Sample records for revealed noticeable differences

  1. Noticing Grammar in L2 Writing and Problem-Solving Strategies

    ERIC Educational Resources Information Center

    Geist, Monika

    2017-01-01

    Noticing plays an important role for second language acquisition. Since the formulation of the output hypothesis (Swain, 1985), it has been proven that producing output can lead to noticing. Studies on noticing have revealed little focus on grammar, and an in-depth investigation of grammar noticing has not been conducted so far. Studies into…

  2. 78 FR 17744 - Culturally Significant Objects Imported for Exhibition Determinations: “Maya: Hidden Worlds...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ... DEPARTMENT OF STATE [Public Notice 8249] Culturally Significant Objects Imported for Exhibition Determinations: ``Maya: Hidden Worlds Revealed'' SUMMARY: Notice is hereby given of the following determinations... Worlds Revealed,'' imported from abroad for temporary exhibition within the United States, are of...

  3. Putting the "th" in Tenths: Providing Place-Value Labels Helps Reveal the Structure of Our Base-10 Numeral System

    ERIC Educational Resources Information Center

    Loehr, Abbey M.; Rittle-Johnson, Bethany

    2017-01-01

    Research has demonstrated that providing labels helps children notice key features of examples. Much less is known about how different labels impact children's ability to make inferences about the structure underlying mathematical notation. We tested the impact of labeling decimals such as 0.34 using formal place-value labels ("3 tenths and 4…

  4. Does working memory capacity predict cross-modally induced failures of awareness?

    PubMed

    Kreitz, Carina; Furley, Philip; Simons, Daniel J; Memmert, Daniel

    2016-01-01

    People often fail to notice unexpected stimuli when they are focusing attention on another task. Most studies of this phenomenon address visual failures induced by visual attention tasks (inattentional blindness). Yet, such failures also occur within audition (inattentional deafness), and people can even miss unexpected events in one sensory modality when focusing attention on tasks in another modality. Such cross-modal failures are revealing because they suggest the existence of a common, central resource limitation. And, such central limits might be predicted from individual differences in cognitive capacity. We replicated earlier evidence, establishing substantial rates of inattentional deafness during a visual task and inattentional blindness during an auditory task. However, neither individual working memory capacity nor the ability to perform the primary task predicted noticing in either modality. Thus, individual differences in cognitive capacity did not predict failures of awareness even though the failures presumably resulted from central resource limitations. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Dynamics and asymptotics of correlations in a many-body localized system

    NASA Astrophysics Data System (ADS)

    Campbell, Steve; Power, Matthew J. M.; De Chiara, Gabriele

    2017-08-01

    We examine the dynamics of nearest-neighbor bipartite concurrence and total correlations in the spin-1/2 XXZ model with random fields. We show, starting from factorized random initial states, that the concurrence can suffer entanglement sudden death in the long time limit and therefore may not be a useful indicator of the properties of the system. In contrast, we show that the total correlations capture the dynamics more succinctly, and further reveal a fundamental difference in the dynamics governed by the ergodic versus many-body localized phases, with the latter exhibiting dynamical oscillations. Finally, we consider an initial state composed of several singlet pairs and show that by fixing the correlation properties, while the dynamics do not reveal noticeable differences between the phases, the long-time values of the correlation measures appear to indicate the critical region.

  6. Noticing numeracy now! Examining changes in preservice teachers' noticing, knowledge, and attitudes

    NASA Astrophysics Data System (ADS)

    Fisher, Molly H.; Thomas, Jonathan; Schack, Edna O.; Jong, Cindy; Tassell, Janet

    2018-06-01

    This study examined the impact of an intervention, focused on professional noticing of children's conceptual development in whole number and arithmetic reasoning, on preservice elementary teachers' (PSETs') professional noticing skills, attitudes toward mathematics, and mathematical knowledge for teaching mathematics. A video-based professional noticing module, situated in the pedagogies of practice framework, was used with 224 PSETs from five universities. Comparison data was also collected with similar groups not participating in the instructional module. Through pre- and post-assessments, findings indicated that PSETs can develop sound professional noticing skills as a result of participation in a video-based module. The impact on attitudes toward mathematics was less convincing as significant changes were revealed in intervention as well as comparison groups. We hypothesized the potential for professional noticing of children's mathematical thinking to serve as a mechanism for increasing the capabilities of PSETs to negotiate the complexities of mathematics teaching and learning; however, mathematics knowledge for teaching showed no significant increase for either group.

  7. An empirical investigation on the forecasting ability of mallows model averaging in a macro economic environment

    NASA Astrophysics Data System (ADS)

    Yin, Yip Chee; Hock-Eam, Lim

    2012-09-01

    This paper investigates the forecasting ability of Mallows Model Averaging (MMA) by conducting an empirical analysis of five Asia countries, Malaysia, Thailand, Philippines, Indonesia and China's GDP growth rate. Results reveal that MMA has no noticeable differences in predictive ability compared to the general autoregressive fractional integrated moving average model (ARFIMA) and its predictive ability is sensitive to the effect of financial crisis. MMA could be an alternative forecasting method for samples without recent outliers such as financial crisis.

  8. The Motor-Proficiency-Test for children between 4 and 6 years of age (MOT 4-6): an investigation of its suitability in Greece.

    PubMed

    Kambas, A; Venetsanou, F; Giannakidou, D; Fatouros, I G; Avloniti, A; Chatzinikolaou, A; Draganidis, D; Zimmer, R

    2012-01-01

    Given the negative influence of motor difficulties on people's quality of life their early identification seems to be crucial and consequently the information provided by a sound assessment tool is of great importance. The aim of this study was to examine the suitability of the MOT 4-6 (Zimmer & Volkamer, 1987) for use with preschoolers in Greece. Seven hundred and seventy-eight Greek children aged 48-71 months participated in the study. The two-way ANOVA used on total MOT performance revealed significant differences among the age groups formed in preschool age within Greeks, while boys' and girls' scores were quite similar. From the comparisons of Greeks' scores with the German standardization sample's ones, statistically significant differences were found in two age groups. However according to the Cohen's d effect size they were not of great importance. The distribution of Greeks' scores according to the test cut-offs, revealed that the MOT can differentiate all levels of performance, although a slight deviation from the distribution of Germans' scores was noticed. Finally, both the test-retest reliability and internal consistency of the test were found to be excellent. The MOT 4-6 seems to be a valuable motor assessment tool for Greek preschoolers. Regarding its norms, despite the minor differences that were noticed between the motor development of Greek and German preschoolers, their adjustment was thought to be unnecessary. Instead of lowering the norms, efforts for preventing the motor performance decline should be enhanced. Copyright © 2012 Elsevier Ltd. All rights reserved.

  9. Comparing Amino Acid Abundances and Distributions Across Carbonaceous Chondrite Groups

    NASA Technical Reports Server (NTRS)

    Burton, Aaron S.; Callahan, Michael P.; Glavin, Daniel P.; Elsila, Jamie E.; Dworkin, Jason P.

    2012-01-01

    Meteorites are grouped according to bulk properties such as chemical composition and mineralogy. These parameters can vary significantly among the different carbonaceous chondrite groups (CI, CM, CO, CR, CH, CB, CV and CK). We have determined the amino acid abundances of more than 30 primary amino acids in meteorites from each of the eight groups, revealing several interesting trends. There are noticeable differences in the structural diversity and overall abundances of amino acids between meteorites from the different chondrite groups. Because meteorites may have been an important source of amino acids to the prebiotic Earth and these organic compounds are essential for life as we know it, the observed variations of these molecules may have been important for the origins of life.

  10. Fate of THMs and HAAs in low TOC surface water.

    PubMed

    Kim, Jinkeun

    2009-02-01

    A total of 30 conventional surface water treatment plants (WTPs) implementing prechlorination and postchlorination simultaneously from different regions in Korea were investigated to assess formation and removal of THMs and HAA(5). All water was low in total organic carbon (TOC) ranging from 0.74 to 6.20 mg/L with an average of 1.63 mg/L. The ranges of THMs and HAA(5) levels were 4.5-84.3 microg/L and 1.5-90.8 microg/L, respectively. THMs concentration was more sensitive to water temperature than HAA(5) and the ratio of THMs in summer over winter was 2.06. The sum of dichloroacetic acid (DCAA) and trichloroacetic acid (TCAA) was 97% of HAA(5). The extent of formation and speciation of DBPs varied greatly by season and geography. The concentration of DCAA and TCAA of the finished water was comparable on a yearly base, but more TCAA was noticed in summer and the opposite trend was noticed in winter. This can be caused by different biodegradability in the sand filter between DCAA and TCAA that formed through prechlorination. Investigation on the removal of preformed DBPs in the GAC filter-adsorber (FA) revealed that breakthrough of THMs and HAA(5) was noticed after 3 months of operation. However, gradual improvement (>90%) in HAA(5) removal was observed again after breakthrough, which could be attributable to biodegradation. Heterotrophic plate counts confirmed active biological activity in the GAC FA.

  11. The Influence of Attention Set, Working Memory Capacity, and Expectations on Inattentional Blindness.

    PubMed

    Kreitz, Carina; Furley, Philip; Memmert, Daniel; Simons, Daniel J

    2016-04-01

    The probability of inattentional blindness, the failure to notice an unexpected object when attention is engaged on some primary task, is influenced by contextual factors like task demands, features of the unexpected object, and the observer's attention set. However, predicting who will notice an unexpected object and who will remain inattentionally blind has proven difficult, and the evidence that individual differences in cognition affect noticing remains ambiguous. We hypothesized that greater working memory capacity might modulate the effect of attention sets on noticing because working memory is associated with the ability to focus attention selectively. People with greater working memory capacity might be better able to attend selectively to target items, thereby increasing the chances of noticing unexpected objects that were similar to the attended items while decreasing the odds of noticing unexpected objects that differed from the attended items. Our study (N = 120 participants) replicated evidence that task-induced attention sets modulate noticing but found no link between noticing and working memory capacity. Our results are largely consistent with the idea that individual differences in working memory capacity do not predict noticing of unexpected objects in an inattentional blindness task. © The Author(s) 2015.

  12. Out of Mind, Out of Sight: Unexpected Scene Elements Frequently Go Unnoticed Until Primed.

    PubMed

    Slavich, George M; Zimbardo, Philip G

    2013-12-01

    The human visual system employs a sophisticated set of strategies for scanning the environment and directing attention to stimuli that can be expected given the context and a person's past experience. Although these strategies enable us to navigate a very complex physical and social environment, they can also cause highly salient, but unexpected stimuli to go completely unnoticed. To examine the generality of this phenomenon, we conducted eight studies that included 15 different experimental conditions and 1,577 participants in all. These studies revealed that a large majority of participants do not report having seen a woman in the center of an urban scene who was photographed in midair as she was committing suicide. Despite seeing the scene repeatedly, 46 % of all participants failed to report seeing a central figure and only 4.8 % reported seeing a falling person. Frequency of noticing the suicidal woman was highest for participants who read a narrative priming story that increased the extent to which she was schematically congruent with the scene. In contrast to this robust effect of inattentional blindness , a majority of participants reported seeing other peripheral objects in the visual scene that were equally difficult to detect, yet more consistent with the scene. Follow-up qualitative analyses revealed that participants reported seeing many elements that were not actually present, but which could have been expected given the overall context of the scene. Together, these findings demonstrate the robustness of inattentional blindness and highlight the specificity with which different visual primes may increase noticing behavior.

  13. What you "see" is how you communicate: Medical students' meaning making of a patient's vignette.

    PubMed

    Karnieli-Miller, Orit; Michael, Keren; Eidelman, Shmuel; Meitar, Dafna

    2018-04-10

    To examine how medical students notice issues in a vignette and construct their meaning, and how this construction influences their plan to communicate with the patient. Following a breaking bad news course for 112 senior medical students, we qualitatively analyzed the participants' written descriptions of the issues they noticed as requiring special attention, using an Immersion/Crystallization iterative consensus process. Different students noticed different issues, but no-one noticed all 19 planted issues (Mean of issues noticed by students = 6.77; SD = 2.29). The students wrote about the issues in 46 different ways, representing the diverse meanings they ascribed, ranging from identifying, through inferring, to interpreting while jumping to conclusions. Moreover, for some issues, some students focused on the patient whereas others focused on the physician or the physician-patient relationship. Noticing issues led to preparing for communication with the patient. Noticing the issues and the subsequent meaning-making process facilitated the preparation to address them in the envisioned encounter. When teaching communication skills, it would be helpful to focus on increasing students' awareness of the issues they notice or fail to notice and their personal meaning-making process. This might reduce bias and enhance their preparation for effective patient-centered communication. Copyright © 2018 Elsevier B.V. All rights reserved.

  14. Inattentional Blindness and Individual Differences in Cognitive Abilities.

    PubMed

    Kreitz, Carina; Furley, Philip; Memmert, Daniel; Simons, Daniel J

    2015-01-01

    People sometimes fail to notice salient unexpected objects when their attention is otherwise occupied, a phenomenon known as inattentional blindness. To explore individual differences in inattentional blindness, we employed both static and dynamic tasks that either presented the unexpected object away from the focus of attention (spatial) or near the focus of attention (central). We hypothesized that noticing in central tasks might be driven by the availability of cognitive resources like working memory, and that noticing in spatial tasks might be driven by the limits on spatial attention like attention breadth. However, none of the cognitive measures predicted noticing in the dynamic central task or in either the static or dynamic spatial task. Only in the central static task did working memory capacity predict noticing, and that relationship was fairly weak. Furthermore, whether or not participants noticed an unexpected object in a static task was only weakly associated with their odds of noticing an unexpected object in a dynamic task. Taken together, our results are largely consistent with the notion that noticing unexpected objects is driven more by stochastic processes common to all people than by stable individual differences in cognitive abilities.

  15. Inattentional Blindness and Individual Differences in Cognitive Abilities

    PubMed Central

    Kreitz, Carina; Furley, Philip; Memmert, Daniel; Simons, Daniel J.

    2015-01-01

    People sometimes fail to notice salient unexpected objects when their attention is otherwise occupied, a phenomenon known as inattentional blindness. To explore individual differences in inattentional blindness, we employed both static and dynamic tasks that either presented the unexpected object away from the focus of attention (spatial) or near the focus of attention (central). We hypothesized that noticing in central tasks might be driven by the availability of cognitive resources like working memory, and that noticing in spatial tasks might be driven by the limits on spatial attention like attention breadth. However, none of the cognitive measures predicted noticing in the dynamic central task or in either the static or dynamic spatial task. Only in the central static task did working memory capacity predict noticing, and that relationship was fairly weak. Furthermore, whether or not participants noticed an unexpected object in a static task was only weakly associated with their odds of noticing an unexpected object in a dynamic task. Taken together, our results are largely consistent with the notion that noticing unexpected objects is driven more by stochastic processes common to all people than by stable individual differences in cognitive abilities. PMID:26258545

  16. LC-QTOF-MS Analysis and Activity Profiles of Popular Antioxidant Dietary Supplements in Terms of Quality Control

    PubMed Central

    Baj, Tomasz; Sawicki, Rafal; Wanat, Aleksandra; Wojtanowski, Krzysztof Kamil; Ginalska, Grazyna; Zgorka, Grazyna; Szymanska, Jolanta

    2017-01-01

    The dietary supplements with claimed antioxidant activity constitute a substantial part of the dietary supplement market. In this study, we performed the LC-QTOF-MS analysis and investigated the activity profiles of popular antioxidant dietary supplements from different chemical groups in terms of quality control. The commonly used antioxidant tests and statistical analysis revealed that substantial part of the results was comparable if 1 g sample was considered, but while comparing single and daily doses, significant differences in antioxidant values were noticed in all assays. The best antioxidant activity was obtained in ORAC assay (from 142 to 13814 μM of Trolox equivalents per 1 g of sample), and the strongest correlation occurred between TPC and ORAC. The LC-QTOF-MS analysis revealed that catechins were present in samples having the best antioxidant activity and that dietary supplements showing the weakest activity contained very small amount of any chemical constituents. PMID:28642814

  17. 76 FR 55296 - Airworthiness Directives; Bombardier, Inc. Model DHC-8-300 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-07

    .... Model DHC-8-300 Series Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of... been found cracked on DHC-8 Series 300 aircraft. Investigation revealed that the failure of the support... manufactured using sheet metal have been found cracked on DHC-8 Series 300 aircraft. Investigation revealed...

  18. Crystal structure of Au25(SePh)18 nanoclusters and insights into their electronic, optical and catalytic properties

    NASA Astrophysics Data System (ADS)

    Song, Yongbo; Zhong, Juan; Yang, Sha; Wang, Shuxin; Cao, Tiantian; Zhang, Jun; Li, Peng; Hu, Daqiao; Pei, Yong; Zhu, Manzhou

    2014-10-01

    The crystal structure of selenolate-capped Au25(SePh)18- nanoclusters has been unambiguously determined for the first time, and provides a solid basis for a deeper understanding of the structure-property relationships. The selenolate-capped Au25 cluster shows noticeable differences from the previously reported Au25(SCH2CH2Ph)18- counterpart, albeit both share the icosahedral Au13 core and semi-ring Au2(SeR)3 or Au2(SR)3 motifs. Distinct differences in the electronic structure and optical, catalytic and electrochemical properties are revealed by the coupling experiments with density functional theory (TD-DFT) calculations. Overall, the successful determination of the Au25(SePh)18- structure removes any ambiguity about its structure, and comparison with the thiolated Au25 counterpart helps us to further understand how the ligands affect the properties of the nanocluster.The crystal structure of selenolate-capped Au25(SePh)18- nanoclusters has been unambiguously determined for the first time, and provides a solid basis for a deeper understanding of the structure-property relationships. The selenolate-capped Au25 cluster shows noticeable differences from the previously reported Au25(SCH2CH2Ph)18- counterpart, albeit both share the icosahedral Au13 core and semi-ring Au2(SeR)3 or Au2(SR)3 motifs. Distinct differences in the electronic structure and optical, catalytic and electrochemical properties are revealed by the coupling experiments with density functional theory (TD-DFT) calculations. Overall, the successful determination of the Au25(SePh)18- structure removes any ambiguity about its structure, and comparison with the thiolated Au25 counterpart helps us to further understand how the ligands affect the properties of the nanocluster. Electronic supplementary information (ESI) available. See DOI: 10.1039/c4nr04631e

  19. Do we treat our patients or rather periodontal microbes with adjunctive antibiotics in periodontal therapy? A 16S rDNA microbial community analysis.

    PubMed

    Hagenfeld, Daniel; Koch, Raphael; Jünemann, Sebastian; Prior, Karola; Harks, Inga; Eickholz, Peter; Hoffmann, Thomas; Kim, Ti-Sun; Kocher, Thomas; Meyle, Jörg; Kaner, Doğan; Schlagenhauf, Ulrich; Ehmke, Benjamin; Harmsen, Dag

    2018-01-01

    Empiric antibiotics are often used in combination with mechanical debridement to treat patients suffering from periodontitis and to eliminate disease-associated pathogens. Until now, only a few next generation sequencing 16S rDNA amplicon based publications with rather small sample sizes studied the effect of those interventions on the subgingival microbiome. Therefore, we studied subgingival samples of 89 patients with chronic periodontitis (solely non-smokers) before and two months after therapy. Forty-seven patients received mechanical periodontal therapy only, whereas 42 patients additionally received oral administered amoxicillin plus metronidazole (500 and 400 mg, respectively; 3x/day for 7 days). Samples were sequenced with Illumina MiSeq 300 base pairs paired end technology (V3 and V4 hypervariable regions of the 16S rDNA). Inter-group differences before and after therapy of clinical variables (percentage of sites with pocket depth ≥ 5mm, percentage of sites with bleeding on probing) and microbiome variables (diversity, richness, evenness, and dissimilarity) were calculated, a principal coordinate analysis (PCoA) was conducted, and differential abundance of agglomerated ribosomal sequence variants (aRSVs) classified on genus level was calculated using a negative binomial regression model. We found statistically noticeable decreased richness, and increased dissimilarity in the antibiotic, but not in the placebo group after therapy. The PCoA revealed a clear compositional separation of microbiomes after therapy in the antibiotic group, which could not be seen in the group receiving mechanical therapy only. This difference was even more pronounced on aRSV level. Here, adjunctive antibiotics were able to induce a microbiome shift by statistically noticeably reducing aRSVs belonging to genera containing disease-associated species, e.g., Porphyromonas, Tannerella, Treponema, and Aggregatibacter, and by noticeably increasing genera containing health-associated species. Mechanical therapy alone did not statistically noticeably affect any disease-associated taxa. Despite the difference in microbiome modulation both therapies improved the tested clinical parameters after two months. These results cast doubt on the relevance of the elimination and/or reduction of disease-associated taxa as a main goal of periodontal therapy.

  20. The Noticing of Physical Education Teachers: A Comparison of Groups with Different Expertise

    ERIC Educational Resources Information Center

    Reuker, Sabine

    2017-01-01

    Background: Teachers' important diagnostic abilities include noticing and interpreting students' behaviors and learning processes. By focusing on noticing, I refer to the theoretical framework of professional vision. Professional vision includes the ability to notice what is occurring in complex classroom situations (selective attention) and the…

  1. Consumer purchasing patterns in response to calorie labeling legislation in New York City

    PubMed Central

    2011-01-01

    Background Obesity is a major public health threat and policies aimed at curbing this epidemic are emerging. National calorie labeling legislation is forthcoming and requires rigorous evaluation to examine its impact on consumers. The purpose of this study was to examine whether point-of-purchase calorie labels in New York City (NYC) chain restaurants affected food purchasing patterns in a sample of lower income adults in NYC and Newark, NJ. Methods This study utilized a difference-in-difference design to survey 1,170 adult patrons of four popular chain restaurants in NYC and Newark, NJ (which did not introduce labeling) before and after calorie labeling was implemented in NYC. Receipt data were collected and analyzed to examine food and beverage purchases and frequency of fast food consumption. Descriptive statistics were generated, and linear and logistic regression, difference-in-difference analysis, and predicted probabilities were used to analyze the data. Results A difference-in-difference analysis revealed no significant favorable differences and some unfavorable differences in food purchasing patterns and frequency of fast food consumption between adult patrons of fast food restaurants in NYC and Newark, NJ. Adults in NYC who reported noticing and using the calorie labels consumed fast food less frequently compared to adults who did not notice the labels (4.9 vs. 6.6 meals per week, p <0.05). Conclusion While no favorable differences in purchasing as a result of labeling were noted, self-reported use of calorie labels was associated with some favorable behavioral patterns in a subset of adults in NYC. However, overall impact of the legislation may be limited. More research is needed to understand the most effective way to deliver calorie information to consumers. PMID:21619632

  2. Consumer purchasing patterns in response to calorie labeling legislation in New York City.

    PubMed

    Vadiveloo, Maya K; Dixon, L Beth; Elbel, Brian

    2011-05-27

    Obesity is a major public health threat and policies aimed at curbing this epidemic are emerging. National calorie labeling legislation is forthcoming and requires rigorous evaluation to examine its impact on consumers. The purpose of this study was to examine whether point-of-purchase calorie labels in New York City (NYC) chain restaurants affected food purchasing patterns in a sample of lower income adults in NYC and Newark, NJ. This study utilized a difference-in-difference design to survey 1,170 adult patrons of four popular chain restaurants in NYC and Newark, NJ (which did not introduce labeling) before and after calorie labeling was implemented in NYC. Receipt data were collected and analyzed to examine food and beverage purchases and frequency of fast food consumption. Descriptive statistics were generated, and linear and logistic regression, difference-in-difference analysis, and predicted probabilities were used to analyze the data. A difference-in-difference analysis revealed no significant favorable differences and some unfavorable differences in food purchasing patterns and frequency of fast food consumption between adult patrons of fast food restaurants in NYC and Newark, NJ. Adults in NYC who reported noticing and using the calorie labels consumed fast food less frequently compared to adults who did not notice the labels (4.9 vs. 6.6 meals per week, p <0.05). While no favorable differences in purchasing as a result of labeling were noted, self-reported use of calorie labels was associated with some favorable behavioral patterns in a subset of adults in NYC. However, overall impact of the legislation may be limited. More research is needed to understand the most effective way to deliver calorie information to consumers.

  3. Intraspecies Genomic Diversity and Natural Population Structure of the Meat-Borne Lactic Acid Bacterium Lactobacillus sakei▿ †

    PubMed Central

    Chaillou, Stéphane; Daty, Marie; Baraige, Fabienne; Dudez, Anne-Marie; Anglade, Patricia; Jones, Rhys; Alpert, Carl-Alfred; Champomier-Vergès, Marie-Christine; Zagorec, Monique

    2009-01-01

    Lactobacillus sakei is a food-borne bacterium naturally found in meat and fish products. A study was performed to examine the intraspecies diversity among 73 isolates sourced from laboratory collections in several different countries. Pulsed-field gel electrophoresis analysis demonstrated a 25% variation in genome size between isolates, ranging from 1,815 kb to 2,310 kb. The relatedness between isolates was then determined using a PCR-based method that detects the possession of 60 chromosomal genes belonging to the flexible gene pool. Ten different strain clusters were identified that had noticeable differences in their average genome size reflecting the natural population structure. The results show that many different genotypes may be isolated from similar types of meat products, suggesting a complex ecological habitat in which intraspecies diversity may be required for successful adaptation. Finally, proteomic analysis revealed a slight difference between the migration patterns of highly abundant GapA isoforms of the two prevailing L. sakei subspecies (sakei and carnosus). This analysis was used to affiliate the genotypic clusters with the corresponding subspecies. These findings reveal for the first time the extent of intraspecies genomic diversity in L. sakei. Consequently, identification of molecular subtypes may in the future prove valuable for a better understanding of microbial ecosystems in food products. PMID:19114527

  4. Intraspecies genomic diversity and natural population structure of the meat-borne lactic acid bacterium Lactobacillus sakei.

    PubMed

    Chaillou, Stéphane; Daty, Marie; Baraige, Fabienne; Dudez, Anne-Marie; Anglade, Patricia; Jones, Rhys; Alpert, Carl-Alfred; Champomier-Vergès, Marie-Christine; Zagorec, Monique

    2009-02-01

    Lactobacillus sakei is a food-borne bacterium naturally found in meat and fish products. A study was performed to examine the intraspecies diversity among 73 isolates sourced from laboratory collections in several different countries. Pulsed-field gel electrophoresis analysis demonstrated a 25% variation in genome size between isolates, ranging from 1,815 kb to 2,310 kb. The relatedness between isolates was then determined using a PCR-based method that detects the possession of 60 chromosomal genes belonging to the flexible gene pool. Ten different strain clusters were identified that had noticeable differences in their average genome size reflecting the natural population structure. The results show that many different genotypes may be isolated from similar types of meat products, suggesting a complex ecological habitat in which intraspecies diversity may be required for successful adaptation. Finally, proteomic analysis revealed a slight difference between the migration patterns of highly abundant GapA isoforms of the two prevailing L. sakei subspecies (sakei and carnosus). This analysis was used to affiliate the genotypic clusters with the corresponding subspecies. These findings reveal for the first time the extent of intraspecies genomic diversity in L. sakei. Consequently, identification of molecular subtypes may in the future prove valuable for a better understanding of microbial ecosystems in food products.

  5. Working memory and inattentional blindness.

    PubMed

    Bredemeier, Keith; Simons, Daniel J

    2012-04-01

    Individual differences in working memory predict many aspects of cognitive performance, especially for tasks that demand focused attention. One negative consequence of focused attention is inattentional blindness, the failure to notice unexpected objects when attention is engaged elsewhere. Yet, the relationship between individual differences in working memory and inattentional blindness is unclear; some studies have found that higher working memory capacity is associated with greater noticing, but others have found no direct association. Given the theoretical and practical significance of such individual differences, more definitive tests are needed. In two studies with large samples, we tested the relationship between multiple working memory measures and inattentional blindness. Individual differences in working memory predicted the ability to perform an attention-demanding tracking task, but did not predict the likelihood of noticing an unexpected object present during the task. We discuss the reasons why we might not expect such individual differences in noticing and why other studies may have found them.

  6. 78 FR 55772 - Culturally Significant Object Imported for Exhibition Determinations: “Beauty Revealed: Images of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ..., 1965 (79 Stat. 985; 22 U.S.C. 2459), Executive Order 12047 of March 27, 1978, the Foreign Affairs Reform and Restructuring Act of 1998 (112 Stat. 2681, et seq.; 22 U.S.C. 6501 note, et seq.), Delegation... Determinations: ``Beauty Revealed: Images of Women in Qing Dynasty Chinese Painting'' SUMMARY: Notice is hereby...

  7. 29 CFR 4281.32 - Notices of benefit reductions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the notice at participants' work sites or publishing the notice in a union newsletter or in a... and the three-digit Plan Number (PN) assigned by the plan sponsor to the plan, and, if different, the EIN or PN last filed with the PBGC. If no EIN or PN has been assigned, the notice shall so state. (4...

  8. 29 CFR 4281.32 - Notices of benefit reductions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the notice at participants' work sites or publishing the notice in a union newsletter or in a... and the three-digit Plan Number (PN) assigned by the plan sponsor to the plan, and, if different, the EIN or PN last filed with the PBGC. If no EIN or PN has been assigned, the notice shall so state. (4...

  9. Effect of virgin coconut oil on properties of surimi gel.

    PubMed

    Gani, Asir; Benjakul, Soottawat; Nuthong, Pornpot

    2018-02-01

    Effects of virgin coconut oil (VCO) at various levels (0-25%) on the properties of croaker surimi gels were studied. As the levels of VCO increased up to 15%, breaking force continuously decreased. No differences in breaking force, deformation and fracture constant were noticeable when VCO of 15-25% was incorporated. Based on texture profile analysis, hardness and chewiness decreased as the level of added VCO increased up to 10%, while no marked changes were observed with the addition of 10-25% VCO. Addition of VCO had no profound impact on springiness, cohesiveness and resilience. No remarkable change in protein pattern among all surimi gel samples was noticed, regardless of VCO levels. Lower elastic (G') as well as loss moduli (G″) of surimi paste were observed when VCO was added, compared to the control. Nevertheless, there was no marked difference in the moduli among samples containing VCO at all levels. Whiteness of surimi gel increased, whereas expressible moisture content decreased as VCO levels increased. Microstructure study revealed that VCO droplets were distributed uniformly in gel network. Overall likeness of surimi gel was also increased for gel added with VCO. Therefore, VCO addition directly affected textural properties and improved the whiteness as well as sensory property of surimi gel.

  10. Corrosion Behavior of Detonation Gun Sprayed Fe-Al Type Intermetallic Coating

    PubMed Central

    Senderowski, Cezary; Chodala, Michal; Bojar, Zbigniew

    2015-01-01

    The detonation gun sprayed Fe-Al type coatings as an alternative for austenitic valve steel, were investigated using two different methods of testing corrosion resistance. High temperature, 10-hour isothermal oxidation experiments at 550, 750, 950 and 1100 °C show differences in the oxidation behavior of Fe-Al type coatings under air atmosphere. The oxide layer ensures satisfying oxidation resistance, even at 950 and 1100 °C. Hematite, α-Al2O3 and metastable alumina phases were noticed on the coatings top surface, which preserves its initial thickness providing protection to the underlying substrate. In general, only negligible changes of the phase composition of the coatings were noticed with simultaneous strengthening controlled in the micro-hardness measurements, even after 10-hours of heating at 1100 °C. On the other hand, the electrochemical corrosion tests, which were carried out in 200 ppm Cl− (NaCl) and pH ~4 (H2SO4) solution to simulate the acid-rain environment, reveal higher values of the breakdown potential for D-gun sprayed Fe-Al type coatings than the ones for the bulk Fe-Al type alloy and Cr21Mn9Ni4 austenitic valve steel. This enables these materials to be used in structural and multifunctional applications in aggressive environments, including acidic ones. PMID:28787991

  11. Biochemical changes in some deciduous tree species around Talcher thermal power station, Odisha, India.

    PubMed

    Nayak, Rekha; Biswal, Debasis; Sett, Rupnarayan

    2013-05-01

    The present study was conducted to evaluate biochemical traits in leaves to assess the air pollution impact on plants caused by thermal power plant emissions. Ten species of deciduous trees were selected from study sites in different seasons. pH, chlorophyll, phenols, total soluble sugar content and proline content in fresh leaf was analyzed. The leaf wash pH content reveals moderately acidic (4.5-5.0) to highly acidic (3.5-4.5) range. Significant differences (p < 0.01) were observed in chlorophyll content according to the seasons and sites. Maximum reduction in chlorophyll was noticed at 2.5 km and 5.0 km west from the power plant. Greater reduction in chloropohyll 'b' than chlorophyll 'a' was noticed. An increase in total soluble sugars and phenols was observed at sites closer to thermal power plant in comparison to control. Highest concentration of total phenols was found in summer season in Dalbergia sissoo (1.52%), Butea monosperma (1.12%), Mangifera indica (1.2%), Tectona grandis (1.26%) and Acacia leucophloea (1.16%) at 2.5 km north from the source. Highest concentration of soluble sugar was found in Dalbergia sissoo (7.75%) during winter season. There was about 10-20 fold increase in proline content of leaves in comparison to the control.

  12. How do titanium and Ti6Al4V corrode in fluoridated medium as found in the oral cavity? An in vitro study.

    PubMed

    Souza, Júlio C M; Barbosa, Sandra L; Ariza, Edith A; Henriques, Mariana; Teughels, Wim; Ponthiaux, Pierre; Celis, Jean-Pierre; Rocha, Luis A

    2015-02-01

    The purpose of this work was to evaluate the corrosion of commercially pure (CP) titanium and Ti6Al4V in vitro at different F(-) concentrations regularly found in the oral cavity by using different electrochemical tests and surface analysis techniques. electrochemical impedance spectroscopy (EIS), open circuit potential (OCP) and potentiodynamic polarization tests were associated to advanced characterization techniques such as SEM, EDS, AFM, ICP-MS and XPS. OCP tests revealed a higher reactivity of both CP titanium and Ti6Al4V at 12,300 ppm F(-) concentration than that recorded at 227 ppm F(-). Also, a significant decrease of the corrosion resistance of both materials was noticed by EIS in fluoride solutions. Material loss caused by corrosion was noticed on titanium surfaces by SEM and AFM in the presence of high F(-) concentration. CP titanium degraded by pitting corrosion while Ti6Al4V suffered from general corrosion showing micro-cracks on surface. Furthermore, a high release of metallic ions from the test samples after immersion at high F(-) concentrations was detected by ICP-MS, that can be potentially toxic to oral tissues. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. 77 FR 38661 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    .... Customer Service Dept., Billing Integrity, Aerotex, Medix, and Accountemps. 81,605 RapcoHorizon Company..., PA. Renumeration Accounting Department, Kelly Services. The investigation revealed that the criteria...

  14. 75 FR 65513 - General Motors Company, Pontiac Company, Pontiac, MI; Notice of Affirmative Determination...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ... Automobile, Aerospace, and Agricultural Implement Workers of America (UAW) requested administrative... competitive with the automobiles produced by the workers. The investigation also revealed that the workers did...

  15. 77 FR 36012 - Notice of Record of Decision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-15

    ... the potential impacts on the human and natural environment as a result of marine seismic surveys... that reveal the structure and stratigraphy of the crust and/or overlying sediment below the world's...

  16. 29 CFR 4281.44 - Contents of notices of insolvency and annual updates.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Contents of notices of insolvency and annual updates. 4281... insolvency and annual updates. (a) Notice of insolvency to the PBGC. A notice of insolvency required under..., and, if different, the EIN or PN last filed with the PBGC. If no EIN or PN has been assigned, the...

  17. 29 CFR 4281.44 - Contents of notices of insolvency and annual updates.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Contents of notices of insolvency and annual updates. 4281... insolvency and annual updates. (a) Notice of insolvency to the PBGC. A notice of insolvency required under..., and, if different, the EIN or PN last filed with the PBGC. If no EIN or PN has been assigned, the...

  18. Significance of immune response to Mycobacterium tuberculosis culture filtrate protein antigens in cerebrospinal fluid of tuberculous meningitis patients: A search for diagnostic marker.

    PubMed

    Giribhattanavar, Prashant; Kumar, Kavitha; Raajasekar, Siddarth; Chandrashekar, Nagarathna; Patil, Shripad A

    2017-01-01

    Mycobacterium tuberculosis (H37Ra) culture filtrate proteins (CFP) are explored as a diagnostic marker for tuberculous meningitis (TBM). Cerebrospinal fluid (CSF) samples from patients were categorized as confirmed (n = 47), suspected (n = 20), and non-TBM (n = 25) cases. Immune response by Western blot revealed TBM CSF samples are having heterogeneous response to CFP. CFP ELISA was 92% sensitive and 38.30% specific. ODs of confirmed TBM and non-TBM cases were significantly different (P < 0.0001) and also the suspected TBM and non-TBM cases (P = 0.0001). No significant difference noticed in TBM and suspected TBM (P = 0.90). Thus, CFP can be a better biomarker for the diagnosis of TBM.

  19. Synthesis of Silver Polymer Nanocomposites and Their Antibacterial Activity

    NASA Astrophysics Data System (ADS)

    Gavade, Chaitali; Shah, Sunil; Singh, N. L.

    2011-07-01

    PVA (Polyvinyl Alcohol) silver nanocomposites of different sizes were prepared by chemical reduction method. Silver nitrate was taken as the metal precursor and amine hydrazine as a reducing agent. The formation of the silver nanoparticles was noticed using UV- visible absorption spectroscopy. The UV-visible spectroscopy revealed the formation of silver nanoparticles by exhibiting the surface plasmon resonance. The bactericidal activity due to silver release from the surface was determined by the modification of conventional diffusion method. Salmonella typhimurium, Serratia sps and Shigella sps were used as test bacteria which are gram-negative type bacteria. Effect of the different sizes of silver nano particles on antibacterial efficiency was discussed. Zones of inhibition were measured after 24 hours of incubation at 37 °C which gave 20 mm radius for high concentration of silver nanoparticles.

  20. In-vitro biocompatibility and corrosion resistance of electrochemically assembled PPy/TNTA hybrid material for biomedical applications

    NASA Astrophysics Data System (ADS)

    Simi, V. S.; Satish, Aishwarya; Korrapati, Purna Sai; Rajendran, N.

    2018-07-01

    Nanostructured hybrid materials composed of inorganic and organic constituents of different chemistry and functionality have attracted wide range of biomedical applications. The uniform electrodeposition of polypyrrole into titania nanotube arrays was achieved by normal pulse voltammetry technique in lithium perchlorate electrolyte by varying the pulse period. The electrochemically assembled polypyrrole/titania nanotube arrays (PPy/TNTA) surface was characterized by structural characterizations including attenuated total reflectance -fourier transform infrared spectroscopy, Raman and X-ray photoelectron spectroscopy analysis. Morphological study carried out by high resolution scanning electron microscopy demonstrates the influence of varying pulse period in achieving the controlled deposition of polypyrrole into the nanotube frame work. Cyclic voltammetry study reveals the electroactive nature of the hybrid material. The contact angle measurements and In-vitro immersion studies in stimulated body fluid hanks' solution were carried out to evaluate the wettability and apatite forming ability of the developed hybrid material. The deposition of polypyrrole enhanced the corrosion resistance of TNTA as evidenced from the lower icorr value observed for PPy/TNTA. The corrosion protection behavior of the hybrid material revealed from the electrochemical impedance spectroscopic studies was clearly noticed from the increase in impedance and maximum phase angle values. Further In-vitro cell culture studies were carried out using MG63 osteoblast cells to evaluate the biocompatibility of the hybrid material. Noticeable improvement in corrosion protection and biocompatibility performance suggest the possible application of PPy/TNTA hybrid material for biomedical applications.

  1. 76 FR 79225 - 2002 Reopened-Previously Denied Determinations; Notice of Negative Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ... reconsideration investigation revealed that the following workers groups have not met the certification criteria... Department's Web site at tradeact/taa/taa-- search--form.cfm under the searchable listing of determinations...

  2. 76 FR 81990 - 2002 Reopened-Previously Denied Determinations; Notice of Negative Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... reconsideration investigation revealed that the following workers groups have not met the certification criteria... Department's Web site at tradeact/taa/taa-- search--form.cfm under the searchable listing of determinations...

  3. 77 FR 3506 - 2002 Reopened-Previously Denied Determinations; Notice of Negative Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-24

    ... reconsideration investigation revealed that the following workers groups have not met the certification criteria... Department's Web site at tradeact/taa/taa-- search--form.cfm under the searchable listing of determinations...

  4. 76 FR 77558 - 2002 Reopened-Previously Denied Determinations; Notice of Negative Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... reconsideration investigation revealed that the following workers groups have not met the certification criteria... at tradeact/taa/taa--search--form.cfm under the searchable listing of determinations or by calling...

  5. 78 FR 4459 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... investigation resulting in-- (A) An affirmative determination of serious injury or threat thereof under section..., MN...... Inc., General Mills, Inc., Manpower, Certes, Salo, etc. The investigation revealed that the...

  6. Self-organization in a bimotility mixture of model microswimmers

    NASA Astrophysics Data System (ADS)

    Agrawal, Adyant; Babu, Sujin B.

    2018-02-01

    We study the cooperation and segregation dynamics in a bimotility mixture of microorganisms which swim at low Reynolds numbers via periodic deformations along the body. We employ a multiparticle collision dynamics method to simulate a two component mixture of artificial swimmers, termed as Taylor lines, which differ from each other only in the propulsion speed. The analysis reveals that a contribution of slower swimmers towards clustering, on average, is much larger as compared to the faster ones. We notice distinctive self-organizing dynamics, depending on the percentage difference in the speed of the two kinds. If this difference is large, the faster ones fragment the clusters of the slower ones in order to reach the boundary and form segregated clusters. Contrarily, when it is small, both kinds mix together at first, the faster ones usually leading the cluster and then gradually the slower ones slide out thereby also leading to segregation.

  7. Work-Family Conflict Among Employees and the Self-Employed Across Europe.

    PubMed

    Annink, Anne; den Dulk, Laura; Steijn, Bram

    This article examines the level of work-family conflict of self-employed persons, a changing but neglected group in work-life research, compared to employees in Europe. Differences between the two groups are explained by looking at job demands and resources. The inclusion of work-family state support makes it possible to examine differences between countries. Multilevel analysis has been applied to data from the European Social Survey (ESS 2010). The results show that job demands and resources operate differently for employees and the self-employed. The relationship between employment type and WFC is mediated mainly by job demands such as working hours, working at short notice, job insecurity and supervisory work. The results also reveal variation across countries that cannot be explained by state support, signalling the need for a more complete understanding of WFC from a cross-national perspective.

  8. 77 FR 5577 - 2002 Reopened-Previously Denied Determinations; Notice of Revised Denied Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-03

    ... reconsideration investigation revealed that the following workers groups have met the certification criteria under... available on the Department's Web site at tradeact/taa/taa-- search--form.cfm under the searchable listing...

