2010 Military Family Life Project (MFLP): Tabulations of Response
2011-02-28
the leadership of Timothy Elig, Director, Human Resources Strategic Assessment Program (HRSAP). Policy officials contributing to the development of...of Kristin Williams, Branch Chief, is responsible for the development of questionnaires used in the survey program. Laverne Wright, Chief of Survey...DMDC’s Personnel Survey Branch, under the guidance of Branch Chief, David McGrath, is responsible for developing the sampling and weighting methods
Sugiura, D; Tateno, M
2013-08-01
We investigated the nitrogen and carbohydrate allocation patterns of trees under heterogeneous light environments using saplings of the devil maple tree (Acer diabolicum) with Y-shaped branches. Different branch groups were created: all branches of a sapling exposed to full light (L-branches), all branches exposed to full shade (S-branches), and half of the branches of a sapling exposed to light (HL-branches) and the other half exposed to shade (HS-branches). Throughout the growth period, nitrogen was preferentially allocated to HL-branches, whereas nitrogen allocation to HS-branches was suppressed compared to L- and S-branches. HL-branches with the highest leaf nitrogen content (N(area)) also had the highest rates of growth, and HS-branches with the lowest N(area) had the lowest observed growth rates. In addition, net nitrogen assimilation, estimated using a photosynthesis model, was strongly correlated with branch growth and whole-plant growth. In contrast, patterns of photosynthate allocation to branches and roots were not affected by the light conditions of the other branch. These observations suggest that tree canopies develop as a result of resource allocation patterns, where the growth of sun-lit branches is favoured over shaded branches, which leads to enhanced whole-plant growth in heterogeneous light environments. Our results indicate that whole-plant growth is enhanced by the resource allocation patterns created for saplings in heterogeneous light environments.
Social and Economic Analysis Branch: integrating policy, social, economic, and natural science
Schuster, Rudy; Walters, Katie D.
2015-01-01
The Fort Collins Science Center's Social and Economic Analysis Branch provides unique capabilities in the U.S. Geological Survey by leading projects that integrate social, behavioral, economic, and natural science in the context of human–natural resource interactions. Our research provides scientific understanding and support for the management and conservation of our natural resources in support of multiple agency missions. We focus on meeting the scientific needs of the Department of the Interior natural resource management bureaus in addition to fostering partnerships with other Federal and State managers to protect, restore, and enhance our environment. The Social and Economic Analysis Branch has an interdisciplinary group of scientists whose primary functions are to conduct both theoretical and applied social science research, provide technical assistance, and offer training to support the development of skills in natural resource management activities. Management and research issues associated with human-resource interactions typically occur in a unique context and require knowledge of both natural and social sciences, along with the skill to integrate multiple science disciplines. In response to these challenging contexts, Social and Economic Analysis Branch researchers apply a wide variety of social science concepts and methods which complement our rangeland/agricultural, wildlife, ecology, and biology capabilities. The goal of the Social and Economic Analysis Branch's research is to enhance natural-resource management, agency functions, policies, and decisionmaking.
Risk Factor Assessment Branch (RFAB)
The Risk Factor Assessment Branch (RFAB) focuses on the development, evaluation, and dissemination of high-quality risk factor metrics, methods, tools, technologies, and resources for use across the cancer research continuum, and the assessment of cancer-related risk factors in the population.
Navy Manpower Planning and Programming: Basis for Systems Examination
1974-10-01
IRE5EARCH AND DEVEl. INAVAL RESEARCH] CHIEF OF NAVAL OPERATIONS OFFICE CHIIf OF NAVAL OPERATIONS NAVAL MATERIAL COMMAND •LitMARTERS NAVAL MATERIAL...DIVISION COMPENSATION BRANCH MANPOWER PROGRAMMING ■RANCH JOURNAL/TRADE TALK BRANCH 06A ASSISTANT FOR COMPUTER SCIENCES SYSTEMS DEVELOPMENT BRANCH...Assistant Director, Life Sciences , Air Force Office of Scientific Research Technical Library, Air Force Human Resources Laboratory, Lackland Air Force Base
ERIC Educational Resources Information Center
Butcher, Jennifer; Kritsonis, William Allan
2007-01-01
Human Resource Management is a branch of an organization which recruits and develops personnel to promote the organization's objectives. Human Resource Management involves interviewing applicants, training staff, and employee retention. Compensation, benefits, employee/labor relations, health, safety, and security issues are a few of the aspects…
1980-10-01
a bakery , a gas station, and the Linden Street bridge were flooded during the March 1977 storm. Flooding also occurred on the Southwest Branch...and service station, one bakery , and five other commercial establishments. Most of these structures are not suited to being elevated above the design...of a shopping plaza and a fast-food franchise in the flood plain on West Housatonic Street (Route 20). The following three alternate plans of
Spatial mapping and quantification of developmental branching morphogenesis.
Short, Kieran; Hodson, Mark; Smyth, Ian
2013-01-15
Branching morphogenesis is a fundamental developmental mechanism that shapes the formation of many organs. The complex three-dimensional shapes derived by this process reflect equally complex genetic interactions between branching epithelia and their surrounding mesenchyme. Despite the importance of this process to normal adult organ function, analysis of branching has been stymied by the absence of a bespoke method to quantify accurately the complex spatial datasets that describe it. As a consequence, although many developmentally important genes are proposed to influence branching morphogenesis, we have no way of objectively assessing their individual contributions to this process. We report the development of a method for accurately quantifying many aspects of branching morphogenesis and we demonstrate its application to the study of organ development. As proof of principle we have employed this approach to analyse the developing mouse lung and kidney, describing the spatial characteristics of the branching ureteric bud and pulmonary epithelia. To demonstrate further its capacity to profile unrecognised genetic contributions to organ development, we examine Tgfb2 mutant kidneys, identifying elements of both developmental delay and specific spatial dysmorphology caused by haplo-insufficiency for this gene. This technical advance provides a crucial resource that will enable rigorous characterisation of the genetic and environmental factors that regulate this essential and evolutionarily conserved developmental mechanism.
The Evolution of Army Leader Development
2013-03-01
Human Resources Command, OPMD- MFE -I. 4 U.S. Army General Officer Management Office, Army General Officer Roster (Washington, DC, U.S. Department of the...Human Resources Command, Command Management Branch post board data analysis. 15 Data from the United States Army Human Resources Command, OPMD- MFE -A...May 1, 2008), D-1. 25 19 Data from the United States Army Human Resources Command, OPMD- MFE -A, 01 February, 2013. 20 U.S. Joint Chiefs of
NASA Astrophysics Data System (ADS)
Setegn, S. G.; Mahmoudi, M.; Lawrence, A.; Duque, N.
2015-12-01
The Applied Research Center at Florida International University (ARC-FIU) is supporting the soil and groundwater remediation efforts of the U.S. Department of Energy (DOE) Savannah River Site (SRS) by developing a surface water model to simulate the hydrology and the fate and transport of contaminants and sediment in the Tims Branch watershed. Hydrological models are useful tool in water and land resource development and decision-making for watershed management. Moreover, simulation of hydrological processes improves understanding of the environmental dynamics and helps to manage and protect water resources and the environment. MIKE SHE, an advanced integrated modeling system is used to simulate the hydrological processes of the Tim Branch watershed with the objective of developing an integrated modeling system to improve understanding of the physical, chemical and biological processes within the Tims Branch watershed. MIKE SHE simulates water flow in the entire land based phase of the hydrological cycle from rainfall to river flow, via various flow processes such as, overland flow, infiltration, evapotranspiration, and groundwater flow. In this study a MIKE SHE model is developed and applied to the Tim branch watershed to study the watershed response to storm events and understand the water balance of the watershed under different climatic and catchment characteristics. The preliminary result of the integrated model indicated that variation in the depth of overland flow highly depend on the amount and distribution of rainfall in the watershed. The ultimate goal of this project is to couple the MIKE SHE and MIKE 11 models to integrate the hydrological component in the land phase of hydrological cycle and stream flow process. The coupled MIKE SHE/MIKE 11 model will further be integrated with an Ecolab module to represent a range of water quality, contaminant transport, and ecological processes with respect to the stream, surface water and groundwater in the Tims Branch watershed at Savannah River Site.
Song, Wei; Qin, Shao-Tong; Fang, Fei-Xiang; Gao, Zhen-Jiang; Liang, Dan-Dan; Liu, Lu-Lu; Tian, Hong-Tao; Yang, Hai-Bo
2018-06-01
Prunus cerasifera has a rich resource and a weak utilization rate and its biological functions have been investigated. We found that the contents of total phenol (TP) in leaves and branches of Prunus cerasifera were 117.8 ± 8.8 and 100.04 ± 0.9 mg/g, respectively; the contents of soluble condensed tannin (SCT) were 73.95 ± 0.9 and 78.65 ± 4.1 mg/g, respectively; the structure of SCT containing afzelechin/epiafzelechin, catechin/epicatechin, and atechin/epicatechin as the main units and the SCT from leaves and branches exhibited better anti-tyrosinase and antioxidant activities. This study could clarify Prunus cerasifera condensed tannin resource availability and lay a theoretical foundation for its development as a natural antioxidant and tyrosinase inhibitor.
Aquatics Systems Branch: transdisciplinary research to address water-related environmental problems
Dong, Quan; Walters, Katie D.
2015-01-01
The Aquatic Systems Branch at the Fort Collins Science Center is a group of scientists dedicated to advancing interdisciplinary science and providing science support to solve water-related environmental issues. Natural resource managers have an increasing need for scientific information and stakeholders face enormous challenges of increasing and competing demands for water. Our scientists are leaders in ecological flows, riparian ecology, hydroscape ecology, ecosystem management, and contaminant biology. The Aquatic Systems Branch employs and develops state-of-the-science approaches in field investigations, laboratory experiments, remote sensing, simulation and predictive modeling, and decision support tools. We use the aquatic experimental laboratory, the greenhouse, the botanical garden and other advanced facilities to conduct unique research. Our scientists pursue research on the ground, in the rivers, and in the skies, generating and testing hypotheses and collecting quantitative information to support planning and design in natural resource management and aquatic restoration.
The San Pedro Data Browser was developed by the Landscape Ecology Branch of the U.S. Environmental Protection Agency (Las Vegas, NV). The goal of the Landscape Sciences Program is to improve decision-making relative to natural and human resource management through the development...
ERIC Educational Resources Information Center
Barker-Plummer, Bernadette
1995-01-01
Elaborates a conceptualization of news as a discursive resource, and suggests a dialogical model for media-movement relationships. Describes how two "branches" of the United States women's movement understood news differently and developed different and specific strategies which are called "media pragmatism" and "media subversion." (SR)
Duchateau, Emmanuel; Auty, David; Mothe, Frédéric; Longuetaud, Fleur; Ung, Chhun Huor
2015-01-01
The branch autonomy principle, which states that the growth of individual branches can be predicted from their morphology and position in the forest canopy irrespective of the characteristics of the tree, has been used to simplify models of branch growth in trees. However, observed changes in allocation priority within trees towards branches growing in light-favoured conditions, referred to as ‘Milton’s Law of resource availability and allocation,’ have raised questions about the applicability of the branch autonomy principle. We present models linking knot ontogeny to the secondary growth of the main stem in black spruce (Picea mariana (Mill.) B.S.P.), which were used to assess the patterns of assimilate allocation over time, both within and between trees. Data describing the annual radial growth of 445 stem rings and the three-dimensional shape of 5,377 knots were extracted from optical scans and X-ray computed tomography images taken along the stems of 10 trees. Total knot to stem area increment ratios (KSR) were calculated for each year of growth, and statistical models were developed to describe the annual development of knot diameter and curvature as a function of stem radial increment, total tree height, stem diameter, and the position of knots along an annual growth unit. KSR varied as a function of tree age and of the height to diameter ratio of the stem, a variable indicative of the competitive status of the tree. Simulations of the development of an individual knot showed that an increase in the stem radial growth rate was associated with an increase in the initial growth of the knot, but also with a shorter lifespan. Our results provide support for ‘Milton’s Law,’ since they indicate that allocation priority is given to locations where the potential return is the highest. The developed models provided realistic simulations of knot morphology within trees, which could be integrated into a functional-structural model of tree growth and above-ground resource partitioning. PMID:25870769
Duchateau, Emmanuel; Auty, David; Mothe, Frédéric; Longuetaud, Fleur; Ung, Chhun Huor; Achim, Alexis
2015-01-01
The branch autonomy principle, which states that the growth of individual branches can be predicted from their morphology and position in the forest canopy irrespective of the characteristics of the tree, has been used to simplify models of branch growth in trees. However, observed changes in allocation priority within trees towards branches growing in light-favoured conditions, referred to as 'Milton's Law of resource availability and allocation,' have raised questions about the applicability of the branch autonomy principle. We present models linking knot ontogeny to the secondary growth of the main stem in black spruce (Picea mariana (Mill.) B.S.P.), which were used to assess the patterns of assimilate allocation over time, both within and between trees. Data describing the annual radial growth of 445 stem rings and the three-dimensional shape of 5,377 knots were extracted from optical scans and X-ray computed tomography images taken along the stems of 10 trees. Total knot to stem area increment ratios (KSR) were calculated for each year of growth, and statistical models were developed to describe the annual development of knot diameter and curvature as a function of stem radial increment, total tree height, stem diameter, and the position of knots along an annual growth unit. KSR varied as a function of tree age and of the height to diameter ratio of the stem, a variable indicative of the competitive status of the tree. Simulations of the development of an individual knot showed that an increase in the stem radial growth rate was associated with an increase in the initial growth of the knot, but also with a shorter lifespan. Our results provide support for 'Milton's Law,' since they indicate that allocation priority is given to locations where the potential return is the highest. The developed models provided realistic simulations of knot morphology within trees, which could be integrated into a functional-structural model of tree growth and above-ground resource partitioning.
NASA Astrophysics Data System (ADS)
Skapare, I.; Kreslins, A.; Cers, A.
2016-09-01
Latvia currently is self-sufficient in energy resources up to approximately 35 %. Annual fossil energy prices rise and risks of security of energy supply promote the development legislation in the matter of renewable resources. One of the Latvian Ministry of Economics' recent products is a new draft law called the "Renewable Energy Law", which has been created due to one of the European Union and Latvian national energy policy objectives: to increase the share of renewable energy up to 40 % by 2020 (Moore and Vanags, 2012). Currently, geothermal energy potential is assessed at 1 × 1013 kWh; nevertheless, it is difficult for geothermal energy to compete with other renewable energy resources in the Latvian energy market. A great job has been done in recent years at the legislative branch to choose the right methods for supporting the use of renewable energy resources. This paper aims is analysis of current situation and assessment of Latvian legislation possibilities to promote the use of geothermal energy.
An Analysis of the President’s Budgetary Proposals for Fiscal Year 1991
1990-03-01
Operations Interior Labor, Health and Human Services, Education Legislative Branch Rural Development , Agriculture Transportation Treasury, Postal Service...and State (with jurisdiction over the census), Interior (responsible for many energy and natural resource programs), Rural Development and Agriculture... Development . Once again, the budget proposes to scale back funding for rural economic development programs and to eliminate the Economic Development
Negotiation Training Courses for Natural Resource Professionals
Burkardt, Nina; Swann, M. Earlene; Walters, Katherine
2006-01-01
FORT's Policy Analysis and Science Assistance Branch (PASA) has been conducting and publishing research on multi-party natural resource negotiation since the 1980s. This research has led to the development of basic and advanced negotiation training courses. Each course is two-and-a-half days. Both courses are a mix of lecture, hands-on training, and discussion. Please join us and other natural resource professionals facing similar problems and share your experiences. Come prepared to candidly discuss examples of successes to embrace, stalemates to recognize, and pitfalls to avoid in natural resource negotiations.
Mathematic model of regional economy development by the final result of labor resources
NASA Astrophysics Data System (ADS)
Zaitseva, Irina; Malafeev, Oleg; Strekopytov, Sergei; Bondarenko, Galina; Lovyannikov, Denis
2018-04-01
This article presents the mathematic model of regional economy development based on the result of labor resources. The solution of a region development-planning problem is considered for the period of long-lasting planning taking into account the beginning and the end of the planned period. The challenge is to find the distribution of investments in the main and additional branches of the regional economy, which will provide simultaneous transaction of all major sectors of the regional economy from the given condition to the predetermined final state.
30 CFR 56.6403 - Branch circuits.
Code of Federal Regulations, 2010 CFR
2010-07-01
... SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Explosives Electric Blasting § 56.6403 Branch circuits. (a) If electric blasting includes the use of branch circuits, each... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Branch circuits. 56.6403 Section 56.6403...
Near East/South Asia Report, No. 2746.
1983-04-29
cooperation among the many and varied branches of media in the Islamic states taken its intended meaning so that this utilization and cooperation is... utilization [of these resources] during 1980 and 1981. Chapter XI. Human Resources This chapter consists of a study and analysis of figures dealing with the...recurring expenditure amounts to 1.146 billion dollars and development ex- penditure 1.086 billion dollars. Among the specialized banks, the
Laboratory Branches Hydrologic Software Engineering Branch (HSEB) Hydrologic Science and Modeling Branch (HSMB) General Info Publications Documentation Software Standard and Guidelines Contact Us HL Staff resources and services. Staff Directory Chief, Hydrology Laboratory; Chief, Hydrologic Software Engineering
Branching habit and the allocation of reproductive resources in conifers.
Leslie, Andrew B
2012-09-01
Correlated relationships between branch thickness, branch density, and twig and leaf size have been used extensively to study the evolution of plant canopy architecture, but fewer studies have explored the impact of these relationships on the allocation of reproductive resources. This study quantifies pollen cone production in conifers, which have similar basic reproductive biology but vary dramatically in branching habit, in order to test how differences in branch diameter influence pollen cone size and the density with which they are deployed in the canopy. Measurements of canopy branch density, the number of cones per branch and cone size were used to estimate the amount of pollen cone tissues produced by 16 species in three major conifer clades. The number of pollen grains produced was also estimated using direct counts from individual pollen cones. The total amount of pollen cone tissues in the conifer canopy varied little among species and clades, although vegetative traits such as branch thickness, branch density and pollen cone size varied over several orders of magnitude. However, branching habit controls the way these tissues are deployed: taxa with small branches produce small pollen cones at a high density, while taxa with large branches produce large cones relatively sparsely. Conifers appear to invest similar amounts of energy in pollen production independent of branching habit. However, similar associations between branch thickness, branch density and pollen cone size are seen across conifers, including members of living and extinct groups not directly studied here. This suggests that reproductive features relating to pollen cone size are in large part a function of the evolution of vegetative morphology and branching habit.
Information Access Policy & Compliance Branch
Information Access Policy & Compliance Branch Join the Air Force Home Offices By Command By Base Library Handbook Annual Reports Resources Privacy Act Search Information Access Policy & Compliance Branch75 FR 2878 - National Cancer Institute; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-19
..., Resources and Training Review Branch, Division of Extramural Activities, National Cancer Institute, 6116... Officer, Research Programs Review Branch, Division of Extramural Activities, National Cancer Institute... Ahmad, PhD, Scientific Review Officer, Research Programs Review Branch, Division of Extramural...
Kamel Boulos, M N; Roudsari, A V; Gordon, C; Muir Gray, J A
2001-01-01
In 1998, the U.K. National Health Service Information for Health Strategy proposed the implementation of a National electronic Library for Health to provide clinicians, healthcare managers and planners, patients and the public with easy, round the clock access to high quality, up-to-date electronic information on health and healthcare. The Virtual Branch Libraries are among the most important components of the National electronic Library for Health. They aim at creating online knowledge based communities, each concerned with some specific clinical and other health-related topics. This study is about the envisaged Dermatology Virtual Branch Libraries of the National electronic Library for Health. It aims at selecting suitable dermatology Web resources for inclusion in the forthcoming Virtual Branch Libraries after establishing preliminary quality benchmarking rules for this task. Psoriasis, being a common dermatological condition, has been chosen as a starting point. Because quality is a principal concern of the National electronic Library for Health, the study includes a review of the major quality benchmarking systems available today for assessing health-related Web sites. The methodology of developing a quality benchmarking system has been also reviewed. Aided by metasearch Web tools, candidate resources were hand-selected in light of the reviewed benchmarking systems and specific criteria set by the authors. Over 90 professional and patient-oriented Web resources on psoriasis and dermatology in general are suggested for inclusion in the forthcoming Dermatology Virtual Branch Libraries. The idea of an all-in knowledge-hallmarking instrument for the National electronic Library for Health is also proposed based on the reviewed quality benchmarking systems. Skilled, methodical, organized human reviewing, selection and filtering based on well-defined quality appraisal criteria seems likely to be the key ingredient in the envisaged National electronic Library for Health service. Furthermore, by promoting the application of agreed quality guidelines and codes of ethics by all health information providers and not just within the National electronic Library for Health, the overall quality of the Web will improve with time and the Web will ultimately become a reliable and integral part of the care space.
ERIC Educational Resources Information Center
Pierce, Preston E., Comp.
A compilation of resources is provided for those interested in examining action taken by the executive branch of the federal government to foster scientific and engineering excellence in the United States in the nineteenth century. The resources are intended for use by pre-college secondary science and social studies teachers. Each of the…
Branching habit and the allocation of reproductive resources in conifers
Leslie, Andrew B.
2012-01-01
Background and Aims Correlated relationships between branch thickness, branch density, and twig and leaf size have been used extensively to study the evolution of plant canopy architecture, but fewer studies have explored the impact of these relationships on the allocation of reproductive resources. This study quantifies pollen cone production in conifers, which have similar basic reproductive biology but vary dramatically in branching habit, in order to test how differences in branch diameter influence pollen cone size and the density with which they are deployed in the canopy. Methods Measurements of canopy branch density, the number of cones per branch and cone size were used to estimate the amount of pollen cone tissues produced by 16 species in three major conifer clades. The number of pollen grains produced was also estimated using direct counts from individual pollen cones. Key Results The total amount of pollen cone tissues in the conifer canopy varied little among species and clades, although vegetative traits such as branch thickness, branch density and pollen cone size varied over several orders of magnitude. However, branching habit controls the way these tissues are deployed: taxa with small branches produce small pollen cones at a high density, while taxa with large branches produce large cones relatively sparsely. Conclusions Conifers appear to invest similar amounts of energy in pollen production independent of branching habit. However, similar associations between branch thickness, branch density and pollen cone size are seen across conifers, including members of living and extinct groups not directly studied here. This suggests that reproductive features relating to pollen cone size are in large part a function of the evolution of vegetative morphology and branching habit. PMID:22782240
30 CFR 57.6403 - Branch circuits.
Code of Federal Regulations, 2010 CFR
2010-07-01
... SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Explosives Electric Blasting-Surface and Underground § 57.6403 Branch circuits. (a) If electric blasting includes the use of... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Branch circuits. 57.6403 Section 57.6403...
Invasive Species Science Branch: research and management tools for controlling invasive species
Reed, Robert N.; Walters, Katie D.
2015-01-01
Invasive, nonnative species of plants, animals, and disease organisms adversely affect the ecosystems they enter. Like “biological wildfires,” they can quickly spread and affect nearly all terrestrial and aquatic ecosystems. Invasive species have become one of the greatest environmental challenges of the 21st century in economic, environmental, and human health costs, with an estimated effect in the United States of more than $120 billion per year. Managers of the Department of the Interior and other public and private lands often rank invasive species as their top resource management problem. The Invasive Species Science Branch of the Fort Collins Science Center provides research and technical assistance relating to management concerns for invasive species, including understanding how these species are introduced, identifying areas vulnerable to invasion, forecasting invasions, and developing control methods. To disseminate this information, branch scientists are developing platforms to share invasive species information with DOI cooperators, other agency partners, and the public. From these and other data, branch scientists are constructing models to understand and predict invasive species distributions for more effective management. The branch also has extensive herpetological and population biology expertise that is applied to harmful reptile invaders such as the Brown Treesnake on Guam and Burmese Python in Florida.
PyPWA: A partial-wave/amplitude analysis software framework
NASA Astrophysics Data System (ADS)
Salgado, Carlos
2016-05-01
The PyPWA project aims to develop a software framework for Partial Wave and Amplitude Analysis of data; providing the user with software tools to identify resonances from multi-particle final states in photoproduction. Most of the code is written in Python. The software is divided into two main branches: one general-shell where amplitude's parameters (or any parametric model) are to be estimated from the data. This branch also includes software to produce simulated data-sets using the fitted amplitudes. A second branch contains a specific realization of the isobar model (with room to include Deck-type and other isobar model extensions) to perform PWA with an interface into the computer resources at Jefferson Lab. We are currently implementing parallelism and vectorization using the Intel's Xeon Phi family of coprocessors.
METHODS FOR AQUATIC RESOURCE ASSESSMENT (MARA) FY 2008 - 2012
For the past 17 years, members of the Freshwater Ecology Branch (FEB) at EPA’s Western Ecology Division (WED) have been engaged in research to develop the concepts and tools that would allow EPA and it’s partners to monitor the status and trends in the condition of freshwater sys...
Flood of October 8, 1962, on Bachman Branch and Joes Creek at Dallas, Texas
Ruggles, Frederick H.
1966-01-01
This report presents hydrologic data that enable the user to define areas susceptible to flooding and to evaluate the flood hazard along Bachman Branch and Joes Creek. The data provide a technical basis for making sound decisions concerning the use of flood-plain lands. The report will be useful for preparing building and zoning regulations, locating waste disposal facilities, purchasing unoccupied land, developing recreational areas, and managing surface water in relation to ground-water resources. This is one of the series of reports delineating the flood hazard on streams in the Dallas area.
Attorney General Opinions Executive Branch Ethics Criminal Justice Alaska Medicaid Fraud Control Anchorage Abuse Executive Branch Ethics Law Resources Public Safety Action Plan Federal Issues and Conflicts - PDF
Educational Resources The Pediatric Oncology Branch has produced a number of educational and therapeutic materials to help the children we serve learn about their condition and cope with the challenges they might face as a result of their illness. If you are interested in any of these resources, contact Lori Wiener, Ph.D., at wienerl@mail.nih.gov.
Knowledge-based systems for power management
NASA Technical Reports Server (NTRS)
Lollar, L. F.
1992-01-01
NASA-Marshall's Electrical Power Branch has undertaken the development of expert systems in support of further advancements in electrical power system automation. Attention is given to the features (1) of the Fault Recovery and Management Expert System, (2) a resource scheduler or Master of Automated Expert Scheduling Through Resource Orchestration, and (3) an adaptive load-priority manager, or Load Priority List Management System. The characteristics of an advisory battery manager for the Hubble Space Telescope, designated the 'nickel-hydrogen expert system', are also noted.
Calderón-Cortés, Nancy; Uribe-Mú, Claudia A; Martínez-Méndez, A Karen; Escalera-Vázquez, Luis H; Cristobal-Pérez, E Jacob; García-Oliva, Felipe; Quesada, Mauricio
2016-01-01
Ecosystem engineering by insect herbivores occurs as the result of structural modification of plants manipulated by insects. However, only few studies have evaluated the effect of these modifications on the plant responses induced by stem-borers that act as ecosystem engineers. In this study, we evaluated the responses induced by the herbivory of the twig-girdler beetle Oncideres albomarginata chamela (Cerambycidae: Lamiinae) on its host plant Spondias purpurea (Anacardiaceae), and its relationship with the ecosystem engineering process carried out by this stem-borer. Our results demonstrated that O. albomarginata chamela branch removal induced the development of lateral branches increasing the resources needed for the development of future insect generations, of its own offspring and of many other insect species. Detached branches represent habitats with high content of nitrogen and phosphorous, which eventually can be incorporated into the ecosystem, increasing nutrient cycling efficiency. Consequently, branch removal and the subsequent plant tissue regeneration induced by O. albomarginata chamela represent key mechanisms underlying the ecosystem engineering process carried out by this stem-borer, which enhances arthropod diversity in the ecosystem. Copyright © 2015 Elsevier Ltd. All rights reserved.
Roudsari, AV; Gordon, C; Gray, JA Muir
2001-01-01
Background In 1998, the U.K. National Health Service Information for Health Strategy proposed the implementation of a National electronic Library for Health to provide clinicians, healthcare managers and planners, patients and the public with easy, round the clock access to high quality, up-to-date electronic information on health and healthcare. The Virtual Branch Libraries are among the most important components of the National electronic Library for Health . They aim at creating online knowledge based communities, each concerned with some specific clinical and other health-related topics. Objectives This study is about the envisaged Dermatology Virtual Branch Libraries of the National electronic Library for Health . It aims at selecting suitable dermatology Web resources for inclusion in the forthcoming Virtual Branch Libraries after establishing preliminary quality benchmarking rules for this task. Psoriasis, being a common dermatological condition, has been chosen as a starting point. Methods Because quality is a principal concern of the National electronic Library for Health, the study includes a review of the major quality benchmarking systems available today for assessing health-related Web sites. The methodology of developing a quality benchmarking system has been also reviewed. Aided by metasearch Web tools, candidate resources were hand-selected in light of the reviewed benchmarking systems and specific criteria set by the authors. Results Over 90 professional and patient-oriented Web resources on psoriasis and dermatology in general are suggested for inclusion in the forthcoming Dermatology Virtual Branch Libraries. The idea of an all-in knowledge-hallmarking instrument for the National electronic Library for Health is also proposed based on the reviewed quality benchmarking systems. Conclusions Skilled, methodical, organized human reviewing, selection and filtering based on well-defined quality appraisal criteria seems likely to be the key ingredient in the envisaged National electronic Library for Health service. Furthermore, by promoting the application of agreed quality guidelines and codes of ethics by all health information providers and not just within the National electronic Library for Health, the overall quality of the Web will improve with time and the Web will ultimately become a reliable and integral part of the care space. PMID:11720947
Postma, Johannes Auke; Dathe, Annette; Lynch, Jonathan Paul
2014-01-01
Observed phenotypic variation in the lateral root branching density (LRBD) in maize (Zea mays) is large (1–41 cm−1 major axis [i.e. brace, crown, seminal, and primary roots]), suggesting that LRBD has varying utility and tradeoffs in specific environments. Using the functional-structural plant model SimRoot, we simulated the three-dimensional development of maize root architectures with varying LRBD and quantified nitrate and phosphorus uptake, root competition, and whole-plant carbon balances in soils varying in the availability of these nutrients. Sparsely spaced (less than 7 branches cm−1), long laterals were optimal for nitrate acquisition, while densely spaced (more than 9 branches cm−1), short laterals were optimal for phosphorus acquisition. The nitrate results are mostly explained by the strong competition between lateral roots for nitrate, which causes increasing LRBD to decrease the uptake per unit root length, while the carbon budgets of the plant do not permit greater total root length (i.e. individual roots in the high-LRBD plants stay shorter). Competition and carbon limitations for growth play less of a role for phosphorus uptake, and consequently increasing LRBD results in greater root length and uptake. We conclude that the optimal LRBD depends on the relative availability of nitrate (a mobile soil resource) and phosphorus (an immobile soil resource) and is greater in environments with greater carbon fixation. The median LRBD reported in several field screens was 6 branches cm−1, suggesting that most genotypes have an LRBD that balances the acquisition of both nutrients. LRBD merits additional investigation as a potential breeding target for greater nutrient acquisition. PMID:24850860
NASA Astrophysics Data System (ADS)
González-Pelayo, Óscar; Llovet, Joan; Giménez-Morera, Antonio; Jordán, Antonio; Pereira, Paulo; Novara, Agata; García-Orenes, Fuensanta; Cerdà, Artemi
2015-04-01
Soil water erosion is causing problems on the agriculture land of the world. The high erosion rates registered in the agriculture land are due to the lack of a vegetation cover that protects the soil. High erosion rates in agriculture lands are found in Africa, Europe, Asia, and any other continent. Soil erosion on citrus orchards has been researched recently and shown huge erosion rates in the Mediterranean and in China. All this research findings allow us to confirm that the soil erosion rates on citrus orchards are not sustainable and strategies to control the soil erosion should be applied. The increasing erosion rates are due to the bare soils, but also are due to the soil structure degradation and soil organic matter exhaustion. Some authors applied cover on crops to avoid the raindrop impact and the surfaces wash but there is a need to develop new strategies to reduce soil losses and keep sustainable the citrus productions. The agriculture production also results in a large amount of residues than can be a resource to improve the soil cover. This has been done in road embankments, in forest land affected by wildfires and on afforestation. As a consequence of the mechanization of the agriculture, and the reduction of the draft animals (mainly horses, mules, donkeys and oxen), the straw and the pruned branches are being a residue instead of a resource in many developed countries. Straw was used as a forage and the pruned branches as a source of heat and energy but both can be used as a mulch to control the soil erosion. The pruned branches can contribute with a valuable source of nutrients and a good soil protection. The leaves of the trees, and some parts of the plants, once harvest can contribute to reduce the soil losses. Our goal is to test if a residue such as the chipped pruned branches can be transformed as a resource that will help to control the soil erosion rates. Straw has been seen as a very efficient to reduce the water losses in agriculture land, the soil losses in fire affected land, improving soil properties, but very little is done in active citrus orchards plantations. On this study, forty rainfall simulations under 55 mm h-1 rainfall intensity during one hour, were carried out on 0,25 m2 microplots: bare (n=20) and covered with chipped pruned branches (n=20). The plots covered with the chipped branches had different mulch cover; ranging from 0 to 100 % cover and from 0 g m2 to 465 g m2. The results show a positive effect of the chipped pruned branches that reduce the soil losses to 10 % of the bare soils after a mulch cover of 25 %. It shows an exponential relation between the straw cover and weight, with the sediment yield. Acknowledgements The research projects GL2008-02879/BTE, LEDDRA 243857 and RECARE FP7 n° 603498 supported this research.
2017-09-01
For the first time since the creation of the Special Forces branch in 1987, the Army authorized the creation of a new branch, the Cyber branch. With...management model. The purpose of our research is to evaluate the effectiveness of that model to recruit Cyber Operations Officers and to examine the...performance (MOPs) and measures of effectiveness (MOEs) based on data collected from: Army institutions; a survey of the Cyber Branch population; and the
Dai, Can; Luo, Wen-Jie; Gong, Yan-Bing; Liu, Fan; Wang, Zheng-Xiang
2018-04-30
Understanding resource allocation to reproduction, a key factor in life history tradeoffs, has long intrigued plant ecologists. Despite the recognized importance of understanding the movement of resources among flowers following variable pollination, the patterns of resource reallocation to plant reproductive organs have not been thoroughly addressed. In this study, we aimed to empirically explore how resources redistribute within inflorescences in response to differential pollination intensities. Using a common herb, Sagittaria trifolia, we conducted supplemental and controlled pollination for single, some, or all flowers in simple and complex inflorescences, and compared their resulting fruiting probabilities, seed production, and average seed masses. Pollen supplementation of a single flower significantly increased its fruiting probability; however, the same manipulation of an inflorescence did not increase its overall reproduction. Single pollen-supplemented flowers had a higher percentage fruit set than inflorescences receiving supplemental pollination. In complex inflorescences, supplemental pollination had no effect on the reproductive success of flowers on the lateral or main branches. We provided evidence of resource reallocation from controlled to pollen-supplemented flowers in simple inflorescences; however, resources were unlikely to be reallocated between the main and lateral branches in the complex inflorescences, suggesting that flowering branches represent integrated physiological units in S. trifolia. The results also demonstrated that single-flower supplemental pollination would exaggerate pollen limitation and lead to a biased understanding of a plant's reproductive status. © 2018 Botanical Society of America.
Disruptive selection as a driver of evolutionary branching and caste evolution in social insects.
Planqué, R; Powell, S; Franks, N R; van den Berg, J B
2016-11-01
Theory suggests that evolutionary branching via disruptive selection may be a relatively common and powerful force driving phenotypic divergence. Here, we extend this theory to social insects, which have novel social axes of phenotypic diversification. Our model, built around turtle ant (Cephalotes) biology, is used to explore whether disruptive selection can drive the evolutionary branching of divergent colony phenotypes that include a novel soldier caste. Soldier evolution is a recurrent theme in social insect diversification that is exemplified in the turtle ants. We show that phenotypic mutants can gain competitive advantages that induce disruptive selection and subsequent branching. A soldier caste does not generally appear before branching, but can evolve from subsequent competition. The soldier caste then evolves in association with specialized resource preferences that maximize defensive performance. Overall, our model indicates that resource specialization may occur in the absence of morphological specialization, but that when morphological specialization evolves, it is always in association with resource specialization. This evolutionary coupling of ecological and morphological specialization is consistent with recent empirical evidence, but contrary to predictions of classical caste theory. Our model provides a new theoretical understanding of the ecology of caste evolution that explicitly considers the process of adaptive phenotypic divergence and diversification. © 2016 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2016 European Society For Evolutionary Biology.
Resource Constrained Planning of Multiple Projects with Separable Activities
NASA Astrophysics Data System (ADS)
Fujii, Susumu; Morita, Hiroshi; Kanawa, Takuya
In this study we consider a resource constrained planning problem of multiple projects with separable activities. This problem provides a plan to process the activities considering a resource availability with time window. We propose a solution algorithm based on the branch and bound method to obtain the optimal solution minimizing the completion time of all projects. We develop three methods for improvement of computational efficiency, that is, to obtain initial solution with minimum slack time rule, to estimate lower bound considering both time and resource constraints and to introduce an equivalence relation for bounding operation. The effectiveness of the proposed methods is demonstrated by numerical examples. Especially as the number of planning projects increases, the average computational time and the number of searched nodes are reduced.
RIAD visual imaging branch assessment
NASA Technical Reports Server (NTRS)
Beam, Sherilee F.
1993-01-01
Every year the demand to visualize research efforts increases. The visualization provides the means to effectively analyze data and present the results. The technology support for visualization is constantly changing, improving, and being made available to users everywhere. As such, many researchers are entering into the practice of doing their own visualization in house - sometimes successfully, sometimes not. In an effort to keep pace with the visualization needs of researchers, the Visual Imaging Branch of the Research, Information, and Applications Division at NASA Langley Research Center has conducted an investigation into the current status of imaging technology and imaging production throughout the various research branches at the center. This investigation will allow the branch to evaluate its current resources and personnel in an effort to identify future directions for meeting the needs of the researchers at the center. The investigation team, which consisted of the ASEE fellow, the head of the video section, and the head of the photo section, developed an interview format that could be accomplished during a short interview period with researchers, and yet still provide adequate statistics about items such as in-house equipment and usage.
USSR Report, Military Affairs, Aviation and Cosmonautics, No. 6, June 1986
1986-10-09
Economic and Social Development of the USSR for 1986-1990 and the Period Up to the Year 2000. The 12th Five-Year Plan plays a most important role in...achievement of an optimal combination of branch and territorial economic management and integrated economic and social development of republics and... Social Development of the USSR for 1986-1990 and the Period Up to the Year 2000. During these 15 years it is planned to double the volume of resources
3 CFR - Long-Term Gulf Coast Restoration Support Plan
Code of Federal Regulations, 2011 CFR
2011-01-01
... President (collectively, executive branch components). Specifically, I direct the following: Section 1. As..., science-based restoration of the ecosystem and environment, public health and safety efforts, and support... memorandum, executive branch components shall make available information and other resources, including...
Bowers, Janice E.
2006-01-01
The capacity of individual branches to store water and fix carbon can have profound effects on inflorescence size and architecture, thus on floral display, pollination, and fecundity. Mixed regression was used to investigate the relation between branch length, a proxy for plant resources, and floral display of Fouquieria splendens (ocotillo), a woody, candelabraform shrub of wide distribution in arid North America. Long branches produced three times as many flowers as short branches, regardless of overall plant size. Long branches also had more complex panicles with more cymes and cyme types than short branches; thus, branch length also influenced inflorescence architecture. Within panicles, increasing the number of cymes by one unit added about two flowers, whereas increasing the number of cyme types by one unit added about 21 flowers. Because flower production is mediated by branch length, and because most plants have branches of various lengths, the floral display of individual plants necessarily encompasses a wide range of inflorescence size and structure. ?? Springer 2006.
Aono, Masashi; Kim, Song-Ju; Hara, Masahiko; Munakata, Toshinori
2014-03-01
The true slime mold Physarum polycephalum, a single-celled amoeboid organism, is capable of efficiently allocating a constant amount of intracellular resource to its pseudopod-like branches that best fit the environment where dynamic light stimuli are applied. Inspired by the resource allocation process, the authors formulated a concurrent search algorithm, called the Tug-of-War (TOW) model, for maximizing the profit in the multi-armed Bandit Problem (BP). A player (gambler) of the BP should decide as quickly and accurately as possible which slot machine to invest in out of the N machines and faces an "exploration-exploitation dilemma." The dilemma is a trade-off between the speed and accuracy of the decision making that are conflicted objectives. The TOW model maintains a constant intracellular resource volume while collecting environmental information by concurrently expanding and shrinking its branches. The conservation law entails a nonlocal correlation among the branches, i.e., volume increment in one branch is immediately compensated by volume decrement(s) in the other branch(es). Owing to this nonlocal correlation, the TOW model can efficiently manage the dilemma. In this study, we extend the TOW model to apply it to a stretched variant of BP, the Extended Bandit Problem (EBP), which is a problem of selecting the best M-tuple of the N machines. We demonstrate that the extended TOW model exhibits better performances for 2-tuple-3-machine and 2-tuple-4-machine instances of EBP compared with the extended versions of well-known algorithms for BP, the ϵ-Greedy and SoftMax algorithms, particularly in terms of its short-term decision-making capability that is essential for the survival of the amoeba in a hostile environment. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.
Fort Collins Science Center Ecosystem Dynamics Branch
Wilson, Jim; Melcher, C.; Bowen, Z.
2009-01-01
Complex natural resource issues require understanding a web of interactions among ecosystem components that are (1) interdisciplinary, encompassing physical, chemical, and biological processes; (2) spatially complex, involving movements of animals, water, and airborne materials across a range of landscapes and jurisdictions; and (3) temporally complex, occurring over days, weeks, or years, sometimes involving response lags to alteration or exhibiting large natural variation. Scientists in the Ecosystem Dynamics Branch of the U.S. Geological Survey, Fort Collins Science Center, investigate a diversity of these complex natural resource questions at the landscape and systems levels. This Fact Sheet describes the work of the Ecosystems Dynamics Branch, which is focused on energy and land use, climate change and long-term integrated assessments, herbivore-ecosystem interactions, fire and post-fire restoration, and environmental flows and river restoration.
NASA Astrophysics Data System (ADS)
Papelniuk, Oksana
2017-10-01
The author studies innovative activity of enterprises and carries out the classification of conditions and factors of construction enterprises’ innovative activity, and conducts systematization of specific features of this innovative activity. On the basis of statistical data on structure and dynamics of innovations the author carries out the research with the use of methods of economic-mathematical modelling in order to offer the approach which will allow construction enterprises to define the directions of innovative activity for achievement of a resource-saving and energy efficiency in construction sector.
Selected Resources and Bibliography
ERIC Educational Resources Information Center
New Directions for Higher Education, 2011
2011-01-01
This chapter provides an annotated bibliography of resources pertaining to international branch campuses (IBCs). This collection of references has been selected to represent the breadth of emerging scholarship on cross-border higher education and is intended to provide further resources on a range of concerns surrounding cross-border higher…
78 FR 25974 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-03
... Human Resources Command, Reclassification Management Branch, 2461 Eisenhower Avenue, Alexandria, VA... Files. System location: Commander, U.S. Army Human Resources Command, ATTN: AHRC-PED-A, 2461 Eisenhower... Human Resources Command, ATTN: AHRC-PED-A, 2461 Eisenhower Avenue, Alexandria, VA 23321-0482 for Army...
75 FR 21640 - National Cancer Institute; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-26
..., Resources and Training Review Branch, Division of Extramural Activities, National Cancer Institute, 6116....D., PhD, Scientific Review Officer, Research Programs Review Branch, Division of Extramural... & Tissue Biology P01. Date: May 26-28, 2010. Time: 5 p.m. to 5 p.m. Agenda: To review and evaluate grant...
Pollen limitation of reproductive effort in willows.
Fox, John F
1992-05-01
Pollen limitation of seed set differs from resource limitation in its implications for the evolution of floral traits. Willow flowers attract insects, but also abundantly produce wind-dispersed pollen. I demonstrated pollen limitation in single branches bearing 2-4 inflorescences (catkins) in a field experiment with five species by artificially increasing or decreasing the pollen load. Because the responses by single branches might be explained by diversion of resources to better-pollinated branches within a plant, a second experiment with one species tested both pollen limitation of whole plants and the autonomy of catkins. Seed set of single willow catkins is unaffected by experimental alterations of seed set in other catkins on the same plant. Hand-pollination of single catkins and of whole plants increased seed set to the same degree, suggesting there is little or no competition for resources between catkins only 5-10 cm apart. Thus, seed set in willows appears to be pollen limited, favoring insect pollination and the evolution of entomophilous traits. The data support previous views that willows have a dual pollination system utilizing wind and insects.
77 FR 35698 - Secretary's Advisory Committee on Heritable Disorders in Newborns and Children
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-14
...), SACHDNC; and, Chief, Genetic Services Branch, Maternal and Child Health Bureau, Health Resources and...., Genetic Services Branch, Maternal and Child Health Bureau, HRSA, at [email protected] or (301) 443-1080. A..., or at risk for, heritable disorders; and (b) enhancing the ability of the State and local health...
Kim, Song-Ju; Aono, Masashi; Hara, Masahiko
2010-07-01
We propose a model - the "tug-of-war (TOW) model" - to conduct unique parallel searches using many nonlocally-correlated search agents. The model is based on the property of a single-celled amoeba, the true slime mold Physarum, which maintains a constant intracellular resource volume while collecting environmental information by concurrently expanding and shrinking its branches. The conservation law entails a "nonlocal correlation" among the branches, i.e., volume increment in one branch is immediately compensated by volume decrement(s) in the other branch(es). This nonlocal correlation was shown to be useful for decision making in the case of a dilemma. The multi-armed bandit problem is to determine the optimal strategy for maximizing the total reward sum with incompatible demands, by either exploiting the rewards obtained using the already collected information or exploring new information for acquiring higher payoffs involving risks. Our model can efficiently manage the "exploration-exploitation dilemma" and exhibits good performances. The average accuracy rate of our model is higher than those of well-known algorithms such as the modified -greedy algorithm and modified softmax algorithm, especially, for solving relatively difficult problems. Moreover, our model flexibly adapts to changing environments, a property essential for living organisms surviving in uncertain environments.
Ishihara, Masae Iwamoto; Kikuzawa, Kihachiro
2009-01-01
Backgrounds and Aims Shoot demography affects the growth of the tree crown and the number of leaves on a tree. Masting may cause inter-annual and spatial variation in shoot demography of mature trees, which may in turn affect the resource budget of the tree. The aim of this study was to evaluate the effect of masting on the temporal and spatial variations in shoot demography of mature Betula grossa. Methods The shoot demography was analysed in the upper and lower parts of the tree crown in mature trees and saplings over 7 years. Mature trees and saplings were compared to differentiate the effect of masting from the effect of exogenous environment on shoot demography. The fate of different shoot types (reproductive, vegetative, short, long), shoot length and leaf area were investigated by monitoring and by retrospective survey using morphological markers on branches. The effects of year and branch position on demographic parameters were evaluated. Key Results Shoot increase rate, production of long shoots, bud mortality, length of long shoots and leaf area of a branch fluctuated periodically from year to year in mature trees over 7 years, in which two masting events occurred. Branches within a crown showed synchronized annual variation, and the extent of fluctuation was larger in the upper branches than the lower branches. Vegetative shoots varied in their bud differentiation each year and contributed to the dynamic shoot demography as much as did reproductive shoots, suggesting physiological integration in shoot demography through hormonal regulation and resource allocation. Conclusions Masting caused periodic annual variation in shoot demography of the mature trees and the effect was spatially variable within a tree crown. Since masting is a common phenomenon among tree species, annual variation in shoot demography and leaf area should be incorporated into resource allocation models of mature masting trees. PMID:19734164
75 FR 20427 - Agency Information Collection (Reasonable Accommodation) Activities Under OMB Review
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-19
... Collection (Reasonable Accommodation) Activities Under OMB Review AGENCY: Office of Human Resources and... Reduction Act (PRA) of 1995 (44 U.S.C. 3501-21), this notice announces that the Office of Human Resources... VA's OMB Desk Officer, OMB Human Resources and Housing Branch, New Executive Office Building, Room...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-24
... Concerning Applicant for Employment) Activities Under OMB Review AGENCY: Office of Human Resources and... Reduction Act (PRA) of 1995 (44 U.S.C. 3501-3521), this notice announces that the Office of Human Resources... OMB Desk Officer, OMB Human Resources and Housing Branch, New Executive Office Building, Room 10235...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-13
... (Complaint of Employment Discrimination) Activity Under OMB Review AGENCY: Office of Human Resources and... Reduction Act (PRA) of 1995 (44 U.S.C. 3501-21), this notice announces that the Office of Human Resources... OMB Desk Officer, OMB Human Resources and Housing Branch, New Executive Office Building, Room 10235...
Building science-based groundwater tools and capacity in Armenia for the Ararat Basin
Carter, Janet M.; Valder, Joshua F.; Anderson, Mark T.; Meyer, Patrick; Eimers, Jo L.
2016-05-18
The U.S. Geological Survey (USGS) and U.S. Agency for International Development (USAID) began a study in 2016 to help build science-based groundwater tools and capacity for the Ararat Basin in Armenia. The growth of aquaculture and other uses in the Ararat Basin has been accompanied by increased withdrawals of groundwater, which has resulted in a reduction of artesian conditions (decreased springflow, well discharges, and water levels) including loss of flowing wells in many places (Armenia Branch of Mendez England and Associates, 2014; Yu and others, 2015). This study is in partnership with USAID/Armenia in the implementation of its Science, Technology, Innovation, and Partnerships (STIP) effort through the Advanced Science and Partnerships for Integrated Resource Development (ASPIRED) program and associated partners, including the Government of Armenia, Armenia’s Hydrogeological Monitoring Center, and the USAID Global Development Lab and its GeoCenter. Scientific tools will be developed through this study that groundwater-resource managers, such as those in the Ministry of Nature Protection, in Armenia can use to understand and predict the consequences of their resource management decisions.
North Branch Potomac River Basin mine drainage study. Phase I. Baseline survey. Final report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1977-05-06
This baseline survey of the mine drainage and related water resources of the North Branch Potomac River Basin established the extent, magnitude, and effects of coal mine drainage pollution. Alternative abatement and reclamation solutions were considered. The study included an analysis of socioeconomic and environmental conditions as related to the mine drainage problem.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-01
... action alternatives and the No Action Alternative. Natural, cultural, and socioeconomic resource impacts.... Cohn, Chief, or Issac J. Gaston, Site Selection Specialist, Capacity Planning and Site Selection Branch..., Capacity Planning and Site Selection Branch. [FR Doc. 2011-1817 Filed 1-31-11; 8:45 am] BILLING CODE P ...
1982-08-01
though the two groups were different in terms of SC!I scientific interests and academic orientation scores (the aviation supply sample scored higher on...51 Chemists/Physicists 50 MARINE OFFICERS- COMUNICATION 49 MARINE OFFICERS-DATA SYSTEMS 48 Engineers 47 Biologists 46 Systems Analysts/Computer...Base ( Scientific and Technical Information Office) Commander, Air Force Human Resources Laboratory, Lowry Air Force Base (Technical Training Branch
ERIC Educational Resources Information Center
Association of American Universities, 2011
2011-01-01
This guide includes the following: higher education and related associations; advocacy organizations and coalitions of interest to research universities; explanations of acronyms and terms commonly used in the university community; web links to government resources and agencies; Executive and Legislative Branch offices; and key federal…
On the evolution of specialization with a mechanistic underpinning in structured metapopulations.
Nurmi, Tuomas; Parvinen, Kalle
2008-03-01
We analyze the evolution of specialization in resource utilization in a discrete-time metapopulation model using the adaptive dynamics approach. The local dynamics in the metapopulation are based on the Beverton-Holt model with mechanistic underpinnings. The consumer faces a trade-off in the abilities to consume two resources that are spatially heterogeneously distributed to patches that are prone to local catastrophes. We explore the factors favoring the spread of generalist or specialist strategies. Increasing fecundity or decreasing catastrophe probability favors the spread of the generalist strategy and increasing environmental heterogeneity enlarges the parameter domain where the evolutionary branching is possible. When there are no catastrophes, increasing emigration diminishes the parameter domain where the evolutionary branching may occur. Otherwise, the effect of emigration on evolutionary dynamics is non-monotonous: both small and large values of emigration probability favor the spread of the specialist strategies whereas the parameter domain where evolutionary branching may occur is largest when the emigration probability has intermediate values. We compare how different forms of spatial heterogeneity and different models of local growth affect the evolutionary dynamics. We show that even small changes in the resource dynamics may have outstanding evolutionary effects to the consumers.
A proposed biophysical approach to Visual absorption capability (VAC)
W. C. Yeomans
1979-01-01
In British Columbia, visual analysis is in its formative stages and has only recently been accepted by Government as a resource component, notably within the Resource Analysis Branch, Ministry of Environment. Visual absorption capability (VAC), is an integral factor in visual resource assessment. VAC is examined by the author in the degree to which it relates to...
Bowen, Zachary H.; Melcher, Cynthia P.; Wilson, Juliette T.
