Database resources of the National Center for Biotechnology Information
Wheeler, David L.; Barrett, Tanya; Benson, Dennis A.; Bryant, Stephen H.; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M.; DiCuccio, Michael; Edgar, Ron; Federhen, Scott; Geer, Lewis Y.; Helmberg, Wolfgang; Kapustin, Yuri; Kenton, David L.; Khovayko, Oleg; Lipman, David J.; Madden, Thomas L.; Maglott, Donna R.; Ostell, James; Pruitt, Kim D.; Schuler, Gregory D.; Schriml, Lynn M.; Sequeira, Edwin; Sherry, Stephen T.; Sirotkin, Karl; Souvorov, Alexandre; Starchenko, Grigory; Suzek, Tugba O.; Tatusov, Roman; Tatusova, Tatiana A.; Wagner, Lukas; Yaschenko, Eugene
2006-01-01
In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI's Web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central, Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Electronic PCR, OrfFinder, Spidey, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, Cancer Chromosomes, Entrez Genomes and related tools, the Map Viewer, Model Maker, Evidence Viewer, Clusters of Orthologous Groups, Retroviral Genotyping Tools, HIV-1, Human Protein Interaction Database, SAGEmap, Gene Expression Omnibus, Entrez Probe, GENSAT, Online Mendelian Inheritance in Man, Online Mendelian Inheritance in Animals, the Molecular Modeling Database, the Conserved Domain Database, the Conserved Domain Architecture Retrieval Tool and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized datasets. All of the resources can be accessed through the NCBI home page at: . PMID:16381840
Database resources of the National Center for Biotechnology Information.
Wheeler, David L; Barrett, Tanya; Benson, Dennis A; Bryant, Stephen H; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M; DiCuccio, Michael; Edgar, Ron; Federhen, Scott; Geer, Lewis Y; Kapustin, Yuri; Khovayko, Oleg; Landsman, David; Lipman, David J; Madden, Thomas L; Maglott, Donna R; Ostell, James; Miller, Vadim; Pruitt, Kim D; Schuler, Gregory D; Sequeira, Edwin; Sherry, Steven T; Sirotkin, Karl; Souvorov, Alexandre; Starchenko, Grigory; Tatusov, Roman L; Tatusova, Tatiana A; Wagner, Lukas; Yaschenko, Eugene
2007-01-01
In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI's Web site. NCBI resources include Entrez, the Entrez Programming Utilities, My NCBI, PubMed, PubMed Central, Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link(BLink), Electronic PCR, OrfFinder, Spidey, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, Cancer Chromosomes, Entrez Genome, Genome Project and related tools, the Trace and Assembly Archives, the Map Viewer, Model Maker, Evidence Viewer, Clusters of Orthologous Groups (COGs), Viral Genotyping Tools, Influenza Viral Resources, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus (GEO), Entrez Probe, GENSAT, Online Mendelian Inheritance in Man (OMIM), Online Mendelian Inheritance in Animals (OMIA), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART) and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. These resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.
Database resources of the National Center for Biotechnology Information
Wheeler, David L.; Barrett, Tanya; Benson, Dennis A.; Bryant, Stephen H.; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M.; DiCuccio, Michael; Edgar, Ron; Federhen, Scott; Feolo, Michael; Geer, Lewis Y.; Helmberg, Wolfgang; Kapustin, Yuri; Khovayko, Oleg; Landsman, David; Lipman, David J.; Madden, Thomas L.; Maglott, Donna R.; Miller, Vadim; Ostell, James; Pruitt, Kim D.; Schuler, Gregory D.; Shumway, Martin; Sequeira, Edwin; Sherry, Steven T.; Sirotkin, Karl; Souvorov, Alexandre; Starchenko, Grigory; Tatusov, Roman L.; Tatusova, Tatiana A.; Wagner, Lukas; Yaschenko, Eugene
2008-01-01
In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data available through NCBI's web site. NCBI resources include Entrez, the Entrez Programming Utilities, My NCBI, PubMed, PubMed Central, Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link, Electronic PCR, OrfFinder, Spidey, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, Cancer Chromosomes, Entrez Genome, Genome Project and related tools, the Trace, Assembly, and Short Read Archives, the Map Viewer, Model Maker, Evidence Viewer, Clusters of Orthologous Groups, Influenza Viral Resources, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus, Entrez Probe, GENSAT, Database of Genotype and Phenotype, Online Mendelian Inheritance in Man, Online Mendelian Inheritance in Animals, the Molecular Modeling Database, the Conserved Domain Database, the Conserved Domain Architecture Retrieval Tool and the PubChem suite of small molecule databases. Augmenting the web applications are custom implementations of the BLAST program optimized to search specialized data sets. These resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov. PMID:18045790
Database resources of the National Center for Biotechnology Information.
Sayers, Eric W; Barrett, Tanya; Benson, Dennis A; Bryant, Stephen H; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M; DiCuccio, Michael; Edgar, Ron; Federhen, Scott; Feolo, Michael; Geer, Lewis Y; Helmberg, Wolfgang; Kapustin, Yuri; Landsman, David; Lipman, David J; Madden, Thomas L; Maglott, Donna R; Miller, Vadim; Mizrachi, Ilene; Ostell, James; Pruitt, Kim D; Schuler, Gregory D; Sequeira, Edwin; Sherry, Stephen T; Shumway, Martin; Sirotkin, Karl; Souvorov, Alexandre; Starchenko, Grigory; Tatusova, Tatiana A; Wagner, Lukas; Yaschenko, Eugene; Ye, Jian
2009-01-01
In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central, Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Electronic PCR, OrfFinder, Spidey, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, Cancer Chromosomes, Entrez Genomes and related tools, the Map Viewer, Model Maker, Evidence Viewer, Clusters of Orthologous Groups (COGs), Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus (GEO), Entrez Probe, GENSAT, Online Mendelian Inheritance in Man (OMIM), Online Mendelian Inheritance in Animals (OMIA), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART) and the PubChem suite of small molecule databases. Augmenting many of the web applications is custom implementation of the BLAST program optimized to search specialized data sets. All of the resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.
Database resources of the National Center for Biotechnology Information.
Sayers, Eric W; Barrett, Tanya; Benson, Dennis A; Bolton, Evan; Bryant, Stephen H; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M; DiCuccio, Michael; Federhen, Scott; Feolo, Michael; Fingerman, Ian M; Geer, Lewis Y; Helmberg, Wolfgang; Kapustin, Yuri; Landsman, David; Lipman, David J; Lu, Zhiyong; Madden, Thomas L; Madej, Tom; Maglott, Donna R; Marchler-Bauer, Aron; Miller, Vadim; Mizrachi, Ilene; Ostell, James; Panchenko, Anna; Phan, Lon; Pruitt, Kim D; Schuler, Gregory D; Sequeira, Edwin; Sherry, Stephen T; Shumway, Martin; Sirotkin, Karl; Slotta, Douglas; Souvorov, Alexandre; Starchenko, Grigory; Tatusova, Tatiana A; Wagner, Lukas; Wang, Yanli; Wilbur, W John; Yaschenko, Eugene; Ye, Jian
2011-01-01
In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI Web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central (PMC), Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Primer-BLAST, COBALT, Electronic PCR, OrfFinder, Splign, ProSplign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, dbVar, Epigenomics, Cancer Chromosomes, Entrez Genomes and related tools, the Map Viewer, Model Maker, Evidence Viewer, Trace Archive, Sequence Read Archive, Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus (GEO), Entrez Probe, GENSAT, Online Mendelian Inheritance in Man (OMIM), Online Mendelian Inheritance in Animals (OMIA), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), IBIS, Biosystems, Peptidome, OMSSA, Protein Clusters and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.
Plant Genome Resources at the National Center for Biotechnology Information
Wheeler, David L.; Smith-White, Brian; Chetvernin, Vyacheslav; Resenchuk, Sergei; Dombrowski, Susan M.; Pechous, Steven W.; Tatusova, Tatiana; Ostell, James
2005-01-01
The National Center for Biotechnology Information (NCBI) integrates data from more than 20 biological databases through a flexible search and retrieval system called Entrez. A core Entrez database, Entrez Nucleotide, includes GenBank and is tightly linked to the NCBI Taxonomy database, the Entrez Protein database, and the scientific literature in PubMed. A suite of more specialized databases for genomes, genes, gene families, gene expression, gene variation, and protein domains dovetails with the core databases to make Entrez a powerful system for genomic research. Linked to the full range of Entrez databases is the NCBI Map Viewer, which displays aligned genetic, physical, and sequence maps for eukaryotic genomes including those of many plants. A specialized plant query page allow maps from all plant genomes covered by the Map Viewer to be searched in tandem to produce a display of aligned maps from several species. PlantBLAST searches against the sequences shown in the Map Viewer allow BLAST alignments to be viewed within a genomic context. In addition, precomputed sequence similarities, such as those for proteins offered by BLAST Link, enable fluid navigation from unannotated to annotated sequences, quickening the pace of discovery. NCBI Web pages for plants, such as Plant Genome Central, complete the system by providing centralized access to NCBI's genomic resources as well as links to organism-specific Web pages beyond NCBI. PMID:16010002
EntrezAJAX: direct web browser access to the Entrez Programming Utilities.
Loman, Nicholas J; Pallen, Mark J
2010-06-21
Web applications for biology and medicine often need to integrate data from Entrez services provided by the National Center for Biotechnology Information. However, direct access to Entrez from a web browser is not possible due to 'same-origin' security restrictions. The use of "Asynchronous JavaScript and XML" (AJAX) to create rich, interactive web applications is now commonplace. The ability to access Entrez via AJAX would be advantageous in the creation of integrated biomedical web resources. We describe EntrezAJAX, which provides access to Entrez eUtils and is able to circumvent same-origin browser restrictions. EntrezAJAX is easily implemented by JavaScript developers and provides identical functionality as Entrez eUtils as well as enhanced functionality to ease development. We provide easy-to-understand developer examples written in JavaScript to illustrate potential uses of this service. For the purposes of speed, reliability and scalability, EntrezAJAX has been deployed on Google App Engine, a freely available cloud service. The EntrezAJAX webpage is located at http://entrezajax.appspot.com/
EntrezAJAX: direct web browser access to the Entrez Programming Utilities
2010-01-01
Web applications for biology and medicine often need to integrate data from Entrez services provided by the National Center for Biotechnology Information. However, direct access to Entrez from a web browser is not possible due to 'same-origin' security restrictions. The use of "Asynchronous JavaScript and XML" (AJAX) to create rich, interactive web applications is now commonplace. The ability to access Entrez via AJAX would be advantageous in the creation of integrated biomedical web resources. We describe EntrezAJAX, which provides access to Entrez eUtils and is able to circumvent same-origin browser restrictions. EntrezAJAX is easily implemented by JavaScript developers and provides identical functionality as Entrez eUtils as well as enhanced functionality to ease development. We provide easy-to-understand developer examples written in JavaScript to illustrate potential uses of this service. For the purposes of speed, reliability and scalability, EntrezAJAX has been deployed on Google App Engine, a freely available cloud service. The EntrezAJAX webpage is located at http://entrezajax.appspot.com/ PMID:20565938
Marenco, Luis; Ascoli, Giorgio A; Martone, Maryann E; Shepherd, Gordon M; Miller, Perry L
2008-09-01
This paper describes the NIF LinkOut Broker (NLB) that has been built as part of the Neuroscience Information Framework (NIF) project. The NLB is designed to coordinate the assembly of links to neuroscience information items (e.g., experimental data, knowledge bases, and software tools) that are (1) accessible via the Web, and (2) related to entries in the National Center for Biotechnology Information's (NCBI's) Entrez system. The NLB collects these links from each resource and passes them to the NCBI which incorporates them into its Entrez LinkOut service. In this way, an Entrez user looking at a specific Entrez entry can LinkOut directly to related neuroscience information. The information stored in the NLB can also be utilized in other ways. A second approach, which is operational on a pilot basis, is for the NLB Web server to create dynamically its own Web page of LinkOut links for each NCBI identifier in the NLB database. This approach can allow other resources (in addition to the NCBI Entrez) to LinkOut to related neuroscience information. The paper describes the current NLB system and discusses certain design issues that arose during its implementation.
Ascoli, Giorgio A.; Martone, Maryann E.; Shepherd, Gordon M.; Miller, Perry L.
2009-01-01
This paper describes the NIF LinkOut Broker (NLB) that has been built as part of the Neuroscience Information Framework (NIF) project. The NLB is designed to coordinate the assembly of links to neuroscience information items (e.g., experimental data, knowledge bases, and software tools) that are (1) accessible via the Web, and (2) related to entries in the National Center for Biotechnology Information’s (NCBI’s) Entrez system. The NLB collects these links from each resource and passes them to the NCBI which incorporates them into its Entrez LinkOut service. In this way, an Entrez user looking at a specific Entrez entry can LinkOut directly to related neuroscience information. The information stored in the NLB can also be utilized in other ways. A second approach, which is operational on a pilot basis, is for the NLB Web server to create dynamically its own Web page of LinkOut links for each NCBI identifier in the NLB database. This approach can allow other resources (in addition to the NCBI Entrez) to LinkOut to related neuroscience information. The paper describes the current NLB system and discusses certain design issues that arose during its implementation. PMID:18975149
Database resources of the National Center for Biotechnology Information: 2002 update
Wheeler, David L.; Church, Deanna M.; Lash, Alex E.; Leipe, Detlef D.; Madden, Thomas L.; Pontius, Joan U.; Schuler, Gregory D.; Schriml, Lynn M.; Tatusova, Tatiana A.; Wagner, Lukas; Rapp, Barbara A.
2002-01-01
In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources that operate on the data in GenBank and a variety of other biological data made available through NCBI’s web site. NCBI data retrieval resources include Entrez, PubMed, LocusLink and the Taxonomy Browser. Data analysis resources include BLAST, Electronic PCR, OrfFinder, RefSeq, UniGene, HomoloGene, Database of Single Nucleotide Polymorphisms (dbSNP), Human Genome Sequencing, Human MapViewer, Human¡VMouse Homology Map, Cancer Chromosome Aberration Project (CCAP), Entrez Genomes, Clusters of Orthologous Groups (COGs) database, Retroviral Genotyping Tools, SAGEmap, Gene Expression Omnibus (GEO), Online Mendelian Inheritance in Man (OMIM), the Molecular Modeling Database (MMDB) and the Conserved Domain Database (CDD). Augmenting many of the web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of the resources can be accessed through the NCBI home page at http://www.ncbi.nlm.nih.gov. PMID:11752242
Database resources of the National Center for Biotechnology Information
Wheeler, David L.; Church, Deanna M.; Lash, Alex E.; Leipe, Detlef D.; Madden, Thomas L.; Pontius, Joan U.; Schuler, Gregory D.; Schriml, Lynn M.; Tatusova, Tatiana A.; Wagner, Lukas; Rapp, Barbara A.
2001-01-01
In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources that operate on the data in GenBank and a variety of other biological data made available through NCBI’s Web site. NCBI data retrieval resources include Entrez, PubMed, LocusLink and the Taxonomy Browser. Data analysis resources include BLAST, Electronic PCR, OrfFinder, RefSeq, UniGene, HomoloGene, Database of Single Nucleotide Polymorphisms (dbSNP), Human Genome Sequencing, Human MapViewer, GeneMap’99, Human–Mouse Homology Map, Cancer Chromosome Aberration Project (CCAP), Entrez Genomes, Clusters of Orthologous Groups (COGs) database, Retroviral Genotyping Tools, Cancer Genome Anatomy Project (CGAP), SAGEmap, Gene Expression Omnibus (GEO), Online Mendelian Inheritance in Man (OMIM), the Molecular Modeling Database (MMDB) and the Conserved Domain Database (CDD). Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of the resources can be accessed through the NCBI home page at: http://www.ncbi.nlm.nih.gov. PMID:11125038
Database resources of the National Center for Biotechnology Information.
Sayers, Eric W; Barrett, Tanya; Benson, Dennis A; Bolton, Evan; Bryant, Stephen H; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M; Dicuccio, Michael; Federhen, Scott; Feolo, Michael; Fingerman, Ian M; Geer, Lewis Y; Helmberg, Wolfgang; Kapustin, Yuri; Krasnov, Sergey; Landsman, David; Lipman, David J; Lu, Zhiyong; Madden, Thomas L; Madej, Tom; Maglott, Donna R; Marchler-Bauer, Aron; Miller, Vadim; Karsch-Mizrachi, Ilene; Ostell, James; Panchenko, Anna; Phan, Lon; Pruitt, Kim D; Schuler, Gregory D; Sequeira, Edwin; Sherry, Stephen T; Shumway, Martin; Sirotkin, Karl; Slotta, Douglas; Souvorov, Alexandre; Starchenko, Grigory; Tatusova, Tatiana A; Wagner, Lukas; Wang, Yanli; Wilbur, W John; Yaschenko, Eugene; Ye, Jian
2012-01-01
In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI Website. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central (PMC), Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Primer-BLAST, COBALT, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, dbVar, Epigenomics, Genome and related tools, the Map Viewer, Model Maker, Evidence Viewer, Trace Archive, Sequence Read Archive, BioProject, BioSample, Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus (GEO), Probe, Online Mendelian Inheritance in Animals (OMIA), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), Biosystems, Protein Clusters and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.
Database resources of the National Center for Biotechnology Information
Acland, Abigail; Agarwala, Richa; Barrett, Tanya; Beck, Jeff; Benson, Dennis A.; Bollin, Colleen; Bolton, Evan; Bryant, Stephen H.; Canese, Kathi; Church, Deanna M.; Clark, Karen; DiCuccio, Michael; Dondoshansky, Ilya; Federhen, Scott; Feolo, Michael; Geer, Lewis Y.; Gorelenkov, Viatcheslav; Hoeppner, Marilu; Johnson, Mark; Kelly, Christopher; Khotomlianski, Viatcheslav; Kimchi, Avi; Kimelman, Michael; Kitts, Paul; Krasnov, Sergey; Kuznetsov, Anatoliy; Landsman, David; Lipman, David J.; Lu, Zhiyong; Madden, Thomas L.; Madej, Tom; Maglott, Donna R.; Marchler-Bauer, Aron; Karsch-Mizrachi, Ilene; Murphy, Terence; Ostell, James; O'Sullivan, Christopher; Panchenko, Anna; Phan, Lon; Pruitt, Don Preussm Kim D.; Rubinstein, Wendy; Sayers, Eric W.; Schneider, Valerie; Schuler, Gregory D.; Sequeira, Edwin; Sherry, Stephen T.; Shumway, Martin; Sirotkin, Karl; Siyan, Karanjit; Slotta, Douglas; Soboleva, Alexandra; Soussov, Vladimir; Starchenko, Grigory; Tatusova, Tatiana A.; Trawick, Bart W.; Vakatov, Denis; Wang, Yanli; Ward, Minghong; John Wilbur, W.; Yaschenko, Eugene; Zbicz, Kerry
2014-01-01
In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI, http://www.ncbi.nlm.nih.gov) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI Web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central, PubReader, Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link, Primer-BLAST, COBALT, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, dbVar, Epigenomics, the Genetic Testing Registry, Genome and related tools, the Map Viewer, Trace Archive, Sequence Read Archive, BioProject, BioSample, ClinVar, MedGen, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus, Probe, Online Mendelian Inheritance in Animals, the Molecular Modeling Database, the Conserved Domain Database, the Conserved Domain Architecture Retrieval Tool, Biosystems, Protein Clusters and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All these resources can be accessed through the NCBI home page. PMID:24259429
Database resources of the National Center for Biotechnology
Wheeler, David L.; Church, Deanna M.; Federhen, Scott; Lash, Alex E.; Madden, Thomas L.; Pontius, Joan U.; Schuler, Gregory D.; Schriml, Lynn M.; Sequeira, Edwin; Tatusova, Tatiana A.; Wagner, Lukas
2003-01-01
In addition to maintaining the GenBank(R) nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides data analysis and retrieval resources for the data in GenBank and other biological data made available through NCBI's Web site. NCBI resources include Entrez, PubMed, PubMed Central (PMC), LocusLink, the NCBITaxonomy Browser, BLAST, BLAST Link (BLink), Electronic PCR (e-PCR), Open Reading Frame (ORF) Finder, References Sequence (RefSeq), UniGene, HomoloGene, ProtEST, Database of Single Nucleotide Polymorphisms (dbSNP), Human/Mouse Homology Map, Cancer Chromosome Aberration Project (CCAP), Entrez Genomes and related tools, the Map Viewer, Model Maker (MM), Evidence Viewer (EV), Clusters of Orthologous Groups (COGs) database, Retroviral Genotyping Tools, SAGEmap, Gene Expression Omnibus (GEO), Online Mendelian Inheritance in Man (OMIM), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), and the Conserved Domain Architecture Retrieval Tool (CDART). Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of the resources can be accessed through the NCBI home page at: http://www.ncbi.nlm.nih.gov. PMID:12519941
Database resources of the National Center for Biotechnology Information
Sayers, Eric W.; Barrett, Tanya; Benson, Dennis A.; Bolton, Evan; Bryant, Stephen H.; Canese, Kathi; Chetvernin, Vyacheslav; Church, Deanna M.; DiCuccio, Michael; Federhen, Scott; Feolo, Michael; Fingerman, Ian M.; Geer, Lewis Y.; Helmberg, Wolfgang; Kapustin, Yuri; Krasnov, Sergey; Landsman, David; Lipman, David J.; Lu, Zhiyong; Madden, Thomas L.; Madej, Tom; Maglott, Donna R.; Marchler-Bauer, Aron; Miller, Vadim; Karsch-Mizrachi, Ilene; Ostell, James; Panchenko, Anna; Phan, Lon; Pruitt, Kim D.; Schuler, Gregory D.; Sequeira, Edwin; Sherry, Stephen T.; Shumway, Martin; Sirotkin, Karl; Slotta, Douglas; Souvorov, Alexandre; Starchenko, Grigory; Tatusova, Tatiana A.; Wagner, Lukas; Wang, Yanli; Wilbur, W. John; Yaschenko, Eugene; Ye, Jian
2012-01-01
In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI Website. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central (PMC), Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Primer-BLAST, COBALT, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, dbVar, Epigenomics, Genome and related tools, the Map Viewer, Model Maker, Evidence Viewer, Trace Archive, Sequence Read Archive, BioProject, BioSample, Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus (GEO), Probe, Online Mendelian Inheritance in Animals (OMIA), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), Biosystems, Protein Clusters and the PubChem suite of small molecule databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov. PMID:22140104
Database resources of the National Center for Biotechnology Information
2013-01-01
In addition to maintaining the GenBank® nucleic acid sequence database, the National Center for Biotechnology Information (NCBI, http://www.ncbi.nlm.nih.gov) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central, Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Primer-BLAST, COBALT, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, dbVar, Epigenomics, the Genetic Testing Registry, Genome and related tools, the Map Viewer, Model Maker, Evidence Viewer, Trace Archive, Sequence Read Archive, BioProject, BioSample, Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus, Probe, Online Mendelian Inheritance in Animals, the Molecular Modeling Database, the Conserved Domain Database, the Conserved Domain Architecture Retrieval Tool, Biosystems, Protein Clusters and the PubChem suite of small molecule databases. Augmenting many of the web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page. PMID:23193264
WPBMB Entrez: An interface to NCBI Entrez for Wordpress.
Gohara, David W
2018-03-01
Research-oriented websites are an important means for the timely communication of information. These websites fall under a number of categories including: research laboratories, training grant and program projects, and online service portals. Invariably there is content on a site, such as publication listings, that require frequent updating. A number of content management systems exist to aid in the task of developing and managing a website, each with their strengths and weaknesses. One popular choice is Wordpress, a free, open source and actively developed application for the creation of web content. During a recent site redesign for our department, the need arose to ensure publications were up to date for each of the research labs and department as a whole. Several plugins for Wordpress offer this type of functionality, but in many cases the plugins are either no longer maintained, are missing features that would require the use of several, possibly incompatible, plugins or lack features for layout on a webpage. WPBMB Entrez was developed to address these needs. WPBMB Entrez utilizes a subset of NCBI Entrez and RCSB databases to maintain up to date records of publications, and publication related information on Wordpress-based websites. The core functionality uses the same search query syntax as on the NCBI Entrez site, including advanced query syntaxes. The plugin is extensible allowing for rapid development and addition of new data sources as the need arises. WPBMB Entrez was designed to be easy to use, yet flexible enough to address more complex usage scenarios. Features of the plugin include: an easy to use interface, design customization, multiple templates for displaying publication results, a caching mechanism to reduce page load times, supports multiple distinct queries and retrieval modes, and the ability to aggregate multiple queries into unified lists. Additionally, developer documentation is provided to aid in customization of the plugin. WPBMB Entrez is available at no cost, is open source and works with all recent versions of Wordpress. Copyright © 2017 Elsevier B.V. All rights reserved.
Worley, K C; Wiese, B A; Smith, R F
1995-09-01
BEAUTY (BLAST enhanced alignment utility) is an enhanced version of the NCBI's BLAST data base search tool that facilitates identification of the functions of matched sequences. We have created new data bases of conserved regions and functional domains for protein sequences in NCBI's Entrez data base, and BEAUTY allows this information to be incorporated directly into BLAST search results. A Conserved Regions Data Base, containing the locations of conserved regions within Entrez protein sequences, was constructed by (1) clustering the entire data base into families, (2) aligning each family using our PIMA multiple sequence alignment program, and (3) scanning the multiple alignments to locate the conserved regions within each aligned sequence. A separate Annotated Domains Data Base was constructed by extracting the locations of all annotated domains and sites from sequences represented in the Entrez, PROSITE, BLOCKS, and PRINTS data bases. BEAUTY performs a BLAST search of those Entrez sequences with conserved regions and/or annotated domains. BEAUTY then uses the information from the Conserved Regions and Annotated Domains data bases to generate, for each matched sequence, a schematic display that allows one to directly compare the relative locations of (1) the conserved regions, (2) annotated domains and sites, and (3) the locally aligned regions matched in the BLAST search. In addition, BEAUTY search results include World-Wide Web hypertext links to a number of external data bases that provide a variety of additional types of information on the function of matched sequences. This convenient integration of protein families, conserved regions, annotated domains, alignment displays, and World-Wide Web resources greatly enhances the biological informativeness of sequence similarity searches. BEAUTY searches can be performed remotely on our system using the "BCM Search Launcher" World-Wide Web pages (URL is < http:/ /gc.bcm.tmc.edu:8088/ search-launcher/launcher.html > ).
Sahoo, Satya S.; Bodenreider, Olivier; Rutter, Joni L.; Skinner, Karen J.; Sheth, Amit P.
2008-01-01
Objectives This paper illustrates how Semantic Web technologies (especially RDF, OWL, and SPARQL) can support information integration and make it easy to create semantic mashups (semantically integrated resources). In the context of understanding the genetic basis of nicotine dependence, we integrate gene and pathway information and show how three complex biological queries can be answered by the integrated knowledge base. Methods We use an ontology-driven approach to integrate two gene resources (Entrez Gene and HomoloGene) and three pathway resources (KEGG, Reactome and BioCyc), for five organisms, including humans. We created the Entrez Knowledge Model (EKoM), an information model in OWL for the gene resources, and integrated it with the extant BioPAX ontology designed for pathway resources. The integrated schema is populated with data from the pathway resources, publicly available in BioPAX-compatible format, and gene resources for which a population procedure was created. The SPARQL query language is used to formulate queries over the integrated knowledge base to answer the three biological queries. Results Simple SPARQL queries could easily identify hub genes, i.e., those genes whose gene products participate in many pathways or interact with many other gene products. The identification of the genes expressed in the brain turned out to be more difficult, due to the lack of a common identification scheme for proteins. Conclusion Semantic Web technologies provide a valid framework for information integration in the life sciences. Ontology-driven integration represents a flexible, sustainable and extensible solution to the integration of large volumes of information. Additional resources, which enable the creation of mappings between information sources, are required to compensate for heterogeneity across namespaces. Resource page http://knoesis.wright.edu/research/lifesci/integration/structured_data/JBI-2008/ PMID:18395495
Sahoo, Satya S; Bodenreider, Olivier; Rutter, Joni L; Skinner, Karen J; Sheth, Amit P
2008-10-01
This paper illustrates how Semantic Web technologies (especially RDF, OWL, and SPARQL) can support information integration and make it easy to create semantic mashups (semantically integrated resources). In the context of understanding the genetic basis of nicotine dependence, we integrate gene and pathway information and show how three complex biological queries can be answered by the integrated knowledge base. We use an ontology-driven approach to integrate two gene resources (Entrez Gene and HomoloGene) and three pathway resources (KEGG, Reactome and BioCyc), for five organisms, including humans. We created the Entrez Knowledge Model (EKoM), an information model in OWL for the gene resources, and integrated it with the extant BioPAX ontology designed for pathway resources. The integrated schema is populated with data from the pathway resources, publicly available in BioPAX-compatible format, and gene resources for which a population procedure was created. The SPARQL query language is used to formulate queries over the integrated knowledge base to answer the three biological queries. Simple SPARQL queries could easily identify hub genes, i.e., those genes whose gene products participate in many pathways or interact with many other gene products. The identification of the genes expressed in the brain turned out to be more difficult, due to the lack of a common identification scheme for proteins. Semantic Web technologies provide a valid framework for information integration in the life sciences. Ontology-driven integration represents a flexible, sustainable and extensible solution to the integration of large volumes of information. Additional resources, which enable the creation of mappings between information sources, are required to compensate for heterogeneity across namespaces. RESOURCE PAGE: http://knoesis.wright.edu/research/lifesci/integration/structured_data/JBI-2008/
WWW Entrez: A Hypertext Retrieval Tool for Molecular Biology.
ERIC Educational Resources Information Center
Epstein, Jonathan A.; Kans, Jonathan A.; Schuler, Gregory D.
This article describes the World Wide Web (WWW) Entrez server which is based upon the National Center for Biotechnology Information's (NCBI) Entrez retrieval database and software. Entrez is a molecular sequence retrieval system that contains an integrated view of portions of Medline and all publicly available nucleotide and protein databases,…
Gene: a gene-centered information resource at NCBI.
Brown, Garth R; Hem, Vichet; Katz, Kenneth S; Ovetsky, Michael; Wallin, Craig; Ermolaeva, Olga; Tolstoy, Igor; Tatusova, Tatiana; Pruitt, Kim D; Maglott, Donna R; Murphy, Terence D
2015-01-01
The National Center for Biotechnology Information's (NCBI) Gene database (www.ncbi.nlm.nih.gov/gene) integrates gene-specific information from multiple data sources. NCBI Reference Sequence (RefSeq) genomes for viruses, prokaryotes and eukaryotes are the primary foundation for Gene records in that they form the critical association between sequence and a tracked gene upon which additional functional and descriptive content is anchored. Additional content is integrated based on the genomic location and RefSeq transcript and protein sequence data. The content of a Gene record represents the integration of curation and automated processing from RefSeq, collaborating model organism databases, consortia such as Gene Ontology, and other databases within NCBI. Records in Gene are assigned unique, tracked integers as identifiers. The content (citations, nomenclature, genomic location, gene products and their attributes, phenotypes, sequences, interactions, variation details, maps, expression, homologs, protein domains and external databases) is available via interactive browsing through NCBI's Entrez system, via NCBI's Entrez programming utilities (E-Utilities and Entrez Direct) and for bulk transfer by FTP. Published by Oxford University Press on behalf of Nucleic Acids Research 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.
EST Express: PHP/MySQL based automated annotation of ESTs from expression libraries
Smith, Robin P; Buchser, William J; Lemmon, Marcus B; Pardinas, Jose R; Bixby, John L; Lemmon, Vance P
2008-01-01
Background Several biological techniques result in the acquisition of functional sets of cDNAs that must be sequenced and analyzed. The emergence of redundant databases such as UniGene and centralized annotation engines such as Entrez Gene has allowed the development of software that can analyze a great number of sequences in a matter of seconds. Results We have developed "EST Express", a suite of analytical tools that identify and annotate ESTs originating from specific mRNA populations. The software consists of a user-friendly GUI powered by PHP and MySQL that allows for online collaboration between researchers and continuity with UniGene, Entrez Gene and RefSeq. Two key features of the software include a novel, simplified Entrez Gene parser and tools to manage cDNA library sequencing projects. We have tested the software on a large data set (2,016 samples) produced by subtractive hybridization. Conclusion EST Express is an open-source, cross-platform web server application that imports sequences from cDNA libraries, such as those generated through subtractive hybridization or yeast two-hybrid screens. It then provides several layers of annotation based on Entrez Gene and RefSeq to allow the user to highlight useful genes and manage cDNA library projects. PMID:18402700
EST Express: PHP/MySQL based automated annotation of ESTs from expression libraries.
Smith, Robin P; Buchser, William J; Lemmon, Marcus B; Pardinas, Jose R; Bixby, John L; Lemmon, Vance P
2008-04-10
Several biological techniques result in the acquisition of functional sets of cDNAs that must be sequenced and analyzed. The emergence of redundant databases such as UniGene and centralized annotation engines such as Entrez Gene has allowed the development of software that can analyze a great number of sequences in a matter of seconds. We have developed "EST Express", a suite of analytical tools that identify and annotate ESTs originating from specific mRNA populations. The software consists of a user-friendly GUI powered by PHP and MySQL that allows for online collaboration between researchers and continuity with UniGene, Entrez Gene and RefSeq. Two key features of the software include a novel, simplified Entrez Gene parser and tools to manage cDNA library sequencing projects. We have tested the software on a large data set (2,016 samples) produced by subtractive hybridization. EST Express is an open-source, cross-platform web server application that imports sequences from cDNA libraries, such as those generated through subtractive hybridization or yeast two-hybrid screens. It then provides several layers of annotation based on Entrez Gene and RefSeq to allow the user to highlight useful genes and manage cDNA library projects.
PubChem promiscuity: a web resource for gathering compound promiscuity data from PubChem.
Canny, Stephanie A; Cruz, Yasel; Southern, Mark R; Griffin, Patrick R
2012-01-01
Promiscuity counts allow for a better understanding of a compound's assay activity profile and drug potential. Although PubChem contains a vast amount of compound and assay data, it currently does not have a convenient or efficient method to obtain in-depth promiscuity counts for compounds. PubChem promiscuity fills this gap. It is a Java servlet that uses NCBI Entrez (eUtils) web services to interact with PubChem and provide promiscuity counts in a variety of categories along with compound descriptors, including PAINS-based functional group detection. http://chemutils.florida.scripps.edu/pcpromiscuity southern@scripps.edu
PubChem promiscuity: a web resource for gathering compound promiscuity data from PubChem
Canny, Stephanie A.; Cruz, Yasel; Southern, Mark R.; Griffin, Patrick R.
2012-01-01
Summary: Promiscuity counts allow for a better understanding of a compound's assay activity profile and drug potential. Although PubChem contains a vast amount of compound and assay data, it currently does not have a convenient or efficient method to obtain in-depth promiscuity counts for compounds. PubChem promiscuity fills this gap. It is a Java servlet that uses NCBI Entrez (eUtils) web services to interact with PubChem and provide promiscuity counts in a variety of categories along with compound descriptors, including PAINS-based functional group detection. Availability: http://chemutils.florida.scripps.edu/pcpromiscuity Contact: southern@scripps.edu PMID:22084255
Geer, Lewis Y; Marchler-Bauer, Aron; Geer, Renata C; Han, Lianyi; He, Jane; He, Siqian; Liu, Chunlei; Shi, Wenyao; Bryant, Stephen H
2010-01-01
The NCBI BioSystems database, found at http://www.ncbi.nlm.nih.gov/biosystems/, centralizes and cross-links existing biological systems databases, increasing their utility and target audience by integrating their pathways and systems into NCBI resources. This integration allows users of NCBI's Entrez databases to quickly categorize proteins, genes and small molecules by metabolic pathway, disease state or other BioSystem type, without requiring time-consuming inference of biological relationships from the literature or multiple experimental datasets.
Geer, Lewis Y.; Marchler-Bauer, Aron; Geer, Renata C.; Han, Lianyi; He, Jane; He, Siqian; Liu, Chunlei; Shi, Wenyao; Bryant, Stephen H.
2010-01-01
The NCBI BioSystems database, found at http://www.ncbi.nlm.nih.gov/biosystems/, centralizes and cross-links existing biological systems databases, increasing their utility and target audience by integrating their pathways and systems into NCBI resources. This integration allows users of NCBI’s Entrez databases to quickly categorize proteins, genes and small molecules by metabolic pathway, disease state or other BioSystem type, without requiring time-consuming inference of biological relationships from the literature or multiple experimental datasets. PMID:19854944
Clone DB: an integrated NCBI resource for clone-associated data
Schneider, Valerie A.; Chen, Hsiu-Chuan; Clausen, Cliff; Meric, Peter A.; Zhou, Zhigang; Bouk, Nathan; Husain, Nora; Maglott, Donna R.; Church, Deanna M.
2013-01-01
The National Center for Biotechnology Information (NCBI) Clone DB (http://www.ncbi.nlm.nih.gov/clone/) is an integrated resource providing information about and facilitating access to clones, which serve as valuable research reagents in many fields, including genome sequencing and variation analysis. Clone DB represents an expansion and replacement of the former NCBI Clone Registry and has records for genomic and cell-based libraries and clones representing more than 100 different eukaryotic taxa. Records provide details of library construction, associated sequences, map positions and information about resource distribution. Clone DB is indexed in the NCBI Entrez system and can be queried by fields that include organism, clone name, gene name and sequence identifier. Whenever possible, genomic clones are mapped to reference assemblies and their map positions provided in clone records. Clones mapping to specific genomic regions can also be searched for using the NCBI Clone Finder tool, which accepts queries based on sequence coordinates or features such as gene or transcript names. Clone DB makes reports of library, clone and placement data on its FTP site available for download. With Clone DB, users now have available to them a centralized resource that provides them with the tools they will need to make use of these important research reagents. PMID:23193260
Database resources of the National Center for Biotechnology Information
2015-01-01
The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. Additional NCBI resources focus on literature (Bookshelf, PubMed Central (PMC) and PubReader); medical genetics (ClinVar, dbMHC, the Genetic Testing Registry, HIV-1/Human Protein Interaction Database and MedGen); genes and genomics (BioProject, BioSample, dbSNP, dbVar, Epigenomics, Gene, Gene Expression Omnibus (GEO), Genome, HomoloGene, the Map Viewer, Nucleotide, PopSet, Probe, RefSeq, Sequence Read Archive, the Taxonomy Browser, Trace Archive and UniGene); and proteins and chemicals (Biosystems, COBALT, the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), the Molecular Modeling Database (MMDB), Protein Clusters, Protein and the PubChem suite of small molecule databases). The Entrez system provides search and retrieval operations for many of these databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page at http://www.ncbi.nlm.nih.gov. PMID:25398906
Database resources of the National Center for Biotechnology Information
2016-01-01
The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. Additional NCBI resources focus on literature (PubMed Central (PMC), Bookshelf and PubReader), health (ClinVar, dbGaP, dbMHC, the Genetic Testing Registry, HIV-1/Human Protein Interaction Database and MedGen), genomes (BioProject, Assembly, Genome, BioSample, dbSNP, dbVar, Epigenomics, the Map Viewer, Nucleotide, Probe, RefSeq, Sequence Read Archive, the Taxonomy Browser and the Trace Archive), genes (Gene, Gene Expression Omnibus (GEO), HomoloGene, PopSet and UniGene), proteins (Protein, the Conserved Domain Database (CDD), COBALT, Conserved Domain Architecture Retrieval Tool (CDART), the Molecular Modeling Database (MMDB) and Protein Clusters) and chemicals (Biosystems and the PubChem suite of small molecule databases). The Entrez system provides search and retrieval operations for most of these databases. Augmenting many of the web applications are custom implementations of the BLAST program optimized to search specialized datasets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov. PMID:26615191
Teaching bioinformatics and neuroinformatics by using free web-based tools.
Grisham, William; Schottler, Natalie A; Valli-Marill, Joanne; Beck, Lisa; Beatty, Jackson
2010-01-01
This completely computer-based module's purpose is to introduce students to bioinformatics resources. We present an easy-to-adopt module that weaves together several important bioinformatic tools so students can grasp how these tools are used in answering research questions. Students integrate information gathered from websites dealing with anatomy (Mouse Brain Library), quantitative trait locus analysis (WebQTL from GeneNetwork), bioinformatics and gene expression analyses (University of California, Santa Cruz Genome Browser, National Center for Biotechnology Information's Entrez Gene, and the Allen Brain Atlas), and information resources (PubMed). Instructors can use these various websites in concert to teach genetics from the phenotypic level to the molecular level, aspects of neuroanatomy and histology, statistics, quantitative trait locus analysis, and molecular biology (including in situ hybridization and microarray analysis), and to introduce bioinformatic resources. Students use these resources to discover 1) the region(s) of chromosome(s) influencing the phenotypic trait, 2) a list of candidate genes-narrowed by expression data, 3) the in situ pattern of a given gene in the region of interest, 4) the nucleotide sequence of the candidate gene, and 5) articles describing the gene. Teaching materials such as a detailed student/instructor's manual, PowerPoints, sample exams, and links to free Web resources can be found at http://mdcune.psych.ucla.edu/modules/bioinformatics.
Fungal genome resources at NCBI.
Robbertse, B; Tatusova, T
2011-09-01
The National Center for Biotechnology Information (NCBI) is well known for the nucleotide sequence archive, GenBank and sequence analysis tool BLAST. However, NCBI integrates many types of biomolecular data from variety of sources and makes it available to the scientific community as interactive web resources as well as organized releases of bulk data. These tools are available to explore and compare fungal genomes. Searching all databases with Fungi [organism] at http://www.ncbi.nlm.nih.gov/ is the quickest way to find resources of interest with fungal entries. Some tools though are resources specific and can be indirectly accessed from a particular database in the Entrez system. These include graphical viewers and comparative analysis tools such as TaxPlot, TaxMap and UniGene DDD (found via UniGene Homepage). Gene and BioProject pages also serve as portals to external data such as community annotation websites, BioGrid and UniProt. There are many different ways of accessing genomic data at NCBI. Depending on the focus and goal of research projects or the level of interest, a user would select a particular route for accessing genomic databases and resources. This review article describes methods of accessing fungal genome data and provides examples that illustrate the use of analysis tools.
The NIF DISCO Framework: facilitating automated integration of neuroscience content on the web.
Marenco, Luis; Wang, Rixin; Shepherd, Gordon M; Miller, Perry L
2010-06-01
This paper describes the capabilities of DISCO, an extensible approach that supports integrative Web-based information dissemination. DISCO is a component of the Neuroscience Information Framework (NIF), an NIH Neuroscience Blueprint initiative that facilitates integrated access to diverse neuroscience resources via the Internet. DISCO facilitates the automated maintenance of several distinct capabilities using a collection of files 1) that are maintained locally by the developers of participating neuroscience resources and 2) that are "harvested" on a regular basis by a central DISCO server. This approach allows central NIF capabilities to be updated as each resource's content changes over time. DISCO currently supports the following capabilities: 1) resource descriptions, 2) "LinkOut" to a resource's data items from NCBI Entrez resources such as PubMed, 3) Web-based interoperation with a resource, 4) sharing a resource's lexicon and ontology, 5) sharing a resource's database schema, and 6) participation by the resource in neuroscience-related RSS news dissemination. The developers of a resource are free to choose which DISCO capabilities their resource will participate in. Although DISCO is used by NIF to facilitate neuroscience data integration, its capabilities have general applicability to other areas of research.
Genome-wide association studies in Alzheimer disease.
Waring, Stephen C; Rosenberg, Roger N
2008-03-01
The genetics of Alzheimer disease (AD) to date support an age-dependent dichotomous model whereby earlier age of disease onset (< 60 years) is explained by 3 fully penetrant genes (APP [NCBI Entrez gene 351], PSEN1 [NCBI Entrez gene 5663], and PSEN2 [NCBI Entrez gene 5664]), whereas later age of disease onset (> or = 65 years) representing most cases of AD has yet to be explained by a purely genetic model. The APOE gene (NCBI Entrez gene 348) is the strongest genetic risk factor for later onset, although it is neither sufficient nor necessary to explain all occurrences of disease. Numerous putative genetic risk alleles and genetic variants have been reported. Although all have relevance to biological mechanisms that may be associated with AD pathogenesis, they await replication in large representative populations. Genome-wide association studies have emerged as an increasingly effective tool for identifying genetic contributions to complex diseases and represent the next frontier for furthering our understanding of the underlying etiologic, biological, and pathologic mechanisms associated with chronic complex disorders. There have already been success stories for diseases such as macular degeneration and diabetes mellitus. Whether this will hold true for a genetically complex and heterogeneous disease such as AD is not known, although early reports are encouraging. This review considers recent publications from studies that have successfully applied genome-wide association methods to investigations of AD by taking advantage of the currently available high-throughput arrays, bioinformatics, and software advances. The inherent strengths, limitations, and challenges associated with study design issues in the context of AD are presented herein.
Database resources of the National Center for Biotechnology Information.
2016-01-04
The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank(®) nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. Additional NCBI resources focus on literature (PubMed Central (PMC), Bookshelf and PubReader), health (ClinVar, dbGaP, dbMHC, the Genetic Testing Registry, HIV-1/Human Protein Interaction Database and MedGen), genomes (BioProject, Assembly, Genome, BioSample, dbSNP, dbVar, Epigenomics, the Map Viewer, Nucleotide, Probe, RefSeq, Sequence Read Archive, the Taxonomy Browser and the Trace Archive), genes (Gene, Gene Expression Omnibus (GEO), HomoloGene, PopSet and UniGene), proteins (Protein, the Conserved Domain Database (CDD), COBALT, Conserved Domain Architecture Retrieval Tool (CDART), the Molecular Modeling Database (MMDB) and Protein Clusters) and chemicals (Biosystems and the PubChem suite of small molecule databases). The Entrez system provides search and retrieval operations for most of these databases. Augmenting many of the web applications are custom implementations of the BLAST program optimized to search specialized datasets. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov. Published by Oxford University Press on behalf of Nucleic Acids Research 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.
Database resources of the National Center for Biotechnology Information.
2015-01-01
The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank(®) nucleic acid sequence database and the PubMed database of citations and abstracts for published life science journals. Additional NCBI resources focus on literature (Bookshelf, PubMed Central (PMC) and PubReader); medical genetics (ClinVar, dbMHC, the Genetic Testing Registry, HIV-1/Human Protein Interaction Database and MedGen); genes and genomics (BioProject, BioSample, dbSNP, dbVar, Epigenomics, Gene, Gene Expression Omnibus (GEO), Genome, HomoloGene, the Map Viewer, Nucleotide, PopSet, Probe, RefSeq, Sequence Read Archive, the Taxonomy Browser, Trace Archive and UniGene); and proteins and chemicals (Biosystems, COBALT, the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART), the Molecular Modeling Database (MMDB), Protein Clusters, Protein and the PubChem suite of small molecule databases). The Entrez system provides search and retrieval operations for many of these databases. Augmenting many of the Web applications are custom implementations of the BLAST program optimized to search specialized data sets. All of these resources can be accessed through the NCBI home page at http://www.ncbi.nlm.nih.gov. Published by Oxford University Press on behalf of Nucleic Acids Research 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.
The NIF DISCO Framework: Facilitating Automated Integration of Neuroscience Content on the Web
Marenco, Luis; Wang, Rixin; Shepherd, Gordon M.; Miller, Perry L.
2013-01-01
This paper describes the capabilities of DISCO, an extensible approach that supports integrative Web-based information dissemination. DISCO is a component of the Neuroscience Information Framework (NIF), an NIH Neuroscience Blueprint initiative that facilitates integrated access to diverse neuroscience resources via the Internet. DISCO facilitates the automated maintenance of several distinct capabilities using a collection of files 1) that are maintained locally by the developers of participating neuroscience resources and 2) that are “harvested” on a regular basis by a central DISCO server. This approach allows central NIF capabilities to be updated as each resource’s content changes over time. DISCO currently supports the following capabilities: 1) resource descriptions, 2) “LinkOut” to a resource’s data items from NCBI Entrez resources such as PubMed, 3) Web-based interoperation with a resource, 4) sharing a resource’s lexicon and ontology, 5) sharing a resource’s database schema, and 6) participation by the resource in neuroscience-related RSS news dissemination. The developers of a resource are free to choose which DISCO capabilities their resource will participate in. Although DISCO is used by NIF to facilitate neuroscience data integration, its capabilities have general applicability to other areas of research. PMID:20387131
DGEM--a microarray gene expression database for primary human disease tissues.
