a High-Resolution Benchtop Micro-CT Scanner for Application in Porous Media Research
NASA Astrophysics Data System (ADS)
Tuller, M.; Vaz, C. M.; Lasso, P. O.; Kulkarni, R.; Ferre, T. A.
2010-12-01
Recent advances in Micro Computed Tomography (MCT) provided the motivation to thoroughly evaluate and optimize scanning, image reconstruction/segmentation and pore-space analysis capabilities of a new generation benchtop MCT scanner and associated software package. To demonstrate applicability to soil research the project was focused on determination of porosities and pore size distributions of two Brazilian Oxisols from segmented MCT-data. Effects of metal filters and various acquisition parameters (e.g. total rotation, rotation step, and radiograph frame averaging) on image quality and acquisition time are evaluated. Impacts of sample size and scanning resolution on CT-derived porosities and pore-size distributions are illustrated.
Formulation of image fusion as a constrained least squares optimization problem
Dwork, Nicholas; Lasry, Eric M.; Pauly, John M.; Balbás, Jorge
2017-01-01
Abstract. Fusing a lower resolution color image with a higher resolution monochrome image is a common practice in medical imaging. By incorporating spatial context and/or improving the signal-to-noise ratio, it provides clinicians with a single frame of the most complete information for diagnosis. In this paper, image fusion is formulated as a convex optimization problem that avoids image decomposition and permits operations at the pixel level. This results in a highly efficient and embarrassingly parallelizable algorithm based on widely available robust and simple numerical methods that realizes the fused image as the global minimizer of the convex optimization problem. PMID:28331885
Modulating complex beams in amplitude and phase using fast tilt-micromirror arrays and phase masks.
Roth, Matthias; Heber, Jörg; Janschek, Klaus
2018-06-15
The Letter proposes a system for the spatial modulation of light in amplitude and phase at kilohertz frame rates and high spatial resolution. The focus is fast spatial light modulators (SLMs) consisting of continuously tiltable micromirrors. We investigate the utilization of such SLMs in combination with a static phase mask in a 4f setup. The phase mask enables the complex beam modulation in a linear optical arrangement. Furthermore, adding so-called phase steps to the phase mask increases both the number of image pixels at constant SLM resolution and the optical efficiency. We illustrate our concept based on numerical simulations.
Castellano-Muñoz, Manuel; Peng, Anthony Wei; Salles, Felipe T.; Ricci, Anthony J.
2013-01-01
Confocal fluorescence microscopy is a broadly used imaging technique that enhances the signal-to-noise ratio by removing out of focal plane fluorescence. Confocal microscopes come with a variety of modifications depending on the particular experimental goals. Microscopes, illumination pathways, and light collection were originally focused upon obtaining the highest resolution image possible, typically on fixed tissue. More recently, live-cell confocal imaging has gained importance. Since measured signals are often rapid or transient, thus requiring higher sampling rates, specializations are included to enhance spatial and temporal resolution while maintaining tissue viability. Thus, a balance between image quality, temporal resolution, and tissue viability is needed. A subtype of confocal imaging, termed swept field confocal (SFC) microscopy, can image live cells at high rates while maintaining confocality. SFC systems can use a pinhole array to obtain high spatial resolution, similar to spinning disc systems. In addition, SFC imaging can achieve faster rates by using a slit to sweep the light across the entire image plane, thus requiring a single scan to generate an image. Coupled to a high-speed charge-coupled device camera and a laser illumination source, images can be obtained at greater than 1,000 frames per second while maintaining confocality. PMID:22831554
NASA Astrophysics Data System (ADS)
Schultz, C. J.; Lang, T. J.; Leake, S.; Runco, M.; Blakeslee, R. J.
2017-12-01
Video and still frame images from cameras aboard the International Space Station (ISS) are used to inspire, educate, and provide a unique vantage point from low-Earth orbit that is second to none; however, these cameras have overlooked capabilities for contributing to scientific analysis of the Earth and near-space environment. The goal of this project is to study how georeferenced video/images from available ISS camera systems can be useful for scientific analysis, using lightning properties as a demonstration. Camera images from the crew cameras and high definition video from the Chiba University Meteor Camera were combined with lightning data from the National Lightning Detection Network (NLDN), ISS-Lightning Imaging Sensor (ISS-LIS), the Geostationary Lightning Mapper (GLM) and lightning mapping arrays. These cameras provide significant spatial resolution advantages ( 10 times or better) over ISS-LIS and GLM, but with lower temporal resolution. Therefore, they can serve as a complementarity analysis tool for studying lightning and thunderstorm processes from space. Lightning sensor data, Visible Infrared Imaging Radiometer Suite (VIIRS) derived city light maps, and other geographic databases were combined with the ISS attitude and position data to reverse geolocate each image or frame. An open-source Python toolkit has been developed to assist with this effort. Next, the locations and sizes of all flashes in each frame or image were computed and compared with flash characteristics from all available lightning datasets. This allowed for characterization of cloud features that are below the 4-km and 8-km resolution of ISS-LIS and GLM which may reduce the light that reaches the ISS-LIS or GLM sensor. In the case of video, consecutive frames were overlaid to determine the rate of change of the light escaping cloud top. Characterization of the rate of change in geometry, more generally the radius, of light escaping cloud top was integrated with the NLDN, ISS-LIS and GLM to understand how the peak rate of change and the peak area of each flash aligned with each lightning system in time. Flash features like leaders could be inferred from the video frames as well. Testing is being done to see if leader speeds may be accurately calculated under certain circumstances.
Practical low-cost visual communication using binary images for deaf sign language.
Manoranjan, M D; Robinson, J A
2000-03-01
Deaf sign language transmitted by video requires a temporal resolution of 8 to 10 frames/s for effective communication. Conventional videoconferencing applications, when operated over low bandwidth telephone lines, provide very low temporal resolution of pictures, of the order of less than a frame per second, resulting in jerky movement of objects. This paper presents a practical solution for sign language communication, offering adequate temporal resolution of images using moving binary sketches or cartoons, implemented on standard personal computer hardware with low-cost cameras and communicating over telephone lines. To extract cartoon points an efficient feature extraction algorithm adaptive to the global statistics of the image is proposed. To improve the subjective quality of the binary images, irreversible preprocessing techniques, such as isolated point removal and predictive filtering, are used. A simple, efficient and fast recursive temporal prefiltering scheme, using histograms of successive frames, reduces the additive and multiplicative noise from low-cost cameras. An efficient three-dimensional (3-D) compression scheme codes the binary sketches. Subjective tests performed on the system confirm that it can be used for sign language communication over telephone lines.
Water Management Applications of Advanced Precipitation Products
NASA Astrophysics Data System (ADS)
Johnson, L. E.; Braswell, G.; Delaney, C.
2012-12-01
Advanced precipitation sensors and numerical models track storms as they occur and forecast the likelihood of heavy rain for time frames ranging from 1 to 8 hours, 1 day, and extended outlooks out to 3 to 7 days. Forecast skill decreases at the extended time frames but the outlooks have been shown to provide "situational awareness" which aids in preparation for flood mitigation and water supply operations. In California the California-Nevada River Forecast Centers and local Weather Forecast Offices provide precipitation products that are widely used to support water management and flood response activities of various kinds. The Hydrometeorology Testbed (HMT) program is being conducted to help advance the science of precipitation tracking and forecasting in support of the NWS. HMT high-resolution products have found applications for other non-federal water management activities as well. This presentation will describe water management applications of HMT advanced precipitation products, and characterization of benefits expected to accrue. Two case examples will be highlighted, 1) reservoir operations for flood control and water supply, and 2) urban stormwater management. Application of advanced precipitation products in support of reservoir operations is a focus of the Sonoma County Water Agency. Examples include: a) interfacing the high-resolution QPE products with a distributed hydrologic model for the Russian-Napa watersheds, b) providing early warning of in-coming storms for flood preparedness and water supply storage operations. For the stormwater case, San Francisco wastewater engineers are developing a plan to deploy high resolution gap-filling radars looking off shore to obtain longer lead times on approaching storms. A 4 to 8 hour lead time would provide opportunity to optimize stormwater capture and treatment operations, and minimize combined sewer overflows into the Bay.ussian River distributed hydrologic model.
Sakabe, N; Sakabe, K; Sasaki, K
2004-01-01
Galaxy is a Weissenberg-type high-speed high-resolution and highly accurate fully automatic data-collection system using two cylindrical IP-cassettes each with a radius of 400 mm and a width of 450 mm. It was originally developed for static three-dimensional analysis using X-ray diffraction and was installed on bending-magnet beamline BL6C at the Photon Factory. It was found, however, that Galaxy was also very useful for time-resolved protein crystallography on a time scale of minutes. This has prompted us to design a new IP-conveyor-belt Weissenberg-mode data-collection system called Super Galaxy for time-resolved crystallography with improved time and crystallographic resolution over that achievable with Galaxy. Super Galaxy was designed with a half-cylinder-shaped cassette with a radius of 420 mm and a width of 690 mm. Using 1.0 A incident X-rays, these dimensions correspond to a maximum resolutions of 0.71 A in the vertical direction and 1.58 A in the horizontal. Upper and lower screens can be used to set the frame size of the recorded image. This function is useful not only to reduce the frame exchange time but also to save disk space on the data server. The use of an IP-conveyor-belt and many IP-readers make Super Galaxy well suited for time-resolved, monochromatic X-ray crystallography at a very intense third-generation SR beamline. Here, Galaxy and a conceptual design for Super Galaxy are described, and their suitability for use as data-collection systems for macromolecular time-resolved monochromatic X-ray crystallography are compared.
Tracking quasi-stationary flow of weak fluorescent signals by adaptive multi-frame correlation.
Ji, L; Danuser, G
2005-12-01
We have developed a novel cross-correlation technique to probe quasi-stationary flow of fluorescent signals in live cells at a spatial resolution that is close to single particle tracking. By correlating image blocks between pairs of consecutive frames and integrating their correlation scores over multiple frame pairs, uncertainty in identifying a globally significant maximum in the correlation score function has been greatly reduced as compared with conventional correlation-based tracking using the signal of only two consecutive frames. This approach proves robust and very effective in analysing images with a weak, noise-perturbed signal contrast where texture characteristics cannot be matched between only a pair of frames. It can also be applied to images that lack prominent features that could be utilized for particle tracking or feature-based template matching. Furthermore, owing to the integration of correlation scores over multiple frames, the method can handle signals with substantial frame-to-frame intensity variation where conventional correlation-based tracking fails. We tested the performance of the method by tracking polymer flow in actin and microtubule cytoskeleton structures labelled at various fluorophore densities providing imagery with a broad range of signal modulation and noise. In applications to fluorescent speckle microscopy (FSM), where the fluorophore density is sufficiently low to reveal patterns of discrete fluorescent marks referred to as speckles, we combined the multi-frame correlation approach proposed above with particle tracking. This hybrid approach allowed us to follow single speckles robustly in areas of high speckle density and fast flow, where previously published FSM analysis methods were unsuccessful. Thus, we can now probe cytoskeleton polymer dynamics in living cells at an entirely new level of complexity and with unprecedented detail.
Modeling of digital information optical encryption system with spatially incoherent illumination
NASA Astrophysics Data System (ADS)
Bondareva, Alyona P.; Cheremkhin, Pavel A.; Krasnov, Vitaly V.; Rodin, Vladislav G.; Starikov, Rostislav S.; Starikov, Sergey N.
2015-10-01
State of the art micromirror DMD spatial light modulators (SLM) offer unprecedented framerate up to 30000 frames per second. This, in conjunction with high speed digital camera, should allow to build high speed optical encryption system. Results of modeling of digital information optical encryption system with spatially incoherent illumination are presented. Input information is displayed with first SLM, encryption element - with second SLM. Factors taken into account are: resolution of SLMs and camera, holograms reconstruction noise, camera noise and signal sampling. Results of numerical simulation demonstrate high speed (several gigabytes per second), low bit error rate and high crypto-strength.
Ultra High Definition Video from the International Space Station (Reel 1)
2015-06-15
The view of life in space is getting a major boost with the introduction of 4K Ultra High-Definition (UHD) video, providing an unprecedented look at what it's like to live and work aboard the International Space Station. This important new capability will allow researchers to acquire high resolution - high frame rate video to provide new insight into the vast array of experiments taking place every day. It will also bestow the most breathtaking views of planet Earth and space station activities ever acquired for consumption by those still dreaming of making the trip to outer space.
Three-dimensional optical coherence tomography of the embryonic murine cardiovascular system
NASA Astrophysics Data System (ADS)
Luo, Wei; Marks, Daniel L.; Ralston, Tyler S.; Boppart, Stephen A.
2006-03-01
Optical coherence tomography (OCT) is an emerging high-resolution real-time biomedical imaging technology that has potential as a novel investigational tool in developmental biology and functional genomics. In this study, murine embryos and embryonic hearts are visualized with an OCT system capable of 2-µm axial and 15-µm lateral resolution and with real-time acquisition rates. We present, to our knowledge, the first sets of high-resolution 2- and 3-D OCT images that reveal the internal structures of the mammalian (murine) embryo (E10.5) and embryonic (E14.5 and E17.5) cardiovascular system. Strong correlations are observed between OCT images and corresponding hematoxylin- and eosin-stained histological sections. Real-time in vivo embryonic (E10.5) heart activity is captured by spectral-domain optical coherence tomography, processed, and displayed at a continuous rate of five frames per second. With the ability to obtain not only high-resolution anatomical data but also functional information during cardiovascular development, the OCT technology has the potential to visualize and quantify changes in murine development and in congenital and induced heart disease, as well as enable a wide range of basic in vitro and in vivo research studies in functional genomics.
Power cavitation-guided blood-brain barrier opening with focused ultrasound and microbubbles
NASA Astrophysics Data System (ADS)
Burgess, M. T.; Apostolakis, I.; Konofagou, E. E.
2018-03-01
Image-guided monitoring of microbubble-based focused ultrasound (FUS) therapies relies on the accurate localization of FUS-stimulated microbubble activity (i.e. acoustic cavitation). Passive cavitation imaging with ultrasound arrays can achieve this, but with insufficient spatial resolution. In this study, we address this limitation and perform high-resolution monitoring of acoustic cavitation-mediated blood-brain barrier (BBB) opening with a new technique called power cavitation imaging. By synchronizing the FUS transmit and passive receive acquisition, high-resolution passive cavitation imaging was achieved by using delay and sum beamforming with absolute time delays. Since the axial image resolution is now dependent on the duration of the received acoustic cavitation emission, short pulses of FUS were used to limit its duration. Image sets were acquired at high-frame rates for calculation of power cavitation images analogous to power Doppler imaging. Power cavitation imaging displays the mean intensity of acoustic cavitation over time and was correlated with areas of acoustic cavitation-induced BBB opening. Power cavitation-guided BBB opening with FUS could constitute a standalone system that may not require MRI guidance during the procedure. The same technique can be used for other acoustic cavitation-based FUS therapies, for both safety and guidance.
Power cavitation-guided blood-brain barrier opening with focused ultrasound and microbubbles.
Burgess, M T; Apostolakis, I; Konofagou, E E
2018-03-15
Image-guided monitoring of microbubble-based focused ultrasound (FUS) therapies relies on the accurate localization of FUS-stimulated microbubble activity (i.e. acoustic cavitation). Passive cavitation imaging with ultrasound arrays can achieve this, but with insufficient spatial resolution. In this study, we address this limitation and perform high-resolution monitoring of acoustic cavitation-mediated blood-brain barrier (BBB) opening with a new technique called power cavitation imaging. By synchronizing the FUS transmit and passive receive acquisition, high-resolution passive cavitation imaging was achieved by using delay and sum beamforming with absolute time delays. Since the axial image resolution is now dependent on the duration of the received acoustic cavitation emission, short pulses of FUS were used to limit its duration. Image sets were acquired at high-frame rates for calculation of power cavitation images analogous to power Doppler imaging. Power cavitation imaging displays the mean intensity of acoustic cavitation over time and was correlated with areas of acoustic cavitation-induced BBB opening. Power cavitation-guided BBB opening with FUS could constitute a standalone system that may not require MRI guidance during the procedure. The same technique can be used for other acoustic cavitation-based FUS therapies, for both safety and guidance.
Feedback Linearization in a Six Degree-of-Freedom MAG-LEV Stage
NASA Technical Reports Server (NTRS)
Ludwick, Stephen J.; Trumper, David L.; Holmes, Michael L.
1996-01-01
A six degree-of-freedom electromagnetically suspended motion control stage (the Angstrom Stage) has been designed and constructed for use in short-travel, high-resolution motion control applications. It achieves better than 0.5 nm resolution over a 100 micron range of travel. The stage consists of a single moving element (the platen) floating in an oil filled chamber. The oil is crucial to the stage's operation since it forms squeeze film dampers between the platen and the frame. Twelve electromagnetic actuators provide the forces necessary to suspend and servo the platen, and six capacitance probes measure its position relative to the frame. The system is controlled using a digital signal processing board residing in a '486 based PC. This digital controller implements a feedback linearization algorithm in real-time to account for nonlinearities in both the magnetic actuators and the fluid film dampers. The feedback linearization technique reduces a highly nonlinear plant with coupling between the degrees of freedom into one that is linear, decoupled, and setpoint independent. The key to this procedure is a detailed plant model. The operation of the feedback linearization procedure is transparent to the outer loop of the controller, and so a proportional controller is sufficient for normal operation. We envision applications of this stage in scanned probe microscopy and for integrated circuit measurement.
The design of light pipe with microstructures for touch screen
NASA Astrophysics Data System (ADS)
Yang, Bo; Lu, Kan; Liu, Pengfei; Wei, Xiaona
2010-11-01
Touch screen has a very wide range of applications. Most of them are used in public information inquiries, for instance, service inquiries in telecommunication bureau, tax bureau, bank system, electric department, etc...Touch screen can also be used for entertainment and virtual reality applications too. Traditionally, touch screen was composed of pairs of infrared LED and correspondent receivers which were all installed in the screen frame. Arrays of LED were set in the adjacent sides of the frame of an infrared touch screen while arrays of the infrared receivers were fixed in each opposite side, so that the infrared detecting network was formed. While the infrared touch screen has some technical limitations nowadays such as the low resolution, limitations of touching methods and fault response due to environmental disturbances. The plastic material has a relatively high absorption rate for infrared light, which greatly limits the size of the touch screen. Our design uses laser diode as source and change the traditional inner structure of touch screen by using a light pipe with microstructures. The geometric parameters of the light pipe and the microstructures were obtained through equation solving. Simulation results prove that the design method for touch screen proposed in this paper could achieve high resolution and large size of touch screen.
Parallel Implementation of a Frozen Flow Based Wavefront Reconstructor
NASA Astrophysics Data System (ADS)
Nagy, J.; Kelly, K.
2013-09-01
Obtaining high resolution images of space objects from ground based telescopes is challenging, often requiring the use of a multi-frame blind deconvolution (MFBD) algorithm to remove blur caused by atmospheric turbulence. In order for an MFBD algorithm to be effective, it is necessary to obtain a good initial estimate of the wavefront phase. Although wavefront sensors work well in low turbulence situations, they are less effective in high turbulence, such as when imaging in daylight, or when imaging objects that are close to the Earth's horizon. One promising approach, which has been shown to work very well in high turbulence settings, uses a frozen flow assumption on the atmosphere to capture the inherent temporal correlations present in consecutive frames of wavefront data. Exploiting these correlations can lead to more accurate estimation of the wavefront phase, and the associated PSF, which leads to more effective MFBD algorithms. However, with the current serial implementation, the approach can be prohibitively expensive in situations when it is necessary to use a large number of frames. In this poster we describe a parallel implementation that overcomes this constraint. The parallel implementation exploits sparse matrix computations, and uses the Trilinos package developed at Sandia National Laboratories. Trilinos provides a variety of core mathematical software for parallel architectures that have been designed using high quality software engineering practices, The package is open source, and portable to a variety of high-performance computing architectures.
Northeast View From Pathfinder Lander
NASA Technical Reports Server (NTRS)
1997-01-01
This panorama of the region to the northeast of the lander was constructed to support the Sojourner Rover Team's plans to conduct an 'autonomous traverse' to explore the terrain away from the lander after science objectives in the lander vicinity had been met. The large, relatively bright surface in the foreground, about 10 meters (33 feet) from the spacecraft, in this scene is 'Baker's Bench.' The large, elongated rock left of center in the middle distance is 'Zaphod.'
This view was produced by combining 8 individual 'Superpan' scenes from the left and right eyes of the IMP camera. Each frame consists of 8 individual frames (left eye) and 7 frames (right eye) taken with different color filters that were enlarged by 500% and then co-added using Adobe Photoshop to produce, in effect, a super-resolution panchromatic frame that is sharper than an individual frame would be.Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is a division of the California Institute of Technology (Caltech). The IMP was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.Yoo, Sun K; Kim, D K; Jung, S M; Kim, E-K; Lim, J S; Kim, J H
2004-01-01
A Web-based, realtime, tele-ultrasound consultation system was designed. The system employed ActiveX control, MPEG-4 coding of full-resolution ultrasound video (640 x 480 pixels at 30 frames/s) and H.320 videoconferencing. It could be used via a Web browser. The system was evaluated over three types of commercial line: a cable connection, ADSL and VDSL. Three radiologists assessed the quality of compressed and uncompressed ultrasound video-sequences from 16 cases (10 abnormal livers, four abnormal kidneys and two abnormal gallbladders). The radiologists' scores showed that, at a given frame rate, increasing the bit rate was associated with increasing quality; however, at a certain threshold bit rate the quality did not increase significantly. The peak signal to noise ratio (PSNR) was also measured between the compressed and uncompressed images. In most cases, the PSNR increased as the bit rate increased, and increased as the number of dropped frames increased. There was a threshold bit rate, at a given frame rate, at which the PSNR did not improve significantly. Taking into account both sets of threshold values, a bit rate of more than 0.6 Mbit/s, at 30 frames/s, is suggested as the threshold for the maintenance of diagnostic image quality.
Nakamura, Masanobu; Yoneyama, Masami; Tabuchi, Takashi; Takemura, Atsushi; Obara, Makoto; Sawano, Seishi
2012-01-01
Detailed information on anatomy and hemodynamics in cerebrovascular disorders such as AVM and Moyamoya disease is mandatory for defined diagnosis and treatment planning. Arterial spin labeling technique has come to be applied to magnetic resonance angiography (MRA) and perfusion imaging in recent years. However, those non-contrast techniques are mostly limited to single frame images. Recently we have proposed a non-contrast time-resolved MRA technique termed contrast inherent inflow enhanced multi phase angiography combining spatial resolution echo planar imaging based signal targeting and alternating radiofrequency (CINEMA-STAR). CINEMA-STAR can extract the blood flow in the major intracranial arteries at an interval of 70 ms and thus permits us to observe vascular construction in full by preparing MIP images of axial acquisitions with high spatial resolution. This preliminary study demonstrates the usefulness of the CINEMA-STAR technique in evaluating the cerebral vasculature.
A High Spatial Resolution Depth Sensing Method Based on Binocular Structured Light
Yao, Huimin; Ge, Chenyang; Xue, Jianru; Zheng, Nanning
2017-01-01
Depth information has been used in many fields because of its low cost and easy availability, since the Microsoft Kinect was released. However, the Kinect and Kinect-like RGB-D sensors show limited performance in certain applications and place high demands on accuracy and robustness of depth information. In this paper, we propose a depth sensing system that contains a laser projector similar to that used in the Kinect, and two infrared cameras located on both sides of the laser projector, to obtain higher spatial resolution depth information. We apply the block-matching algorithm to estimate the disparity. To improve the spatial resolution, we reduce the size of matching blocks, but smaller matching blocks generate lower matching precision. To address this problem, we combine two matching modes (binocular mode and monocular mode) in the disparity estimation process. Experimental results show that our method can obtain higher spatial resolution depth without loss of the quality of the range image, compared with the Kinect. Furthermore, our algorithm is implemented on a low-cost hardware platform, and the system can support the resolution of 1280 × 960, and up to a speed of 60 frames per second, for depth image sequences. PMID:28397759
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pravdivtsev, Andrey N.; Yurkovskaya, Alexandra V.; Ivanov, Konstantin L., E-mail: ivanov@tomo.nsc.ru
2014-10-21
Nuclear Magnetic Relaxation Dispersion (NMRD) of protons was studied in the pentapeptide Met-enkephalin and the amino acids, which constitute it. Experiments were run by using high-resolution Nuclear Magnetic Resonance (NMR) in combination with fast field-cycling, thus enabling measuring NMRD curves for all individual protons. As in earlier works, Papers I–III, pronounced effects of intramolecular scalar spin-spin interactions, J-couplings, on spin relaxation were found. Notably, at low fields J-couplings tend to equalize the apparent relaxation rates within networks of coupled protons. In Met-enkephalin, in contrast to the free amino acids, there is a sharp increase in the proton T{sub 1}-relaxation timesmore » at high fields due to the changes in the regime of molecular motion. The experimental data are in good agreement with theory. From modelling the relaxation experiments we were able to determine motional correlation times of different residues in Met-enkephalin with atomic resolution. This allows us to draw conclusions about preferential conformation of the pentapeptide in solution, which is also in agreement with data from two-dimensional NMR experiments (rotating frame Overhauser effect spectroscopy). Altogether, our study demonstrates that high-resolution NMR studies of magnetic field-dependent relaxation allow one to probe molecular mobility in biomolecules with atomic resolution.« less
A New Hyperspectral Designed for Small UAS Tested in Real World Applications
NASA Astrophysics Data System (ADS)
Marcucci, E.; Saiet, E., II; Hatfield, M. C.
2014-12-01
The ability to investigate landscape and vegetation from airborne instruments offers many advantages, including high resolution data, ability to deploy instruments over a specific area, and repeat measurements. The Alaska Center for Unmanned Aircraft Systems Integration (ACUASI) has recently integrated a hyperspectral imaging camera onto their Ptarmigan hexacopter. The Rikola Hyperspectral Camera manufactured by VTT and Rikola, Ltd. is capable of obtaining data within the 400-950 nm range with an accuracy of ~1 nm. Using the compact flash on the UAV limits the maximum number of channels to 24 this summer. The camera uses a single frame to sequentially record the spectral bands of interest in a 37° field-of-view. Because the camera collects data as single frames it takes a finite amount of time to compile the complete spectral. Although each frame takes only 5 nanoseconds, co-registration of frames is still required. The hovering ability of the hexacopter helps eliminate frame shift. GPS records data for incorporation into a larger dataset. Conservatively, the Ptarmigan can fly at an altitude of 400 feet, for 15 minutes, and 7000 feet away from the operator. The airborne hyperspectral instrument will be extremely useful to scientists as a platform that can provide data on-request. Since the spectral range of the camera is ideal for the study of vegetation, this study 1) examines seasonal changes of vegetation of the Fairbanks area, 2) ground-truths satellite measurements, and 3) ties vegetation conditions around a weather tower to the tower readings. Through this proof of concept, ACUASI provides a means for scientists to request the most up-to-date and location-specific data for their field sites. Additionally, the resolution of the airborne instruments is much higher than that of satellite data, these may be readily tasked, and they have the advantage over manned flights in terms of manpower and cost.