  9. 77 FR 5577 - 2002 Reopened-Previously Denied Determinations; Notice of Negative Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-03

    ... reconsideration investigation revealed that the following workers groups have not met the certification criteria... available on the Department's Web site at tradeact/taa/taa-- search--form.cfm under the searchable listing...

  10. 77 FR 12086 - 2002 Reopened-Previously Denied Determinations; Notice of Revised Denied Determinations On...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ... reconsideration investigation revealed that the following workers groups have met the certification criteria under... at tradeact/taa/taa--search--form.cfm under the searchable listing of determinations or by calling...

  11. 76 FR 81991 - 2002 Reopened-Previously Denied Determinations; Notice of Revised Denied Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... reconsideration investigation revealed that the following workers groups have met the certification criteria under...-- search--form.cfm under the searchable listing of determinations or by calling the Office of Trade...

  12. 77 FR 13356 - 2002 Reopened-Previously Denied Determinations; Notice of Revised Denied Determinations On...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-06

    ... reconsideration investigation revealed that the following workers groups have met the certification criteria under... site at tradeact/taa/taa--search--form.cfm under the searchable listing of determinations or by calling...

  13. 76 FR 81991 - 2002 Reopened-Previously Denied Determinations; Notice of Revised Denied Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... reconsideration investigation revealed that the following workers groups have met the certification criteria under... site at tradeact/taa/taa--search--form.cfm under the searchable listing of determinations or by calling...

  14. 77 FR 6592 - Notice of Negative Determinations on Reconsideration Under the Trade Adjustment Assistance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ... reconsideration investigation revealed that the following workers groups have not met the certification criteria... are available on the Department's Web site at tradeact/taa/taa--search--form.cfm under the searchable...

  15. 77 FR 13356 - 2002 Reopened-Previously Denied Determinations; Notice of Negative Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-06

    ... reconsideration investigation revealed that the following workers groups have not met the certification criteria.../taa/taa-- search--form.cfm under the searchable listing of determinations or by calling the Office of...

  16. 77 FR 6592 - 2002 Reopened-Previously Denied Determinations; Notice of Revised Denied Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ... reconsideration investigation revealed that the following workers groups have met the certification criteria under...-- search--form.cfm under the searchable listing of determinations or by calling the Office of Trade...

  17. 77 FR 9974 - 2002 Reopened-Previously Denied Determinations; Notice of Negative Determinations On...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-21

    ... reconsideration investigation revealed that the following workers groups have not met the certification criteria.../taa--search--form.cfm under the searchable listing of determinations or by calling the Office of Trade...

  18. 76 FR 77558 - 2002 Reopened-Previously Denied Determinations; Notice of Revised Denied Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... reconsideration investigation revealed that the following workers groups have met the certification criteria under... are available on the Department's Web site at tradeact/taa/taa--search--form.cfm under the searchable...

  19. 76 FR 10403 - General Motors Company, Pontiac Assembly; Pontiac, MI; Notice of Negative Determination on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... automobiles produced by the workers. The investigation also revealed that the workers did not produce a... certification. In the request for reconsideration, the International Union of United Automobile, Aerospace, and...

  20. Request for Available Information on Chlorinated Paraffins Submitted as Pre-Manufacture Notices (PMNs)

    EPA Pesticide Factsheets

    EPA is requesting new available data on certain chlorinated paraffins in different industries and for different uses, to inform the risk assessments for chlorinated paraffins submitted as Toxic Substances Control Act (TSCA) Premanufacture Notices (PMNs).

  1. Educational differences in associations of noticing anti-tobacco information with smoking-related attitudes and quit intentions: findings from the International Tobacco Control Europe Surveys

    PubMed Central

    Springvloet, L.; Willemsen, M. C.; Mons, U.; van den Putte, B.; Kunst, A. E.; Guignard, R.; Hummel, K.; Allwright, S.; Siahpush, M.; de Vries, H.; Nagelhout, G. E.

    2015-01-01

    This study examined educational differences in associations of noticing anti-tobacco information with smoking-related attitudes and quit intentions among adult smokers. Longitudinal data (N = 7571) from two waves of six countries of the International Tobacco Control (ITC) Europe Surveys were included. Generalized estimating equation analyses and multiple linear and logistic regression analyses were conducted. Higher educated smokers noticed anti-tobacco information slightly more often than lower educated smokers (F(2) = 25.78, P < 0.001). Noticing anti-tobacco information was associated with more negative smoking-related attitudes (β = 0.05, P < 0.001) and more quit intentions (OR = 1.08, P < 0.001). Among smokers without a quit intention at baseline, a positive association was found for noticing anti-tobacco information at baseline with follow-up quit intention (OR = 1.14, P = 0.003). No other longitudinal associations were found. No educational differences were found in the association of noticing anti-tobacco information with smoking-related attitudes but associations with quit intentions were found only among low (OR = 1.12, P = 0.001) and high educated respondents (OR = 1.11, P < 0.001) and not among moderate educated respondents (OR = 1.02, P = 0.43). Noticing anti-tobacco information may positively influence quit intentions and possibly smoking-related attitudes. Lower educated smokers were as likely to be influenced by anti-tobacco information as higher educated smokers but noticed anti-tobacco information less often; increasing reach of anti-tobacco information may increase impact in this group. PMID:26324396

  2. Comparison of intrinsic dynamics of cytochrome p450 proteins using normal mode analysis

    PubMed Central

    Dorner, Mariah E; McMunn, Ryan D; Bartholow, Thomas G; Calhoon, Brecken E; Conlon, Michelle R; Dulli, Jessica M; Fehling, Samuel C; Fisher, Cody R; Hodgson, Shane W; Keenan, Shawn W; Kruger, Alyssa N; Mabin, Justin W; Mazula, Daniel L; Monte, Christopher A; Olthafer, Augustus; Sexton, Ashley E; Soderholm, Beatrice R; Strom, Alexander M; Hati, Sanchita

    2015-01-01

    Cytochrome P450 enzymes are hemeproteins that catalyze the monooxygenation of a wide-range of structurally diverse substrates of endogenous and exogenous origin. These heme monooxygenases receive electrons from NADH/NADPH via electron transfer proteins. The cytochrome P450 enzymes, which constitute a diverse superfamily of more than 8,700 proteins, share a common tertiary fold but < 25% sequence identity. Based on their electron transfer protein partner, cytochrome P450 proteins are classified into six broad classes. Traditional methods of pro are based on the canonical paradigm that attributes proteins' function to their three-dimensional structure, which is determined by their primary structure that is the amino acid sequence. It is increasingly recognized that protein dynamics play an important role in molecular recognition and catalytic activity. As the mobility of a protein is an intrinsic property that is encrypted in its primary structure, we examined if different classes of cytochrome P450 enzymes display any unique patterns of intrinsic mobility. Normal mode analysis was performed to characterize the intrinsic dynamics of five classes of cytochrome P450 proteins. The present study revealed that cytochrome P450 enzymes share a strong dynamic similarity (root mean squared inner product > 55% and Bhattacharyya coefficient > 80%), despite the low sequence identity (< 25%) and sequence similarity (< 50%) across the cytochrome P450 superfamily. Noticeable differences in Cα atom fluctuations of structural elements responsible for substrate binding were noticed. These differences in residue fluctuations might be crucial for substrate selectivity in these enzymes. PMID:26130403

  3. 77 FR 3506 - 2002 Reopened-Previously Denied Determinations; Notice of Revised Denied Determinations On...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-24

    ... reconsideration investigation revealed that the following workers groups have met the certification criteria under... available on the Department's Web site at tradeact/taa/taa--search--form.cfm under the searchable listing of...

  4. 76 FR 175 - Kennametal, Inc., Irwin, PA; Kennametal, Inc., Including On-Site Leased Workers of Spherion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-03

    ... Department's Notice of Determination was published in the Federal Register on April 23, 2010 (75 FR 21354... carbide performs and armor piercing products. Information obtained by the Department revealed that the...

  5. Angular distributions of the protons in the reaction. pi. /sup +/+Xe. -->. p+xxx at 2. 34 GeV/c as a background for the shock-wave effect

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Slowinski, B.; Strugalski, Z.

    1977-02-20

    Results are presented of an analysis of the angular distributions of protons with E/sub p/> or =30 MeV emitted with different numbers of secondary charged particles in ..pi../sup +/+Xe interactions at 2.34 GeV/c. The obtained distributions are compared with the analogous characteristics of the protons emitted in collisions of protons or ..cap alpha.. particles with heavy emulsion nuclei and with lead at 70 and 17 GeV/c. It is concluded that the investigated distributions reveal no irregularities capable of attesting to a noticable role of the shock-wave mechanism in the target nuclei.

  6. [Electroencephalography measures in motor skill learning and effects of bromazepam].

    PubMed

    Bastos, Victor Hugo; Machado, Dionis; Cunha, Marlo; Portella, Claudio Elidio; Cagy, Maurício; Furtado, Vernon; Piedade, Roberto; Ribeiro, Pedro

    2005-06-01

    Neuromodulators change brain's neural circuitry. Bromazepam is often been used in the pharmacological treatment of anxiety disorders. Few papers links this anxiolytic to motor tasks. The purpose of this study was to examine motor and electrophysiological changes produced by administration of bromazepam in differents doses (3 and 6 mg). The sample consisted of 39 healthy individuals, of both sexes, between 20 and 30 years of age. The control (placebo) and experimental (bromazepam 3mg and bromazepam 6 mg) groups were submitted to a typewriting task, in a randomized, double-blind design. The results did not reveal differences on score and time of the attention test. In the comportamental analysis was noticed blocks as main effect to behavioral variables (time and mistakes in the task). Electrophysiological data showed significants interactions to: laterally/condition/moment; laterally/condition; laterally/moment; condition/moment; condition/site.

  7. The Accuracy and Correction of Fuel Consumption from Controller Area Network Broadcast

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Lijuan; Gonder, Jeffrey D; Wood, Eric W

    Fuel consumption (FC) has always been an important factor in vehicle cost. With the advent of electronically controlled engines, the controller area network (CAN) broadcasts information about engine and vehicle performance, including fuel use. However, the accuracy of the FC estimates is uncertain. In this study, the researchers first compared CAN-broadcasted FC against physically measured fuel use for three different types of trucks, which revealed the inaccuracies of CAN-broadcast fueling estimates. To match precise gravimetric fuel-scale measurements, polynomial models were developed to correct the CAN-broadcasted FC. Lastly, the robustness testing of the correction models was performed. The training cycles inmore » this section included a variety of drive characteristics, such as high speed, acceleration, idling, and deceleration. The mean relative differences were reduced noticeably.« less

  8. Educational differences in associations of noticing anti-tobacco information with smoking-related attitudes and quit intentions: findings from the International Tobacco Control Europe Surveys.

    PubMed

    Springvloet, L; Willemsen, M C; Mons, U; van den Putte, B; Kunst, A E; Guignard, R; Hummel, K; Allwright, S; Siahpush, M; de Vries, H; Nagelhout, G E

    2015-10-01

    This study examined educational differences in associations of noticing anti-tobacco information with smoking-related attitudes and quit intentions among adult smokers. Longitudinal data (N = 7571) from two waves of six countries of the International Tobacco Control (ITC) Europe Surveys were included. Generalized estimating equation analyses and multiple linear and logistic regression analyses were conducted. Higher educated smokers noticed anti-tobacco information slightly more often than lower educated smokers (F(2) = 25.78, P < 0.001). Noticing anti-tobacco information was associated with more negative smoking-related attitudes (β = 0.05, P < 0.001) and more quit intentions (OR = 1.08, P < 0.001). Among smokers without a quit intention at baseline, a positive association was found for noticing anti-tobacco information at baseline with follow-up quit intention (OR = 1.14, P = 0.003). No other longitudinal associations were found. No educational differences were found in the association of noticing anti-tobacco information with smoking-related attitudes but associations with quit intentions were found only among low (OR = 1.12, P = 0.001) and high educated respondents (OR = 1.11, P < 0.001) and not among moderate educated respondents (OR = 1.02, P = 0.43). Noticing anti-tobacco information may positively influence quit intentions and possibly smoking-related attitudes. Lower educated smokers were as likely to be influenced by anti-tobacco information as higher educated smokers but noticed anti-tobacco information less often; increasing reach of anti-tobacco information may increase impact in this group. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  9. An Observation on the Spontaneous Noticing of Prospective Memory Event-Based Cues

    ERIC Educational Resources Information Center

    Knight, Justin B.; Meeks, J. Thadeus; Marsh, Richard L.; Cook, Gabriel I.; Brewer, Gene A.; Hicks, Jason L.

    2011-01-01

    In event-based prospective memory, current theories make differing predictions as to whether intention-related material can be spontaneously noticed (i.e., noticed without relying on preparatory attentional processes). In 2 experiments, participants formed an intention that was contextually associated to the final phase of the experiment, and…

  10. Phonon Raman spectra of colloidal CdTe nanocrystals: effect of size, non-stoichiometry and ligand exchange

    PubMed Central

    2011-01-01

    Resonant Raman study reveals the noticeable effect of the ligand exchange on the nanocrystal (NC) surface onto the phonon spectra of colloidal CdTe NC of different size and composition. The oleic acid ligand exchange for pyridine ones was found to change noticeably the position and width of the longitudinal optical (LO) phonon mode, as well as its intensity ratio to overtones. The broad shoulder above the LO peak frequency was enhanced and sharpened after pyridine treatment, as well as with decreasing NC size. The low-frequency mode around 100 cm-1 which is commonly related with the disorder-activated acoustical phonons appears in smaller NCs but is not enhanced after pyridine treatment. Surprisingly, the feature at low-frequency shoulder of the LO peak, commonly assigned to the surface optical phonon mode, was not sensitive to ligand exchange and concomitant close packing of the NCs. An increased structural disorder on the NC surface, strain and modified electron-phonon coupling is discussed as the possible reason of the observed changes in the phonon spectrum of ligand-exchanged CdTe NCs. PACS: 63.20.-e, 78.30.-j, 78.67.-n, 78.67.Bf PMID:21711581

  11. Compositional dependence of defect mobility and damage buildup in Al xGa 1- xAs

    NASA Astrophysics Data System (ADS)

    Stonert, A.; Turos, A.; Nowicki, L.; Breeger, B.; Wendler, E.; Wesch, W.

    2001-04-01

    Defect transformations at low temperatures in ion implanted Al xGa 1- xAs (0⩽ x⩽1) ternary compounds were studied. Experiments consisted of ion implantation with 150 keV N or 200 keV Ar ions with different doses at temperatures between 18 and 77 K, and in situ RBS/channeling measurements at selected temperatures. An important recovery stage attributed to the defect mobility in the Ga(Al) sublattice was revealed near 280 K. For x>0.5 this stage was largely suppressed. Instead, a continuous damage recovery at low temperatures was observed. It was noticed that defect recombination can also be produced upon prolonged storage at the implantation temperature. For AlAs ( x=1) the 280 K stage disappeared completely and only a small defect recovery at low temperatures was noticed. Upon N- or Ar-ion bombardment, after an incubation period, a sharp crystalline-to-amorphous transition appeared. The amorphization dose increases with increasing x and is a factor of 10 higher for x=0.96 than that for x=0. A further increase of the dose by a factor of 15 was required to amorphize AlAs ( x=1).

  12. Intraoperative near-infrared autofluorescence imaging of parathyroid glands.

    PubMed

    Ladurner, Roland; Sommerey, Sandra; Arabi, Nora Al; Hallfeldt, Klaus K J; Stepp, Herbert; Gallwas, Julia K S

    2017-08-01

    To identify parathyroid glands intraoperatively by exposing their autofluorescence using near-infrared light. Fluorescence imaging was carried out during minimally invasive and open parathyroid and thyroid surgery. After identification, the parathyroid glands as well as the surrounding tissue were exposed to near-infrared (NIR) light with a wavelength of 690-770 nm using a modified Karl Storz near-infrared/indocyanine green (NIR/ICG) endoscopic system. Parathyroid tissue was expected to show near-infrared autofluorescence, captured in the blue channel of the camera. Whenever possible the visual identification of parathyroid tissue was confirmed histologically. In preliminary investigations, using the original NIR/ICG endoscopic system we noticed considerable interference of light in the blue channel overlying the autofluorescence. Therefore, we modified the light source by interposing additional filters. In a second series, we investigated 35 parathyroid glands from 25 patients. Twenty-seven glands were identified correctly based on NIR autofluorescence. Regarding the extent of autofluorescence, there were no noticeable differences between parathyroid adenomas, hyperplasia and normal parathyroid glands. In contrast, thyroid tissue, lymph nodes and adipose tissue revealed no substantial autofluorescence. Parathyroid tissue is characterized by showing autofluorescence in the near-infrared spectrum. This effect can be used to distinguish parathyroid glands from other cervical tissue entities.

  13. Characterization and identification of novel antidiabetic and anti-obesity peptides from camel milk protein hydrolysates.

    PubMed

    Mudgil, Priti; Kamal, Hina; Yuen, Gan Chee; Maqsood, Sajid

    2018-09-01

    In-vitro inhibitory properties of peptides released from camel milk proteins against dipeptidyl peptidase-IV (DPP-IV), porcine pancreatic α-amylase (PPA), and porcine pancreatic lipase (PPL) were studied. Results revealed that upon hydrolysis by different enzymes, camel milk proteins displayed dramatic increase in inhibition of DPP-IV and PPL, but slight improvement in PPA inhibition was noticed. Peptide sequencing revealed a total of 20 and 3 peptides for A9 and B9 hydrolysates respectively, obtained the score of 0.8 or more on peptide ranker and were categorized as potential DPP-IV inhibitory peptides. KDLWDDFKGL in A9 and MPSKPPLL in B9 were identified as most potent PPA inhibitory peptide. For PPL inhibition only 7 and 2 peptides qualified as PPL inhibitory peptides from hydrolysates A9 and B9, respectively. The present study report for the first time PPA and PPL inhibitory and only second for DPP-IV inhibitory potential of protein hydrolysates from camel milk. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. In-vitro bioactivity, biocompatibility and dissolution studies of diopside prepared from biowaste by using sol-gel combustion method.

    PubMed

    Choudhary, Rajan; Vecstaudza, Jana; Krishnamurithy, G; Raghavendran, Hanumantha Rao Balaji; Murali, Malliga Raman; Kamarul, Tunku; Swamiappan, Sasikumar; Locs, Janis

    2016-11-01

    Diopside was synthesized from biowaste (Eggshell) by sol-gel combustion method at low calcination temperature and the influence of two different fuels (urea, l-alanine) on the phase formation temperature, physical and biological properties of the resultant diopside was studied. The synthesized materials were characterized by heating microscopy, FTIR, XRD, BET, SEM and EDAX techniques. BET analysis reveals particles were of submicron size with porosity in the nanometer range. Bone-like apatite deposition ability of diopside scaffolds was examined under static and circulation mode of SBF (Simulated Body Fluid). It was noticed that diopside has the capability to deposit HAP (hydroxyapatite) within the early stages of immersion. ICP-OES analysis indicates release of Ca, Mg, Si ions and removal of P ions from the SBF, but in different quantities from diopside scaffolds. Cytocompatability studies on human bone marrow stromal cells (hBMSCs) revealed good cellular attachment on the surface of diopside scaffolds and formation of extracellular matrix (ECM). This study suggests that the usage of eggshell biowaste as calcium source provides an effective substitute for synthetic starting materials to fabricate bioproducts for biomedical applications. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Revealing Invisible Beauty, Ultra Detailed: The Influence of Low Cost UV Exposure on Natural History Specimens in 2D+ Digitization

    PubMed Central

    Brecko, Jonathan; Mathys, Aurore; Dekoninck, Wouter; De Ceukelaire, Marleen; VandenSpiegel, Didier; Semal, Patrick

    2016-01-01

    Digitization of the natural history specimens usually occurs by taking detailed pictures from different sides or producing 3D models. Additionally this is normally limited to imaging the specimen while exposed by light of the visual spectrum. However many specimens can see in or react to other spectra as well. Fluorescence is a well known reaction to the ultraviolet (UV) spectrum by animals, plants, minerals etc. but rarely taken into account while examining natural history specimens. Our tests show that museum specimens still fluoresce when exposed to UV light of 395 nm and 365 nm, even after many years of preservation. When the UV exposure is used in the digitization of specimens using our low cost focus stacking (2D+) setup, the resulting pictures reveal more detail than the conventional 2D+ images. Differences in fluorescence using 395 nm or 365 nm UV lights were noticed, however there isn’t a preferred wavelength as some specimens react more to the first, while others have better results with the latter exposure. Given the increased detail and the low cost of the system, UV exposure should be considered while digitizing natural history museum collections. PMID:27536993

  16. Applications of just-noticeable depth difference model in joint multiview video plus depth coding

    NASA Astrophysics Data System (ADS)

    Liu, Chao; An, Ping; Zuo, Yifan; Zhang, Zhaoyang

    2014-10-01

    A new multiview just-noticeable-depth-difference(MJNDD) Model is presented and applied to compress the joint multiview video plus depth. Many video coding algorithms remove spatial and temporal redundancies and statistical redundancies but they are not capable of removing the perceptual redundancies. Since the final receptor of video is the human eyes, we can remove the perception redundancy to gain higher compression efficiency according to the properties of human visual system (HVS). Traditional just-noticeable-distortion (JND) model in pixel domain contains luminance contrast and spatial-temporal masking effects, which describes the perception redundancy quantitatively. Whereas HVS is very sensitive to depth information, a new multiview-just-noticeable-depth-difference(MJNDD) model is proposed by combining traditional JND model with just-noticeable-depth-difference (JNDD) model. The texture video is divided into background and foreground areas using depth information. Then different JND threshold values are assigned to these two parts. Later the MJNDD model is utilized to encode the texture video on JMVC. When encoding the depth video, JNDD model is applied to remove the block artifacts and protect the edges. Then we use VSRS3.5 (View Synthesis Reference Software) to generate the intermediate views. Experimental results show that our model can endure more noise and the compression efficiency is improved by 25.29 percent at average and by 54.06 percent at most compared to JMVC while maintaining the subject quality. Hence it can gain high compress ratio and low bit rate.

  17. Child abuse: discovering the horrifying truth.

    PubMed

    Blair, Lee; Clauss, Eric; Meredith, Mark

    2011-10-01

    EMS is called to the residence of a 2-month-old child who's lethargic and has not eaten well for several days. On arrival, the grandmother of the patient states she's concerned because the child isn't acting right. During your assessment, you notice the child isn't acting age appropriate. Initial vital signs after placing the patient in the ambulance reveal: blood pressure 82/46, pulse 146 bpm, respirations 32 and a blood-glucose level of 134 mg/dL. Further assessment reveals bruising to the pinna of the right ear. On arrival at the emergency department (ED), the child begins to have periods of apnea, and the hospital healthcare providers intubate the patient. A post-intubation chest X-ray reveals multiple acute and sub-acute rib fractures. The ED staff exposed the patient during their assessment and noted bruising to the left ear and the jaw. There's also bruising found in different stages of healing to the anterior and posterior chest wall. The ED staff suspects this patient is a victim of child maltreatment, so the proper authorities are notified. During the investigation, the mother admits to abusing the child. Copyright © 2011 Elsevier Inc. All rights reserved.

  18. Changes in reflectance anisotropy of wheat crop during different phenophases

    NASA Astrophysics Data System (ADS)

    Lunagaria, Manoj M.; Patel, Haridas R.

    2017-04-01

    The canopy structure of wheat changes significantly with growth stages and leads to changes in reflectance anisotropy. Bidirectional reflectance distribution function characterises the reflectance anisotropy of the targets, which can be approximated. Spectrodirectional reflectance measurements on wheat crop were acquired using a field goniometer system. The bidirectional reflectance spectra were acquired at 54 view angles to cover the hemispheric span up to 60° view zenith. The observations were made during early growth stages till maturity of the crop. The anisotropy was not constant for all wavelengths and anisotropic factors clearly revealed spectral dependence, which was more pronounced in near principal plane. In near infrared, wheat canopy expressed less reflectance anisotropy because of higher multiple scattering. The broad hotspot signature was noticeable in reflectance of canopy whenever view and solar angles were close. Distinct changes in bidirectional reflectance distribution function were observed during booting to flowering stages as the canopy achieves more uniformity, height and head emergence. The function clearly reveals bowl shape during heading to early milking growth stages of the crop. Late growth stages show less prominent gap and shadow effects. Anisotropy index revealed that wheat exhibits changes in reflectance anisotropy with phenological development and with spectral bands.

  19. Stylistic Variations in Science Lectures: Teaching Vocabulary.

    ERIC Educational Resources Information Center

    Jackson, Jane; Bilton, Linda

    1994-01-01

    Twenty lectures by native speaker geology lecturers to nonnative speaker students were transcribed, and 921 instances of vocabulary elaboration were coded into a computer database according to 20 linguistic features. Analysis revealed noticeable variation among lecturers in language range/technicality, vocabulary elaboration, signalling, and use…

  20. 75 FR 3542 - Rehabilitation Research and Development Service Scientific Merit Review Board; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... unwarranted invasion of personal privacy. Disclosure would also reveal research proposals and research... DEPARTMENT OF VETERANS AFFAIRS Rehabilitation Research and Development Service Scientific Merit... (Federal Advisory Committee Act) that the Rehabilitation Research and Development Service Scientific Merit...

  1. 76 FR 65213 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-20

    ... AEROTEK Commerical Staffing, San Diego, CA; FLEXTRONICS International USA, Inc., Infrastructure Division... Diego, California (subject firm). The Department's Notice was published in the Federal Register on... information provided by Flextronics International USA, Inc. revealed that workers of the Infrastructure...

  2. Clutter in electronic medical records: examining its performance and attentional costs using eye tracking.

    PubMed

    Moacdieh, Nadine; Sarter, Nadine

    2015-06-01

    The objective was to use eye tracking to trace the underlying changes in attention allocation associated with the performance effects of clutter, stress, and task difficulty in visual search and noticing tasks. Clutter can degrade performance in complex domains, yet more needs to be known about the associated changes in attention allocation, particularly in the presence of stress and for different tasks. Frequently used and relatively simple eye tracking metrics do not effectively capture the various effects of clutter, which is critical for comprehensively analyzing clutter and developing targeted, real-time countermeasures. Electronic medical records (EMRs) were chosen as the application domain for this research. Clutter, stress, and task difficulty were manipulated, and physicians' performance on search and noticing tasks was recorded. Several eye tracking metrics were used to trace attention allocation throughout those tasks, and subjective data were gathered via a debriefing questionnaire. Clutter degraded performance in terms of response time and noticing accuracy. These decrements were largely accentuated by high stress and task difficulty. Eye tracking revealed the underlying attentional mechanisms, and several display-independent metrics were shown to be significant indicators of the effects of clutter. Eye tracking provides a promising means to understand in detail (offline) and prevent (in real time) major performance breakdowns due to clutter. Display designers need to be aware of the risks of clutter in EMRs and other complex displays and can use the identified eye tracking metrics to evaluate and/or adjust their display. © 2015, Human Factors and Ergonomics Society.

  3. Reported awareness of tobacco advertising and promotion in China compared to Thailand, Australia and the USA.

    PubMed

    Li, L; Yong, H-H; Borland, R; Fong, G T; Thompson, M E; Jiang, Y; Yang, Y; Sirirassamee, B; Hastings, G; Harris, F

    2009-06-01

    China currently does not have comprehensive laws or regulations on tobacco advertising and promotion, although it ratified the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) in October 2005 and promised to ban all tobacco advertising by January 2011. Much effort is needed to monitor the current situation of tobacco advertising and promotion in China. This study aims to examine levels of awareness of tobacco advertising and promotion among smokers in China as compared to other countries with different levels of restrictions. One developing country (Thailand) and two developed countries (Australia and the USA) were selected for comparison. All four countries are part of the International Tobacco Control (ITC) Policy Evaluation Survey project. Between 2005 and 2006, parallel ITC surveys were conducted among adult smokers (at least smoked weekly) in China (n = 4763), Thailand (n = 2000), Australia (n = 1767) and the USA (n = 1780). Unprompted and prompted recall of noticing tobacco advertising and promotion were measured. Chinese respondents reported noticing tobacco advertisements in a range of channels and venues, with highest exposure levels on television (34.5%), billboards (33.4%) and in stores (29.2%). A quarter of respondents noticed tobacco sponsorships, and a high level of awareness of promotion was reported. Cross-country comparison reveals that overall reported awareness was significantly higher in China than in Thailand (particularly) and Australia, but lower than in the USA. There is a big gap between China and the better-performing countries such as Thailand and Australia regarding tobacco promotion restrictions. China needs to do more, including enhanced policy and more robust enforcement.

  4. Different Kinds of Birthmarks

    MedlinePlus

    ... Us Media contacts Advertising contacts AAD logo Advertising, marketing and sponsorships Legal notice Copyright © 2018 American Academy ... prohibited without prior written permission. AAD logo Advertising, marketing and sponsorships Legal notice Copyright © 2017 American Academy ...

  5. Bibliometric approach of factors affecting scientific productivity in environmental sciences and ecology.

    PubMed

    Dragos, Cristian Mihai; Dragos, Simona Laura

    2013-04-01

    Different academic bibliometric studies have measured the influence of economic, political and linguistic factors in the academic output of countries. Separate analysis in different fields can reveal specific incentive factors. Our study proves that the Environmental Performance Index, computed by Yale University, is highly significant (p<0.01) for the productivity of research and development activities in environmental sciences and ecology. The control variables like education financing, publishing of ISI Thomson domestic journals and the English language are also significant. The methodology uses Ordinary Least Squares multiple regressions with convincing results (R(2)=0.752). The relative positions of the 92 countries in the sample are also discussed. We draw up a ranking of the countries' concern for the environment, considering evenly the scientific productivity and the environment quality. We notice huge differences concerning the number of inhabitants and population income between the countries that dominate the classification and those occupying the last positions. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. 76 FR 61749 - Notice of Revised Determination on Reconsideration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ..., Inc., including leased workers from SPS Temporaries, Depew, New York (TA-W-73,441G), engaged in the production of paperback books. The reconsideration investigation revealed that the following worker groups..., Mt. Morris, Illinois; and Quad Graphics, Inc., Depew, New York, meet the worker group certification...

  7. WSU-IR at TREC 2015 Clinical Decision Support Track: Joint Weighting of Explicit and Latent Medical Query Concepts from Diverse Sources

    DTIC Science & Technology

    2015-11-20

    noticed erythematous rash on the girl’s trunk. Physical examination reveals strawberry red tongue, red and cracked lips, and swollen red hands. The whites...as erythematous rash, and test results, such as revealed swollen red hands and strawberry red tongue, as well as indicates a possible di- agnosis...such as strawberry tongue (also known as Kawasaki disease). Although such queries are fairly long, only a fraction of concepts corresponding to an in

  8. Discrimination of phoneme length differences in word and sentence contexts

    NASA Astrophysics Data System (ADS)

    Kawai, Norimune; Carrell, Thomas

    2005-09-01

    The ability of listeners to discriminate phoneme duration differences within word and sentence contexts was measured. This investigation was part of a series of studies examining the audibility and perceptual importance of speech modifications produced by stuttering intervention techniques. Just noticeable differences (jnd's) of phoneme lengths were measured via the parameter estimation by sequential testing (PEST) task, an adaptive tracking procedure. The target phonemes were digitally manipulated to vary from normal (130 m) to prolonged (210 m) duration in 2-m increments. In the first condition the phonemes were embedded in words. In the second condition the phonemes were embedded within words, which were further embedded in sentences. A four-interval forced-choice (4IAX) task was employed on each trial, and the PEST procedure determined the duration at which each listener correctly detected a difference between the normal duration and the test duration 71% of the time. The results revealed that listeners were able to reliably discriminate approximately 15-m differences in word context and 10-m differences in sentence context. An independent t-test showed a difference in discriminability between word and sentence contexts to be significant. These results indicate that duration differences were better perceived within a sentence context.

  9. 42 CFR 1001.2002 - Notice of exclusion.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... exchanges required under § 1005.8 of this chapter, the OIG may amend its notice letter if information comes to light that justifies the imposition of a different period of exclusion other than the one proposed...

  10. 42 CFR 1001.2002 - Notice of exclusion.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... exchanges required under § 1005.8 of this chapter, the OIG may amend its notice letter if information comes to light that justifies the imposition of a different period of exclusion other than the one proposed...

  11. Educational Differences in Associations of Noticing Anti-Tobacco Information with Smoking-Related Attitudes and Quit Intentions: Findings from the International Tobacco Control Europe Surveys

    ERIC Educational Resources Information Center

    Springvloet, L.; Willemsen, M. C.; Mons, U.; van den Putte, B.; Kunst, A. E.; Guignard, R.; Hummel, K.; Allwright, S.; Siahpush, M.; de Vries, H.; Nagelhout, G. E.

    2015-01-01

    This study examined educational differences in associations of noticing anti-tobacco information with smoking-related attitudes and quit intentions among adult smokers. Longitudinal data (N = 7571) from two waves of six countries of the International Tobacco Control (ITC) Europe Surveys were included. Generalized estimating equation analyses and…

  12. 76 FR 2147 - UAW-Chrysler National Training Center Technology Training Joint Programs Staff, Detroit, MI; UAW...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-12

    ... Technical Training Center Technology Training Joint Programs Staff, Warren, MI; Notice of Revised... facilities. The information revealed that the technical training provided (such as applied industrial... engaged in employment related to the supply of technical training services, meet the worker group...

  13. 75 FR 40036 - Rehabilitation Research and Development Service Scientific Merit Review Board; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-13

    .... Disclosure would also reveal research proposals and research underway which could lead to the loss of these... DEPARTMENT OF VETERANS AFFAIRS Rehabilitation Research and Development Service Scientific Merit... (Federal Advisory Committee Act) that the Rehabilitation Research and Development Service Scientific Merit...

  14. Gatsby as a Drowned Sailor.

    ERIC Educational Resources Information Center

    Lukens, Margaret

    1987-01-01

    Claims that most teachers who read "The Great Gatsby" in high school English courses do not notice the work's extensive use of nautical imagery. Cites examples and claims that close reading reveals Gatsby to be not only the dreamer and unsuccessful suitor but also the American fisherman who "hooks a big one." (JD)

  15. 76 FR 35476 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-17

    ...' industry (i.e., conditions within the industry are adverse). Affirmative Determinations for Worker...' industry are not adverse. None. Negative Determinations for Worker Adjustment Assistance and Alternative...,095; 6ixSigma Apparel Network, LLC, New York, NY. The investigation revealed that criteria of Section...

  16. Size-related cytotoxicological aspects of polyvinylpyrrolidone-capped platinum nanoparticles.

    PubMed

    Buchtelova, Hana; Dostalova, Simona; Michalek, Petr; Krizkova, Sona; Strmiska, Vladislav; Kopel, Pavel; Hynek, David; Richtera, Lukas; Ridoskova, Andrea; Adam, Pavlina; Kynicky, Jindrich; Brtnicky, Martin; Heger, Zbynek; Adam, Vojtech

    2017-07-01

    The nanotechnological concept is based on size-dependent properties of particles in the 1-100 nm range. Nevertheless, the connection between their size and effect is still not clear. Thus, we focused on reductive colloidal synthesis, characterization and biological testing of Pt nanoparticles (PtNPs) capped with biocompatible polymer polyvinylpyrrolidone (PVP). Synthesized PtNPs were of 3 different primary sizes (approx. ∼10; ∼14 and > 20 nm) and demonstrated exceptional haemocompatibility. In vitro treatment of three different types of malignant cells (prostate - LNCaP, breast - MDA-MB-231 and neuroblastoma - GI-ME-N) revealed that even marginal differences in PtNPs diameter resulted in changes in their cytotoxicity. The highest cytotoxicity was observed using the smallest PtNPs-10, where 24IC 50 was lower (3.1-6.2 μg/mL) than for cisplatin (8.1-19.8 μg/mL). In contrast to MDA-MB-231 and LNCaP cells, in GI-ME-N cells PtNPs caused noticeable changes in their cellular structure without influencing their viability. Post-exposure analyses revealed that PtNPs-29 and PtNPs-40 were capable of forming considerably higher amount of reactive oxygen species with consequent stimulation of expression of metallothionein (MT1/2 and MT3), at both mRNA and protein level. Overall, our pilot study demonstrates that in the nanoscaled world even the smallest differences can have crucial biological effect. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Exploring reserve lots of Cymbopogon citratus, Aloysia citrodora and Thymus × citriodorus as improved sources of phenolic compounds.

    PubMed

    Rita, Ingride; Pereira, Carla; Barros, Lillian; Ferreira, Isabel C F R

    2018-08-15

    Given the increasing consumers demand for novelty, tea companies have been presenting new added value products such as reserve lots of aromatic plants. Herein, infusions from different lots of three aromatic plants were assessed in terms of phenolic composition (HPLC-DAD-ESI/MS) and antioxidant properties (reducing power, free radical scavenging and lipid peroxidation inhibition capacity). Cymbopogon citratus (C. citratus; main compound 5-O-caffeoylquinic acid) and Aloysia citrodora (A. citrodora; prevalence of verbascoside) reserve lots revealed higher phenolic compounds concentration than the respective standard lots. Thymus × citriodorus (T. citriodorus; main compound rosmarinic acid) standard lot presented higher amounts of phenolic acids than the reserve lot, nonetheless, total flavonoids and phenolic compounds were not significantly different. The differences between both lots antioxidant activity were more noticeable in C. citratus, with the reserve lot presenting the highest activity. This study provides evidence of the differences between these plants chemical composition and bioactivity depending on the harvesting conditions. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. Growth of defect-free GaAsSbN axial nanowires via self-catalyzed molecular beam epitaxy

    NASA Astrophysics Data System (ADS)

    Sharma, Manish; Deshmukh, Prithviraj; Kasanaboina, Pavan; Reynolds, C. Lewis, Jr.; Liu, Yang; Iyer, Shanthi

    2017-12-01

    Bandgap reduction of 10% by incorporation of a dilute amount of N is reported for the first time, in axial GaAsSb nanowires (NWs) grown on Si (111) via Ga-assisted molecular beam epitaxy. Impact of N incorporation on the surface morphology, NW growth kinetics, and their structural and optical properties were examined. Dilute nitride NWs with Sb composition of 7 at% did not exhibit any noticeable planar defects, as revealed by the absence of satellite twin peaks in the selected-area diffraction pattern and high-resolution transmission electron microscopy imaging. Point defects were also minimal in as-grown dilute nitride NWs, as ascertained from the comparison of low-temperature photoluminescence spectra as well as the shape and shift of Raman modes, with in situ annealed NWs in different ambients. Evidence of enhanced incorporation of N was found in the NWs in situ annealed in N ambient, but with deteriorated optical quality due to simultaneous creation of N-induced defects. The lack of any noticeable defects in the as-grown GaAsSbN NWs demonstrates the advantage of the vapor-liquid-solid mechanism responsible for growth of axial configuration over the vapor-solid growth mechanism for core-shell NWs as well as their thin film counterpart, which commonly exhibit N-induced point defects.

  19. Cyclin-dependent Kinase 5: Novel role of gene variants identified in ADHD.

    PubMed

    Maitra, Subhamita; Chatterjee, Mahasweta; Sinha, Swagata; Mukhopadhyay, Kanchan

    2017-07-28

    Cortical neuronal migration and formation of filamentous actin cytoskeleton, needed for development, normal cell growth and differentiation, are regulated by the cyclin-dependent kinase 5 (Cdk5). Attention deficit hyperactivity disorder (ADHD) is associated with delayed maturation of the brain and hence we hypothesized that cdk5 may have a role in ADHD. Eight functional CDK5 gene variants were analyzed in 848 Indo-Caucasoid individuals including 217 families with ADHD probands and 250 healthy volunteers. Only three variants, rs2069454, rs2069456 and rs2069459, predicted to affect transcription, were found to be bimorphic. Significant difference in rs2069456 "AC" genotype frequency was noticed in the probands, more specifically in the males. Family based analysis revealed over transmission of rs2069454 "C" and rs2069456 "A" to the probands. Quantitative trait analysis exhibited association of haplotypes with inattention, domain specific impulsivity, and behavioral problem, though no significant contribution was noticed on the age of onset of ADHD. Gene variants also showed significant association with cognitive function and co-morbidity. Probands having rs2069459 "TT" showed betterment during follow up. It may be inferred from this pilot study that CDK5 may affect ADHD etiology, possibly by attenuating synaptic neurotransmission and could be a useful target for therapeutic intervention.

  20. Identification of evolutionarily conserved Momordica charantia microRNAs using computational approach and its utility in phylogeny analysis.

    PubMed

    Thirugnanasambantham, Krishnaraj; Saravanan, Subramanian; Karikalan, Kulandaivelu; Bharanidharan, Rajaraman; Lalitha, Perumal; Ilango, S; HairulIslam, Villianur Ibrahim

    2015-10-01

    Momordica charantia (bitter gourd, bitter melon) is a monoecious Cucurbitaceae with anti-oxidant, anti-microbial, anti-viral and anti-diabetic potential. Molecular studies on this economically valuable plant are very essential to understand its phylogeny and evolution. MicroRNAs (miRNAs) are conserved, small, non-coding RNA with ability to regulate gene expression by bind the 3' UTR region of target mRNA and are evolved at different rates in different plant species. In this study we have utilized homology based computational approach and identified 27 mature miRNAs for the first time from this bio-medically important plant. The phylogenetic tree developed from binary data derived from the data on presence/absence of the identified miRNAs were noticed to be uncertain and biased. Most of the identified miRNAs were highly conserved among the plant species and sequence based phylogeny analysis of miRNAs resolved the above difficulties in phylogeny approach using miRNA. Predicted gene targets of the identified miRNAs revealed their importance in regulation of plant developmental process. Reported miRNAs held sequence conservation in mature miRNAs and the detailed phylogeny analysis of pre-miRNA sequences revealed genus specific segregation of clusters. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Periodic Variations in Low-Latitudinal Ionosphere during Stratospheric Sudden Warming Event in 2016/2017 Winter

    NASA Astrophysics Data System (ADS)

    Liu, J.; Zhang, D.

    2017-12-01

    With datasets of electron density, neutral wind, ionosonde, neutral temperature, and geomagnetism, we studied the low-latitudinal ionosphere in East-Asia sector during Stratospheric Sudden Warming (SSW) Event in 2016/2017 winter, and some periodic variations in several parameters were revealed. A notable quasi-14.5-day (Q14.5D) period was detected in the strength and location of the northern equatorial ionospheric anomaly (EIA) crest shown with total electron content (TEC). As comparison, northern EIA crest in the American sector had similar characters. With data from Wuhan meteor radar and Yunnan MF radar, we found that, within altitude ranging from 80-100 km, wind field also showed above-mentioned periodic variation, which varied in different heights and stations. The Q14.5D period was also revealed in critical frequency (foF2) and peak altitude (hmF2) of F2 layer from two ionosonde stations in southern China. From electron density of Defense Meteorological Satellite Program (DMSP) and TEC of Metop-A, it was shown that this period component is also noticeable in the topside ionosphere above 800 km. However, this character is different in EEJ, of which the Morlet wavelet showed higher strength in quasi-7.5-day period compared to its Q14.5D component.