Xia, Yuni; Campen, Andrew; Rigsby, Dan; Guo, Ying; Feng, Xingdong; Su, Eric W; Palakal, Mathew; Li, Shuyu
2007-01-01
Gene expression patterns can reflect gene regulations in human tissues under normal or pathologic conditions. Gene expression profiling data from studies of primary human disease samples are particularly valuable since these studies often span many years in order to collect patient clinical information and achieve a large sample size. Disease-to-Gene Expression Mapper (DGEM) provides a beneficial community resource to access and analyze these data; it currently includes Affymetrix oligonucleotide array datasets for more than 40 human diseases and 1400 samples. The data are normalized to the same scale and stored in a relational database. A statistical-analysis pipeline was implemented to identify genes abnormally expressed in disease tissues or genes whose expressions are associated with clinical parameters such as cancer patient survival. Data-mining results can be queried through a web-based interface at http://dgem.dhcp.iupui.edu/. The query tool enables dynamic generation of graphs and tables that are further linked to major gene and pathway resources that connect the data to relevant biology, including Entrez Gene and Kyoto Encyclopedia of Genes and Genomes (KEGG). In summary, DGEM provides scientists and physicians a valuable tool to study disease mechanisms, to discover potential disease biomarkers for diagnosis and prognosis, and to identify novel gene targets for drug discovery. The source code is freely available for non-profit use, on request to the authors.
Preliminary Comparison of Three Search Engines for Point of Care Access to MEDLINE® Citations
Hauser, Susan E.; Demner-Fushman, Dina; Ford, Glenn M.; Jacobs, Joshua L.; Thoma, George
2006-01-01
Medical resident physicians used MD on Tap in real time to search for MEDLINE citations relevant to clinical questions using three search engines: Essie, Entrez and Google™, in order of performance. PMID:17238564
Ochsner, Scott A; Watkins, Christopher M; LaGrone, Benjamin S; Steffen, David L; McKenna, Neil J
2010-10-01
Nuclear receptors (NRs) are ligand-regulated transcription factors that recruit coregulators and other transcription factors to gene promoters to effect regulation of tissue-specific transcriptomes. The prodigious rate at which the NR signaling field has generated high content gene expression and, more recently, genome-wide location analysis datasets has not been matched by a committed effort to archiving this information for routine access by bench and clinical scientists. As a first step towards this goal, we searched the MEDLINE database for studies, which referenced either expression microarray and/or genome-wide location analysis datasets in which a NR or NR ligand was an experimental variable. A total of 1122 studies encompassing 325 unique organs, tissues, primary cells, and cell lines, 35 NRs, and 91 NR ligands were retrieved and annotated. The data were incorporated into a new section of the Nuclear Receptor Signaling Atlas Molecule Pages, Transcriptomics and Cistromics, for which we designed an intuitive, freely accessible user interface to browse the studies. Each study links to an abstract, the MEDLINE record, and, where available, Gene Expression Omnibus and ArrayExpress records. The resource will be updated on a regular basis to provide a current and comprehensive entrez into the sum of transcriptomic and cistromic research in this field.
2013-01-01
Background Due to the growing number of biomedical entries in data repositories of the National Center for Biotechnology Information (NCBI), it is difficult to collect, manage and process all of these entries in one place by third-party software developers without significant investment in hardware and software infrastructure, its maintenance and administration. Web services allow development of software applications that integrate in one place the functionality and processing logic of distributed software components, without integrating the components themselves and without integrating the resources to which they have access. This is achieved by appropriate orchestration or choreography of available Web services and their shared functions. After the successful application of Web services in the business sector, this technology can now be used to build composite software tools that are oriented towards biomedical data processing. Results We have developed a new tool for efficient and dynamic data exploration in GenBank and other NCBI databases. A dedicated search GenBank system makes use of NCBI Web services and a package of Entrez Programming Utilities (eUtils) in order to provide extended searching capabilities in NCBI data repositories. In search GenBank users can use one of the three exploration paths: simple data searching based on the specified user’s query, advanced data searching based on the specified user’s query, and advanced data exploration with the use of macros. search GenBank orchestrates calls of particular tools available through the NCBI Web service providing requested functionality, while users interactively browse selected records in search GenBank and traverse between NCBI databases using available links. On the other hand, by building macros in the advanced data exploration mode, users create choreographies of eUtils calls, which can lead to the automatic discovery of related data in the specified databases. Conclusions search GenBank extends standard capabilities of the NCBI Entrez search engine in querying biomedical databases. The possibility of creating and saving macros in the search GenBank is a unique feature and has a great potential. The potential will further grow in the future with the increasing density of networks of relationships between data stored in particular databases. search GenBank is available for public use at http://sgb.biotools.pl/. PMID:23452691
Mrozek, Dariusz; Małysiak-Mrozek, Bożena; Siążnik, Artur
2013-03-01
Due to the growing number of biomedical entries in data repositories of the National Center for Biotechnology Information (NCBI), it is difficult to collect, manage and process all of these entries in one place by third-party software developers without significant investment in hardware and software infrastructure, its maintenance and administration. Web services allow development of software applications that integrate in one place the functionality and processing logic of distributed software components, without integrating the components themselves and without integrating the resources to which they have access. This is achieved by appropriate orchestration or choreography of available Web services and their shared functions. After the successful application of Web services in the business sector, this technology can now be used to build composite software tools that are oriented towards biomedical data processing. We have developed a new tool for efficient and dynamic data exploration in GenBank and other NCBI databases. A dedicated search GenBank system makes use of NCBI Web services and a package of Entrez Programming Utilities (eUtils) in order to provide extended searching capabilities in NCBI data repositories. In search GenBank users can use one of the three exploration paths: simple data searching based on the specified user's query, advanced data searching based on the specified user's query, and advanced data exploration with the use of macros. search GenBank orchestrates calls of particular tools available through the NCBI Web service providing requested functionality, while users interactively browse selected records in search GenBank and traverse between NCBI databases using available links. On the other hand, by building macros in the advanced data exploration mode, users create choreographies of eUtils calls, which can lead to the automatic discovery of related data in the specified databases. search GenBank extends standard capabilities of the NCBI Entrez search engine in querying biomedical databases. The possibility of creating and saving macros in the search GenBank is a unique feature and has a great potential. The potential will further grow in the future with the increasing density of networks of relationships between data stored in particular databases. search GenBank is available for public use at http://sgb.biotools.pl/.
Samwald, Matthias; Lim, Ernest; Masiar, Peter; Marenco, Luis; Chen, Huajun; Morse, Thomas; Mutalik, Pradeep; Shepherd, Gordon; Miller, Perry; Cheung, Kei-Hoi
2009-01-01
The amount of biomedical data available in Semantic Web formats has been rapidly growing in recent years. While these formats are machine-friendly, user-friendly web interfaces allowing easy querying of these data are typically lacking. We present "Entrez Neuron", a pilot neuron-centric interface that allows for keyword-based queries against a coherent repository of OWL ontologies. These ontologies describe neuronal structures, physiology, mathematical models and microscopy images. The returned query results are organized hierarchically according to brain architecture. Where possible, the application makes use of entities from the Open Biomedical Ontologies (OBO) and the 'HCLS knowledgebase' developed by the W3C Interest Group for Health Care and Life Science. It makes use of the emerging RDFa standard to embed ontology fragments and semantic annotations within its HTML-based user interface. The application and underlying ontologies demonstrate how Semantic Web technologies can be used for information integration within a curated information repository and between curated information repositories. It also demonstrates how information integration can be accomplished on the client side, through simple copying and pasting of portions of documents that contain RDFa markup.
Lee, Byungwook; Kim, Taehyung; Kim, Seon-Kyu; Lee, Kwang H; Lee, Doheon
2007-01-01
With the advent of automated and high-throughput techniques, the number of patent applications containing biological sequences has been increasing rapidly. However, they have attracted relatively little attention compared to other sequence resources. We have built a database server called Patome, which contains biological sequence data disclosed in patents and published applications, as well as their analysis information. The analysis is divided into two steps. The first is an annotation step in which the disclosed sequences were annotated with RefSeq database. The second is an association step where the sequences were linked to Entrez Gene, OMIM and GO databases, and their results were saved as a gene-patent table. From the analysis, we found that 55% of human genes were associated with patenting. The gene-patent table can be used to identify whether a particular gene or disease is related to patenting. Patome is available at http://www.patome.org/; the information is updated bimonthly.
Lee, Byungwook; Kim, Taehyung; Kim, Seon-Kyu; Lee, Kwang H.; Lee, Doheon
2007-01-01
With the advent of automated and high-throughput techniques, the number of patent applications containing biological sequences has been increasing rapidly. However, they have attracted relatively little attention compared to other sequence resources. We have built a database server called Patome, which contains biological sequence data disclosed in patents and published applications, as well as their analysis information. The analysis is divided into two steps. The first is an annotation step in which the disclosed sequences were annotated with RefSeq database. The second is an association step where the sequences were linked to Entrez Gene, OMIM and GO databases, and their results were saved as a gene–patent table. From the analysis, we found that 55% of human genes were associated with patenting. The gene–patent table can be used to identify whether a particular gene or disease is related to patenting. Patome is available at ; the information is updated bimonthly. PMID:17085479
Anthrax, Toxins and Vaccines: A 125-Year Journey Targeting Bacillus anthracis
2009-01-01
response. More promising, perhaps, is the use of probiotics generally regarded as safe, such as Lactobacillus spp. expressing PA fused to a peptide that...antigens from probiotic lactic acid bacteria. Expert Rev. Vaccines 7(2), 163-174 (2008). 184 Chen J, Anderson JB, DeWeese-Scott C et al. MMDB: Entrez’s
2017-12-01
for the expression of spontaneous activity in damaged sensory axons of mice. The Journal of Physiology 550, 921-926 3. Milligan, E.D. & Linda Watkins ...http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus &list_uids=19833175 8. Watkins , L.R., Hutchinson, M.R., Rice, K.C
Samwald, Matthias; Lim, Ernest; Masiar, Peter; Marenco, Luis; Chen, Huajun; Morse, Thomas; Mutalik, Pradeep; Shepherd, Gordon; Miller, Perry; Cheung, Kei-Hoi
2013-01-01
The amount of biomedical data available in Semantic Web formats has been rapidly growing in recent years. While these formats are machine-friendly, user-friendly web interfaces allowing easy querying of these data are typically lacking. We present “Entrez Neuron”, a pilot neuron-centric interface that allows for keyword-based queries against a coherent repository of OWL ontologies. These ontologies describe neuronal structures, physiology, mathematical models and microscopy images. The returned query results are organized hierarchically according to brain architecture. Where possible, the application makes use of entities from the Open Biomedical Ontologies (OBO) and the ‘HCLS knowledgebase’ developed by the W3C Interest Group for Health Care and Life Science. It makes use of the emerging RDFa standard to embed ontology fragments and semantic annotations within its HTML-based user interface. The application and underlying ontologies demonstrates how Semantic Web technologies can be used for information integration within a curated information repository and between curated information repositories. It also demonstrates how information integration can be accomplished on the client side, through simple copying and pasting of portions of documents that contain RDFa markup. PMID:19745321
Jani, Saurin D; Argraves, Gary L; Barth, Jeremy L; Argraves, W Scott
2010-04-01
An important objective of DNA microarray-based gene expression experimentation is determining inter-relationships that exist between differentially expressed genes and biological processes, molecular functions, cellular components, signaling pathways, physiologic processes and diseases. Here we describe GeneMesh, a web-based program that facilitates analysis of DNA microarray gene expression data. GeneMesh relates genes in a query set to categories available in the Medical Subject Headings (MeSH) hierarchical index. The interface enables hypothesis driven relational analysis to a specific MeSH subcategory (e.g., Cardiovascular System, Genetic Processes, Immune System Diseases etc.) or unbiased relational analysis to broader MeSH categories (e.g., Anatomy, Biological Sciences, Disease etc.). Genes found associated with a given MeSH category are dynamically linked to facilitate tabular and graphical depiction of Entrez Gene information, Gene Ontology information, KEGG metabolic pathway diagrams and intermolecular interaction information. Expression intensity values of groups of genes that cluster in relation to a given MeSH category, gene ontology or pathway can be displayed as heat maps of Z score-normalized values. GeneMesh operates on gene expression data derived from a number of commercial microarray platforms including Affymetrix, Agilent and Illumina. GeneMesh is a versatile web-based tool for testing and developing new hypotheses through relating genes in a query set (e.g., differentially expressed genes from a DNA microarray experiment) to descriptors making up the hierarchical structure of the National Library of Medicine controlled vocabulary thesaurus, MeSH. The system further enhances the discovery process by providing links between sets of genes associated with a given MeSH category to a rich set of html linked tabular and graphic information including Entrez Gene summaries, gene ontologies, intermolecular interactions, overlays of genes onto KEGG pathway diagrams and heatmaps of expression intensity values. GeneMesh is freely available online at http://proteogenomics.musc.edu/genemesh/.
The BioGRID Interaction Database: 2011 update
Stark, Chris; Breitkreutz, Bobby-Joe; Chatr-aryamontri, Andrew; Boucher, Lorrie; Oughtred, Rose; Livstone, Michael S.; Nixon, Julie; Van Auken, Kimberly; Wang, Xiaodong; Shi, Xiaoqi; Reguly, Teresa; Rust, Jennifer M.; Winter, Andrew; Dolinski, Kara; Tyers, Mike
2011-01-01
The Biological General Repository for Interaction Datasets (BioGRID) is a public database that archives and disseminates genetic and protein interaction data from model organisms and humans (http://www.thebiogrid.org). BioGRID currently holds 347 966 interactions (170 162 genetic, 177 804 protein) curated from both high-throughput data sets and individual focused studies, as derived from over 23 000 publications in the primary literature. Complete coverage of the entire literature is maintained for budding yeast (Saccharomyces cerevisiae), fission yeast (Schizosaccharomyces pombe) and thale cress (Arabidopsis thaliana), and efforts to expand curation across multiple metazoan species are underway. The BioGRID houses 48 831 human protein interactions that have been curated from 10 247 publications. Current curation drives are focused on particular areas of biology to enable insights into conserved networks and pathways that are relevant to human health. The BioGRID 3.0 web interface contains new search and display features that enable rapid queries across multiple data types and sources. An automated Interaction Management System (IMS) is used to prioritize, coordinate and track curation across international sites and projects. BioGRID provides interaction data to several model organism databases, resources such as Entrez-Gene and other interaction meta-databases. The entire BioGRID 3.0 data collection may be downloaded in multiple file formats, including PSI MI XML. Source code for BioGRID 3.0 is freely available without any restrictions. PMID:21071413
ARCPHdb: A comprehensive protein database for SF1 and SF2 helicase from archaea.
Moukhtar, Mirna; Chaar, Wafi; Abdel-Razzak, Ziad; Khalil, Mohamad; Taha, Samir; Chamieh, Hala
2017-01-01
Superfamily 1 and Superfamily 2 helicases, two of the largest helicase protein families, play vital roles in many biological processes including replication, transcription and translation. Study of helicase proteins in the model microorganisms of archaea have largely contributed to the understanding of their function, architecture and assembly. Based on a large phylogenomics approach, we have identified and classified all SF1 and SF2 protein families in ninety five sequenced archaea genomes. Here we developed an online webserver linked to a specialized protein database named ARCPHdb to provide access for SF1 and SF2 helicase families from archaea. ARCPHdb was implemented using MySQL relational database. Web interfaces were developed using Netbeans. Data were stored according to UniProt accession numbers, NCBI Ref Seq ID, PDB IDs and Entrez Databases. A user-friendly interactive web interface has been developed to browse, search and download archaeal helicase protein sequences, their available 3D structure models, and related documentation available in the literature provided by ARCPHdb. The database provides direct links to matching external databases. The ARCPHdb is the first online database to compile all protein information on SF1 and SF2 helicase from archaea in one platform. This database provides essential resource information for all researchers interested in the field. Copyright © 2016 Elsevier Ltd. All rights reserved.
dbSUPER: a database of super-enhancers in mouse and human genome
Khan, Aziz; Zhang, Xuegong
2016-01-01
Super-enhancers are clusters of transcriptional enhancers that drive cell-type-specific gene expression and are crucial to cell identity. Many disease-associated sequence variations are enriched in super-enhancer regions of disease-relevant cell types. Thus, super-enhancers can be used as potential biomarkers for disease diagnosis and therapeutics. Current studies have identified super-enhancers in more than 100 cell types and demonstrated their functional importance. However, a centralized resource to integrate all these findings is not currently available. We developed dbSUPER (http://bioinfo.au.tsinghua.edu.cn/dbsuper/), the first integrated and interactive database of super-enhancers, with the primary goal of providing a resource for assistance in further studies related to transcriptional control of cell identity and disease. dbSUPER provides a responsive and user-friendly web interface to facilitate efficient and comprehensive search and browsing. The data can be easily sent to Galaxy instances, GREAT and Cistrome web-servers for downstream analysis, and can also be visualized in the UCSC genome browser where custom tracks can be added automatically. The data can be downloaded and exported in variety of formats. Furthermore, dbSUPER lists genes associated with super-enhancers and also links to external databases such as GeneCards, UniProt and Entrez. dbSUPER also provides an overlap analysis tool to annotate user-defined regions. We believe dbSUPER is a valuable resource for the biology and genetic research communities. PMID:26438538
DESM: portal for microbial knowledge exploration systems.
Salhi, Adil; Essack, Magbubah; Radovanovic, Aleksandar; Marchand, Benoit; Bougouffa, Salim; Antunes, Andre; Simoes, Marta Filipa; Lafi, Feras F; Motwalli, Olaa A; Bokhari, Ameerah; Malas, Tariq; Amoudi, Soha Al; Othum, Ghofran; Allam, Intikhab; Mineta, Katsuhiko; Gao, Xin; Hoehndorf, Robert; C Archer, John A; Gojobori, Takashi; Bajic, Vladimir B
2016-01-04
Microorganisms produce an enormous variety of chemical compounds. It is of general interest for microbiology and biotechnology researchers to have means to explore information about molecular and genetic basis of functioning of different microorganisms and their ability for bioproduction. To enable such exploration, we compiled 45 topic-specific knowledgebases (KBs) accessible through DESM portal (www.cbrc.kaust.edu.sa/desm). The KBs contain information derived through text-mining of PubMed information and complemented by information data-mined from various other resources (e.g. ChEBI, Entrez Gene, GO, KOBAS, KEGG, UniPathways, BioGrid). All PubMed records were indexed using 4,538,278 concepts from 29 dictionaries, with 1 638 986 records utilized in KBs. Concepts used are normalized whenever possible. Most of the KBs focus on a particular type of microbial activity, such as production of biocatalysts or nutraceuticals. Others are focused on specific categories of microorganisms, e.g. streptomyces or cyanobacteria. KBs are all structured in a uniform manner and have a standardized user interface. Information exploration is enabled through various searches. Users can explore statistically most significant concepts or pairs of concepts, generate hypotheses, create interactive networks of associated concepts and export results. We believe DESM will be a useful complement to the existing resources to benefit microbiology and biotechnology research. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.
Kim, Mara; Cooper, Brian A.; Venkat, Rohit; Phillips, Julie B.; Eidem, Haley R.; Hirbo, Jibril; Nutakki, Sashank; Williams, Scott M.; Muglia, Louis J.; Capra, J. Anthony; Petren, Kenneth; Abbot, Patrick; Rokas, Antonis; McGary, Kriston L.
2016-01-01
Mammalian gestation and pregnancy are fast evolving processes that involve the interaction of the fetal, maternal and paternal genomes. Version 1.0 of the GEneSTATION database (http://genestation.org) integrates diverse types of omics data across mammals to advance understanding of the genetic basis of gestation and pregnancy-associated phenotypes and to accelerate the translation of discoveries from model organisms to humans. GEneSTATION is built using tools from the Generic Model Organism Database project, including the biology-aware database CHADO, new tools for rapid data integration, and algorithms that streamline synthesis and user access. GEneSTATION contains curated life history information on pregnancy and reproduction from 23 high-quality mammalian genomes. For every human gene, GEneSTATION contains diverse evolutionary (e.g. gene age, population genetic and molecular evolutionary statistics), organismal (e.g. tissue-specific gene and protein expression, differential gene expression, disease phenotype), and molecular data types (e.g. Gene Ontology Annotation, protein interactions), as well as links to many general (e.g. Entrez, PubMed) and pregnancy disease-specific (e.g. PTBgene, dbPTB) databases. By facilitating the synthesis of diverse functional and evolutionary data in pregnancy-associated tissues and phenotypes and enabling their quick, intuitive, accurate and customized meta-analysis, GEneSTATION provides a novel platform for comprehensive investigation of the function and evolution of mammalian pregnancy. PMID:26567549
Concept annotation in the CRAFT corpus.
Bada, Michael; Eckert, Miriam; Evans, Donald; Garcia, Kristin; Shipley, Krista; Sitnikov, Dmitry; Baumgartner, William A; Cohen, K Bretonnel; Verspoor, Karin; Blake, Judith A; Hunter, Lawrence E
2012-07-09
Manually annotated corpora are critical for the training and evaluation of automated methods to identify concepts in biomedical text. This paper presents the concept annotations of the Colorado Richly Annotated Full-Text (CRAFT) Corpus, a collection of 97 full-length, open-access biomedical journal articles that have been annotated both semantically and syntactically to serve as a research resource for the biomedical natural-language-processing (NLP) community. CRAFT identifies all mentions of nearly all concepts from nine prominent biomedical ontologies and terminologies: the Cell Type Ontology, the Chemical Entities of Biological Interest ontology, the NCBI Taxonomy, the Protein Ontology, the Sequence Ontology, the entries of the Entrez Gene database, and the three subontologies of the Gene Ontology. The first public release includes the annotations for 67 of the 97 articles, reserving two sets of 15 articles for future text-mining competitions (after which these too will be released). Concept annotations were created based on a single set of guidelines, which has enabled us to achieve consistently high interannotator agreement. As the initial 67-article release contains more than 560,000 tokens (and the full set more than 790,000 tokens), our corpus is among the largest gold-standard annotated biomedical corpora. Unlike most others, the journal articles that comprise the corpus are drawn from diverse biomedical disciplines and are marked up in their entirety. Additionally, with a concept-annotation count of nearly 100,000 in the 67-article subset (and more than 140,000 in the full collection), the scale of conceptual markup is also among the largest of comparable corpora. The concept annotations of the CRAFT Corpus have the potential to significantly advance biomedical text mining by providing a high-quality gold standard for NLP systems. The corpus, annotation guidelines, and other associated resources are freely available at http://bionlp-corpora.sourceforge.net/CRAFT/index.shtml.
Concept annotation in the CRAFT corpus
2012-01-01
Background Manually annotated corpora are critical for the training and evaluation of automated methods to identify concepts in biomedical text. Results This paper presents the concept annotations of the Colorado Richly Annotated Full-Text (CRAFT) Corpus, a collection of 97 full-length, open-access biomedical journal articles that have been annotated both semantically and syntactically to serve as a research resource for the biomedical natural-language-processing (NLP) community. CRAFT identifies all mentions of nearly all concepts from nine prominent biomedical ontologies and terminologies: the Cell Type Ontology, the Chemical Entities of Biological Interest ontology, the NCBI Taxonomy, the Protein Ontology, the Sequence Ontology, the entries of the Entrez Gene database, and the three subontologies of the Gene Ontology. The first public release includes the annotations for 67 of the 97 articles, reserving two sets of 15 articles for future text-mining competitions (after which these too will be released). Concept annotations were created based on a single set of guidelines, which has enabled us to achieve consistently high interannotator agreement. Conclusions As the initial 67-article release contains more than 560,000 tokens (and the full set more than 790,000 tokens), our corpus is among the largest gold-standard annotated biomedical corpora. Unlike most others, the journal articles that comprise the corpus are drawn from diverse biomedical disciplines and are marked up in their entirety. Additionally, with a concept-annotation count of nearly 100,000 in the 67-article subset (and more than 140,000 in the full collection), the scale of conceptual markup is also among the largest of comparable corpora. The concept annotations of the CRAFT Corpus have the potential to significantly advance biomedical text mining by providing a high-quality gold standard for NLP systems. The corpus, annotation guidelines, and other associated resources are freely available at http://bionlp-corpora.sourceforge.net/CRAFT/index.shtml. PMID:22776079
Flare-ups after endodontic treatment: a meta-analysis of literature.
Tsesis, Igor; Faivishevsky, Vadim; Fuss, Zvi; Zukerman, Ofer
2008-10-01
The purpose of this study was to determine the frequency of flare-ups and to evaluate factors that affect it by using meta-analysis of results of previous studies. MEDLINE database was searched by using Entrez PubMed search engine and Medical Subject Headings (MeSH) search with EviDents Search Engine to identify the studies dealing with endodontic flare-up phenomenon. The search covered all articles published in dental journals in English from 1966-May 2007, and the relevancy of 119 selected articles was evaluated by reading their titles and abstracts, from which 54 were rejected as irrelevant and 65 were subjected to a suitability test. Six studies that met all the above mentioned criteria were included in the study. Average percentage of incidence of flare-ups for 982 patients was 8.4 (standard deviation +/-57). There were insufficient data to investigate the effect of the influencing factors.
SLIM: an alternative Web interface for MEDLINE/PubMed searches – a preliminary study
Muin, Michael; Fontelo, Paul; Liu, Fang; Ackerman, Michael
2005-01-01
Background With the rapid growth of medical information and the pervasiveness of the Internet, online search and retrieval systems have become indispensable tools in medicine. The progress of Web technologies can provide expert searching capabilities to non-expert information seekers. The objective of the project is to create an alternative search interface for MEDLINE/PubMed searches using JavaScript slider bars. SLIM, or Slider Interface for MEDLINE/PubMed searches, was developed with PHP and JavaScript. Interactive slider bars in the search form controlled search parameters such as limits, filters and MeSH terminologies. Connections to PubMed were done using the Entrez Programming Utilities (E-Utilities). Custom scripts were created to mimic the automatic term mapping process of Entrez. Page generation times for both local and remote connections were recorded. Results Alpha testing by developers showed SLIM to be functionally stable. Page generation times to simulate loading times were recorded the first week of alpha and beta testing. Average page generation times for the index page, previews and searches were 2.94 milliseconds, 0.63 seconds and 3.84 seconds, respectively. Eighteen physicians from the US, Australia and the Philippines participated in the beta testing and provided feedback through an online survey. Most users found the search interface user-friendly and easy to use. Information on MeSH terms and the ability to instantly hide and display abstracts were identified as distinctive features. Conclusion SLIM can be an interactive time-saving tool for online medical literature research that improves user control and capability to instantly refine and refocus search strategies. With continued development and by integrating search limits, methodology filters, MeSH terms and levels of evidence, SLIM may be useful in the practice of evidence-based medicine. PMID:16321145
SLIM: an alternative Web interface for MEDLINE/PubMed searches - a preliminary study.
Muin, Michael; Fontelo, Paul; Liu, Fang; Ackerman, Michael
2005-12-01
With the rapid growth of medical information and the pervasiveness of the Internet, online search and retrieval systems have become indispensable tools in medicine. The progress of Web technologies can provide expert searching capabilities to non-expert information seekers. The objective of the project is to create an alternative search interface for MEDLINE/PubMed searches using JavaScript slider bars. SLIM, or Slider Interface for MEDLINE/PubMed searches, was developed with PHP and JavaScript. Interactive slider bars in the search form controlled search parameters such as limits, filters and MeSH terminologies. Connections to PubMed were done using the Entrez Programming Utilities (E-Utilities). Custom scripts were created to mimic the automatic term mapping process of Entrez. Page generation times for both local and remote connections were recorded. Alpha testing by developers showed SLIM to be functionally stable. Page generation times to simulate loading times were recorded the first week of alpha and beta testing. Average page generation times for the index page, previews and searches were 2.94 milliseconds, 0.63 seconds and 3.84 seconds, respectively. Eighteen physicians from the US, Australia and the Philippines participated in the beta testing and provided feedback through an online survey. Most users found the search interface user-friendly and easy to use. Information on MeSH terms and the ability to instantly hide and display abstracts were identified as distinctive features. SLIM can be an interactive time-saving tool for online medical literature research that improves user control and capability to instantly refine and refocus search strategies. With continued development and by integrating search limits, methodology filters, MeSH terms and levels of evidence, SLIM may be useful in the practice of evidence-based medicine.
Benson, Dennis A; Karsch-Mizrachi, Ilene; Lipman, David J; Ostell, James; Sayers, Eric W
2010-01-01
GenBank is a comprehensive database that contains publicly available nucleotide sequences for more than 300,000 organisms named at the genus level or lower, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects, including whole genome shotgun (WGS) and environmental sampling projects. Most submissions are made using the web-based BankIt or standalone Sequin programs, and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the European Molecular Biology Laboratory Nucleotide Sequence Database in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through the NCBI Entrez retrieval system, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bi-monthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI homepage: www.ncbi.nlm.nih.gov.
Benson, Dennis A; Karsch-Mizrachi, Ilene; Lipman, David J; Ostell, James; Sayers, Eric W
2011-01-01
GenBank® is a comprehensive database that contains publicly available nucleotide sequences for more than 380,000 organisms named at the genus level or lower, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects, including whole genome shotgun (WGS) and environmental sampling projects. Most submissions are made using the web-based BankIt or standalone Sequin programs, and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the European Nucleotide Archive (ENA) and the DNA Data Bank of Japan (DDBJ) ensures worldwide coverage. GenBank is accessible through the NCBI Entrez retrieval system that integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI Homepage: www.ncbi.nlm.nih.gov.
Uneke, Chigozie Jesse; Sombie, Issiaka; Keita, Namoudou; Lokossou, Virgil; Johnson, Ermel; Ongolo-Zogo, Pierre
2017-01-01
In most developing countries including Nigeria, one of the most challenging issues associated with evidence-to-policy link is the capacity constraints of policymakers to access, synthesize, adapt and utilize available research evidence. The purpose of this review is to assess the efforts and various initiatives that have been undertaken to deliberately engage policymakers and other stakeholders in the health sector in Nigeria for the promotion of evidence informed policymaking. A MEDLINE Entrez Pubmed search was performed and studies that investigated policy making process, evidence to policy link, research to policy mechanism, and researchers/policymakers interaction in Nigeria in relation to health policy were sought. Of the 132 publications found, 14(10.6%) fulfilled the study inclusion criteria and were selected and included in the review. Of the fourteen scientific publications identified, 11 of the studies targeted both researchers and policymakers and the principal tool of intervention was training workshops which focused on various aspects of evidence informed policymaking. All the studies indicated positive outcomes and impacts in relation to quantifiable improvement in policymakers' knowledge and competence in evidence to policy process. Capacity strengthening engagement mechanism is needed for both researchers to generate better evidence and for policymakers and health-care professionals to better use available evidence. PMID:28819479
Uneke, Chigozie Jesse; Sombie, Issiaka; Keita, Namoudou; Lokossou, Virgil; Johnson, Ermel; Ongolo-Zogo, Pierre
2017-01-01
In most developing countries including Nigeria, one of the most challenging issues associated with evidence-to-policy link is the capacity constraints of policymakers to access, synthesize, adapt and utilize available research evidence. The purpose of this review is to assess the efforts and various initiatives that have been undertaken to deliberately engage policymakers and other stakeholders in the health sector in Nigeria for the promotion of evidence informed policymaking. A MEDLINE Entrez Pubmed search was performed and studies that investigated policy making process, evidence to policy link, research to policy mechanism, and researchers/policymakers interaction in Nigeria in relation to health policy were sought. Of the 132 publications found, 14(10.6%) fulfilled the study inclusion criteria and were selected and included in the review. Of the fourteen scientific publications identified, 11 of the studies targeted both researchers and policymakers and the principal tool of intervention was training workshops which focused on various aspects of evidence informed policymaking. All the studies indicated positive outcomes and impacts in relation to quantifiable improvement in policymakers' knowledge and competence in evidence to policy process. Capacity strengthening engagement mechanism is needed for both researchers to generate better evidence and for policymakers and health-care professionals to better use available evidence.
Cleary, Robert K; Pomerantz, Richard A; Lampman, Richard M
2006-08-01
This study was designed to develop treatment algorithms for colon, rectal, and anal injuries based on the review of relevant literature. Information was obtained through a MEDLINE ( www.nobi.nih.gov/entrez/query.fcgi ) search, and additional references were obtained through cross-referencing key articles cited in these papers. A total of 203 articles were considered relevant. The management of penetrating and blunt colon, rectal, and anal injuries has evolved during the past 150 years. Since the World War II mandate to divert penetrating colon injuries, primary repair or resection and anastomosis have found an increasing role in patients with nondestructive injuries. A critical review of recent literature better defines the role of primary repair and fecal diversion for these injuries and allows for better algorithms for the management of these injuries.
Interactive text mining with Pipeline Pilot: a bibliographic web-based tool for PubMed.
Vellay, S G P; Latimer, N E Miller; Paillard, G
2009-06-01
Text mining has become an integral part of all research in the medical field. Many text analysis software platforms support particular use cases and only those. We show an example of a bibliographic tool that can be used to support virtually any use case in an agile manner. Here we focus on a Pipeline Pilot web-based application that interactively analyzes and reports on PubMed search results. This will be of interest to any scientist to help identify the most relevant papers in a topical area more quickly and to evaluate the results of query refinement. Links with Entrez databases help both the biologist and the chemist alike. We illustrate this application with Leishmaniasis, a neglected tropical disease, as a case study.
BIOSPIDA: A Relational Database Translator for NCBI.
Hagen, Matthew S; Lee, Eva K
2010-11-13
As the volume and availability of biological databases continue widespread growth, it has become increasingly difficult for research scientists to identify all relevant information for biological entities of interest. Details of nucleotide sequences, gene expression, molecular interactions, and three-dimensional structures are maintained across many different databases. To retrieve all necessary information requires an integrated system that can query multiple databases with minimized overhead. This paper introduces a universal parser and relational schema translator that can be utilized for all NCBI databases in Abstract Syntax Notation (ASN.1). The data models for OMIM, Entrez-Gene, Pubmed, MMDB and GenBank have been successfully converted into relational databases and all are easily linkable helping to answer complex biological questions. These tools facilitate research scientists to locally integrate databases from NCBI without significant workload or development time.
Uneke, C J
2008-06-01
Malaria and typhoid fever still remain diseases of major public health importance in the tropics. Individuals in areas endemic for both the diseases are at substantial risk of contracting both these diseases, either concurrently or an acute infection superimposed on a chronic one. The objective of this report was to systematically review scientific data from studies conducted in the tropics on concurrent malaria and typhoid fever within the last two decades (1987-2007), to highlight the diagnostic challenges and the public health implications. Using the MedLine Entrez-PubMed search, relevant publications were identified for the review via the key words Malaria and Typhoid fever, which yielded 287 entries as of January 2008. Most of the studies reviewed expressed concern that poor diagnosis continues to hinder effective control of concurrent malaria and typhoid fever in the tropics due to: non-specific clinical presentation of the diseases; high prevalence of asymptomatic infections; lack of resources and insufficient access to trained health care providers and facilities; and widespread practice of self-treatment for clinically suspected malaria or typhoid fever. There were considerably higher rates of concurrent malaria and typhoid fever by Widal test compared to the bacteriological culture technique. Although culture technique remains the gold standard in typhoid fever diagnosis, Widal test is still of significant diagnostic value provided judicious interpretation of the test is made against a background of pertinent information. Malaria could be controlled through interventions to minimize human-vector contact, while improved personal hygiene, targeted vaccination campaigns and intensive community health education could help to control typhoid fever in the tropics.
Dataset of breath research manuscripts curated using PubMed search strings from 1995-2016.
Geer Wallace, M Ariel; Pleil, Joachim D
2018-06-01
The data contained in this article are PubMed search strings and search string builders used to curate breath research manuscripts published from 1995-2016 and the respective number of articles found that satisfied the search requirements for selected categories. Breath sampling represents a non-invasive technique that has gained usefulness for public health, clinical, diagnostic, and environmental exposure assessment applications over the years. This data article includes search strings that were utilized to retrieve publications through the PubMed database for different breath research-related topics that were related to the analysis of exhaled breath, exhaled breath condensate (EBC), and exhaled breath aerosol (EBA) as well as the analysis of cellular headspace. Manuscripts were curated for topics including EBC, EBA, Direct MS, GC-MS, LC-MS, alcohol, and sensors. A summary of the number of papers published per year for the data retrieved using each of the search strings is also included. These data can be utilized to discern trends in the number of breath research publications in each of the different topics over time. A supplementary Appendix A containing the titles, author lists, journal names, publication dates, PMID numbers, and EntrezUID numbers for each of the journal articles curated using the finalized search strings for the seven breath research-related topics can also be found within this article. The selected manuscripts can be used to explore the impact that breath research has had on expanding the scientific knowledge in each of the investigated topics.
Balancing the professional and personal.
Armstrong, Alicia Y; Alvero, Ruben J; Dunlow, Susan; Nace, Mary Catherine; Baker, Valerie; Stewart, Elizabeth A
2009-01-01
To review the common roles that physicians pursue away from work and identify related challenges and potential solutions, so that individuals can develop a personalized plan for success in each of the areas. Literature review. University-based and university-affiliated medical centers. No subjects were involved in this literature review. Literature searches in Entrez PubMed and the following Websites: http://www.apgo.org, http://www.psychiatrictimes.com, as well as other data sources. Results of physician surveys and summaries of strategies for achieving work-personal life balance. According to surveys of physicians in various specialties, a majority of physicians have high levels of job, marital, and parental satisfaction. However, professional and personal challenges faced by physicians include struggle with time management, lack of mentorship, and difficulty maintaining intimate relationships. Multiple potentially effective strategies have been described in the literature, including exerting control over hours worked, taking a long view of life that acknowledges the need for changing priorities over time, developing communication skills, seeking counseling services if needed that focus on physician relationships, and simplifying home life whenever possible. Although there are unique challenges in being a physician, partner, and parent, many of the professional challenges faced by physicians are common to many adults in the United States. Self-assessment may help individuals to clarify priorities and develop strategies that can lead to improved personal satisfaction.
Diagnosis, Prevention and Management of Postoperative Pulmonary Edema
Bajwa, SJ Singh; Kulshrestha, A
2012-01-01
Postoperative pulmonary edema is a well-known postoperative complication caused as a result of numerous etiological factors which can be easily detected by a careful surveillance during postoperative period. However, there are no preoperative and intraoperative criteria which can successfully establish the possibilities for development of postoperative pulmonary edema. The aims were to review the possible etiologic and diagnostic challenges in timely detection of postoperative pulmonary edema and to discuss the various management strategies for prevention of this postoperative complication so as to decrease morbidity and mortality. The various search engines for preparation of this manuscript were used which included Entrez (including Pubmed and Pubmed Central), NIH.gov, Medknow.com, Medscape.com, WebMD.com, Scopus, Science Direct, MedHelp.org, yahoo.com and google.com. Manual search was carried out and various text books and journals of anesthesia and critical care medicine were also searched. From the information gathered, it was observed that postoperative cardiogenic pulmonary edema in patients with serious cardiovascular diseases is most common followed by noncardiogenic pulmonary edema which can be due to fluid overload in the postoperative period or it can be negative pressure pulmonary edema (NPPE). NPPE is an important clinical entity in immediate post-extubation period and occurs due to acute upper airway obstruction and creation of acute negative intrathoracic pressure. NPPE carries a good prognosis if promptly diagnosed and appropriately treated with or without mechanical ventilation. PMID:23439791
Lin, Guiting; Reed-Maldonado, Amanda B.; Lin, Maofan; Xin, Zhongcheng; Lue, Tom F.
2016-01-01
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is one of the most common urologic diseases, and no curative treatments have been identified. Low-intensity pulsed ultrasound (LIPUS) has been successfully used in promoting tissue healing, inhibiting inflammation and pain, differentiating stem cells, and stimulating nerve regeneration/muscle regeneration, as well as enhancing angiogenesis. Very recently, LIPUS has been proven an effective approach for CP/CPPS. This review summarizes the possible mechanisms responsible for the therapeutic effect of LIPUS for CP/CPPS. To search publications relevant to the topics of this review, the search engine for life sciences of Entrez was used. We reviewed the available evidence from 1954 through 2015 concerning LIPUS for CP/CPPS. According to the literature, both transrectal and transperineal approaches of LIPUS are effective for CP/CPPS. PMID:27376284
Lin, Guiting; Reed-Maldonado, Amanda B; Lin, Maofan; Xin, Zhongcheng; Lue, Tom F
2016-07-01
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is one of the most common urologic diseases, and no curative treatments have been identified. Low-intensity pulsed ultrasound (LIPUS) has been successfully used in promoting tissue healing, inhibiting inflammation and pain, differentiating stem cells, and stimulating nerve regeneration/muscle regeneration, as well as enhancing angiogenesis. Very recently, LIPUS has been proven an effective approach for CP/CPPS. This review summarizes the possible mechanisms responsible for the therapeutic effect of LIPUS for CP/CPPS. To search publications relevant to the topics of this review, the search engine for life sciences of Entrez was used. We reviewed the available evidence from 1954 through 2015 concerning LIPUS for CP/CPPS. According to the literature, both transrectal and transperineal approaches of LIPUS are effective for CP/CPPS.
RefSeq microbial genomes database: new representation and annotation strategy.
Tatusova, Tatiana; Ciufo, Stacy; Fedorov, Boris; O'Neill, Kathleen; Tolstoy, Igor
2014-01-01
The source of the microbial genomic sequences in the RefSeq collection is the set of primary sequence records submitted to the International Nucleotide Sequence Database public archives. These can be accessed through the Entrez search and retrieval system at http://www.ncbi.nlm.nih.gov/genome. Next-generation sequencing has enabled researchers to perform genomic sequencing at rates that were unimaginable in the past. Microbial genomes can now be sequenced in a matter of hours, which has led to a significant increase in the number of assembled genomes deposited in the public archives. This huge increase in DNA sequence data presents new challenges for the annotation, analysis and visualization bioinformatics tools. New strategies have been developed for the annotation and representation of reference genomes and sequence variations derived from population studies and clinical outbreaks.
BIOSPIDA: A Relational Database Translator for NCBI
Hagen, Matthew S.; Lee, Eva K.
2010-01-01
As the volume and availability of biological databases continue widespread growth, it has become increasingly difficult for research scientists to identify all relevant information for biological entities of interest. Details of nucleotide sequences, gene expression, molecular interactions, and three-dimensional structures are maintained across many different databases. To retrieve all necessary information requires an integrated system that can query multiple databases with minimized overhead. This paper introduces a universal parser and relational schema translator that can be utilized for all NCBI databases in Abstract Syntax Notation (ASN.1). The data models for OMIM, Entrez-Gene, Pubmed, MMDB and GenBank have been successfully converted into relational databases and all are easily linkable helping to answer complex biological questions. These tools facilitate research scientists to locally integrate databases from NCBI without significant workload or development time. PMID:21347013
SORTEZ: a relational translator for NCBI's ASN.1 database.
Hart, K W; Searls, D B; Overton, G C
1994-07-01
The National Center for Biotechnology Information (NCBI) has created a database collection that includes several protein and nucleic acid sequence databases, a biosequence-specific subset of MEDLINE, as well as value-added information such as links between similar sequences. Information in the NCBI database is modeled in Abstract Syntax Notation 1 (ASN.1) an Open Systems Interconnection protocol designed for the purpose of exchanging structured data between software applications rather than as a data model for database systems. While the NCBI database is distributed with an easy-to-use information retrieval system, ENTREZ, the ASN.1 data model currently lacks an ad hoc query language for general-purpose data access. For that reason, we have developed a software package, SORTEZ, that transforms the ASN.1 database (or other databases with nested data structures) to a relational data model and subsequently to a relational database management system (Sybase) where information can be accessed through the relational query language, SQL. Because the need to transform data from one data model and schema to another arises naturally in several important contexts, including efficient execution of specific applications, access to multiple databases and adaptation to database evolution this work also serves as a practical study of the issues involved in the various stages of database transformation. We show that transformation from the ASN.1 data model to a relational data model can be largely automated, but that schema transformation and data conversion require considerable domain expertise and would greatly benefit from additional support tools.
Yasuda, Hideto; Nishimura, Tetsuro; Kamo, Tetsuro; Sanui, Masamitsu; Nango, Eishu; Abe, Takayuki; Takebayashi, Toru; Lefor, Alan Kawarai; Hashimoto, Satoru
2017-05-29
Lower tidal volume ventilation in patients with acute respiratory distress syndrome (ARDS) is a strategy to reduce the plateau pressure and driving pressure to limit ventilator-induced lung injury (VILI). Several randomised controlled trials (RCTs) and meta-analyses showed that limiting both the plateau pressure and the tidal volume decreased mortality, but the optimal plateau pressure to demonstrate a benefit is uncertain. The aim of this systematic review is to investigate the optimal upper limit of plateau pressure in patients with ARDS to prevent VILI and improve clinical outcomes using meta-analysis with and without meta-regression. RCTs comparing two mechanical ventilation strategies will be included, with lower plateau pressure and with higher plateau pressure, among patients with ARDS and acute lung injury. Data sources include MEDLINE via the NCBI Entrez system, Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE and Ichushi, a database of papers in Japanese. Two of three physicians will independently screen trials obtained by search for eligibility, and extract data from included studies onto standardised data recording forms. For each included trial, the risk of bias and the quality of evidence will be evaluated using the Grading of Recommendation Assessment Development and Evaluation system. This study does not require ethical approval. The results of this systematic review and meta-analysis with and without meta-regression will be disseminated through conference presentation and publication in a peer-reviewed journal. CRD42016041924. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Dellaire, G.; Farrall, R.; Bickmore, W.A.
2003-01-01
The Nuclear Protein Database (NPD) is a curated database that contains information on more than 1300 vertebrate proteins that are thought, or are known, to localise to the cell nucleus. Each entry is annotated with information on predicted protein size and isoelectric point, as well as any repeats, motifs or domains within the protein sequence. In addition, information on the sub-nuclear localisation of each protein is provided and the biological and molecular functions are described using Gene Ontology (GO) terms. The database is searchable by keyword, protein name, sub-nuclear compartment and protein domain/motif. Links to other databases are provided (e.g. Entrez, SWISS-PROT, OMIM, PubMed, PubMed Central). Thus, NPD provides a gateway through which the nuclear proteome may be explored. The database can be accessed at http://npd.hgu.mrc.ac.uk and is updated monthly. PMID:12520015
A multistage gene normalization system integrating multiple effective methods.
Li, Lishuang; Liu, Shanshan; Li, Lihua; Fan, Wenting; Huang, Degen; Zhou, Huiwei
2013-01-01
Gene/protein recognition and normalization is an important preliminary step for many biological text mining tasks. In this paper, we present a multistage gene normalization system which consists of four major subtasks: pre-processing, dictionary matching, ambiguity resolution and filtering. For the first subtask, we apply the gene mention tagger developed in our earlier work, which achieves an F-score of 88.42% on the BioCreative II GM testing set. In the stage of dictionary matching, the exact matching and approximate matching between gene names and the EntrezGene lexicon have been combined. For the ambiguity resolution subtask, we propose a semantic similarity disambiguation method based on Munkres' Assignment Algorithm. At the last step, a filter based on Wikipedia has been built to remove the false positives. Experimental results show that the presented system can achieve an F-score of 90.1%, outperforming most of the state-of-the-art systems.
Benson, Dennis A.; Karsch-Mizrachi, Ilene; Lipman, David J.; Ostell, James; Wheeler, David L.
2007-01-01
GenBank (R) is a comprehensive database that contains publicly available nucleotide sequences for more than 240 000 named organisms, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Most submissions are made using the web-based BankIt or standalone Sequin programs and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the EMBL Data Library in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through NCBI's retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI Homepage (). PMID:17202161
Release of (and lessons learned from mining) a pioneering large toxicogenomics database.
Sandhu, Komal S; Veeramachaneni, Vamsi; Yao, Xiang; Nie, Alex; Lord, Peter; Amaratunga, Dhammika; McMillian, Michael K; Verheyen, Geert R
2015-07-01
We release the Janssen Toxicogenomics database. This rat liver gene-expression database was generated using Codelink microarrays, and has been used over the past years within Janssen to derive signatures for multiple end points and to classify proprietary compounds. The release consists of gene-expression responses to 124 compounds, selected to give a broad coverage of liver-active compounds. A selection of the compounds were also analyzed on Affymetrix microarrays. The release includes results of an in-house reannotation pipeline to Entrez gene annotations, to classify probes into different confidence classes. High confidence unambiguously annotated probes were used to create gene-level data which served as starting point for cross-platform comparisons. Connectivity map-based similarity methods show excellent agreement between Codelink and Affymetrix runs of the same samples. We also compared our dataset with the Japanese Toxicogenomics Project and observed reasonable agreement, especially for compounds with stronger gene signatures. We describe an R-package containing the gene-level data and show how it can be used for expression-based similarity searches. Comparing the same biological samples run on the Affymetrix and the Codelink platform, good correspondence is observed using connectivity mapping approaches. As expected, this correspondence is smaller when the data are compared with an independent dataset such as TG-GATE. We hope that this collection of gene-expression profiles will be incorporated in toxicogenomics pipelines of users.