The NASA Soil Moisture Active Passive (SMAP) Mission: Overview
NASA Technical Reports Server (NTRS)
O'Neill, Peggy; Entekhabi, Dara; Njoku, Eni; Kellogg, Kent
2011-01-01
The Soil Moisture Active Passive (SMAP) mission is one of the first Earth observation satellites being developed by NASA in response to the National Research Council?s Decadal Survey [1]. Its mission design consists of L-band radiometer and radar instruments sharing a rotating 6-m mesh reflector antenna to provide high-resolution and high-accuracy global maps of soil moisture and freeze/thaw state every 2-3 days. The combined active/passive microwave soil moisture product will have a spatial resolution of 10 km and a mean latency of 24 hours. In addition, the SMAP surface observations will be combined with advanced modeling and data assimilation to provide deeper root zone soil moisture and net ecosystem exchange of carbon. SMAP is expected to launch in the late 2014 - early 2015 time frame.
Discovery of Finely Structured Dynamic Solar Corona Observed in the Hi-C Telescope
NASA Technical Reports Server (NTRS)
Winebarger, A.; Cirtain, J.; Golub, L.; DeLuca, E.; Savage, S.; Alexander, C.; Schuler, T.
2014-01-01
In the summer of 2012, the High-resolution Coronal Imager (Hi-C) flew aboard a NASA sounding rocket and collected the highest spatial resolution images ever obtained of the solar corona. One of the goals of the Hi-C flight was to characterize the substructure of the solar corona. We therefore examine how the intensity scales from AIA resolution to Hi-C resolution. For each low-resolution pixel, we calculate the standard deviation in the contributing high-resolution pixel intensities and compare that to the expected standard deviation calculated from the noise. If these numbers are approximately equal, the corona can be assumed to be smoothly varying, i.e. have no evidence of substructure in the Hi-C image to within Hi-C's ability to measure it given its throughput and readout noise. A standard deviation much larger than the noise value indicates the presence of substructure. We calculate these values for each low-resolution pixel for each frame of the Hi-C data. On average, 70 percent of the pixels in each Hi-C image show no evidence of substructure. The locations where substructure is prevalent is in the moss regions and in regions of sheared magnetic field. We also find that the level of substructure varies significantly over the roughly 160 s of the Hi-C data analyzed here. This result indicates that the finely structured corona is concentrated in regions of heating and is highly time dependent.
DISCOVERY OF FINELY STRUCTURED DYNAMIC SOLAR CORONA OBSERVED IN THE Hi-C TELESCOPE
DOE Office of Scientific and Technical Information (OSTI.GOV)
Winebarger, Amy R.; Cirtain, Jonathan; Savage, Sabrina
In the Summer of 2012, the High-resolution Coronal Imager (Hi-C) flew on board a NASA sounding rocket and collected the highest spatial resolution images ever obtained of the solar corona. One of the goals of the Hi-C flight was to characterize the substructure of the solar corona. We therefore examine how the intensity scales from AIA resolution to Hi-C resolution. For each low-resolution pixel, we calculate the standard deviation in the contributing high-resolution pixel intensities and compare that to the expected standard deviation calculated from the noise. If these numbers are approximately equal, the corona can be assumed to bemore » smoothly varying, i.e., have no evidence of substructure in the Hi-C image to within Hi-C's ability to measure it given its throughput and readout noise. A standard deviation much larger than the noise value indicates the presence of substructure. We calculate these values for each low-resolution pixel for each frame of the Hi-C data. On average, 70% of the pixels in each Hi-C image show no evidence of substructure. The locations where substructure is prevalent is in the moss regions and in regions of sheared magnetic field. We also find that the level of substructure varies significantly over the roughly 160 s of the Hi-C data analyzed here. This result indicates that the finely structured corona is concentrated in regions of heating and is highly time dependent.« less
Performance evaluation of the CT component of the IRIS PET/CT preclinical tomograph
NASA Astrophysics Data System (ADS)
Panetta, Daniele; Belcari, Nicola; Tripodi, Maria; Burchielli, Silvia; Salvadori, Piero A.; Del Guerra, Alberto
2016-01-01
In this paper, we evaluate the physical performance of the CT component of the IRIS scanner, a novel combined PET/CT scanner for preclinical imaging. The performance assessment is based on phantom measurement for the determination of image quality parameters (spatial resolution, linearity, geometric accuracy, contrast to noise ratio) and reproducibility in dynamic (4D) imaging. The CTDI100 has been measured free in air with a pencil ionization chamber, and the animal dose was calculated using Monte Carlo derived conversion factors taken from the literature. The spatial resolution at the highest quality protocol was 6.9 lp/mm at 10% of the MTF, using the smallest reconstruction voxel size of 58.8 μm. The accuracy of the reconstruction voxel size was within 0.1%. The linearity of the CT numbers as a function of the concentration of iodine was very good, with R2>0.996 for all the tube voltages. The animal dose depended strongly on the scanning protocol, ranging from 158 mGy for the highest quality protocol (2 min, 80 kV) to about 12 mGy for the fastest protocol (7.3 s, 80 kV). In 4D dynamic modality, the maximum scanning rate reached was 3.1 frames per minute, using a short-scan protocol with 7.3 s of scan time per frame at the isotropic voxel size of 235 μm. The reproducibility of the system was high throughout the 10 frames acquired in dynamic modality, with a standard deviation of the CT values of all frames <8 HU and an average spatial reproducibility within 30% of the voxel size across all the field of view. Example images obtained during animal experiments are also shown.
Single image super resolution algorithm based on edge interpolation in NSCT domain
NASA Astrophysics Data System (ADS)
Zhang, Mengqun; Zhang, Wei; He, Xinyu
2017-11-01
In order to preserve the texture and edge information and to improve the space resolution of single frame, a superresolution algorithm based on Contourlet (NSCT) is proposed. The original low resolution image is transformed by NSCT, and the directional sub-band coefficients of the transform domain are obtained. According to the scale factor, the high frequency sub-band coefficients are amplified by the interpolation method based on the edge direction to the desired resolution. For high frequency sub-band coefficients with noise and weak targets, Bayesian shrinkage is used to calculate the threshold value. The coefficients below the threshold are determined by the correlation among the sub-bands of the same scale to determine whether it is noise and de-noising. The anisotropic diffusion filter is used to effectively enhance the weak target in the low contrast region of the target and background. Finally, the high-frequency sub-band is amplified by the bilinear interpolation method to the desired resolution, and then combined with the high-frequency subband coefficients after de-noising and small target enhancement, the NSCT inverse transform is used to obtain the desired resolution image. In order to verify the effectiveness of the proposed algorithm, the proposed algorithm and several common image reconstruction methods are used to test the synthetic image, motion blurred image and hyperspectral image, the experimental results show that compared with the traditional single resolution algorithm, the proposed algorithm can obtain smooth edges and good texture features, and the reconstructed image structure is well preserved and the noise is suppressed to some extent.
Lightning Step Leader and Return Stroke Spectra at 100,000 fps
NASA Astrophysics Data System (ADS)
Harley, J.; McHarg, M.; Stenbaek-Nielsen, H. C.; Haaland, R. K.; Sonnenfeld, R.; Edens, H. E.; Cummer, S.; Lapierre, J. L.; Maddocks, S.
2017-12-01
A fundamental understanding of lightning can be inferred from the spectral emissions resulting from the leader and return stroke channels. We examine events recorded at 00:58:07 on 19 July 2015 and 06:44:24 on 23 July 2017, both at Langmuir Laboratory. Analysis of both events is supplemented by data from the Lightning Mapping Array at Langmuir. The 00:58:07 event spectra was recorded using a 100 line per mm grating in front of a Phantom V2010 camera with an 85mm (9o FOV) Nikon lens recording at 100,000 frames per second. Coarse resolution spectra (approximately 5 nm resolution) are produced from approximately 400 nm to 800 nm for each frame. We analyze several nitrogen and oxygen lines to understand step leader temperature behavior between cloud and ground. The 06:44:24 event spectra was recorded using a 300 line per mm grating (approximately 1.5 nm resolution) in front of a Phantom V2010 camera with an 50mm (32o FOV) Nikon lens also recording at 100,000 frames per second. Two ionized atomic nitrogen lines at 502 nm and 569 nm appear upon attachment and disappear as the return stroke travels from ground to cloud in approximately 5 frames. We analyze these lines to understand initial return stroke temperature and species behavior.
SolTrack: an automatic video processing software for in situ interface tracking.
Griesser, S; Pierer, R; Reid, M; Dippenaar, R
2012-10-01
High-Resolution in situ observation of solidification experiments has become a powerful technique to improve the fundamental understanding of solidification processes of metals and alloys. In the present study, high-temperature laser-scanning confocal microscopy (HTLSCM) was utilized to observe and capture in situ solidification and phase transformations of alloys for subsequent post processing and analysis. Until now, this analysis has been very time consuming as frame-by-frame manual evaluation of propagating interfaces was used to determine the interface velocities. SolTrack has been developed using the commercial software package MATLAB and is designed to automatically detect, locate and track propagating interfaces during solidification and phase transformations as well as to calculate interfacial velocities. Different solidification phenomena have been recorded to demonstrate a wider spectrum of applications of this software. A validation, through comparison with manual evaluation, is included where the accuracy is shown to be very high. © 2012 The Authors Journal of Microscopy © 2012 Royal Microscopical Society.
Processing Infrared Images For Fire Management Applications
NASA Astrophysics Data System (ADS)
Warren, John R.; Pratt, William K.
1981-12-01
The USDA Forest Service has used airborne infrared systems for forest fire detection and mapping for many years. The transfer of the images from plane to ground and the transposition of fire spots and perimeters to maps has been performed manually. A new system has been developed which uses digital image processing, transmission, and storage. Interactive graphics, high resolution color display, calculations, and computer model compatibility are featured in the system. Images are acquired by an IR line scanner and converted to 1024 x 1024 x 8 bit frames for transmission to the ground at a 1.544 M bit rate over a 14.7 GHZ carrier. Individual frames are received and stored, then transferred to a solid state memory to refresh the display at a conventional 30 frames per second rate. Line length and area calculations, false color assignment, X-Y scaling, and image enhancement are available. Fire spread can be calculated for display and fire perimeters plotted on maps. The performance requirements, basic system, and image processing will be described.
NASA Astrophysics Data System (ADS)
Elahi, Sahar; Thrane, Lars; Rollins, Andrew M.; Jenkins, Michael W.
2017-02-01
Altered hemodynamics in developing embryonic hearts lead to congenital heart diseases, motivating close monitoring of blood flow over several stages of development. Doppler OCT can assess blood flow in tubular hearts, but the maximum velocity increases drastically during the period of cardiac cushion (valve precursors) formation. Therefore, the limited dynamic range of Doppler OCT velocity measurement makes it difficult to conduct longitudinal studies without phase wrapping at high velocities or loss of sensitivity to slow velocities. We have built a high-speed OCT system using an FDML laser (Optores GmbH, Germany) at a sweep rate of 1.68 MHz (axial resolution - 12 μm, sensitivity - 105 dB, phase stability - 17 mrad). The speed of this OCT system allows us to acquire high-density B-scans to obtain an extended velocity dynamic range without sacrificing the frame rate. The extended dynamic range within a frame is achieved by varying the A-scan interval at which the phase difference is found, enabling detection of velocities ranging from tens of microns per second to hundreds of mm per second. The extra lines in a frame can also be utilized to improve the structural and Doppler images via complex averaging. In structural images where presence of blood causes additional scattering, complex averaging helps retrieve features located deeper in the tissue. Moreover, high-density frames can be registered to 4D volumes to determine the orthogonal direction of flow and calculate shear stress. In conclusion, our high-speed OCT system will enable automated Doppler imaging of embryonic hearts in cohort studies.
NASA Astrophysics Data System (ADS)
Rzhanov, Y.; Mayer, L.; Fornari, D.; Shank, T.; Humphris, S.; Scheirer, D.; Kinsey, J.; Whitcomb, L.
2003-12-01
The Rosebud hydrothermal vent field was discovered in May 2002 in the Galapagos Rift near 86W during a series of Alvin dives and ABE autonomous vehicle surveys. Vertical-incidence digital imaging using a 3.1 Mpixel digital camera and strobe illumination from altitudes of 3-5m was carried out during the Alvin dives. A complete survey of the Rosebud vent site was carried out on Alvin Dive 3790. Submersible position was determined by post-cruise integration of 1.2 MHz bottom-lock Doppler sonar velocity data logged at 5Hz, integrated with heading and attitude data from a north-seeking fiber-optic gyroscope logged at 10Hz, and initialized with a surveyed-in long-baseline transponder navigation system providing geodetic position fixes at 15s intervals. The photo-mosaicing process consisted of three main stages: pre-processing, pair-wise image co-registration, and global alignment. Excellent image quality allowed us to avoid lens distortion correction, so images only underwent histogram equalization. Pair-wise co-registration of sequential frames was done partially automatically (where overlap exceeded 70 percent we employed a frequency-domain based technique), and partially manually (when overlap did not exceed 15 percent and manual feature extraction was the only way to find transformations relating the frames). Partial mosaics allowed us to determine which non-sequential frames had substantial overlap, and the corresponding transformations were found via feature extraction. Global alignment of the images consisted of construction of a sparse, nonlinear over-constrained system of equations reflecting positions of the frames in real-world coordinates. This system was solved using least squares, and the solution provided globally optimal positions of the frames in the overall mosaic. Over 700 images were mosaiced resulting in resolution of ~3 mm per pixel. The mosaiced area covers approximately 50 m x 60 m and clearly shows several biological zonations and distribution of lava flow morphologies, including what is interpreted as the contact between older lobate lava and the young sheet flow that hosts Rosebud vent communities. Recruitment of tubeworms, mussels, and clams is actively occurring at more than five locations oriented on a NE-SW trend where vent emissions occur through small cracks in the sheet flow. Large-scale views of seafloor hydrothermal vent sites, such as the one produced for Rosebud, are critical to properly understanding spatial relationships between hydrothermal biological communities, sites of focused and diffuse fluid flow, and the complex array of volcanic and tectonic features at mid-ocean ridge crests. These high-resolution perspectives are also critical to time-series studies where quantitative documentation of changes can be related to variations in hydrothermal, magmatic and tectonic processes.
High-Resolution Topography and its Implications for the Formation of Europa's Ridged Plains
NASA Astrophysics Data System (ADS)
Leonard, E. J.; Pappalardo, R. T.; Yin, A.; Patthoff, D. A.; Schenk, P.
2015-12-01
The Galileo Solid State Imager (SSI) recorded nine very high-resolution frames—eight at 12 m/pixel and one at 6 m/pixel—during the E12 flyby of Europa in Dec. 1997. To understand the implications for the small-scale structure and evolution of Europa, we mosaicked these frames (observations 12ESMOTTLE01 and 02, incidence ≈18°, emission ≈77°) into their regional context (part of observation 11ESREGMAP01, 220 m/pixel, incidence ≈74°, emission ≈23°). The topography data, which was created from the image mosaic overlaps, is sparse and segmented over the high-resolution images but connected by the underlying regional resolution topography. The high-resolution topography (24 m/pixel) is among the best for the current Europan dataset. From this dataset we ascertain the root mean square, or RMS, slope for some of the most common Europan surface features in a new region. We also employ a Fourier Transform method previously used on Ganymede and on other areas of Europa (Patel et al., 1999 JGR), to derive common wavelengths for the subunits of the ubiquitous ridged plains terrain. These results have important implications for differentiating between possible formation mechanisms—extensional tilt blocks (Pappalardo et al., 1995 JGR) or folds (Leonard et al., 2015 LPSC Abstract)—and for potential future missions. We continue this method for another high-resolution region taken in the E12 orbit, WEDGES01 and 02, with the specific goal of investigating how the variations in ridged plains morphologies relate across the surface of Europa.
NASA Astrophysics Data System (ADS)
Wiskin, James; Klock, John; Iuanow, Elaine; Borup, Dave T.; Terry, Robin; Malik, Bilal H.; Lenox, Mark
2017-03-01
There has been a great deal of research into ultrasound tomography for breast imaging over the past 35 years. Few successful attempts have been made to reconstruct high-resolution images using transmission ultrasound. To this end, advances have been made in 2D and 3D algorithms that utilize either time of arrival or full wave data to reconstruct images with high spatial and contrast resolution suitable for clinical interpretation. The highest resolution and quantitative accuracy result from inverse scattering applied to full wave data in 3D. However, this has been prohibitively computationally expensive, meaning that full inverse scattering ultrasound tomography has not been considered clinically viable. Here we show the results of applying a nonlinear inverse scattering algorithm to 3D data in a clinically useful time frame. This method yields Quantitative Transmission (QT) ultrasound images with high spatial and contrast resolution. We reconstruct sound speeds for various 2D and 3D phantoms and verify these values with independent measurements. The data are fully 3D as is the reconstruction algorithm, with no 2D approximations. We show that 2D reconstruction algorithms can introduce artifacts into the QT breast image which are avoided by using a full 3D algorithm and data. We show high resolution gross and microscopic anatomic correlations comparing cadaveric breast QT images with MRI to establish imaging capability and accuracy. Finally, we show reconstructions of data from volunteers, as well as an objective visual grading analysis to confirm clinical imaging capability and accuracy.
Ross, Sandy A; Rice, Clinton; Von Behren, Kristyn; Meyer, April; Alexander, Rachel; Murfin, Scott
2015-01-01
The purpose of this study was to establish intra-rater, intra-session, and inter-rater, reliability of sagittal plane hip, knee, and ankle angles with and without reflective markers using the GAITRite walkway and single video camera between student physical therapists and an experienced physical therapist. This study included thirty-two healthy participants age 20-59, stratified by age and gender. Participants performed three successful walks with and without markers applied to anatomical landmarks. GAITRite software was used to digitize sagittal hip, knee, and ankle angles at two phases of gait: (1) initial contact; and (2) mid-stance. Intra-rater reliability was more consistent for the experienced physical therapist, regardless of joint or phase of gait. Intra-session reliability was variable, the experienced physical therapist showed moderate to high reliability (intra-class correlation coefficient (ICC) = 0.50-0.89) and the student physical therapist showed very poor to high reliability (ICC = 0.07-0.85). Inter-rater reliability was highest during mid-stance at the knee with markers (ICC = 0.86) and lowest during mid-stance at the hip without markers (ICC = 0.25). Reliability of a single camera system, especially at the knee joint shows promise. Depending on the specific type of reliability, error can be attributed to the testers (e.g. lack of digitization practice and marker placement), participants (e.g. loose fitting clothing) and camera systems (e.g. frame rate and resolution). However, until the camera technology can be upgraded to a higher frame rate and resolution, and the software can be linked to the GAITRite walkway, the clinical utility for pre/post measures is limited.
NASA Astrophysics Data System (ADS)
Prabhu, David; Mehanna, Emile; Gargesha, Madhusudhana; Wen, Di; Brandt, Eric; van Ditzhuijzen, Nienke S.; Chamie, Daniel; Yamamoto, Hirosada; Fujino, Yusuke; Farmazilian, Ali; Patel, Jaymin; Costa, Marco; Bezerra, Hiram G.; Wilson, David L.
2016-03-01
High resolution, 100 frames/sec intravascular optical coherence tomography (IVOCT) can distinguish plaque types, but further validation is needed, especially for automated plaque characterization. We developed experimental and 3D registration methods, to provide validation of IVOCT pullback volumes using microscopic, brightfield and fluorescent cryoimage volumes, with optional, exactly registered cryo-histology. The innovation was a method to match an IVOCT pullback images, acquired in the catheter reference frame, to a true 3D cryo-image volume. Briefly, an 11-parameter, polynomial virtual catheter was initialized within the cryo-image volume, and perpendicular images were extracted, mimicking IVOCT image acquisition. Virtual catheter parameters were optimized to maximize cryo and IVOCT lumen overlap. Local minima were possible, but when we started within reasonable ranges, every one of 24 digital phantom cases converged to a good solution with a registration error of only +1.34+/-2.65μm (signed distance). Registration was applied to 10 ex-vivo cadaver coronary arteries (LADs), resulting in 10 registered cryo and IVOCT volumes yielding a total of 421 registered 2D-image pairs. Image overlays demonstrated high continuity between vascular and plaque features. Bland- Altman analysis comparing cryo and IVOCT lumen area, showed mean and standard deviation of differences as 0.01+/-0.43 mm2. DICE coefficients were 0.91+/-0.04. Finally, visual assessment on 20 representative cases with easily identifiable features suggested registration accuracy within one frame of IVOCT (+/-200μm), eliminating significant misinterpretations introduced by 1mm errors in the literature. The method will provide 3D data for training of IVOCT plaque algorithms and can be used for validation of other intravascular imaging modalities.
Wu, Jianglai; Tang, Anson H. L.; Mok, Aaron T. Y.; Yan, Wenwei; Chan, Godfrey C. F.; Wong, Kenneth K. Y.; Tsia, Kevin K.
2017-01-01
Apart from the spatial resolution enhancement, scaling of temporal resolution, equivalently the imaging throughput, of fluorescence microscopy is of equal importance in advancing cell biology and clinical diagnostics. Yet, this attribute has mostly been overlooked because of the inherent speed limitation of existing imaging strategies. To address the challenge, we employ an all-optical laser-scanning mechanism, enabled by an array of reconfigurable spatiotemporally-encoded virtual sources, to demonstrate ultrafast fluorescence microscopy at line-scan rate as high as 8 MHz. We show that this technique enables high-throughput single-cell microfluidic fluorescence imaging at 75,000 cells/second and high-speed cellular 2D dynamical imaging at 3,000 frames per second, outperforming the state-of-the-art high-speed cameras and the gold-standard laser scanning strategies. Together with its wide compatibility to the existing imaging modalities, this technology could empower new forms of high-throughput and high-speed biological fluorescence microscopy that was once challenged. PMID:28966855
High-resolution clustered pinhole (131)Iodine SPECT imaging in mice.
van der Have, Frans; Ivashchenko, Oleksandra; Goorden, Marlies C; Ramakers, Ruud M; Beekman, Freek J
2016-08-01
High-resolution pre-clinical (131)I SPECT can facilitate development of new radioiodine therapies for cancer. To this end, it is important to limit resolution-degrading effects of pinhole edge penetration by the high-energy γ-photons of iodine. Here we introduce, optimize and validate (131)I SPECT performed with a dedicated high-energy clustered multi-pinhole collimator. A SPECT-CT system (VECTor/CT) with stationary gamma-detectors was equipped with a tungsten collimator with clustered pinholes. Images were reconstructed with pixel-based OSEM, using a dedicated (131)I system matrix that models the distance- and energy-dependent resolution and sensitivity of each pinhole, as well as the intrinsic detector blurring and variable depth of interaction in the detector. The system performance was characterized with phantoms and in vivo static and dynamic (131)I-NaI scans of mice. Reconstructed image resolution reached 0.6mm, while quantitative accuracy measured with a (131)I filled syringe reaches an accuracy of +3.6±3.5% of the gold standard value. In vivo mice scans illustrated a clear shape of the thyroid and biodistribution of (131)I within the animal. Pharmacokinetics of (131)I was assessed with 15-s time frames from the sequence of dynamic images and time-activity curves of (131)I-NaI. High-resolution quantitative and fast dynamic (131)I SPECT in mice is possible by means of a high-energy collimator and optimized system modeling. This enables analysis of (131)I uptake even within small organs in mice, which can be highly valuable for development and optimization of targeted cancer therapies. Copyright © 2016 Elsevier Inc. All rights reserved.
Droplet Image Super Resolution Based on Sparse Representation and Kernel Regression
NASA Astrophysics Data System (ADS)
Zou, Zhenzhen; Luo, Xinghong; Yu, Qiang
2018-02-01
Microgravity and containerless conditions, which are produced via electrostatic levitation combined with a drop tube, are important when studying the intrinsic properties of new metastable materials. Generally, temperature and image sensors can be used to measure the changes of sample temperature, morphology and volume. Then, the specific heat, surface tension, viscosity changes and sample density can be obtained. Considering that the falling speed of the material sample droplet is approximately 31.3 m/s when it reaches the bottom of a 50-meter-high drop tube, a high-speed camera with a collection rate of up to 106 frames/s is required to image the falling droplet. However, at the high-speed mode, very few pixels, approximately 48-120, will be obtained in each exposure time, which results in low image quality. Super-resolution image reconstruction is an algorithm that provides finer details than the sampling grid of a given imaging device by increasing the number of pixels per unit area in the image. In this work, we demonstrate the application of single image-resolution reconstruction in the microgravity and electrostatic levitation for the first time. Here, using the image super-resolution method based on sparse representation, a low-resolution droplet image can be reconstructed. Employed Yang's related dictionary model, high- and low-resolution image patches were combined with dictionary training, and high- and low-resolution-related dictionaries were obtained. The online double-sparse dictionary training algorithm was used in the study of related dictionaries and overcome the shortcomings of the traditional training algorithm with small image patch. During the stage of image reconstruction, the algorithm of kernel regression is added, which effectively overcomes the shortcomings of the Yang image's edge blurs.
Droplet Image Super Resolution Based on Sparse Representation and Kernel Regression
NASA Astrophysics Data System (ADS)
Zou, Zhenzhen; Luo, Xinghong; Yu, Qiang
2018-05-01
Microgravity and containerless conditions, which are produced via electrostatic levitation combined with a drop tube, are important when studying the intrinsic properties of new metastable materials. Generally, temperature and image sensors can be used to measure the changes of sample temperature, morphology and volume. Then, the specific heat, surface tension, viscosity changes and sample density can be obtained. Considering that the falling speed of the material sample droplet is approximately 31.3 m/s when it reaches the bottom of a 50-meter-high drop tube, a high-speed camera with a collection rate of up to 106 frames/s is required to image the falling droplet. However, at the high-speed mode, very few pixels, approximately 48-120, will be obtained in each exposure time, which results in low image quality. Super-resolution image reconstruction is an algorithm that provides finer details than the sampling grid of a given imaging device by increasing the number of pixels per unit area in the image. In this work, we demonstrate the application of single image-resolution reconstruction in the microgravity and electrostatic levitation for the first time. Here, using the image super-resolution method based on sparse representation, a low-resolution droplet image can be reconstructed. Employed Yang's related dictionary model, high- and low-resolution image patches were combined with dictionary training, and high- and low-resolution-related dictionaries were obtained. The online double-sparse dictionary training algorithm was used in the study of related dictionaries and overcome the shortcomings of the traditional training algorithm with small image patch. During the stage of image reconstruction, the algorithm of kernel regression is added, which effectively overcomes the shortcomings of the Yang image's edge blurs.
Murrie, Rhiannon P; Morgan, Kaye S; Maksimenko, Anton; Fouras, Andreas; Paganin, David M; Hall, Chris; Siu, Karen K W; Parsons, David W; Donnelley, Martin
2015-07-01
The high flux and coherence produced at long synchrotron beamlines makes them well suited to performing phase-contrast X-ray imaging of the airways and lungs of live small animals. Here, findings of the first live-animal imaging on the Imaging and Medical Beamline (IMBL) at the Australian Synchrotron are reported, demonstrating the feasibility of performing dynamic lung motion measurement and high-resolution micro-tomography. Live anaesthetized mice were imaged using 30 keV monochromatic X-rays at a range of sample-to-detector propagation distances. A frame rate of 100 frames s(-1) allowed lung motion to be determined using X-ray velocimetry. A separate group of humanely killed mice and rats were imaged by computed tomography at high resolution. Images were reconstructed and rendered to demonstrate the capacity for detailed, user-directed display of relevant respiratory anatomy. The ability to perform X-ray velocimetry on live mice at the IMBL was successfully demonstrated. High-quality renderings of the head and lungs visualized both large structures and fine details of the nasal and respiratory anatomy. The effect of sample-to-detector propagation distance on contrast and resolution was also investigated, demonstrating that soft tissue contrast increases, and resolution decreases, with increasing propagation distance. This new capability to perform live-animal imaging and high-resolution micro-tomography at the IMBL enhances the capability for investigation of respiratory diseases and the acceleration of treatment development in Australia.