  2. Teacher Knowledge for Active-Learning Instruction: Expert-Novice Comparison Reveals Differences.

    PubMed

    Auerbach, A J; Higgins, M; Brickman, P; Andrews, T C

    2018-01-01

    Active-learning strategies can improve science, technology, engineering, and mathematics (STEM) undergraduates' abilities to learn fundamental concepts and skills. However, the results instructors achieve vary substantially. One explanation for this is that instructors commonly implement active learning differently than intended. An important factor affecting how instructors implement active learning is knowledge of teaching and learning. We aimed to discover knowledge that is important to effective active learning in large undergraduate courses. We developed a lesson-analysis instrument to elicit teacher knowledge, drawing on the theoretical construct of teacher noticing. We compared the knowledge used by expert ( n = 14) and novice ( n = 29) active-learning instructors as they analyzed lessons. Experts and novices differed in what they noticed, with experts more commonly considering how instructors hold students accountable, topic-specific student difficulties, whether the instructor elicited and responded to student thinking, and opportunities students had to generate their own ideas and work. Experts were also better able to support their lesson analyses with reasoning. This work provides foundational knowledge for the future design of preparation and support for instructors adopting active learning. Improving teacher knowledge will improve the implementation of active learning, which will be necessary to widely realize the potential benefits of active learning in undergraduate STEM. © 2018 A. J. Auerbach et al. CBE—Life Sciences Education © 2018 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  3. 77 FR 13070 - Notice of Request for Approval of a New Information Collection for Export/Health Certificate Forms

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ... as negotiations continue with more countries. DATES: Comments on this notice must be received by May... 16 different export certificate request forms with ongoing negotiations with at least 5 more...

  4. Reported awareness of tobacco advertising and promotion in China compared to Thailand, Australia and the USA

    PubMed Central

    Li, L; Yong, H-H; Borland, R; Fong, G T; Thompson, M E; Jiang, Y; Yang, Y; Sirirassamee, B; Hastings, G; Harris, F

    2009-01-01

    Background: China currently does not have comprehensive laws or regulations on tobacco advertising and promotion, although it ratified the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) in October 2005 and promised to ban all tobacco advertising by January 2011. Much effort is needed to monitor the current situation of tobacco advertising and promotion in China. Objective: This study aims to examine levels of awareness of tobacco advertising and promotion among smokers in China as compared to other countries with different levels of restrictions. Methods: One developing country (Thailand) and two developed countries (Australia and the USA) were selected for comparison. All four countries are part of the International Tobacco Control (ITC) Policy Evaluation Survey project. Between 2005 and 2006, parallel ITC surveys were conducted among adult smokers (at least smoked weekly) in China (n = 4763), Thailand (n = 2000), Australia (n = 1767) and the USA (n = 1780). Unprompted and prompted recall of noticing tobacco advertising and promotion were measured. Results: Chinese respondents reported noticing tobacco advertisements in a range of channels and venues, with highest exposure levels on television (34.5%), billboards (33.4%) and in stores (29.2%). A quarter of respondents noticed tobacco sponsorships, and a high level of awareness of promotion was reported. Cross-country comparison reveals that overall reported awareness was significantly higher in China than in Thailand (particularly) and Australia, but lower than in the USA. Conclusions: There is a big gap between China and the better-performing countries such as Thailand and Australia regarding tobacco promotion restrictions. China needs to do more, including enhanced policy and more robust enforcement. PMID:19332425

  5. 75 FR 3253 - Lamb Assembly and Test, LLC, Subsidiary of Mag Industrial Automation Systems, Machesney Park, IL...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ..., LLC, Subsidiary of Mag Industrial Automation Systems, Machesney Park, IL; Notice of Negative... automation equipment and machine tools did not contribute to worker separations at the subject facility and...' firm's declining customers. The survey revealed no imports of automation equipment and machine tools by...

  6. 76 FR 81990 - 2002 Reopened-Previously Denied Determinations; Notice of Negative Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... reconsideration investigation revealed that the following workers groups have not met the certification criteria... Myers, FL. TA-W-80,026; Computer Task Group, Mechanicsburg, PA. TA-W-80,047; Cenveo, Inc., Springfield... Department's Web site at tradeact/taa/taa--search--form.cfm under the searchable listing of determinations or...

  7. 76 FR 76189 - 2002 Reopened-Previously Denied Determinations; Notice of Revised Denied Determinations on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-06

    ... reconsideration investigation revealed that the following workers groups have met the certification criteria under... Salt Lake City, UT: March 24, 2010. TA-W-80,153; Intercontinental Hotels Group, Alpharetta, GA: May 4... available on the Department's Web site at tradeact/taa/taa-- search--form.cfm under the searchable listing...

  8. Empathetic and Pro-Social Awareness in Primary School Students: A Case Study

    ERIC Educational Resources Information Center

    Dar, Fatima Rehan

    2016-01-01

    The study addressed a cognitive-affective gap in a primary English curriculum and noticed whether the curriculum, texts and class activities utilized empathetic and pro-social themes in teaching English language. The findings from the document review, interviews and observations revealed that the said themes were underrepresented in the…

  9. 76 FR 46854 - Wausau Daily Herald, Advertising Production Division, a Subsidiary of Gannett Co., Inc.,Wausau...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ..., Advertising Production Division, a Subsidiary of Gannett Co., Inc.,Wausau, WI; Notice of Negative...) applicable to workers and former workers of Wausau Daily Herald, Advertising Production Division, a... information revealed that 2AdPro (an advertising firm located in India) handled an insignificant amount of...

  10. 76 FR 44338 - Notice of Public Meeting on the NIOSH Document Titled: “Criteria for a Recommended Standard...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-25

    ..., medical surveillance, and personal protective equipment; 6. Oral comments provided to NIOSH on the draft... where individuals sign up to make public comments. If individuals in making a statement reveal personal..., including any personal information provided. CONTACT PERSON FOR MORE INFORMATION: Lauralynn Taylor McKernan...

  11. The Effects of Two Types of Exposure on Attitudes toward Aspects of Juvenile Delinquency.

    ERIC Educational Resources Information Center

    LeUnes, Arnold; And Others

    1996-01-01

    Tracks the attitude changes of a group of abnormal psychology students following a tour of a juvenile correctional facility and a presentation by four of the inmates. A 25-item semantic differential scale revealed a noticeable improvement in the students' attitudes towards juvenile delinquents after the visit. (MJP)

  12. 75 FR 65523 - Dawson Metal Company, Inc., Industrial Division, Jamestown, NY; Notice of Negative Determination...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ... reconsideration investigation revealed that the workers are separately identifiable by product line and that the... separately identifiable by product line, the Department did not survey this customer. Conclusion After a... competitive with the articles produced by the workers during the relevant period and did not shift to a...

  13. 77 FR 27082 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-08

    ... publicly identified by name by the International Trade Commission as a member of a domestic industry in an... date 81,249 Jump Clothing, Inc., Sweet Los Angeles, CA....... February 13, 2010. Rain Apparel. The... COM Corp Industries, ISATEC Garfield Heights, OH Technical Center. The investigation revealed that the...

  14. New multi-site observations of the delta Scuti stars BS and BT Cancri. Results of the STEPHI VII campaign on the Praesepe cluster

    NASA Astrophysics Data System (ADS)

    Hernandez, M. M.; Michel, E.; Belmonte, J. A.; Jiang, S. Y.; Alvarez, M.; Chevreton, M.; Paparo, M.; Kjeldsen, H.; Bauduin, D.; Fromage, J.; Goupil, M. J.; Li, Z. P.; Liu, Y. Y.; Mangeney, A.; Massacrier, G.; Ringot, O.; Cortes, T. Roca; Servan, B.; Vidal, I.

    1998-09-01

    New observations of BS and BT Cnc were performed during the STEPHI VII campaign in 1996 February. An overall run of 115 hours of data was collected. Different methods have been used to analyse the time series, bringing the detection of 2 frequencies for BT Cnc and 3 frequencies for BS Cnc above the 99% confidence level. A comparison with the literature reveals that the dominant mode of BT Cnc ( ~ 9.8 c/d) has kept excited over tens of years, while the secondary modes have not been the same all the time. However, during the very last years the two frequencies detected by us have been the only ones noticeably excited in the spectrum.

  15. Ultrastructural effects on gill tissues induced in red tilapia Oreochromis sp. by a waterborne lead exposure.

    PubMed

    Aldoghachi, Mohammed A; Azirun, Mohd Sofian; Yusoff, Ismail; Ashraf, Muhammad Aqeel

    2016-09-01

    Experiments on hybrid red tilapia Oreochromis sp. were conducted to assess histopathological effects induced in gill tissues of 96 h exposure to waterborne lead (5.5 mg/L). These tissues were investigated by light and scanning electron microscopy. Results showed that structural design of gill tissues was noticeably disrupted. Major symptoms were changes of epithelial cells, fusion in adjacent secondary lamellae, hypertrophy and hyperplasia of chloride cells and coagulate necrosis in pavement cells with disappearance of its microridges. Electron microscopic X-ray microanalysis of fish gills exposed to sublethal lead revealed that lead accumulated on the surface of the gill lamella. This study confirmed that lead exposure incited a difference of histological impairment in fish, supporting environmental watch over aquatic systems when polluted by lead.

  16. Pectin functionalised by fatty acids: Diffuse reflectance infrared Fourier transform (DRIFT) spectroscopic characterisation

    NASA Astrophysics Data System (ADS)

    Kamnev, Alexander A.; Calce, Enrica; Tarantilis, Petros A.; Tugarova, Anna V.; De Luca, Stefania

    2015-01-01

    Chemically modified pectin derivatives obtained by partial esterification of its hydroxyl moieties with fatty acids (FA; oleic, linoleic and palmitic acids), as well as the initial apple peel pectin were comparatively characterised using diffuse reflectance infrared Fourier transform (DRIFT) spectroscopy. Characteristic changes observed in DRIFT spectra in going from pectin to its FA esters are related to the corresponding chemical modifications. Comparing the DRIFT spectra with some reported data on FTIR spectra of the same materials measured in KBr or NaCl matrices has revealed noticeable shifts of several polar functional groups both in pectin and in its FA-esterified products induced by the halide salts. The results obtained have implications for careful structural analyses of biopolymers with hydrophilic functional groups by means of different FTIR spectroscopic methodologies.

  17. Studying dielectric mechanism and magnetization of double perovskite Gd2NiMnO6 ceramic

    NASA Astrophysics Data System (ADS)

    Mohapatra, S. R.; Sahu, B.; Kaushik, S. D.; Singh, A. K.

    2016-05-01

    In the present work, the structure, dielectric and magnetic properties of Gd2NiMnO6 double perovskite have been studied. X-Ray diffraction study reveals the phase pure formation of the material that crystallizes into monoclinic phase (space group 'P21/n'). Surface morphology depicts heterogeneous grain distribution with average grain size of ~1 µm. Temperature dependent (50 - 330 K) dielectric measurements at different frequencies (0.5 - 50 kHz) relate to Maxwell-Wagner interfacial polarization model. Giant dielectric constant at 1 kHz for 300 K (ɛ' ~1900) is noticed as compared to that of 50 K (ɛ' ~10) coupled with a peak shift in tan loss towards higher temperature with frequency. The activation energy (0.24 eV) obtained using Arrhenius relation for thermally activated relaxor behavior of the material signifies an electron hopping mechanism between Ni2+ and Mn4+ cations. Lastly, M-H study shows `S' shape hysteresis loop at 50 K with remnant magnetization (Mr) of 0.72 µB/f.u. along with a linear plot for 300 K which reveals paramagnetic nature of the material.

  18. Phenol and chlorinated phenols exhibit different apoptotic potential in human red blood cells (in vitro study).

    PubMed

    Michałowicz, Jaromir; Włuka, Anna; Cyrkler, Monika; Maćczak, Aneta; Sicińska, Paulina; Mokra, Katarzyna

    2018-05-23

    Phenol and chlorinated phenols are widely spread in the environment and human surrounding, which leads to a common environmental and occupational exposure of humans to these substances. The aim of this study was to assess eryptotic changes in human red blood cells treated with phenol, 2,4-dichlorophenol (2,4-DCP), 2,4,6-trichlorophenol (2,4,6-TCP) and pentachlorophenol (PCP). The erythrocytes were incubated with phenols studied in the concentrations ranging from 1 to 100 μg/mL for 24 h or 48 h. The results of the study revealed that all compounds studied caused phosphatidylserine translocation and increased cytosolic calcium ions level in human erythrocytes. It was also noticed that phenol and chlorophenols caused an increase in caspase-3 and calpain activation, which confirmed that they were capable of inducing suicidal death of erythrocytes. The results also revealed that PCP most strongly altered the parameters studied, while phenol exhibited the weakest eryptotic potential in the incubated cells. Copyright © 2018 Elsevier B.V. All rights reserved.

  19. Quantitative proteomic analysis reveals proteins involved in the neurotoxicity of marine medaka Oryzias melastigma chronically exposed to inorganic mercury.

    PubMed

    Wang, Yuyu; Wang, Dazhi; Lin, Lin; Wang, Minghua

    2015-01-01

    Mercury is a ubiquitous environmental contaminant which exerts neurotoxicity upon animals. Nevertheless, the molecular mechanisms involved in inorganic mercury neurotoxicity are unknown. We investigated protein profiles of marine medaka, chronically exposed to mercuric chloride using two-dimensional difference gel electrophoresis (2D-DIGE) and matrix-assisted laser desorption/ionization tandem time-of-flight mass spectrometry (MALDI-TOF-TOF MS) analysis. The mercury accumulation and ultrastructure were also examined in the brain. The results showed that mercury was significantly accumulated in the treated brain, and subsequently caused a noticeable damage. The comparison of 2D-DIGE protein profiles between the control and treatment revealed that 16 protein spots were remarkably altered in abundance, which were further submitted for MALDI-TOF-TOF MS analysis. The identified proteins indicated that inorganic mercury may cause neurotoxicity through the induction of oxidative stress, cytoskeletal assembly dysfunction and metabolic disorders. Thus, this study provided a basis for a better understanding of the molecular mechanisms involved in mercury neurotoxicity. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Effects of moist- and dry-heat cooking on the meat quality, microstructure and sensory characteristics of native chicken meat.

    PubMed

    Chumngoen, Wanwisa; Chen, Chih-Feng; Tan, Fa-Jui

    2018-01-01

    This study investigates the effects of moist- (water-cooking; WC) and dry-heat (oven-cooking; OC) on the quality, microstructure and sensory characteristics of native chicken breast meat. The results revealed that OC meat had a significantly higher cooking time, cooking loss, and shear force values and lower L* values. Protein solubility decreased after cooking in both cooking methods; however, no statistical difference was observed between WC and OC meats, whereas collagen solubility and myofibrillar fragmentation index (MFI) increased after cooking and WC meat exhibited higher collagen solubility and MFI (P < 0.05). The fiber diameter and sarcomere length decreased substantially after cooking, and fibril shrinkage was noticeable in OC meat (P < 0.05). Descriptive sensory analysis revealed that WC meat exhibited a significantly higher moisture release and lower initial hardness, chewdown hardness and residual loose particles. A darker color and enhanced chickeny flavor were observed for OC meat. Based on the unique sensory and physicochemical characteristics in demand, producers should employ appropriate cooking methods to optimize native chicken meat quality. © 2017 Japanese Society of Animal Science.

  1. Probing the binding of fluoxetine hydrochloride to human serum albumin by multispectroscopic techniques

    NASA Astrophysics Data System (ADS)

    Katrahalli, Umesha; Jaldappagari, Seetharamappa; Kalanur, Shankara S.

    2010-01-01

    The interaction between human serum albumin (HSA) and fluoxetine hydrochloride (FLX) have been studied by using different spectroscopic techniques viz., fluorescence, UV-vis absorption, circular dichroism and FTIR under simulated physiological conditions. Fluorescence results revealed the presence of static type of quenching mechanism in the binding of FLX to HSA. The values of binding constant, K of FLX-HSA were evaluated at 289, 300 and 310 K and were found to be 1.90 × 10 3, 1.68 × 10 3 and 1.45 × 10 3 M -1, respectively. The number of binding sites, n was noticed to be almost equal to unity thereby indicating the presence of a single class of binding site for FLX on HSA. Based on the thermodynamic parameters, Δ H0 and Δ S0 nature of binding forces operating between HSA and FLX were proposed. Spectral results revealed the conformational changes in protein upon interaction. Displacement studies indicated the site I as the main binding site for FLX on HSA. The effect of common ions on the binding of FLX to HSA was also investigated.

  2. Material and device properties of superacid-treated monolayer molybdenum disulfide

    DOE PAGES

    Alharbi, Abdullah; Zahl, Percy; Shahrjerdi, Davood

    2017-01-16

    Here, we study the effects of chemical treatment with bis(trifluoromethane) sulfonimide superacid on material and device properties of monolayer molybdenum disulfide grown by chemical vapor deposition. Our spatially resolved photoluminescence (PL) measurements and device studies reveal two key findings due to the chemical treatment: (1) noticeable transformation of trions to neutral excitons, and (2) over 7-fold reduction in the density of mid-gap trap states. Specifically, a combination of scanning Auger microscopy and PL mapping reveals that the superacid treatment is effective in passivating the sulfur-deficient regions.

  3. 77 FR 71458 - New International Mail Contract

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ... POSTAL REGULATORY COMMISSION [Docket No. CP2013-20; Order No. 1553] New International Mail Contract AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing a...\\ Id. at 5-7. \\3\\ Differences include numerous revisions to existing Articles and five new Articles. Id...

  4. A qualitative study of the prodrome to first-episode major depressive disorder in adolescents.

    PubMed

    Syed Sheriff, Rebecca J; McGorry, Patrick D; Cotton, Sue; Yung, Alison R

    2015-01-01

    Currently, we lack a clear picture of the evolution of major depressive disorder (MDD) in adolescents. The period of disturbance preceding MDD can be conceptualised as the prodrome. The aim of the study was to explore the prodrome of first-episode MDD retrospectively in a group of help-seeking adolescents using qualitative methodologies. Consecutively referred adolescents (15-18 years of age) with first-episode MDD were recruited for this study from Orygen Youth Health, Melbourne, Vic., Australia. After using quantitative methodologies to confirm the index episode of MDD and measure the extent of recovery, the prodrome was investigated in depth using qualitative techniques. Twenty-nine adolescents (20 females and 9 males) and 7 informants (6 mothers and 1 grandmother) participated. All 29 participants had a prodrome of varying lengths (between 6 days and 4 years). The most noticeable symptoms initially were perplexity and confusion and, thereafter, sadness and irritability. A common pattern was a reduction in their ability to fulfil their role accompanied by guilt, self-blame and reduced self-esteem. Around half of the participants had increased thoughts of suicide and increased anxiety. There were gender differences in the patterns of symptoms noticed, with males more commonly noticing a change in how they related to the world and females more commonly noticing a change in the way that they related to others. All informants noticed a prodrome of varying lengths; in 2 cases longer, in 2 cases shorter and in 3 cases around the same time period as that noticed by the participant. The changes most commonly noticed by informants were sadness, upset, irritability and reduced self-esteem. The symptoms were fewer in number and sometimes varied from those noticed by the adolescents themselves. Whilst we recognise that this study is vulnerable to autobiographical bias, we took all reasonable measures to minimise this. Symptoms not included in the diagnostic criteria for depression were the earliest changes noticed by the adolescents themselves and are, therefore, potentially important in informing prevention strategies, as is the finding that there are gender differences in the patterns of changes noticed. In addition, parents may provide an additional avenue to help seeking.

  5. 75 FR 8758 - New Postal Product

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... POSTAL REGULATORY COMMISSION [Docket No. CP2010-24; Order No. 410] New Postal Product AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing a recently-filed Postal... incidental differences. Id. at 6. The Postal Service contends that its filings demonstrate that this new GEPS...

  6. [Structural and Dipole Structure Peculiarities of Hoogsteen Base Pairs Formed in Complementary Nucleobases according to ab initio Quantum Mechanics Studies].

    PubMed

    Petrenko, Y M

    2015-01-01

    Ab initio quantum mechanics studies for the detection of structure and dipole structure peculiarities of Hoogsteen base pairs relative to Watson-Crick base pairs, were performed during our work. These base pairs are formed as a result of complementary interactions. It was revealed, that adenine-thymine Hoogsteen base pair and adenine-thymine Watson-Crick base pairs can be formed depending on initial configuration. Cytosine-guanine Hoogsteen pairs are formed only when cytosine was originally protonated. Both types of Hoogsteen pairs have noticeable difference in the bond distances and angles. These differences appeared in purine as well as in pyrimidine parts of the pairs. Hoogsteen pairs have mostly shorter hydrogen bond lengths and significantly larger angles of hydrogen bonds and larger angles between the hydrogen bonds than Watson-Crick base pairs. Notable differences are also observed with respect to charge distribution and dipole moment. Quantitative data on these differences are shown in our work. It is also reported that the values of local parameters (according to Cambridge classification of the parameters which determine DNA properties) in Hoogsteen base pairs, are greatly different from Watson-Crick ones.

  7. Ultastructural analysis on acetylcholinesterase localization in the cerebellar cortex of teleosts.

    PubMed

    Contestabile, A; Villani, L; Ciani, F

    1977-12-28

    The histochemical localization of acetylcholinesterase (AChE) was studied by electron microscopy in the cerebellar cortex of the goldfish and the catfish. The patterns of enzyme distribution show noticeable differences in the two teleost species at the level of the corresponding cerebellar structures. Among the most distinctive features is the prevailing intracellular localization of enzyme activity in the goldfish and the prevailing extracellular localization in the catfish in the molecular layer and, to a lesser extent, the granular layer. Only quantitative differences in the ability to synthesize AChE can be recorded among the different cerebellar neurons in the two species, since all these neurons exhibit different amounts of enzyme activity linked to their cytoplasmic structures. Comparing the results obtained with those of previous histochemical, experimental and developmental researches, the hypothesis seems well founded that the embryonic pool of cerebellar neurons is made up of AChE-synthesizing nruroblasts which, during development, loss or maintain to a different the mechanisms for AChE synthesis. In addition the light and electron microscope histochemistry reveals at different levels of resolution that the final pattern of AChE distribution in the cerebellar cortex is the sum of different degress of AChE synthesis by cerebellar neurons and different degrees of enzyme release in extracellular spaces.

  8. 48 CFR 30.605 - Processing noncompliances.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... with the alleged noncompliance; or (ii) Issue a notice of potential noncompliance to the contractor and provide a copy to the auditor. (2) The notice of potential noncompliance shall— (i) Notify the contractor... difference is increased cost to the Government. (ii) When the negotiated contract or subcontract price is...

  9. 48 CFR 30.605 - Processing noncompliances.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... with the alleged noncompliance; or (ii) Issue a notice of potential noncompliance to the contractor and provide a copy to the auditor. (2) The notice of potential noncompliance shall— (i) Notify the contractor... difference is increased cost to the Government. (ii) When the negotiated contract or subcontract price is...

  10. 48 CFR 30.605 - Processing noncompliances.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... with the alleged noncompliance; or (ii) Issue a notice of potential noncompliance to the contractor and provide a copy to the auditor. (2) The notice of potential noncompliance shall— (i) Notify the contractor... difference is increased cost to the Government. (ii) When the negotiated contract or subcontract price is...

  11. 48 CFR 30.605 - Processing noncompliances.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... with the alleged noncompliance; or (ii) Issue a notice of potential noncompliance to the contractor and provide a copy to the auditor. (2) The notice of potential noncompliance shall— (i) Notify the contractor... difference is increased cost to the Government. (ii) When the negotiated contract or subcontract price is...

  12. 48 CFR 30.605 - Processing noncompliances.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... with the alleged noncompliance; or (ii) Issue a notice of potential noncompliance to the contractor and provide a copy to the auditor. (2) The notice of potential noncompliance shall— (i) Notify the contractor... difference is increased cost to the Government. (ii) When the negotiated contract or subcontract price is...

  13. 77 FR 21586 - II-VI, Incorporated, Infrared Optics-Saxonburg Division, Saxonburg, PA; Notice of Affirmative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ...). The workers were engaged in employment related to the production of infrared and CO 2 laser optics... 2 laser optics, and related materials, from 2009 to 2010 or from January- October 2010 compared to... investigation revealed that the workers' firm did not shift production of infrared and CO 2 laser optics, and...

  14. 76 FR 35026 - Weather Shield Manufacturing, Inc. Corporate Office, Medford, WI; Notice of Amended Negative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-15

    ... subject firm's major declining customers regarding their purchases of doors and/or windows in the relevant period. AAR 29-48. The survey revealed that customer imports of articles like or directly competitive... customer list or any list of the customers to whom Labor issued questionnaires.'') The materials to which...

  15. The Older Worker. Statistical Reports on Older Americans, No. 6.

    ERIC Educational Resources Information Center

    Chan, Teresita; Fowles, Donald G.

    Trends in the labor force participation and unemployment of older workers were reviewed in a study. A declining rate of labor force participation by older men and a growth in participation by older women were noticed. Examination of labor force participation rates by race revealed a higher participation rate for minority women than for older white…

  16. 76 FR 5831 - Amdocs, Inc., Global Support Services, Advertising And Media AT&T Division, New Haven...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-02

    ... Support Services, Advertising And Media AT&T Division, New Haven, Connecticut; Notice of Affirmative... workers and former workers of Amdocs, Inc., Global Support Services, Advertising and Media AT&T Division..., Advertising and Media AT&T Division. The investigation also revealed that the firm is not a Supplier or...

  17. Everything You Want To Know about Attachment.

    ERIC Educational Resources Information Center

    Honig, Alice Sterling

    This paper discusses infant attachment, which it defines as a long-lasting emotional bond revealed when a child under stress seeks out and tries to stay close to a specific figure. The paper addresses: (1) What is attachment? Who are the pioneers in attachment theory?; (2) How do we notice attachment in action?; (3) Is attachment the only…

  18. Electromagnetic exploration of the oceanic mantle

    PubMed Central

    UTADA, Hisashi

    2015-01-01

    Electromagnetic exploration is a geophysical method for examining the Earth’s interior through observations of natural or artificial electromagnetic field fluctuations. The method has been in practice for more than 70 years, and 40 years ago it was first applied to ocean areas. During the past few decades, there has been noticeable progress in the methods of instrumentation, data acquisition (observation), data processing and inversion. Due to this progress, applications of this method to oceanic regions have revealed electrical features of the oceanic upper mantle down to depths of several hundred kilometers for different geologic and tectonic environments such as areas around mid-oceanic ridges, areas around hot-spot volcanoes, subduction zones, and normal ocean areas between mid-oceanic ridges and subduction zones. All these results estimate the distribution of the electrical conductivity in the oceanic mantle, which is key for understanding the dynamics and evolution of the Earth together with different physical properties obtained through other geophysical methods such as seismological techniques. PMID:26062736

  19. IPS Empress inlays luted with a self-adhesive resin cement after 1 year.

    PubMed

    Taschner, Michael; Frankenberger, Roland; García-Godoy, Franklin; Rosenbusch, Silke; Petschelt, Anselm; Krämer, Norbert

    2009-02-01

    To prospectively compare the clinical performance of two different resin composites for luting IPS Empress inlays and onlays. 83 IPS Empress restorations were placed in 30 subjects. All restorations were inserted under rubber dam. 43 inlays/onlays were luted with a self-adhesive resin cement [RelyX Unicem (RX)]. A multistep adhesive (Syntac) was used with Variolink II low viscosity (SV) and served as control (n=40). The restorations were evaluated after 2 weeks: Baseline = 1st recall (R1), after 6 months (R2) and after 1 year (R3) by two calibrated examiners using the modified USPHS criteria. From R1 to R3, one failure was noticed in the SV group (R2) due to marginal enamel chipping. After 1 year of clinical service, SV revealed significantly better results regarding color match and integrity inlay (Mann-Whitney U-test, P< 0.05). No statistically significant differences were observed between SV and RX for the remaining criteria (Mann-Whitney U-test, P>0.05).

  20. Molecular Features of Dissolved Organic Matter Produced by Picophytoplankton

    NASA Astrophysics Data System (ADS)

    Ma, X.; Coleman, M.; Waldbauer, J.

    2016-02-01

    Compounds derived from picophytoplankton through exudation, grazing and viral lysis contribute a large proportion of labile DOM to the ocean. This labile DOM is rapidly turned over by and exchanged among microbial communities. However, identifying labile DOM compounds and tracking their sources and sinks in ocean ecosystems is complicated by the presence of non-labile DOM which has a significantly larger reservoir size and longer residence time. This study focuses on investigating labile DOM produced by single-strain cyanobacteria isolates via different modes of release and varied nutrient conditions. DOM compounds are analyzed by high-resolution mass spectrometry. Statistical comparison between intracellular and extracellular molecular data of Synechococcus WH7803 revealed noticeable differences in terms of compound number, size and structure. Incubation experiments using combined whole seawater and diluent of grazer-free or viral-free water at the BATS time-series station in Sargasso Sea yielded complimentary data to be synthesized with data from lab cultures. The compositional features of each type of DOM could serve as future proxies for different modes of DOM production in the oceans.

  1. Application of remote sensing data to structural analysis of the East Kalimantan, Indonesia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moriya, Shunji; Nishidai, Takashi

    1996-07-01

    JERS-1 SAR and LANDSAT TM images of the northern Kutei Basin, East Kalimantan, Indonesia were geologically interpreted. The focus of the study is on the structural analysis of the Samarinda Anticlinorium located in the onshore area of the Kutei Basin. In the Samarinda Anticlinorium, N-S folds and thrusts are well developed in the Tertiary sediments. They are believed to have been formed during the Middle Miocene or later. In addition to the N-S structure, an extensive NW-SE lineament traversing the central part of the study area can be identified on the images. Image interpretation reveals that this lineament is amore » major fault formed before the Oligocene. Noticeable differences in the N-S structure are recognized at the north and south of this NW-SE fault, Lithology and thickness of the sediments overlying the basement are remarkably different at the north and south of the fault. These may be responsible for the differences in the N-S structure of the northern and southern Anticlinorium.« less

  2. Force field-dependent structural divergence revealed during long time simulations of Calbindin d9k.

    PubMed

    Project, Elad; Nachliel, Esther; Gutman, Menachem

    2010-07-15

    The structural and the dynamic features of the Calbindin (CaB) protein in its holo and apo states are compared using molecular dynamics simulations under nine different force fields (FFs) (G43a1, G53a6, Opls-AA, Amber94, Amber99, Amber99p, AmberGS, AmberGSs, and Amber99sb). The results show that most FFs reproduce reasonably well the majority of the experimentally derived features of the CaB protein. However, in several cases, there are significant differences in secondary structure properties, root mean square deviations (RMSDs), root mean square fluctuations (RMSFs), and S(2) order parameters among the various FFs. What is more, in certain cases, these parameters differed from the experimentally derived values. Some of these deviations became noticeable only after 50 ns. A comparison with experimental data indicates that, for CaB, the Amber94 shows overall best agreement with the measured values, whereas several others seem to deviate from both crystal and nuclear magnetic resonance data. Copyright 2009 Wiley Periodicals, Inc.

  3. Modification of Optical, Structural and Dielectric Properties of MeV Ions Irradiated PS/Cu Nanocomposites.

    PubMed

    Gavade, Chaitali; Singh, N L; Khanna, P K; Shah, Sunil

    2015-12-01

    In order to study structural, thermal, optical and dielectric behaviors of composites, the films of Cu/polystyrene nanocomposites were synthesized at different concentrations of Cu-nanoparticles. These polymer nanocomposites were irradiated with carbon (85 MeV) and silicon (120 MeV) ions at different fluences. The samples were characterized using different techniques viz: X-ray diffraction, UV-visible spectroscopy, differential scanning calorimetry, and impedance gain phase analyzer. A noticeable increase in the intensity of X-ray diffraction peaks was observed after irradiation with 120 MeV Si-ions, which may be attributed to radiation-induced cross-linking in polymer. Optical properties like band gap was estimated for pure polymer and nanocomposite films from their optical absorption spectra in the wavelength region 200-800 nm. It was found that the band gap value shifted to lower energy (from 4.38 eV to 3.40 eV) on doping with silver nanoparticles and also upon irradiation. Differential scanning calorimetry analysis revealed an increase in the glass transition temperature upon irradiation, which may be attributed to cross linking of polymer chain due to ion beam irradiation which is also corroborated with XRD analysis. Dependence of dielectric properties on frequency, ions and filler concentration was studied. The results revealed the enhancement in dielectric properties after doping nanoparticles and also upon irradiation. It was observed that the effect of Si-beam is more effectual than the C-beam because of large electronic energy loss of heavy ion.

  4. 78 FR 13897 - Final Revision and Publication of the 2012 Form M-1, Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-01

    ... DEPARTMENT OF LABOR Employee Benefits Security Administration RIN 1210-AB51 Final Revision and Publication of the 2012 Form M-1, Notice AGENCY: Employee Benefits Security Administration, Department of... Security Administration's (EBSA) Web site at www.dol.gov/ebsa . The revised form is substantively different...

  5. 75 FR 17175 - New Postal Product

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... POSTAL REGULATORY COMMISSION [Docket Nos. CP2010-33, CP2010-34 and CP2010-35; Order No. 431] New Postal Product AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing... differences. Id. at 6. The Postal Service contends that its filings demonstrate that each of the new GEPS 2...

  6. SU-E-T-301: Dosimetric Comparison Between Adaptive and Rectilinear Template-Based Prostate Seed Implants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sugar, E Neubauer; Buzurovic, I; O’Farrell, D

    2015-06-15

    Purpose: To compare the dosimetry of a standard rectilinear and an adaptive technique used in I125 prostate seed implants. Methods: To achieve favorable dosimetry in prostate implants we used adaptive needle updates to match actual positions in real-time. The seed locations were optimized based on actual needle locations. The seeds were delivered automatically with a robotic device seedSelectron™ (Elekta Brachytherapy). In this study, we evaluated the former approach against the standard rectilinear technique in which the needles have a parallel distribution. The treatment plans for 10 patients were analyzed. For comparison, the actual treatment plans were revised so each needlemore » was repositioned to its original parallel location through the template. The analysis was performed by comparing the target coverage and dose to the organs at risk. The comparison was done using the following planning goals: the target D90> 90%, V100% > 90%, V50% <70% and V200% <30%; the urethra V125% < 1cm3 and V150%= 0cm3; and the Rectum V100%<1cm3 and V69% < 8cm3. The prescription dose to the target was 145Gy. Results: The average target volume and number of seeds were 44.39cm3(SD=11.14) and 74(SD=12), respectively. The D90 for adaptive and rectilinear plans was 159.9Gy(SD=2.99) and 155.53Gy(SD=4.04) resulting in a 2.74% difference for the average target coverage. A similar difference (1.75%) was noticed in the target V100[%]. No significant difference was noticed in the dose to the urethra and rectum. All planning goals were met with both the adaptive and rectilinear approach for each plan. Conclusion: The study reveals enhanced coverage of the target when using the adaptive needle adjustments as compared to the rectilinear approach for the analyzed cases. However, the differences in dosimetry did not translate to meaningful clinical outcomes.« less

  7. Effect of Te inclusions in CdZnTe crystals at different temperatures

    NASA Astrophysics Data System (ADS)

    Hossain, A.; Bolotnikov, A. E.; Camarda, G. S.; Gul, R.; Kim, K.-H.; Cui, Y.; Yang, G.; Xu, L.; James, R. B.

    2011-02-01

    CdZnTe crystals often exhibit nonuniformities due to the presence of Te inclusions and dislocations. High concentrations of such defects in these crystals generally entail severe charge-trapping, a major problem in ensuring the device's satisfactory performance. In this study, we employed a high-intensity, high-spatial-resolution synchrotron x-ray beam as the ideal tool to generate charges by focusing it over the large Te inclusions, and then observing the carrier's response at room- and at low-temperatures. A high spatial 5-μm resolution raster scan revealed the fine details of the presence of extended defects, like Te inclusions and dislocations in the CdZnTe crystals. A noticeable change was observed in the efficiency of electron charge collection at low temperature (1 °C), but it was hardly altered at room-temperature.

  8. [The problem of comorbidity of phobic disorders in adolescents].

    PubMed

    Golovina, A G

    2007-01-01

    Age peculiarities of the comorbidity of the phobic syndrome with other psychopathological formations have been studied on the basis of clinical and follow-up examination of 314 patients, 257 male, 57 female, aged 15-17 years old, with phobic disorders diagnosed according to ICD-10 criteria. Simple phobias found in 21% of patients existed as an isolated phenomenon displaying no comorbidity. Asthenic syndrome was most frequently concomitant with phobias (293 patients); personality anomalies were found in 167 patients including 31 with personality disorders; affective syndrome was observed in 61 patients and other ones were noticeably rare. Within the structure of the acute states, phobias appear as a schizophrenic attack or reactive symptoms correlating with the basic syndrome by the time of onset, intensity and content. Age differences of the phobic and related psychopathological syndromes are revealed.

  9. Comparative study of eddy current and Barkhausen noise nondestructive testing methods in microstructural examination of ferrite-martensite dual-phase steel

    NASA Astrophysics Data System (ADS)

    Ghanei, S.; Kashefi, M.; Mazinani, M.

    2014-04-01

    The magnetic properties of ferrite-martensite dual-phase steels were evaluated using eddy current and Barkhausen noise nondestructive testing methods and correlated with their microstructural changes. Several routes were used to produce different microstructures of dual-phase steels. The first route was different heat treatments in γ region to vary the ferrite grain size (from 9.47 to 11.12 in ASTM number), and the second one was variation in intercritical annealing temperatures (from 750 to 890 °C) in order to produce different percentages of martensite in dual-phase microstructure. The results concerning magnetic Barkhausen noise are discussed in terms of height, position and shape of Barkhausen noise profiles, taking into account two main aspects: ferrite grain size, and different percentages of martensite. Then, eddy current testing was used to study the mentioned microstructural changes by detection of impedance variations. The obtained results show that microstructural changes have a noticeable effect on the magnetic properties of dual-phase steels. The results reveal that both magnetic methods have a high potential to be used as a reliable nondestructive tool to detect and monitor microstructural changes occurring during manufacturing of dual-phase steels.

  10. Contributions of available substrates and activities of trophic microbial community to methanogenesis in vegetative and reproductive rice rhizospheric soil.

    PubMed

    Chawanakul, Sansanee; Chaiprasert, Pawinee; Towprayoon, Sirintornthep; Tanticharoen, Morakot

    2009-01-01

    Potential of methane production and trophic microbial activities at rhizospheric soil during rice cv. Supanbunri 1 cultivation were determined by laboratory anaerobic diluents vials. The methane production was higher from rhizospheric than non-rhizospheric soil, with the noticeable peaks during reproductive phase (RP) than vegetative phase (VP). Glucose, ethanol and acetate were the dominant available substrates found in rhizospheric soil during methane production at both phases. The predominance activities of trophic microbial consortium in methanogenesis, namely fermentative bacteria (FB), acetogenic bacteria (AGB), acetate utilizing bacteria (AB) and acetoclastic methanogens (AM) were also determined. At RP, these microbial groups were enhanced in the higher of methane production than VP. This correlates with our finding that methane production was greater at the rhizospheric soil with the noticeable peaks during RP (1,150 +/- 60 nmol g dw(-1) d(-1)) compared with VP (510 +/- 30 nmol g dw(-1) d(-1)). The high number of AM showed the abundant (1.1x10(4) cell g dw(-1)) with its high activity at RP, compared to the less activity with AM number at VP (9.8x10(2) cell g dw(-1)). Levels of AM are low in the total microbial population, being less than 1% of AB. These evidences revealed that the microbial consortium of these two phases were different.

  11. 14 CFR 11.7 - What is a supplemental notice of proposed rulemaking?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... rulemaking? 11.7 Section 11.7 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... information on an issue, or that we should take a different approach than we proposed. Also, we may want to..., FAA may issue a supplemental notice of proposed rulemaking (SNPRM) to give the public an opportunity...

  12. 14 CFR 11.7 - What is a supplemental notice of proposed rulemaking?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... rulemaking? 11.7 Section 11.7 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... information on an issue, or that we should take a different approach than we proposed. Also, we may want to..., FAA may issue a supplemental notice of proposed rulemaking (SNPRM) to give the public an opportunity...

  13. 14 CFR 11.7 - What is a supplemental notice of proposed rulemaking?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... rulemaking? 11.7 Section 11.7 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... information on an issue, or that we should take a different approach than we proposed. Also, we may want to..., FAA may issue a supplemental notice of proposed rulemaking (SNPRM) to give the public an opportunity...

  14. 14 CFR 11.7 - What is a supplemental notice of proposed rulemaking?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... rulemaking? 11.7 Section 11.7 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... information on an issue, or that we should take a different approach than we proposed. Also, we may want to..., FAA may issue a supplemental notice of proposed rulemaking (SNPRM) to give the public an opportunity...

  15. 14 CFR 11.7 - What is a supplemental notice of proposed rulemaking?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... rulemaking? 11.7 Section 11.7 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... information on an issue, or that we should take a different approach than we proposed. Also, we may want to..., FAA may issue a supplemental notice of proposed rulemaking (SNPRM) to give the public an opportunity...

  16. 36 CFR 228.4 - Plan of operations-notice of intent-requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... used and maintained for National Forest System purposes; (ii) Prospecting and sampling which will not... disturbance which is substantially different than that caused by other users of the National Forest System who... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Plan of operations-notice of...

  17. Finding versus Fixing: Self-Monitoring for Readers Who Struggle

    ERIC Educational Resources Information Center

    Anderson, Nancy L.; Kaye, Elizabeth L.

    2017-01-01

    This article explains how teachers can understand, notice, and supportively respond to readers who struggle with self-monitoring during text reading. The unique strategic processing demands for readers who struggle support the argument that teaching children to find and notice errors is different than fixing a word, or getting it right. Three…

  18. 78 FR 23611 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... simultaneously trade different asset classes within the same strategy. Because cash equities and options markets...-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate Effectiveness of a... April 1, 2013, The NASDAQ Stock Market LLC (``NASDAQ'' or ``Exchange'') filed with the Securities and...

  19. 77 FR 15163 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-14

    ... troubling trend of reduced participation in the equity markets by individual investors, and that nearly 30... different asset classes within a single strategy. NASDAQ also notes that cash equities and options markets...-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate Effectiveness of...

  20. 78 FR 36211 - Extension of Employment Authorization for Syrian F-1 Nonimmigrant Students Experiencing Severe...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-17

    ... graduate students, as well as elementary school, middle school, and high school students. The notice, however, applies differently to elementary school, middle school, and high school students (see the... school, and high school students in F-1 status?''). F-1 students covered by this notice who transfer to...