GeneLab Phase 2: Integrated Search Data Federation of Space Biology Experimental Data
NASA Technical Reports Server (NTRS)
Tran, P. B.; Berrios, D. C.; Gurram, M. M.; Hashim, J. C. M.; Raghunandan, S.; Lin, S. Y.; Le, T. Q.; Heher, D. M.; Thai, H. T.; Welch, J. D.;
2016-01-01
The GeneLab project is a science initiative to maximize the scientific return of omics data collected from spaceflight and from ground simulations of microgravity and radiation experiments, supported by a data system for a public bioinformatics repository and collaborative analysis tools for these data. The mission of GeneLab is to maximize the utilization of the valuable biological research resources aboard the ISS by collecting genomic, transcriptomic, proteomic and metabolomic (so-called omics) data to enable the exploration of the molecular network responses of terrestrial biology to space environments using a systems biology approach. All GeneLab data are made available to a worldwide network of researchers through its open-access data system. GeneLab is currently being developed by NASA to support Open Science biomedical research in order to enable the human exploration of space and improve life on earth. Open access to Phase 1 of the GeneLab Data Systems (GLDS) was implemented in April 2015. Download volumes have grown steadily, mirroring the growth in curated space biology research data sets (61 as of June 2016), now exceeding 10 TB/month, with over 10,000 file downloads since the start of Phase 1. For the period April 2015 to May 2016, most frequently downloaded were data from studies of Mus musculus (39) followed closely by Arabidopsis thaliana (30), with the remaining downloads roughly equally split across 12 other organisms (each 10 of total downloads). GLDS Phase 2 is focusing on interoperability, supporting data federation, including integrated search capabilities, of GLDS-housed data sets with external data sources, such as gene expression data from NIHNCBIs Gene Expression Omnibus (GEO), proteomic data from EBIs PRIDE system, and metagenomic data from Argonne National Laboratory's MG-RAST. GEO and MG-RAST employ specifications for investigation metadata that are different from those used by the GLDS and PRIDE (e.g., ISA-Tab). The GLDS Phase 2 system will implement a Google-like, full-text search engine using a Service-Oriented Architecture by utilizing publicly available RESTful web services Application Programming Interfaces (e.g., GEO Entrez Programming Utilities) and a Common Metadata Model (CMM) in order to accommodate the different metadata formats between the heterogeneous bioinformatics databases. GLDS Phase 2 completion with fully implemented capabilities will be made available to the general public in September 2017.
Critical factors for the success of orthodontic mini-implants: a systematic review.
Chen, Yan; Kyung, Hee Moon; Zhao, Wen Ting; Yu, Won Jae
2009-03-01
This systematic review was undertaken to discuss factors that affect mini-implants as direct and indirect orthodontic anchorage. The data were collected from electronic databases (Medline [Entrez PubMed], Embase, Web of Science, Cochrane Library, and All Evidence Based Medicine Reviews). Randomized clinical trials, prospective and retrospective clinical studies, and clinical trials concerning the properties, affective factors, and requirements of mini-implants were considered. The titles and abstracts that appeared to fulfill the initial selection criteria were collected by consensus, and the original articles were retrieved and evaluated with a methodologic checklist. A hand search of key orthodontic journals was performed to identify recent unindexed literature. The search strategy resulted in 596 articles. By screening titles and abstracts, 126 articles were identified. After the exclusion criteria were applied, 16 articles remained. The analyzed results of the literature were divided into 2 topics: placement-related and loading-related factors. Mini-implants are effective as anchorage, and their success depends on proper initial mechanical stability and loading quality and quantity.
Finding similar nucleotide sequences using network BLAST searches.
Ladunga, Istvan
2009-06-01
The Basic Local Alignment Search Tool (BLAST) is a keystone of bioinformatics due to its performance and user-friendliness. Beginner and intermediate users will learn how to design and submit blastn and Megablast searches on the Web pages at the National Center for Biotechnology Information. We map nucleic acid sequences to genomes, find identical or similar mRNA, expressed sequence tag, and noncoding RNA sequences, and run Megablast searches, which are much faster than blastn. Understanding results is assisted by taxonomy reports, genomic views, and multiple alignments. We interpret expected frequency thresholds, biological significance, and statistical significance. Weak hits provide no evidence, but hints for further analyses. We find genes that may code for homologous proteins by translated BLAST. We reduce false positives by filtering out low-complexity regions. Parsed BLAST results can be integrated into analysis pipelines. Links in the output connect to Entrez, PUBMED, structural, sequence, interaction, and expression databases. This facilitates integration with a wide spectrum of biological knowledge.
Benson, Dennis A; Karsch-Mizrachi, Ilene; Lipman, David J; Ostell, James; Wheeler, David L
2007-01-01
GenBank (R) is a comprehensive database that contains publicly available nucleotide sequences for more than 240 000 named organisms, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Most submissions are made using the web-based BankIt or standalone Sequin programs and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the EMBL Data Library in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through NCBI's retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI Homepage (www.ncbi.nlm.nih.gov).
Benson, Dennis A; Karsch-Mizrachi, Ilene; Lipman, David J; Ostell, James; Wheeler, David L
2005-01-01
GenBank is a comprehensive database that contains publicly available DNA sequences for more than 165,000 named organisms, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Most submissions are made using the web-based BankIt or standalone Sequin programs and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the EMBL Data Library in the UK and the DNA Data Bank of Japan helps to ensure worldwide coverage. GenBank is accessible through NCBI's retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, go to the NCBI Homepage at http://www.ncbi.nlm.nih.gov.
Benson, Dennis A; Karsch-Mizrachi, Ilene; Lipman, David J; Ostell, James; Wheeler, David L
2006-01-01
GenBank (R) is a comprehensive database that contains publicly available DNA sequences for more than 205 000 named organisms, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Most submissions are made using the Web-based BankIt or standalone Sequin programs and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the EMBL Data Library in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through NCBI's retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, go to the NCBI Homepage at www.ncbi.nlm.nih.gov.
Benson, Dennis A; Karsch-Mizrachi, Ilene; Lipman, David J; Ostell, James; Wheeler, David L
2008-01-01
GenBank (R) is a comprehensive database that contains publicly available nucleotide sequences for more than 260 000 named organisms, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Most submissions are made using the web-based BankIt or standalone Sequin programs and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the European Molecular Biology Laboratory Nucleotide Sequence Database in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through NCBI's retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI Homepage: www.ncbi.nlm.nih.gov.
Benson, Dennis A.; Karsch-Mizrachi, Ilene; Lipman, David J.; Ostell, James; Wheeler, David L.
2008-01-01
GenBank (R) is a comprehensive database that contains publicly available nucleotide sequences for more than 260 000 named organisms, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Most submissions are made using the web-based BankIt or standalone Sequin programs and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the European Molecular Biology Laboratory Nucleotide Sequence Database in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through NCBI's retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI Homepage: www.ncbi.nlm.nih.gov PMID:18073190
CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.
Marchler-Bauer, Aron; Bo, Yu; Han, Lianyi; He, Jane; Lanczycki, Christopher J; Lu, Shennan; Chitsaz, Farideh; Derbyshire, Myra K; Geer, Renata C; Gonzales, Noreen R; Gwadz, Marc; Hurwitz, David I; Lu, Fu; Marchler, Gabriele H; Song, James S; Thanki, Narmada; Wang, Zhouxi; Yamashita, Roxanne A; Zhang, Dachuan; Zheng, Chanjuan; Geer, Lewis Y; Bryant, Stephen H
2017-01-04
NCBI's Conserved Domain Database (CDD) aims at annotating biomolecular sequences with the location of evolutionarily conserved protein domain footprints, and functional sites inferred from such footprints. An archive of pre-computed domain annotation is maintained for proteins tracked by NCBI's Entrez database, and live search services are offered as well. CDD curation staff supplements a comprehensive collection of protein domain and protein family models, which have been imported from external providers, with representations of selected domain families that are curated in-house and organized into hierarchical classifications of functionally distinct families and sub-families. CDD also supports comparative analyses of protein families via conserved domain architectures, and a recent curation effort focuses on providing functional characterizations of distinct subfamily architectures using SPARCLE: Subfamily Protein Architecture Labeling Engine. CDD can be accessed at https://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml. Published by Oxford University Press on behalf of Nucleic Acids Research 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders.
Hamosh, Ada; Scott, Alan F; Amberger, Joanna S; Bocchini, Carol A; McKusick, Victor A
2005-01-01
Online Mendelian Inheritance in Man (OMIM) is a comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics. Started by Dr Victor A. McKusick as the definitive reference Mendelian Inheritance in Man, OMIM (http://www.ncbi.nlm.nih.gov/omim/) is now distributed electronically by the National Center for Biotechnology Information, where it is integrated with the Entrez suite of databases. Derived from the biomedical literature, OMIM is written and edited at Johns Hopkins University with input from scientists and physicians around the world. Each OMIM entry has a full-text summary of a genetically determined phenotype and/or gene and has numerous links to other genetic databases such as DNA and protein sequence, PubMed references, general and locus-specific mutation databases, HUGO nomenclature, MapViewer, GeneTests, patient support groups and many others. OMIM is an easy and straightforward portal to the burgeoning information in human genetics.
Uneke, Chigozie Jesse; Sombie, Issiaka; Keita, Namoudou; Lokossou, Virgil; Johnson, Ermel; Ongolo-Zogo, Pierre
2016-01-01
The introduction of implementation science into maternal, newborn and child health (MNCH) research has facilitated better methods to improve uptake of research findings into practices. With increase in implementation research related to MNCH world-wide, stronger scientific evidence are now available and have improved MNCH policies in many countries including Nigeria. The purpose of this study was to review MNCH implementation studies undertaken in Nigeria in order to understand the extent the evidence generated informed better policy. This study was a systematic review. A MEDLINE Entrez PubMed search was performed in August 2015 and implementation studies that investigated MNCH in Nigeria from 1966 to 2015 in relation to health policy were sought. Search key words included Nigeria, health policy, maternal, newborn, and child health. Only policy relevant studies that were implementation or intervention research which generated evidence to improve MNCH in Nigeria were eligible and were selected. A total of 18 relevant studies that fulfilled the study inclusion criteria were identified out of 471 studies found. These studies generated high quality policy relevance evidence relating to task shifting, breastfeeding practices, maternal nutrition, childhood immunization, kangaroo mother care (KMC), prevention of maternal to child transmission of HIV, etc. These indicated significant improvements in maternal health outcomes in localities and health facilities where the studies were undertaken. There is a dire need for more implementation research related to MNCH in low income settings because the priority for improved MNCH outcome is not so much the development of new technologies but solving implementation issues, such as how to scale up and evaluate interventions within complex health systems.
Delay in indexing articles published in major pharmacy practice journals.
Rodriguez, Ryan W
2014-02-15
The delay in time from entry in the PubMed database to indexing with medical subject heading (MeSH) terms for articles published in three major pharmacy practice journals was evaluated. In April 2013, MEDLINE data were retrieved for articles published in the American Journal of Health-System Pharmacy (AJHP), the Annals of Pharmacotherapy, and Pharmacotherapy between January 1, 2010, and December 31, 2011. Data collected for each article included the PubMed entry date, MeSH indexing date, and publication type. The PubMed entry date was defined as the Entrez date, the date the citation was added to the PubMed database. Medians and interquartile ranges (IQRs) were calculated for the time to indexing of articles and for the age of unindexed articles. The proportion of unindexed articles was also calculated. A total of 1626 publications were reviewed. Overall, the median time to indexing with MeSH terms was 114 days (IQR, 98-141 days): 107 days (IQR, 94-129 days) for AJHP, 131 days (IQR, 104-157 days) for Annals of Pharmacotherapy, and 114 days (IQR, 99-128 days) for Pharmacotherapy. The median age of unindexed articles was 807 days (IQR, 671-807 days). An analysis of three major pharmacy practice journals showed that the median time to indexing articles published in 2010 and 2011 was 114 days. While all articles from AJHP and Pharmacotherapy were indexed, 40 articles from Annals of Pharmacotherapy remained unindexed.
Yoshimatsu, Kayo; Kawano, Noriaki; Kawahara, Nobuo; Akiyama, Hiroshi; Teshima, Reiko; Nishijima, Masahiro
2012-01-01
Developments in the use of genetically modified plants for human and livestock health and phytoremediation were surveyed using information retrieved from Entrez PubMed, Chemical Abstracts Service, Google, congress abstracts and proceedings of related scientific societies, scientific journals, etc. Information obtained was classified into 8 categories according to the research objective and the usage of the transgenic plants as 1: nutraceuticals (functional foods), 2: oral vaccines, 3: edible curatives, 4: vaccine antigens, 5: therapeutic antibodies, 6: curatives, 7: diagnostic agents and reagents, and 8: phytoremediation. In total, 405 cases were collected from 2006 to 2010. The numbers of cases were 120 for nutraceuticals, 65 for oral vaccines, 25 for edible curatives, 36 for vaccine antigens, 36 for therapeutic antibodies, 76 for curatives, 15 for diagnostic agents and reagents, and 40 for phytoremediation (sum of each cases was 413 because some reports were related to several categories). Nutraceuticals, oral vaccines and curatives were predominant. The most frequently used edible crop was rice (51 cases), and tomato (28 cases), lettuce (22 cases), potato (18 cases), corn (15 cases) followed.
Wheeler, David
2007-01-01
GenBank(R) is a comprehensive database of publicly available DNA sequences for more than 205,000 named organisms and for more than 60,000 within the embryophyta, obtained through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Daily data exchange with the European Molecular Biology Laboratory (EMBL) in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through the National Center for Biotechnology Information (NCBI) retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases with taxonomy, genome, mapping, protein structure, and domain information and the biomedical journal literature through PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available through FTP. GenBank usage scenarios ranging from local analyses of the data available through FTP to online analyses supported by the NCBI Web-based tools are discussed. To access GenBank and its related retrieval and analysis services, go to the NCBI Homepage at http://www.ncbi.nlm.nih.gov.
Benson, Dennis A; Karsch-Mizrachi, Ilene; Lipman, David J; Ostell, James; Sayers, Eric W
2009-01-01
GenBank is a comprehensive database that contains publicly available nucleotide sequences for more than 300,000 organisms named at the genus level or lower, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Most submissions are made using the web-based BankIt or standalone Sequin programs, and accession numbers are assigned by GenBank(R) staff upon receipt. Daily data exchange with the European Molecular Biology Laboratory Nucleotide Sequence Database in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through the National Center for Biotechnology Information (NCBI) Entrez retrieval system, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI Homepage: www.ncbi.nlm.nih.gov.
Azamian, Zeinab; Shirban, Farinaz
2016-01-01
It is very difficult to diagnose and treat Class III malocclusion. This type of malocclusion involves a number of cranial base and maxillary and mandibular skeletal and dental compensation components. In Class III malocclusion originating from mandibular prognathism, orthodontic treatment in growing patients is not a good choice and in most cases orthognathic surgery is recommended after the end of growth. Approximately 30–40% of Class III patients exhibit some degree of maxillary deficiency; therefore, devices can be used for maxillary protraction for orthodontic treatment in early mixed dentition. In cases in which dental components are primarily responsible for Class III malocclusion, early therapeutic intervention is recommended. An electronic search was conducted using the Medline database (Entrez PubMed), the Cochrane Collaboration Oral Health Group Database of Clinical Trials, Science Direct, and Scopus. In this review article, we described the treatment options for Class III malocclusion in growing patient with an emphasis on maxillary protraction. It seems that the most important factor for treatment of Class III malocclusion in growing patient is case selection. PMID:27144056
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders.
Hamosh, Ada; Scott, Alan F; Amberger, Joanna; Bocchini, Carol; Valle, David; McKusick, Victor A
2002-01-01
Online Mendelian Inheritance in Man (OMIM) is a comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support research and education in human genomics and the practice of clinical genetics. Started by Dr Victor A. McKusick as the definitive reference Mendelian Inheritance in Man, OMIM (www.ncbi.nlm.nih.gov/omim) is now distributed electronically by the National Center for Biotechnology Information (NCBI), where it is integrated with the Entrez suite of databases. Derived from the biomedical literature, OMIM is written and edited at Johns Hopkins University with input from scientists and physicians around the world. Each OMIM entry has a full-text summary of a genetically determined phenotype and/or gene and has numerous links to other genetic databases such as DNA and protein sequence, PubMed references, general and locus-specific mutation databases, approved gene nomenclature, and the highly detailed mapviewer, as well as patient support groups and many others. OMIM is an easy and straightforward portal to the burgeoning information in human genetics.
Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases.
Berger, Seth I; Posner, Jeremy M; Ma'ayan, Avi
2007-10-04
In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from low-throughput experimental biomedical research literature, extracted automatically from literature using techniques such as natural language processing (NLP), generated experimentally using high-throughput methods such as yeast-2-hybrid screens, or interactions are predicted using an assortment of computational approaches. Genes or proteins identified as significantly changing in proteomic experiments, or identified as susceptibility disease genes in genomic studies, can be placed in the context of protein interaction networks in order to assign these genes and proteins to pathways and protein complexes. Genes2Networks is a software system that integrates the content of ten mammalian interaction network datasets. Filtering techniques to prune low-confidence interactions were implemented. Genes2Networks is delivered as a web-based service using AJAX. The system can be used to extract relevant subnetworks created from "seed" lists of human Entrez gene symbols. The output includes a dynamic linkable three color web-based network map, with a statistical analysis report that identifies significant intermediate nodes used to connect the seed list. Genes2Networks is powerful web-based software that can help experimental biologists to interpret lists of genes and proteins such as those commonly produced through genomic and proteomic experiments, as well as lists of genes and proteins associated with disease processes. This system can be used to find relationships between genes and proteins from seed lists, and predict additional genes or proteins that may play key roles in common pathways or protein complexes.
GeneTools--application for functional annotation and statistical hypothesis testing.
Beisvag, Vidar; Jünge, Frode K R; Bergum, Hallgeir; Jølsum, Lars; Lydersen, Stian; Günther, Clara-Cecilie; Ramampiaro, Heri; Langaas, Mette; Sandvik, Arne K; Laegreid, Astrid
2006-10-24
Modern biology has shifted from "one gene" approaches to methods for genomic-scale analysis like microarray technology, which allow simultaneous measurement of thousands of genes. This has created a need for tools facilitating interpretation of biological data in "batch" mode. However, such tools often leave the investigator with large volumes of apparently unorganized information. To meet this interpretation challenge, gene-set, or cluster testing has become a popular analytical tool. Many gene-set testing methods and software packages are now available, most of which use a variety of statistical tests to assess the genes in a set for biological information. However, the field is still evolving, and there is a great need for "integrated" solutions. GeneTools is a web-service providing access to a database that brings together information from a broad range of resources. The annotation data are updated weekly, guaranteeing that users get data most recently available. Data submitted by the user are stored in the database, where it can easily be updated, shared between users and exported in various formats. GeneTools provides three different tools: i) NMC Annotation Tool, which offers annotations from several databases like UniGene, Entrez Gene, SwissProt and GeneOntology, in both single- and batch search mode. ii) GO Annotator Tool, where users can add new gene ontology (GO) annotations to genes of interest. These user defined GO annotations can be used in further analysis or exported for public distribution. iii) eGOn, a tool for visualization and statistical hypothesis testing of GO category representation. As the first GO tool, eGOn supports hypothesis testing for three different situations (master-target situation, mutually exclusive target-target situation and intersecting target-target situation). An important additional function is an evidence-code filter that allows users, to select the GO annotations for the analysis. GeneTools is the first "all in one" annotation tool, providing users with a rapid extraction of highly relevant gene annotation data for e.g. thousands of genes or clones at once. It allows a user to define and archive new GO annotations and it supports hypothesis testing related to GO category representations. GeneTools is freely available through www.genetools.no
NCBI2RDF: enabling full RDF-based access to NCBI databases.
Anguita, Alberto; García-Remesal, Miguel; de la Iglesia, Diana; Maojo, Victor
2013-01-01
RDF has become the standard technology for enabling interoperability among heterogeneous biomedical databases. The NCBI provides access to a large set of life sciences databases through a common interface called Entrez. However, the latter does not provide RDF-based access to such databases, and, therefore, they cannot be integrated with other RDF-compliant databases and accessed via SPARQL query interfaces. This paper presents the NCBI2RDF system, aimed at providing RDF-based access to the complete NCBI data repository. This API creates a virtual endpoint for servicing SPARQL queries over different NCBI repositories and presenting to users the query results in SPARQL results format, thus enabling this data to be integrated and/or stored with other RDF-compliant repositories. SPARQL queries are dynamically resolved, decomposed, and forwarded to the NCBI-provided E-utilities programmatic interface to access the NCBI data. Furthermore, we show how our approach increases the expressiveness of the native NCBI querying system, allowing several databases to be accessed simultaneously. This feature significantly boosts productivity when working with complex queries and saves time and effort to biomedical researchers. Our approach has been validated with a large number of SPARQL queries, thus proving its reliability and enhanced capabilities in biomedical environments.
Co-infection of tuberculosis and parasitic diseases in humans: a systematic review
2013-01-01
Co-infection of tuberculosis and parasitic diseases in humans is an important public problem in co-endemic areas in developing countries. However, there is a paucity of studies on co-infection and even fewer reviews. This review examines 44 appropriate papers by PRISMA from 289 papers searched in PubMed via the NCBI Entrez system (no grey literature) up to December 2012 in order to analyze the factors that influence epidemic and host’s immunity of co-infection. The limited evidence in this review indicates that most common parasite species are concurrent with Mycobacterium tuberculosis in multiple organs; socio-demographics such as gender and age, special populations with susceptibility such as renal transplant recipients, patients on maintenance haemodialysis, HIV positive patients and migrants, and living in or coming from co-endemic areas are all likely to have an impact on co-infection. Pulmonary tuberculosis and parasitic diseases were shown to be risk factors for each other. Co-infection may significantly inhibit the host’s immune system, increase antibacterial therapy intolerance and be detrimental to the prognosis of the disease; in addition, infection with parasitic diseases can alter the protective immune response to Bacillus Calmette-Guerin vaccination against Mycobacterium tuberculosis. PMID:23522098
SeqHound: biological sequence and structure database as a platform for bioinformatics research
2002-01-01
Background SeqHound has been developed as an integrated biological sequence, taxonomy, annotation and 3-D structure database system. It provides a high-performance server platform for bioinformatics research in a locally-hosted environment. Results SeqHound is based on the National Center for Biotechnology Information data model and programming tools. It offers daily updated contents of all Entrez sequence databases in addition to 3-D structural data and information about sequence redundancies, sequence neighbours, taxonomy, complete genomes, functional annotation including Gene Ontology terms and literature links to PubMed. SeqHound is accessible via a web server through a Perl, C or C++ remote API or an optimized local API. It provides functionality necessary to retrieve specialized subsets of sequences, structures and structural domains. Sequences may be retrieved in FASTA, GenBank, ASN.1 and XML formats. Structures are available in ASN.1, XML and PDB formats. Emphasis has been placed on complete genomes, taxonomy, domain and functional annotation as well as 3-D structural functionality in the API, while fielded text indexing functionality remains under development. SeqHound also offers a streamlined WWW interface for simple web-user queries. Conclusions The system has proven useful in several published bioinformatics projects such as the BIND database and offers a cost-effective infrastructure for research. SeqHound will continue to develop and be provided as a service of the Blueprint Initiative at the Samuel Lunenfeld Research Institute. The source code and examples are available under the terms of the GNU public license at the Sourceforge site http://sourceforge.net/projects/slritools/ in the SLRI Toolkit. PMID:12401134
Smith, R F; Wiese, B A; Wojzynski, M K; Davison, D B; Worley, K C
1996-05-01
The BCM Search Launcher is an integrated set of World Wide Web (WWW) pages that organize molecular biology-related search and analysis services available on the WWW by function, and provide a single point of entry for related searches. The Protein Sequence Search Page, for example, provides a single sequence entry form for submitting sequences to WWW servers that offer remote access to a variety of different protein sequence search tools, including BLAST, FASTA, Smith-Waterman, BEAUTY, PROSITE, and BLOCKS searches. Other Launch pages provide access to (1) nucleic acid sequence searches, (2) multiple and pair-wise sequence alignments, (3) gene feature searches, (4) protein secondary structure prediction, and (5) miscellaneous sequence utilities (e.g., six-frame translation). The BCM Search Launcher also provides a mechanism to extend the utility of other WWW services by adding supplementary hypertext links to results returned by remote servers. For example, links to the NCBI's Entrez data base and to the Sequence Retrieval System (SRS) are added to search results returned by the NCBI's WWW BLAST server. These links provide easy access to auxiliary information, such as Medline abstracts, that can be extremely helpful when analyzing BLAST data base hits. For new or infrequent users of sequence data base search tools, we have preset the default search parameters to provide the most informative first-pass sequence analysis possible. We have also developed a batch client interface for Unix and Macintosh computers that allows multiple input sequences to be searched automatically as a background task, with the results returned as individual HTML documents directly to the user's system. The BCM Search Launcher and batch client are available on the WWW at URL http:@gc.bcm.tmc.edu:8088/search-launcher.html.
25 years of telepathology research: a bibliometric analysis.
Della Mea, Vincenzo
2011-03-30
The first appearance of the word "telepathology" in a scientific paper can be tracked down to 1986, in a famous editorial of Ronald Weinstein. Since that paper, research in telepathology grew up developing different subfields, including static and dynamic telepathology and more recently virtual microscopy. The present work attempts an analysis of research in telepathology, starting from the tools provided by bibliometrics. A query has been developed to extract papers related to telepathology and virtual microscopy, and it has been then submitted to Pubmed by means of Entrez Utilities functions. Results obtained in XML have been processed through ad-hoc developed PHP scripts, in order to extract data on Authors, countries, and keywords. On PubMed, 967 papers related to telepathology and virtual microscopy have been retrieved, which involved 2904 Authors; corresponding authors were from 37 countries. Of those authors, 2213 co-authored just one paper. Papers were published on 344 different journals, of which only 52 from the Pathology field. An analysis of papers per year has been also attempted, that demonstrates variable research output in time. From the proposed analysis, telepathology seems to have been consistently studied, in time, by about 400 researchers, with occasional participation of many other people. Telepathology research seems also to have varied in time, although some peaks in paper publishing are certainly related to the proceedings of the European congress on telepathology series, when they have been published on journals. However, some clear sign appears that suggests research in traditional telepathology, after a peak in 2000, showed some decline until virtual microscopy became mainstream, topic that currently pushes research again. The low number of clinical trials calls for more randomized studies in telepathology, to enable evidence-based application.
25 years of telepathology research: a bibliometric analysis
2011-01-01
Background The first appearance of the word “telepathology” in a scientific paper can be tracked down to 1986, in a famous editorial of Ronald Weinstein. Since that paper, research in telepathology grew up developing different subfields, including static and dynamic telepathology and more recently virtual microscopy. The present work attempts an analysis of research in telepathology, starting from the tools provided by bibliometrics. Methods A query has been developed to extract papers related to telepathology and virtual microscopy, and it has been then submitted to Pubmed by means of Entrez Utilities functions. Results obtained in XML have been processed through ad-hoc developed PHP scripts, in order to extract data on Authors, countries, and keywords. Results On PubMed, 967 papers related to telepathology and virtual microscopy have been retrieved, which involved 2904 Authors; corresponding authors were from 37 countries. Of those authors, 2213 co-authored just one paper. Papers were published on 344 different journals, of which only 52 from the Pathology field. An analysis of papers per year has been also attempted, that demonstrates variable research output in time. Conclusions From the proposed analysis, telepathology seems to have been consistently studied, in time, by about 400 researchers, with occasional participation of many other people. Telepathology research seems also to have varied in time, although some peaks in paper publishing are certainly related to the proceedings of the European congress on telepathology series, when they have been published on journals. However, some clear sign appears that suggests research in traditional telepathology, after a peak in 2000, showed some decline until virtual microscopy became mainstream, topic that currently pushes research again. The low number of clinical trials calls for more randomized studies in telepathology, to enable evidence-based application. PMID:21489197
Insinga, Ralph P; Liaw, Kai-Li; Johnson, Lisa G; Madeleine, Margaret M
2008-07-01
To describe prevalence and estimated attribution of human papillomavirus (HPV) types in U.S. cervical, vaginal, and vulvar precancers and cancers. U.S. studies reporting HPV typing for cervical intraepithelial neoplasia (CIN), vulvar intraepithelial neoplasia (VIN), and vaginal intraepithelial neoplasia (VaIN) and/or invasive cancers of those sites were gathered from the PubMed database (http://www.ncbi.nlm.nih.gov/sites/entrez/). Selected studies had PCR testing data for > or =10 cases for a disease endpoint. Analytic methods augmented prior reviews of cervical disease with an updated and expanded analysis (including vulvar and vaginal disease), new selection criteria for specimens, and adjustment for histologic type, where possible, among pooled cancer cases. In addition, for analyses of estimated attribution of HPV types, we incorporated accounting methods for lesions infected with multiple HPV types. Data from 22 U.S. studies meeting review eligibility criteria were tabulated. Following adjustment for the presence of multiple HPV types in a single specimen, the top two HPV types contributing to disease were CIN 1 (HPV 16/66; 15.3%), CIN 2/3 (HPV 16/31; 61.9%), cervical cancer (HPV 16/18; 79.2%), VIN 1 (HPV 6/11; 41.7%), VIN 3 (HPV 16/18; 84.0%), vulvar cancer (HPV 16/33; 55.5%), VaIN 3 (HPV 16/18; 65.1%), and vaginal cancer (HPV 16/18; 72.7%). The HPV type distribution and proportion of cases testing positive for any HPV type were observed to vary among U.S. cervical, vulvar, and vaginal neoplasias and by grade of disease. Adjustment for the presence of multitype HPV infections can have an important effect on the estimated attribution of HPV types to disease, particularly for types other than HPV 16.
Insinga, Ralph P.; Liaw, Kai-Li; Johnson, Lisa G.; Madeleine, Margaret M.
2008-01-01
Objectives To describe (1) prevalence and (2) estimated attribution of human papillomavirus (HPV) types in U.S. cervical, vaginal and vulvar precancers and cancers. Methods U.S. studies reporting HPV typing for cervical (CIN), vulvar (VIN) and vaginal (VaIN) intraepithelial neoplasias and/or invasive cancers of those sites were gathered from the PubMed database (http://www.ncbi.nlm.nih.gov/sites/entrez/). Selected studies had polymerase chain reaction testing data for ≥10 cases for a disease endpoint. Analytic methods augmented prior reviews of cervical disease with an updated and expanded analysis (including vulvar and vaginal disease), new selection criteria for specimens, and adjustment for histologic type, where possible, among pooled cancer cases. In addition, for analyses of estimated attribution of HPV types, we incorporated accounting methods for lesions infected with multiple HPV types. Results Data from 22 U.S. studies meeting review eligibility criteria were tabulated. Following adjustment for the presence of multiple HPV types in a single specimen, the top two HPV types contributing to disease were: CIN 1 (HPV 16/66) [15.3%], CIN 2/3 (16/31) [61.9%], cervical cancer (16/18) [79.2%], VIN 1 (6/11) [41.7%], VIN 3 (16/18) [84.0%], vulvar cancer (16/33) [55.5%], VaIN 3 (16/18) [65.1%], vaginal cancer (16/18) [72.7%]. Conclusions The HPV type distribution and proportion of cases testing positive for any HPV type were observed to vary among U.S. cervical, vulvar and vaginal neoplasias and by grade of disease. Adjustment for the presence of multi-type HPV infections can have an important impact on the estimated attribution of HPV types to disease, particularly for types other than HPV 16. PMID:18628412
NCBI2RDF: Enabling Full RDF-Based Access to NCBI Databases
Anguita, Alberto; García-Remesal, Miguel; de la Iglesia, Diana; Maojo, Victor
2013-01-01
RDF has become the standard technology for enabling interoperability among heterogeneous biomedical databases. The NCBI provides access to a large set of life sciences databases through a common interface called Entrez. However, the latter does not provide RDF-based access to such databases, and, therefore, they cannot be integrated with other RDF-compliant databases and accessed via SPARQL query interfaces. This paper presents the NCBI2RDF system, aimed at providing RDF-based access to the complete NCBI data repository. This API creates a virtual endpoint for servicing SPARQL queries over different NCBI repositories and presenting to users the query results in SPARQL results format, thus enabling this data to be integrated and/or stored with other RDF-compliant repositories. SPARQL queries are dynamically resolved, decomposed, and forwarded to the NCBI-provided E-utilities programmatic interface to access the NCBI data. Furthermore, we show how our approach increases the expressiveness of the native NCBI querying system, allowing several databases to be accessed simultaneously. This feature significantly boosts productivity when working with complex queries and saves time and effort to biomedical researchers. Our approach has been validated with a large number of SPARQL queries, thus proving its reliability and enhanced capabilities in biomedical environments. PMID:23984425
MMDB: Entrez’s 3D-structure database
Wang, Yanli; Anderson, John B.; Chen, Jie; Geer, Lewis Y.; He, Siqian; Hurwitz, David I.; Liebert, Cynthia A.; Madej, Thomas; Marchler, Gabriele H.; Marchler-Bauer, Aron; Panchenko, Anna R.; Shoemaker, Benjamin A.; Song, James S.; Thiessen, Paul A.; Yamashita, Roxanne A.; Bryant, Stephen H.
2002-01-01
Three-dimensional structures are now known within many protein families and it is quite likely, in searching a sequence database, that one will encounter a homolog with known structure. The goal of Entrez’s 3D-structure database is to make this information, and the functional annotation it can provide, easily accessible to molecular biologists. To this end Entrez’s search engine provides three powerful features. (i) Sequence and structure neighbors; one may select all sequences similar to one of interest, for example, and link to any known 3D structures. (ii) Links between databases; one may search by term matching in MEDLINE, for example, and link to 3D structures reported in these articles. (iii) Sequence and structure visualization; identifying a homolog with known structure, one may view molecular-graphic and alignment displays, to infer approximate 3D structure. In this article we focus on two features of Entrez’s Molecular Modeling Database (MMDB) not described previously: links from individual biopolymer chains within 3D structures to a systematic taxonomy of organisms represented in molecular databases, and links from individual chains (and compact 3D domains within them) to structure neighbors, other chains (and 3D domains) with similar 3D structure. MMDB may be accessed at http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Structure. PMID:11752307
Constancy and diversity in the flavivirus fusion peptide.
Seligman, Stephen J
2008-02-14
Flaviviruses include the mosquito-borne dengue, Japanese encephalitis, yellow fever and West Nile and the tick-borne encephalitis viruses. They are responsible for considerable world-wide morbidity and mortality. Viral entry is mediated by a conserved fusion peptide containing 16 amino acids located in domain II of the envelope protein E. Highly orchestrated conformational changes initiated by exposure to acidic pH accompany the fusion process and are important factors limiting amino acid changes in the fusion peptide that still permit fusion with host cell membranes in both arthropod and vertebrate hosts. The cell-fusing related agents, growing only in mosquitoes or insect cell lines, possess a different homologous peptide. Analysis of 46 named flaviviruses deposited in the Entrez Nucleotides database extended the constancy in the canonical fusion peptide sequences of mosquito-borne, tick-borne and viruses with no known vector to include more recently-sequenced viruses. The mosquito-borne signature amino acid, G104, was also found in flaviviruses with no known vector and with the cell-fusion related viruses. Despite the constancy in the canonical sequences in pathogenic flaviviruses, mutations were surprisingly frequent with a 27% prevalence of nonsynonymous mutations in yellow fever virus fusion peptide sequences, and 0 to 7.4% prevalence in the others. Six of seven yellow fever patients whose virus had fusion peptide mutations died. In the cell-fusing related agents, not enough sequences have been deposited to estimate reliably the prevalence of fusion peptide mutations. However, the canonical sequences homologous to the fusion peptide and the pattern of disulfide linkages in protein E differed significantly from the other flaviviruses. The constancy of the canonical fusion peptide sequences in the arthropod-borne flaviviruses contrasts with the high prevalence of mutations in most individual viruses. The discrepancy may be the result of a survival advantage accompanying sequence diversity (quasispecies) involving the fusion peptide. Limited clinical data with yellow fever virus suggest that the presence of fusion peptide mutants is not associated with a decreased case fatality rate. The cell-fusing related agents may have substantial differences from other flaviviruses in their mechanism of viral entry into the host cell.
2014-01-01
Background Clinically useful biomarkers for patient stratification and monitoring of disease progression and drug response are in big demand in drug development and for addressing potential safety concerns. Many diseases influence the frequency and phenotype of cells found in the peripheral blood and the transcriptome of blood cells. Changes in cell type composition influence whole blood gene expression analysis results and thus the discovery of true transcript level changes remains a challenge. We propose a robust and reproducible procedure, which includes whole transcriptome gene expression profiling of major subsets of immune cell cells directly sorted from whole blood. Methods Target cells were enriched using magnetic microbeads and an autoMACS® Pro Separator (Miltenyi Biotec). Flow cytometric analysis for purity was performed before and after magnetic cell sorting. Total RNA was hybridized on HGU133 Plus 2.0 expression microarrays (Affymetrix, USA). CEL files signal intensity values were condensed using RMA and a custom CDF file (EntrezGene-based). Results Positive selection by use of MACS® Technology coupled to transcriptomics was assessed for eight different peripheral blood cell types, CD14+ monocytes, CD3+, CD4+, or CD8+ T cells, CD15+ granulocytes, CD19+ B cells, CD56+ NK cells, and CD45+ pan leukocytes. RNA quality from enriched cells was above a RIN of eight. GeneChip analysis confirmed cell type specific transcriptome profiles. Storing whole blood collected in an EDTA Vacutainer® tube at 4°C followed by MACS does not activate sorted cells. Gene expression analysis supports cell enrichment measurements by MACS. Conclusions The proposed workflow generates reproducible cell-type specific transcriptome data which can be translated to clinical settings and used to identify clinically relevant gene expression biomarkers from whole blood samples. This procedure enables the integration of transcriptomics of relevant immune cell subsets sorted directly from whole blood in clinical trial protocols. PMID:25984272
Atlas - a data warehouse for integrative bioinformatics.
Shah, Sohrab P; Huang, Yong; Xu, Tao; Yuen, Macaire M S; Ling, John; Ouellette, B F Francis
2005-02-21
We present a biological data warehouse called Atlas that locally stores and integrates biological sequences, molecular interactions, homology information, functional annotations of genes, and biological ontologies. The goal of the system is to provide data, as well as a software infrastructure for bioinformatics research and development. The Atlas system is based on relational data models that we developed for each of the source data types. Data stored within these relational models are managed through Structured Query Language (SQL) calls that are implemented in a set of Application Programming Interfaces (APIs). The APIs include three languages: C++, Java, and Perl. The methods in these API libraries are used to construct a set of loader applications, which parse and load the source datasets into the Atlas database, and a set of toolbox applications which facilitate data retrieval. Atlas stores and integrates local instances of GenBank, RefSeq, UniProt, Human Protein Reference Database (HPRD), Biomolecular Interaction Network Database (BIND), Database of Interacting Proteins (DIP), Molecular Interactions Database (MINT), IntAct, NCBI Taxonomy, Gene Ontology (GO), Online Mendelian Inheritance in Man (OMIM), LocusLink, Entrez Gene and HomoloGene. The retrieval APIs and toolbox applications are critical components that offer end-users flexible, easy, integrated access to this data. We present use cases that use Atlas to integrate these sources for genome annotation, inference of molecular interactions across species, and gene-disease associations. The Atlas biological data warehouse serves as data infrastructure for bioinformatics research and development. It forms the backbone of the research activities in our laboratory and facilitates the integration of disparate, heterogeneous biological sources of data enabling new scientific inferences. Atlas achieves integration of diverse data sets at two levels. First, Atlas stores data of similar types using common data models, enforcing the relationships between data types. Second, integration is achieved through a combination of APIs, ontology, and tools. The Atlas software is freely available under the GNU General Public License at: http://bioinformatics.ubc.ca/atlas/
Sun, Wen; Asztalos, Elizabeth; Moddemann, Diane; Zwaigenbaum, Lonnie; Walker, Mark; Wen, Shi Wu
2016-01-01
It has been conclusively established that folic acid supplementation prior to and during early pregnancy (up to 12 weeks of gestation) can prevent neural tube defects (NTDs). We hypothesized that folate effects may extend from neuro-structural defects to alterations in neuro-behavioural and emotional skills including autism spectrum disorders (ASDs) and other developmental disorders. The objective of this review was to comprehensively evaluate evidence on the impact of folic acid on neurodevelopment other than NTDs. We conducted an online search of relevant literature compiled by the National Library of Medicine from Medline and EMBASE (searched on Dec 31, 2014: http://www.ncbi.nlm.nih.gov/entrez/query/fcgi and http://www.elsevier.com/online-tools/embase). We first created 3 files (search restricted to English literature) using the following key words: 1) folate or folic acid (171322 papers identified by this search); 2) maternal or pregnancy or pregnant or gestation or gestational or prenatal or antenatal or periconception or periconceptional (1349219 papers identified by this search); and 3) autism or autism spectrum disorders or developmental delay or development or neurodevelopment or mental or cognitive or language or personal-social or gross motor or fine motor or behaviour or intellectual or intelligence or Bayley Scale (8268145 papers identified by this search). We then merged the 3 files and reviewed the papers that addressed these three issues simultaneously. A total of 22 original papers that examined the association between folic acid supplementation in human pregnancy and neurodevelopment/autism were identified after the screening, with 15 studies showing a beneficial effect of folic acid supplementation on neurodevelopment/autism, 6 studies showed no statistically significant difference, while one study showed a harmful effect in > 5 mg folic acid supplementation/day during pregnancy. Folic acid supplementation in pregnancy may have beneficial effects on the neurodevelopment of children beyond its proven effect on NTDs. PMID:27875541
Gao, Yunfei; Sheng, Chao; Xie, Ri-Hua; Sun, Wen; Asztalos, Elizabeth; Moddemann, Diane; Zwaigenbaum, Lonnie; Walker, Mark; Wen, Shi Wu
2016-01-01
It has been conclusively established that folic acid supplementation prior to and during early pregnancy (up to 12 weeks of gestation) can prevent neural tube defects (NTDs). We hypothesized that folate effects may extend from neuro-structural defects to alterations in neuro-behavioural and emotional skills including autism spectrum disorders (ASDs) and other developmental disorders. The objective of this review was to comprehensively evaluate evidence on the impact of folic acid on neurodevelopment other than NTDs. We conducted an online search of relevant literature compiled by the National Library of Medicine from Medline and EMBASE (searched on Dec 31, 2014: http://www.ncbi.nlm.nih.gov/entrez/query/fcgi and http://www.elsevier.com/online-tools/embase). We first created 3 files (search restricted to English literature) using the following key words: 1) folate or folic acid (171322 papers identified by this search); 2) maternal or pregnancy or pregnant or gestation or gestational or prenatal or antenatal or periconception or periconceptional (1349219 papers identified by this search); and 3) autism or autism spectrum disorders or developmental delay or development or neurodevelopment or mental or cognitive or language or personal-social or gross motor or fine motor or behaviour or intellectual or intelligence or Bayley Scale (8268145 papers identified by this search). We then merged the 3 files and reviewed the papers that addressed these three issues simultaneously. A total of 22 original papers that examined the association between folic acid supplementation in human pregnancy and neurodevelopment/autism were identified after the screening, with 15 studies showing a beneficial effect of folic acid supplementation on neurodevelopment/autism, 6 studies showed no statistically significant difference, while one study showed a harmful effect in > 5 mg folic acid supplementation/day during pregnancy. Folic acid supplementation in pregnancy may have beneficial effects on the neurodevelopment of children beyond its proven effect on NTDs.
Canine retraction: A systematic review of different methods used.
Kulshrestha, Rohit S; Tandon, Ragni; Chandra, Pratik
2015-01-01
Canine retraction is a very important step in treatment of patients with crowding, or first premolar extraction cases. In severe crowding cases until, the canines have been distilized to relive the crowding, space to correctly align the incisors will not be available. Correct positioning of the canines after retraction is of great importance for the function, stability, and esthetics. The aim of this systematic review was to examine, in an evidence-based way, which kinds of canine retraction methods/techniques are most effective and which have the least side effects. A literature survey was performed by applying the Medline Database (Entrez PubMed) and Science Direct database covering the period from 1985 to 2014, to find out efficient ways to accomplish canine retraction. Randomized controlled trials (RCTs), prospective and retrospective controlled studies, and clinical trials were included. Two reviewers selected and extracted the data independently and assessed the quality of the retrieved studies. The search strategy resulted in 324 articles, of which 22 met the inclusion criteria. Due to the vast heterogeneity in study methods, the scientific evidence was too weak to evaluate retraction efficiency during space closure. The data so far reviewed proved that elastomeric power chains, elastic threads, magnets, NiTi coil springs, corticotomies, distraction osteogenesis, and laser therapy, all are able to provide optimum rate of tooth movements. All the methods were nearly similar to each other for retraction of canines Most of the techniques lead to anchorage loss in various amounts depending on the methods used. Most of the studies had serious problems with small sample size, confounding factors, lack of method error analysis, and no blinding in measurements. To obtain reliable scientific evidence, controlled RCT's with sufficient sample sizes are needed to determine which method/technique is the most effective in the respective retraction situation. Further studies should also consider patient acceptance and cost analysis as well as implants and minor surgeries for canine retraction.
Atlas – a data warehouse for integrative bioinformatics
Shah, Sohrab P; Huang, Yong; Xu, Tao; Yuen, Macaire MS; Ling, John; Ouellette, BF Francis
2005-01-01
Background We present a biological data warehouse called Atlas that locally stores and integrates biological sequences, molecular interactions, homology information, functional annotations of genes, and biological ontologies. The goal of the system is to provide data, as well as a software infrastructure for bioinformatics research and development. Description The Atlas system is based on relational data models that we developed for each of the source data types. Data stored within these relational models are managed through Structured Query Language (SQL) calls that are implemented in a set of Application Programming Interfaces (APIs). The APIs include three languages: C++, Java, and Perl. The methods in these API libraries are used to construct a set of loader applications, which parse and load the source datasets into the Atlas database, and a set of toolbox applications which facilitate data retrieval. Atlas stores and integrates local instances of GenBank, RefSeq, UniProt, Human Protein Reference Database (HPRD), Biomolecular Interaction Network Database (BIND), Database of Interacting Proteins (DIP), Molecular Interactions Database (MINT), IntAct, NCBI Taxonomy, Gene Ontology (GO), Online Mendelian Inheritance in Man (OMIM), LocusLink, Entrez Gene and HomoloGene. The retrieval APIs and toolbox applications are critical components that offer end-users flexible, easy, integrated access to this data. We present use cases that use Atlas to integrate these sources for genome annotation, inference of molecular interactions across species, and gene-disease associations. Conclusion The Atlas biological data warehouse serves as data infrastructure for bioinformatics research and development. It forms the backbone of the research activities in our laboratory and facilitates the integration of disparate, heterogeneous biological sources of data enabling new scientific inferences. Atlas achieves integration of diverse data sets at two levels. First, Atlas stores data of similar types using common data models, enforcing the relationships between data types. Second, integration is achieved through a combination of APIs, ontology, and tools. The Atlas software is freely available under the GNU General Public License at: PMID:15723693
GoGene: gene annotation in the fast lane.
Plake, Conrad; Royer, Loic; Winnenburg, Rainer; Hakenberg, Jörg; Schroeder, Michael
2009-07-01
High-throughput screens such as microarrays and RNAi screens produce huge amounts of data. They typically result in hundreds of genes, which are often further explored and clustered via enriched GeneOntology terms. The strength of such analyses is that they build on high-quality manual annotations provided with the GeneOntology. However, the weakness is that annotations are restricted to process, function and location and that they do not cover all known genes in model organisms. GoGene addresses this weakness by complementing high-quality manual annotation with high-throughput text mining extracting co-occurrences of genes and ontology terms from literature. GoGene contains over 4,000,000 associations between genes and gene-related terms for 10 model organisms extracted from more than 18,000,000 PubMed entries. It does not cover only process, function and location of genes, but also biomedical categories such as diseases, compounds, techniques and mutations. By bringing it all together, GoGene provides the most recent and most complete facts about genes and can rank them according to novelty and importance. GoGene accepts keywords, gene lists, gene sequences and protein sequences as input and supports search for genes in PubMed, EntrezGene and via BLAST. Since all associations of genes to terms are supported by evidence in the literature, the results are transparent and can be verified by the user. GoGene is available at http://gopubmed.org/gogene.