NASA Astrophysics Data System (ADS)
Jünger, Felix; Olshausen, Philipp V.; Rohrbach, Alexander
2016-07-01
Living cells are highly dynamic systems with cellular structures being often below the optical resolution limit. Super-resolution microscopes, usually based on fluorescence cell labelling, are usually too slow to resolve small, dynamic structures. We present a label-free microscopy technique, which can generate thousands of super-resolved, high contrast images at a frame rate of 100 Hertz and without any post-processing. The technique is based on oblique sample illumination with coherent light, an approach believed to be not applicable in life sciences because of too many interference artefacts. However, by circulating an incident laser beam by 360° during one image acquisition, relevant image information is amplified. By combining total internal reflection illumination with dark-field detection, structures as small as 150 nm become separable through local destructive interferences. The technique images local changes in refractive index through scattered laser light and is applied to living mouse macrophages and helical bacteria revealing unexpected dynamic processes.
Jünger, Felix; Olshausen, Philipp v.; Rohrbach, Alexander
2016-01-01
Living cells are highly dynamic systems with cellular structures being often below the optical resolution limit. Super-resolution microscopes, usually based on fluorescence cell labelling, are usually too slow to resolve small, dynamic structures. We present a label-free microscopy technique, which can generate thousands of super-resolved, high contrast images at a frame rate of 100 Hertz and without any post-processing. The technique is based on oblique sample illumination with coherent light, an approach believed to be not applicable in life sciences because of too many interference artefacts. However, by circulating an incident laser beam by 360° during one image acquisition, relevant image information is amplified. By combining total internal reflection illumination with dark-field detection, structures as small as 150 nm become separable through local destructive interferences. The technique images local changes in refractive index through scattered laser light and is applied to living mouse macrophages and helical bacteria revealing unexpected dynamic processes. PMID:27465033
NASA Astrophysics Data System (ADS)
Luquet, Ph.; Chikouche, A.; Benbouzid, A. B.; Arnoux, J. J.; Chinal, E.; Massol, C.; Rouchit, P.; De Zotti, S.
2017-11-01
EADS Astrium is currently developing a new product line of compact and versatile instruments for high resolution missions in Earth Observation. First version has been developed in the frame of the ALSAT-2 contract awarded by the Algerian Space Agency (ASAL) to EADS Astrium. The Silicon Carbide Korsch-type telescope coupled with a multilines detector array offers a 2.5 m GSD in PAN band at Nadir @ 680 km altitude (10 m GSD in the four multispectral bands) with a 17.5 km swath width. This compact camera - 340 (W) x 460 (L) x 510 (H) mm3, 13 kg - is embarked on a Myriade-type small platform. The electronics unit accommodates video, housekeeping, and thermal control functions and also a 64 Gbit mass memory. Two satellites are developed; the first one is planned to be launched on mid 2009. Several other versions of the instrument have already been defined with enhanced resolution or/and larger field of view.
Spatiotemporal focusing-based widefield multiphoton microscopy for fast optical sectioning.
Cheng, Li-Chung; Chang, Chia-Yuan; Lin, Chun-Yu; Cho, Keng-Chi; Yen, Wei-Chung; Chang, Nan-Shan; Xu, Chris; Dong, Chen Yuan; Chen, Shean-Jen
2012-04-09
In this study, a microscope based on spatiotemporal focusing offering widefield multiphoton excitation has been developed to provide fast optical sectioning images. Key features of this microscope are the integrations of a 10 kHz repetition rate ultrafast amplifier featuring high instantaneous peak power (maximum 400 μJ/pulse at a 90 fs pulse width) and a TE-cooled, ultra-sensitive photon detecting, electron multiplying charge-coupled camera into a spatiotemporal focusing microscope. This configuration can produce multiphoton images with an excitation area larger than 200 × 100 μm² at a frame rate greater than 100 Hz (current maximum of 200 Hz). Brownian motions of fluorescent microbeads as small as 0.5 μm were observed in real-time with a lateral spatial resolution of less than 0.5 μm and an axial resolution of approximately 3.5 μm. Furthermore, second harmonic images of chicken tendons demonstrate that the developed widefield multiphoton microscope can provide high resolution z-sectioning for bioimaging.
NASA Astrophysics Data System (ADS)
Sarantites, D. G.; Reviol, W.; Elson, J. M.; Kinnison, J. E.; Izzo, C. J.; Manfredi, J.; Liu, J.; Jung, H. S.; Goerres, J.
2015-08-01
A high-efficiency, forward-hemisphere detector system for light charged particles and low-Z heavy ions, as obtained in an accelerator experiment, is described. It consists of four 8×8 pixel multianode photomultiplier tubes with 2.2-mm thick CsI(Tl) and 12 -μm thick fast-plastic scintillation detectors. Its phoswich structure allows individual Z resolution for 1H, 4He, 7Li, 4He+4He, 9Be, 11B, 12C, and 14N ions, which are target-like fragments detected in strongly inverse kinematics. The device design has been optimized for use with a 4π γ-ray array, and the main applications are transfer reactions and Coulomb excitation. A high-angular resolution for the detection of the target-like fragments is achieved which permits angular distributions to be measured in the rest frame of the projectile-like fragment with a resolution of ~ 2 °.
Fabrication update on critical-angle transmission gratings for soft x-ray grating spectrometers
NASA Astrophysics Data System (ADS)
Heilmann, Ralf K.; Bruccoleri, Alex; Mukherjee, Pran; Yam, Jonathan; Schattenburg, Mark L.
2011-09-01
Diffraction grating-based, wavelength dispersive high-resolution soft x-ray spectroscopy of celestial sources promises to reveal crucial data for the study of the Warm-Hot Intergalactic Medium, the Interstellar Medium, warm absorption and outflows in Active Galactic Nuclei, coronal emission from stars, and other areas of interest to the astrophysics community. Our recently developed critical-angle transmission (CAT) gratings combine the advantages of the Chandra high and medium energy transmission gratings (low mass, high tolerance of misalignments and figure errors, polarization insensitivity) with those of blazed reflection gratings (high broad band diffraction efficiency, high resolution through use of higher diffraction orders) such as the ones on XMM-Newton. Extensive instrument and system configuration studies have shown that a CAT grating-based spectrometer is an outstanding instrument capable of delivering resolving power on the order of 5,000 and high effective area, even with a telescope point-spread function on the order of many arc-seconds. We have fabricated freestanding, ultra-high aspect-ratio CAT grating bars from silicon-on-insulator wafers using both wet and dry etch processes. The 200 nm-period grating bars are supported by an integrated Level 1 support mesh, and a coarser external Level 2 support mesh. The resulting grating membrane is mounted to a frame, resulting in a grating facet. Many such facets comprise a grating array that provides light-weight coverage of large-area telescope apertures. Here we present fabrication results on the integration of CAT gratings and the different high-throughput support mesh levels and on membrane-frame bonding. We also summarize recent x-ray data analysis of 3 and 6 micron deep wet-etched CAT grating prototypes.
Bowen, Spencer L.; Byars, Larry G.; Michel, Christian J.; Chonde, Daniel B.; Catana, Ciprian
2014-01-01
Kinetic parameters estimated from dynamic 18F-fluorodeoxyglucose PET acquisitions have been used frequently to assess brain function in humans. Neglecting partial volume correction (PVC) for a dynamic series has been shown to produce significant bias in model estimates. Accurate PVC requires a space-variant model describing the reconstructed image spatial point spread function (PSF) that accounts for resolution limitations, including non-uniformities across the field of view due to the parallax effect. For OSEM, image resolution convergence is local and influenced significantly by the number of iterations, the count density, and background-to-target ratio. As both count density and background-to-target values for a brain structure can change during a dynamic scan, the local image resolution may also concurrently vary. When PVC is applied post-reconstruction the kinetic parameter estimates may be biased when neglecting the frame-dependent resolution. We explored the influence of the PVC method and implementation on kinetic parameters estimated by fitting 18F-fluorodeoxyglucose dynamic data acquired on a dedicated brain PET scanner and reconstructed with and without PSF modelling in the OSEM algorithm. The performance of several PVC algorithms was quantified with a phantom experiment, an anthropomorphic Monte Carlo simulation, and a patient scan. Using the last frame reconstructed image only for regional spread function (RSF) generation, as opposed to computing RSFs for each frame independently, and applying perturbation GTM PVC with PSF based OSEM produced the lowest magnitude bias kinetic parameter estimates in most instances, although at the cost of increased noise compared to the PVC methods utilizing conventional OSEM. Use of the last frame RSFs for PVC with no PSF modelling in the OSEM algorithm produced the lowest bias in CMRGlc estimates, although by less than 5% in most cases compared to the other PVC methods. The results indicate that the PVC implementation and choice of PSF modelling in the reconstruction can significantly impact model parameters. PMID:24052021
SNR improvement for hyperspectral application using frame and pixel binning
NASA Astrophysics Data System (ADS)
Rehman, Sami Ur; Kumar, Ankush; Banerjee, Arup
2016-05-01
Hyperspectral imaging spectrometer systems are increasingly being used in the field of remote sensing for variety of civilian and military applications. The ability of such instruments in discriminating finer spectral features along with improved spatial and radiometric performance have made such instruments a powerful tool in the field of remote sensing. Design and development of spaceborne hyper spectral imaging spectrometers poses lot of technological challenges in terms of optics, dispersion element, detectors, electronics and mechanical systems. The main factors that define the type of detectors are the spectral region, SNR, dynamic range, pixel size, number of pixels, frame rate, operating temperature etc. Detectors with higher quantum efficiency and higher well depth are the preferred choice for such applications. CCD based Si detectors serves the requirement of high well depth for VNIR band spectrometers but suffers from smear. Smear can be controlled by using CMOS detectors. Si CMOS detectors with large format arrays are available. These detectors generally have smaller pitch and low well depth. Binning technique can be used with available CMOS detectors to meet the large swath, higher resolution and high SNR requirements. Availability of larger dwell time of satellite can be used to bin multiple frames to increase the signal collection even with lesser well depth detectors and ultimately increase the SNR. Lab measurements reveal that SNR improvement by frame binning is more in comparison to pixel binning. Effect of pixel binning as compared to the frame binning will be discussed and degradation of SNR as compared to theoretical value for pixel binning will be analyzed.
Multimodality optical imaging of embryonic heart microstructure
Yelin, Ronit; Yelin, Dvir; Oh, Wang-Yuhl; Yun, Seok H.; Boudoux, Caroline; Vakoc, Benjamin J.; Bouma, Brett E.; Tearney, Guillermo J.
2009-01-01
Study of developmental heart defects requires the visualization of the microstructure and function of the embryonic myocardium, ideally with minimal alterations to the specimen. We demonstrate multiple endogenous contrast optical techniques for imaging the Xenopus laevis tadpole heart. Each technique provides distinct and complementary imaging capabilities, including: 1. 3-D coherence microscopy with subcellular (1 to 2 µm) resolution in fixed embryos, 2. real-time reflectance confocal microscopy with large penetration depth in vivo, and 3. ultra-high speed (up to 900 frames per second) that enables real-time 4-D high resolution imaging in vivo. These imaging modalities can provide a comprehensive picture of the morphologic and dynamic phenotype of the embryonic heart. The potential of endogenous-contrast optical microscopy is demonstrated for investigation of the teratogenic effects of ethanol. Microstructural abnormalities associated with high levels of ethanol exposure are observed, including compromised heart looping and loss of ventricular trabecular mass. PMID:18163837
Multimodality optical imaging of embryonic heart microstructure.
Yelin, Ronit; Yelin, Dvir; Oh, Wang-Yuhl; Yun, Seok H; Boudoux, Caroline; Vakoc, Benjamin J; Bouma, Brett E; Tearney, Guillermo J
2007-01-01
Study of developmental heart defects requires the visualization of the microstructure and function of the embryonic myocardium, ideally with minimal alterations to the specimen. We demonstrate multiple endogenous contrast optical techniques for imaging the Xenopus laevis tadpole heart. Each technique provides distinct and complementary imaging capabilities, including: 1. 3-D coherence microscopy with subcellular (1 to 2 microm) resolution in fixed embryos, 2. real-time reflectance confocal microscopy with large penetration depth in vivo, and 3. ultra-high speed (up to 900 frames per second) that enables real-time 4-D high resolution imaging in vivo. These imaging modalities can provide a comprehensive picture of the morphologic and dynamic phenotype of the embryonic heart. The potential of endogenous-contrast optical microscopy is demonstrated for investigation of the teratogenic effects of ethanol. Microstructural abnormalities associated with high levels of ethanol exposure are observed, including compromised heart looping and loss of ventricular trabecular mass.
Cell signaling, post-translational protein modifications and NMR spectroscopy
Theillet, Francois-Xavier; Smet-Nocca, Caroline; Liokatis, Stamatios; Thongwichian, Rossukon; Kosten, Jonas; Yoon, Mi-Kyung; Kriwacki, Richard W.; Landrieu, Isabelle; Lippens, Guy
2016-01-01
Post-translationally modified proteins make up the majority of the proteome and establish, to a large part, the impressive level of functional diversity in higher, multi-cellular organisms. Most eukaryotic post-translational protein modifications (PTMs) denote reversible, covalent additions of small chemical entities such as phosphate-, acyl-, alkyl- and glycosyl-groups onto selected subsets of modifiable amino acids. In turn, these modifications induce highly specific changes in the chemical environments of individual protein residues, which are readily detected by high-resolution NMR spectroscopy. In the following, we provide a concise compendium of NMR characteristics of the main types of eukaryotic PTMs: serine, threonine, tyrosine and histidine phosphorylation, lysine acetylation, lysine and arginine methylation, and serine, threonine O-glycosylation. We further delineate the previously uncharacterized NMR properties of lysine propionylation, butyrylation, succinylation, malonylation and crotonylation, which, altogether, define an initial reference frame for comprehensive PTM studies by high-resolution NMR spectroscopy. PMID:23011410
High-resolution neutron powder diffractometer SPODI at research reactor FRM II
NASA Astrophysics Data System (ADS)
Hoelzel, M.; Senyshyn, A.; Juenke, N.; Boysen, H.; Schmahl, W.; Fuess, H.
2012-03-01
SPODI is a high-resolution thermal neutron diffractometer at the research reactor Heinz Maier-Leibnitz (FRM II) especially dedicated to structural studies of complex systems. Unique features like a very large monochromator take-off angle of 155° and a 5 m monochromator-sample distance in its standard configuration achieve both high-resolution and a good profile shape for a broad scattering angle range. Two dimensional data are collected by an array of 80 vertical position sensitive 3He detectors. SPODI is well suited for studies of complex structural and magnetic order and disorder phenomena at non-ambient conditions. In addition to standard sample environment facilities (cryostats, furnaces, magnet) specific devices (rotatable load frame, cell for electric fields, multichannel potentiostat) were developed. Thus the characterisation of functional materials at in-operando conditions can be achieved. In this contribution the details of the design and present performance of the instrument are reported along with its specifications. A new concept for data reduction using a 2 θ dependent variable height for the intensity integration along the Debye-Scherrer lines is introduced.
Towards a real-time wide area motion imagery system
NASA Astrophysics Data System (ADS)
Young, R. I.; Foulkes, S. B.
2015-10-01
It is becoming increasingly important in both the defence and security domains to conduct persistent wide area surveillance (PWAS) of large populations of targets. Wide Area Motion Imagery (WAMI) is a key technique for achieving this wide area surveillance. The recent development of multi-million pixel sensors has provided sensors with wide field of view replete with sufficient resolution for detection and tracking of objects of interest to be achieved across these extended areas of interest. WAMI sensors simultaneously provide high spatial and temporal resolutions, giving extreme pixel counts over large geographical areas. The high temporal resolution is required to enable effective tracking of targets. The provision of wide area coverage with high frame rates generates data deluge issues; these are especially profound if the sensor is mounted on an airborne platform, with finite data-link bandwidth and processing power that is constrained by size, weight and power (SWAP) limitations. These issues manifest themselves either as bottlenecks in the transmission of the imagery off-board or as latency in the time taken to analyse the data due to limited computational processing power.
Rapid Target Detection in High Resolution Remote Sensing Images Using Yolo Model
NASA Astrophysics Data System (ADS)
Wu, Z.; Chen, X.; Gao, Y.; Li, Y.
2018-04-01
Object detection in high resolution remote sensing images is a fundamental and challenging problem in the field of remote sensing imagery analysis for civil and military application due to the complex neighboring environments, which can cause the recognition algorithms to mistake irrelevant ground objects for target objects. Deep Convolution Neural Network(DCNN) is the hotspot in object detection for its powerful ability of feature extraction and has achieved state-of-the-art results in Computer Vision. Common pipeline of object detection based on DCNN consists of region proposal, CNN feature extraction, region classification and post processing. YOLO model frames object detection as a regression problem, using a single CNN predicts bounding boxes and class probabilities in an end-to-end way and make the predict faster. In this paper, a YOLO based model is used for object detection in high resolution sensing images. The experiments on NWPU VHR-10 dataset and our airport/airplane dataset gain from GoogleEarth show that, compare with the common pipeline, the proposed model speeds up the detection process and have good accuracy.
A restraint-free small animal SPECT imaging system with motion tracking
DOE Office of Scientific and Technical Information (OSTI.GOV)
Weisenberger, A.G.; Gleason, S.S.; Goddard, J.
2005-06-01
We report on an approach toward the development of a high-resolution single photon emission computed tomography (SPECT) system to image the biodistribution of radiolabeled tracers such as Tc-99m and I-125 in unrestrained/unanesthetized mice. An infrared (IR)-based position tracking apparatus has been developed and integrated into a SPECT gantry. The tracking system is designed to measure the spatial position of a mouse's head at a rate of 10-15 frames per second with submillimeter accuracy. The high-resolution, gamma imaging detectors are based on pixellated NaI(Tl) crystal scintillator arrays, position-sensitive photomultiplier tubes, and novel readout circuitry requiring fewer analog-digital converter (ADC) channels whilemore » retaining high spatial resolution. Two SPECT gamma camera detector heads based upon position-sensitive photomultiplier tubes have been built and installed onto the gantry. The IR landmark-based pose measurement and tracking system is under development to provide animal position data during a SPECT scan. The animal position and orientation data acquired by the tracking system will be used for motion correction during the tomographic image reconstruction.« less
A High-Speed Spectroscopy System for Observing Lightning and Transient Luminous Events
NASA Astrophysics Data System (ADS)
Boggs, L.; Liu, N.; Austin, M.; Aguirre, F.; Tilles, J.; Nag, A.; Lazarus, S. M.; Rassoul, H.
2017-12-01
Here we present a high-speed spectroscopy system that can be used to record atmospheric electrical discharges, including lightning and transient luminous events. The system consists of a Phantom V1210 high-speed camera, a Volume Phase Holographic (VPH) grism, an optional optical slit, and lenses. The spectrograph has the capability to record videos at speeds of 200,000 frames per second and has an effective wavelength band of 550-775 nm for the first order spectra. When the slit is used, the system has a spectral resolution of about 0.25 nm per pixel. We have constructed a durable enclosure made of heavy duty aluminum to house the high-speed spectrograph. It has two fans for continuous air flow and a removable tray to mount the spectrograph components. In addition, a Watec video camera (30 frames per second) is attached to the top of the enclosure to provide a scene view. A heavy duty Pelco pan/tilt motor is used to position the enclosure and can be controlled remotely through a Rasperry Pi computer. An observation campaign has been conducted during the summer and fall of 2017 at the Florida Institute of Technology. Several close cloud-to-ground discharges were recorded at 57,000 frames per second. The spectrum of a downward stepped negative leader and a positive cloud-to-ground return stroke will be reported on.
A hardware architecture for real-time shadow removal in high-contrast video
NASA Astrophysics Data System (ADS)
Verdugo, Pablo; Pezoa, Jorge E.; Figueroa, Miguel
2017-09-01
Broadcasting an outdoor sports event at daytime is a challenging task due to the high contrast that exists between areas in the shadow and light conditions within the same scene. Commercial cameras typically do not handle the high dynamic range of such scenes in a proper manner, resulting in broadcast streams with very little shadow detail. We propose a hardware architecture for real-time shadow removal in high-resolution video, which reduces the shadow effect and simultaneously improves shadow details. The algorithm operates only on the shadow portions of each video frame, thus improving the results and producing more realistic images than algorithms that operate on the entire frame, such as simplified Retinex and histogram shifting. The architecture receives an input in the RGB color space, transforms it into the YIQ space, and uses color information from both spaces to produce a mask of the shadow areas present in the image. The mask is then filtered using a connected components algorithm to eliminate false positives and negatives. The hardware uses pixel information at the edges of the mask to estimate the illumination ratio between light and shadow in the image, which is then used to correct the shadow area. Our prototype implementation simultaneously processes up to 7 video streams of 1920×1080 pixels at 60 frames per second on a Xilinx Kintex-7 XC7K325T FPGA.
Investigations of Martian history
NASA Technical Reports Server (NTRS)
Hartmann, W. K.
1976-01-01
Geologic and stratigraphic analyses of Martian channels were accomplished using Mariner frames of high resolution. Crater counts were made to determine which forms had the least relative age. Results indicate that major channel and chaotic systems were relatively young, and that Mars experienced periods of enhanced erosive activity during a period of early dense atmospheric activity with rain. The problem of absolute age determination is discussed and geomorphological studies of selected Local Martian Regions are presented.
Second-harmonic generation microscopy of tooth
NASA Astrophysics Data System (ADS)
Kao, Fu-Jen; Wang, Yung-Shun; Huang, Mao-Kuo; Huang, Sheng-Lung; Cheng, Ping C.
2000-07-01
In this study, we have developed a high performance microscopic system to perform second-harmonic (SH)imaging on a tooth. The high sensitivity of the system allows an acquisition rate of 300 seconds/frame with a resolution at 512x512 pixels. The surface SH signal generated from the tooth is also carefully verified through micro-spectroscopy, polarization rotation, and wavelength tuning. In this way, we can ensure the authenticity of the signal. The enamel that encapsulates the dentine is known to possess highly ordered structures. The anisotrophy of the structure is revealed in the microscopic SH images of the tooth sample.
Digital cinema system using JPEG2000 movie of 8-million pixel resolution
NASA Astrophysics Data System (ADS)
Fujii, Tatsuya; Nomura, Mitsuru; Shirai, Daisuke; Yamaguchi, Takahiro; Fujii, Tetsuro; Ono, Sadayasu
2003-05-01
We have developed a prototype digital cinema system that can store, transmit and display extra high quality movies of 8-million pixel resolution, using JPEG2000 coding algorithm. The image quality is 4 times better than HDTV in resolution, and enables us to replace conventional films with digital cinema archives. Using wide-area optical gigabit IP networks, cinema contents are distributed and played back as a video-on-demand (VoD) system. The system consists of three main devices, a video server, a real-time JPEG2000 decoder, and a large-venue LCD projector. All digital movie data are compressed by JPEG2000 and stored in advance. The coded streams of 300~500 Mbps can be continuously transmitted from the PC server using TCP/IP. The decoder can perform the real-time decompression at 24/48 frames per second, using 120 parallel JPEG2000 processing elements. The received streams are expanded into 4.5Gbps raw video signals. The prototype LCD projector uses 3 pieces of 3840×2048 pixel reflective LCD panels (D-ILA) to show RGB 30-bit color movies fed by the decoder. The brightness exceeds 3000 ANSI lumens for a 300-inch screen. The refresh rate is chosen to 96Hz to thoroughly eliminate flickers, while preserving compatibility to cinema movies of 24 frames per second.
NASA Technical Reports Server (NTRS)
Uccellini, L. W.; Kocin, P. J.
1981-01-01
An analysis of a tornado outbreak in Wichita Falls, Texas was analyzed. The coupling of upper and lower tropospheric jet streaks, leading to severe storm outbreaks is illustrated. The high resolution SESAME data sets indicate that mass and momentum adjustments which couple upper and lower tropospheric jets occur within a 3 to 6 hr time frame over a 100 to 500 km domain, and establish the role of isallobaric forcing in the storm development. It is suggested that the output rate of data from the existing 12 hr network be increased to provide better temporal resolution of wind, mass and moisture data.
Snorkelling between the stars: submarine methods for astronomical observations.
NASA Astrophysics Data System (ADS)
Velasco, S.; Quevedo, E.; Font, J.; Oscoz, A.; López, R. L.; Puga, M.; Rebolo, R.; Hernáandez Brito, J.; Llinas, O.; Marrero Callico, G.; Sarmiento, R.
2017-03-01
Trying to reach diffraction-limited astronomical observations from ground-based telescopes is very challenging due to the atmospheric effects contributing to a general blurring of the images. However, astronomy is not the only science facing turbulence problems; obtaining quality images of the undersea world is as ambitious as it is on the sky. One of the solutions contemplated to reach high-resolution images is the use of multiple frames of the same target, known as fusion super-resolution (Quevedo et al. 2015), which is the principle for Lucky Imaging (Velasco et al. 2016). Here we present the successful result of joining efforts between the undersea and the astronomical research done at the Canary Islands.
NASA Astrophysics Data System (ADS)
Poeggel, Sven; Tosi, Daniele; Duraibabu, Dineshbabu; Sannino, Simone; Lupoli, Laura; Ippolito, Juliet; Fusco, Fernando; Mirone, Vincenzo; Leen, Gabriel; Lewis, Elfed
2014-05-01
The all-glass optical fibre pressure and temperature sensor (OFPTS), present here is a combination of an extrinsic Fabry Perot Interferometer (EFPI) and an fiber Bragg gratings (FBG), which allows a simultaneously measurement of both pressure and temperature. Thermal effects experienced by the EFPI can be compensated by using the FBG. The sensor achieved a pressure measurement resolution of 0.1mmHg with a frame-rate of 100Hz and a low drift rate of < 1 mmHg/hour drift. The sensor has been evaluated using a cardiovascular simulator and additionally has been evaluated in-vivo in a urodynamics application under medical supervision.
Abdellah, Marwan; Eldeib, Ayman; Owis, Mohamed I
2015-01-01
This paper features an advanced implementation of the X-ray rendering algorithm that harnesses the giant computing power of the current commodity graphics processors to accelerate the generation of high resolution digitally reconstructed radiographs (DRRs). The presented pipeline exploits the latest features of NVIDIA Graphics Processing Unit (GPU) architectures, mainly bindless texture objects and dynamic parallelism. The rendering throughput is substantially improved by exploiting the interoperability mechanisms between CUDA and OpenGL. The benchmarks of our optimized rendering pipeline reflect its capability of generating DRRs with resolutions of 2048(2) and 4096(2) at interactive and semi interactive frame-rates using an NVIDIA GeForce 970 GTX device.
MEMS resonant load cells for micro-mechanical test frames: feasibility study and optimal design
NASA Astrophysics Data System (ADS)
Torrents, A.; Azgin, K.; Godfrey, S. W.; Topalli, E. S.; Akin, T.; Valdevit, L.