2013-01-01
The Ecosystem Dynamics Branch of the Fort Collins Science Center offers an interdisciplinary team of talented and creative scientists with expertise in biology, botany, ecology, geology, biogeochemistry, physical sciences, geographic information systems, and remote-sensing, for tackling complex questions about natural resources. As demand for natural resources increases, the issues facing natural resource managers, planners, policy makers, industry, and private landowners are increasing in spatial and temporal scope, often involving entire regions, multiple jurisdictions, and long timeframes. Needs for addressing these issues include (1) a better understanding of biotic and abiotic ecosystem components and their complex interactions; (2) the ability to easily monitor, assess, and visualize the spatially complex movements of animals, plants, water, and elements across highly variable landscapes; and (3) the techniques for accurately predicting both immediate and long-term responses of system components to natural and human-caused change. The overall objectives of our research are to provide the knowledge, tools, and techniques needed by the U.S. Department of the Interior, state agencies, and other stakeholders in their endeavors to meet the demand for natural resources while conserving biodiversity and ecosystem services. Ecosystem Dynamics scientists use field and laboratory research, data assimilation, and ecological modeling to understand ecosystem patterns, trends, and mechanistic processes. This information is used to predict the outcomes of changes imposed on species, habitats, landscapes, and climate across spatiotemporal scales. The products we develop include conceptual models to illustrate system structure and processes; regional baseline and integrated assessments; predictive spatial and mathematical models; literature syntheses; and frameworks or protocols for improved ecosystem monitoring, adaptive management, and program evaluation. The descriptions in this fact sheet provide snapshots of our three research emphases, followed by descriptions of select current projects.
NASA Astrophysics Data System (ADS)
McCleery, W. Tyler; Mohd-Radzman, Nadiatul A.; Grieneisen, Veronica A.
Cells within tissues can be regarded as autonomous entities that respond to their local environment and signaling from neighbors. Cell coordination is particularly important in plants, where root architecture must strategically invest resources for growth to optimize nutrient acquisition. Thus, root cells are constantly adapting to environmental cues and neighbor communication in a non-linear manner. To explain such plasticity, we view the root as a swarm of coupled multi-cellular structures, ''metamers'', rather than as a continuum of identical cells. These metamers are individually programmed to achieve a local objective - developing a lateral root primordia, which aids in local foraging of nutrients. Collectively, such individual attempts may be halted, structuring root architecture as an emergent behavior. Each metamer's decision to branch is coordinated locally and globally through hormone signaling, including processes of controlled diffusion, active polar transport, and dynamic feedback. We present a physical model of the signaling mechanism that coordinates branching decisions in response to the environment. This work was funded by the European Commission 7th Framework Program, Project No. 601062, SWARM-ORGAN.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, Cong; Luo, Xiaolan; Li, Tao
2014-01-01
Environmentally friendly biopolyols have been produced with crude glycerol as the sole feedstock using a one-pot thermochemical conversion process without the addition of extra catalysts and reagents. Structural features of these biopolyols were characterized by rheology analysis. Rigid polyurethane (PU) foams were obtained from these crude glycerol-based biopolyols and the foaming mechanism was explored. Investigations revealed that partial carbonyl groups hydrogen-bonded with NeH were replaced by aromatic rings after the introduction of branched fatty acid ester chains in the “urea rich” phase, and that distinct microphases had formed in the foams. Studies showed that branched fatty acid ester chains inmore » the biopolyols played an important role in reducing the degree of microphase separation and stabilizing bubbles during foaming processes. PU foams with thermal conductivity comparable to commercial products made from petroleum-based polyols were obtained. These studies show the potential for development of PU foams based on crude glycerol, a renewable resource.« less
75 FR 2554 - Advisory Committee on Heritable Disorders in Newborns and Children
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-15
... FURTHER INFORMATION CONTACT: Ms. Alaina Harris, Genetic Services Branch, Maternal and Child Health Bureau... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Advisory Committee on Heritable Disorders in Newborns and Children AGENCY: Health Resources and Services...
Performance optimization of a hybrid micro-grid based on double-loop MPPT and SVC-MERS
NASA Astrophysics Data System (ADS)
Wei, Yewen; Hou, Xilun; Zhang, Xiang; Xiong, Shengnan; Peng, Fei
2018-02-01
With ever-increasing concerns on environmental pollution and energy shortage, the development of renewable resource has attracted a lot of attention. This paper first reviews both the wind and photovoltaic (PV) generation techniques and approaches of micro-grid voltage control. Then, a novel islanded micro-grid, which consists of wind & PV generation and hybrid-energy storage device, is built for application to remote and isolated areas. For the PV power generation branch, a double- maximum power point tracking (MPPT) technique is developed to trace the sunlight and regulate the tilt angle of PV panels. For wind-power generation branch, squirrel cage induction generator (SCIG) is used as its simple structure, robustness and less cost. In order to stabilize the output voltage of SCIGs, a new Static Var Compensator named magnetic energy recovery switch (SVC-MERS) is applied. Finally, experimental results confirm that both of the proposed methods can improve the efficiency of PV power generation and voltage stability of the micro-grid, respectively.
Integrating Chemistry: Crossing the Millennium Divide.
Housecroft, Catherine E
2018-02-01
A personal account of the development of two University level chemistry books is presented. The account focuses on ways to integrate the traditional branches of chemistry into a textbook that captures the imagination of students and relates chemical principles and fundamental topics to environmental, medicinal, biological and industrial applications. The ways in which teaching methods have changed over two decades and how web-based resources can be used to improve the communication of chemical (in particular structural) concepts are highlighted.
NASA Astrophysics Data System (ADS)
Adler, David S.; Workman, William M., III; Chance, Don
2004-09-01
The Science and Mission Scheduling Branch (SMSB) of the Space Telescope Science Institute (STScI) historically operated exclusively under VMS. Due to diminished support for VMS-based platforms at STScI, SMSB recently transitioned to Unix operations. No additional resources were available to the group; the project was SMSB's to design, develop, and implement. Early decisions included the choice of Python as the primary scripting language; adoption of Object-Oriented Design in the development of base utilities; and the development of a Python utility to interact directly with the Sybase database. The project was completed in January 2004 with the implementation of a GUI to generate the Command Loads that are uplinked to HST. The current tool suite consists of 31 utilities and 271 tools comprising over 60,000 lines of code. In this paper, we summarize the decision-making process used to determine the primary scripting language, database interface, and code management library. We also describe the finished product and summarize lessons learned along the way to completing the project.
Contingency Planning for Planetary Rovers
NASA Technical Reports Server (NTRS)
Dearden, Richard; Meuleau, Nicolas; Ramakrishnan, Sailesh; Smith, David; Washington, Rich; Clancy, Daniel (Technical Monitor)
2002-01-01
There has been considerable work in AI on planning under uncertainty. But this work generally assumes an extremely simple model of action that does not consider continuous time and resources. These assumptions are not reasonable for a Mars rover, which must cope with uncertainty about the duration of tasks, the power required, the data storage necessary, along with its position and orientation. In this paper, we outline an approach to generating contingency plans when the sources of uncertainty involve continuous quantities such as time and resources. The approach involves first constructing a "seed" plan, and then incrementally adding contingent branches to this plan in order to improve utility. The challenge is to figure out the best places to insert contingency branches. This requires an estimate of how much utility could be gained by building a contingent branch at any given place in the seed plan. Computing this utility exactly is intractable, but we outline an approximation method that back propagates utility distributions through a graph structure similar to that of a plan graph.
Incremental Contingency Planning
NASA Technical Reports Server (NTRS)
Dearden, Richard; Meuleau, Nicolas; Ramakrishnan, Sailesh; Smith, David E.; Washington, Rich
2003-01-01
There has been considerable work in AI on planning under uncertainty. However, this work generally assumes an extremely simple model of action that does not consider continuous time and resources. These assumptions are not reasonable for a Mars rover, which must cope with uncertainty about the duration of tasks, the energy required, the data storage necessary, and its current position and orientation. In this paper, we outline an approach to generating contingency plans when the sources of uncertainty involve continuous quantities such as time and resources. The approach involves first constructing a "seed" plan, and then incrementally adding contingent branches to this plan in order to improve utility. The challenge is to figure out the best places to insert contingency branches. This requires an estimate of how much utility could be gained by building a contingent branch at any given place in the seed plan. Computing this utility exactly is intractable, but we outline an approximation method that back propagates utility distributions through a graph structure similar to that of a plan graph.
Toolboxes for a standardised and systematic study of glycans
2014-01-01
Background Recent progress in method development for characterising the branched structures of complex carbohydrates has now enabled higher throughput technology. Automation of structure analysis then calls for software development since adding meaning to large data collections in reasonable time requires corresponding bioinformatics methods and tools. Current glycobioinformatics resources do cover information on the structure and function of glycans, their interaction with proteins or their enzymatic synthesis. However, this information is partial, scattered and often difficult to find to for non-glycobiologists. Methods Following our diagnosis of the causes of the slow development of glycobioinformatics, we review the "objective" difficulties encountered in defining adequate formats for representing complex entities and developing efficient analysis software. Results Various solutions already implemented and strategies defined to bridge glycobiology with different fields and integrate the heterogeneous glyco-related information are presented. Conclusions Despite the initial stage of our integrative efforts, this paper highlights the rapid expansion of glycomics, the validity of existing resources and the bright future of glycobioinformatics. PMID:24564482
76 FR 31617 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-01
... Emphasis Panel, Utilization of a Human Lung Tissue Resource for Vascular Research. Date: June 23, 2011... Research; 93.838, Lung Diseases Research; 93.839, Blood Diseases and Resources Research, National... Sunnarborg, PhD, Scientific Review Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute...
Management of Federal Information Resources. Circular No. A-130.
ERIC Educational Resources Information Center
Office of Management and Budget, Washington, DC.
Directed to the heads of executive departments and establishments, this circular establishes policy for the management of federal information resources. Procedural and analytic guidelines for implemented aspects of these policies are included as appendices. The policies apply to the information activities of all agencies of the executive branch of…
Branching Out: The North Carolina Forest Stewardship Activity Guide.
ERIC Educational Resources Information Center
Chesson, Gail
Stewardship is the responsibility of individuals to maintain and improve their natural resources and surroundings. The Forest Stewardship Program (FSP) in North Carolina aims at enhancing the management of all forest resources on private lands. This activity guide is designed to help youth appreciate and understand forests and natural…
Communist China’s Progress in Inorganic, Organic, and Physical Chemistry in Recent Decade
1960-03-16
situation, develp t ms bin- dered. ?ollwving the revival of nastieal tahvoloe In World War I, Inorganic chemstry , lMke other branches of che•strj, mde seem...in high-density sam~ples." Looking back at the devolou t of our inorganic chemstry in the pest decadse, we believe that today’s echievemt from a blank...8217, and rich chemical resources are Iamting for. solutions, Therefore, Our Inorganic chemstry workers must bear in mind the development of Chinats
Social science and Sozialwissenschaft: Categorical and institutional boundaries of knowledge.
Sonnert, Gerhard
2018-05-16
This article explores how linguistic categories affect boundary work in scholarly knowledge production. Whereas the German language knows the unified concept of Wissenschaft for all branches of scholarship represented at universities, the English language separates science from the arts or humanities and does not commonly engage an overarching concept. This has had consequences for American social science, which are traced both in the discourse shaping its development and in the deployment and distribution of institutional resources. © 2018 Wiley Periodicals, Inc.
NASA Astrophysics Data System (ADS)
Yamanaka, Shigeru; Sato, Kanna; Ito, Fuyu; Komatsubara, Satoshi; Ohata, Hiroshi; Yoshino, Katsumi
2012-02-01
This research deals with detailed analyses of silica and lignin distribution in horsetail with special reference to mechanical strength. Scanning electron images of a cross-section of an internode showed silica deposited densely only around the outer epidermis. Detailed histochemical analyses of lignin showed no lignin deposition in the silica-rich outer internodes of horsetail, while a characteristic lignin deposition was noticed in the vascular bundle in inner side of internodes. To analyze the structure of horsetail from a mechanical viewpoint, we calculated the response of a model structure of horsetail to a mechanical force applied perpendicularly to the long axis by a finite element method. We found that silica distributed in the outer epidermis may play the major structural role, with lignin's role being limited ensuring that the vascular bundle keep waterproof. These results were in contrast to more modern tall trees like gymnosperms, for which lignin provides mechanical strength. Lignin has the advantage of sticking to cellulose, hemicellulose, and other materials. Such properties make it possible for plants containing lignin to branch. Branching of tree stems aids in competing for light and other atmospheric resources. This type of branching was impossible for ancient horsetails, which relied on the physical properties of silica. From the evolutional view points, over millennia in trees with high lignin content, true branching, and many chlorophyll-containing leaves developed.
Nautiyal, Sunil; Kaechele, Harald
2009-06-01
The concept of ecosystem conservation as a broad theme came into existence during the 1970s under the Man and Biosphere Programme (MAB) of the United Nations Educational, Scientific and Cultural Organization (UNESCO). The Indian Government followed this approach and chose the method to segregate the landscape for conservation of the ecosystem as well as for the development of the local economy and its people. We have examined the effect of this policy and concurrently developed a theoretical modeling approach to understand how human behavior is changing under shifting political, socioeconomic and environmental conditions. A specific focus has been on how the landscape is changing in the mountains of the Indian Himalayan region where about 10% of the total geographical area is converted into protected landscape for conservation of biodiversity. For local people living in the Himalayan mountains in India, agriculture is the main land use activity and is strongly linked to the forests in providing sustainability. There are several branches in the rural ecosystems where the local people's economy was centered. These include agriculture, animal husbandry, medicinal and aromatic plants cultivation, forest resource collection, tourism and other occupations. The greatest proportion of the population was engaged in the agriculture sector, whose contribution is high in the rural economy (61%); followed by animal husbandry (19%), forest resource collection for economic gain (18%), and medicinal and aromatic plants cultivation (1.5%). However, three decades ago the animal husbandry branch of the rural ecosystem was contributing the maximum share towards rural household income (40%) followed by tourism (35.2%), and lastly agriculture (14%). The desire of farmers to secure the optimum output from agricultural land use has resulted in an increase for resource collection from the forests. The people's perception (n = 1,648) regarding overall changes occurring in the region was varied and most showed that the current trend within rural ecosystems has emerged because of the implementation of conservation policies/creation of national park and biosphere reserve (80%), followed by limitation (22%), climate (20%), population growth (7%), national economy (10%) and least by socioeconomic change (5%). The theoretical agent model developed here draws attention to agent/farmer behavior and land resource use for his livelihood in the temporal dimension. The current study would be helpful to introduce new approaches for the development of the methodological and theoretical aspects associated with the complex human and ecosystem interactions in the Himalayan mountains for sustainable landscape development.
Proposed Bak Stabilization Tennessee River, River Mile 466.2 - 466.5 Hamilton County, Tennessee
2013-04-01
Project Planning Branch EA Preparation Mitzy Schaney, Archaeologist Project Planning Branch Cultural Resources Preparation Ramune Morales, Project...addressed in our evaluation. Please contact Mitzy L. Schaney at (615) 736-2268 or mitzy.l.schaney@usace.army.mil if you require additional...of the phased compliance approach. Also include any concerns you would like addressed in our evaluation. Please contact Mitzy L. Schaney at (615) 736
Wu, Hao; Wan, Zhong
2018-02-01
In this paper, a multiobjective mixed-integer piecewise nonlinear programming model (MOMIPNLP) is built to formulate the management problem of urban mining system, where the decision variables are associated with buy-back pricing, choices of sites, transportation planning, and adjustment of production capacity. Different from the existing approaches, the social negative effect, generated from structural optimization of the recycling system, is minimized in our model, as well as the total recycling profit and utility from environmental improvement are jointly maximized. For solving the problem, the MOMIPNLP model is first transformed into an ordinary mixed-integer nonlinear programming model by variable substitution such that the piecewise feature of the model is removed. Then, based on technique of orthogonal design, a hybrid heuristic algorithm is developed to find an approximate Pareto-optimal solution, where genetic algorithm is used to optimize the structure of search neighborhood, and both local branching algorithm and relaxation-induced neighborhood search algorithm are employed to cut the searching branches and reduce the number of variables in each branch. Numerical experiments indicate that this algorithm spends less CPU (central processing unit) time in solving large-scale regional urban mining management problems, especially in comparison with the similar ones available in literature. By case study and sensitivity analysis, a number of practical managerial implications are revealed from the model. Since the metal stocks in society are reliable overground mineral sources, urban mining has been paid great attention as emerging strategic resources in an era of resource shortage. By mathematical modeling and development of efficient algorithms, this paper provides decision makers with useful suggestions on the optimal design of recycling system in urban mining. For example, this paper can answer how to encourage enterprises to join the recycling activities by government's support and subsidies, whether the existing recycling system can meet the developmental requirements or not, and what is a reasonable adjustment of production capacity.
The dynamic relationship between plant architecture and competition
Ford, E. David
2014-01-01
In this review, structural and functional changes are described in single-species, even-aged, stands undergoing competition for light. Theories of the competition process as interactions between whole plants have been advanced but have not been successful in explaining these changes and how they vary between species or growing conditions. This task now falls to researchers in plant architecture. Research in plant architecture has defined three important functions of individual plants that determine the process of canopy development and competition: (i) resource acquisition plasticity; (ii) morphogenetic plasticity; (iii) architectural variation in efficiency of interception and utilization of light. In this review, this research is synthesized into a theory for competition based on five groups of postulates about the functioning of plants in stands. Group 1: competition for light takes place at the level of component foliage and branches. Group 2: the outcome of competition is determined by the dynamic interaction between processes that exert dominance and processes that react to suppression. Group 3: species differences may affect both exertion of dominance and reaction to suppression. Group 4: individual plants may simultaneously exhibit, in different component parts, resource acquisition and morphogenetic plasticity. Group 5: mortality is a time-delayed response to suppression. Development of architectural models when combined with field investigations is identifying research needed to develop a theory of architectural influences on the competition process. These include analyses of the integration of foliage and branch components into whole-plant growth and precise definitions of environmental control of morphogenetic plasticity and its interaction with acquisition of carbon for plant growth. PMID:24987396
The dynamic relationship between plant architecture and competition.
Ford, E David
2014-01-01
In this review, structural and functional changes are described in single-species, even-aged, stands undergoing competition for light. Theories of the competition process as interactions between whole plants have been advanced but have not been successful in explaining these changes and how they vary between species or growing conditions. This task now falls to researchers in plant architecture. Research in plant architecture has defined three important functions of individual plants that determine the process of canopy development and competition: (i) resource acquisition plasticity; (ii) morphogenetic plasticity; (iii) architectural variation in efficiency of interception and utilization of light. In this review, this research is synthesized into a theory for competition based on five groups of postulates about the functioning of plants in stands. Group 1: competition for light takes place at the level of component foliage and branches. Group 2: the outcome of competition is determined by the dynamic interaction between processes that exert dominance and processes that react to suppression. Group 3: species differences may affect both exertion of dominance and reaction to suppression. Group 4: individual plants may simultaneously exhibit, in different component parts, resource acquisition and morphogenetic plasticity. Group 5: mortality is a time-delayed response to suppression. Development of architectural models when combined with field investigations is identifying research needed to develop a theory of architectural influences on the competition process. These include analyses of the integration of foliage and branch components into whole-plant growth and precise definitions of environmental control of morphogenetic plasticity and its interaction with acquisition of carbon for plant growth.
Staff Clinicians | Center for Cancer Research
The Neuro-Oncology Branch (NOB), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH) is seeking staff clinicians to provide high-quality patient care for individuals with primary central nervous system (CNS) malignancies. The NOB is comprised of a multidisciplinary team of physicians, healthcare providers, and scientists who are dedicated to developing new therapies and improving outcomes for patients with primary brain and spinal cord tumors. The NOB is one of the first trans-institutional initiatives at the National Institutes of Health. The Branch is focused on developing an integrated clinical, translational, and basic research program that engages the strengths and resources of the National Cancer Institutes (NCI) and the National Institutes of Neurological Disorders and Stroke (NINDS) for the purpose of developing novel experimental therapeutics for individuals with primary central nervous system (CNS) malignancies. About NCI's Center for Cancer Research The Center for Cancer Research (CCR) is the intramural research component of the National Cancer Institute (NCI). CCR’s enabling infrastructure facilitates clinical studies at the NIH Clinical Center, the world’s largest dedicated clinical research complex; provides extensive opportunities for collaboration; and allows scientists and clinicians to undertake high-risk, high-impact laboratory- and clinic-based investigations. Investigators are supported by a wide array of intellectual, technological, and research resources, including surgical and pathology facilities, animal facilities, and dedicated, high-quality technology cores in areas such as imaging/microscopy, chemistry/purification, mass spectrometry, flow cytometry, genomics/DNA sequencing, transgenics and knock-out mice, arrays/molecular profiling, and human genetics/bioinformatics. For an overview of CCR, please visit http://ccr.cancer.gov/.
Fort Collins Science Center: Policy Analysis and Science Assistance
Lamb, Berton L.
2004-01-01
PASA's mission is to integrate biological, social, and economic research so that resource managers can use the resulting information to make informed decisions and resolve resource management conflicts. PASA scientists pursue and conduct scientific analyses that help agencies and Native American tribes to (1) identify impending policy controversies and areas where social and natural science research is needed to address future policy questions; (2) develop methods and approaches to assist researchers in preparing scientific evidence; (3) assess habitat alteration in a manner consistent with policy needs; and (4) evaluate policy options. Branch scientists also evaluate policy options (e.g., effects of different land treatments, fish and wildlife management practices, or visitor/recreation management practices) in response to specific questions faced by policymakers and managers.
Ecological effects of contaminants in McCoy Branch, 1989-1990
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ryon, M.G.
1992-01-01
The 1984 Hazardous and Solid Waste Amendments to the Resource Conservation and Recovery Act (RCRA) required assessment of all current and former solid waste management units. Such a RCRA Facility Investigation (RFI) was required of the Y-12 Plant for their Filled Coal Ash Pond on McCoy Branch. Because the disposal of coal ash in the ash pond, McCoy Branch, and Rogers Quarry was not consistent with the Tennessee Water Quality Act, several remediation steps were implemented or planned for McCoy Branch to address disposal problems. The McCoy Branch RFI plan included provisions for biological monitoring of the McCoy Branch watershed.more » The objectives of the biological monitoring were to: (1) document changes in biological quality of McCoy Branch after completion of a pipeline and after termination of all discharges to Rogers Quarry, (2) provide guidance on the need for additional remediation, and (3) evaluate the effectiveness of implemented remedial actions. The data from the biological monitoring program will also determine if the classified uses, as identified by the State of Tennessee, of McCoy Branch are being protected and maintained. This report discusses results from toxicity monitoring of snails fish community assessment, and a Benthic macroinvertebrate community assessment.« less
Hunt, R.J.; Steuer, J.J.
2001-01-01
Why are the effects of urbanization a concern? As the city of Middleton, Wisconsin, and its surroundings continue to develop, the Pheasant Branch watershed (fig.l) is expected to undergo urbanization. For the downstream city of Middleton, urbanization in the watershed can mean increased flood peaks, water volume and pollutant loads. More subtly, it may also reduce water that sustains the ground-water system (called "recharge") and adversely affect downstream ecosystems that depend on ground water such as the Pheasant Branch Springs (hereafter referred to as the Springs). The relation of stormwater runoff and reduced ground-water recharge is complex because the surface-water system is coupled to the underlying ground-water system. In many cases there is movement of water from one system to the other that varies seasonally or daily depending on changing conditions. Therefore, it is difficult to reliably determine the effects of urbanization on stream baseflow and spring flows without rigorous investigation. Moreover, mitigating adverse effects after development has occurred can be expensive and administratively difficult. Overlying these concerns are issues such as stewardship of the resource, the rights of the public, and land owners' rights both of those developing their land and those whose land is affected by this development. With the often- contradictory goals, a scientific basis for assessing effects of urbanization and effectiveness of mitigation measures helps ensure fair and constructive decision-making. The U.S. Geological Survey, in cooperation with the City of Middleton and Wisconsin Department of Natural Resources, completed a study that helps address these issues through modeling of the hydrologic system. This Fact Sheet discusses the results of this work.
ERIC Educational Resources Information Center
Bosl, Rebecca
InfoPlace is a state-of-the-art vocational education program and special library. As part of the Cuyahoga County Library System of Greater Cleveland (Ohio), its resource center is located in the Maple Heights regional library. Although the resource center has one location, the staff of InfoPlace travels to the many branches of the Cuyahoga County…
Scheduling multirobot operations in manufacturing by truncated Petri nets
NASA Astrophysics Data System (ADS)
Chen, Qin; Luh, J. Y.
1995-08-01
Scheduling of operational sequences in manufacturing processes is one of the important problems in automation. Methods of applying Petri nets to model and analyze the problem with constraints on precedence relations, multiple resources allocation, etc. have been available in literature. Searching for an optimum schedule can be implemented by combining the branch-and-bound technique with the execution of the timed Petri net. The process usually produces a large Petri net which is practically not manageable. This disadvantage, however, can be handled by a truncation technique which divides the original large Petri net into several smaller size subnets. The complexity involved in the analysis of each subnet individually is greatly reduced. However, when the locally optimum schedules of the resulting subnets are combined together, it may not yield an overall optimum schedule for the original Petri net. To circumvent this problem, algorithms are developed based on the concepts of Petri net execution and modified branch-and-bound process. The developed technique is applied to a multi-robot task scheduling problem of the manufacturing work cell.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Webb, Erik Karl; Tidwell, Vincent Carroll
2009-10-01
This document outlines ways to more effectively communicate with U.S. Federal decision makers by outlining the structure, authority, and motivations of various Federal groups, how to find the trusted advisors, and how to structure communication. All three branches of Federal governments have decision makers engaged in resolving major policy issues. The Legislative Branch (Congress) negotiates the authority and the resources that can be used by the Executive Branch. The Executive Branch has some latitude in implementation and prioritizing resources. The Judicial Branch resolves disputes. The goal of all decision makers is to choose and implement the option that best fitsmore » the needs and wants of the community. However, understanding the risk of technical, political and/or financial infeasibility and possible unintended consequences is extremely difficult. Primarily, decision makers are supported in their deliberations by trusted advisors who engage in the analysis of options as well as the day-to-day tasks associated with multi-party negotiations. In the best case, the trusted advisors use many sources of information to inform the process including the opinion of experts and if possible predictive analysis from which they can evaluate the projected consequences of their decisions. The paper covers the following: (1) Understanding Executive and Legislative decision makers - What can these decision makers do? (2) Finding the target audience - Who are the internal and external trusted advisors? (3) Packaging the message - How do we parse and integrate information, and how do we use computer simulation or models in policy communication?« less
Yu, Peng; White, Philip J; Li, Chunjian
2015-01-01
Historical domestication and the "Green revolution" have both contributed to the evolution of modern, high-performance crops. Together with increased irrigation and application of chemical fertilizers, these efforts have generated sufficient food for the growing global population. Root architecture, and in particular root branching, plays an important role in the acquisition of water and nutrients, plant performance, and crop yield. Better understanding of root growth and responses to the belowground environment could contribute to overcoming the challenges faced by agriculture today. Manipulating the abilities of crop root systems to explore and exploit the soil environment could enable plants to make the most of soil resources, increase stress tolerance and improve grain yields, while simultaneously reducing environmental degradation. In this article it is noted that the control of root branching, and the responses of root architecture to nitrate availability, differ between root types and between plant species. Since the control of root branching depends upon both plant species and root type, further work is urgently required to determine the appropriate genes to manipulate to improve resource acquisition by specific crops. PMID:26443081
Yu, Peng; White, Philip J; Li, Chunjian
2015-01-01
Historical domestication and the "Green revolution" have both contributed to the evolution of modern, high-performance crops. Together with increased irrigation and application of chemical fertilizers, these efforts have generated sufficient food for the growing global population. Root architecture, and in particular root branching, plays an important role in the acquisition of water and nutrients, plant performance, and crop yield. Better understanding of root growth and responses to the belowground environment could contribute to overcoming the challenges faced by agriculture today. Manipulating the abilities of crop root systems to explore and exploit the soil environment could enable plants to make the most of soil resources, increase stress tolerance and improve grain yields, while simultaneously reducing environmental degradation. In this article it is noted that the control of root branching, and the responses of root architecture to nitrate availability, differ between root types and between plant species. Since the control of root branching depends upon both plant species and root type, further work is urgently required to determine the appropriate genes to manipulate to improve resource acquisition by specific crops.
Administrative Services Division - Alaska Department of Law
Attorney General Opinions Executive Branch Ethics Criminal Justice Alaska Medicaid Fraud Control Anchorage digital communication. Department-wide Information Technology issues, strategic planning, resource
1983-09-01
Profile H-16 North Branch Potomac River H-16 Location H-16 Land Use H-16 Socio -Economic Characteristics H-I8 Archaeological and Historic Resources H- 19...pasture land. Socio - Economic Characteristics In general, the socio -economic characteristics of the North Branch Potomac River Basin are similar to...the formulation of alternative plans and to enable an evaluation of plan effectiveness. Planning objectives may sometimes conflict with each other
Ecological effects of contaminants in McCoy Branch, 1991--1993
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ryon, M.G.
1996-09-01
The 1984 Hazardous and Solid Waste Amendments to the Resource Conservation and Recovery Act (RCRA) required assessment of all current and former solid waste management units. Following guidelines under RCRA and the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), a remedial investigation (RI) was required of the Y-12 Plant for their filled coal ash pond (FCAP) and associated areas on McCoy Branch. The RI process was initiated and assessments were presented. Because the disposal of coal ash in the ash pond, McCoy Branch, and Rogers Quarry was not consistent with the Tennessee Water Quality Act, several remediation steps weremore » implemented between 1986 and 1994 for McCoy Branch to address disposal problems. The required ecological risk assessments of McCoy Branch watershed included provisions for biological monitoring of the watershed. The objectives of the biological monitoring were to (1) document changes in biological quality of McCoy Branch after completion of a pipeline bypassing upper McCoy Branch and further, after termination of all discharges to Rogers Quarry, (2) provide guidance on the need for additional remediation, and (3) evaluate the effectiveness of implemented remedial actions. The data from the biological monitoring program may also determine whether the goals of protection of human health and the environment of McCoy Branch are being accomplished.« less
Urbanization and the problem of restricting the growth of very large cities.
Bialkovskaia, V; Novikov, V
1983-10-01
This article discusses the problem of preventing the excessive growth of very large cities to the detriment of the development of smaller urban settlements in the USSR. The increase in size of the urban population throughout the entire USSR is mainly connected with the increase in the number of city dwellers. In 1960 and 1970 the number of largest cities in the USSR increased, along with a share of the nation's population living in these large cities. The low natural increase in population of very large cities creates a high demand for labor power which must come from the population of other cities. In 1970-1980, Moscow, one of the largest millionaire cities, had the lowest population growth rate of all major USSR cities (113.7%). The growth of Moscow and other very large cities in the last few years has been due to the mechanical increase in population and the increase in area. The analysis of Moscow's pattern of population growth over time focuses on changes in the level of availability of social and everyday services. The prewar period is characterized by a reserve of labor resources, the highest growth in industry and science, but a low overall population dynamic in the city. In the postwar period there was a significant decline in the annual increase of all indicators; this was a period of strong social development of the city. The period between 1966 and 1980 shows a further slowdown in the growth rate of city forming branches by an accelerated development of municipal service branches. The demand for measures to restrict the growth of very large Soviet cities depends on: 1) the reorientation of the development of the economic base, 2) the restructuring of their economy, and 3) the siting of various types of production of goods and services. Developing the specialization of the urban economy consists of planned development of the production of goods and services based on the use of available resources.
Strategy of Irrigation Branch in Russia
NASA Astrophysics Data System (ADS)
Zeyliger, A.; Ermolaeva, O.
2012-04-01
At this moment, at the starting time of the program on restoration of a large irrigation in Russia till 2020, the scientific and technical community of irrigation branch does not have clear vision on how to promote a development of irrigated agriculture and without repeating of mistakes having a place in the past. In many respects absence of a vision is connected to serious backlog of a scientific and technical and informational and technological level of development of domestic irrigation branch from advanced one. Namely such level of development is necessary for the resolving of new problems in new conditions of managing, and also for adequate answers to new challenges from climate and degradation of ground & water resources, as well as a rigorous requirement from an environment. In such important situation for irrigation branch when it is necessary quickly generate a scientific and technical politics for the current decade for maintenance of translation of irrigated agriculture in the Russian Federation on a new highly effective level of development, in our opinion, it is required to carry out open discussion of needs and requirements as well as a research for a adequate solutions. From political point of view a framework organized in FP6 DESIRE 037046 project is an example of good practice that can serve as methodical approach how to organize and develop such processes. From technical point of view a technology of operational management of irrigation at large scale presents a prospective alternative to the current type of management based on planning. From point of view ICT operational management demands creation of a new platform for the professional environment of activity. This platform should allow to perceive processes in real time, at their partial predictability on signals of a straight line and a feedback, within the framework of variability of decision making scenarious, at high resolution and the big ex-awning of sensor controls and the gauges supervising parameters of system, fast proper response to changes in behaviour of controlled system, and all this on a firm support on the creative professional approach of the staff to execution of the professional duties. Development of such professional environment cannot be solved for a short time interval and within the framework of several projects, and will demand the interconnected and purposeful actions directed on extensive information - technological development of administrative and operational segments of irrigation branch. For this purpose it is necessary to develop, create and use the interconnected elements of information - technological developments shown by us in four directions and entitled: 1) Technologies; 2) Infrastructure; 3) Staff; 4) Tools. These four elements will be discussed in a contribution.
Priest, Sheryln; Stamey, Timothy C.; Lawrence, Stephen J.
2002-01-01
In September 2001, the U.S. Geological Survey, in cooperation with the Environmental and Natural Resources Management Office of the U.S. Army Signal Center and Fort Gordon (U.S. Department of the Army), conducted a chemical assessment of surface water, streambed-interstitial water, and bed sediments within the small arms impact area of Fort Gordon Military Installation. The study was conducted in support of the development of an Integrated Natural Resources Management Plan (INRMP) for Fort Gordon, Georgia. An effective INRMP ensures that natural resources conservation measures and U.S. Army activities on the military base are integrated and consistent with Federal requirements to manage military installations on an ecosystem basis. Filtered water samples were collected from five sites along South Prong Creek and three sites along Marcum Branch Creek for chemical analyses of major ions, nutrients, and selected trace elements. On-site measurements of pH, temperature, specific conductance, and dissolved oxygen were made at the eight sites. Filtered water collected showed varying concentrations in both surface- and streambed-interstitial water. Bed-sediment samples collected from South Prong Creek contain elevated levels of arsenic, barium, beryllium, cadmium, chromium, cobalt, copper, iron, lead, manganese, nickel, selenium, vanadium, and total organic carbon relative to previous concentrations (McConnell and others, 2000). Bed-sediment samples collected from Marcum Branch Creek contain elevated levels of beryllium, copper, lead, manganese, mercury, selenium, and total organic carbon relative to previous concentrations (McConnell and others, 2000).
NASA Astrophysics Data System (ADS)
Blythe, Todd L.; Schmidt, John C.
2018-02-01
An estimate of a river's natural flow regime is useful for water resource planning and ecosystem rehabilitation by providing insight into the predisturbance form and function of a river. The natural flow regime of most rivers has been perturbed by development during the 20th century and in some cases, before stream gaging began. The temporal resolution of natural flows estimated using traditional methods is typically not sufficient to evaluate cues that drive native ecosystem function. Additionally, these traditional methods are watershed specific and require large amounts of data to produce accurate results. We present a mass balance method that estimates natural flows at daily time step resolution for the northern branch of the Rio Grande, upstream from the Rio Conchos, that relies only on easily obtained streamflow data. Using an analytical change point method, we identified periods of the measured flow regime during the 20th century for comparison with the estimated natural flows. Our results highlight the significant deviation from natural conditions that occurred during the 20th century. The total annual flow of the northern branch is 95% lower than it would be in the absence of human use. The current 2 year flood has decreased by more than 60%, is shorter in duration, and peaks later in the year. When compared to unregulated flows estimated using traditional mass balance accounting methods, our approach provides similar results.
77 FR 4052 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-26
..., Ph.D., Scientific Review Officer, Resources and Training Review Branch, Division of Extramural....395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397, Cancer Centers Support; 93...
... flu, and have respiratory symptoms without a fever. Digital Resources Prevent Flu! Get a Flu Vaccine and ... by: Office of the Associate Director for Communication, Digital Media Branch, Division of Public Affairs Email Recommend ...
Integrated cloud infrastructure of the LIT JINR, PE "NULITS" and INP's Astana branch
NASA Astrophysics Data System (ADS)
Mazhitova, Yelena; Balashov, Nikita; Baranov, Aleksandr; Kutovskiy, Nikolay; Semenov, Roman
2018-04-01
The article describes the distributed cloud infrastructure deployed on the basis of the resources of the Laboratory of Information Technologies of the Joint Institute for Nuclear Research (LIT JINR) and some JINR Member State organizations. It explains a motivation of that work, an approach it is based on, lists of its participants among which there are private entity "Nazarbayev University Library and IT services" (PE "NULITS") Autonomous Education Organization "Nazarbayev University" (AO NU) and The Institute of Nuclear Physics' (INP's) Astana branch.
77 FR 39714 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-05
..., MD 20814. Contact Person: Gail J. Bryant, MD, Medical Officer, Resources and Training Review Branch..., Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology...
75 FR 21645 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-26
... F. Korczak, PhD, Scientific Review Officer, Resources and Training Review Branch, Division of... Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397, Cancer Centers...
76 FR 78013 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-15
... F. Korczak, Ph.D., Scientific Review Administrator, Resources and Training Review Branch, Division... Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397...
75 FR 21644 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-26
... E Bird, PhD, Chief, Resources and Training Review Branch, Division of Extramural Activities..., Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397, Cancer Centers Support; 93.398...
77 FR 76057 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-26
..., Scientific Review Officer, Resources and Training Review Branch, Division of Extramural Activities, National... Treatment Research; 93.396, Cancer Biology Research; 93.397, Cancer Centers Support; 93.398, Cancer Research...
76 FR 1446 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-10
..., Resources And Training Review Branch, Division of Extramural Activities, National Cancer Institute, NIH..., Cancer Biology Research; 93.397, Cancer Centers Support; 93.398, Cancer Research Manpower; 93.399, Cancer...
76 FR 50234 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-12
...: Jeannette F. Korczak, PhD, Scientific Review Administrator, Resources and Training Review Branch, Division... and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397...
... person. Wash after handling their tissues or laundry. Digital Resources The Flu: A Guide for Parents Do ... by: Office of the Associate Director for Communication, Digital Media Branch, Division of Public Affairs Email Recommend ...
Basic and applied research program. Semiannual report, July-December 1978
DOE Office of Scientific and Technical Information (OSTI.GOV)
Butler, B.L.
1979-12-01
The status of research projects in the Basic and Applied Research Program at SERI is presented for the semiannual period ending December 31, 1978. The five tasks in this program are grouped into Materials Research and Development, Materials Processing and Development, Photoconversion Research, Exploratory Research, and Energy Resource and Assessment and have been carried out by personnel in the Materials, Bio/Chemical Conversion, and Energy Resource and Assessment Branches. Subtask elements in the task areas include coatings and films, polymers, metallurgy and corrosion, optical materials, surfaces and interfaces in materials research and development; photochemistry, photoelectrochemistry, and photobiology in photoconversion; thin glassmore » mirror development, silver degradation of mirrors, hail resistance of thin glass, thin glass manufacturing, cellular glass development, and sorption by desiccants in materials processing and development; and thermoelectric energy conversion, desiccant cooling, photothermal degradation, and amorphous materials in exploratory research. For each task or subtask element, the overview, scope, goals, approach, apparatus and equipment, and supporting subcontracts are presented, as applicable, in addition to the status of the projects in each task or subtask. Listing of publications and reports authored by personnel associated with the Basic and Applied Research Program and prepared or published during 1978 are also included.« less
NASA Astrophysics Data System (ADS)
Pazderin, A. V.; Sof'in, V. V.; Samoylenko, V. O.
2015-11-01
Efforts aimed at improving energy efficiency in all branches of the fuel and energy complex shall be commenced with setting up a high-tech automated system for monitoring and accounting energy resources. Malfunctions and failures in the measurement and information parts of this system may distort commercial measurements of energy resources and lead to financial risks for power supplying organizations. In addition, measurement errors may be connected with intentional distortion of measurements for reducing payment for using energy resources on the consumer's side, which leads to commercial loss of energy resource. The article presents a universal mathematical method for verifying the validity of measurement information in networks for transporting energy resources, such as electricity and heat, petroleum, gas, etc., based on the state estimation theory. The energy resource transportation network is represented by a graph the nodes of which correspond to producers and consumers, and its branches stand for transportation mains (power lines, pipelines, and heat network elements). The main idea of state estimation is connected with obtaining the calculated analogs of energy resources for all available measurements. Unlike "raw" measurements, which contain inaccuracies, the calculated flows of energy resources, called estimates, will fully satisfy the suitability condition for all state equations describing the energy resource transportation network. The state equations written in terms of calculated estimates will be already free from residuals. The difference between a measurement and its calculated analog (estimate) is called in the estimation theory an estimation remainder. The obtained large values of estimation remainders are an indicator of high errors of particular energy resource measurements. By using the presented method it is possible to improve the validity of energy resource measurements, to estimate the transportation network observability, to eliminate the energy resource flows measurement imbalances, and to filter invalid measurements at the data acquisition and processing stage in performing monitoring of an automated energy resource monitoring and accounting system.
A Multiscale Random Field Model for Bayesian Image Segmentation
1994-06-01
ATrN: Natural Resources Branch ATTN G ieCN-C3 D-E Aberden Povig Ground . MD 21005 At Aii-DI (2)AWN IS-TEOMAMr: ATZHI-DtE (2) ATTN: ISH-BECOM Fort...based remotely-sensed data and ground -level data for natural resource inventory and evaluation. Coupling remotely sensed digital data with traditional...ecological ground data could help Army land managers inventory and monitor natural resources. This study used LCTA data sets to D T IC test image
Learning about Gaucher Disease
... Links for Patient Care Education All About the Human Genome Project Fact Sheets Genetic Education Resources for Teachers ... at the Medical Genetics Branch of the National Human Genome Research Institute by Dr. Ellen Sidransky. Dr. Sidransky ...
OVERVIEW: CCL PATHOGENS RESEARCH AT NRMRL
The Microbial Contaminants Control Branch (MCCB), Water Supply and Water Resources Division, National Risk Management Research Laboratory, conducts research on microbiological problems associated with source water quality, treatment processes, distribution and storage of drin...
Genetics Home Reference: short/branched chain acyl-CoA dehydrogenase deficiency
... PDF) Orphanet: 2-methylbutyryl-CoA dehydrogenase deficiency Screening, Technology, and Research in Genetics Patient Support and Advocacy Resources (2 links) Children Living with Inherited Metabolic Diseases (CLIMB) Organic Acidemia ...
77 FR 24969 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-26
.... Contact Person: Sergei Radaev, Ph.D., Scientific Review Officer, Resources and Training Review Branch... Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397...
76 FR 20693 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-13
... Person: Jeannette F Korczak, PhD, Scientific Review Administrator, Resources and Training Review Branch... Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397...
78 FR 18357 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-26
... F.S. Melo, Ph.D., Scientific Review Officer, Resources and Training Review Branch, Division of... and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397...
75 FR 56548 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-16
... Person: Lynn M. Amende, PhD, Scientific Review Officer, Resources and Training Review Branch, Division of....395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397, Cancer Centers Support; 93...
78 FR 20119 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-03
.... Contact Person: Sergei Radaev, Ph.D., Scientific Review Officer, Resources and Training Review Branch... Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer Biology Research; 93.397...
Regulation of branching dynamics by axon-intrinsic asymmetries in Tyrosine Kinase Receptor signaling
Zschätzsch, Marlen; Oliva, Carlos; Langen, Marion; De Geest, Natalie; Özel, Mehmet Neset; Williamson, W Ryan; Lemon, William C; Soldano, Alessia; Munck, Sebastian; Hiesinger, P Robin; Sanchez-Soriano, Natalia; Hassan, Bassem A
2014-01-01
Axonal branching allows a neuron to connect to several targets, increasing neuronal circuit complexity. While axonal branching is well described, the mechanisms that control it remain largely unknown. We find that in the Drosophila CNS branches develop through a process of excessive growth followed by pruning. In vivo high-resolution live imaging of developing brains as well as loss and gain of function experiments show that activation of Epidermal Growth Factor Receptor (EGFR) is necessary for branch dynamics and the final branching pattern. Live imaging also reveals that intrinsic asymmetry in EGFR localization regulates the balance between dynamic and static filopodia. Elimination of signaling asymmetry by either loss or gain of EGFR function results in reduced dynamics leading to excessive branch formation. In summary, we propose that the dynamic process of axon branch development is mediated by differential local distribution of signaling receptors. DOI: http://dx.doi.org/10.7554/eLife.01699.001 PMID:24755286
CZM from the state perspective: the New Jersey experience
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kinsey, D.N.
1985-01-01
In the late 1800s and early 1900s, New Jersey sold extensive tide-flowed lands at bargain prices to railroad and land development companies to promote seashore and waterfront development. Beginning in 1869, the legislature entrusted the executive branch with the responsibility of selling tide-flowing lands. In the early 1900s, the state began regulation of construction along tidal waterfronts. Beginning in the 1940s, state government undertook various shore protection projects, funding the construction of groins, jetties, dredging activities, and beach nourishment projects in the Jersey Shore. Enactment in 1970 of the Wetlands Act clearly signaled recognition of the need for a strongmore » state role in the management of fragile coastal resources. Finally the Coastal Area Facility Review Act (CAFRA) was enacted in 1973, the year after passage of the federal Coastal Zone Management Act of 1972 (CZMA). CZMA provided the State of New Jersey and other coastal states and territories with new incentives and requirements for managing coastal resources. The pressures faced by New Jersey's coast of offshore oil and gas exploration, recreation, fisheries development, casino gambling, and many other activities, along with the opportunities provided by the CZMA, have further intensified and concentrated New Jersey's efforts to manage its coastal resources. 108 references.« less
Metal recovery by bioleaching of sulfidic mining wastes — Application to a European case study
NASA Astrophysics Data System (ADS)
Guézennec, A. G.; Jacob, J.; Joulian, C.; Dupraz, S.; Menard, Y.; d'Hugues, P.
The non-energy extractive industry (NEEI) of the EU-25 generated a direct turnover of about €40 billion, and provided employment to about 250000 people in 16629 companies in 2004. The use of primary raw materials in the production of other branches of EU industry means they have a central role in guaranteeing industrial and economic sustainability. Nevertheless current demand exceeds production, and so the EU is heavily dependent on minerals and metals imports. In this context of securing access to metals, turning mining wastes into new resources of currently unexploited valuable metals is an important challenge. The mining wastes can contain base and precious metals, but also metalloids and rare earth elements that are nowadays considered as highly critical for the industrial development of the European Union. Nevertheless, the development of alternative routes to conventional processing is still required in order to decrease the cost associated to the treatment of these unconventional resources which are more complex in composition and with lower grades.
[Services portfolio of a department of endocrinology and clinical nutrition].
Vicente Delgado, Almudena; Gómez Enterría, Pilar; Tinahones Madueño, Francisco
2011-03-01
Endocrinology and Clinical Nutrition are branches of Medicine that deal with the study of physiology of body glands and hormones and their disorders, intermediate metabolism of nutrients, enteral and parenteral nutrition, promotion of health by prevention of diet-related diseases, and appropriate use of the diagnostic, therapeutic, and preventive tools related to these disciplines. Development of Endocrinology and Clinical Nutrition support services requires accurate definition and management of a number of complex resources, both human and material, as well as adequate planning of the care provided. It is therefore essential to know the services portfolio of an ideal Department of Endocrinology and Clinical Nutrition because this is a useful, valid and necessary tool to optimize the available resources, to increase efficiency, and to improve the quality of care. Copyright © 2010 SEEN. Published by Elsevier Espana. All rights reserved.
75 FR 46943 - Agency Information Collection Activities: Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-04
...-capturing process. SAMHSA will place Web site registration information into a Knowledge Management database... September 3, 2010 to: SAMHSA Desk Officer, Human Resources and Housing Branch, Office of Management and...
Crofts, Naoko; Nakamura, Yasunori; Fujita, Naoko
2017-09-01
Starch accounts for the majority of edible carbohydrate resources generated through photosynthesis. Amylopectin is the major component of starch and is one of highest-molecular-weight biopolymers. Rapid and systematic synthesis of frequently branched hydro-insoluble amylopectin and efficient accumulation into amyloplasts of cereal endosperm is crucial. The functions of multiple starch biosynthetic enzymes, including elongation, branching, and debranching enzymes, must be temporally and spatially coordinated. Accordingly, direct evidence of protein-protein interactions of starch biosynthetic enzymes were first discovered in developing wheat endosperm in 2004, and they have since been shown in the developing seeds of other cereals. This review article describes structural characteristics of starches as well as similarities and differences in protein complex formation among different plant species and among mutant plants that are deficient in specific starch biosynthetic enzymes. In addition, evidence for protein complexes that are involved in the initiation stages of starch biosynthesis is summarized. Finally, we discuss the significance of protein complexes and describe new methods that may elucidate the mechanisms and roles of starch biosynthetic enzyme complexes. Copyright © 2017 Elsevier B.V. All rights reserved.
Existing branches correlatively inhibit further branching in Trifolium repens: possible mechanisms
Thomas, R. G.; Hay, M. J. M.
2011-01-01
In Trifolium repens removal of any number of existing branches distal to a nodal root stimulates development of axillary buds further along the stem such that the complement of branches distal to a nodal root remains constant. This study aimed to assess possible mechanisms by which existing branches correlatively inhibit the outgrowth of axillary buds distal to them. Treatments were applied to basal branches to evaluate the roles of three postulated inhibitory mechanisms: (I) the transport of a phloem-mobile inhibitory feedback signal from branches into the main stem; (II) the polar flow of auxin from branches into the main stem acting to limit further branch development; or (III) the basal branches functioning as sinks for a net root-derived stimulatory signal (NRS). Results showed that transport of auxin, or of a non-auxin phloem-mobile signal, from basal branches did not influence regulation of correlative inhibition and were consistent with the possibility that the intra-plant distribution of NRS could be involved in the correlative inhibition of distal buds by basal branches. This study supports existing evidence that regulation of branching in T. repens is dominated by a root-derived stimulatory signal, initially distributed via the xylem, the characterization of which will progress the generic understanding of branching regulation. PMID:21071681
Simulation of the evolution of root water foraging strategies in dry and shallow soils.
Renton, Michael; Poot, Pieter
2014-09-01
The dynamic structural development of plants can be seen as a strategy for exploiting the limited resources available within their environment, and we would expect that evolution would lead to efficient strategies that reduce costs while maximizing resource acquisition. In particular, perennial species endemic to habitats with shallow soils in seasonally dry environments have been shown to have a specialized root system morphology that may enhance access to water resources in the underlying rock. This study aimed to explore these hypotheses by applying evolutionary algorithms to a functional-structural root growth model. A simulation model of a plant's root system was developed, which represents the dynamics of water uptake and structural growth. The model is simple enough for evolutionary optimization to be computationally feasible, yet flexible enough to allow a range of structural development strategies to be explored. The model was combined with an evolutionary algorithm in order to investigate a case study habitat with a highly heterogeneous distribution of resources, both spatially and temporally--the situation of perennial plants occurring on shallow soils in seasonally dry environments. Evolution was simulated under two contrasting fitness criteria: (1) the ability to find wet cracks in underlying rock, and (2) maximizing above-ground biomass. The novel approach successfully resulted in the evolution of more efficient structural development strategies for both fitness criteria. Different rooting strategies evolved when different criteria were applied, and each evolved strategy made ecological sense in terms of the corresponding fitness criterion. Evolution selected for root system morphologies which matched those of real species from corresponding habitats. Specialized root morphology with deeper rather than shallower lateral branching enhances access to water resources in underlying rock. More generally, the approach provides insights into both evolutionary processes and ecological costs and benefits of different plant growth strategies.
ERIC Educational Resources Information Center
Chee, Chiu Mei; Butt, Muhammad Mohsin; Wilkins, Stephen; Ong, Fon Sim
2016-01-01
Over the last decade, international branch campuses have been established by universities from developing countries as well as developed countries. Little research has been conducted into students' perceptions of branch campuses from different countries, or how universities from different countries compete in the increasingly competitive market. A…
Composite Overview and Composite Aerocover Overview
NASA Technical Reports Server (NTRS)
Caraccio, Anne; Tate, LaNetra; Dokos, Adam; Taylor, Brian; Brown, Chad
2014-01-01
Materials Science Division within the Engineering Directorate tasked by the Ares Launch Vehicle Division (LX-V) and the Fluids Testing and Technology Development Branch (NE-F6) to design, fabricate and test an aerodynamic composite shield for potential Heavy Lift Launch Vehicle infusion and a composite strut that will serve as a pathfinder in evaluating calorimeter data for the CRYOSTAT (cryogenic on orbit storage and transfer) Project. ATP project is to carry the design and development of the aerodynamic composite cover or "bracket" from cradle to grave including materials research, purchasing, design, fabrication, testing, analysis and presentation of the final product. Effort consisted of support from the Materials Testing & Corrosion Control Branch (NE-L2) for mechanical testing, the Prototype Development Branch (NE-L3) for CAD drawing, design/analysis, and fabrication, Materials & Processes Engineering Branch (NE-L4) for project management and materials selection; the Applied Physics Branch (NE-LS) for NDE/NDI support; and the Chemical Analysis Branch (NE-L6) for developmental systems evaluation. Funded by the Ares Launch Vehicle Division and the Fluids Testing and Technology Development Branch will provide ODC
Follansbee, Robert
1944-01-01
The 11-year period from July 1, 1928, to June 30, 1939, was one of violent contrasts , both naturall and man-made; great floods and severe droughts occurred and great industrial activity 'W'as· succeeded by deep and persistent depression which droughts made even more devastating. It spans the· time from the first year of 50-50 cooperation with the States, to the last year that Nathan C. Grover was Chief of the Branch.