  1. 77 FR 75487 - Self-Regulatory Organizations; The Options Clearing Corporation; Notice of No Objection to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-20

    ... of the Dodd-Frank Wall Street Reform and Consumer Protection Act (``Dodd-Frank Act''),\\1\\ entitled... proposed rule change discussed in the advance notice. \\1\\ Dodd-Frank Wall Street Reform and Consumer..., the Commission approval order notes that OCC retains discretion to employ different confidence levels...

  2. Microstructure and Mechanical Properties of Additively Manufactured Parts with Staircase Feature

    NASA Astrophysics Data System (ADS)

    Keya, Tahmina

    This thesis focuses on a part with staircase feature that is made of Inconel 718 and fabricated by SLM process. The objective of the study was to observe build height effect on the microstructure and mechanical properties of the part. Due to the nature of SLM, there is possibility of different microstructure and mechanical properties in different locations depending on the design of the part. The objective was to compare microstructure and mechanical properties from different location and four comparison groups were considered: 1. Effect of thermal cycle; 2. External and internal surfaces; 3. Build height effect and 4. Bottom surfaces. To achieve the goals of this research, standard metallurgical procedure has been performed to prepare samples. Etching was done to reveal the microstructure of SLM processed Inconel 718 parts. Young's modulus and hardness were measured using nanoindentation technique. FEM analysis was performed to simulate nanoindentation. The conclusions drawn from this research are: 1. The microstructure of front and side surface of SLM processed Inconel 718 consists of arc shaped cut ends of melt pools with intermetallic phase at the border of the melt pool; 2. On top surface, melted tracks and scanning patterns can be observed and the average width of melted tracks is 100-150 microm; 3. The microstructure looks similar at different build height; 4. Microstructure on the top of a stair is more defined and organized than the internal surface; 5. The mechanical properties are highest at the bottom. OM images revealed slight difference in microstructure in terms of build height for this specific part, but mechanical properties seem to be vary noticeably. This is something to be kept in mind while designing or determining build orientation. External and internal surfaces of a stair at the same height showed difference in both microstructure and mechanical properties. To minimize that effect and to make it more uniform, gradual elevation can be considered when suitable as far as design modification is concerned. Above all, this study reveals important information about the pattern of microstructure, thus heat transfer mechanism inside a part which is useful to understand the SLM process.

  3. Ready or not: analysis of a no-notice mass vaccination field response in Philadelphia.

    PubMed

    Caum, Jessica; Alles, Steven

    2013-12-01

    Local health departments typically rely on exercises to test preparedness capacity; however, pre-scripted drills often lack the sense of urgency that a real event would engender. No-notice, unscripted exercises that challenge staff to think critically under pressure may provide a mechanism for a more realistic assessment of preparedness capacity. The very active influenza season of 2012-13 presented the Public Health Preparedness Program at the Philadelphia Department of Public Health with the opportunity to conduct an influenza vaccination clinic at a local boarding school. Program leaders used this opportunity to design a no-notice exercise to test the ability of staff to effectively coordinate an emergency field response while simultaneously delivering a real public health intervention. On the day of the exercise, staff members were given 6 hours to plan and execute a vaccination clinic without any guidance from program leaders. Best practices observed during the exercise included: (1) early identification and mitigation of rate-limiting steps, and (2) successful implementation of a previously untested high-throughput vaccination model. Although the primary intent of the exercise was to assess the ability of staff to respond to a no-notice event, this vaccination clinic also functioned as a microcosm of a larger response, revealing several considerations related to vaccine ordering, staff resources, and throughput rates that have broader implications for public health responses to large-scale biological attacks or pandemics.

  4. Self-inflicted fatal shotgun wound from a homemade weapon.

    PubMed

    Tsuboi, Akio; Satoh, Fumiko; Seto, Yoshihisa; Osawa, Motoki

    2014-03-01

    A case of suicide, a male shot in the abdomen using a homemade weapon, is described herein. Postmortem examination revealed bleeding into the thoracic and abdominal cavities, a collapsed liver and other organs with numerous pellets. The contact-shot wound was not noticed during the initial investigation at the scene, but it was elucidated during autopsy. A simple launcher had been assembled from pipes of a clothes rack frame made for home use. The deceased had once owned a shotgun, but his firearm license had been relinquished 5 years prior. A shotgun shell that he had kept was used. Presumably, the injuries from the homemade weapon were not noticed initially because of strict gun control rules in Japan. Crown Copyright © 2013. Published by Elsevier Ireland Ltd. All rights reserved.

  5. The influence of attention on mathematical knowledge of teachers and lecturers: a comparison

    NASA Astrophysics Data System (ADS)

    Klymchuk, Sergiy; Thomas, Michael O. J.

    2011-10-01

    This article reports on some findings from the project 'Analysing the Transition from Secondary to Tertiary Education in Mathematics'. One of the key variables in the school to university transition is the teacher/lecturer, and here, we deal with the data analysing secondary teachers' and tertiary lecturers' responses to four mathematics questions. Elsewhere, we consider knowledge, preparedness, teaching style, etc., but this article tracks the ability to use mathematical procedures. We hypothesize that this is a function of what we pay attention to, as described in Mason's discipline of noticing. The results reveal that many teachers and lecturers fail to notice the necessary conditions for problems that imply that procedures are not always applicable. Possible reasons for this along with implications for student learning are discussed.

  6. Modelling of human low frequency sound localization acuity demonstrates dominance of spatial variation of interaural time difference and suggests uniform just-noticeable differences in interaural time difference.

    PubMed

    Smith, Rosanna C G; Price, Stephen R

    2014-01-01

    Sound source localization is critical to animal survival and for identification of auditory objects. We investigated the acuity with which humans localize low frequency, pure tone sounds using timing differences between the ears. These small differences in time, known as interaural time differences or ITDs, are identified in a manner that allows localization acuity of around 1° at the midline. Acuity, a relative measure of localization ability, displays a non-linear variation as sound sources are positioned more laterally. All species studied localize sounds best at the midline and progressively worse as the sound is located out towards the side. To understand why sound localization displays this variation with azimuthal angle, we took a first-principles, systemic, analytical approach to model localization acuity. We calculated how ITDs vary with sound frequency, head size and sound source location for humans. This allowed us to model ITD variation for previously published experimental acuity data and determine the distribution of just-noticeable differences in ITD. Our results suggest that the best-fit model is one whereby just-noticeable differences in ITDs are identified with uniform or close to uniform sensitivity across the physiological range. We discuss how our results have several implications for neural ITD processing in different species as well as development of the auditory system.

  7. Comparative study on gastrointestinal microbiota of eight fish species with different feeding habits.

    PubMed

    Li, J; Ni, J; Li, J; Wang, C; Li, X; Wu, S; Zhang, T; Yu, Y; Yan, Q

    2014-12-01

    To reveal the effects of fish genotype, feeding habits and serum physiological index on the composition of gastrointestinal microbiota, eight fish species with four different feeding habits were investigated. The V1 to V3 regions of 16S rRNA gene were analysed by high-throughput sequencing (454 platform) to compare the gut microbiota of different fish species. A total of 551 995 high-quality sequences with an average length of 463 bp were obtained from the 48 samples. No significant difference was observed among the detected sequences obtained from fishes with different feeding habits (One-way anova, F = 1·003, P = 0·400), but the number of OTUs among different feeding habits was significantly different (One-way anova, F = 7·564, P < 0·001). Additionally, significant correlations were detected between the fish genotype and microbial composition (partial Mantel test, all P values = 0·001) in the stomach, foregut and hindgut. Moreover, different core intestinal microbiota was also noticed in the eight fish species with different feeding habits. Feeding habits and genotype clearly affected the gastrointestinal microbiota of fish. Moreover, the evolutionary process shaped the serum physiological indexes of fish. This study provided much important information for developing commercial fish feeds. © 2014 The Society for Applied Microbiology.

  8. An XRPD and EPR spectroscopy study of microcrystalline calcite bioprecipitated by Bacillus subtilis

    NASA Astrophysics Data System (ADS)

    Perito, B.; Romanelli, M.; Buccianti, A.; Passaponti, M.; Montegrossi, G.; Di Benedetto, F.

    2018-05-01

    We report in this study the first XRPD and EPR spectroscopy characterisation of a biogenic calcite, obtained from the activity of the bacterium Bacillus subtilis. Microcrystalline calcite powders obtained from bacterial culture in a suitable precipitation liquid medium were analysed without further manipulation. Both techniques reveal unusual parameters, closely related to the biological source of the mineral, i.e., to the bioprecipitation process and in particular to the organic matrix observed inside calcite. In detail, XRPD analysis revealed that bacterial calcite has slightly higher c/a lattice parameters ratio than abiotic calcite. This correlation was already noticed in microcrystalline calcite samples grown by bio-mineralisation processes, but it had never been previously verified for bacterial biocalcites. EPR spectroscopy evidenced an anomalously large value of W 6, a parameter that can be linked to occupation by different chemical species in the next nearest neighbouring sites. This parameter allows to clearly distinguish bacterial and abiotic calcite. This latter achievement was obtained after having reduced the parameters space into an unbiased Euclidean one, through an isometric log-ratio transformation. We conclude that this approach enables the coupled use of XRPD and EPR for identifying the traces of bacterial activity in fossil carbonate deposits.

  9. Contact leukomelanosis induced by the leaves of Piper betle L. (Piperaceae): a clinical and histopathologic survey.

    PubMed

    Liao, Y L; Chiang, Y C; Tsai, T F; Lee, R F; Chan, Y C; Hsiao, C H

    1999-04-01

    In April 1997, an unusual pigmentary disorder was noticed by dermatologists in Taiwan. All patients had a history of using facial dressings with steamed leaves of Piper betle L. (Piperaceae). Our purpose was to clarify the evolution and the origin of this unique leukomelanosis. Fifteen patients with an unusual pigmentary disorder, who visited our clinic in September and October 1997, were asked to complete a questionnaire designed to elicit the history related to the disorder. Eight of these 15 patients underwent skin biopsies: 6 on the mottled hyperpigmented area (group A) and 2 on the hypopigmented area (group B). All 8 specimens were prepared with hematoxylin-eosin, Masson-Fontana, and S-100 stains. The results of the questionnaire revealed that these patients had all experienced a temporary erythematous reaction in the first few days of the use of the facial dressing, and 9 of them also complained of an accompanying stinging sensation. A bleaching effect became noticeable approximately 1 week to 1 month later. Eight patients reported that the hyperpigmentation and confetti-like hypopigmentation occurred after overexposure to the sun. In both groups, histopathologic examination revealed some melanophages in the dermis. Masson-Fontana staining of specimens from group A showed local interspersed depigmentation and hyperpigmentation in the basal epidermis and pigmentary incontinence in the dermis. This picture was different from the homogeneous depigmentation within basal epidermis in specimens from group B. In both groups, S-100 staining was negative for melanocytes in the depigmented area. The clinical course and histopathologic findings suggest that the evolution of this pigmentary disorder can be divided into 3 stages. The first stage is the immediate bleaching stage, when an irritant reaction is usually conspicuous. The second stage consists of prominent hyperpigmentation visible both grossly and microscopically. The final stage is characterized by confetti-like depigmentation. It may be induced by chemicals in the betel leaves such as phenol, catechol, and benzene derivatives, perhaps through inhibition of melanin synthesis or melanocytotoxicity.

  10. 77 FR 72904 - U.S. Department of State Advisory Committee on Private International Law (ACPIL): Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ... DEPARTMENT OF STATE [Public Notice 8106] U.S. Department of State Advisory Committee on Private... Court Agreements The Office of the Assistant Legal Adviser for Private International Law, Department of... participants prior to the meeting. The new version differs from earlier draft texts in two key respects: (1...

  11. 29 CFR 4245.6 - Contents of notice of insolvency benefit level.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (a)(7) to (a)(10) need be submitted only if it is different from the information submitted to the PBGC with the notice of insolvency filed for that insolvency year (see § 4245.4 (a)(7) to (a)(10)) or... insolvency year. (10) The estimated amount of the plan's available resources for the insolvency year. (11...

  12. 29 CFR 4245.6 - Contents of notice of insolvency benefit level.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (a)(7) to (a)(10) need be submitted only if it is different from the information submitted to the PBGC with the notice of insolvency filed for that insolvency year (see § 4245.4 (a)(7) to (a)(10)) or... insolvency year. (10) The estimated amount of the plan's available resources for the insolvency year. (11...

  13. The Effects of Communication Mode on Negotiation of Meaning and Its Noticing

    ERIC Educational Resources Information Center

    Yuksel, Dogan; Inan, Banu

    2014-01-01

    This study examined the effects of communication mode ("i.e.", face to face versus computer mediated communication) on the instances of negotiation of meaning (NofM) and its level of noticing by learners. Sixty-four participants (32 dyads) completed two jigsaw tasks in two different mediums (one in each) and four days after the tasks…

  14. 76 FR 30937 - Small Hydropower Development in the United States; Notice of Small/Low-Impact Hydropower Webinar

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ... Development in the United States; Notice of Small/Low-Impact Hydropower Webinar The Federal Energy Regulatory... projects. Specifically, the webinar will provide the opportunity for participants to learn the differences..., learn how to get more information and assistance from FERC staff, and ask questions. To register for...

  15. Subcellular proteome profiles of different latex fractions revealed washed solutions from rubber particles contain crucial enzymes for natural rubber biosynthesis.

    PubMed

    Wang, Dan; Sun, Yong; Chang, Lili; Tong, Zheng; Xie, Quanliang; Jin, Xiang; Zhu, Liping; He, Peng; Li, Hongbin; Wang, Xuchu

    2018-06-30

    Rubber particle (RP) is a specific organelle for natural rubber biosynthesis (NRB) and storage in rubber tree Hevea brasiliensis. NRB is processed by RP membrane-localized proteins, which were traditionally purified by repeated washing. However, we noticed many proteins in the discarded washing solutions (WS) from RP. Here, we compared the proteome profiles of WS, C-serum (CS) and RP by 2-DE, and identified 233 abundant proteins from WS by mass spectrometry. Many spots on 2-DE gels were identified as different protein species. We further performed shotgun analysis of CS, WS and RP and identified 1837, 1799 and 1020 unique proteins, respectively. Together with 2-DE, we finally identified 1825 proteins from WS, 246 were WS-specific. These WS-specific proteins were annotated in Gene Ontology, indicating most abundant pathways are organic substance metabolic process, protein degradation, primary metabolic process, and energy metabolism. Protein-protein interaction analysis revealed these WS-specific proteins are mainly involved in ribosomal metabolism, proteasome system, vacuolar protein sorting and endocytosis. Label free and Western blotting revealed many WS-specific proteins and protein complexes are crucial for NRB initiation. These findings not only deepen our understanding of WS proteome, but also provide new evidences on the roles of RP membrane proteins in NRB. Natural rubber is stored in rubber particle from the rubber tree. Rubber particles were traditionally purified by repeated washing, but many proteins were identified from the washing solutions (WS). We obtained the first visualization proteome profiles with 1825 proteins from WS, including 246 WS-specific ones. These WS proteins contain almost all enzymes for polyisoprene initiation and may play important roles in rubber biosynthesis. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Bilateral Cricoarytenoid Arthritis: A Cause of Recurrent Upper Airway Obstruction in Rheumatoid Arthritis

    PubMed Central

    Pradhan, Pradeep; Bhardwaj, Abhishek; Venkatachalam, VP

    2016-01-01

    We report a case of bilateral cricoarytenoid joint arthritis with history of rheumatoid arthritis, presented with stridor to the outpatient department. Endolaryngoscopy revealed adducted vocal cords and a nodule over left arytenoid which later confirmed to be rheumatoid nodule on histopathologic examination. Initially, although patient responded well to medical treatment, recurrence was noticed after 6 months follow-up. PMID:27418875

  17. 77 FR 28570 - Pure Magnesium From the People's Republic of China: Notice of Court Decision Not in Harmony With...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-15

    ... Department granted TMI's request for two by-product offsets, and calculated a dumping margin for TMI of 0.63... review. At verification, TMI's producer revealed that there were no by-product sales prior to April 2007... instructed to: (1) Further explain the valuation of TMI's by-product offsets; and (2) further explain the...

  18. Matter-wave dark solitons: stochastic versus analytical results.

    PubMed

    Cockburn, S P; Nistazakis, H E; Horikis, T P; Kevrekidis, P G; Proukakis, N P; Frantzeskakis, D J

    2010-04-30

    The dynamics of dark matter-wave solitons in elongated atomic condensates are discussed at finite temperatures. Simulations with the stochastic Gross-Pitaevskii equation reveal a noticeable, experimentally observable spread in individual soliton trajectories, attributed to inherent fluctuations in both phase and density of the underlying medium. Averaging over a number of such trajectories (as done in experiments) washes out such background fluctuations, revealing a well-defined temperature-dependent temporal growth in the oscillation amplitude. The average soliton dynamics is well captured by the simpler dissipative Gross-Pitaevskii equation, both numerically and via an analytically derived equation for the soliton center based on perturbation theory for dark solitons.

  19. Building v/s Exploring Models: Comparing Learning of Evolutionary Processes through Agent-based Modeling

    NASA Astrophysics Data System (ADS)

    Wagh, Aditi

    Two strands of work motivate the three studies in this dissertation. Evolutionary change can be viewed as a computational complex system in which a small set of rules operating at the individual level result in different population level outcomes under different conditions. Extensive research has documented students' difficulties with learning about evolutionary change (Rosengren et al., 2012), particularly in terms of levels slippage (Wilensky & Resnick, 1999). Second, though building and using computational models is becoming increasingly common in K-12 science education, we know little about how these two modalities compare. This dissertation adopts agent-based modeling as a representational system to compare these modalities in the conceptual context of micro-evolutionary processes. Drawing on interviews, Study 1 examines middle-school students' productive ways of reasoning about micro-evolutionary processes to find that the specific framing of traits plays a key role in whether slippage explanations are cued. Study 2, which was conducted in 2 schools with about 150 students, forms the crux of the dissertation. It compares learning processes and outcomes when students build their own models or explore a pre-built model. Analysis of Camtasia videos of student pairs reveals that builders' and explorers' ways of accessing rules, and sense-making of observed trends are of a different character. Builders notice rules through available blocks-based primitives, often bypassing their enactment while explorers attend to rules primarily through the enactment. Moreover, builders' sense-making of observed trends is more rule-driven while explorers' is more enactment-driven. Pre and posttests reveal that builders manifest a greater facility with accessing rules, providing explanations manifesting targeted assembly. Explorers use rules to construct explanations manifesting non-targeted assembly. Interviews reveal varying degrees of shifts away from slippage in both modalities, with students who built models not incorporating slippage explanations in responses. Study 3 compares these modalities with a control using traditional activities. Pre and posttests reveal that the two modalities manifested greater facility with accessing and assembling rules than the control. The dissertation offers implications for the design of learning environments for evolutionary change, design of the two modalities based on their strengths and weaknesses, and teacher training for the same.

  20. Soundscape in the sustainable living environment: A cross-cultural comparison between the UK and Taiwan.

    PubMed

    Yu, Chia-Jen; Kang, Jian

    2014-06-01

    This study examines the effects of cultural factors on the evaluation of acoustic quality of residential areas, within the context of general environmental conditions. A comparative study was carried out between the UK and Taiwan, through questionnaire surveys at three stages, namely in selected residential areas, with respondents in their place of work/study, and using a web-based survey, respectively. This study reveals the importance of considering cultural factors, as well as their living experiences. This is reflected by the significant differences between the two cultures in a number of aspects, including choosing and evaluating living environment, noise noticeability, annoyance and sleep disturbance, activities, and sound preference. It is interesting to note the factor 'quiet' is an important consideration compared to other factors, in both the UK and Taiwan. Crown Copyright © 2013. Published by Elsevier B.V. All rights reserved.

  1. Delamination of Pearlitic Steel Wires: The Defining Role of Prior-Drawing Microstructure

    NASA Astrophysics Data System (ADS)

    Durgaprasad, A.; Giri, S.; Lenka, S.; Sarkar, Sudip Kumar; Biswas, Aniruddha; Kundu, S.; Mishra, S.; Chandra, S.; Doherty, R. D.; Samajdar, I.

    2018-06-01

    This article reports the occasional (< 10 pct of the actual production) delamination of pearlitic wires subjected to a drawing strain of 2.5. The original wire rods which exhibited post-drawing delamination had noticeably lower axial alignment of the pearlite: 22 ± 5 pct vs 34 ± 4 pct in the nondelaminated wires. Although all wires had similar through-thickness texture and stress gradients, delaminated wires had stronger gradients in composition and higher hardness across the ferrite-cementite interface. Carbide dissolution and formation of supersaturated ferrite were clearly correlated with delamination, which could be effectively mitigated by controlled laboratory annealing at 673 K. Direct observations on samples subjected to simple shear revealed significant differences in shear localizations. These were controlled by pearlite morphology and interlamellar spacing. Prior-drawing microstructure of coarse misaligned pearlite thus emerged as a critical factor in the wire drawing-induced delamination of the pearlitic wires.

  2. [Coffee drinking and health - the current state of knowledge. whether the end of the doubts of patients is already coming?

    PubMed

    Wierzejska, Regina

    The impact of drinking coffee on health is still relevant in medicine. Patients, as well as some doctors noticed coffee as the product which can cause or increase a risk a lot of health complaints. However contemporary scientific researches are more optimistic and revealed that coffee doesn't have such negative impact on health, and what's more can has beneficial action. In spite of some differences in findings many of them demonstrated a lack of relationship between coffee and blood pressure, cancers, and in case of type 2 diabetes and neurodegenerative diseases even a protective action is possible. Drinking moderate amount of coffee, brewed using filters (3-4 cups a day) is preferred. Polyphenols are the main of bioactive components of coffee which act as antioxidants and can explain a positive impact of coffee on health.

  3. Does Gender Matter? an Exploratory Study of Perspectives Across Genders, Age and Education

    NASA Astrophysics Data System (ADS)

    Carinci, Sherrie; Wong, Pia Lindquist

    2009-11-01

    Using a convenience sample and survey research methods, the authors seek to better understand how perspectives on gender are shaped by individuals' age, level of education and gender. Study participants responded in writing to scenarios and survey questions, revealing their personal views on gender as an identity category and as a marker in the social hierarchy. Analysis indicated that there were differences between male and female views on these dimensions of gender, and that age and educational levels were also influential. While younger respondents from both genders demonstrated flexibility in their definitions of gender and expressed strong support for gender equality, they were noticeably lacking in their knowledge of the historical context of gender relations and did not show the skills required to realise their ideals of gender equality, especially when compared to older respondents of both genders with higher levels of educational attainment.

  4. Heavy Deformation of Patented Near-Eutectoid Steel

    NASA Astrophysics Data System (ADS)

    Khanchandani, Heena; Banerjee, M. K.

    2018-01-01

    Evolution of microstructure in the patented near-eutectoid steel, forged under varying situations, is critically examined in the present investigation. Steel with 0.74 wt.% carbon is isothermally annealed at 500 °C to obtain fine pearlite microstructure. Steel samples, so patented, are subjected to mechanical deformation by forging at various temperatures with different amount of thickness reduction. Microstructural analyses have revealed that mechanical deformation by forging at lower temperatures brings about partial dissolution of cementite, which is followed by the formation of ɛ-carbide in the microstructures. In contrast, cementite is precipitated within ferrite matrix upon warm or hot forging at higher temperatures. It is further observed that increasing deformation percent during low-temperature forging reduces interlamellar spacing of pearlite, whereas an opposite trend is noticed in case of deformation at higher temperature; moreover, deformation induced the change in interlamellar spacing and formation of fine carbide phases in microstructures has caused appreciable enhancement in hardness of the steel.

  5. Nanoscale phase separation of antiferromagnetic order and superconductivity in K0.75Fe1.75Se2

    PubMed Central

    Yuan, R. H.; Dong, T.; Song, Y. J.; Zheng, P.; Chen, G. F.; Hu, J. P.; Li, J. Q.; Wang, N. L.

    2012-01-01

    We report an in-plane optical spectroscopy study on the iron-selenide superconductor K0.75Fe1.75Se2. The measurement revealed the development of a sharp reflectance edge below Tc at frequency much smaller than the superconducting energy gap on a relatively incoherent electronic background, a phenomenon which was not seen in any other Fe-based superconductors so far investigated. Furthermore, the feature could be noticeably suppressed and shifted to lower frequency by a moderate magnetic field. Our analysis indicates that this edge structure arises from the development of a Josephson-coupling plasmon in the superconducting condensate. Together with the transmission electron microscopy analysis, our study yields compelling evidence for the presence of nanoscale phase separation between superconductivity and magnetism. The results also enable us to understand various seemingly controversial experimental data probed from different techniques. PMID:22355735

  6. Surface and magnetic characteristics of Ni-Mn-Ga/Si (100) thin film

    NASA Astrophysics Data System (ADS)

    Kumar, S. Vinodh; Raja, M. Manivel; Pandi, R. Senthur; Pandyan, R. Kodi; Mahendran, M.

    2016-05-01

    Polycrystalline Ni-Mn-Ga thin films have been deposited on Si (100) substrate with different film thickness. The influence of film thickness on the phase structure and magnetic domain of the films has been examined by scanning electron microscope, atomic force microscopy and magnetic force microscopy. Analysis of structural parameters indicates that the film at lower thickness exhibits the coexistence of both austenite and martensite phase, whereas at higher thickness L12 cubic non magnetic phase is noticed. The grains size and the surface roughness increase along with the film thickness and attain the maximum of 45 nm and 34.96 nm, respectively. At lower film thickness, the magnetic stripe domain is found like maze pattern with dark and bright images, while at higher thickness the absence of stripe domains is observed. The magnetic results reveal that the films strongly depend on their phase structure and microstructure which influence by the film thickness.

  7. The long-term effects of radiation therapy on patients with ovarian dysgerminoma

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mitchell, M.F.; Gershenson, D.M.; Soeters, R.P.

    A retrospective chart review and questionnaire study was undertaken to look at the long-term effects of radiation therapy in ovarian dysgerminoma patients. Forty-three patients and 55 controls responded to a questionnaire that detailed bowel, bladder, thyroid, menstrual, reproductive, sexual, and growth function. Statistically significant differences in the number of bowel movements were noticed when comparing patients with controls. The authors noticed no significant differences between cases and controls in bladder function. No thyroid disorders were attributable to mediastinal radiation therapy. Most patients with intact uteri bleed monthly on hormonal replacement. Three patients with a remaining ovary and uterus resumed menstrualmore » function after substantial doses of abdominopelvic radiation therapy. No patients have conceived. The authors noticed a slight increase in dyspareunia in the treated group, but most patients were satisfied with their sexual function. One premenarchal patient exhibited a growth disorder.« less

  8. A longitudinal study of changes in noticing and treating patients' overweight by Dutch GPs between 1997 and 2007.

    PubMed

    van Dijk, Elske; Kampen, Jarl K; Hiddink, Gerrit J; Renes, Reint Jan; van Binsbergen, Jaap J; van Woerkum, Cees M J

    2012-04-01

    One of the stakeholders in tackling the rise and health consequences of overweight and obesity is the general practice physician (GP). GPs are in a good position to inform and give nutrition guidance to overweight patients. Assessment of working mechanism of determinants of the nutrition guidance practice: noticing patients' overweight and guidance of treatment by GPs [linear analysis of structural relations (LISREL) path model] in a longitudinal study. This longitudinal study measured data in 1992, 1997 and 2007. The 1992 LISREL path model (Hiddink GJ, Hautvast J, van Woerkum CMJ, Fieren CJ, van t'Hof MA. Nutrition guidance by primary-care physicians: LISREL analysis improves understanding. Prev Med 1997; 26: 29-36.) demonstrated that 'noticing patients' overweight and guidance of treatment' was directly and indirectly influenced by predisposing factors, driving forces and perceived barriers. This article defines and discusses the path analysis of the 2007 data (compared with 1997). This analysis shows both similarity and differences in working mechanism of determinants of noticing patients' overweight and guidance of treatment between 1997 and 2007. The backbone of the mechanism with four predisposing factors is the similarity. The number of driving forces and of paths through intermediary factors to the dependent variable constitutes the difference. The backbone of the working mechanism of determinants of the nutrition guidance practice: noticing patients' overweight and guidance of treatment by GPs was similar in 2007 and 1997. The influence of GPs task perception on noticing patients' overweight and guidance of treatment considerably increased in 2007 compared to 1997. The longitudinal character of this article gives a strong practice-based evidence for weight management by GPs.

  9. 32 CFR 644.87 - Preparation and execution of offers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... provisions of §§ 644.81(c), 644.82(a), and 664.86 are not applicable or can be fully complied with without... to Sell. (9) The name and address of the person or persons to whom notice of acceptance is to be sent... property, if different from the address to which the notice is to be sent, should be obtained. (b...

  10. Biofilm-Forming Abilities of Listeria monocytogenes Serotypes Isolated from Different Sources

    PubMed Central

    Doijad, Swapnil P.; Barbuddhe, Sukhadeo B.; Garg, Sandeep; Poharkar, Krupali V.; Kalorey, Dewanand R.; Kurkure, Nitin V.; Rawool, Deepak B.; Chakraborty, Trinad

    2015-01-01

    A total of 98 previously characterized and serotyped L. monocytogenes strains, comprising 32 of 1/2a; 20 of 1/2b and 46 of 4b serotype, from clinical and food sources were studied for their capability to form a biofilm. The microtiter plate assay revealed 62 (63.26%) strains as weak, 27 (27.55%) strains as moderate, and 9 (9.18%) strains as strong biofilm formers. Among the strong biofilm formers, 6 strains were of serotype 1/2a and 3 strains were of serotype 1/2b. None of the strain from 4b serotype exhibited strong biofilm formation. No firm correlation (p = 0.015) was noticed between any serotype and respective biofilm formation ability. Electron microscopic studies showed that strong biofilm forming isolates could synthesize a biofilm within 24 h on surfaces important in food industries such as stainless steel, ceramic tiles, high-density polyethylene plastics, polyvinyl chloride pipes, and glass. Cell enumeration of strong, moderate, and weak biofilm was performed to determine if the number of cells correlated with the biofilm-forming capabilities of the isolates. Strong, moderate, and weak biofilm showed 570±127× 103 cells/cm2, 33±26× 103 cells/cm2, 5±3× 103 cells/cm2, respectively, indicating that the number of cells was directly proportional to the strength of the biofilm. The hydrophobicity index (HI) analysis revealed higher hydrophobicity with an increased biofilm formation. Fatty acid methyl esterase analysis revealed the amount of certain fatty acids such as iso-C15:0, anteiso-C15:0, and anteiso-C17:0 fatty acids correlated with the biofilm-forming capability of L. monocytogenes. This study showed that different strains of L. monocytogenes form biofilm of different intensities which did not completely correlate with their serotype; however, it correlated with the number of cells, hydrophobicity, and amount of certain fatty acids. PMID:26360831

  11. Temporal patterns of rat behaviour in the central platform of the elevated plus maze. Comparative analysis between male subjects of strains with different basal levels of emotionality.

    PubMed

    Casarrubea, M; Faulisi, F; Caternicchia, F; Santangelo, A; Di Giovanni, G; Benigno, A; Magnusson, M S; Crescimanno, G

    2016-08-01

    We have analyzed the temporal patterns of behaviour of male rats of the Wistar and DA/Han strains on the central platform of the elevated plus maze. The ethogram encompassed 10 behavioural elements. Durations, frequencies and latencies showed quantitative differences as to walking and sniffing activities. Wistar rats displayed significantly lower latency and significantly higher durations and frequencies of walking activities. DA/Han rats showed a significant increase of sniffing duration. In addition, DA/Han rats showed a significantly higher amount of time spent in the central platform. Multivariate T-pattern analysis revealed differences in the temporal organization of behaviour of the two rat strains. DA/Han rats showed (a) higher behavioural complexity and variability and (b) a significantly higher mean number of T-patterns than Wistar rats. Taken together, T-pattern analysis of behaviour in the centre of the elevated plus maze can noticeably improve the detection of subtle features of anxiety related behaviour. We suggest that T-pattern analysis could be used as sensitive tool to test the action of anxiolytic and anxiogenic manipulations. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. A No-Notice Drill of Hospital Preparedness in Responding to Ebola Virus Disease in Taiwan.

    PubMed

    Hsu, Shih-Min; Chien, Li-Jung; Tseng, Shu-Hui; Kuo, Steve H S

    2015-01-01

    The Ebola virus was first discovered in 1976, but the outbreak of Ebola virus disease that began in Guinea, West Africa, in December 2013 shocked the world. It is the largest and most severe epidemic of Ebola virus disease to date. The US Centers for Disease Control and Prevention confirmed that inadequate implementation of the policy of acquiring travel history led to a delay in identifying the first imported Ebola virus disease case. The Taiwan Centers for Disease Control developed a no-notice drill that used a simulated patient to assess hospitals' emergency preparedness capacity in responding to Ebola virus disease. Despite the fact that regular inspection shows that more than 90% of regional hospitals and medical centers inquired about patients' travel history, occupation, contact history, and cluster information, the no-notice drill revealed that more than 40% of regional hospitals and medical centers failed to ask emergency room patients about these factors. Therefore, to assist in inquiries about travel history, occupation, contact history, and cluster information in emergency triage and outpatient settings, the Taiwan CDC revised the criteria for hospital infection control inspection. It requested that hospitals issue appropriate reminders and implement process control mechanisms to block diagnostic processes in instances in which healthcare workers do not inquire about travel history, occupation, contact history, and cluster information. Furthermore, the Taiwan CDC will continue no-notice inspections in order to strengthen hospitals' infection control measures and reduce the risk of infectious disease transmission in the healthcare system.

  13. Gravity waves, Tides and Planetary wave characteristics revealed by network of MLT radars over Indian region

    NASA Astrophysics Data System (ADS)

    Venkat Ratnam, Madineni; Karanam, Kishore Kumar; Sunkara, Eswaraiah; Vijaya Bhaskara Rao, S.; Subrahmanyam, K. V.; Ramanjaneyulu, L.

    2016-07-01

    Mesosphere and Lower Thermosphere (MLT) mean winds, gravity waves, tidal and planetary wave characteristics are investigated using two years (2013-2015) of advanced meteor radar installed at Tirupathi (13.63oN, 79.4oE), India. The observations reveal the presence of high frequency gravity waves (30-120 minutes), atmospheric tides (diurnal, semi-diurnal and terr-diurnal) along with long period oscillations in both zonal and meridional winds. Background mean zonal winds show clear semi-annual oscillation in the mesosphere, whereas meridional winds are characterized by annual oscillation as expected. Diurnal tide amplitudes are significantly larger (60-80 m/s) than semi-diurnal (10-20 m/s) and terr-diurnal (5-8 m/s) tides and larger in meridional than zonal winds. The measured meridional components are in good agreement with Global Scale Wave Model (GSWM-09) predictions than zonal up to ~90 km in all the seasons, except fall equinox. Diurnal tidal phase matches well than the amplitudes between observations and model predictions. However, no similarity is being found in the semi-diurnal tides between observations and model. The measurements are further compared with nearby Thumba meteor radar (8.5oN, 77oE) observations. Some differences do exist between the measurements from Tirupati and Thumba meteor radar and model outputs at greater heights and the possible reasons are discussed. SVU meteor radar observations clearly showed the dominance of well-known ultra-fast kelvin waves (3.5 days), 5-8 day, 16 day, 27 day, and 30-40 day oscillations. Due to higher meteor count extending up to 110 km, we could investigate the variability of these PWs and oscillations covering wider range (70-110 km) for the first time. Significant change above 100 km is noticed in all the above mentioned PW activity and oscillations. We also used ERA-Interim reanalysis data sets available at 0.125x0.125 degree grids for investigating the characteristics of these PW right from surface to 1 hPa. The presence of these waves and oscillations right from upper troposphere to lower thermosphere simultaneously is noticed. Though these waves are expected to have higher wave number (higher horizontal wave lengths) few important differences are noticed between Tirupati and Thumba, that are separated by only 500 km. The implication of these waves and oscillations on the background atmosphere and vice versa are discussed. Thus, installation of SVU meteor radar made good complementary observations that can be effectively used to investigate vertical and lateral coupling. Role of these tides in modulating the mesopause altitude is further investigated using the Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) on-board Thermosphere Ionosphere Mesosphere Energetics Dynamics (TIMED) satellite. It is found that mesopause altitude is always close to 100 km and is strongly affected by gravity waves, tides and planetary waves.

  14. Development of criteria for the use of asphalt-rubber as a Stress-Absorbing Membrane Interlayer (SAMI)

    NASA Astrophysics Data System (ADS)

    Newcomb, D. E.; McKeen, R. G.

    1983-12-01

    This report documents over 2 years of research efforts to characterize asphalt-rubber mixtures to be used in Stress-Absorbing Membrane Interlayers (SAMI). The purpose of these SAMIs is to retard or prevent reflection cracking in asphalt-concrete overlays. Several laboratory experiments and one field trial were conducted to define significant test methods and parameters for incorporation into construction design and specification documents. Test methods used in this study included a modified softening point test, force-ductility, and Schweyer viscosity. Variables investigated included (1) Laboratory-mixing temperature; (2) Rubber type; (3) Laboratory storage time; (4) Laboratory storage condition; (5) Laboratory batch replication; (6) Laboratory mixing time; (7) Field mixing time; (8) Laboratory test temperature; (9) Force-Ductility elongation rates; and (10) Asphalt grade. It was found that mixing temperature, mixing time, rubber type, and asphalt grade all have significant effects upon the behavior of asphalt-rubber mixtures. Significant variability was also noticed in different laboratory batch replications. Varying laboratory test temperature and force-ductility elongation rate revealed further differences in asphalt-rubber mixtures.

  15. Sauter mean diameter statistics of the starch dispersion atomized with hydraulic nozzle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Naz, Muhammad Yasin, E-mail: yasin603@yahoo.com; Ariwahjoedi, Bambang, E-mail: bambang-ariwahjoedi@petronas.com.my; Sulaiman, Shaharin Anwar, E-mail: shaharin@petronas.com.my

    In the reported research work, the microscopic droplet velocity at different axial and radial locations downstream to the nozzle exit was studied by using a non-intrusive Laser Doppler Anemometry (LDA) techniques. These velocity measurements made in the viscous fluid spray sterams were used to predict the different breakup regimes in the flow. It was noticed that the droplet velocity decreased sharply downstream to the nozzle exit, whereas steady decrease in velocity was seen along the radial directions. For shorter injection time periods, the velocity downstream to the nozzle was not following the general breakup model. However, along the radial directionmore » it exactly followed the discussed model. Along the spray centerline, the velocity was decreasing sharply even at far points from the nozzle exit. It was difficult to identify the core region, transition region and fully developed spray region in the flow. It revealed that the jet breakup was not completed yet and further disintegration was taking place along the spray centerline for shorter injection periods below 250 ms.« less

  16. Patterns and sources of adult personality development: growth curve analyses of the NEO PI-R scales in a longitudinal twin study.

    PubMed

    Bleidorn, Wiebke; Kandler, Christian; Riemann, Rainer; Spinath, Frank M; Angleitner, Alois

    2009-07-01

    The present study examined the patterns and sources of 10-year stability and change of adult personality assessed by the 5 domains and 30 facets of the Revised NEO Personality Inventory. Phenotypic and biometric analyses were performed on data from 126 identical and 61 fraternal twins from the Bielefeld Longitudinal Study of Adult Twins (BiLSAT). Consistent with previous research, LGM analyses revealed significant mean-level changes in domains and facets suggesting maturation of personality. There were also substantial individual differences in the change trajectories of both domain and facet scales. Correlations between age and trait changes were modest and there were no significant associations between change and gender. Biometric extensions of growth curve models showed that 10-year stability and change of personality were influenced by both genetic as well as environmental factors. Regarding the etiology of change, the analyses uncovered a more complex picture than originally stated, as findings suggest noticeable differences between traits with respect to the magnitude of genetic and environmental effects. (PsycINFO Database Record (c) 2009 APA, all rights reserved).

  17. Mg2+ -Dependent High Mechanical Anisotropy of Three-Way-Junction pRNA as Revealed by Single-Molecule Force Spectroscopy.

    PubMed

    Sun, Yang; Di, Weishuai; Li, Yiran; Huang, Wenmao; Wang, Xin; Qin, Meng; Wang, Wei; Cao, Yi

    2017-08-01

    Mechanical anisotropy is ubiquitous in biological tissues but is hard to reproduce in synthetic biomaterials. Developing molecular building blocks with anisotropic mechanical response is the key towards engineering anisotropic biomaterials. The three-way-junction (3WJ) pRNA, derived from ϕ29 DNA packaging motor, shows strong mechanical anisotropy upon Mg 2+ binding. In the absence of Mg 2+ , 3WJ-pRNA is mechanically weak without noticeable mechanical anisotropy. In the presence of Mg 2+ , the unfolding forces can differ by more than 4-fold along different pulling directions, ranging from about 47 pN to about 219 pN. Mechanical anisotropy of 3WJ-pRNA stems from pulling direction dependent cooperativity for the rupture of two Mg 2+ binding sites, which is a novel mechanism for the mechanical anisotropy of biomacromolecules. It is anticipated that 3WJ-pRNA can be used as a key element for the construction of biomaterials with controllable mechanical anisotropy. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Hydroxypropyl-β-cyclodextrin-containing hydrogel enhances skin formononetin permeation/retention.

    PubMed

    Dias, Paula Hollweg; Scopel, Marina; Martiny, Simony; Bianchi, Sara Elis; Bassani, Valquiria Linck; Zuanazzi, José Angelo Silveira

    2018-04-10

    This study was aimed to investigate the in vitro permeation potential of hydrogel formulations containing the isoflavones formononetin and biochanin A and cyclodextrins in different combinations. The permeation assay was performed using porcine skin discs on Franz diffusion cells model. The isoflavone contents of the formulations were quantified in the different layers of the skin using a validated HPLC-PDA method. The isoflavones individually incorporated into the formulations showed high permeation potential, especially formononetin, after the incorporation of hydroxypropyl-β-cyclodextrin that enhanced its permeation in the epidermis and dermis. Biochanin A showed 2.7 times of permeation capacity in the epidermis and dermis mainly after incorporation of cyclodextrins in the formulations. Formononetin showed reduction in its permeation when incorporated in the formulations together to biochanin A, showing the absence of synergism. Our results indicated a noticeable skin permeation promoting effect of HPβCD in formononetin formulation. Furthermore, formononetin and biochanin A can permeate the skin being mostly retained in the epidermis and dermis, revealing its potential use in cosmetic preparations intended to prevent skin aging. © 2018 Royal Pharmaceutical Society.

  19. Influence of technical processing units on chemical composition and antimicrobial activity of carrot (Daucus carrot L.) juice essential oil.