2010-12-01
This paper presents the design, optimization and manufacturing of a novel micro-fabricated load cell based on a double-ended tuning fork. The device geometry and operating voltages are optimized for maximum force resolution and range, subject to a number of manufacturing and electromechanical constraints. All optimizations are enabled by analytical modeling (verified by selected finite elements analyses) coupled with an efficient C++ code based on the particle swarm optimization algorithm. This assessment indicates that force resolutions of ~0.5-10 nN are feasible in vacuum (~1-50 mTorr), with force ranges as large as 1 N. Importantly, the optimal design for vacuum operation is independent of the desired range, ensuring versatility. Experimental verifications on a sub-optimal device fabricated using silicon-on-glass technology demonstrate a resolution of ~23 nN at a vacuum level of ~50 mTorr. The device demonstrated in this article will be integrated in a hybrid micro-mechanical test frame for unprecedented combinations of force resolution and range, displacement resolution and range, optical (or SEM) access to the sample, versatility and cost.
Tight-frame based iterative image reconstruction for spectral breast CT
Zhao, Bo; Gao, Hao; Ding, Huanjun; Molloi, Sabee
2013-01-01
Purpose: To investigate tight-frame based iterative reconstruction (TFIR) technique for spectral breast computed tomography (CT) using fewer projections while achieving greater image quality. Methods: The experimental data were acquired with a fan-beam breast CT system based on a cadmium zinc telluride photon-counting detector. The images were reconstructed with a varying number of projections using the TFIR and filtered backprojection (FBP) techniques. The image quality between these two techniques was evaluated. The image's spatial resolution was evaluated using a high-resolution phantom, and the contrast to noise ratio (CNR) was evaluated using a postmortem breast sample. The postmortem breast samples were decomposed into water, lipid, and protein contents based on images reconstructed from TFIR with 204 projections and FBP with 614 projections. The volumetric fractions of water, lipid, and protein from the image-based measurements in both TFIR and FBP were compared to the chemical analysis. Results: The spatial resolution and CNR were comparable for the images reconstructed by TFIR with 204 projections and FBP with 614 projections. Both reconstruction techniques provided accurate quantification of water, lipid, and protein composition of the breast tissue when compared with data from the reference standard chemical analysis. Conclusions: Accurate breast tissue decomposition can be done with three fold fewer projection images by the TFIR technique without any reduction in image spatial resolution and CNR. This can result in a two-third reduction of the patient dose in a multislit and multislice spiral CT system in addition to the reduced scanning time in this system. PMID:23464320
Hardware accelerator design for tracking in smart camera
NASA Astrophysics Data System (ADS)
Singh, Sanjay; Dunga, Srinivasa Murali; Saini, Ravi; Mandal, A. S.; Shekhar, Chandra; Vohra, Anil
2011-10-01
Smart Cameras are important components in video analysis. For video analysis, smart cameras needs to detect interesting moving objects, track such objects from frame to frame, and perform analysis of object track in real time. Therefore, the use of real-time tracking is prominent in smart cameras. The software implementation of tracking algorithm on a general purpose processor (like PowerPC) could achieve low frame rate far from real-time requirements. This paper presents the SIMD approach based hardware accelerator designed for real-time tracking of objects in a scene. The system is designed and simulated using VHDL and implemented on Xilinx XUP Virtex-IIPro FPGA. Resulted frame rate is 30 frames per second for 250x200 resolution video in gray scale.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stevens, Andrew; Kovarik, Libor; Abellan, Patricia
One of the main limitations of imaging at high spatial and temporal resolution during in-situ TEM experiments is the frame rate of the camera being used to image the dynamic process. While the recent development of direct detectors has provided the hardware to achieve frame rates approaching 0.1ms, the cameras are expensive and must replace existing detectors. In this paper, we examine the use of coded aperture compressive sensing methods [1, 2, 3, 4] to increase the framerate of any camera with simple, low-cost hardware modifications. The coded aperture approach allows multiple sub-frames to be coded and integrated into amore » single camera frame during the acquisition process, and then extracted upon readout using statistical compressive sensing inversion. Our simulations show that it should be possible to increase the speed of any camera by at least an order of magnitude. Compressive Sensing (CS) combines sensing and compression in one operation, and thus provides an approach that could further improve the temporal resolution while correspondingly reducing the electron dose rate. Because the signal is measured in a compressive manner, fewer total measurements are required. When applied to TEM video capture, compressive imaging couled improve acquisition speed and reduce the electron dose rate. CS is a recent concept, and has come to the forefront due the seminal work of Candès [5]. Since the publication of Candès, there has been enormous growth in the application of CS and development of CS variants. For electron microscopy applications, the concept of CS has also been recently applied to electron tomography [6], and reduction of electron dose in scanning transmission electron microscopy (STEM) imaging [7]. To demonstrate the applicability of coded aperture CS video reconstruction for atomic level imaging, we simulate compressive sensing on observations of Pd nanoparticles and Ag nanoparticles during exposure to high temperatures and other environmental conditions. Figure 1 highlights the results from the Pd nanoparticle experiment. On the left, 10 frames are reconstructed from a single coded frame—the original frames are shown for comparison. On the right a selection of three frames are shown from reconstructions at compression levels 10,20,30. The reconstructions, which are not post-processed, are true to the original and degrade in a straightforward manner. The final choice of compression level will obviously depend on both the temporal and spatial resolution required for a specific imaging task, but the results indicate that an increase in speed of better than an order of magnitude should be possible for all experiments. References: [1] P Llull, X Liao, X Yuan et al. Optics express 21(9), (2013), p. 10526. [2] J Yang, X Yuan, X Liao et al. Image Processing, IEEE Trans 23(11), (2014), p. 4863. [3] X Yuan, J Yang, P Llull et al. In ICIP 2013 (IEEE), p. 14. [4] X Yuan, P Llull, X Liao et al. In CVPR 2014. p. 3318. [5] EJ Candès, J Romberg and T Tao. Information Theory, IEEE Trans 52(2), (2006), p. 489. [6] P Binev, W Dahmen, R DeVore et al. In Modeling Nanoscale Imaging in Electron Microscopy, eds. T Vogt, W Dahmen and P Binev (Springer US), Nanostructure Science and Technology (2012). p. 73. [7] A Stevens, H Yang, L Carin et al. Microscopy 63(1), (2014), pp. 41.« less
Full-field OCT: applications in ophthalmology
NASA Astrophysics Data System (ADS)
Grieve, Kate; Dubois, Arnaud; Paques, Michel; Le Gargasson, Jean-Francois; Boccara, Albert C.
2005-04-01
We present images of ocular tissues obtained using ultrahigh resolution full-field OCT. The experimental setup is based on the Linnik interferometer, illuminated by a tungsten halogen lamp. En face tomographic images are obtained in real-time without scanning by computing the difference of two phase-opposed interferometric images recorded by a high-resolution CCD camera. A spatial resolution of 0.7 μm × 0.9 μm (axial × transverse) is achieved thanks to the short source coherence length and the use of high numerical aperture microscope objectives. A detection sensitivity of 90 dB is obtained by means of image averaging and pixel binning. Whole unfixed eyes and unstained tissue samples (cornea, lens, retina, choroid and sclera) of ex vivo rat, mouse, rabbit and porcine ocular tissues were examined. The unprecedented resolution of our instrument allows cellular-level resolution in the cornea and retina, and visualization of individual fibers in the lens. Transcorneal lens imaging was possible in all animals, and in albino animals, transscleral retinal imaging was achieved. We also introduce our rapid acquisition full-field optical coherence tomography system designed to accommodate in vivo ophthalmologic imaging. The variations on the original system technology include the introduction of a xenon arc lamp as source, and rapid image acquisition performed by a high-speed CMOS camera, reducing acquisition time to 5 ms per frame.
Automatic Mrf-Based Registration of High Resolution Satellite Video Data
NASA Astrophysics Data System (ADS)
Platias, C.; Vakalopoulou, M.; Karantzalos, K.
2016-06-01
In this paper we propose a deformable registration framework for high resolution satellite video data able to automatically and accurately co-register satellite video frames and/or register them to a reference map/image. The proposed approach performs non-rigid registration, formulates a Markov Random Fields (MRF) model, while efficient linear programming is employed for reaching the lowest potential of the cost function. The developed approach has been applied and validated on satellite video sequences from Skybox Imaging and compared with a rigid, descriptor-based registration method. Regarding the computational performance, both the MRF-based and the descriptor-based methods were quite efficient, with the first one converging in some minutes and the second in some seconds. Regarding the registration accuracy the proposed MRF-based method significantly outperformed the descriptor-based one in all the performing experiments.
Coronal Fine Structure in Dynamic Events Observed by Hi-C
NASA Technical Reports Server (NTRS)
Winebarger, Amy; Schuler, Timothy
2013-01-01
The High-Resolution Coronal Imager (Hi-C) flew aboard a NASA sounding rocket on 2012 July 11 and captured roughly 345 s of high spatial and temporal resolution images of the solar corona in a narrowband 193 Angstrom channel. We have analyzed the fluctuations in intensity of Active Region 11520. We selected events based on a lifetime greater than 11 s (two Hi-C frames) and intensities greater than a threshold determined from the photon and readout noise. We compare the Hi-C events with those determined from AIA. We find that HI-C detects shorter and smaller events than AIA. We also find that the intensity increase in the Hi-C events is approx. 3 times greater than the intensity increase in the AIA events we conclude the events are related to linear sub-structure that is unresolved by AIA
Scalable large format 3D displays
NASA Astrophysics Data System (ADS)
Chang, Nelson L.; Damera-Venkata, Niranjan
2010-02-01
We present a general framework for the modeling and optimization of scalable large format 3-D displays using multiple projectors. Based on this framework, we derive algorithms that can robustly optimize the visual quality of an arbitrary combination of projectors (e.g. tiled, superimposed, combinations of the two) without manual adjustment. The framework creates for the first time a new unified paradigm that is agnostic to a particular configuration of projectors yet robustly optimizes for the brightness, contrast, and resolution of that configuration. In addition, we demonstrate that our algorithms support high resolution stereoscopic video at real-time interactive frame rates achieved on commodity graphics hardware. Through complementary polarization, the framework creates high quality multi-projector 3-D displays at low hardware and operational cost for a variety of applications including digital cinema, visualization, and command-and-control walls.
Thermographic measurements of high-speed metal cutting
NASA Astrophysics Data System (ADS)
Mueller, Bernhard; Renz, Ulrich
2002-03-01
Thermographic measurements of a high-speed cutting process have been performed with an infrared camera. To realize images without motion blur the integration times were reduced to a few microseconds. Since the high tool wear influences the measured temperatures a set-up has been realized which enables small cutting lengths. Only single images have been recorded because the process is too fast to acquire a sequence of images even with the frame rate of the very fast infrared camera which has been used. To expose the camera when the rotating tool is in the middle of the camera image an experimental set-up with a light barrier and a digital delay generator with a time resolution of 1 ns has been realized. This enables a very exact triggering of the camera at the desired position of the tool in the image. Since the cutting depth is between 0.1 and 0.2 mm a high spatial resolution was also necessary which was obtained by a special close-up lens allowing a resolution of app. 45 microns. The experimental set-up will be described and infrared images and evaluated temperatures of a titanium alloy and a carbon steel will be presented for cutting speeds up to 42 m/s.
Cao, Weidong; Bean, Brian; Corey, Scott; Coursey, Johnathan S; Hasson, Kenton C; Inoue, Hiroshi; Isano, Taisuke; Kanderian, Sami; Lane, Ben; Liang, Hongye; Murphy, Brian; Owen, Greg; Shinoda, Nobuhiko; Zeng, Shulin; Knight, Ivor T
2016-06-01
We report the development of an automated genetic analyzer for human sample testing based on microfluidic rapid polymerase chain reaction (PCR) with high-resolution melting analysis (HRMA). The integrated DNA microfluidic cartridge was used on a platform designed with a robotic pipettor system that works by sequentially picking up different test solutions from a 384-well plate, mixing them in the tips, and delivering mixed fluids to the DNA cartridge. A novel image feedback flow control system based on a Canon 5D Mark II digital camera was developed for controlling fluid movement through a complex microfluidic branching network without the use of valves. The same camera was used for measuring the high-resolution melt curve of DNA amplicons that were generated in the microfluidic chip. Owing to fast heating and cooling as well as sensitive temperature measurement in the microfluidic channels, the time frame for PCR and HRMA was dramatically reduced from hours to minutes. Preliminary testing results demonstrated that rapid serial PCR and HRMA are possible while still achieving high data quality that is suitable for human sample testing. © 2015 Society for Laboratory Automation and Screening.
An Acoustic Charge Transport Imager for High Definition Television
NASA Technical Reports Server (NTRS)
Hunt, William D.; Brennan, Kevin; May, Gary; Glenn, William E.; Richardson, Mike; Solomon, Richard
1999-01-01
This project, over its term, included funding to a variety of companies and organizations. In addition to Georgia Tech these included Florida Atlantic University with Dr. William E. Glenn as the P.I., Kodak with Mr. Mike Richardson as the P.I. and M.I.T./Polaroid with Dr. Richard Solomon as the P.I. The focus of the work conducted by these organizations was the development of camera hardware for High Definition Television (HDTV). The focus of the research at Georgia Tech was the development of new semiconductor technology to achieve a next generation solid state imager chip that would operate at a high frame rate (I 70 frames per second), operate at low light levels (via the use of avalanche photodiodes as the detector element) and contain 2 million pixels. The actual cost required to create this new semiconductor technology was probably at least 5 or 6 times the investment made under this program and hence we fell short of achieving this rather grand goal. We did, however, produce a number of spin-off technologies as a result of our efforts. These include, among others, improved avalanche photodiode structures, significant advancement of the state of understanding of ZnO/GaAs structures and significant contributions to the analysis of general GaAs semiconductor devices and the design of Surface Acoustic Wave resonator filters for wireless communication. More of these will be described in the report. The work conducted at the partner sites resulted in the development of 4 prototype HDTV cameras. The HDTV camera developed by Kodak uses the Kodak KAI-2091M high- definition monochrome image sensor. This progressively-scanned charge-coupled device (CCD) can operate at video frame rates and has 9 gm square pixels. The photosensitive area has a 16:9 aspect ratio and is consistent with the "Common Image Format" (CIF). It features an active image area of 1928 horizontal by 1084 vertical pixels and has a 55% fill factor. The camera is designed to operate in continuous mode with an output data rate of 5MHz, which gives a maximum frame rate of 4 frames per second. The MIT/Polaroid group developed two cameras under this program. The cameras have effectively four times the current video spatial resolution and at 60 frames per second are double the normal video frame rate.
Integration of High-resolution Data for Temporal Bone Surgical Simulations
Wiet, Gregory J.; Stredney, Don; Powell, Kimerly; Hittle, Brad; Kerwin, Thomas
2016-01-01
Purpose To report on the state of the art in obtaining high-resolution 3D data of the microanatomy of the temporal bone and to process that data for integration into a surgical simulator. Specifically, we report on our experience in this area and discuss the issues involved to further the field. Data Sources Current temporal bone image acquisition and image processing established in the literature as well as in house methodological development. Review Methods We reviewed the current English literature for the techniques used in computer-based temporal bone simulation systems to obtain and process anatomical data for use within the simulation. Search terms included “temporal bone simulation, surgical simulation, temporal bone.” Articles were chosen and reviewed that directly addressed data acquisition and processing/segmentation and enhancement with emphasis given to computer based systems. We present the results from this review in relationship to our approach. Conclusions High-resolution CT imaging (≤100μm voxel resolution), along with unique image processing and rendering algorithms, and structure specific enhancement are needed for high-level training and assessment using temporal bone surgical simulators. Higher resolution clinical scanning and automated processes that run in efficient time frames are needed before these systems can routinely support pre-surgical planning. Additionally, protocols such as that provided in this manuscript need to be disseminated to increase the number and variety of virtual temporal bones available for training and performance assessment. PMID:26762105
Geomorphological Mapping of Sputnik Planum and Surrounding Terrain on Pluto
NASA Astrophysics Data System (ADS)
White, Oliver; Stern, Alan; Weaver, Hal; Olkin, Cathy; Ennico, Kimberly; Young, Leslie; Moore, Jeff
2015-11-01
The New Horizons flyby of Pluto in July 2015 has provided the first few close-up images of the Kuiper belt object, which reveal it to have a highly diverse range of terrains, implying a complex geological history. The highest resolution images that have yet been returned are seven lossy 400 m/pixel frames that cover the majority of the prominent Plutonian feature informally named Sputnik Planum (all feature names are currently informal), and its surroundings. This resolution is sufficient to allow detailed geomorphological mapping of this area to commence. Lossless versions of all 15 frames that make up the mosaic will be returned in September 2015, and the map presented at DPS will incorporate the total area covered by these frames.Sputnik Planum, with an area of ~650,000 km2, is notable for its smooth appearance and apparent total lack of impact craters at 400 m/pixel resolution. The Planum actually displays a wide variety of textures across its expanse, which includes smooth and pitted plains to the south, polygonal terrain at its center (the polygons can reach tens of kilometers in size and are bounded by troughs that sometimes feature central ridges), and, to the north, darker polygonal terrain displaying patterns indicative of glacial flow. Within these plains there exist several well-defined outcrops of a mottled, light/dark unit that reach from several to tens of kilometers across. Separating Sputnik Planum from the dark, cratered equatorial terrain of Cthulhu Regio on its south-western margin is a unit of chaotically arranged mountains (Hillary Montes); similar mountainous units exist on the south and western margins. The northern margin is bounded by rugged, hilly, cratered terrain (Cousteau Rupes) into which ice of Sputnik Planum appears to be intruding in places. Terrain of similar relief exists to the east, but is much brighter than that to the north. The southernmost extent of the mosaic features a unit of rough, undulating terrain (Pandemonium Dorsa) that displays very few impact craters at 400 m/pixel resolution.This work was supported by the NASA New Horizons project.
An Attention-Information-Based Spatial Adaptation Framework for Browsing Videos via Mobile Devices
NASA Astrophysics Data System (ADS)
Li, Houqiang; Wang, Yi; Chen, Chang Wen
2007-12-01
With the growing popularity of personal digital assistant devices and smart phones, more and more consumers are becoming quite enthusiastic to appreciate videos via mobile devices. However, limited display size of the mobile devices has been imposing significant barriers for users to enjoy browsing high-resolution videos. In this paper, we present an attention-information-based spatial adaptation framework to address this problem. The whole framework includes two major parts: video content generation and video adaptation system. During video compression, the attention information in video sequences will be detected using an attention model and embedded into bitstreams with proposed supplement-enhanced information (SEI) structure. Furthermore, we also develop an innovative scheme to adaptively adjust quantization parameters in order to simultaneously improve the quality of overall encoding and the quality of transcoding the attention areas. When the high-resolution bitstream is transmitted to mobile users, a fast transcoding algorithm we developed earlier will be applied to generate a new bitstream for attention areas in frames. The new low-resolution bitstream containing mostly attention information, instead of the high-resolution one, will be sent to users for display on the mobile devices. Experimental results show that the proposed spatial adaptation scheme is able to improve both subjective and objective video qualities.
Full-field OCT: ex vivo and in vivo biological imaging applications
NASA Astrophysics Data System (ADS)
Grieve, Katharine; Dubois, Arnaud; Moneron, Gael; Guyot, Elvire; Boccara, Albert C.
2005-04-01
We present results of studies in embryology and ophthalmology performed using our ultrahigh-resolution full-field OCT system. We also discuss recent developments to our ultrashort acquisition time full-field optical coherence tomography system designed to allow in vivo biological imaging. Preliminary results of high-speed imaging in biological samples are presented. The core of the experimental setup is the Linnik interferometer, illuminated by a white light source. En face tomographic images are obtained in real-time without scanning by computing the difference of two phase-opposed interferometric images recorded by high-resolution CCD cameras. An isotropic spatial resolution of ~1 μm is achieved thanks to the short source coherence length and the use of high numerical aperture microscope objectives. A detection sensitivity of ~90 dB is obtained by means of image averaging and pixel binning. In ophthalmology, reconstructed xz images from rat ocular tissue are presented, where cellular-level structures in the retina are revealed, demonstrating the unprecedented resolution of our instrument. Three-dimensional reconstructions of the mouse embryo allowing the study of the establishment of the anterior-posterior axis are shown. Finally we present the first results of embryonic imaging using the new rapid acquisition full-field OCT system, which offers an acquisition time of 10 μs per frame.
New sesquiterpenes from Euonymus europaeus (Celastraceae).
Descoins, Charles; Bazzocchi, Isabel López; Ravelo, Angel Gutiérrez
2002-02-01
A new sesquiterpene evoninate alkaloid (1), and two sesquiterpenes (2, 3) with a dihydro-beta-agarofuran skeleton, along with three known sesquiterpenes (4-6), were isolated from the seeds of Euonymus europaeus. Their structures were elucidated by high resolution mass analysis, and one- and two-dimensional (1D and 2D) NMR spectroscopy, including homonuclear and heteronuclear correlation [correlation spectroscopy (COSY), rotating frame Overhauser enhancement spectroscopy (ROESY), heteronuclear single quantum coherence (HSQC), and heteronuclear multiple bond correlation (HMBC)] experiments.
Highest Resolution Comet Picture Ever Reveals Rugged Terrain - Deep Space 1
2001-11-04
In this highest resolution view of the icy, rocky nucleus of comet Borrelly, (about 45 meters or 150 feet per pixel) a variety of terrains and surface textures, mountains and fault structures, and darkened material are visible over the nucleus's surface. This was the final image of the nucleus of comet Borrelly, taken just 160 seconds before Deep Space1's closest approach to it. This image shows the 8-km (5-mile) long nucleus about 3417 kilometers (over 2,000 miles) away. Smooth, rolling plains containing brighter regions are present in the middle of the nucleus and seem to be the source of dust jets seen in the coma. The rugged land found at both ends of the nucleus has many high ridges along the jagged line between day and night on the comet. This rough terrain contains very dark patches that appear to be elevated compared to surrounding areas. In some places the dark material accentuates grooves and apparent faults. Stereo analysis shows the smaller end of the nucleus (lower right) is tipped toward the viewer (out of frame). Sunlight is coming from the bottom of the frame. http://photojournal.jpl.nasa.gov/catalog/PIA03500
Deliyski, Dimitar D; Powell, Maria EG; Zacharias, Stephanie RC; Gerlach, Terri Treman; de Alarcon, Alessandro
2015-01-01
This study investigated the impact of high-speed videoendoscopy (HSV) frame rates on the assessment of nine clinically-relevant vocal-fold vibratory features. Fourteen adult patients with voice disorder and 14 adult normal controls were recorded using monochromatic rigid HSV at a rate of 16000 frames per second (fps) and spatial resolution of 639×639 pixels. The 16000-fps data were downsampled to 16 other rate denominations. Using paired comparisons design, nine common clinical vibratory features were visually compared between the downsampled and the original images. Three raters reported the thresholds at which: (1) a detectable difference between the two videos was first noticed, and (2) differences between the two videos would result in a change of clinical rating. Results indicated that glottal edge, mucosal wave magnitude and extent, aperiodicity, contact and loss of contact of the vocal folds were the vibratory features most sensitive to frame rate. Of these vibratory features, the glottal edge was selected for further analysis, due to its higher rating reliability, universal prevalence and consistent definition. Rates of 8000 fps were found to be free from visually-perceivable feature degradation, and for rates of 5333 fps, degradation was minimal. For rates of 4000 fps and higher, clinical assessments of glottal edge were not affected. Rates of 2000 fps changed the clinical ratings in over 16% of the samples, which could lead to inaccurate functional assessment. PMID:28989342
NASA Astrophysics Data System (ADS)
Seo, Hokuto; Aihara, Satoshi; Namba, Masakazu; Watabe, Toshihisa; Ohtake, Hiroshi; Kubota, Misao; Egami, Norifumi; Hiramatsu, Takahiro; Matsuda, Tokiyoshi; Furuta, Mamoru; Nitta, Hiroshi; Hirao, Takashi
2010-01-01
Our group has been developing a new type of image sensor overlaid with three organic photoconductive films, which are individually sensitive to only one of the primary color components (blue (B), green (G), or red (R) light), with the aim of developing a compact, high resolution color camera without any color separation optical systems. In this paper, we firstly revealed the unique characteristics of organic photoconductive films. Only choosing organic materials can tune the photoconductive properties of the film, especially excellent wavelength selectivities which are good enough to divide the incident light into three primary colors. Color separation with vertically stacked organic films was also shown. In addition, the high-resolution of organic photoconductive films sufficient for high-definition television (HDTV) was confirmed in a shooting experiment using a camera tube. Secondly, as a step toward our goal, we fabricated a stacked organic image sensor with G- and R-sensitive organic photoconductive films, each of which had a zinc oxide (ZnO) thin film transistor (TFT) readout circuit, and demonstrated image pickup at a TV frame rate. A color image with a resolution corresponding to the pixel number of the ZnO TFT readout circuit was obtained from the stacked image sensor. These results show the potential for the development of high-resolution prism-less color cameras with stacked organic photoconductive films.
NASA Astrophysics Data System (ADS)
Chen, Jianyu; Mao, Zhihua; He, Xianqiang
2009-01-01
Coral reefs are complex marine ecosystems that are constructed and maintained by biological communities that thrive in tropical oceans. The Dong-Sha Atoll is located at the northern continental margin of the South China Sea. It has being abused by destructive activity of human being and natural event during recent decades. Remote sensing offers a powerful tool for studying coral reef geomorphology and is the most cost-effective approach for large-scale reef survey. In this paper, the high-resolution Quickbird2 imageries which covered the full atoll are used to categorize the current distribution of coral reefs geomorphological structure therein with the auxiliary SPOT5 and ASTER imageries. Spectral and texture analysis are used to distinguish the geomorphological diversity during data processing. The Gray Level Co-occurrence Matrices is adopted for texture feature extraction and atoll geomorphology mapping in the high-resolution pan-color image of Quickbird2. Quickbird2 is considered as the most appropriate image source for coral reefs studies. In the Dong-Sha Atoll, various dynamical geomorphologic units are developed according to wave energy zones. There the reef frame types are classified to 3 different types according as its diversity at the image. The radial structure system is the most characteristic and from high resolution imagery we can distinguish the discrepancy between them.
Noise and sensitivity of x-ray framing cameras at Nike (abstract)
NASA Astrophysics Data System (ADS)
Pawley, C. J.; Deniz, A. V.; Lehecka, T.
1999-01-01
X-ray framing cameras are the most widely used tool for radiographing density distributions in laser and Z-pinch driven experiments. The x-ray framing cameras that were developed specifically for experiments on the Nike laser system are described. One of these cameras has been coupled to a CCD camera and was tested for resolution and image noise using both electrons and x rays. The largest source of noise in the images was found to be due to low quantum detection efficiency of x-ray photons.