The evolution of resource adaptation: how generalist and specialist consumers evolve.
Ma, Junling; Levin, Simon A
2006-07-01
Why and how specialist and generalist strategies evolve are important questions in evolutionary ecology. In this paper, with the method of adaptive dynamics and evolutionary branching, we identify conditions that select for specialist and generalist strategies. Generally, generalist strategies evolve if there is a switching benefit; specialists evolve if there is a switching cost. If the switching cost is large, specialists always evolve. If the switching cost is small, even though the consumer will first evolve toward a generalist strategy, it will eventually branch into two specialists.
NASA Technical Reports Server (NTRS)
Fisher, A.; Staugaitis, C. L.
1974-01-01
The capabilities of the Materials Engineering Branch (MEB) of the Goddard Space Flight Center, Greenbelt, Maryland, are surveyed. The specific functions of spacecraft materials review, materials processing and information dissemination, and laboratory support, are outlined in the Activity Report. Further detail is provided by case histories of laboratory satellite support and equipment. Project support statistics are shown, and complete listings of MEB publications, patents, and tech briefs are included. MEB staff, and their respective discipline areas and spacecraft liaison associations, are listed.
Developmental Programming of Branching Morphogenesis in the Kidney
Schneider, Laura; Al-Awqati, Qais
2015-01-01
The kidney developmental program encodes the intricate branching and organization of approximately 1 million functional units (nephrons). Branching regulation is poorly understood, as is the source of a 10-fold variation in nephron number. Notably, low nephron count increases the risk for developing hypertension and renal failure. To better understand the source of this variation, we analyzed the complete gestational trajectory of mouse kidney development. We constructed a computerized architectural map of the branching process throughout fetal life and found that organogenesis is composed of two distinct developmental phases, each with stage-specific rate and morphologic parameters. The early phase is characterized by a rapid acceleration in branching rate and by branching divisions that repeat with relatively reproducible morphology. The latter phase, however, is notable for a significantly decreased yet constant branching rate and the presence of nonstereotyped branching events that generate progressive variability in tree morphology until birth. Our map identifies and quantitates the contribution of four developmental mechanisms that guide organogenesis: growth, patterning, branching rate, and nephron induction. When applied to organs that developed under conditions of malnutrition or in the setting of growth factor mutation, our normative map provided an essential link between kidney architecture and the fundamental morphogenetic mechanisms that guide development. This morphogenetic map is expected to find widespread applications and help identify modifiable targets to prevent developmental programming of common diseases. PMID:25644110
Developmental Programming of Branching Morphogenesis in the Kidney.
Sampogna, Rosemary V; Schneider, Laura; Al-Awqati, Qais
2015-10-01
The kidney developmental program encodes the intricate branching and organization of approximately 1 million functional units (nephrons). Branching regulation is poorly understood, as is the source of a 10-fold variation in nephron number. Notably, low nephron count increases the risk for developing hypertension and renal failure. To better understand the source of this variation, we analyzed the complete gestational trajectory of mouse kidney development. We constructed a computerized architectural map of the branching process throughout fetal life and found that organogenesis is composed of two distinct developmental phases, each with stage-specific rate and morphologic parameters. The early phase is characterized by a rapid acceleration in branching rate and by branching divisions that repeat with relatively reproducible morphology. The latter phase, however, is notable for a significantly decreased yet constant branching rate and the presence of nonstereotyped branching events that generate progressive variability in tree morphology until birth. Our map identifies and quantitates the contribution of four developmental mechanisms that guide organogenesis: growth, patterning, branching rate, and nephron induction. When applied to organs that developed under conditions of malnutrition or in the setting of growth factor mutation, our normative map provided an essential link between kidney architecture and the fundamental morphogenetic mechanisms that guide development. This morphogenetic map is expected to find widespread applications and help identify modifiable targets to prevent developmental programming of common diseases. Copyright © 2015 by the American Society of Nephrology.
Costs Associated with Using the ASA24® Dietary Assessment Tool
As part of its mission to advance measures and methods for monitoring cancer-related behaviors and other risk factors, the Risk Factor Assessment Branch provides tools and resources to the extramural research community.
Nicole Lautze
2015-01-01
Groundwater flow model for the island of Oahu. Data is from the following sources: Rotzoll, K., A.I. El-Kadi. 2007. Numerical Ground-Water Flow Simulation for Red Hill Fuel Storage Facilities, NAVFAC Pacific, Oahu, Hawaii - Prepared TEC, Inc. Water Resources Research Center, University of Hawaii, Honolulu.; Whittier, R.B., K. Rotzoll, S. Dhal, A.I. El-Kadi, C. Ray, G. Chen, and D. Chang. 2004. Hawaii Source Water Assessment Program Report – Volume VII – Island of Oahu Source Water Assessment Program Report. Prepared for the Hawaii Department of Health, Safe Drinking Water Branch. University of Hawaii, Water Resources Research Center. Updated 2008.; and Whittier, R. and A.I. El-Kadi. 2009. Human and Environmental Risk Ranking of Onsite Sewage Disposal Systems – Final. Prepared by the University of Hawaii, Dept. of Geology and Geophysics for the State of Hawaii Dept. of Health, Safe Drinking Water Branch. December 2009.
Dong, Tingfa; Li, Junyu; Zhang, Yuanbin; Korpelainen, Helena; Niinemets, Ülo; Li, Chunyang
2015-06-01
The degree to which branches are autonomous in their acclimation responses to alteration in light environment is still poorly understood. We investigated the effects of shading of the sapling crown of Cunninghamia lanceolata (Lamb.) Hook on the whole-tree and mid-crown branch growth and current-year foliage structure and physiology. Four treatments providing 0, 50, 75 and 90% shading compared with full daylight (denoted as Treatment(0), Treatment(50%), Treatment(75%) and Treatment(90%), and Shaded(0), Shaded(50%), Shaded(75%) and Shaded(90%) for the shaded branches and Sunlit(0), Sunlit(50%), Sunlit(75%) and Sunlit(90%) for the opposite sunlit branches under natural light conditions, respectively), were applied over two consecutive growing seasons. Shading treatments decreased the growth of basal stem diameter, leaf dry mass per unit leaf area, stomatal conductance, transpiration rate, the ratio of water-soluble to structural leaf nitrogen content, photosynthetic nitrogen-use efficiency and instantaneous and long-term (estimated from carbon isotope composition) water-use efficiency in shaded branches. Differences between shaded and sunlit branches increased with increasing severity and duration of shading. A non-autonomous, partly compensatory behavior of non-shaded branches was observed for most traits, thus reflecting the dependence between the traits of sunlit branches and the severity of shading of the opposite crown half. The results collectively indicated that tree growth and branch and leaf acclimation responses of C. lanceolata are not only affected by the local light environment, but also by relative within-crown light conditions. We argue that such a non-autonomous branch response to changes in light conditions can improve whole-tree resource optimization. These results contribute to better understanding of tree growth and utilization of water and nitrogen under heterogeneous light conditions within tree canopies. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Flood Control Wild Rice River - South Branch and Felton Ditch, Minnesota.
1974-09-01
good water quality in the proposed project area except that measure- ments for certain parameters, notably heavy metals , exceed the standards for...Topography 5 Soils 6 Climate 8 Groundwater 10 Vegetation 10 Stream Resources 13 Animal Resources 15 Water Quality 16 Regional Economics 17 Watershed... sources . The advisability of low-growing shrubs and trees along the channel would also be considered. Plate 2 illustrates several possible
Role of TCP Gene BRANCHED1 in the Control of Shoot Branching in Arabidopsis.
Poza-Carrión, César; Aguilar-Martínez, José Antonio; Cubas, Pilar
2007-11-01
Branching patterns are major determinants of plant architecture. They depend both on leaf phillotaxy (branch primordia are formed in the axils of leaves) and on the decision of buds to grow out to give a branch or to remain dormant. In Arabidopsis, several genes involved in the long-distance signalling of the control of branch outgrowth have been identified. However, the genes acting inside the buds to cause growth arrest remained unknown until now. In the February issue of Plant Cell we have described the function of BRANCHED1 (BRC1), an Arabidopsis gene coding for a plant-specific transcription factor of the TCP family that is expressed in the buds and prevents their development. Loss of BRC1 function leads to accelerated AM initiation, precocious progression of bud development and excess of shoot branching. BRC1 transcription is affected by endogenous and environmental signals controlling branching and we have shown that BRC1 function mediates the response to these stimuli. Therefore we have proposed that BRC1 function represents the point at which signals controlling branching are integrated within axillary buds.
Tenure Track Investigator | Center for Cancer Research
This position, which is supported with stable financial resources, is the equivalent of Assistant Professor/Associate Professor in an academic department. The Thoracic and Gastrointestinal Oncology Branch (TGIB) is looking for a candidate who will complement our current group of principal investigators focused on thoracic and gastrointestinal (GI) cancers. The candidate is expected to develop a translational research program focused on GI cancers. As such, the candidate will conduct both laboratory-based investigations, as well as develop a clinical program related to work being conducted in his or her laboratory. We encourage outstanding physician scientists investigating any area of GI research to apply. Areas of interest include, but are not limited to, hepatobiliary and colon rectal cancer, and development of novel therapeutics. Candidates may be eligible to join the NCI Liver Cancer Program.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-21
...-2010-0150,'' Regulatory Development Section, Air Planning Branch, Air, Pesticides and Toxics Management... Planning Branch, Air, Pesticides and Toxics Management Division, U.S. Environmental Protection Agency... at the Regulatory Development Section, Air Planning Branch, Air, Pesticides and Toxics Management...
Osada, Noriyuki
2006-01-01
Based on an allometric reconstruction, the structure and biomass-allocation patterns of branches and current-year shoots were investigated in branches of various heights in the pioneer tree Rhus trichocarpa, to evaluate how crown development is achieved and limited in association with height. Path analysis was conducted to explore the effects of light availability, basal height and size of individual branches on branch structure and growth. Branch angle was affected by basal height, whereas branch mass was influenced primarily by light availability. This result suggests that branch structure is strongly constrained by basal height, and that trees mediate such constraints under different light environments. Previous-year leaf area and light availability showed positive effects on current-year stem mass. In contrast, branch basal height and mass negatively affected current-year stem mass. Moreover, the length of stems of a given diameter decreased with increasing branch height. Therefore the cost of biomass investment for a unit growth in length is greater for branches of larger size and at upper positions. Vertical growth rate in length decreased with increasing height. Height-dependent changes in stem allometry and angle influenced the reduction in vertical growth rate to a similar degree.
Structural development of redwood branches and its effects on wood growth.
Kramer, Russell D; Sillett, Stephen C; Carroll, Allyson L
2014-03-01
Redwood branches provide all the carbohydrates for the most carbon-heavy forests on Earth, and recent whole-tree measurements have quantified trunk growth rates associated with complete branch inventories. Providing all of a tree's photosynthetic capacity, branches represent an increasing proportion of total aboveground wood production as trees enlarge. To examine branch development and its effects on wood volume growth, we dissected 31 branches from eight Sequoia sempervirens (D. Don) Endl. and seven Sequoiadendron giganteum Lindl. trees. The cambium-area-to-leaf-area ratio was maintained with size and age but increased with light availability, whereas the heartwood-deposition-area-to-leaf-area ratio increased with size and age but was insensitive to light availability. The proportion of foliage mass arrayed in <1-cm-diameter epicormic shoots increased with decreasing light and was higher in Sequoia (20-60%) than in Sequoiadendron (3-16%). Well-illuminated branches concentrated leaves higher and distally, while shaded branches distributed leaves lower and proximally. In similar light environments, older branches distributed leaves lower and more proximally than younger branches. Branch size, light, species, heartwood area, a heartwood-area-species interaction, and ovulate cone mass predicted 87.5% of the variability in wood volume growth of branches. After accounting for the positive effects of size and light, wood volume growth declined with heartwood area and age. The effect of age was trivial compared to the effect of heartwood area, suggesting that heartwood expansion caused the age-related decline in wood volume growth. Additionally, Sequoiadendron branches of similar size and light environment with more ovulate cones produced less wood, even though these cones were long-lived and photosynthetic, reflecting the energetic cost of seed production. These results contributed to a conceptual model of branch development in which light availability, injury, heartwood content, gravity, and time interact to produce the high degree of branch structural variation evident within redwood crowns.
Asymmetric Branching in Biological Resource Distribution Networks
NASA Astrophysics Data System (ADS)
Brummer, Alexander Byers
There is a remarkable relationship between an organism's metabolic rate (resting power consumption) and the organism's mass. It may be a universal law of nature that an organism's resting metabolic rate is proportional to its mass to the power of 3/4. This relationship, known as Kleiber's Law, appears to be valid for both plants and animals. This law is important because it implies that larger organisms are more efficient than smaller organisms, and knowledge regarding metabolic rates are essential to a multitude of other fields in ecology and biology. This includes modeling the interactions of many species across multiple trophic levels, distributions of species abundances across large spatial landscapes, and even medical diagnostics for respiratory and cardiovascular pathologies. Previous models of vascular networks that seek to identify the origin of metabolic scaling have all been based on the unrealistic assumption of perfectly symmetric branching. In this dissertation I will present a theory of asymmetric branching in self-similar vascular networks (published by Brummer et al. in [9]). The theory shows that there can exist a suite of vascular forms that result in the often observed 3/4 metabolic scaling exponent of Kleiber's Law. Furthermore, the theory makes predictions regarding major morphological features related to vascular branching patterns and their relationships to metabolic scaling. These predictions are suggestive of evolutionary convergence in vascular branching. To test these predictions, I will present an analysis of real mammalian and plant vascular data that shows: (i) broad patterns in vascular networks across entire animal kingdoms and (ii) within these patterns, plant and mammalian vascular networks can be uniquely distinguished from one another (publication in preparation by Brummer et al.). I will also present results from a computational study in support of point (i). Namely, that asymmetric branching may be the optimal strategy to balance the simultaneous demands of maximizing the number of nutrient exchange sites (capillaries or leaves) versus hydraulic resistance to resource transport (publication in preparation by Brummer et al.). Finally, I report on improved methods of estimating whole organism metabolism based solely on measurements of vasculature.
141. INTERIOR, SEVENTH FLOOR, WING 7100 WEST, ROOM 7138, DOUBLE ...
141. INTERIOR, SEVENTH FLOOR, WING 7100 WEST, ROOM 7138, DOUBLE DOOR TO THE LAW BRANCH OF THE NATIONAL LIBRARY OF NATURAL RESOURCES - U.S. Department of the Interior, Eighteenth & C Streets Northwest, Washington, District of Columbia, DC
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-27
... Section, Air Planning Branch, Air, Pesticides and Toxics Management Division, U.S. Environmental...: Lynorae Benjamin, Chief, Regulatory Development Section, Air Planning Branch, Air, Pesticides and Toxics... Bradley, Regulatory Development Section, Air Planning Branch, Air, Pesticides and Toxics Management...
ERIC Educational Resources Information Center
National Inst. of Child Health and Human Development (NIH), Bethesda, MD. Center for Research for Mothers and Children.
This report describes current research activities and future plans of the Pediatric, Adolescent, and Maternal AIDS (PAMA) Branch of the National Institute of Child Health and Human Development's Center for Research for Mothers and Children. The mission statement of the Branch notes that PAMA develops, implements, and directs a wide range of…
ERIC Educational Resources Information Center
Hill, Christopher; Thabet, Rawy Abdelrahman
2018-01-01
Purpose: International branch campuses (IBCs) are complex entities and while much has been written about their expansion and development, the literature is largely from an external perspective. There have been few longitudinal studies examining the development of an IBC over time. The purpose of this paper is to review the development of one IBC…
Predicting the cover-up of dead branches using a simple single regressor equation
Christopher M. Oswalt; Wayne K. Clatterbuck; E.C. Burkhardt
2007-01-01
Information on the effects of branch diameter on branch occlusion is necessary for building models capable of forecasting the effect of management decisions on tree or log grade. We investigated the relationship between branch size and subsequent branch occlusion through diameter growth with special attention toward the development of a simple single regressor equation...
Phototropic growth in a reef flat acroporid branching coral species.
Kaniewska, Paulina; Campbell, Paul R; Fine, Maoz; Hoegh-Guldberg, Ove
2009-03-01
Many terrestrial plants form complex morphological structures and will alter these growth patterns in response to light direction. Similarly reef building corals have high morphological variation across coral families, with many species also displaying phenotypic plasticity across environmental gradients. In particular, the colony geometry in branching corals is altered by the frequency, location and direction of branch initiation and growth. This study demonstrates that for the branching species Acropora pulchra, light plays a key role in axial polyp differentiation and therefore axial corallite development--the basis for new branch formation. A. pulchra branches exhibited a directional growth response, with axial corallites only developing when light was available, and towards the incident light. Field experimentation revealed that there was a light intensity threshold of 45 micromol m(-2) s(-1), below which axial corallites would not develop and this response was blue light (408-508 nm) dependent. There was a twofold increase in axial corallite growth above this light intensity threshold and a fourfold increase in axial corallite growth under the blue light treatment. These features of coral branch growth are highly reminiscent of the initiation of phototropic branch growth in terrestrial plants, which is directed by the blue light component of sunlight.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-14
... Planning Branch, Air, Pesticides and Toxics Management Division, U.S. Environmental Protection Agency..., Regulatory Development Section, Air Planning Branch, Air, Pesticides and Toxics Management Division, U.S... Development Section, Air Planning Branch, Air, Pesticides and Toxics Management Division, U.S. Environmental...
Clune, John W.; Denver, Judith M.
2012-01-01
Nitrate is a common contaminant in groundwater and surface water throughout the Nation, and water-resource managers need more detailed small-scale watershed research to guide conservation efforts aimed at improving water quality. Concentrations of nitrate in Bucks Branch are among the highest in the state of Delaware and a scientific investigation was performed to provide water-quality information to assist with the management of agriculture and water resources. A combination of major-ion chemistry, nitrogen isotopic composition and age-dating techniques was used to estimate the residence time and provide a chemical and isotopic analysis of nitrate in the groundwater in the surficial aquifer of the Bucks Branch watershed in Sussex County, Delaware. The land use was more than 90 percent agricultural and most nitrogen inputs were from manure and fertilizer. The apparent median age of sampled groundwater is 18 years and the estimated residence time of groundwater contributing to the streamflow for the entire Bucks Branch watershed at the outlet is approximately 19 years. Concentrations of nitrate exceeded the U.S. Environmental Protection Agency drinking-water standard of 10 milligrams per liter (as nitrogen) in 60 percent of groundwater samples and 42 percent of surface-water samples. The overall geochemistry in the Bucks Branch watershed indicates that agriculture is the predominant source of nitrate contamination and the observed patterns in major-ion chemistry are similar to those observed in other studies on the Mid-Atlantic Coastal Plain. The pattern of enrichment in nitrogen and oxygen isotopes (δ15N and δ18O) of nitrate in groundwater and surface water indicates there is some loss of nitrate through denitrification, but this process is not sufficient to remove all of the nitrate from groundwater discharging to streams, and concentrations of nitrate in streams remain elevated.
2015-12-01
Occupational Injuries COPS Community Oriented Policing Services CRM Crew Resource Management DA Department of the Army FEMA Federal Emergency...establishes composite risk management ( CRM ), also known as crew resource management, “as the Army’s principal risk reduction methodology and assures...regulatory and statutory compliance.”106 CRM , also utilized by other branches within the military and by the aviation industry, is intended “to minimize
1985-07-12
Falls; Joseph Minshaw, Little Falls; Anne Rebischke and Cheryl Seelen, Carnegie Library, Little Falls; Darwin Carlson, Charlene Starin, and Veryl E...Fort Snelling History Center, St. Paul. Cheryl Seelen, Carnegie Library, Little Falls. Jan Warner, Morrison County Historical Society, Weyerhaeuser...Enclosure Wayne A. Knott Chief, Environmental Resources Branch Planning Division o" %~*-:\\\\~% v~~ ~* ** . **:- ~** , -108- Ki ST. PAUL DISTRICT
Water resources of the Marquette Iron Range area, Michigan
Wiitala, Sulo Werner; Newport, Thomas Gwyn; Skinner, Earl L.
1967-01-01
Large quantities of water are needed in the beneficiation and pelletizing processes by which the ore mined from low-grade iron-formations is upgraded into an excellent raw material for the iron and steel industry. Extensive reserves of low-grade iron-formation available for development herald an intensification of the demands upon the area's water supplies. This study was designed to provide water facts for public and private agencies in planning orderly development and in guiding the management of the water resources to meet existing and new requirements. Inland lakes and streams are the best potential sources of water for immediate development. The natural flow available for 90 percent of the time in the Middle and East Branches of the Escanaba River, the Carp River, and the Michigamme River is about 190 cubic feet per second. Potential storage sites are identified, and their complete development could increase the available supply from the above streams to about 450 cubic feet per second. Outwash deposits are the best potential sources of ground water. Large supplies could be developed from extensive outwash deposits in the eastern part of the area adjacent to Goose Lake Outlet and the East Branch Escanaba River. Other areas of outwash occur in the vicinity of Humboldt, West Branch Creek, and along the stream valleys. Streamflow data were used to make rough approximations of the ground-water potential in some areas. In general, however, the available data were not sufficient to permit quantitative evaluation of the potential ground-water supplies. Chemical quality of the surface and ground waters of the area is generally acceptable for most uses. Suspended sediment in the form of mineral tailings in effluents from ore-processing plants is a potential problem. Existing plants use settling basins to effectively remove most of the suspended material. Available records indicate that suspended-sediment concentrations and loads in the receiving waters have not been significantly increased by these operations. Present water use is about 60 cubic feet per second in the area. Thus, available water supplies are believed to be adequate for existing and foreseeable new uses. Water management, rather than water availability, is of prime consideration in this area. Time distribution of available water supplies, distribution of water to points of use, effect of surface-water development upon ground water and vice versa, and possible conflicts with competing uses are some of the management problems that are discussed. The presence of many inland lakes, favorable storage sites on streams, and several promising acquifers provide flexibility in possible water-management operations. A discussion of the interrelationships between surface and ground water and a ground-water budget are presented to render a better understanding of the hydrologic system with which water management will be concerned.
78 FR 19275 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-29
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel Tumor Immunology...., Chief Resources and Training Review Branch, Division of Extramural Activities, National Cancer Institute...
76 FR 57063 - National Cancer Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-15
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... personal privacy. Name of Committee: National Cancer Institute Initial Review Group, Subcommittee F..., Resources and Training Review Branch, Division of Extramural Activities, National Cancer Institute, NIH...
Outsourcing the Portal: Another Branch in the Decision Tree.
ERIC Educational Resources Information Center
McMahon, Tim
2000-01-01
Discussion of the management of information resources in organizations focuses on the use of portal technologies to update intranet capabilities. Considers application outsourcing decisions, reviews benefits (including reducing costs) as well as concerns, and describes application service providers (ASPs). (LRW)
ANIMAL-HABITAT ASSOCIATIONS IN PACIFIC NORTHWEST ESTUARIES
The mission of the Pacific Coastal Ecology Branch (EPA, Newport, OR) is to determine the effects of habitat alteration by stressors on ecological resources in Pacific Northwest (PNW) estuaries. Research being conducted in support of this mission includes identifying critical hab...
2010-01-01
The Fort Collins Science Center's Policy Analysis and Science Assistance (PASA) Branch is a team of approximately 22 scientists, technicians, and graduate student researchers. PASA provides unique capabilities in the U.S. Geological Survey by leading projects that integrate social, behavioral, economic, and biological analyses in the context of human-natural resource interactions. Resource planners, managers, and policymakers in the U.S. Departments of the Interior (DOI) and Agriculture (USDA), State and local agencies, as well as international agencies use information from PASA studies to make informed natural resource management and policy decisions. PASA scientists' primary functions are to conduct both theoretical and applied social science research, provide technical assistance, and offer training to advance performance in policy relevant research areas. Management and research issues associated with human-resource interactions typically occur in a unique context, involve difficult to access populations, require knowledge of both natural/biological science in addition to social science, and require the skill to integrate multiple science disciplines. In response to these difficult contexts, PASA researchers apply traditional and state-of-the-art social science methods drawing from the fields of sociology, demography, economics, political science, communications, social-psychology, and applied industrial organization psychology. Social science methods work in concert with our rangeland/agricultural management, wildlife, ecology, and biology capabilities. The goal of PASA's research is to enhance natural resource management, agency functions, policies, and decision-making. Our research is organized into four broad areas of study.
Combat Resource Management (11bm) Applied Research Project (ARP)
2009-12-01
C o m b a t R e s o u r c e M a n a g e m e n t (11bm) Appl ied Research Pro ject ( A R P ) : F i n a l re p o rt A. Benaskeur DRDC Valcartier...instance, during the plan execution, one should follow one branch or another depending on the result of an engagement to some threat T (i). If this...engagement has succeeded, then the plan continues by following a branch where it does not consider the target T (i) anymore. If the engagement has failed
Home Away from Home?: A Case Study of Student Transitions to an International Branch Campus
ERIC Educational Resources Information Center
Cicchetti, Kaitlin Oyler
2017-01-01
This study explored the transition experience of home-campus students attending an international branch campus. The studied was informed by a diverse range of literature, including the internationalization of higher education and student affairs, development of international branch campuses, students in transition, the development of student…
Friebele, Charlotte D.
1975-01-01
Water-resources investigations in Texas consist of the collection of basic records through the hydrologic-data network, interpretive studies, and research projects. An office was established in Austin, Texas, in 1915 for surface-water studies, for ground-water studies in 1929, and water-quality studies in 1937. Previous investigations of the water resources of Texas were carried out by personnel of the U.S. Geological Survey from the Washington headquarters. The basic-data records and the results of investigations are published by the Geological Survey or by cooperating agencies.Geologic investigations were made by personnel from Washington and Denver as early as 1887. The Geophysics Branch of the Geologic Division maintained an office in Austin from 1954 to 1974. Results of these investigations were published by the Geological Survey.This bibliography lists alphabetically by author all reports prepared as a result of Geological Survey investigations in Texas, many of which were carried out in cooperation with the Texas Water Development Board and its predecessor agencies, river authorities, other State and local agencies, and other Federal agencies.
NASA Astrophysics Data System (ADS)
Biały, Witold
2016-12-01
Smart specialisations, a new area of economy/science which constitutes a new, growing economic specialisation based on utilising the unique natural resources of a region, connecting various branches of the industry, applying innovative technological solutions. Each Polish voivodeship has a specific list of smart specialisations aimed at creating new markets for economic activity, modernisation and increasing the region's competitiveness. Using as an example the technical universities in the Silesian Voivodeship, the author considers the possibility of teaching future experts for Smart Specialisation implementation as part of the Production Engineering course. He signalises the potential and omissions.
Buffelgrass-Integrated modeling of an invasive plant
Holcombe, Tracy R.
2011-01-01
Buffelgrass (Pennisetum ciliare) poses a problem in the deserts of the United States, growing in dense stands and introducing a wildfire risk in an ecosystem not adapted to fire. The Invasive Species Science Branch of the Fort Collins Science Center has worked with many partners to develop a decision support model and a data management system to address the problem. The decision support model evaluates potential strategies for resource use and allocation. The data management system is a portal where users can submit, view, and download buffelgrass data. These tools provide a case study showcasing how the FORT is working to address the urgent issue of invasive species in the United States.
Determinate growth and modularity in a gorgonian octocoral.
Lasker, Howard R; Boller, Michael L; Castanaro, John; Sánchez, Juan Armando
2003-12-01
Growth rates of branches of colonies of the gorgonian Pseudopterogorgia elisabethae were monitored for 2 years on a reef at San Salvador Island, Bahamas. Images of 261 colonies were made at 6-month intervals and colony and branch growth analyzed. Branch growth rates differed between colonies and between the time intervals in which the measurements were made. Colonies developed a plumelike morphology through a pattern of branch origination and determinate growth in which branch growth rates were greatest at the time the branch originated and branches seldom grew beyond a length of 8 cm. A small number of branches had greater growth rates, did not stop growing, and were sites for the origination of subsequent "generations" of branches. The rate of branch origination decreased with each generation of branching, and branch growth rates were lower on larger colonies, leading to determinate colony growth. Although colonial invertebrates like P. elisabethae grow through the addition of polyps, branches behave as modules with determinate growth. Colony form and size is generated by the iterative addition of branches.
77 FR 65351 - Missouri: Authorization of State Hazardous Waste Management Program Revisions
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-26
...: Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental Protection Agency (EPA... Jackson-Johnson, Environmental Protection Agency, Waste Enforcement & Materials Management Branch, 11201... its hazardous waste program under the Resource Conservation and Recovery Act (RCRA). EPA proposes to...
... Intimate Partner and Sexual Violence Survey National Sexual Violence Resource Center Features Media Sign up for Features Get Email Updates To ... Center for Injury Prevention and Control, Division of Violence Prevention Page maintained by: Office of the Associate Director for Communication, Digital Media Branch, Division of Public Affairs ... ...
Civil Division - Alaska Department of Law
Attorney General Opinions Executive Branch Ethics Criminal Justice Alaska Medicaid Fraud Control Anchorage department and other agencies on the management, retention, communication, and disclosure of information matters. In addition, the legislative liaison coordinates responses to media requests. Natural Resources
24 CFR 3280.804 - Disconnecting means and branch-circuit protective equipment.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Disconnecting means and branch... SAFETY STANDARDS Electrical Systems § 3280.804 Disconnecting means and branch-circuit protective equipment. (a) The branch-circuit equipment is permitted to be combined with the disconnecting means as a...
Integrating Agriculture and Conservation
Vandever, Mark W.
2010-01-01
The USGS produces the needed science-based information to guide management actions and policy decisions that support wildlife habitat and other environmental services compatible with USDA conservation goals and farm operations. The Policy Analysis and Science Assistance Branch of the Fort Collins Science Center (FORT) has conducted research involving a national landowner survey and numerous short- and long-term evaluations regarding vegetation responses to land management practices. This research helps land and resource managers to make informed decisions and resolve resource management conflicts.
LTN Inlets and Nozzles Branch Overview; NASA GE - Methods Development Review
NASA Technical Reports Server (NTRS)
Long-Davis, Mary Jo
2017-01-01
LTNInlets and Nozzles Branch Overview to be presented to GE during method review meeting. Presentation outlines the capabilities, facilities and tools used by the LTN Branch to conduct its mission of developing design and analysis tools and technologies for inlets and nozzles used on advanced vehicle concepts ranging from subsonic to hypersonic speeds.
NASA Astrophysics Data System (ADS)
Lu, Yuan-Yuan; Wang, Ji-Bo; Ji, Ping; He, Hongyu
2017-09-01
In this article, single-machine group scheduling with learning effects and convex resource allocation is studied. The goal is to find the optimal job schedule, the optimal group schedule, and resource allocations of jobs and groups. For the problem of minimizing the makespan subject to limited resource availability, it is proved that the problem can be solved in polynomial time under the condition that the setup times of groups are independent. For the general setup times of groups, a heuristic algorithm and a branch-and-bound algorithm are proposed, respectively. Computational experiments show that the performance of the heuristic algorithm is fairly accurate in obtaining near-optimal solutions.
High-Temperature, Thin-Film Ceramic Thermocouples Developed
NASA Technical Reports Server (NTRS)
Sayir, Ali; Blaha, Charles A.; Gonzalez, Jose M.
2005-01-01
To enable long-duration, more distant human and robotic missions for the Vision for Space Exploration, as well as safer, lighter, quieter, and more fuel efficient vehicles for aeronautics and space transportation, NASA is developing instrumentation and material technologies. The high-temperature capabilities of thin-film ceramic thermocouples are being explored at the NASA Glenn Research Center by the Sensors and Electronics Branch and the Ceramics Branch in partnership with Case Western Reserve University (CWRU). Glenn s Sensors and Electronics Branch is developing thin-film sensors for surface measurement of strain, temperature, heat flux, and surface flow in propulsion system research. Glenn s Ceramics Branch, in conjunction with CWRU, is developing structural and functional ceramic technology for aeropropulsion and space propulsion.
A branching morphogenesis program governs embryonic growth of the thyroid gland
Liang, Shawn; Johansson, Ellen; Barila, Guillermo; Altschuler, Daniel L.; Fagman, Henrik
2018-01-01
ABSTRACT The developmental program that regulates thyroid progenitor cell proliferation is largely unknown. Here, we show that branching-like morphogenesis is a driving force to attain final size of the embryonic thyroid gland in mice. Sox9, a key factor in branching organ development, distinguishes Nkx2-1+ cells in the thyroid bud from the progenitors that originally form the thyroid placode in anterior endoderm. As lobes develop the thyroid primordial tissue branches several generations. Sox9 and Fgfr2b are co-expressed distally in the branching epithelium prior to folliculogenesis. The thyroid in Fgf10 null mutants has a normal shape but is severely hypoplastic. Absence of Fgf10 leads to defective branching and disorganized angiofollicular units although Sox9/Fgfr2b expression and the ability of cells to differentiate and form nascent follicles are not impaired. These findings demonstrate a novel mechanism of thyroid development reminiscent of the Fgf10-Sox9 program that characterizes organogenesis in classical branching organs, and provide clues to aid understanding of how the endocrine thyroid gland once evolved from an exocrine ancestor present in the invertebrate endostyle. PMID:29361553
A branching morphogenesis program governs embryonic growth of the thyroid gland.
Liang, Shawn; Johansson, Ellen; Barila, Guillermo; Altschuler, Daniel L; Fagman, Henrik; Nilsson, Mikael
2018-01-25
The developmental program that regulates thyroid progenitor cell proliferation is largely unknown. Here, we show that branching-like morphogenesis is a driving force to attain final size of the embryonic thyroid gland in mice. Sox9, a key factor in branching organ development, distinguishes Nkx2-1 + cells in the thyroid bud from the progenitors that originally form the thyroid placode in anterior endoderm. As lobes develop the thyroid primordial tissue branches several generations. Sox9 and Fgfr2b are co-expressed distally in the branching epithelium prior to folliculogenesis. The thyroid in Fgf10 null mutants has a normal shape but is severely hypoplastic. Absence of Fgf10 leads to defective branching and disorganized angiofollicular units although Sox9/Fgfr2b expression and the ability of cells to differentiate and form nascent follicles are not impaired. These findings demonstrate a novel mechanism of thyroid development reminiscent of the Fgf10-Sox9 program that characterizes organogenesis in classical branching organs, and provide clues to aid understanding of how the endocrine thyroid gland once evolved from an exocrine ancestor present in the invertebrate endostyle. © 2018. Published by The Company of Biologists Ltd.
Structural Mechanics and Dynamics Branch
NASA Technical Reports Server (NTRS)
Stefko, George
2003-01-01
The 2002 annual report of the Structural Mechanics and Dynamics Branch reflects the majority of the work performed by the branch staff during the 2002 calendar year. Its purpose is to give a brief review of the branch s technical accomplishments. The Structural Mechanics and Dynamics Branch develops innovative computational tools, benchmark experimental data, and solutions to long-term barrier problems in the areas of propulsion aeroelasticity, active and passive damping, engine vibration control, rotor dynamics, magnetic suspension, structural mechanics, probabilistics, smart structures, engine system dynamics, and engine containment. Furthermore, the branch is developing a compact, nonpolluting, bearingless electric machine with electric power supplied by fuel cells for future "more electric" aircraft. An ultra-high-power-density machine that can generate projected power densities of 50 hp/lb or more, in comparison to conventional electric machines, which generate usually 0.2 hp/lb, is under development for application to electric drives for propulsive fans or propellers. In the future, propulsion and power systems will need to be lighter, to operate at higher temperatures, and to be more reliable in order to achieve higher performance and economic viability. The Structural Mechanics and Dynamics Branch is working to achieve these complex, challenging goals.
Miura, Jiro; Sakai, Manabu; Uchida, Hitoshi; Nakamura, Wataru; Nohara, Kanji; Maruyama, Yusuke; Hattori, Atsuhiko; Sakai, Takayoshi
2015-01-01
Many organs, including salivary glands, lung, and kidney, are formed by epithelial branching during embryonic development. Branching morphogenesis occurs via either local outgrowths or the formation of clefts that subdivide epithelia into buds. This process is promoted by various factors, but the mechanism of branching morphogenesis is not fully understood. Here we have defined melatonin as a potential negative regulator or “brake” of branching morphogenesis, shown that the levels of it and its receptors decline when branching morphogenesis begins, and identified the process that it regulates. Melatonin has various physiological functions, including circadian rhythm regulation, free-radical scavenging, and gonadal development. Furthermore, melatonin is present in saliva and may have an important physiological role in the oral cavity. In this study, we found that the melatonin receptor is highly expressed on the acinar epithelium of the embryonic submandibular gland. We also found that exogenous melatonin reduces salivary gland size and inhibits branching morphogenesis. We suggest that this inhibition does not depend on changes in either proliferation or apoptosis, but rather relates to changes in epithelial cell adhesion and morphology. In summary, we have demonstrated a novel function of melatonin in organ formation during embryonic development. PMID:25876057
A tool for simulating parallel branch-and-bound methods
NASA Astrophysics Data System (ADS)
Golubeva, Yana; Orlov, Yury; Posypkin, Mikhail
2016-01-01
The Branch-and-Bound method is known as one of the most powerful but very resource consuming global optimization methods. Parallel and distributed computing can efficiently cope with this issue. The major difficulty in parallel B&B method is the need for dynamic load redistribution. Therefore design and study of load balancing algorithms is a separate and very important research topic. This paper presents a tool for simulating parallel Branchand-Bound method. The simulator allows one to run load balancing algorithms with various numbers of processors, sizes of the search tree, the characteristics of the supercomputer's interconnect thereby fostering deep study of load distribution strategies. The process of resolution of the optimization problem by B&B method is replaced by a stochastic branching process. Data exchanges are modeled using the concept of logical time. The user friendly graphical interface to the simulator provides efficient visualization and convenient performance analysis.
78 FR 25678 - Georgia: Final Authorization of State Hazardous Waste Management Program Revisions
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-02
...: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... of changes to its hazardous waste program under the Resource Conservation and Recovery Act (RCRA... Gwendolyn Gleaton, Permits and State Programs Section, RCRA Programs and Materials Management Branch, RCRA...
24 CFR 214.103 - Approval criteria.
Code of Federal Regulations, 2011 CFR
2011-04-01
... and public community resources to which it can refer clients who need help the agency cannot offer... counseling agencies, branches, and affiliates that are included in one application: (a) Nonprofit and tax... intermediary's approval application, and to participate in the HUD-approved portion of the intermediary's, SHFA...
24 CFR 214.103 - Approval criteria.
Code of Federal Regulations, 2013 CFR
2013-04-01
... and public community resources to which it can refer clients who need help the agency cannot offer... counseling agencies, branches, and affiliates that are included in one application: (a) Nonprofit and tax... intermediary's approval application, and to participate in the HUD-approved portion of the intermediary's, SHFA...
24 CFR 214.103 - Approval criteria.
Code of Federal Regulations, 2014 CFR
2014-04-01
... and public community resources to which it can refer clients who need help the agency cannot offer... counseling agencies, branches, and affiliates that are included in one application: (a) Nonprofit and tax... intermediary's approval application, and to participate in the HUD-approved portion of the intermediary's, SHFA...
24 CFR 214.103 - Approval criteria.
Code of Federal Regulations, 2012 CFR
2012-04-01
... and public community resources to which it can refer clients who need help the agency cannot offer... counseling agencies, branches, and affiliates that are included in one application: (a) Nonprofit and tax... intermediary's approval application, and to participate in the HUD-approved portion of the intermediary's, SHFA...
24 CFR 214.103 - Approval criteria.
Code of Federal Regulations, 2010 CFR
2010-04-01
... and public community resources to which it can refer clients who need help the agency cannot offer... counseling agencies, branches, and affiliates that are included in one application: (a) Nonprofit and tax... intermediary's approval application, and to participate in the HUD-approved portion of the intermediary's, SHFA...
76 FR 55057 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-06
... Records. System location: U.S. Army Human Resources Command, Education Incentives Branch, 1600 Spearhead... Social Security Number (SSN); Military Occupational Specialty (MOS). Student Loan: Qualifying student loan name, amount of loan, date of loan transaction, student education loan number assigned by the...
Short papers of the U.S. Geological Survey uranium-thorium symposium, 1977
Campbell, John A.
1977-01-01
This circular contains expanded abstracts for the technical papers presented at the 1977 Uranium and Thorium Research and Resources Conference, sponsored by the Branch of Uranium and Thorium Resources, U.S. Geological Survey. This Conference was held April 27 and 28, 1977, at the Colorado School of Mines, Golden. This was the second conference sponsored by the Branch the first was held in December of 1975.Readers interested in additional information about a paper presented at the meeting should contact the author directly. U.S. Geological Survey authors stationed in Denver can be reached by writing to Box 25046, Denver Federal Center, Denver, Colorado 80225. Authors stationed in Reston, Virginia, can be reached by writing to the U.S. Geological Survey, National Center, 12201 Sunrise Valley Drive, Reston, Virginia 22092. Current addresses for other authors appear at the beginning of their papers.Any use of trade names and trademarks in this publication is for descriptive purposes only and does not constitute endorsement by the U.S. Geological Survey.
Tomlinson, P. B.; Huggett, Brett A.
2011-01-01
Background and Aims Conifers are characterized by the paucity of axillary buds which in dicotyledonous trees usually occur at every node. To compensate, conifers also produce ‘axillary meristems’, which may be stimulated to late development. In juvenile material of Wollemia nobilis (Araucariaceae: Massart's model) first-order (plagiotropic) branches lack both axillary buds and, seemingly, axillary meristems. This contrasts with orthotropic (trunk) axes, which produce branches, either within the terminal bud or as reiterated orthotropic axes originating from axillary meristems. However, plagiotropic axes do produce branches if they are decapitated. This study investigated how this can occur if axillary meristems are not the source. Methods The terminal buds of a series of plagiotropic branches on juvenile trees were decapitated in order to generate axillary shoots. Shoots were culled at about weekly intervals to obtain stages in lateral shoot development. Serial sections were cut with a sliding microtome from the distal end of each sample and scanned sequentially for evidence of axillary meristems and early bud development. Key Results Anatomical search produced no clear evidence of pre-existing axillary meristems but did reveal stages of bud initiation. Buds were initiated in a group of small starch-rich cortical cells. Further development involved de-differentiation of these small cells and the development of contrasting outer and inner regions. The outer part becomes meristematic and organizes the apex of the new branch. The inner part develops a callus-like tissue of vacuolated cells within which vascular cambia are developed. This kind of insertion of a branch on the parent axis seems not to have been described before. Conclusions Axillary meristems in Wollemia characterize the leaf axils of trunk axes so that the origin of reiterated shoots is clear. Plagiotropic axes seemingly lack axillary meristems but still produce axillary branches by distinctive developmental processes. These observations demonstrate limited understanding of branch initiation in trees generally. PMID:21335327
Growth and development of Frankia spp. strain CcI3 at the single-hypha level in liquid culture.
Huang, Ying; Benson, David R
2012-01-01
Filamentous actinobacteria from the genus Frankia grow by hyphal tip extension and branching. The growth kinetics and branching pattern of Frankia are not well studied, especially at the early stages of mycelial development. Here, we compare the growth of Frankia sp. strain CcI3 in liquid cultures with and without proteose peptone #3 (PP3) using time-lapse photomicrography and image analysis. Individual hyphae showed a pseudolinear increase in length at early stages of development, whereas at the mycelial level, the aggregate length of hyphae described an exponential rate before slowing. Growth based on optical density or microscopic observations was similar in medium with or without PP3. However, PP3 altered the pattern of mycelial development by increasing branching. Distances between the hyphal apex and first branches were on average shorter in PP3-containing media. The final interbranch distances were also shorter in PP3 medium indicating that hyphae tended to branch earlier and more often when supplemented with PP3 to give a more compact mycelium. Vesicle development in nitrogen-fixing cultures limited cell expansion as a result of vesicles truncating growth on new branches. The results provide some explanation for the growth kinetics of Frankia and some indication of how growth rates may be improved.
Stability of synchrony against local intermittent fluctuations in tree-like power grids
NASA Astrophysics Data System (ADS)
Auer, Sabine; Hellmann, Frank; Krause, Marie; Kurths, Jürgen
2017-12-01
90% of all Renewable Energy Power in Germany is installed in tree-like distribution grids. Intermittent power fluctuations from such sources introduce new dynamics into the lower grid layers. At the same time, distributed resources will have to contribute to stabilize the grid against these fluctuations in the future. In this paper, we model a system of distributed resources as oscillators on a tree-like, lossy power grid and its ability to withstand desynchronization from localized intermittent renewable infeed. We find a remarkable interplay of the network structure and the position of the node at which the fluctuations are fed in. An important precondition for our findings is the presence of losses in distribution grids. Then, the most network central node splits the network into branches with different influence on network stability. Troublemakers, i.e., nodes at which fluctuations are especially exciting the grid, tend to be downstream branches with high net power outflow. For low coupling strength, we also find branches of nodes vulnerable to fluctuations anywhere in the network. These network regions can be predicted at high confidence using an eigenvector based network measure taking the turbulent nature of perturbations into account. While we focus here on tree-like networks, the observed effects also appear, albeit less pronounced, for weakly meshed grids. On the other hand, the observed effects disappear for lossless power grids often studied in the complex system literature.
A.R. Weiskittel; D. Maguire; R.A. Monserud
2007-01-01
Static models of individual tree crown attributes such as height to crown base and maximum branch diameter profile have been developed for several commercially important species. Dynamic models of individual branch growth and mortality have received less attention, but have generally been developed retrospectively by dissecting felled trees; however, this approach is...
Abscisic acid signaling is controlled by a BRANCHED1/HD-ZIP I cascade in Arabidopsis axillary buds.
González-Grandío, Eduardo; Pajoro, Alice; Franco-Zorrilla, José M; Tarancón, Carlos; Immink, Richard G H; Cubas, Pilar
2017-01-10
Shoot-branching patterns determine key aspects of plant life and are important targets for crop breeding. However, we are still largely ignorant of the genetic networks controlling locally the most important decision during branch development: whether the axillary bud, or branch primordium, grows out to give a lateral shoot or remains dormant. Here we show that, inside the buds, the TEOSINTE BRANCHED1, CYCLOIDEA, PCF (TCP) transcription factor BRANCHED1 (BRC1) binds to and positively regulates the transcription of three related Homeodomain leucine zipper protein (HD-ZIP)-encoding genes: HOMEOBOX PROTEIN 21 (HB21), HOMEOBOX PROTEIN 40 (HB40), and HOMEOBOX PROTEIN 53 (HB53). These three genes, together with BRC1, enhance 9-CIS-EPOXICAROTENOID DIOXIGENASE 3 (NCED3) expression, lead to abscisic acid accumulation, and trigger hormone response, thus causing suppression of bud development. This TCP/HD-ZIP genetic module seems to be conserved in dicot and monocotyledonous species to prevent branching under light-limiting conditions.
Programmable growth of branched silicon nanowires using a focused ion beam.
Jun, Kimin; Jacobson, Joseph M
2010-08-11
Although significant progress has been made in being able to spatially define the position of material layers in vapor-liquid-solid (VLS) grown nanowires, less work has been carried out in deterministically defining the positions of nanowire branching points to facilitate more complicated structures beyond simple 1D wires. Work to date has focused on the growth of randomly branched nanowire structures. Here we develop a means for programmably designating nanowire branching points by means of focused ion beam-defined VLS catalytic points. This technique is repeatable without losing fidelity allowing multiple rounds of branching point definition followed by branch growth resulting in complex structures. The single crystal nature of this approach allows us to describe resulting structures with linear combinations of base vectors in three-dimensional (3D) space. Finally, by etching the resulting 3D defined wire structures branched nanotubes were fabricated with interconnected nanochannels inside. We believe that the techniques developed here should comprise a useful tool for extending linear VLS nanowire growth to generalized 3D wire structures.
Price, Don
1961-01-01
An investigation of the ground-water resources of the northern Willamette Valley was begun in 1960 as a cooperative program between the Ground Water Branch, U.S. Geological Survey, and the Oregon State Engineer. The northern Willamette Valley area is one of the fastest growing areas of ground-water use within the state. The purpose of the investigation is to obtain an understanding of the availability, movement, and chemical quality of the ground-water resources of the area. This information is needed to attain an optimum development of the ground-water resources of the area and to aid in the prevention of problems of overdevelopment and pollution. The first phase of the program was the collection of well records, water level records, and chemical quality data in the central part of this area, which is known as the French Prairie-Mission Bottom area. The records collected in this phase of the study are essential in the preparation of an interpretive report describing the occurrence and movement of ground-water in the French Prairie-Mission Bottom area. These records, which will not be included in the interpretive report that is being prepared at this time, are being made available in this publication to aid in the location and the development of the ground-water resources of the area, and to serve as a supplement to the forthcoming interpretive report.
The human resource information system: a rapid appraisal of Pakistan’s capacity to employ the tool
2013-01-01
Background Human resources are an important building block of the health system. During the last decade, enormous investment has gone into the information systems to manage human resources, but due to the lack of a clear vision, policy, and strategy, the results of these efforts have not been very visible. No reliable information portal captures the actual state of human resources in Pakistan’s health sector. The World Health Organization (WHO) has provided technical support for the assessment of the existing system and development of a comprehensive Human Resource Information System (HRIS) in Pakistan. Methods The questions in the WHO-HRIS Assessment tool were distributed into five thematic groups. Purposively selected (n=65) representatives from the government, private sector, and development partners participated in this cross sectional study, based on their programmatic affiliations. Results Fifty-five percent of organizations and departments have an independent Human Resources (HR) section managed by an establishment branch and are fully equipped with functional computers. Forty-five organizations (70%) had HR rules, regulations and coordination mechanisms, yet these are not implemented. Data reporting is mainly in paper form, on prescribed forms (51%), registers (3%) or even plain papers (20%). Data analysis does not give inputs to the decision making process and dissemination of information is quite erratic. Most of the organizations had no feedback mechanism for cross checking the HR data, rendering it unreliable. Conclusion Pakistan is lacking appropriate HRIS management. The current HRIS indeed has a multitude of problems. In the wake of 2011 reforms within the health sector, provinces are even in a greater need for planning their respective health department services and must work on the deficiencies and inefficiencies of their HRIS so that the gaps and HR needs are better aligned for reaching the 2015 UN Millennium Development Goals (MDGs) targets. PMID:24016066
Fanwoua, Julienne; Bairam, Emna; Delaire, Mickael; Buck-Sorlin, Gerhard
2014-01-01
Understanding the role of branch architecture in carbon production and allocation is essential to gain more insight into the complex process of assimilate partitioning in fruit trees. This mini review reports on the current knowledge of the role of branch architecture in carbohydrate production and partitioning in apple. The first-order carrier branch of apple illustrates the complexity of branch structure emerging from bud activity events and encountered in many fruit trees. Branch architecture influences carbon production by determining leaf exposure to light and by affecting leaf internal characteristics related to leaf photosynthetic capacity. The dynamics of assimilate partitioning between branch organs depends on the stage of development of sources and sinks. The sink strength of various branch organs and their relative positioning on the branch also affect partitioning. Vascular connections between branch organs determine major pathways for branch assimilate transport. We propose directions for employing a modeling approach to further elucidate the role of branch architecture on assimilate partitioning. PMID:25071813
1992-11-01
OF ENGINEERS P.O. BOX 60267 NEW ORLEANS. LOUISIANA 70160-0267 REPLY TO ATTENTIONOF: May 5, 1992 Planning Division Environmental Analysis Branch To The...tools used for exploiting botanical as well as faunal resources. This includes mortars, pestles , and mealing stones (Rue 1990). The atlatl, or spear...included the J.A. Bently Lumber Co., Urania Lumber Co., Bodcaw Lumber Co., and Industrial Lumber Co. The expansion of the lumber industry directly related
Keyword: help! Online resources for disaster preparedness.
Hart, Amadie H; Cushman, Margaret J
2002-01-01
Health care organizations such as home care agencies should have post-disaster contingency plans in place that include contacts with the local, county, or state emergency management office, local branch of the Red Cross, and a clearly identified point person within the agency to coordinate disaster response efforts. Home care agencies must plan for the far-reaching effects that disasters can have on people in the community. This article provides some online resources to help you, your organization, and your family prepare for unexpected events.
Epicormic Branches and Lumber Grade of Bottomland Oak
James S. Meadows
1995-01-01
Epicormic branches can be a serious problem in management of hardwood forests for high-quality sawtimber production. In one study in central Alabama, defects caused by epicormic branches that developed following a partial cutting resulted in a 13 percent reduction in the value of willow oak lumber. Production of epicormic branches along the boles of hardwood trees is...