    PubMed

    Ma, Tingting; Luo, Jiyang; Tian, Chengrui; Sun, Xiangyu; Quan, Meiping; Zheng, Cuiping; Kang, Lina; Zhan, Jicheng

    2015-03-01

    The effect of three processing units (blanching, enzyme liquefaction, pasteurisation) on chemical composition and antimicrobial activity of carrot juice essential oil was investigated in this paper. A total of 36 compounds were identified by GC-MS from fresh carrot juice essential oil. The main constituents were carotol (20.20%), sabinene (12.80%), β-caryophyllene (8.04%) and α-pinene (6.05%). Compared with the oil of fresh juice, blanching and pasteurisation could significantly decrease the components of the juice essential oil, whereas enzyme liquefaction had no considerable effect on the composition of juice essential oil. With regard to the antimicrobial activity, carrot juice essential oil could cause physical damage and morphological alteration on microorganisms, while the three different processing units showed noticeable differences on the species of microorganisms, the minimum inhibitory concentration and minimum bactericidal concentration. Results revealed that the carrot juice essential oil has great potential for application as a natural antimicrobial applied in pharmaceutical and food industries. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Space Weather: Measurements, Models and Predictions

    DTIC Science & Technology

    2014-03-21

    divided by 16. A review of the data processing revealed some small changes between 1994 and the current software. These changes explain slight...are working with Dr. Chad Lindstrom at AFRL in performing spectral inversion on the CEASE data . One issue is that in order to extend the inversions...FORCE BASE, NM 87117-5776 DTIC COPY NOTICE AND SIGNATURE PAGE Using Government drawings, specifications, or other data included in this document

  1. Bcl-2 expression in Hodgkin's lymphoma progression.

    PubMed

    Flangea, Corina; Potencz, Elena; Mihăescu, Rodica; Gîju, S; Anghel, A

    2008-01-01

    Hodgkin's lymphoma study by immunohistochemical expression of Bcl-2 in Hodgkin and Reed-Sternberg cells can precise these cases evolutive way. Sixty-three cases of classical Hodgkin's disease, hospitalized into the Hematology Department of the County Hospital No. 1 Timisoara, were studied. Histopathological diagnostic was performed using common staining methods, and for revealing the tumoral developments immunohistochemical staining was performed Bcl-2. In our study, the results were noticed a direct relation between the rise of tumoral proliferation index expressions of Bcl-2 and progression of the disease (p < or = 0.001). For I and II stages Bcl-2 expression does not overcome (-/+) category while the III and IV stages, all the cases are situated in (+/-) and (+) categories. No connection we can be noticed between the histological type and Bcl-2 expression although the classic Hodgkin's lymphoma with lymphocyte depletion is considered the most aggressive histological type (p < or = 1). In our study, we found this correlation very important because the main cause of relapses is inadequate staging. In some cases, this staging is difficult; some little lymph nodes could be overlooked because they can be placed in less accessible areas and cannot be evidenced by the most imagistic methods. All the cases were Bcl-2 expression higher than (+/-) and are staged as I and II stages should be reinvestigated and restaged. This immunohistochemical reaction, although less used in Romania, is very accurate. That is very important because the therapeutically attitude is different in advances stages compared to earlier stages.

  2. Characterizing the Nature of Students' Feature Noticing-and-Using with Respect to Mathematical Symbols across Different Levels of Algebra Exposure

    ERIC Educational Resources Information Center

    Sullivan, Patrick

    2013-01-01

    The purpose of this study is to examine the nature of what students notice about symbols and use as they solve unfamiliar algebra problems based on familiar algebra concepts and involving symbolic inscriptions. The researcher conducted a study of students at three levels of algebra exposure: (a) students enrolled in a high school pre-calculus…

  3. A mechanism for value-sensitive decision-making.

    PubMed

    Pais, Darren; Hogan, Patrick M; Schlegel, Thomas; Franks, Nigel R; Leonard, Naomi E; Marshall, James A R

    2013-01-01

    We present a dynamical systems analysis of a decision-making mechanism inspired by collective choice in house-hunting honeybee swarms, revealing the crucial role of cross-inhibitory 'stop-signalling' in improving the decision-making capabilities. We show that strength of cross-inhibition is a decision-parameter influencing how decisions depend both on the difference in value and on the mean value of the alternatives; this is in contrast to many previous mechanistic models of decision-making, which are typically sensitive to decision accuracy rather than the value of the option chosen. The strength of cross-inhibition determines when deadlock over similarly valued alternatives is maintained or broken, as a function of the mean value; thus, changes in cross-inhibition strength allow adaptive time-dependent decision-making strategies. Cross-inhibition also tunes the minimum difference between alternatives required for reliable discrimination, in a manner similar to Weber's law of just-noticeable difference. Finally, cross-inhibition tunes the speed-accuracy trade-off realised when differences in the values of the alternatives are sufficiently large to matter. We propose that the model, and the significant role of the values of the alternatives, may describe other decision-making systems, including intracellular regulatory circuits, and simple neural circuits, and may provide guidance in the design of decision-making algorithms for artificial systems, particularly those functioning without centralised control.

  4. Deformation behavior of open-cell dry natural rubber foam: Effect of different concentration of blowing agent and compression strain rate

    NASA Astrophysics Data System (ADS)

    Samsudin, M. S. F.; Ariff, Z. M.; Ariffin, A.

    2017-04-01

    Compression and deformation behavior of partially open cell natural rubber (NR) foam produced from dry natural rubber (DNR), were investigated by performing compressive deformation at different strains and strain rates. Different concentrations of sodium bicarbonate as a blowing agent (BA) were utilized, from 4 to 16 phr in order to produce foams with range of cell size and morphology. Overall, increasing of blowing agent concentration had significantly changed relative foam density. Compression stress-strain curves of the foams exhibited that the compression behavior was directly correlated to the foam cells morphology and physical density. Pronounced changes were noticed for foams with bigger cells particularly at 4 phr concentration of BA where the compression stress at plateau region was greater compared to those with higher concentration of BA. Cell deformation progressive images confirmed that the foams demonstrated small degree of struts bending at 15% of strain and followed by continuous severe struts bending and elastic buckling up to 50% of strain. Compression test at different strain rates revealed that the strain rate factor only affected the foams with 4 phr of BA by causing immediate increment in the compression stress value when higher strain rate was applied.

  5. Tinea nigra showing a parallel ridge pattern on dermoscopy.

    PubMed

    Noguchi, Hiromitsu; Hiruma, Masataro; Inoue, Yuji; Miyata, Keishi; Tanaka, Masaru; Ihn, Hironobu

    2015-05-01

    An 18-year-old healthy female student noticed a brown macule measuring 21 mm in diameter on the left palm and visited our clinic concerned about a cancerous mole. Dermoscopic examination revealed a brown, fine-dotted and granule-like structure overlapping an amorphous light brown macule. However, unlike previous cases, analysis of the high dynamic range-converted image revealed the parallel ridge pattern frequently observed in malignant melanomas. Brown mycelia were detected on direct microscopic examination; black colonies were isolated on fungal culture and the fungus was identified as Hortaea werneckii. The lesion was treated with topical ketoconazole cream, and it diminished 1 month later. © 2015 Japanese Dermatological Association.

  6. Investigating Elementary Teachers' Thinking About and Learning to Notice Students' Science Ideas

    NASA Astrophysics Data System (ADS)

    Luna, Melissa Jo

    Children naturally use observations and everyday thinking to construct explanations as to why phenomena happen in the world. Science instruction can benefit by starting with these ideas to help children build coherent scientific understandings of how the physical world works. To do so, science teaching must involve attending to students' ideas so that those ideas become the basis for learning. Yet while science education reform requires teachers to pay close attention to their students' ideas, we know little about what teachers think this means in practice. To examine this issue, my dissertation research is two-fold. First, I examine teacher thinking by investigating how teachers understand what it means to pay attention to students' science ideas. Specifically, using new digital technology, three participating teachers captured moments of student thinking in the midst of instruction. Analysis of these moments reveals that teachers capture many different kinds of moments containing students' ideas and think about students' science ideas in different ways at different times. In particular, these three teachers most often think about students' ideas as being (a) from authority, (b) from experience, and (c) under construction. Second, I examine teacher learning through the development of an innovative science teaching video club model. The model differs from previous research on video clubs in several key ways in an attempt to focus teachers on student thinking in a sustained way. I investigate the ways in which this model was effective for engaging teachers in noticing and making sense of their students' science ideas during one implementation. Results indicate that teachers talked about student thinking early, often, and in meaningful ways. Science education leaders have recognized the potential of science teaching video clubs as a form of professional development, and the model presented in this work promotes the conditions for successful teacher learning. This work contributes to research on teacher cognition by advancing what we know about teachers' understanding of attending to students' science ideas. In addition, it provides practical information concerning the design of teacher professional development supporting their learning to attend closely to the ideas students raise about scientific phenomena.

  7. A model for the perception of environmental sound based on notice-events.

    PubMed

    De Coensel, Bert; Botteldooren, Dick; De Muer, Tom; Berglund, Birgitta; Nilsson, Mats E; Lercher, Peter

    2009-08-01

    An approach is proposed to shed light on the mechanisms underlying human perception of environmental sound that intrudes in everyday living. Most research on exposure-effect relationships aims at relating overall effects to overall exposure indicators in an epidemiological fashion, without including available knowledge on the possible underlying mechanisms. Here, it is proposed to start from available knowledge on audition and perception to construct a computational framework for the effect of environmental sound on individuals. Obviously, at the individual level additional mechanisms (inter-sensory, attentional, cognitive, emotional) play a role in the perception of environmental sound. As a first step, current knowledge is made explicit by building a model mimicking some aspects of human auditory perception. This model is grounded in the hypothesis that long-term perception of environmental sound is determined primarily by short notice-events. The applicability of the notice-event model is illustrated by simulating a synthetic population exposed to typical Flemish environmental noise. From these simulation results, it is demonstrated that the notice-event model is able to mimic the differences between the annoyance caused by road traffic noise exposure and railway traffic noise exposure that are also observed empirically in other studies and thus could provide an explanation for these differences.

  8. Studying dielectric mechanism and magnetization of double perovskite Gd{sub 2}NiMnO{sub 6} ceramic

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mohapatra, S. R.; Sahu, B., E-mail: 512PH3009@nitrkl.ac.in; Singh, A. K.

    2016-05-23

    In the present work, the structure, dielectric and magnetic properties of Gd{sub 2}NiMnO{sub 6} double perovskite have been studied. X-Ray diffraction study reveals the phase pure formation of the material that crystallizes into monoclinic phase (space group ’P2{sub 1}/n’). Surface morphology depicts heterogeneous grain distribution with average grain size of ~1 µm. Temperature dependent (50 – 330 K) dielectric measurements at different frequencies (0.5 - 50 kHz) relate to Maxwell-Wagner interfacial polarization model. Giant dielectric constant at 1 kHz for 300 K (ε’ ~1900) is noticed as compared to that of 50 K (ε’ ~10) coupled with a peak shiftmore » in tan loss towards higher temperature with frequency. The activation energy (0.24 eV) obtained using Arrhenius relation for thermally activated relaxor behavior of the material signifies an electron hopping mechanism between Ni{sup 2+} and Mn{sup 4+} cations. Lastly, M-H study shows ‘S’ shape hysteresis loop at 50 K with remnant magnetization (M{sub r}) of 0.72 µ{sub B}/f.u. along with a linear plot for 300 K which reveals paramagnetic nature of the material.« less

  9. Structural properties of Sb 2S 3 under pressure: Evidence of an electronic topological transition

    DOE PAGES

    Efthimiopoulos, Ilias; Buchan, Cienna; Wang, Yuejian

    2016-04-06

    High-pressure Raman spectroscopy and x-ray diffraction of Sb 2S 3 up to 53 GPa reveals two phase transitions at 5 GPa and 15 GPa. The first transition is evidenced by noticeable compressibility changes in distinct Raman-active modes, in the lattice parameter axial ratios, the unit cell volume, as well as in specific interatomic bond lengths and bond angles. By taking into account relevant results from the literature, we assign these effects to a second-order isostructural transition arising from an electronic topological transition in Sb 2S 3 near 5 GPa. Close comparison between Sb 2S 3 and Sb 2S 3 upmore » to 10 GPa reveals a slightly diverse structural behavior for these two compounds after the isostructural transition pressure. This structural diversity appears to account for the different pressure-induced electronic behavior of Sb 2S 3 and Sb 2S 3 up to 10 GPa, i.e. the absence of an insulator-metal transition in Sb 2S 3 up to that pressure. Lastly, the second high-pressure modification appearing above 15 GPa appears to trigger a structural disorder at ~20 GPa; full decompression from 53 GPa leads to the recovery of an amorphous state.« less

  10. Disparities of Selected Metal Levels in the Blood and Scalp Hair of Ischemia Heart Disease Patients and Healthy Subjects.

    PubMed

    Ilyas, Asim; Shah, Munir H

    2017-12-01

    Imbalances in the concentrations of trace metals have become an increasingly recognized source of infirmity worldwide particularly in the development of ischemia heart disease (IHD). Present study is intended to analyze the concentrations of Ca, Cd, Co, Cr, Cu, Fe, K, Li, Mg, Mn, Na, Pb, Sr, and Zn in the blood and scalp hair of the patients and counterpart controls by flame atomic absorption spectrometry after wet-acid digestion. On the average, Cd, Co, Cr, Fe, K, Li, Mn, Na, and Pb revealed significantly elevated concentrations in the blood of the patients compared with the controls (p < 0.05), whereas mean levels of Ca, Cd, Fe, K, Li, Pb, and Sr in the scalp hair were significantly higher in the patients than the controls (p < 0.05). Most of the metals exhibited noticeable disparities in their concentrations based on gender, abode, dietary/smoking habits, and occupations of both donor groups. The correlation study and multivariate statistical analyses revealed some significantly divergent associations and apportionment of the metals in both donor groups. Overall, comparative variations of the metal contents in blood/scalp hair of the patients were significantly different than the controls; thus, evaluation of trace metals status may be indicative of pathological disorders, such as IHD.

  11. Full-length VP2 gene analysis of canine parvovirus reveals emergence of newer variants in India.

    PubMed

    Nookala, Mangadevi; Mukhopadhyay, Hirak Kumar; Sivaprakasam, Amsaveni; Balasubramanian, Brindhalakshmi; Antony, Prabhakar Xavier; Thanislass, Jacob; Srinivas, Mouttou Vivek; Pillai, Raghavan Madhusoodanan

    2016-12-01

    The canine parvovirus (CPV) infection is a highly contagious and serious enteric disease of dogs with high fatality rate. The present study was taken up to characterize the full-length viral polypeptide 2 (VP2) gene of CPV of Indian origin along with the commercially available vaccines. The faecal samples from parvovirus suspected dogs were collected from various states of India for screening by PCR assay and 66.29% of samples were found positive. Six CPV-2a, three CPV-2b, and one CPV-2c types were identified by sequence analysis. Several unique and existing mutations have been noticed in CPV types analyzed indicating emergence of newer variants of CPV in India. The phylogenetic analysis revealed that all the field CPV types were grouped in different subclades within two main clades, but away from the commercial vaccine strains. CPV-2b and CPV-2c types with unique mutations were found to be establishing in India apart from the prevailing CPV-2a type. Mutations and the positive selection of the mutants were found to be the major mechanism of emergence and evolution of parvovirus. Therefore, the incorporation of local strain in the vaccine formulation may be considered for effective control of CPV infections in India.

  12. Screening of analgesic activity of Tunisian Urtica dioica and analysis of its major bioactive compounds by GCMS.

    PubMed

    Dhouibi, Raouia; Moalla, Dorsaf; Ksouda, Kamilia; Ben Salem, Maryem; Hammami, Serria; Sahnoun, Zouheir; Zeghal, Khaled Mounir; Affes, Hanen

    2017-11-20

    The present study was aimed to evaluate the analgesic properties of Urtica dioica (UD) and to profile phytochemicals by gas chromatography-mass spectrometry (GC-MS). The ethanolic extracts were prepared by maceration method and extraction using rotary evaporator. The analgesic activity was analysed by hot plate method, formalin test, acetic acid-induced writhing test and the tail-flick test with different doses of the ethanolic extract. In all tests, the leaf's ethanolic extract exhibited significant analgesic activity (p < .001) at a dose of 400 mg/kg. Even with a low dose, we noticed an analgesic activity with many tests. The GC-MS analysis of the ethanol extract of leaf revealed many compounds; 2-methyltetradecane dodecane, 2,6,11-trimethyl-; 2,6,11-trimethyldodecane, and trimethylhexane which are pharmaceutically the most important. These findings justify that UD can be a valuable natural analgesic source which seemed to provide potential phototherapeutics against various ailments. The analysis of ethanolic extract of UD by GCMS revealed the presence of several compounds including polyphenols, flavonoids, triterpenes which can explain the analgesic effect of UD and its mechanism of action. Hence, UD could be another therapeutic alternative for relieving pain and for minimising the use of drugs that have long-term secondary effects.

  13. Speech perception in individuals with auditory dys-synchrony.

    PubMed

    Kumar, U A; Jayaram, M

    2011-03-01

    This study aimed to evaluate the effect of lengthening the transition duration of selected speech segments upon the perception of those segments in individuals with auditory dys-synchrony. Thirty individuals with auditory dys-synchrony participated in the study, along with 30 age-matched normal hearing listeners. Eight consonant-vowel syllables were used as auditory stimuli. Two experiments were conducted. Experiment one measured the 'just noticeable difference' time: the smallest prolongation of the speech sound transition duration which was noticeable by the subject. In experiment two, speech sounds were modified by lengthening the transition duration by multiples of the just noticeable difference time, and subjects' speech identification scores for the modified speech sounds were assessed. Subjects with auditory dys-synchrony demonstrated poor processing of temporal auditory information. Lengthening of speech sound transition duration improved these subjects' perception of both the placement and voicing features of the speech syllables used. These results suggest that innovative speech processing strategies which enhance temporal cues may benefit individuals with auditory dys-synchrony.

  14. Notice, Explore, and Talk About Mathematics: Making a Positive Difference for Preschool Children, Families, and Educators in Australian Communities That Experience Multiple Disadvantages.

    PubMed

    Gervasoni, Ann; Perry, Bob

    2017-01-01

    Let's Count is a preschool mathematics intervention implemented by The Smith Family from 2012 to the present in "disadvantaged" communities across Australia. It is based on current mathematics and early childhood education research and aligns with the Australian Early Years Learning Framework. Let's Count has been shown to be effective in enhancing mathematics learning and dispositions of young children, early childhood educators, and families through a longitudinal evaluation undertaken from 2012 to 2015. In this chapter, the authors explore the development, implementation, and evaluation of Let's Count and highlight the importance of adults noticing, exploring, and talking about children's mathematics. The findings from the longitudinal evaluation of Let's Count suggest that when adults notice children's mathematics, then children's learning thrives, and the positive dispositions and confidence of parents and educators increase. Let's Count has made a positive difference for many children and adults across Australia. © 2017 Elsevier Inc. All rights reserved.

  15. Bacterial density and community structure associated with aggregate size fractions of soil-feeding termite mounds.

    PubMed

    Fall, S; Nazaret, S; Chotte, J L; Brauman, A

    2004-08-01

    The building and foraging activities of termites are known to modify soil characteristics such as the heterogeneity. In tropical savannas the impact of the activity of soil-feeding termites ( Cubitermes niokoloensis) has been shown to affect the properties of the soil at the aggregate level by creating new soil microenvironments (aggregate size fractions) [13]. These changes were investigated in greater depth by looking at the microbial density (AODC) and the genetic structure (automated rRNA intergenic spacer analysis: ARISA) of the communities in the different aggregate size fractions (i.e., coarse sand, fine sand, coarse silt, fine silt, and dispersible clays) separated from compartments (internal and external wall) of three Cubitermes niokoloensis mounds. The bacterial density of the mounds was significantly higher (1.5 to 3 times) than that of the surrounding soil. Within the aggregate size fractions, the termite building activity resulted in a significant increase in bacterial density within the coarser fractions (>20 mum). Multivariate analysis of the ARISA profiles revealed that the bacterial genetic structures of unfractionated soil and soil aggregate size fractions of the three mounds was noticeably different from the savanna soil used as a reference. Moreover, the microbial community associated with the different microenvironments in the three termite mounds revealed three distinct clusters formed by the aggregate size fractions of each mound. Except for the 2-20 mum fraction, these results suggest that the mound microbial genetic structure is more dependent upon microbial pool affiliation (the termite mound) than on the soil location (aggregate size fraction). The causes of the specificity of the microbial community structure of termite mound aggregate size fractions are discussed.

  16. Fast Photochemistry of Prototypical Phytochromes—A Species vs. Subunit Specific Comparison

    PubMed Central

    Ihalainen, Janne A.; Takala, Heikki; Lehtivuori, Heli

    2015-01-01

    Phytochromes are multi-domain red light photosensor proteins, which convert red light photons to biological activity utilizing the multitude of structural and chemical reactions. The steady increase in structural information obtained from various bacteriophytochromes has increased understanding about the functional mechanism of the photochemical processes of the phytochromes. Furthermore, a number of spectroscopic studies have revealed kinetic information about the light-induced reactions. The spectroscopic changes are, however, challenging to connect with the structural changes of the chromophore and the protein environment, as the excited state properties of the chromophores are very sensitive to the small structural and chemical changes of their environment. In this article, we concentrate on the results of ultra-fast spectroscopic experiments which reveal information about the important initial steps of the photoreactions of the phytochromes. We survey the excited state properties obtained during the last few decades. The differences in kinetics between different research laboratories are traditionally related to the differences of the studied species. However, we notice that the variation in the excited state properties depends on the subunit composition of the protein as well. This observation illustrates a feedback mechanism from the other domains to the chromophore. We propose that two feedback routes exist in phytochromes between the chromophore and the remotely located effector domain. The well-known connection between the subunits is the so-called tongue region, which changes its secondary structure while changing the light-activated state of the system. The other feedback route which we suggest is less obvious, it is made up of several water molecules ranging from the dimer interface to the vicinity of the chromophore, allowing even proton transfer reactions nearby the chromophore. PMID:26779488

  17. Dispositional optimism and physical wellbeing: the relevance of culture, gender, and socioeconomic status.

    PubMed

    Khallad, Yacoub

    2013-01-01

    The present study examined the relationship between dispositional optimism and physical wellbeing (as reflected in physical symptom reporting) in two groups of American and Jordanian college students. It also assessed moderation effects of culture, gender, and socioeconomic status (SES). Participants were administered a questionnaire consisting of items pertaining to dispositional optimism (as measured by the Revised Life Orientation Test, LOT-R) along with items assessing physical symptom reporting and sociodemographic factors (e.g., gender, socioeconomic status). The results revealed significant negative correlations between dispositional optimism and physical symptom reporting for both American and Jordanian participants, although the magnitude of the correlation for the American group was noticeably larger than that for the Jordanian group. The results also showed that women, especially Jordanians, were more likely than men to report physical symptoms. Among Jordanians, physical symptom reporting was more common among those of lower SES. No statistically significant differences in physical symptom reporting were found between American men and women or between the two cultural groups. Multiple regression analyses revealed no statistically significant interactions between optimism and cultural background, optimism and gender, or optimism and SES. Overall, the results suggest that optimism is the factor most predictive of physical symptom reporting, followed by SES and gender. These results corroborate previous findings on the relationship between dispositional optimism and physical wellbeing, and point to crosscultural differences in relationship patterns. These differences suggest that although personality characteristics such as optimism may play an important role in the physical wellbeing of both Western and non-Western groups, the influence of sociodemographic factors such as gender and SES and their interaction with cultural variables must not be overlooked.

  18. Clinical study of Mineral Trioxide Aggregate in primary molars. Comparison between Grey and White MTA--a long term follow-up (84 months).

    PubMed

    Cardoso-Silva, Cristina; Barbería, Elena; Maroto, Myriam; García-Godoy, Franklin

    2011-02-01

    The aim of the present study was to conduct a clinical and radiographic long-term evaluation of pulpotomy in temporary molars performed with Grey and White Mineral Trioxide Aggregate (MTA) and compare the results of Grey and White MTA pulpotomies in a sample of 233 primary molars with a maximum follow-up period of 84 months. The sample was selected from patients treated at the Department of Pediatric Dentistry, Faculty of Dentistry, Complutense University of Madrid, Spain. This prospective study included first and second primary molars treated with pulpotomy with Grey or White MTA, controlled for a maximum follow-up period of 84 months. Statistical analysis of clinical and radiographic findings was completed using ANOVA (P<0.05). Follow-up evaluations, performed every 6 months, revealed that only 2 molars treated with White MTA presented abscess and pathological mobility. Radiographic examination of the 210 molars revealed unfavourable pulp response in only 6 molars (internal or furcation root resorption), without statistically significant differences between Grey and White MTA. Two radiological findings were noticed: dentine bridge formation and partial or total root canal stenosis. Grey MTA induced a higher percentage of dentine bridges with statistically significant differences (P<0.05), and a higher percentage of pulp canal stenosis, without a statistically significant difference. Grey and White MTA presented high levels of clinical and radiographic success. Although the present study showed evidence of a very good biologic response with both types of MTA, Grey MTA showed significantly higher number of dentine bridge formation than White MTA. Copyright © 2010 Elsevier Ltd. All rights reserved.

  19. 'Does my Diet Affect my Perfume?' Identification and Quantification of Cuticular Compounds in Five Drosophila melanogaster Strains Maintained over 300 Generations on Different Diets.

    PubMed

    Pavković-Lučić, Sofija; Todosijević, Marina; Savić, Tatjana; Vajs, Vlatka; Trajković, Jelena; Anđelković, Boban; Lučić, Luka; Krstić, Gordana; Makarov, Slobodan; Tomić, Vladimir; Miličić, Dragana; Vujisić, Ljubodrag

    2016-02-01

    Cuticular hydrocarbons (CHCs) in Drosophila melanogaster represent the basis of chemical communication being involved in many important biological functions. The aim of this study was to characterize chemical composition and variation of cuticular profiles in five D. melanogaster strains. These strains were reared for approximately 300 generations on five diets: standard cornmeal medium and substrates prepared with apple, banana, tomato, and carrot. Differences in quantity and/or quality in CHCs were assumed as a result of activation of different metabolic pathways involved in food digestion and adaptations to the particular diet type. In total, independently of sex and strain, 66 chemical compounds were identified. In females of all strains, 60 compounds were identified, while, in males, 47 compounds were extracted. Certain new chemical compounds for D. melanogaster were found. MANOVA confirmed that CHC amounts significantly depend on sex and substrates, as well as on their interactions. Discriminant analysis revealed that flies belonging to 'apple' and 'carrot' strains exhibited the most noticeable differences in CHC repertoires. A non-hydrocarbon pheromone, cis-vaccenyl acetate (cVA) also contributed to the variation in the pheromone bouquet among the strains. Variability detected in CHCs and cVA may be used in the explanation of differences in mating behaviour previously determined in analyzed fly strains. Copyright © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  20. Investigation of increased listeriosis revealed two fishery production plants with persistent Listeria contamination in Finland in 2010.

    PubMed

    Nakari, U-M; Rantala, L; Pihlajasaari, A; Toikkanen, S; Johansson, T; Hellsten, C; Raulo, S M; Kuusi, M; Siitonen, A; Rimhanen-Finne, R

    2014-11-01

    In 2010, a marked increase in listeriosis incidence was observed in Finland. Listeria monocytogenes PFGE profile 96 was responsible for one-fifth of the reported cases and a cluster of PFGE profile 62 was also detected. Investigations revealed two fishery production plants with persistent Listeria contamination. It appears likely that the plants were at least partly responsible for the increase of listeriosis. Epidemiological investigation revealed that 57% (31/54) of cases with underlying immunosuppressive condition or medication reported eating gravad or cold-smoked fish. Two public notices were issued by THL and Evira informing which groups were most at risk from the effects of listeriosis and should therefore be cautious in consuming certain products. Systematic sampling of foods and adequate epidemiological investigation methods are required to identify the sources of Listeria infections. Continuous control measures at fishery production plants producing risk products are essential.

  1. Flexor tendon repair with a knotless, bidirectional barbed suture: an in vivo biomechanical analysis.

    PubMed

    Maddox, Grady E; Ludwig, Jonathan; Craig, Eric R; Woods, David; Joiner, Aaron; Chaudhari, Nilesh; Killingsworth, Cheryl; Siegal, Gene P; Eberhardt, Alan; Ponce, Brent

    2015-05-01

    To compare and analyze biomechanical properties and histological characteristics of flexor tendons either repaired by a 4-strand modified Kessler technique or using barbed suture with a knotless repair technique in an in vivo model. A total of 25 chickens underwent surgical transection of the flexor digitorum profundus tendon followed by either a 4-strand Kessler repair or a knotless repair with barbed suture. Chickens were randomly assigned to 1 of 3 groups with various postoperative times to death. Harvested tendons were subjected to biomechanical testing or histologic analysis. Harvested tendons revealed failures in 25% of knotless repairs (8 of 32) and 8% of 4-strand Kessler repairs (2 of 24). Biomechanical testing revealed no significant difference in tensile strength between 4-strand Kessler and barbed repairs; however, this lack of difference may be attributed to lower statistical power. We noted a trend toward a gradual decrease in strength over time for barbed repairs, whereas we noticed the opposite for the 4-strand Kessler repairs. Mode of failure during testing differed between repair types. The barbed repairs tended toward suture breakage as opposed to 4-strand Kessler repairs, which demonstrated suture pullout. Histological analysis identified no difference in the degree of inflammation or fibrosis; however, there was a vigorous foreign body reaction around the 4-strand Kessler repair and no such response around the barbed repairs. In this model, knotless barbed repairs trended toward higher in vivo failure rates and biomechanical inferiority under physiologic conditions, with each repair technique differing in mode of failure and respective histologic reaction. We are unable to recommend the use of knotless barbed repair over the 4-strand modified Kessler technique. For the repair techniques tested, surgeons should prefer standard Kessler repairs over the described knotless technique with barbed suture. Copyright © 2015 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  2. Audio steganography by amplitude or phase modification

    NASA Astrophysics Data System (ADS)

    Gopalan, Kaliappan; Wenndt, Stanley J.; Adams, Scott F.; Haddad, Darren M.

    2003-06-01

    This paper presents the results of embedding short covert message utterances on a host, or cover, utterance by modifying the phase or amplitude of perceptually masked or significant regions of the host. In the first method, the absolute phase at selected, perceptually masked frequency indices was changed to fixed, covert data-dependent values. Embedded bits were retrieved at the receiver from the phase at the selected frequency indices. Tests on embedding a GSM-coded covert utterance on clean and noisy host utterances showed no noticeable difference in the stego compared to the hosts in speech quality or spectrogram. A bit error rate of 2 out of 2800 was observed for a clean host utterance while no error occurred for a noisy host. In the second method, the absolute phase of 10 or fewer perceptually significant points in the host was set in accordance with covert data. This resulted in a stego with successful data retrieval and a slightly noticeable degradation in speech quality. Modifying the amplitude of perceptually significant points caused perceptible differences in the stego even with small changes of amplitude made at five points per frame. Finally, the stego obtained by altering the amplitude at perceptually masked points showed barely noticeable differences and excellent data recovery.

  3. Trench Parallel Bouguer Anomaly (TPBA): A robust measure for statically detecting asperities along the forearc of subduction zones

    NASA Astrophysics Data System (ADS)

    Raeesi, M.

    2009-05-01

    During 1970s some researchers noticed that large earthquakes occur repeatedly at the same locations. These observations led to the asperity hypothesis. At the same times some researchers noticed that there was a relationship between the location of great interplate earthquakes and the submarine structures, basins in particular, over the rupture area in the forearc regions. Despite these observations there was no comprehensive and reliable hypothesis explaining the relationship. There were numerous cons and pros to the various hypotheses given in this regard. In their pioneering study, Song and Simons (2003) approached the problem using gravity data. This was a turning point in seismology. Although their approach was correct, appropriate gravity anomaly had to be used in order to reveal the location and extent of the asperities. Following the method of Song and Simons (2003) but using the Bouguer gravity anomaly that we called "Trench Parallel Bouguer Anomaly", TPBA, we found strong, logical, and convincing relation between the TPBA-derived asperities and the slip distribution as well as earthquake distribution, foreshocks and aftershocks in particular. Various parameters with different levels of importance are known that affect the contact between the subducting and the overriding plates, We found that the TPBA can show which are the important factors. Because the TPBA-derived asperities are based on static physical properties (gravity and elevation), they do not suffer from instabilities due to the trade-offs, as it happens for asperities derived in dynamic studies such as waveform inversion. Comparison of the TPBA-derived asperities with rupture processes of the well-studied great earthquakes, reveals the high level of accuracy of the TPBA. This new measure opens a forensic viewpoint on the rupture process along the subduction zones. The TPBA reveals the reason behind 9+ earthquakes and it explains where and why they occur. The TPBA reveals the areas that can generate tsunami earthquakes. It gives a logical dimension to the foreshock and aftershock distributions. Using the TPBA, we can derive the scenarios for the early 20th century great earthquakes for which limited data is available. We present cases from Aleutian and South America subduction zones. The TPBA explains why there should be no great earthquake in the down-dip of Shumagin, but that there should be a major tsunami earthquake for its up-dip. Our evidences suggest that the process has already started. We give numerous examples for South America, Aleutian-Alaska, and Kurile-Kamchatka subduction zones and we also look at Cascadia. Despite the possible various applications of the new measure, here we draw the attention to its most important application - the detection of critical asperities. Supplied with this new measure, in addition to the available seismological data, seismologists should be able to detect the critical asperities and follow the evolving rupture process. This paves the way for revealing systematically the great interplate earthquakes.

  4. Experimental Results of Multiple Scattering.

    DTIC Science & Technology

    1980-07-01

    error is seen to be less for targets with smaller IS()I/IS(O)Iratio like the softer particles made from expanded polystyrene and larger for harder...optical spectrum, we also notice marked differences from the P, Q plots of dylite ( expanded polystyrene ) particles in preceding sections. It was...spheres made of expanded polystyrene . As X is continuously varied for the display of if(e) , we notice a fairly symmetrical intensity profile about X = 8/2

  5. Mechanism of grape seeds extract protection against paracetamol renal cortical damage in male Albino rats.

    PubMed

    Abdel-Hafez, S M N; Rifaai, R A; Abd Elzaher, W Y

    2017-01-01

    The aim of the study was to assess the possible protective role of grape seeds extract (GSE) in ameliorating the toxic effects of paracetamol overdose on the rat renal cortical tissue. Paracetamol is one of the widely used non-steroidal anti-inflammatory drugs (NSAIDs). Unfortunately, it was reported as the most common cause of toxic ingestion in the world. Grape seeds extract (GSE) is known to have a strong antioxidant and anti-inflammatory properties. The rats were divided into 4 groups; control group, GSE group, paracetamol group and GSE with paracetamol group. Kidney specimens were processed for biochemical, histological and immunohisto-chemical studies. The study showed marked biological changes in the form of significant increase in serum urea and creatinine levels with significant decrease in renal superoxide dismutase with paracetamol group. Furthermore, Proximal (PCT) and distal convoluted tubules showed marked degeneration, dense nuclear staining, cytoplasmic vacuolization, and partial loss of the brush borders. Most tubules were dilated, irregular and were filled with hyaline casts. PCT and DCT showed less PAS reaction and more COX-2 and caspase expression if compared with the control and the GSE groups. Concomitant administration of grape seeds extract with paracetamol revealed a noticeable amelioration of these biochemical and histological changes. Proximal and distal convoluted tubules showed less PAS reaction and more COX2 and caspase expression if compared with the control and the GSE. Concomitant administration of GSE with paracetamol revealed a noticeable amelioration of these biochemical and histological changes. Grape seeds extract provided biochemical and histo-pathological improvement in paracetamol induced renal cortical toxicity. These findings revealed that this improvement was associated with a decrease in oxidative damage and apoptosis (Tab. 1, Fig. 7, Ref. 55).

  6. Two-Mirror Schwarzschild Aplanats: Basic Relations

    NASA Astrophysics Data System (ADS)

    Terebizh, V. Yu.

    2005-02-01

    The theory of aplanatic two-mirror telescopes developed by Karl Schwarzschild in 1905 is shown to lead to a unified description of both prefocal and postfocal systems. The class of surfaces in the ZEMAX optical program has been properly extended to ascertain the image quality in exact Schwarzschild aplanats. A comparison of Schwarzschild aplanats with approximate Ritchey-Chrétien and Gregory-Maksutov aplanatic telescopes reveals a noticeable advantage of the former at the system’s fast focal ratio.

  7. Electrodeposition and Characterization of Ni-Al2O3 Nanocomposite Coatings on Steel

    NASA Astrophysics Data System (ADS)

    Akhtar, Khalida; Khan, Zia Ullah; Gul, Muhammad; Zubair, Naila; Shah, Syed Sajjad Ali

    2018-05-01

    Monodispersed alumina particles were synthesized by the homogeneous precipitation under reflux boiling. The particles were employed as reinforcement additives in the electrodeposited Ni-Al2O3 composite coatings on steel. The deposited pure Ni and Ni-Al2O3 composite coatings were analyzed by SEM, XRD, and microhardness tester. The wear resistance and friction coefficient of the coated samples were determined by using a ball-on-disk tribometer. Furthermore, XRD analysis showed that coating temperature and the presence of particles in the deposited coatings had a noticeable effect on the preferred orientation of the crystalline faces of the nickel grains. Significant differences were noted in the texture coefficient of the pure Ni and Ni-Al2O3 composite coatings produced at different temperatures. These differences were attributed to the changes in the microstructure of the matrix caused by the embedded Al2O3 particles. Results revealed that wear resistance and the friction coefficient were turned out to be higher and smaller, respectively, for the composite coatings as compared to pure Ni coating at a given sliding distance. It was noted that the corrosion resistance of these specimens increased in the following order: bare substrate < pure Ni coating < Ni-Al2O3 nanocomposite coatings.

  8. Investigation of Legal Criteria Governing Notice Requirements and Oral Change Order Disputes

    DTIC Science & Technology

    1989-05-01

    compared waiver to equitable estoppel . The doctrine of estoppel prevents the owner from insisting upon strict compliance of the contract requirements...refusal to enforce forfeiture has been based on the doctrines of waiver or estoppel . That is to say, the courts have found that the owner had committed...his right to insist on notice. The terms waiver and estoppel are closely related. These will first be defined and their similarities and differences

  9. Comparison of hydrocephalus appearance at spinaldysraphia.

    PubMed

    Elshani, Besnik; Lenjani, Basri

    2013-01-01

    Congenital malformation of spinal dysraphism followed by hydrocephalus are phenomenon reveals during intrauterine child growth. Prime objective of this work was to present Comparison of hydrocephalus appearance at spinal dysraphism respectively at its meningocele and myelomeningocele forms in Neurosurgery Clinic in UCC in Prishtina. It is perfected with retrospective and prospective method precisely of its epidemiologic part summarizing notices from patients' histories which in 2000-2006 are hospitalized in Neurosurgery Clinic from (QFLPK)--Pediatric Clinic and Children Box (Department)--Gynecology Clinic and from Sanitary Regional Center throughout Kosova. Our study objects were two groups, as the first group 90 patients with spinal dysraphism where neurosurgery operations were done and classified types of dysraphism. At myelomeningocele hydrocephalus has dominated and in a percent of appearance and as acute of its active form was 97% of hydrocephalus form where subjected to cerebrospinal liquid derivation with ventriculo -peritoneal shunt in comparison with meningocele we do not have involvation of spinal nerve element, hydrocephalus takes active form with intervention indication in 60% of cases. Reflection in shown deficit aspect is totally different at myelomeningoceles where lower paraplegia dominate more than paraparesis. The second patient operative technique developed by hydrocephalus with neurosurgical intervention indication has to do with placing of (VP) ventriculo- peritoneal system (shant) at myelomeningoceles with hydrocephalus 58 cases and 12 cases meningoceles with hydrocephalus. Post operative meningitis (shant meningitis): from 70 operated cases of hydrocephalus with spinal dysraphism shunts complications from all types are just cases. Finally that appearance of hydrocephalus compared at spinal dysraphism dominate at myellomeningoceles as in notice time aspect, it is persisting and further acute, with vital motivation for neurosurgical intervention.

  10. Unusual Variability of the Drosophila Melanogaster Ref(2)p Protein Which Controls the Multiplication of Sigma Rhabdovirus

    PubMed Central

    Dru, P.; Bras, F.; Dezelee, S.; Gay, P.; Petitjean, A. M.; Pierre-Deneubourg, A.; Teninges, D.; Contamine, D.

    1993-01-01

    The ref(2)P gene of Drosophila melanogaster was identified by the discovery of two alleles, P(o) and P(p), respectively, permissive and restrictive for sigma rhabdovirus multiplication. A surprising variability of this gene was first noticed by the observation of size differences between the transcripts of permissive and restrictive alleles. In this paper, another restrictive allele, P(n), clearly distinct from P(p), is described: it exhibits a weaker antiviral effect than P(p) and differs from P(p) by its molecular structure. Five types of alleles were distinguished on the basis of their molecular structure, as revealed by S1 nuclease analysis of 17 D. melanogaster strains; three alleles were permissive and two restrictive. Comparison of the sequences of four haplotypes revealed numerous point mutations, two deletions (21 and 24 bp) and a complex event involving a 3-bp deletion, all affected the coding region. The unusual variability of the ref(2)P locus was confirmed by the high ratio of amino acid replacements to synonymous mutations (7:1), as compared to that of other genes, such as the Adh (2:42). Nevertheless, nucleotide sequence comparison with the Drosophila erecta ref(2)P gene shows that selective pressures are exerted to maintain the existence of a functional protein. The effects of this high variability on the ref(2)P protein are discussed in relation to its specific antiviral properties and to its function in D. melanogaster, where it is required for male fertility. PMID:8462852

  11. Rapid convergent evolution in wild crickets.

    PubMed

    Pascoal, Sonia; Cezard, Timothee; Eik-Nes, Aasta; Gharbi, Karim; Majewska, Jagoda; Payne, Elizabeth; Ritchie, Michael G; Zuk, Marlene; Bailey, Nathan W

    2014-06-16

    The earliest stages of convergent evolution are difficult to observe in the wild, limiting our understanding of the incipient genomic architecture underlying convergent phenotypes. To address this, we capitalized on a novel trait, flatwing, that arose and proliferated at the start of the 21st century in a population of field crickets (Teleogryllus oceanicus) on the Hawaiian island of Kauai. Flatwing erases sound-producing structures on male forewings. Mutant males cannot sing to attract females, but they are protected from fatal attack by an acoustically orienting parasitoid fly (Ormia ochracea). Two years later, the silent morph appeared on the neighboring island of Oahu. We tested two hypotheses for the evolutionary origin of flatwings in Hawaii: (1) that the silent morph originated on Kauai and subsequently introgressed into Oahu and (2) that flatwing originated independently on each island. Morphometric analysis of male wings revealed that Kauai flatwings almost completely lack typical derived structures, whereas Oahu flatwings retain noticeably more wild-type wing venation. Using standard genetic crosses, we confirmed that the mutation segregates as a single-locus, sex-linked Mendelian trait on both islands. However, genome-wide scans using RAD-seq recovered almost completely distinct markers linked with flatwing on each island. The patterns of allelic association with flatwing on either island reveal different genomic architectures consistent with the timing of two mutational events on the X chromosome. Divergent wing morphologies linked to different loci thus cause identical behavioral outcomes--silence--illustrating the power of selection to rapidly shape convergent adaptations from distinct genomic starting points. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Electrodeposition and codeposition under low gravity/nonconvecting conditions

    NASA Technical Reports Server (NTRS)

    Riley, Clyde; Coble, H. Dwain; Loo, Boon; Benson, Brian; Abi-Akar, Hind

    1987-01-01

    An experimental electrodeposition system was developed for modeling the behavior of inert particles codepositing in an electroplating matrix under low-gravity conditions. The device consists of a Co-electrodeposition cell operating in a convectionless mode (cathode over anode) and containing polystyrene particles with density approximating that of the electroplating solution. Data were obtained in shielded cells at 1 g, and the experiment was duplicated at 0.01 g on a KC-135 flight. No difference was found between convection-free bench experiments and the 0.01 g KC-135 experiments with 0.0900 M CuSO4. Codeposition experiments using 11.8-micron matched-density polystyrene spheres in 1 M CoSO4 have revealed that a noticeable particle gradient is created as the solution density mismatches in the vicinity of the cathode; gentle stirring was required to maintain a homogeneous particle suspension. Cr3C2 dust, which readily disperses at 1 g, tended to coagulate into spherical globules at 0.01 g, when stirred.