Migliorati, Marco; Isaia, Luisa; Cassaro, Angela; Rivetti, Alessandro; Silvestrini-Biavati, Francesca; Gastaldo, Laura; Piccardo, Ilaria; Dalessandri, Domenico; Silvestrini-Biavati, Armando
2015-06-01
Plaque increase is a troubling side-effect of fixed orthodontic therapy. This generally arise as a consequence of long-term difficulty in maintaining adequate oral hygiene while wearing multibracket appliances. Demineralization, also known as white spot, causes particular concern as it spoils the aesthetic outcome of the treatment itself, not to mention the integrity of the enamel. To collate the existing literature by evaluating the efficacy of dental hygienist intervention on plaque increase in fixed orthodontics patients. A targeted search of the Medline database (Entrez PubMed), EMBASE, and CENTRAL using relevant Medical Subject Headings was performed. The articles selected were all published before June 2013 and comprised randomized clinical trials, prospective longitudinal controlled clinical trials, and before/after studies onto the plaque increase of fixed appliances. The search strategy yielded 630 articles. Following the application of inclusion and exclusion criteria, 10 articles qualified for the final review. The quality of the retrieved researches ranged from low (one study) to high (one study). Six controlled trials were considered at unknown risk of bias. Data showed that regular patient motivation sessions and mechanical tooth cleaning by a professional dental hygienist help maintaining good oral hygiene during fixed orthodontics. © The Author 2014. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.
Randhawa, Gurinder Jit; Singh, Monika; Grover, Monendra
2011-02-01
The novel proteins introduced into the genetically modified (GM) crops need to be evaluated for the potential allergenicity before their introduction into the food chain to address the safety concerns of consumers. At present, there is no single definitive test that can be relied upon to predict allergic response in humans to a new protein; hence a composite approach to allergic response prediction is described in this study. The present study reports on the evaluation of the Cry proteins, encoded by cry1Ac, cry1Ab, cry2Ab, cry1Ca, cry1Fa/cry1Ca hybrid, being expressed in Bt food crops that are under field trials in India, for potential allergenic cross-reactivity using bioinformatics search tools. The sequence identity of amino acids was analyzed using FASTA3 of AllergenOnline version 10.0 and BLASTX of NCBI Entrez to identify any potential sequence matches to allergen proteins. As a step further in the detection of allergens, an independent database of domains in the allergens available in the AllergenOnline database was also developed. The results indicated no significant alignment and similarity of Cry proteins at domain level with any of the known allergens revealing that there is no potential risk of allergenic cross-reactivity. Copyright © 2010 Elsevier Ltd. All rights reserved.
BtoxDB: a comprehensive database of protein structural data on toxin-antitoxin systems.
Barbosa, Luiz Carlos Bertucci; Garrido, Saulo Santesso; Marchetto, Reinaldo
2015-03-01
Toxin-antitoxin (TA) systems are diverse and abundant genetic modules in prokaryotic cells that are typically formed by two genes encoding a stable toxin and a labile antitoxin. Because TA systems are able to repress growth or kill cells and are considered to be important actors in cell persistence (multidrug resistance without genetic change), these modules are considered potential targets for alternative drug design. In this scenario, structural information for the proteins in these systems is highly valuable. In this report, we describe the development of a web-based system, named BtoxDB, that stores all protein structural data on TA systems. The BtoxDB database was implemented as a MySQL relational database using PHP scripting language. Web interfaces were developed using HTML, CSS and JavaScript. The data were collected from the PDB, UniProt and Entrez databases. These data were appropriately filtered using specialized literature and our previous knowledge about toxin-antitoxin systems. The database provides three modules ("Search", "Browse" and "Statistics") that enable searches, acquisition of contents and access to statistical data. Direct links to matching external databases are also available. The compilation of all protein structural data on TA systems in one platform is highly useful for researchers interested in this content. BtoxDB is publicly available at http://www.gurupi.uft.edu.br/btoxdb. Copyright © 2015 Elsevier Ltd. All rights reserved.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-13
... Mining Company, a Subsidiary of Cliffs Natural Resources, Including On-Site Leased Workers From Vanhouse... Cliffs Natural Resources, Including On- Site Leased Workers From Vanhouse, Express Employment and Our... Natural Resources, including on-site leased workers from VanHouse and Express Employment, Silver Bay...
TCGA2BED: extracting, extending, integrating, and querying The Cancer Genome Atlas.
Cumbo, Fabio; Fiscon, Giulia; Ceri, Stefano; Masseroli, Marco; Weitschek, Emanuel
2017-01-03
Data extraction and integration methods are becoming essential to effectively access and take advantage of the huge amounts of heterogeneous genomics and clinical data increasingly available. In this work, we focus on The Cancer Genome Atlas, a comprehensive archive of tumoral data containing the results of high-throughout experiments, mainly Next Generation Sequencing, for more than 30 cancer types. We propose TCGA2BED a software tool to search and retrieve TCGA data, and convert them in the structured BED format for their seamless use and integration. Additionally, it supports the conversion in CSV, GTF, JSON, and XML standard formats. Furthermore, TCGA2BED extends TCGA data with information extracted from other genomic databases (i.e., NCBI Entrez Gene, HGNC, UCSC, and miRBase). We also provide and maintain an automatically updated data repository with publicly available Copy Number Variation, DNA-methylation, DNA-seq, miRNA-seq, and RNA-seq (V1,V2) experimental data of TCGA converted into the BED format, and their associated clinical and biospecimen meta data in attribute-value text format. The availability of the valuable TCGA data in BED format reduces the time spent in taking advantage of them: it is possible to efficiently and effectively deal with huge amounts of cancer genomic data integratively, and to search, retrieve and extend them with additional information. The BED format facilitates the investigators allowing several knowledge discovery analyses on all tumor types in TCGA with the final aim of understanding pathological mechanisms and aiding cancer treatments.
Automated Comparative Auditing of NCIT Genomic Roles Using NCBI
Cohen, Barry; Oren, Marc; Min, Hua; Perl, Yehoshua; Halper, Michael
2008-01-01
Biomedical research has identified many human genes and various knowledge about them. The National Cancer Institute Thesaurus (NCIT) represents such knowledge as concepts and roles (relationships). Due to the rapid advances in this field, it is to be expected that the NCIT’s Gene hierarchy will contain role errors. A comparative methodology to audit the Gene hierarchy with the use of the National Center for Biotechnology Information’s (NCBI’s) Entrez Gene database is presented. The two knowledge sources are accessed via a pair of Web crawlers to ensure up-to-date data. Our algorithms then compare the knowledge gathered from each, identify discrepancies that represent probable errors, and suggest corrective actions. The primary focus is on two kinds of gene-roles: (1) the chromosomal locations of genes, and (2) the biological processes in which genes plays a role. Regarding chromosomal locations, the discrepancies revealed are striking and systematic, suggesting a structurally common origin. In regard to the biological processes, difficulties arise because genes frequently play roles in multiple processes, and processes may have many designations (such as synonymous terms). Our algorithms make use of the roles defined in the NCIT Biological Process hierarchy to uncover many probable gene-role errors in the NCIT. These results show that automated comparative auditing is a promising technique that can identify a large number of probable errors and corrections for them in a terminological genomic knowledge repository, thus facilitating its overall maintenance. PMID:18486558
Several problems in regard to national land management
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dong Wenlang
1983-09-21
This article examines several problems with regard to land management in China. National land management is defined as development of the territorial land (including the earth's surface and underground), territorial waters and territorial air space under the jurisdiction of a sovereign country. The Chinese State Council established the Bureau of National Land Management in 1981. Areas of concern include natural resources, or land resources (including continental land, rivers and lakes, territorial waters and what is beneath the waters and the airspace above the waters, also the continental shelves), mineral resources and biological resources; social resources, which include human resources, intellectualmore » resources, social and cultural traditions, and the material and technical foundations of a society. Untapped resources of land, waters, forests, grasslands and minerals are to be developed through reclamation, mining, and engineering projects. Geography and national land economics are the theoretical and applied sciences directly related to national land management.« less
Sustaining flows of crucial watershed resources
J. E. de Steiguer
2000-01-01
Watersheds are the source of a number of resources which are of benefit to society. These resources include water, timber, grazing, recreation, wildlife and others, often described as multiple-use resources. In addition, however, watersheds also produce a number of less tangible resources and uses, which are also socially important. These include amenity, option values...
Low-Temperature Hydrothermal Resource Potential
Katherine Young
2016-06-30
Compilation of data (spreadsheet and shapefiles) for several low-temperature resource types, including isolated springs and wells, delineated area convection systems, sedimentary basins and coastal plains sedimentary systems. For each system, we include estimates of the accessible resource base, mean extractable resource and beneficial heat. Data compiled from USGS and other sources. The paper (submitted to GRC 2016) describing the methodology and analysis is also included.
Low-Temperature Hydrothermal Resource Potential Estimate
Katherine Young
2016-06-30
Compilation of data (spreadsheet and shapefiles) for several low-temperature resource types, including isolated springs and wells, delineated area convection systems, sedimentary basins and coastal plains sedimentary systems. For each system, we include estimates of the accessible resource base, mean extractable resource and beneficial heat. Data compiled from USGS and other sources. The paper (submitted to GRC 2016) describing the methodology and analysis is also included.
Code of Federal Regulations, 2011 CFR
2011-01-01
..., scenic and aesthetic enjoyment, and resource creation or restoration projects. Natural resources include.... Biological and physical resources include, but are not limited to, air, tidal and nontidal wetlands, ocean...
Code of Federal Regulations, 2010 CFR
2010-01-01
..., scenic and aesthetic enjoyment, and resource creation or restoration projects. Natural resources include.... Biological and physical resources include, but are not limited to, air, tidal and nontidal wetlands, ocean...
Kim, Sun; Chatr-aryamontri, Andrew; Chang, Christie S.; Oughtred, Rose; Rust, Jennifer; Wilbur, W. John; Comeau, Donald C.; Dolinski, Kara; Tyers, Mike
2017-01-01
A great deal of information on the molecular genetics and biochemistry of model organisms has been reported in the scientific literature. However, this data is typically described in free text form and is not readily amenable to computational analyses. To this end, the BioGRID database systematically curates the biomedical literature for genetic and protein interaction data. This data is provided in a standardized computationally tractable format and includes structured annotation of experimental evidence. BioGRID curation necessarily involves substantial human effort by expert curators who must read each publication to extract the relevant information. Computational text-mining methods offer the potential to augment and accelerate manual curation. To facilitate the development of practical text-mining strategies, a new challenge was organized in BioCreative V for the BioC task, the collaborative Biocurator Assistant Task. This was a non-competitive, cooperative task in which the participants worked together to build BioC-compatible modules into an integrated pipeline to assist BioGRID curators. As an integral part of this task, a test collection of full text articles was developed that contained both biological entity annotations (gene/protein and organism/species) and molecular interaction annotations (protein–protein and genetic interactions (PPIs and GIs)). This collection, which we call the BioC-BioGRID corpus, was annotated by four BioGRID curators over three rounds of annotation and contains 120 full text articles curated in a dataset representing two major model organisms, namely budding yeast and human. The BioC-BioGRID corpus contains annotations for 6409 mentions of genes and their Entrez Gene IDs, 186 mentions of organism names and their NCBI Taxonomy IDs, 1867 mentions of PPIs and 701 annotations of PPI experimental evidence statements, 856 mentions of GIs and 399 annotations of GI evidence statements. The purpose, characteristics and possible future uses of the BioC-BioGRID corpus are detailed in this report. Database URL: http://bioc.sourceforge.net/BioC-BioGRID.html PMID:28077563
HypoxiaDB: a database of hypoxia-regulated proteins
Khurana, Pankaj; Sugadev, Ragumani; Jain, Jaspreet; Singh, Shashi Bala
2013-01-01
There has been intense interest in the cellular response to hypoxia, and a large number of differentially expressed proteins have been identified through various high-throughput experiments. These valuable data are scattered, and there have been no systematic attempts to document the various proteins regulated by hypoxia. Compilation, curation and annotation of these data are important in deciphering their role in hypoxia and hypoxia-related disorders. Therefore, we have compiled HypoxiaDB, a database of hypoxia-regulated proteins. It is a comprehensive, manually-curated, non-redundant catalog of proteins whose expressions are shown experimentally to be altered at different levels and durations of hypoxia. The database currently contains 72 000 manually curated entries taken on 3500 proteins extracted from 73 peer-reviewed publications selected from PubMed. HypoxiaDB is distinctive from other generalized databases: (i) it compiles tissue-specific protein expression changes under different levels and duration of hypoxia. Also, it provides manually curated literature references to support the inclusion of the protein in the database and establish its association with hypoxia. (ii) For each protein, HypoxiaDB integrates data on gene ontology, KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway, protein–protein interactions, protein family (Pfam), OMIM (Online Mendelian Inheritance in Man), PDB (Protein Data Bank) structures and homology to other sequenced genomes. (iii) It also provides pre-compiled information on hypoxia-proteins, which otherwise requires tedious computational analysis. This includes information like chromosomal location, identifiers like Entrez, HGNC, Unigene, Uniprot, Ensembl, Vega, GI numbers and Genbank accession numbers associated with the protein. These are further cross-linked to respective public databases augmenting HypoxiaDB to the external repositories. (iv) In addition, HypoxiaDB provides an online sequence-similarity search tool for users to compare their protein sequences with HypoxiaDB protein database. We hope that HypoxiaDB will enrich our knowledge about hypoxia-related biology and eventually will lead to the development of novel hypothesis and advancements in diagnostic and therapeutic activities. HypoxiaDB is freely accessible for academic and non-profit users via http://www.hypoxiadb.com. Database URL: http://www.hypoxiadb.com PMID:24178989
40 CFR 300.600 - Designation of federal trustees.
Code of Federal Regulations, 2014 CFR
2014-07-01
... resources, including their supporting ecosystems. They are authorized to act pursuant to section 107(f) of..., loss of, or threat to natural resources, including their supporting ecosystems, as a result of a... following natural resources and their supporting ecosystems: marine fishery resources; anadromous fish...
40 CFR 300.600 - Designation of federal trustees.
Code of Federal Regulations, 2013 CFR
2013-07-01
... resources, including their supporting ecosystems. They are authorized to act pursuant to section 107(f) of..., loss of, or threat to natural resources, including their supporting ecosystems, as a result of a... following natural resources and their supporting ecosystems: marine fishery resources; anadromous fish...
40 CFR 300.600 - Designation of federal trustees.
Code of Federal Regulations, 2012 CFR
2012-07-01
... resources, including their supporting ecosystems. They are authorized to act pursuant to section 107(f) of..., loss of, or threat to natural resources, including their supporting ecosystems, as a result of a... following natural resources and their supporting ecosystems: marine fishery resources; anadromous fish...
40 CFR 300.600 - Designation of federal trustees.
Code of Federal Regulations, 2011 CFR
2011-07-01
... resources, including their supporting ecosystems. They are authorized to act pursuant to section 107(f) of..., loss of, or threat to natural resources, including their supporting ecosystems, as a result of a... following natural resources and their supporting ecosystems: marine fishery resources; anadromous fish...
Prioritizing High-Temperature Geothermal Resources in Utah
Blackett, R.E.; Brill, T.C.; Sowards, G.M.
2002-01-01
The Utah Geological Survey and the Utah Energy Office recently released geothermal resource information for Utah as a "digital atlas." We are now expanding this project to include economic analyses of selected geothermal sites and previously unavailable resource information. The enhancements to the digital atlas will include new resource, demographic, regulatory, economic, and other information to allow analyses of economic factors for comparing and ranking geothermal resource sites in Utah for potential electric power development. New resource information includes temperature gradient and fluid chemistry data, which was previously proprietary. Economic analyses are based upon a project evaluation model to assess capital and operating expenses for a variety of geothermal powerplant configuration scenarios. A review of legal and institutional issues regarding geothermal development coupled with water development will also be included.
76 FR 30393 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-25
...-W-74,530 Hewlett Packard Company Human Resources Division Including Workers Whose Unemployment... California TA-W-74,530A Hewlett Packard Company Human Resources Division Including Workers Whose Unemployment... Packard Company Human Resources Division Including Workers Whose Unemployment Insurance (UI) Wages Are...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-29
... Action also includes the development of a 300-room hotel, casino, restaurants, retail establishments, a... addressed within the FEIS included land resources, water resources, air quality, biological resources..., Chief of the Division of Environmental, Cultural Resources Management and Safety, at the address listed...
Focus on Firearms. Biblio Alert! New Resources for Preventing Injury and Violence.
ERIC Educational Resources Information Center
National Center for Education in Maternal and Child Health, Arlington, VA.
This annotated bibliography provides information on important resources on firearm injuries. It is divided into two sections: (1) New Resources, including journal articles (28 titles), reports and books (15 titles), other resources (13 titles), and popular press (3 titles); and (2) Classics, including journal articles (10 titles), reports and…
NASA Earth Resources Survey Symposium. Volume 1-B: Geology, Information Systems and Services
NASA Technical Reports Server (NTRS)
1975-01-01
A symposium was conducted on the practical applications of earth resources survey technology including utilization and results of data from programs involving LANDSAT, the Skylab earth resources experiment package, and aircraft. Topics discussed include geological structure, landform surveys, energy and extractive resources, and information systems and services.
76 FR 3831 - Crew Resource Management Training for Crewmembers in Part 135 Operations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-21
... training in the use of crew resource management principles, as appropriate for their operation. This final...; Amendment No.: 135-122] RIN 2120-AJ32 Crew Resource Management Training for Crewmembers in Part 135... include in their training programs crew resource management training for crewmembers, including pilots and...
Resource Recovery. Redefining the 3 Rs. Reduce...Reuse...Recycle. Resources in Technology.
ERIC Educational Resources Information Center
Technology Teacher, 1991
1991-01-01
Discusses the problems of waste disposal, recycling, and resource recovery. Includes information on the social and cultural impact, the three classes of resource recovery (reuse, direct recycling, and indirect recycling), and specific products (paper, glass, plastics, metals, and so on). Includes a student quiz and possible outcomes. (JOW)
Goh, Elaine Suk-Ying; Li, Chumei; Horsburgh, Sheri; Kasai, Yumi; Kolomietz, Elena; Morel, Chantal France
2010-02-01
Roberts syndrome (RBS) (OMIM #268300) is a rare autosomal recessive disorder characterized by tetraphocomelia (symmetrical limb reduction), craniofacial anomalies, growth retardation, mental retardation, cardiac and renal abnormalities. The syndrome is caused by mutations in the ESCO2 (establishment of cohesion 1 homolog 2) (Entrez 609353) gene, which is located at 8p21.1, and encodes a protein essential in establishing sister chromatid cohesion during S phase. SC phocomelia (SC) (OMIM #269000), has less severe symmetric limb reduction, flexion contractures of various joints, minor facial anomalies, growth retardation and occasionally, mental retardation. These two syndromes can be considered part of a spectrum, with RBS at the most severe range in which severely affected infants may be stillborn or die in the post-natal period, while individuals with SC phocomelia represent the milder end of the spectrum and typically survive to adulthood. In both presentations, karyotype investigations characteristically reveal premature centromere separation (PCS), otherwise known as heterochromatin repulsion or puffing. There is little literature about the follow-up of adults with the spectrum of RBS/SC phocomelia or their recommended management. We report on an adult presentation of RBS/SC phocomelia spectrum disorder with a history of major cardiac malformation in childhood, normal limbs on physical examination, mild facial anomalies, mild learning difficulties, and PCS. Molecular studies of ESCO2 have confirmed the diagnosis. A literature review, focussing on adult manifestations of this condition and a discussion of follow-up guidelines are presented. Copyright 2010 Wiley-Liss, Inc.
ERIC Educational Resources Information Center
Web Feet K-8, 2001
2001-01-01
This annotated subject guide to Web sites and additional resources focuses on biomes. Specifies age levels for resources that include Web sites, CD-ROMs and software, videos, books, audios, and magazines; includes professional resources; and presents a relevant class activity. (LRW)
Energy and Environment Guide to Action - Chapter 7.1: Electricity Resource Planning and Procurement
Electricity resource planning includes power plants, electricity delivery, and end-use demand. Find more information on designing, implementing, and evaluating electricity resource planning policies. State success stories are included for reference.
A Guide to Internet Resources in Language Arts.
ERIC Educational Resources Information Center
Homme, John, Comp.; And Others
This paper presents a list of 154 Internet resources (listservs, freenets, telnet sites, gophers, etc.) dealing with language arts. Each entry in the list includes the name of the resource, and subscription and electronic mail addresses. Some of the entries in the list include a brief description of the resource. The paper lists 17 language arts…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Siegel, S.M.; Siegel, B.Z.
1980-06-01
The environmental consequences of natural processes in a volcanic-fumerolic region and of geothermal resource development are presented. These include acute ecological effects, toxic gas emissions during non-eruptive periods, the HGP-A geothermal well as a site-specific model, and the geothermal resources potential of Hawaii. (MHR)
43 CFR 3809.401 - Where do I file my plan of operations and what information must I include with it?
Code of Federal Regulations, 2012 CFR
2012-10-01
... equipment, devices, or practices you propose to use during operations including, where applicable— (i) Maps..., paleontological resources, cave resources, hydrology, soils, vegetation, wildlife, air quality, cultural resources...
43 CFR 3809.401 - Where do I file my plan of operations and what information must I include with it?
Code of Federal Regulations, 2014 CFR
2014-10-01
... equipment, devices, or practices you propose to use during operations including, where applicable— (i) Maps..., paleontological resources, cave resources, hydrology, soils, vegetation, wildlife, air quality, cultural resources...
43 CFR 3809.401 - Where do I file my plan of operations and what information must I include with it?
Code of Federal Regulations, 2013 CFR
2013-10-01
... equipment, devices, or practices you propose to use during operations including, where applicable— (i) Maps..., paleontological resources, cave resources, hydrology, soils, vegetation, wildlife, air quality, cultural resources...
Ellis, Margaret S.; Gunther, Gregory L.; Flores, Romeo M.; Stricker, Gary D.; Ochs, Allan M.; Schuenemeyer, John H.
1998-01-01
The National Coal Resource Assessment of the Wyodak-Anderson coal zone includes reports on the geology, stratigraphy, quality, and quantity of coal. The calculation of resources is only one aspect of the assessment. Without thorough documentation of the coal resource study and the methods used, the results of our study could be misinterpreted. The task of calculating coal resources included many steps, the use of several commercial software programs, and the incorporation of custom programs. The methods used for calculating coal resources for the Wyodak-Anderson coal zone vary slightly from the methods used in other study areas, and by other workers in the National Coal Resource Assessment. The Wyodak-Anderson coal zone includes up to 10 coal beds in any given location. The net coal thickness of the zone at each data point location was calculated by summing the thickness of all of the coal beds that were greater than 2.5 ft thick. The amount of interburden is not addressed or reported in this coal resource assessment. The amount of overburden reported is the amount of rock above the stratigraphically highest coal bed in the zone. The resource numbers reported do not include coal within mine or lease areas, in areas containing mapped Wyodak-Anderson clinker, or in areas where the coal is extrapolated to be less than 2.5 ft thick. The resources of the Wyodak-Anderson coal zone are reported in Ellis and others (1998). A general description of how the resources were calculated is included in that report. The purpose of this report is to document in more detail some of the parameters and methods used, define our spatial data, compare resources calculated using different grid options and calculation methods, and explain the application of confidence limits to the resource calculation.
Crooks, Rachel E; Bell, Meaghan; Patten, Scott B; Wiebe, Samuel; Holroyd-Leduc, Jayna; Bulloch, Andrew G; Macrodimitris, Sophia; Mackie, Aaron; Sauro, Khara M; Federico, Paolo; Jetté, Nathalie
2017-05-01
Depression is common in epilepsy, and is often under-detected and under-treated. The motivation to create a depression eHub for persons with epilepsy is to connect them to the best available online resources to effectively manage their depression. The study sought to: 1) identify facilitators and barriers to accessing resources related to management of epilepsy and/or depression and 2) discuss gaps in available resources (free and in the public domain) and 3) identify suggestions for future content. Semi-structured interviews were conducted with ten patients with epilepsy and a history of depression. Using inductive analysis, two team members engaged in a process of textual open-coding utilizing a conventional content analysis approach whereby content was conceptually clustered based on the research questions. A phenomenological framework was applied to describe the phenomenon of online health resource access and utilization from the perspective of people with epilepsy. Facilitators to the use of online resources included information credibility, thoughtful organization, and accessibility of resources. Barriers included difficulties finding and piecing together information from many different sites. Patients reported difficulty having the motivation to seek out resources while depressed, which was compounded by feelings of stigma, social isolation, and lack of control. Gaps in resources included a lack of information about living with epilepsy day-to-day and resources for family and friends. Suggested content included information to raise awareness about epilepsy and depression; questionnaires to screen for symptoms of depression; stories of other patients with epilepsy and depression via video or moderated forums; current research and news; local community resources; and tools and strategies to manage depression in epilepsy. There is a gap in accessible resources for patients with epilepsy and depression as well as barriers that include epilepsy-related restrictions, depression-related impairments, lack of awareness, and stigmatization. These results should be used to guide the development of e-Health resources for patients with epilepsy. Copyright © 2017 Elsevier Inc. All rights reserved.
Idaho National Laboratory Cultural Resource Monitoring Report for FY 2010
DOE Office of Scientific and Technical Information (OSTI.GOV)
INL Cultural Resource Management Office
2010-10-01
This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during fiscal year 2010 (FY 2010). Throughout the year, thirty-three cultural resource localities were revisited, including somethat were visited more than once, including: two locations with Native American human remains, one of which is a cave, two additional caves, twenty-six prehistoric archaeological sites, two historic stage stations, and Experimental Breeder Reactor-I, which is a designated National Historic Landmark. The resources that were monitored included seventeen that are routinely visited and sixteen that are located in INL project areas. Although impacts weremore » documented at a few locations and one trespassing incident (albeit sans formal charges) was discovered, no significant adverse effects that would threaten the National Register eligibility of any resources were observed. Monitoring also demonstrated that several INL projects generally remain in compliance with recommendations to protect cultural resources.« less
[Perilla resources of China and essential oil chemotypes of Perilla leaves].
Wei, Chang-Ling; Guo, Bao-Lin; Zhang, Chen-Wu; Zhang, Fen; Tian, Jing; Bai, Xiao-Lin; Zhang, Shun-Nan
2016-05-01
This study, based on the findings for Perilla resources, aimed to describe the species, distribution, importance, features, utilization and status of quantitative Perilla resources in China. This not only helps people to know well about the existing resources and researching development, but also indicates the overall distribution, selection and rational use of Perilla resource in the future. According to the output types, Perilla resources are divided into two categories: wild resources and cultivated resources; and based on its common uses, the cultivated resources are further divided into medicine resources, seed-used resources and export resources. The distribution areas of wild resources include Henan, Sichuan, Anhui, Jiangxi, Guangxi, Hunan, Jiangsu and Zhejiang. The distribution areas of medicine resources are concentrated in Hebei, Anhui, Chongqing, Guangxi and Guangdong. Seed-used resources are mainly distributed in Gansu, Heilongjiang, Jilin, Chongqing and Yunnan. Export resource areas are mainly concentrated in coastal cities, such as Zhejiang, Jiangsu, Shandong and Zhejiang. For the further study, the essential oil of leaf samples from different areas were extracted by the steam distillation method and analyzed by GC-MS. The differences in essential oil chemotypes among different Perilla leaves were compared by analyzing their chemical constituents. The main 31 constituents of all samples included: perillaketone (0.93%-96.55%), perillaldehyde (0.10%-61.24%), perillene (52.15%), caryophyllene (3.22%-26.67%), and α-farnesene (2.10%-21.54%). These samples can be classified into following five chemotypes based on the synthesis pathways: PK-type, PA-type, PL-type, PP-type and EK-type. The chemotypes of wild resources included PK-type and PA-type, with PK-type as the majority. All of the five chemotypes are included in cultivated resources, with PA-type as the majority. Seed-used resources are all PK-type, and export resources are all PA-type. The P. frutescens var. frutescens include five chemotypes, with PK-type as the majority. The PK-type leaves of P. frutescens var. acuta are green, while the PA-type leaves are reddish purple. The P. fruteseens var. crispa was mainly PA type with reddish purple leaves. The differences of the main chemotypes provide a scientific basis for distinguishing between Zisu and Baisu in previous literatures. Based on the lung toxicity of PK and the traditional use of Perilla, the testing standard of essential oil and Perilla herb shall be built, and PA type is recommended to be used in traditional Chinese medicine. Copyright© by the Chinese Pharmaceutical Association.
[Current status and prospects of traditional Chinese medicine resource ex-situ conservation].
Que, Ling; Yang, Guang; Miao, Jian-Hua; Wang, Hai-Yang; Chen, Min; Zang, Chun-Xin
2016-10-01
Protection of traditional Chinese medicine (TCM) resources is the foundation of sustainable development of TCM industry, which includes the in-situ and ex-situ conservation. The development of TCM resource ex-situ conservation was reviewed, and hotpots in the conservation and its development practices were analyzed. Therefore national TCM resource ex-situ conservation systems were proposed, including the establishment of TCM resources introduction gardens, TCM resource in vitro conservation library and TCM resource bio-information sharing platform, rational distribution of TCM resources ex-situ conservation agencies, along with the advancement of TCM varieties breeding, and the perfection of Chinese herbal medicines seed and seedlings market, which are of significant importance on the guidance of TCM resource ex-situ conservation development. Copyright© by the Chinese Pharmaceutical Association.
Performance-Based Assessment Resource Guide.
ERIC Educational Resources Information Center
Gilbert, Judith C.; Burger, Patricia
This resource guide reviews a variety of performance-based student assessment strategies, and provides examples of, and references for, the strategies. Strategies include anecdotal records, interviews, peer report and group evaluations, and portfolios. Materials in the guide include: (1) a resource guide update form for teachers; (2) department…
43 CFR 11.31 - What does the Assessment Plan include?
Code of Federal Regulations, 2011 CFR
2011-10-01
....31 Section 11.31 Public Lands: Interior Office of the Secretary of the Interior NATURAL RESOURCE.... The Assessment Plan shall include descriptions of the natural resources and the geographical areas... co-trusteeship, for those natural resources considered within the Assessment Plan. The authorized...
7 CFR 2.20 - Under Secretary for Natural Resources and Environment.
Code of Federal Regulations, 2012 CFR
2012-01-01
... cooperated in shall include, but not be limited to: renewable resource management research, renewable resource environmental research; renewable resource protection research; renewable resource utilization research, and renewable resource assessment research (16 U.S.C. 1641-1647). (x) Use authorities and means...
7 CFR 2.20 - Under Secretary for Natural Resources and Environment.
Code of Federal Regulations, 2011 CFR
2011-01-01
... cooperated in shall include, but not be limited to: renewable resource management research, renewable resource environmental research; renewable resource protection research; renewable resource utilization research, and renewable resource assessment research (16 U.S.C. 1641-1647). (x) Use authorities and means...
A Resource Curriculum in Public Address.
ERIC Educational Resources Information Center
Bergman, Richard F.
Developed as part of a series of teacher resource curriculum units in communication arts, this resource unit on public speaking includes several components organized for direct teacher use. The seven units that are offered include introduction to public communication, delivery, language, organization, speaking to share information, speaking to…
Ozyurt, Ibrahim Burak; Grethe, Jeffrey S; Martone, Maryann E; Bandrowski, Anita E
2016-01-01
The NIF Registry developed and maintained by the Neuroscience Information Framework is a cooperative project aimed at cataloging research resources, e.g., software tools, databases and tissue banks, funded largely by governments and available as tools to research scientists. Although originally conceived for neuroscience, the NIF Registry has over the years broadened in the scope to include research resources of general relevance to biomedical research. The current number of research resources listed by the Registry numbers over 13K. The broadening in scope to biomedical science led us to re-christen the NIF Registry platform as SciCrunch. The NIF/SciCrunch Registry has been cataloging the resource landscape since 2006; as such, it serves as a valuable dataset for tracking the breadth, fate and utilization of these resources. Our experience shows research resources like databases are dynamic objects, that can change location and scope over time. Although each record is entered manually and human-curated, the current size of the registry requires tools that can aid in curation efforts to keep content up to date, including when and where such resources are used. To address this challenge, we have developed an open source tool suite, collectively termed RDW: Resource Disambiguator for the (Web). RDW is designed to help in the upkeep and curation of the registry as well as in enhancing the content of the registry by automated extraction of resource candidates from the literature. The RDW toolkit includes a URL extractor from papers, resource candidate screen, resource URL change tracker, resource content change tracker. Curators access these tools via a web based user interface. Several strategies are used to optimize these tools, including supervised and unsupervised learning algorithms as well as statistical text analysis. The complete tool suite is used to enhance and maintain the resource registry as well as track the usage of individual resources through an innovative literature citation index honed for research resources. Here we present an overview of the Registry and show how the RDW tools are used in curation and usage tracking.
Ozyurt, Ibrahim Burak; Grethe, Jeffrey S.; Martone, Maryann E.; Bandrowski, Anita E.
2016-01-01
The NIF Registry developed and maintained by the Neuroscience Information Framework is a cooperative project aimed at cataloging research resources, e.g., software tools, databases and tissue banks, funded largely by governments and available as tools to research scientists. Although originally conceived for neuroscience, the NIF Registry has over the years broadened in the scope to include research resources of general relevance to biomedical research. The current number of research resources listed by the Registry numbers over 13K. The broadening in scope to biomedical science led us to re-christen the NIF Registry platform as SciCrunch. The NIF/SciCrunch Registry has been cataloging the resource landscape since 2006; as such, it serves as a valuable dataset for tracking the breadth, fate and utilization of these resources. Our experience shows research resources like databases are dynamic objects, that can change location and scope over time. Although each record is entered manually and human-curated, the current size of the registry requires tools that can aid in curation efforts to keep content up to date, including when and where such resources are used. To address this challenge, we have developed an open source tool suite, collectively termed RDW: Resource Disambiguator for the (Web). RDW is designed to help in the upkeep and curation of the registry as well as in enhancing the content of the registry by automated extraction of resource candidates from the literature. The RDW toolkit includes a URL extractor from papers, resource candidate screen, resource URL change tracker, resource content change tracker. Curators access these tools via a web based user interface. Several strategies are used to optimize these tools, including supervised and unsupervised learning algorithms as well as statistical text analysis. The complete tool suite is used to enhance and maintain the resource registry as well as track the usage of individual resources through an innovative literature citation index honed for research resources. Here we present an overview of the Registry and show how the RDW tools are used in curation and usage tracking. PMID:26730820
Educational Equity Options. A Resource Bibliography.
ERIC Educational Resources Information Center
Martino, Susan; Watson, Jennifer
This selected list of educational resources includes 44 video items, 23 books, 9 posters, and 24 educational equity organizations and resource centers. Video materials and books are classified according to appropriate age groups and student abilities. All items are annotated. Topics of the videos and books include career choices, special needs…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-17
... Health Care and Advantage Technical Resourcing, Saginaw, MI; Amended Certification Regarding Eligibility... on-site leased workers from Advantage Technical Resourcing were employed on-site at the Saginaw... Department is amending this certification to include workers leased from Advantage Technical Resourcing...
P. J. Ince
2004-01-01
In economics, primary inputs or factors of production define the term âresources.â Resources include land resources (plants, animals, and minerals), labor, capital, and entrepreneurship. Almost all pulp and paper fiber resources are plant materials obtained from trees or agricultural crops. These resources encompass plant materials harvested directly from the land (...
Controlling user access to electronic resources without password
Smith, Fred Hewitt
2015-06-16
Described herein are devices and techniques for remotely controlling user access to a restricted computer resource. The process includes pre-determining an association of the restricted computer resource and computer-resource-proximal environmental information. Indicia of user-proximal environmental information are received from a user requesting access to the restricted computer resource. Received indicia of user-proximal environmental information are compared to associated computer-resource-proximal environmental information. User access to the restricted computer resource is selectively granted responsive to a favorable comparison in which the user-proximal environmental information is sufficiently similar to the computer-resource proximal environmental information. In at least some embodiments, the process further includes comparing user-supplied biometric measure and comparing it with a predetermined association of at least one biometric measure of an authorized user. Access to the restricted computer resource is granted in response to a favorable comparison.
Resource Aware Intelligent Network Services (RAINS) Final Technical Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lehman, Tom; Yang, Xi
The Resource Aware Intelligent Network Services (RAINS) project conducted research and developed technologies in the area of cyber infrastructure resource modeling and computation. The goal of this work was to provide a foundation to enable intelligent, software defined services which spanned the network AND the resources which connect to the network. A Multi-Resource Service Plane (MRSP) was defined, which allows resource owners/managers to locate and place themselves from a topology and service availability perspective within the dynamic networked cyberinfrastructure ecosystem. The MRSP enables the presentation of integrated topology views and computation results which can include resources across the spectrum ofmore » compute, storage, and networks. The RAINS project developed MSRP includes the following key components: i) Multi-Resource Service (MRS) Ontology/Multi-Resource Markup Language (MRML), ii) Resource Computation Engine (RCE), iii) Modular Driver Framework (to allow integration of a variety of external resources). The MRS/MRML is a general and extensible modeling framework that allows for resource owners to model, or describe, a wide variety of resource types. All resources are described using three categories of elements: Resources, Services, and Relationships between the elements. This modeling framework defines a common method for the transformation of cyber infrastructure resources into data in the form of MRML models. In order to realize this infrastructure datification, the RAINS project developed a model based computation system, i.e. “RAINS Computation Engine (RCE)”. The RCE has the ability to ingest, process, integrate, and compute based on automatically generated MRML models. The RCE interacts with the resources thru system drivers which are specific to the type of external network or resource controller. The RAINS project developed a modular and pluggable driver system which facilities a variety of resource controllers to automatically generate, maintain, and distribute MRML based resource descriptions. Once all of the resource topologies are absorbed by the RCE, a connected graph of the full distributed system topology is constructed, which forms the basis for computation and workflow processing. The RCE includes a Modular Computation Element (MCE) framework which allows for tailoring of the computation process to the specific set of resources under control, and the services desired. The input and output of an MCE are both model data based on MRS/MRML ontology and schema. Some of the RAINS project accomplishments include: Development of general and extensible multi-resource modeling framework; Design of a Resource Computation Engine (RCE) system which includes the following key capabilities; Absorb a variety of multi-resource model types and build integrated models; Novel architecture which uses model based communications across the full stack for all Flexible provision of abstract or intent based user facing interfaces; Workflow processing based on model descriptions; Release of the RCE as an open source software; Deployment of RCE in the University of Maryland/Mid-Atlantic Crossroad ScienceDMZ in prototype mode with a plan under way to transition to production; Deployment at the Argonne National Laboratory DTN Facility in prototype mode; Selection of RCE by the DOE SENSE (SDN for End-to-end Networked Science at the Exascale) project as the basis for their orchestration service.« less
Recommended Resources for Planning to Evaluate Program Improvement Efforts (Including the SSIP)
ERIC Educational Resources Information Center
National Center for Systemic Improvement at WestEd, 2015
2015-01-01
This document provides a list of recommended existing resources for state Part C and Part B 619 staff and technical assistance (TA) providers to utilize to support evaluation planning for program improvement efforts (including the State Systemic Improvement Plan, SSIP). There are many resources available related to evaluation and evaluation…
ERIC Educational Resources Information Center
Dissemination and Assessment Center for Bilingual Education, Austin, TX.
This resource guide is designed as an aid to primary teachers of Mexican-American children. Besides including basic introductory material, the volume provides suggestions for parent involvement, classroom learning activity centers, and extensive resource materials. Classroom learning activity centers include: Art, Book, Communication, Discussion,…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-29
... license to include inter alia conditions for fish passage facilities and authorization to construct the... originally opposed Tacoma's Cultural Resource Summary Report, and cultural resource protection became a... in the MOA. The MOA includes a Treatment Plan that Tacoma must follow to protect cultural resources...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-05
... FERC Online service, please e-mail [email protected] . or call (866) 208-3676 (toll free). For... Resources, Inc.; Supplemental Notice That Initial Market-Based Rate Filing Includes Request For Blanket... proceeding of DPL Energy Resources, Inc.'s application for market-based rate authority, with an accompanying...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-23
... Harvard Resources Solutions, Lebanon, VA; Amended Certification Regarding Eligibility To Apply for Worker..., including on-site leased workers from At- Work Personnel and CJR Solutions, d/b/a Harvard Resources... from At-Work Personnel and CJR Solutions, d/b/a Harvard Resource Solutions, Lebanon, Virginia, who...
How To Develop a Resource Center for a Career Education Program.
ERIC Educational Resources Information Center
Eversole, Opal
Intended to guide local school systems in the development of a resource center for a career education program, this booklet identifies three kinds of resources which should be included: Human resources, community resources, and material resources. Then in a question/answer format, the guide explains the basic steps in identifying all resources…
Bibliography on Multicultural Activities in the Classroom: A Listing of Resources.
ERIC Educational Resources Information Center
Brady, Mary Lou; Geile, Carole
This bibliography contains information on multicultural activities in the classroom. It is divided into three sections: a list of 97 book resources, a list of 59 journal articles, and a list of 17 ERIC (Educational Resources Information Center) resources. The resources include general multicultural teaching guides and specific topical resources:…
Code of Federal Regulations, 2010 CFR
2010-01-01
... values. Living resources include natural and cultured plant life, fish, shellfish, marine mammals, and..., Great Lakes, and coastal resources means any discipline or field (including marine sciences and the physical, natural, and biological sciences, and engineering, included therein, marine technology, education...
Code of Federal Regulations, 2013 CFR
2013-01-01
... values. Living resources include natural and cultured plant life, fish, shellfish, marine mammals, and..., Great Lakes, and coastal resources means any discipline or field (including marine sciences and the physical, natural, and biological sciences, and engineering, included therein, marine technology, education...
Code of Federal Regulations, 2011 CFR
2011-01-01
... values. Living resources include natural and cultured plant life, fish, shellfish, marine mammals, and..., Great Lakes, and coastal resources means any discipline or field (including marine sciences and the physical, natural, and biological sciences, and engineering, included therein, marine technology, education...
Code of Federal Regulations, 2014 CFR
2014-01-01
... values. Living resources include natural and cultured plant life, fish, shellfish, marine mammals, and..., Great Lakes, and coastal resources means any discipline or field (including marine sciences and the physical, natural, and biological sciences, and engineering, included therein, marine technology, education...
Code of Federal Regulations, 2012 CFR
2012-01-01
... values. Living resources include natural and cultured plant life, fish, shellfish, marine mammals, and..., Great Lakes, and coastal resources means any discipline or field (including marine sciences and the physical, natural, and biological sciences, and engineering, included therein, marine technology, education...
Corbould, A
2008-10-01
Hyperinsulinemia as a consequence of insulin resistance causes hyperandrogenemia in women. The objective was to review evidence for the converse situation, i.e. whether androgens adversely influence insulin action. Androgen excess could potentially contribute to the pathogenesis of insulin resistance in women with polycystic ovary syndrome (PCOS), metabolic syndrome/type 2 diabetes, and in obese peripubertal girls. An Entrez-PubMed search was conducted to identify studies addressing the relationship of androgens with metabolic syndrome/type 2 diabetes in women. Studies reporting outcomes of androgen administration, interventions to reduce androgen effects in hyperandrogenemic women, and basic studies investigating androgen effects on insulin target tissues were reviewed. Multiple studies showed associations between serum testosterone and insulin resistance or metabolic syndrome/type 2 diabetes risk in women, but their cross-sectional nature did not allow conclusions about causality. Androgen administration to healthy women was associated with development of insulin resistance. Intervention studies in women with hyperandrogenism were limited by small subject numbers and use of indirect methods for assessing insulin sensitivity. However, in three of the seven studies using euglycemic hyperinsulinemic clamps, reduction of androgen levels or blockade of androgen action improved insulin sensitivity. Testosterone administration to female rats caused skeletal muscle insulin resistance. Testosterone induced insulin resistance in adipocytes of women in vitro. In conclusion, the metabolic consequences of androgen excess in women have been under-researched. Studies of long-term interventions that lower androgen levels or block androgen effects in young women with hyperandrogenism are needed to determine whether these might protect against metabolic syndrome/type 2 diabetes in later life. Copyright (c) 2008 John Wiley & Sons, Ltd.
Functional cohesion of gene sets determined by latent semantic indexing of PubMed abstracts.
Xu, Lijing; Furlotte, Nicholas; Lin, Yunyue; Heinrich, Kevin; Berry, Michael W; George, Ebenezer O; Homayouni, Ramin
2011-04-14
High-throughput genomic technologies enable researchers to identify genes that are co-regulated with respect to specific experimental conditions. Numerous statistical approaches have been developed to identify differentially expressed genes. Because each approach can produce distinct gene sets, it is difficult for biologists to determine which statistical approach yields biologically relevant gene sets and is appropriate for their study. To address this issue, we implemented Latent Semantic Indexing (LSI) to determine the functional coherence of gene sets. An LSI model was built using over 1 million Medline abstracts for over 20,000 mouse and human genes annotated in Entrez Gene. The gene-to-gene LSI-derived similarities were used to calculate a literature cohesion p-value (LPv) for a given gene set using a Fisher's exact test. We tested this method against genes in more than 6,000 functional pathways annotated in Gene Ontology (GO) and found that approximately 75% of gene sets in GO biological process category and 90% of the gene sets in GO molecular function and cellular component categories were functionally cohesive (LPv<0.05). These results indicate that the LPv methodology is both robust and accurate. Application of this method to previously published microarray datasets demonstrated that LPv can be helpful in selecting the appropriate feature extraction methods. To enable real-time calculation of LPv for mouse or human gene sets, we developed a web tool called Gene-set Cohesion Analysis Tool (GCAT). GCAT can complement other gene set enrichment approaches by determining the overall functional cohesion of data sets, taking into account both explicit and implicit gene interactions reported in the biomedical literature. GCAT is freely available at http://binf1.memphis.edu/gcat.
ERIC Educational Resources Information Center
Journal of Aerospace Education, 1978
1978-01-01
Reviews educational resources for classroom teachers. Resources include books, films, journals, science project guides, and public TV weather briefings. Addresses for obtaining the materials are provided. (MA)
NASA Space Engineering Research Center for Utilization of Local Planetary Resources
NASA Technical Reports Server (NTRS)
Ramohalli, Kumar; Lewis, John S.
1991-01-01
In the processing of propellants, volatiles, and metals subject area, the following topics are discussed: reduction of lunar regolith; reduction of carbon dioxide; and reduction of carbonaceous materials. Other areas addressed include: (1) production of structural and refractory materials; (2) resource discovery and characterization; (3) system automation and optimization; and (4) database development. The majority of these topics are discussed with respect to the development of lunar and mars bases. Some main topics of interest include: asteroid resources, lunar resources, mars resources, materials processing, construction materials, propellant production, oxygen production, and space-based oxygen production plants.
48 CFR 1552.211-79 - Compliance with EPA Policies for Information Resources Management.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Policies for Information Resources Management. 1552.211-79 Section 1552.211-79 Federal Acquisition... Information Resources Management (OCT 2000) (a) Definition. Information Resources Management (IRM) is defined... includes both information itself, and the management of information and related resources such as personnel...
14 CFR 1216.319 - Environmental resources document.
Code of Federal Regulations, 2010 CFR
2010-01-01
... environmental resources document which describes the current environment at that field installation, including current information on the effects of NASA operations on the local environment. This document shall include information on the same environmental effects as included in an environmental impact statement...
14 CFR 1216.319 - Environmental resources document.
Code of Federal Regulations, 2011 CFR
2011-01-01
... environmental resources document which describes the current environment at that field installation, including current information on the effects of NASA operations on the local environment. This document shall include information on the same environmental effects as included in an environmental impact statement...
GRADE guidelines: 10. Considering resource use and rating the quality of economic evidence.
Brunetti, Massimo; Shemilt, Ian; Pregno, Silvia; Vale, Luke; Oxman, Andrew D; Lord, Joanne; Sisk, Jane; Ruiz, Francis; Hill, Suzanne; Guyatt, Gordon H; Jaeschke, Roman; Helfand, Mark; Harbour, Robin; Davoli, Marina; Amato, Laura; Liberati, Alessandro; Schünemann, Holger J
2013-02-01
In this article, we describe how to include considerations about resource utilization when making recommendations according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. We focus on challenges with rating the confidence in effect estimates (quality of evidence) and incorporating resource use into evidence profiles and Summary of Findings (SoF) tables. GRADE recommends that important differences in resource use between alternative management strategies should be included along with other important outcomes in the evidence profile and SoF table. Key steps in considering resources in making recommendations with GRADE are the identification of items of resource use that may differ between alternative management strategies and that are potentially important to decision makers, finding evidence for the differences in resource use, making judgments regarding confidence in effect estimates using the same criteria used for health outcomes, and valuing the resource use in terms of costs for the specific setting for which recommendations are being made. With our framework, decision makers will have access to concise summaries of recommendations, including ratings of the quality of economic evidence, and better understand the implications for clinical decision making. Copyright © 2013 Elsevier Inc. All rights reserved.
This page includes EPA's resources for students and teachers interested in hosting a waste-free lunch day at school. These resources include instructions, helpful tips, and directions for tracking success.