Ruthazer, Edward S; Bachleda, Amelia R; Olavarria, Jaime F
2010-12-15
We combined fixed-tissue and time-lapse analyses to investigate the axonal branching phenomena underlying the development of topographically organized ipsilateral projections from area 17 to area 18a in the rat. These complementary approaches allowed us to relate static, large-scale information provided by traditional fixed-tissue analysis to highly dynamic, local, small-scale branching phenomena observed with two-photon time-lapse microscopy in acute slices of visual cortex. Our fixed-tissue data revealed that labeled area 17 fibers invaded area 18a gray matter at topographically restricted sites, reaching superficial layers in significant numbers by postnatal day 6 (P6). Moreover, most parental axons gave rise to only one or occasionally a small number of closely spaced interstitial branches beneath 18a. Our time-lapse data showed that many filopodium-like branches emerged along parental axons in white matter or deep layers in area 18a. Most of these filopodial branches were transient, often disappearing after several minutes to hours of exploratory extension and retraction. These dynamic behaviors decreased significantly from P4, when the projection is first forming, through the second postnatal week, suggesting that the expression of, or sensitivity to, cortical cues promoting new branch addition in the white matter is developmentally down-regulated coincident with gray matter innervation. Together, these data demonstrate that the development of topographically organized corticocortical projections in rats involves extensive exploratory branching along parental axons and invasion of cortex by only a small number of interstitial branches, rather than the widespread innervation of superficial cortical layers by an initially exuberant population of branches. © 2010 Wiley-Liss, Inc.
Ruthazer, Edward S.; Bachleda, Amelia R.; Olavarria, Jaime F.
2013-01-01
We combined fixed-tissue and time-lapse analyses to investigate the axonal branching phenomena underlying the development of topographically organized ipsilateral projections from area 17 to area 18a in the rat. These complementary approaches allowed us to relate static, large-scale information provided by traditional fixed-tissue analysis to highly dynamic, local, small-scale branching phenomena observed with two-photon time-lapse microscopy in acute slices of visual cortex. Our fixed-tissue data revealed that labeled area 17 fibers invaded area 18a gray matter at topographically restricted sites, reaching superficial layers in significant numbers by postnatal day 6 (P6). Moreover, most parental axons gave rise to only one or occasionally a small number of closely spaced interstitial branches beneath 18a. Our time-lapse data showed that many filopodium-like branches emerged along parental axons in white matter or deep layers in area 18a. Most of these filopo-dial branches were transient, often disappearing after several minutes to hours of exploratory extension and retraction. These dynamic behaviors decreased significantly from P4, when the projection is first forming, through the second postnatal week, suggesting that the expression of, or sensitivity to, cortical cues promoting new branch addition in the white matter is developmentally down-regulated coincident with gray matter innervation. Together, these data demonstrate that the development of topographically organized corticocortical projections in rats involves extensive exploratory branching along parental axons and invasion of cortex by only a small number of interstitial branches, rather than the widespread innervation of superficial cortical layers by an initially exuberant population of branches. PMID:21031561
Benson, Helen E; Sharman, Joanna L; Mpamhanga, Chido P; Parton, Andrew; Southan, Christopher; Harmar, Anthony J; Ghazal, Peter
2017-01-01
Background and Purpose An ever‐growing wealth of information on current drugs and their pharmacological effects is available from online databases. As our understanding of systems biology increases, we have the opportunity to predict, model and quantify how drug combinations can be introduced that outperform conventional single‐drug therapies. Here, we explore the feasibility of such systems pharmacology approaches with an analysis of the mevalonate branch of the cholesterol biosynthesis pathway. Experimental Approach Using open online resources, we assembled a computational model of the mevalonate pathway and compiled a set of inhibitors directed against targets in this pathway. We used computational optimization to identify combination and dose options that show not only maximal efficacy of inhibition on the cholesterol producing branch but also minimal impact on the geranylation branch, known to mediate the side effects of pharmaceutical treatment. Key Results We describe serious impediments to systems pharmacology studies arising from limitations in the data, incomplete coverage and inconsistent reporting. By curating a more complete dataset, we demonstrate the utility of computational optimization for identifying multi‐drug treatments with high efficacy and minimal off‐target effects. Conclusion and Implications We suggest solutions that facilitate systems pharmacology studies, based on the introduction of standards for data capture that increase the power of experimental data. We propose a systems pharmacology workflow for the refinement of data and the generation of future therapeutic hypotheses. PMID:28910500
The effect of nanotechnology on education
NASA Astrophysics Data System (ADS)
Viriyavejakul, Chantana
2008-04-01
The research objective was to study 1) the situation and readiness of the Thai education for the integration of nanotechnology and 2) to propose the plans, the strategies and guidelines for educational reform to adapt nanotechnology to the system. The data collection was done by 4 methods: 1) documentary study, 2) observation, 3) informal interviews, and 4) group discussion. The findings revealed that: 1. William Wresch's Theory (1997) was used in this research to study of the situation and readiness of the Thai education for the integration of nanotechnology. 1) Getting connected to nanotechnology by search engine websites, libraries, magazines, books, and discussions with experts. 2) Curriculum integration: nanotechnology should be integrated in many branches of engineering, such as industrial, computer, civil, chemical, electrical, mechanical, etc. 3) Resources for educators: nanotechnology knowledge should be spread in academic circles by publications and the Internet websites. 4) Training and professional resources for teachers: Teachers should be trained by experts in nanotechnology and researchers from the National Nanotechnology Center. This will help trainees get correct knowledge, comprehension, and awareness in order to apply to their professions and businesses in the future. 2. As for the plans, the strategies, and guidelines for educational reform to adapt nanotechnology to the present system, I analyzed the world nanotechnology situation that might have an effect on Thai society. The study is based on the National Plan to Develop Nanotechnology. The goal of this plan is to develop nanotechnology to be the national strategy within 10 years (2004-2013) and have it integrated into the Thai system. There are 4 parts in this plan: 1) nanomaterials, 2) nanoelectronics, 3) nanobiotechnology, and 4) human resources development. Data for human resource development should be worked with the present technology and use the country's resources to produce many products of nanotechnology, such as 1) handicrafts, decorations, and gifts, 2) agricultural products and food, 3) beverages, such as alcoholic and non- alcoholic drinks, and 5) textiles.
Simulation of the evolution of root water foraging strategies in dry and shallow soils
Renton, Michael; Poot, Pieter
2014-01-01
Background and Aims The dynamic structural development of plants can be seen as a strategy for exploiting the limited resources available within their environment, and we would expect that evolution would lead to efficient strategies that reduce costs while maximizing resource acquisition. In particular, perennial species endemic to habitats with shallow soils in seasonally dry environments have been shown to have a specialized root system morphology that may enhance access to water resources in the underlying rock. This study aimed to explore these hypotheses by applying evolutionary algorithms to a functional–structural root growth model. Methods A simulation model of a plant's root system was developed, which represents the dynamics of water uptake and structural growth. The model is simple enough for evolutionary optimization to be computationally feasible, yet flexible enough to allow a range of structural development strategies to be explored. The model was combined with an evolutionary algorithm in order to investigate a case study habitat with a highly heterogeneous distribution of resources, both spatially and temporally – the situation of perennial plants occurring on shallow soils in seasonally dry environments. Evolution was simulated under two contrasting fitness criteria: (1) the ability to find wet cracks in underlying rock, and (2) maximizing above-ground biomass. Key Results The novel approach successfully resulted in the evolution of more efficient structural development strategies for both fitness criteria. Different rooting strategies evolved when different criteria were applied, and each evolved strategy made ecological sense in terms of the corresponding fitness criterion. Evolution selected for root system morphologies which matched those of real species from corresponding habitats. Conclusions Specialized root morphology with deeper rather than shallower lateral branching enhances access to water resources in underlying rock. More generally, the approach provides insights into both evolutionary processes and ecological costs and benefits of different plant growth strategies. PMID:24651371
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-07
... Carolina: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... authorization of the changes to its hazardous waste program under the Resource Conservation and Recovery Act... Section, RCRA Programs and Materials Management Branch, RCRA Division, U.S. Environmental Protection...
76 FR 6594 - Florida: Final Authorization of State Hazardous Waste Management Program Revisions
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-07
...: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... of the changes to its hazardous waste program under the Resource Conservation and Recovery Act (RCRA... and State Programs Section, RCRA Programs and Materials Management Branch, RCRA Division, U.S...
77 FR 60963 - Tennessee: Final Authorization of State Hazardous Waste Management Program Revisions
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-05
...: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... of the changes to its hazardous waste program under the Resource Conservation and Recovery Act (RCRA... Johnson, Permits and State Programs Section, RCRA Programs and Materials Management Branch, RCRA Division...
75 FR 79010 - National Cancer Institute; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-17
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... Cancer Institute Special Emphasis Panel Education. Date: January 25, 2011. Time: 3 p.m. to 4:30 p.m..., Resources and Training Review Branch, Division of Extramural Activities, National Cancer Institute, 6116...
78 FR 54255 - HRSA's Bureau of Health Professions Advanced Education Nursing Traineeship Program
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-03
... of Health Professions Advanced Education Nursing Traineeship Program AGENCY: Health Resources and... announcing a change to its Advanced Education Nursing Traineeship (AENT) program. Effective fiscal year (FY... Wasserman, DrPH, RN, Advanced Nursing Education Branch Chief, Division of Nursing, Bureau of Health...
NASA Astrophysics Data System (ADS)
Petersen, D.; Beasley, W. H.
2012-12-01
We present high-speed video, taken at 75,000 frames per second, of an anomalous lightning flash that involved two distinct return strokes from different branches of the same branched negative stepped leader system. During the initial return stroke the leader system was incompletely drained, resulting in the continued development of a large side branch. The upper portions of this side branch exhibited a pulse of luminosity during the initial return stroke, but the luminosity did not extend down the branch. The lower portion of the branch continued to develop downward as a negative stepped leader, but at a much slower velocity. Continued stepping activity was observed in this branch as it continued downward at a significantly reduced velocity, finally attaching to the earth 1.8 milliseconds after the main return stroke. The ensuing return stroke was characterized by a slower vertical velocity and weaker luminous pulse. Based on this observation, we coin the term "orphaned branch" to describe a branch of a leader system that is not drained during a return stroke. While our case involves a branch that eventually connected to the ground and produced a return stroke, we also consider the possibility that such branches may also simply cease to progress and effectively deposit large amounts of space charge near their extremities. Such space charge would have a strong influence on subsequent breakdown activity in their vicinity, such as shielding subsequent descending negative stepped leaders or triggering upward positive leaders from earth's surface.
ERIC Educational Resources Information Center
Ferguson, Richard L.
The focus of this study was upon the development and evaluation of a computer-assisted branched test to be used in making instructional decisions for individuals in the program of Individually Prescribed Instruction. A Branched Test is one in which the presentation of test items is contingent upon the previous responses of the examinee. The…
Fort Collins Science Center: Fiscal Year 2007 Accomplishments
Wilson, J.T.
2008-01-01
In Fiscal Year 2007 (FY07), the U.S. Geological Survey (USGS) Fort Collins Science Center (FORT) continued research vital to U.S. Department of the Interior science and management needs and associated USGS programmatic goals. FORT work also supported the science needs of other government agencies as well as private cooperators. Specifically, FORT scientific research and technical assistance focused on client and partner needs and goals in the areas of biological information management, fisheries and aquatic systems, invasive species, status and trends of biological resources, terrestrial ecosystems, and wildlife resources. In addition, FORT's 5-year strategic plan was refined to incorporate focus areas identified in the USGS strategic science plan, including ecosystem-landscape analysis, global climate change, and energy and mineral resource development. As a consequence, several science projects initiated in FY07 were either entirely new research dor amplifications of existing work. Highlights of FORT project accomplishments are described below under the USGS science program with which each task is most closely associated. The work of FORT's 6 branches (Aquatic Systems and Technology Applications, Ecosystem Dynamics, Information Science, Invasive Species Science, Policy Analysis and Science Assistance, and Species and Habitats of Federal Interest) often involves major partnerships with other agencies or cooperation with other USGS disciplines (Geology, Geography, Water Resources) and the Geospatial Information Office.
NASA Astrophysics Data System (ADS)
Calabrese, Michelle A.
Surfactant wormlike micelles (WLMs) are of particular scientific interest due to their ability to branch, break, and reform under shear, which can lead to shear banding flow instabilities. The tunable self-assembly of WLMs makes them ubiquitous in applications ranging from consumer products to energy recovery fluids. Altering the topology of WLMs by inducing branching provides a microstructural pathway to design and optimize the flow properties for such targeted applications. The goal of this thesis is to understand the role of micellar branching on the resulting equilibrium and non-equilibrium properties, while advancing instrumentation and analysis methods in rheology and neutron scattering. The degree of branching in the mixed cationic/anionic surfactant solutions is controlled by the addition of sodium tosylate. The equilibrium properties are characterized via small angle neutron scattering (SANS), linear viscoelastic rheology, neutron spin echo, and dynamic light scattering. Combining rheology with spatiotemporally-resolved SANS enables unambiguous identification of non-equilibrium rheological and scattering signatures of branching and shear banding. The nonlinear WLM response is characterized via flow-SANS under steady shear, shear startup, and large amplitude oscillatory shear. New methods of time-resolved data analysis are developed, which improve experimental resolution by several-fold. Shear-induced orientation is a complex function of branching level, radial position, and deformation type. The structural mechanisms behind shear band formation are elucidated for steady and dynamic flows, which depend on branching level. Shear banding disappears at high branching levels for all deformation types. These responses are used to validate constitutive modeling predictions of dynamic shear banding for the first time. Finally, quantitative metrics to predict shear banding from rheology or flow-induced orientation are developed. Together, advanced rheological and neutron techniques provide a platform for creating structure-property relationships that predict flow and structural phenomena in WLMs and other soft materials. These methods have enabled characteristic differences in linear versus branched WLMs to be determined. This research is part of a broader effort to characterize branching in polymers and self-assembled systems, and may aid in the formulation of WLMs for specific applications. Finally, this work provides a basis for testing and developing microstructure-based constitutive equations that incorporate micellar breakage and branching.
Wemple, B.; Shanley, J.; Denner, J.; Ross, D.; Mills, K.
2007-01-01
Mountain regions throughout the world face intense development pressures associated with recreational and tourism uses. Despite these pressures, much of the research on bio-geophysical impacts of humans in mountain regions has focused on the effects of natural resource extraction. This paper describes findings from the first 3 years of a study examining high elevation watershed processes in a region undergoing alpine resort development. Our study is designed as a paired-watershed experiment. The Ranch Brook watershed (9.6 km2) is a relatively pristine, forested watershed and serves as the undeveloped 'control' basin. West Branch (11.7 km2) encompasses an existing alpine ski resort, with approximately 17% of the basin occupied by ski trails and impervious surfaces, and an additional 7% slated for clearing and development. Here, we report results for water years 2001-2003 of streamflow and water quality dynamics for these watersheds. Precipitation increases significantly with elevation in the watersheds, and winter precipitation represents 36-46% of annual precipitation. Artificial snowmaking from water within West Branch watershed currently augments annual precipitation by only 3-4%. Water yield in the developed basin exceeded that in the control by 18-36%. Suspended sediment yield was more than two and a half times greater and fluxes of all major solutes were higher in the developed basin. Our study is the first to document the effects of existing ski area development on hydrology and water quality in the northeastern US and will serve as an important baseline for evaluating the effects of planned resort expansion activities in this area.
Cross-scale phenological data integration to benefit resource management and monitoring
Richardson, Andrew D.; Weltzin, Jake F.; Morisette, Jeffrey T.
2017-01-01
Climate change is presenting new challenges for natural resource managers charged with maintaining sustainable ecosystems and landscapes. Phenology, a branch of science dealing with seasonal natural phenomena (bird migration or plant flowering in response to weather changes, for example), bridges the gap between the biosphere and the climate system. Phenological processes operate across scales that span orders of magnitude—from leaf to globe and from days to seasons—making phenology ideally suited to multiscale, multiplatform data integration and delivery of information at spatial and temporal scales suitable to inform resource management decisions.A workshop report: Workshop held June 2016 to investigate opportunities and challenges facing multi-scale, multi-platform integration of phenological data to support natural resource management decision-making.
Lance S. Evans; Angela Citta; Stewart C. Sanderson
2012-01-01
Eccentricity of stems of Artemisia tridentata Nutt. (big sagebrush) has been reported previously. Analysis of samples observed over 2 years documented that each stem terminal produces about 8-10 branches each year, and during second-year growth, 3-8 of these develop into short, flowering, determinate branches. Each flowering branch produces hundreds of seeds and then...
The Utilization of Evaluation Research in Litigation.
ERIC Educational Resources Information Center
Saks, Michael J.
1980-01-01
The judicial branches of government have unique needs for evaluative information and limited resources; this must be recognized in order to increase the utilization of applied social research by courts and lawyers. (Available from: Jossey-Bass, Inc., 433 California St., San Francisco, CA 94104, single issue, $6.95.) (GDC)
78 FR 72715 - Proposed Revision and Extension of the Approval of Information Collection Requirements
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-03
... financial resources) is minimized, collection instruments are clearly understood, and the impact of...: [email protected] ; Mail, Hand Delivery, Courier: Regulatory Analysis Branch, Wage and Hour Division, U.S... experience delays in receiving mail in the Washington, DC area, commenters are strongly encouraged to...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-10
... Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC 20503 (202... for Training and Employment): Activity Under OMB Review AGENCY: Veterans Benefits Administration... . Please refer to ``OMB Control No. 2900-0677.'' SUPPLEMENTARY INFORMATION: Title: Contract for Training...
78 FR 48940 - Agency Information Collection (Designation of Beneficiary) Activities Under OMB Review
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-12
... Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC 20503 (202) 395-7316...-0020.'' SUPPLEMENTARY INFORMATION: Title: Designation of Beneficiary, Government Life Insurance, VA... optional settlement to be used when the Government Life Insurance matures by death. An agency may not...
Branches Global Climate & Weather Modeling Mesoscale Modeling Marine Modeling and Analysis Contact EMC , state and local government Web resources and services. Real-time, global, sea surface temperature (RTG_SST_HR) analysis For a regional map, click the desired area in the global SST analysis and anomaly maps
ERIC Educational Resources Information Center
Waller, David, Ed.; Nadel, Lynn, Ed.
2012-01-01
Spatial cognition is a branch of cognitive psychology that studies how people acquire and use knowledge about their environment to determine where they are, how to obtain resources, and how to find their way home. Researchers from a wide range of disciplines, including neuroscience, cognition, and sociology, have discovered a great deal about how…
30 CFR 75.1000 - Cutout switches.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Cutout switches. 75.1000 Section 75.1000... switches. [Statutory Provisions] Trolley wires and trolley feeder wires, shall be provided with cutout switches at intervals of not more than 2,000 feet and near the beginning of all branch lines. ...
30 CFR 75.1000 - Cutout switches.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Cutout switches. 75.1000 Section 75.1000... switches. [Statutory Provisions] Trolley wires and trolley feeder wires, shall be provided with cutout switches at intervals of not more than 2,000 feet and near the beginning of all branch lines. ...
30 CFR 75.1000 - Cutout switches.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Cutout switches. 75.1000 Section 75.1000... switches. [Statutory Provisions] Trolley wires and trolley feeder wires, shall be provided with cutout switches at intervals of not more than 2,000 feet and near the beginning of all branch lines. ...
Program PIA Program GO-FAAR Program Other Opportunities Tourism Visits to Tololo Astro tourism in Chile Tourism in Chile Information for travelers Visit Tololo Media Relations News Press Release Publications , and books, most of which can be found at CTIO's La Serena library branch. Electronic Resources Access
NWS Water Resource Services Branch Division
and Service Reports Waterloo, Iowa Stakeholder Report August 10, 2017 Greenville, North Carolina Stakeholder Report June 21, 2017 Maricopa County, Arizona Stakeholder Report April 19, 2017 Austin, Texas Stakeholder Report February 8, 2017 Final Russian River Basin Partner Report, January 2016 Flash Flood
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-09
... Primacy Application for National Primary Drinking Water Regulations for the State of Missouri AGENCY... Department of Natural Resources, Public Drinking Water Branch, 1101 Riverside Drive, Jefferson City, MO 65101. (2) Environmental Protection Agency-Region 7, Water Wetlands and Pesticides Division, Drinking Water...
Competing Interests, Economics, and Marine Fisheries Management: An Educational Case Study
ERIC Educational Resources Information Center
Thorson, James T.; Berkson, Jim; Murphy, Brian
2010-01-01
Managing fish resources in the ocean, known as marine fisheries management, often involves disagreement among many groups of people: commercial fishers, recreational anglers, national and local conservationists, and several branches of government. While managing marine fisheries in federal waters, the federal government must rebuild marine fish…
75 FR 45630 - Agency Information Collection Activities: Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-03
..., Human Resources and Housing Branch, Office of Management and Budget, New Executive Office Building, Room... DEPARTMENT OF HEALTH AND HUMAN SERVICES Substance Abuse and Mental Health Services Administration... Preventing Underage Drinking Act (the ``STOP Act'') \\1\\ states that the ``Secretary [of Health and Human...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-01
..., OMB Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC... to the Office of Management and Budget (OMB) for review and comment. The PRA submission describes the... approved collection. Abstracts: a. Educational institutions and job training establishments complete VA...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-16
... Officer, OMB Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC...-The-Job Training and Apprenticeship Training Agreement and Standards and Employer's Application To Provide Job Training) Activity Under OMB Review AGENCY: Veterans Benefits Administration, Department of...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-30
... the Health Care Quality Improvement Act of 1986 and administered by the Department of Health and Human... Officer, OMB Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0621] Agency Information Collection (National...
Linear and nonlinear dynamic analysis of redundant load path bearingless rotor systems
NASA Technical Reports Server (NTRS)
Murthy, V. R.; Shultz, Louis A.
1994-01-01
The goal of this research is to develop the transfer matrix method to treat nonlinear autonomous boundary value problems with multiple branches. The application is the complete nonlinear aeroelastic analysis of multiple-branched rotor blades. Once the development is complete, it can be incorporated into the existing transfer matrix analyses. There are several difficulties to be overcome in reaching this objective. The conventional transfer matrix method is limited in that it is applicable only to linear branch chain-like structures, but consideration of multiple branch modeling is important for bearingless rotors. Also, hingeless and bearingless rotor blade dynamic characteristics (particularly their aeroelasticity problems) are inherently nonlinear. The nonlinear equations of motion and the multiple-branched boundary value problem are treated together using a direct transfer matrix method. First, the formulation is applied to a nonlinear single-branch blade to validate the nonlinear portion of the formulation. The nonlinear system of equations is iteratively solved using a form of Newton-Raphson iteration scheme developed for differential equations of continuous systems. The formulation is then applied to determine the nonlinear steady state trim and aeroelastic stability of a rotor blade in hover with two branches at the root. A comprehensive computer program is developed and is used to obtain numerical results for the (1) free vibration, (2) nonlinearly deformed steady state, (3) free vibration about the nonlinearly deformed steady state, and (4) aeroelastic stability tasks. The numerical results obtained by the present method agree with results from other methods.
Child Development and Behavior Branch (CDBB), NIHCD, Report to the NACHHD Council
ERIC Educational Resources Information Center
National Institute of Child Health and Human Development (NICHD), 2009
2009-01-01
The Child Development & Behavior (CDB) Branch of the National Institute of Child Health and Human Development (NICHD) seeks to improve the health and well-being of individuals from infancy through early adulthood by supporting research into healthy growth and development, including all aspects of child development. The study of typical child…
ELIGULUM-A Regulates Lateral Branch and Leaf Development in Barley1[OPEN
Haaning, Allison; Bilgic, Hatice
2018-01-01
The shoot apical and axillary meristems control shoot development, effectively influencing lateral branch and leaf formation. The barley (Hordeum vulgare) uniculm2 (cul2) mutation blocks axillary meristem development, and mutant plants lack lateral branches (tillers) that normally develop from the crown. A genetic screen for cul2 suppressors recovered two recessive alleles of ELIGULUM-A (ELI-A) that partially rescued the cul2 tillering phenotype. Mutations in ELI-A produce shorter plants with fewer tillers and disrupt the leaf blade-sheath boundary, producing liguleless leaves and reduced secondary cell wall development in stems and leaves. ELI-A is predicted to encode an unannotated protein containing an RNaseH-like domain that is conserved in land plants. ELI-A transcripts accumulate at the preligule boundary, the developing ligule, leaf margins, cells destined to develop secondary cell walls, and cells surrounding leaf vascular bundles. Recent studies have identified regulatory similarities between boundary development in leaves and lateral organs. Interestingly, we observed ELI-A transcripts at the preligule boundary, suggesting that ELI-A contributes to boundary formation between the blade and sheath. However, we did not observe ELI-A transcripts at the axillary meristem boundary in leaf axils, suggesting that ELI-A is not involved in boundary development for axillary meristem development. Our results show that ELI-A contributes to leaf and lateral branch development by acting as a boundary gene during ligule development but not during lateral branch development. PMID:29440592
Lebon, Eric; Pellegrino, Anne; Tardieu, Francois; Lecoeur, Jeremie
2004-03-01
Shoot architecture variability in grapevine (Vitis vinifera) was analysed using a generic modelling approach based on thermal time developed for annual herbaceous species. The analysis of shoot architecture was based on various levels of shoot organization, including pre-existing and newly formed parts of the stem, and on the modular structure of the stem, which consists of a repeated succession of three phytomers (P0-P1-P2). Four experiments were carried out using the cultivar 'Grenache N': two on potted vines (one of which was carried out in a glasshouse) and two on mature vines in a vineyard. These experiments resulted in a broad diversity of environmental conditions, but none of the plants experienced soil water deficit. Development of the main axis was highly dependent on air temperature, being linearly related to thermal time for all stages of leaf development from budbreak to veraison. The stable progression of developmental stages along the main stem resulted in a thermal-time based programme of leaf development. Leaf expansion rate varied with trophic competition (shoot and cluster loads) and environmental conditions (solar radiation, VPD), accounting for differences in final leaf area. Branching pattern was highly variable. Classification of the branches according to ternary modular structure increased the accuracy of the quantitative analysis of branch development. The rate and duration of leaf production were higher for branches derived from P0 phytomers than for branches derived from P1 or P2 phytomers. Rates of leaf production, expressed as a -function of thermal time, were not stable and depended on trophic competition and environmental conditions such as solar radiation or VPD. The application to grapevine of a generic model developed in annual plants made it possible to identify constants in main stem development and to determine the hierarchical structure of branches with respect to the modular structure of the stem in response to intra- and inter-shoot trophic competition.
Partial branch and bound algorithm for improved data association in multiframe processing
NASA Astrophysics Data System (ADS)
Poore, Aubrey B.; Yan, Xin
1999-07-01
A central problem in multitarget, multisensor, and multiplatform tracking remains that of data association. Lagrangian relaxation methods have shown themselves to yield near optimal answers in real-time. The necessary improvement in the quality of these solutions warrants a continuing interest in these methods. These problems are NP-hard; the only known methods for solving them optimally are enumerative in nature with branch-and-bound being most efficient. Thus, the development of methods less than a full branch-and-bound are needed for improving the quality. Such methods as K-best, local search, and randomized search have been proposed to improve the quality of the relaxation solution. Here, a partial branch-and-bound technique along with adequate branching and ordering rules are developed. Lagrangian relaxation is used as a branching method and as a method to calculate the lower bound for subproblems. The result shows that the branch-and-bound framework greatly improves the resolution quality of the Lagrangian relaxation algorithm and yields better multiple solutions in less time than relaxation alone.
Turing mechanism underlying a branching model for lung morphogenesis.
Xu, Hui; Sun, Mingzhu; Zhao, Xin
2017-01-01
The mammalian lung develops through branching morphogenesis. Two primary forms of branching, which occur in order, in the lung have been identified: tip bifurcation and side branching. However, the mechanisms of lung branching morphogenesis remain to be explored. In our previous study, a biological mechanism was presented for lung branching pattern formation through a branching model. Here, we provide a mathematical mechanism underlying the branching patterns. By decoupling the branching model, we demonstrated the existence of Turing instability. We performed Turing instability analysis to reveal the mathematical mechanism of the branching patterns. Our simulation results show that the Turing patterns underlying the branching patterns are spot patterns that exhibit high local morphogen concentration. The high local morphogen concentration induces the growth of branching. Furthermore, we found that the sparse spot patterns underlie the tip bifurcation patterns, while the dense spot patterns underlies the side branching patterns. The dispersion relation analysis shows that the Turing wavelength affects the branching structure. As the wavelength decreases, the spot patterns change from sparse to dense, the rate of tip bifurcation decreases and side branching eventually occurs instead. In the process of transformation, there may exists hybrid branching that mixes tip bifurcation and side branching. Since experimental studies have reported that branching mode switching from side branching to tip bifurcation in the lung is under genetic control, our simulation results suggest that genes control the switch of the branching mode by regulating the Turing wavelength. Our results provide a novel insight into and understanding of the formation of branching patterns in the lung and other biological systems.
Odeh, Hana; Miranda, Lisa; Rao, Abhi; Vaught, Jim; Greenman, Howard; McLean, Jeffrey; Reed, Daniel; Memon, Sarfraz; Fombonne, Benjamin; Guan, Ping
2015-01-01
Background: Biospecimens are essential resources for advancing basic and translational research. However, there are little data available regarding the costs associated with operating a biobank, and few resources to enable their long-term sustainability. To support the research community in this effort, the National Institutes of Health, National Cancer Institute's Biorepositories and Biospecimen Research Branch has developed the Biobank Economic Modeling Tool (BEMT). The tool is accessible at http://biospecimens.cancer.gov/resources/bemt.asp. Methods: To obtain market-based cost information and to inform the development of the tool, a survey was designed and sent to 423 biobank managers and directors across the world. The survey contained questions regarding infrastructure investments, salary costs, funding options, types of biospecimen resources and services offered, as well as biospecimen pricing and service-related costs. Results: A total of 106 responses were received. The data were anonymized, aggregated, and used to create a comprehensive database of cost and pricing information that was integrated into the web-based tool, the BEMT. The BEMT was built to allow the user to input cost and pricing data through a seven-step process to build a cost profile for their biobank, define direct and indirect costs, determine cost recovery fees, perform financial forecasting, and query the anonymized survey data from comparable biobanks. Conclusion: A survey was conducted to obtain a greater understanding of the costs involved in operating a biobank. The anonymized survey data was then used to develop the BEMT, a cost modeling tool for biobanks. Users of the tool will be able to create a cost profile for their biobanks' specimens, products and services, establish pricing, and allocate costs for biospecimens based on percent cost recovered, and perform project-specific cost analyses and financial forecasting. PMID:26697911
Odeh, Hana; Miranda, Lisa; Rao, Abhi; Vaught, Jim; Greenman, Howard; McLean, Jeffrey; Reed, Daniel; Memon, Sarfraz; Fombonne, Benjamin; Guan, Ping; Moore, Helen M
2015-12-01
Biospecimens are essential resources for advancing basic and translational research. However, there are little data available regarding the costs associated with operating a biobank, and few resources to enable their long-term sustainability. To support the research community in this effort, the National Institutes of Health, National Cancer Institute's Biorepositories and Biospecimen Research Branch has developed the Biobank Economic Modeling Tool (BEMT). The tool is accessible at http://biospecimens.cancer.gov/resources/bemt.asp. To obtain market-based cost information and to inform the development of the tool, a survey was designed and sent to 423 biobank managers and directors across the world. The survey contained questions regarding infrastructure investments, salary costs, funding options, types of biospecimen resources and services offered, as well as biospecimen pricing and service-related costs. A total of 106 responses were received. The data were anonymized, aggregated, and used to create a comprehensive database of cost and pricing information that was integrated into the web-based tool, the BEMT. The BEMT was built to allow the user to input cost and pricing data through a seven-step process to build a cost profile for their biobank, define direct and indirect costs, determine cost recovery fees, perform financial forecasting, and query the anonymized survey data from comparable biobanks. A survey was conducted to obtain a greater understanding of the costs involved in operating a biobank. The anonymized survey data was then used to develop the BEMT, a cost modeling tool for biobanks. Users of the tool will be able to create a cost profile for their biobanks' specimens, products and services, establish pricing, and allocate costs for biospecimens based on percent cost recovered, and perform project-specific cost analyses and financial forecasting.
Software Engineering Research/Developer Collaborations (C104)
NASA Technical Reports Server (NTRS)
Shell, Elaine; Shull, Forrest
2005-01-01
The goal of this collaboration was to produce Flight Software Branch (FSB) process standards for software inspections which could be used across three new missions within the FSB. The standard was developed by Dr. Forrest Shull (Fraunhofer Center for Experimental Software Engineering, Maryland) using the Perspective-Based Inspection approach, (PBI research has been funded by SARP) , then tested on a pilot Branch project. Because the short time scale of the collaboration ruled out a quantitative evaluation, it would be decided whether the standard was suitable for roll-out to other Branch projects based on a qualitative measure: whether the standard received high ratings from Branch personnel as to usability and overall satisfaction. The project used for piloting the Perspective-Based Inspection approach was a multi-mission framework designed for reuse. This was a good choice because key representatives from the three new missions would be involved in the inspections. The perspective-based approach was applied to produce inspection procedures tailored for the specific quality needs of the branch. The technical information to do so was largely drawn through a series of interviews with Branch personnel. The framework team used the procedures to review requirements. The inspections were useful for indicating that a restructuring of the requirements document was needed, which led to changes in the development project plan. The standard was sent out to other Branch personnel for review. Branch personnel were very positive. However, important changes were identified because the perspective of Attitude Control System (ACS) developers had not been adequately represented, a result of the specific personnel interviewed. The net result is that with some further work to incorporate the ACS perspective, and in synchrony with the roll out of independent Branch standards, the PBI approach will be implemented in the FSB. Also, the project intends to continue its collaboration with the technology provider (Dr. Forrest Shull) past the end of the grant, to allow a more rigorous quantitative evaluation.
Fort Collins Science Center: Species and Habitats of Federal Interest
Stevens, Patty
2004-01-01
Ecosystem changes directly affect a wide variety of plant and animal species, floral and faunal communities, and groups of species such as amphibians and grassland birds. Appropriate management of public lands plays a crucial role in the conservation and recovery of endangered species and can be a key element in preventing a species from being listed under the Endangered Species Act. The Species and Habitats of Federal Interest Branch of the Fort Collins Science Center (FORT) conducts research on the ecology, habitat requirements, distribution and abundance, population dynamics, and genetics and systematics of many species facing threatened or endangered status or of special concern to resource management agencies. FORT scientists develop reintroduction and restoration techniques, technologies for monitoring populations, and novel methods to analyze data on population trends and habitat requirements. FORT expertise encompasses both traditional and specialized natural resource disciplines within wildlife biology, including population dynamics, animal behavior, plant and community ecology, inventory and monitoring, statistics and computer applications, conservation genetics, stable isotope analysis, and curatorial expertise.
A cooperative study of gate entry designs: Welbeck Colliery (UK) and Jim Walter Resources (USA)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hendon, G.; Carr, F.; Lewis, A.
1995-11-01
Longwall developments in the UK have historically consisted of single entry gate roads. Adjacent developments were separated from existing pales by large barrier pillars (designed of sufficient width to get away from the longwall abutments of the previous panel) or by small barriers driven in the shadow, or de-stressed zone, of the previous panel. Some 2nd panel tailgates were also driven skin to skin leaving no coal barrier between the newly driven entry and the heavily supported existing gateroad. With the development and wide acceptance of fully bolted entries and the pressure to reduce production costs, alternatives to single entrymore » drivage, particularly yield pillar developments, were examined. Through the Rock Mechanics Branch of british Coal, a cooperative study was begun with Jim Walter Resources, Inc., USA, (JWR) to look at the yield pillar alternative in detail. This study was to determine the feasibility of utilizing yield pillars in the UK and to determine, through monitoring, the possibility of reducing stable pillar widths at JWR. The study has included extensive monitoring of the yield-stable-yield pillar system at JWR No. 7 Mine and an underground trial of a two entry yield pillar test area at Welbeck Colliery in the UK. This paper describes results from the JWR study and the subsequent results of the first advancing yield pillar development in the UK at Welbeck Colliery.« less
NASA Astrophysics Data System (ADS)
Trottier, Olivier; Ganguly, Sujoy; Bowne-Anderson, Hugo; Liang, Xin; Howard, Jonathon
For the last 120 years, the development of neuronal shapes has been of great interest to the scientific community. Over the last 30 years, significant work has been done on the molecular processes responsible for dendritic development. In our ongoing research, we use the class IV sensory neurons of the Drosophila melanogaster larva as a model system to understand the growth of dendritic arbors. Our main goal is to elucidate the mechanisms that the neuron uses to determine the shape of its dendritic tree. We have observed the development of the class IV neuron's dendritic tree in the larval stage and have concluded that morphogenesis is defined by 3 distinct processes: 1) branch growth, 2) branching and 3) branch retraction. As the first step towards understanding dendritic growth, we have implemented these three processes in a computational model. Our simulations are able to reproduce the branch length distribution, number of branches and fractal dimension of the class IV neurons for a small range of parameters.
Universe Awareness: a global educational programme
NASA Astrophysics Data System (ADS)
Sankatsing Nava, Tibisay; Russo, Pedro
2015-08-01
Universe Awareness (UNAWE) is a global astronomy education programme that uses the beauty and grandeur of the Universe to encourage young children, particularly those from an underprivileged background, to have an interest in science and technology and foster their sense of global citizenship from an early age.UNAWE’s activities consist of four main components:- Coordinating an international network comprised of more than 1000 astronomers, teachers and educators in more than 60 countries- Developing and distributing educational resources such as the inflatable UNAWE Earthball, the Universe-in-a Box educational kit and Space Scoop, the astronomy news service for children.- Providing training activities for teachers and other educators of young children around the world- Providing resources for the evaluation of educational activitiesBetween 2011 and 2013, the European branch of UNAWE, EU-UNAWE, was funded by the European Commission to implement a project in 5 EU countries and South Africa. This project has been concluded successfully. The global project of Universe Awareness coordinated by Leiden University has continued to grow since, with an expanding international network, new educational resources and teacher trainings and an International Workshop in collaboration with ESA in October 2015, among other activities.
Convex Relaxation of OPF in Multiphase Radial Networks with Wye and Delta Connections
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhao, Changhong; Dall-Anese, Emiliano; Low, Steven
2017-08-01
This panel presentation focuses on multiphase radial distribution networks with wye and delta connections, and proposes a semidefinite relaxation of the AC optimal power flow (OPF) problem. Two multiphase power flow models are developed to facilitate the integration of delta-connected loads or generation resources in the OPF problem. The first model is referred to as the extended branch flow model (EBFM). The second model leverages a linear relationship between phase-to-ground power injections and delta connections that holds under a balanced voltage approximation (BVA). Based on these models, pertinent OPF problems are formulated and relaxed to semidefinite programs (SDPs). Numerical studiesmore » on IEEE test feeders show that the proposed SDP relaxations can be solved efficiently by a generic optimization solver. Numerical evidence also indicates that solving the resultant SDP under BVA is faster than under EBFM. Moreover, both SDP solutions are numerically exact with respect to voltages and branch flows. It is further shown that the SDP solution under BVA has a small optimality gap, and the BVA model is accurate in the sense that it reproduces actual system voltages.« less
Puanglek, Sakarin; Kimura, Satoshi; Enomoto-Rogers, Yukiko; Kabe, Taizo; Yoshida, Makoto; Wada, Masahisa; Iwata, Tadahisa
2016-01-01
Bio-based polymer is considered as one of potentially renewable materials to reduce the consumption of petroleum resources. We report herein on the one-pot synthesis and development of unnatural-type bio-based polysaccharide, α-1,3-glucan. The synthesis can be achieved by in vitro enzymatic polymerization with GtfJ enzyme, one type of glucosyltransferase, cloned from Streptococcus salivarius ATCC 25975 utilizing sucrose, a renewable feedstock, as a glucose monomer source, via environmentally friendly one-pot water-based reaction. The structure of α-1,3-glucan is completely linear without branches with weight-average molecular weight (Mw) of 700 kDa. Furthermore, acetate and propionate esters of α-1,3-glucan were synthesized and characterized. Interestingly, α-1,3-glucan acetate showed a comparatively high melting temperature at 339 °C, higher than that of commercially available thermoplastics such as PET (265 °C) and Nylon 6 (220 °C). Thus, the discovery of crystalline α-1,3-glucan esters without branches with high thermal stability and melting temperature opens the gate for further researches in the application of thermoplastic materials. PMID:27469976
Basic data from five core holes in the Raft River geothermal area, Cassia County, Idaho
Crosthwaite, E. G.
1976-01-01
meters) were completed in the area (Crosthwaite, 1974), and the Aerojet Nuclear Company, under the auspices of the U.S. Energy Research and Development Administration, was planning some deep drilling 4,000 to 6,000 feet (1,200 to 1,800 meters) (fig. 1). The purpose of the core drilling was to provide information to test geophysical interpretations of the subsurface structure and lithology and to provide hydrologic and geologic data on the shallow part of the geothermal system. Samples of the core were made available to several divisions and branches of the Geological Survey and to people and agencies outside the Survey. This report presents the basic data from the core holes that had been collected to September 1, 1975, and includes lithologic and geophysical well logs, chemical analyses of water (table 1), and laboratory analyses of cores (table 2) that were completed as of the above date. The data were collected by the Idaho District office, Hydrologic Laboratory, Borehole Geophysics Research Project, and Drilling, Sampling, and Testing Section, all of the Water Resources Division, and the Branch of Central Environmental Geology of the Geologic Divison.
NASA Astrophysics Data System (ADS)
Puanglek, Sakarin; Kimura, Satoshi; Enomoto-Rogers, Yukiko; Kabe, Taizo; Yoshida, Makoto; Wada, Masahisa; Iwata, Tadahisa
2016-07-01
Bio-based polymer is considered as one of potentially renewable materials to reduce the consumption of petroleum resources. We report herein on the one-pot synthesis and development of unnatural-type bio-based polysaccharide, α-1,3-glucan. The synthesis can be achieved by in vitro enzymatic polymerization with GtfJ enzyme, one type of glucosyltransferase, cloned from Streptococcus salivarius ATCC 25975 utilizing sucrose, a renewable feedstock, as a glucose monomer source, via environmentally friendly one-pot water-based reaction. The structure of α-1,3-glucan is completely linear without branches with weight-average molecular weight (Mw) of 700 kDa. Furthermore, acetate and propionate esters of α-1,3-glucan were synthesized and characterized. Interestingly, α-1,3-glucan acetate showed a comparatively high melting temperature at 339 °C, higher than that of commercially available thermoplastics such as PET (265 °C) and Nylon 6 (220 °C). Thus, the discovery of crystalline α-1,3-glucan esters without branches with high thermal stability and melting temperature opens the gate for further researches in the application of thermoplastic materials.
Hamberg, Leena; Velmala, Sannakajsa M; Sievänen, Risto; Kalliokoski, Tuomo; Pennanen, Taina
2018-06-01
The relationship between the growth rate of aboveground parts of trees and fine root development is largely unknown. We investigated the early root development of fast- and slow-growing Norway spruce (Picea abies (L.) H. Karst.) families at a developmental stage when the difference in size is not yet observed. Seedling root architecture data, describing root branching, were collected with the WinRHIZO™ image analysis system, and mixed models were used to determine possible differences between the two growth phenotypes. A new approach was used to investigate the spatial extent of root properties along the whole sample root from the base of 1-year-old seedlings to the most distal part of a root. The root architecture of seedlings representing fast-growing phenotypes showed ~30% higher numbers of root branches and tips, which resulted in larger root extensions and potentially a better ability to acquire nutrients. Seedlings of fast-growing phenotypes oriented and allocated root tips and biomass further away from the base of the seedling than those growing slowly, a possible advantage in nutrient-limited and heterogeneous boreal forest soils. We conclude that a higher long-term growth rate of the aboveground parts in Norway spruce may relate to greater allocation of resources to explorative roots that confers a competitive edge during early growth phases in forest ecosystems.
Technology transfer program: Perspective
NASA Technical Reports Server (NTRS)
Toyshov, A. J.
1981-01-01
Most of NASA's technology transfer activities are in the area of land use (development, suitability, and planning); forestry (including wildlife and range and vegetation inventories) agriculture related activities; and water resources. The technology dissemination function is exercised through three regional applications centers which are involved in 91 applications projects within 22 states. In addition there are approximately eight application system verification transfer (ASVT) projects, 21 university applications branches, institutionalized liason activities with public interest groups, and user requirements activities. As the result of budget cuts, the ASVT and user requirements and awareness programs are to be phased out at the end of FY81. The university applications programs are to be phased down and terminated by 1985. NASA will continue to work with the user more in an R & D and an applications development capacity, and not in a national scale or administrative way.
CADD Modeling of Multi-Target Drugs Against Alzheimer's Disease.
Ambure, Pravin; Roy, Kunal
2017-01-01
Alzheimer's disease (AD) is a neurodegenerative disorder that is described by multiple factors linked with the progression of the disease. The currently approved drugs in the market are not capable of curing AD; instead, they merely provide symptomatic relief. Development of multi-target directed ligands (MTDLs) is an emerging strategy for improving the quality of the treatment against complex diseases like AD. Polypharmacology is a branch of pharmaceutical sciences that deals with the MTDL development. In this mini-review, we have summarized and discussed different strategies that are reported in the literature to design MTDLs for AD. Further, we have discussed the role of different in silico techniques and online resources in computer-aided drug discovery (CADD), for designing or identifying MTDLs against AD. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
Wei, Dacheng; Liu, Yunqi; Cao, Lingchao; Fu, Lei; Li, Xianglong; Wang, Yu; Yu, Gui; Zhu, Daoben
2006-02-01
Here we develop a simple method by using flow fluctuation to synthesize arrays of multi-branched carbon nanotubes (CNTs) that are far more complex than those previously reported. The architectures and compositions can be well controlled, thus avoiding any template or additive. A branching mechanism of fluctuation-promoted coalescence of catalyst particles is proposed. This finding will provide a hopeful approach to the goal of CNT-based integrated circuits and be valuable for applying branched junctions in nanoelectronics and producing branched junctions of other materials.
Ferris, John G.
1950-01-01
This memorandum summarize information brought out in correspondence between the office of the District Engineer of the Milwaukee District, U.S. Corps of Engineers, and the District Office of the Ground Water Branch of the U.S. Geological Survey at Lansing, Mich., concerning the probable effects on the ground-water resources of the Lansing area from the construction of a proposed flood-water cut-off channel for the Grand River to extend from Millett to Delta Mills, in Eaton County, Mich.
1983-02-01
Arnica -- herb with yellow flowers made into tincture and used as stimulant and curative for bruises and sprains) Now extinct. GH Arthur (Vernon) Village...Bedford • lost influence, renamed Handley. WHA, NHl Bee Branch (Henry) A tributary of Big Creek in the NW Big Creek T. S named for the wild bees so...T. named for its location amid many wild cherry trees. SSR Cherry Grove School (Bates) For flora. SSR S S 0 S 43 0 Cherry Valley School (Cedar) For
NASA Astrophysics Data System (ADS)
Lamorski, Krzysztof; Šimūnek, Jiří; Sławiński, Cezary; Lamorska, Joanna
2017-02-01
In this paper, we estimated using the machine learning methodology the main wetting branch of the soil water retention curve based on the knowledge of the main drying branch and other, optional, basic soil characteristics (particle size distribution, bulk density, organic matter content, or soil specific surface). The support vector machine algorithm was used for the models' development. The data needed by this algorithm for model training and validation consisted of 104 different undisturbed soil core samples collected from the topsoil layer (A horizon) of different soil profiles in Poland. The main wetting and drying branches of SWRC, as well as other basic soil physical characteristics, were determined for all soil samples. Models relying on different sets of input parameters were developed and validated. The analysis showed that taking into account other input parameters (i.e., particle size distribution, bulk density, organic matter content, or soil specific surface) than information about the drying branch of the SWRC has essentially no impact on the models' estimations. Developed models are validated and compared with well-known models that can be used for the same purpose, such as the Mualem (1977) (M77) and Kool and Parker (1987) (KP87) models. The developed models estimate the main wetting SWRC branch with estimation errors (RMSE = 0.018 m3/m3) that are significantly lower than those for the M77 (RMSE = 0.025 m3/m3) or KP87 (RMSE = 0. 047 m3/m3) models.
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1995-08-01
This Readiness Assessment Plan has been prepared to document operational readiness for the following maintenance action: (1) removal of sediment from the White Oak Creek and Melton Branch Weir Stilling Pools and (2) disposal of the radiologically contaminated sediment in another location upstream of the weirs in an area previously contaminated by stream overflow from Melton Branch in Waste Area Grouping 2 (WAG) at Oak Ridge National Laboratory. This project is being performed as a maintenance action rather than an action under the Comprehensive Environmental Response, Compensation, and Liability Act because the risk to human health and environment is wellmore » below the US Environmental Protection Agency`s level of concern. The decision to proceed as a maintenance action was documented by an interim action proposed plan, which is included in the administrative record. The administrative record is available for review at the US Department of Energy Information Resource Center, 105 Broadway Avenue, Oak Ridge, Tennessee 37830.« less
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-14
... for Employment Information in Connection With Claim for Disability Benefits) Activity Under OMB Review....Regulations.gov or to VA's OMB Desk Officer, OMB Human Resources and Housing Branch, New Executive Office... INFORMATION: Title: Request for Employment Information in Connection with Claim for Disability Benefits, VA...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-31
... to Employer for Employment Information in Connection With Claim for Disability Benefits) Activities... through http://www.Regulations.gov or to VA's OMB Desk Officer, OMB Human Resources and Housing Branch... Connection with Claim for Disability Benefits, VA Form Letter 29-459. OMB Control Number: 2900-0066. Type of...
National Drug Control Strategy. FY 2009 Budget Summary
ERIC Educational Resources Information Center
The White House, 2008
2008-01-01
The National Drug Control Budget Summary identifies resources and performance indicators for programs within the Executive Branch that are integral to the President's National Drug Control Strategy. The Strategy, which is the Administration's plan for reducing drug use and availability, is based on three pillars: (1) Stopping Use Before It Starts,…
Resources for Renewal: Liberal Education for Work and Leisure.
ERIC Educational Resources Information Center
Reagin, Ewell J.
A cooperative project of Warren Wilson College, North Carolina, the College for Human Services, New York, and Merrimack Valley Branch/University of New Hampshire on the topic of leisure and liberal education is described. The project is part of "Change in Liberal Education," a network concerned with the renewal of liberal education. The…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-13
....Regulations.gov ; or to VA's OMB Desk Officer, OMB Human Resources and Housing Branch, New Executive Office...' Group Life Insurance (SGLI) or Veterans' Group Life Insurance (VGLI) prior to death. If the insured...' Group Life Insurance Accelerated Benefits Option application. The application must include a medical...
12 CFR 28.12 - Approval of a Federal branch or agency.
Code of Federal Regulations, 2010 CFR
2010-01-01
..., the OCC considers: (1) The financial and managerial resources and future prospects of the applicant... operations of the foreign bank to assess the foreign bank's overall financial condition and compliance with... consolidation with, a foreign bank that has an office in the United States, may proceed with the transaction...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-02
... Alternative. Natural, cultural, and socioeconomic resource impacts associated with the implementation of the..., please contact: Richard A. Cohn, Chief, or Issac J. Gaston, Site Selection Specialist, Capacity Planning and Site Selection Branch, Federal Bureau of Prisons, 320 First Street, NW., Washington, DC 20534 Tel...
Neuro-Oncology Branch patient education | Center for Cancer Research
Patient Education We want to ensure that our patients are well informed. To help answer some of the questions you may have, visit the resources listed below. National Cancer Institute (NCI) NCI is the Federal Government’s principal agency for cancer research and training. As part of its mission, NCI provides information on cancer.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-14
... Officer, OMB Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC... Management and Budget (OMB) for review and comment. The PRA submission describes the nature of the.... Type of Review: Extension of a currently approved collection. Abstract: Employers providing on-job or...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-17
... Officer, OMB Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC... Certification of On-the- Job and Apprenticeship Training): Activity Under OMB Review AGENCY: Veterans Benefits... abstracted below to the Office of Management and Budget (OMB) for review and comment. The PRA submission...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-10
..., OMB Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC... (Agreement To Train on the Job Disabled Veterans): Activity Under OMB Review AGENCY: Veterans Benefits... to the Office of Management and Budget (OMB) for review and comment. The PRA submission describes the...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-27
... Office of Management and Budget (OMB) for review and comment. The PRA submission describes the nature of... on the collection of information through www.Regulations.gov or to VA's OMB Desk Officer, OMB Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC 20503 (202) 395-7316...
ERIC Educational Resources Information Center
Paulk, J. Sara
2009-01-01
Over the past year, libraries have made the national news owing to soaring public usage driven by tough economic times. Much of this increased traffic stems from patrons coming to their local branches to use resources that will help them improve their chances at employment. While some demand practical job-hunting and career materials to help them…
76 FR 9358 - Notice of Proposed Withdrawal Extension and Opportunity for Public Meeting; Montana
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-17
... DEPARTMENT OF THE INTERIOR Bureau of Land Management [MTM 067221] Notice of Proposed Withdrawal Extension and Opportunity for Public Meeting; Montana AGENCY: Bureau of Land Management, Interior. ACTION.... Cynthia Staszak, Chief, Branch of Land Resources. [FR Doc. 2011-3617 Filed 2-16-11; 8:45 am] BILLING CODE...