  13. Biotin-Avidin ELISA Detection of Grapevine Fanleaf Virus in the Vector Nematode Xiphinema index.

    PubMed

    Esmenjaud, D; Walter, B; Minot, J C; Voisin, R; Cornuet, P

    1993-09-01

    The value of biotin-avidin (B-A) ELISA for the detection of grapevine fanleaf virus (GFLV) in Xiphinema was estimated with field populations and greenhouse subpopulations. Samples consisted of increasing numbers of adults ranging from 1 to 64 in multiples of two. Tests with virus-free X. index populations reared on grapevine and fig plants as negative controls did not reveal a noticeable effect of the host plant. ELISA absorbances of virus-free X. index samples were greater than corresponding absorbances of X. pachtaicum samples. Differences occurred between two X. index field populations from GFLV-infected grapevines in Champagne and Languedoc. In most tests, 1-, 2-, 4-, and 8-nematode samples of virus-free and virus-infected populations, respectively, could not be separated. Consequently, B-A ELISA was not a reliable method for GFLV detection in samples of less than 10 X. index adults, but comparison of the absorbances obtained with increasing numbers may allow differentiation of the viral infectious potential of several populations.

  14. An Adiabatic Quantum Algorithm for Determining Gracefulness of a Graph

    NASA Astrophysics Data System (ADS)

    Hosseini, Sayed Mohammad; Davoudi Darareh, Mahdi; Janbaz, Shahrooz; Zaghian, Ali

    2017-07-01

    Graph labelling is one of the noticed contexts in combinatorics and graph theory. Graceful labelling for a graph G with e edges, is to label the vertices of G with 0, 1, ℒ, e such that, if we specify to each edge the difference value between its two ends, then any of 1, 2, ℒ, e appears exactly once as an edge label. For a given graph, there are still few efficient classical algorithms that determine either it is graceful or not, even for trees - as a well-known class of graphs. In this paper, we introduce an adiabatic quantum algorithm, which for a graceful graph G finds a graceful labelling. Also, this algorithm can determine if G is not graceful. Numerical simulations of the algorithm reveal that its time complexity has a polynomial behaviour with the problem size up to the range of 15 qubits. A general sufficient condition for a combinatorial optimization problem to have a satisfying adiabatic solution is also derived.

  15. Fragmentation of sea bass populations in the western and eastern Mediterranean as revealed by microsatellite polymorphism.

    PubMed Central

    Bahri-Sfar, L; Lemaire, C; Ben Hassine, O K; Bonhomme, F

    2000-01-01

    We studied the genetic structure at six microsatellite loci of the Mediterranean sea bass (Dicentrarchus labrax) on 19 samples collected from different localities in the western and eastern Mediterranean basins. Significant divergence was found between the two basins. The distance tree showed two separate clusters of populations which matched well with geography, with the noticeable exception of one Egyptian sample which grouped within the western clade, a fact attributable to the introduction of aquaculture broodstock. No heterogeneity was observed within the western basin (theta = 0.0014 and n.s.). However, a significant level of differentiation was found among samples of the eastern Mediterranean (theta = 0.026 and p < 0.001). These results match with water currents but probably not with the dispersal abilities of this fish species. We thus hypothesize that selective forces are at play which limit long-range dispersal, a fact to be taken into account in the debate about speciation processes in the marine environment. PMID:10853737

  16. Examination of thermal comfort in a hospital using PMV-PPD model.

    PubMed

    Pourshaghaghy, A; Omidvari, M

    2012-11-01

    In this study, the performance of air conditioning system and the level of thermal comfort are determined in a state hospital located in Kermanshah city in the west of Iran in winter and summer using the Predicted Mean Vote (PMV) model which has been presented by ISO-7730 (2005). The Predicted Mean Vote (PMV) and the Predicted Percentage Dissatisfied (PPD) indices were computed using the data acquired from the experimental measurements performed in the building. The results showed that the values of PMV in some parts of the building, both for men and women, are not within the standard acceptable range defined by ISO. It was found that the most thermal problems in winter occur in morning work shift, and the worst thermal conditions in summer occur in noon work shift. The t-test results revealed that there is no noticeable difference between the thermal conditions of some rooms and those of the surroundings. Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

  17. Precipitable water: Its linear retrieval using leaps and bounds procedure and its global distribution from SEASAT SMMR data

    NASA Technical Reports Server (NTRS)

    Pandey, P. C.

    1982-01-01

    Eight subsets using two to five frequencies of the SEASAT scanning multichannel microwave radiometer are examined to determine their potential in the retrieval of atmospheric water vapor content. Analysis indicates that the information concerning the 18 and 21 GHz channels are optimum for water vapor retrieval. A comparison with radiosonde observations gave an rms accuracy of approximately 0.40 g sq cm. The rms accuracy of precipitable water using different subsets was within 10 percent. Global maps of precipitable water over oceans using two and five channel retrieval (average of two and five channel retrieval) are given. Study of these maps reveals the possibility of global moisture distribution associated with oceanic currents and large scale general circulation in the atmosphere. A stable feature of the large scale circulation is noticed. The precipitable water is maximum over the Bay of Bengal and in the North Pacific over the Kuroshio current and shows a general latitudinal pattern.

  18. Characteristics of health-promoting schools from Iranian adolescents' point of view.

    PubMed

    Shahhosseini, Zohreh; Simbar, Masoumeh; Ramezankhani, Ali

    2016-05-01

    Although characteristics of health-promoting schools are mentioned in the World Health Organization guidelines, different countries need to design more details of indicators for assessing these schools according to their social and cultural context. The aim of this study was to investigate characteristics of health-promoting schools from Iranian adolescent girls' point of view. In this cross-sectional study, 2010 middle school and high school female adolescents were selected from randomly selected schools in Mazandaran province, Iran. They completed a self-completion questionnaire around their views about characteristics of health- promoting schools. Data were analyzed using descriptive statistics and an independent t-test. It is revealed that from Iranian adolescents' point of view the most important feature of health-promoting schools was the schools with no stressful exams and where notices are kindly given to students for their mistakes. The results suggest that there is a need for more measurable standards of health-promoting schools based on the socio-cultural context of both developing and developed countries.

  19. [The role of oxidative stress in pathogenesis of GBS].

    PubMed

    Dogonadze, S I; Ninua, N G; Gordeziani, M G; Kavlashvili, M S; Sanikidze, T V

    2006-11-01

    Axon degeneration accompanying its demielinization is a main course of neurological insufficiency typical for GBS. The mechanisms of axon degeneration, considered as the secondary result of serve inflammation are not established. We aimed to determine the role of oxidative metabolism in viral polyneuropathy pathogenesis. The activity of pro- and antioxidant systems of the body was studied by electron paramagnetic resonance (EPR) method. In blood and cerebrospinal fluid the intensive EPR signals of nitric oxide (NO), complexes of NO with nonhemic iron (HbNO), lypo- and superoxide radicals content noticeably increases, the signals of free Mn2+ and Fe2+ revealed, the activity of blood antioxidant enzymes, ceruloplasmin and katalasa increases (by 60%), superoxidedismitase's and glutation reductases activity decreases (by 20% and 70% correspondingly). It was considered, that inflammatory damage of nervous system induced by different infectious stimulus is initiated by activated immune cell proinflamatory agents (reactive oxygen and nitrogen species). Subsequently the oxidative stress, as result of accumulation of generators of reactive oxygen species, disordered intracellular metabolism products, contributes to axon demielinization and degeneration.

  20. Applying the Kanban method in problem-based project work: a case study in a manufacturing engineering bachelor's programme at Aalborg University Copenhagen

    NASA Astrophysics Data System (ADS)

    Balve, Patrick; Krüger, Volker; Tolstrup Sørensen, Lene

    2017-11-01

    Problem-based learning (PBL) has proven to be highly effective for educating students in an active and self-motivated manner in various disciplines. Student projects carried out following PBL principles are very dynamic and carry a high level of uncertainty, both conditions under which agile project management approaches are assumed to be highly supportive. The paper describes an empirical case study carried out at Aalborg University Copenhagen involving students from two different semesters of a Bachelor of Science programme. While executing the study, compelling examples of how PBL and the agile project management method Kanban blend could be identified. A final survey reveals that applying Kanban produces noticeable improvements with respect to creating, assigning and coordinating project tasks. Other improvements were found in group communication, knowledge about the work progress with regards to both the individual and the collective and the students' way of continuously improving their own teamwork.

  1. Screening preschool children for fine motor skills: environmental influence.

    PubMed

    Comuk-Balci, Nilay; Bayoglu, Birgul; Tekindal, Agah; Kerem-Gunel, Mintaze; Anlar, Banu

    2016-03-01

    [Purpose] The aim of this study was to investigate the influence of gender and family factors on performance in the fine motor domain of the Denver II developmental screening test. [Subjects and Methods] Data were obtained from 2038 healthy children, 999 boys (49%) and 1039 girls (51%) in four age groups: 0-24 months (57%), 25-40 months (21.1%), 41-56 months (10.4%), and 57-82 months (11.5%). [Results] Female gender, higher maternal age, especially in children older than 24 months, and higher maternal education were associated with earlier accomplishment of fine motor items. Higher socioeconomic status was correlated with fine motor skills more noticeably at young ages. [Conclusion] The results of this study support the role of environmental factors in the interpretation of fine motor test results and point to target groups for intervention, such as infants in the low socioeconomic group and preschool children of less educated mothers. Studies in different populations may reveal particular patterns that affect child development.

  2. Enhancement of low pressure cold sprayed copper coating adhesion by laser texturing on aluminum substrates

    NASA Astrophysics Data System (ADS)

    Knapp, Wolfgang; Gillet, Vincent; Courant, Bruno; Aubignat, Emilie; Costil, Sophie; Langlade, Cécile

    2017-02-01

    Surface pre-treatment is fundamental in thermal spraying processes to obtain a sufficient bonding strength between substrate and coating. Different pre-treatments can be used, mostly grit-blasting for current industrial applications. This study is focused on Cu-Al2O3 coatings obtained by Low Pressure Cold Spray on AW5083 aluminum alloy substrate. Bonding strength is measured by tensile adhesion test, while deposition efficiency is measured. Substrates are textured by laser, using a pattern of equally spaced grooves with almost constant diameter and variations of depth. Results show that bonding strength is improved up to +81% compared to non-treated substrate, while deposition efficiency remains constant. The study of the samples after rupture reveals a modification of the failure mode, from mixed failure to cohesive failure. A modification of crack propagation is also noticed, the shape of laser textured grooves induces a deviation of cracks inside the coating instead of following the interface between the layers.

  3. Surface and magnetic characteristics of Ni-Mn-Ga/Si (100) thin film

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kumar, S. Vinodh; Pandyan, R. Kodi; Mahendran, M., E-mail: manickam-mahendran@tce.edu, E-mail: perialangulam@gmail.com

    2016-05-23

    Polycrystalline Ni-Mn-Ga thin films have been deposited on Si (100) substrate with different film thickness. The influence of film thickness on the phase structure and magnetic domain of the films has been examined by scanning electron microscope, atomic force microscopy and magnetic force microscopy. Analysis of structural parameters indicates that the film at lower thickness exhibits the coexistence of both austenite and martensite phase, whereas at higher thickness L1{sub 2} cubic non magnetic phase is noticed. The grains size and the surface roughness increase along with the film thickness and attain the maximum of 45 nm and 34.96 nm, respectively.more » At lower film thickness, the magnetic stripe domain is found like maze pattern with dark and bright images, while at higher thickness the absence of stripe domains is observed. The magnetic results reveal that the films strongly depend on their phase structure and microstructure which influence by the film thickness.« less

  4. The effect of left-right reversal on film: Watching Kurosawa reversed

    PubMed Central

    Bertamini, Marco; Bode, Carole; Bruno, Nicola

    2011-01-01

    The mirror reversal of an image is subtly different from the original. Often such change goes unnoticed in pictures, although it can affect preference. For the first time we studied the effect of mirror reversal of feature films. People watched Yojimbo or Sanjuro in a cinema, both classic films by Akira Kurosawa. They knew that this was a study and filled out a questionnaire. On one day Yojimbo was shown in its original orientation, and on another day the film was mirror reversed. Sanjuro was shown reversed on one day and non-reversed on another day. Viewers did not notice the reversal, even when they had seen the film before and considered themselves fans of Kurosawa. We compared this with estimates from a survey. In addition, the question about the use of space (scenography) revealed that although people who had seen the film before gave higher ratings compared with those who had not, this was only true when the film was not reversed. PMID:23145243

  5. Spaceflight Effects on Hemopoiesis of Lower Vertebrates Flown on Foton-M2

    NASA Technical Reports Server (NTRS)

    Domaratskaya, E. I.; Payushina, O. V.; Butorina, M. N.; Nikonova, T. M.; Grigorian, E. N.; Mitashov, V. I.; Tairbekov, M. G.; Almeida, E.; Khrushchov, N. G.

    2006-01-01

    Intact and operated newts Pleumdeles waltl flown on Foton-M2 for 16 days were used to study the effects of spaceflight as well as tail amputation and lensectomy on their hemopoiesis. The flight did not produce noticeable changes in the peripheral blood of nonoperated newts. However, in operated animals, the number of lymphocytes increased whereas that of neutrophils decreased. There were no morphological differences in hemopoietic organs (liver and spleen) between flown non-operated and operated animals or their controls. However, in both non-operated and operated newts the liver weight and the number of hemopoietic cells in it increased. In contrast to nonoperated newts, space-flown mammals typically showed significant changes in blood cell counts. Experiments with BrdU incorporation revealed labeled cells in the hemopoietic area of the liver as well as in blood and spleen. This observation gives evidence that the BrdU label can be used to study proliferation of hemopoietic cells.

  6. Metabolomics analysis of rice responses to salinity stress revealed elevation of serotonin, and gentisic acid levels in leaves of tolerant varieties.

    PubMed

    Gupta, Poulami; De, Bratati

    2017-07-03

    A GC-MS based analytical approach was undertaken to understand the metabolomic responses of seedlings of 2 salt sensitive (Sujala and MTU 7029) and 2 tolerant varieties (Bhutnath, and Nonabokra) of indica rice (Oryza sativa L.) to NaCl induced stress. The 4 varieties responded differently to NaCl treatment with respect to the conserved primary metabolites (sugars, polyols, amino acids, organic acids and certain purine derivatives) of the leaf of rice seedlings. However, there were significant differences in salt induced production of chorismic acid derivatives. Serotonin level was increased in both the salt tolerant varieties in response to NaCl induced stress. In both the salt tolerant varieties, increased production of the signaling molecule gentisic acid in response to NaCl treatment was noticed. Salt tolerant varieties also produced increased level of ferulic acid and vanillic acid. In the salt sensitive varieties, cinnamic acid derivatives, 4-hydroxycinnamic acid (in Sujala) and 4-hydroxybenzoic acid (in MTU 7029), were elevated in the leaves. So increased production of the 2 signaling molecules serotonin and gentisic acid may be considered as 2 important biomarker compounds produced in tolerant varieties contributing toward NaCl tolerance.

  7. Pea protein concentrate in diets for sharpsnout sea bream (Diplodus puntazzo): effects on growth and health status.

    PubMed

    Nogales-Mérida, Silvia; Tomás-Vidal, Ana; Moñino-López, Andrés; Jover-Cerdá, Miguel; Martínez-Llorens, Silvia

    2016-12-01

    Four diets for sharpsnout sea bream juveniles (14 g body weight) with four levels of air-processed pea protein concentrate (PPC) (0, 160, 320 and 487 g/kg diet) were tested in triplicate. The experimental diets were isonitrogenous (43% crude protein) and isolipidic (19% ether extract) and the fish were fed to satiation twice a day. After 125 d, fish growth was diminished by the inclusion of PPC. Feed conversion did not show significant differences in any treatment. Neither the body analyses nor the protein and individual essential amino acid retention efficiencies were affected by the inclusion of PPC in the diet. However, histological gut examinations revealed noticeable differences. Fish fed the diet with the highest inclusion level of PPC presented the longest villous length and the most goblet cells, and the width of the lamina propria increased in the anterior intestine. Although no negative changes in nutritive parameters were detected, these alterations might affect nutrient transport, with negative consequences for fish growth. It was concluded that the PPC in the amounts tested here is an inappropriate substitute for fishmeal in diets for sharpsnout sea bream juveniles.

  8. Emission of OH* and CO2* during the high-temperature oxidation of acetone in reflected shock waves

    NASA Astrophysics Data System (ADS)

    Tereza, A. M.; Smirnov, V. N.; Vlasov, P. A.; Shumova, V. V.; Garmash, A. A.

    2018-01-01

    Experimental and kinetic modeling study of the ignition of a stoichiometric mixture of acetone with oxygen diluted by argon was carried out behind reflected shock waves within the temperature range of 1350-1810 K for the total mixture concentration [M 50] ~ 10-5 mol/cm3. Emission signals were recorded simultaneously for three different wavelengths: OH* (λ = 308 nm) and {{{CO}}}2* (λ1 = 365 nm; λ2 = 451 nm). It was revealed that the time it takes to reach the maximum of emission of OH* and {{{CO}}}2* is practically the same over the whole temperature range. At the same time, the emission profiles of {{{CO}}}2* after the maximum was attained, recorded at λ2 = 451 nm, differ noticeably from the profiles recorded at λ1 = 365 nm. For numerical modeling of the emission profiles of OH* and {{{CO}}}2* , the corresponding sets of excitation and quenching reactions available in the literature were used. In the course of our numerical simulations we succeeded in good agreement of our own experimental and simulation results on acetone ignition and the results available in the literature for conditions under consideration.

  9. Somatic focus/awareness: Relationship to negative affect and pain in chronic pain patients

    PubMed Central

    O’Brien, Erin M.; Atchison, James W.; Gremillion, Henry A.; Waxenberg, Lori B.; Robinson, Michael E.

    2009-01-01

    Somatic focus refers to the tendency to notice and report physical symptoms, and has been investigated in relation to chronically painful conditions. This study investigated the relationship between somatic focus, as measured by the Pennebaker Inventory of Limbic Languidness (PILL), negative affect and pain. A secondary purpose of the present study was to examine sex differences in these relationships. Participants included 280 chronic pain patients (69.6% females, 88.9% Caucasian), who completed a battery of self-report measures on somatic focus, pain, negative affect, coping, and dysfunction. Results for the overall sample revealed that the PILL shares considerable variance with measures of negative affect, particularly with the physiological components of anxiety and depression. When the results were analyzed separately for male and female patients, it was found that several components of negative affect and cognitive factors play a stronger role in predicting somatic focus among men compared to women. Additional analyses then examined whether somatic focus was predictive of male and female patients’ pain reports. Results indicated that somatic focus explained a small, but unique amount of variance in female patients’ pain reports, which differed from the relationship observed among male patients. PMID:17524684

  10. Effect of Co-60 gamma radiation on optical, dielectric and mechanical properties of strontium L-ascorbate hexahydrate NLO crystal

    NASA Astrophysics Data System (ADS)

    Dileep, M. S.; Suresh Kumar, H. M.

    2018-04-01

    A potentially useful nonlinear optical semi-organic single crystal of strontium L-ascorbate hexahydrate (SLAH) was grown by solution growth slow evaporation technique at room temperature. The grown crystal is semi transparent, yellowish in color with monoclinic crystal system having space group P21 and is stable up to 198 °C. Further, SLAH crystals were irradiated with gamma rays produced by 60Co with different doses of 10 KGy, 30 KGy and 50 KGy at room temperature and then studied the effect of gamma-rays on dielectric properties, optical absorption, microhardness and SHG efficiency. The absorption study reveals that the absorbance of the grown crystal is appeared to be low throughout the visible region with a lower cutoff wavelength of 277 nm and these parameters are not affected upon gamma irradiation. The luminescence intensity of the crystal is also not affected by the irradiation. There is noticeable changes were observed in dielectric properties and hardness of the materials for different doses of gamma irradiation. The second harmonic generation (SHG) efficiency of the grown crystal is 0.54 times that of the KDP crystal and is decreased moderately by increasing the dosage of gamma irradiation.

  11. Clinically applied procedures for human ovarian tissue cryopreservation result in different levels of efficacy and efficiency.

    PubMed

    Bastings, Lobke; Westphal, Johan R; Beerendonk, Catharina C M; Bekkers, Ruud L M; Zusterzeel, Petra L M; Hendriks, Jan C M; Braat, Didi D M; Peek, Ronald

    2016-12-01

    Different protocols are being used worldwide for the cryopreservation of human ovarian tissue for fertility preservation purposes. The efficiency and efficacy of the majority of these protocols has not been extensively evaluated, possibly resulting in sub-optimally cryopreserved ovarian tissue. To address the impact of this issue, we assessed the effects of two clinically successful human ovarian tissue slow-freezing cryopreservation procedures on the quality of the cryopreserved tissue. To differentiate between cryopreservation ( C ) versus thawing ( T ) related effects, four combinations of these two (A and B) very different cryopreservation/thawing protocols (A C A T , A C B T , B C A T , B C B T ) were studied. Before and after cryopreservation and thawing, the percentage of living and morphologically normal follicles, as well as the overall tissue viability, was assessed. Our experiments revealed that the choice of the cryopreservation protocol noticeably affected the overall tissue viability and percentage of living follicles, with a higher viability after protocol B C when compared to A C . No statistically significant differences in tissue viability were observed between the two thawing protocols, but thawing protocol B T required considerably more human effort and materials than thawing protocol A T . Tissue morphology was best retained using the B C A T combination. Our results indicate that extensive and systematical evaluation of clinically used protocols is warranted.

  12. Influence of surface defects on the tensile strength of carbon fibers

    NASA Astrophysics Data System (ADS)

    Vautard, F.; Dentzer, J.; Nardin, M.; Schultz, J.; Defoort, B.

    2014-12-01

    The mechanical properties of carbon fibers, especially their tensile properties, are affected by internal and surface defects. In order to asses in what extent the generation of surface defects can result in a loss of the mechanical properties, non-surface treated carbon fibers were oxidized with three different surface treatment processes: electro-chemical oxidation, oxidation in nitric acid, and oxidation in oxygen plasma. Different surface topographies and surface chemistries were obtained, as well as different types and densities of surface defects. The density of surface defects was measured with both a physical approach (Raman spectroscopy) and a chemical approach (Active Surface Area). The tensile properties were evaluated by determining the Weibull modulus and the scale parameter of each reference, after measuring the tensile strength for four different gauge lengths. A relationship between the tensile properties and the nature and density of surface defects was noticed, as large defects largely control the value of the tensile strength. When optimized, some oxidation surface treatment processes can generate surface functional groups as well as an increase of the mechanical properties of the fibers, because of the removal of the contamination layer of pyrolytic carbon generated during the carbonization of the polyacrylonitrile precursor. Oxidation in oxygen plasma revealed to be a promising technology for alternative surface treatment processes, as high levels of functionalization were achieved and a slight improvement of the mechanical properties was obtained too.

  13. Impact of PBL and convection parameterization schemes for prediction of severe land-falling Bay of Bengal cyclones using WRF-ARW model

    NASA Astrophysics Data System (ADS)

    Singh, K. S.; Bhaskaran, Prasad K.

    2017-12-01

    This study evaluates the performance of the Advanced Research Weather Research and Forecasting (WRF-ARW) model for prediction of land-falling Bay of Bengal (BoB) tropical cyclones (TCs). Model integration was performed using two-way interactive double nested domains at 27 and 9 km resolutions. The present study comprises two major components. Firstly, the study explores the impact of five different planetary boundary layer (PBL) and six cumulus convection (CC) schemes on seven land-falling BoB TCs. A total of 85 numerical simulations were studied in detail, and the results signify that the model simulated better both the track and intensity by using a combination of Yonsei University (YSU) PBL and the old simplified Arakawa-Schubert CC scheme. Secondly, the study also investigated the model performance based on the best possible combinations of model physics on the real-time forecasts of four BoB cyclones (Phailin, Helen, Lehar, and Madi) that made landfall during 2013 based on another 15 numerical simulations. The predicted mean track error during 2013 was about 71 km, 114 km, 133 km, 148 km, and 130 km respectively from day-1 to day-5. The Root Mean Square Error (RMSE) for Minimum Central Pressure (MCP) was about 6 hPa and the same noticed for Maximum Surface Wind (MSW) was about 4.5 m s-1 noticed during the entire simulation period. In addition the study also reveals that the predicted track errors during 2013 cyclones improved respectively by 43%, 44%, and 52% from day-1 to day-3 as compared to cyclones simulated during the period 2006-2011. The improvements noticed can be attributed due to relatively better quality data that was specified for the initial mean position error (about 48 km) during 2013. Overall the study signifies that the track and intensity forecast for 2013 cyclones using the specified combinations listed in the first part of this study performed relatively better than the other NWP (Numerical Weather Prediction) models, and thereby finds application in real-time forecast.

  14. Perception of color emotions for single colors in red-green defective observers.

    PubMed

    Sato, Keiko; Inoue, Takaaki

    2016-01-01

    It is estimated that inherited red-green color deficiency, which involves both the protan and deutan deficiency types, is common in men. For red-green defective observers, some reddish colors appear desaturated and brownish, unlike those seen by normal observers. Despite its prevalence, few studies have investigated the effects that red-green color deficiency has on the psychological properties of colors (color emotions). The current study investigated the influence of red-green color deficiency on the following six color emotions: cleanliness, freshness, hardness, preference, warmth, and weight. Specifically, this study aimed to: (1) reveal differences between normal and red-green defective observers in rating patterns of six color emotions; (2) examine differences in color emotions related to the three cardinal channels in human color vision; and (3) explore relationships between color emotions and color naming behavior. Thirteen men and 10 women with normal vision and 13 men who were red-green defective performed both a color naming task and an emotion rating task with 32 colors from the Berkeley Color Project (BCP). Results revealed noticeable differences in the cleanliness and hardness ratings between the normal vision observers, particularly in women, and red-green defective observers, which appeared mainly for colors in the orange to cyan range, and in the preference and warmth ratings for colors with cyan and purple hues. Similarly, naming errors also mainly occurred in the cyan colors. A regression analysis that included the three cone-contrasts (i.e., red-green, blue-yellow, and luminance) as predictors significantly accounted for variability in color emotion ratings for the red-green defective observers as much as the normal individuals. Expressly, for warmth ratings, the weight of the red-green opponent channel was significantly lower in color defective observers than in normal participants. In addition, the analyses for individual warmth ratings in the red-green defective group revealed that luminance cone-contrast was a significant predictor in most red-green-defective individuals. Together, these results suggest that red-green defective observers tend to rely on the blue-yellow channel and luminance to compensate for the weak sensitivity of long- and medium-wavelength (L-M) cone-contrasts, when rating color warmth.

  15. Perception of color emotions for single colors in red-green defective observers

    PubMed Central

    Inoue, Takaaki

    2016-01-01

    It is estimated that inherited red-green color deficiency, which involves both the protan and deutan deficiency types, is common in men. For red-green defective observers, some reddish colors appear desaturated and brownish, unlike those seen by normal observers. Despite its prevalence, few studies have investigated the effects that red-green color deficiency has on the psychological properties of colors (color emotions). The current study investigated the influence of red-green color deficiency on the following six color emotions: cleanliness, freshness, hardness, preference, warmth, and weight. Specifically, this study aimed to: (1) reveal differences between normal and red-green defective observers in rating patterns of six color emotions; (2) examine differences in color emotions related to the three cardinal channels in human color vision; and (3) explore relationships between color emotions and color naming behavior. Thirteen men and 10 women with normal vision and 13 men who were red-green defective performed both a color naming task and an emotion rating task with 32 colors from the Berkeley Color Project (BCP). Results revealed noticeable differences in the cleanliness and hardness ratings between the normal vision observers, particularly in women, and red-green defective observers, which appeared mainly for colors in the orange to cyan range, and in the preference and warmth ratings for colors with cyan and purple hues. Similarly, naming errors also mainly occurred in the cyan colors. A regression analysis that included the three cone-contrasts (i.e., red-green, blue-yellow, and luminance) as predictors significantly accounted for variability in color emotion ratings for the red-green defective observers as much as the normal individuals. Expressly, for warmth ratings, the weight of the red-green opponent channel was significantly lower in color defective observers than in normal participants. In addition, the analyses for individual warmth ratings in the red-green defective group revealed that luminance cone-contrast was a significant predictor in most red-green-defective individuals. Together, these results suggest that red-green defective observers tend to rely on the blue-yellow channel and luminance to compensate for the weak sensitivity of long- and medium-wavelength (L-M) cone-contrasts, when rating color warmth. PMID:27957394

  16. Blood-Gene Expression Reveals Reduced Circadian Rhythmicity in Individuals Resistant to Sleep Deprivation

    PubMed Central

    Arnardottir, Erna S.; Nikonova, Elena V.; Shockley, Keith R.; Podtelezhnikov, Alexei A.; Anafi, Ron C.; Tanis, Keith Q.; Maislin, Greg; Stone, David J.; Renger, John J.; Winrow, Christopher J.; Pack, Allan I.

    2014-01-01

    Study Objectives: To address whether changes in gene expression in blood cells with sleep loss are different in individuals resistant and sensitive to sleep deprivation. Design: Blood draws every 4 h during a 3-day study: 24-h normal baseline, 38 h of continuous wakefulness and subsequent recovery sleep, for a total of 19 time-points per subject, with every 2-h psychomotor vigilance task (PVT) assessment when awake. Setting: Sleep laboratory. Participants: Fourteen subjects who were previously identified as behaviorally resistant (n = 7) or sensitive (n = 7) to sleep deprivation by PVT. Intervention: Thirty-eight hours of continuous wakefulness. Measurements and Results: We found 4,481 unique genes with a significant 24-h diurnal rhythm during a normal sleep-wake cycle in blood (false discovery rate [FDR] < 5%). Biological pathways were enriched for biosynthetic processes during sleep. After accounting for circadian effects, two genes (SREBF1 and CPT1A, both involved in lipid metabolism) exhibited small, but significant, linear changes in expression with the duration of sleep deprivation (FDR < 5%). The main change with sleep deprivation was a reduction in the amplitude of the diurnal rhythm of expression of normally cycling probe sets. This reduction was noticeably higher in behaviorally resistant subjects than sensitive subjects, at any given P value. Furthermore, blood cell type enrichment analysis showed that the expression pattern difference between sensitive and resistant subjects is mainly found in cells of myeloid origin, such as monocytes. Conclusion: Individual differences in behavioral effects of sleep deprivation are associated with differences in diurnal amplitude of gene expression for genes that show circadian rhythmicity. Citation: Arnardottir ES, Nikonova EV, Shockley KR, Podtelezhnikov AA, Anafi RC, Tanis KQ, Maislin G, Stone DJ, Renger JJ, Winrow CJ, Pack AI. Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation. SLEEP 2014;37(10):1589-1600. PMID:25197809

  17. Macroalgae Extracts From Antarctica Have Antimicrobial and Anticancer Potential

    PubMed Central

    Martins, Rosiane M.; Nedel, Fernanda; Guimarães, Victoria B. S.; da Silva, Adriana F.; Colepicolo, Pio; de Pereira, Claudio M. P.; Lund, Rafael G.

    2018-01-01

    Background: Macroalgae are sources of bioactive compounds due to the large number of secondary metabolites they synthesize. The Antarctica region is characterized by extreme weather conditions and abundant aggregations of macroalgae. However, current knowledge on their biodiversity and their potential for bio-prospecting is still fledging. This study evaluates the antimicrobial and cytotoxic activity of different extracts of four macroalgae (Cystosphaera jacquinotii, Iridaea cordata, Himantothallus grandifolius, and Pyropia endiviifolia) from the Antarctic region against cancer and non-cancer cell lines. Methods: The antimicrobial activity of macroalgae was evaluated by the broth microdilution method. Extracts were assessed against Staphylococcus aureus ATCC 19095, Enterococcus faecalis ATCC 4083, Escherichia coli ATCC29214, Pseudomonas aeruginosa ATCC 9027, Candida albicans ATCC 62342, and the clinical isolates from the human oral cavity, namely, C. albicans (3), C. parapsilosis, C. glabrata, C. lipolytica, and C. famata. Cytotoxicity against human epidermoid carcinoma (A-431) and mouse embryonic fibroblast (NIH/3T3) cell lines was evaluated with MTT colorimetric assay. Results: An ethyl acetate extract of H. grandifolius showed noticeable antifungal activity against all fungal strains tested, including fluconazole-resistant samples. Cytotoxicity investigation with a cancer cell line revealed that the ethyl acetate extract of I. cordata was highly cytotoxic against A-431 cancer cell line, increasing the inhibitory ratio to 91.1 and 95.6% after 24 and 48 h exposure, respectively, for a concentration of 500 μg mL−1. Most of the algal extracts tested showed little or no cytotoxicity against fibroblasts. Conclusion: Data suggest that macroalgae extracts from Antarctica may represent a source of therapeutic agents. HIGHLIGHTS Different macroalgae samples from Antarctica were collected and the lyophilized biomass of each macroalgae was extracted sequentially with different solventsThe antimicrobial and anticancer potential of macroalgae extracts were evaluatedEthyl acetate extract of H. grandifolius showed noticeable antifungal activity against all the fungal strains tested, including fluconazole-resistant samplesEthyl acetate extract of I. cordata was highly cytotoxic against the A-431 cancer cell lineMost of the algal extracts tested showed little or no cytotoxicity against normal cell lines PMID:29568291

  18. Revealing the Reaction Mechanism of Na–O 2 Batteries using Environmental Transmission Electron Microscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kwak, Won -Jin; Luo, Langli; Jung, Hun -Gi

    Due to its high energy efficiency, sodium-oxygen (Na-O 2) batteries have been extensively studied recently. One of the critical challenges for the development of the Na-O 2 battery is the elucidation of the reaction mechanism, the reaction products, and thestructural and chemical evolution of reaction product as well as their correlation with the battery performance. Herein, in-situ TEM was employed to probe the reaction mechanism and the structural evolution of the discharge products in Na-O 2 batteries. The discharge product is featured by the formation of both cubic and conformal NaO 2. It has been noticed that the impingement ofmore » reaction product (NaO 2) can lead to the coarsening of the particle through coalescence. We also investigated the stability of the discharge product, noticing that the reaction product NaO 2 is stable in the case of solid electrolyte. Here, the present work provide unprecedented insight for the development of the Na-O 2 batteries.« less

  19. Thin and sexy vs. muscular and dominant: Prevalence of gendered body ideals in popular dolls and action figures.

    PubMed

    Boyd, Hope; Murnen, Sarah K

    2017-06-01

    We examined the extent to which popular dolls and action figures were portrayed with gendered body proportions, and the extent to which these gendered ideals were associated with heterosexual "success." We coded internet depictions of 72 popular female dolls and 71 popular male action figures from the websites of three national stores in the United States. Sixty-two percent of dolls had a noticeably thin body, while 42.3% of action figures had noticeably muscular bodies. Further, more thin dolls were portrayed with more sex object features than less thin dolls, including revealing, tight clothing and high-heeled shoes; bodies positioned with a curved spine, bent knee, and head cant; and with a sexually appealing facial expression. More muscular male action figures were more likely than less muscular ones to be shown with hands in fists and with an angry, emotional expression, suggesting male dominance. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Revealing the Reaction Mechanism of Na–O 2 Batteries using Environmental Transmission Electron Microscopy

    DOE PAGES

    Kwak, Won -Jin; Luo, Langli; Jung, Hun -Gi; ...

    2018-01-15

    Due to its high energy efficiency, sodium-oxygen (Na-O 2) batteries have been extensively studied recently. One of the critical challenges for the development of the Na-O 2 battery is the elucidation of the reaction mechanism, the reaction products, and thestructural and chemical evolution of reaction product as well as their correlation with the battery performance. Herein, in-situ TEM was employed to probe the reaction mechanism and the structural evolution of the discharge products in Na-O 2 batteries. The discharge product is featured by the formation of both cubic and conformal NaO 2. It has been noticed that the impingement ofmore » reaction product (NaO 2) can lead to the coarsening of the particle through coalescence. We also investigated the stability of the discharge product, noticing that the reaction product NaO 2 is stable in the case of solid electrolyte. Here, the present work provide unprecedented insight for the development of the Na-O 2 batteries.« less

  1. Temperature-responsive grafted polymer brushes obtained from renewable sources with potential application as substrates for tissue engineering

    NASA Astrophysics Data System (ADS)

    Raczkowska, Joanna; Stetsyshyn, Yurij; Awsiuk, Kamil; Lekka, Małgorzata; Marzec, Monika; Harhay, Khrystyna; Ohar, Halyna; Ostapiv, Dmytro; Sharan, Mykola; Yaremchuk, Iryna; Bodnar, Yulia; Budkowski, Andrzej

    2017-06-01

    The novel temperature-responsive poly(cholesteryl methacylate) (PChMa) coatings derived from renewable sources were synthesized and characterized. Temperature induced changes in wettability were accompanied by surface roughness modifications, traced with AFM. Topographies recorded for temperatures increasing from 5 to 25 °C showed a slight but noticeable increase of calculated root mean square (RMS) roughness by a factor of 1.5, suggesting a horizontal rearrangement in the structure of PChMa coatings. Another structural reordering was observed in the 55-85 °C temperature range. The recorded topography changed noticeably from smooth at 55 °C to very structured and rough at 60 °C and returned eventually to relatively smooth at 85 °C. In addition, temperature transitions of PChMa molecules were revealed by DSC measurements. The biocompatibility of the PChMa-grafted coatings was shown for cultures of granulosa cells and a non malignant bladder cancer cell (HCV29 line) culture.

  2. Dune Transition in the High Southern Latitudes

    NASA Image and Video Library

    2017-04-19

    Sand dune populations on Mars can vary widely with respect to morphology, relief, and activity. One of the most striking examples occurs with the many dune fields of the high Southern latitudes. When we venture south of -60 degrees latitude, we see increasing signs of dune degradation, with subdued dune brinks and broad sandy aprons, rather than sharp, dune crests and distinct boundaries. Dunes this far south are also very modest in height, often consisting solely of flat sand sheets. Additionally, global monitoring campaigns are revealing a noticeable lack of changes in these bedform positions, whereas many dunes and ripples to the north are migrating across the surface. This image shows a moderate sized dune field (-72 degrees latitude) that displays most of these morphologic features and a noticeable absence of dune crests. This transition is likely related to polar processes, ground ice, and changes in regional climate relative to the rest of the planet. https://photojournal.jpl.nasa.gov/catalog/PIA21595

  3. Fatigue Behavior of Inconel 718 TIG Welds

    NASA Astrophysics Data System (ADS)

    Alexopoulos, Nikolaos D.; Argyriou, Nikolaos; Stergiou, Vasillis; Kourkoulis, Stavros K.

    2014-08-01

    Mechanical behavior of reference and TIG-welded Inconel 718 specimens was examined in the present work. Tensile, constant amplitude fatigue, and fracture toughness tests were performed in ambient temperature for both, reference and welded specimens. Microstructure revealed the presence of coarse and fine-grained heat-affected zones. It has been shown that without any post-weld heat treatment, welded specimens maintained their tensile strength properties while their ductility decreased by more than 40%. It was found that the welded specimens had lower fatigue life and this decrease was a function of the applied fatigue maximum stress. A 30% fatigue life decrease was noticed in the high cycle fatigue regime for the welded specimens while this decrease exceeded 50% in the low cycle fatigue regime. Cyclic stress-strain curves showed that Inconel 718 experiences a short period of hardening followed by softening for all fatigue lives. Cyclic fatigue response of welded specimens' exhibited cyclically stable behavior. Finally, a marginal decrease was noticed in the Mode I fracture toughness of the welded specimens.

  4. Cystic Lymphangioma of the Chest Wall in a 5-Year-Old Male Patient: A Rare and Atypical Localization—A Case Report and Comprehensive Review of the Literature

    PubMed Central

    Kaselas, Christos; Kalogirou, Maria; Konstantinos, Farmakis; Feidantsis, Thomas; Eleni, Papacrivou

    2017-01-01

    Lymphangioma is a benign congenital malformation. The extremely rare and atypical localization of a lymphangioma in the chest wall was the real motive for the present case study. A 5-year-old boy was admitted to the Emergency Department of the 1st Department of Pediatric Surgery, Aristotle University of Thessaloniki, due to the presence of a mildly painful swelling in the left lateral chest wall, which was first noticed three months ago, after a blunt injury during sport. Physical examination revealed the presence of a palpable, spherical, painful, nut-sized subcutaneous lesion in the left lateral chest wall, respectively, with the anterior axillary line, at the height of the 6th to 7th intercostal space. Presence of ecchymosis on the overlying skin was also noticed. During palpation, we did not notice fluctuation, while transillumination was not feasible. Performance of ultrasonography, including Doppler color flow imaging, followed, depicting a subcutaneous cystic lesion, 2.1⁎3.2 cm in dimensions, without extension to the thoracic cavity. Scheduled surgical excision of the lesion was decided. Histopathological examination documented the diagnosis of cystic lymphangioma. Patient is still followed up on a 6-month basis. He remains asymptomatic, after 2 years, without indication of relapse. PMID:29201481

  5. Genistein in 1:1 Inclusion Complexes with Ramified Cyclodextrins: Theoretical, Physicochemical and Biological Evaluation

    PubMed Central

    Danciu, Corina; Soica, Codruta; Oltean, Mircea; Avram, Stefana; Borcan, Florin; Csanyi, Erzsebet; Ambrus, Rita; Zupko, Istvan; Muntean, Delia; Dehelean, Cristina A.; Craina, Marius; Popovici, Ramona A.