Discussion on water resources value accounting and its application
NASA Astrophysics Data System (ADS)
Guo, Biying; Huang, Xiaorong; Ma, Kai; Gao, Linyun; Wang, Yanqiu
2018-06-01
The exploration of the compilation of natural resources balance sheet has been proposed since 2013. Several elements of water resources balance sheet have been discussed positively in China, including basic concept, framework and accounting methods, which focused on calculating the amount of water resources with statistical methods but lacked the analysis of the interrelationship between physical volume and magnitude of value. Based on the study of physical accounting of water resources balance sheet, the connotation of water resources value is analyzed in combination with research on the value of water resources in the world. What's more, the theoretical framework, form of measurement and research methods of water resources value accounting are further explored. Taking Chengdu, China as an example, the index system of water resources balance sheet in Chengdu which includes both physical and valuable volume is established to account the depletion of water resources, environmental damage and ecological water occupation caused by economic and social water use. Moreover, the water resources balance sheet in this region which reflects the negative impact of the economy on the environment is established. It provides a reference for advancing water resources management, improving government and social investment, realizing scientific and rational allocation of water resources.
Using Current Resources to Implement Wellness Programming for Preschoolers
ERIC Educational Resources Information Center
Cirignano, Sherri M.
2013-01-01
Currently, there is a nationwide effort to include preschool-aged children in wellness efforts for the prevention of obesity. National resources include guidelines, best practices, and tip sheets to assist in the implementation of these interventions. The Let's Move! Child Care Checklist is a resource that can be used to assess the level at…
ERIC Educational Resources Information Center
Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.
Presented is a compilation of over 3,000 abstracts on print and non-print materials related to water quality and water resources education. Entries are included from all levels of governmental sources, private concerns, and educational institutions. Each entry includes: title, author, cross references, descriptors, and availability. (CLS)
ERIC Educational Resources Information Center
Morgan, Nicholas; Killion, Joellen
2018-01-01
This report investigates factors that drive teachers to embrace or challenge the use of products and services designed to support improvements in practice. Key elements of the study include: (1) Technology-based resources studied include those designed for video observations, peer feedback and collaboration, online professional learning, and…
Integrated tools for natural resources inventories in the 21st century
M. Hansen; T. Burk
2000-01-01
Includes 96 papers presented at the conference Integrated Tools for Natural Resources Inventories in the 21st Century, August 16-20, 1998, in Boise, Idaho, USA. This conference drew several hundred forest inventory and related professionals from multiple organizational levels and over 30 foreign countries. Topics covered include those related to natural resource...
Educators Resource Directory. 2017/2018 Edition
ERIC Educational Resources Information Center
Grey House Publishing, 2017
2017-01-01
"Educators Resource Directory" is designed to provide educators, administrators, and other education professionals with immediate access to a unique combination of educational resources, along with important educational statistics and rankings. "Educators Resource Directory" includes associations, publications, trade shows,…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-15
...., Larsen and Toubro Limited, MRI Network/Manta Resources, Inc., Omni Resources, Premier Temporary Staffing...., Larsen and Toubro Limited, MRI Network/Manta Resources, Inc., Omni Resources, Premier Temporary Staffing...
NASA Technical Reports Server (NTRS)
2004-01-01
The topics addressed in the conference paper abstracts contained in this document include: extracting resources from the Moon and Mars, equipment for in situ resource utilization, mission planning for resource extraction, drilling on Mars, and simulants for lunar soil and minerals.
Multicriteria decision analysis applied to Glen Canyon Dam
Flug, M.; Seitz, H.L.H.; Scott, J.F.
2000-01-01
Conflicts in water resources exist because river-reservoir systems are managed to optimize traditional benefits (e.g., hydropower and flood control), which are historically quantified in economic terms, whereas natural and environmental resources, including in-stream and riparian resources, are more difficult or impossible to quantify in economic terms. Multicriteria decision analysis provides a quantitative approach to evaluate resources subject to river basin management alternatives. This objective quantification method includes inputs from special interest groups, the general public, and concerned individuals, as well as professionals for each resource considered in a trade-off analysis. Multicriteria decision analysis is applied to resources and flow alternatives presented in the environmental impact statement for Glen Canyon Dam on the Colorado River. A numeric rating and priority-weighting scheme is used to evaluate 29 specific natural resource attributes, grouped into seven main resource objectives, for nine flow alternatives enumerated in the environmental impact statement.
New drug information resources for pharmacists at the National Library of Medicine.
Knoben, James E; Phillips, Steven J
2014-01-01
To provide an overview of selected drug information-related databases of the National Library of Medicine (NLM), with a focus on newer resources that support the professional information needs of pharmacists and other health care providers. NLM, which is the world's largest medical library, provides an array of bibliographic, factual, and evidence-based drug, herbal remedy, and dietary supplement information resources. Five of the more recently introduced online resources include areas of particular importance to pharmacists, including a repository of current product labeling/package inserts, with automated search links to associated information resources; a portal to drug information that allows pharmacists to search multiple databases simultaneously and link to related medication and health care information resources; authoritative information on the effects of medications, herbal remedies, and dietary supplements in nursing infants and their mothers; comprehensive information, including a case registry, on the potential for liver toxicity due to drugs, herbal remedies, and dietary supplements; and a pill identification system with two intuitive search methodologies. NLM provides several clinical-scientific drug information resources that are particularly useful in meeting the professional information needs of pharmacists.
Cleary, James; Ddungu, Henry; Distelhorst, Sandra R; Ripamonti, Carla; Rodin, Gary M; Bushnaq, Mohammad A; Clegg-Lamptey, Joe N; Connor, Stephen R; Diwani, Msemo B; Eniu, Alexandru; Harford, Joe B; Kumar, Suresh; Rajagopal, M R; Thompson, Beti; Gralow, Julie R; Anderson, Benjamin O
2013-10-01
Many women diagnosed with breast cancer in low- and middle-income countries (LMICs) present with advanced-stage disease. While cure is not a realistic outcome, site-specific interventions, supportive care, and palliative care can achieve meaningful outcomes and improve quality of life. As part of the 5th Breast Health Global Initiative (BHGI) Global Summit, an expert international panel identified thirteen key resource recommendations for supportive and palliative care for metastatic breast cancer. The recommendations are presented in three resource-stratified tables: health system resource allocations, resource allocations for organ-based metastatic breast cancer, and resource allocations for palliative care. These tables illustrate how health systems can provide supportive and palliative care services for patients at a basic level of available resources, and incrementally add services as more resources become available. The health systems table includes health professional education, patient and family education, palliative care models, and diagnostic testing. The metastatic disease management table provides recommendations for supportive care for bone, brain, liver, lung, and skin metastases as well as bowel obstruction. The third table includes the palliative care recommendations: pain management, and psychosocial and spiritual aspects of care. The panel considered pain management a priority at a basic level of resource allocation and emphasized the need for morphine to be easily available in LMICs. Regular pain assessments and the proper use of pharmacologic and non-pharmacologic interventions are recommended. Basic-level resources for psychosocial and spiritual aspects of care include health professional and patient and family education, as well as patient support, including community-based peer support. Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.
Science Education Resource Assistant for Science Teachers. [CD- ROM].
ERIC Educational Resources Information Center
ERIC Clearinghouse for Science, Mathematics, and Environmental Education, Columbus, OH.
This CD-ROM provides a collection of Internet resources as well as K-16 related science materials and is divided into two sections. "Online Resources" includes information on the Educational Resources Information Center (ERIC), National Standards, AAAS Project 2061 Resources, U.S. Department of Education, Third International Mathematics…
Science Education Resource Assistant for Researchers. [CD-ROM].
ERIC Educational Resources Information Center
ERIC Clearinghouse for Science, Mathematics, and Environmental Education, Columbus, OH.
This CD-ROM provides a collection of Internet resources as well as K-16 related science materials and is divided into two sections. "Online Resources" includes information on the Educational Resources Information Center (ERIC), National Standards, AAAS Project 2061 Resources, U.S. Department of Education, Third International Mathematics…
NASA CORE (Central Operation of Resources for Educators) Educational Materials Catalog
NASA Technical Reports Server (NTRS)
1998-01-01
This educational materials catalog presents NASA CORE (Central Operation of Resources for Educators). The topics include: 1) Videocassettes (Aeronautics, Earth Resources, Weather, Space Exploration/Satellites, Life Sciences, Careers); 2) Slide Programs; 3) Computer Materials; 4) NASA Memorabilia/Miscellaneous; 5) NASA Educator Resource Centers; 6) and NASA Resources.
Effects of climate change on cultural resources [Chapter 12
Tom H. Flanigan; Charmaine Thompson; William G. Reed
2018-01-01
As with all resources on public lands, cultural resources are subject to environmental forces such as climate change. Climate change can affect cultural resources directly (e.g., heat, precipitation) or indirectly (e.g., vegetation, wildfire, flooding). Cultural resources include archaeological sites, cultural landscapes, ethnohistoric and historic structures and...
Investigating the Marine Environment and Its Resources, Part II.
ERIC Educational Resources Information Center
Lien, Violetta F.
This is the second of two volumes comprising a resource unit designed to help students become more knowledgeable about the marine environment and its resources. Included in this volume are discussions of changes in the human and marine environment, human needs, marine resources, living marine resources, marine transportation, marine energy…
ERIC Educational Resources Information Center
Ziegler, Albert; Chandler, Kimberley L.; Vialle, Wilma; Stoeger, Heidrun
2017-01-01
Based on the Actiotope Model of Giftedness, this article introduces a learning-resource-oriented approach for gifted education. It provides a comprehensive categorization of learning resources, including five exogenous learning resources termed "educational capital" and five endogenous learning resources termed "learning…
43 CFR 423.29 - Natural and cultural resources.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Natural and cultural resources. 423.29... of Conduct § 423.29 Natural and cultural resources. (a) You must not destroy, injure, deface, remove, search for, disturb, or alter natural resources or cultural resources, including abandoned buildings or...
43 CFR 423.29 - Natural and cultural resources.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Natural and cultural resources. 423.29... of Conduct § 423.29 Natural and cultural resources. (a) You must not destroy, injure, deface, remove, search for, disturb, or alter natural resources or cultural resources, including abandoned buildings or...
Bartsch-Winkler, S.; Sutphin, D.M.; Ball, M.M.; Korzeb, S.L.; Kness, R.F.; Dutchover, J.T.
1993-01-01
In this summary of two comprehensive resource reports produced by the U.S. Bureau of Mines and the U.S. Geological Survey for the U.S. Bureau of Land Management, we discuss the mineral- and energyresource endowment of the 14-millon-acre Roswell Resource Area, New Mexico, managed by the Bureau of Land Management. The Bureau and Survey reports result from separate studies that are compilations of published and unpublished data and integrate new findings on the geology, geochemistry, geophysics, mineral, industrial, and energy commodities, and resources for the seven-county area. The reports have been used by the Bureau of Land Management in preparation of the Roswell Resource Area Resource Management Plan, and will have future use in nationwide mineral- and energy-resource inventories and assessments, as reference and training documents, and as public-information tools. In the Roswell Resource Area, many metals, industrial mineral commodities, and energy resources are being, or have been, produced or prospected. These include metals and high-technology materials, such as copper, gold, silver, thorium, uranium and/or vanadium, rare-earth element minerals, iron, manganese, tungsten, lead, zinc, and molybdenum; industrial mineral resources, including barite, limestone/dolomite, caliche, clay, fluorspar, gypsum, scoria, aggregate, and sand and gravel; and fuels and associated resources, such as oil, gas, tar sand and heavy oil, coal, and gases associated with hydrocarbons. Other commodities that have yet to be identified in economic concentrations include potash, halite, polyhalite, anhydrite, sulfur, feldspar, building stone and decorative rock, brines, various gases associated with oil and gas exploration, and carbon dioxide. ?? 1993 Oxford University Press.
30 CFR 250.211 - What must the EP include?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What must the EP include? 250.211 Section 250.211 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF... Information Contents of Exploration Plans (ep) § 250.211 What must the EP include? Your EP must include the...
1980-12-01
SUPPLEMENTARY NOTES 19. KEY WORDS (Continue on reverse aide if neceeary aod identify by block number) Bulk cargo Market demand analysis Iron Commodity resource...shown below. The study included a Commodity Resource Inventory, a Modal Split Analysis and a Market Demand Analysis. The work included investigation...resource inventory, a modal split analysis and a market demand analysis. The work included investigation and analyses of the production
National parks. (Latest citations from the NTIS database). Published Search
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
The bibliography contains citations concerning U.S. and foreign national parks. Citations discuss terrestrial biology, botany, coastal biology, fire ecology, endangered and exotic species, and resource analysis. Topics also include the impact of park visitors on natural resources in the parks, resource management, planning, and mapping. Information about specific parks including Rocky Mountain, Great Smoky Mountains, Redwood, Grand Canyon, Sequoia, Glacier Bay, and others is presented. (Contains a minimum of 55 citations and includes a subject term index and title list.)
Resource depletion promotes automatic processing: implications for distribution of practice.
Scheel, Matthew H
2010-12-01
Recent models of cognition include two processing systems: an automatic system that relies on associative learning, intuition, and heuristics, and a controlled system that relies on deliberate consideration. Automatic processing requires fewer resources and is more likely when resources are depleted. This study showed that prolonged practice on a resource-depleting mental arithmetic task promoted automatic processing on a subsequent problem-solving task, as evidenced by faster responding and more errors. Distribution of practice effects (0, 60, 120, or 180 sec. between problems) on rigidity also disappeared when groups had equal time on resource-depleting tasks. These results suggest that distribution of practice effects is reducible to resource availability. The discussion includes implications for interpreting discrepancies in the traditional distribution of practice effect.
Online Mental Health Resources in Rural Australia: Clinician Perceptions of Acceptability
Holloway, Kristi; Riley, Geoffrey; Auret, Kirsten
2013-01-01
Background Online mental health resources have been proposed as an innovative means of overcoming barriers to accessing rural mental health services. However, clinicians tend to express lower satisfaction with online mental health resources than do clients. Objective To understand rural clinicians’ attitudes towards the acceptability of online mental health resources as a treatment option in the rural context. Methods In-depth interviews were conducted with 21 rural clinicians (general practitioners, psychologists, psychiatrists, and clinical social workers). Interviews were supplemented with rural-specific vignettes, which described clinical scenarios in which referral to online mental health resources might be considered. Symbolic interactionism was used as the theoretical framework for the study, and interview transcripts were thematically analyzed using a constant comparative method. Results Clinicians were optimistic about the use of online mental health resources into the future, showing a preference for integration alongside existing services, and use as an adjunct rather than an alternative to traditional approaches. Key themes identified included perceptions of resources, clinician factors, client factors, and the rural and remote context. Clinicians favored resources that were user-friendly and could be integrated into their clinical practice. Barriers to use included a lack of time to explore resources, difficulty accessing training in the rural environment, and concerns about the lack of feedback from clients. Social pressure exerted within professional clinical networks contributed to a cautious approach to referring clients to online resources. Conclusions Successful implementation of online mental health resources in the rural context requires attention to clinician perceptions of acceptability. Promotion of online mental health resources to rural clinicians should include information about resource effectiveness, enable integration with existing services, and provide opportunities for renegotiating the socially defined role of the clinician in the eHealth era. PMID:24007949
Online mental health resources in rural Australia: clinician perceptions of acceptability.
Sinclair, Craig; Holloway, Kristi; Riley, Geoffrey; Auret, Kirsten
2013-09-05
Online mental health resources have been proposed as an innovative means of overcoming barriers to accessing rural mental health services. However, clinicians tend to express lower satisfaction with online mental health resources than do clients. To understand rural clinicians' attitudes towards the acceptability of online mental health resources as a treatment option in the rural context. In-depth interviews were conducted with 21 rural clinicians (general practitioners, psychologists, psychiatrists, and clinical social workers). Interviews were supplemented with rural-specific vignettes, which described clinical scenarios in which referral to online mental health resources might be considered. Symbolic interactionism was used as the theoretical framework for the study, and interview transcripts were thematically analyzed using a constant comparative method. Clinicians were optimistic about the use of online mental health resources into the future, showing a preference for integration alongside existing services, and use as an adjunct rather than an alternative to traditional approaches. Key themes identified included perceptions of resources, clinician factors, client factors, and the rural and remote context. Clinicians favored resources that were user-friendly and could be integrated into their clinical practice. Barriers to use included a lack of time to explore resources, difficulty accessing training in the rural environment, and concerns about the lack of feedback from clients. Social pressure exerted within professional clinical networks contributed to a cautious approach to referring clients to online resources. Successful implementation of online mental health resources in the rural context requires attention to clinician perceptions of acceptability. Promotion of online mental health resources to rural clinicians should include information about resource effectiveness, enable integration with existing services, and provide opportunities for renegotiating the socially defined role of the clinician in the eHealth era.
Environmental Assessment for Airborne Laser Debris Management Vandenberg Air Force Base, California
2008-07-01
hazardous waste management, water resources, air quality, and biological resources. Based on the analysis of the Proposed Action and No-Action...aesthetics, hazardous materials management, soils and geology, noise, cultural resources, and environmental justice. The resources analyzed in more detail...include: health and safety, hazardous waste management, water resources, air quality, and biological resources. Environmental Effects Under the
NASA Astrophysics Data System (ADS)
Sahu, H. K.; Singh, S. N.
2015-04-01
This paper discusses and presents a comparative case study of two libraries in Pune, India, Inter-University Centre for Astronomy and Astrophysics and Information Centre and Library of National Institute of Virology (Indian Council of Medical Research). It compares how both libraries have managed their e-resource collections, including acquisitions, subscriptions, and consortia arrangements, while also developing a collection of their own resources, including pre-prints and publications, video lectures, and other materials in an institutional repository. This study illustrates how difficult it is to manage electronic resources in a developing country like India, even though electronic resources are used more than print resources. Electronic resource management can be daunting, but with a systematic approach, various problems can be solved, and use of the materials will be enhanced.
40 CFR 300.610 - Indian tribes.
Code of Federal Regulations, 2010 CFR
2010-07-01
... behalf of the Indian tribes as trustees for the natural resources, including their supporting ecosystems..., destruction of, loss of, or threat to natural resources, including their supporting ecosystems as a result of...
40 CFR 300.610 - Indian tribes.
Code of Federal Regulations, 2012 CFR
2012-07-01
... behalf of the Indian tribes as trustees for the natural resources, including their supporting ecosystems..., destruction of, loss of, or threat to natural resources, including their supporting ecosystems as a result of...
40 CFR 300.610 - Indian tribes.
Code of Federal Regulations, 2011 CFR
2011-07-01
... behalf of the Indian tribes as trustees for the natural resources, including their supporting ecosystems..., destruction of, loss of, or threat to natural resources, including their supporting ecosystems as a result of...
40 CFR 300.610 - Indian tribes.
Code of Federal Regulations, 2013 CFR
2013-07-01
... behalf of the Indian tribes as trustees for the natural resources, including their supporting ecosystems..., destruction of, loss of, or threat to natural resources, including their supporting ecosystems as a result of...
40 CFR 300.610 - Indian tribes.
Code of Federal Regulations, 2014 CFR
2014-07-01
... behalf of the Indian tribes as trustees for the natural resources, including their supporting ecosystems..., destruction of, loss of, or threat to natural resources, including their supporting ecosystems as a result of...
Green Power Partnership Resource Library: Solicitations
Green Power Partnership Resource Library includes documents meant to aid organizations and individuals in navigating the renewable energy procurement and renewable energy project development processes. It includes guidance documents, templates and actual e
Sustainable Biomass Resource Development and Use | Energy Analysis | NREL
Sustainable Biomass Resource Development and Use Sustainable Biomass Resource Development and Use A sustainability analysis includes biomass resource use and impact assessment. This analysis examines how we can use existing resources in a sustainable manner. It also examines the environmental and socio-economic
Recovery and Utilization of Extraterrestrial Resources
NASA Technical Reports Server (NTRS)
2004-01-01
This special bibliography includes the extraction, processing, and utilization of lunar, planetary, and asteroid resources; mining and excavation equipment, oxygen and propellant production; and in situ resource utilization.
NASA Astrophysics Data System (ADS)
Carroll, J.; McNeal, K. S.; Williams, C. C.; Paz, J. O.; Cho, H. "; Nair, U. S.; Geroux, J.; Guthrie, C.; Wright, K.; Hill, J.
2011-12-01
The Climate Literacy Partnership in the Southeast (CLiPSE) is a part of the Climate Change Education Program supported by the National Science Foundation (http://CLiPSE-project.org). The established CLiPSE partnership is dedicated to improving climate literacy in the southeast and promoting scientifically accurate, formal educational resources for the K-12 classroom audience, as well as informal educational resources for audiences such as agriculture, education, leisure, and religious organizations, to name a few. The CLiPSE project has been successful in creating partnerships with the National Geographic Alliances, Departments of Education, and Mississippi Environmental Education Alliance, among others, to determine an effective strategic plan for reaching K-12 audiences. One goal in the strategic plan is to create a catalog of climate change education resources that are aligned to state standards in the SE. Eighty-seven resources from the Climate Literacy and Energy Awareness Network (http://cleanet.org) have been aligned with the state education standards for grades six through twelve in the southeast, beginning with science in Mississippi and expanding to include science and math in the remaining SE states. The criteria for aligning the existing resources includes: matching key terms, topics, and lesson activities with the content strands and essential skills included in the state science framework. By developing a searchable database containing climate resources already aligned with state standards, CLiPSE will have made these resources more appealing to educators in the SE, increasing the likelihood of resources being implemented in the classroom. The CLiPSE Climate Science Team has also created an inventory of scientifically sound, informal resources, which will be available for dispersion to appropriate audiences and communities. Cataloged resources, both formal and informal, grouped by a variety of means, to include audience, grade level, and resource origin (e.g. government agency, organization, museum, climate-related websites, etc.), will be made available to the public through the CLiPSE website, promoting accessibility of these resources to the various CLiPSE publics. The process of alignment and vetting will be discussed in this paper, along with the information and education "gaps" that exist for the specific CLiPSE audiences in the SE US.
Multimedia: Beyond the Desktop.
ERIC Educational Resources Information Center
Galbreath, Jeremy
1993-01-01
Describes the Central Media Resource System (CMRS), a method that allows multimedia instruction to large groups of students. Highlights include the information infrastructure, including fiber optics and coaxial cable; use of the CMRS in the classroom and in the media resource center; and future possibilities, including local and wide area…
Kon, Alexander A.; Schilling, Debie A.; Heitman, Elizabeth; Steneck, Nicholas H.; DuBois, James M.
2011-01-01
Instruction in the responsible conduct of research (RCR) is required for all trainees funded by the National Institues of Health (NIH) or National Science Foundation (NSF). A recent Delphi study identified 53 key topics in 7 core areas that RCR education experts felt should be included in this instruction, which is required of many trainees in clinical and translational research. We performed a content analysis of major textbooks and online resources used in RCR instruction to determine the extent to which the 53 key topics identified in the Delphi study are covered by these resources. Textbooks and online resources used in RCR education at Clinical and Translational Science Award institutions were identified via survey. These resources were subjected to a content analysis. The 53 key topics identified in the Delphi study formed the basis of these analyses. We identified 10 textbooks and 1 online resource currently in use. Of the 53 key topics, only 4 were included in all 11 resources, and another 12 were included in 10. Twenty-three topics were covered in fewer than 65% of the resources, and two topics were absent from nearly all. Educators in clinical and translational research should be aware of key topics that are not covered in the RCR textbooks and online resources they may use and should consider augmenting discussion of such topics with other materials. PMID:21766046
NASA Astrophysics Data System (ADS)
East, J. A., II
2016-12-01
The U.S. Geological Survey's (USGS) Eastern Energy Resources Science Center (EERSC) has an ongoing project which has mapped coal chemistry and stratigraphy since 1977. Over the years, the USGS has collected various forms of coal data and archived that data into the National Coal Resources Data System (NCRDS) database. NCRDS is a repository that houses data from the major coal basins in the United States and includes information on location, seam thickness, coal rank, geologic age, geographic region, geologic province, coalfield, and characteristics of the coal or lithology for that data point. These data points can be linked to the US Coal Quality Database (COALQUAL) to include ultimate, proximate, major, minor and trace-element data. Although coal is an inexpensive energy provider, the United States has shifted away from coal usage recently and branched out into other forms of non-renewable and renewable energy because of environmental concerns. NCRDS's primary method of data capture has been USGS field work coupled with cooperative agreements with state geological agencies and universities doing coal-related research. These agreements are on competitive five-year cycles that have evolved into larger scope research efforts including solid fuel resources such as coal-bed methane, shale gas and oil. Recently these efforts have expanded to include environmental impacts of the use of fossil fuels, which has allowed the USGS to enter into agreements with states for the Geologic CO2 Storage Resources Assessment as required by the Energy Independence and Security Act. In 2016 they expanded into research areas to include geothermal, conventional and unconventional oil and gas. The NCRDS and COALQUAL databases are now online for the public to use, and are in the process of being updated to include new data for other energy resources. Along with this expansion of scope, the database name will change to the National Energy Resources Data System (NERDS) in FY 2017.
Teacher's Guide to Resources on Asia.
ERIC Educational Resources Information Center
Brigham Young Univ., Provo, UT. Center for International and Area Studies.
Intended for elementary, secondary, and college level teachers of Asian studies, this directory describes resources on Asia. The directory has two major sections. The first section describes "National Resources." Included are professional organizations, resource guides and bibliographies, periodicals, and film guides and sources.…
Measuring Resource Utilization: A Systematic Review of Validated Self-Reported Questionnaires.
Leggett, Laura E; Khadaroo, Rachel G; Holroyd-Leduc, Jayna; Lorenzetti, Diane L; Hanson, Heather; Wagg, Adrian; Padwal, Raj; Clement, Fiona
2016-03-01
A variety of methods may be used to obtain costing data. Although administrative data are most commonly used, the data available in these datasets are often limited. An alternative method of obtaining costing is through self-reported questionnaires. Currently, there are no systematic reviews that summarize self-reported resource utilization instruments from the published literature.The aim of the study was to identify validated self-report healthcare resource use instruments and to map their attributes.A systematic review was conducted. The search identified articles using terms like "healthcare utilization" and "questionnaire." All abstracts and full texts were considered in duplicate. For inclusion, studies had to assess the validity of a self-reported resource use questionnaire, to report original data, include adult populations, and the questionnaire had to be publically available. Data such as type of resource utilization assessed by each questionnaire, and validation findings were extracted from each study.In all, 2343 unique citations were retrieved; 2297 were excluded during abstract review. Forty-six studies were reviewed in full text, and 15 studies were included in this systematic review. Six assessed resource utilization of patients with chronic conditions; 5 assessed mental health service utilization; 3 assessed resource utilization by a general population; and 1 assessed utilization in older populations. The most frequently measured resources included visits to general practitioners and inpatient stays; nonmedical resources were least frequently measured. Self-reported questionnaires on resource utilization had good agreement with administrative data, although, visits to general practitioners, outpatient days, and nurse visits had poorer agreement.Self-reported questionnaires are a valid method of collecting data on healthcare resource utilization.
Exploring Global Exposure Factors Resources for Use in ...
This publication serves as a global comprehensive resource for readers seeking exposure factor data and information relevant to consumer exposure assessment. It describes the types of information that may be found in various official surveys and online and published resources. The relevant exposure factors cover a broad range, including general exposure factor data found in published compendia and databases and resources about specific exposure factors, such as human activity patterns and housing information. Also included are resources on exposure factors related to specific types of consumer products and the associated patterns of use, such as for a type of personal care product or a type of children’s toy. Further, a section on using exposure factors for designing representative exposure scenarios is included, along with a look into the future for databases and other exposure science developments relevant for consumer exposure assessment. Review article in the International Journal of Environmental Research and Public Health
Exploring Global Exposure Factors Resources for Use in Consumer Exposure Assessments.
Zaleski, Rosemary T; Egeghy, Peter P; Hakkinen, Pertti J
2016-07-22
This publication serves as a global comprehensive resource for readers seeking exposure factor data and information relevant to consumer exposure assessment. It describes the types of information that may be found in various official surveys and online and published resources. The relevant exposure factors cover a broad range, including general exposure factor data found in published compendia and databases and resources about specific exposure factors, such as human activity patterns and housing information. Also included are resources on exposure factors related to specific types of consumer products and the associated patterns of use, such as for a type of personal care product or a type of children's toy. Further, a section on using exposure factors for designing representative exposure scenarios is included, along with a look into the future for databases and other exposure science developments relevant for consumer exposure assessment.
An asset-focused health needs assessment in a rural community in North India.
Mathias, Kaaren R; Mathias, Joseph M P; Hill, Philip C
2015-03-01
Health needs assessment (HNA) targets health resources to needs yet is rarely used in low-resource contexts such as the Indian villages. The authors combined rapid participatory appraisal (RPA) and HNA tools into 4 steps: (a) define HNA parameters, objectives, and community; (b) describe community demographics, health status, felt needs, assets, and health services; (c) analysis; and (d) design interventions considering felt needs, assets, impact potential, and organizational resources. Community felt needs focused on lack of access to personal health services. Major morbidities included respiratory and diarrheal disease and maternal/child health problems. Formal anthropometry revealed high prevalence of underweight and stunting. Community assets included high land ownership, educated unmarried women, and operational government services. In low-resource developing country contexts with poor information systems, HNA is possible and useful. Including RPA and community participation to also assess assets resulted in programs responding to communities' needs using existing resources. © 2011 APJPH.
Exploring Global Exposure Factors Resources for Use in Consumer Exposure Assessments
Zaleski, Rosemary T.; Egeghy, Peter P.; Hakkinen, Pertti J.
2016-01-01
This publication serves as a global comprehensive resource for readers seeking exposure factor data and information relevant to consumer exposure assessment. It describes the types of information that may be found in various official surveys and online and published resources. The relevant exposure factors cover a broad range, including general exposure factor data found in published compendia and databases and resources about specific exposure factors, such as human activity patterns and housing information. Also included are resources on exposure factors related to specific types of consumer products and the associated patterns of use, such as for a type of personal care product or a type of children’s toy. Further, a section on using exposure factors for designing representative exposure scenarios is included, along with a look into the future for databases and other exposure science developments relevant for consumer exposure assessment. PMID:27455300
NASA Technical Reports Server (NTRS)
Foushee, H. Clayton
1982-01-01
There is increasing evidence that many air transport incidents and accidents are the result of the improper or inadequate utilization of the resources accessible to flight dock crew members. These resources obviously include the hardware and technical information necessary for the safe and efficient conduct of the flight, but they also Include the human resources which must be coordinated effectively. The focus of this paper is upon the human resources, and how communication styles, socio-psychological factors, and personality characteristics can affect crew coordination.
Skylab experiments. Volume 2: Remote sensing of earth resources
NASA Technical Reports Server (NTRS)
1973-01-01
This volume covers the broad area of earth resources in which Skylab experiments will be performed. A brief description of the Skylab program, its objectives, and vehicles is included. Section 1 introduces the concept and historical significance of remote sensing, and discusses the major scientific considerations involved in remotely sensing the earth's resources. Sections 2 through 6 provide a description of the individual earth resource sensors and experiments to be performed. Each description includes a discussion of the experiment background and scientific objectives, the equipment involved, and a discussion of significant experiment performance areas.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Larsen, A.
This study examines various energy resources in Utah including oil impregnated rocks (oil shale and oil sand deposits), geothermal, coal, uranium, oil and natural gas in terms of the following dimensions: resurce potential and location; resource technology, development and production status; resource development requirements; potential environmental and socio-economic impacts; and transportation tradeoffs. The advantages of minemouth power plants in comparison to combined cycle or hybrid power plants are also examined. Annotative bibliographies of the energy resources are presented in the appendices. Specific topics summarized in these annotative bibliographies include: economics, environmental impacts, water requirements, production technology, and siting requirements.
43 CFR 2300.0-5 - Definitions.
Code of Federal Regulations, 2012 CFR
2012-10-01
... natural resource indigenous to a particular land area, including, but not limited to, mineral, timber..., enhancement or development of natural resources or resource values indigenous to or associated with a...
43 CFR 2300.0-5 - Definitions.
Code of Federal Regulations, 2013 CFR
2013-10-01
... natural resource indigenous to a particular land area, including, but not limited to, mineral, timber..., enhancement or development of natural resources or resource values indigenous to or associated with a...
43 CFR 2300.0-5 - Definitions.
Code of Federal Regulations, 2014 CFR
2014-10-01
... natural resource indigenous to a particular land area, including, but not limited to, mineral, timber..., enhancement or development of natural resources or resource values indigenous to or associated with a...
43 CFR 2300.0-5 - Definitions.
Code of Federal Regulations, 2011 CFR
2011-10-01
... natural resource indigenous to a particular land area, including, but not limited to, mineral, timber..., enhancement or development of natural resources or resource values indigenous to or associated with a...
Do GPs use electronic mental health resources? - a qualitative study.
Austin, David; Pier, Ciaran; Mitchell, Joanna; Schattner, Peter; Wade, Victoria; Pierce, David; Klein, Britt
2006-05-01
The Better Outcomes in Mental Health Care (BOMHC) initiative encourages general practitioners to use electronic mental health resources (EMHRs) during consultation with patients requiring psychological assistance. However, there is little data on GPs' acceptance and use of EMHRs. Semistructured interviews were conducted with 27 GPs to determine their attitude toward EMHRs, and their use during consultation with patients. Few GPs reported frequently using EMHRs in consultation. Identified barriers to use included lack of familiarity with information technology, and insufficient knowledge of available resources. Identified advantages of electronic resources included high patient acceptance, time efficiency, and improved quality of information. General practitioners recognise several advantages of utilising electronic resources for managing patients with mental illness. However, GPs are not sufficiently familiar with electronic resources to use them effectively. This could be overcome by education.
Use of Mobile Devices to Access Resources Among Health Professions Students: A Systematic Review.
Mi, Misa; Wu, Wendy; Qiu, Maylene; Zhang, Yingting; Wu, Lin; Li, Jie
2016-01-01
This systematic review examines types of mobile devices used by health professions students, kinds of resources and tools accessed via mobile devices, and reasons for using the devices to access the resources and tools. The review included 20 studies selected from articles published in English between January 2010 and April 2015, retrieved from PubMed and other sources. Data extracted included participants, study designs, mobile devices used, mobile resources/apps accessed, outcome measures, and advantages of and barriers to using mobile devices. The review indicates significant variability across the studies in terms of research methods, types of mobile programs implemented, resources accessed, and outcomes. There were beneficial effects of using mobile devices to access resources as well as conspicuous challenges or barriers in using mobile devices.
An Analysis of Physician Assistant LibGuides: A Tool for Collection Development.
Johnson, Catherine V; Johnson, Scott Y
2017-01-01
The Physician Assistant (PA) specialty encompasses many subject areas and requires many types of library resources. An analysis of PA LibGuides was performed to determine most frequently recommended resources. A sample of LibGuides from U.S. institutions accredited by the Accreditation Review Commission on Education for the Physician Assistant (ARC-PA) was included in this study. Resources presented on guides were tabulated and organized by resource type. Databases and point-of-care tools were the types of resources listed by the most LibGuides. There were over 1,000 books listed on the 45 guides, including over 600 unique books listed. There were fewer journals listed, only 163. Overall, while the 45 LibGuides evaluated list many unique resources in each category, a librarian can create an accepted list of the most frequently listed resources from the data gathered.
Timber resource statistics for the central coast resource area of California.
Karen L. Waddell; Patricia M. Bassett
1996-01-01
This report is a summary of timber resource statistics for the Central Coast Resource Area of California, which includes Alameda, Contra Costa, Marin, Monterey, San Benito, San Francisco, San Luis Obispo, San Mateo, Santa Barbara, Santa Clara, Santa Cruz, Solano, and Ventura Counties. Data were collected as part of a statewide multi-resource inventory. The inventory...
Which Online Resources Are Right for Your Collection?
ERIC Educational Resources Information Center
Pearlmutter, Jane
1999-01-01
Discusses important considerations for library media specialists creating a virtual-resources-collection policy, including selecting the right resources, navigating licensing fees, and free, searchable online sources. A sidebar lists resources for evaluating Web sites and places that lead to recommended sites for students. (AEF)
Human Resource Management in Virtual Organizations. Research in Human Resource Management Series.
ERIC Educational Resources Information Center
Heneman, Robert L., Ed.; Greenberger, David B., Ed.
This document contains 14 papers on human resources (HR) and human resource management (HRM) in virtual organizations. The following papers are included: "Series Preface" (Rodger Griffeth); "Volume Preface" (Robert L. Heneman, David B. Greenberger); "The Virtual Organization: Definition, Description, and…
Natural Resources Bibliography.
ERIC Educational Resources Information Center
Hoadley, Irene Braden
This bibliography presents a modern definition of the conceptual framework from which to view natural resources, and affords access to information which examines resources from the social scientists point of view. It presents five broad divisions of activity or variables which include (1) Natural and Human Resources, (2) Epistomological and…
Idaho National Laboratory Cultural Resource Monitoring Report for FY 2009
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brenda R. Pace; Julie B. Braun
2009-10-01
This report describes the cultural resource monitoring activities of the Idaho National Laboratory’s (INL) Cultural Resource Management (CRM) Office during fiscal year 2009 (FY 2009). Throughout the year, thirty-eight cultural resource localities were revisited including: two locations with Native American human remains, one of which is a cave, two additional caves, twenty-two prehistoric archaeological sites, six historic homesteads, two historic stage stations, two historic trails, and two nuclear resources, including Experimental Breeder Reactor-I, which is a designated National Historic Landmark. Several INL project areas were also monitored in FY 2009 to assess project compliance with cultural resource recommendations and monitormore » the effects of ongoing project activities. Although impacts were documented at a few locations and trespassing citations were issued in one instance, no significant adverse effects that would threaten the National Register eligibility of any resources were observed. Monitoring also demonstrated that several INL projects generally remain in compliance with recommendations to protect cultural resources.« less
Selecting and implementing the PBS scheduler on an SGI Onyx 2/Orgin 2000.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bittner, S.
1999-06-28
In the Mathematics and Computer Science Division at Argonne, the demand for resources on the Onyx 2 exceeds the resources available for consumption. To distribute these scarce resources effectively, we need a scheduling and resource management package with multiple capabilities. In particular, it must accept standard interactive user logins, allow batch jobs, backfill the system based on available resources, and permit system activities such as accounting to proceed without interruption. The package must include a mechanism to treat the graphic pipes as a schedulable resource. Also required is the ability to create advance reservations, offer dedicated system modes for largemore » resource runs and benchmarking, and track the resources consumed for each job run. Furthermore, our users want to be able to obtain repeatable timing results on job runs. And, of course, package costs must be carefully considered. We explored several options, including NQE and various third-party products, before settling on the PBS scheduler.« less
Bunch, R.L.
1996-01-01
References to 898 water-resources publications are listed alphabetically by senior author and indexed by hydrographic-area name or other geographic features. Most of the publications were written between 1960 and 1995 by U.S. Geological Survey scientists and engineers of the Water Resources Division, Nevada District. Also included are references to publications by other Water Resources Division authors that deal with Nevada hydrology. References to publications written before 1960 are included to provide a historical perspective. The references include several types of Geological Survey book and map publications, as well as State-series reports, journal articles, conference and symposium papers, abstracts, and graduate- degree theses. Information on publication availability is provided also.
Renewable Energy Project Development Resource Directory
The Renewable Energy Project Development Resource Directory provides a curated list of solar project development resources for higher education and local government, including case studies, guidance, fact sheets, presentations, templates, and more.
To ontologise or not to ontologise: An information model for a geospatial knowledge infrastructure
NASA Astrophysics Data System (ADS)
Stock, Kristin; Stojanovic, Tim; Reitsma, Femke; Ou, Yang; Bishr, Mohamed; Ortmann, Jens; Robertson, Anne
2012-08-01
A geospatial knowledge infrastructure consists of a set of interoperable components, including software, information, hardware, procedures and standards, that work together to support advanced discovery and creation of geoscientific resources, including publications, data sets and web services. The focus of the work presented is the development of such an infrastructure for resource discovery. Advanced resource discovery is intended to support scientists in finding resources that meet their needs, and focuses on representing the semantic details of the scientific resources, including the detailed aspects of the science that led to the resource being created. This paper describes an information model for a geospatial knowledge infrastructure that uses ontologies to represent these semantic details, including knowledge about domain concepts, the scientific elements of the resource (analysis methods, theories and scientific processes) and web services. This semantic information can be used to enable more intelligent search over scientific resources, and to support new ways to infer and visualise scientific knowledge. The work describes the requirements for semantic support of a knowledge infrastructure, and analyses the different options for information storage based on the twin goals of semantic richness and syntactic interoperability to allow communication between different infrastructures. Such interoperability is achieved by the use of open standards, and the architecture of the knowledge infrastructure adopts such standards, particularly from the geospatial community. The paper then describes an information model that uses a range of different types of ontologies, explaining those ontologies and their content. The information model was successfully implemented in a working geospatial knowledge infrastructure, but the evaluation identified some issues in creating the ontologies.
14 CFR 135.330 - Crew resource management training.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Crew resource management training. 135.330... § 135.330 Crew resource management training. (a) Each certificate holder must have an approved crew resource management training program that includes initial and recurrent training. The training program...
14 CFR 135.330 - Crew resource management training.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Crew resource management training. 135.330... § 135.330 Crew resource management training. (a) Each certificate holder must have an approved crew resource management training program that includes initial and recurrent training. The training program...
14 CFR 135.330 - Crew resource management training.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Crew resource management training. 135.330... § 135.330 Crew resource management training. (a) Each certificate holder must have an approved crew resource management training program that includes initial and recurrent training. The training program...
Channeling a Community's Aging Resources.
ERIC Educational Resources Information Center
Smith, Daniel J.
This report addresses the issue of community utilization of resources for the elderly population. A strategy for channeling resources is presented, including: (1) design of a comprehensive aging services administration and delivery plan based on needs assessment data and a service resource inventory; (2) development of a service agencies network…
Educational Resources on the Internet.
ERIC Educational Resources Information Center
Lam, Kwan-Yau
The purpose of this paper is to introduce to school teachers and students resources on the Internet, and to provide updated information on selected resources. Following background information on the development of the Internet, its educational potentials are discussed, including resources for preparation of teaching materials, access for children…
Life Sciences: Curriculum Resources and Activities for School Librarians and Teachers.
ERIC Educational Resources Information Center
Bain, Amy; Richer, Janet; Weckman, Janet
This book provides resources to teachers and librarians for creating thematic units on specific topics targeting grades K-8. Each topic includes key concepts, comprehensive teaching resources, teaching resources (nonfiction children's literature), reading selections (fiction children's literature), science activities, creative writing and art…
ALA Guide to Medical & Health Sciences Reference
ERIC Educational Resources Information Center
ALA Editions, 2011
2011-01-01
This resource provides an annotated list of print and electronic biomedical and health-related reference sources, including Internet resources and digital image collections. Readers will find relevant research, clinical, and consumer health information resources. The emphasis is on resources within the United States, with a few representative…
Multicultural Resources on the Internet: An Introduction.
ERIC Educational Resources Information Center
Jacobson, Trudi E.
1995-01-01
Explores the Internet system and Internet resources for particular culture groups. The author provides some Internet definitions as well as descriptions of available resources listed by cultural group including resources for African American, Chicano/Latino, Native American, Middle Eastern/Jewish/Islamic, and Asian American/Asian people. (GR)
Earth Sciences: Curriculum Resources and Activities for School Librarians and Teachers.
ERIC Educational Resources Information Center
Bain, Amy; Richer, Janet; Weckman, Janet
This book provides resources to teachers and librarians for creating thematic units on specific topics targeting grades K-8. Each topic includes key concepts, comprehensive teaching resources, teaching resources (nonfiction children's literature), reading selections (fiction children's literature), science activities, creative writing and art…
ERIC Educational Resources Information Center
Council for Exceptional Children, Reston, VA. Center for Special Education Technology.
This set of 10 resource inventories provides listings of information and service resources organized by state or by subtopic. Listings typically include name, address, phone, and a contact person. The first inventory lists the 39 Alliance for Technology Access Centers which are community-based resources providing specific areas of expertise for…
Physical Sciences: Curriculum Resources and Activities for School Librarians and Teachers.
ERIC Educational Resources Information Center
Bain, Amy; Richer, Janet; Weckman, Janet
This book provides resources to teachers and librarians for creating thematic units on specific topics targeting grades K-8. Each topic includes key concepts, comprehensive teaching resources, teaching resources (nonfiction children's literature), reading selections (fiction children's literature), science activities, creative writing and art…
American Indian Youth Resource Guide.
ERIC Educational Resources Information Center
Bane, William; Goodluck, Charlotte
This document was produced by the Family Resource Center, a federally funded project designed to develop and share resources and information on youth services, child abuse and neglect, and child welfare in Region VIII, which includes Colorado, Utah, Wyoming, North Dakota, South Dakota, and Montana. This resource guide contains introductory…
2014-05-01
The basic systems of any society rarely can operate independently. Instead, they are dependent and often interdependent upon other entities. Such entities control the resources within their respective systems. Thus, coordination and control agencies require contracts or memoranda of understanding with these entities in order to assure access to the resources required during a crisis. These administrative structures include: (1) governmental institutions and agencies, including the military; (2) intergovernmental organisations; (3) nongovernmental organisations; (4) commercial private sector organisations; and (5) academic institutions. These dependencies create potential barriers to the provision of coordination and control including: (1) the complexity of the administrative structures with which coordination and control must interact; (2) the location of resources; (3) finding responsible person(s); (4) the competence and compatibility; (5) methods of access; (6) payment; (7) contracts and memoranda of understanding; (8) inventories of accessible resources; (9) competition for the mandate, power, and resources; and (10) jealousy. The need for potential interactions between administrative structures requires that agreements for the sharing of resources during crises be reached as part of planning and preparedness. Gaining an understanding of these relationships is an important area for research.
Nursing Reference Center: a point-of-care resource.
Vardell, Emily; Paulaitis, Gediminas Geddy
2012-01-01
Nursing Reference Center is a point-of-care resource designed for the practicing nurse, as well as nursing administrators, nursing faculty, and librarians. Users can search across multiple resources, including topical Quick Lessons, evidence-based care sheets, patient education materials, practice guidelines, and more. Additional features include continuing education modules, e-books, and a new iPhone application. A sample search and comparison with similar databases were conducted.
In Situ Resource Utilization (ISRU II) Technical Interchange Meeting
NASA Technical Reports Server (NTRS)
Kaplan, David (Compiler); Saunders, Stephen R. (Compiler)
1997-01-01
This volume contains extended abstracts that have been accepted for presentation at the In Situ Resource Utilization (ISRU II) Technical Interchange Meeting, November 18-19, 1997, at the Lunar and Planetary Institute, Houston, Texas. Included are topics which include: Extraterrestrial resources, in situ propellant production, sampling of planetary surfaces, oxygen production, water vapor extraction from the Martian atmosphere, gas generation, cryogenic refrigeration, and propellant transport and storage.
Timber resource statistics for the North Coast resource area of California 1994.
Karen L. Waddell; Patricia M. Bassett
1996-01-01
This report is a summary of timber resource statistics for the North Coast Resource Area of California, which includes Del Norte, Humboldt, Mendocino, and Sonoma Counties. Data were collected by the Pacific Northwest Research Station as part of a State-wide multi-resource inventory. The inventory sampled private and public lands except reserved areas and National...
ERIC Educational Resources Information Center
Wilmington Coll., OH. Peace Resource Center.
Over 130 print and nonprint peace education resources for use with adult groups and elementary, secondary, and college students are described. Audiovisuals may be rented and books may be purchased from the Wilmington College (Ohio) Peace Resource Center. Audiovisuals, including slides, videotapes and videotape cassettes, and 16mm films, are…
Science Indicators, 1976: Report of the National Science Board.
ERIC Educational Resources Information Center
National Science Foundation, Washington, DC. National Science Board.
This ninth annual report of the National Science Board presents the third assessment of the state of science in the United States. The assessment includes reports on the status and health of science including national resources and manpower. Indicators reviewed in the report include: international science and technology, resources for research and…
ERIC Educational Resources Information Center
Jones, Kent
Materials presented here include a variety of resources for teachers of Esperanto: a brief guide to Esperanto teaching, including suggested teacher qualifications, a listing of instructional materials and resources, including serials, with details of publication, activities in preparation for teaching, grade-level class activities, notes on…
Solar Project Development Pathway & Resources
The Local Government Solar Project Portal's Solar Project Development Pathway and Resources page details the major steps along the project development pathway and each step includes resources and tools to assist you with that step.
36 CFR 200.3 - Forest Service functions.
Code of Federal Regulations, 2011 CFR
2011-07-01
..., and (G) Physical and resource improvements needed to develop, protect, and use all resources are built..., including the five basic resources of timber, forest soil and water, range forage, wildlife and fish habitat...
Rethinking the Holidays. Teacher's Resources.
ERIC Educational Resources Information Center
Porter, Priscilla H.