2010-09-01
DEVELOPMENT TESTING BEING CONDUCTED AT THE REQUEST OF THE MSFC DYNAMICS, LOADS, AND STRENGTH BRANCH (EV31) TO STUDY THE FAILURE BEHAVIOR OF FASTENERS SUBJECTED TO COMBINED SHEAR AND TENSION LOADING. THE DATA FROM THIS TESTING WILL BE USED TO DEVELOP APPROPRIATE STRUCTURAL ANALYSIS METHODS AS PART OF A FASTENER STANDARDS EFFORT SPONSORED BY THE NASA ENGINEERING SAFETY CENTER (NESC). THE TEST FIXTURE WAS DESIGNED AND FABRICATED THROUGH THE MSFC MECHANICAL FABRICATION BRANCH (ES23). THE TESTING ORGANIZATION IS THE MSFC MATERIALS TEST BRANCH (EM10).
2010-09-01
DEVELOPMENT TESTING BEING CONDUCTED AT THE REQUEST OF THE MSFC DYNAMICS, LOADS, AND STRENGTH BRANCH (EV31) TO STUDY THE FAILURE BEHAVIOR OF FASTENERS SUBJECTED TO COMBINED SHEAR AND TENSION LOADING. THE DATA FROM THIS TESTING WILL BE USED TO DEVELOP APPROPRIATE STRUCTURAL ANALYSIS METHODS AS PART OF A FASTENER STANDARDS EFFORT SPONSORED BY THE NASA ENGINEERING SAFETY CENTER (NESC). THE TEST FIXTURE WAS DESIGNED AND FABRICATED THROUGH THE MSFC MECHANICAL FABRICATION BRANCH (ES23). THE TESTING ORGANIZATION IS THE MSFC MATERIALS TEST BRANCH (EM10).
2010-09-01
DEVELOPMENT TESTING BEING CONDUCTED AT THE REQUEST OF THE MSFC DYNAMICS, LOADS, AND STRENGTH BRANCH (EV31) TO STUDY THE FAILURE BEHAVIOR OF FASTENERS SUBJECTED TO COMBINED SHEAR AND TENSION LOADING. THE DATA FROM THIS TESTING WILL BE USED TO DEVELOP APPROPRIATE STRUCTURAL ANALYSIS METHODS AS PART OF A FASTENER STANDARDS EFFORT SPONSORED BY THE NASA ENGINEERING SAFETY CENTER (NESC). THE TEST FIXTURE WAS DESIGNED AND FABRICATED THROUGH THE MSFC MECHANICAL FABRICATION BRANCH (ES23). THE TESTING ORGANIZATION IS THE MSFC MATERIALS TEST BRANCH (EM10).
2010-09-01
DEVELOPMENT TESTING BEING CONDUCTED AT THE REQUEST OF THE MSFC DYNAMICS, LOADS, AND STRENGTH BRANCH (EV31) TO STUDY THE FAILURE BEHAVIOR OF FASTENERS SUBJECTED TO COMBINED SHEAR AND TENSION LOADING. THE DATA FROM THIS TESTING WILL BE USED TO DEVELOP APPROPRIATE STRUCTURAL ANALYSIS METHODS AS PART OF A FASTENER STANDARDS EFFORT SPONSORED BY THE NASA ENGINEERING SAFETY CENTER (NESC). THE TEST FIXTURE WAS DESIGNED AND FABRICATED THROUGH THE MSFC MECHANICAL FABRICATION BRANCH (ES23). THE TESTING ORGANIZATION IS THE MSFC MATERIALS TEST BRANCH (EM10).
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-16
...: (404) 562-9019. 4. Mail: ``EPA-R04-OAR-2011-0867,'' Regulatory Development Section, Air Planning Branch..., Regulatory Development Section, Air Planning Branch, Air, Pesticides and Toxics Management Division, U.S....regulations.gov or in hard copy at the Regulatory Development Section, [[Page 78163
Virtual Control Policy for Binary Ordered Resources Petri Net Class.
Rovetto, Carlos A; Concepción, Tomás J; Cano, Elia Esther
2016-08-18
Prevention and avoidance of deadlocks in sensor networks that use the wormhole routing algorithm is an active research domain. There are diverse control policies that will address this problem being our approach a new method. In this paper we present a virtual control policy for the new specialized Petri net subclass called Binary Ordered Resources Petri Net (BORPN). Essentially, it is an ordinary class constructed from various state machines that share unitary resources in a complex form, which allows branching and joining of processes. The reduced structure of this new class gives advantages that allow analysis of the entire system's behavior, which is a prohibitive task for large systems because of the complexity and routing algorithms.
Field and office instructions in stream gauging for the Hydrological Survey of Zambia
Bidwell, L.E.
1971-01-01
The importance of water to the basic needs of man is self- evident and needs no particular emphasis. The importance of water to a developing economy cannot be overemphasized. A few decades ago, hydrology was a division of hydraulic engineering and was a tool for project survey, plan, and design. Today hydrology still remains an important part of planning and management of water use projects, but it is imperative that surface and ground-water basic data networks be designed and operated from the standpoint of both present and future water needs. Water problems are ever increasing and ever changing and preparation for the future water demands of Zambia requires knowledge of the hydrology of the country instead of the examination of piecemeal samples for each water use project. The hydrologic survey of Zambia needs to be under the guidance of competent and imaginative hydrologists solidly trained in all elements of basic data collection and analysis and not in the hands of water project planners. Hydrology is a science which requires the highest order of teamwork and the hydrologist will need the help and advice of many employees within the organization to operate the network, provide adequate research, and examine the water needs of the country. It must be thoroughly understood that communication is essential between the hydrological survey and water project planners from both the government and private sectors. It is very important to define the aims and duties of the Hydrological Branch of the Water Affairs Department in a clear cut "Statement of Policy". Personal copies of the statement should be made available to all professional employees and technicians. The reasons for the existence of the Branch may be self-apparent to heads of the organization, but to all other employees the reasons may be vague and unknown. Every member of the technical and administrative staff would benefit by an understanding of the purpose of his work. Nebulous ideas of the function of a hydrological survey of Zambia serve little purpose to the employee making the plans or those who execute them. A dissemination and free flow of ideas in all directions is necessary in any scientific and creative organization. The primary functions of the Hydrological Branch of the Water Affairs Department of Zambia are twofold: Water resource appraisal which includes the inventory of all surface and ground waters;Research, both basic and applied, in the science of water.Possibly some function regarding water law is also conceivable, although attachment of a law enforcement function to water-resource investigations might weaken the position of the Branch as an unbiased scientific organization.As the collection of basic streamflow data is a primary function of the Branch the following instructions for the collection, analysis and computation of streamflow records have been written.
Hydrologic and hydraulic analyses at Akin Branch and Cayce Valley Branch, Columbia, Tennessee
Outlaw, George S.
1993-01-01
The U.S. Geological Survey, in cooperation with the City of Columbia, Tennessee, conducted hydrologic and hydraulic analyses at Akin Branch and Cayce Valley Branch in the Little Bigby Creek watershed, Columbia, Tennessee, from 1990 through 1991. Results of the analyses can be used by city planners in the development of plans to replace several deteriorating and inadequate drainage structures. Akin Branch and Cayce Valley Branch drain small watersheds of 1.69 and 1.04 square miles, respectively. Flood discharges for 5-, lo-, and 25-year recurrence-interval storm events were calculated at the stream mouths using flood-frequency relations developed for use at small urban streams in Tennessee. For each stream, flood discharges at locations upstream from the mouth were calculated by subdividing the watershed and assigning a percentage of the discharge at the mouth, based on drainage area, to each subarea. Flood profiles for the selected recurrence-interval flood discharges were simulated for Akin Branch and Cayce Valley Branch for existing conditions and conditions that might exist if drainage improvements such as larger culverts and bridges and channel improvements are constructed. The results of the simulations were used to predict changes in flood elevations that might result from such drainage improvements. Analyses indicate that reductions in existing flood elevations of as much as 2.1 feet for the 5-year flood at some sites on Akin Branch and as much as 3.8 feet for the 5-year flood at some sites on Cayce Valley Branch might be expected with the drainage improvements.
Harry T. Valentine
2002-01-01
Randomized branch sampling (RBS) is a special application of multistage probability sampling (see Sampling, environmental), which was developed originally by Jessen [3] to estimate fruit counts on individual orchard trees. In general, the method can be used to obtain estimates of many different attributes of trees or other branched plants. The usual objective of RBS is...
Gervais, Louis; Casanova, Jordi
2011-04-01
Recent data have demonstrated a crucial role for the transcription factor SRF (serum response factor) downstream of VEGF and FGF signalling during branching morphogenesis. This is the case for sprouting angiogenesis in vertebrates, axonal branching in mammals and terminal branching of the Drosophila tracheal system. However, the specific functions of SRF in these processes remain unclear. Here, we establish the relative contributions of the Drosophila homologues of FGF [Branchless (BNL)] and SRF [Blistered (BS)] in terminal tracheal branching. Conversely to an extended view, we show that BNL triggers terminal branching initiation in a DSRF-independent mechanism and that DSRF transcription induced by BNL signalling is required to maintain terminal branch elongation. Moreover, we report that increased and continuous FGF signalling can trigger tracheal cells to develop full-length terminal branches in the absence of DSRF transcription. Our results indicate that DSRF acts as an amplifying step to sustain the progression of terminal branch elongation even in the wild-type conditions of FGF signalling.
Zhao, Zhen; Wang, Zheng; Gu, Ying; Feil, Robert; Hofmann, Franz; Ma, Le
2009-02-04
Cyclic GMP has been proposed to regulate axonal development, but the molecular and cellular mechanisms underlying the formation of axon branches are not well understood. Here, we report the use of rodent embryonic sensory neurons from the dorsal root ganglion (DRG) to demonstrate the role of cGMP signaling in axon branching and to identify the downstream molecular pathway mediating this novel regulation. Pharmacologically, a specific cGMP analog promotes DRG axon branching in culture, and this activity can be achieved by activating the endogenous soluble guanylyl cyclase that produces cGMP. At the molecular level, the cGMP-dependent protein kinase 1 (PrkG1) mediates this activity, as DRG neurons isolated from the kinase-deficient mouse fail to respond to cGMP activation to make branches, whereas overexpression of a PrkG1 mutant with a higher-than-normal basal kinase activity is sufficient to induce branching. In addition, cGMP activation in DRG neurons leads to phosphorylation of glycogen synthase kinase 3 (GSK3), a protein that normally suppresses branching. This interaction is direct, because PrkG1 binds GSK3 in heterologous cells and the purified kinase can phosphorylate GSK3 in vitro. More importantly, overexpression of a dominant active form of GSK3 suppresses cGMP-dependent branching in DRG neurons. Thus, our study establishes an intrinsic signaling cascade that links cGMP activation to GSK3 inhibition in controlling axon branching during sensory axon development.
75 FR 70044 - Withdrawal of Regulatory Guide 1.39
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-16
...: Hector L. Rodriguez-Luccioni, Regulatory Guide Development Branch, Division of Engineering, Office of...-251-7685 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I. Introduction The... N. Ridgely, Acting Chief, Regulatory Guide Development Branch, Division of Engineering, Office of...
Modeling the growth and branching of plants: A simple rod-based model
NASA Astrophysics Data System (ADS)
Faruk Senan, Nur Adila; O'Reilly, Oliver M.; Tresierras, Timothy N.
A rod-based model for plant growth and branching is developed in this paper. Specifically, Euler's theory of the elastica is modified to accommodate growth and remodeling. In addition, branching is characterized using a configuration force and evolution equations are postulated for the flexural stiffness and intrinsic curvature. The theory is illustrated with examples of multiple static equilibria of a branched plant and the remodeling and tip growth of a plant stem under gravitational loading.
Application of ERTS-1 data to the protection and management of New Jersey's coastal environment
NASA Technical Reports Server (NTRS)
Mairs, R. L.; Wobber, F. J.; Garofalo, D.; Yunghans, R. S.
1973-01-01
ERTS-1 imagery is being used by the New Jersey Department of Environmental Protection (NJDEP) to develop information products that will assist the state in optimally managing its coastal resources and in allocating funds. Interviews with NJDEP personnel have identified significant problem areas in the coastal zone, and the types of remote sensor derived information products that can be used in real-time decision making. Initial analyses of imagery from several successive ERTS-1 orbits have shown the extent, predominant drift, and dispersion characteristics of waste disposal in coastal New Jersey waters. Imagery (MSS Bands 4 and 5) for several orbits, shows that New-York Harbor tidal discharge extending as far south as Long Branch, New Jersey.
25 Years of Cell Cycle Research: What's Ahead?
Gutierrez, Crisanto
2016-10-01
We have reached 25 years since the first molecular approaches to plant cell cycle. Fortunately, we have witnessed an enormous advance in this field that has benefited from using complementary approaches including molecular, cellular, genetic and genomic resources. These studies have also branched and demonstrated the functional relevance of cell cycle regulators for virtually every aspect of plant life. The question is - where are we heading? I review here the latest developments in the field and briefly elaborate on how new technological advances should contribute to novel approaches that will benefit the plant cell cycle field. Understanding how the cell division cycle is integrated at the organismal level is perhaps one of the major challenges. Copyright © 2016 Elsevier Ltd. All rights reserved.
Regulation of lung branching morphogenesis by bombesin-like peptides and neutral endopeptidase.
Aguayo, S M; Schuyler, W E; Murtagh, J J; Roman, J
1994-06-01
The expression of bombesin-like peptides (BLPs) by pulmonary neuroendocrine cells is transiently upregulated during lung development. A functional role for BLPs is supported by their ability to stimulate lung growth and maturation both in vitro and in vivo during the late stages of lung development. In addition, the cell membrane-associated enzyme CD10/neutral endopeptidase 24.11 (CD10/NEP), which inactivates BLPs and other regulatory peptides, is also expressed by developing lungs and modulates the stimulatory effects of BLPs on lung growth and maturation. We hypothesized that, in addition to expressing BLPs and CD10/NEP, embryonic lungs must express BLP receptors, and that BLPs may also regulate processes that occur during early lung development such as branching morphogenesis. Using reverse transcriptase-polymerase chain reaction and oligonucleotide primers designed for amplifying a BLP receptor originally isolated from Swiss 3T3 mouse fibroblasts, we found that embryonic mouse lungs express a similar BLP receptor mRNA during the pseudoglandular stage of lung development when branching morphogenesis take place. Subsequently, we evaluated the effects of ligands for this BLP receptor using embryonic mouse lungs in an in vitro model of lung branching morphogenesis. We found that, in comparison with control lungs, treatment with bombesin (1 to 100 nM) resulted in a modest increase in clefts or branching points. In contrast, embryonic mouse lungs treated with the BLP analog [Leu13-psi(CH2NH)Leu14]bombesin (1 microM), which also binds to this BLP receptor but has predominantly antagonistic effects, demonstrated fewer branching points.(ABSTRACT TRUNCATED AT 250 WORDS)
Clinical and Translational Epidemiology Branch (CTEB)
The Clinical and Translational Epidemiology Branch focuses on factors that influence cancer progression, recurrence, survival, and other treatment outcomes, and factors associated with cancer development.
Steuer, Jeffrey J.; Hunt, R.J.
2001-01-01
The North Fork Pheasant Branch Basin in Dane County, Wisconsin is expected to undergo development. There are concerns that development will adversely affect water resources with increased flood peaks, increased runoff volumes, and increased pollutant loads. To provide a scientific basis for evaluating the hydrologic system response to development the Precipitation Runoff Modeling System (PRMS) was used to model the upper Pheasant Branch Creek watershed with an emphasis on the North Fork Basin. The upper Pheasant Branch Creek (18.3 mi2; 11,700 acres) Basin was represented with 21 Hydrologic Response Units (daily time step) and 50 flow planes (5-minute time steps). Precipitation data from the basin outlet streamflow-gaging station located at Highway 12 and temperature data from a nearby airport were used to drive the model. Continuous discharge records at three gaging stations were used for model calibration. To qualitatively assess model representation of small subbasins, periodic reconnaissance, often including a depth measurement, was made after precipitation to determine the occurrence of flow in ditches and channels from small subbasins. As a further effort to verify the model on a small subbasin scale, continuous-stage sensors (15-minute intervals) measured depth at the outlets of three small subbasins (500 to 1,200 acres). Average annual precipitation for the simulation period from 1993 to 1998 was 35.2 inches. The model simulations showed that, on average, 23.9 inches were intercepted by vegetation, or lost to evapotranspiration, 6.0 inches were infiltrated and moved to the regional ground-water system, and 4.8 inches contributed to the upper Pheasant Branch streamflow. The largest runoff event during the calibration interval was in July 1993 (746 ft3/sec; with a recurrence interval of approximately 25 years). Resulting recharge rates from the calibrated model were subsequently used as input into a ground-water-flow model. Average annual recharge varied spatially from 2.3 inches per year in the highly impervious commercial/industrial area to 9.7 inches per year in the undeveloped North Fork Basin with an average overall recharge rate of 8.1 inches per year. Two development scenarios were examined to assess changes in water-budget fluxes. In scenario A, when development was predominantly low-density residential with 5 to 10 percent commercial development along principal roadways, mean annual streamflow increased by 53 percent, overland flow increased by 84 percent, base flow decreased by 15 percent and annual recharge to the regional ground-water system was reduced by 10 percent. In development scenario B, the entire North Fork and intervening area basins contained 50 percent commercial and 50 percent medium density residential land use. Annual storm runoff increased by over 450 percent. The ground-water model for the Pheasant Branch that used the scenario B recharge rates simulated a lowered water table with zero base flow and that flow from Frederick Springs would be reduced 26 percent from present-day (1993?98) conditions.An additional example application of the model evaluated locations of flood detention ponds and potential recharge areas that may mitigate the changes in flood peaks and ground-water recharge resulting from urbanization. From February 1998 through July 1998, water-quality samples were collected by use of stage-activated automated samplers. Median suspended- sediment concentrations were similar between the North and South Fork Basins (194 and 242 mg/L, respectively); however, for other constituents, North Fork values were considerably higher: median phosphorus concentrations by 4 times (1.5 and 0.35 mg/L), median ammonia concentrations by 13 times (1.9 and 0.14 mg/L), and the phosphorus-to-sediment ratio by more than 6 times (21 and 3.1 mg/g).
Liu, Bo; He, Junxia; Zeng, Fanjiang; Lei, Jiaqiang; Arndt, Stefan K
2016-07-01
The terminal branch orders of plant root systems have been proposed as short-lived 'ephemeral' modules specialized for resource absorption. The occurrence of ephemeral root modules has so far only been reported for a temperate tree species and it is unclear if the concept also applies to other woody (shrub, tree) and herb species. Fine roots of 12 perennial dicotyledonous herb, shrub and tree species were monitored for two growing seasons using a branch-order classification, sequential sampling and rhizotrons in the Taklamakan desert. Two root modules existed in all three plant functional groups. Among the first five branch orders, the first two (perennial herbs, shrubs) or three (trees) root orders were ephemeral and had a primary anatomical structure, high nitrogen (N) concentrations, high respiration rates and very short life spans of 1-4 months, whereas the last two branch orders in all functional groups were perennial, with thicker diameters, no or collapsed cortex, distinct secondary growth, low N concentrations, low respiration rates, but much longer life spans. Ephemeral, short-lived root modules and long-lived, persistent root modules seem to be a general feature across many plant functional groups and could represent a basic root system design. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.
Furniss, Malcolm M; Kegley, Sandra J
2017-06-01
The forests of the northern Rocky Mountains are hosts of nine species of Nearctic conifer-infesting bark beetles of the genus Scolytus Geoffroy. One of these, Scolytus piceae Swaine (Coleoptera: Curculionidae), infests spruces across the continent including Picea engelmannii Parry (Pinaceae) in Idaho. Mature larvae overwintered before transforming to adults, which infested new hosts in early June. Scolytus piceae most commonly infested shaded out lower branches of mature live spruce. In sporadic wind-felled spruce, the beetle infested the terminal portion of branches throughout the crown, whereas another Scolytinae, Polygraphus rufipennis (Kirby), infested the thicker bark basal portion of the same branches. This niche separation resulted from difference in time of their dispersal flight and ability of S. piceae to colonize thin bark by engraving the underlying sapwood. Population recruitment of S. piceae was low in shaded out lower branches, in balance with this limited host resource. Features of the head of S. piceae larvae differed from that reported in literature, including the mandible dentition, antennal field, and pattern of setae on the postlabium. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Maruta, Naomichi; Marumoto, Moegi
2017-01-01
Lung branching morphogenesis has been studied for decades, but the underlying developmental mechanisms are still not fully understood. Cellular movements dynamically change during the branching process, but it is difficult to observe long-term cellular dynamics by in vivo or tissue culture experiments. Therefore, developing an in vitro experimental model of bronchial tree would provide an essential tool for developmental biology, pathology, and systems biology. In this study, we succeeded in reconstructing a bronchial tree in vitro by using primary human bronchial epithelial cells. A high concentration gradient of bronchial epithelial cells was required for branching initiation, whereas homogeneously distributed endothelial cells induced the formation of successive branches. Subsequently, the branches grew in size to the order of millimeter. The developed model contains only two types of cells and it facilitates the analysis of lung branching morphogenesis. By taking advantage of our experimental model, we carried out long-term time-lapse observations, which revealed self-assembly, collective migration with leader cells, rotational motion, and spiral motion of epithelial cells in each developmental event. Mathematical simulation was also carried out to analyze the self-assembly process and it revealed simple rules that govern cellular dynamics. Our experimental model has provided many new insights into lung development and it has the potential to accelerate the study of developmental mechanisms, pattern formation, left–right asymmetry, and disease pathogenesis of the human lung. PMID:28471293
75 FR 37842 - Notice of Issuance of Regulatory Guide
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-30
... INFORMATION CONTACT: R. A. Jervey, Regulatory Guide Development Branch, Division of Engineering, Office of...) 251-7404 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I. Introduction The U.S. Nuclear..., Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc...
NASA Technical Reports Server (NTRS)
Rochon, Gilbert L.
1989-01-01
Parameters were described for spatial database to facilitate drought monitoring and famine early warning in the African Sahel. The proposed system, referred to as the African Drought and Famine Information System (ADFIS) is ultimately recommended for implementation with the NASA/FEMA Spatial Analysis and Modeling System (SAMS), a GIS/Dymanic Modeling software package, currently under development. SAMS is derived from FEMA'S Integration Emergency Management Information System (IEMIS) and the Pacific Northwest Laborotory's/Engineering Topographic Laboratory's Airland Battlefield Environment (ALBE) GIS. SAMS is primarily intended for disaster planning and resource management applications with the developing countries. Sources of data for the system would include the Developing Economics Branch of the U.S. Dept. of Agriculture, the World Bank, Tulane University School of Public Health and Tropical Medicine's Famine Early Warning Systems (FEWS) Project, the USAID's Foreign Disaster Assistance Section, the World Resources Institute, the World Meterological Institute, the USGS, the UNFAO, UNICEF, and the United Nations Disaster Relief Organization (UNDRO). Satellite imagery would include decadal AVHRR imagery and Normalized Difference Vegetation Index (NDVI) values from 1981 to the present for the African continent and selected Landsat scenes for the Sudan pilot study. The system is initially conceived for the MicroVAX 2/GPX, running VMS. To facilitate comparative analysis, a global time-series database (1950 to 1987) is included for a basic set of 125 socio-economic variables per country per year. A more detailed database for the Sahelian countries includes soil type, water resources, agricultural production, agricultural import and export, food aid, and consumption. A pilot dataset for the Sudan with over 2,500 variables from the World Bank's ANDREX system, also includes epidemiological data on incidence of kwashiorkor, marasmus, other nutritional deficiencies, and synergistically-related infectious diseases.
Overview of Glenn Mechanical Components Branch Research
NASA Astrophysics Data System (ADS)
Zakrajsek, James
2002-09-01
Mr. James Zakrajsek, chief of the Mechanical Components Branch, gave an overview of research conducted by the branch. Branch members perform basic research on mechanical components and systems, including gears and bearings, turbine seals, structural and thermal barrier seals, and space mechanisms. The research is focused on propulsion systems for present and advanced aerospace vehicles. For rotorcraft and conventional aircraft, we conduct research to develop technology needed to enable the design of low noise, ultra safe geared drive systems. We develop and validate analytical models for gear crack propagation, gear dynamics and noise, gear diagnostics, bearing dynamics, and thermal analyses of gear systems using experimental data from various component test rigs. In seal research we develop and test advanced turbine seal concepts to increase efficiency and durability of turbine engines. We perform experimental and analytical research to develop advanced thermal barrier seals and structural seals for current and next generation space vehicles. Our space mechanisms research involves fundamental investigation of lubricants, materials, components and mechanisms for deep space and planetary environments.
1986-02-12
for combatting diseases and pests , a precise technology when supplying it with technical resources, effective forms of labor organization and first... combat waste and to decrease the range of grades. Our branch has many collectives which constantly manufacture good products such as the Kolomna...foxtail, wild buckwheats [razvesistaya and vyunkovaya grechishka], goosefoot, stickseed, hemp nettle , field morning glory, knapweed, thistles), which
Forest Health Monitoring in New York, 1996-1999
Northeastern Research Station
2002-01-01
New York has mature forests dominated by hardwood species, but with a significant and varied softwood resource. Most of the trees are healthy, with full crowns (low transparency, high density), little dieback and little damage. American beech tends to be in poorer condition, with thin crowns, higher dieback, and more damage, especially broken and dead branches.
10 CFR 2.802 - Petition for rulemaking.
Code of Federal Regulations, 2014 CFR
2014-01-01
....gov/site-help/e-submittals.html; by e-mail to MSHD.Resource@nrc.gov; or by writing the Office of..., Directives, and Editing Branch on (301) 415-7163, or toll free on (800) 368-5642, or send e-mail to NRCREP... sent either by mail addressed to the U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001; by...
10 CFR 2.802 - Petition for rulemaking.
Code of Federal Regulations, 2013 CFR
2013-01-01
....gov/site-help/e-submittals.html; by e-mail to MSHD.Resource@nrc.gov; or by writing the Office of..., Directives, and Editing Branch on (301) 415-7163, or toll free on (800) 368-5642, or send e-mail to NRCREP... sent either by mail addressed to the U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001; by...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-17
..., OMB Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC... for Change of Program or Place of Training): Activity Under OMB Review AGENCY: Veterans Benefits... Program or Place of Training, VA Form 22-1995. OMB Control Number: 2900-0074. Type of Review: Extension of...
ERIC Educational Resources Information Center
Wayne County Dept. of Substance Abuse Services, Detroit, MI.
Female drug addicts show greater personal distress and have fewer personal resources a9d social supports than other women. To gain new knowledge about female addicts, the Services Research Branch of the National Institute on Drug Abuse funded several research projects to analyze personality, attitudes and value measures of addicted women, support…
Mitigation of Adverse Effects of Long Branch Lake Project upon the Archaeological Resources. Part 1
1986-01-01
ly quartz but with some plagio - clase. Particles are highly rounded. Particles are generally small (.1 to .7 millimeters) but with a few (up to 5...Includes highly rounded, sand- sized particles as well as angular particles, of quartz and plagio - clase. Origin of materials ap- pears to be from sand
Patrick J. Mulholland; Jennifer L. Tank; Diane M. Sanzone; Wilfrid M. Wollheim; Bruce J. Peterson; Jackson R. Webster; Judy L. Meyer
2000-01-01
Trophic relationships were examined using natural-abundance 13C and 15N analyses and a 15N-tracer addition experiment in Walker Branch, a 1st-order forested stream in eastern Tennessee. In the 15N-tracer addition experiment, we added 15NH4...
Thin Client Architecture for Networking CD-ROMs in a Medium-Sized Public Library System.
ERIC Educational Resources Information Center
Turner, Anna
1997-01-01
Describes how the Tulsa City-County Library System built a 22-branch CD-ROM-based network with the emerging thin-client/server technology, and succeeded in providing patrons with the most current research tools and information resources available. Discusses costs; networking options; the Citrix WinFrame system used; equipment and connectivity.…
ERIC Educational Resources Information Center
Committee on the Undergraduate Program in Mathematics, Berkeley, CA.
This report considers the mathematics required by life science students (those with majors in agriculture and renewable resources, all branches of biology, and medicine) who have successfully completed the usual pre-calculus courses. A core is proposed, to include one year of calculus, some linear algebra, and some probability and statistics.…
Condition Assessment of a Historic Trout Rearing Station in Upper Michigan
Frederico J. N. Franca; Tamara S.F. Amorin Franca; Lon A. Yeary; Christopher Hohnholt; John W. Forsman; Robert J. Ross
2015-01-01
Michigan Technological University's (Michigan Tech) School of Forest Resources and Environmental Science maintains a log cabin on the north branch of the Otter River in southern Houghton County (Portage Township), Michigan. The cabin was built in 1934-1935 and measures 150 m2. The cabin's location is less than 10 m from the river, and...
Impact of the Federal School-Based Student Mentoring Program. NCEE Evaluation Brief. NCEE 2009-4074
ERIC Educational Resources Information Center
National Center for Education Evaluation and Regional Assistance, 2009
2009-01-01
The Office of Management and Budget requested that the Institute of Education Sciences (IES) oversee an independent impact evaluation of the federal Student Mentoring Program, and in 2005 IES contracted with Abt Associates and its team of subcontractors (Branch Associates, Moore and Associates, and the Center for Resource Management) to conduct…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-21
... Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC 20503... Management and Budget (OMB) for review and comment. The PRA submission describes the nature of the... of a currently approved collection. Abstract: On-the-job trainers use VA Form 28-1905c to maintain...
An Introduction to ESERO-UK, the UK Space Education Office
ERIC Educational Resources Information Center
Clements, Allan; Mather, Edward
2012-01-01
This article introduces the UK branch of the European Space Education Resource Office (ESERO-UK), also known as the UK Space Education Office. It is a teaching project designed to use space to enthuse primary and secondary students to study science, technology, engineering and mathematics (STEM) subjects. The office is funded by the European Space…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-14
... DEPARTMENT OF THE INTERIOR Bureau of Land Management [61510-8451-0000; MTM 80092] Notice of Proposed Withdrawal Extension and Notification of a Public Meeting; Montana; Correction AGENCY: Bureau of... Staszak, Chief, Branch of Land Resources. [FR Doc. 2011-17716 Filed 7-13-11; 8:45 am] BILLING CODE 4310-55...
75 FR 55604 - Notice of Proposed Withdrawal Extension and Opportunity for Public Meeting; Montana
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-13
... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLMTM01000-L14300000.ET0000; MTM 79264] Notice of Proposed Withdrawal Extension and Opportunity for Public Meeting; Montana AGENCY: Bureau of... Miller, Acting Chief, Branch of Land Resources. [FR Doc. 2010-22740 Filed 9-10-10; 8:45 am] BILLING CODE...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-10
... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLMT924000-L14300000.FR0000; MTM 99415] Notice of Correction to Notice of Realty Action; Application for Recordable Disclaimer of Interest... ``disclaimer''. Cindy Staszak, Chief, Branch of Land Resources. [FR Doc. 2010-2851 Filed 2-9-10; 8:45 am...
Hawaii Island Groundwater Flow Model
Nicole Lautze
2015-01-01
Groundwater flow model for Hawaii Island. Data is from the following sources: Whittier, R.B., K. Rotzoll, S. Dhal, A.I. El-Kadi, C. Ray, G. Chen, and D. Chang. 2004. Hawaii Source Water Assessment Program Report – Volume II – Island of Hawaii Source Water Assessment Program Report. Prepared for the Hawaii Department of Health, Safe Drinking Water Branch. University of Hawaii, Water Resources Research Center. Updated 2008; and Whittier, R. and A.I. El-Kadi. 2014. Human and Environmental Risk Ranking of Onsite Sewage Disposal Systems For the Hawaiian Islands of Kauai, Molokai, Maui, and Hawaii – Final. Prepared by the University of Hawaii, Dept. of Geology and Geophysics for the State of Hawaii Dept. of Health, Safe Drinking Water Branch. September 2014.
Nicole Lautze
2015-01-01
Groundwater flow model for Kauai. Data is from the following sources: Whittier, R. and A.I. El-Kadi. 2014. Human and Environmental Risk Ranking of Onsite Sewage Disposal Systems For the Hawaiian Islands of Kauai, Molokai, Maui, and Hawaii – Final. Prepared by the University of Hawaii, Dept. of Geology and Geophysics for the State of Hawaii Dept. of Health, Safe Drinking Water Branch. September 2014.; and Whittier, R.B., K. Rotzoll, S. Dhal, A.I. El-Kadi, C. Ray, G. Chen, and D. Chang. 2004. Hawaii Source Water Assessment Program Report – Volume IV – Island of Kauai Source Water Assessment Program Report. Prepared for the Hawaii Department of Health, Safe Drinking Water Branch. University of Hawaii, Water Resources Research Center. Updated 2015.
East Maui Groundwater Flow Model
Nicole Lautze
2015-01-01
Groundwater flow model for East Maui. Data is from the following sources: Whittier, R. and A.I. El-Kadi. 2014. Human and Environmental Risk Ranking of Onsite Sewage Disposal Systems For the Hawaiian Islands of Kauai, Molokai, Maui, and Hawaii – Final. Prepared by the University of Hawaii, Dept. of Geology and Geophysics for the State of Hawaii Dept. of Health, Safe Drinking Water Branch. September 2014; and Whittier, R.B., K. Rotzoll, S. Dhal, A.I. El-Kadi, C. Ray, G. Chen, and D. Chang. 2004. Hawaii Source Water Assessment Program Report – Volume V – Island of Maui Source Water Assessment Program Report. Prepared for the Hawaii Department of Health, Safe Drinking Water Branch. University of Hawaii, Water Resources Research Center. Updated 2008.
West Maui Groundwater Flow Model
Nicole Lautze
2015-01-01
Groundwater flow model for West Maui. Data is from the following sources: Whittier, R. and A.I. El-Kadi. 2014. Human and Environmental Risk Ranking of Onsite Sewage Disposal Systems For the Hawaiian Islands of Kauai, Molokai, Maui, and Hawaii – Final. Prepared by the University of Hawaii, Dept. of Geology and Geophysics for the State of Hawaii Dept. of Health, Safe Drinking Water Branch. September 2014; and Whittier, R.B., K. Rotzoll, S. Dhal, A.I. El-Kadi, C. Ray, G. Chen, and D. Chang. 2004. Hawaii Source Water Assessment Program Report – Volume V – Island of Maui Source Water Assessment Program Report. Prepared for the Hawaii Department of Health, Safe Drinking Water Branch. University of Hawaii, Water Resources Research Center. Updated 2008.
2012-01-01
Background The OpenTox Framework, developed by the partners in the OpenTox project (http://www.opentox.org), aims at providing a unified access to toxicity data, predictive models and validation procedures. Interoperability of resources is achieved using a common information model, based on the OpenTox ontologies, describing predictive algorithms, models and toxicity data. As toxicological data may come from different, heterogeneous sources, a deployed ontology, unifying the terminology and the resources, is critical for the rational and reliable organization of the data, and its automatic processing. Results The following related ontologies have been developed for OpenTox: a) Toxicological ontology – listing the toxicological endpoints; b) Organs system and Effects ontology – addressing organs, targets/examinations and effects observed in in vivo studies; c) ToxML ontology – representing semi-automatic conversion of the ToxML schema; d) OpenTox ontology– representation of OpenTox framework components: chemical compounds, datasets, types of algorithms, models and validation web services; e) ToxLink–ToxCast assays ontology and f) OpenToxipedia community knowledge resource on toxicology terminology. OpenTox components are made available through standardized REST web services, where every compound, data set, and predictive method has a unique resolvable address (URI), used to retrieve its Resource Description Framework (RDF) representation, or to initiate the associated calculations and generate new RDF-based resources. The services support the integration of toxicity and chemical data from various sources, the generation and validation of computer models for toxic effects, seamless integration of new algorithms and scientifically sound validation routines and provide a flexible framework, which allows building arbitrary number of applications, tailored to solving different problems by end users (e.g. toxicologists). Availability The OpenTox toxicological ontology projects may be accessed via the OpenTox ontology development page http://www.opentox.org/dev/ontology; the OpenTox ontology is available as OWL at http://opentox.org/api/1 1/opentox.owl, the ToxML - OWL conversion utility is an open source resource available at http://ambit.svn.sourceforge.net/viewvc/ambit/branches/toxml-utils/ PMID:22541598
Tcheremenskaia, Olga; Benigni, Romualdo; Nikolova, Ivelina; Jeliazkova, Nina; Escher, Sylvia E; Batke, Monika; Baier, Thomas; Poroikov, Vladimir; Lagunin, Alexey; Rautenberg, Micha; Hardy, Barry
2012-04-24
The OpenTox Framework, developed by the partners in the OpenTox project (http://www.opentox.org), aims at providing a unified access to toxicity data, predictive models and validation procedures. Interoperability of resources is achieved using a common information model, based on the OpenTox ontologies, describing predictive algorithms, models and toxicity data. As toxicological data may come from different, heterogeneous sources, a deployed ontology, unifying the terminology and the resources, is critical for the rational and reliable organization of the data, and its automatic processing. The following related ontologies have been developed for OpenTox: a) Toxicological ontology - listing the toxicological endpoints; b) Organs system and Effects ontology - addressing organs, targets/examinations and effects observed in in vivo studies; c) ToxML ontology - representing semi-automatic conversion of the ToxML schema; d) OpenTox ontology- representation of OpenTox framework components: chemical compounds, datasets, types of algorithms, models and validation web services; e) ToxLink-ToxCast assays ontology and f) OpenToxipedia community knowledge resource on toxicology terminology.OpenTox components are made available through standardized REST web services, where every compound, data set, and predictive method has a unique resolvable address (URI), used to retrieve its Resource Description Framework (RDF) representation, or to initiate the associated calculations and generate new RDF-based resources.The services support the integration of toxicity and chemical data from various sources, the generation and validation of computer models for toxic effects, seamless integration of new algorithms and scientifically sound validation routines and provide a flexible framework, which allows building arbitrary number of applications, tailored to solving different problems by end users (e.g. toxicologists). The OpenTox toxicological ontology projects may be accessed via the OpenTox ontology development page http://www.opentox.org/dev/ontology; the OpenTox ontology is available as OWL at http://opentox.org/api/1 1/opentox.owl, the ToxML - OWL conversion utility is an open source resource available at http://ambit.svn.sourceforge.net/viewvc/ambit/branches/toxml-utils/
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-12
... the State of Hawai`i Department of Business, Economic Development and Tourism (DBEDT), which is a co... Hawai'i, Department of Business, Economic Development and Tourism, Renewable Energy Branch, State Energy..., Economic Development and Tourism, Renewable Energy Branch, State Energy Office, P.O. Box 2359, Honolulu, HI...
Pricing and reimbursement frameworks in Central Eastern Europe: a decision tool to support choices.
Kolasa, Katarzyna; Kalo, Zoltan; Hornby, Edward
2015-02-01
Given limited financial resources in the Central Eastern European (CEE) region, challenges in obtaining access to innovative medical technologies are formidable. The objective of this research was to develop a decision tree that supports decision makers and drug manufacturers from CEE region in their search for optimal innovative pricing and reimbursement scheme (IPRSs). A systematic literature review was performed to search for published IPRSs, and then ten experts from the CEE region were interviewed to ascertain their opinions on these schemes. In total, 33 articles representing 46 unique IPRSs were analyzed. Based on our literature review and subsequent expert input, key decision nodes and branches of the decision tree were developed. The results indicate that outcome-based schemes are better suited to deal with uncertainties surrounding cost effectiveness, while non-outcome-based schemes are more appropriate for pricing and budget impact challenges.
Superradiant Quantum Heat Engine.
Hardal, Ali Ü C; Müstecaplıoğlu, Özgür E
2015-08-11
Quantum physics revolutionized classical disciplines of mechanics, statistical physics, and electrodynamics. One branch of scientific knowledge however seems untouched: thermodynamics. Major motivation behind thermodynamics is to develop efficient heat engines. Technology has a trend to miniaturize engines, reaching to quantum regimes. Development of quantum heat engines (QHEs) requires emerging field of quantum thermodynamics. Studies of QHEs debate whether quantum coherence can be used as a resource. We explore an alternative where it can function as an effective catalyst. We propose a QHE which consists of a photon gas inside an optical cavity as the working fluid and quantum coherent atomic clusters as the fuel. Utilizing the superradiance, where a cluster can radiate quadratically faster than a single atom, we show that the work output becomes proportional to the square of the number of the atoms. In addition to practical value of cranking up QHE, our result is a fundamental difference of a quantum fuel from its classical counterpart.
Academic Branch Libraries: Assessment and Collection Development
ERIC Educational Resources Information Center
Poole, Julie
2009-01-01
An ongoing project at Mercer University's Regional Academic Center Libraries illustrates how utilizing established assessment guidelines, stakeholder input, and a clear understanding of audience and curriculum needs may all be used to optimize a collection. Academic branch libraries often have clear collection development limitations in terms of…
Mental Retardation and Developmental Disabilities (MRDD) Branch. NICHD Report to the NACHHD Council
ERIC Educational Resources Information Center
National Institute of Child Health and Human Development (NICHD), 2005
2005-01-01
This document is the quadrennial report of the Mental Retardation and Developmental Disabilities (MRDD) Branch to the National Advisory Child Health and Human Development (NACHHD) Council. The MRDD Branch is a vital, evolving entity within the Center for Developmental Biology and Perinatal Medicine (CDBPM) at the National Institute of Child …
Mental Retardation and Developmental Disabilities Branch (NICHD) Report to the NACHHD Council.
ERIC Educational Resources Information Center
National Inst. of Child Health and Human Development (NIH), Bethesda, MD. Mental Retardation and Developmental Disabilities Branch.
This report highlights some of the projects supported by the Mental Retardation and Developmental Disabilities (MRDD) Branch of the Center for Research for Mothers and Children at the National Institute of Child Health and Human Development since its last report in January 1997. The MRDD Branch provides support for research, research training,…
Evolutionary Multiobjective Query Workload Optimization of Cloud Data Warehouses
Dokeroglu, Tansel; Sert, Seyyit Alper; Cinar, Muhammet Serkan
2014-01-01
With the advent of Cloud databases, query optimizers need to find paretooptimal solutions in terms of response time and monetary cost. Our novel approach minimizes both objectives by deploying alternative virtual resources and query plans making use of the virtual resource elasticity of the Cloud. We propose an exact multiobjective branch-and-bound and a robust multiobjective genetic algorithm for the optimization of distributed data warehouse query workloads on the Cloud. In order to investigate the effectiveness of our approach, we incorporate the devised algorithms into a prototype system. Finally, through several experiments that we have conducted with different workloads and virtual resource configurations, we conclude remarkable findings of alternative deployments as well as the advantages and disadvantages of the multiobjective algorithms we propose. PMID:24892048
Virtual Control Policy for Binary Ordered Resources Petri Net Class
Rovetto, Carlos A.; Concepción, Tomás J.; Cano, Elia Esther
2016-01-01
Prevention and avoidance of deadlocks in sensor networks that use the wormhole routing algorithm is an active research domain. There are diverse control policies that will address this problem being our approach a new method. In this paper we present a virtual control policy for the new specialized Petri net subclass called Binary Ordered Resources Petri Net (BORPN). Essentially, it is an ordinary class constructed from various state machines that share unitary resources in a complex form, which allows branching and joining of processes. The reduced structure of this new class gives advantages that allow analysis of the entire system’s behavior, which is a prohibitive task for large systems because of the complexity and routing algorithms. PMID:27548170
Xu, Weinan; Ledin, Petr A; Shevchenko, Valery V; Tsukruk, Vladimir V
2015-06-17
Branched polyelectrolytes with cylindrical brush, dendritic, hyperbranched, grafted, and star architectures bearing ionizable functional groups possess complex and unique assembly behavior in solution at surfaces and interfaces as compared to their linear counterparts. This review summarizes the recent developments in the introduction of various architectures and understanding of the assembly behavior of branched polyelectrolytes with a focus on functional polyelectrolytes and poly(ionic liquid)s with responsive properties. The branched polyelectrolytes and poly(ionic liquid)s interact electrostatically with small molecules, linear polyelectrolytes, or other branched polyelectrolytes to form assemblies of hybrid nanoparticles, multilayer thin films, responsive microcapsules, and ion-conductive membranes. The branched structures lead to unconventional assemblies and complex hierarchical structures with responsive properties as summarized in this review. Finally, we discuss prospectives for emerging applications of branched polyelectrolytes and poly(ionic liquid)s for energy harvesting and storage, controlled delivery, chemical microreactors, adaptive surfaces, and ion-exchange membranes.
Modern prospects of development of branch of solar power
NASA Astrophysics Data System (ADS)
Luchkina, Veronika
2017-10-01
Advantages of solar energy for modern companies are evident already. Article describes mechanism of the solar electricity generation. Process of production of solar modules with appliance of the modern technologies of sun energy production. The branch of solar energy “green energy” become advanced in Russia and has a stable demand. Classification of investments on the different stages of construction projects of solar power plants and calculation of their economic efficiency. Studying of introduction of these technologies allows to estimate the modern prospects of development of branch of solar power.
Strategic Planning for Research in Pediatric Critical Care.
Tamburro, Robert F; Jenkins, Tammara L; Kochanek, Patrick M
2016-11-01
To summarize the scientific priorities and potential future research directions for pediatric critical care research discussed by a panel of experts at the inaugural Strategic Planning Conference of the Pediatric Trauma and Critical Illness Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Expert opinion expressed during the Strategic Planning Conference. Not applicable. Chaired by an experienced expert from the field, issues relevant to the conduct of pediatric critical care research were discussed and debated by the invited participants. Common themes and suggested priorities were identified and coalesced. Of the many pathophysiologic conditions discussed, the multiple organ dysfunction syndrome emerged as a topic in need of more study that is most relevant to the field. Additionally, the experts offered that the interrelationship and impact of critical illness on child development and family functioning are important research priorities. Consequently, long-term outcomes research was encouraged. The expert group also suggested that multidisciplinary conferences are needed to help identify key knowledge gaps to advance and direct research in the field. The Pediatric Critical Care and Trauma Scientist Development National K12 Program and the Collaborative Pediatric Critical Care Research Network were recognized as successful and important programs supported by the branch. The development of core data resources including biorepositories with robust phenotypic data using common data elements was also suggested to foster data sharing among investigators and to enhance disease diagnosis and discovery. Multicenter clinical trials and innovative study designs to address understudied and poorly understood conditions were considered important for field advancement. Finally, the growth of the pediatric critical care research workforce was offered as a priority that could be spawned in many ways including by expanded transdisciplinary and multiprofessional collaboration and diversity representation.
Strategic Planning for Research in Pediatric Critical Care
Tamburro, Robert F.; Jenkins, Tammara L.; Kochanek, Patrick M.
2016-01-01
Objective To summarize the scientific priorities and potential future research directions for pediatric critical care research discussed by a panel of experts at the inaugural Strategic Planning Conference of the Pediatric Trauma and Critical Illness Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Data Sources Expert opinion expressed during the Strategic Planning Conference. Study Selection Not applicable Data Extraction Chaired by an experienced expert from the field, issues relevant to the conduct of pediatric critical care research were discussed and debated by the invited participants. Data Synthesis Common themes and suggested priorities were identified and coalesced. Conclusions Of the many pathophysiological conditions discussed, the multiple organ dysfunction syndrome emerged as a topic in need of more study that is most relevant to the field. Additionally, the experts offered that the inter-relationship and impact of critical illness on child development and family functioning are important research priorities. Consequently, long-term outcomes research was encouraged. The expert group also suggested that multidisciplinary conferences are needed to help identify key knowledge gaps to advance and direct research in the field. The Pediatric Critical Care and Trauma Scientist Development National K12 Program and the Collaborative Pediatric Critical Care Research Network were recognized as successful and important programs supported by the branch. The development of core data resources including biorepositories with robust phenotypic data using common data elements was also suggested to foster data sharing among investigators and to enhance disease diagnosis and discovery. Multicenter clinical trials and innovative study designs to address understudied and poorly understood conditions were considered important for field advancement. Finally, the growth of the pediatric critical care research workforce was offered as a priority that could be spawned in many ways including by expanded transdisciplinary and multiprofessional collaboration and diversity representation. PMID:27679964
Leading Process Branch Instability in Lis1+/− Nonradially Migrating Interneurons
Gopal, Pallavi P.; Simonet, Jacqueline C.; Shapiro, William
2010-01-01
Mammalian forebrain development requires extensive migration, yet the mechanisms through which migrating neurons sense and respond to guidance cues are not well understood. Similar to the axon growth cone, the leading process and branches of neurons may guide migration, but the cytoskeletal events that regulate branching are unknown. We have previously shown that loss of microtubule-associated protein Lis1 reduces branching during migration compared with wild-type neurons. Using time-lapse imaging of Lis1+/− and Lis1+/+ cells migrating from medial ganglionic eminence explant cultures, we show that the branching defect is not due to a failure to initiate branches but a defect in the stabilization of new branches. The leading processes of Lis1+/− neurons have reduced expression of stabilized, acetylated microtubules compared with Lis1+/+ neurons. To determine whether Lis1 modulates branch stability through its role as the noncatalytic β regulatory subunit of platelet-activating factor (PAF) acetylhydrolase 1b, exogenous PAF was applied to wild-type cells. Excess PAF added to wild-type neurons phenocopies the branch instability observed in Lis1+/− neurons, and a PAF antagonist rescues leading process branching in Lis1+/− neurons. These data highlight a role for Lis1, acting through the PAF pathway, in leading process branching and microtubule stabilization. PMID:19861636
Nock, Charles A.; Lecigne, Bastien; Taugourdeau, Olivier; Greene, David F.; Dauzat, Jean; Delagrange, Sylvain; Messier, Christian
2016-01-01
Background and Aims Despite a longstanding interest in variation in tree species vulnerability to ice storm damage, quantitative analyses of the influence of crown structure on within-crown variation in ice accretion are rare. In particular, the effect of prior interception by higher branches on lower branch accumulation remains unstudied. The aim of this study was to test the hypothesis that intra-crown ice accretion can be predicted by a measure of the degree of sheltering by neighbouring branches. Methods Freezing rain was artificially applied to Acer platanoides L., and in situ branch-ice thickness was measured directly and from LiDAR point clouds. Two models of freezing rain interception were developed: ‘IceCube’, which uses point clouds to relate ice accretion to a voxel-based index (sheltering factor; SF) of the sheltering effect of branch elements above a measurement point; and ‘IceTree’, a simulation model for in silico evaluation of the interception pattern of freezing rain in virtual tree crowns. Key Results Intra-crown radial ice accretion varied strongly, declining from the tips to the bases of branches and from the top to the base of the crown. SF for branches varied strongly within the crown, and differences among branches were consistent for a range of model parameters. Intra-crown variation in ice accretion on branches was related to SF (R2 = 0·46), with in silico results from IceTree supporting empirical relationships from IceCube. Conclusions Empirical results and simulations confirmed a key role for crown architecture in determining intra-crown patterns of ice accretion. As suspected, the concentration of freezing rain droplets is attenuated by passage through the upper crown, and thus higher branches accumulate more ice than lower branches. This is the first step in developing a model that can provide a quantitative basis for investigating intra-crown and inter-specific variation in freezing rain damage. PMID:27107412
Nambeesan, Savithri U; Mandel, Jennifer R; Bowers, John E; Marek, Laura F; Ebert, Daniel; Corbi, Jonathan; Rieseberg, Loren H; Knapp, Steven J; Burke, John M
2015-03-11
Shoot branching is an important determinant of plant architecture and influences various aspects of growth and development. Selection on branching has also played an important role in the domestication of crop plants, including sunflower (Helianthus annuus L.). Here, we describe an investigation of the genetic basis of variation in branching in sunflower via association mapping in a diverse collection of cultivated sunflower lines. Detailed phenotypic analyses revealed extensive variation in the extent and type of branching within the focal population. After correcting for population structure and kinship, association analyses were performed using a genome-wide collection of SNPs to identify genomic regions that influence a variety of branching-related traits. This work resulted in the identification of multiple previously unidentified genomic regions that contribute to variation in branching. Genomic regions that were associated with apical and mid-apical branching were generally distinct from those associated with basal and mid-basal branching. Homologs of known branching genes from other study systems (i.e., Arabidopsis, rice, pea, and petunia) were also identified from the draft assembly of the sunflower genome and their map positions were compared to those of associations identified herein. Numerous candidate branching genes were found to map in close proximity to significant branching associations. In sunflower, variation in branching is genetically complex and overall branching patterns (i.e., apical vs. basal) were found to be influenced by distinct genomic regions. Moreover, numerous candidate branching genes mapped in close proximity to significant branching associations. Although the sunflower genome exhibits localized islands of elevated linkage disequilibrium (LD), these non-random associations are known to decay rapidly elsewhere. The subset of candidate genes that co-localized with significant associations in regions of low LD represents the most promising target for future functional analyses.
The Direction of Fluid Dynamics for Liquid Propulsion at NASA Marshall Space Flight Center
NASA Technical Reports Server (NTRS)
Griffin, Lisa W.