    2014-01-01

    Genistein is one of the most studied phytocompound in the class of isoflavones, presenting a notable estrogenic activity and in vitro and/or in vivo benefits in different types of cancer such as those of the bladder, kidney, lung, pancreatic, skin and endometrial cancer. A big inconvenience for drug development is low water solubility, which can be solved by using hydrophilic cyclodextrins. The aim of this study is to theoretically analyze, based on the interaction energy, the possibility of a complex formation between genistein (Gen) and three different ramified cyclodextrins (CD), using a 1:1 molar ratio Gen:CD. Theoretical data were correlated with a screening of both in vitro and in vivo activity. Proliferation of different human cancer cell lines, antimicrobial activity and angiogenesis behavior was analyzed in order to see if complexation has a beneficial effect for any of the above mentioned activities and if so, which of the three CDs is the most suitable for the incorporation of genistein, and which may lead to future improved pharmaceutical formulations. Results showed antiproliferative activity with different IC50 values for all tested cell lines, remarkable antimicrobial activity on Bacillus subtilis and antiangiogenic activity as revealed by CAM assay. Differences regarding the intensity of the activity for pure and the three Gen complexes were noticed as explained in the text. The data represent a proof that the three CDs can be used for furtherer research towards practical use in the pharmaceutical and medical field. PMID:24473144

  6. Microbial community structure and density under different tree species in an acid forest soil (Morvan, France).

    PubMed

    Lejon, David P H; Chaussod, Rémi; Ranger, Jacques; Ranjard, Lionel

    2005-11-01

    Overexploitation of forests to increase wood production has led to the replacement of native forest by large areas of monospecific tree plantations. In the present study, the effects of different monospecific tree cover plantations on density and composition of the indigenous soil microbial community are described. The experimental site of "Breuil-Chenue" in the Morvan (France) was the site of a comparison of a similar mineral soil under Norway spruce (Picea abies), Douglas fir (Pseudotuga menziesii), oak (Quercus sessiflora), and native forest [mixed stand dominated by oak and beech (Fagus sylvatica)]. Sampling was performed during winter (February) at three depths (0-5, 5-10, and 10-15 cm). Abundance of microorganisms was estimated via microbial biomass measurements, using the fumigation-extraction method. The genetic structure of microbial communities was investigated using the bacterial- and fungal-automated ribosomal intergenic spacer analysis (B-ARISA and F-ARISA, respectively) DNA fingerprint. Only small differences in microbial biomass were observed between tree species, the highest values being recorded under oak forest and the lowest under Douglas fir. B- and F-ARISA community profiles of the different tree covers clustered separately, but noticeable similarities were observed for soils under Douglas fir and oak. A significant stratification was revealed under each tree species by a decrease in microbial biomass with increasing depths and by distinct microbial communities for each soil layer. Differences in density and community composition according to tree species and depth were related to soil physicochemical characteristics and organic matter composition.

  7. Hodgkin Lymphoma revealed by epidural spinal cord compression.

    PubMed

    Ghedira, Khalil; Matar, Nidhal; Bouali, Sofiene; Zehani, Alia; Boubaker, Adnen; Jemel, Hafedh

    2018-01-30

    Hodgkin Lymphoma is rarely diagnosed as spinal cord compression syndrome. Caused by an epidural mass, this complication is often encountered in a late stage of the disease. We report the case of a 40-year-old man presenting with symptoms of low thoracic spinal cord compression due to an epidural tumor on the MRI. Emergent surgery was undertaken on this patient, consisting in laminectomy and tumor resection. After surgery, pain relief and mild neurological improvement were noticed. The histological study revealed a Hodgkin Lymphoma and the patient was referred to chemotherapy and radiotherapy. Though chemotherapy is the gold standard treatment for Hodgkin Lymphoma, surgical spinal decompression may be required in epidural involvement of the disease. Diagnosis may be suspected in the presence of lymphadenopathy and general health decay.

  8. Role of Silver Salts Lattice Energy on Conductivity Drops in Chitosan Based Solid Electrolyte: Structural, Morphological and Electrical Characteristics

    NASA Astrophysics Data System (ADS)

    Aziz, Shujahadeen B.; Abdullah, Omed Gh.; Hussein, Sarkawt A.

    2018-03-01

    The influence of anion type on silver ion reduction and drop in direct current (DC) conductivity was investigated experimentally. The structural, optical, morphological and electrical properties of the samples were investigated using x-ray diffraction (XRD), ultraviolet-visible (UV-Vis), optical micrographs (OM) and impedance spectroscopy. The XRD results reveal significant disruption in the crystalline structure of chitosan (CS) for different concentrations of silver nitrate (AgNt) salt. The localized surface resonance plasmonic (LSRP) peaks that were observed for CS:AgNt samples, along with the white silver specs detected by OM technique confirm the formation of Ag nanoparticles. The appearance of obvious dark regions in the CS:AgNt system reveals the existence of a large percentage of amorphous domains. The nonexistence of spherulitic texture confirms the amorphous nature of the samples. The second semicircle in an impedance plot can be attributed to an Ag nanoparticle grain boundary. The established relationships between dielectric constant and carrier concentration and the behavior of dielectric constant versus salt concentration were used to explain the phenomenon of ion-ion association. The continuous increase of DC conductivity was noticed at high temperatures, which was then explained on the basis of lattice energy of silver salts. The influences of anion size on the rate of silver ion reductions are also interpreted.

  9. ON THE STAR FORMATION PROPERTIES OF VOID GALAXIES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moorman, Crystal M.; Moreno, Jackeline; White, Amanda

    2016-11-10

    We measure the star formation properties of two large samples of galaxies from the SDSS in large-scale cosmic voids on timescales of 10 and 100 Myr, using H α emission line strengths and GALEX FUV fluxes, respectively. The first sample consists of 109,818 optically selected galaxies. We find that void galaxies in this sample have higher specific star formation rates (SSFRs; star formation rates per unit stellar mass) than similar stellar mass galaxies in denser regions. The second sample is a subset of the optically selected sample containing 8070 galaxies with reliable H i detections from ALFALFA. For the fullmore » H i detected sample, SSFRs do not vary systematically with large-scale environment. However, investigating only the H i detected dwarf galaxies reveals a trend toward higher SSFRs in voids. Furthermore, we estimate the star formation rate per unit H i mass (known as the star formation efficiency; SFE) of a galaxy, as a function of environment. For the overall H i detected population, we notice no environmental dependence. Limiting the sample to dwarf galaxies still does not reveal a statistically significant difference between SFEs in voids versus walls. These results suggest that void environments, on average, provide a nurturing environment for dwarf galaxy evolution allowing for higher specific star formation rates while forming stars with similar efficiencies to those in walls.« less

  10. Extracorporeal shockwave lithotripsy: urine cytology findings.

    PubMed

    Kumar, P V; Salami, K; Tadayyon, A R

    2008-12-01

    To describe the urine cytology findings before and after stone therapy with extracorporeal shock wave lithotripsy (ESWL) and discuss its importance. The study consisted of 100 patients with a urinary tract stone (79 renal pelvic stones and 21 upper ureteric stones), 74 were male and 26 were female. The ages ranged 30-55 years. The average duration of symptoms was 3-8 years. The size of the stones varied from case to case ranging from 10.2 to 40 mm. Urine samples were obtained on three consecutive days before and after lithotripsy. The smears were stained by the Papanicolaou method. The smears before lithotripsy revealed a few red blood cells, inflammatory cells, epithelial cells and crystals (calcium oxalate, uric acid and triple phosphate). Atypical malignant looking cells and epithelial cell clusters were not noticed. After lithotripsy, the urine samples were examined at different periods, 24 hours, 2 weeks, 1 month, 2 months and 3 months. The smears revealed papillary clusters in all 100 patients within 24 hours and were always associated with inflammation. Atypical malignant looking cells appeared later, within 1-2 months in 21 patients, and were associated with inflammation (19 patients), RBC, crystals and papillary clusters. Most of the papillary clusters and atypical malignant looking cells disappeared before 3 months. The epithelial cell clusters and atypical cells were seen in urine smears after ESWL. Without knowing the previous history these findings can be confused with urothelial neoplasms.

  11. Experimental investigation on flexure and impact properties of injection molded polypropylene-nylon 6-glass fiber polymer composites

    NASA Astrophysics Data System (ADS)

    Nuruzzaman, D. M.; Kusaseh, N. M.; Chowdhury, M. A.; Rahman, N. A. N. A.; Oumer, A. N.; Fatchurrohman, N.; Iqbal, A. K. M. A.; Ismail, N. M.

    2018-04-01

    In this research study, glass fiber (GF) reinforced polypropylene (PP)-nylon 6 (PA6) polymer blend composites were prepared using injection molding process. Specimens of four different compositions such as 80%PP+20%PA6, 80%PP+18%PA6+2%GF, 80%PP+16%PA6+4%GF and 80%PP+14%PA6+6%GF were prepared. In the injection molding process, suitable process parameters were selected depending on the type of composite specimen in producing defects free dog bone shaped specimens. Flexure and impact tests were carried out according to ASTM standard. The important flexure properties such as flexural modulus, flexural yield strength, flexural strength and flexural strain were investigated. The obtained results revealed that flexural modulus of 80%PP+20%PA6 polymer blend is the lowest and the polymer blend composite shows steadily improved modulus as the glass fiber content is increased. Results also showed that flexural strength of pure polymer blend is the lowest but it improves gradually when the glass fiber content is increased. Impact test results revealed that impact strength of 80%PP+20%PA6 polymer blend is the highest whereas all the composites show reduced impact strength or toughness. It is noticed that 80%PP+14%PA6+6%GF composite exhibits the lowest impact strength.

  12. Visual just noticeable differences

    NASA Astrophysics Data System (ADS)

    Nankivil, Derek; Chen, Minghan; Wooley, C. Benjamin

    2018-02-01

    A visual just noticeable difference (VJND) is the amount of change in either an image (e.g. a photographic print) or in vision (e.g. due to a change in refractive power of a vision correction device or visually coupled optical system) that is just noticeable when compared with the prior state. Numerous theoretical and clinical studies have been performed to determine the amount of change in various visual inputs (power, spherical aberration, astigmatism, etc.) that result in a just noticeable visual change. Each of these approaches, in defining a VJND, relies on the comparison of two visual stimuli. The first stimulus is the nominal or baseline state and the second is the perturbed state that results in a VJND. Using this commonality, we converted each result to the change in the area of the modulation transfer function (AMTF) to provide a more fundamental understanding of what results in a VJND. We performed an analysis of the wavefront criteria from basic optics, the image quality metrics, and clinical studies testing various visual inputs, showing that fractional changes in AMTF resulting in one VJND range from 0.025 to 0.075. In addition, cycloplegia appears to desensitize the human visual system so that a much larger change in the retinal image is required to give a VJND. This finding may be of great import for clinical vision tests. Finally, we present applications of the VJND model for the determination of threshold ocular aberrations and manufacturing tolerances of visually coupled optical systems.

  13. Studying the urban thermal environment under a human-biometeorological point of view: The case of a large coastal metropolitan city, Athens

    NASA Astrophysics Data System (ADS)

    Katavoutas, George; Georgiou, Giorgos K.; Asimakopoulos, Dimosthenis N.

    2015-01-01

    The thermal environment in modern cities has become potentially unfavorable and harmful for its residents, as a result of urbanization and industrialization. Exposure to these extreme thermal conditions increases the heat stress of people in cities considerably. In this context, the present study aims to investigate the urban thermal environment of the large coastal metropolitan city of Athens, in a human-biometeorologically significant way, utilizing the thermo-physiological assessment index PET. The analysis was based on three hour measurements derived from three-year datasets (2006-2009), at 12 monitoring sites located in the urban complex of Athens, on its boundaries and beyond them. The differences of PET values have been investigated in order to attribute urban and exurban thermal characteristics to the considered sites. The frequency and spatial distribution of PET as well as the urban/rural differences of PET have also been analyzed. Finally, a trend analysis has been applied in order to detect possible PET trends by employing long-term recording data (1985-2008). In terms of thermal human-biometeorological conditions, the analysis reveals that among the considered stations, those located inside the urban complex and the industrialized area present urban thermal characteristics, regardless the fact that they are installed either in a park and on a hill or at an open field. The spatial distribution of PET, at 0200 LST, shows a difference of about 3 to 4 °C, on the main axis of the city (SSW-NNE) in the summer period, while the difference exceeds 2.5 °C in the winter period. In general, cooler (less warm) thermal perception is observed at the north/northeast sites of the city as well as at the areas beyond the eastern boundaries of it. The PET differences between urban and rural sites hold a positive sign, except of those at 0500 LST and at 0800 LST. The highest differences are noted at 1400 LST and the most intense of them is noticed in the summer period (exceeds 5 °C). The trend analysis reveals statistically significant increasing heat stress for certain stations and months.

  14. Clinical research on erythrocyte deformability with different doses of He-Ne exposure in patient with ischemia disease

    NASA Astrophysics Data System (ADS)

    Zhao, Yanping; Liu, Song-hao; Sun, Jinbo; Luo, Gangyue; Hua, Rong; Liu, Qianqin

    2005-01-01

    The aim of this study was to test human erythrocyte deformability with the exposure of erythrocyte from apoplexy patient and other ischemia diseases, contracted with normal donors' blood sample, and the doses-effect of Low-power He_Ne laser in vitro were discussed. Fresh blood sample from adult health donors and patients with different diseases such as apoplexy, diabetes, heart block etc in emergency department were collected and divided into different groups in which there were no less than 6 persons. Fresh human blood samples were irradiated with a He-Ne laser (Lamba=632.8nm), power output around 4.5MW, 9MW, 15mW, and 18mW, et al., exposure time from 7.5min, 15min, and 30min, operating in continuous wave. Measurements of human erythrocyte deformability were taken. Erythrocyte deformability appearance shown some different in the health contracted group and the other ischemia disease group. Some notice difference also shown among some disease group with nonirradiation and the same disease group with laser irradiation. The dose-effects of He-Ne laser therapy was discussed on the further research on the erythrocyte deformability of blood sample from patients with apoplexy disease treated with He-Ne laser at different doses, and a certain optimal doses which could take a beneficial effect in clinic were speculated on. This study revealed that the He-Ne laser have some different effects on erythrocyte deformability in vitro, which were related with the disease condition, red cell state, and outpower-doses, et al closely.

  15. [Case report of melanoma-associated retinopathy associated with positive auto-antibodies against retinal bipolar cells].

    PubMed

    Hanaya, Junko; Nakamura, Yasuko; Nejima, Ryouhei; Miyata, Kazunori; Mera, Kentarou; Ohguro, Hiroshi; Yamamoto, Shuichi

    2011-06-01

    We report a case of melanoma-associated retinopathy (MAR) associated with positive auto-antibodies against retinal bipolar cells, which has been rarely reported in Japan. A 33 year-old woman noticed shimmering vision, photopsias, blurred vision, and night blindness OS in April 2009, and visited Kagoshima Miyata Eye Clinic in May 2009. She had been continuously treated for malignant melanoma on her left finger since 2007. At her initial visit, the corrected visual acuity was 1.5 OD and 1.2 OS, and slit-lamp examination revealed clear ocular media OU. Funduscopic examination showed normal appearance of the retina OU, except for a mild narrowing of the retinal arteries OS. Humphrey field analyzer revealed a reduction of retinal sensitivity within the central 30 degrees OS. The maximum left eye response of electroretinogram (ERG) showed a negative waveform. The immuno-cytochemical test revealed antibodies against retinal bipolar cells, which confirmed the diagnosis of MAR. Characteristic subjective symptoms, Humphrey field analyzer and ERG are useful for the diagnosis of MAR.

  16. Uremic Conditions Drive Human Monocytes to Pro-Atherogenic Differentiation via an Angiotensin-Dependent Mechanism

    PubMed Central

    Trojanowicz, Bogusz; Ulrich, Christof; Seibert, Eric; Fiedler, Roman; Girndt, Matthias

    2014-01-01

    Aims Elevated expression levels of monocytic-ACE have been found in haemodialysis patients. They are not only epidemiologically linked with increased mortality and cardiovascular disease, but may also directly participate in the initial steps of atherosclerosis. To further address this question we tested the role of monocytic-ACE in promotion of atherosclerotic events in vitro under conditions mimicking those of chronic renal failure. Methods and Results Treatment of human primary monocytes or THP-1 cells with uremic serum as well as PMA-induced differentiation led to significantly up-regulated expression of ACE, further increased by additional treatment with LPS. Functionally, these monocytes revealed significantly increased adhesion and transmigration through endothelial monolayers. Overexpression of ACE in transfected monocytes or THP-1 cells led to development of more differentiated, macrophage-like phenotype with up-regulated expression of Arg1, MCSF, MCP-1 and CCR2. Expression of pro-inflammatory cytokines TNFa and IL-6 were also noticeably up-regulated. ACE overexpression resulted in significantly increased adhesion and transmigration properties. Transcriptional screening of ACE-overexpressing monocytes revealed noticeably increased expression of Angiotensin II receptors and adhesion- as well as atherosclerosis-related ICAM-1 and VCAM1. Inhibition of monocyte ACE or AngII-receptor signalling led to decreased adhesion potential of ACE-overexpressing cells. Conclusions Taken together, these data demonstrate that uremia induced expression of monocytic-ACE mediates the development of highly pro-atherogenic cells via an AngII-dependent mechanism. PMID:25003524

  17. 77 FR 54636 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ...)(A)(xxxii) to mean a ``long'' and ``short'' position in different call option series, different put...)(xxxii) (renumbered as 4210(f)(2)(A)(xxvii)) that defines an OTC option as an over-the-counter option...

  18. Reproduction of Difference through Learning about a "Different Culture": The Paradox of Double Subject Positions and the Pedagogy of the Privileged

    ERIC Educational Resources Information Center

    Doerr, Neriko Musha

    2015-01-01

    Culture is not a predetermined, static, bounded unit. Both its boundaries and what is considered cultural difference are constructed through social processes. Ray McDermott and Herve Varenne (1995) argue that only certain differences are noticed, usually according to what is regarded as meaningful difference in one's own society. For example, in a…

  19. The Effect of Graft Strength on Knee Laxity and Graft In-Situ Forces after Posterior Cruciate Ligament Reconstruction

    PubMed Central

    Lai, Yu-Shu; Chen, Wen-Chuan; Huang, Chang-Hung; Cheng, Cheng-Kung; Chan, Kam-Kong; Chang, Ting-Kuo

    2015-01-01

    Surgical reconstruction is generally recommended for posterior cruciate ligament (PCL) injuries; however, the use of grafts is still a controversial problem. In this study, a three-dimensional finite element model of the human tibiofemoral joint with articular cartilage layers, menisci, and four main ligaments was constructed to investigate the effects of graft strengths on knee kinematics and in-situ forces of PCL grafts. Nine different graft strengths with stiffness ranging from 0% (PCL rupture) to 200%, in increments of 25%, of an intact PCL’s strength were used to simulate the PCL reconstruction. A 100 N posterior tibial drawer load was applied to the knee joint at full extension. Results revealed that the maximum posterior translation of the PCL rupture model (0% stiffness) was 6.77 mm in the medial compartment, which resulted in tibial internal rotation of about 3.01°. After PCL reconstruction with any graft strength, the laxity of the medial tibial compartment was noticeably improved. Tibial translation and rotation were similar to the intact knee after PCL reconstruction with graft strengths ranging from 75% to 125% of an intact PCL. When the graft’s strength surpassed 150%, the medial tibia moved forward and external tibial rotation greatly increased. The in-situ forces generated in the PCL grafts ranged from 13.15 N to 75.82 N, depending on the stiffness. In conclusion, the strength of PCL grafts have has a noticeable effect on anterior-posterior translation of the medial tibial compartment and its in-situ force. Similar kinematic response may happen in the models when the PCL graft’s strength lies between 75% and 125% of an intact PCL. PMID:26001045

  20. The effect of graft strength on knee laxity and graft in-situ forces after posterior cruciate ligament reconstruction.

    PubMed

    Lai, Yu-Shu; Chen, Wen-Chuan; Huang, Chang-Hung; Cheng, Cheng-Kung; Chan, Kam-Kong; Chang, Ting-Kuo

    2015-01-01

    Surgical reconstruction is generally recommended for posterior cruciate ligament (PCL) injuries; however, the use of grafts is still a controversial problem. In this study, a three-dimensional finite element model of the human tibiofemoral joint with articular cartilage layers, menisci, and four main ligaments was constructed to investigate the effects of graft strengths on knee kinematics and in-situ forces of PCL grafts. Nine different graft strengths with stiffness ranging from 0% (PCL rupture) to 200%, in increments of 25%, of an intact PCL's strength were used to simulate the PCL reconstruction. A 100 N posterior tibial drawer load was applied to the knee joint at full extension. Results revealed that the maximum posterior translation of the PCL rupture model (0% stiffness) was 6.77 mm in the medial compartment, which resulted in tibial internal rotation of about 3.01°. After PCL reconstruction with any graft strength, the laxity of the medial tibial compartment was noticeably improved. Tibial translation and rotation were similar to the intact knee after PCL reconstruction with graft strengths ranging from 75% to 125% of an intact PCL. When the graft's strength surpassed 150%, the medial tibia moved forward and external tibial rotation greatly increased. The in-situ forces generated in the PCL grafts ranged from 13.15 N to 75.82 N, depending on the stiffness. In conclusion, the strength of PCL grafts have has a noticeable effect on anterior-posterior translation of the medial tibial compartment and its in-situ force. Similar kinematic response may happen in the models when the PCL graft's strength lies between 75% and 125% of an intact PCL.

  1. Lumbar diskectomy in a human-habituated mountain gorilla (Gorilla beringei beringei).

    PubMed

    Aryan, Henry E; Jandial, Rahul; Nakaji, Peter; Greenberg, Mark S; Janssen, Don L; Huang, Johnson; Taylor, William R

    2006-02-01

    The authors report a case of a human-habituated mountain gorilla, Alvila, resident at the San Diego Zoo, who was found to have a herniated intervertebral lumbar disc after being attacked by the gorilla troop's silverback male gorilla. Ultimately, the gorilla required surgical intervention for her disease and made a full recovery. To our knowledge, this is the only known case of spine surgery. A 36-year-old female human-habituated mountain gorilla (Gorilla beringei beringei), resident at the San Diego Zoo, was noticed by caregivers to walk with a substantial limp after being attacked by the gorilla troop's silverback male gorilla. Magnetic resonance (MR) imaging of her lumbar spine revealed a large herniated disk at the L1-2 level on the right. This finding appeared to correlate well with the gorilla's symptoms. The gorilla underwent a lumbar diskectomy under loupe. Post-operatively the gorilla did very well. The right leg weakness was immediately improved post-operatively. The gorilla continued to "crutch walk" initially, swinging on the upper extremities and not bearing weight on the lowers. However, by 2 weeks the limp was no longer noticeable to the zoo caregivers. The wound healed well and there was no evidence of wound infection or CSF leak. The gorilla was reunited with her troop and has reintegrated well socially. With 10 months of follow-up, the gorilla continues to do well. This is the only known case of spine surgery in a gorilla. For best surgical results, one needs to consider the similarities and differences between the gorilla and human vertebral anatomy. We believe that careful pre-operative planning contributed to the good early post-operative result. Ultimate assessment of the long-term outcome will require additional follow-up.

  2. Biocompatibility of bio based calcium carbonate nanocrystals aragonite polymorph on NIH 3T3 fibroblast cell line.

    PubMed

    Kamba, Abdullahi Shafiu; Ismail, Maznah; Ibrahim, Tengku Azmi Tengku; Zakaria, Zuki Abu Bakar

    2014-01-01

    Currently, there has been extensive research interest for inorganic nanocrystals such as calcium phosphate, iron oxide, silicone, carbon nanotube and layered double hydroxide as a drug delivery system especially in cancer therapy. However, toxicological screening of such particles is paramount importance before use as delivery carrier. In this study we examine the biocompatibility of CaCO3 nanocrystal on NIH 3T3 cell line. Transmission and field emission scanning electron microscopy (TEM and FESEM) were used for the characterisation of CaCO3 nanocrystals. Cytotoxicity and genotoxic effect of calcium carbonate nanocrystals in cultured mouse embryonic fibroblast NIH 3T3 cell line using various bioassays including MTT, and Neutral red/Trypan blue double-staining assays. LDH, BrdU and reactive oxygen species were used for toxicity analysis. Cellular morphology was examined by scanning electron microscopy (SEM) and confocal fluorescence microscope. The outcome of the analyses revealed a clear rod-shaped aragonite polymorph of calcium carbonate nanocrystal. The analysed cytotoxic and genotoxicity of CaCO3 nanocrystal on NIH 3T3 cells using different bioassays revealed no significance differences as compared to control. A slight decrease in cell viability was noticed when the cells were exposed to higher concentrations of 200 to 400 µg/ml, while increase in ROS generation and LDH released at 200 and 400 µg/ml was observed. The study has shown that CaCO3 nanocrystal is biocompatible and non toxic to NIH 3T3 fibroblast cells. The analysed results offer a promising potential of CaCO3 nanocrystal for the development of intracellular drugs, genes and other macromolecule delivery systems.

  3. Chiral Graphene Quantum Dots

    DOE PAGES

    Suzuki, Nozomu; Wang, Yichun; Elvati, Paolo; ...

    2016-01-15

    Chiral nanostructures from metals and semiconductors attract wide interest as components for polarization-enabled optoelectronic devices. Similarly to other fields of nanotechnology, graphene-based materials can greatly enrich physical and chemical phenomena associated with optical and electronic properties of chiral nanostructures and facilitate their applications in biology as well as other areas. Here, we report that covalent attachment of l/d-cysteine moieties to the edges of graphene quantum dots (GQDs) leads to their helical buckling due to chiral interactions at the “crowded” edges. Circular dichroism (CD) spectra of the GQDs revealed bands at ca. 210–220 and 250–265 nm that changed their signs formore » different chirality of the cysteine edge ligands. The high-energy chiroptical peaks at 210–220 nm correspond to the hybridized molecular orbitals involving the chiral center of amino acids and atoms of graphene edges. Diverse experimental and modeling data, including density functional theory calculations of CD spectra with probabilistic distribution of GQD isomers, indicate that the band at 250–265 nm originates from the three-dimensional twisting of the graphene sheet and can be attributed to the chiral excitonic transitions. The positive and negative low-energy CD bands correspond to the left and right helicity of GQDs, respectively. Exposure of liver HepG2 cells to l/d-GQDs reveals their general biocompatibility and a noticeable difference in the toxicity of the stereoisomers. Molecular dynamics simulations demonstrated that d-GQDs have a stronger tendency to accumulate within the cellular membrane than l-GQDs. Finally, emergence of nanoscale chirality in GQDs decorated with biomolecules is expected to be a general stereochemical phenomenon for flexible sheets of nanomaterials.« less

  4. Cognitive, emotional and social phenotyping of mice in an observer-independent setting.

    PubMed

    Dere, Ekrem; Ronnenberg, Anja; Tampe, Björn; Arinrad, Sahab; Schmidt, Manuela; Zeisberg, Elisabeth; Ehrenreich, Hannelore

    2018-04-01

    Based on the intellicage paradigm, we have developed a novel cognitive, emotional and social phenotyping battery that permits comprehensive standardized behavioral characterization of mice in an experimenter-independent social setting. Evaluation of this battery in a large number of male and female C57BL/6 wildtype mice, tested in >20 independent cohorts, revealed high reproducibility of the behavioral readouts and may serve as future reference tool. We noticed robust sex-specific differences in general activity, cognitive and emotional behavior, but not regarding preference for social pheromones. Specifically, female mice revealed higher activity, decreased sucrose preference, impaired reversal and place-time-reward learning. Furthermore, female mice reacted more sensitively than males to reward-withdrawal showing a negative emotional contrast/Crespi-effect. In a series of validation experiments, we tested mice with different pathologies, including neuroligin-3 deficient mice (male Nlgn3 y/- and female Nlgn3 +/- ) for autistic behavior, oligodendrocyte-specific erythropoietin receptor knockout (oEpoR -/- ) mice for cognitive impairment, as well as mouse models of renal failure (unilateral ureteral obstruction and 5/6 nephrectomy) and of type 2 diabetes (ApoE -/- ) - for delineating potentially confounding effects of motivational factors (thirst, glucose-craving) on learning and memory assessments. As prominent features, we saw in Nlgn3 mutants reduced preference for social pheromones, whereas oEpoR -/- mice showed learning deficits in place or reversal learning tasks. Renal failure led to increased water intake, and diabetic metabolism to enhanced glucose preference, limiting interpretation of hereon based learning and memory performance in these mice. The phenotyping battery presented here may be well-suited as high-throughput multifaceted diagnostic instrument for translational neuropsychiatry and behavioral genetics. Copyright © 2018. Published by Elsevier Inc.

  5. Prostate anatomy in motheaten viable (me(v)) mice with mutations in the protein tyrosine phosphatase SHP-1.

    PubMed

    García-Tello, A; Angulo, J C; Rodriguez-Ubreva, J; Andrés, G; López, J I; Sánchez-Chapado, M; López-Ruiz, P; Colás, B

    2014-09-01

    To study prostate and seminal vesicle anatomy in viable motheaten (mev) with mutations in PTPN6 gene leading to a severe reduction in the activity of protein tyrosine phosphatase SHP-1. Homozygous mev mice exhibit multiple anomalies that include immunodeficiencies, increased proliferation of macrophage, neutrophil, and erythrocyte progenitors, decreased bone density and sterility. We analyzed macro- and microscopic anatomy of the seminal vesicle and prostate macro- and microscopic anatomy of 5 mev/mev and 8 wt/wt adult 7 week old mice. Computerized morphometric analysis was performed to measure the relative changes appearing in the epithelial volume of the different prostatic lobes. All mice studied revealed normal genital organs (penis, testis, epididymis, vas deferens) and bladder. The seminal vesicle was absent in all mev/mev individuals analyzed, being normal and very noticeable in wt/wt mice. The different glands that compose the prostatic complex (anterior, ventral and dorso-lateral prostate) were atrophied in mev/mev mice: anterior prostate 0.4 times, ventral 0.19 times, dorsal 0.35 times and lateral 0.28 times those of the respective regions in wt/wt mice. Microscopically, mev/mev mice revealed scarce and large prostatic ducts, acini severely atrophic with empty lumen and scarce loose epithelial component forming tufts and infoldings, and hyperplastic changes in fibromuscular stroma. The prostate of mev/mev mice exhibits signs of aberrant differentiation and the resulting phenotype may be related to the loss of function of SHP-1. Prostatic anomalies in these mice affect, together with defects in sperm maduration, for their sterility. These data suggest SHP-1 plays an important role in prostate epithelial morphogenesis. Copyright © 2014 AEU. Published by Elsevier Espana. All rights reserved.

  6. Contrasting aerosol optical and radiative properties between dust and urban haze episodes in megacities of Pakistan

    NASA Astrophysics Data System (ADS)

    Iftikhar, Muhammad; Alam, Khan; Sorooshian, Armin; Syed, Waqar Adil; Bibi, Samina; Bibi, Humera

    2018-01-01

    Satellite and ground based remote sensors provide vital information about aerosol optical and radiative properties. Analysis of aerosol optical and radiative properties during heavy aerosol loading events in Pakistan are limited and, therefore, require in-depth examination. This work examines aerosol properties and radiative forcing during Dust Episodes (DE) and Haze Episodes (HE) between 2010 and 2014 over mega cities of Pakistan (Karachi and Lahore). Episodes having the daily averaged values of Aerosol Optical Depth (AOD) exceeding 1 were selected. DE were associated with high AOD and low Ångström Exponent (AE) over Karachi and Lahore while high AOD and high AE values were associated with HE over Lahore. Aerosol volume size distributions (AVSD) exhibited a bimodal lognormal distribution with a noticeable coarse mode peak at a radius of 2.24 μm during DE, whereas a fine mode peak was prominent at a radius 0.25 μm during HE. The results reveal distinct differences between HE and DE for spectral profiles of several parameters including Single Scattering Albedo (SSA), ASYmmetry parameter (ASY), and the real and imaginary components of refractive index (RRI and IRI). The AOD-AE correlation revealed that dust was the dominant aerosol type during DE and that biomass burning and urban/industrial aerosol types were pronounced during HE. Aerosol radiative forcing (ARF) was estimated using the Santa Barbra DISORT Atmospheric Radiative Transfer (SBDART) model. Calculations revealed a negative ARF at the Top Of the Atmosphere (ARFTOA) and at the Bottom Of the Atmosphere (ARFBOA), with positive ARF within the Atmosphere (ARFATM) during both DE and HE over Karachi and Lahore. Furthermore, estimations of ARFATM by SBDART were shown to be in good agreement with values derived from AERONET data for DE and HE over Karachi and Lahore.

  7. Single cell qPCR reveals that additional HAND2 and microRNA-1 facilitate the early reprogramming progress of seven-factor-induced human myocytes

    PubMed Central

    Bektik, Emre; Dennis, Adrienne; Prasanna, Prateek; Madabhushi, Anant

    2017-01-01

    The direct reprogramming of cardiac fibroblasts into induced cardiomyocyte (CM)-like cells (iCMs) holds great promise in restoring heart function. We previously found that human fibroblasts could be reprogrammed toward CM-like cells by 7 reprogramming factors; however, iCM reprogramming in human fibroblasts is both more difficult and more time-intensive than that in mouse cells. In this study, we investigated if additional reprogramming factors could quantitatively and/or qualitatively improve 7-factor-mediated human iCM reprogramming by single-cell quantitative PCR. We first validated 46 pairs of TaqMan® primers/probes that had sufficient efficiency and sensitivity to detect the significant difference of gene expression between individual H9 human embryonic stem cell (ESC)-differentiated CMs (H9CMs) and human fibroblasts. The expression profile of these 46 genes revealed an improved reprogramming in 12-week iCMs compared to 4-week iCMs reprogrammed by 7 factors, indicating a prolonged stochastic phase during human iCM reprogramming. Although none of additional one reprogramming factor yielded a greater number of iCMs, our single-cell qPCR revealed that additional HAND2 or microRNA-1 could facilitate the silencing of fibroblast genes and yield a better degree of reprogramming in more reprogrammed iCMs. Noticeably, the more HAND2 expressed, the higher-level were cardiac genes activated in 7Fs+HAND2-reprogrammed iCMs. In conclusion, HAND2 and microRNA-1 could help 7 factors to facilitate the early progress of iCM-reprogramming from human fibroblasts. Our study provides valuable information to further optimize a method of direct iCM-reprogramming in human cells. PMID:28796841

  8. Single cell qPCR reveals that additional HAND2 and microRNA-1 facilitate the early reprogramming progress of seven-factor-induced human myocytes.

    PubMed

    Bektik, Emre; Dennis, Adrienne; Prasanna, Prateek; Madabhushi, Anant; Fu, Ji-Dong

    2017-01-01

    The direct reprogramming of cardiac fibroblasts into induced cardiomyocyte (CM)-like cells (iCMs) holds great promise in restoring heart function. We previously found that human fibroblasts could be reprogrammed toward CM-like cells by 7 reprogramming factors; however, iCM reprogramming in human fibroblasts is both more difficult and more time-intensive than that in mouse cells. In this study, we investigated if additional reprogramming factors could quantitatively and/or qualitatively improve 7-factor-mediated human iCM reprogramming by single-cell quantitative PCR. We first validated 46 pairs of TaqMan® primers/probes that had sufficient efficiency and sensitivity to detect the significant difference of gene expression between individual H9 human embryonic stem cell (ESC)-differentiated CMs (H9CMs) and human fibroblasts. The expression profile of these 46 genes revealed an improved reprogramming in 12-week iCMs compared to 4-week iCMs reprogrammed by 7 factors, indicating a prolonged stochastic phase during human iCM reprogramming. Although none of additional one reprogramming factor yielded a greater number of iCMs, our single-cell qPCR revealed that additional HAND2 or microRNA-1 could facilitate the silencing of fibroblast genes and yield a better degree of reprogramming in more reprogrammed iCMs. Noticeably, the more HAND2 expressed, the higher-level were cardiac genes activated in 7Fs+HAND2-reprogrammed iCMs. In conclusion, HAND2 and microRNA-1 could help 7 factors to facilitate the early progress of iCM-reprogramming from human fibroblasts. Our study provides valuable information to further optimize a method of direct iCM-reprogramming in human cells.

  9. Assessment of Climatological Trends of Sea Level over the Indian Coast Using Artificial Neural Network and Wavelet Techniques

    NASA Astrophysics Data System (ADS)

    Sudha Rani, N. N. V.; Satyanarayana, A. N. V.; Bhaskaran, Prasad Kumar

    2017-04-01

    In the present study, an attempt has been made to understand the variability of mean sea level (MSL) over east and west coast of India during 1973-2010. For this purpose, the monthly tide gauge data available over Kandla, Mumbai and Cochin along west coast and Diamond Harbour, Haldia, Visakhapatnam and Chennai along east coast obtained from PSMSL data archives has been considered. Sea level data from the tide gauge records show loss of data due to any disfunctioning of equipment or upgrade of the tide gauge resulting loss of data. It requires no gaps in the time series of MSL during the study period, and needs to be filled with better accuracy and hence artificial neural networks was implemented. To examine any periodicities of MSL variability, continuous wavelet analysis was conducted. The interrelationships between the stations in time-frequency space were examined, using cross and coherence wavelet analysis as well. The study reveals notable interannual variability of MSL. An observational analysis was done to understand the relation between inter-annual variability of MSL anomalies and ENSO. During positive (negative) SOI as associated with positive (negative) MSL anomaly was noticed significantly for the winter season over east (west) coast, where as during post-monsoon season this was observed for east coast and is less prevalent along the west coast. The observational analysis revealed that for the west (east) coast positive IOD showed significantly increased (decreased) MSL anomalies and negative IOD showed significantly decreased (increased) MSL anomalies. It is also found that the concurrent ENSO and IOD may have a different impact on MSL. The observations also reveal an increase of 1.353 mm/year on the east coast and observed a total 0.372 mm/year on the west coast.

  10. Human cowpox virus infection acquired from a circus elephant in Germany.

    PubMed

    Hemmer, Christoph J; Littmann, Martina; Löbermann, Micha; Meyer, Hermann; Petschaelis, Angelika; Reisinger, Emil C

    2010-09-01

    A 40-year-old Asian circus elephant developed mouth and trunk ulcers. Three weeks later, her 19-year-old animal warden noticed a vesicle on his forearm, evolving into a scab. Identical cowpox strains were isolated from lesions of the elephant and the warden. Cowpox virus could no longer be isolated after the scab disappeared, but PCR still revealed orthopox DNA. Healing was complete seven weeks later, leaving a 1 cm scar. Copyright © 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  11. Mechanical Reinforcement of Epoxy Composites with Carbon Fibers and HDPE

    NASA Astrophysics Data System (ADS)

    He, R.; Chang, Q.; Huang, X.; Li, J.

    2018-01-01

    Silanized carbon fibers (CFs) and a high-density polyethylene with amino terminal groups (HDPE) were introduced into epoxy resins to fabricate high-performance composites. A. mechanical characterization of the composites was performed to investigate the effect of CFs in cured epoxy/HDPE systems. The composites revealed a noticeable improvement in the tensile strength, elongation at break, flexural strength, and impact strength in comparison with those of neat epoxy and cured epoxy/HDPE systems. SEM micrographs showed that the toughening effect could be explained by yield deformations, phase separation, and microcracking.

  12. Alkaptonuria diagnosed in a 4-month-old baby girl: a case report

    PubMed Central

    Datta, Asok K; Mandal, Syamali; Dasgupta, Anindya; Ghosh, Tarun K

    2008-01-01

    The mother of a four month old female baby attended in the well baby clinic with the complaint of black staining of the diaper after few minutes of urination. The baby was born of a non consanguineous marriage, healthy and breast fed. Mother noticed that stain first at the age of two and half month. The urine when kept in a test tube for two hours turned black. Laboratory examination of urine revealed increased concentration of homogentisic acid. The patient was diagnosed as alkaptonuria. PMID:19014543

  13. Biological Differences and Social Equality: A Revolutionary Idea.

    ERIC Educational Resources Information Center

    Vaughter, Reesa M.

    Barriers to equitable scientific consideration of biological differences are being noticed by many scholars considering social equity. Many have observed the alliance and contamination of the biological and social sciences, reinforcing cultural biases. The uncritical acceptance and application of bio-medical models also produce inadequate methods…

  14. Combined impact of exercise and temperature in learning and memory performance of fluoride toxicated rats.

    PubMed

    Basha, P Mahaboob; Sujitha, N S

    2012-12-01

    In previous studies, we investigated a link between high fluoride exposure and functional IQ deficits in rats. This study is an extension conducted to explore the combined influence of physical exercise and temperature stress on the learning ability and memory in rats and to assess whether any positive modulation could be attenuated due to exercise regimen subjected to F-toxicated animals at different temperatures. Accumulation of ingested fluoride resulted significant inhibition in acetylcholinesterase activity (P < 0.05), plasma cortisol levels (P < 0.05), and impaired the acquisition, performance, latency time, and retention in fluoride-exposed animals. Fluoride-toxicated rats took more number of sessions during the learning phase [F (5, 35) = 19.065; P < 0.05] and post hoc analysis on the number of correct choices revealed that there was a significant effect of treatments [F (5, 30) = 15.763; P < 0.05]; sessions [F (8, 240) = 58.698; P < 0.05]; and also significant difference in the interactions [F (40, 240) = 1.583; P < 0.05]. The latency data also revealed a significant difference between groups [F (5, 30) = 28.085; P < 0.05]; time = [F (8, 240) = 136.314; P < 0.05]; and there was a significant difference in the interactions [F (40, 240) = 2.090; P < 0.05]. In order to ascertain if interdependence between fluoride concentrations and the foregoing free radical parameters, respective correlation coefficients were calculated and results clearly emphasize the positive role of exercise in the promotion of cognitive functions by decreasing fluoride levels in rat hippocampus. A significant recovery in cognitive function was noticed in all the exercised animals due to reduced burden of brain oxidative stress. In comparison to exercise regimens performed at different temperatures, high (35 °C) and low temperatures (20 °C) led to a slower acquisition and poor retention of the task when compared to thermo neutral temperatures (25 and 30 °C). Thus exercise up-regulate antioxidant defenses and promote learning abilities in fluorotic population.

  15. The Comparison of Visual Working Memory Representations with Perceptual Inputs

    ERIC Educational Resources Information Center

    Hyun, Joo-seok; Woodman, Geoffrey F.; Vogel, Edward K.; Hollingworth, Andrew; Luck, Steven J.

    2009-01-01

    The human visual system can notice differences between memories of previous visual inputs and perceptions of new visual inputs, but the comparison process that detects these differences has not been well characterized. In this study, the authors tested the hypothesis that differences between the memory of a stimulus array and the perception of a…

  16. 75 FR 18794 - Certain Orange Juice From Brazil: Preliminary Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ... made at different marketing stages (or their equivalent). See 19 CFR 351.412(c)(2). Substantial... a difference in the stages of marketing. Id. See also Notice of Final Determination of Sales at Less... at different stages in the marketing process than the U.S. sales, we reviewed the distribution system...