1993-01-01
Maintains that holidays provide opportunities for teaching about history and cultural diversity. Presents a bibliographic essay of recommended resources for elementary teachers on this topic. Materials include reading resources, activity books, and audiovisual materials. (CFR)
Hall, William; Smith, Neale; Mitton, Craig; Urquhart, Bonnie; Bryan, Stirling
2018-01-01
Background: In order to meet the challenges presented by increasing demand and scarcity of resources, healthcare organizations are faced with difficult decisions related to resource allocation. Tools to facilitate evaluation and improvement of these processes could enable greater transparency and more optimal distribution of resources. Methods: The Resource Allocation Performance Assessment Tool (RAPAT) was implemented in a healthcare organization in British Columbia, Canada. Recommendations for improvement were delivered, and a follow up evaluation exercise was conducted to assess the trajectory of the organization’s priority setting and resource allocation (PSRA) process 2 years post the original evaluation. Results: Implementation of RAPAT in the pilot organization identified strengths and weaknesses of the organization’s PSRA process at the time of the original evaluation. Strengths included the use of criteria and evidence, an ability to reallocate resources, and the involvement of frontline staff in the process. Weaknesses included training, communication, and lack of program budgeting. Although the follow up revealed a regression from a more formal PSRA process, a legacy of explicit resource allocation was reported to be providing ongoing benefit for the organization. Conclusion: While past studies have taken a cross-sectional approach, this paper introduces the first longitudinal evaluation of PSRA in a healthcare organization. By including the strengths, weaknesses, and evolution of one organization’s journey, the authors’ intend that this paper will assist other healthcare leaders in meeting the challenges of allocating scarce resources. PMID:29626400
ERIC Educational Resources Information Center
Catlett, Camille
2010-01-01
Federally funded national centers offer high-quality products and resources for use by teachers, family members, and others. By design, they offer resources that are low cost or no cost. This article presents details about several centers that may have resources to support your work. They include: (1) Center for Early Literacy Learning (CELL); (2)…
State Resource Guide for School Volunteer Coordinators.
ERIC Educational Resources Information Center
South Carolina State Dept. of Education, Columbia.
This resource guide for school volunteer coordinators aids them in developing and maintaining a school volunteer program. Topics addressed include (1) making maximum use of community volunteer resources; (2) building a network of resource people and interfacing school support groups; (3) setting up the school volunteer program; (4)…
State Resource Guide for School Volunteer Coordinators.
ERIC Educational Resources Information Center
South Carolina State Dept. of Education, Columbia.
This resource guide was designed to help school volunteer coordinators develop and maintain a school volunteer program. Topics addressed include: (1) making maximum use of volunteer resources; (2) building a network of resource people from school support groups; (3) setting up a school volunteer program; (4) responsibilities of volunteers and…
Resource Manual for Alcohol and Other Drug Abuse Education in Internal Medicine.
ERIC Educational Resources Information Center
Bigby, JudyAnn, Ed.; England, Susan, Ed.
The resource manual provides guidelines and resources for individuals interested in integrating a substance abuse curriculum into existing programs for medical students and residents in internal medicine. Materials and resources appropriate for practicing physicians are also included. Three sections are: (1) a statement of minimum knowledge and…
Traumatic Brain Injury and Special Education: An Information Resource Guide.
ERIC Educational Resources Information Center
Stevens, Alice M.
This resource guide of annotated references on traumatic brain injury (TBI) was created to help educators locate information from such disciplines as neurology, neuropsychology, rehabilitation, and pediatric medicine. Twenty-four resources published from 1990 to 1994 are listed, with annotations. The resources include research reports/reviews,…
An Online Resource Site for Extension Master Gardener Coordinators
ERIC Educational Resources Information Center
Langellotto, Gail Ann; Dorn, Sheri
2016-01-01
Developing an online resource site for Extension master gardener (EMG) coordinators is an ongoing project for Extension collaborators. Begun in 2014, the website includes peer-reviewed resources focused on best practices in volunteer management and program administration. The website is organized according to nine resource categories (e.g.,…
A Basic Bibliography on Canada for Social Studies Educators.
ERIC Educational Resources Information Center
Yocum, Michael J.
1988-01-01
Presents a bibliography that provides materials on Canada available to social studies educators. Resources for teachers include teaching strategies, literature guides, and books on acid rain. Student resources include books that provide a perspective on Canadian life. (DB)
Earth resources-regional transfer activity contracts review
NASA Technical Reports Server (NTRS)
Bensko, J., Jr.; Daniels, J. L.; Downs, S. W., Jr.; Jones, N. L.; Morton, R. R.; Paludan, C. T.
1977-01-01
A regional transfer activity contracts review held by the Earth Resources Office was summarized. Contracts in the earth resources field primarily directed toward applications of satellite data and technology in solution of state and regional problems were reviewed. A summary of the progress of each contract was given in order to share experiences of researchers across a seven state region. The region included Missouri, Kentucky, Tennessee, Mississippi, Alabama, Georgia, and North Carolina. Research in several earth science disciplines included forestry, limnology, water resources, land use, geology, and mathematical modeling. The use of computers for establishment of information retrieval systems was also emphasized.
Developing integrated methods to address complex resource and environmental issues
Smith, Kathleen S.; Phillips, Jeffrey D.; McCafferty, Anne E.; Clark, Roger N.
2016-02-08
IntroductionThis circular provides an overview of selected activities that were conducted within the U.S. Geological Survey (USGS) Integrated Methods Development Project, an interdisciplinary project designed to develop new tools and conduct innovative research requiring integration of geologic, geophysical, geochemical, and remote-sensing expertise. The project was supported by the USGS Mineral Resources Program, and its products and acquired capabilities have broad applications to missions throughout the USGS and beyond.In addressing challenges associated with understanding the location, quantity, and quality of mineral resources, and in investigating the potential environmental consequences of resource development, a number of field and laboratory capabilities and interpretative methodologies evolved from the project that have applications to traditional resource studies as well as to studies related to ecosystem health, human health, disaster and hazard assessment, and planetary science. New or improved tools and research findings developed within the project have been applied to other projects and activities. Specifically, geophysical equipment and techniques have been applied to a variety of traditional and nontraditional mineral- and energy-resource studies, military applications, environmental investigations, and applied research activities that involve climate change, mapping techniques, and monitoring capabilities. Diverse applied geochemistry activities provide a process-level understanding of the mobility, chemical speciation, and bioavailability of elements, particularly metals and metalloids, in a variety of environmental settings. Imaging spectroscopy capabilities maintained and developed within the project have been applied to traditional resource studies as well as to studies related to ecosystem health, human health, disaster assessment, and planetary science. Brief descriptions of capabilities and laboratory facilities and summaries of some applications of project products and research findings are included in this circular. The work helped support the USGS mission to “provide reliable scientific information to describe and understand the Earth; minimize loss of life and property from natural disasters; manage water, biological, energy, and mineral resources; and enhance and protect our quality of life.” Activities within the project include the following:Spanned scales from microscopic to planetary;Demonstrated broad applications across disciplines;Included life-cycle studies of mineral resources;Incorporated specialized areas of expertise in applied geochemistry including mineralogy, hydrogeology, analytical chemistry, aqueous geochemistry, biogeochemistry, microbiology, aquatic toxicology, and public health; andIncorporated specialized areas of expertise in geophysics including magnetics, gravity, radiometrics, electromagnetics, seismic, ground-penetrating radar, borehole radar, and imaging spectroscopy.This circular consists of eight sections that contain summaries of various activities under the project. The eight sections are listed below:Laboratory Facilities and Capabilities, which includes brief descriptions of the various types of laboratories and capabilities used for the project;Method and Software Development, which includes summaries of remote-sensing, geophysical, and mineralogical methods developed or enhanced by the project;Instrument Development, which includes descriptions of geophysical instruments developed under the project;Minerals, Energy, and Climate, which includes summaries of research that applies to mineral or energy resources, environmental processes and monitoring, and carbon sequestration by earth materials;Element Cycling, Toxicity, and Health, which includes summaries of several process-oriented geochemical and biogeochemical studies and health-related research activities;Hydrogeology and Water Quality, which includes descriptions of innovative geophysical, remote-sensing, and geochemical research pertaining to hydrogeology and water-quality applications;Hazards and Disaster Assessment, which includes summaries of research and method development that were applied to natural hazards, human-caused hazards, and disaster assessments; andDatabases and Framework Studies, which includes descriptions of fundamental applications of geophysical studies and of the importance of archived data.
Davies, Tilman M.; Cornwall, Jon
2015-01-01
ABSTRACT Purpose: To investigate how musculoskeletal outpatient physiotherapists in public hospitals interact with and perceive clinical anatomy resources in the workplace. Method: This cross-sectional study used a postal survey sent to musculoskeletal outpatient physiotherapists in 64 Australian public hospitals. Survey questions examined demographics, qualifications, experience, types of resources used, whether resources meet requirements, and what improvements could be made to current resources. Results: A total of 193 physiotherapists responded (75% response rate; 60% female), of whom 49% were age 35 years or younger; 67% had only an undergraduate qualification, and 37% had practised for 5 years or less. More experienced physiotherapists used resources significantly less frequently ([odds ratio]=1.35; 95% CI, 1.17–1.57), and we found no significant associations between preference for online versus printed resources and age, sex, qualifications, or experience. Trends included less experienced physiotherapists identifying the absence of online access as a barrier to resource use and provision of improved online facilities as necessary to improve access to clinical anatomy resources. Conclusion: Results indicate distinct trends in physiotherapists' use of clinical anatomy resources, including a desire for improved online resource access on the part of less experienced physiotherapists. The findings are relevant to hospital outpatient clinics, particularly those that employ less experienced physiotherapists. PMID:26839457
Cheng, Adam; Donoghue, Aaron; Gilfoyle, Elaine; Eppich, Walter
2012-03-01
To review the essential elements of crisis resource management and provide a resource for instructors by describing how to use simulation-based training to teach crisis resource management principles in pediatric acute care contexts. A MEDLINE-based literature source. OUTLINE OF REVIEW: This review is divided into three main sections: Background, Principles of Crisis Resource Management, and Tools and Resources. The background section provides the brief history and definition of crisis resource management. The next section describes all the essential elements of crisis resource management, including leadership and followership, communication, teamwork, resource use, and situational awareness. This is followed by a review of evidence supporting the use of simulation-based crisis resource management training in health care. The last section provides the resources necessary to develop crisis resource management training using a simulation-based approach. This includes a description of how to design pediatric simulation scenarios, how to effectively debrief, and a list of potential assessment tools that instructors can use to evaluate crisis resource management performance during simulation-based training. Crisis resource management principles form the foundation for efficient team functioning and subsequent error reduction in high-stakes environments such as acute care pediatrics. Effective instructor training is required for those programs wishing to teach these principles using simulation-based learning. Dissemination and integration of these principles into pediatric critical care practice has the potential for a tremendous impact on patient safety and outcomes.
Sources and Resources for Teaching about Ancient Italy.
ERIC Educational Resources Information Center
Dutra, John A.
1979-01-01
Annotates sources and resources to use in teaching secondary students about ancient Roman history, including pedagogical guides, books on various aspects of Roman civilization, reference works, journals, audiovisual and related resources, and organizations. (Author/CK)
Grid Data and Tools | Grid Modernization | NREL
technologies and strategies, including renewable resource data sets and models of the electric power system . Renewable Resource Data A library of resource information to inform the design of efficient, integrated
A Review of Barriers to and Opportunities for the Integration of Renewable Energy in the Southeast
DOE Office of Scientific and Technical Information (OSTI.GOV)
McConnell, Ben W; Hadley, Stanton W; Xu, Yan
2011-08-01
The objectives of this study were to prepare a summary report that examines the opportunities for and obstacles to the integration of renewable energy resources in the Southeast between now and the year 2030. The report, which is based on a review of existing literature regarding renewable resources in the Southeast, includes the following renewable energy resources: wind, solar, hydro, geothermal, biomass, and tidal. The evaluation was conducted by the Oak Ridge National Laboratory for the Energy Foundation and is a subjective review with limited detailed analysis. However, the report offers a best estimate of the magnitude, time frame, andmore » cost of deployment of renewable resources in the Southeast based upon the literature reviewed and reasonable engineering and economic estimates. For the purposes of this report, the Southeast is defined as the states of Alabama, Arkansas, Florida, Georgia, Kentucky, Louisiana, Mississippi, North Carolina, South Carolina, Tennessee, Virginia, and West Virginia. In addition, some aspects of the report (wind and geothermal) also consider the extended Southeast, which includes Maryland, Missouri, Oklahoma, and Texas. A description of the existing base of renewable electricity installations in the region is given for each technology considered. Where available, the possible barriers and other considerations regarding renewable energy resources are listed in terms of availability, investment and maintenance costs, reliability, installation requirements, policies, and energy market. As stated above, the report is a comprehensive review of renewable energy resources in the southeastern region of United States based on a literature study that included information obtained from the Southern Bio-Power wiki, sources from the Energy Foundation, sources available to ORNL, and sources found during the review. The report consists of an executive summary, this introductory chapter describing report objectives, a chapter on analysis methods and the status of renewable resources, chapters devoted to each identified renewable resource, and a brief summary chapter. Chapter 2 on analysis methods and status summarizes the benefits of integrating renewable energy resources in the Southeast. The utilization of the existing fuels, both the fossil fuels and the renewable energy resources, is evaluated. The financial rewards of renewable resources are listed, which includes the amount of fuel imported from outside the Southeast to find the net benefit of local renewable generation, and both the typical and new green job opportunities that arise from renewable generation in the Southeast. With the load growth in the Southeast, the growth of transmission and fossil fuel generation may not meet the growing demands for energy. The load growth is estimated, and the benefits of renewable resources for solving local growing energy demands are evaluated. Chapters 3-7 discuss the key renewable energy resources in the Southeast. Six resources available in this region that are discussed are (1) wind, including both onshore and offshore; (2) solar, including passive, photovoltaic, and concentrating; (3) biomass energy, including switchgrass, biomass co-firing, wood, woody biomass, wood industry by-products (harvesting residues, mill waste, etc.), agricultural byproducts, landfill gas to energy and anaerobic digester gas; (4) hydro; and (5) geothermal. Because of limited development, ocean wave and tidal were not considered to be available in significant quantity before 2030 and are not presented in the final analysis. Estimates on the location of potential megawatt generation from these renewable resources in the Southeast are made. Each chapter will describe the existing base of the renewable electricity installations in the region now and, when available, the base of the existing manufacturing capacity in the region for renewable energy resources hardware and software. The possible barriers and considerations for renewable energy resources are presented.« less
Development of Internet algorithms and some calculations of power plant COP
NASA Astrophysics Data System (ADS)
Ustjuzhanin, E. E.; Ochkov, V. F.; Znamensky, V. E.
2017-11-01
The authors have analyzed Internet resources containing information on some thermodynamic properties of technically important substances (the water, the air etc.). There are considered databases those possess such resources and are hosted in organizations (Joint Institute for High Temperatures (Russian Academy of Sciences), Standartinform (Russia), National Institute of Standards and Technology (USA), Institute for Thermal Physics (Siberian Branch of the Russian Academy of Sciences), etc.). Currently, a typical form is an Internet resource that includes a text file, for example, it is a file containing tabulated properties, R = (ρ, s, h…), here ρ - the density, s - the entropy, h - the enthalpy of a substance. It is known a small number of Internet resources those have the following characteristic. The resource allows a customer to realize a number of options, for example: i) to enter the input data, Y = (p, T), here p - the pressure, T - the temperature, ii) to calculate R property using “an exe-file” program, iii) to copy the result X = (p, T, ρ, h, s, …). Recently, some researchers (including the authors of this report) have requested a software (SW) that is designed for R property calculations and has a form of an open interactive (OI) Internet resource (“a client function”, “template”). A computing part of OI resource is linked: 1) with a formula, which is applied to calculate R property, 2) with a Mathcad program, Code_1(R,Y). An interactive part of OI resource is based on Informatics and Internet technologies. We have proposed some methods and tools those are related to this part and let us: a) to post OI resource on a remote server, b) to link a client PC with the remote server, c) to implement a number of options to clients. Among these options, there are: i) to calculate R property at given Y arguments, ii) to copy mathematical formulas, iii) to copy Code_1(R,Y) as a whole. We have developed some OI - resources those are focused on sharing: a) SW that is used to design power plants, for an example, Code - GTP_1(Z,R,Y) and b) client functions those are aimed to determine R properties of the working fluid at fixed points of the thermodynamic cycle. The program let us calculate energy criteria, Z, including the internal coefficient of performance (COP) for a power plant. We have discussed OI resources, among them OI resource that includes Code - GTP_1(Z,R,Y) and connected with a complex power plant included: i) several gas turbines, i) several compressors etc.
Staff Development Resources, 1989-90. ITV Connection.
ERIC Educational Resources Information Center
South Carolina State Dept. of Education, Columbia. Office of Instructional Technology.
This staff development resource guide includes listings of television and radio broadcasts categorized by topical emphasis. Television program topics include: administration; adult education; arts; career education; certificate-renewal credit courses; college credit courses; computer education and new technology; custodial training; early…
Code of Federal Regulations, 2013 CFR
2013-01-01
... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT FEDERAL...) of the act, respectively, and include, but are not limited to, public access, recreation, fishing.... Biological and physical resources include, but are not limited to, air, tidal and nontidal wetlands, ocean...
Geological Survey research 1976
,
1976-01-01
This U.S. Geological Survey activities report includes a summary of recent (1976 fiscal year) scientific and economic results accompanied by a list of geologic and hydrologic investigations in progress and a report on the status of topographic mapping. The summary of results includes: (1) Mineral resources, Water resources, (2) Engineering geology and hydrology, (3) Regional geology, (4) Principles and processes, (5) Laboratory and field methods, (6) Topographic surveys and mapping, (7) Management of resources on public lands, (8) Land information and analysis, and (9) Investigations in other countries. Also included are lists of cooperating agencies and Geological Survey offices. (Woodard-USGS)
30 CFR 285.701 - What must I include in my Facility Design Report?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my Facility Design Report? 285.701 Section 285.701 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... Design, Fabrication, and Installation Reports § 285.701 What must I include in my Facility Design Report...
30 CFR 285.645 - What must I include in my GAP?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my GAP? 285.645 Section 285.645 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE... Requirements Contents of the General Activities Plan § 285.645 What must I include in my GAP? (a) You must...
30 CFR 285.610 - What must I include in my SAP?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my SAP? 285.610 Section 285.610 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE... Requirements Contents of the Site Assessment Plan § 285.610 What must I include in my SAP? Your SAP must...
Oil for health in sub-Saharan Africa: health systems in a 'resource curse' environment.
Calain, Philippe
2008-10-21
In a restricted sense, the resource curse is a theory that explains the inverse relationship classically seen between dependence on natural resources and economic growth. It defines a peculiar economic and political environment, epitomized by oil extraction in sub-Saharan Africa. Based on secondary research and illustrations from four oil-rich geographical areas (the Niger Delta region of Nigeria, Angola, southern Chad, Southern Sudan), I propose a framework for analysing the effects of the resource curse on the structure of health systems at sub-national levels. Qualitative attributes are emphasised. The role of the corporate sector, the influence of conflicts, and the value of classical mitigation measures (such as health impact assessments) are further examined. Health systems in a resource curse environment are classically fractured into tripartite components, including governmental health agencies, non-profit non-governmental organisations, and the corporate extractive sector. The three components entertain a range of contractual relationships generally based on operational considerations which are withdrawn from social or community values. Characterisation of agencies in this system should also include: values, operating principles, legitimacy and operational spaces. From this approach, it appears that community health is at the same time marginalized and instrumentalized toward economic and corporate interests in resource curse settings. From a public health point of view, the resource curse represents a fundamental failure of dominant development theories, rather than a delay in creating the proper economy and governance environment for social progress. The scope of research on the resource curse should be broadened to include more accurate or comprehensive indicators of destitution (including health components) and more open perspectives on causal mechanisms.
Oil for health in sub-Saharan Africa: health systems in a 'resource curse' environment
Calain, Philippe
2008-01-01
Background In a restricted sense, the resource curse is a theory that explains the inverse relationship classically seen between dependence on natural resources and economic growth. It defines a peculiar economic and political environment, epitomised by oil extraction in sub-Saharan Africa. Methods Based on secondary research and illustrations from four oil-rich geographical areas (the Niger Delta region of Nigeria, Angola, southern Chad, Southern Sudan), I propose a framework for analysing the effects of the resource curse on the structure of health systems at sub-national levels. Qualitative attributes are emphasised. The role of the corporate sector, the influence of conflicts, and the value of classical mitigation measures (such as health impact assessments) are further examined. Results Health systems in a resource curse environment are classically fractured into tripartite components, including governmental health agencies, non-profit non-governmental organisations, and the corporate extractive sector. The three components entertain a range of contractual relationships generally based on operational considerations which are withdrawn from social or community values. Characterisation of agencies in this system should also include: values, operating principles, legitimacy and operational spaces. From this approach, it appears that community health is at the same time marginalised and instrumentalised toward economic and corporate interests in resource curse settings. Conclusion From a public health point of view, the resource curse represents a fundamental failure of dominant development theories, rather than a delay in creating the proper economy and governance environment for social progress. The scope of research on the resource curse should be broadened to include more accurate or comprehensive indicators of destitution (including health components) and more open perspectives on causal mechanisms. PMID:18939986
Wymbs, Brian T
2018-06-01
Adults with attention-deficit hyperactivity disorder (ADHD) have more conflictual relations with their romantic partners than adults without ADHD. This study investigated whether adults with ADHD are differentially susceptible to conflict when self-control resources are depleted. Heterosexual adult couples (20 including at least one adult with ADHD; 12 including no adults with ADHD) were randomly assigned to have resources temporarily depleted or not. Positive and negative communication was assessed during a subsequent problem-solving task with their partners. Adults with ADHD whose self-control resources were depleted communicated less positively and more negatively with their romantic partners than adults without ADHD whose resources were depleted. Adults with ADHD appear to have a differential susceptibility to interpartner discord when their self-control resources have been depleted. Clinicians seeking to remediate discordant romantic relationships of adults with ADHD should consider evaluating how often their resources needed to manage their impulses are depleted.
ERIC Educational Resources Information Center
Hill, Margaret; Benoit, Robert
1998-01-01
Reviews the resources available for social studies teachers from the Schools of California Online Resources for Education (SCORE): History Social Science World Wide Web site. Includes curriculum-aligned resources and lessons; standards and assessment information; interactive projects and field trips; teacher chat area; professional development…
ERIC Educational Resources Information Center
Jarboe, Darren H.
2012-01-01
In 2007, a Virtual Education Center for Biorenewable Resources was initiated (Raman, Brown, Brumm, Anex, Euken, Nokes, Crofcheck, Van Gerpen, and He, 2006). The Center offered three courses through distance education, including Biorenewable Resources and Technology (BRT) 501--Fundamentals of Biorenewable Resources and Technology. The main…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-13
... included in the San Luis Resource Area Travel Management Plan (TMP), approved on June 4, 2009. These... Luis Resource Area Travel Management Plan'' in the subject line). FOR FURTHER INFORMATION CONTACT... Resource Valley Travel Management Plan and Amend San Luis Valley Resource Management Plan and Start the...
Developing a Resource Center in Consumer Education: An Annotated Bibliography.
ERIC Educational Resources Information Center
Garman, E. Thomas; And Others
The rationale behind this annotated bibliography of over 1300 items is that every consumer education teacher needs numerous classroom resources to provide for the individual needs of his students, and these resources should be balanced in representing all content areas. The resource materials included, mostly booklets and pamphlets for classroom…
Where To Get Resource Materials To Address Barriers to Learning. A Resource Packet.
ERIC Educational Resources Information Center
California Univ., Los Angeles. Center for Mental Health in Schools.
This resource aid is designed to provide a sampling of organizations and publishers that offer a variety of materials relevant to addressing students' psychosocial and mental concerns. Included is information about resources available upon request and/or purchase. The packet is divided into three sections. Section 1 identifies national…
Soil conservation service landscape resource management
Sally Schauman; Carolyn Adams
1979-01-01
SCS Landscape Resource Management (LRM) is the application of landscape architecture to SCS conservation activities. LRM includes but is not limited to visual resource management. LRM can be summarized in three principles: (1) SCS landscape architecture considers the landscape as a composite of ecological, social and visual resources; (2) SCS landscapes exist in the...
“Big Data” for breast cancer: where to look and what you will find
Clare, Susan E; Shaw, Pamela L
2016-01-01
Accessing the massive amount of breast cancer data that are currently publicly available may seem daunting to the brand new graduate student embarking on his/her first project or even to the seasoned lab leader, who may wish to explore a new avenue of investigation. In this review, we provide an overview of data resources focusing on high-throughput data and on cancer-related data resources. Although not intended as an exhaustive list, the information included in this review will provide a jumping-off point with descriptions of and links to the various data resources of interest. The review is divided into six sections: (1) compendia of data resources; (2) biomolecular repository “Hubs”; (3) a list of cancer-related data resources, which provides information on contents of the resource and whether the resource enables upload and analysis of investigator provided data; (4) a list of seminal publications containing specific breast cancer data, e.g., publications from METBRIC, Sanger, TCGA; (5) a list of journals focused on data science that include cancer-related “Big Data”; and (6) miscellaneous resources. PMID:28164152
Code of Federal Regulations, 2012 CFR
2012-01-01
..., animal, and related resources. This assistance may include conservation plan formulation, application... information on the conservation of soil, water, plant, animal, and related resources applicable specifically... Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF...
Code of Federal Regulations, 2013 CFR
2013-01-01
..., animal, and related resources. This assistance may include conservation plan formulation, application... information on the conservation of soil, water, plant, animal, and related resources applicable specifically... Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF...
Code of Federal Regulations, 2014 CFR
2014-01-01
..., animal, and related resources. This assistance may include conservation plan formulation, application... information on the conservation of soil, water, plant, animal, and related resources applicable specifically... Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF...
ERIC Educational Resources Information Center
Web Feet K-8, 2001
2001-01-01
This annotated subject guide to Web sites and additional resources focuses on mythology. Specific age levels are given for resources that include Web sites, CD-ROMs and software, videos, books, audios, and magazines; offers professional resources; and presents a relevant class activity. (LRW)
ERIC Educational Resources Information Center
Web Feet K-8, 2001
2001-01-01
This annotated subject guide to Web sites and additional resources focuses on space and astronomy. Specifies age levels for resources that include Web sites, CD-ROMS and software, videos, books, audios, and magazines; offers professional resources; and presents a relevant class activity. (LRW)
Continuous-variable quantum teleportation with non-Gaussian resources
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dell'Anno, F.; Dipartimento di Fisica, Universita degli Studi di Salerno, Via S. Allende, I-84081 Baronissi; CNR-INFM Coherentia, Napoli, Italy and CNISM Unita di Salerno and INFN Sezione di Napoli, Gruppo Collegato di Salerno, Baronissi
2007-08-15
We investigate continuous variable quantum teleportation using non-Gaussian states of the radiation field as entangled resources. We compare the performance of different classes of degaussified resources, including two-mode photon-added and two-mode photon-subtracted squeezed states. We then introduce a class of two-mode squeezed Bell-like states with one-parameter dependence for optimization. These states interpolate between and include as subcases different classes of degaussified resources. We show that optimized squeezed Bell-like resources yield a remarkable improvement in the fidelity of teleportation both for coherent and nonclassical input states. The investigation reveals that the optimal non-Gaussian resources for continuous variable teleportation are those thatmore » most closely realize the simultaneous maximization of the content of entanglement, the degree of affinity with the two-mode squeezed vacuum, and the, suitably measured, amount of non-Gaussianity.« less
Child health in low-resource settings: pathways through UK paediatric training.
Goenka, Anu; Magnus, Dan; Rehman, Tanya; Williams, Bhanu; Long, Andrew; Allen, Steve J
2013-11-01
UK doctors training in paediatrics benefit from experience of child health in low-resource settings. Institutions in low-resource settings reciprocally benefit from hosting UK trainees. A wide variety of opportunities exist for trainees working in low-resource settings including clinical work, research and the development of transferable skills in management, education and training. This article explores a range of pathways for UK trainees to develop experience in low-resource settings. It is important for trainees to start planning a robust rationale early for global child health activities via established pathways, in the interests of their own professional development as well as UK service provision. In the future, run-through paediatric training may include core elements of global child health, as well as designated 'tracks' for those wishing to develop their career in global child health further. Hands-on experience in low-resource settings is a critical component of these training initiatives.
Using NASA Products of the Water Cycle for Improved Water Resources Management
NASA Astrophysics Data System (ADS)
Toll, D. L.; Doorn, B.; Engman, E. T.; Lawford, R. G.
2010-12-01
NASA Water Resources works within the Earth sciences and GEO community to leverage investments of space-based observation and modeling results including components of the hydrologic cycle into water resources management decision support tools for the goal towards the sustainable use of water. These Earth science hydrologic related observations and modeling products provide a huge volume of valuable data in both near-real-time and extended back nearly 50 years. Observations of this type enable assessment of numerous water resources management issues including water scarcity, extreme events of drought and floods, and water quality. Examples of water cycle estimates make towards the contributions to the water management community include snow cover and snowpack, soil moisture, evapotranspiration, precipitation, streamflow and ground water. The availability of water is also contingent on the quality of water and hence water quality is an important part of NASA Water Resources. Water quality activities include both nonpoint source (agriculture land use, ecosystem disturbances, impervious surfaces, etc.) and direct remote sensing ( i.e., turbidity, algae, aquatic vegetation, temperature, etc.). . The NASA Water Resources Program organizes its projects under five functional themes: 1) stream-flow and flood forecasting; 2) water consumptive use and irrigation (includes evapotranspiration); 3) drought; 4) water quality; and 5) climate impacts on water resources. Currently NASA Water Resources is supporting 21 funded projects with 11 additional projects being concluded. To maximize the use of NASA water cycle measurements end to projects are supported with strong links with decision support systems. The NASA Water Resources Program works closely with other government agencies NOAA, USDA-FAS, USGS, AFWA, USAID, universities, and non-profit, international, and private sector organizations. International water cycle applications include: 1) Famine Early Warning System Network (FEWSNET) being expanded for famine relief to many developing nations of the world using a NASA Land Data Assimilation System (LDAS); 2) Air Force Weather Agency (AFWA) global hydrology mapping program that extends their global hydrology to much finer resolutions through use of an optimized LDAS; 3) 'SERVIR' a visualization and monitoring center of Earth science information in Central America and East Africa with plans for additional locations in developing countries of the world; 4) installing NASA Water Information System Platforms (WISPs) strategically located throughout the Middle East and North Africa (MENA) in partnerships with USAID and the World Bank; and 5) Latin American capacity building efforts within GEO.
ERIC Educational Resources Information Center
Jackson, Mary E.
2002-01-01
Explains portals as tools that gather a variety of electronic information resources, including local library resources, into a single Web page. Highlights include cross-database searching; integration with university portals and course management software; the ARL (Association of Research Libraries) Scholars Portal Initiative; and selected vendors…
Technology Systems. Laboratory Activities.
ERIC Educational Resources Information Center
Brame, Ray; And Others
This guide contains 43 modules of laboratory activities for technology education courses. Each module includes an instructor's resource sheet and the student laboratory activity. Instructor's resource sheets include some or all of the following elements: module number, course title, activity topic, estimated time, essential elements, objectives,…
Schools Inc.: An Administrator's Guide to the Business of Education.
ERIC Educational Resources Information Center
McCarthy, Bob; And Others
1989-01-01
This theme issue describes ways in which educational administrators are successfully automating many of their administrative tasks. Articles focus on student management; office automation, including word processing, databases, and spreadsheets; human resources; support services, including supplies, textbooks, and learning resources; financial…
Profiling unauthorized natural resource users for better targeting of conservation interventions
Baker, Julia; Twinamatsiko, Medard; Milner‐Gulland, E.J.
2015-01-01
Abstract Unauthorized use of natural resources is a key threat to many protected areas. Approaches to reducing this threat include law enforcement and integrated conservation and development (ICD) projects, but for such ICDs to be targeted effectively, it is important to understand who is illegally using which natural resources and why. The nature of unauthorized behavior makes it difficult to ascertain this information through direct questioning. Bwindi Impenetrable National Park, Uganda, has many ICD projects, including authorizing some local people to use certain nontimber forest resources from the park. However, despite over 25 years of ICD, unauthorized resource use continues. We used household surveys, indirect questioning (unmatched count technique), and focus group discussions to generate profiles of authorized and unauthorized resource users and to explore motivations for unauthorized activity. Overall, unauthorized resource use was most common among people from poor households who lived closest to the park boundary and farthest from roads and trading centers. Other motivations for unauthorized resource use included crop raiding by wild animals, inequity of revenue sharing, and lack of employment, factors that created resentment among the poorest communities. In some communities, benefits obtained from ICD were reported to be the greatest deterrents against unauthorized activity, although law enforcement ranked highest overall. Despite the sensitive nature of exploring unauthorized resource use, management‐relevant insights into the profiles and motivations of unauthorized resource users can be gained from a combination of survey techniques, as adopted here. To reduce unauthorized activity at Bwindi, we suggest ICD benefit the poorest people living in remote areas and near the park boundary by providing affordable alternative sources of forest products and addressing crop raiding. To prevent resentment from driving further unauthorized activity, ICDs should be managed transparently and equitably. PMID:26238261
Resources, stressors and psychological distress among older adults in Chennai, India.
Chokkanathan, Srinivasan
2009-01-01
Scant information exists on the complex interaction between resources and stressors and their subsequent influence on the psychological distress of older adults in India. Within the framework of resource theory, the present study examined the various pathways through which resources and stressors influence psychological distress by testing four models - the independence model, the stress-suppression model, the counteractive model and the resource-deterioration model. The independence model posits that resources and stressors have a direct relationship with psychological distress. The stress-suppression model hypothesizes that stressors mediate the influence of resources on psychological distress. The counteractive model postulates that stressors mobilize resources, which in turn influence psychological distress. The resource-deterioration model states that stressors deplete resources and subsequently exacerbate distress. In the present study, resources include social support, religiosity and mastery; stressors include life events, abuse and health problems. Psychological distress was measured using the Center for Epidemiological Studies Depression scale and Geriatric Depression Scale. Interviews were conducted among 400 adults aged 65 years and above, randomly selected from the electoral list of urban Chennai, India. The battery of instruments was translated into Tamil (local language) by back-translation. Structural Equation Modeling was conducted to test the three models. The results supported the stress-suppressor model. Resources had an indirect, negative relationship with psychological distress, and stressors had a direct, positive effect on distress. As such there is a need to identify and strengthen the resources available to older adults in India.
Ensembl Genomes 2016: more genomes, more complexity.
Kersey, Paul Julian; Allen, James E; Armean, Irina; Boddu, Sanjay; Bolt, Bruce J; Carvalho-Silva, Denise; Christensen, Mikkel; Davis, Paul; Falin, Lee J; Grabmueller, Christoph; Humphrey, Jay; Kerhornou, Arnaud; Khobova, Julia; Aranganathan, Naveen K; Langridge, Nicholas; Lowy, Ernesto; McDowall, Mark D; Maheswari, Uma; Nuhn, Michael; Ong, Chuang Kee; Overduin, Bert; Paulini, Michael; Pedro, Helder; Perry, Emily; Spudich, Giulietta; Tapanari, Electra; Walts, Brandon; Williams, Gareth; Tello-Ruiz, Marcela; Stein, Joshua; Wei, Sharon; Ware, Doreen; Bolser, Daniel M; Howe, Kevin L; Kulesha, Eugene; Lawson, Daniel; Maslen, Gareth; Staines, Daniel M
2016-01-04
Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of programmatic and interactive interfaces to a rich range of data including reference sequence, gene models, transcriptional data, genetic variation and comparative analysis. This paper provides an update to the previous publications about the resource, with a focus on recent developments. These include the development of new analyses and views to represent polyploid genomes (of which bread wheat is the primary exemplar); and the continued up-scaling of the resource, which now includes over 23 000 bacterial genomes, 400 fungal genomes and 100 protist genomes, in addition to 55 genomes from invertebrate metazoa and 39 genomes from plants. This dramatic increase in the number of included genomes is one part of a broader effort to automate the integration of archival data (genome sequence, but also associated RNA sequence data and variant calls) within the context of reference genomes and make it available through the Ensembl user interfaces. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.
Ensembl Genomes 2016: more genomes, more complexity
Kersey, Paul Julian; Allen, James E.; Armean, Irina; Boddu, Sanjay; Bolt, Bruce J.; Carvalho-Silva, Denise; Christensen, Mikkel; Davis, Paul; Falin, Lee J.; Grabmueller, Christoph; Humphrey, Jay; Kerhornou, Arnaud; Khobova, Julia; Aranganathan, Naveen K.; Langridge, Nicholas; Lowy, Ernesto; McDowall, Mark D.; Maheswari, Uma; Nuhn, Michael; Ong, Chuang Kee; Overduin, Bert; Paulini, Michael; Pedro, Helder; Perry, Emily; Spudich, Giulietta; Tapanari, Electra; Walts, Brandon; Williams, Gareth; Tello–Ruiz, Marcela; Stein, Joshua; Wei, Sharon; Ware, Doreen; Bolser, Daniel M.; Howe, Kevin L.; Kulesha, Eugene; Lawson, Daniel; Maslen, Gareth; Staines, Daniel M.
2016-01-01
Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of programmatic and interactive interfaces to a rich range of data including reference sequence, gene models, transcriptional data, genetic variation and comparative analysis. This paper provides an update to the previous publications about the resource, with a focus on recent developments. These include the development of new analyses and views to represent polyploid genomes (of which bread wheat is the primary exemplar); and the continued up-scaling of the resource, which now includes over 23 000 bacterial genomes, 400 fungal genomes and 100 protist genomes, in addition to 55 genomes from invertebrate metazoa and 39 genomes from plants. This dramatic increase in the number of included genomes is one part of a broader effort to automate the integration of archival data (genome sequence, but also associated RNA sequence data and variant calls) within the context of reference genomes and make it available through the Ensembl user interfaces. PMID:26578574
Rosenberg, A E
2000-01-01
This article describes the process involved in conducting a sample inventory of community-based sports, recreation/leisure, and arts resources that include children with physical disabilities in Monroe County, New York. The inventory instrument, Community Resource Inventory for Children with Physical Disabilities, was designed to examine organizational or group capacity to provide activities for children with physical disabilities. The inventory was administered by phone to organizations and groups identified as meeting the definition of a community-based resource. One hundred and six CBR informants were interviewed, each reporting one or two recreational activities provided at their site. The activities included arts, sports, or leisure offerings, with a total of 127 activities identified in the sample. The results of the study support the premise that community-based resources are receptive to providing activities for children with physical disabilities and to potential collaboration with therapists. Numerous barriers exixts, however, including environmental inaccessibility, lack of personnel training, and including environmental inaccesssbility, lack of personnel training, and costs of participation. The results suggest several educational and system-based changes that may promote future collaborative efforts between therapists and community-based organizations.
NASA Astrophysics Data System (ADS)
Robinson, Zoe; Whitfield, Stephen; Gertisser, Ralf; Krause, Stefan; McKay, Deirdre; Pringle, Jamie; Szkornik, Katie; Waller, Richard
2010-05-01
The UK's Higher Education Academy Subject Centre for Geography, Earth and Environmental Sciences (GEES) is currently running a project entitled ‘C-Change in GEES: Open licensing of climate change and sustainability resources in the Geography, Earth and Environmental Sciences' as part of a national Open Educational Resource project. The C-Change project aims to explore the challenges involved in ‘repurposing' existing teaching materials on the topics of climate change and sustainability to make them open access. This project has produced an open access resource of diverse climate change and sustainability-related teaching materials across the subjects of Geography, Earth and Environmental Sciences. The process of repurposing existing face-to-face teaching resources requires consideration of a wide variety of issues including the Intellectual Property Rights (IPR) associated with images and other material included in the teaching resources, in addition to issues of quality, accessibility and usability of resources. Open access education is an issue that will have implications across the whole of the organizational structure of a university, from legal advisors with commitments to University research and enterprise activities, to the academics wishing to produce open access resources, through to all levels of senior management. The attitudes, concerns and openness to Open Educational Resources of stakeholders from all positions within a HE institution will have implications for the participation of that institution within the OER movement. The many barriers to the whole-scale adoption of Open Educational Resources within the UK Higher Education system and the willingness of UK Higher Education Institutions to engage in the OER movement include institutional perspectives on the IPR of teaching materials developed by members of staff within the institution and financial viability, in addition to more sceptical attitudes of potential contributors. Keele University is one of seven academic partners in the C-Change project and researchers at Keele have produced open access resources across a wide variety of sustainability-related themes from reconstructing past environments (for example sea-level change); regional impacts of predicted climate change (for example implications to permafrost environments); through to strategies for a sustainable future, including topics on greening business and engineering solutions. The resources range from PowerPoint presentations to image banks, reading lists, and suggestions for classroom and coursework activities. These resources are designed to be useful for other higher education practitioners developing teaching resources in this area. This presentation will present the range of open access resources developed at Keele University in addition to the lessons learnt in repurposing resources for open access, and a summary of different attitudes within Higher Education Institutions towards the OER movement.
NASA Technical Reports Server (NTRS)
Rado, B. Q.
1975-01-01
Automatic classification techniques are described in relation to future information and natural resource planning systems with emphasis on application to Georgia resource management problems. The concept, design, and purpose of Georgia's statewide Resource AS Assessment Program is reviewed along with participation in a workshop at the Earth Resources Laboratory. Potential areas of application discussed include: agriculture, forestry, water resources, environmental planning, and geology.
NASA Technical Reports Server (NTRS)
1974-01-01
The potential of the space shuttle as a platform for captive earth resources payloads in the sortie mode, and as a launch and services vehicle for automated earth resources spacecraft is examined. The capabilities of the total space transportation system which are pertinent to earth resources sorties and automated spacecraft are included.
ERIC Educational Resources Information Center
England, Lenore; Fu, Li
2011-01-01
A critical part of electronic resources management, the electronic resources evaluation process is multi-faceted and includes a seemingly endless range of resources and tools involving numerous library staff. A solution is to build a Web site to bring all of the components together that can be implemented quickly and result in an organizational…
LiDAR Applications in Resource Geology and Benefits for Land Management
NASA Astrophysics Data System (ADS)
Mikulovsky, R. P.; De La Fuente, J. A.
2013-12-01
The US Forest Service (US Department of Agriculture) manages a broad range of geologic resources and hazards on National Forests and Grass Lands throughout the United States. Resources include rock and earth materials, groundwater, caves and paleontological resources, minerals, energy resources, and unique geologic areas. Hazards include landslides, floods, earthquakes, volcanic eruptions, and naturally hazardous materials (e.g., asbestos, radon). Forest Service Geologists who address these issues are Resource Geologists. They have been exploring LiDAR as a revolutionary tool to efficiently manage all of these hazards and resources. However, most LiDAR applications for management have focused on timber and fuels management, rather than landforms. This study shows the applications and preliminary results of using LiDAR for managing geologic resources and hazards on public lands. Applications shown include calculating sediment budgets, mapping and monitoring landslides, mapping and characterizing borrow pits or mines, determining landslide potential, mapping faults, and characterizing groundwater dependent ecosystems. LiDAR can be used to model potential locations of groundwater dependent ecosystems with threatened or endangered plant species such as Howellia aquatilis. This difficult to locate species typically exists on the Mendocino National Forest within sag ponds on landslide benches. LiDAR metrics of known sites are used to model potential habitat. Thus LiDAR can link the disciplines of geology, hydrology, botany, archaeology and others for enhanced land management. As LiDAR acquisition costs decrease and it becomes more accessible, land management organizations will find a wealth of applications with potential far-reaching benefits for managing geologic resources and hazards.
Web-Based Couple Interventions: Do They Have a Future?
Georgia, Emily J.; Doss, Brian D.
2015-01-01
To examine the current and potential future impact of formal and informal resources to enhance romantic relationships, 1,160 individuals were surveyed. When asked about resources previously utilized, participants reported that numerous forms of relationship help, including talking to a friend/coworker/family member, an individual therapist, and reading self-help materials had a larger impact than attending couple therapy. When asked about potential resources they would be likely to use in the future for relationship problems, participants indicated a strong preference for online self-help resources that included detailed feedback paired with a comprehensive, structured program. Implications for future development and dissemination are discussed. PMID:26550001
Project resources planning and control
NASA Technical Reports Server (NTRS)
Sibbers, C. W.
1984-01-01
This report contains instructional guidelines for the resources planning and control of research and development (R&D) projects managed by NASA's Langley Research Center (LaRC). Although written to serve primarily as a practical guide and reference for those LaRC personnel who perform resources planning, analysis, control, and reporting functions, it should also be meaningful to other NASA personnel who are directly or indirectly involved in or affected by these functions, especially project technical managers whose responsibilities include resources management. Certain sections should help Contractor personnel to better understand what resources information must usually be submitted on LaRC projects and what use is made of such information. The Project Manager of a large R&D project typicaly receives support from an Analyst in the area of resources management. The Analyst provides assistance in four functional areas: Planning, Analysis/Control, Administration, and Reporting. Each of these functions are discussed in detail. Examples of techniques used effectively on LaRC projects have been included where applicable. A considerable amount of information has been included on the use of Performance Measurement (Earned Value) Systems for contract cost control and reporting as little information is currently available on this subject in NASA publications.
Intergenerational resource transfers with random offspring numbers
Arrow, Kenneth J.; Levin, Simon A.
2009-01-01
A problem common to biology and economics is the transfer of resources from parents to children. We consider the issue under the assumption that the number of offspring is unknown and can be represented as a random variable. There are 3 basic assumptions. The first assumption is that a given body of resources can be divided into consumption (yielding satisfaction) and transfer to children. The second assumption is that the parents' welfare includes a concern for the welfare of their children; this is recursive in the sense that the children's welfares include concern for their children and so forth. However, the welfare of a child from a given consumption is counted somewhat differently (generally less) than that of the parent (the welfare of a child is “discounted”). The third assumption is that resources transferred may grow (or decline). In economic language, investment, including that in education or nutrition, is productive. Under suitable restrictions, precise formulas for the resulting allocation of resources are found, demonstrating that, depending on the shape of the utility curve, uncertainty regarding the number of offspring may or may not favor increased consumption. The results imply that wealth (stock of resources) will ultimately have a log-normal distribution. PMID:19617553
Fraser, Kimberly D; Estabrooks, Carole; Allen, Marion; Strang, Vicki
2009-03-01
Case managers make decisions that directly affect the amount and type of services home care clients receive and subsequently affect the overall available health care resources of home care programs. A recent systematic review of the literature identified significant knowledge gaps with respect to resource allocation decision-making in home care. Using Spradley's methodology, we designed an ethnographic study of a children's home care program in Western Canada. The sample included 11 case managers and program leaders. Data sources included interviews, card sorts, and participant observation over a 5-month period. Data analyses included open coding, domain, taxonomic, and componential analysis. One of the key findings was a taxonomy of factors that influence case manager resource allocation decisions. The factors were grouped into one of four main categories: system-related, home care program-related, family related, or client-related. Family related factors have not been previously reported as influencing case manager resource allocation decision-making and nor has the team's role been reported as an influencing factor. The findings of this study are examined in light of Daniels and Sabin's Accountability for Reasonableness framework, which may be useful for future knowledge development about micro-level resource allocation theory.
Carr, N.B.; Babel, N.; Diffendorfer, J.; Ignizio, D.; Hawkins, S.; Latysh, N.; Leib, K.; Linard, J.; Matherne, A.
2012-01-01
Throughout the western United States, increased demand for energy is driving the rapid development of oil, gas (including shale gas and coal-bed methane), and uranium, as well as renewable energy resources such as geothermal, solar, and wind. Much of the development in the West is occurring on public lands, including those under Federal and State jurisdictions. In Colorado and New Mexico, these public lands make up about 40 percent of the land area. Both states benefit from the revenue generated by energy production, but resource managers and other decisionmakers must balance the benefits of energy development with the potential consequences for ecosystems, recreation, and other resources. Although a substantial amount of geospatial data on existing energy development and energy potential is available, much of this information is not readily accessible to natural resource decisionmakers, policymakers, or the public. Furthermore, the data often exist in varied formats, requiring considerable processing before these datasets can be used to evaluate tradeoffs among resources, compare development alternatives, or quantify cumulative impacts. To allow for a comprehensive evaluation among different energy types, an interdisciplinary team of U.S. Geological Survey (USGS) scientists has developed an online Interactive Energy Atlas for Colorado and New Mexico. The Energy and Environment in the Rocky Mountain Area (EERMA) interdisciplinary team includes investigators from several USGS science centers1. The purpose of the EERMA Interactive Energy Atlas is to facilitate access to geospatial data related to energy resources, energy infrastructure, and natural resources that may be affected by energy development. The Atlas is designed to meet the needs of various users, including GIS analysts, resource managers, policymakers, and the public, who seek information about energy in the western United States. Currently, the Atlas has two primary capabilities, a GIS data viewer and an interactive map gallery.