2012-01-01
Marshall Space Flight Center (MSFC) is the National Aeronautics and Space Administration (NASA)-designated center for the development of space launch systems. MSFC is particularly known for propulsion system development. Many engineering skills and technical disciplines are needed to accomplish this mission. This presentation will focus on the work of the Fluid Dynamics Branch (ER42). ER42 resides in the Propulsion Systems Department at MSFC. The branch is responsible for all aspects of the discipline of fluid dynamics applied to propulsion or propulsion-induced loads and environments. This work begins with design trades and parametric studies, and continues through development, risk assessment, anomaly investigation and resolution, and failure investigations. Applications include the propellant delivery system including the main propulsion system (MPS) and turbomachinery; combustion devices for liquid engines and solid rocket motors; coupled systems; and launch environments. An advantage of the branch is that it is neither analysis nor test centric, but discipline centric. Fluid dynamics assessments are made by analysis, from lumped parameter modeling through unsteady computational fluid dynamics (CFD); testing, which can be cold flow or hot fire; or a combination of analysis and testing. Integration of all discipline methods into one branch enables efficient and accurate support to the projects. To accomplish this work, the branch currently employs approximately fifty engineers divided into four teams -- Propellant Delivery CFD, Combustion Driven Flows CFD, Unsteady and Experimental Flows, and Acoustics and Stability. This discussion will highlight some of the work performed in the branch and the direction in which the branch is headed.
Geographic Information Systems and Web Page Development
NASA Technical Reports Server (NTRS)
Reynolds, Justin
2004-01-01
The Facilities Engineering and Architectural Branch is responsible for the design and maintenance of buildings, laboratories, and civil structures. In order to improve efficiency and quality, the FEAB has dedicated itself to establishing a data infrastructure based on Geographic Information Systems, GIs. The value of GIS was explained in an article dating back to 1980 entitled "Need for a Multipurpose Cadastre which stated, "There is a critical need for a better land-information system in the United States to improve land-conveyance procedures, furnish a basis for equitable taxation, and provide much-needed information for resource management and environmental planning." Scientists and engineers both point to GIS as the solution. What is GIS? According to most text books, Geographic Information Systems is a class of software that stores, manages, and analyzes mapable features on, above, or below the surface of the earth. GIS software is basically database management software to the management of spatial data and information. Simply put, Geographic Information Systems manage, analyze, chart, graph, and map spatial information. At the outset, I was given goals and expectations from my branch and from my mentor with regards to the further implementation of GIs. Those goals are as follows: (1) Continue the development of GIS for the underground structures. (2) Extract and export annotated data from AutoCAD drawing files and construct a database (to serve as a prototype for future work). (3) Examine existing underground record drawings to determine existing and non-existing underground tanks. Once this data was collected and analyzed, I set out on the task of creating a user-friendly database that could be assessed by all members of the branch. It was important that the database be built using programs that most employees already possess, ruling out most AutoCAD-based viewers. Therefore, I set out to create an Access database that translated onto the web using Internet Explorer as the foundation. After some programming, it was possible to view AutoCAD files and other GIS-related applications on Internet Explorer, while providing the user with a variety of editing commands and setting options. I was also given the task of launching a divisional website using Macromedia Flash and other web- development programs.
Hikspoors, Jill P J M; Peeters, Mathijs M J P; Kruepunga, Nutmethee; Mekonen, Hayelom K; Mommen, Greet M C; Köhler, S Eleonore; Lamers, Wouter H
2017-12-07
Couinaud based his well-known subdivision of the liver into (surgical) segments on the branching order of portal veins and the location of hepatic veins. However, both segment boundaries and number remain controversial due to an incomplete understanding of the role of liver lobes and vascular physiology on hepatic venous development. Human embryonic livers (5-10 weeks of development) were visualized with Amira 3D-reconstruction and Cinema 4D-remodeling software. Starting at 5 weeks, the portal and umbilical veins sprouted portal-vein branches that, at 6.5 weeks, had been pruned to 3 main branches in the right hemi-liver, whereas all (>10) persisted in the left hemi-liver. The asymmetric branching pattern of the umbilical vein resembled that of a "distributing" vessel, whereas the more symmetric branching of the portal trunk resembled a "delivering" vessel. At 6 weeks, 3-4 main hepatic-vein outlets drained into the inferior caval vein, of which that draining the caudate lobe formed the intrahepatic portion of the caval vein. More peripherally, 5-6 major tributaries drained both dorsolateral regions and the left and right ventromedial regions, implying a "crypto-lobar" distribution. Lobar boundaries, even in non-lobated human livers, and functional vascular requirements account for the predictable topography and branching pattern of the liver veins, respectively.
Bai, Fang; Reinheimer, Renata; Durantini, Diego; Kellogg, Elizabeth A; Schmidt, Robert J
2012-07-24
In grass inflorescences, a structure called the "pulvinus" is found between the inflorescence main stem and lateral branches. The size of the pulvinus affects the angle of the lateral branches that emerge from the main axis and therefore has a large impact on inflorescence architecture. Through EMS mutagenesis we have identified three complementation groups of recessive mutants in maize having defects in pulvinus formation. All mutants showed extremely acute tassel branch angles accompanied by a significant reduction in the size of the pulvinus compared with normal plants. Two of the complementation groups correspond to mutations in the previously identified genes, RAMOSA2 (RA2) and LIGULELESS1 (LG1). Mutants corresponding to a third group were cloned using mapped-based approaches and found to encode a new member of the plant-specific TCP (TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL NUCLEAR ANTIGEN FACTOR) family of DNA-binding proteins, BRANCH ANGLE DEFECTIVE 1 (BAD1). BAD1 is expressed in the developing pulvinus as well as in other developing tissues, including the tassels and juvenile leaves. Both molecular and genetics studies show that RA2 is upstream of BAD1, whereas LG1 may function in a separate pathway. Our findings demonstrate that BAD1 is a TCP class II gene that functions to promote cell proliferation in a lateral organ, the pulvinus, and influences inflorescence architecture by impacting the angle of lateral branch emergence.
Model-based branching point detection in single-cell data by K-branches clustering
Chlis, Nikolaos K.; Wolf, F. Alexander; Theis, Fabian J.
2017-01-01
Abstract Motivation The identification of heterogeneities in cell populations by utilizing single-cell technologies such as single-cell RNA-Seq, enables inference of cellular development and lineage trees. Several methods have been proposed for such inference from high-dimensional single-cell data. They typically assign each cell to a branch in a differentiation trajectory. However, they commonly assume specific geometries such as tree-like developmental hierarchies and lack statistically sound methods to decide on the number of branching events. Results We present K-Branches, a solution to the above problem by locally fitting half-lines to single-cell data, introducing a clustering algorithm similar to K-Means. These halflines are proxies for branches in the differentiation trajectory of cells. We propose a modified version of the GAP statistic for model selection, in order to decide on the number of lines that best describe the data locally. In this manner, we identify the location and number of subgroups of cells that are associated with branching events and full differentiation, respectively. We evaluate the performance of our method on single-cell RNA-Seq data describing the differentiation of myeloid progenitors during hematopoiesis, single-cell qPCR data of mouse blastocyst development, single-cell qPCR data of human myeloid monocytic leukemia and artificial data. Availability and implementation An R implementation of K-Branches is freely available at https://github.com/theislab/kbranches. Contact fabian.theis@helmholtz-muenchen.de Supplementary information Supplementary data are available at Bioinformatics online. PMID:28582478
Robinson, Nicholas P
2013-01-01
Branched DNA molecules are generated by the essential processes of replication and recombination. Owing to their distinctive extended shapes, these intermediates migrate differently from linear double-stranded DNA under certain electrophoretic conditions. However, these branched species exist in the cell at much low abundance than the bulk linear DNA. Consequently, branched molecules cannot be visualized by conventional electrophoresis and ethidium bromide staining. Two-dimensional native-native agarose electrophoresis has therefore been developed as a method to facilitate the separation and visualization of branched replication and recombination intermediates. A wide variety of studies have employed this technique to examine branched molecules in eukaryotic, archaeal, and bacterial cells, providing valuable insights into how DNA is duplicated and repaired in all three domains of life.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-20
...-9460. 4. Mail: Steven Brown, Atmospheric Section, Air Planning and Development Branch, Air and Waste..., Kansas 66101. 5. Hand Delivery or Courier: Steven Brown, Atmospheric Section, Air Planning and... Atmospheric Section, Air Planning and Development Branch, Air Waste and Management Division, U.S...
Harsant, Jeffrey; Pavlovic, Lazar; Chiu, Greta; Sultmanis, Stefanie; Sage, Tammy L.
2013-01-01
The effect of high temperatures on harvest index (HI) and morphological components that contribute to HI was investigated in two lines (Bd21 and Bd21-3) of Brachypodium distachyon, a C3 grass recognized as a tractable plant, to address critical issues associated with enhancing cereal crop yields in the presence of global climate change. The results demonstrated that temperatures ≥32 °C eliminated HI. Reductions in yield at 32 °C were due primarily to declines in pollen viability, retention of pollen in anthers, and pollen germination, while abortion of microspores by the uninucleate stage that was correlated with abnormal tapetal development resulted in yield failure at 36 °C. Increasing temperatures from 24 to 32 °C resulted in reductions in tiller numbers but had no impact on axillary branch numbers per tiller. Grain developed at 24 and 28 °C primarily in tiller spikes, although spikes on axillary branches also formed grain. Grain quantity decreased in tiller spikes but increased in axillary branch spikes as temperatures rose from 24 to 28 °C. Differential patterns of axillary branching and floret development within spikelets between Bd21 and Bd21-3 resulted in higher grain yield in axillary branches of Bd21-3 at 28 °C. The response of male reproductive development and tiller branching patterns in B. distachyon to increasing temperatures mirrors that in other cereal crops, providing support for the use of this C3 grass in assessing the molecular control of HI in the presence of global warming. PMID:23771979
[Croatian Medical Association--Branch Zagreb].
Kaić, Zvonimir; Sain, Snjezana; Gulić, Mirjana; Mahovlić, Vjekoslav; Krznarić, Zeljko
2014-01-01
The available literature shows us that "Druztvo ljeciteljah u Zagrebus (the Society of Healers in Zagreb) was founded as far back as the year 1845 by a total of thirteen members. This data allows us to follow the role of doctors and health workers in Zagreb through their everyday profession, research, organizational and social work as well as management through a period of over one hundred to seventy years. The Branch Zagreb was active before the official establishment of subsidiaries of CMA which is evident from the minutes of the regular annual assembly of the Croatian Medical Association on 21 March 1948. Until the end of 1956, there was no clear division of labor, functions and competencies between the Branch and the Main Board. Their actions were instead consolidated and the Branch operated within and under the name of Croatian Medical Association. In that year the Branch became independent. The Branch Zagreb is the largest and one of the most active branches of the Croatian Medical Association. At the moment, the Branch brings together 3621 members, regular members--doctors of medicine (2497), doctors of dental medicine (384), retired physicians (710), and associate members (30 specialists with higher education who are not doctors). The Branch is especially accomplished in its activities in the area of professional development of its members and therefore organizes a series of scientific conferences in the framework of continuous education of physicians, allowing its members to acquire necessary points for the extension of their operating license. The choir "Zagrebacki lijecnici pjevaci" (Zagreb Physicians' Choir) of the Croatian Medical Music Society of the CMA and its activities are inseparable from the Branch Zagreb. The Branch is firmly linked to the parent body, the CMA, and thus has a visible impact on the strategy and the activities of the Association as a whole. Most professional societies of the CMA have their headquarters in Zagreb and this is inevitably reflected in their overall function. The Branch Zagreb supports the harmonious development of health care throughout the territory of the Republic of Croatia. Cities of Zagreb and Mainz, are cities--friends and the CMA Branch Zagreb works together and exchanges visits with mem- bers of the Medical Society of Mainz for years. Next year professional and scientific cooperation between the Branch Za- greb of CMA and the Medical Society of Mainz will mark four decades.
Factual data for public-supply wells and selected irrigation wells in Monmouth County, New Jersey
Jablonski, Leo A.
1960-01-01
The investigation of the ground-water resources of Monmouth County is part of a Statewide water-resources program. This study was made by the U.S. Geological Survey in cooperation with the new Jersey Department of Conservation and Economic Development, Division of Water Policy and Supply. It was under the general direction of Philip E. LaMoreaux, Chief of the Ground Water Branch of the U.S. Geological Survey, and under the direct supervision of Allen Sinnott, District Geologist.This report presents data for most of the public-supply wells and for several irrigation wells in Monmouth County. The data for these wells are believed to be representative of large-capacity wells tapping the major aquifers present in the county. The information is released at this time in advance of an interpretive report because of its value to prospective users of ground water in Monmouth County. An earlier report presented data on small-capacity wells tapping both major and minor aquifers in the county. The data in these two reports form, in part, the basis for a comprehensive interpretive report on the ground-water resources of Monmouth County, now in preparation. Also to be included in the latter report are data for certain large-capacity industrial wells.
Cochran, Marlo Baker; Snyder, Russell R; Thomas, Elizabeth; Freeman, Daniel H; Hankins, Gary D V
2012-04-01
This study investigated the utilization of health information technology (HIT) to enhance resource utilization in a geographically dispersed tertiary care system with extensive outpatient and delivery services. It was initiated as a result of a systems change implemented after Hurricane Ike devastated southeast Texas. A retrospective database and electronic medical record review was performed, which included data collection from all patients evaluated 18 months prior (epoch I) and 18 months following (epoch II) the landfall of Hurricane Ike. The months immediately following the storm were omitted from the analysis, allowing time to establish a new baseline. We analyzed a total of 21,201 patients evaluated in triage at the University of Texas Medical Branch. Epoch I consisted of 11,280 patients and epoch II consisted of 9922 patients. Using HIT, we were able to decrease the number of visits to triage while simultaneously managing more complex patients in the outpatient setting with no clinically significant change in maternal or fetal outcome. This study developed an innovated model of care using constrained resources while providing quality and safety to our patients without additional cost to the health care delivery system. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Modelling Root Systems Using Oriented Density Distributions
NASA Astrophysics Data System (ADS)
Dupuy, Lionel X.
2011-09-01
Root architectural models are essential tools to understand how plants access and utilize soil resources during their development. However, root architectural models use complex geometrical descriptions of the root system and this has limitations to model interactions with the soil. This paper presents the development of continuous models based on the concept of oriented density distribution function. The growth of the root system is built as a hierarchical system of partial differential equations (PDEs) that incorporate single root growth parameters such as elongation rate, gravitropism and branching rate which appear explicitly as coefficients of the PDE. Acquisition and transport of nutrients are then modelled by extending Darcy's law to oriented density distribution functions. This framework was applied to build a model of the growth and water uptake of barley root system. This study shows that simplified and computer effective continuous models of the root system development can be constructed. Such models will allow application of root growth models at field scale.
Zeng, Victor; Ewen-Campen, Ben; Horch, Hadley W.; Roth, Siegfried; Mito, Taro; Extavour, Cassandra G.
2013-01-01
Most genomic resources available for insects represent the Holometabola, which are insects that undergo complete metamorphosis like beetles and flies. In contrast, the Hemimetabola (direct developing insects), representing the basal branches of the insect tree, have very few genomic resources. We have therefore created a large and publicly available transcriptome for the hemimetabolous insect Gryllus bimaculatus (cricket), a well-developed laboratory model organism whose potential for functional genetic experiments is currently limited by the absence of genomic resources. cDNA was prepared using mRNA obtained from adult ovaries containing all stages of oogenesis, and from embryo samples on each day of embryogenesis. Using 454 Titanium pyrosequencing, we sequenced over four million raw reads, and assembled them into 21,512 isotigs (predicted transcripts) and 120,805 singletons with an average coverage per base pair of 51.3. We annotated the transcriptome manually for over 400 conserved genes involved in embryonic patterning, gametogenesis, and signaling pathways. BLAST comparison of the transcriptome against the NCBI non-redundant protein database (nr) identified significant similarity to nr sequences for 55.5% of transcriptome sequences, and suggested that the transcriptome may contain 19,874 unique transcripts. For predicted transcripts without significant similarity to known sequences, we assessed their similarity to other orthopteran sequences, and determined that these transcripts contain recognizable protein domains, largely of unknown function. We created a searchable, web-based database to allow public access to all raw, assembled and annotated data. This database is to our knowledge the largest de novo assembled and annotated transcriptome resource available for any hemimetabolous insect. We therefore anticipate that these data will contribute significantly to more effective and higher-throughput deployment of molecular analysis tools in Gryllus. PMID:23671567
Teriakidis, Adrianna; Willshaw, David J; Ribchester, Richard R
2012-10-01
During development, neurons form supernumerary synapses, most of which are selectively pruned leading to stereotyped patterns of innervation. During the development of skeletal muscle innervation, or its regeneration after nerve injury, each muscle fiber is transiently innervated by multiple motor axon branches but eventually by a single branch. The selective elimination of all but one branch is the result of competition between the converging arbors. It is thought that motor neurons initially innervate muscle fibers randomly, but that axon branches from the same neuron (sibling branches) do not converge to innervate the same muscle fiber. However, random innervation would result in many neonatal endplates that are co-innervated by sibling branches. To investigate whether this occurs we examined neonatal levator auris longus (LAL) and 4th deep lumbrical (4DL) muscles, as well as adult reinnervated deep lumbrical muscles (1-4) in transgenic mice expressing yellow fluorescent protein (YFP) as a reporter. We provide direct evidence of convergence of sibling neurites within single fluorescent motor units, both during development and during regeneration after nerve crush. The incidence of sibling neurite convergence was 40% lower in regeneration and at least 75% lower during development than expected by chance. Therefore, there must be a mechanism that decreases the probability of its occurrence. As sibling neurite convergence is not seen in normal adults, or at later timepoints in regeneration, synapse elimination must also remove convergent synaptic inputs derived from the same motor neuron. Mechanistic theories of synaptic competition should now accommodate this form of isoaxonal plasticity. Copyright © 2012 Wiley Periodicals, Inc.
Mending the Butterfly: The New Historicism and Keats's "Eve of St. Agnes."
ERIC Educational Resources Information Center
Banerjee, Jacqueline
1995-01-01
Argues that among the branches of historicism practiced by literary critics today, a branch of New Historicism that is broadly humanistic as opposed to narrowly political is the most illuminating. Describes the development and theoretical premises of this branch. Shows how it may be applied to the analysis of a literary work such as Keats's…
2014-03-01
ADMINISTRATIVE INFORMATION The work described in this report was performed by the Unmanned Systems Science & Technology Branch (Code 71710) and the...Unmanned Systems Advanced Development Branch (Code 71720), Space and Naval Warfare Systems Center Pacific (SSC Pacific), San Diego, CA, and the Air...Earth™ is a trademark of Google Inc. Released by T. Pastore, Head Unmanned Systems Science & Technology Branch Under authority of A. D
Artificial Intelligence Research Branch future plans
NASA Technical Reports Server (NTRS)
Stewart, Helen (Editor)
1992-01-01
This report contains information on the activities of the Artificial Intelligence Research Branch (FIA) at NASA Ames Research Center (ARC) in 1992, as well as planned work in 1993. These activities span a range from basic scientific research through engineering development to fielded NASA applications, particularly those applications that are enabled by basic research carried out in FIA. Work is conducted in-house and through collaborative partners in academia and industry. All of our work has research themes with a dual commitment to technical excellence and applicability to NASA short, medium, and long-term problems. FIA acts as the Agency's lead organization for research aspects of artificial intelligence, working closely with a second research laboratory at the Jet Propulsion Laboratory (JPL) and AI applications groups throughout all NASA centers. This report is organized along three major research themes: (1) Planning and Scheduling: deciding on a sequence of actions to achieve a set of complex goals and determining when to execute those actions and how to allocate resources to carry them out; (2) Machine Learning: techniques for forming theories about natural and man-made phenomena; and for improving the problem-solving performance of computational systems over time; and (3) Research on the acquisition, representation, and utilization of knowledge in support of diagnosis design of engineered systems and analysis of actual systems.
Suárez-Ulloa, Victoria; Fernández-Tajes, Juan; Manfrin, Chiara; Gerdol, Marco; Venier, Paola; Eirín-López, José M.
2013-01-01
The extraordinary progress experienced by sequencing technologies and bioinformatics has made the development of omic studies virtually ubiquitous in all fields of life sciences nowadays. However, scientific attention has been quite unevenly distributed throughout the different branches of the tree of life, leaving molluscs, one of the most diverse animal groups, relatively unexplored and without representation within the narrow collection of well established model organisms. Within this Phylum, bivalve molluscs play a fundamental role in the functioning of the marine ecosystem, constitute very valuable commercial resources in aquaculture, and have been widely used as sentinel organisms in the biomonitoring of marine pollution. Yet, it has only been very recently that this complex group of organisms became a preferential subject for omic studies, posing new challenges for their integrative characterization. The present contribution aims to give a detailed insight into the state of the art of the omic studies and functional information analysis of bivalve molluscs, providing a timely perspective on the available data resources and on the current and prospective applications for the biomonitoring of harmful marine compounds. PMID:24189277
Miyawaki, Makoto
2006-12-01
Human anatomy texts state that the anterior cutaneous branch of the first intercostal nerve (Rca-Th1) does not exist or that, even if it does, it is poorly developed. However, an anterior cutaneous branch in the first intercostal space (Rca-1) was observed in 74.8% of cases examined (104/139 sides) and was not poorly developed at all. Some of the observed Rca-I were even larger than the anterior cutaneous branches in the second intercostal space (Rca-ll). The segment of origin of the Rca-I was analyzed in 37 sides and 66.2% (49/74 branches) were confirmed to be from Th1. As a result, in contrast with traditional beliefs, it was shown that Rca-Th1 exists. The Rca-I was classified into two types according to the course and distribution: (i) an anterior cutaneous branch that appeared at the anterior end of the first intercostal space (ICS), ran through the pectoralis major muscle and extended in the first ICS (Rca-1); and (ii) another branch that appeared at the same place but ran downward along the anterior surface of the second costal cartilage, deep to the pectoralis major muscle, to reach the inferior edge of the second costal cartilage or the second ICS, passed through the pectoralis major muscle and extended to the second rib or the second ICS (pseudo Rca-2). It was found that 77.8% (35/45 branches) of Rca-1 and 48.3% (14/29 branches) of pseudo Rca-2 were derived from Th1. Accordingly, the author suggests that the description in human anatomy texts should be revised to read, '... the Rca-Th1 exists quite constantly and some of appear at a position resembling Rca-Th2'.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hoven, Andor F. van den, E-mail: a.f.vandenhoven@umcutrecht.nl; Leeuwen, Maarten S. van, E-mail: m.s.vanleeuwen@umcutrecht.nl; Lam, Marnix G. E. H., E-mail: m.lam@umcutrecht.nl
PurposeCurrent anatomical classifications do not include all variants relevant for radioembolization (RE). The purpose of this study was to assess the individual hepatic arterial configuration and segmental vascularization pattern and to develop an individualized RE treatment strategy based on an extended classification.MethodsThe hepatic vascular anatomy was assessed on MDCT and DSA in patients who received a workup for RE between February 2009 and November 2012. Reconstructed MDCT studies were assessed to determine the hepatic arterial configuration (origin of every hepatic arterial branch, branching pattern and anatomical course) and the hepatic segmental vascularization territory of all branches. Aberrant hepatic arteries weremore » defined as hepatic arterial branches that did not originate from the celiac axis/CHA/PHA. Early branching patterns were defined as hepatic arterial branches originating from the celiac axis/CHA.ResultsThe hepatic arterial configuration and segmental vascularization pattern could be assessed in 110 of 133 patients. In 59 patients (54 %), no aberrant hepatic arteries or early branching was observed. Fourteen patients without aberrant hepatic arteries (13 %) had an early branching pattern. In the 37 patients (34 %) with aberrant hepatic arteries, five also had an early branching pattern. Sixteen different hepatic arterial segmental vascularization patterns were identified and described, differing by the presence of aberrant hepatic arteries, their respective vascular territory, and origin of the artery vascularizing segment four.ConclusionsThe hepatic arterial configuration and segmental vascularization pattern show marked individual variability beyond well-known classifications of anatomical variants. We developed an individualized RE treatment strategy based on an extended anatomical classification.« less
1987-11-16
technologi- cal engineering, and design in the subordinate units and takes steps to pro- vide them with necessary technical-material resources; b) It... methodologies and the uniform standards and norms for the branch, subbranches, and other activities, and oversees their manner of application; it...dual subordination, in the field of preparing and fulfilling the annual plans for research, design , and microproduction; f) It participates in the
Surface water supply of the United States, 1907-8, Part III. Ohio River Basin
,
1910-01-01
This volume contains results of flow measurements made on certain streams in the United States. The work was performed by the water-resources branch of the United States Geological Survey, either independently or in cooperation with organizations mentioned herein. These investigations are authorized by the organic law of the Geological Survey (Stat. L., vol. 20, p. 394)...
The History of the Discovery of Blood Circulation: Unrecognized Contributions of Ayurveda Masters
ERIC Educational Resources Information Center
Patwardhan, Kishor
2012-01-01
Ayurveda, the native healthcare system of India, is a rich resource of well-documented ancient medical knowledge. Although the roots of this knowledge date back to the Vedic and post-Vedic eras, it is generally believed that a dedicated branch for healthcare was gradually established approximately between 400 BCE and 200 CE. Probably because the…
Hydrology and erosion impacts of mining derived coastal sand dunes, Chanaral Bay, Chile
Daniel G. Neary; Pablo Garcia-Chevesich
2008-01-01
Chile has an economy strongly based on the exploitation of its natural resources. Copper mining represents the main export monetary income, employing thousands of people all along the country. The Chilean Copper Corporation (CODELCO), El Salvador branch, has been the primary mining company, but it will be ending most of its activities by 2011 unless copper prices stay...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-15
... Human Resources and Housing Branch, New Executive Office Building, Room 10235, Washington, DC 20503 (202... appellant and the BVA must be informed so that the appellant's rights may be adequately protected and so... required by basic Constitutional due-process and by Title 38 U.S.C. 7107(b). From time to time, hearing...
The effect of Pb addition on the morphology of CdSe quantum dot
NASA Astrophysics Data System (ADS)
Kim, Young-Kuk; Cho, Young-Sang; Chung, Kookchae; Choi, Chul-Jin
2010-08-01
CdSe quantum dots had been synthesized with a hot injection method. It was shown that the addition of Pb ions in the initial precursor solution changed the morphology of CdSe nanocrystals from slightly prolate ellipsoid to branched rod. Photoluminescence (PL) of the branched nanocrystals showed rapid depression of emission intensity due to the morphological development to the branched nanocrystal induced by Pb addition. Low temperature PL spectrum indicated that the surface recombination of charge carrier resulted in the large depression of emission from the branched nanocrystal.
Overview of the Advanced High Frequency Branch
NASA Technical Reports Server (NTRS)
Miranda, Felix A.
2015-01-01
This presentation provides an overview of the competencies, selected areas of research and technology development activities, and current external collaborative efforts of the NASA Glenn Research Center's Advanced High Frequency Branch.
EVALUATING HYDROLOGICAL RESPONSE TO ...
Studies of future management and policy options based on different assumptions provide a mechanism to examine possible outcomes and especially their likely benefits or consequences. Planning and assessment in land and water resource management are evolving toward complex, spatially explicit regional assessments. These problems have to be addressed with distributed models that can compute runoff and erosion at different spatial and temporal scales. The extensive data requirements and the difficult task of building input parameter files, however, have long been an obstacle to the timely and cost-effective use of such complex models by resource managers. The U.S. EPA Landscape Ecology Branch in collaboration with the USDA-ARS Southwest Watershed Research Center has developed a geographic information system (GIS) tool to facilitate this process. A GIS provides the framework within which spatially distributed data are collected and used to prepare model input files, and model results are evaluated. The Automated Geospatial Watershed Assessment (AGWA) tool uses widely available standardized spatial datasets that can be obtained via the internet at no cost to the user. The data are used to develop input parameter files for KINEROS2 and SWAT, two watershed runoff and erosion simulation models that operate at different spatial and temporal scales. AGWA automates the process of transforming digital data into simulation model results and provides a visualization tool
2011 Military Family Life Project (MFLP): Tabulations of Responses
2012-06-30
officials contributing to the development of this survey included Cathy Flynn and Yuko Whitestone (Military Community and Family Policy). DMDC’s Survey...Design, Analysis & Operations Branch, under the guidance of Lindsay Rock, Acting Branch Chief, is responsible for the development of questionnaires...responsible for developing the sampling and weighting methods used in the survey program. Fawzi Al Nassir, SRA International, Inc., supervised the
NASA Astrophysics Data System (ADS)
Zhu, Xiaolu; Yang, Hao
2017-12-01
The recently emerged four-dimensional (4D) biofabrication technique aims to create dynamic three-dimensional (3D) biological structures that can transform their shapes or functionalities with time when an external stimulus is imposed or when cell postprinting self-assembly occurs. The evolution of 3D pattern of branching geometry via self-assembly of cells is critical for 4D biofabrication of artificial organs or tissues with branched geometry. However, it is still unclear that how the formation and evolution of these branching pattern are biologically encoded. We study the 4D fabrication of lung branching structures utilizing a simulation model on the reaction-diffusion mechanism, which is established using partial differential equations of four variables, describing the reaction and diffusion process of morphogens with time during the development process of lung branching. The simulation results present the forming process of 3D branching pattern, and also interpret the behaviors of side branching and tip splitting as the stalk growing, through 3D visualization of numerical simulation.
Wind-Induced Reconfigurations in Flexible Branched Trees
NASA Astrophysics Data System (ADS)
Ojo, Oluwafemi; Shoele, Kourosh
2017-11-01
Wind induced stresses are the major mechanical cause of failure in trees. We know that the branching mechanism has an important effect on the stress distribution and stability of a tree in the wind. Eloy in PRL 2011, showed that Leonardo da Vinci's original observation which states the total cross section of branches is conserved across branching nodes is the best configuration for resisting wind-induced fracture in rigid trees. However, prediction of the fracture risk and pattern of a tree is also a function of their reconfiguration capabilities and how they mitigate large wind-induced stresses. In this studies through developing an efficient numerical simulation of flexible branched trees, we explore the role of the tree flexibility on the optimal branching. Our results show that the probability of a tree breaking at any point depends on both the cross-section changes in the branching nodes and the level of tree flexibility. It is found that the branching mechanism based on Leonardo da Vinci's original observation leads to a uniform stress distribution over a wide range of flexibilities but the pattern changes for more flexible systems.
Rosenbaum, M B; Girotti, L A; Lázzari, J O; Halpern, M S; Elizari, M V
1982-01-01
In five cases of anteroseptal myocardial infarction complicated by intermittent right bundle-branch block, the onset of right bundle-branch block provoked the appearance of abnormal Q waves in leads V1 and V2, whereas a small initial R wave was present in the same leads during normal conduction. The intermittency of the conduction disturbance indicated that the Q waves were "right bundle-branch block dependent". It was also apparent that right bundle-branch block shifted the electrical location of the infarct towards the right, and made it look much larger. Right bundle-branch block dependent Q waves may arise during the acute stage of an anterior infarct suggesting, fallaciously, that an acute extension has occurred, or during the chronic stage, leading to the erroneous supposition that a new infarct had developed. The abnormal Q waves anteroseptal infarction complicated by fixed right bundle-branch block, though obviously related to the infarct, may be dependent on the right bundle-branch block. PMID:7059400
Takahashi, Toshiaki; Friedmacher, Florian; Zimmer, Julia; Puri, Prem
2017-02-01
Pulmonary hypoplasia (PH), characterized by smaller lung size and reduced airway branching, remains a major therapeutic challenge in newborns with congenital diaphragmatic hernia (CDH). T-box transcription factors (Tbx) have been identified as key components of the gene network that regulates fetal lung development. Tbx2, Tbx4 and Tbx5 are expressed throughout the mesenchyme of the developing lung, regulating the process of lung branching morphogenesis. Furthermore, lungs of Tbx2-, Tbx4- and Tbx5-deficient mice are hypoplastic and exhibit decreased lung branching, similar to PH in human CDH. We hypothesized that the expression of Tbx2, Tbx4 and Tbx5 is decreased in the branching airway mesenchyme of hypoplastic rat lungs with nitrofen-induced CDH. Time-mated rats received either nitrofen or vehicle on gestational day 9 (D9). Fetuses were killed on D15, D18 and D21, and dissected lungs were divided into control and nitrofen-exposed specimens. Pulmonary gene expression of Tbx2, Tbx4 and Tbx5 was investigated by quantitative real-time polymerase chain reaction. Immunofluorescence double staining for Tbx2, Tbx4 and Tbx5 was combined with the mesenchymal marker Fgf10 to assess protein expression and localization in branching airway tissue. Relative mRNA levels of Tbx2, Tbx4 and Tbx5 were significantly reduced in lungs of nitrofen-exposed fetuses on D15, D18 and D21 compared to controls. Confocal laser scanning microscopy showed markedly diminished immunofluorescence of Tbx2, Tbx4 and Tbx5 in mesenchymal cells surrounding branching airways of nitrofen-exposed fetuses on D15, D18 and D21 compared to controls. Decreased expression of Tbx2, Tbx4 and Tbx5 in the pulmonary mesenchyme during fetal lung development may lead to a decrease or arrest of airway branching, thus contributing to PH in the nitrofen-induced CDH model.
OsRAMOSA2 Shapes Panicle Architecture through Regulating Pedicel Length.
Lu, Huan; Dai, Zhengyan; Li, Ling; Wang, Jiang; Miao, Xuexia; Shi, Zhenying
2017-01-01
The panicle architecture of rice is an important characteristic that influences reproductive success and yield. It is largely determined by the number and length of the primary and secondary branches. The number of panicle branches is defined by the inflorescence meristem state between determinacy and indeterminacy; for example, the maize ramosa2 ( ra2 ) mutant has more branches in its tassel through loss of spikelet determinacy. Some genes and factors influencing the number of primary and secondary branches have been studied, but little is known about the molecular mechanism underlying pedicel development, which also influences panicle architecture. We report here that rice OsRAMOSA2 ( OsRA2 ) gene modifies panicle architecture through regulating pedicel length. Ectopic expression of OsRA2 resulted in a shortened pedicel while inhibition of OsRA2 through RNA interference produced elongated pedicel. In addition, OsRA2 influenced seed morphology. The OsRA2 protein localized to the nucleus and showed transcriptional activation in yeast; in accordance with its function in pedicel development, OsRA2 mRNA was enriched in the anlagen of axillary meristems, such as primary and secondary branch meristems and the spikelet meristems of young panicles. This indicates a conserved role of OsRA2 for shaping the initial steps of inflorescence architecture. Genetic analysis revealed that OsRA2 may control panicle architecture using the same pathway as that of the axillary meristem gene LAX1 ( LAX PANICLE1 ). Moreover, OsRA2 acted downstream of RCN2 in regulating pedicel and branch lengths, but upstream of RCN2 for control of the number of secondary branches, indicating that branch number and length development in the panicle were respectively regulated using parallel pathway. Functional conservation between OsRA2 and AtLOB , and the conservation and diversification of RA2 in maize and rice are also discussed.
The Specific Features of design and process engineering in branch of industrial enterprise
NASA Astrophysics Data System (ADS)
Sosedko, V. V.; Yanishevskaya, A. G.
2017-06-01
Production output of industrial enterprise is organized in debugged working mechanisms at each stage of product’s life cycle from initial design documentation to product and finishing it with utilization. The topic of article is mathematical model of the system design and process engineering in branch of the industrial enterprise, statistical processing of estimated implementation results of developed mathematical model in branch, and demonstration of advantages at application at this enterprise. During the creation of model a data flow about driving of information, orders, details and modules in branch of enterprise groups of divisions were classified. Proceeding from the analysis of divisions activity, a data flow, details and documents the state graph of design and process engineering was constructed, transitions were described and coefficients are appropriated. To each condition of system of the constructed state graph the corresponding limiting state probabilities were defined, and also Kolmogorov’s equations are worked out. When integration of sets of equations of Kolmogorov the state probability of system activity the specified divisions and production as function of time in each instant is defined. On the basis of developed mathematical model of uniform system of designing and process engineering and manufacture, and a state graph by authors statistical processing the application of mathematical model results was carried out, and also advantage at application at this enterprise is shown. Researches on studying of loading services probability of branch and third-party contractors (the orders received from branch within a month) were conducted. The developed mathematical model of system design and process engineering and manufacture can be applied to definition of activity state probability of divisions and manufacture as function of time in each instant that will allow to keep account of loading of performance of work in branches of the enterprise.
AGU President's Message: Obama Administration's Commitment to Scientific Integrity
NASA Astrophysics Data System (ADS)
McPhaden, Michael J.
2011-01-01
In March 2009, President Barack Obama issued a memorandum on the subject of scientific integrity in which he stated emphatically, 'Science and the scientific process must inform and guide decisions of my Administration on a wide range of issues, including improvement of public health, protection of the environment, increased efficiency in the use of energy and other resources, mitigation of the threat of climate change, and protection of national security.” The president charged John Holdren, director of the Office of Science and Technology Policy (OSTP), with developing specific recommendations “for ensuring the highest level of integrity in all aspects of the executive branch's involvement with scientific and technological processes.” On Friday, 17 December, OSTP released federal department and agency guidelines for implementing the administration’s policies on scientific integrity.
Jia, Wen-Jun; Jiang, Shan; Tang, Qiao-Li; Shen, Di; Xue, Bin; Ning, Wen; Li, Chao-Jun
2016-06-01
G proteins play essential roles in regulating fetal lung development, and any defects in their expression or function (eg, activation or posttranslational modification) can lead to lung developmental malformation. Geranylgeranyl diphosphate synthase (GGPPS) can modulate protein prenylation that is required for protein membrane-anchoring and activation. Here, we report that GGPPS regulates fetal lung branching morphogenesis possibly through controlling K-Ras prenylation during fetal lung development. GGPPS was continuously expressed in lung epithelium throughout whole fetal lung development. Specific deletion of geranylgeranyl diphosphate synthase 1 (Ggps1) in lung epithelium during fetal lung development resulted in neonatal respiratory distress syndrome-like disease. The knockout mice died at postnatal day 1 of respiratory failure, and the lungs showed compensatory pneumonectasis, pulmonary atelectasis, and hyaline membranes. Subsequently, we proved that lung malformations in Ggps1-deficient mice resulted from the failure of fetal lung branching morphogenesis. Further investigation revealed Ggps1 deletion blocked K-Ras geranylgeranylation and extracellular signal-related kinase 1 or 2/mitogen-activated protein kinase signaling, which in turn disturbed fibroblast growth factor 10 regulation on fetal lung branching morphogenesis. Collectively, our data suggest that GGPPS is essential for maintaining fetal lung branching morphogenesis, which is possibly through regulating K-Ras prenylation. Copyright © 2016 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.
6-O-Branched Oligo-β-glucan-Based Antifungal Glycoconjugate Vaccines.
Liao, Guochao; Zhou, Zhifang; Liao, Jun; Zu, Luning; Wu, Qiuye; Guo, Zhongwu
2016-02-12
With the rapid growth in fungal infections and drug-resistant fungal strains, antifungal vaccines have become an especially attractive strategy to tackle this important health problem. β-Glucans, a class of extracellular carbohydrate antigens abundantly and consistently expressed on fungal cell surfaces, are intriguing epitopes for antifungal vaccine development. β-Glucans have a conserved β-1,3-glucan backbone with sporadic β-1,3- or β-1,6-linked short glucans as branches at the 6-O-positions, and the branches may play a critical role in their immunologic functions. To study the immunologic properties of branched β-glucans and develop β-glucan-based antifungal vaccines, three branched β-glucan oligosaccharides with 6-O-linked β-1,6-tetraglucose, β-1,3-diglucose, and β-1,3-tetraglucose branches on a β-1,3-nonaglucan backbone, which mimic the structural epitopes of natural β-glucans, were synthesized and coupled with keyhole limpet hemocyanin (KLH) to form novel synthetic conjugate vaccines. These glycoconjugates were proved to elicit strong IgG antibody responses in mice. It was also discovered that the number, size, and structure of branches linked to the β-glucan backbone had a significant impact on the immunologic property. Moreover, antibodies induced by the synthetic oligosaccharide-KLH conjugates were able to recognize and bind to natural β-glucans and fungal cells. Most importantly, these conjugates elicited effective protection against systemic Candida albicans infection in mice. Thus, branched oligo-β-glucans were identified as functional epitopes for antifungal vaccine design and the corresponding protein conjugates as promising antifungal vaccine candidates.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-06
..., Energy Branch, Attention: BioRefinery Assistance Program, 1400 Independence Avenue, SW., STOP 3225... to USDA's Rural Development National Office: Energy Branch, Attention: BioRefinery Assistance Program...
Chen, Xingxing; Zhang, Zijian; Ding, Zicheng; Liu, Jun; Wang, Lixiang
2016-08-22
Conjugated polymers are essential for solution-processable organic opto-electronic devices. In contrast to the great efforts on developing new conjugated polymer backbones, research on developing side chains is rare. Herein, we report branched oligo(ethylene glycol) (OEG) as side chains of conjugated polymers. Compared with typical alkyl side chains, branched OEG side chains endowed the resulting conjugated polymers with a smaller π-π stacking distance, higher hole mobility, smaller optical band gap, higher dielectric constant, and larger surface energy. Moreover, the conjugated polymers with branched OEG side chains exhibited outstanding photovoltaic performance in polymer solar cells. A power conversion efficiency of 5.37 % with near-infrared photoresponse was demonstrated and the device performance could be insensitive to the active layer thickness. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Development of Internet algorithms and some calculations of power plant COP
NASA Astrophysics Data System (ADS)
Ustjuzhanin, E. E.; Ochkov, V. F.; Znamensky, V. E.
2017-11-01
The authors have analyzed Internet resources containing information on some thermodynamic properties of technically important substances (the water, the air etc.). There are considered databases those possess such resources and are hosted in organizations (Joint Institute for High Temperatures (Russian Academy of Sciences), Standartinform (Russia), National Institute of Standards and Technology (USA), Institute for Thermal Physics (Siberian Branch of the Russian Academy of Sciences), etc.). Currently, a typical form is an Internet resource that includes a text file, for example, it is a file containing tabulated properties, R = (ρ, s, h…), here ρ - the density, s - the entropy, h - the enthalpy of a substance. It is known a small number of Internet resources those have the following characteristic. The resource allows a customer to realize a number of options, for example: i) to enter the input data, Y = (p, T), here p - the pressure, T - the temperature, ii) to calculate R property using “an exe-file” program, iii) to copy the result X = (p, T, ρ, h, s, …). Recently, some researchers (including the authors of this report) have requested a software (SW) that is designed for R property calculations and has a form of an open interactive (OI) Internet resource (“a client function”, “template”). A computing part of OI resource is linked: 1) with a formula, which is applied to calculate R property, 2) with a Mathcad program, Code_1(R,Y). An interactive part of OI resource is based on Informatics and Internet technologies. We have proposed some methods and tools those are related to this part and let us: a) to post OI resource on a remote server, b) to link a client PC with the remote server, c) to implement a number of options to clients. Among these options, there are: i) to calculate R property at given Y arguments, ii) to copy mathematical formulas, iii) to copy Code_1(R,Y) as a whole. We have developed some OI - resources those are focused on sharing: a) SW that is used to design power plants, for an example, Code - GTP_1(Z,R,Y) and b) client functions those are aimed to determine R properties of the working fluid at fixed points of the thermodynamic cycle. The program let us calculate energy criteria, Z, including the internal coefficient of performance (COP) for a power plant. We have discussed OI resources, among them OI resource that includes Code - GTP_1(Z,R,Y) and connected with a complex power plant included: i) several gas turbines, i) several compressors etc.
NASA Technical Reports Server (NTRS)
Short, Nick, Jr.; Bedet, Jean-Jacques; Bodden, Lee; Boddy, Mark; White, Jim; Beane, John
1994-01-01
The Goddard Space Flight Center (GSFC) Distributed Active Archive Center (DAAC) has been operational since October 1, 1993. Its mission is to support the Earth Observing System (EOS) by providing rapid access to EOS data and analysis products, and to test Earth Observing System Data and Information System (EOSDIS) design concepts. One of the challenges is to ensure quick and easy retrieval of any data archived within the DAAC's Data Archive and Distributed System (DADS). Over the 15-year life of EOS project, an estimated several Petabytes (10(exp 15)) of data will be permanently stored. Accessing that amount of information is a formidable task that will require innovative approaches. As a precursor of the full EOS system, the GSFC DAAC with a few Terabits of storage, has implemented a prototype of a constraint-based task and resource scheduler to improve the performance of the DADS. This Honeywell Task and Resource Scheduler (HTRS), developed by Honeywell Technology Center in cooperation the Information Science and Technology Branch/935, the Code X Operations Technology Program, and the GSFC DAAC, makes better use of limited resources, prevents backlog of data, provides information about resources bottlenecks and performance characteristics. The prototype which is developed concurrently with the GSFC Version 0 (V0) DADS, models DADS activities such as ingestion and distribution with priority, precedence, resource requirements (disk and network bandwidth) and temporal constraints. HTRS supports schedule updates, insertions, and retrieval of task information via an Application Program Interface (API). The prototype has demonstrated with a few examples, the substantial advantages of using HTRS over scheduling algorithms such as a First In First Out (FIFO) queue. The kernel scheduling engine for HTRS, called Kronos, has been successfully applied to several other domains such as space shuttle mission scheduling, demand flow manufacturing, and avionics communications scheduling.
The moduli space of vacua of $$ \\mathcal{N}=2 $$ class $$ \\mathcal{S} $$ theories
DOE Office of Scientific and Technical Information (OSTI.GOV)
Xie, Dan; Yonekura, Kazuya
We develop a systematic method to describe the moduli space of vacua of four dimensional N=2 class S theories including Coulomb branch, Higgs branch and mixed branches. In particular, we determine the Higgs and mixed branch roots, and the dimensions of the Coulomb and Higgs components of mixed branches. They are derived by using generalized Hitchin’s equations obtained from twisted compactification of 5d maximal Super-Yang-Mills, with local degrees of freedom at punctures given by (nilpotent) orbits. The crucial thing is the holomorphic factorization of the Seiberg-Witten curve and reduction of singularity at punctures. We illustrate our method by many examplesmore » including N=2 SQCD, T N theory and Argyres-Douglas theories.« less
Yamada, Aya; Futagi, Masaharu; Fukumoto, Emiko; Saito, Kan; Yoshizaki, Keigo; Ishikawa, Masaki; Arakaki, Makiko; Hino, Ryoko; Sugawara, Yu; Ishikawa, Momoko; Naruse, Masahiro; Miyazaki, Kanako; Nakamura, Takashi; Fukumoto, Satoshi
2016-01-01
Cell-cell interaction via the gap junction regulates cell growth and differentiation, leading to formation of organs of appropriate size and quality. To determine the role of connexin43 in salivary gland development, we analyzed its expression in developing submandibular glands (SMGs). Connexin43 (Cx43) was found to be expressed in salivary gland epithelium. In ex vivo organ cultures of SMGs, addition of the gap junctional inhibitors 18α-glycyrrhetinic acid (18α-GA) and oleamide inhibited SMG branching morphogenesis, suggesting that gap junctional communication contributes to salivary gland development. In Cx43−/− salivary glands, submandibular and sublingual gland size was reduced as compared with those from heterozygotes. The expression of Pdgfa, Pdgfb, Fgf7, and Fgf10, which induced branching of SMGs in Cx43−/− samples, were not changed as compared with those from heterozygotes. Furthermore, the blocking peptide for the hemichannel and gap junction channel showed inhibition of terminal bud branching. FGF10 induced branching morphogenesis, while it did not rescue the Cx43−/− phenotype, thus Cx43 may regulate FGF10 signaling during salivary gland development. FGF10 is expressed in salivary gland mesenchyme and regulates epithelial proliferation, and was shown to induce ERK1/2 phosphorylation in salivary epithelial cells, while ERK1/2 phosphorylation in HSY cells was dramatically inhibited by 18α-GA, a Cx43 peptide or siRNA. On the other hand, PDGF-AA and PDGF-BB separately induced ERK1/2 phosphorylation in primary cultured salivary mesenchymal cells regardless of the presence of 18α-GA. Together, our results suggest that Cx43 regulates FGF10-induced ERK1/2 phosphorylation in salivary epithelium but not in mesenchyme during the process of SMG branching morphogenesis. PMID:26565022
Nock, Charles A; Lecigne, Bastien; Taugourdeau, Olivier; Greene, David F; Dauzat, Jean; Delagrange, Sylvain; Messier, Christian
2016-06-01
Despite a longstanding interest in variation in tree species vulnerability to ice storm damage, quantitative analyses of the influence of crown structure on within-crown variation in ice accretion are rare. In particular, the effect of prior interception by higher branches on lower branch accumulation remains unstudied. The aim of this study was to test the hypothesis that intra-crown ice accretion can be predicted by a measure of the degree of sheltering by neighbouring branches. Freezing rain was artificially applied to Acer platanoides L., and in situ branch-ice thickness was measured directly and from LiDAR point clouds. Two models of freezing rain interception were developed: 'IceCube', which uses point clouds to relate ice accretion to a voxel-based index (sheltering factor; SF) of the sheltering effect of branch elements above a measurement point; and 'IceTree', a simulation model for in silico evaluation of the interception pattern of freezing rain in virtual tree crowns. Intra-crown radial ice accretion varied strongly, declining from the tips to the bases of branches and from the top to the base of the crown. SF for branches varied strongly within the crown, and differences among branches were consistent for a range of model parameters. Intra-crown variation in ice accretion on branches was related to SF (R(2) = 0·46), with in silico results from IceTree supporting empirical relationships from IceCube. Empirical results and simulations confirmed a key role for crown architecture in determining intra-crown patterns of ice accretion. As suspected, the concentration of freezing rain droplets is attenuated by passage through the upper crown, and thus higher branches accumulate more ice than lower branches. This is the first step in developing a model that can provide a quantitative basis for investigating intra-crown and inter-specific variation in freezing rain damage. © The Author 2016. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Ando, Toshiya; Fujiwara, Haruhiko; Kojima, Tetsuya
2018-01-25
Antennae are multi-segmented appendages and main odor-sensing organs in insects. In Lepidoptera (moths and butterflies), antennal morphologies have diversified according to their ecological requirements. While diurnal butterflies have simple, rod-shaped antennae, nocturnal moths have antennae with protrusions or lateral branches on each antennal segment for high-sensitive pheromone detection. A previous study on the Bombyx mori (silk moth) antenna, forming two lateral branches per segment, during metamorphosis has revealed the dramatic change in expression of antennal patterning genes to segmentally reiterated, branch-associated pattern and abundant proliferation of cells contributing almost all the dorsal half of the lateral branch. Thus, localized cell proliferation possibly controlled by the branch-associated expression of antennal patterning genes is implicated in lateral branch formation. Yet, actual gene function in lateral branch formation in Bombyx mori and evolutionary mechanism of various antennal morphologies in Lepidoptera remain elusive. We investigated the function of several genes and signaling specifically in lateral branch formation in Bombyx mori by the electroporation-mediated incorporation of siRNAs or morpholino oligomers. Knock down of aristaless, a homeobox gene expressed specifically in the region of abundant cell proliferation within each antennal segment, during metamorphosis resulted in missing or substantial shortening of lateral branches, indicating its importance for lateral branch formation. aristaless expression during metamorphosis was lost by knock down of Distal-less and WNT signaling but derepressed by knock down of Notch signaling, suggesting the strict determination of the aristaless expression domain within each antennal segment by the combinatorial action of them. In addition, analyses of pupal aristaless expression in antennae with various morphologies of several lepidopteran species revealed that the aristaless expression pattern has a striking correlation with antennal shapes, whereas the segmentally reiterated expression pattern was observed irrespective of antennal morphologies. Our results presented here indicate the significance of aristaless function in lateral branch formation in B. mori and imply that the diversification in the aristaless expression pattern within each antennal segment during metamorphosis is one of the significant determinants of antennal morphologies. According to these findings, we propose a mechanism underlying development and evolution of lepidopteran antennae with various morphologies.
Seldal, Tarald; Hegland, Stein Joar; Rydgren, Knut; Rodriguez-Saona, Cesar; Töpper, Joachim Paul
2017-03-01
Inducible plant defense is a beneficial strategy for plants, which imply that plants should allocate resources from growth and reproduction to defense when herbivores attack. Plant ecologist has often studied defense responses in wild populations by biomass clipping experiments, whereas laboratory and greenhouse experiments in addition apply chemical elicitors to induce defense responses. To investigate whether field ecologists could benefit from methods used in laboratory and greenhouse studies, we established a randomized block-design in a pine-bilberry forest in Western Norway. We tested whether we could activate defense responses in bilberry ( Vaccinium myrtillus ) by nine different treatments using clipping (leaf tissue or branch removal) with or without chemical treatment by methyljasmonate (MeJA). We subsequently measured consequences of induced defenses through vegetative growth and insect herbivory during one growing season. Our results showed that only MeJA-treated plants showed consistent defense responses through suppressed vegetative growth and reduced herbivory by leaf-chewing insects, suggesting an allocation of resources from growth to defense. Leaf tissue removal reduced insect herbivory equal to the effect of the MeJa treatments, but had no negative impact on growth. Branch removal did not reduce insect herbivory or vegetative growth. MeJa treatment and clipping combined did not give an additional defense response. In this study, we investigated how to induce defense responses in wild plant populations under natural field conditions. Our results show that using the chemical elicitor MeJA, with or without biomass clipping, may be a better method to induce defense response in field experiments than clipping of leaves or branches that often has been used in ecological field studies.