Geiger-mode APD camera system for single-photon 3D LADAR imaging
NASA Astrophysics Data System (ADS)
Entwistle, Mark; Itzler, Mark A.; Chen, Jim; Owens, Mark; Patel, Ketan; Jiang, Xudong; Slomkowski, Krystyna; Rangwala, Sabbir
2012-06-01
The unparalleled sensitivity of 3D LADAR imaging sensors based on single photon detection provides substantial benefits for imaging at long stand-off distances and minimizing laser pulse energy requirements. To obtain 3D LADAR images with single photon sensitivity, we have demonstrated focal plane arrays (FPAs) based on InGaAsP Geiger-mode avalanche photodiodes (GmAPDs) optimized for use at either 1.06 μm or 1.55 μm. These state-of-the-art FPAs exhibit excellent pixel-level performance and the capability for 100% pixel yield on a 32 x 32 format. To realize the full potential of these FPAs, we have recently developed an integrated camera system providing turnkey operation based on FPGA control. This system implementation enables the extremely high frame-rate capability of the GmAPD FPA, and frame rates in excess of 250 kHz (for 0.4 μs range gates) can be accommodated using an industry-standard CameraLink interface in full configuration. Real-time data streaming for continuous acquisition of 2 μs range gate point cloud data with 13-bit time-stamp resolution at 186 kHz frame rates has been established using multiple solid-state storage drives. Range gate durations spanning 4 ns to 10 μs provide broad operational flexibility. The camera also provides real-time signal processing in the form of multi-frame gray-scale contrast images and single-frame time-stamp histograms, and automated bias control has been implemented to maintain a constant photon detection efficiency in the presence of ambient temperature changes. A comprehensive graphical user interface has been developed to provide complete camera control using a simple serial command set, and this command set supports highly flexible end-user customization.
View of Callisto at Increasing Resolutions
NASA Technical Reports Server (NTRS)
1998-01-01
These four views of Jupiter's second largest moon, Callisto, highlight how increasing resolutions enable interpretation of the surface. In the global view (top left) the surface is seen to have many small bright spots, while the regional view (top right) reveals the spots to be the larger craters. The local view (bottom right) not only brings out smaller craters and detailed structure of larger craters, but also shows a smooth dark layer of material that appears to cover much of the surface. The close-up frame (bottom left) presents a surprising smoothness in this highest resolution (30 meters per picture element) view of Callisto's surface.
North is to the top of these frames which were taken by the Solid State Imaging (SSI) system on NASA's Galileo spacecraft between November 1996 and November 1997. Even higher resolution images (better than 20 meters per picture element) of Callisto will be taken on June 30, 1999 during the 21st orbit of the spacecraft around Jupiter.The top left frame is scaled to 10 kilometers (km) per picture element (pixel) and covers an area about 4400 by 2500 km. The moon Callisto, which has a diameter of 4806 km, appears to be peppered with many bright spots. Images at this resolution of other cratered moons in the Solar System indicate that the bright spots could be impact craters. The ring structure of Valhalla, the largest impact structure on Callisto, is visible in the center of the frame. This color view combines images obtained in November 1997 taken through the green, violet, and 1 micrometer filters of the SSI system.The top right frame is ten times higher resolution (about 1 km per pixel) and covers an area approximately 440 by 250 km. Craters, which are clearly recognizable, appear to be the dominant landform on Callisto. The crater rims appear bright, while the adjacent area and the crater interiors are dark. This resolution is comparable to the best data available from the 1979 flyby's of NASA's two Voyager spacecraft; it reflects the understanding of Callisto prior to new data from Galileo. This Galileo image was taken in November 1996.The resolution of the bottom right image is again ten times better (100 meters per pixel) and covering an area of about 44 by 25 km. This resolution reveals that some crater rims are not complete rings, but are composed of bright isolated segments. Steep slopes near crater rims reveal dark material that appears to have slid down to reveal bright material. The thickness of the dark layer could be tens of meters. The image was taken in June 1997.The bottom left image at about 29 meters per pixel is the highest resolution available for Callisto. It covers an area about 4.4 by 2.5 km and is somewhat oblique. Craters are visible but no longer dominate the surface. The image was taken in November 1996.The Jet Propulsion Laboratory, Pasadena, CA manages the Galileo mission for NASA's Office of Space Science, Washington, DC. JPL is an operating division of California Institute of Technology (Caltech).This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov. Background information and educational context for the images can be found at URL http://www.jpl.nasa.gov/galileo/sepo47 CFR 73.9003 - Compliance requirements for covered demodulator products: Unscreened content.
Code of Federal Regulations, 2010 CFR
2010-10-01
... operating in a mode compatible with the digital visual interface (DVI) rev. 1.0 Specification as an image having the visual equivalent of no more than 350,000 pixels per frame (e.g. an image with resolution of 720×480 pixels for a 4:3 (nonsquare pixel) aspect ratio), and 30 frames per second. Such an image may...
47 CFR 73.9004 - Compliance requirements for covered demodulator products: Marked content.
Code of Federal Regulations, 2010 CFR
2010-10-01
... compatible with the digital visual interface (DVI) Rev. 1.0 Specification as an image having the visual equivalent of no more than 350,000 pixels per frame (e.g., an image with resolution of 720×480 pixels for a 4:3 (nonsquare pixel) aspect ratio), and 30 frames per second. Such an image may be attained by...
Image Quality in High-resolution and High-cadence Solar Imaging
NASA Astrophysics Data System (ADS)
Denker, C.; Dineva, E.; Balthasar, H.; Verma, M.; Kuckein, C.; Diercke, A.; González Manrique, S. J.
2018-03-01
Broad-band imaging and even imaging with a moderate bandpass (about 1 nm) provides a photon-rich environment, where frame selection (lucky imaging) becomes a helpful tool in image restoration, allowing us to perform a cost-benefit analysis on how to design observing sequences for imaging with high spatial resolution in combination with real-time correction provided by an adaptive optics (AO) system. This study presents high-cadence (160 Hz) G-band and blue continuum image sequences obtained with the High-resolution Fast Imager (HiFI) at the 1.5-meter GREGOR solar telescope, where the speckle-masking technique is used to restore images with nearly diffraction-limited resolution. The HiFI employs two synchronized large-format and high-cadence sCMOS detectors. The median filter gradient similarity (MFGS) image-quality metric is applied, among others, to AO-corrected image sequences of a pore and a small sunspot observed on 2017 June 4 and 5. A small region of interest, which was selected for fast-imaging performance, covered these contrast-rich features and their neighborhood, which were part of Active Region NOAA 12661. Modifications of the MFGS algorithm uncover the field- and structure-dependency of this image-quality metric. However, MFGS still remains a good choice for determining image quality without a priori knowledge, which is an important characteristic when classifying the huge number of high-resolution images contained in data archives. In addition, this investigation demonstrates that a fast cadence and millisecond exposure times are still insufficient to reach the coherence time of daytime seeing. Nonetheless, the analysis shows that data acquisition rates exceeding 50 Hz are required to capture a substantial fraction of the best seeing moments, significantly boosting the performance of post-facto image restoration.
Accelerated high-resolution photoacoustic tomography via compressed sensing
NASA Astrophysics Data System (ADS)
Arridge, Simon; Beard, Paul; Betcke, Marta; Cox, Ben; Huynh, Nam; Lucka, Felix; Ogunlade, Olumide; Zhang, Edward
2016-12-01
Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue (4D PAT). A particular example is the planar Fabry-Pérot (FP) photoacoustic scanner, which yields high-resolution 3D images but takes several minutes to sequentially map the incident photoacoustic field on the 2D sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant. We demonstrate that combining model-based, variational image reconstruction methods using spatial sparsity constraints with the development of novel PAT acquisition systems capable of sub-sampling the acoustic wave field can dramatically increase the acquisition speed while maintaining a good spatial resolution: first, we describe and model two general spatial sub-sampling schemes. Then, we discuss how to implement them using the FP interferometer and demonstrate the potential of these novel compressed sensing PAT devices through simulated data from a realistic numerical phantom and through measured data from a dynamic experimental phantom as well as from in vivo experiments. Our results show that images with good spatial resolution and contrast can be obtained from highly sub-sampled PAT data if variational image reconstruction techniques that describe the tissues structures with suitable sparsity-constraints are used. In particular, we examine the use of total variation (TV) regularization enhanced by Bregman iterations. These novel reconstruction strategies offer new opportunities to dramatically increase the acquisition speed of photoacoustic scanners that employ point-by-point sequential scanning as well as reducing the channel count of parallelized schemes that use detector arrays.
High-resolution Ceres HAMO Atlas derived from Dawn FC Images
NASA Astrophysics Data System (ADS)
Roatsch, T.; Kersten, E.; Matz, K. D.; Preusker, F.; Scholten, F.; Jaumann, R.; Raymond, C. A.; Russell, C. T.
2015-12-01
Introduction: NASA's Dawn spacecraft will orbit the dwarf planet Ceres in August and September 2015 in HAMO (High Altitude Mapping Orbit) with an altitude of about 1,500 km to characterize for instance the geology, topography, and shape of Ceres before it will be transferred to the lowest orbit. One of the major goals of this mission phase is the global mapping of Ceres. Data: The Dawn mission is equipped with a fram-ing camera (FC). The framing camera will take about 2600 clear filter images with a resolution of about 120 m/pixel and different viewing angles and different illumination conditions. Data Processing: The first step of the processing chain towards the cartographic products is to ortho-rectify the images to the proper scale and map projec-tion type. This process requires detailed information of the Dawn orbit and attitude data and of the topography of the target. Both, improved orientation and high-resolution shape models, are provided by stereo processing of the HAMO dataset. Ceres' HAMO shape model is used for the calculation of the ray intersection points while the map projection itself will be done onto a reference sphere for Ceres. The final step is the controlled mosaicking of all nadir images to a global mosaic of Ceres, the so called basemap. Ceres map tiles: The Ceres atlas will be produced in a scale of 1:750,000 and will consist of 15 tiles that conform to the quadrangle schema for small planets and medium size Icy satellites. A map scale of 1:750,000 guarantees a mapping at the highest availa-ble Dawn resolution in HAMO. Nomenclature: The Dawn team proposed to the International Astronomical Union (IAU) to use the names of gods and goddesses of agriculture and vege-tation from world mythology as names for the craters. This proposal was accepted by the IAU and the team proposed names for geological features to the IAU based on the HAMO mosaic. These feature names will be applied to the map tiles.
Public-Requested Mars Image: Crater on Pavonis Mons
NASA Technical Reports Server (NTRS)
2003-01-01
MGS MOC Release No. MOC2-481, 12 September 2003
This image is in the first pair obtained in the Public Target Request program, which accepts suggestions for sites to photograph with the Mars Orbiter Camera on NASA's Mars Global Surveyor spacecraft.It is a narrow-angle (high-resolution) view of a portion of the lower wall and floor of the caldera at the top of a martian volcano named Pavonis Mons. A companion picture is a wide-angle context image, taken at the same time as the high-resolution view. The white box in the context frame shows the location of the high-resolution picture. [figure removed for brevity, see original site] Pavonis Mons is a broad shield volcano. Its summit region is about 14 kilometers (8.7 miles) above the martian datum (zero-elevation reference level). The caldera is about 4.6 kilometers (2.8 miles) deep. The caldera formed by collapse--long ago--as molten rock withdrew to greater depths within the volcano. The high-resolution picture shows that today the floor and walls of this caldera are covered by a thick, textured mantle of dust, perhaps more than 1 meter (1 yard) deep. Larger boulders and rock outcroppings poke out from within this dust mantle. They are seen as small, dark dots and mounds on the lower slopes of the wall in the high-resolution image. The narrow-angle Mars Orbiter Camera image has a resolution of 1.5 meters (about 5 feet) per pixel and covers an area 1.5 kilometers (0.9 mile) wide by 9 kilometers (5.6 miles) long. The context image, covering much of the summit region of Pavonis Mons, is about 115 kilometers (72 miles) wide. Sunlight illuminates both images from the lower left; north is toward the upper right; east to the right. The high-resolution view is located near 0.4 degrees north latitude, 112.8 degrees west longitude.NASA Astrophysics Data System (ADS)
Hernandez, F.; Liang, X.
2017-12-01
Reliable real-time hydrological forecasting, to predict important phenomena such as floods, is invaluable to the society. However, modern high-resolution distributed models have faced challenges when dealing with uncertainties that are caused by the large number of parameters and initial state estimations involved. Therefore, to rely on these high-resolution models for critical real-time forecast applications, considerable improvements on the parameter and initial state estimation techniques must be made. In this work we present a unified data assimilation algorithm called Optimized PareTo Inverse Modeling through Inverse STochastic Search (OPTIMISTS) to deal with the challenge of having robust flood forecasting for high-resolution distributed models. This new algorithm combines the advantages of particle filters and variational methods in a unique way to overcome their individual weaknesses. The analysis of candidate particles compares model results with observations in a flexible time frame, and a multi-objective approach is proposed which attempts to simultaneously minimize differences with the observations and departures from the background states by using both Bayesian sampling and non-convex evolutionary optimization. Moreover, the resulting Pareto front is given a probabilistic interpretation through kernel density estimation to create a non-Gaussian distribution of the states. OPTIMISTS was tested on a low-resolution distributed land surface model using VIC (Variable Infiltration Capacity) and on a high-resolution distributed hydrological model using the DHSVM (Distributed Hydrology Soil Vegetation Model). In the tests streamflow observations are assimilated. OPTIMISTS was also compared with a traditional particle filter and a variational method. Results show that our method can reliably produce adequate forecasts and that it is able to outperform those resulting from assimilating the observations using a particle filter or an evolutionary 4D variational method alone. In addition, our method is shown to be efficient in tackling high-resolution applications with robust results.
NASA Astrophysics Data System (ADS)
Osada, Masakazu; Tsukui, Hideki
2002-09-01
ABSTRACT Picture Archiving and Communication System (PACS) is a system which connects imaging modalities, image archives, and image workstations to reduce film handling cost and improve hospital workflow. Handling diagnostic ultrasound and endoscopy images is challenging, because it produces large amount of data such as motion (cine) images of 30 frames per second, 640 x 480 in resolution, with 24-bit color. Also, it requires enough image quality for clinical review. We have developed PACS which is able to manage ultrasound and endoscopy cine images with above resolution and frame rate, and investigate suitable compression method and compression rate for clinical image review. Results show that clinicians require capability for frame-by-frame forward and backward review of cine images because they carefully look through motion images to find certain color patterns which may appear in one frame. In order to satisfy this quality, we have chosen motion JPEG, installed and confirmed that we could capture this specific pattern. As for acceptable image compression rate, we have performed subjective evaluation. No subjects could tell the difference between original non-compressed images and 1:10 lossy compressed JPEG images. One subject could tell the difference between original and 1:20 lossy compressed JPEG images although it is acceptable. Thus, ratios of 1:10 to 1:20 are acceptable to reduce data amount and cost while maintaining quality for clinical review.
Weavers, Paul T; Borisch, Eric A; Hulshizer, Tom C; Rossman, Phillip J; Young, Phillip M; Johnson, Casey P; McKay, Jessica; Cline, Christopher C; Riederer, Stephen J
2016-04-01
Three-station stepping-table time-resolved 3D contrast-enhanced magnetic resonance angiography has conflicting demands in the need to limit acquisition time in proximal stations to match the speed of the advancing contrast bolus and in the distal-most station to avoid venous contamination while still providing clinically useful spatial resolution. This work describes improved receiver coil arrays which address this issue by allowing increased acceleration factors, providing increased spatial resolution per unit time. Receiver coil arrays were constructed for each station (pelvis, thigh, calf) and then integrated into a 48-element array for three-station peripheral CE-MRA. Coil element sizes and array configurations for these three stations were designed to improve SENSE-type parallel imaging taking advantage of an increase in coil count for all stations versus the previous 32 channel capability. At each station either acceleration apportionment or optimal CAIPIRINHA selection was used to choose the optimum acceleration parameters for each subject. Results were evaluated in both single- and multi-station studies. Single-station studies showed that SENSE acceleration in the thigh station could be readily increased from R=8 to R=10, allowing reduction of the frame time from 2.5 to 2.1 s to better image the typically rapidly advancing bolus at this station. Similarly, the improved coil array for the calf station permitted acceleration increase from R=8 to R=12, providing a 4.0 vs. 5.2 s frame time. Results in three-station studies suggest an improved ability to track the contrast bolus in peripheral CE-MRA. Modified receiver coil arrays and individualized parameter optimization have been used to provide improved acceleration at all stations in multi-station peripheral CE-MRA and provide high spatial resolution with frame times as short as 2.1 s. Copyright © 2015 Elsevier Inc. All rights reserved.
Ultrafast electron diffraction and electron microscopy: present status and future prospects
NASA Astrophysics Data System (ADS)
Ishchenko, A. A.; Aseyev, S. A.; Bagratashvili, V. N.; Panchenko, V. Ya; Ryabov, E. A.
2014-07-01
Acting as complementary research tools, high time-resolved spectroscopy and diffractometry techniques proceeding from various physical principles open up new possibilities for studying matter with necessary integration of the 'structure-dynamics-function' triad in physics, chemistry, biology and materials science. Since the 1980s, a new field of research has started at the leading research laboratories, aimed at developing means of filming the coherent dynamics of nuclei in molecules and fast processes in biological objects ('atomic and molecular movies'). The utilization of ultrashort laser pulse sources has significantly modified traditional electron beam approaches to and provided high space-time resolution for the study of materials. Diffraction methods using frame-by-frame filming and the development of the main principles of the study of coherent dynamics of atoms have paved the way to observing wave packet dynamics, the intermediate states of reaction centers, and the dynamics of electrons in molecules, thus allowing a transition from the kinetics to the dynamics of the phase trajectories of molecules in the investigation of chemical reactions.
Motion compensation and noise tolerance in phase-shifting digital in-line holography.
Stenner, Michael D; Neifeld, Mark A
2006-05-15
We present a technique for phase-shifting digital in-line holography which compensates for lateral object motion. By collecting two frames of interference between object and reference fields with identical reference phase, one can estimate the lateral motion that occurred between frames using the cross-correlation. We also describe a very general linear framework for phase-shifting holographic reconstruction which minimizes additive white Gaussian noise (AWGN) for an arbitrary set of reference field amplitudes and phases. We analyze the technique's sensitivity to noise (AWGN, quantization, and shot), errors in the reference fields, errors in motion estimation, resolution, and depth of field. We also present experimental motion-compensated images achieving the expected resolution.
NASA Astrophysics Data System (ADS)
Bourgeois, E.; Bokanowski, O.; Zidani, H.; Désilles, A.
2018-06-01
The resolution of the launcher ascent trajectory problem by the so-called Hamilton-Jacobi-Bellman (HJB) approach, relying on the Dynamic Programming Principle, has been investigated. The method gives a global optimum and does not need any initialization procedure. Despite these advantages, this approach is seldom used because of the dicculties of computing the solution of the HJB equation for high dimension problems. The present study shows that an eccient resolution is found. An illustration of the method is proposed on a heavy class launcher, for a typical GEO (Geostationary Earth Orbit) mission. This study has been performed in the frame of the Centre National d'Etudes Spatiales (CNES) Launchers Research & Technology Program.
KPFM/AFM imaging on TiO2(110) surface in O2 gas
NASA Astrophysics Data System (ADS)
Arima, Eiji; Wen, Huan Fei; Naitoh, Yoshitaka; Li, Yan Jun; Sugawara, Yasuhiro
2018-03-01
We have carried out high-speed imaging of the topography and local contact potential difference (LCPD) on rutile TiO2(110) in O2 gas by atomic force microscopy (AFM) and Kelvin probe force microscopy (KPFM). We succeeded in KPFM/AFM imaging with atomic resolution at 1 frame min-1 and observed the adsorbate on a hydroxylated TiO2(110) surface. The observed adsorbate is considered to be oxygen adatoms (Oa), hydroperoxyls (HO2), or terminal hydroxyls (OHt). After adsorption, changes in the topography and the LCPD of the adsorbate were observed. This phenomenon is thought to be caused by the charge transfer of the adsorbate. This technique has the potential to observe catalytic behavior with atomic resolution.
Low-Light Image Enhancement Using Adaptive Digital Pixel Binning
Yoo, Yoonjong; Im, Jaehyun; Paik, Joonki
2015-01-01
This paper presents an image enhancement algorithm for low-light scenes in an environment with insufficient illumination. Simple amplification of intensity exhibits various undesired artifacts: noise amplification, intensity saturation, and loss of resolution. In order to enhance low-light images without undesired artifacts, a novel digital binning algorithm is proposed that considers brightness, context, noise level, and anti-saturation of a local region in the image. The proposed algorithm does not require any modification of the image sensor or additional frame-memory; it needs only two line-memories in the image signal processor (ISP). Since the proposed algorithm does not use an iterative computation, it can be easily embedded in an existing digital camera ISP pipeline containing a high-resolution image sensor. PMID:26121609
Ping Gong; Pengfei Song; Shigao Chen
2017-06-01
The development of ultrafast ultrasound imaging offers great opportunities to improve imaging technologies, such as shear wave elastography and ultrafast Doppler imaging. In ultrafast imaging, there are tradeoffs among image signal-to-noise ratio (SNR), resolution, and post-compounded frame rate. Various approaches have been proposed to solve this tradeoff, such as multiplane wave imaging or the attempts of implementing synthetic transmit aperture imaging. In this paper, we propose an ultrafast synthetic transmit aperture (USTA) imaging technique using Hadamard-encoded virtual sources with overlapping sub-apertures to enhance both image SNR and resolution without sacrificing frame rate. This method includes three steps: 1) create virtual sources using sub-apertures; 2) encode virtual sources using Hadamard matrix; and 3) add short time intervals (a few microseconds) between transmissions of different virtual sources to allow overlapping sub-apertures. The USTA was tested experimentally with a point target, a B-mode phantom, and in vivo human kidney micro-vessel imaging. Compared with standard coherent diverging wave compounding with the same frame rate, improvements on image SNR, lateral resolution (+33%, with B-mode phantom imaging), and contrast ratio (+3.8 dB, with in vivo human kidney micro-vessel imaging) have been achieved. The f-number of virtual sources, the number of virtual sources used, and the number of elements used in each sub-aperture can be flexibly adjusted to enhance resolution and SNR. This allows very flexible optimization of USTA for different applications.
Strategic options towards an affordable high-performance infrared camera
NASA Astrophysics Data System (ADS)
Oduor, Patrick; Mizuno, Genki; Dutta, Achyut K.; Lewis, Jay; Dhar, Nibir K.
2016-05-01
The promise of infrared (IR) imaging attaining low-cost akin to CMOS sensors success has been hampered by the inability to achieve cost advantages that are necessary for crossover from military and industrial applications into the consumer and mass-scale commercial realm despite well documented advantages. Banpil Photonics is developing affordable IR cameras by adopting new strategies to speed-up the decline of the IR camera cost curve. We present a new short-wave IR (SWIR) camera; 640x512 pixel InGaAs uncooled system that is high sensitivity low noise (<50e-), high dynamic range (100 dB), high-frame rates (> 500 frames per second (FPS)) at full resolution, and low power consumption (< 1 W) in a compact system. This camera paves the way towards mass market adoption by not only demonstrating high-performance IR imaging capability value add demanded by military and industrial application, but also illuminates a path towards justifiable price points essential for consumer facing application industries such as automotive, medical, and security imaging adoption. Among the strategic options presented include new sensor manufacturing technologies that scale favorably towards automation, multi-focal plane array compatible readout electronics, and dense or ultra-small pixel pitch devices.
VLSI design of lossless frame recompression using multi-orientation prediction
NASA Astrophysics Data System (ADS)
Lee, Yu-Hsuan; You, Yi-Lun; Chen, Yi-Guo
2016-01-01
Pursuing an experience of high-end visual quality drives human to demand a higher display resolution and a higher frame rate. Hence, a lot of powerful coding tools are aggregated together in emerging video coding standards to improve coding efficiency. This also makes video coding standards suffer from two design challenges: heavy computation and tremendous memory bandwidth. The first issue can be properly solved by a careful hardware architecture design with advanced semiconductor processes. Nevertheless, the second one becomes a critical design bottleneck for a modern video coding system. In this article, a lossless frame recompression using multi-orientation prediction technique is proposed to overcome this bottleneck. This work is realised into a silicon chip with the technology of TSMC 0.18 µm CMOS process. Its encoding capability can reach full-HD (1920 × 1080)@48 fps. The chip power consumption is 17.31 mW@100 MHz. Core area and chip area are 0.83 × 0.83 mm2 and 1.20 × 1.20 mm2, respectively. Experiment results demonstrate that this work exhibits an outstanding performance on lossless compression ratio with a competitive hardware performance.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Iverson, Adam; Carlson, Carl; Young, Jason
2013-07-08
The diagnostic needs of any dynamic loading platform present unique technical challenges that must be addressed in order to accurately measure in situ material properties in an extreme environment. The IMPULSE platform (IMPact system for Ultrafast Synchrotron Experiments) at the Advanced Photon Source (APS) is no exception and, in fact, may be more challenging, as the imaging diagnostics must be synchronized to both the experiment and the 60 ps wide x-ray bunches produced at APS. The technical challenges of time-resolved x-ray diffraction imaging and high-resolution multi-frame phase contrast imaging (PCI) are described in this paper. Example data from recent IMPULSEmore » experiments are shown to illustrate the advances and evolution of these diagnostics with a focus on comparing the performance of two intensified CCD cameras and their suitability for multi-frame PCI. The continued development of these diagnostics is fundamentally important to IMPULSE and many other loading platforms and will benefit future facilities such as the Dynamic Compression Sector at APS and MaRIE at Los Alamos National Laboratory.« less
Color Image Processing and Object Tracking System
NASA Technical Reports Server (NTRS)
Klimek, Robert B.; Wright, Ted W.; Sielken, Robert S.
1996-01-01
This report describes a personal computer based system for automatic and semiautomatic tracking of objects on film or video tape, developed to meet the needs of the Microgravity Combustion and Fluids Science Research Programs at the NASA Lewis Research Center. The system consists of individual hardware components working under computer control to achieve a high degree of automation. The most important hardware components include 16-mm and 35-mm film transports, a high resolution digital camera mounted on a x-y-z micro-positioning stage, an S-VHS tapedeck, an Hi8 tapedeck, video laserdisk, and a framegrabber. All of the image input devices are remotely controlled by a computer. Software was developed to integrate the overall operation of the system including device frame incrementation, grabbing of image frames, image processing of the object's neighborhood, locating the position of the object being tracked, and storing the coordinates in a file. This process is performed repeatedly until the last frame is reached. Several different tracking methods are supported. To illustrate the process, two representative applications of the system are described. These applications represent typical uses of the system and include tracking the propagation of a flame front and tracking the movement of a liquid-gas interface with extremely poor visibility.
Hybrid parallel computing architecture for multiview phase shifting
NASA Astrophysics Data System (ADS)
Zhong, Kai; Li, Zhongwei; Zhou, Xiaohui; Shi, Yusheng; Wang, Congjun
2014-11-01
The multiview phase-shifting method shows its powerful capability in achieving high resolution three-dimensional (3-D) shape measurement. Unfortunately, this ability results in very high computation costs and 3-D computations have to be processed offline. To realize real-time 3-D shape measurement, a hybrid parallel computing architecture is proposed for multiview phase shifting. In this architecture, the central processing unit can co-operate with the graphic processing unit (GPU) to achieve hybrid parallel computing. The high computation cost procedures, including lens distortion rectification, phase computation, correspondence, and 3-D reconstruction, are implemented in GPU, and a three-layer kernel function model is designed to simultaneously realize coarse-grained and fine-grained paralleling computing. Experimental results verify that the developed system can perform 50 fps (frame per second) real-time 3-D measurement with 260 K 3-D points per frame. A speedup of up to 180 times is obtained for the performance of the proposed technique using a NVIDIA GT560Ti graphics card rather than a sequential C in a 3.4 GHZ Inter Core i7 3770.