Huang, Chiung-Yu; Perng, Shoa-Jen; Chen, Hisu-Fung; Lai, Chien-Yu
2008-12-01
It is well recognized that patients with diabetes encounter a host of daily self-care issues, including controlling blood sugar and preventing and managing complications, which impact significantly upon quality of life. Studies have indicated that learned resourcefulness has a potentially positive effect in dealing with psychosocial and health problems. The purpose of this study was to test the relationship between learned resourcefulness and quality of life in type II diabetic patients. The mediating and moderating effects of learned resourcefulness on the relationship between metabolic control and quality of life of diabetic patients was also examined. This cross-sectional and correlational study included a convenience sample of 131 type II diabetic patients recruited from three hospitals in southern Taiwan. Data were collected through questionnaires, which included the Rosenbaum's Self Control Schedule and World Health Organization's Quality of Life (Short Version). Multiple regression techniques were used to analyze outcome predictors. Study findings include identification of a mediating effect of learned resourcefulness between metabolic control and quality of life. While most DM patients were not satisfied with their health, we found that those with greater learned resourcefulness enjoyed a better quality of life. Learned resourcefulness, gender, and HbA1C explained 35.2% of variance in DM patient quality of life. Male diabetic patients enjoyed a better quality of life than females, even though levels of learned resourcefulness between the two groups were not significantly different. Results indicate that poor metabolic control of diabetic patients has a detrimental effect on quality of life, and when diabetic patients use more self-control skills, they may achieve better quality of life. Results suggest that nurses who use cognitive behavior coping strategies (resourcefulness) may help diabetic patients achieve better metabolic control and promote better quality of life.
Rogers Van Katwyk, Susan; Jones, Sara L; Hoffman, Steven J
2018-02-05
Antimicrobial resistance is an important global issue facing society. Healthcare workers need to be engaged in solving this problem, as advocates for rational antimicrobial use, stewards of sustainable effectiveness, and educators of their patients. To fulfill this role, healthcare workers need access to training and educational resources on antimicrobial resistance. To better understand the resources available to healthcare workers, we undertook a global environmental scan of educational programs and resources targeting healthcare workers on the topic of antimicrobial resistance and antimicrobial stewardship. Programs were identified through contact with key experts, web searching, and academic literature searching. We summarized programs in tabular form, including participating organizations, region, and intended audience. We developed a coding system to classify programs by program type and participating organization type, assigning multiple codes as necessary and creating summary charts for program types, organization types, and intended audience to illustrate the breadth of available resources. We identified 94 educational initiatives related to antimicrobial resistance and antimicrobial stewardship, which represent a diverse array of programs including courses, workshops, conferences, guidelines, public outreach materials, and online-resource websites. These resources were developed by a combination of government bodies, professional societies, universities, non-profit and community organizations, hospitals and healthcare centers, and insurance companies and industry. Most programs either targeted healthcare workers collectively or specifically targeted physicians. A smaller number of programs were aimed at other healthcare worker groups including pharmacists, nurses, midwives, and healthcare students. Our environmental scan shows that there are many organizations working to develop and share educational resources for healthcare workers on antimicrobial resistance and antimicrobial stewardship. Governments, hospitals, and professional societies appear to be driving action on this front, sometimes working with other types of organizations. A broad range of resources have been made freely available; however, we have noted several opportunities for action, including increased engagement with students, improvements to pre-service education, recognition of antimicrobial resistance courses as continuing medical education, and better platforms for resource-sharing online.
76 FR 25298 - Southwest Idaho Resource Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-04
... DEPARTMENT OF AGRICULTURE Forest Service Southwest Idaho Resource Advisory Committee AGENCY... Forests' Southwest Idaho Resource Advisory Committee will conduct a business meeting. The meeting is open... Operations Center, 108 Spring Street, Cascade, Idaho. SUPPLEMENTARY INFORMATION: Agenda topics will include...
Timber resources of the Sacramento area, California, 1972.
Brian R. Wall
1978-01-01
This report summarizes the 1972 timber resource inventory of the Sacramento area, California. Included are detailed tables of forest area, timber volume, growth, mortality, and timber cut and a discussion of the current timber resource and timber industry situation.
Crenna, Eleonora; Sozzo, Sara; Sala, Serenella
2018-01-20
Natural resources, biotic and abiotic, are fundamental from both the ecological and socio-economic point of view, being at the basis of life-support. However, since the demand for finite resources continues to increase, the sustainability of current production and consumption patterns is questioned both in developed and developing countries. A transition towards an economy based on biotic renewable resources (bio-economy) is considered necessary in order to support a steady provision of resources, representing an alternative to an economy based on fossil and abiotic resources. However, to ensure a sustainable use of biotic resources, there is the need of properly accounting for their use along supply chains as well as defining a robust and comprehensive impact assessment model. Since so far naturally occurring biotic resources have gained little attention in impact assessment methods, such as life cycle assessment, the aim of this study is to enable the inclusion of biotic resources in the assessment of products and supply chains. This paper puts forward a framework for biotic resources assessment, including: i) the definition of system boundaries between ecosphere and technosphere, namely between naturally occurring and man-made biotic resources; ii) a list of naturally occurring biotic resources which have a commercial value, as basis for building life cycle inventories (NOBR, e.g. wild animals, plants etc); iii) an impact pathway to identify potential impacts on both resource provision and ecosystem quality; iv) a renewability-based indicator (NOBRri) for the impact assessment of naturally occurring biotic resources, including a list of associated characterization factors. The study, building on a solid review of literature and of available statistical data, highlights and discusses the critical aspects and paradoxes related to biotic resource inclusion in LCA: from the system boundaries definition up to the resource characterization.
Autonomous Learner Model Resource Book
ERIC Educational Resources Information Center
Betts, George T.; Carey, Robin J.; Kapushion, Blanche M.
2016-01-01
"Autonomous Learner Model Resource Book" includes activities and strategies to support the development of autonomous learners. More than 40 activities are included, all geared to the emotional, social, cognitive, and physical development of students. Teachers may use these activities and strategies with the entire class, small groups, or…
Additional Resources - Naval Oceanography Portal
section Advanced Search... Sections Home Time Earth Orientation Astronomy Meteorology Oceanography Ice You , including research and development results. Includes Astronomy and Space, as well as Earth and Ocean Sciences subject categories. Astronomy Resources Union List of Astronomy Serials (ULAS) - Bibliographic
Information in the Water and Sanitation Sector.
ERIC Educational Resources Information Center
Rodda, John C.; And Others
1994-01-01
Includes 17 articles on aspects of collecting, managing, and disseminating data about the world's water supply and use. Topics addressed include United Nations agencies involved with water resources; management information systems; providing information needed by water resources professionals; and the role of regional organizations in providing…
43 CFR 10005.14 - Resource features applicable to the plan.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Habitat, including: (1) Protection of existing wetlands, (2) Restoration of drained or otherwise degraded wetlands, (3) Enhancement of wetland habitat. (f) Upland Habitat, including: (1) Protection or restoration... and/or recreation resources. Biological projects may focus on the protection or restoration of an...
From the Fur Trade to Acid Rain: A Study of Canadian Natural Resources.
ERIC Educational Resources Information Center
Winans, Linda
1988-01-01
Presents a teaching module for upper elementary students that devotes eight class periods of study to Canadian resources. Includes study of the Canadian fur trade, fishing industry, forestry, and the problems caused by acid rain. Includes the unit evaluation. (DB)
Shaping the Electronic Library--The UW-Madison Approach.
ERIC Educational Resources Information Center
Dean, Charles W., Ed.; Frazier, Ken; Pope, Nolan F.; Gorman, Peter C.; Dentinger, Sue; Boston, Jeanne; Phillips, Hugh; Daggett, Steven C.; Lundquist, Mitch; McClung, Mark; Riley, Curran; Allan, Craig; Waugh, David
1998-01-01
This special theme section describes the University of Wisconsin-Madison's experience building its Electronic Library. Highlights include integrating resources and services; the administrative framework; the public electronic library, including electronic publishing capability and access to World Wide Web-based and other electronic resources;…
Astronomical Resources. The Solar System: An Introductory Bibliography.
ERIC Educational Resources Information Center
Fraknoi, Andrew
This reference surveys resources of astronomical information including books and articles about the solar system, Mercury, Venus, Earth, the Moon, Mars, Jupiter, Saturn, Uranus, Neptune, Pluto, Asteroids, Comets, and Meteors. Also included is a list of seven available slide sets about the solar system. (CW)
30 CFR 253.41 - What terms must I include in my OSFR evidence?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What terms must I include in my OSFR evidence? 253.41 Section 253.41 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL SPILL FINANCIAL RESPONSIBILITY FOR OFFSHORE FACILITIES Requirements for Submitting OSFR Information § 253.41 What terms must I include in my...
30 CFR 254.22 - What information must I include in the “Introduction and plan contents” section?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What information must I include in the âIntroduction and plan contentsâ section? 254.22 Section 254.22 Mineral Resources MINERALS MANAGEMENT SERVICE... must I include in the “Introduction and plan contents” section? The “Introduction and plan contents...
30 CFR 254.22 - What information must I include in the “Introduction and plan contents” section?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What information must I include in the âIntroduction and plan contentsâ section? 254.22 Section 254.22 Mineral Resources BUREAU OF OCEAN ENERGY... Facilities § 254.22 What information must I include in the “Introduction and plan contents” section? The...
Geology and assessment of unconventional resources of Phitsanulok Basin, Thailand
,
2014-01-01
The U.S. Geological Survey (USGS) quantitatively assessed the potential for unconventional oil and gas resources within the Phitsanulok Basin of Thailand. Unconventional resources for the USGS include shale gas, shale oil, tight gas, tight oil, and coalbed gas. In the Phitsanulok Basin, only potential shale-oil and shale-gas resources were quantitatively assessed.
Resource Rivalry in the Third World,
1984-03-31
and specifically includes comparative NATO/Warsaw Pact dependence on critical resources , externally supplied ; determination of the extent, ways and...essential, especially defense-related, industry, the nation thereby becoming significantly dependent on the supplies of such resource from foreign...8217 consequences; 2. lac’. of adequate domestic resources ; 3. lim- ited potential for suitable substitute materials; and 4. lack of alternative sources
ERIC Educational Resources Information Center
Stephens, Wayne E.; And Others
Designed to provide data and resource materials needed by the Menominee Restoration Committee and others involved in reservation organizational and development planning, this report covers the present status of the Menominee tribal resources and presents an annotated bibliography. The resource inventory includes maps, tables, and charts and is…
The Use of Electronic Resources by Academic Staff at the University of Ilorin, Nigeria
ERIC Educational Resources Information Center
Tella, Adeyinka; Orim, Faith; Ibrahim, Dauda Morenikeji; Memudu, Suleiman Ajala
2018-01-01
The use of e-resources is now commonplace among academics in tertiary educational institutions the world over. Many academics including those in the universities are exploring the opportunities of e-resources to facilitate teaching and research. As the use of e-resources is increasing particularly among academics at the University of Ilorin,…
Timber resource statistics for the Sacramento resource area of California.
Karen L. Waddell; Patricia M. Bassett
1997-01-01
This report is a summary of timber resource statistics for the Sacramento Resource Area of California, which includes Butte, Colusa, El Dorado, Glenn, Lake, Napa, Nevada, Placer, Plumas, Sacramento, Sierra, Sutter, Tehama, Yolo, and Yuba Counties. Data were collected as part of a statewide multiresource inventory. The inventory sampled private and public lands except...
Effects of fire management of southwestern natural resources
J. S. Krammes
1990-01-01
The proceedings is a collection of papers and posters presented at the Symposium on Effects of Fire Management of Southwestern Natural Resources held in Tucson, Arizona, November 15-17, 1988. Included are papers, poster papers and a comprehensive list of references on the effects of fire on: plant succession, cultural resources, hydrology, range and wildlife resources...
ERIC Educational Resources Information Center
Walters, Kirk; Smith, Toni; Leinwand, Steve; Ford, Jennifer; Scheopner Torres, Aubrey
2015-01-01
This study was designed in response to a request from rural educators in the Northeast for support in identifying high-quality online resources to implement the Common Core State Standards for Mathematics (CCSSM). The process for identifying online resources included selecting resources that had an easily navigable CCSSM organizational structure…
10 CFR 960.4-2-8-1 - Natural resources.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 4 2013-01-01 2013-01-01 false Natural resources. 960.4-2-8-1 Section 960.4-2-8-1 Energy... REPOSITORY Postclosure Guidelines § 960.4-2-8-1 Natural resources. (a) Qualifying condition. This site shall..., scarcity, and technology—the natural resources, including ground water suitable for crop irrigation or...
10 CFR 960.4-2-8-1 - Natural resources.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 4 2012-01-01 2012-01-01 false Natural resources. 960.4-2-8-1 Section 960.4-2-8-1 Energy... REPOSITORY Postclosure Guidelines § 960.4-2-8-1 Natural resources. (a) Qualifying condition. This site shall..., scarcity, and technology—the natural resources, including ground water suitable for crop irrigation or...
10 CFR 960.4-2-8-1 - Natural resources.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 10 Energy 4 2014-01-01 2014-01-01 false Natural resources. 960.4-2-8-1 Section 960.4-2-8-1 Energy... REPOSITORY Postclosure Guidelines § 960.4-2-8-1 Natural resources. (a) Qualifying condition. This site shall..., scarcity, and technology—the natural resources, including ground water suitable for crop irrigation or...
ERIC Educational Resources Information Center
Voydanoff, Patricia
2005-01-01
Using person-environment fit theory, this article formulates a conceptual model that links work, family, and boundary-spanning demands and resources to work and family role performance and quality. Linking mechanisms include 2 dimensions of perceived work-family fit (work demands--family resources fit and family demands--work resources fit) and a…
Resources on Law-Related Education: Documents and Journal Articles in ERIC. Yearbook No. 3.
ERIC Educational Resources Information Center
Healy, Langdon T., Ed.; Vontz, Thomas S., Ed.
This ERIC resource is a guide to the array of law-related education (LRE) resources available to teachers. The annotated bibliography offers resources for essential knowledge of the law, innovative teaching methods, and guides to national LRE programs. Included in this collection are abstracts of LRE documents and journal articles, arranged…
Timber resource statistics for the San Joaquin and southern resource areas of California.
Karen L. Waddell; Patricia M. Bassett
1997-01-01
This report is a summary of timber resource statistics for the San Joaquin and Southern Resource Areas of California, which include Alpine, Amador, Calaveras, Fresno, Imperial, Inyo, Kern, Kings, Los Angeles, Madera, Mariposa, Merced, Mono, Orange, Riverside, San Bernardino, San Diego, San Joaquin, Stanislaus, Tulare, and Tuolumne Counties. Data were collected as part...
ERIC Educational Resources Information Center
Rettig, Heike, Ed.
This proceedings contains papers from the first European seminar of the Trans-European Language Resources Infrastructure (TELRI) include: "Cooperation with Central and Eastern Europe in Language Engineering" (Poul Andersen); "Language Technology and Language Resources in China" (Feng Zhiwei); "Public Domain Generic Tools:…
ERIC Educational Resources Information Center
Alocer, Josep Garcia
1993-01-01
Describes the implementation of a training course in computerized educational resource management provided for staff of Pedagogical Resource Centres in Catalonia (Spain). Training in telematics is explained, including documentary training and an ongoing process of permanent training assistance; the telematics infrastructure is discussed; and the…
Timber resource statistics for the north interior resource area of California.
Karen L. Waddell; Patricia M. Bassett
1997-01-01
This report is a summary of timber resource statistics for the North Interior Resource Area of California, which includes Lassen, Modoc, Shasta, Siskiyou, and Trinity Counties. Data were collected as part of a statewide multiresource inventory. The inventory sampled private and public lands except reserved areas and National Forests. The National Forest System provided...
10 CFR 960.4-2-8-1 - Natural resources.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 4 2011-01-01 2011-01-01 false Natural resources. 960.4-2-8-1 Section 960.4-2-8-1 Energy... REPOSITORY Postclosure Guidelines § 960.4-2-8-1 Natural resources. (a) Qualifying condition. This site shall..., scarcity, and technology—the natural resources, including ground water suitable for crop irrigation or...
ERIC Educational Resources Information Center
Virginia State Dept. of Education, Richmond.
This resource handbook, which is designed for use by instructors of courses in advanced marketing, consists of a duty/task list with referenced resources, a duty/task list with learning activities, and a list of resources. Included in each list are materials dealing with the following topics: communication in marketing, economics in marketing,…
75 FR 63436 - Glenn/Colusa County Resource Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-15
... DEPARTMENT OF AGRICULTURE Forest Service Glenn/Colusa County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Glenn/Colusa County Resource Advisory Committee (RAC) will meet in Willows, California. Agenda items covered include: (1) Introductions, (2...
75 FR 27287 - Glenn/Colusa County Resource Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-14
... DEPARTMENT OF AGRICULTURE Forest Service Glenn/Colusa County Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Glenn/Colusa County Resource Advisory Committee (RAC) will meet in Willows, California. Agenda items covered include: (1) Introductions, (2...
Dave Sperling's Guide to the Internet's Best Writing Resources.
ERIC Educational Resources Information Center
Sperling, Dave
2003-01-01
Provides a guide to writing resources on the Internet, including resources for business writing, dictionaries and thesauruses, e-mail, encyclopedias, free Web space, grammar, fun, online help, online writing labs, punctuation, and spelling. Lists useful Internet tips. (Author/VWL)
Timber resources of northern interior California, 1970.
Charles L. Bolsinger
1976-01-01
This report summarizes a timber resource inventory in Lassen, Modoc, Siskiyou, Shasta, and Trinity Counties, California. Included are detailed tables of forest area, timber volume, growth, mortality, and removals and a discussion of the current timber resource and timber industry situation.
76 FR 770 - Mendocino Resource Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-06
... DEPARTMENT OF AGRICULTURE Forest Service Mendocino Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Mendocino County Resource Advisory Committee will meet January 21, 2011 (RAC) in Willits, California. Agenda items to be covered include: (1) Approval of...
75 FR 3197 - Mendocino Resource Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-20
... DEPARTMENT OF AGRICULTURE Forest Service Mendocino Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Mendocino County Resource Advisory Committee will meet February 5, 2010 (RAC) in Willits, California. Agenda items to be covered include: (1) Approval of...
76 FR 16378 - Mendocino Resource Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-23
... DEPARTMENT OF AGRICULTURE Forest Service Mendocino Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Mendocino County Resource Advisory Committee will meet April 15, 2011 (RAC) in Willits, California. Agenda items to be covered include: (1) Approval of...
77 FR 56607 - Mendocino Resource Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-13
... DEPARTMENT OF AGRICULTURE Forest Service Mendocino Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Mendocino County Resource Advisory Committee will meet September 21, 2012 (RAC) in Willits, California. Agenda items to be covered include: (1) Approval...
75 FR 27704 - Mendocino Resource Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-18
... DEPARTMENT OF AGRICULTURE Forest Service Mendocino Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Mendocino County Resource Advisory Committee will meet June 18, 2010 (RAC) in Willits, California. Agenda items to be covered include: (1) Approval of...
DOT National Transportation Integrated Search
2007-01-01
At present, there are no clear guidelines for identifying and managing the wide variety of cultural resources within the Virginia Department of Transportation (VDOT) highway rights of way. These resources include such elements as archaeological sites...
Resources for Teaching Astronomy.
ERIC Educational Resources Information Center
Grafton, Teresa; Suggett, Martin
1991-01-01
Resources that are available for teachers presenting astronomy in the National Curriculum are listed. Included are societies and organizations, resource centers and places to visit, planetaria, telescopes and binoculars, planispheres, star charts, night sky diaries, equipment, audiovisual materials, computer software, books, and magazines. (KR)
Systems and methods for automatically identifying and linking names in digital resources
Parker, Charles T.; Lyons, Catherine M.; Roston, Gerald P.; Garrity, George M.
2017-06-06
The present invention provides systems and methods for automatically identifying name-like-strings in digital resources, matching these name-like-string against a set of names held in an expertly curated database, and for those name-like-strings found in said database, enhancing the content by associating additional matter with the name, wherein said matter includes information about the names that is held within said database and pointers to other digital resources which include the same name and it synonyms.
30 CFR 285.906 - What must my decommissioning application include?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must my decommissioning application include? 285.906 Section 285.906 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF...
Landscape values in public decisions
Richard N. L. Andrews
1979-01-01
The National Environmental Policy Act requires all agencies to develop techniques to insure appropriate consideration of all environmental amenities and values, including those presently unquantified, by all federal agencies in all their activities. These obviously include the values associated with the landscape and its visual resources. The visual resource, however,...
Electronic Resources for Youth Services: A Print Bibliography and Web Site.
ERIC Educational Resources Information Center
Amey, Larry; Segal, Erez
1996-01-01
This article evaluates 57 World Wide Web sites related to children's literature and youth-oriented library services, in categories including award-winning books; book reviews; reading and storytelling; writing resources; online children's literature; educational entertainment; and authors, publishers, and booksellers. Also included is information…
Beyond botany to genetic resource preservation: the S. P. Vander Kloet Vaccinium L. collections
USDA-ARS?s Scientific Manuscript database
Dr. S. P. Vander Kloet, botanist, traveled the world examining and obtaining specimens to redefine infrageneric taxonomic units within Vaccinium L., family Ericaceae. Besides his botanical treatises, his legacy includes herbarium voucher specimens and ex situ genetic resource collections including a...
Vincent, Leslie; Beduz, Mary Agnes
2010-05-01
Evidence of acute nursing shortages in urban hospitals has been surfacing since 2000. Further, new graduate nurses account for more than 50% of total nurse turnover in some hospitals and between 35% and 60% of new graduates change workplace during the first year. Critical to organizational success, first line nurse managers must have the knowledge and skills to ensure the accurate projection of nursing resource requirements and to develop proactive recruitment and retention programs that are effective, promote positive nursing socialization, and provide early exposure to the clinical setting. The Nursing Human Resource Planning Best Practice Toolkit project supported the creation of a network of teaching and community hospitals to develop a best practice toolkit in nursing human resource planning targeted at first line nursing managers. The toolkit includes the development of a framework including the conceptual building blocks of planning tools, manager interventions, retention and recruitment and professional practice models. The development of the toolkit involved conducting a review of the literature for best practices in nursing human resource planning, using a mixed method approach to data collection including a survey and extensive interviews of managers and completing a comprehensive scan of human resource practices in the participating organizations. This paper will provide an overview of the process used to develop the toolkit, a description of the toolkit contents and a reflection on the outcomes of the project.
2004 Pacific Northwest Loads and Resources Study.
DOE Office of Scientific and Technical Information (OSTI.GOV)
United States. Bonneville Power Administration.
2004-12-01
The Pacific Northwest Loads and Resources Study (White Book), which is published annually by the Bonneville Power Administration (BPA), establishes one of the planning bases for supplying electricity to customers. The White Book contains projections of regional and Federal system load and resource capabilities, along with relevant definitions and explanations. The White Book also contains information obtained from formalized resource planning reports and data submittals including those from individual utilities, the Northwest Power and Conservation Council (Council), and the Pacific Northwest Utilities Conference Committee (PNUCC). The White Book is not an operational planning guide, nor is it used for determiningmore » BPA revenues, although the database that generates the data for the White Book analysis contributes to the development of BPA's inventory and ratemaking processes. Operation of the Federal Columbia River Power System (FCRPS) is based on a set of criteria different from that used for resource planning decisions. Operational planning is dependent upon real-time or near-term knowledge of system conditions that include expectations of river flows and runoff, market opportunities, availability of reservoir storage, energy exchanges, and other factors affecting the dynamics of operating a power system. The load resource balance of BPA and/or the region is determined by comparing resource availability to an expected level of total retail electricity consumption. Resources include projected energy capability plus contract purchases. Loads include a forecast of retail obligations plus contract obligations. Surplus energy is available when resources are greater than loads. This energy could be marketed to increase revenues. Energy deficits occur when resources are less than loads. These deficits could be met by any combination of the following: better-than-critical water conditions, demand-side management and conservation programs, permanent loss of loads due to economic conditions or closures, additional contract purchases, and/or the addition of new generating resources. The loads and resources analysis in this study simulates the operation of the power system under the current Pacific Northwest Coordination Agreement (PNCA). The PNCA defines the planning and operation of seventeen U.S. Pacific Northwest utilities and other parties with generating facilities within the region's hydroelectric (hydro) system. The hydroregulation study used for the 2004 White Book incorporates measures from the National Oceanographic and Atmospheric Administration Fisheries (NOAA Fisheries) Biological Opinion dated December 2000, and the U.S. Fish and Wildlife Service's 2000 Biological Opinion (2000 FCRPS BiOps) for the Snake River and Columbia River projects. These measures include: (1) Increased flow augmentation for juvenile fish migrations in the Snake and Columbia rivers in the spring and summer; (2) Mandatory spill requirements at the Lower Snake and Columbia dams to provide for non-turbine passage routes for juvenile fish migrants; and (3) Additional flows for Kootenai River white sturgeon in the spring; The hydroregulation criteria for this analysis includes the following: (1) Detailed Operation Plan operation for Treaty reservoirs for Operating Year (OY) 2004; (2) PNCA planning criteria for OY 2004; and (3) Juvenile fish bypass spill levels for 2000 FCRPS BiOps implementation. The 2004 White Book is presented in two documents: (1) this summary document of Federal system and PNW region loads and resources, and (2) a technical appendix which presents regional loads, grouped by major PNW utility categories, and detailed contract and resource information. The technical appendix is available only in electronic form. Individual customer information for marketer contracts is not detailed due to confidentiality agreements. The 2004 White Book analysis updates the 2003 White Book. This analysis projects the yearly average energy consumption and resource availability for the study period, OY 2006 through 2015. The study shows the Federal system's and the region's expected monthly peak demand, monthly energy demand, monthly peak generating capability, and monthly energy generation for OY 2006, 2010, and 2015. The Federal system and regional monthly capacity surplus/deficit projections are summarized for the 10 operating years of the study period. This document analyzes the PNW's projected loads and available generating resources in two parts: (1) the loads and resources of the Federal system, for which BPA is the marketing agency; and (2) the larger PNW regional power system loads and resources that include the Federal system as well other PNW entities.« less
NASA Astrophysics Data System (ADS)
Ngana, J. O.; Mwalyosi, R. B. B.; Madulu, N. F.; Yanda, P. Z.
Water resources management in Lake Manyara sub-basin is an issue of very high significance as the sub-basin hosts a number of national and global assets of great socio-cultural, ecological and economic values. The sub-basin comprise of a Biosphere Reserve with boosting tourism from Lake Manyara National Park with a variety of wildlife population, large livestock population and highly fertile land for agricultural production. The prevailing system of uncoordinated water resources management in the sub-basin cannot sustain the ever increasing water needs of the various expanding sectors, therefore a strategy must be sought to integrate the various sectoral needs against the available water resources in order to attain both economic and ecological sustainability. Through participatory approach with the stakeholders, the study has established key issues, demonstrated considerable experience in water resources management in the sub-basin including existence of water boards, water committees in some districts as well as land resources management practices However, a number of constraints were noted which inhibit sustainable water resources management including ignorance of water policies, conflicting sectoral policies, lack of coordination between sectors, high in migration rates into the basin, heavy in migration of livestock, conflicts between sectors, poor land use resulting in soil erosion and sedimentation, lack of comprehensive data base on water resources and water needs for : domestic, tourism, livestock, irrigation, wild life and environmental flows. As a way forward it was recommended that a basin wide legally mandated body (involving all levels) be established to oversee water use in the sub-basin. Other strategies include capacity building of stakeholders on water natural resources management policies, water rights and enforcement of laws. This progress report paper highlights the wealth of knowledge that stakeholders possess on water resources management and using that platform develop a participatory Integrated water resources management where roles and responsibilities are ironed out.
Application of random effects to the study of resource selection by animals
Gillies, C.S.; Hebblewhite, M.; Nielsen, S.E.; Krawchuk, M.A.; Aldridge, Cameron L.; Frair, J.L.; Saher, D.J.; Stevens, C.E.; Jerde, C.L.
2006-01-01
1. Resource selection estimated by logistic regression is used increasingly in studies to identify critical resources for animal populations and to predict species occurrence.2. Most frequently, individual animals are monitored and pooled to estimate population-level effects without regard to group or individual-level variation. Pooling assumes that both observations and their errors are independent, and resource selection is constant given individual variation in resource availability.3. Although researchers have identified ways to minimize autocorrelation, variation between individuals caused by differences in selection or available resources, including functional responses in resource selection, have not been well addressed.4. Here we review random-effects models and their application to resource selection modelling to overcome these common limitations. We present a simple case study of an analysis of resource selection by grizzly bears in the foothills of the Canadian Rocky Mountains with and without random effects.5. Both categorical and continuous variables in the grizzly bear model differed in interpretation, both in statistical significance and coefficient sign, depending on how a random effect was included. We used a simulation approach to clarify the application of random effects under three common situations for telemetry studies: (a) discrepancies in sample sizes among individuals; (b) differences among individuals in selection where availability is constant; and (c) differences in availability with and without a functional response in resource selection.6. We found that random intercepts accounted for unbalanced sample designs, and models with random intercepts and coefficients improved model fit given the variation in selection among individuals and functional responses in selection. Our empirical example and simulations demonstrate how including random effects in resource selection models can aid interpretation and address difficult assumptions limiting their generality. This approach will allow researchers to appropriately estimate marginal (population) and conditional (individual) responses, and account for complex grouping, unbalanced sample designs and autocorrelation.
Application of random effects to the study of resource selection by animals.
Gillies, Cameron S; Hebblewhite, Mark; Nielsen, Scott E; Krawchuk, Meg A; Aldridge, Cameron L; Frair, Jacqueline L; Saher, D Joanne; Stevens, Cameron E; Jerde, Christopher L
2006-07-01
1. Resource selection estimated by logistic regression is used increasingly in studies to identify critical resources for animal populations and to predict species occurrence. 2. Most frequently, individual animals are monitored and pooled to estimate population-level effects without regard to group or individual-level variation. Pooling assumes that both observations and their errors are independent, and resource selection is constant given individual variation in resource availability. 3. Although researchers have identified ways to minimize autocorrelation, variation between individuals caused by differences in selection or available resources, including functional responses in resource selection, have not been well addressed. 4. Here we review random-effects models and their application to resource selection modelling to overcome these common limitations. We present a simple case study of an analysis of resource selection by grizzly bears in the foothills of the Canadian Rocky Mountains with and without random effects. 5. Both categorical and continuous variables in the grizzly bear model differed in interpretation, both in statistical significance and coefficient sign, depending on how a random effect was included. We used a simulation approach to clarify the application of random effects under three common situations for telemetry studies: (a) discrepancies in sample sizes among individuals; (b) differences among individuals in selection where availability is constant; and (c) differences in availability with and without a functional response in resource selection. 6. We found that random intercepts accounted for unbalanced sample designs, and models with random intercepts and coefficients improved model fit given the variation in selection among individuals and functional responses in selection. Our empirical example and simulations demonstrate how including random effects in resource selection models can aid interpretation and address difficult assumptions limiting their generality. This approach will allow researchers to appropriately estimate marginal (population) and conditional (individual) responses, and account for complex grouping, unbalanced sample designs and autocorrelation.
NASA SMD and DPS Resources for Higher Education Faculty
NASA Astrophysics Data System (ADS)
Buxner, Sanlyn; Grier, Jennifer; Meinke, Bonnie; Schneider, Nick; Low, Rusty; Schultz, Greg; Manning, James; Fraknoi, Andrew; Gross, Nicholas
2015-11-01
The NASA Education and Public Outreach Forums have developed and provided resources for higher education for the past six years through a cooperative agreement with NASA’s Science Mission Directorate. Collaborations with science organizations, including AAS’s Division of Planetary Sciences, have resulted in more tools, professional training opportunities, and dissemination of resources for teaching in the undergraduate classroom. Resources have been developed through needs assessments of the community and with input from scientists and undergraduate instructors. All resources are freely available.NASA Wavelength (nasawavelength.org) is a collection of digital peer reviewed Earth and space science resources for formal and informal educators of all levels. All resources were developed through funding of the NASA Science Mission Directorate and have undergone a peer-review process through which educators and scientists ensure the content is accurate and useful in an educational setting. Within NASA Wavelength are specific lists of activities and resources for higher education faculty. Additionally, several resources have been developed for introductory college classrooms. The DPS Discovery slide sets are 3-slide presentations that can be incorporated into college lectures to keep classes apprised of the fast moving field of planetary science (http://dps.aas.org/education/dpsdisc). The “Astro 101 slide sets”, developed by the Astro Forum, are presentations 5-7 slides in length on a new development or discovery from a NASA Astrophysics mission relevant to topics in introductory astronomy courses of discoveries not yet in textbooks. Additional resources guides are available for Astro 101 courses and include cosmology and exoplanets. (https://www.astrosociety.org/education/resources-for-the-higher-education-audience/).Professional development opportunities are available to faculty to increase content knowledge and pedagogical tools. These include workshops at scientific meetings and online webinars that are archived for later viewing. For more information, visit the SMD E/PO community workspace at http://smdepo.org.
Facilitating access to pre-processed research evidence in public health
2010-01-01
Background Evidence-informed decision making is accepted in Canada and worldwide as necessary for the provision of effective health services. This process involves: 1) clearly articulating a practice-based issue; 2) searching for and accessing relevant evidence; 3) appraising methodological rigor and choosing the most synthesized evidence of the highest quality and relevance to the practice issue and setting that is available; and 4) extracting, interpreting, and translating knowledge, in light of the local context and resources, into practice, program and policy decisions. While the public health sector in Canada is working toward evidence-informed decision making, considerable barriers, including efficient access to synthesized resources, exist. Methods In this paper we map to a previously developed 6 level pyramid of pre-processed research evidence, relevant resources that include public health-related effectiveness evidence. The resources were identified through extensive searches of both the published and unpublished domains. Results Many resources with public health-related evidence were identified. While there were very few resources dedicated solely to public health evidence, many clinically focused resources include public health-related evidence, making tools such as the pyramid, that identify these resources, particularly helpful for public health decisions makers. A practical example illustrates the application of this model and highlights its potential to reduce the time and effort that would be required by public health decision makers to address their practice-based issues. Conclusions This paper describes an existing hierarchy of pre-processed evidence and its adaptation to the public health setting. A number of resources with public health-relevant content that are either freely accessible or requiring a subscription are identified. This will facilitate easier and faster access to pre-processed, public health-relevant evidence, with the intent of promoting evidence-informed decision making. Access to such resources addresses several barriers identified by public health decision makers to evidence-informed decision making, most importantly time, as well as lack of knowledge of resources that house public health-relevant evidence. PMID:20181270
Hoffman, Robert; Woodward, Andrea; Haggerty, Patricia K.; Jenkins, Kurt J.; Griffin, Paul C.; Adams, Michael J.; Hagar, Joan; Cummings, Tonnie; Duriscoe, Dan; Kopper, Karen; Riedel, Jon; Samora, Barbara; Marin, Lelaina; Mauger, Guillaume S.; Bumbaco, Karen; Littell, Jeremy S.
2014-01-01
Natural Resource Condition Assessments (NRCAs) evaluate current conditions for a subset of natural resources and resource indicators in national parks. NRCAs also report on trends in resource condition (when possible), identify critical data gaps, and characterize a general level of confidence for study findings. The resources and indicators emphasized in a given project depend on the park’s resource setting, status of resource stewardship planning and science in identifying high-priority indicators, and availability of data and expertise to assess current conditions for a variety of potential study resources and indicators. Although the primary objective of NRCAs is to report on current conditions relative to logical forms of reference conditions and values, NRCAs also report on trends, when appropriate (i.e., when the underlying data and methods support such reporting), as well as influences on resource conditions. These influences may include past activities or conditions that provide a helpful context for understanding current conditions and present-day threats and stressors that are best interpreted at park, watershed, or landscape scales (though NRCAs do not report on condition status for land areas and natural resources beyond park boundaries). Intensive cause-andeffect analyses of threats and stressors, and development of detailed treatment options, are outside the scope of NRCAs. It is also important to note that NRCAs do not address resources that lack sufficient data for assessment. For Mount Rainier National Park, this includes most invertebrate species and many other animal species that are subject to significant stressors from climate change and other anthropogenic sources such as air pollutants and recreational use. In addition, we did not include an analysis of the physical hydrology associated with streams (such as riverine landforms, erosion and aggradation which is significant in MORA streams), due to a loss of staff expertise from the USGS-BRD staff conducting the work, and human disturbance landcover issues such as the effects of roads, trails, and other anthropogenic developments due to lack of funds.
Inclusive Schools. Topical Bibliography on Inclusive Schools.
ERIC Educational Resources Information Center
Sorenson, Barbara, Comp.; Drill, Janet, Comp.
This abstract bibliography of approximately 200 references looks at various aspects of inclusive schools. References are a result of computer searches of three databases: the Educational Resources Information Center (ERIC), Exceptional Child Education Resources, and the Western Regional Resources Center. Preliminary information includes directions…
Implementing CORAL: An Electronic Resource Management System
ERIC Educational Resources Information Center
Whitfield, Sharon
2011-01-01
A 2010 electronic resource management survey conducted by Maria Collins of North Carolina State University and Jill E. Grogg of University of Alabama Libraries found that the top six electronic resources management priorities included workflow management, communications management, license management, statistics management, administrative…
77 FR 25060 - Flower Garden Banks National Marine Sanctuary Regulations
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-27
... monitoring, resource protection, visitor use, and operations and administration. Because the resource protection and visitor use action plans include several strategies that require changes to the FGBNMS... sanctuary resources from user impacts, clarify discharge language, and make other technical changes and...
ERIC Educational Resources Information Center
Scharf, Davida
2002-01-01
Discussion of improving accessibility to copyrighted electronic content focuses on the Digital Object Identifier (DOI) and the Open URL standard and linking software. Highlights include work of the World Wide Web consortium; URI (Uniform Resource Identifier); URL (Uniform Resource Locator); URN (Uniform Resource Name); OCLC's (Online Computer…
Current Issues for Higher Education Information Resources Management.
ERIC Educational Resources Information Center
CAUSE/EFFECT, 1996
1996-01-01
Issues identified as important to the future of information resources management and use in higher education include information policy in a networked environment, distributed computing, integrating information resources and college planning, benchmarking information technology, integrated digital libraries, technology integration in teaching,…
EVALUATING THE CONDITION OF RIVERINE-RIPARIAN RESOURCES IN THE PACIFIC NORTHWEST
The evaluation of the condition of riverine-riparian resources at regional scales relies on the interpretation of measurements taken on a variety of attributes reflecting both status and processes governing status of these resources. Typical attributes include indicators of upsl...
25 CFR 163.70 - Purpose of agreements.
Code of Federal Regulations, 2012 CFR
2012-04-01
... programs; (2) Develop and publish cooperative environmental education and natural resource planning materials; and (3) Perform land and facility improvements, including forestry and other natural resources... related to land and natural resource management. (b) The Secretary may enter into such agreements when he...
25 CFR 163.70 - Purpose of agreements.
Code of Federal Regulations, 2013 CFR
2013-04-01
... programs; (2) Develop and publish cooperative environmental education and natural resource planning materials; and (3) Perform land and facility improvements, including forestry and other natural resources... related to land and natural resource management. (b) The Secretary may enter into such agreements when he...
25 CFR 163.70 - Purpose of agreements.
Code of Federal Regulations, 2014 CFR
2014-04-01
... programs; (2) Develop and publish cooperative environmental education and natural resource planning materials; and (3) Perform land and facility improvements, including forestry and other natural resources... related to land and natural resource management. (b) The Secretary may enter into such agreements when he...
25 CFR 163.70 - Purpose of agreements.
Code of Federal Regulations, 2010 CFR
2010-04-01
... programs; (2) Develop and publish cooperative environmental education and natural resource planning materials; and (3) Perform land and facility improvements, including forestry and other natural resources... related to land and natural resource management. (b) The Secretary may enter into such agreements when he...
25 CFR 163.70 - Purpose of agreements.
Code of Federal Regulations, 2011 CFR
2011-04-01
... programs; (2) Develop and publish cooperative environmental education and natural resource planning materials; and (3) Perform land and facility improvements, including forestry and other natural resources... related to land and natural resource management. (b) The Secretary may enter into such agreements when he...
Solid Waste: Resource Recovery and Reuse
ERIC Educational Resources Information Center
Bernardo, James V.
1973-01-01
Discusses some of the processes involved in resource recovery (recycling) from municipal solid wastes. Provides specific examples of recovery of valuable resources, and suggests that the environmental consequences and technology related to solid waste treatment should be included in high school science courses. (JR)
Assistive Technology Resource Directory.
ERIC Educational Resources Information Center
Council for Exceptional Children, Reston, VA. Center for Special Education Technology.
This annotated directory of resources is designed to assist in locating key organizations, agencies, and projects that are involved in the delivery of assistive technology services at the national, state, and local levels. Resources described include three federal agencies, nine national associations, five rehabilitation engineering centers, four…
Improving Writing: Resources, Strategies, Assessments.
ERIC Educational Resources Information Center
Lenski, Susan Davis; Johns, Jerry L.
Comprehensive and practical, this book provides resources, strategies, and assessments that seamlessly weave writing into everyday classroom routines. The resources in the book include reproducible student worksheets, transparency masters, teacher and student examples, and technology tips in the form of Web site addresses. Strategies throughout…
30 CFR 585.659 - What requirements must I include in my SAP, COP, or GAP regarding air quality?
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 2 2013-07-01 2013-07-01 false What requirements must I include in my SAP, COP, or GAP regarding air quality? 585.659 Section 585.659 Mineral Resources BUREAU OF OCEAN ENERGY... What requirements must I include in my SAP, COP, or GAP regarding air quality? (a) You must comply with...
30 CFR 585.659 - What requirements must I include in my SAP, COP, or GAP regarding air quality?
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 2 2014-07-01 2014-07-01 false What requirements must I include in my SAP, COP, or GAP regarding air quality? 585.659 Section 585.659 Mineral Resources BUREAU OF OCEAN ENERGY... What requirements must I include in my SAP, COP, or GAP regarding air quality? (a) You must comply with...
30 CFR 585.659 - What requirements must I include in my SAP, COP, or GAP regarding air quality?
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What requirements must I include in my SAP, COP, or GAP regarding air quality? 585.659 Section 585.659 Mineral Resources BUREAU OF OCEAN ENERGY... What requirements must I include in my SAP, COP, or GAP regarding air quality? (a) You must comply with...
Code of Federal Regulations, 2011 CFR
2011-04-01
... DEVELOPMENT AND SELF DETERMINATION ACT Procedures for Obtaining Tribal Energy Resource Agreements Tera Requirements § 224.64 How may a tribe assume management of development of different types of energy resources... for development of another energy resource that is not included in the TERA, a tribe must apply for a...
Riegel, Lisa Diaz; Wakild, Charles; Boothe, Laura; Hildebrandt, Heather J; Nicholson, Bruce
2012-01-01
The North Carolina Department of Environment and Natural Resources works with communities and other agencies to sustain clean air, water, and land. Sustainability efforts include protecting air quality through community design, community enhancement through brownfields revitalization, community development strategies to protect water resources, and the integration of natural resource conservation.
Environmental Assessment for Airborne Laser Debris Management Vandenberg AFB, California
2008-07-01
use, aesthetics, hazardous materials management, soils and geology, noise, cultural resources, and environmental justice. The resources analyzed in...more detail include: health and safety, hazardous waste management, water resources, air quality, and biological resources. Environmental Effects Under...either intact or destroyed target missiles could result in several potential hazards . Health and Safety. Based on the debris migration modeling and
Space Science Education Resource Directory
NASA Astrophysics Data System (ADS)
Christian, C. A.; Scollick, K.
The Office of Space Science (OSS) of NASA supports educational programs as a by-product of the research it funds through missions and investigative programs. A rich suite of resources for public use is available including multimedia materials, online resources, hardcopies and other items. The OSS supported creation of a resource catalog through a group lead by individuals at STScI that ultimately will provide an easy-to-use and user-friendly search capability to access products. This paper describes the underlying architecture of that catalog, including the challenge to develop a system for characterizing education products through appropriate metadata. The system must also be meaningful to a large clientele including educators, scientists, students, and informal science educators. An additional goal was to seamlessly exchange data with existing federally supported educational systems as well as local systems. The goals, requirements, and standards for the catalog will be presented to illuminate the rationale for the implementation ultimately adopted.
Preliminary Model of Porphyry Copper Deposits
Berger, Byron R.; Ayuso, Robert A.; Wynn, Jeffrey C.; Seal, Robert R.
2008-01-01
The U.S. Geological Survey (USGS) Mineral Resources Program develops mineral-deposit models for application in USGS mineral-resource assessments and other mineral resource-related activities within the USGS as well as for nongovernmental applications. Periodic updates of models are published in order to incorporate new concepts and findings on the occurrence, nature, and origin of specific mineral deposit types. This update is a preliminary model of porphyry copper deposits that begins an update process of porphyry copper models published in USGS Bulletin 1693 in 1986. This update includes a greater variety of deposit attributes than were included in the 1986 model as well as more information about each attribute. It also includes an expanded discussion of geophysical and remote sensing attributes and tools useful in resource evaluations, a summary of current theoretical concepts of porphyry copper deposit genesis, and a summary of the environmental attributes of unmined and mined deposits.
Atmospheric Sciences Information Resources in the United States--An Overview for Librarians.
ERIC Educational Resources Information Center
Layman, Mary; Smith, Shirley
1993-01-01
Presents an overview of the types of information and information sources available in the field of atmospheric sciences. Included are major library collections; organizations; government programs, including air pollution control regulations; electronic databases; and networking resources. Addresses are provided for all sources, and definitions of…
18 CFR 1312.6 - Application for permits and information collection.
Code of Federal Regulations, 2013 CFR
2013-04-01
... include: (1) The nature and extent of the work proposed, including how and why it is proposed to be... resources on public lands, the names of the university, museum, or other scientific or educational... removal of archaeological resources on Indian lands, the name of the university, museum, or other...
18 CFR 1312.6 - Application for permits and information collection.
Code of Federal Regulations, 2012 CFR
2012-04-01
... include: (1) The nature and extent of the work proposed, including how and why it is proposed to be... resources on public lands, the names of the university, museum, or other scientific or educational... removal of archaeological resources on Indian lands, the name of the university, museum, or other...
18 CFR 1312.6 - Application for permits and information collection.
Code of Federal Regulations, 2011 CFR
2011-04-01
... include: (1) The nature and extent of the work proposed, including how and why it is proposed to be... resources on public lands, the names of the university, museum, or other scientific or educational... removal of archaeological resources on Indian lands, the name of the university, museum, or other...
18 CFR 367.3960 - Account 396, Power operated equipment.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Account 396, Power operated equipment. 367.3960 Section 367.3960 Conservation of Power and Water Resources FEDERAL ENERGY... work exclusive of equipment includible in other accounts. Include, also, the tools and accessories...
18 CFR 367.3960 - Account 396, Power operated equipment.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Account 396, Power operated equipment. 367.3960 Section 367.3960 Conservation of Power and Water Resources FEDERAL ENERGY... work exclusive of equipment includible in other accounts. Include, also, the tools and accessories...
18 CFR 367.3960 - Account 396, Power operated equipment.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Account 396, Power operated equipment. 367.3960 Section 367.3960 Conservation of Power and Water Resources FEDERAL ENERGY... work exclusive of equipment includible in other accounts. Include, also, the tools and accessories...
18 CFR 367.3960 - Account 396, Power operated equipment.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Account 396, Power operated equipment. 367.3960 Section 367.3960 Conservation of Power and Water Resources FEDERAL ENERGY... work exclusive of equipment includible in other accounts. Include, also, the tools and accessories...
30 CFR 285.908 - What must I include in my decommissioning notice?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my decommissioning notice? 285.908 Section 285.908 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF...
76 FR 35187 - Fremont and Winema Resource Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-16
... Committee will meet in Lakeview Oregon, for the purpose of evaluating and recommending resource management projects for funding in FY 2012, under the provisions of Title II of the Secure Rural Schools and Community... including presentations by project proponents. Business items will include the prioritization and ranking of...
77 FR 47814 - Fremont and Winema Resource Advisory Committee
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-10
... management projects for funding in FY 2013, under the provisions of Title II of the Secure Rural Schools and... will include a review, and evaluation, of FY 2013 Title II proposals including presentations by project... final recommendations for funding of fiscal year 2013 projects. All Fremont and Winema Resource Advisory...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-28
...); Water resources, fisheries, and wetlands; Cultural resources; Vegetation and wildlife, including... groups; Native American Tribes; other interested parties; and local libraries and newspapers. This list... filing a request to intervene. Instructions for becoming an intervenor are included in the User's Guide...
Guaranteed Access to Campus Network Resources: Policies and Issues.
ERIC Educational Resources Information Center
Hassler, Ardoth A.
1998-01-01
Reports on a options and issues discussion at a December 1997 Orlando (Florida) meeting of CAUSE97 on providing access to campus technology resources. Options discussed included departmentally and/or university-owned modems, third-party provider contracts, and using wireless access. Issues included providing authentication, assuring network…
30 CFR 250.241 - What must the DPP or DOCD include?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What must the DPP or DOCD include? 250.241 Section 250.241 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT... and Information Contents of Development and Production Plans (dpp) and Development Operations...