Putting science into action on Forest Service Lands [Chapter 5
William M. Block; Victoria A. Saab; Leonard Ruggiero
2012-01-01
The U.S. Forest Service includes three main branches: National Forest Systems, Research and Development, and State and Private Forestry. Herein, we focus on National Forest Systems and Research and Development. National Forest Systems is the management branch of the agency, and its charge is to administer national forests and grasslands throughout the United States. A...
The singularity structure of scale-invariant rank-2 Coulomb branches
NASA Astrophysics Data System (ADS)
Argyres, Philip C.; Long, Cody; Martone, Mario
2018-05-01
We compute the spectrum of scaling dimensions of Coulomb branch operators in 4d rank-2 N=2 superconformal field theories. Only a finite rational set of scaling dimensions is allowed. It is determined by using information about the global topology of the locus of metric singularities on the Coulomb branch, the special Kähler geometry near those singularities, and electric-magnetic duality monodromies along orbits of the U(1) R symmetry. A set of novel topological and geometric results are developed which promise to be useful for the study and classification of Coulomb branch geometries at all ranks.
1980-07-01
ANALYSES APPENDIX E - FIGURES APPENDIX F - GEOLOGY 1 v~i I LI PHASE I INSPECTION REPORT NATIONAL DAM INSPECTION PROGRAM LAKE JEAN DAM NDI# PA-00570...Red Rock, Pennsylvania, U.S.G.S. 7.5 minute topographic quadrangle (see Figure 1, Appendix E ). The coordinates of the dam are N41* 21.1’ and W76 0...3.1. e ). e . Ownership. Commonwealth of Pennsylvania Office of Resources Management Department of Environmental Resources P.O. Box 1467 Harrisburg
Reconnaissance of the water resources of the Lonesome Valley area, Yavapai County, Arizona
Metzger, Donald G.
1957-01-01
In accordance with a request from its cooperating agency, the Arizona State Land Department, the U.S. Geological Survey has made a brief reconnaissance of the water resources of the Lonesome Valley area, Yavapai County, Ariz., to determine the probable hydrologic effects of a proposed dam on Lynx Creek. The construction of this dam has been proposed by the Arizona Game and Fish Department, for recreational and fish-cultural purposes. Data on the geology of the area were furnished by Mrs. Medora M. Krieger, geologist, Geologic Division, U.S. Geological Survey, and the map was prepared by Floyd R. Twenter, geologist, Ground Water Branch.
Esipov, A V; Tsyganok, V A; Vartbaronov, R A
2012-10-01
The history of formation and development of branch No. 1 FSI "Main Military Clinical Hospital n. a. N.N.Burdenko of the Ministry of Defense of the RF" is described in the article. The hospital celebrates in this year the 65-years anniversary of scientific and medical activity in the field of military clinical medicine, aviation clinical medicine and a fight-surgeon's examination. The leading historical role of this establishment in support of flight safety, combat readiness and anti-aircraft rocket troops is shown, and then last 10 years and in Air Forces of Russia, and also the basic achievements of branch in successful scientific and medical activity from 1946 till present time are given. Prospects of the further development of this branch are substantially connected to the increase of intensification of research works together with leading military-medical establishments of an aviation profile: Institute of Military medicine of Military-medical Academy, the Central flight-surgeon commission and 3 branch of FSI "3 Central military Clinical Hospital MD RF" etc.,--in solution of the large state problem of decrease of accident rate and rising of a medical flight safety of the RF State aviation.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Konez, Orhan; Burrows, Patricia E.; Harmon, William E.
2001-09-15
A 13-year-old girl who recently developed hypertension was diagnosed to have an occluded right renal branch artery and was treated successfully with percutaneous transluminal angioplasty (PTA). To our knowledge, PTA has not been reported as a treatment for totally occluded renal branch arteries, and there is no data available regarding the success rate and possible complications.
James S. Meadows; J.C.G. Goelz; Daniel A. Skojac
2013-01-01
Epicormic branches are adventitious twigs that develop from dormant buds found along the main bole of hardwood trees. These buds may be released at any time during the life of the tree in response to various types of stimuli. Epicormic branches cause defects in the underlying wood and may cause significant reductions in both log grade and subsequent lumber value....
2016-10-01
BRIEFING CHARTS) D. Zeppettella Structures Technology Branch Aerospace Vehicles Division Steve Bucca and Thomas Gage BerrieHill Research...R. WIPPERMAN, Chief Program Manager Structures Technology Branch Structures Technology Branch Aerospace Vehicles Division Aerospace Vehicles...Corporation) 5d. PROJECT NUMBER 4920 5e. TASK NUMBER 5f. WORK UNIT NUMBER Q06A 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING
Sall1-dependent signals affect Wnt signaling and ureter tip fate to initiate kidney development.
Kiefer, Susan M; Robbins, Lynn; Stumpff, Kelly M; Lin, Congxing; Ma, Liang; Rauchman, Michael
2010-09-01
Development of the metanephric kidney depends on precise control of branching of the ureteric bud. Branching events represent terminal bifurcations that are thought to depend on unique patterns of gene expression in the tip compared with the stalk and are influenced by mesenchymal signals. The metanephric mesenchyme-derived signals that control gene expression at the ureteric bud tip are not well understood. In mouse Sall1 mutants, the ureteric bud grows out and invades the metanephric mesenchyme, but it fails to initiate branching despite tip-specific expression of Ret and Wnt11. The stalk-specific marker Wnt9b and the beta-catenin downstream target Axin2 are ectopically expressed in the mutant ureteric bud tips, suggesting that upregulated canonical Wnt signaling disrupts ureter branching in this mutant. In support of this hypothesis, ureter arrest is rescued by lowering beta-catenin levels in the Sall1 mutant and is phenocopied by ectopic expression of a stabilized beta-catenin in the ureteric bud. Furthermore, transgenic overexpression of Wnt9b in the ureteric bud causes reduced branching in multiple founder lines. These studies indicate that Sall1-dependent signals from the metanephric mesenchyme are required to modulate ureteric bud tip Wnt patterning in order to initiate branching.
Lim, Yong-beom; Mays, Charles E; Kim, Younghwan; Titlow, William B; Ryou, Chongsuk
2010-03-01
Branched polyamines are effective in inhibiting prions in a cationic surface charge density dependent manner. However, toxicity associated with branched polyamines, in general, often hampers the successful application of the compounds to treat prion diseases. Here, we report that constitutively maintained cationic properties in branched polyamines reduced the intrinsic toxicity of the compounds while retaining the anti-prion activities. In prion-infected neuroblastoma cells, quaternization of amines in polyethyleneimine (PEI) and polyamidoamine (PAMAM) dendrimers markedly increased the nontoxic concentration ranges of the compounds and still supported, albeit reduced, an appreciable level of anti-prion activity in clearing prions from the infected cells. Furthermore, quaternized PEI was able to degrade prions at acidic pH conditions and inhibit the in vitro prion propagation facilitated by conversion of the normal prion protein isoform to its misfolded counterpart, although such activities were decreased by quaternization. Quaternized PAMAM was least effective in degrading prions but efficiently inhibited prion conversion with the same efficacy as unmodified PAMAM. Our results suggest that quaternization represents an effective strategy for developing nontoxic branched polyamines with potent anti-prion activity. This study highlights the importance of polyamine structural control for developing polyamine-based anti-prion agents and understanding of an action mechanism of quaternized branched polyamines. Copyright (c) 2009 Elsevier Ltd. All rights reserved.
Nakamura, Yasunori; Ono, Masami; Sawada, Takayuki; Crofts, Naoko; Fujita, Naoko; Steup, Martin
2017-11-01
Functional interactions of plastidial phosphorylase (Pho1) and starch branching enzymes (BEs) from the developing rice endosperm are the focus of this study. In the presence of both Pho1 and BE, the same branched primer molecule is elongated and further branched almost simultaneously even at very low glucan concentrations present in the purified enzyme preparations. By contrast, in the absence of any BE, glucans are not, to any significant extent, elongated by Pho1. Based on our in vitro data, in the developing rice endosperm, Pho1 appears to be weakly associated with any of the BE isozymes. By using fluorophore-labeled malto-oligosaccharides, we identified maltose as the smallest possible primer for elongation by Pho1. Linear dextrins act as carbohydrate substrates for BEs. By functionally interacting with a BE, Pho1 performs two essential functions during the initiation of starch biosynthesis in the rice endosperm: First, it elongates maltodextrins up to a degree of polymerization of at least 60. Second, by closely interacting with BEs, Pho1 is able to elongate branched glucans efficiently and thereby synthesizes branched carbohydrates essential for the initiation of amylopectin biosynthesis. Copyright © 2017 Elsevier B.V. All rights reserved.
JT Bachman Leadership Framework
2017-07-01
has been reviewed by Mr. Ray E. Poff, Head, Missile Systems Engineering and Integration Branch (H33), and Mr. Steven L. Collignon, Head, Missile...promotes participation in the above mentioned resources will enhance the careers of individuals while accomplishing the mission goals of the organization...in which people seek to be accountable to themselves and their team members. As a leader, evaluate whether one’s career passion meshes with the
Surface water supply of the United States, 1907-8, Part IV. St. Lawrence River Basin
,
1910-01-01
This volume contains results of flow measurements made on certain streams in the United States. The work was performed by the water-resources branch of the United States Geological Survey, either independently or in cooperation with organizations mentioned herein. These investigations are authorized by the organic law of the Geological Survey (Stat. L., vol. 20, p. 394)...
Surface Water Records of Colorado
U.S. Geological Survey, Water Resources Division
1962-01-01
The surface-water records for the 1962 water year for gaging stations and miscellaneous sites within the State of Colorado are given in this report. For convenience there are also included records for a few pertinent gaging stations in bordering States. The records were collected and computed by the Water Resources Division of the U.S. Geological Survey, under the direction of J. W. Odell, district engineer, Surface Water Branch.
Study Guide for a Beginning Course in Ground-Water Hydrology: Part 1 -- Course Participants
1990-01-01
and Lonnquist, 1971 , fig. 7.) . . . . . . . . . . . . . . . . . . . . . . 99 Vector areas associated with branches in a square-mesh finite...water reservoir. (From Bennett and Giusti, 1971 .). 112 Location and general geographic features of Long Island, New York. (From Franke and...Techniques of Water- Resources Investigations of the U.S. Geological Survey, Book 2, Chapter Fl, 97 p. Stallman, R. W., 1971 , Aquifer-test design
Crown-rise and crown-length dynamics: applications to loblolly pine
Harry T. Valentine; Ralph L. Amateis; Jeffrey H. Gove; Annikki Makela
2013-01-01
The original crown-rise model estimates the average height of a crown-base in an even-aged mono-species stand of trees. We have elaborated this model to reduce bias and prediction error, and to also provide crown-base estimates for individual trees. Results for the latter agree with a theory of branch death based on resource availability and allocation.We use the...
2013-05-01
Agenda RAA Recovery Auditing Act SBR Statement of Budgetary Resources TMA TRICARE Management Activity USACE United States Army Corps of Engineers...Defense Authorization Act for Fiscal Year 2002 included the provisions commonly referred to as the Recovery Auditing Act ( RAA ).12...Administration, and Social Security Administration. The RAA required, among other things, that all executive branch agencies entering into contracts
Christensen, Victoria G.; Lee, Kathy E.; Sanocki, Christopher A.; Mohring, Eric H.; Kiesling, Richard L.
2009-01-01
Water-quality and biological characteristics in three streams in the Minnesota River Basin were assessed using data collected during water years 2006-08. The responses of nutrient concentrations, suspended-sediment concentrations, and biological characteristics to agricultural land retirement also were assessed. In general, total nitrogen, suspended-sediment, and chlorophyll-a concentrations, and fish resource quality improved with increasing land retirement. The Chetomba Creek, West Fork Beaver Creek, and South Branch Rush River subbasins, which range in size from about 200 to 400 square kilometers, have similar geologic and hydrologic settings but differ with respect to the amount, type, and location of retired agricultural land. Total nitrogen concentrations were largest, with a mean of 15.0 milligrams per liter (mg/L), in water samples from the South Branch Rush River, a subbasin with little to no agricultural land retirement; total nitrogen concentrations were smaller in samples from Chetomba Creek (mean of 10.6 mg/L) and West Fork Beaver Creek (mean of 7.9 mg/L), which are subbasins with more riparian or upland land retirement at the basin scale. Total phosphorus concentrations were not related directly to differing land-retirement percentages with mean concentrations at primary data-collection sites of 0.259 mg/L in the West Fork Beaver Creek subbasin, 0.164 mg/L in the Chetomba Creek subbasin, and 0.180 mg/L in the South Branch Rush River subbasin. Temporal variation in water quality was characterized using data from in-stream water-quality monitors and storm-sediment data. Fish data indicate better resource quality for the West Fork Beaver Creek subbasin than for other subbasins likely due to a combination of factors, including habitat quality, food resources, and dissolved oxygen characteristics. Index of biotic integrity (IBI) scores increased as local land-retirement percentages (within 50 and 100 meters of the streams) increased. Data and analysis from this study can be used to evaluate the success of agricultural management practices and land-retirement programs for improving stream quality.
Dong, Ling-Bo; Liu, Zhao-Gang; Li, Feng-Ri; Jiang, Li-Chun
2013-09-01
By using the branch analysis data of 955 standard branches from 60 sampled trees in 12 sampling plots of Pinus koraiensis plantation in Mengjiagang Forest Farm in Heilongjiang Province of Northeast China, and based on the linear mixed-effect model theory and methods, the models for predicting branch variables, including primary branch diameter, length, and angle, were developed. Considering tree effect, the MIXED module of SAS software was used to fit the prediction models. The results indicated that the fitting precision of the models could be improved by choosing appropriate random-effect parameters and variance-covariance structure. Then, the correlation structures including complex symmetry structure (CS), first-order autoregressive structure [AR(1)], and first-order autoregressive and moving average structure [ARMA(1,1)] were added to the optimal branch size mixed-effect model. The AR(1) improved the fitting precision of branch diameter and length mixed-effect model significantly, but all the three structures didn't improve the precision of branch angle mixed-effect model. In order to describe the heteroscedasticity during building mixed-effect model, the CF1 and CF2 functions were added to the branch mixed-effect model. CF1 function improved the fitting effect of branch angle mixed model significantly, whereas CF2 function improved the fitting effect of branch diameter and length mixed model significantly. Model validation confirmed that the mixed-effect model could improve the precision of prediction, as compare to the traditional regression model for the branch size prediction of Pinus koraiensis plantation.
Enhancing peer support for pre-registration students.
Richardson, Brian; Brown, Kate
2009-09-01
This article describes an innovation in one university in the south east of England designed to promote group identity and develop peer support among child branch nursing students. The innovation consisted of bringing all child branch students to the university twice a year to attend a study day and take part in peer-support groups. The 'Paediatric personal and professional development day' was first introduced in 2004 and was evaluated on a biannual basis over a four-year period. It was anticipated that one of the outcomes from the innovation would be to reduce attrition rates among child branch students, particularly in the common foundation programme.
METAL FORMING (INDUSTRIAL MULTIMEDIA BRANCH, SUSTAINABLE TECHNOLOGY DIVISION, NRMRL)
The Industrial Multimedia Branch's research program in metal products manufacturing was developed to identify environmental problems and deliver solutions for environmental improvements based on sustainable technology to the industry. There are over 35,000 manufacturing establish...
Imaging complex nutrient dynamics in mycelial networks.
Fricker, M D; Lee, J A; Bebber, D P; Tlalka, M; Hynes, J; Darrah, P R; Watkinson, S C; Boddy, L
2008-08-01
Transport networks are vital components of multi-cellular organisms, distributing nutrients and removing waste products. Animal cardiovascular and respiratory systems, and plant vasculature, are branching trees whose architecture is thought to determine universal scaling laws in these organisms. In contrast, the transport systems of many multi-cellular fungi do not fit into this conceptual framework, as they have evolved to explore a patchy environment in search of new resources, rather than ramify through a three-dimensional organism. These fungi grow as a foraging mycelium, formed by the branching and fusion of threadlike hyphae, that gives rise to a complex network. To function efficiently, the mycelial network must both transport nutrients between spatially separated source and sink regions and also maintain its integrity in the face of continuous attack by mycophagous insects or random damage. Here we review the development of novel imaging approaches and software tools that we have used to characterise nutrient transport and network formation in foraging mycelia over a range of spatial scales. On a millimetre scale, we have used a combination of time-lapse confocal imaging and fluorescence recovery after photobleaching to quantify the rate of diffusive transport through the unique vacuole system in individual hyphae. These data then form the basis of a simulation model to predict the impact of such diffusion-based movement on a scale of several millimetres. On a centimetre scale, we have used novel photon-counting scintillation imaging techniques to visualize radiolabel movement in small microcosms. This approach has revealed novel N-transport phenomena, including rapid, preferential N-resource allocation to C-rich sinks, induction of simultaneous bi-directional transport, abrupt switching between different pre-existing transport routes, and a strong pulsatile component to transport in some species. Analysis of the pulsatile transport component using Fourier techniques shows that as the colony forms, it self-organizes into well demarcated domains that are identifiable by differences in the phase relationship of the pulses. On the centimetre to metre scale, we have begun to use techniques borrowed from graph theory to characterize the development and dynamics of the network, and used these abstracted network models to predict the transport characteristics, resilience, and cost of the network.
Water quality of streams in the Neshaminy Creek basin, Pennsylvania
McCarren, Edward F.
1972-01-01
The Neshaminy has carved a scenic route on its way to the Delaware River, thereby helping to increase the value of land. The unabated growth of nearby metropolitan areas and the multiplying needs for water and open space for water storage and recreation in southeastern Pennsylvania have become impelling forces that mark the Neshaminy valley watershed for continued development of its land and water resources. Toward this end the Neshaminy Valley Watershed Association, Inc., which came into existence June 13, 1956, is one of several organizations dedicated to land and water-resources development in the Neshaminy Creek basin. The principal objectives of the Neshaminy Valley Watershed Association are (1) to provide for future water-supply and recreation needs, (2) to safeguard against flood and drought damage, (3) to decrease stream pollution, (4) to preserve wildlife and natural beauty, (5) to reduce soil erosion and siltation, 96) to reforest marginal land, and (7) to improve and protect existing woodland. This study shows that there is a wide variance in water quality between the West Branch and the North Branch of the Neshaminy. However, the study shows no significant difference between the chemical composition of the Little Neshaminy Creek and the main stream before they come together at Rushland. Just beyond their confluence the main stream has drained more than half its total drainage area. The average flow of the stream at this location is about 85 percent of the average flow at Langhorne. The continued presence of game fish in most of Neshaminy Creek indicates a degree of water purity that characterizes this stream as suitable for recreation. However, during the summer and early fall, several small streams feeding the Neshaminy go dry. The diminished flow during these periods and during prolonged drought impairs stream quality by causing a greater concentration of dissolved solids in water. The relatively inferior water during low-flow periods, therefore, necessitates providing more water of good quality to reservoirs for emergency releases, not only to augment supply to users in needful downstream areas but also to improve stream quality by dilution.
Hagiwara, Masaya; Peng, Fei; Ho, Chih-Ming
2015-01-27
We have succeeded in developing hollow branching structure in vitro commonly observed in lung airway using primary lung airway epithelial cells. Cell concentration gradient is the key factor that determines production of the branching cellular structures, as optimization of this component removes the need for heterotypic culture. The higher cell concentration leads to the more production of morphogens and increases the growth rate of cells. However, homogeneous high cell concentration does not make a branching structure. Branching requires sufficient space in which cells can grow from a high concentration toward a low concentration. Simulation performed using a reaction-diffusion model revealed that long-range inhibition prevents cells from branching when they are homogeneously spread in culture environments, while short-range activation from neighboring cells leads to positive feedback. Thus, a high cell concentration gradient is required to make branching structures. Spatial distributions of morphogens, such as BMP-4, play important roles in the pattern formation. This simple yet robust system provides an optimal platform for the further study and understanding of branching mechanisms in the lung airway, and will facilitate chemical and genetic studies of lung morphogenesis programs.
Development and Genetic Control of Plant Architecture and Biomass in the Panicoid Grass, Setaria
Mauro-Herrera, Margarita; Doust, Andrew N.
2016-01-01
The architecture of a plant affects its ability to compete for light and to respond to environmental stresses, thus affecting overall fitness and productivity. Two components of architecture, branching and height, were studied in 182 F7 recombinant inbred lines (RILs) at the vegetative, flowering and mature developmental stages in the panicoid C4 model grass system, Setaria. The RIL population was derived from a cross between domesticated S. italica (foxtail millet) and its wild relative S. viridis (green foxtail). In both field and greenhouse trials the wild parent was taller initially, started branching earlier, and flowered earlier, while the domesticated parent was shorter initially, but flowered later, producing a robust tall plant architecture with more nodes and leaves on the main culm and few or no branches. Biomass was highly correlated with height of the plant and number of nodes on the main culm, and generally showed a negative relationship with branch number. However, several of the RILs with the highest biomass in both trials were significantly more branched than the domesticated parent of the cross. Quantitative trait loci (QTL) analyses indicate that both height and branching are controlled by multiple genetic regions, often with QTL for both traits colocalizing in the same genomic regions. Genomic positions of several QTL colocalize with QTL in syntenic regions in other species and contain genes known to control branching and height in sorghum, maize, and switchgrass. Included in these is the ortholog of the rice SD-1 semi-dwarfing gene, which underlies one of the major Setaria height QTL. Understanding the relationships between height and branching patterns in Setaria, and their genetic control, is an important step to gaining a comprehensive knowledge of the development and genetic regulation of panicoid grass architecture. PMID:26985990
Development and Genetic Control of Plant Architecture and Biomass in the Panicoid Grass, Setaria.
Mauro-Herrera, Margarita; Doust, Andrew N
2016-01-01
The architecture of a plant affects its ability to compete for light and to respond to environmental stresses, thus affecting overall fitness and productivity. Two components of architecture, branching and height, were studied in 182 F7 recombinant inbred lines (RILs) at the vegetative, flowering and mature developmental stages in the panicoid C4 model grass system, Setaria. The RIL population was derived from a cross between domesticated S. italica (foxtail millet) and its wild relative S. viridis (green foxtail). In both field and greenhouse trials the wild parent was taller initially, started branching earlier, and flowered earlier, while the domesticated parent was shorter initially, but flowered later, producing a robust tall plant architecture with more nodes and leaves on the main culm and few or no branches. Biomass was highly correlated with height of the plant and number of nodes on the main culm, and generally showed a negative relationship with branch number. However, several of the RILs with the highest biomass in both trials were significantly more branched than the domesticated parent of the cross. Quantitative trait loci (QTL) analyses indicate that both height and branching are controlled by multiple genetic regions, often with QTL for both traits colocalizing in the same genomic regions. Genomic positions of several QTL colocalize with QTL in syntenic regions in other species and contain genes known to control branching and height in sorghum, maize, and switchgrass. Included in these is the ortholog of the rice SD-1 semi-dwarfing gene, which underlies one of the major Setaria height QTL. Understanding the relationships between height and branching patterns in Setaria, and their genetic control, is an important step to gaining a comprehensive knowledge of the development and genetic regulation of panicoid grass architecture.
The Concept of C2 Communication and Information Support
2004-06-01
communication and information literacy , • Sensors: technology and systematic development as a branch, • Military prognosis research (combat models...intelligence, • Visualization of actions, suitable forms of information presentation, • Techniques of learning CIS users communication and information ... literacy , • Sensors: technology and systematic development as a branch, • Military prognosis research (combat models), • Man - machine interface. CISu
The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis
Yates, Laura L.; Schnatwinkel, Carsten; Murdoch, Jennifer N.; Bogani, Debora; Formstone, Caroline J.; Townsend, Stuart; Greenfield, Andy; Niswander, Lee A.; Dean, Charlotte H.
2010-01-01
The lungs are generated by branching morphogenesis as a result of reciprocal signalling interactions between the epithelium and mesenchyme during development. Mutations that disrupt formation of either the correct number or shape of epithelial branches affect lung function. This, in turn, can lead to congenital abnormalities such as cystadenomatoid malformations, pulmonary hypertension or lung hypoplasia. Defects in lung architecture are also associated with adult lung disease, particularly in cases of idiopathic lung fibrosis. Identifying the signalling pathways which drive epithelial tube formation will likely shed light on both congenital and adult lung disease. Here we show that mutations in the planar cell polarity (PCP) genes Celsr1 and Vangl2 lead to disrupted lung development and defects in lung architecture. Lungs from Celsr1Crsh and Vangl2Lp mouse mutants are small and misshapen with fewer branches, and by late gestation exhibit thickened interstitial mesenchyme and defective saccular formation. We observe a recapitulation of these branching defects following inhibition of Rho kinase, an important downstream effector of the PCP signalling pathway. Moreover, epithelial integrity is disrupted, cytoskeletal remodelling perturbed and mutant endoderm does not branch normally in response to the chemoattractant FGF10. We further show that Celsr1 and Vangl2 proteins are present in restricted spatial domains within lung epithelium. Our data show that the PCP genes Celsr1 and Vangl2 are required for foetal lung development thereby revealing a novel signalling pathway critical for this process that will enhance our understanding of congenital and adult lung diseases and may in future lead to novel therapeutic strategies. PMID:20223754
Atypical chemokine receptor ACKR2 controls branching morphogenesis in the developing mammary gland
Hewit, Kay D.; Pallas, Kenneth J.; Cairney, Claire J.; Lee, Kit M.; Hansell, Christopher A.; Stein, Torsten
2017-01-01
Macrophages are important regulators of branching morphogenesis during development and postnatally in the mammary gland. Regulation of macrophage dynamics during these processes can therefore have a profound impact on development. We demonstrate here that the developing mammary gland expresses high levels of inflammatory CC-chemokines, which are essential in vivo regulators of macrophage migration. We further demonstrate that the atypical chemokine receptor ACKR2, which scavenges inflammatory CC-chemokines, is differentially expressed during mammary gland development. We have previously shown that ACKR2 regulates macrophage dynamics during lymphatic vessel development. Here, we extend these observations to reveal a novel role for ACKR2 in regulating the postnatal development of the mammary gland. Specifically, we show that Ackr2−/− mice display precocious mammary gland development. This is associated with increased macrophage recruitment to the developing gland and increased density of the ductal epithelial network. These data demonstrate that ACKR2 is an important regulator of branching morphogenesis in diverse biological contexts and provide the first evidence of a role for chemokines and their receptors in postnatal development processes. PMID:27888192
"GSFC FSB Application of Perspective-Based Inspections"
NASA Technical Reports Server (NTRS)
Shell, Elaine; Shull, Forrest
2004-01-01
The scope of work described in our proposal consisted of developing inspection standards targeted to Branch-specific types of defects (gained from analysis of Branch project defect histories), and including Branch-relevant perspectives and questions to guide defect detection. The tailored inspection guidelines were to be applied on real Branch projects with support as needed from the technology infusion team. This still accurately describes the scope of work performed. It was originally proposed that the Perspective-Based inspection standard would be applied on three projects within the Branch: GPM, JWST, and SDO. Rather than apply the proposed standard to all three, we inserted a new step, in which the standard was instead applied on a single pilot project, cFE (described above). This decision was a good match for the Branch goals since, due to the "design for reuse" nature of cFE, inspections played an even more crucial than usual role in that development process. Also, since cFE is being designed to provide general-purpose functionality, key representatives fiom our target projects were involved in inspections of cFE to provide perspectives from different missions. In this way, they could get some exposure to and the chance to provide feedback on the proposed standards before applying them on their own projects. The Branch-baselined standards will still be applied on GPM, JWST, and SDO, although outside the time frame of this funding. Finally, we originally proposed using the analysis of Branch defect sources to indicate in which phases Perspective-Based inspections could provide the best potential for future improvement, although experience on previous Branch projects suggested that our efforts would likely be focused on requirements and code inspections. In the actual work, we focused exclusively on requirements inspections, as this was the highest-priority work currently being done on our cFE pilot project.
Code of Federal Regulations, 2012 CFR
2012-04-01
..., and Social Sciences. Regulations and Special Government Employees Management Staff. Division of Social... and Management Staff. Good Clinical Practice Staff. Office of Combination Products. Office of Orphan... Branch. Division of Communication Media. Television Design and Development Branch. Division of Freedom of...
Code of Federal Regulations, 2013 CFR
2013-04-01
..., and Social Sciences. Regulations and Special Government Employees Management Staff. Division of Social... and Management Staff. Good Clinical Practice Staff. Office of Combination Products. Office of Orphan... Branch. Division of Communication Media. Television Design and Development Branch. Division of Freedom of...
Code of Federal Regulations, 2014 CFR
2014-04-01
..., and Social Sciences. Regulations and Special Government Employees Management Staff. Division of Social... and Management Staff. Good Clinical Practice Staff. Office of Combination Products. Office of Orphan... Branch. Division of Communication Media. Television Design and Development Branch. Division of Freedom of...
Electromagnetic Nucleus - Nucleus Cross Sections Using Energy Dependent Branching Ratios
NASA Astrophysics Data System (ADS)
Adamczyk, Anne; Norbury, John
2009-11-01
Energy dependent branching ratios, derived from Weisskopf-Ewing theory, are presented and compared to an energy independent formalism, developed by Norbury, Townsend, and Westfall. The energy dependent branching ratio formalism is more versatile since it allows for not only neutron and proton emission, but also alpha particle, deuteron, helion, and triton emission. A new theoretical method for calculating electromagnetic dissociation (EMD) nucleus - nucleus cross sections, with energy dependent branching ratios, is introduced. Comparisons of photonuclear and nucleus - nucleus cross sections, using energy dependent and independent branching ratios, to experiment are presented. Experimental efforts, by various groups, have focused on measuring cross sections for proton and neutron emission, because proton and neutron emission is generally more probable than heavier particle emission. Consequently, comparisons of energy dependent and independent branching ratios to experiment are made for photoneutron and photoproton cross sections. EMD cross sections for single neutron, proton, and alpha particle removal are calculated and compared to experimental data for a variety of projectile, target, and energy combinations. Results indicate that using energy dependent branching ratios yields better estimates.
The Ron Receptor Tyrosine Kinase Negatively Regulates Mammary Gland Branching Morphogenesis
Meyer, Sara E.; Zinser, Glendon M.; Stuart, William D.; Pathrose, Peterson; Waltz, Susan E.
2009-01-01
The Ron receptor tyrosine kinase is expressed in normal breast tissue and is overexpressed in approximately 50% of human breast cancers. Despite the recent studies on Ron in breast cancer, nothing is known about the importance of this protein during breast development. To investigate the functional significance of Ron in the normal mammary gland, we compared mammary gland development in wild-type mice to mice containing a targeted ablation of the tyrosine kinase (TK) signaling domain of Ron (TK−/−). Mammary glands from RonTK−/− mice exhibited accelerated pubertal development including significantly increased ductal extension and branching morphogenesis. While circulating levels of estrogen, progesterone, and overall rates of epithelial cell turnover were unchanged, significant increases in phosphorylated MAPK, which predominantly localized to the epithelium, were associated with increased branching morphogenesis. Additionally, purified RonTK−/− epithelial cells cultured ex vivo exhibited enhanced branching morphogenesis, which was reduced upon MAPK inhibition. Microarray analysis of pubertal RonTK−/− glands revealed 393 genes temporally impacted by Ron expression with significant changes observed in signaling networks regulating development, morphogenesis, differentiation, cell motility, and adhesion. In total, these studies represent the first evidence of a role for the Ron receptor tyrosine kinase as a critical negative regulator of mammary development. PMID:19576199
Software Engineering for Human Spaceflight
NASA Technical Reports Server (NTRS)
Fredrickson, Steven E.
2014-01-01
The Spacecraft Software Engineering Branch of NASA Johnson Space Center (JSC) provides world-class products, leadership, and technical expertise in software engineering, processes, technology, and systems management for human spaceflight. The branch contributes to major NASA programs (e.g. ISS, MPCV/Orion) with in-house software development and prime contractor oversight, and maintains the JSC Engineering Directorate CMMI rating for flight software development. Software engineering teams work with hardware developers, mission planners, and system operators to integrate flight vehicles, habitats, robotics, and other spacecraft elements. They seek to infuse automation and autonomy into missions, and apply new technologies to flight processor and computational architectures. This presentation will provide an overview of key software-related projects, software methodologies and tools, and technology pursuits of interest to the JSC Spacecraft Software Engineering Branch.
Evolution of the biosynthesis of the branched-chain amino acids
NASA Technical Reports Server (NTRS)
Keefe, Anthony D.; Lazcano, Antonio; Miller, Stanley L.
1995-01-01
The origins of the biosynthetic pathways for the branched-chain amino acids cannot be understood in terms of the backwards development of the present acetolactate pathway because it contains unstable intermediates. We propose that the first biosynthesis of the branched-chain amino acids was by the reductive carboxylation of short branched chain fatty acids giving keto acids which were then transaminated. Similar reaction sequences mediated by nonspecific enzymes would produce serine and threomine from the abundant prebiotic compounds glycolic and lactic acids. The aromatic amino acids may also have first been synthesized in this way, e.g. tryptophan from indole acetic acid. The next step would have been the biosynthesis of leucine from alpha-ketoisovalerc acid. The acetolactate pathway developed subsequently. The first version of the Krebs cycle, which was used for amino acid biosynthesis, would have been assembled by making use fo the reductive carboxylation and leucine biosynthesis enzymes, and completed with the development of a single new enzyme, succinate dehydrogenase. This evolutionary scheme suggests that there may be limitations to inferring the origins of metabolism by a simple back extrapolation of current pathways.
High-Resolution Inflorescence Phenotyping Using a Novel Image-Analysis Pipeline, PANorama1[W][OPEN
Crowell, Samuel; Falcão, Alexandre X.; Shah, Ankur; Wilson, Zachary; Greenberg, Anthony J.; McCouch, Susan R.
2014-01-01
Variation in inflorescence development is an important target of selection for numerous crop species, including many members of the Poaceae (grasses). In Asian rice (Oryza sativa), inflorescence (panicle) architecture is correlated with yield and grain-quality traits. However, many rice breeders continue to use composite phenotypes in selection pipelines, because measuring complex, branched panicles requires a significant investment of resources. We developed an open-source phenotyping platform, PANorama, which measures multiple architectural and branching phenotypes from images simultaneously. PANorama automatically extracts skeletons from images, allows users to subdivide axes into individual internodes, and thresholds away structures, such as awns, that normally interfere with accurate panicle phenotyping. PANorama represents an improvement in both efficiency and accuracy over existing panicle imaging platforms, and flexible implementation makes PANorama capable of measuring a range of organs from other plant species. Using high-resolution phenotypes, a mapping population of recombinant inbred lines, and a dense single-nucleotide polymorphism data set, we identify, to our knowledge, the largest number of quantitative trait loci (QTLs) for panicle traits ever reported in a single study. Several areas of the genome show pleiotropic clusters of panicle QTLs, including a region near the rice Green Revolution gene SEMIDWARF1. We also confirm that multiple panicle phenotypes are distinctly different among a small collection of diverse rice varieties. Taken together, these results suggest that clusters of small-effect QTLs may be responsible for varietal or subpopulation-specific panicle traits, representing a significant opportunity for rice breeders selecting for yield performance across different genetic backgrounds. PMID:24696519
Damage Tolerance Assessment Branch
NASA Technical Reports Server (NTRS)
Walker, James L.
2013-01-01
The Damage Tolerance Assessment Branch evaluates the ability of a structure to perform reliably throughout its service life in the presence of a defect, crack, or other form of damage. Such assessment is fundamental to the use of structural materials and requires an integral blend of materials engineering, fracture testing and analysis, and nondestructive evaluation. The vision of the Branch is to increase the safety of manned space flight by improving the fracture control and the associated nondestructive evaluation processes through development and application of standards, guidelines, advanced test and analytical methods. The Branch also strives to assist and solve non-aerospace related NDE and damage tolerance problems, providing consultation, prototyping and inspection services.
King, Wade; Ahmed, Shihab U; Baisden, Jamie; Patel, Nileshkumar; Kennedy, David J; Duszynski, Belinda; MacVicar, John
2015-02-01
To assess the evidence on the validity of sacral lateral branch blocks and the effectiveness of sacral lateral branch thermal radiofrequency neurotomy in managing sacroiliac complex pain. Systematic review with comprehensive analysis of all published data. Six reviewers searched the literature on sacral lateral branch interventions. Each assessed the methodologies of studies found and the quality of the evidence presented. The outcomes assessed were diagnostic validity and effectiveness of treatment for sacroiliac complex pain. The evidence found was appraised in accordance with the Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) system of evaluating scientific evidence. The searches yielded two primary publications on sacral lateral branch blocks and 15 studies of the effectiveness of sacral lateral branch thermal radiofrequency neurotomy. One study showed multisite, multidepth sacral lateral branch blocks can anesthetize the posterior sacroiliac ligaments. Therapeutic studies show sacral lateral branch thermal radiofrequency neurotomy can relieve sacroiliac complex pain to some extent. The evidence of the validity of these blocks and the effectiveness of this treatment were rated as moderate in accordance with the GRADE system. The literature on sacral lateral branch interventions is sparse. One study demonstrates the face validity of multisite, multidepth sacral lateral branch blocks for diagnosis of posterior sacroiliac complex pain. Some evidence of moderate quality exists on therapeutic procedures, but it is insufficient to determine the indications and effectiveness of sacral lateral branch thermal radiofrequency neurotomy, and more research is required. Wiley Periodicals, Inc.
Zhao, Daqiu; Gong, Saijie; Hao, Zhaojun; Meng, Jiasong; Tao, Jun
2015-01-01
Herbaceous peony (Paeonia lactiflora Pall.) is an emerging high-grade cut flower worldwide, which is usually used in wedding bouquets and known as the “wedding flower”. However, abundant lateral branches appear frequently in some excellent cultivars, and a lack of a method to remove Paeonia lactiflora lateral branches other than inefficient artificial methods is an obstacle for improving the quality of its cut flowers. In this study, paclobutrazol (PBZ) application was found to inhibit the growth of lateral branches in Paeonia lactiflora for the first time, including 96.82% decreased lateral bud number per branch, 77.79% and 42.31% decreased length and diameter of lateral branches, respectively, declined cell wall materials and changed microstructures. Subsequently, isobaric tag for relative and absolute quantitation (iTRAQ) technology was used for quantitative proteomics analysis of lateral branches under PBZ application and control. The results indicated that 178 differentially expressed proteins (DEPs) successfully obtained, 98 DEPs were up-regulated and 80 DEPs were down-regulated. Thereafter, 34 candidate DEPs associated with the inhibited growth of lateral branches were screened according to their function and classification. These PBZ-stress responsive candidate DEPs were involved in eight biological processes, which played a very important role in the growth and development of lateral branches together with the response to PBZ stress. These results provide a better understanding of the molecular theoretical basis for removing Paeonia lactiflora lateral branches using PBZ application. PMID:26473855
Fault Branching and Long-Term Earthquake Rupture Scenario for Strike-Slip Earthquake
NASA Astrophysics Data System (ADS)
Klinger, Y.; CHOI, J. H.; Vallage, A.
2017-12-01
Careful examination of surface rupture for large continental strike-slip earthquakes reveals that for the majority of earthquakes, at least one major branch is involved in the rupture pattern. Often, branching might be either related to the location of the epicenter or located toward the end of the rupture, and possibly related to the stopping of the rupture. In this work, we examine large continental earthquakes that show significant branches at different scales and for which ground surface rupture has been mapped in great details. In each case, rupture conditions are described, including dynamic parameters, past earthquakes history, and regional stress orientation, to see if the dynamic stress field would a priori favor branching. In one case we show that rupture propagation and branching are directly impacted by preexisting geological structures. These structures serve as pathways for the rupture attempting to propagate out of its shear plane. At larger scale, we show that in some cases, rupturing a branch might be systematic, hampering possibilities for the development of a larger seismic rupture. Long-term geomorphology hints at the existence of a strong asperity in the zone where the rupture branched off the main fault. There, no evidence of throughgoing rupture could be seen along the main fault, while the branch is well connected to the main fault. This set of observations suggests that for specific configurations, some rupture scenarios involving systematic branching are more likely than others.
,
1909-01-01
This volume contains results of flow measurements made on certain streams in the United States. The work was performed by the water-resources branch of the United States Geological Survey, either independently or in cooperation with organizations mentioned herein. These investigations are authorized by the organic law of the Geological Survey (Stat. L., vol. 20, p. 394)...
2013-06-13
The survey was reviewed and approved by the CGSC Human Protections Administrator under the number #13-03-055. This survey targeted an audience of ...merging the human resources from both organizations for “high reward low cost” operations. At the operational level, an overall review of the ...indirect approaches, in order to successfully take up the conflict prevention challenge. Assessing the robustness of an
The Power to Declare War: The Ultimate Check on Presidential Power
2012-03-07
action through a resolution or by continued funding. When Congress does declare war it grants sweeping powers to the Executive Branch that threatens...formally declare war. If war only requires limited resources then Congress authorizes the action through a resolution or by continued funding. When...surface it may appear that Congress has not performed its constitutional obligations by authorizing military actions without issuing a formal
2014-04-01
FISCAM Federal Information System Controls Audit Manual FMFIA Federal Managers’ Financial Integrity Act FMR Financial Management Regulation GAAP ...rules are incorporated into generally accepted accounting principles ( GAAP ) for the federal government. For additional information on the two methods of...to hold executive branch officials accountable for proper use of budgetary resources, and to ensure proper stewardship and transparency of the use
ERIC Educational Resources Information Center
Eddow, Christine
2017-01-01
Physical therapy is a branch of healthcare that has advanced from an ancillary support role to an autonomous doctoral level profession in only two decades. Enrollment in physical therapy programs is increasing while resources and program length remain limited, leaving academic leaders challenged to identify instructional methods to manage…
Rodney E. Will; Nikhil Narahari; Robert O. Teskey; Barry D. Shiver; Matthew Wosotowsky
2006-01-01
Increased planting density enhances overall stand growth by increasing resource capture and use. However, planting density also may affect the proportion of biomass partitioned to stem growth, a main factor controlling stand growth and yield. During the fourth growing season, we determined the biomass partitioned to leaf, branch, stem, and fine root (> 0.5mm) of...
Area Handbook Series: Lebanon: A Country Study
1989-01-01
government surveys most Lebanese were adequately sheltered and fed. Known for their ingenuity and resourcefulness in trading and in entrepreneurship ...proceedings in 1985. In 1985 Bank Al Mashrek also bough’ two branches of the Brit- ish Standard Chartered Bank. Banque Libano- Franchise bought the...closed their Beirut operations, the former handing over its business to Banque Sabbag et Franchise pour le Moyen Orient. By the end of 1986, only
SERM Forest Fire Chronology of Saskatchewan in Vector Format
NASA Technical Reports Server (NTRS)
Naelapea, Ott; Nickeson, Jaime; Hall, Forrest G. (Editor)
2000-01-01
The BOReal Ecosystem-Atmosphere Study (BOREAS) staff personnel worked with several Canadian agencies to obtain various GIS data for use in the research efforts. This data set is a series of ARC/INFO export files of the fire history of Saskatchewan by year from 1945 to 1996, with a few missing years. The data set was compiled and provided by the Saskatchewan Environment and Resource Management (SERM) Wildlife Branch.
PUBLICATIONS - AIR POLLUTION PREVENTION AND CONTROL TECHNOLOGY
The Air Pollution Prevention and Control Division (APPCD)publishes highly scientific and technical information developed through its four research branches. A list of key publications produced by the individual branches can be viewed by visiting the website for the respective bra...
Atomic Oscillator Strengths in the Vacuum Ultraviolet
NASA Technical Reports Server (NTRS)
Nave, Gillian; Sansonetti, Craig J.; Szabo, Csilla I.
2006-01-01
We have developed techniques to measure branching fractions in the vacuum ultraviolet using diffraction grating spectroscopy and phosphor image plates as detectors. These techniques have been used to measure branching fractions in Fe II that give prominent emission lines in astrophysical objects.
Torres‐Ruiz, José M.; Poyatos, Rafael; Martinez‐Vilalta, Jordi; Meir, Patrick; Cochard, Hervé; Mencuccini, Maurizio
2015-01-01
Abstract Understanding physiological processes involved in drought‐induced mortality is important for predicting the future of forests and for modelling the carbon and water cycles. Recent research has highlighted the variable risks of carbon starvation and hydraulic failure in drought‐exposed trees. However, little is known about the specific responses of leaves and supporting twigs, despite their critical role in balancing carbon acquisition and water loss. Comparing healthy (non‐defoliated) and unhealthy (defoliated) Scots pine at the same site, we measured the physiological variables involved in regulating carbon and water resources. Defoliated trees showed different responses to summer drought compared with non‐defoliated trees. Defoliated trees maintained gas exchange while non‐defoliated trees reduced photosynthesis and transpiration during the drought period. At the branch scale, very few differences were observed in non‐structural carbohydrate concentrations between health classes. However, defoliated trees tended to have lower water potentials and smaller hydraulic safety margins. While non‐defoliated trees showed a typical response to drought for an isohydric species, the physiology appears to be driven in defoliated trees by the need to maintain carbon resources in twigs. These responses put defoliated trees at higher risk of branch hydraulic failure and help explain the interaction between carbon starvation and hydraulic failure in dying trees. PMID:25997464
NASA Astrophysics Data System (ADS)
Berezin, Alexander A.
2003-04-01
Why there is Something rather than Nothing? From Pythagoras ("everything is number") to Wheeler ("it from bit") theme of ultimate origin stresses primordiality of Ideal Platonic World (IPW) of mathematics. Even popular "quantum tunnelling out of nothing" can specify "nothing" only as (essentially) IPW. IPW exists everywhere (but nowhere in particular) and logically precedes space, time, matter or any "physics" in any conceivable universe. This leads to propositional conjecture (axiom?) that (meta)physical "Platonic Pressure" of infinitude of numbers acts as engine for self-generation of physical universe directly out of mathematics: cosmogenesis is driven by the very fact of IPW inexhaustibility. While physics in other quantum branches of inflating universe (Megaverse)can be(arbitrary) different from ours, number theory (and rest of IPW)is not (it is unique, absolute, immutable and infinitely resourceful). Let (infinite) totality of microstates ("its") of entire Megaverse form countable set. Since countable sets are hierarchically inexhaustible (Cantor's "fractal branching"), each single "it" still has infinite tail of non-overlapping IPW-based "personal labels". Thus, each "bit" ("it") is infinitely and uniquely resourceful: possible venue of elimination ergodicity basis for eternal return cosmological argument. Physics (in any subuniverse) may be limited only by inherent impossibilities residing in IPW, e.g. insolvability of Continuum Problem may be IPW foundation of quantum indeterminicity.
1986-02-01
RESEARCH NOTE 86-23 DEVELOPMENT OF A SINGLE LIST OF LEADERSHIP / MANAGEMENT NON-MOS OR BRANCH SPECIFIC TASKS FOR OFFICERS AND NONCOMMISSIONED OFFICERS...Noncommissioned Officers ........................ B-i APPENDIX C: Single List of Leadership / Management Tasks For Officers and Noncommissioned Officers Organized...task ita bank. 7 CONCLUS IONS A single leadership / management task list for officers and NCOs is a logical step in developing a taxonomy of tasks
Extracellular matrix and growth factors in branching morphogenesis
NASA Technical Reports Server (NTRS)
Hardman, P.; Spooner, B. S.
1993-01-01
The unifying hypothesis of the NSCORT in gravitational biology postulates that the ECM and growth factors are key interrelated components of a macromolecular regulatory system. The ECM is known to be important in growth and branching morphogenesis of embryonic organs. Growth factors have been detected in the developing embryo, and often the pattern of localization is associated with areas undergoing epithelial-mesenchymal interactions. Causal relationships between these components may be of fundamental importance in control of branching morphogenesis.
Research highlights of the global modeling and simulation branch for 1986-1987
NASA Technical Reports Server (NTRS)
Baker, Wayman (Editor); Susskind, Joel (Editor); Pfaendtner, James (Editor); Randall, David (Editor); Atlas, Robert (Editor)
1988-01-01
This document provides a summary of the research conducted in the Global Modeling and Simulation Branch and highlights the most significant accomplishments in 1986 to 1987. The Branch has been the focal point for global weather and climate prediction research in the Laboratory for Atmospheres through the retrieval and use of satellite data, the development of global models and data assimilation techniques, the simulation of future observing systems, and the performance of atmospheric diagnostic studies.
SDF1 Reduces Interneuron Leading Process Branching through Dual Regulation of Actin and Microtubules
Lysko, Daniel E.; Putt, Mary
2014-01-01
Normal cerebral cortical function requires a highly ordered balance between projection neurons and interneurons. During development these two neuronal populations migrate from distinct progenitor zones to form the cerebral cortex, with interneurons originating in the more distant ganglionic eminences. Moreover, deficits in interneurons have been linked to a variety of neurodevelopmental disorders underscoring the importance of understanding interneuron development and function. We, and others, have identified SDF1 signaling as one important modulator of interneuron migration speed and leading process branching behavior in mice, although how SDF1 signaling impacts these behaviors remains unknown. We previously found SDF1 inhibited leading process branching while increasing the rate of migration. We have now mechanistically linked SDF1 modulation of leading process branching behavior to a dual regulation of both actin and microtubule organization. We find SDF1 consolidates actin at the leading process tip by de-repressing calpain protease and increasing proteolysis of branched-actin-supporting cortactin. Additionally, SDF1 stabilizes the microtubule array in the leading process through activation of the microtubule-associated protein doublecortin (DCX). DCX stabilizes the microtubule array by bundling microtubules within the leading process, reducing branching. These data provide mechanistic insight into the regulation of interneuron leading process dynamics during neuronal migration in mice and provides insight into how cortactin and DCX, a known human neuronal migration disorder gene, participate in this process. PMID:24695713
Integrative Physical and Cognitive Training Development to Better Meet Airman Mission Requirements
2015-07-26
Warfighter Interface Division Applied Neuroscience Branch Wright-Patterson AFB OH 45433 711 HPW/RHCP 11. SPONSOR/MONITOR’S REPORT NUMBER(S...Interface Division) and Erica Johnson (AFRL, Applied Neuroscience Branch) for their contributions in technical development and manuscript editing that...Liston C. Hobson J. Stickgold, R. Cognitive flexibility across the sleep–wake cycle: REM-sleep enhancement of anagram problem solving. Cogn Brain
Propagation-Loss Measurements and Modelling for Topographically Smooth and Rough Seabeds
1989-06-01
34 - UNLIMITED DISTRIBUTION I * National Defence Defense nationale Research and -urcau de recherche Development Branch et developpoment TECHNICAL...Desharnais DTI SEP 1419899 Defence - - Centre de Research 4 Recherches pour la Establishment Defense Atlantic Atlantique Canada8 89 9 14 018 r5Tn f" S...Defence Defense nationale Research and Bureau de recherche Development Branch et developpement PROPAGATION-LOSS MEASUREMENTS AND MODELLING FOR
NASA Technical Reports Server (NTRS)
Desautel, Richard
1993-01-01
The objectives of this research include supporting the Aerothermodynamics Branch's research by developing graphical visualization tools for both the branch's adaptive grid code and flow field ray tracing code. The completed research for the reporting period includes development of a graphical user interface (GUI) and its implementation into the NAS Flowfield Analysis Software Tool kit (FAST), for both the adaptive grid code (SAGE) and the flow field ray tracing code (CISS).
Morphodynamics of growing bacterial colony
NASA Astrophysics Data System (ADS)
Ghosh, Pushpita; Perlekar, Prasad; Rana, Navdeep
Self-organization into multicellular communities is a natural trend of most of the bacteria. Mutual interactions and competition among the bacterial cells in such multicellular organization play essential role in governing the spatiotemporal dynamics. We here present the spatiotemporal dynamics of growing bacterial colony using theory and a particle-based or individual-based simulation model of nonmotile cells growing utilizing a diffusing nutrient/food on a semi-solid surface by their growth and division forces and by pushing each-other through sliding motility. We show how the resource competition over a fixed amount of food, the diffusion coefficient of the nutrient and the random genetic noise govern the morphodynamics of a single species and a well-mixed two-species bacterial colonies. Our results show that for a very low initial food concentrations, colony develops fingering pattern at the front, while for intermediate values of initial food sources, the colony undergoes transitions to branched structures at the periphery and for very high values of food colony develops smoother fronts.
Thermoelectric effects in disordered branched nanowires
NASA Astrophysics Data System (ADS)
Roslyak, Oleksiy; Piriatinskiy, Andrei
2013-03-01
We shall develop formalism of thermal and electrical transport in Si1 - x Gex and BiTe nanowires. The key feature of those nanowires is the possibility of dendrimer type branching. The branching tree can be of size comparable to the short wavelength of phonons and by far smaller than the long wavelength of conducting electrons. Hence it is expected that the branching may suppress thermal and let alone electrical conductance. We demonstrate that the morphology of branches strongly affects the electronic conductance. The effect is important to the class of materials known as thermoelectrics. The small size of the branching region makes large temperature and electrical gradients. On the other hand the smallness of the region would allow the electrical transport being ballistic. As usual for the mesoscopic systems we have to solve macroscopic (temperature) and microscopic ((electric potential, current)) equations self-consistently. Electronic conductance is studied via NEGF formalism on the irreducible electron transfer graph. We also investigate the figure of merit ZT as a measure of the suppressed electron conductance.