Force production of a hovering hummingbird
NASA Astrophysics Data System (ADS)
Luo, Haoxiang; Song, Jialei; Hedrick, Tyson
2013-11-01
A three-dimensional numerical study is performed for a hovering Ruby-throated hummingbird (Archilochus colubris) based on an immersed-boundary method. To accurately model the unsteady aerodynamics, realistic 3D wing kinematics is reconstructed from high-speed images of the wing motion filmed at 1000 frames per second, resulting in 25 frames per flapping cycle. A high-resolution grid is employed to resolve the vortices shed from the wing. The results are validated by comparing the spanwise vorticity and circulation with the previous PIV data and also by calculating the average lift. The force production shows significant asymmetry with the downstroke producing lift 2.6 times as high as the upstroke, despite a nearly horizontal stroke plane. The total power consumption is around 55 W/kg, which is twice of previous estimate. In this presentation, we will discuss several mechanisms that lead to the force asymmetry, including the drag-based lift and the leading-edge vortex behavior. We will also address the role of wing-wake interaction, which appears to be different for the hummingbird than some of the insects such as fruit flies. Supported by NSF (No. CBET-0954381).
Tsujino, Soichiro; Tomizaki, Takashi
2016-05-06
Increasing the data acquisition rate of X-ray diffraction images for macromolecular crystals at room temperature at synchrotrons has the potential to significantly accelerate both structural analysis of biomolecules and structure-based drug developments. Using lysozyme model crystals, we demonstrated the rapid acquisition of X-ray diffraction datasets by combining a high frame rate pixel array detector with ultrasonic acoustic levitation of protein crystals in liquid droplets. The rapid spinning of the crystal within a levitating droplet ensured an efficient sampling of the reciprocal space. The datasets were processed with a program suite developed for serial femtosecond crystallography (SFX). The structure, which was solved by molecular replacement, was found to be identical to the structure obtained by the conventional oscillation method for up to a 1.8-Å resolution limit. In particular, the absence of protein crystal damage resulting from the acoustic levitation was carefully established. These results represent a key step towards a fully automated sample handling and measurement pipeline, which has promising prospects for a high acquisition rate and high sample efficiency for room temperature X-ray crystallography.
Ultrasonic acoustic levitation for fast frame rate X-ray protein crystallography at room temperature
NASA Astrophysics Data System (ADS)
Tsujino, Soichiro; Tomizaki, Takashi
2016-05-01
Increasing the data acquisition rate of X-ray diffraction images for macromolecular crystals at room temperature at synchrotrons has the potential to significantly accelerate both structural analysis of biomolecules and structure-based drug developments. Using lysozyme model crystals, we demonstrated the rapid acquisition of X-ray diffraction datasets by combining a high frame rate pixel array detector with ultrasonic acoustic levitation of protein crystals in liquid droplets. The rapid spinning of the crystal within a levitating droplet ensured an efficient sampling of the reciprocal space. The datasets were processed with a program suite developed for serial femtosecond crystallography (SFX). The structure, which was solved by molecular replacement, was found to be identical to the structure obtained by the conventional oscillation method for up to a 1.8-Å resolution limit. In particular, the absence of protein crystal damage resulting from the acoustic levitation was carefully established. These results represent a key step towards a fully automated sample handling and measurement pipeline, which has promising prospects for a high acquisition rate and high sample efficiency for room temperature X-ray crystallography.
Ultrasonic acoustic levitation for fast frame rate X-ray protein crystallography at room temperature
Tsujino, Soichiro; Tomizaki, Takashi
2016-01-01
Increasing the data acquisition rate of X-ray diffraction images for macromolecular crystals at room temperature at synchrotrons has the potential to significantly accelerate both structural analysis of biomolecules and structure-based drug developments. Using lysozyme model crystals, we demonstrated the rapid acquisition of X-ray diffraction datasets by combining a high frame rate pixel array detector with ultrasonic acoustic levitation of protein crystals in liquid droplets. The rapid spinning of the crystal within a levitating droplet ensured an efficient sampling of the reciprocal space. The datasets were processed with a program suite developed for serial femtosecond crystallography (SFX). The structure, which was solved by molecular replacement, was found to be identical to the structure obtained by the conventional oscillation method for up to a 1.8-Å resolution limit. In particular, the absence of protein crystal damage resulting from the acoustic levitation was carefully established. These results represent a key step towards a fully automated sample handling and measurement pipeline, which has promising prospects for a high acquisition rate and high sample efficiency for room temperature X-ray crystallography. PMID:27150272
Real-time terahertz near-field microscope.
Blanchard, F; Doi, A; Tanaka, T; Hirori, H; Tanaka, H; Kadoya, Y; Tanaka, K
2011-04-25
We report a terahertz near-field microscope with a high dynamic range that can capture images of a 370 x 740 μm2 area at 35 frames per second. We achieve high spatial resolution (14 μm corresponding to λ/30 for a center frequency at 0.7 THz) on a large area by combining two novel techniques: terahertz generation by tilted-pulse-front excitation and electro-optic balanced imaging detection using a thin crystal. To demonstrate the microscope capability, we reveal the field enhancement at the gap position of a dipole antenna after the irradiation of a terahertz pulse.
Birgiolas, Justas; Jernigan, Christopher M.; Gerkin, Richard C.; Smith, Brian H.; Crook, Sharon M.
2017-01-01
Many scientifically and agriculturally important insects use antennae to detect the presence of volatile chemical compounds and extend their proboscis during feeding. The ability to rapidly obtain high-resolution measurements of natural antenna and proboscis movements and assess how they change in response to chemical, developmental, and genetic manipulations can aid the understanding of insect behavior. By extending our previous work on assessing aggregate insect swarm or animal group movements from natural and laboratory videos using the video analysis software SwarmSight, we developed a novel, free, and open-source software module, SwarmSight Appendage Tracking (SwarmSight.org) for frame-by-frame tracking of insect antenna and proboscis positions from conventional web camera videos using conventional computers. The software processes frames about 120 times faster than humans, performs at better than human accuracy, and, using 30 frames per second (fps) videos, can capture antennal dynamics up to 15 Hz. The software was used to track the antennal response of honey bees to two odors and found significant mean antennal retractions away from the odor source about 1 s after odor presentation. We observed antenna position density heat map cluster formation and cluster and mean angle dependence on odor concentration. PMID:29364251
NASA Astrophysics Data System (ADS)
Li, Jia; Tian, Yonghong; Gao, Wen
2008-01-01
In recent years, the amount of streaming video has grown rapidly on the Web. Often, retrieving these streaming videos offers the challenge of indexing and analyzing the media in real time because the streams must be treated as effectively infinite in length, thus precluding offline processing. Generally speaking, captions are important semantic clues for video indexing and retrieval. However, existing caption detection methods often have difficulties to make real-time detection for streaming video, and few of them concern on the differentiation of captions from scene texts and scrolling texts. In general, these texts have different roles in streaming video retrieval. To overcome these difficulties, this paper proposes a novel approach which explores the inter-frame correlation analysis and wavelet-domain modeling for real-time caption detection in streaming video. In our approach, the inter-frame correlation information is used to distinguish caption texts from scene texts and scrolling texts. Moreover, wavelet-domain Generalized Gaussian Models (GGMs) are utilized to automatically remove non-text regions from each frame and only keep caption regions for further processing. Experiment results show that our approach is able to offer real-time caption detection with high recall and low false alarm rate, and also can effectively discern caption texts from the other texts even in low resolutions.
Coregistration of high-resolution Mars orbital images
NASA Astrophysics Data System (ADS)
Sidiropoulos, Panagiotis; Muller, Jan-Peter
2015-04-01
The systematic orbital imaging of the Martian surface started 4 decades ago from NASA's Viking Orbiter 1 & 2 missions, which were launched in August 1975, and acquired orbital images of the planet between 1976 and 1980. The result of this reconnaissance was the first medium-resolution (i.e. ≤ 300m/pixel) global map of Mars, as well as a variety of high-resolution images (reaching up to 8m/pixel) of special regions of interest. Over the last two decades NASA has sent 3 more spacecraft with onboard instruments for high-resolution orbital imaging: Mars Global Surveyor (MGS) having onboard the Mars Orbital Camera - Narrow Angle (MOC-NA), Mars Odyssey having onboard the Thermal Emission Imaging System - Visual (THEMIS-VIS) and the Mars Reconnaissance Orbiter (MRO) having on board two distinct high-resolution cameras, Context Camera (CTX) and High-Resolution Imaging Science Experiment (HiRISE). Moreover, ESA has the multispectral High resolution Stereo Camera (HRSC) onboard ESA's Mars Express with resolution up to 12.5m since 2004. Overall, this set of cameras have acquired more than 400,000 high-resolution images, i.e. with resolution better than 100m and as fine as 25 cm/pixel. Notwithstanding the high spatial resolution of the available NASA orbital products, their accuracy of areo-referencing is often very poor. As a matter of fact, due to pointing inconsistencies, usually form errors in roll attitude, the acquired products may actually image areas tens of kilometers far away from the point that they are supposed to be looking at. On the other hand, since 2004, the ESA Mars Express has been acquiring stereo images through the High Resolution Stereo Camera (HRSC), with resolution that is usually 12.5-25 metres per pixel. The achieved coverage is more than 64% for images with resolution finer than 20 m/pixel, while for ~40% of Mars, Digital Terrain Models (DTMs) have been produced with are co-registered with MOLA [Gwinner et al., 2010]. The HRSC images and DTMs represent the best available 3D reference frame for Mars showing co-registration with MOLA<25m (loc.cit.). In our work, the reference generated by HRSC terrain corrected orthorectified images is used as a common reference frame to co-register all available high-resolution orbital NASA products into a common 3D coordinate system, thus allowing the examination of the changes that happen on the surface of Mars over time (such as seasonal flows [McEwen et al., 2011] or new impact craters [Byrne, et al., 2009]). In order to accomplish such a tedious manual task, we have developed an automatic co-registration pipeline that produces orthorectified versions of the NASA images in realistic time (i.e. from ~15 minutes to 10 hours per image depending on size). In the first step of this pipeline, tie-points are extracted from the target NASA image and the reference HRSC image or image mosaic. Subsequently, the HRSC areo-reference information is used to transform the HRSC tie-points pixel coordinates into 3D "world" coordinates. This way, a correspondence between the pixel coordinates of the target NASA image and the 3D "world" coordinates is established for each tie-point. This set of correspondences is used to estimate a non-rigid, 3D to 2D transformation model, which transforms the target image into the HRSC reference coordinate system. Finally, correlation of the transformed target image and the HRSC image is employed to fine-tune the orthorectification results, thus generating results with sub-pixel accuracy. This method, which has been proven to be accurate, robust to resolution differences and reliable when dealing with partially degraded data and fast, will be presented, along with some example co-registration results that have been achieved by using it. Acknowledgements: The research leading to these results has received partial funding from the STFC "MSSL Consolidated Grant" ST/K000977/1 and partial support from the European Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement n° 607379. References: [1] K. F. Gwinner, et al. (2010) Topography of Mars from global mapping by HRSC high-resolution digital terrain models and orthoimages: characteristics and performance. Earth and Planetary Science Letters 294, 506-519, doi:10.1016/j.epsl.2009.11.007. [2] A. McEwen, et al. (2011) Seasonal flows on warm martian slopes. Science , 333 (6043): 740-743. [3] S. Byrne, et al. (2009) Distribution of mid-latitude ground ice on mars from new impact craters. Science, 325(5948):1674-1676.
Noise reduction in single time frame optical DNA maps
Müller, Vilhelm; Westerlund, Fredrik
2017-01-01
In optical DNA mapping technologies sequence-specific intensity variations (DNA barcodes) along stretched and stained DNA molecules are produced. These “fingerprints” of the underlying DNA sequence have a resolution of the order one kilobasepairs and the stretching of the DNA molecules are performed by surface adsorption or nano-channel setups. A post-processing challenge for nano-channel based methods, due to local and global random movement of the DNA molecule during imaging, is how to align different time frames in order to produce reproducible time-averaged DNA barcodes. The current solutions to this challenge are computationally rather slow. With high-throughput applications in mind, we here introduce a parameter-free method for filtering a single time frame noisy barcode (snap-shot optical map), measured in a fraction of a second. By using only a single time frame barcode we circumvent the need for post-processing alignment. We demonstrate that our method is successful at providing filtered barcodes which are less noisy and more similar to time averaged barcodes. The method is based on the application of a low-pass filter on a single noisy barcode using the width of the Point Spread Function of the system as a unique, and known, filtering parameter. We find that after applying our method, the Pearson correlation coefficient (a real number in the range from -1 to 1) between the single time-frame barcode and the time average of the aligned kymograph increases significantly, roughly by 0.2 on average. By comparing to a database of more than 3000 theoretical plasmid barcodes we show that the capabilities to identify plasmids is improved by filtering single time-frame barcodes compared to the unfiltered analogues. Since snap-shot experiments and computational time using our method both are less than a second, this study opens up for high throughput optical DNA mapping with improved reproducibility. PMID:28640821
A high-frequency sonar for profiling small-scale subaqueous bedforms
Dingler, J.R.; Boylls, J.C.; Lowe, R.L.
1977-01-01
A high-resolution ultrasonic profiler has been developed which permits both laboratory and field studies of small-scale subaqueous bedforms. The device uses a 2.5-cm diameter piezoelectric ceramic crystal pulsed at a frequency of 4.5 MHz to obtain vertical accuracy and resolution of at least 1 mm. Compared to other small-scale profiling methods, this ultrasonic technique profiles the bottom more accurately and more rapidly without disturbing the bedforms. These characteristics are vital in wave-dominated nearshore zones where oscillatory flow and low visibility for the most part have stymied detailed bedform studies. In the laboratory the transducer is mounted directly to an instrument carriage. For field work the transducer housing is mounted in a 2 m long aluminum frame which is situated and operated by scuba divers. Observations using the device include ripple geometry and migration, the suspension height of sand during sheet flow, and long-term erosion/deposition at a point. ?? 1977.
13C and 1H NMR (Nuclear Magnetic Resonance) studies of solid polyolefines
NASA Technical Reports Server (NTRS)
Cudby, M. E. A.; Harris, R. K.; Metcalfe, K.; Packer, K. J.; Smith, P. W. R.
1983-01-01
The basis of H-1 and C-13 high-resolution NMR investigations of solid polymers is outlined. The C-13 NMR spectra of solid syndiotactic and isotactic polypropene are discussed and their interpretation in terms of conformation and chain-packing effects are reviewed. The effects of decreasing temperature on the C-13 high-resolution spectrum of an annealed sample of isotactic polypropene is described and interpreted in terms of the crystal structure. The question of the proportion of the sample giving rise to C-13 signals is addressed and some results reported. The main cause for observing only part of the total sample is shown to be the H-1 rotating frame spin-lattice relaxation behavior. The H-1 spin-lattice relaxation and spectral characteristics of a number of polyolefin samples are summarized and the role of spin-diffusion discussed.
Fine-Scale Fluctuations in the Corona Observed with Hi-C
NASA Technical Reports Server (NTRS)
Winebarger, Amy; Schuler, Timothy
2013-01-01
The High Resolution Coronal Imager(HiC) flew aboard a NASA sounding rocket on 2012 July11 and captured roughly 345 s of high spatial and temporal resolution images of the solar corona in a narrowband 193 Angstrom channel. We have analyzed the fluctuations in intensity of Active Region11520.We selected events based on a lifetime greater than 11s (twoHiC frames)and intensities greater than a threshold determined from the average background intensity in a pixel and the photon and electronic noise. We find fluctuations occurring down to the smallest timescale(11s).Typical intensity fluctuations are 20% background intensity, while some events peaka t100%the background intensity.Generally the fluctuations are clustered in solar structures, particularly the moss.We interpret the fluctuations in the moss as indicative of heating events. We use the observed events to model the active region core.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nagel, S. R.; Chen, H.; Park, J.
Time resolved x-ray images with 7 ps resolution are recorded on relativistic short-pulse laser-plasma experiments using the dilation x-ray imager, a high-speed x-ray framing camera, sensitive to x-rays in the range of ≈1-17 keV. Furthermore, this capability enables a series of 2D x-ray images to be recorded at picosecond scales, which allows for the investigation of fast electron transport within the target with unprecedented temporal resolution. With an increase in the Kα-emission spot size over time we found that targets were thinner than the recirculation limit and is absent for thicker targets. Together with the observed polarization dependence of themore » spot size increase, this indicates that electron recirculation is relevant for the x-ray production in thin targets.« less
Nagel, S. R.; Chen, H.; Park, J.; ...
2017-04-04
Time resolved x-ray images with 7 ps resolution are recorded on relativistic short-pulse laser-plasma experiments using the dilation x-ray imager, a high-speed x-ray framing camera, sensitive to x-rays in the range of ≈1-17 keV. Furthermore, this capability enables a series of 2D x-ray images to be recorded at picosecond scales, which allows for the investigation of fast electron transport within the target with unprecedented temporal resolution. With an increase in the Kα-emission spot size over time we found that targets were thinner than the recirculation limit and is absent for thicker targets. Together with the observed polarization dependence of themore » spot size increase, this indicates that electron recirculation is relevant for the x-ray production in thin targets.« less
NASA Astrophysics Data System (ADS)
Bowen, Spencer L.; Byars, Larry G.; Michel, Christian J.; Chonde, Daniel B.; Catana, Ciprian
2013-10-01
Kinetic parameters estimated from dynamic 18F-fluorodeoxyglucose (18F-FDG) PET acquisitions have been used frequently to assess brain function in humans. Neglecting partial volume correction (PVC) for a dynamic series has been shown to produce significant bias in model estimates. Accurate PVC requires a space-variant model describing the reconstructed image spatial point spread function (PSF) that accounts for resolution limitations, including non-uniformities across the field of view due to the parallax effect. For ordered subsets expectation maximization (OSEM), image resolution convergence is local and influenced significantly by the number of iterations, the count density, and background-to-target ratio. As both count density and background-to-target values for a brain structure can change during a dynamic scan, the local image resolution may also concurrently vary. When PVC is applied post-reconstruction the kinetic parameter estimates may be biased when neglecting the frame-dependent resolution. We explored the influence of the PVC method and implementation on kinetic parameters estimated by fitting 18F-FDG dynamic data acquired on a dedicated brain PET scanner and reconstructed with and without PSF modelling in the OSEM algorithm. The performance of several PVC algorithms was quantified with a phantom experiment, an anthropomorphic Monte Carlo simulation, and a patient scan. Using the last frame reconstructed image only for regional spread function (RSF) generation, as opposed to computing RSFs for each frame independently, and applying perturbation geometric transfer matrix PVC with PSF based OSEM produced the lowest magnitude bias kinetic parameter estimates in most instances, although at the cost of increased noise compared to the PVC methods utilizing conventional OSEM. Use of the last frame RSFs for PVC with no PSF modelling in the OSEM algorithm produced the lowest bias in cerebral metabolic rate of glucose estimates, although by less than 5% in most cases compared to the other PVC methods. The results indicate that the PVC implementation and choice of PSF modelling in the reconstruction can significantly impact model parameters.
Bowen, Spencer L; Byars, Larry G; Michel, Christian J; Chonde, Daniel B; Catana, Ciprian
2013-10-21
Kinetic parameters estimated from dynamic (18)F-fluorodeoxyglucose ((18)F-FDG) PET acquisitions have been used frequently to assess brain function in humans. Neglecting partial volume correction (PVC) for a dynamic series has been shown to produce significant bias in model estimates. Accurate PVC requires a space-variant model describing the reconstructed image spatial point spread function (PSF) that accounts for resolution limitations, including non-uniformities across the field of view due to the parallax effect. For ordered subsets expectation maximization (OSEM), image resolution convergence is local and influenced significantly by the number of iterations, the count density, and background-to-target ratio. As both count density and background-to-target values for a brain structure can change during a dynamic scan, the local image resolution may also concurrently vary. When PVC is applied post-reconstruction the kinetic parameter estimates may be biased when neglecting the frame-dependent resolution. We explored the influence of the PVC method and implementation on kinetic parameters estimated by fitting (18)F-FDG dynamic data acquired on a dedicated brain PET scanner and reconstructed with and without PSF modelling in the OSEM algorithm. The performance of several PVC algorithms was quantified with a phantom experiment, an anthropomorphic Monte Carlo simulation, and a patient scan. Using the last frame reconstructed image only for regional spread function (RSF) generation, as opposed to computing RSFs for each frame independently, and applying perturbation geometric transfer matrix PVC with PSF based OSEM produced the lowest magnitude bias kinetic parameter estimates in most instances, although at the cost of increased noise compared to the PVC methods utilizing conventional OSEM. Use of the last frame RSFs for PVC with no PSF modelling in the OSEM algorithm produced the lowest bias in cerebral metabolic rate of glucose estimates, although by less than 5% in most cases compared to the other PVC methods. The results indicate that the PVC implementation and choice of PSF modelling in the reconstruction can significantly impact model parameters.
Real-time haptic cutting of high-resolution soft tissues.
Wu, Jun; Westermann, Rüdiger; Dick, Christian
2014-01-01
We present our systematic efforts in advancing the computational performance of physically accurate soft tissue cutting simulation, which is at the core of surgery simulators in general. We demonstrate a real-time performance of 15 simulation frames per second for haptic soft tissue cutting of a deformable body at an effective resolution of 170,000 finite elements. This is achieved by the following innovative components: (1) a linked octree discretization of the deformable body, which allows for fast and robust topological modifications of the simulation domain, (2) a composite finite element formulation, which thoroughly reduces the number of simulation degrees of freedom and thus enables to carefully balance simulation performance and accuracy, (3) a highly efficient geometric multigrid solver for solving the linear systems of equations arising from implicit time integration, (4) an efficient collision detection algorithm that effectively exploits the composition structure, and (5) a stable haptic rendering algorithm for computing the feedback forces. Considering that our method increases the finite element resolution for physically accurate real-time soft tissue cutting simulation by an order of magnitude, our technique has a high potential to significantly advance the realism of surgery simulators.
Automatic Near-Real-Time Image Processing Chain for Very High Resolution Optical Satellite Data
NASA Astrophysics Data System (ADS)
Ostir, K.; Cotar, K.; Marsetic, A.; Pehani, P.; Perse, M.; Zaksek, K.; Zaletelj, J.; Rodic, T.
2015-04-01
In response to the increasing need for automatic and fast satellite image processing SPACE-SI has developed and implemented a fully automatic image processing chain STORM that performs all processing steps from sensor-corrected optical images (level 1) to web-delivered map-ready images and products without operator's intervention. Initial development was tailored to high resolution RapidEye images, and all crucial and most challenging parts of the planned full processing chain were developed: module for automatic image orthorectification based on a physical sensor model and supported by the algorithm for automatic detection of ground control points (GCPs); atmospheric correction module, topographic corrections module that combines physical approach with Minnaert method and utilizing anisotropic illumination model; and modules for high level products generation. Various parts of the chain were implemented also for WorldView-2, THEOS, Pleiades, SPOT 6, Landsat 5-8, and PROBA-V. Support of full-frame sensor currently in development by SPACE-SI is in plan. The proposed paper focuses on the adaptation of the STORM processing chain to very high resolution multispectral images. The development concentrated on the sub-module for automatic detection of GCPs. The initially implemented two-step algorithm that worked only with rasterized vector roads and delivered GCPs with sub-pixel accuracy for the RapidEye images, was improved with the introduction of a third step: super-fine positioning of each GCP based on a reference raster chip. The added step exploits the high spatial resolution of the reference raster to improve the final matching results and to achieve pixel accuracy also on very high resolution optical satellite data.
Geologic map of the Galaxias quadrangle (MTM 35217) of Mars
De Hon, Rene A.; Mouginis-Mark, Peter J.; Brick, Eugene E.
1999-01-01
The Galaxias region (MTM 35217) is one of a series of 1:500,000-scale science study areas on Mars sponsored by NASA's Planetary Geology and Geophysics Program. Situated near the northern limit of lava flows associated with Elysium Mons, this region includes a mixture of volcanic and nonvolcanic terrains. The region is also of interest for the fluvial systems that originate along the distal margins of the Elysium lava flows. Resolution of Viking Orbiter images used to prepare the base map ranges from 40 to 160 m/pixel. High-resolution frames (40 to 80 m/pixel) are found in the southeastern part of the map area and along the north edge of the quadrangle, but over half the quadrangle is included in medium-resolution frames (150 m/pixel). Two 8 m/pixel, very high resolution scenes are available (see fig. 1). Interpretation is complicated by variable resolution and sun angles that vary from east to west illumination on different images. Mapping methods and principles are adapted from those developed for lunar photogeologic mapping by Shoemaker and Hackman (1962), refined by Wilhelms (1972), and successfully applied by many workers to a variety of planetary surfaces. Mapping units are distinguished by topography and texture and are ranked by relative age on the basis of superposition and transection relations. Material units are assigned to time-stratigraphic systems defined by Scott and Carr (1978) and Tanaka (1986). This area is included within earlier maps that used Mariner 9 images at 1:5,000,000 scale (Elston, 1979) and globally at 1:25,000,000 scale (Scott and Carr, 1978). Regional maps based on the much higher resolutions of Viking Orbiter allowed more detailed discrimination of materials by Greeley and Guest (1987) at 1:15,000,000 scale and Tanaka and others (1992) at 1:5,000,000 scale. Some map units on this 1:500,000-scale map correspond to, or are partially equivalent to, units on the larger scale maps of Greeley and Guest (1987) and Tanaka and others (1992). Established terminology is used where feasible, but the scale of this map requires that some new units be introduced and that some previous terminology be redefined. Photogeologic methods are limited; therefore, more than one geologic explanation is given for some material units that do not readily lend themselves to an unequivocal interpretation.
High-Speed PLIF Imaging of Hypersonic Transition over Discrete Cylindrical Roughness
NASA Technical Reports Server (NTRS)
Danehy, P. M.; Ivey, C. B.; Inman, J. A.; Bathel, B. F.; Jones, S. B.; McCrea, A. C.; Jiang, N.; Webster, M.; Lempert, W.; Miller, J.;
2010-01-01
In two separate test entries, advanced laser-based instrumentation has been developed and applied to visualize the hypersonic flow over cylindrical protrusions on a flat plate. Upstream of these trips, trace quantities of nitric oxide (NO) were seeded into the boundary layer. The protuberances were sized to force laminar-to-turbulent boundary layer transition. In the first test, a 10-Hz nitric oxide planar laser-induced fluorescence (NO PLIF) flow visualization system was used to provide wide-field-of-view, high-resolution images of the flowfield. The images had sub-microsecond time resolution. However these images, obtained with a time separation of 0.1 sec, were uncorrelated with each other. Fluorescent oil-flow visualizations were also obtained during this test. In the second experiment, a laser and camera system capable of acquiring NO PLIF measurements at 1 million frames per second (1 MHz) was used. This system had lower spatial resolution, and a smaller field of view, but the images were time correlated so that the development of the flow structures could be observed in time.