Professional Development Guide for Educators. The Multicultural Resource Series, Volume 1.
ERIC Educational Resources Information Center
Gorski, Paul, Ed.; Shin, Gene-Tey, Ed.; Green, Martha, Ed.
This guide presents a collection of personal essays written by educators who describe how multicultural education has transformed their teaching. It also includes resources such as multicultural organizations, publications, videos, and Web sites. Chapter 1, "Multicultural Education: Voices and Visions," includes "Ethiopia at the Bar…
30 CFR 285.908 - What must I include in my decommissioning notice?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What must I include in my decommissioning notice? 285.908 Section 285.908 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND... the impacts previously identified and evaluated; (2) Require any additional Federal permits; or (3...
ERIC Educational Resources Information Center
Lee, Tom E.; And Others
This compilation of resource units concerns the latest developments in space biology. Some of the topics included are oxygen consumption, temperature, radiation, rhythms, weightlessness, acceleration and vibration stress, toxicity, and sensory and perceptual problems. Many of the topics are interdisciplinary and relate biology, physiology,…
ERIC Educational Resources Information Center
Federal Aviation Administration (DOT), Washington, DC. Office of Public Affairs.
Currently available aviation education resource materials are listed alphabetically by title under four headings: (1) career information; (2) audiovisual materials; (3) publications; and (4) periodicals. Each entry includes: title; format (16mm film, slides, slide/tape presentation, VHS/Beta videotape, book, booklet, newsletter, pamphlet, poster,…
,
1981-01-01
Research in the WRD had its beginnings in the late 1950's when the "core research" line item was added to the Congressional budget. Since this time the Federal program has grown from a "basic sciences" program to one that includes a broad spectrum of basic and applied scientific investigations. Water resources research in WRD includes the study of water in all its phases and uses the basic sciences of mathematics, chemistry, physics, biology, geology and engineering to gain a fundamental understanding of the processes that affect the movement of water and its chemical constituents through hydrologic systems. The basic knowledge and methodologies derived from water resources research are applicable not only to the solution of current problems associated with the Nation's water resources, but also to anticipated hydrologic issues.
Geothermal direct heat use: Market potential/penetration analysis for Federal Region 9
NASA Technical Reports Server (NTRS)
Powell, W. (Editor); Tang, K. (Editor)
1980-01-01
A preliminary study was made of the potential for geothermal direct heat use in Arizona, California, Hawaii, and Nevada (Federal Region 9). An analysis was made of each state to: (1) define the resource, based on the latest available data; (2) assess the potential market growth for geothermal energy; and (3) estimate the market penetration, projected to 2020. Findings of the study include the following: (1) Potentially economical hydrothermal resources exist in all four states of the Region: however, the resource data base is largely incomplete, particularly for low to moderate temperature resources. (2) In terms of beneficial heat, the total hydrothermal resource identified so far for the four states is on the order of 43 Quads, including an estimated 34 Quads of high temperature resources which are suitable for direct as well as electrical applications. (3) In California, Hawaii, and Nevada, the industrial market sector has somewhat greater potential for penetration than the residential/commercial sector. In Arizona, however, the situation is reversed, due to the collocation of two major metropolitan areas (Phoenix and Tucson) with potential geothermal resources.
Water resources activities in Kentucky, 1993-94
Maglothin, L. S.; Forbes, R.W.
1994-01-01
The U.S. Geological Survey (USGS) is the principal Federal water-resources data collection and investigation agency. Through the Water Resources Division District Office in Kentucky, the USGS investigates the occurrence, distribution, quantity, movement, and chemical and biological quality of surface and ground water in the State. The mission of this program is to collect, interpret, and publish information on water resources. Almost all research and data collection is a cooperative effort in which planning and financial support are shared by State and local agencies and governments. Other activities are funded by other Federal agencies or by direct Congressional appropriation. This report is intended to inform the public and cooperating agencies, vitally interested in the water resources of Kentucky, as to the current status of the Distfict's data collection and investigation program. Included in the report are summaries of water-resources activities in Kentucky conducted by the USGS. Also included is a description of the USGS mission and program, District organization, funding sources and cooperating agencies, and a list of USGS publications relevant to the water resources of the State.
NASA Astrophysics Data System (ADS)
Kellagher, E.; Buhr, S. M.; Lynds, S. E.; McCaffrey, M. S.; Cires Education Outreach
2011-12-01
Inspiring Climate Education Excellence (ICEE) is a NASA-funded project to develop content knowledge and knowledge of effective teaching strategies in climate education among secondary science teachers. ICEE resources are aligned with the Essential Principles of Climate Science. Building upon a needs assessment and face to face workshop, ICEE resources include iTunesU videos, an ICEE 101 resource site with videos and peer-reviewed learning activities, and a moderated online forum. Self-directed modules and an online course are being developed around concepts and topics in which teachers express the most interest and need for instruction. ICEE resources include attention to effective teaching strategies, such as awareness of student misconceptions, strategies for forestalling controversy and advice from master teachers on implementation and curriculum development. The resources are being developed in partnership with GLOBE, and the National Science Digital Library (NSDL) and are informed by the work of the Climate Literacy and Energy Awareness Network (CLEAN) project. ICEE will help to meet the professional development needs of teachers, including those participating in the GLOBE Student Climate Research Campaign.
Hall, William; Smith, Neale; Mitton, Craig; Urquhart, Bonnie; Bryan, Stirling
2017-08-22
In order to meet the challenges presented by increasing demand and scarcity of resources, healthcare organizations are faced with difficult decisions related to resource allocation. Tools to facilitate evaluation and improvement of these processes could enable greater transparency and more optimal distribution of resources. The Resource Allocation Performance Assessment Tool (RAPAT) was implemented in a healthcare organization in British Columbia, Canada. Recommendations for improvement were delivered, and a follow up evaluation exercise was conducted to assess the trajectory of the organization's priority setting and resource allocation (PSRA) process 2 years post the original evaluation. Implementation of RAPAT in the pilot organization identified strengths and weaknesses of the organization's PSRA process at the time of the original evaluation. Strengths included the use of criteria and evidence, an ability to reallocate resources, and the involvement of frontline staff in the process. Weaknesses included training, communication, and lack of program budgeting. Although the follow up revealed a regression from a more formal PSRA process, a legacy of explicit resource allocation was reported to be providing ongoing benefit for the organization. While past studies have taken a cross-sectional approach, this paper introduces the first longitudinal evaluation of PSRA in a healthcare organization. By including the strengths, weaknesses, and evolution of one organization's journey, the authors' intend that this paper will assist other healthcare leaders in meeting the challenges of allocating scarce resources. © 2018 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Byrnett, D. S.; Mulholland, D.; Zinsmeister, E.
One renewable energy option that states frequently consider to meet their clean energy goals is the use of biomass resources to develop bioenergy. Bioenergy includes bioheat, biopower, biofuels, and bioproducts. This document provides an overview of biomass feedstocks, basic information about biomass conversion technologies, and a discussion of benefits and challenges of bioenergy options. The Primer includes a step-wise framework, resources, and tools for determining the availability of feedstocks, assessing potential markets for biomass, and identifying opportunities for action at the state level. Each chapter contains a list of selected resources and tools that states can use to explore topicsmore » in further detail.« less
2006 Pacific Northwest Loads and Resources Study.
DOE Office of Scientific and Technical Information (OSTI.GOV)
United States. Bonneville Power Administration.
2006-03-01
The Pacific Northwest Loads and Resources Study (White Book), which is published annually by the Bonneville Power Administration (BPA), establishes one of the planning bases for supplying electricity to customers. The White Book contains projections of regional and Federal system load and resource capabilities, along with relevant definitions and explanations. The White Book also contains information obtained from formalized resource planning reports and data submittals including those from individual utilities, the Northwest Power and Conservation Council (Council), and the Pacific Northwest Utilities Conference Committee (PNUCC). The White Book is not an operational planning guide, nor is it used for determiningmore » BPA revenues, although the database that generates the data for the White Book analysis contributes to the development of BPA's inventory and ratemaking processes. Operation of the Federal Columbia River Power System (FCRPS) is based on a set of criteria different from that used for resource planning decisions. Operational planning is dependent upon real-time or near-term knowledge of system conditions that include expectations of river flows and runoff, market opportunities, availability of reservoir storage, energy exchanges, and other factors affecting the dynamics of operating a power system. The load resource balance of both the Federal system and the region is determined by comparing resource availability to an expected level of total retail electricity consumption. Resources include projected energy capability plus contract purchases. Loads include a forecast of retail obligations plus contract obligations. Surplus energy is available when resources are greater than loads. This surplus energy could be marketed to increase revenues. Energy deficits occur when resources are less than loads. These energy deficits will be met by any combination of the following: better-than-critical water conditions, demand-side management and conservation programs, permanent loss of loads due to economic conditions or closures, additional contract purchases, and/or the addition of new generating resources. This study incorporates information on Pacific Northwest (PNW) regional retail loads, contract obligations, and contract resources. This loads and resources analysis simulates the operation of the power system in the PNW. The simulated hydro operation incorporates plant characteristics, streamflows, and non-power requirements from the current Pacific Northwest Coordination Agreement (PNCA). Additional resource capability estimates were provided by BPA, PNW Federal agency, public agency, cooperative, U.S. Bureau of Reclamation (USBR), and investor-owned utility (IOU) customers furnished through annual PNUCC data submittals for 2005 and/or direct submittals to BPA. The 2006 White Book is presented in two documents: (1) this summary document of Federal system and PNW region loads and resources, and (2) a technical appendix which presents regional loads, grouped by major PNW utility categories, and detailed contract and resource information. The technical appendix is available only in electronic form. Individual customer information for marketer contracts is not detailed due to confidentiality agreements. The 2006 White Book analysis updates the 2004 White Book. This analysis shows projections of the Federal system and region's yearly average annual energy consumption and resource availability for the study period, OY 2007-2016. The study also presents projections of Federal system and region expected 1-hour monthly peak demand, monthly energy demand, monthly 1-hour peak generating capability, and monthly energy generation for OY 2007, 2011, and 2016. BPA is investigating a new approach in capacity planning depicting the monthly Federal system 120-hour peak generating capability and 120-hour peak surplus/deficit for OY 2007, 2011, and 2016. This document analyzes the PNW's projected loads and available generating resources in two parts: (1) the loads and resources of the Federal system, for which BPA is the marketing agency; and (2) the larger PNW regional power system loads and resources that include the Federal system as well other PNW entities.« less
Diversity in computing technologies and strategies for dynamic resource allocation
Garzoglio, G.; Gutsche, O.
2015-12-23
Here, High Energy Physics (HEP) is a very data intensive and trivially parallelizable science discipline. HEP is probing nature at increasingly finer details requiring ever increasing computational resources to process and analyze experimental data. In this paper, we discuss how HEP provisioned resources so far using Grid technologies, how HEP is starting to include new resource providers like commercial Clouds and HPC installations, and how HEP is transparently provisioning resources at these diverse providers.
The Health Impact Assessment (HIA) Resource and Tool ...
Health Impact Assessment (HIA) is a relatively new and rapidly emerging field in the U.S. An inventory of available HIA resources and tools was conducted, with a primary focus on resources developed in the U.S. The resources and tools available to HIA practitioners in the conduct of their work were identified through multiple methods and compiled into a comprehensive list. The compilation includes tools and resources related to the HIA process itself and those that can be used to collect and analyze data, establish a baseline profile, assess potential health impacts, and establish benchmarks and indicators for monitoring and evaluation. These resources include literature and evidence bases, data and statistics, guidelines, benchmarks, decision and economic analysis tools, scientific models, methods, frameworks, indices, mapping, and various data collection tools. Understanding the data, tools, models, methods, and other resources available to perform HIAs will help to advance the HIA community of practice in the U.S., improve the quality and rigor of assessments upon which stakeholder and policy decisions are based, and potentially improve the overall effectiveness of HIA to promote healthy and sustainable communities. The Health Impact Assessment (HIA) Resource and Tool Compilation is a comprehensive list of resources and tools that can be utilized by HIA practitioners with all levels of HIA experience to guide them throughout the HIA process. The HIA Resource
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1994-02-01
The Salt Lake City Area Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Green, Gunnison, Rio Grande, and Colorado rivers and on Deer and Plateau creeks in the states of Wyoming, Utah, Colorado, Arizona, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams;) are influenced bymore » Western power scheduling and transmission decisions. The EIS alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Westerns firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this environmental impact statement (EIS) include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources.« less
FermiGrid—experience and future plans
NASA Astrophysics Data System (ADS)
Chadwick, K.; Berman, E.; Canal, P.; Hesselroth, T.; Garzoglio, G.; Levshina, T.; Sergeev, V.; Sfiligoi, I.; Sharma, N.; Timm, S.; Yocum, D. R.
2008-07-01
Fermilab supports a scientific program that includes experiments and scientists located across the globe. In order to better serve this community, Fermilab has placed its production computer resources in a Campus Grid infrastructure called 'FermiGrid'. The FermiGrid infrastructure allows the large experiments at Fermilab to have priority access to their own resources, enables sharing of these resources in an opportunistic fashion, and movement of work (jobs, data) between the Campus Grid and National Grids such as Open Science Grid (OSG) and the Worldwide LHC Computing Grid Collaboration (WLCG). FermiGrid resources support multiple Virtual Organizations (VOs), including VOs from the OSG, EGEE, and the WLCG. Fermilab also makes leading contributions to the Open Science Grid in the areas of accounting, batch computing, grid security, job management, resource selection, site infrastructure, storage management, and VO services. Through the FermiGrid interfaces, authenticated and authorized VOs and individuals may access our core grid services, the 10,000+ Fermilab resident CPUs, near-petabyte (including CMS) online disk pools and the multi-petabyte Fermilab Mass Storage System. These core grid services include a site wide Globus gatekeeper, VO management services for several VOs, Fermilab site authorization services, grid user mapping services, as well as job accounting and monitoring, resource selection and data movement services. Access to these services is via standard and well-supported grid interfaces. We will report on the user experience of using the FermiGrid campus infrastructure interfaced to a national cyberinfrastructure - the successes and the problems.
COMPUTATIONAL RESOURCES FOR BIOFUEL FEEDSTOCK SPECIES
DOE Office of Scientific and Technical Information (OSTI.GOV)
Buell, Carol Robin; Childs, Kevin L
2013-05-07
While current production of ethanol as a biofuel relies on starch and sugar inputs, it is anticipated that sustainable production of ethanol for biofuel use will utilize lignocellulosic feedstocks. Candidate plant species to be used for lignocellulosic ethanol production include a large number of species within the Grass, Pine and Birch plant families. For these biofuel feedstock species, there are variable amounts of genome sequence resources available, ranging from complete genome sequences (e.g. sorghum, poplar) to transcriptome data sets (e.g. switchgrass, pine). These data sets are not only dispersed in location but also disparate in content. It will be essentialmore » to leverage and improve these genomic data sets for the improvement of biofuel feedstock production. The objectives of this project were to provide computational tools and resources for data-mining genome sequence/annotation and large-scale functional genomic datasets available for biofuel feedstock species. We have created a Bioenergy Feedstock Genomics Resource that provides a web-based portal or clearing house for genomic data for plant species relevant to biofuel feedstock production. Sequence data from a total of 54 plant species are included in the Bioenergy Feedstock Genomics Resource including model plant species that permit leveraging of knowledge across taxa to biofuel feedstock species.We have generated additional computational analyses of these data, including uniform annotation, to facilitate genomic approaches to improved biofuel feedstock production. These data have been centralized in the publicly available Bioenergy Feedstock Genomics Resource (http://bfgr.plantbiology.msu.edu/).« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
The Salt Lake City Area Office of the Western Area Power Administration (Western) markets electricity produced at hydroelectric facilities operated by the Bureau of Reclamation. The facilities are known collectively as the Salt Lake City Area Integrated Projects (SLCA/IP) and include dams equipped for power generation on the Green, Gunnison, Rio Grande, and Colorado rivers and on Deer and Plateau creeks in the states of Wyoming, Utah, Colorado, Arizona, and New Mexico. Of these facilities, only the Glen Canyon Unit, the Flaming Gorge Unit, and the Aspinall Unit (which includes Blue Mesa, Morrow Point, and Crystal dams;) are influenced bymore » Western power scheduling and transmission decisions. The EIS alternatives, called commitment-level alternatives, reflect combinations of capacity and energy that would feasibly and reasonably fulfill Westerns firm power marketing responsibilities, needs, and statutory obligations. The viability of these alternatives relates directly to the combination of generation capability of the SLCA/IP with energy purchases and interchange. The economic and natural resource assessments in this environmental impact statement (EIS) include an analysis of commitment-level alternatives. Impacts of the no-action alternative are also assessed. Supply options, which include combinations of electrical power purchases and hydropower operational scenarios reflecting different operations of the dams, are also assessed. The EIS evaluates the impacts of these scenarios relative to socioeconomics, air resources, water resources, ecological resources, cultural resources, land use, recreation, and visual resources.« less
FermiGrid - experience and future plans
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chadwick, K.; Berman, E.; Canal, P.
2007-09-01
Fermilab supports a scientific program that includes experiments and scientists located across the globe. In order to better serve this community, Fermilab has placed its production computer resources in a Campus Grid infrastructure called 'FermiGrid'. The FermiGrid infrastructure allows the large experiments at Fermilab to have priority access to their own resources, enables sharing of these resources in an opportunistic fashion, and movement of work (jobs, data) between the Campus Grid and National Grids such as Open Science Grid and the WLCG. FermiGrid resources support multiple Virtual Organizations (VOs), including VOs from the Open Science Grid (OSG), EGEE and themore » Worldwide LHC Computing Grid Collaboration (WLCG). Fermilab also makes leading contributions to the Open Science Grid in the areas of accounting, batch computing, grid security, job management, resource selection, site infrastructure, storage management, and VO services. Through the FermiGrid interfaces, authenticated and authorized VOs and individuals may access our core grid services, the 10,000+ Fermilab resident CPUs, near-petabyte (including CMS) online disk pools and the multi-petabyte Fermilab Mass Storage System. These core grid services include a site wide Globus gatekeeper, VO management services for several VOs, Fermilab site authorization services, grid user mapping services, as well as job accounting and monitoring, resource selection and data movement services. Access to these services is via standard and well-supported grid interfaces. We will report on the user experience of using the FermiGrid campus infrastructure interfaced to a national cyberinfrastructure--the successes and the problems.« less
Spatial and temporal dynamics of agricultural residue resources in the last 30 years in China.
Yang, Yanli; Zhang, Peidong; Yang, Xutong; Xu, Xiaoning
2016-12-01
The availability and distribution of biomass resources are important for the development of the bioenergy industry in a region. Biomass resources are abundant in China; however, the raw material is severely deficient, which makes the Chinese bioenergy industry an embarrassment and a contradiction. Unclear reserves and distribution and changing trends of biomass resources are the reason for this situation. A collection coefficient model of Chinese agricultural residue resources was established and the spatial and temporal pattern dynamics of agricultural residue resources in the last 30 years were analyzed. The results show that agricultural residue resources increased in stages from 1978 to 2011, including a rapid increase from 1978 to 1999, a significant fall from 2000 to 2004, and a slow increase from 2004 to 2011. Crops straw and livestock manure are the main ingredients of agricultural residue resources with proportions of 53-59% and 31-38%, respectively. However, the former has gradually decreased, while the latter is increasing. This mainly resulted from the strategic reorganization of the Chinese agriculture structure and the rapid development of large-scale livestock breeding and agricultural mechanization. Large regional differences existed in Chinese agricultural residue resources, and three distribution types formed, including resource-rich areas in North China, Northeast and Inner Mongolia, resource-limited areas in Central and Southwest China, and resource-poor areas along Northwest and Southeast coasts. This pattern is a reverse of the distributions of climatic conditions, water resources, economic development, human resources, and technological levels. Finally, it can be predicted that livestock manure and biomass conversion technology at low temperature will play increasingly significant roles in bioenergy industry development. © The Author(s) 2016.
Orris, Greta J.; Cocker, Mark D.; Dunlap, Pamela; Wynn, Jeff C.; Spanski, Gregory T.; Briggs, Deborah A.; Gass, Leila; Bliss, James D.; Bolm, Karen S.; Yang, Chao; Lipin, Bruce R.; Ludington, Stephen; Miller, Robert J.; Słowakiewicz, Mirosław
2014-01-01
This report describes a global, evaporite-related potash deposits and occurrences database and a potash tracts database. Chapter 1 summarizes potash resource history and use. Chapter 2 describes a global potash deposits and occurrences database, which contains more than 900 site records. Chapter 3 describes a potash tracts database, which contains 84 tracts with geology permissive for the presence of evaporite-hosted potash resources, including areas with active evaporite-related potash production, areas with known mineralization that has not been quantified or exploited, and areas with potential for undiscovered potash resources. Chapter 4 describes geographic information system (GIS) data files that include (1) potash deposits and occurrences data, (2) potash tract data, (3) reference databases for potash deposit and tract data, and (4) representative graphics of geologic features related to potash tracts and deposits. Summary descriptive models for stratabound potash-bearing salt and halokinetic potash-bearing salt are included in appendixes A and B, respectively. A glossary of salt- and potash-related terms is contained in appendix C and a list of database abbreviations is given in appendix D. Appendix E describes GIS data files, and appendix F is a guide to using the geodatabase.
ERIC Educational Resources Information Center
Hiestand, M. Ed.
2003-01-01
Discusses the importance of learning about diabetes and provides a list of ways to obtain this information. Different resources include videos, internet sites, books, cookbooks, and magazines. Provides a detailed list of each of the previous resources and recommends that people with or without diabetes make a concerted effort to educate…
A Case Study of the United States Navy’s Enterprise Resource Planning System
2006-06-01
incarnations, MRP-II added the capabilities of shop-floor management and distribution management activities. Later versions included the ability to manage ... finances , human resources, engineering, and project management. Enterprise Resource Planning systems were then developed as an integrated system
[Resources Unit, Edmonds School District.
ERIC Educational Resources Information Center
Edmonds School District 15, Lynnwood, WA.
This interdisciplinary program, developed for secondary students, contains 13 natural resource activities that can either be used directly in, or as a supplement to, curriculum in Science, Photography, Mathematics, Social Studies and English. The topics to be investigated include: raindrop impact, resource control, recycling, the world model,…
Missouri Autism Resource Guide. Fall 1998.
ERIC Educational Resources Information Center
Missouri State Dept. of Elementary and Secondary Education, Jefferson City.
This resource guide provides information on organizations, publications, legislation, and other resources relating to autism. Sections include: (1) commonly used disability acronyms and definitions; (2) the educational definition of autism; (3) the medical definition of autism; (4) special education offices and special services of the Missouri…
75 FR 75335 - Integration of Variable Energy Resources
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-02
... the facility owner or operator. This includes, for example, wind, solar thermal and photovoltaic, and... Commission recognized that intermittent resources, such as wind power, have a limited ability to control...\\ The Commission therefore exempted wind resources from certain sections of the LGIA and added Appendix...
Microform Resources on the Internet Project.
ERIC Educational Resources Information Center
Eichhorn, Sara J.; Yonezawa, Michael
1998-01-01
Summarizes information that will be used to describe microform sets on the University of California, Irvine's World Wide Web site for microform resources, including title, publisher, price, contents, index/bibliography, reviewed in, location/holdings, and Webpac site. Discusses staff/network resources, HTML/UNIX editors, and indexing/search…
75 FR 842 - Notice of Central Idaho Resource Advisory Committee Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-06
... Central Idaho Resource Advisory Committee Meeting AGENCY: Forest Service, USDA. ACTION: Notice of Meeting... National Forest's Central Idaho Resource Advisory Committee will conduct a business meeting which is open.... South Zone Office, Highway 93, Challis, Idaho. SUPPLEMENTARY INFORMATION: Agenda topics will include...
Remote sensing of wildland resources: A state-of-the-art review
Robert C. Aldrich
1979-01-01
A review, with literature citations, of current remote sensing technology, applications, and costs for wildland resource management, including collection, interpretation, and processing of data gathered through photographic and nonphotographic techniques for classification and mapping, interpretive information for specific applications, measurement of resource...
Code of Federal Regulations, 2014 CFR
2014-04-01
... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Procedure. 401.23 Section 401.23 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Water Resources Program § 401.23 Procedure. Each project included...
Code of Federal Regulations, 2010 CFR
2010-04-01
... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Procedure. 401.23 Section 401.23 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Water Resources Program § 401.23 Procedure. Each project included...
Code of Federal Regulations, 2012 CFR
2012-04-01
... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Procedure. 401.23 Section 401.23 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Water Resources Program § 401.23 Procedure. Each project included...
Code of Federal Regulations, 2013 CFR
2013-04-01
... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Procedure. 401.23 Section 401.23 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Water Resources Program § 401.23 Procedure. Each project included...
ERIC Educational Resources Information Center
Council for Exceptional Children, Reston, VA. Center for Special Education Technology.
The series of "Resource Inventories" is designed to encourage wider use of available information and services in the field of special education technology. A resource inventory is provided for each of 46 states of the United States. Each inventory includes directory information on public and private agencies and organizations that offer…
Code of Federal Regulations, 2011 CFR
2011-04-01
... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Procedure. 401.23 Section 401.23 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Water Resources Program § 401.23 Procedure. Each project included...
ERIC Educational Resources Information Center
Brown, Sally, Ed.; Smith, Brenda, Ed.
The selections in this book encompass a broad spectrum of resource-based learning experiences, and are intended to help teachers and administrators gain a better understanding of the concepts and devise effective and efficient ways to use these materials. Titles include: "Introducing Resources for Learning" (Sally Brown and Brenda…
Abbass-Dick, Jennifer; Xie, Fangli; Koroluk, Jaymie; Alcock Brillinger, Shelley; Huizinga, Joanne; Newport, Amber; Goodman, William M; Dennis, Cindy-Lee
2017-07-01
Traditionally breastfeeding education programs target mothers solely. The objective of this study was to design and pilot test an interactive eHealth breastfeeding co-parenting resource developed to target both mothers and fathers. eHealth resources provide an accessible and engaging format on which to educate parents and assist them in meeting their breastfeeding goals. Best practices to design such resources are not currently known. A three phase pilot study was conducted. The three phases included conducting a needs assessment, creating the resource and pilot testing the resource with mother, father and health care professionals to determine their perspectives regarding the usability and design of the prototype resource. The interactive prototype resource was designed to provide information to parents on breastfeeding and co-parenting, which included suggestions on how fathers can be involved and support breastfeeding and how the couples can work as a team to meet their breastfeeding goals. Setting: Recruitment took place in a health region in Southern Ontario, Canada between June 2014 and March 2015. Online questionnaires were completed by participants in all phases of the study. Participants (n=149) were pregnant or new mothers and their partners in the health region who read and speak English and had access to the internet and health care professionals who work with breastfeeding families in Ontario, Canada. A prototype eHealth breastfeeding co-parenting resource was developed based on maternal and paternal feedback from Phase I and utilized an interactive interface which included games and multimodal information delivery. The prototype eHealth resource was provided to the parents in Phase II and health care professionals in Phase III. The final resource was created based on feedback from these participants. The resource was pilot tested with new and expectant parents using pre- and post-test questionnaires which included measures for breastfeeding self-efficacy (Breastfeeding Self-Efficacy Short Form), infant feeding attitude (Iowa Infant Feeding Attitude Scale), breastfeeding knowledge (Breastfeeding Knowledge Questionnaire) and co-parenting relationship (Co-parenting Relationship Scale). Maternal and paternal breastfeeding self-efficacy and knowledge and infant feeding attitude scores all increased from pre-test to post-test. However, there was no difference in the co-parenting relationship scores from pretest to post-test. This study has used feedback from parents and health professionals to develop a prototype resource which appears to be effective in increasing parents' breastfeeding knowledge, attitude and self-efficacy. The prototype resource was rated positively by parents and health care providers. An eHealth breastfeeding co-parenting resource designed with input from the target population is an effective way of providing information to mothers and fathers. Further research with a randomized controlled design and more diverse populations is needed to determine effectiveness of the resource on breastfeeding duration and exclusivity. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Buxner, S.; Grier, J.; Meinke, B. K.; Gross, N. A.; Woroner, M.
2014-12-01
The NASA Science Education and Public Outreach (E/PO) Forums support the NASA Science Mission Directorate (SMD) and its E/PO community by enhancing the coherency and efficiency of SMD-funded E/PO programs. The Forums foster collaboration and partnerships between scientists with content expertise and educators with pedagogy expertise. We will present tools to engage and resources to support scientists' engagement in E/PO efforts. Scientists can get connected to educators and find support materials and links to resources to support their E/PO work through the online SMD E/PO community workspace (http://smdepo.org) The site includes resources for scientists interested in E/PO including one page guides about "How to Get Involved" and "How to Increase Your Impact," as well as the NASA SMD Scientist Speaker's Bureau to connect scientists to audiences across the country. Additionally, there is a set of online clearinghouses that provide ready-made lessons and activities for use by scientists and educators: NASA Wavelength (http://nasawavelength.org/) and EarthSpace (http://www.lpi.usra.edu/earthspace/). The NASA Forums create and partner with organizations to provide resources specifically for undergraduate science instructors including slide sets for Earth and Space Science classes on the current topics in astronomy and planetary science. The Forums also provide professional development opportunities at professional science conferences each year including AGU, LPSC, AAS, and DPS to support higher education faculty who are teaching undergraduate courses. These offerings include best practices in instruction, resources for teaching planetary science and astronomy topics, and other special topics such as working with diverse students and the use of social media in the classroom. We are continually soliciting ways that we can better support scientists' efforts in effectively engaging in E/PO. Please contact Sanlyn Buxner (buxner@psi.edu) or Jennifer Grier (jgrier@psi.edu) to give us feedback on these resources or others you would like to see.
Cocker, Mark D.; Orris, Greta J.; Wynn, Jeff
2016-01-01
During the past 15 yr, the global requirement for fertilizers has grown considerably, mainly due to demand by a larger and wealthier world population for more and higher-quality food. The demand and price for potash as a primary fertilizer ingredient have increased in tandem, because of the necessity to increase the quantity and quality of food production on the decreasing amount of available arable land. The primary sources of potash are evaporates, which occur mainly in marine salt basins and a few brine-bearing continental basins. World potash resources are large, but distribution is inequitable and not presently developed in countries where population and food requirements are large and increasing. There is no known substitute for potash in fertilizer, so knowledge of the world’s potash resources is critical for a sustainable future. The U.S. Geological Survey recently completed a global assessment of evaporite-hosted potash resources, which included a geographic information system–based inventory of known potash resources. This assessment included permissive areas or tracts for undiscovered resources at a scale of 1:1,000,000. Assessments of undiscovered potash resources were conducted for a number of the world’s evaporite-hosted potash basins. The data collected provide a major advance in our knowledge of global potash resources that did not exist prior to this study. The two databases include: (1) potash deposits and occurrences, and (2) potash tracts (basins that contain these deposits and occurrences and potentially undiscovered potash deposits). Data available include geology, mineralogy, grade, tonnage, depth, thickness, areal extent, and structure, as well as numerous pertinent references.
Aliu, Oluseyi; Corlew, Scott D; Heisler, Michele E; Pannucci, Christopher J; Chung, Kevin C
2014-01-01
Surgical volunteer organizations (SVOs) focus considerable resources on addressing the backlog of cases in low-resource countries. This model of service may perpetuate dependency. Efforts should focus on models that establish independence in providing surgical care. Independence could be achieved through surgical capacity building. However, there has been scant discussion in literature on SVO involvement in surgical capacity building. Using qualitative methods, we evaluated the perspectives of surgeons with extensive volunteer experience in low-resource countries. We collected data through in-depth interviews that centered on SVOs using task shifting as a tool for surgical capacity building. Some of the key themes from our analysis include the ethical ramifications of task shifting, the challenges of addressing technical and clinical education in capacity building for low-resource settings, and the allocation of limited volunteer resources toward surgical capacity building. These themes will be the foundation of subsequent studies that will focus on other stakeholders in surgical capacity building including host communities and SVO administrators.
Global Health: Pediatric Neurology.
Bearden, David R; Ciccone, Ornella; Patel, Archana A
2018-04-01
Neurologic disorders contribute significantly to both morbidity and mortality among children in resource-limited settings, but there are a few succinct studies summarizing the epidemiology of neurologic disorders in these settings. A review of available literature was performed to identify data on the prevalence, etiology, outcomes, and treatment of neurologic disorders in children in resource-limited settings. The burden of neurologic disorders in children is high in resource-limited settings. Barriers to optimal care include lack of trained personnel, limited access to diagnostic technology, and limited availability of drugs used to treat common conditions. Several solutions have been suggested to deal with these challenges including increased collaborations to train neurologists willing to practice in resource-limited settings and increased training of physician extenders or community health workers. Further studies are necessary to improve our understanding of the epidemiology of neurologic disorders in resource-limited settings. Future epidemiologic studies should incorporate multiple countries in resource-limited settings and utilize standardized definitions and methodologies to enable comparison across regions. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
Final Technical Report: Renewable Energy Feasibility Study and Resources Assessment
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rivero, Mariah
In March 2011, the U.S. Department of Energy (DOE) awarded White Pine County, Nevada, a grant to assess the feasibility of renewable resource-related economic development activities in the area. The grant project included a public outreach and training component and was to include a demonstration project; however, the demonstration project was not completed due to lack of identification of an entity willing to locate a project in White Pine County. White Pine County completed the assessment of renewable resources and a feasibility study on the potential for a renewable energy-focused economic sector within the County. The feasibility study concluded "allmore » resources studied were present and in sufficient quantity and quality to warrant consideration for development" and there were varying degrees of potential economic impact based on the resource type and project size. The feasibility study and its components were to be used as tools to attract potential developers and other business ventures to the local market. White Pine County also marketed the County’s resources to the renewable energy business community in an effort to develop contracts for demonstration projects. The County also worked to develop partnerships with local educational institutions, including the White Pine County School District, conducted outreach and training for the local community.« less
Altizer, Sonia. M.; Becker, Daniel J.; Epstein, Jonathan H.; Forbes, Kristian M.; Gillespie, Thomas R.; Hall, Richard J.; Hawley, Dana; Hernandez, Sonia M.; Martin, Lynn B.; Plowright, Raina K.; Satterfield, Dara A.; Streicker, Daniel G.
2018-01-01
Human-provided resource subsidies for wildlife are diverse, common, and have profound consequences for wildlife–pathogen interactions, as demonstrated by papers in this themed issue spanning empirical, theoretical, and management perspectives from a range of study systems. Contributions cut across scales of organization, from the within-host dynamics of immune function, to population-level impacts on parasite transmission, to landscape- and regional-scale patterns of infection. In this concluding paper, we identify common threads and key findings from author contributions, including the consequences of resource subsidies for (i) host immunity; (ii) animal aggregation and contact rates; (iii) host movement and landscape-level infection patterns; and (iv) inter-specific contacts and cross-species transmission. Exciting avenues for future work include studies that integrate mechanistic modeling and empirical approaches to better explore cross-scale processes, and experimental manipulations of food resources to quantify host and pathogen responses. Work is also needed to examine evolutionary responses to provisioning, and ask how diet-altered changes to the host microbiome influence infection processes. Given the massive public health and conservation implications of anthropogenic resource shifts, we end by underscoring the need for practical recommendations to manage supplemental feeding practices, limit human–wildlife conflicts over shared food resources, and reduce cross-species transmission risks, including to humans. PMID:29531154
Gabbard, Joseph L.; Shukla, Maulik; Sobral, Bruno
2010-01-01
Systems biology and infectious disease (host-pathogen-environment) research and development is becoming increasingly dependent on integrating data from diverse and dynamic sources. Maintaining integrated resources over long periods of time presents distinct challenges. This paper describes experiences and lessons learned from integrating data in two five-year projects focused on pathosystems biology: the Pathosystems Resource Integration Center (PATRIC, http://patric.vbi.vt.edu/), with a goal of developing bioinformatics resources for the research and countermeasures development communities based on genomics data, and the Resource Center for Biodefense Proteomics Research (RCBPR, http://www.proteomicsresource.org/), with a goal of developing resources based on the experiment data such as microarray and proteomics data from diverse sources and technologies. Some challenges include integrating genomic sequence and experiment data, data synchronization, data quality control, and usability engineering. We present examples of a variety of data integration problems drawn from our experiences with PATRIC and RBPRC, as well as open research questions related to long term sustainability, and describe the next steps to meeting these challenges. Novel contributions of this work include (1) an approach for addressing discrepancies between experiment results and interpreted results and (2) expanding the range of data integration techniques to include usability engineering at the presentation level. PMID:20491070
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bartsch-Winkler, S.; Dickerson, R.P.; Barton, H.W.
1990-09-01
This paper reports on the San Rafael Swell Wilderness Study areas, which includes the Muddy Creek, Crack Canyon, San Rafael Reef, Mexican Mountain, and Sids Mountain Wilderness Study Areas, in Emery County, south-central Utah. Within and near the Crack Canyon Wilderness Study Area are identified subeconomic uranium and vanadium resources. Within the Carmel Formation are inferred subeconomic resources of gypsum in the Muddy Creek, San Rafael Reef, and Sids Mountain Wilderness Study Areas. Other commodities evaluated include geothermal energy, gypsum, limestone, oil and gas, sand and gravel, sandstone, semiprecious gemstones, sulfur petrified wood, and tar sand.
NASA Astrophysics Data System (ADS)
Maksimov, N. V.; Tikhomirov, G. V.; Golitsyna, O. L.
2017-01-01
The main problems and circumstances that influence the processes of creating effective knowledge management systems were described. These problems particularly include high species diversity of instruments for knowledge representation, lack of adequate lingware, including formal representation of semantic relationships. For semantic data descriptions development a conceptual model of the subject area and a conceptual-lexical system should be designed on proposals of ISO-15926 standard. It is proposed to conduct an information integration of educational and production processes on the basis of information systems technologies. Integrated knowledge management system information environment combines both traditional information resources and specific information resources of subject domain including task context and implicit/tacit knowledge.
Decentralized Real-Time Scheduling
1990-08-01
must provide several alternative resource management policies, including FIFO and deadline queueing for shared resources that are not available. 5...When demand exceeds the supply of shared resources (even within a single switch), some calls cannot be completed. In that case, a call’s priority...associated chiefly with the need to manage resources in a timely and decentralized fashion. The Alpha programming model permits the convenient expression of
NREL: Renewable Resource Data Center - Wind Resource Information
and Actual Wind Turbine Sites (September 1982) and a Wind Energy Resource Atlas of the United States Wind Resource Information Photo of five wind turbines at the Nine Canyon Wind Project. The Nine Canyon Wind Project in Benton County, Washington, includes 37 wind turbines and 48 MW of capacity
Resource Directory: Migrant and Indian Exceptional Children.
ERIC Educational Resources Information Center
Indian Education Training, Inc., Albuquerque, NM.
Designed as a supplementary resource for special education directors and teachers, this directory covers a five state area which includes Arizona, California, New Mexico, Texas, and Washington, and concentrates on targeted resources for Indian and migrant children with exceptional needs. After general discussions of services available for migrant…
Job Power: Career Management Resources for Librarians.
ERIC Educational Resources Information Center
Wein, Terren Ilana; Gagnon, Marjorie; Barrett, Maura
2003-01-01
Discusses prospects in the job market for information professionals and emphasizes the need to be flexible. Highlights include examining the gap in skills and knowledge that may be needed; resources for resumes; resources for networking and interview preparation; sources of job postings; general career tools; international opportunities; career…
Medical Student Preferences for Self-Directed Study Resources in Gross Anatomy
ERIC Educational Resources Information Center
Choi-Lundberg, Derek L.; Low, Tze Feng; Patman, Phillip; Turner, Paul; Sinha, Sankar N.
2016-01-01
Gross anatomy instruction in medical curricula involve a range of resources and activities including dissection, prosected specimens, anatomical models, radiological images, surface anatomy, textbooks, atlases, and computer-assisted learning (CAL). These resources and activities are underpinned by the expectation that students will actively engage…
Editor's Choice 2008: Selected Online Learning Resources
ERIC Educational Resources Information Center
Dringus, Laurie P.
2008-01-01
This article is an annual compilation of useful resources that pertain to the field of online learning and uses of the Internet for instructional delivery. Updates were made to this list since last year's publishing. Resources are organized into several categories, including texts, journals, and Web sites.
Educating Librarians and Information Resource Managers: Differing Management Perspectives?
ERIC Educational Resources Information Center
Bouthillier, France
1993-01-01
Examines differences between library management and information resource management (IRM). Highlights include a historical perspective of library management education and IRM; the organizational perspective of library management and the emphasis of information as a resource in IRM; library management and advances in information technology; and…
HEATH National Resource Directory on Postsecondary Education and Disability 1996.
ERIC Educational Resources Information Center
Barr, Vickie M., Ed.
This biennial directory lists a variety of selected resources in the field of postsecondary education and disability, including independent organizations, governmental agencies, and technology-related resources. Listings usually provide name (or title), address, electronic-mail address, telephone number, facsimile number, and a brief description.…
Partnerships panel: natural, resource partnerships: literature synthesis and research agenda
Steve Selin; Nancy Myers
1995-01-01
This paper presents a summary of an annotated bibliography on natural resource partnerships. Resource areas and management functions addressed in the partnership literature are examined. Partnership research is summarized and broken into categories including: Partnership outcomes, assessing the potential for partnerships, characteristics of successful partnerships,...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-30
... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER11-2154-000] Twin Eagle Resource Management, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for... proceeding, of Twin Eagle Resource Management, LLC's [[Page 74039
18 CFR 708.4 - Required programs and reports.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Required programs and reports. 708.4 Section 708.4 Conservation of Power and Water Resources WATER RESOURCES COUNCIL UPPER... shall include survey research, program evaluation, and information/education activities as described in...
Selected Educational Resources in Interpersonal Communication.
ERIC Educational Resources Information Center
Yamauchi, Joanne S.
1974-01-01
The rapid growth in the field of interpersonal communication is reflected in both the introduction of courses dealing with the personalized involvement of people with each other and the prolific output of related educational resources. Specific representative samples of current resource selections include four texts dealing solely with…
43 CFR 11.84 - Damage determination phase-implementation guidance.
Code of Federal Regulations, 2011 CFR
2011-10-01
... the damage assessment. (2) Natural resource damages are the residual to be determined by incorporating... estimates of natural recovery rates as well as recovery rates that reflect management actions or resource... actions or resource acquisitions, including a “No Action-Natural Recovery” alternative. After the recovery...
Development of Electronic Resources across Networks in Thailand.
ERIC Educational Resources Information Center
Ratchatavorn, Phandao
2002-01-01
Discusses the development of electronic resources across library networks in Thailand to meet user needs, particularly electronic journals. Topics include concerns about journal access; limited budgets for library acquisitions of journals; and sharing resources through a centralized database system that allows Web access to journals via Internet…
Searching U.S. Patents: Core Collection and Suggestions for Service.
ERIC Educational Resources Information Center
Harwell, Kevin R.
1993-01-01
Provides fundamental information about patents, describes effective and affordable reference resources, and discusses specific issues in providing patent information services to inventors and other patrons. Basic resources, including CD-ROM products, patent classification and searching resources, and other search tools are described in an…
Immersive Education, an Annotated Webliography
ERIC Educational Resources Information Center
Pricer, Wayne F.
2011-01-01
In this second installment of a two-part feature on immersive education a webliography will provide resources discussing the use of various types of computer simulations including: (a) augmented reality, (b) virtual reality programs, (c) gaming resources for teaching with technology, (d) virtual reality lab resources, (e) virtual reality standards…
Aviation & Space Education: A Teacher's Resource Guide.
ERIC Educational Resources Information Center
Texas State Dept. of Aviation, Austin.
This resource guide contains information on curriculum guides, resources for teachers, computer software and computer related programs, audio/visual presentations, model aircraft and demonstration aids, training seminars and career education, and an aerospace bibliography for primary grades. Each entry includes all or some of the following items:…
In-Situ Resource Utilization (ISRU) Capability Roadmap Progress Review
NASA Technical Reports Server (NTRS)
Sanders, Gerald B.; Duke, Michael
2005-01-01
A progress review on In-Situ Resource Utilization (ISRU) capability is presented. The topics include: 1) In-Situ Resource Utilization (ISRU) Capability Roadmap: Level 1; 2) ISRU Emphasized Architecture Overview; 3) ISRU Capability Elements: Level 2 and below; and 4) ISRU Capability Roadmap Wrap-up.
Teaching for Global Perspective: A Resource Handbook.
ERIC Educational Resources Information Center
Roach, Patricia Betts, Ed.
This state resource guide of approximately 250 lesson units for teaching global studies provides 18 topics and from 3-12 lessons for each topic. The topics include global perspective, using models, balance of power, conflict, development, global environment, global resources, global trade, human rights, hunger, ideologies, international…
75 FR 63254 - Notice of Actions Taken at September 16, 2010, Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-14
... water resources projects; (2) approved and tabled certain water resources projects, including approval of one project involving diversions into the basin; and (3) rescinded approval for two water resources projects. DATES: September 16, 2010. ADDRESSES: Susquehanna River Basin Commission, 1721 N. Front...
Coordination and collaboration to document the global cotton germplasm resources
USDA-ARS?s Scientific Manuscript database
Coordinated efforts to collect and maintain cotton genetic resources have increased over the last 100 years to insure the worldwide economic value of cotton fiber and cotton byproducts. The classified genetic resources of cotton are extensive and include five tetraploid species in the primary gene ...
Community College Finance Resource Development. UCLA Community College Bibliography
ERIC Educational Resources Information Center
Carducci, Rozana
2006-01-01
The references in this bibliography provide an overview of recent scholarship on community college finance and resource development. In addition to documents that present a national portrait and comparative analysis of community college funding models and resource management practices, this bibliography also includes recent publications that…
NASA In-Situ Resource Utilization Project-and Seals Challenges
NASA Technical Reports Server (NTRS)
Sacksteder, Kurt; Linne, Diane
2006-01-01
A viewgraph presentation on NASA's In-Situ Resource Utilization Project and Seals Challenges is shown. The topics include: 1) What Are Space Resources?; 2) Space Resource Utilization for Exploration; 3) ISRU Enables Affordable, Sustainable & Flexible Exploration; 4) Propellant from the Moon Could Revolutionize Space Transportation; 5) NASA ISRU Capability Roadmap Study, 2005; 6) Timeline for ISRU Capability Implementation; 7) Lunar ISRU Implementation Approach; 8) ISRU Technical-to-Mission Capability Roadmap; 9) ISRU Resources & Products of Interest; and 10) Challenging Seals Requirements for ISRU.
Joint Workshop on New Technologies for Lunar Resource Assessment
NASA Technical Reports Server (NTRS)
Elphic, Rick C. (Editor); Mckay, David S. (Editor)
1992-01-01
The workshop included talks on NASA's and DOE's role in Space Exploration Initiative, lunar geology, lunar resources, the strategy for the first lunar outpost, and an industry perspective on lunar resources. The sessions focused on four major aspects of lunar resource assessment: (1) Earth-based remote sensing of the Moon; (2) lunar orbital remote sensing; (3) lunar lander and roving investigations; and (4) geophysical and engineering consideration. The workshop ended with a spirited discussion of a number of issues related to resource assessment.
Genomics Community Resources | Informatics Technology for Cancer Research (ITCR)
To facilitate genomic research and the dissemination of its products, National Human Genome Research Institute (NHGRI) supports genomic resources that are crucial for basic research, disease studies, model organism studies, and other biomedical research. Awards under this FOA will support the development and distribution of genomic resources that will be valuable for the broad research community, using cost-effective approaches. Such resources include (but are not limited to) databases and informatics resources (such as human and model organism databases, ontologies, and analysi
The evolution of Crew Resource Management training in commercial aviation
NASA Technical Reports Server (NTRS)
Helmreich, R. L.; Merritt, A. C.; Wilhelm, J. A.
1999-01-01
In this study, we describe changes in the nature of Crew Resource Management (CRM) training in commercial aviation, including its shift from cockpit to crew resource management. Validation of the impact of CRM is discussed. Limitations of CRM, including lack of cross-cultural generality are considered. An overarching framework that stresses error management to increase acceptance of CRM concepts is presented. The error management approach defines behavioral strategies taught in CRM as error countermeasures that are employed to avoid error, to trap errors committed, and to mitigate the consequences of error.
Water Resources Data for California, 1969; Part 2: Water Quality Records
1970-01-01
Water-resources investigations of the U.S. Geological Survey include the collection of water-quality data on the chemical and physical characteristics of surface and ground-water supplies of the Nation. Theses data for the 1969 water year for the quality of surface water in California are presented in this report. Data for a few water-quality stations in bordering States are also included. The data were collected by the Water Resources Division of the Geological Survey under the direction of R. Stanley Lord, district chief, Menlo Park, Calif.