NASA Technical Reports Server (NTRS)
Smith, Thomas
2015-01-01
The duration of my Summer 2015 Internship Tour at NASA's Johnson Space Center was spent working in the Structural Engineering Division's Structures Branch. One of the two main roles of the Structures Branch, ES2, is to ensure the structural integrity of spacecraft vehicles and the structural subsystems needed to support those vehicles. The other main objective of this branch is to develop the lightweight structures that are necessary to take humans beyond Low-Earth Orbit. Within ES2, my four projects involved inflatable space structure air bladder material testing; thermal and impact material testing for spacecraft windows; structural analysis on a joint used in the Boeing CST-100 airbag system; and an additive manufacturing design project.
Straub, Timothy D.; Johnson, Gary P.; Roseboom, Donald P.; Sierra, Carlos R.
2006-01-01
Judy's Branch watershed, a small basin (8.64 square miles) in the St. Louis Metro East region in Illinois, was selected as a pilot site to determine suspended-sediment yields and stream-channel processes in the bluffs and American Bottoms (expansive low-lying valley floor in the region). Suspended-sediment and stream-chan-nel data collected and analyzed for Judy's Branch watershed are presented in this report to establish a baseline of data for water-resource managers to evaluate future stream rehabilitation and manage-ment alternatives. The sediment yield analysis determines the amount of sediment being delivered from the watershed and two subwatersheds: an urban tributary and an undeveloped headwater (pri-marily agricultural). The analysis of the subwater-sheds is used to compare the effects of urbanization on sediment yield to the river. The stream-channel contribution to sediment yield was determined by evaluation of the stream-channel processes operat-ing on the streambed and banks of Judy's Branch watershed. Bank stability was related to hydrologic events, bank stratigraphy, and channel geometry through model development and simulation. The average suspended-sediment yield from two upland subwatersheds (drainage areas of 0.23 and 0.40 sq.mi. was 1,163 tons per square mile per year (tons/sq.mi.-year) between July 2000 and June 2004. The suspended-sediment yield at the Route 157 station was 2,523 tons/sq.mi.-year, near the outlet of Judy's Branch watershed (drainage area = 8.33 sq.mi.). This is approximately 1,360 tons/sq.mi.-year greater than the average at the upland stations for the same time period. This result is unexpected in that, generally, the suspended-sediment yield decreases as the watershed area increases because of sediment stored in the channel and flood plain. The difference indicates a possible increase in yield from a source, such as bank retreat, and supports the concept that land-use changes increase stream-flows that may in turn result in higher rates of bank retreat. Utilizing both bank-rod data and resurveyed cross-section data, it was determined that approxi-mately half of the suspended- sediment yield at Route 157 during July 2000-June 2004 came from bank retreat. Given that bank retreat can be a substantial portion of the sediment yield, understanding bank stability processes is important. Bank stability can be assessed mathematically by computing the factor of safety, which is defined by the ratio of the shear strength (resisting force) along the failure surface and the shear stress (driving gravitational force). Once the factor of safety falls below one, the bank theoretically becomes unstable. Bank-stability conditions were related to hydrologic events, bank type, and channel geometry through model develop-ment and simulation. The most common type of bank in the watershed consists of cohesive alluvial soil deposits overlying a stiff glacial till. A stabil-ity chart for different bank types was developed using a bank-stability analysis. Banks steeper than 70 degrees and higher than from 10 to 11.5 feet (depending on bank type) become at risk for mass failure in the watershed under conditions that pro-mote saturation of the bank and a sudden drop in the river level.
Escos, J.; Alados, C.L.; Pugnaire, F. I.; Puigdefábregas, J.; Emlen, J.
2000-01-01
This paper investigates allocation of energy to mechanisms that generate and preserve architectural forms (i.e. developmental stability, complexity of branching patterns) and productivity (growth and reproduction) in response to environmental disturbances (i.e. grazing and resource availability). The statistical error in translational symmetry was used to detect random intra-individual variability during development. This can be thought of as a measure of developmental instability caused by stress. Additionally, we use changes in fractal complexity and shoot distribution of branch structures as an alternate indicator of stress. These methods were applied to Anthyllis cytisoides L., a semi-arid environment shrub, to ascertain the effect of grazing and slope exposure on developmental traits in a 2×2 factorial design. The results show that A. cytisoidesmaintains developmental stability at the expense of productivity. Anthyllis cytisoides was developmentally more stable when grazed and when on south-facing, as opposed to north-facing slopes. On the contrary, shoot length, leaf area, fractal dimension and reproductive-to-vegetative allocation ratio were larger in north- than in south-facing slopes. As a consequence, under extreme xeric conditions, shrub mortality increased in north-facing slopes, especially when not grazed. The removal of transpiring area and the reduction of plant competition favoured developmental stability and survival in grazed plants. Differences between grazed and ungrazed plants were most evident in more mesic (north-facing) areas.
Clinton administration forging population-foreign policy links.
De Sherbinin, A
1994-12-01
In the US, the Clinton administration has renewed the link between global population and national security issues. These so-called "soft security issues" receive attention from the Under-Secretary of State for Global Affairs, Tim Wirth, and the senior director of the Global Environmental Affairs branch of the National Security Council, Eileen Claussen. Wirth and Claussen draft the US response to soft security issues such as environmental security, refugee and migration movements, political instability, and religious and ethnic conflict as well as the other nonmilitary threats of illegal drug trafficking, terrorism, and international organized crime. Population was first considered a foreign policy concern in the 1960s. By 1965, President Johnson decided that the US would provide family planning supplies and technical assistance to any country which asked for help. The initial justification for assuming a leading role in developing innovative population strategies for less developed countries was a humanitarian desire to forward economic development, the self-interest of maintaining access to resources, and concern that rapid growth produced more communists. Today the US remains concerned about resource access and economic development and is also wary of spill-over environmental effects, economic migration, diminished US trade opportunities, political asylum seekers and refugees, and increasing demand for US peacekeepers. It is also believed that rapid population growth leads to political destabilization. Critics of these views blame the development difficulties of less developed countries on poor governing decisions (inadequate institutions, trade barriers, or indifference). Women's reproductive rights advocates fear that using security as a rationale for population assistance could lead to restrictions on women's rights to choose the number and spacing of births. Despite such objections, the belief that population growth is an underlying problem in imploding states like Haiti, Rwanda, and Somalia has turned the attention of US policy-makers to these soft security issues.
Radioiodinated branched carbohydrates
Goodman, Mark M.; Knapp, Jr., Furn F.
1989-01-01
A radioiodinated branched carbohydrate for tissue imaging. Iodine-123 is stabilized in the compound by attaching it to a vinyl functional group that is on the carbohydrate. The compound exhibits good uptake and retention and is promising in the development of radiopharmaceuticals for brain, heart and tumor imaging.
Joint evolution of specialization and dispersal in structured metapopulations.
Nurmi, Tuomas; Parvinen, Kalle
2011-04-21
We study the joint evolution of dispersal and specialization concerning resource usage in a mechanistically underpinned structured discrete-time metapopulation model. We show that dispersal significantly affects the evolution of specialization and that specialization is a key factor that determines the possibility of evolutionary branching in dispersal propensity. Allowing both dispersal propensity and specialization to evolve as a consequence of natural selection is necessary in order to understand the evolutionary dynamics. The joint evolution of dispersal and specialization forms a natural evolutionary path leading to the coexistence of generalists and specialists. We show that in this process, the number of different patch types and the resource distribution are essential. Copyright © 2011 Elsevier Ltd. All rights reserved.
Spaceport Processing System Development Lab
NASA Technical Reports Server (NTRS)
Dorsey, Michael
2013-01-01
The Spaceport Processing System Development Lab (SPSDL), developed and maintained by the Systems Hardware and Engineering Branch (NE-C4), is a development lab with its own private/restricted networks. A private/restricted network is a network with restricted or no communication with other networks. This allows users from different groups to work on their own projects in their own configured environment without interfering with others utilizing their resources in the lab. The different networks being used in the lab have no way to talk with each other due to the way they are configured, so how a user configures his software, operating system, or the equipment doesn't interfere or carry over on any of the other networks in the lab. The SPSDL is available for any project in KSC that is in need of a lab environment. My job in the SPSDL was to assist in maintaining the lab to make sure it's accessible for users. This includes, but is not limited to, making sure the computers in the lab are properly running and patched with updated hardware/software. In addition to this, I also was to assist users who had issues in utilizing the resources in the lab, which may include helping to configure a restricted network for their own environment. All of this was to ensure workers were able to use the SPSDL to work on their projects without difficulty which would in turn, benefit the work done throughout KSC. When I wasn't working in the SPSDL, I would instead help other coworkers with smaller tasks which included, but wasn't limited to, the proper disposal, moving of, or search for essential equipment. I also, during the free time I had, used NASA's resources to increase my knowledge and skills in a variety of subjects related to my major as a computer engineer, particularly in UNIX, Networking, and Embedded Systems.
[Branches of the National Institute of Hygiene].
Gromulska, Marta
2008-01-01
National Epidemiological Institute (National Institute of Hygiene, from 7th September 1923) was established in 1918 in Warsaw and acted at national level. Its actions in the field of diseases combat were supported by bacteriological stations and vaccine production in voivodeship cities, which were taken charge of by the state, and names "National Epidemiological Institutes". According to the ministers resolution from 6th July 1921,Epidemiological Institutes were merged to National Central Epidemiological Institutes (PZH), the epidemiological institutes outside Warsaw were named branches, which were to be located in every voivodeship city, according to the initial organizational resolutions. There were country branches of NCEI in: Cracow, Lwów, Lódź, Toruń, Lublin, and Wilno in the period 1919-1923. New branches in Poznań (1925), Gdynia(1934), Katowice (Voivodeship Institute of Hygiene (1936), Luck (1937), Stanisławów (1937), Kielce(1938), and Brześć/Bug (Municipal Station acting as branch of National Central Epidemiological Institute. Branches were subordinated to NCEI-PZH) in Warsaw where action plans and unified research and diagnostic method were established and annual meeting of the country branches managers took place. All branches cooperated with hospitals, national health services, district general practitioners and administration structure in control of infectious diseases. In 1938, the post of branch inspector was established, the first of whom was Feliks Przesmycki PhD. Branches cooperated also with University of Cracow, University of Lwów and University of Wilno. In 1935, National Institutes of Food Research was incorporated in PZH, Water Department was established, and these areas of activity began to develop in the branches accordingly. In 1938 there were 13 branches of PZH, and each had three divisions: bacteriological, food research and water research. Three branches in Cracow, Kielce and Lublin worked during World War II under German supervision. PZH activities were restored in 1945 with new branches in Gdańsk, Wrocław(1945), Olsztyn and Szczecin (1947), and Rzeszów (1950). In 1951 there were already 14 country branches of National Institute of Hygiene (PZH) in voivodeship cities and 4 minor branches in Zakopane, Radom, Czestochowa and Walbrzych. In 31th December branches of the National Institute of Hygiene (PZH) were restructured and named Sanitary-Epidemiological Stations.
Usui, Noriyoshi; Watanabe, Keisuke; Ono, Katsuhiko; Tomita, Koichi; Tamamaki, Nobuaki; Ikenaka, Kazuhiro; Takebayashi, Hirohide
2012-03-01
Sensory neurons possess the central and peripheral branches and they form unique spinal neural circuits with motoneurons during development. Peripheral branches of sensory axons fasciculate with the motor axons that extend toward the peripheral muscles from the central nervous system (CNS), whereas the central branches of proprioceptive sensory neurons directly innervate motoneurons. Although anatomically well documented, the molecular mechanism underlying sensory-motor interaction during neural circuit formation is not fully understood. To investigate the role of motoneuron on sensory neuron development, we analyzed sensory neuron phenotypes in the dorsal root ganglia (DRG) of Olig2 knockout (KO) mouse embryos, which lack motoneurons. We found an increased number of apoptotic cells in the DRG of Olig2 KO embryos at embryonic day (E) 10.5. Furthermore, abnormal axonal projections of sensory neurons were observed in both the peripheral branches at E10.5 and central branches at E15.5. To understand the motoneuron-derived factor that regulates sensory neuron development, we focused on neurotrophin 3 (Ntf3; NT-3), because Ntf3 and its receptors (Trk) are strongly expressed in motoneurons and sensory neurons, respectively. The significance of motoneuron-derived Ntf3 was analyzed using Ntf3 conditional knockout (cKO) embryos, in which we observed increased apoptosis and abnormal projection of the central branch innervating motoneuron, the phenotypes being apparently comparable with that of Olig2 KO embryos. Taken together, we show that the motoneuron is a functional source of Ntf3 and motoneuron-derived Ntf3 is an essential pre-target neurotrophin for survival and axonal projection of sensory neurons.
Myers, C M; Whitington, P M; Ball, E E
1990-01-01
Intracellular dye fills have been used to reveal the pattern of embryonic growth of each of the four neurons which innervate the extensor tibiae muscle (ETi) of the hind leg of the locust. The growth cone of the slow extensor tibiae motoneuron (SETi), the first of the four neurons to leave the central nervous system, pioneers nerve 3 (N3). The fast extensor motoneuron (FETi), the next neuron to grow out, follows earlier outgrowing motoneurons into the periphery in nerve 5 (N5) and then rejoins SETi in N3. As it transfers from N5 to N3, it is transiently dye-coupled to the Tr1 pioneer neuron which spans the gap between the two nerves. It then follows SETi onto the ETi muscle in the femur. The common inhibitory neuron and the dorsal unpaired median neuron (DUMETi) follow SETi and FETi in nerves 3B2 and 5B1, respectively. SETi's growth cone requires almost twice as long to reach ETi as those of the three later motoneurons, all of which follow preexisting neural pathways. At least three of the four developing motoneurons form one or more axon branches not found in the adult. These branches may occur (1) at segmental boundaries; (2) where the nerve, which the growth cone is following, itself branches or the growth cone encounters another nerve; or (3) when the axon continues to grow beyond its target muscle. These findings contrast with the apparent absence of inappropriate axon branches in another developing locust neuromuscular system and during the innervation of zebrafish myotomes, but resemble in some ways the transient production of inappropriate axonal branches reported for embryonic leech motoneurons.
NASA Glenn Research Center Electrochemistry Branch Overview
NASA Technical Reports Server (NTRS)
Manzo, Michelle A.; Hoberecht, Mark; Reid, Concha
2010-01-01
This presentation covers an overview of NASA Glenn's history and heritage in the development of electrochemical systems for aerospace applications. Current programs related to batteries and fuel cells are addressed. Specific areas of focus are Li-ion batteries and Polymer Electrolyte Membrane Fuel cells systems and their development for future Exploration missions. The presentation covers details of current component development efforts for high energy and ultra high energy Li-ion batteries and non-flow-through fuel cell stack and balance of plant development. Electrochemistry Branch capabilities and facilities are also addressed.
Parental child murder and child abuse in Anglo-American legal system.
Gurevich, Liena
2010-01-01
In this article, the sociological and historical approaches and literatures are synthesized to present the historical background of the treatment that child-abusing and child-killing parents are receiving in the legal system today. The roots of the formation of contemporary institutional responses to severe child abuse and child homicide are traced and latest developments are examined critically. Durkheim's insights regarding the functions of law are highlighted by pointing out how, throughout history, crimes against children become stand-ins for larger societal problem. The latest innovations in the criminal branch of child protection consist of the specialized prosecution bureaus and court parts dealing with physical and sexual violence against children. Integral to the new developments in child protection are ''multidisciplinary,'' comprehensive approaches to the processing of criminal cases, involving teams consisting of representatives from the police, the prosecution, public and private social work and child protection agencies, and psychiatric, pediatric, and other medical practitioners and community partners. These developments exemplify heightened focus on criminal prosecution of parental crimes against children, inevitably leading to questions and policy concerns regarding resources geared toward punishment rather than prevention.
NASA Astrophysics Data System (ADS)
Sankatsing Nava, Tibisay; Russo, Pedro
2015-08-01
Universe Awareness (UNAWE) is an educational programme coordinated by Leiden University that uses the beauty and grandeur of the Universe to encourage young children, particularly those from an underprivileged background, to have an interest in science and technology and foster their sense of global citizenship from the earliest age.UNAWE's twofold vision uses our Universe to inspire and motivate very young children: the excitement of the Universe provides an exciting introduction to science and technology, while the vastness and beauty of the Universe helps broaden the mind and stimulate a sense of global citizenship and tolerance. UNAWE's goals are accomplished through four main activities: the coordination of a global network of more than 1000 astronomers, teachers and educators from more than 60 countries, development of educational resources, teacher training activities and evaluation of educational activities.Between 2011 and 2013, EU-UNAWE, the European branch of UNAWE, was funded by the European Commission to implement a project in 5 EU countries and South Africa. This project has been concluded successfully. Since then, the global project Universe Awareness has continued to grow with an expanding international network, new educational resources and teacher trainings and a planned International Workshop in collaboration with ESA in October 2015, among other activities.
Water-Based Coating Simplifies Circuit Board Manufacturing
NASA Technical Reports Server (NTRS)
2008-01-01
The Structures and Materials Division at Glenn Research Center is devoted to developing advanced, high-temperature materials and processes for future aerospace propulsion and power generation systems. The Polymers Branch falls under this division, and it is involved in the development of high-performance materials, including polymers for high-temperature polymer matrix composites; nanocomposites for both high- and low-temperature applications; durable aerogels; purification and functionalization of carbon nanotubes and their use in composites; computational modeling of materials and biological systems and processes; and developing polymer-derived molecular sensors. Essentially, this branch creates high-performance materials to reduce the weight and boost performance of components for space missions and aircraft engine components. Under the leadership of chemical engineer, Dr. Michael Meador, the Polymers Branch boasts world-class laboratories, composite manufacturing facilities, testing stations, and some of the best scientists in the field.
Yamada, Aya; Futagi, Masaharu; Fukumoto, Emiko; Saito, Kan; Yoshizaki, Keigo; Ishikawa, Masaki; Arakaki, Makiko; Hino, Ryoko; Sugawara, Yu; Ishikawa, Momoko; Naruse, Masahiro; Miyazaki, Kanako; Nakamura, Takashi; Fukumoto, Satoshi
2016-01-08
Cell-cell interaction via the gap junction regulates cell growth and differentiation, leading to formation of organs of appropriate size and quality. To determine the role of connexin43 in salivary gland development, we analyzed its expression in developing submandibular glands (SMGs). Connexin43 (Cx43) was found to be expressed in salivary gland epithelium. In ex vivo organ cultures of SMGs, addition of the gap junctional inhibitors 18α-glycyrrhetinic acid (18α-GA) and oleamide inhibited SMG branching morphogenesis, suggesting that gap junctional communication contributes to salivary gland development. In Cx43(-/-) salivary glands, submandibular and sublingual gland size was reduced as compared with those from heterozygotes. The expression of Pdgfa, Pdgfb, Fgf7, and Fgf10, which induced branching of SMGs in Cx43(-/-) samples, were not changed as compared with those from heterozygotes. Furthermore, the blocking peptide for the hemichannel and gap junction channel showed inhibition of terminal bud branching. FGF10 induced branching morphogenesis, while it did not rescue the Cx43(-/-) phenotype, thus Cx43 may regulate FGF10 signaling during salivary gland development. FGF10 is expressed in salivary gland mesenchyme and regulates epithelial proliferation, and was shown to induce ERK1/2 phosphorylation in salivary epithelial cells, while ERK1/2 phosphorylation in HSY cells was dramatically inhibited by 18α-GA, a Cx43 peptide or siRNA. On the other hand, PDGF-AA and PDGF-BB separately induced ERK1/2 phosphorylation in primary cultured salivary mesenchymal cells regardless of the presence of 18α-GA. Together, our results suggest that Cx43 regulates FGF10-induced ERK1/2 phosphorylation in salivary epithelium but not in mesenchyme during the process of SMG branching morphogenesis. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.
National Centers for Environmental Prediction
Organization Search Enter text Search Navigation Bar End Cap Search EMC Go Branches Global Climate and Weather / VISION | About EMC EMC > GLOBAL BRANCH > GFS > HOME Home Implementations Documentation References Products Model Guidance Performance Developers VLab GLOBAL FORECAST SYSTEM Global Data
Epicormic branching on pruned white fir
Richard D. Cosens
1952-01-01
Epicormic branches have developed on white fir (Abies concolor) one to two years after part of the live limbs were removed in a pruning experiment. The appearance of an average of six epicormic sprouts per tree raises some doubt as to the desirability of planting this species.
Rosário, Marta; Schuster, Steffen; Jüttner, René; Parthasarathy, Srinivas; Tarabykin, Victor; Birchmeier, Walter
2012-08-01
Neocortical neurons have highly branched dendritic trees that are essential for their function. Indeed, defects in dendritic arborization are associated with human neurodevelopmental disorders. The molecular mechanisms regulating dendritic arbor complexity, however, are still poorly understood. Here, we uncover the molecular basis for the regulation of dendritic branching during cortical development. We show that during development, dendritic branching requires post-mitotic suppression of the RhoGTPase Cdc42. By generating genetically modified mice, we demonstrate that this is catalyzed in vivo by the novel Cdc42-GAP NOMA-GAP. Loss of NOMA-GAP leads to decreased neocortical volume, associated specifically with profound oversimplification of cortical dendritic arborization and hyperactivation of Cdc42. Remarkably, dendritic complexity and cortical thickness can be partially restored by genetic reduction of post-mitotic Cdc42 levels. Furthermore, we identify the actin regulator cofilin as a key regulator of dendritic complexity in vivo. Cofilin activation during late cortical development depends on NOMA-GAP expression and subsequent inhibition of Cdc42. Strikingly, in utero expression of active cofilin is sufficient to restore postnatal dendritic complexity in NOMA-GAP-deficient animals. Our findings define a novel cell-intrinsic mechanism to regulate dendritic branching and thus neuronal complexity in the cerebral cortex.
A role for the root cap in root branching revealed by the non-auxin probe naxillin.
De Rybel, Bert; Audenaert, Dominique; Xuan, Wei; Overvoorde, Paul; Strader, Lucia C; Kepinski, Stefan; Hoye, Rebecca; Brisbois, Ronald; Parizot, Boris; Vanneste, Steffen; Liu, Xing; Gilday, Alison; Graham, Ian A; Nguyen, Long; Jansen, Leentje; Njo, Maria Fransiska; Inzé, Dirk; Bartel, Bonnie; Beeckman, Tom
2012-09-01
The acquisition of water and nutrients by plant roots is a fundamental aspect of agriculture and strongly depends on root architecture. Root branching and expansion of the root system is achieved through the development of lateral roots and is to a large extent controlled by the plant hormone auxin. However, the pleiotropic effects of auxin or auxin-like molecules on root systems complicate the study of lateral root development. Here we describe a small-molecule screen in Arabidopsis thaliana that identified naxillin as what is to our knowledge the first non-auxin-like molecule that promotes root branching. By using naxillin as a chemical tool, we identified a new function for root cap-specific conversion of the auxin precursor indole-3-butyric acid into the active auxin indole-3-acetic acid and uncovered the involvement of the root cap in root branching. Delivery of an auxin precursor in peripheral tissues such as the root cap might represent an important mechanism shaping root architecture.
A role for the root cap in root branching revealed by the non-auxin probe naxillin
De Rybel, Bert; Audenaert, Dominique; Xuan, Wei; Overvoorde, Paul; Strader, Lucia C; Kepinski, Stefan; Hoye, Rebecca; Brisbois, Ronald; Parizot, Boris; Vanneste, Steffen; Liu, Xing; Gilday, Alison; Graham, Ian A; Nguyen, Long; Jansen, Leentje; Njo, Maria Fransiska; Inzé, Dirk; Bartel, Bonnie; Beeckman, Tom
2013-01-01
The acquisition of water and nutrients by plant roots is a fundamental aspect of agriculture and strongly depends on root architecture. Root branching and expansion of the root system is achieved through the development of lateral roots and is to a large extent controlled by the plant hormone auxin. However, the pleiotropic effects of auxin or auxin-like molecules on root systems complicate the study of lateral root development. Here we describe a small-molecule screen in Arabidopsis thaliana that identified naxillin as what is to our knowledge the first non-auxin-like molecule that promotes root branching. By using naxillin as a chemical tool, we identified a new function for root cap-specific conversion of the auxin precursor indole-3-butyric acid into the active auxin indole-3-acetic acid and uncovered the involvement of the root cap in root branching. Delivery of an auxin precursor in peripheral tissues such as the root cap might represent an important mechanism shaping root architecture. PMID:22885787
Luminal mitosis drives epithelial cell dispersal within the branching ureteric bud
Packard, Adam; Georgas, Kylie; Michos, Odyssé; Riccio, Paul; Cebrian, Cristina; Combes, Alexander N.; Ju, Adler; Ferrer-Vaquer, Anna; Hadjantonakis, Anna-Katerina; Zong, Hui; Little, Melissa H.; Costantini, Frank
2013-01-01
Summary The ureteric bud is an epithelial tube that undergoes branching morphogenesis to form the renal collecting system. Though development of a normal kidney depends on proper ureteric bud morphogenesis, the cellular events underlying this process remain obscure. Here, we used time-lapse microscopy together with several genetic labeling methods to observe ureteric bud cell behaviors in developing mouse kidneys. We observed an unexpected cell behavior in the branching tips of the ureteric bud, which we term “mitosis-associated cell dispersal”. Pre-mitotic ureteric tip cells delaminate from the epithelium and divide within the lumen; while one daughter cell retains a basal process, allowing it to reinsert into the epithelium at the site of origin, the other daughter cell reinserts at a position one to three cell diameters away. Given the high rate of cell division in ureteric tips, this cellular behavior causes extensive epithelial cell rearrangements that may contribute to renal branching morphogenesis. PMID:24183650
Control over the branched structures of platinum nanocrystals for electrocatalytic applications.
Ma, Liang; Wang, Chengming; Gong, Ming; Liao, Lingwen; Long, Ran; Wang, Jinguo; Wu, Di; Zhong, Wei; Kim, Moon J; Chen, Yanxia; Xie, Yi; Xiong, Yujie
2012-11-27
Structural control of branched nanocrystals allows tuning two parameters that are critical to their catalytic activity--the surface-to-volume ratio, and the number of atomic steps, ledges, and kinks on surface. In this work, we have developed a simple synthetic system that allows tailoring the numbers of branches in Pt nanocrystals by tuning the concentration of additional HCl. In the synthesis, HCl plays triple functions in tuning branched structures via oxidative etching: (i) the crystallinity of seeds and nanocrystals; (ii) the number of {111} or {100} faces provided for growth sites; (iii) the supply kinetics of freshly formed Pt atoms in solution. As a result, tunable Pt branched structures--tripods, tetrapods, hexapods, and octopods with identical chemical environment--can be rationally synthesized in a single system by simply altering the etching strength. The controllability in branched structures enables to reveal that their electrocatalytic performance can be optimized by constructing complex structures. Among various branched structures, Pt octopods exhibit particularly high activity in formic acid oxidation as compared with their counterparts and commercial Pt/C catalysts. It is anticipated that this work will open a door to design more complex nanostructures and to achieve specific functions for various applications.
Al-Qurainy, F; Khan, S; Nadeem, M; Tarroum, M; Alaklabi, A
2013-03-11
The rare and endangered plants of any country are important genetic resources that often require urgent conservation measures. Assessment of phylogenetic relationships and evaluation of genetic diversity is very important prior to implementation of conservation strategies for saving rare and endangered plant species. We used internal transcribed spacer sequences of nuclear ribosomal DNA for the evaluation of sequence identity from the available taxa in the GenBank database by using the Basic Local Alignment Search Tool (BLAST). Two rare plant species viz, Heliotropium strigosum claded with H. pilosum (98% branch support) and Pancratium tortuosum claded with P. tenuifolium (61% branch support) clearly. However, some species, viz Scadoxus multiflorus, Commiphora myrrha and Senecio hadiensis showed close relationships with more than one species. We conclude that nuclear ribosomal internal transcribed spacer sequences are useful markers for phylogenetic study of these rare plant species in Saudi Arabia.
NASA Astrophysics Data System (ADS)
Lavrik, Olga L.; Busygina, Tatyana V.; Shaburova, Natalya N.; Zibareva, Inna V.
2015-02-01
The multidimensional bibliometric analysis of publications on nanoscience and nanotechnology (NS&NT) produced by the researchers of the Siberian Branch of the Russian Academy of Sciences (SB RAS) in 2007-2012 has shown their growing publication activity and international visibility in the field and the main objects of research such as nanoparticles, nanostructures (nanostructured materials), nanotubes (especially carbon ones), nanocomposites, nanocrystals, nanotechnology, and nanoelectronics and identified the most productive authors and institutes, as well as the most cited publications. It was made using the data from multidisciplinary (Web of Science, Scopus, and Russian Index of Scientific Citation) and specialized (Chemical Abstracts Plus and Inspec) information resources, that is from international (WoS, Scopus, CAPlus, and Inspec) and national (RISC) data bases. The analysis has shown that most of the SB RAS research works on NS&NT are concentrated in Novosibirsk Scientific Centre.
The structure and emerging trends of construction safety management research: a bibliometric review.
Liang, Huakang; Zhang, Shoujian; Su, Yikun
2018-03-29
Recently, construction safety management (CSM) practices and systems have become important topics for stakeholders to take care of human resources. However, few studies have attempted to map the global research on CSM. A comprehensive bibliometric review was conducted in this study based on multiple methods. In total, 1172 CSM-related papers from the Web of Science Core Collection database were examined. The analyses focused on publication year, country-institute, publication source, author and research topics. The results indicated that the USA, China, Australia and the UK took leading positions in CSM research. Two branches of journals were identified, namely the branch of engineering science and that of safety science and social science. Additionally, seven themes together with 28 specific topics were detected to allow researchers to track the main structure and temporal evolution of CSM research. Finally, the main research trends and potential research directions were discussed to guide the future research.
Fractal patterns of fracture in sandwich composite materials under biaxial tension
NASA Astrophysics Data System (ADS)
Fang, Jing; Yao, Xuefeng; Qi, Jia
1996-04-01
The paper presents a successful experiment to generate a fractal pattern of branching cracks in a brittle material sandwiched in ductile plates. A glass sheet bonded between two polycarbonate plates was heated at different levels of temperatures and the stress field due to the difference of thermal coefficients of the materials was solved by combining the results from isochromatic fringes and thermal stress analysis. At a critical degree of temperature, a crack was initiated at a point and soon produced crack branches to release the stored energy. A tree—like fractal patterns of the branch cracks was then developed with the growth of the branches that subsequently produced more branches on their ways of propagation. The fractal dimension of the fracture pattern was evaluated and the mechanism of the fragmentation was analyzed with the help of the residual stress field of isochromatic and isoclinic patterns.
Microvascular Branching as a Determinant of Blood Flow by Intravital Particle Imaging Velocimetry
NASA Technical Reports Server (NTRS)
Parsons-Wingerter, Patricia; McKay, Terri L.; Vickerman, Mary B.; Wernet, Mark P.; Myers, Jerry G.; Radhakrishnan, Krishnan
2007-01-01
The effects of microvascular branching on blood flow were investigated in vivo by microscopic particle imaging velocimetry (micro-PIV). We use micro-PIV to measure blood flow by tracking red blood cells (RBC) as the moving particles. Velocity flow fields, including flow pulsatility, were analyzed for the first four branching orders of capillaries, postcapillary venules and small veins of the microvascular network within the developing avian yolksac at embryonic day 5 (E5). Increasing volumetric flowrates were obtained from parabolic laminar flow profiles as a function of increasing vessel diameter and branching order. Maximum flow velocities increased approximately twenty-fold as the function of increasing vessel diameter and branching order compared to flow velocities of 100 - 150 micron/sec in the capillaries. Results from our study will be useful for the increased understanding of blood flow within anastomotic, heterogeneous microvascular networks.
The US Defense Industrial Base: Past, Present, and Future
2008-01-01
Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to a penalty for...insightful analyses to senior decision makers in the executive and legislative branches, as well as to the media and the broader national security...contingen-cies in order to determine what resources will be required, and how they should be ap-portioned among forces and capabilities. uS MiLitary
1995-01-01
rainfall runoff model, DR&& to Bear Branch watershed, Murfreesboro, Tennessee .......... 37 Seepage and spring inventory reconnaissance and base-flow... bearing rocks in the Valley and Ridge, Blue Ridge, and Piedmont physiographic provinces, and covers parts of eight states from New Jersey to Alabama...100 feet in diameter and about 250 feet deep. It penetrates three water- bearing units of carbonate origin (the shallow aquifer, the Manchester aquifer
Surface water records of Colorado, 1961
U.S. Geological Survey, Water Resources Division
1961-01-01
The surface-water records for the 1961 water year for gaging stations and miscellaneous sites within the State of Colorado are given in this report. For convenience there are also included records for a few pertinent gaging stations in bordering States. The records were collected and computed by the Water Resources Division of the U.S. Geological Survey, under the direction of W. T. Miller, district engineer, Surface Water Branch, succeeded by J. W. Odell.
Sesquinaries, Magnetics and Atmospheres: Studies of the Terrestrial Moons and Exoplanets
2016-12-01
support provided by Red Sky Research, LLC. Computational support was provided by the NASA Ames Mission Design Division (Code RD) for research...Systems Branch (Code SST), NASA Ames Research Center, provided supercomputer access and computational resources for the work in Chapter 5. I owe a...huge debt of gratitude to Dr. Pete Worden, Dr. Steve Zornetzer, Dr. Alan Weston ( NASA ), and Col. Carol Welsch, Lt. Col Joe Nance and Lt. Col Brian
Experimental Resource Allocation for Statistical Simulation of Fretting Fatigue Problem (Preprint)
2012-08-01
Metals Branch Structural Materials Division Harry R. Millwater , Carolina Dubinsky, and Gulshan Singh University of Texas at San Antonio...GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62102F 6. AUTHOR(S) Patrick Golden (AFRL/RXCM) Harry R. Millwater , Carolina Dubinsky, and Gulshan...Safety. 1996;54(2-3):133-144 [5] Golden, PJ, Millwater HR and Yang X. Probabilistic Fretting Fatigue Life Prediction of Ti-6Al-4V. International Journal
Assessing Army Professional Forums Metrics for Effectiveness and Impact
2006-10-01
erso n n el ........................................................................................................................... 9 Functional R...treated like its analogue, a 1-5 ordinal rating scale. 21 .!: 0’ ) El ~ --S cl 0 P. 0~\\ E) m .0 ý ýg.ua+ co 0 - ~ a~ >V ~a 00 Ln 1cc) r.a 0 ~ ~ Q) u o u. 0... Broncos , etc.) have forums in AKO that post trends. These may be helpful resources. Occasionally, branch-specific professional publications, such as
1983-12-01
tests were conducted for the Maline Creek urban study recently completed by the St. Louis District. Those tests showed that variations in the...were not performed .or expansion and contraction coefficients used in this study. However, such tests were conducted for the Maline Creek urban study...Conservation, letter to Mr. Jack Rasmussen, Chief of Planning Branch, St. -Louis District, Reference to Maline Creek Study, dated 18 June 1979. Griffin, C
DOE Office of Scientific and Technical Information (OSTI.GOV)
Choi, Jin Woo; Kim, Hyo-Cheol, E-mail: angiointervention@gmail.com; Chung, Jin Wook
Purpose: This study was designed to evaluate the radiologic findings and imaging response of chemoembolization via branches of the splenic artery in patients with hepatocellular carcinoma (HCC). Methods: From January 2001 to July 2010, we observed tumor staining supplied by branches of the splenic artery in 34 (0.6%) of 5,413 patients with HCC. Computed tomography (CT) scans and digital subtraction angiograms of these patients were retrospectively reviewed in consensus by two investigators. Results: A total of 39 tumor feeding-vessels in 34 patients were identified: omental branches from the left gastroepiploic artery (n = 5), branches from the short gastric arterymore » (n = 9), and omental branches directly from the splenic artery (n = 25). Branches of the splenic artery that supplied tumors were revealed on the celiac angiogram in 29 (85%) of 34 patients and were detected on pre-procedure CT images in 27 (79%) of 34 patients. Selective chemoembolization was achieved in 38 of 39 tumor-feeding vessels. Complete or partial response of the tumor fed by branches of the splenic artery, as depicted on follow-up CT scans, was achieved in 21 (62%) patients. No patient developed severe complications directly related to chemoembolization via branches of the splenic artery. Conclusions: Omental branches directly from the splenic artery are common tumor-feeding vessels of the splenic artery in cases of advanced HCC with multiple previous chemoembolizations. Tumor-feeding vessels of the splenic artery are usually visualized on the celiac angiogram or CT scan, and chemoembolization through them can be safely performed in most patients.« less
Differential Effects of RET and TRKB on Axonal Branching and Survival of Parasympathetic Neurons
Simpson, Julie; Keefe, Julie; Nishi, Rae
2014-01-01
Interactions between neurons and their targets of innervation influence many aspects of neural development. To examine how synaptic activity interacts with neurotrophic signaling, we determined the effects of blocking neuromuscular transmission on survival and axonal outgrowth of ciliary neurons from the embryonic chicken ciliary ganglion. Ciliary neurons undergo a period of cell loss due to programmed cell death between embryonic Days (E) 8 and 14 and they innervate the striated muscle of the iris. The nicotinic antagonist d-tubocurarine (dTC) induces an increase in branching measured by counting neurofilament-positive voxels (NF-VU) in the iris between E14–17 while reducing ciliary neuron survival. Blocking ganglionic transmission with dihyro-β-erythroidin and α-methyllycacontine does not mimic dTC. At E8, many trophic factors stimulate neurite outgrowth and branching of neurons placed in cell culture; however, at E13, only GDNF stimulates branching selectively in cultured ciliary neurons. The GDNF-induced branching at E13 could be inhibited by BDNF. Blocking ret signaling in vivo with a dominant negative (dn)ret decreases survival of ciliary and choroid neurons at E14 and prevents dTC induced increases in NF-VU in the iris at E17. Blocking TRKB signaling with dn TRKB increases NF-VU in the iris at E17 and decreases neuronal survival at E17, but not at E14. Thus, RET promotes survival during programmed cell death in the ciliary ganglion and contributes to promoting branching when synaptic transmission is blocked while TRKB inhibits branching and promotes maintenance of neuronal survival. These studies highlight the multifunctional nature of trophic molecule function during neuronal development. PMID:22648743
Gold, Elspeth; Zellhuber-McMillan, Sylvia; Risbridger, Gail; Marino, Francesco Elia
2017-01-01
Activins and inhibins, members of the TGF-β superfamily, are growth and differentiation factors involved in the regulation of several biological processes, including reproduction, development, and fertility. Previous studies have shown that the activin-β A subunit plays a pivotal role in prostate development. Activin-A inhibits branching morphogenesis in the developing prostate, and its expression is associated with increased apoptosis in the adult prostate. Follistatin, a structurally unrelated protein to activins, is an antagonist of activin-A. A balance between endogenous activin-A and follistatin is required to maintain prostatic branching morphogenesis. Deregulation of this balance leads to branching inhibition or excessive branching and increased maturation of the stroma surrounding the differentiating epithelial ducts. Recent work identified another member of the TGF-β superfamily, the activin-β C subunit, as a novel antagonist of activin-A. Over-expression of activin-C (β C -β C ) alters prostate homeostasis, by interfering with the activin-A signaling. The current study characterized the spatiotemporal localization of activin-A, activin-C and follistatin in the adult and developing mouse prostate using immunohistochemical analysis. Results showed activin-C and follistatin are differentially expressed during prostate development and suggested that the antagonistic property of follistatin is secondary to the action of activin-C. In conclusion, the present study provides evidence to support a role of activin-C in prostate development and provides new insights in the spatiotemporal localization of activins and their antagonists during mouse prostate development. Copyright © 2017 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Elbanna, A. E.
2013-12-01
Numerous field and experimental observations suggest that faults surfaces are rough at multiple scales and tend to produce a wide range of branch sizes ranging from micro-branching to large scale secondary faults. The development and evolution of fault roughness and branching is believed to play an important role in rupture dynamics and energy partitioning. Previous work by several groups has succeeded in determining conditions under which a main rupture may branch into a secondary fault. Recently, there great progress has been made in investigating rupture propagation on rough faults with and without off-fault plasticity. Nonetheless, in most of these models the heterogeneity, whether the roughness profile or the secondary faults orientation, was built into the system from the beginning and consequently the final outcome depends strongly on the initial conditions. Here we introduce an adaptive mesh technique for modeling mode-II crack propagation on slip weakening frictional interfaces. We use a Finite Element Framework with random mesh topology that adapts to crack dynamics through element splitting and sequential insertion of frictional interfaces dictated by the failure criterion. This allows the crack path to explore non-planar paths and develop the roughness profile that is most compatible with the dynamical constraints. It also enables crack branching at different scales. We quantify energy dissipation due to the roughening process and small scale branching. We compare the results of our model to a reference case for propagation on a planar fault. We show that the small scale processes of roughening and branching influence many characteristics of the rupture propagation including the energy partitioning, rupture speed and peak slip rates. We also estimate the fracture energy required for propagating a crack on a planar fault that will be required to produce comparable results. We anticipate that this modeling approach provides an attractive methodology that complements the current efforts in modeling off-fault plasticity and damage.
Branch: an interactive, web-based tool for testing hypotheses and developing predictive models.
Gangavarapu, Karthik; Babji, Vyshakh; Meißner, Tobias; Su, Andrew I; Good, Benjamin M
2016-07-01
Branch is a web application that provides users with the ability to interact directly with large biomedical datasets. The interaction is mediated through a collaborative graphical user interface for building and evaluating decision trees. These trees can be used to compose and test sophisticated hypotheses and to develop predictive models. Decision trees are built and evaluated based on a library of imported datasets and can be stored in a collective area for sharing and re-use. Branch is hosted at http://biobranch.org/ and the open source code is available at http://bitbucket.org/sulab/biobranch/ asu@scripps.edu or bgood@scripps.edu Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.
Scholl, David William
1978-01-01
The Geological Survey 's marine geology investigations in the Pacific-Arctic area are presented in this report in the context of the underlying socio-economic problem of expanding the domestic production of oil and gas and other mineral and hard- and soft-rock resources while maintaining acceptable standards in the marine environment. The primary mission of the Survey 's Pacific-Arctic Branch of Marine Geology is to provide scientifically interpreted information about the (1) resource potential, (2) geo-environmental setting, and (3) overall geologic characteristics of the continental margins (that is, the continental shelf, slope and rise) and adjacent deeper water and shallower coastal areas off California, Oregon, Washington, Alaska and Hawaii and also, where it is of interest to the U.S. Government, more remote deep-sea areas of the Pacific-Arctic realm. (Sinha-OEIS)
Improved synthesis and characterization of saturated branched-chain fatty acid isomers
USDA-ARS?s Scientific Manuscript database
The development of viable technologies for producing green products from renewable fats and oils is highly desirable since such materials can serve as replacements for non-renewable and poorly biodegradable petroleum-based products. Mixtures of saturated branched-chain fatty acid isomers (sbc-FAs),...
Møller, Marie S; Goh, Yong Jun; Rasmussen, Kasper Bøwig; Cypryk, Wojciech; Celebioglu, Hasan Ufuk; Klaenhammer, Todd R; Svensson, Birte; Abou Hachem, Maher
2017-06-15
Of the few predicted extracellular glycan-active enzymes, glycoside hydrolase family 13 subfamily 14 (GH13_14) pullulanases are the most common in human gut lactobacilli. These enzymes share a unique modular organization, not observed in other bacteria, featuring a catalytic module, two starch binding modules, a domain of unknown function, and a C-terminal surface layer association protein (SLAP) domain. Here, we explore the specificity of a representative of this group of pullulanases, Lactobacillus acidophilus Pul13_14 ( La Pul13_14), and its role in branched α-glucan metabolism in the well-characterized Lactobacillus acidophilus NCFM, which is widely used as a probiotic. Growth experiments with L. acidophilus NCFM on starch-derived branched substrates revealed a preference for α-glucans with short branches of about two to three glucosyl moieties over amylopectin with longer branches. Cell-attached debranching activity was measurable in the presence of α-glucans but was repressed by glucose. The debranching activity is conferred exclusively by La Pul13_14 and is abolished in a mutant strain lacking a functional La Pul13_14 gene. Hydrolysis kinetics of recombinant La Pul13_14 confirmed the preference for short-branched α-glucan oligomers consistent with the growth data. Curiously, this enzyme displayed the highest catalytic efficiency and the lowest K m reported for a pullulanase. Inhibition kinetics revealed mixed inhibition by β-cyclodextrin, suggesting the presence of additional glucan binding sites besides the active site of the enzyme, which may contribute to the unprecedented substrate affinity. The enzyme also displays high thermostability and higher activity in the acidic pH range, reflecting adaptation to the physiologically challenging conditions in the human gut. IMPORTANCE Starch is one of the most abundant glycans in the human diet. Branched α-1,6-glucans in dietary starch and glycogen are nondegradable by human enzymes and constitute a metabolic resource for the gut microbiota. The role of health-beneficial lactobacilli prevalent in the human small intestine in starch metabolism remains unexplored in contrast to colonic bacterial residents. This study highlights the pivotal role of debranching enzymes in the breakdown of starchy branched α-glucan oligomers (α-limit dextrins) by human gut lactobacilli exemplified by Lactobacillus acidophilus NCFM, which is one of the best-characterized strains used as probiotics. Our data bring novel insight into the metabolic preference of L. acidophilus for α-glucans with short α-1,6-branches. The unprecedented affinity of the debranching enzyme that confers growth on these substrates reflects its adaptation to the nutrient-competitive gut ecological niche and constitutes a potential advantage in cross-feeding from human and bacterial dietary starch metabolism. Copyright © 2017 American Society for Microbiology.
Møller, Marie S.; Rasmussen, Kasper Bøwig; Cypryk, Wojciech; Celebioglu, Hasan Ufuk; Klaenhammer, Todd R.; Svensson, Birte
2017-01-01
ABSTRACT Of the few predicted extracellular glycan-active enzymes, glycoside hydrolase family 13 subfamily 14 (GH13_14) pullulanases are the most common in human gut lactobacilli. These enzymes share a unique modular organization, not observed in other bacteria, featuring a catalytic module, two starch binding modules, a domain of unknown function, and a C-terminal surface layer association protein (SLAP) domain. Here, we explore the specificity of a representative of this group of pullulanases, Lactobacillus acidophilus Pul13_14 (LaPul13_14), and its role in branched α-glucan metabolism in the well-characterized Lactobacillus acidophilus NCFM, which is widely used as a probiotic. Growth experiments with L. acidophilus NCFM on starch-derived branched substrates revealed a preference for α-glucans with short branches of about two to three glucosyl moieties over amylopectin with longer branches. Cell-attached debranching activity was measurable in the presence of α-glucans but was repressed by glucose. The debranching activity is conferred exclusively by LaPul13_14 and is abolished in a mutant strain lacking a functional LaPul13_14 gene. Hydrolysis kinetics of recombinant LaPul13_14 confirmed the preference for short-branched α-glucan oligomers consistent with the growth data. Curiously, this enzyme displayed the highest catalytic efficiency and the lowest Km reported for a pullulanase. Inhibition kinetics revealed mixed inhibition by β-cyclodextrin, suggesting the presence of additional glucan binding sites besides the active site of the enzyme, which may contribute to the unprecedented substrate affinity. The enzyme also displays high thermostability and higher activity in the acidic pH range, reflecting adaptation to the physiologically challenging conditions in the human gut. IMPORTANCE Starch is one of the most abundant glycans in the human diet. Branched α-1,6-glucans in dietary starch and glycogen are nondegradable by human enzymes and constitute a metabolic resource for the gut microbiota. The role of health-beneficial lactobacilli prevalent in the human small intestine in starch metabolism remains unexplored in contrast to colonic bacterial residents. This study highlights the pivotal role of debranching enzymes in the breakdown of starchy branched α-glucan oligomers (α-limit dextrins) by human gut lactobacilli exemplified by Lactobacillus acidophilus NCFM, which is one of the best-characterized strains used as probiotics. Our data bring novel insight into the metabolic preference of L. acidophilus for α-glucans with short α-1,6-branches. The unprecedented affinity of the debranching enzyme that confers growth on these substrates reflects its adaptation to the nutrient-competitive gut ecological niche and constitutes a potential advantage in cross-feeding from human and bacterial dietary starch metabolism. PMID:28411221
Lykov, Kirill; Li, Xuejin; Lei, Huan; ...
2015-08-28
When blood flows through a bifurcation, red blood cells (RBCs) travel into side branches at different hematocrit levels, and it is even possible that all RBCs enter into one branch only, leading to a complete separation of plasma and R- BCs. To quantify this phenomenon via particle-based mesoscopic simulations, we developed a general framework for open boundary conditions in multiphase flows that is effective even for high hematocrit levels. The inflow at the inlet is duplicated from a fully developed flow generated in a pilot simulation with periodic boundary conditions. The outflow is controlled by adaptive forces to maintain themore » flow rate and velocity gradient at fixed values, while the particles leaving the arteriole at the outlet are removed from the system. Upon valida- tion of this approach, we performed systematic 3D simulations to study plasma skimming in arterioles of diameters 20 to 32 microns. For a flow rate ratio 6:1 at the branches, we observed the \\all-or-nothing" phenomenon with plasma only entering the low flow rate branch. We then simulated blood-plasma separation in arteriolar bifurcations with different bifurcation angles and same diameter of the daughter branches. Our simulations predict a significant increase in RBC flux through the main daughter branch as the bifurcation angle is increased. Lastly, we demonstrated the new methodology for simulating blood flow in ves- sels with multiple inlets and outlets, constructed using an angiogenesis model.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lykov, Kirill; Li, Xuejin; Lei, Huan
When blood flows through a bifurcation, red blood cells (RBCs) travel into side branches at different hematocrit levels, and it is even possible that all RBCs enter into one branch only, leading to a complete separation of plasma and R- BCs. To quantify this phenomenon via particle-based mesoscopic simulations, we developed a general framework for open boundary conditions in multiphase flows that is effective even for high hematocrit levels. The inflow at the inlet is duplicated from a fully developed flow generated in a pilot simulation with periodic boundary conditions. The outflow is controlled by adaptive forces to maintain themore » flow rate and velocity gradient at fixed values, while the particles leaving the arteriole at the outlet are removed from the system. Upon valida- tion of this approach, we performed systematic 3D simulations to study plasma skimming in arterioles of diameters 20 to 32 microns. For a flow rate ratio 6:1 at the branches, we observed the \\all-or-nothing" phenomenon with plasma only entering the low flow rate branch. We then simulated blood-plasma separation in arteriolar bifurcations with different bifurcation angles and same diameter of the daughter branches. Our simulations predict a significant increase in RBC flux through the main daughter branch as the bifurcation angle is increased. Lastly, we demonstrated the new methodology for simulating blood flow in ves- sels with multiple inlets and outlets, constructed using an angiogenesis model.« less
Lykov, Kirill; Li, Xuejin; Lei, Huan; Pivkin, Igor V; Karniadakis, George Em
2015-08-01
When blood flows through a bifurcation, red blood cells (RBCs) travel into side branches at different hematocrit levels, and it is even possible that all RBCs enter into one branch only, leading to a complete separation of plasma and RBCs. To quantify this phenomenon via particle-based mesoscopic simulations, we developed a general framework for open boundary conditions in multiphase flows that is effective even for high hematocrit levels. The inflow at the inlet is duplicated from a fully developed flow generated in a pilot simulation with periodic boundary conditions. The outflow is controlled by adaptive forces to maintain the flow rate and velocity gradient at fixed values, while the particles leaving the arteriole at the outlet are removed from the system. Upon validation of this approach, we performed systematic 3D simulations to study plasma skimming in arterioles of diameters 20 to 32 microns. For a flow rate ratio 6:1 at the branches, we observed the "all-or-nothing" phenomenon with plasma only entering the low flow rate branch. We then simulated blood-plasma separation in arteriolar bifurcations with different bifurcation angles and same diameter of the daughter branches. Our simulations predict a significant increase in RBC flux through the main daughter branch as the bifurcation angle is increased. Finally, we demonstrated the effectiveness of the new methodology in simulations of blood flow in vessels with multiple inlets and outlets, constructed using an angiogenesis model.
Niizeki, Takeshi; Ikeno, Eiichiro; Kubota, Isao
2017-01-01
Patient: Male, 54 Final Diagnosis: Old myocardial infarction Symptoms: Lower extremity swelling • respiratory distress Medication: — Clinical Procedure: Success Specialty: Cardiology Objective: Unusual setting of medical care Background: Success rates for treatment of chronic total occlusion (CTO) have dramatically improved in recent years with the development of new CTO guidewires and development of new techniques such as the retrograde approach. In the antegrade approach, a guidewire is occasionally passed through a side branch despite successful wire crossing of the CTO lesion. In order to pass a wire through the main artery, there are a few side branch techniques such as a reverse wire technique. Case Report: A 54-year-old man with symptoms of heart failure was admitted to our hospital. Coronary angiography showed CTO of the proximal left anterior descending artery. Percutaneous coronary intervention with an antegrade approach was started. We succeeded in passing the wire through a side branch but not the main artery. Unfortunately, a reverse wire technique failed in this case. Next, the wire passed through a side branch was exchanged with the Soutenir CV, and a retrograde approach was started. The wire crossing from retrograde was entwined around the Soutenir CV. After that, the retrograde wire was snared and guided to the antegrade guiding catheter, which resulted in successful wiring into the main artery easily. Conclusions: The side branch technique using the Soutenir CV may be an effective strategy in some cases. PMID:28082733