Coates, Colin G; Denvir, Donal J; McHale, Noel G; Thornbury, Keith D; Hollywood, Mark A
2004-01-01
The back-illuminated electron multiplying charge-coupled device (EMCCD) camera is having a profound influence on the field of low-light dynamic cellular microscopy, combining highest possible photon collection efficiency with the ability to virtually eliminate the readout noise detection limit. We report here the use of this camera, in 512 x 512 frame-transfer chip format at 10-MHz pixel readout speed, in optimizing a demanding ultra-low-light intracellular calcium flux microscopy setup. The arrangement employed includes a spinning confocal Nipkow disk, which, while facilitating the need to both generate images at very rapid frame rates and minimize background photons, yields very weak signals. The challenge for the camera lies not just in detecting as many of these scarce photons as possible, but also in operating at a frame rate that meets the temporal resolution requirements of many low-light microscopy approaches, a particular demand of smooth muscle calcium flux microscopy. Results presented illustrate both the significant sensitivity improvement offered by this technology over the previous standard in ultra-low-light CCD detection, the GenIII+intensified charge-coupled device (ICCD), and also portray the advanced temporal and spatial resolution capabilities of the EMCCD. Copyright 2004 Society of Photo-Optical Instrumentation Engineers.
Reif, Roberto; Baran, Utku; Wang, Ruikang K
2014-07-01
Optical coherence tomography (OCT) is a technique that allows for the three-dimensional (3D) imaging of small volumes of tissue (a few millimeters) with high resolution (∼10 μm). Optical microangiography (OMAG) is a method of processing OCT data, which allows for the extraction of the tissue vasculature with capillary resolution from the OCT images. Cross-sectional B-frame OMAG images present the location of the patent blood vessels; however, the signal-to-noise-ratio of these images can be affected by several factors such as the quality of the OCT system and the tissue motion artifact. This background noise can appear in the en face projection view image. In this work we propose to develop a binary mask that can be applied on the cross-sectional B-frame OMAG images, which will reduce the background noise while leaving the signal from the blood vessels intact. The mask is created by using a naïve Bayes (NB) classification algorithm trained with a gold standard image which is manually segmented by an expert. The masked OMAG images present better contrast for binarizing the image and quantifying the result without the influence of noise. The results are compared with a previously developed frequency rejection filter (FRF) method which is applied on the en face projection view image. It is demonstrated that both the NB and FRF methods provide similar vessel length fractions. The advantage of the NB method is that the results are applicable in 3D and that its use is not limited to periodic motion artifacts.
3-D Velocimetry of Strombolian Explosions
NASA Astrophysics Data System (ADS)
Taddeucci, J.; Gaudin, D.; Orr, T. R.; Scarlato, P.; Houghton, B. F.; Del Bello, E.
2014-12-01
Using two synchronized high-speed cameras we were able to reconstruct the three-dimensional displacement and velocity field of bomb-sized pyroclasts in Strombolian explosions at Stromboli Volcano. Relatively low-intensity Strombolian-style activity offers a rare opportunity to observe volcanic processes that remain hidden from view during more violent explosive activity. Such processes include the ejection and emplacement of bomb-sized clasts along pure or drag-modified ballistic trajectories, in-flight bomb collision, and gas liberation dynamics. High-speed imaging of Strombolian activity has already opened new windows for the study of the abovementioned processes, but to date has only utilized two-dimensional analysis with limited motion detection and ability to record motion towards or away from the observer. To overcome this limitation, we deployed two synchronized high-speed video cameras at Stromboli. The two cameras, located sixty meters apart, filmed Strombolian explosions at 500 and 1000 frames per second and with different resolutions. Frames from the two cameras were pre-processed and combined into a single video showing frames alternating from one to the other camera. Bomb-sized pyroclasts were then manually identified and tracked in the combined video, together with fixed reference points located as close as possible to the vent. The results from manual tracking were fed to a custom software routine that, knowing the relative position of the vent and cameras, and the field of view of the latter, provided the position of each bomb relative to the reference points. By tracking tens of bombs over five to ten frames at different intervals during one explosion, we were able to reconstruct the three-dimensional evolution of the displacement and velocity fields of bomb-sized pyroclasts during individual Strombolian explosions. Shifting jet directivity and dispersal angle clearly appear from the three-dimensional analysis.
High resolution SETI: Experiences and prospects
NASA Astrophysics Data System (ADS)
Horowitz, Paul; Clubok, Ken
Megachannel spectroscopy with sub-Hertz resolution constitutes an attractive strategy for a microwave search for extraterrestrial intelligence (SETI), assuming the transmission of a narrowband radiofrequency beacon. Such resolution matches the properties of the interstellar medium, and the necessary Doppler corrections provide a high degree of interference rejection. We have constructed a frequency-agile receiver with an FFT-based 8 megachannel digital spectrum analyzer, on-line signal recognition, and multithreshold archiving. We are using it to conduct a meridian transit search of the northern sky at the Harvard-Smithsonian 26-m antenna, with a second identical system scheduled to begin observations in Argentina this month. Successive 400 kHz spectra, at 0.05 Hz resolution, are searched for features characteristic of an intentional narrowband beacon transmission. These spectra are centered on guessable frequencies (such as λ21 cm), referenced successively to the local standard of rest, the galactic barycenter, and the cosmic blackbody rest frame. This search has rejected interference admirably, but is greatly limited both in total frequency coverage and sensitivity to signals other than carriers. We summarize five years of high resolution SETI at Harvard, in the context of answering the questions "How useful is narrowband SETI, how serious are its limitations, what can be done to circumvent them, and in what direction should SETI evolve?" Increasingly powerful signal processing hardware, combined with ever-higher memory densities, are particularly relevant, permitting the construction of compact and affordable gigachannel spectrum analyzers covering hundreds of megahertz of instantaneous bandwidth.
High-speed uncooled MWIR hostile fire indication sensor
NASA Astrophysics Data System (ADS)
Zhang, L.; Pantuso, F. P.; Jin, G.; Mazurenko, A.; Erdtmann, M.; Radhakrishnan, S.; Salerno, J.
2011-06-01
Hostile fire indication (HFI) systems require high-resolution sensor operation at extremely high speeds to capture hostile fire events, including rocket-propelled grenades, anti-aircraft artillery, heavy machine guns, anti-tank guided missiles and small arms. HFI must also be conducted in a waveband with large available signal and low background clutter, in particular the mid-wavelength infrared (MWIR). The shortcoming of current HFI sensors in the MWIR is the bandwidth of the sensor is not sufficient to achieve the required frame rate at the high sensor resolution. Furthermore, current HFI sensors require cryogenic cooling that contributes to size, weight, and power (SWAP) in aircraft-mounted applications where these factors are at a premium. Based on its uncooled photomechanical infrared imaging technology, Agiltron has developed a low-SWAP, high-speed MWIR HFI sensor that breaks the bandwidth bottleneck typical of current infrared sensors. This accomplishment is made possible by using a commercial-off-the-shelf, high-performance visible imager as the readout integrated circuit and physically separating this visible imager from the MWIR-optimized photomechanical sensor chip. With this approach, we have achieved high-resolution operation of our MWIR HFI sensor at 1000 fps, which is unprecedented for an uncooled infrared sensor. We have field tested our MWIR HFI sensor for detecting all hostile fire events mentioned above at several test ranges under a wide range of environmental conditions. The field testing results will be presented.
Development of a Dual-PIV system for high-speed flow applications
NASA Astrophysics Data System (ADS)
Schreyer, Anne-Marie; Lasserre, Jean J.; Dupont, Pierre
2015-10-01
A new Dual-particle image velocimetry (Dual-PIV) system for application in supersonic flows was developed. The system was designed for shock wave/turbulent boundary layer interactions with separation. This type of flow places demanding requirements on the system, from the large range of characteristic frequencies O(100 Hz-100 kHz) to spatial and temporal resolutions necessary for the measurement of turbulent quantities (Dolling in AIAA J 39(8):1517-1531, 2001; Dupont et al. in J Fluid Mech 559:255-277, 2006; Smits and Dussauge in Turbulent shear layers in supersonic flow, 2nd edn. Springer, New York, 2006). While classic PIV systems using high-resolution CCD sensors allow high spatial resolution, these systems cannot provide the required temporal resolution. Existing high-speed PIV systems provide temporal and CMOS sensor resolutions, and even laser pulse energies, that are not adapted to our needs. The only obvious solution allowing sufficiently high spatial resolution, access to high frequencies, and a high laser pulse energy is a multi-frame system: a Dual-PIV system, consisting of two synchronized PIV systems observing the same field of view, will give access to temporal characteristics of the flow. The key technology of our system is frequency-based image separation: two lasers of different wavelengths illuminate the field of view. The cross-pollution with laser light from the respective other branches was quantified during system validation. The overall system noise was quantified, and the prevailing error of only 2 % reflects the good spatial and temporal alignment. The quality of the measurement system is demonstrated with some results on a subsonic jet flow including the spatio-temporal inter-correlation functions between the systems. First measurements in a turbulent flat-plate boundary layer at Mach 2 show the same satisfactory data quality and are also presented and discussed.
Contrast-enhanced MR Angiography of the Abdomen with Highly Accelerated Acquisition Techniques
Mostardi, Petrice M.; Glockner, James F.; Young, Phillip M.
2011-01-01
Purpose: To demonstrate that highly accelerated (net acceleration factor [Rnet] ≥ 10) acquisition techniques can be used to generate three-dimensional (3D) subsecond timing images, as well as diagnostic-quality high-spatial-resolution contrast material–enhanced (CE) renal magnetic resonance (MR) angiograms with a single split dose of contrast material. Materials and Methods: All studies were approved by the institutional review board and were HIPAA compliant; written consent was obtained from all participants. Twenty-two studies were performed in 10 female volunteers (average age, 47 years; range, 27–62 years) and six patients with renovascular disease (three women; average age, 48 years; range, 37–68 years; three men; average age, 60 years; range, 50–67 years; composite average age, 54 years; range, 38–68 years). The two-part protocol consisted of a low-dose (2 mL contrast material) 3D timing image with approximate 1-second frame time, followed by a high-spatial-resolution (1.0–1.6-mm isotropic voxels) breath-hold 3D renal MR angiogram (18 mL) over the full abdominal field of view. Both acquisitions used two-dimensional (2D) sensitivity encoding acceleration factor (R) of eight and 2D homodyne (HD) acceleration (RHD) of 1.4–1.8 for Rnet = R · RHD of 10 or higher. Statistical analysis included determination of mean values and standard deviations of image quality scores performed by two experienced reviewers with use of eight evaluation criteria. Results: The 2-mL 3D time-resolved image successfully portrayed progressive arterial filling in all 22 studies and provided an anatomic overview of the vasculature. Successful timing was also demonstrated in that the renal MR angiogram showed adequate or excellent portrayal of the main renal arteries in 21 of 22 studies. Conclusion: Two-dimensional acceleration techniques with Rnet of 10 or higher can be used in CE MR angiography to acquire (a) a 3D image series with 1-second frame time, allowing accurate bolus timing, and (b) a high-spatial-resolution renal angiogram. © RSNA, 2011 Supplemental material: http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11110242/-/DC1 PMID:21900616
SuperHERO: Design of a New Hard X-Ray Focusing Telescope
NASA Technical Reports Server (NTRS)
Gaskin, Jessica; Elsner, Ronald; Ramsey, Brian; Wilson-Hodge, Colleen; Tennant, Allyn; Christe, Steven; Shih, Albert; Kiranmayee, Kilaru; Swartz, Douglas; Seller, Paul;
2015-01-01
SuperHERO is a hard x-ray (20-75 keV) balloon-borne telescope, currently in its proposal phase, that will utilize high angular-resolution grazing-incidence optics, coupled to novel CdTe multi-pixel, fine-pitch (250 micrometers) detectors. The high-resolution electroformed-nickel, grazing-incidence optics were developed at MSFC, and the detectors were developed at the Rutherford Appleton Laboratory in the UK, and are being readied for flight at GSFC. SuperHERO will use two active pointing systems; one for carrying out astronomical observations and another for solar observations during the same flight. The telescope will reside on a light-weight, carbon-composite structure that will integrate the Wallops Arc Second Pointer into its frame, for arcsecond or better pointing. This configuration will allow for Long Duration Balloon flights that can last up to 4 weeks. This next generation design, which is based on the High Energy Replicated Optics (HERO) and HERO to Explore the Sun (HEROES) payloads, will be discussed, with emphasis on the core telescope components.
Accurate 3D reconstruction by a new PDS-OSEM algorithm for HRRT
NASA Astrophysics Data System (ADS)
Chen, Tai-Been; Horng-Shing Lu, Henry; Kim, Hang-Keun; Son, Young-Don; Cho, Zang-Hee
2014-03-01
State-of-the-art high resolution research tomography (HRRT) provides high resolution PET images with full 3D human brain scanning. But, a short time frame in dynamic study causes many problems related to the low counts in the acquired data. The PDS-OSEM algorithm was proposed to reconstruct the HRRT image with a high signal-to-noise ratio that provides accurate information for dynamic data. The new algorithm was evaluated by simulated image, empirical phantoms, and real human brain data. Meanwhile, the time activity curve was adopted to validate a reconstructed performance of dynamic data between PDS-OSEM and OP-OSEM algorithms. According to simulated and empirical studies, the PDS-OSEM algorithm reconstructs images with higher quality, higher accuracy, less noise, and less average sum of square error than those of OP-OSEM. The presented algorithm is useful to provide quality images under the condition of low count rates in dynamic studies with a short scan time.
Transthoracic Ultrafast Doppler Imaging of Human Left Ventricular Hemodynamic Function
Osmanski, Bruno-Félix; Maresca, David; Messas, Emmanuel; Tanter, Mickael; Pernot, Mathieu
2016-01-01
Heart diseases can affect intraventricular blood flow patterns. Real-time imaging of blood flow patterns is challenging because it requires both a high frame rate and a large field of view. To date, standard Doppler techniques can only perform blood flow estimation with high temporal resolution within small regions of interest. In this work, we used ultrafast imaging to map in 2D human left ventricular blood flow patterns during the whole cardiac cycle. Cylindrical waves were transmitted at 4800 Hz with a transthoracic phased array probe to achieve ultrafast Doppler imaging of the left ventricle. The high spatio-temporal sampling of ultrafast imaging permits to rely on a much more effective wall filtering and to increase sensitivity when mapping blood flow patterns during the pre-ejection, ejection, early diastole, diastasis and late diastole phases of the heart cycle. The superior sensitivity and temporal resolution of ultrafast Doppler imaging makes it a promising tool for the noninvasive study of intraventricular hemodynamic function. PMID:25073134
Riffel, Philipp; Zoellner, Frank G; Budjan, Johannes; Grimm, Robert; Block, Tobias K; Schoenberg, Stefan O; Hausmann, Daniel
2016-11-01
The purpose of the present study was to evaluate a recently introduced technique for free-breathing dynamic contrast-enhanced renal magnetic resonance imaging (MRI) applying a combination of radial k-space sampling, parallel imaging, and compressed sensing. The technique allows retrospective reconstruction of 2 motion-suppressed sets of images from the same acquisition: one with lower temporal resolution but improved image quality for subjective image analysis, and one with high temporal resolution for quantitative perfusion analysis. In this study, 25 patients underwent a kidney examination, including a prototypical fat-suppressed, golden-angle radial stack-of-stars T1-weighted 3-dimensional spoiled gradient-echo examination (GRASP) performed after contrast agent administration during free breathing. Images were reconstructed at temporal resolutions of 55 spokes per frame (6.2 seconds) and 13 spokes per frame (1.5 seconds). The GRASP images were evaluated by 2 blinded radiologists. First, the reconstructions with low temporal resolution underwent subjective image analysis: the radiologists assessed the best arterial phase and the best renal phase and rated image quality score for each patient on a 5-point Likert-type scale.In addition, the diagnostic confidence was rated according to a 3-point Likert-type scale. Similarly, respiratory motion artifacts and streak artifacts were rated according to a 3-point Likert-type scale.Then, the reconstructions with high temporal resolution were analyzed with a voxel-by-voxel deconvolution approach to determine the renal plasma flow, and the results were compared with values reported in previous literature. Reader 1 and reader 2 rated the overall image quality score for the best arterial phase and the best renal phase with a median image quality score of 4 (good image quality) for both phases, respectively. A high diagnostic confidence (median score of 3) was observed. There were no respiratory motion artifacts in any of the patients. Streak artifacts were present in all of the patients, but did not compromise diagnostic image quality.The estimated renal plasma flow was slightly higher (295 ± 78 mL/100 mL per minute) than reported in previous MRI-based studies, but also closer to the physiologically expected value. Dynamic, motion-suppressed contrast-enhanced renal MRI can be performed in high diagnostic quality during free breathing using a combination of golden-angle radial sampling, parallel imaging, and compressed sensing. Both morphologic and quantitative functional information can be acquired within a single acquisition.
Characterization, adaptive traffic shaping, and multiplexing of real-time MPEG II video
NASA Astrophysics Data System (ADS)
Agrawal, Sanjay; Barry, Charles F.; Binnai, Vinay; Kazovsky, Leonid G.
1997-01-01
We obtain network traffic model for real-time MPEG-II encoded digital video by analyzing video stream samples from real-time encoders from NUKO Information Systems. MPEG-II sample streams include a resolution intensive movie, City of Joy, an action intensive movie, Aliens, a luminance intensive (black and white) movie, Road To Utopia, and a chrominance intensive (color) movie, Dick Tracy. From our analysis we obtain a heuristic model for the encoded video traffic which uses a 15-stage Markov process to model the I,B,P frame sequences within a group of pictures (GOP). A jointly-correlated Gaussian process is used to model the individual frame sizes. Scene change arrivals are modeled according to a gamma process. Simulations show that our MPEG-II traffic model generates, I,B,P frame sequences and frame sizes that closely match the sample MPEG-II stream traffic characteristics as they relate to latency and buffer occupancy in network queues. To achieve high multiplexing efficiency we propose a traffic shaping scheme which sets preferred 1-frame generation times among a group of encoders so as to minimize the overall variation in total offered traffic while still allowing the individual encoders to react to scene changes. Simulations show that our scheme results in multiplexing gains of up to 10% enabling us to multiplex twenty 6 Mbps MPEG-II video streams instead of 18 streams over an ATM/SONET OC3 link without latency or cell loss penalty. This scheme is due for a patent.
NASA Astrophysics Data System (ADS)
Ozeki, Yasuyuki; Otsuka, Yoichi; Sato, Shuya; Hashimoto, Hiroyuki; Umemura, Wataru; Sumimura, Kazuhiko; Nishizawa, Norihiko; Fukui, Kiichi; Itoh, Kazuyoshi
2013-02-01
We have developed a video-rate stimulated Raman scattering (SRS) microscope with frame-by-frame wavenumber tunability. The system uses a 76-MHz picosecond Ti:sapphire laser and a subharmonically synchronized, 38-MHz Yb fiber laser. The Yb fiber laser pulses are spectrally sliced by a fast wavelength-tunable filter, which consists of a galvanometer scanner, a 4-f optical system and a reflective grating. The spectral resolution of the filter is ~ 3 cm-1. The wavenumber was scanned from 2800 to 3100 cm-1 with an arbitrary waveform synchronized to the frame trigger. For imaging, we introduced a 8-kHz resonant scanner and a galvanometer scanner. We were able to acquire SRS images of 500 x 480 pixels at a frame rate of 30.8 frames/s. Then these images were processed by principal component analysis followed by a modified algorithm of independent component analysis. This algorithm allows blind separation of constituents with overlapping Raman bands from SRS spectral images. The independent component (IC) spectra give spectroscopic information, and IC images can be used to produce pseudo-color images. We demonstrate various label-free imaging modalities such as 2D spectral imaging of the rat liver, two-color 3D imaging of a vessel in the rat liver, and spectral imaging of several sections of intestinal villi in the mouse. Various structures in the tissues such as lipid droplets, cytoplasm, fibrous texture, nucleus, and water-rich region were successfully visualized.
Processing Near-Infrared Imagery of the Orion Heatshield During EFT-1 Hypersonic Reentry
NASA Technical Reports Server (NTRS)
Spisz, Thomas S.; Taylor, Jeff C.; Gibson, David M.; Kennerly, Steve; Osei-Wusu, Kwame; Horvath, Thomas J.; Schwartz, Richard J.; Tack, Steven; Bush, Brett C.; Oliver, A. Brandon
2016-01-01
The Scientifically Calibrated In-Flight Imagery (SCIFLI) team captured high-resolution, calibrated, near-infrared imagery of the Orion capsule during atmospheric reentry of the EFT-1 mission. A US Navy NP-3D aircraft equipped with a multi-band optical sensor package, referred to as Cast Glance, acquired imagery of the Orion capsule's heatshield during a period when Orion was slowing from approximately Mach 10 to Mach 7. The line-of-sight distance ranged from approximately 65 to 40 nmi. Global surface temperatures of the capsule's thermal heatshield derived from the near-infrared intensity measurements complemented the in-depth (embedded) thermocouple measurements. Moreover, these derived surface temperatures are essential to the assessment of the thermocouples' reliance on inverse heat transfer methods and material response codes to infer the surface temperature from the in-depth measurements. The paper describes the image processing challenges associated with a manually-tracked, high-angular rate air-to-air observation. Issues included management of significant frame-to-frame motions due to both tracking jerk and jitter as well as distortions due to atmospheric effects. Corrections for changing sky backgrounds (including some cirrus clouds), atmospheric attenuation, and target orientations and ranges also had to be made. The image processing goal is to reduce the detrimental effects due to motion (both sensor and capsule), vibration (jitter), and atmospherics for image quality improvement, without compromising the quantitative integrity of the data, especially local intensity (temperature) variations. The paper will detail the approach of selecting and utilizing only the highest quality images, registering several co-temporal image frames to a single image frame to the extent frame-to-frame distortions would allow, and then co-adding the registered frames to improve image quality and reduce noise. Using preflight calibration data, the registered and averaged infrared intensity images were converted to surface temperatures on the Orion capsule's heatshield. Temperature uncertainties will be discussed relative to uncertainties of surface emissivity and atmospheric transmission loss. Comparison of limited onboard surface thermocouple data to the image derived surface temperature will be presented.
Gray-scale transform and evaluation for digital x-ray chest images on CRT monitor
NASA Astrophysics Data System (ADS)
Furukawa, Isao; Suzuki, Junji; Ono, Sadayasu; Kitamura, Masayuki; Ando, Yutaka
1997-04-01
In this paper, an experimental evaluation of a super high definition (SHD) imaging system for digital x-ray chest images is presented. The SHD imaging system is proposed as a platform for integrating conventional image media. We are involved in the use of SHD images in the total digitizing of medical records that include chest x-rays and pathological microscopic images, both which demand the highest level of quality among the various types of medical images. SHD images use progressive scanning and have a spatial resolution of 2000 by 2000 pixels or more and a temporal resolution (frame rate) of 60 frames/sec or more. For displaying medical x-ray images on a CRT, we derived gray scale transform characteristics based on radiologists' comments during the experiment, and elucidated the relationship between that gray scale transform and the linearization transform for maintaining the linear relationship with the luminance of film on a light box (luminance linear transform). We then carried out viewing experiments based on a five-stage evaluation. Nine radiologists participated in our experiment, and the ten cases evaluated included pulmonary fibrosis, lung cancer, and pneumonia. The experimental results indicated that conventional film images and those on super high definition CRT monitors have nearly the same quality. They also show that the gray scale transform for CRT images decided according to radiologists' comments agrees with the luminance linear transform in the high luminance region. And in the low luminance region, it was found that the gray scale transform had the characteristics of level expansion to increase the number of levels that can be expressed.
HEKATE-A novel grazing incidence neutron scattering concept for the European Spallation Source.
Glavic, Artur; Stahn, Jochen
2018-03-01
Structure and magnetism at surfaces and buried interfaces on the nanoscale can only be accessed by few techniques, one of which is grazing incidence neutron scattering. While the technique has its strongest limitation in a low signal and large background, due to the low scattering probability and need for high resolution, it can be expected that the high intensity of the European Spallation Source in Lund, Sweden, will make many more such studies possible, warranting a dedicated beamline for this technique. We present an instrument concept, Highly Extended K range And Tunable Experiment (HEKATE), for surface scattering that combines the advantages of two Selene neutron guides with unique capabilities of spatially separated distinct wavelength frames. With this combination, it is not only possible to measure large specular reflectometry ranges, even on free liquid surfaces, but also to use two independent incident beams with tunable sizes and resolutions that can be optimized for the specifics of the investigated samples. Further the instrument guide geometry is tuned for reduction of high energy particle background and only uses low to moderate supermirror coatings for high reliability and affordable cost.
HEKATE—A novel grazing incidence neutron scattering concept for the European Spallation Source
NASA Astrophysics Data System (ADS)
Glavic, Artur; Stahn, Jochen
2018-03-01
Structure and magnetism at surfaces and buried interfaces on the nanoscale can only be accessed by few techniques, one of which is grazing incidence neutron scattering. While the technique has its strongest limitation in a low signal and large background, due to the low scattering probability and need for high resolution, it can be expected that the high intensity of the European Spallation Source in Lund, Sweden, will make many more such studies possible, warranting a dedicated beamline for this technique. We present an instrument concept, Highly Extended K range And Tunable Experiment (HEKATE), for surface scattering that combines the advantages of two Selene neutron guides with unique capabilities of spatially separated distinct wavelength frames. With this combination, it is not only possible to measure large specular reflectometry ranges, even on free liquid surfaces, but also to use two independent incident beams with tunable sizes and resolutions that can be optimized for the specifics of the investigated samples. Further the instrument guide geometry is tuned for reduction of high energy particle background and only uses low to moderate supermirror coatings for high reliability and affordable cost.
Advances and Challenges in Super-Resolution
2004-03-15
resolution in video. In: Proc. European Conf on Computer Vision (ECCV), May 2002, pp. 331–336. N. Sochen, R . Kimmel, R . Malladi . 1998. A general...2004a). 48 Vol. 14, 47–57 (2004) distinguish between a generic down-sampling operation (or CCD decimation by a factor r ) and the sampling...factor r often depends on the number of available low-resolution frames, the computational limitations (exponential in r ), and the accuracy of motion
High-speed Fourier ptychographic microscopy based on programmable annular illuminations.
Sun, Jiasong; Zuo, Chao; Zhang, Jialin; Fan, Yao; Chen, Qian
2018-05-16
High-throughput quantitative phase imaging (QPI) is essential to cellular phenotypes characterization as it allows high-content cell analysis and avoids adverse effects of staining reagents on cellular viability and cell signaling. Among different approaches, Fourier ptychographic microscopy (FPM) is probably the most promising technique to realize high-throughput QPI by synthesizing a wide-field, high-resolution complex image from multiple angle-variably illuminated, low-resolution images. However, the large dataset requirement in conventional FPM significantly limits its imaging speed, resulting in low temporal throughput. Moreover, the underlying theoretical mechanism as well as optimum illumination scheme for high-accuracy phase imaging in FPM remains unclear. Herein, we report a high-speed FPM technique based on programmable annular illuminations (AIFPM). The optical-transfer-function (OTF) analysis of FPM reveals that the low-frequency phase information can only be correctly recovered if the LEDs are precisely located at the edge of the objective numerical aperture (NA) in the frequency space. By using only 4 low-resolution images corresponding to 4 tilted illuminations matching a 10×, 0.4 NA objective, we present the high-speed imaging results of in vitro Hela cells mitosis and apoptosis at a frame rate of 25 Hz with a full-pitch resolution of 655 nm at a wavelength of 525 nm (effective NA = 0.8) across a wide field-of-view (FOV) of 1.77 mm 2 , corresponding to a space-bandwidth-time product of 411 megapixels per second. Our work reveals an important capability of FPM towards high-speed high-throughput imaging of in vitro live cells, achieving video-rate QPI performance across a wide range of scales, both spatial and temporal.
Ray Casting of Large Multi-Resolution Volume Datasets
NASA Astrophysics Data System (ADS)
Lux, C.; Fröhlich, B.
2009-04-01
High quality volume visualization through ray casting on graphics processing units (GPU) has become an important approach for many application domains. We present a GPU-based, multi-resolution ray casting technique for the interactive visualization of massive volume data sets commonly found in the oil and gas industry. Large volume data sets are represented as a multi-resolution hierarchy based on an octree data structure. The original volume data is decomposed into small bricks of a fixed size acting as the leaf nodes of the octree. These nodes are the highest resolution of the volume. Coarser resolutions are represented through inner nodes of the hierarchy which are generated by down sampling eight neighboring nodes on a finer level. Due to limited memory resources of current desktop workstations and graphics hardware only a limited working set of bricks can be locally maintained for a frame to be displayed. This working set is chosen to represent the whole volume at different local resolution levels depending on the current viewer position, transfer function and distinct areas of interest. During runtime the working set of bricks is maintained in CPU- and GPU memory and is adaptively updated by asynchronously fetching data from external sources like hard drives or a network. The CPU memory hereby acts as a secondary level cache for these sources from which the GPU representation is updated. Our volume ray casting algorithm is based on a 3D texture-atlas in GPU memory. This texture-atlas contains the complete working set of bricks of the current multi-resolution representation of the volume. This enables the volume ray casting algorithm to access the whole working set of bricks through only a single 3D texture. For traversing rays through the volume, information about the locations and resolution levels of visited bricks are required for correct compositing computations. We encode this information into a small 3D index texture which represents the current octree subdivision on its finest level and spatially organizes the bricked data. This approach allows us to render a bricked multi-resolution volume data set utilizing only a single rendering pass with no loss of compositing precision. In contrast most state-of-the art volume rendering systems handle the bricked data as individual 3D textures, which are rendered one at a time while the results are composited into a lower precision frame buffer. Furthermore, our method enables us to integrate advanced volume rendering techniques like empty-space skipping, adaptive sampling and preintegrated transfer functions in a very straightforward manner with virtually no extra costs. Our interactive volume ray tracing implementation allows high quality visualizations of massive volume data sets of tens of Gigabytes in size on standard desktop workstations.
Otsu, Yo; Bormuth, Volker; Wong, Jerome; Mathieu, Benjamin; Dugué, Guillaume P; Feltz, Anne; Dieudonné, Stéphane
2008-08-30
Two-photon microscopy offers the promise of monitoring brain activity at multiple locations within intact tissue. However, serial sampling of voxels has been difficult to reconcile with millisecond timescales characteristic of neuronal activity. This is due to the conflicting constraints of scanning speed and signal amplitude. The recent use of acousto-optic deflector scanning to implement random-access multiphoton microscopy (RAMP) potentially allows to preserve long illumination dwell times while sampling multiple points-of-interest at high rates. However, the real-life abilities of RAMP microscopy regarding sensitivity and phototoxicity issues, which have so far impeded prolonged optical recordings at high frame rates, have not been assessed. Here, we describe the design, implementation and characterisation of an optimised RAMP microscope. We demonstrate the application of the microscope by monitoring calcium transients in Purkinje cells and cortical pyramidal cell dendrites and spines. We quantify the illumination constraints imposed by phototoxicity and show that stable continuous high-rate recordings can be obtained. During these recordings the fluorescence signal is large enough to detect spikes with a temporal resolution limited only by the calcium dye dynamics, improving upon previous techniques by at least an order of magnitude.
Hadjisolomou, Stavros P; El-Haddad, George
2017-01-01
Coleoid cephalopods (squid, octopus, and sepia) are renowned for their elaborate body patterning capabilities, which are employed for camouflage or communication. The specific chromatic appearance of a cephalopod, at any given moment, is a direct result of the combined action of their intradermal pigmented chromatophore organs and reflecting cells. Therefore, a lot can be learned about the cephalopod coloration system by video recording and analyzing the activation of individual chromatophores in time. The fact that adult cephalopods have small chromatophores, up to several hundred thousand in number, makes measurement and analysis over several seconds a difficult task. However, current advancements in videography enable high-resolution and high framerate recording, which can be used to record chromatophore activity in more detail and accuracy in both space and time domains. In turn, the additional pixel information and extra frames per video from such recordings result in large video files of several gigabytes, even when the recording spans only few minutes. We created a software plugin, "SpotMetrics," that can automatically analyze high resolution, high framerate video of chromatophore organ activation in time. This image analysis software can track hundreds of individual chromatophores over several hundred frames to provide measurements of size and color. This software may also be used to measure differences in chromatophore activation during different behaviors which will contribute to our understanding of the cephalopod sensorimotor integration system. In addition, this software can potentially be utilized to detect numbers of round objects and size changes in time, such as eye pupil size or number of bacteria in a sample. Thus, we are making this software plugin freely available as open-source because we believe it will be of benefit to other colleagues both in the cephalopod biology field and also within other disciplines.
NASA Astrophysics Data System (ADS)
An, Lin; Shen, Tueng T.; Wang, Ruikang K.
2011-10-01
This paper presents comprehensive and depth-resolved retinal microvasculature images within human retina achieved by a newly developed ultrahigh sensitive optical microangiography (UHS-OMAG) system. Due to its high flow sensitivity, UHS-OMAG is much more sensitive to tissue motion due to the involuntary movement of the human eye and head compared to the traditional OMAG system. To mitigate these motion artifacts on final imaging results, we propose a new phase compensation algorithm in which the traditional phase-compensation algorithm is repeatedly used to efficiently minimize the motion artifacts. Comparatively, this new algorithm demonstrates at least 8 to 25 times higher motion tolerability, critical for the UHS-OMAG system to achieve retinal microvasculature images with high quality. Furthermore, the new UHS-OMAG system employs a high speed line scan CMOS camera (240 kHz A-line scan rate) to capture 500 A-lines for one B-frame at a 400 Hz frame rate. With this system, we performed a series of in vivo experiments to visualize the retinal microvasculature in humans. Two featured imaging protocols are utilized. The first is of the low lateral resolution (16 μm) and a wide field of view (4 × 3 mm2 with single scan and 7 × 8 mm2 for multiple scans), while the second is of the high lateral resolution (5 μm) and a narrow field of view (1.5 × 1.2 mm2 with single scan). The great imaging performance delivered by our system suggests that UHS-OMAG can be a promising noninvasive alternative to the current clinical retinal microvasculature imaging techniques for the diagnosis of eye diseases with significant vascular involvement, such as diabetic retinopathy and age-related macular degeneration.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ince-Cushman, A.; Rice, J. E.; Reinke, M. L.
2008-10-15
The use of high resolution x-ray crystal spectrometers to diagnose fusion plasmas has been limited by the poor spatial localization associated with chord integrated measurements. Taking advantage of a new x-ray imaging spectrometer concept [M. Bitter et al., Rev. Sci. Instrum. 75, 3660 (2004)], and improvements in x-ray detector technology [Ch. Broennimann et al., J. Synchrotron Radiat. 13, 120 (2006)], a spatially resolving high resolution x-ray spectrometer has been built and installed on the Alcator C-Mod tokamak. This instrument utilizes a spherically bent quartz crystal and a set of two dimensional x-ray detectors arranged in the Johann configuration [H. H.more » Johann, Z. Phys. 69, 185 (1931)] to image the entire plasma cross section with a spatial resolution of about 1 cm. The spectrometer was designed to measure line emission from H-like and He-like argon in the wavelength range 3.7 and 4.0 A with a resolving power of approximately 10 000 at frame rates up to 200 Hz. Using spectral tomographic techniques [I. Condrea, Phys. Plasmas 11, 2427 (2004)] the line integrated spectra can be inverted to infer profiles of impurity emissivity, velocity, and temperature. From these quantities it is then possible to calculate impurity density and electron temperature profiles. An overview of the instrument, analysis techniques, and example profiles are presented.« less
Prieto, Claudia; Uribe, Sergio; Razavi, Reza; Atkinson, David; Schaeffter, Tobias
2010-08-01
One of the current limitations of dynamic contrast-enhanced MR angiography is the requirement of both high spatial and high temporal resolution. Several undersampling techniques have been proposed to overcome this problem. However, in most of these methods the tradeoff between spatial and temporal resolution is constant for all the time frames and needs to be specified prior to data collection. This is not optimal for dynamic contrast-enhanced MR angiography where the dynamics of the process are difficult to predict and the image quality requirements are changing during the bolus passage. Here, we propose a new highly undersampled approach that allows the retrospective adaptation of the spatial and temporal resolution. The method combines a three-dimensional radial phase encoding trajectory with the golden angle profile order and non-Cartesian Sensitivity Encoding (SENSE) reconstruction. Different regularization images, obtained from the same acquired data, are used to stabilize the non-Cartesian SENSE reconstruction for the different phases of the bolus passage. The feasibility of the proposed method was demonstrated on a numerical phantom and in three-dimensional intracranial dynamic contrast-enhanced MR angiography of healthy volunteers. The acquired data were reconstructed retrospectively with temporal resolutions from 1.2 sec to 8.1 sec, providing a good depiction of small vessels, as well as distinction of different temporal phases.
Assessing resolution in live cell structured illumination microscopy
NASA Astrophysics Data System (ADS)
Pospíšil, Jakub; Fliegel, Karel; Klíma, Miloš
2017-12-01
Structured Illumination Microscopy (SIM) is a powerful super-resolution technique, which is able to enhance the resolution of optical microscope beyond the Abbe diffraction limit. In the last decade, numerous SIM methods that achieve the resolution of 100 nm in the lateral dimension have been developed. The SIM setups with new high-speed cameras and illumination pattern generators allow rapid acquisition of the live specimen. Therefore, SIM is widely used for investigation of the live structures in molecular and live cell biology. Quantitative evaluation of resolution enhancement in a real sample is essential to describe the efficiency of super-resolution microscopy technique. However, measuring the resolution of a live cell sample is a challenging task. Based on our experimental findings, the widely used Fourier ring correlation (FRC) method does not seem to be well suited for measuring the resolution of SIM live cell video sequences. Therefore, the resolution assessing methods based on Fourier spectrum analysis are often used. We introduce a measure based on circular average power spectral density (PSDca) estimated from a single SIM image (one video frame). PSDca describes the distribution of the power of a signal with respect to its spatial frequency. Spatial resolution corresponds to the cut-off frequency in Fourier space. In order to estimate the cut-off frequency from a noisy signal, we use a spectral subtraction method for noise suppression. In the future, this resolution assessment approach might prove useful also for single-molecule localization microscopy (SMLM) live cell imaging.
Multiplane wave imaging increases signal-to-noise ratio in ultrafast ultrasound imaging.
Tiran, Elodie; Deffieux, Thomas; Correia, Mafalda; Maresca, David; Osmanski, Bruno-Felix; Sieu, Lim-Anna; Bergel, Antoine; Cohen, Ivan; Pernot, Mathieu; Tanter, Mickael
2015-11-07
Ultrafast imaging using plane or diverging waves has recently enabled new ultrasound imaging modes with improved sensitivity and very high frame rates. Some of these new imaging modalities include shear wave elastography, ultrafast Doppler, ultrafast contrast-enhanced imaging and functional ultrasound imaging. Even though ultrafast imaging already encounters clinical success, increasing even more its penetration depth and signal-to-noise ratio for dedicated applications would be valuable. Ultrafast imaging relies on the coherent compounding of backscattered echoes resulting from successive tilted plane waves emissions; this produces high-resolution ultrasound images with a trade-off between final frame rate, contrast and resolution. In this work, we introduce multiplane wave imaging, a new method that strongly improves ultrafast images signal-to-noise ratio by virtually increasing the emission signal amplitude without compromising the frame rate. This method relies on the successive transmissions of multiple plane waves with differently coded amplitudes and emission angles in a single transmit event. Data from each single plane wave of increased amplitude can then be obtained, by recombining the received data of successive events with the proper coefficients. The benefits of multiplane wave for B-mode, shear wave elastography and ultrafast Doppler imaging are experimentally demonstrated. Multiplane wave with 4 plane waves emissions yields a 5.8 ± 0.5 dB increase in signal-to-noise ratio and approximately 10 mm in penetration in a calibrated ultrasound phantom (0.7 d MHz(-1) cm(-1)). In shear wave elastography, the same multiplane wave configuration yields a 2.07 ± 0.05 fold reduction of the particle velocity standard deviation and a two-fold reduction of the shear wave velocity maps standard deviation. In functional ultrasound imaging, the mapping of cerebral blood volume results in a 3 to 6 dB increase of the contrast-to-noise ratio in deep structures of the rodent brain.
Solomon Islands 2007 Tsunami Near-Field Modeling and Source Earthquake Deformation
NASA Astrophysics Data System (ADS)
Uslu, B.; Wei, Y.; Fritz, H.; Titov, V.; Chamberlin, C.
2008-12-01
The earthquake of 1 April 2007 left behind momentous footages of crust rupture and tsunami impact along the coastline of Solomon Islands (Fritz and Kalligeris, 2008; Taylor et al., 2008; McAdoo et al., 2008; PARI, 2008), while the undisturbed tsunami signals were also recorded at nearby deep-ocean tsunameters and coastal tide stations. These multi-dimensional measurements provide valuable datasets to tackle the challenging aspects at the tsunami source directly by inversion from tsunameter records in real time (available in a time frame of minutes), and its relationship with the seismic source derived either from the seismometer records (available in a time frame of hours or days) or from the crust rupture measurements (available in a time frame of months or years). The tsunami measurements in the near field, including the complex vertical crust motion and tsunami runup, are particularly critical to help interpreting the tsunami source. This study develops high-resolution inundation models for the Solomon Islands to compute the near-field tsunami impact. Using these models, this research compares the tsunameter-derived tsunami source with the seismic-derived earthquake sources from comprehensive perceptions, including vertical uplift and subsidence, tsunami runup heights and their distributional pattern among the islands, deep-ocean tsunameter measurements, and near- and far-field tide gauge records. The present study stresses the significance of the tsunami magnitude, source location, bathymetry and topography in accurately modeling the generation, propagation and inundation of the tsunami waves. This study highlights the accuracy and efficiency of the tsunameter-derived tsunami source in modeling the near-field tsunami impact. As the high- resolution models developed in this study will become part of NOAA's tsunami forecast system, these results also suggest expanding the system for potential applications in tsunami hazard assessment, search and rescue operations, as well as event and post-event planning in the Solomon Islands.
NASA Technical Reports Server (NTRS)
Rider, D.; Blavier, J-F.; Cunningham, T.; Hancock, B.; Key, R.; Pannell, Z.; Sander, S.; Seshadri, S.; Sun, C.; Wrigley, C.
2011-01-01
Focal plane arrays (FPAs) with high frame rates and many pixels benefit several upcoming Earth science missions including GEO-CAPE, GACM, and ACE by enabling broader spatial coverage and higher spectral resolution. FPAs for the PanFTS, a high spatial resolution Fourier transform spectrometer and a candidate instrument for the GEO-CAPE mission are the focus of the developments reported here, but this FPA technology has the potential to enable a variety of future measurements and instruments. The ESTO ACT Program funded the developed of a fast readout integrated circuit (ROIC) based on an innovative in-pixel analog-to-digital converter (ADC). The 128 X 128 pixel ROIC features 60 ?m pixels, a 14-bit ADC in each pixel and operates at a continuous frame rate of 14 kHz consuming only 1.1 W of power. The ROIC outputs digitized data completely eliminating the bulky, power consuming signal chains needed by conventional FPAs. The 128 X 128 pixel ROIC has been fabricated in CMOS and tested at the Jet Propulsion Laboratory. The current version is designed to be hybridized with PIN photodiode arrays via indium bump bonding for light detection in the visible and ultraviolet spectral regions. However, the ROIC design incorporates a small photodiode in each cell to permit detailed characterization of the ROICperformance without the need for hybridization. We will describe the essential features of the ROIC design and present results of ROIC performance measurements.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bzdek, Bryan R.; Reid, Jonathan P., E-mail: j.p.reid@bristol.ac.uk; Collard, Liam
We report studies of the coalescence of pairs of picolitre aerosol droplets manipulated with holographic optical tweezers, probing the shape relaxation dynamics following coalescence by simultaneously monitoring the intensity of elastic backscattered light (EBL) from the trapping laser beam (time resolution on the order of 100 ns) while recording high frame rate camera images (time resolution <10 μs). The goals of this work are to: resolve the dynamics of droplet coalescence in holographic optical traps; assign the origin of key features in the time-dependent EBL intensity; and validate the use of the EBL alone to precisely determine droplet surface tensionmore » and viscosity. For low viscosity droplets, two sequential processes are evident: binary coalescence first results from the overlap of the optical traps on the time scale of microseconds followed by the recapture of the composite droplet in an optical trap on the time scale of milliseconds. As droplet viscosity increases, the relaxation in droplet shape eventually occurs on the same time scale as recapture, resulting in a convoluted evolution of the EBL intensity that inhibits quantitative determination of the relaxation time scale. Droplet coalescence was simulated using a computational framework to validate both experimental approaches. The results indicate that time-dependent monitoring of droplet shape from the EBL intensity allows for robust determination of properties such as surface tension and viscosity. Finally, the potential of high frame rate imaging to examine the coalescence of dissimilar viscosity droplets is discussed.« less
Starr, Vanessa; Olivecrona, H; Noz, M E; Maguire, G Q; Zeleznik, M P; Jannsson, Karl-åke
2009-01-01
In this study we explore the possibility of accurately and cost-effectively monitoring tibial deformation induced by Taylor Spatial Frames (TSFs), using time-separated computed tomography (CT) scans and a volume fusion technique to determine tibial rotation and translation. Serial CT examinations (designated CT-A and CT-B, separated by a time interval of several months) of two patients were investigated using a previously described and validated volume fusion technique, in which user-defined landmarks drive the 3D registration of the two CT volumes. Both patients had undergone dual osteotomies to correct for tibial length and rotational deformity. For each registration, 10 or more landmarks were selected, and the quality of the fused volume was assessed both quantitatively and via 2D and 3D visualization tools. First, the proximal frame segment and tibia in CT-A and CT-B were brought into alignment (registered) by selecting landmarks on the frame and/or tibia. In the resulting "fused" volume, the proximal frame segment and tibia from CT-A and CT-B were aligned, while the distal frame segment and tibia from CT-A and CT-B were likely not aligned as a result of tibial deformation or frame adjustment having occurred between the CT scans. Using the proximal fused volume, the distal frame segment and tibia were then registered by selecting landmarks on the frame and/or tibia. The difference between the centroids of the final distal landmarks was used to evaluate the lengthening of the tibia, and the Euler angles from the registration were used to evaluate the rotation. Both the frame and bone could be effectively registered (based on visual interpretation). Movement between the proximal frame and proximal bone could be visualized in both cases. The spatial effect on the tibia could be both visually assessed and measured: 34 mm, 10 degrees in one case; 5 mm, 1 degrees in the other. This retrospective analysis of spatial correction of the tibia using Taylor Spatial Frames shows that CT offers an interesting potential means of quantitatively monitoring the patient's treatment. Compared with traditional techniques, modern CT scans in conjunction with image processing provide a high-resolution, spatially correct, and three-dimensional measurement system which can be used to quickly and easily assess the patient's treatment at low cost to the patient and hospital.
NASA Astrophysics Data System (ADS)
Isola, Ilaria; Fornaciai, Alessandro; Favalli, Massimiliano; Gigli, Giovanni; Nannipieri, Luca; Mucchi, Lorenzo; Intrieri, Emanuele; Pizziolo, Marco; Bertolini, Giovanni; Trippi, Federico; Casagli, Nicola; Schina, Rosa; Carnevale, Ennio
2017-04-01
High-resolution topographic data has been collected over the Lavina di Roncovetro active landslide (Reggio Emilia, Italy) for about 3 years by using various methods and technologies. Tha Lavina di Roncovetro landslide can be considered as a fluid-viscous mudflow, which can reach a down flow maximum rate of 10 m/day. The landslide started between the middle and the end of the XIX century and since then it has had a rapid evolution mainly characterized by the rapid retrogression of the crown to the extent that now reaches the top of Mount Staffola. In the frame of EU Wireless Sensor Network for Ground Instability Monitoring - Wi-GIM project (LIFE12ENV/IT/001033) the Lavina di Roncovetro landslide has been periodically tracked using technologies that span from the LiDAR, both terrestrial and aerial, to the Structure from Motion (SfM) photogrammetry method based on Unmanned Aerial Vehicle (UAV) and aerial survey. These data are used to create six high-resolution Digital Terrain Models (DEMs), which imaged the landslide surface on March 2014, October 2014, June 2015, July 2015, January 2016 and December 2016. Multi-temporal high-resolution topographic data have been used for qualitative and quantitative morphometric analysis and topographic change detection of the landslide with the aim to estimate and map the volume of removed and/or accumulated material, the average rates of vertical and horizontal displacement and the deformation structures affecting the landslide over the investigated period.
Laser-induced Microparticle Impact Experiments on Soft Materials
NASA Astrophysics Data System (ADS)
Kooi, Steven; Veysset, David; Maznev, Alexei; Yang, Yun Jung; Olsen, Bradley; Nelson, Keith
High-velocity impact testing is used to study fundamental aspects of materials behavior under high strain rates as well as in applications ranging from armor testing to the development of novel drug delivery platforms. In this work, we study high-velocity impact of micron-size projectiles on soft viscoelastic materials including synthetic hydrogels and gelatin samples. In an all optical laser-induced projectile impact test (LIPIT), a monolayer of microparticles is placed on a transparent substrate coated with a laser absorbing polymer layer. Ablation of a laser-irradiated polymer region accelerates the microparticles which are ejected from the launching pad into free space, reaching controllable speeds up to 1.5 km/s depending on the laser pulse energy and particle characteristics. The particles are monitored while in free space and after impact on the target surface with an ultrahigh-speed multi-frame camera that can record up to 16 images with time resolution of each frame as short as 3 ns. We present images and movies capturing individual particle impact and penetration in gels, and discuss the observed dynamics in the case of high Reynolds and Weber numbers. The results can provide direct input for modeling of high-velocity impact responses and high strain rate deformation in gels and other soft materials..
Samant, Sanjiv S; Gopal, Arun
2006-08-01
Image quality in portal imaging suffers significantly from the loss in contrast and spatial resolution that results from the excessive Compton scatter associated with megavoltage x rays. In addition, portal image quality is further reduced due to the poor quantum efficiency (QE) of current electronic portal imaging devices (EPIDs). Commercial video-camera-based EPIDs or VEPIDs that utilize a thin phosphor screen in conjunction with a metal buildup plate to convert the incident x rays to light suffer from reduced light production due to low QE (<2% for Eastman Kodak Lanex Fast-B). Flat-panel EPIDs that utilize the same luminescent screen along with an a-Si:H photodiode array provide improved image quality compared to VEPIDs, but they are expensive and can be susceptible to radiation damage to the peripheral electronics. In this article, we present a prototype VEPID system for high quality portal imaging at sub-monitor-unit (subMU) exposures based on a thick scintillation crystal (TSC) that acts as a high QE luminescent screen. The prototype TSC system utilizes a 12 mm thick transparent CsI(Tl) (thallium-activated cesium iodide) scintillator for QE=0.24, resulting in significantly higher light production compared to commercial phosphor screens. The 25 X 25 cm2 CsI(Tl) screen is coupled to a high spatial and contrast resolution Video-Optics plumbicon-tube camera system (1240 X 1024 pixels, 250 microm pixel width at isocenter, 12-bit ADC). As a proof-of-principle prototype, the TSC system with user-controlled camera target integration was adapted for use in an existing clinical gantry (Siemens BEAMVIEW(PLUS)) with the capability for online intratreatment fluoroscopy. Measurements of modulation transfer function (MTF) were conducted to characterize the TSC spatial resolution. The measured MTF along with measurements of the TSC noise power spectrum (NPS) were used to determine the system detective quantum efficiency (DQE). A theoretical expression of DQE(0) was developed to be used as a predictive model to propose improvements in the optics associated with the light detection. The prototype TSC provides DQE(0)=0.02 with its current imaging geometry, which is an order of magnitude greater than that for commercial VEPID systems and comparable to flat-panel imaging systems. Following optimization in the imaging geometry and the use of a high-end, cooled charge-coupled-device (CCD) camera system, the performance of the TSC is expected to improve even further. Based on our theoretical model, the expected DQE(0)=0.12 for the TSC system with the proposed improvements, which exceeds the performance of current flat-panel EPIDs. The prototype TSC provides high quality imaging even at subMU exposures (typical imaging dose is 0.2 MU per image), which offers the potential for daily patient localization imaging without increasing the weekly dose to the patient. Currently, the TSC is capable of limited frame-rate fluoroscopy for intratreatment visualization of patient motion at approximately 3 frames/second, since the achievable frame rate is significantly reduced by the limitations of the camera-control processor. With optimized processor control, the TSC is expected to be capable of intratreatment imaging exceeding 10 frames/second to monitor patient motion.
In vivo fluorescence imaging of primate retinal ganglion cells and retinal pigment epithelial cells
NASA Astrophysics Data System (ADS)
Gray, Daniel C.; Merigan, William; Wolfing, Jessica I.; Gee, Bernard P.; Porter, Jason; Dubra, Alfredo; Twietmeyer, Ted H.; Ahamd, Kamran; Tumbar, Remy; Reinholz, Fred; Williams, David R.
2006-08-01
The ability to resolve single cells noninvasively in the living retina has important applications for the study of normal retina, diseased retina, and the efficacy of therapies for retinal disease. We describe a new instrument for high-resolution, in vivo imaging of the mammalian retina that combines the benefits of confocal detection, adaptive optics, multispectral, and fluorescence imaging. The instrument is capable of imaging single ganglion cells and their axons through retrograde transport in ganglion cells of fluorescent dyes injected into the monkey lateral geniculate nucleus (LGN). In addition, we demonstrate a method involving simultaneous imaging in two spectral bands that allows the integration of very weak signals across many frames despite inter-frame movement of the eye. With this method, we are also able to resolve the smallest retinal capillaries in fluorescein angiography and the mosaic of retinal pigment epithelium (RPE) cells with lipofuscin autofluorescence.
Fast optically sectioned fluorescence HiLo endomicroscopy.
Ford, Tim N; Lim, Daryl; Mertz, Jerome
2012-02-01
We describe a nonscanning, fiber bundle endomicroscope that performs optically sectioned fluorescence imaging with fast frame rates and real-time processing. Our sectioning technique is based on HiLo imaging, wherein two widefield images are acquired under uniform and structured illumination and numerically processed to reject out-of-focus background. This work is an improvement upon an earlier demonstration of widefield optical sectioning through a flexible fiber bundle. The improved device features lateral and axial resolutions of 2.6 and 17 μm, respectively, a net frame rate of 9.5 Hz obtained by real-time image processing with a graphics processing unit (GPU) and significantly reduced motion artifacts obtained by the use of a double-shutter camera. We demonstrate the performance of our system with optically sectioned images and videos of a fluorescently labeled chorioallantoic membrane (CAM) in the developing G. gallus embryo. HiLo endomicroscopy is a candidate technique for low-cost, high-speed clinical optical biopsies.