  17. 34 CFR 646.10 - How many applications may an eligible applicant submit and for what different populations may an...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... and for what different populations may an eligible application be submitted? 646.10 Section 646.10....10 How many applications may an eligible applicant submit and for what different populations may an... population. (b) For each grant competition, the Secretary designates, in the Federal Register notice inviting...

  18. 34 CFR 646.10 - How many applications may an eligible applicant submit and for what different populations may an...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... and for what different populations may an eligible application be submitted? 646.10 Section 646.10....10 How many applications may an eligible applicant submit and for what different populations may an... population. (b) For each grant competition, the Secretary designates, in the Federal Register notice inviting...

  19. 34 CFR 646.10 - How many applications may an eligible applicant submit and for what different populations may an...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... and for what different populations may an eligible application be submitted? 646.10 Section 646.10....10 How many applications may an eligible applicant submit and for what different populations may an... population. (b) For each grant competition, the Secretary designates, in the Federal Register notice inviting...

  20. 34 CFR 646.10 - How many applications may an eligible applicant submit and for what different populations may an...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... and for what different populations may an eligible application be submitted? 646.10 Section 646.10....10 How many applications may an eligible applicant submit and for what different populations may an... population. (b) For each grant competition, the Secretary designates, in the Federal Register notice inviting...

  1. Vive la Difference: What We Learn from Each Other by Teaching Together

    ERIC Educational Resources Information Center

    Rehling, Lu; Lindeman, Neil

    2010-01-01

    The authors are similar in sharing the academic discipline of professional writing and of both having had experience as writers and editors in the workplace, but they are different in many other and obvious ways. The students notice these differences, using, in course assessments, descriptive phrases to describe the contrast that include "yin and…

  2. Daily activity patterns of 2316 men and women from five countries differing in socioeconomic development.

    PubMed

    Sani, Mamane; Refinetti, Roberto; Jean-Louis, Girardin; Pandi-Perumal, S R; Durazo-Arvizu, Ramon A; Dugas, Lara R; Kafensztok, Ruth; Bovet, Pascal; Forrester, Terrence E; Lambert, Estelle V; Plange-Rhule, Jacob; Luke, Amy

    2015-06-01

    Daily rhythmicity in the locomotor activity of laboratory animals has been studied in great detail for many decades, but the daily pattern of locomotor activity has not received as much attention in humans. We collected waist-worn accelerometer data from more than 2000 individuals from five countries differing in socioeconomic development and conducted a detailed analysis of human locomotor activity. Body mass index (BMI) was computed from height and weight. Individual activity records lasting 7 days were subjected to cosinor analysis to determine the parameters of the daily activity rhythm: mesor (mean level), amplitude (half the range of excursion), acrophase (time of the peak) and robustness (rhythm strength). The activity records of all individual participants exhibited statistically significant 24-h rhythmicity, with activity increasing noticeably a few hours after sunrise and dropping off around the time of sunset, with a peak at 1:42 pm on average. The acrophase of the daily rhythm was comparable in men and women in each country but varied by as much as 3 h from country to country. Quantification of the socioeconomic stages of the five countries yielded suggestive evidence that more developed countries have more obese residents, who are less active, and who are active later in the day than residents from less developed countries. These results provide a detailed characterization of the daily activity pattern of individual human beings and reveal similarities and differences among people from five countries differing in socioeconomic development.

  3. Molecular characterization and evaluation of the emerging antibiotic-resistant Streptococcus pyogenes from eastern India.

    PubMed

    Ray, Dipanwita; Saha, Somnath; Sinha, Sukanta; Pal, Nishith Kumar; Bhattacharya, Basudev

    2016-12-12

    Group A Streptococcus strains causing wide variety of diseases, recently became noticeable in eastern India, are not amenable to standard treatment protocol thus enhancing the possibility of disease morbidity by becoming antibiotic resistance. The association of Lancefield group A Streptococcal variation with degree of vir architectural diversity was evaluated using emm typing and restriction fragment length polymorphism analyses. The antibiotic sensitivity patterns were examined by modified Kirby-Bauer method of disk diffusion. Percentage calculations, 95% confidence interval and one-way ANOVA were used to assess differences in proportions. Our observations revealed 20 different emm types and 13 different HaeIII vir typing patterns. A 1.2 kb fragment was found in all HaeIII typing pattern. Fragments of 1.2 kb and 550 bp were conserved in majority of the isolates. HinfI digestion was found proficient in differentiating the strains of same vir typing patterns. Strong predominance of speC (85%) and speF (80%) genes have been observed encoding exotoxins production. 4 isolates were found to be erythromycin resistant and were of genotype emm49. High degree of tetracycline resistance was shown by 53.57% isolates which belonged to 12 different emm genotypes. These findings suggested that in addition to emm typing, sequential application of HaeIII and HinfI restriction enzymes in vir typing analysis is an effective tool for group A streptococcal molecular characterization associated with antibiotic resistance.

  4. The co-movement of monetary policy and its time-varying nature: A DCCA approach

    NASA Astrophysics Data System (ADS)

    Rohit, Abhishek; Mitra, Subrata Kumar

    2018-02-01

    Employing a novel methodology of DCCA cross-correlation coefficient (ρDCCA), this study attempts to provide fresh evidences for the co-movement of monetary policies of the advanced (AEs) as well as the emerging economies (EMEs) vis-à-vis the United States. A higher degree of monetary co-movement as measured by ρDCCA values, is identified for the AEs as compared to the EMEs. Lower co-movement of monetary policy is especially noticeable in the short run for EMEs. We further investigate the time-varying nature of such co-movements for the AEs by splitting the period (1980-2014) into four sub periods and also by performing a rolling window estimation for the entire period to reveal smoother dynamics. Significant evidence of higher monetary coordination is revealed for sub-periods with stronger trade and financial linkages.

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Luo, Langli; Su, Mao; Yan, Pengfei

    The presence of water vapor, intentional or unavoidable, is crucial to many materials applications, such as steam generator, turbine engine, fuel cell, catalyst, and corrosion 1-6. Phenomenologically, water vapor has been noticed to accelerate oxidation of metals/alloys 7,8, however, the atomistic mechanisms remain elusive. Herein, through direct in situ atomic-scale transmission electron microscopy observation and density functional theory calculation, we reveal that water vapor enhanced oxidation of Ni-Cr alloy is associated with proton dissolution promoted vacancy formation, migration and clustering. Protons derived from water dissociation occupy interstitial position in the oxide lattice, which consequently leads to the lowering of bothmore » vacancy formation energy and the cation diffusion barrier. The atomic scale observations reveal a water vapor derived proton mediated oxide growth mechanism, which provides insights for reckoning many technological processes concerning materials in moist environment at elevated temperatures.« less

  6. [Tobacco advertising and promotions: changes in reported exposure in a cohort of Mexican smokers].

    PubMed

    Pérez-Hernández, Rosaura; Thrasher, James F; Rodríguez-Bolaños, Rosibel; Barrientos-Gutiérrez, Inti; Ibáñez-Hernández, Norma A

    2012-06-01

    To determine in a population-based sample of smokers the level exposure to tobacco industry marketing through different channels before and after their restriction through the General Tobacco Control Law of 2008. Data were analyzed from a cohort of adult smokers from four Mexican cities who were surveyed in 2007 and 2008. GEE models were estimated for each indicator of advertising and promotion exposure. Increases were found in report of receiving free samples of tobacco (3.7-8.1%), branded clothing (3.6-6.4%), noticing tobacco industry sponsored events (1.9-4.7%) and noticing ads in bars (21.4-28%). Noticing outdoor advertising decreased over this time (54.7 a 47.2%). Our findings confirm tobacco industry shifting of marketing efforts when advertising and promotion bans are not comprehensive. There is a need to monitor compliance with marketing bans while working to make them comprehensive.

  7. 16 CFR 680.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...'s opt-out rights. (4) Model notices. Model notices are provided in Appendix C of Part 698 of this...)(iii) of the Act and the Gramm-Leach-Bliley Act privacy notice. (c) Equivalent notices. A notice or...

  8. Proximal sensing of plant-pathogen interactions in spring barley with three fluorescence techniques.

    PubMed

    Leufen, Georg; Noga, Georg; Hunsche, Mauricio

    2014-06-24

    In the last years fluorescence spectroscopy has come to be viewed as an essential approach in key research fields of applied plant sciences. However, the quantity and particularly the quality of information produced by different equipment might vary considerably. In this study we investigate the potential of three optical devices for the proximal sensing of plant-pathogen interactions in four genotypes of spring barley. For this purpose, the fluorescence lifetime, the image-resolved multispectral fluorescence and selected indices of a portable multiparametric fluorescence device were recorded at 3, 6, and 9 days after inoculation (dai) from healthy leaves as well as from leaves inoculated with powdery mildew (Blumeria graminis) or leaf rust (Puccinia hordei). Genotype-specific responses to pathogen infections were revealed already at 3 dai by higher fluorescence mean lifetimes in the spectral range from 410 to 560 nm in the less susceptible varieties. Noticeable pathogen-induced modifications were also revealed by the 'Blue-to-Far-Red Fluorescence Ratio' and the 'Simple Fluorescence Ratio'. Particularly in the susceptible varieties the differences became more evident in the time-course of the experiment i.e., following the pathogen development. The relevance of the blue and green fluorescence to exploit the plant-pathogen interaction was demonstrated by the multispectral fluorescence imaging system. As shown, mildewed leaves were characterized by exceptionally high blue fluorescence, contrasting the values observed in rust inoculated leaves. Further, we confirm that the intensity of green fluorescence depends on the pathogen infection and the stage of disease development; this information might allow a differentiation of both diseases. Moreover, our results demonstrate that the detection area might influence the quality of the information, although it had a minor impact only in the current study. Finally, we highlight the relevance of different excitation-emission channels to better understand and evaluate plant-physiological alterations due to pathogen infections.

  9. [Factors related to awareness on tobacco advertisement and promotion among adults in six cities in China].

    PubMed

    Yang, Yan; Wu, Xi; Li, Qiang; Jiao, Shu-fang; Li, Xun; Li, Xin-jian; Zhu, Guo-ping; Du, Lin; Zhao, Jian-hua; Jiang, Yuan; Feng, Guo-ze

    2009-04-01

    To know the situation of tobacco advertisement, promotions and related factors in six cities in China. 4815 adults (above 18 years), selected form Beijing, Shanghai, Shenyang, Changsha, Guangzhou and Yinchuan through probability proportionate sampling and simple random sampling, were investigated through questionnaires. The most commonly reported channels that smokers noticed tobacco advertisements were billboards (35.6%) and television (34.4%). The most commonly reported tobacco promotional activities that were noticed by smokers were free gifts when buying cigarettes (23.1%) and free samples of cigarettes (13.9%). Smokers in Changsha were more likely to report noticing tobacco advertisement on billboards (chi2 = 562.474, P < 0.00 1), and on television (chi2 = 265.570, P < 0.001). Smokers in Changsha (chi2 = 58.314, P < 0.001) were more likely to notice tobacco related news and games. A logistic regression analysis showed that the living and education level were related to awareness of tobacco advertisement and promotion. It was universal to see tobacco advertisement and promotions in cities in China but the laws and regulations about tobacco-control were not uniformly executed in different cities. It is necessary to perfect and uniform related laws and regulations.

  10. Effects of different levels of coriander (Coriandrum sativum) seed powder and extract on serum biochemical parameters, microbiota, and immunity in broiler chicks.

    PubMed

    Hosseinzadeh, Hesam; Alaw Qotbi, Ali Ahmad; Seidavi, Alireza; Norris, David; Brown, David

    2014-01-01

    The use of herbs and spices has gained increasing interest as feed additives and possible alternative to antibiotics in poultry production. The effects of using different levels of coriander seed powder or extract on selected blood parameters, intestinal microflora, and immune response of broiler chickens were investigated in this study. A total of 420-day-old broiler chicks were randomly assigned to 7 treatments with 4 replicates and fed for 42 days. Results showed that inclusion of 2.0% coriander powder in broiler diets lowered total cholesterol while blood urea was significantly higher in birds on T4 compared to T1 and T2. Furthermore, there were no treatment effects on Lactobacillus bacteria; however, the population of E. coli was significantly higher in the ileum of chickens fed T0. Noticeable significant improvements of antibody titer against Newcastle, infectious bronchitis, and infectious bursal disease were observed in birds receiving coriander extract in water. Immunoglobulin G antibody against sheep red blood cells showed significant improvement in birds fed T3; likewise, immunoglobulin M was significantly higher in birds on T2 and T3 at 28 d of age. These results revealed that coriander extract or powder can be used as antibiotic alternative in broiler feeds.

  11. Front propagation in a regular vortex lattice: Dependence on the vortex structure.

    PubMed

    Beauvier, E; Bodea, S; Pocheau, A

    2017-11-01

    We investigate the dependence on the vortex structure of the propagation of fronts in stirred flows. For this, we consider a regular set of vortices whose structure is changed by varying both their boundary conditions and their aspect ratios. These configurations are investigated experimentally in autocatalytic solutions stirred by electroconvective flows and numerically from kinematic simulations based on the determination of the dominant Fourier mode of the vortex stream function in each of them. For free lateral boundary conditions, i.e., in an extended vortex lattice, it is found that both the flow structure and the front propagation negligibly depend on vortex aspect ratios. For rigid lateral boundary conditions, i.e., in a vortex chain, vortices involve a slight dependence on their aspect ratios which surprisingly yields a noticeable decrease of the enhancement of front velocity by flow advection. These different behaviors reveal a sensitivity of the mean front velocity on the flow subscales. It emphasizes the intrinsic multiscale nature of front propagation in stirred flows and the need to take into account not only the intensity of vortex flows but also their inner structure to determine front propagation at a large scale. Differences between experiments and simulations suggest the occurrence of secondary flows in vortex chains at large velocity and large aspect ratios.

  12. Activity study of biogenic spherical silver nanoparticles towards microbes and oxidants

    NASA Astrophysics Data System (ADS)

    Hoskote Anand, Kiran Kumar; Mandal, Badal Kumar

    2015-01-01

    The eco-friendly approach for the green synthesis of silver nanoparticles (SNP) using Terminalia bellirica (T. bellirica) fruit extract is reported herein. Initially formation of SNP was noticed through visual color change from yellow to reddish brown and further analyzed by surface plasmonic resonance (SPR) band at 429 nm using UV-Vis spectroscopy. Identification of different polyphenols present in T. bellirica extract was done using High Pressure Liquid Chromatography (HPLC). Aqueous T. bellirica extract contains high amount of gallic acid which is major secondary metabolite responsible for the reduction and stabilization process. It was established by analyses of extracts before and after reduction using HPLC. Formation of spherical SNP was characterized by Transmission Electron Microscopy (TEM) analysis. X-ray Diffraction (XRD) study revealed crystalline nature of SNP. Presence of different functional groups on the surface of SNP was evidenced by Fourier Transform Infrared Spectroscopy (FTIR) study. A plausible mechanism of reduction and stabilization processes involved in the synthesis of stable SNP was also explained based on HPLC and FTIR data. In addition, the synthesized SNP was tested for antibacterial and antioxidant activities. SNP showed good antimicrobial activity against both gram positive (S. aureus) and gram negative (E. coli) bacteria. It also showed good antioxidant activity compared to ascorbic acid as standard antioxidant by using standard DPPH method.

  13. Fast deuterium fractionation in magnetized and turbulent filaments

    NASA Astrophysics Data System (ADS)

    Körtgen, B.; Bovino, S.; Schleicher, D. R. G.; Stutz, A.; Banerjee, R.; Giannetti, A.; Leurini, S.

    2018-04-01

    Deuterium fractionation is considered as an important process to infer the chemical ages of prestellar cores in filaments. We present here the first magneto-hydrodynamical simulations including a chemical network to study deuterium fractionation in magnetized and turbulent filaments, with a line-mass of Mlin = 42 M⊙ pc-1 within a radius of R = 0.1 pc, and their substructures. The filaments typically show widespread deuterium fractionation with average values ≳ 0.01. For individual cores of similar age, we observe the deuteration fraction to increase with time, but also to be independent of their average properties such as density, virial or mass-to-magnetic flux ratio. We further find a correlation of the deuteration fraction with core mass, average H2 density and virial parameter only at late evolutionary stages of the filament and attribute this to the lifetime of the individual cores. Specifically, chemically old cores reveal higher deuteration fractions. Within the radial profiles of selected cores, we notice differences in the structure of the deuteration fraction or surface density, which we can attribute to their different turbulent properties. High deuteration fractions of the order 0.01 - 0.1 may be reached within approximately 200 kyrs, corresponding to two free-fall times, as defined for cylindrical systems, of the filaments.

  14. Fast deuterium fractionation in magnetized and turbulent filaments

    NASA Astrophysics Data System (ADS)

    Körtgen, B.; Bovino, S.; Schleicher, D. R. G.; Stutz, A.; Banerjee, R.; Giannetti, A.; Leurini, S.

    2018-07-01

    Deuterium fractionation is considered as an important process to infer the chemical ages of prestellar cores in filaments. We present here the first magnetohydrodynamical simulations including a chemical network to study deuterium fractionation in magnetized and turbulent filaments, with a line-mass of Mlin = 42 M⊙ pc-1 within a radius of R= 0.1 pc, and their sub-structures. The filaments typically show widespread deuterium fractionation with average values ≳0.01. For individual cores of similar age, we observe the deuteration fraction to increase with time, but also to be independent of their average properties such as density, virial, or mass-to-magnetic flux ratio. We further find a correlation of the deuteration fraction with core mass, average H2 density, and virial parameter only at late evolutionary stages of the filament and attribute this to the lifetime of the individual cores. Specifically, chemically old cores reveal higher deuteration fractions. Within the radial profiles of selected cores, we notice differences in the structure of the deuteration fraction or surface density, which we can attribute to their different turbulent properties. High deuteration fractions of the order of 0.01-0.1 may be reached within approximately 200 kyr, corresponding to two free-fall times, as defined for cylindrical systems, of the filaments.

  15. Physicochemical characterisation and investigation of the bonding mechanisms of API-titanate nanotube composites as new drug carrier systems.

    PubMed

    Sipos, Barbara; Pintye-Hódi, Klára; Kónya, Zoltán; Kelemen, András; Regdon, Géza; Sovány, Tamás

    2017-02-25

    Titanate nanotube (TNT) has recently been explored as a new carrier material for active pharmaceutical ingredients (API). The aim of the present work was to reveal the physicochemical properties of API-TNT composites, focusing on the interactions between the TNTs and the incorporated APIs. Drugs belonging to different Biopharmaceutical Classification System (BCS) classes were loaded into TNTs: diltiazem hydrochloride (BCS I.), diclofenac sodium (BCS II.), atenolol (BCS III.) and hydrochlorothiazide (BCS IV.). Experimental results demonstrated that it is feasible for spiral cross-sectioned titanate nanotubes to carry drugs and maintain their bioactivity. The structural properties of the composites were characterized by a range of analytical techniques, including FT-IR, DSC, TG-MS, etc. The interactions between APIs and TNTs were identified as electrostatic attractions, mainly dominated by hydrogen bonds. Based on the results, it can be stated that the strength of the association depends on the hydrogen donor strength of the API. The drug release of incorporated APIs was evaluated from compressed tablets and compared to that of pure APIs. Differences noticed in the dissolution profiles due to incorporation showed a correlation with the strength of interactions between the APIs and the TNTs observed in the above analytical studies. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Effects of Different Levels of Coriander (Coriandrum sativum) Seed Powder and Extract on Serum Biochemical Parameters, Microbiota, and Immunity in Broiler Chicks

    PubMed Central

    Hosseinzadeh, Hesam; Alaw Qotbi, Ali Ahmad; Seidavi, Alireza; Norris, David; Brown, David

    2014-01-01

    The use of herbs and spices has gained increasing interest as feed additives and possible alternative to antibiotics in poultry production. The effects of using different levels of coriander seed powder or extract on selected blood parameters, intestinal microflora, and immune response of broiler chickens were investigated in this study. A total of 420-day-old broiler chicks were randomly assigned to 7 treatments with 4 replicates and fed for 42 days. Results showed that inclusion of 2.0% coriander powder in broiler diets lowered total cholesterol while blood urea was significantly higher in birds on T4 compared to T1 and T2. Furthermore, there were no treatment effects on Lactobacillus bacteria; however, the population of E. coli was significantly higher in the ileum of chickens fed T0. Noticeable significant improvements of antibody titer against Newcastle, infectious bronchitis, and infectious bursal disease were observed in birds receiving coriander extract in water. Immunoglobulin G antibody against sheep red blood cells showed significant improvement in birds fed T3; likewise, immunoglobulin M was significantly higher in birds on T2 and T3 at 28 d of age. These results revealed that coriander extract or powder can be used as antibiotic alternative in broiler feeds. PMID:25614892

  17. The difference in the effect of glutamate and NO synthase inhibitor on free calcium concentration and Na+, K+-ATPase activity in synaptosomes from various brain regions.

    PubMed

    Avrova, N F; Shestak, K I; Zakharova, I O; Sokolova, T V; Leont'ev, V G

    1999-09-01

    The significant increase of free calcium concentration ([Ca2+]i) was found in rat cerebral cortex synaptosomes and hippocampal crude synaptosomal fraction after their exposure to glutamate. But no change of [Ca2+]i was revealed in cerebellar synaptosomes, the slight increase of [Ca2+]i in striatal synaptosomes was not significant. The presence of Ng-nitro-L-arginine methyl ester (L-NAME) in the incubation medium practically prevented the increase of [Ca2+]i initiated by glutamate in cerebral cortex synaptosomes, but not in hippocampal ones. The significant diminution of [Ca2+]i in the presence of this inhibitor was shown in striatal synaptosomes exposed to glutamate. Na+,K+-ATPase activity is significantly lower in cerebral cortex, striatal and hippocampal synaptosomes exposed to glutamate. L-NAME prevented the inactivation of this enzyme by glutamate. In cerebellar synaptosomes the tendency to the decrease of enzymatic activity in the presence of L-NAME was on the contrary noticed. Thus, the data obtained provide evidence of the protective effect of NO synthase inhibitor in brain cortex and striatal synaptosomes, but not in cerebellar synaptosomes. Synaptosomes appear to be an adequate model to study the regional differences in the mechanism of toxic effect of excitatory amino acids.

  18. 78 FR 52224 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-22

    ... Trader Continuing Education Program (S501) is a computer-based education program developed by many of the... Continuing Education Program, which is developed and maintained by the Securities Industry Regulatory Council... change will authorize the Exchange to administer different CE programs to differently registered...

  19. Earth's Reflection: Albedo

    ERIC Educational Resources Information Center

    Gillette, Brandon; Hamilton, Cheri

    2011-01-01

    When viewing objects of different colors, you might notice that some appear brighter than others. This is because light is reflected differently from various surfaces, depending on their physical properties. The word "albedo" is used to describe how reflective a surface is. The Earth-atmosphere has a combined albedo of about 30%, a number that is…

  20. 75 FR 5865 - Proposed Collection; Comment Request for Notice 2010-6

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ... Notice 2010-6 AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request for comments... Notice 2010-6, Relief and Guidance on Corrections of Certain Failures of a Nonqualified Deferred...). OMB Number: 1545-2164. Notice Number: Notice 2010-6. Abstract: Notice 2010-6 requires a corporation to...

  1. 47 CFR 51.327 - Notice of network changes: Content of notice.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Notice of network changes: Content of notice. 51.327 Section 51.327 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER... Notice of network changes: Content of notice. (a) Public notice of planned network changes must, at a...

  2. 47 CFR 51.325 - Notice of network changes: Public notice requirement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Notice of network changes: Public notice... § 51.325 Notice of network changes: Public notice requirement. (a) An incumbent local exchange carrier (“LEC”) must provide public notice regarding any network change that: (1) Will affect a competing...

  3. 47 CFR 51.325 - Notice of network changes: Public notice requirement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Notice of network changes: Public notice... § 51.325 Notice of network changes: Public notice requirement. (a) An incumbent local exchange carrier (“LEC”) must provide public notice regarding any network change that: (1) Will affect a competing...

  4. 47 CFR 51.327 - Notice of network changes: Content of notice.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Notice of network changes: Content of notice. 51.327 Section 51.327 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER... Notice of network changes: Content of notice. (a) Public notice of planned network changes must, at a...

  5. Boundary Effects and Shear Thickening of Colloidal Suspensions: A study based on measurement of Suspension Microstructure

    NASA Astrophysics Data System (ADS)

    Perera, M. Tharanga D.

    Microstructure is key to understanding rheological behaviors of flowing particulate suspensions. During the past decade, Stokesian Dynamics simulations have been the dominant method of determining suspension microstructure. Structure results obtained numerically reveal that an anisotropic structure is formed under high Peclet (Pe) number conditions. Researchers have used various experimental techniques such as small angle neutron scattering (SANS) and light scattering methods to validate microstructure. This work outlines an experimental technique based on confocal microscopy to study microstructure of a colloidal suspension in an index-matched fluid flowing in a microchannel. High resolution scans determining individual particle locations in suspensions 30-50 vol % yield quantitative results of the local microstructure in the form of the pair distribution function, g(r). From these experimentally determined g(r), the effect of shear rate, quantified by the Peclet number as a ratio of shear and Brownian stress, on the suspension viscosity and normal stress follow that seen in macroscopic rheological measurements and simulations. It is generally believed that shear thickening behavior of colloidal suspensions is driven by the formation of hydroclusters. From measurements of particle locations, hydroclusters are identified. The number of hydroclusters grows exponentially with increasing Pe, and the onset of shear thickening is driven by the increase in formation of clusters having 5-8 particles. At higher Pe, we notice the emergence of 12 or more particle clusters. The internal structure of these hydroclusters has been investigated, and there is some evidence that particles internal to hydroclusters preferentially align along the 45° and 135° axis. Beyond observations of bulk suspension behavior, the influence of boundaries on suspension microstructure is also investigated. Experiments were performed for suspensions flowing over smooth walls, made of glass coverslips, and over rough walls having a high density coating of particles. These results show that there is more order in structure near smooth boundaries while near rough boundaries the structure is similar to that found in the bulk. The relative viscosity and normal stress differences also indicate that boundaries have an effect up as far as 6 particle diameters away from the boundary. Finally, we investigate the microstructure evolvement in a model porous medium and notice that such boundary effects come into play in such real process flows. The confocal microscopy technique also provides us with the advantage of measuring structure in real process flows. We have investigated how the microstructure evolves upstream and downstream in a porous medium. We notice more structure in a high volume fraction suspension and notice anisotropic behavior at regions where shear from the wall of the posts dominate. In other cases, a mixed flow behavior is observed due to collisions between pore surfaces and other particles resulting in a deviation from flow streamlines.

  6. High hydrostatic pressure (HHP) effects on antigenicity and structural properties of soybean β-conglycinin.

    PubMed

    Xi, Jun; He, Mengxue

    2018-02-01

    In this study, the effect of high hydrostatic pressure (HHP) on antigenicity, free sulfhydryl group (SH) content, hydrophobicity (Ho), fluorescence intensity and circular dichroism data of soybean β-conglycinin was studied. The antigenicity of soybean β-conglycinin was decreased significantly at pressures 200-400 MPa. The antigenicity inhibition rate of β-conglycinin declined from 92.72 to 55.15%, after being treated at 400 MPa for 15 min. Results indicated that free sulphydryl (SH) groups and surface Ho of β-conglycinin were significantly increased at pressures 200-400 MPa and 5-15 min, whereas these properties decreased at the treatments above 400 MPa and 15 min. The maximum fluorescence intensity was noticed at 400 MPa and 15 min. The circular dichroism data analysis revealed that the amount of β-turns and unordered structure significantly increased, while the content of α-helix1 and β-strand1 noticeably decreased. These results provide evidence that HHP-induced the structural modification of β-conglycinin and could alter the antigenicity of β-conglycinin.

  7. Antibacterial hydroxypropyl methyl cellulose edible films containing nanoemulsions of Thymus daenensis essential oil for food packaging.

    PubMed

    Moghimi, Roya; Aliahmadi, Atousa; Rafati, Hasan

    2017-11-01

    Edible films containing essential oils (EO) as natural antibacterial agents are promising systems for food preservation. In this work, nanoemulsions of Thymus daenensis EO (wild; F1 and cultivated; F2) were loaded in hydroxyl propyl methyl cellulose (HPMC) films and the effect of different parameters (polymer, plasticizer, and EO concentration) on the film properties were analyzed and optimized. Prepared HPMC films were characterized in terms of EO loading, morphology, mechanical properties, and the antibacterial activity. The results of SEM showed uniform incorporation of nanoemulsions into the edible film. Investigation of the mechanical properties of two edible films revealed a plasticizing effect of T. daenensis EO on the films. Also, edible films had noticeable antimicrobial activity against selected microorganisms, i.e. 47.0±2.5mm and 22.6±0.5mm zone of inhibition against S. aureus for films containing F1 and F2, respectively. Incorporation of nanoemulsions into the HPMC films can be used for active food preservation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Quantum dynamical simulation of the scattering of Ar from a frozen LiF(100) surface based on a first principles interaction potential

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Azuri, Asaf; Pollak, Eli, E-mail: eli.pollak@weizmann.ac.il

    2015-07-07

    In-plane two and three dimensional diffraction patterns are computed for the vertical scattering of an Ar atom from a frozen LiF(100) surface. Suitable collimation of the incoming wavepacket serves to reveal the quantum mechanical diffraction. The interaction potential is based on a fit to an ab initio potential calculated using density functional theory with dispersion corrections. Due to the potential coupling found between the two horizontal surface directions, there are noticeable differences between the quantum angular distributions computed for two and three dimensional scattering. The quantum results are compared to analogous classical Wigner computations on the same surface and withmore » the same conditions. The classical dynamics largely provides the envelope for the quantum diffractive scattering. The classical results also show that the corrugation along the [110] direction of the surface is smaller than along the [100] direction, in qualitative agreement with experimental observations of unimodal and bimodal scattering for the [110] and [100] directions, respectively.« less

  9. Macroscopic behavior and microscopic magnetic properties of nanocarbon

    NASA Astrophysics Data System (ADS)

    Lähderanta, E.; Ryzhov, V. A.; Lashkul, A. V.; Galimov, D. M.; Titkov, A. N.; Matveev, V. V.; Mokeev, M. V.; Kurbakov, A. I.; Lisunov, K. G.

    2015-06-01

    Here are presented investigations of powder and glass-like samples containing carbon nanoparticles, not intentionally doped and doped with Ag, Au and Co. The neutron diffraction study reveals an amorphous structure of the samples doped with Au and Co, as well as the magnetic scattering due to a long-range FM order in the Co-doped sample. The composition and molecular structure of the sample doped with Au is clarified with the NMR investigations. The temperature dependence of the magnetization, M (T), exhibits large irreversibility in low fields of B=1-7 mT. M (B) saturates already above 2 T at high temperatures, but deviates from the saturation behavior below 50 (150 K). Magnetic hysteresis is observed already at 300 K and exhibits a power-law temperature decay of the coercive field, Bc (T). The macroscopic behavior above is typical of an assembly of partially blocked magnetic nanoparticles. The values of the saturation magnetization, Ms, and the blocking temperature, Tb, are obtained as well. However, the hysteresis loop in the Co-doped sample differs from that in other samples, and the values of Bc and Ms are noticeably increased.

  10. Orbital ordering-driven ferromagnetism in LaCoO3 nanowires

    NASA Astrophysics Data System (ADS)

    Wang, Yang; Fan, Hong Jin

    2010-09-01

    The structure and magnetic properties of LaCoO3 nanowires are investigated as a function of the diameter in the temperature range of 5-300 K. Ferromagnetism below 85 K is observed in these nanowires, in agreement with the recent observations in LaCoO3 epitaxial thin films and nanoparticles. With the diameter of nanowires decreasing, the unit-cell volume increases, while both the global and local structural distortions lessen, accompanied by the gradual enhancement of ferromagnetism. The structure analysis reveals that LaCoO3 nanowires exhibit a monoclinic distorted structure with I2/a space group in the entire investigated temperature range. Different from bulks, there is no clear spin-state transition occurring with temperature in LaCoO3 nanowires. There exists a noticeable Jahn-Teller (JT) distortion in the nanowires even at the lowest temperature, namely, orbital-ordered JT active Co3+ ions with intermediate-spin (IS) state persist at low temperatures, which is not observed in bulk LaCoO3. These results indicate that the ferromagnetism in the nanowires is driven by the orbital ordering of IS Co3+.

  11. Effects of protein conformational flexibilities and electrostatic interactions on the low-frequency vibrational spectrum of hydration water.

    PubMed

    Pal, Somedatta; Bandyopadhyay, Sanjoy

    2013-05-16

    The conformational flexibility of a protein and its ability to form hydrogen bonds with water are expected to influence the microscopic properties of water layer hydrating the protein. Detailed molecular dynamics simulations with an aqueous solution of the globular protein barstar have been carried out to explore such influence on the low-frequency vibrational spectrum of the hydration water molecules. The calculations reveal that enhanced degree of confinement at the protein surface on freezing its local motions leads to increasingly restricted oscillatory motions of the hydration water molecules as evident from larger blue shifts of the corresponding band. Interestingly, conformational fluctuations of the protein and electrostatic component of its interaction with the solvent have been found to affect the transverse and longitudinal oscillations of hydration water molecules in a nonuniform manner. It is further noticed that the distributions of the low-frequency modes for the water molecules hydrogen bonded to the residues of different segments of the protein are heterogeneously altered. The effect is more around the frozen protein matrix and agrees well with slower protein-water hydrogen bond relaxations.

  12. Accumulation of Phenylpropanoids by White, Blue, and Red Light Irradiation and Their Organ-Specific Distribution in Chinese Cabbage (Brassica rapa ssp. pekinensis).

    PubMed

    Kim, Yeon Jeong; Kim, Yeon Bok; Li, Xiaohua; Choi, Su Ryun; Park, Suhyoung; Park, Jong Seok; Lim, Yong Pyo; Park, Sang Un

    2015-08-05

    This study investigated optimum light conditions for enhancing phenylpropanoid biosynthesis and the distribution of phenylpropanoids in organs of Chinese cabbage (Brassica rapa ssp. pekinensis). Blue light caused a high accumulation of most phenolic compounds, including p-hydroxybenzoic acid, ferulic acid, quercetin, and kaempferol, at 12 days after irradiation (DAI). This increase was coincident with a noticeable increase in expression levels of BrF3H, BrF3'H, BrFLS, and BrDFR. Red light led to the highest ferulic acid content at 12 DAI and to elevated expression of the corresponding genes during the early stages of irradiation. White light induced the highest accumulation of kaempferol and increased expression of BrPAL and BrDFR at 9 DAI. The phenylpropanoid content analysis in different organs revealed organ-specific accumulation of p-hydroxybenzoic acid, quercetin, and kaempferol. These results demonstrate that blue light is effective at increasing phenylpropanoid biosynthesis in Chinese cabbage, with leaves and flowers representing the most suitable organs for the production of specific phenylpropanoids.

  13. Investigation by response surface methodology of the combined effect of pH and composition of water-methanol mixtures on the stability of curcuminoids.

    PubMed

    D'Archivio, Angelo Antonio; Maggi, Maria Anna

    2017-03-15

    Response surface methodology, coupled to a full factorial three-level experimental design, was applied to investigate the combined influence of pH (between 7.0 and 8.6) and composition of methanol-water mixtures (between 30 and 70% v/v of methanol content) on the stability of curcumin and its analogues demethoxycurcumin and bisdemethoxycurcumin. The response plots revealed that addition of methanol noticeably improved the stability of curcuminoids, this effect being both pH- and structure-dependent. In the central point of the experimental domain, half-life times of curcumin, demethoxycurcumin and bisdemethoxycurcumin were 3.8±0.2, 27±2 and 251±17h, respectively. Stability of curcuminoids increased at lower pH and higher methanol content and decreased in the opposite vertex of the experimental domain. These results can be interpreted by assuming that addition of methanol to water produces a different variation of pH of the medium and apparent pKa values of the ionisable groups of curcuminoids. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Microwave-assisted nitric acid treatment of sepiolite and functionalization with polyethylenimine applied to CO2 capture and CO2/N2 separation

    NASA Astrophysics Data System (ADS)

    Vilarrasa-García, E.; Cecilia, J. A.; Bastos-Neto, M.; Cavalcante, C. L.; Azevedo, D. C. S.; Rodríguez-Castellón, E.

    2017-07-01

    Sepiolite was treated in HNO3 solutions with the assistance of microwave radiation. This treatment caused the progressive depletion of Mg2+, the gradual degradation of the sepiolite structure and the formation of an amorphous silica phase, which contributes to a noticeable increase of the surface area. The use of microwaves during acid treatment, after few minutes, led to materials with similar SBET to those obtained after 48 h with conventional heating methods. The influence of mineralogical impurities, crystallinity and chemical composition in the reactivity of sepiolite to this treatment was also studied. The obtained materials were impregnated with polyethylenimine and assessed for CO2 capture and CO2/N2 selectivity at different temperatures. Experimental equilibrium data were fitted to Langmuir and Sips models. The adsorption data revealed that sepiolite can be an interesting adsorbent for CO2 capture, achieving a capacity of 1.70 mmol g-1 at 338 K and 1 bar, providing a high CO2/N2 selectivity (440 mol CO2/mol N2).

  15. Are the TTAGG and TTAGGG telomeric repeats phylogenetically conserved in aculeate Hymenoptera?

    NASA Astrophysics Data System (ADS)

    Menezes, Rodolpho S. T.; Bardella, Vanessa B.; Cabral-de-Mello, Diogo C.; Lucena, Daercio A. A.; Almeida, Eduardo A. B.

    2017-10-01

    Despite the (TTAGG)n telomeric repeat supposed being the ancestral DNA motif of telomeres in insects, it was repeatedly lost within some insect orders. Notably, parasitoid hymenopterans and the social wasp Metapolybia decorata (Gribodo) lack the (TTAGG)n sequence, but in other representatives of Hymenoptera, this motif was noticed, such as different ant species and the honeybee. These findings raise the question of whether the insect telomeric repeat is or not phylogenetically predominant in Hymenoptera. Thus, we evaluated the occurrence of both the (TTAGG)n sequence and the vertebrate telomere sequence (TTAGGG)n using dot-blotting hybridization in 25 aculeate species of Hymenoptera. Our results revealed the absence of (TTAGG)n sequence in all tested species, elevating the number of hymenopteran families lacking this telomeric sequence to 13 out of the 15 tested families so far. The (TTAGGG)n was not observed in any tested species. Based on our data and compiled information, we suggest that the (TTAGG)n sequence was putatively lost in the ancestor of Apocrita with at least two subsequent independent regains (in Formicidae and Apidae).

  16. 76 FR 7623 - Notice To Rescind a Notice of Intent To Prepare an Environmental Impact Statement on Seattle...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-10

    ... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Notice To Rescind a Notice of Intent... Transportation. ACTION: Notice to rescind a notice of intent to prepare an environmental impact statement... Washington State Department of Transportation, Ferries Division (WSF), are rescinding the Notice of Intent...

  17. 12 CFR 222.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... SYSTEM FAIR CREDIT REPORTING (REGULATION V) Affiliate Marketing § 222.26 Delivery of opt-out notices. (a... notice if the affiliate providing the notice: (1) Hand-delivers a printed copy of the notice to the... the affiliate providing the notice; or (4) Posts the notice on the Internet Web site at which the...

  18. Snapshots of mathematics teacher noticing during task design

    NASA Astrophysics Data System (ADS)

    Choy, Ban Heng

    2016-09-01

    Designing a mathematically worthwhile task is critical for promoting students' reasoning. To improve task design skills, teachers often engage in collaborative lesson planning activities such as lesson study. However, to learn from the process of lesson study, it is important for teachers to notice productively the concepts, students' confusion and the design of the task. But what researchers mean by productive noticing varies. In this article, I present the FOCUS Framework which highlights two characteristics of productive noticing: having an explicit focus for noticing and focusing noticing through pedagogical reasoning. Using these two characteristics, I develop snapshots of noticing as a representation of practice to present a fine-grained analysis of teacher noticing. Through vignettes of teachers discussing the design of a task to teach fractions, I illustrate how two teachers' noticing can be analysed and represented using snapshots of noticing. To conclude, I highlight what snapshots of noticing tell us about a teacher's noticing and suggest ways to use these snapshots in future studies of noticing.

  19. Non-target screening analyses of organic contaminants in river systems as a base for monitoring measures

    NASA Astrophysics Data System (ADS)

    Schwarzbauer, J.

    2009-04-01

    Organic contaminants discharged to the aquatic environment exhibit a high diversity with respect to their molecular structures and the resulting physico-chemical properties. The chemical analysis of anthropogenic contamination in river systems is still an important feature, especially with respect to (i) the identification and structure elucidation of novel contaminants, (ii) to the characterisation of their environmental behaviour and (iii) to their risk for natural systems. A huge proportion of riverine contamination is caused by low-molecular weight organic compounds, like pesticides plasticizers, pharmaceuticals, personal care products, technical additives etc. Some of them, like PCB or PAH have already been investigated thoroughly and, consequently, their behaviour in aqueous systems is very well described. Although analyses on organic substances in river water traditionally focused on selected pollutants, in particular on common priority pollutants which are monitored routinely, the occurrence of further contaminants, e.g. pharmaceuticals, personal care products or chelating agents has received increasing attention within the last decade. Accompanied, screening analyses revealing an enormous diversity of low-molecular weight organic contaminants in waste water effluents and river water become more and more noticed. Since many of these substances have been rarely noticed so far, it will be an important task for the future to study their occurrence and fate in natural environments. Further on, it should be a main issue of environmental studies to provide a comprehensive view on the state of pollution of river water, in particular with respect to lipophilic low molecular weight organic contaminants. However, such non-target-screening analyses has been performed only rarely in the past. Hence, we applied extended non-target screening analyses on longitudinal sections of the rivers Rhine, Rur and Lippe (Germany) on the base of GC/MS analyses. The investigations revealed complex pattern of anthropogenic contaminants comprising a lot of still unnoticed pollutants (e.g. specific sulfones, trifluoromethyl substituted substances, nitrogen heterocycles etc.) or still unidentified compounds (such as selected brominated aromatics) of obviously high environmental relevance. In this presentation, a selection of several different contaminants will be discussed in detail comprising their emission sources, their emission behaviour, their fate within the river water bodies and in particular their structural properties. Generally. this investigation demonstrated the need to expand our analytical focus on a broader spectrum of organic contaminants, in particular to build up an adapted base for advanced monitoring studies.

  20. 77 FR 21724 - Certain Orange Juice From Brazil: Preliminary Results of Antidumping Duty Administrative Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... if they are made at different marketing stages (or their equivalent). See 19 CFR 351.412(c)(2... that there is a difference in the stages of marketing. Id., see also Notice of Final Determination of... sales were at different stages in the marketing process than the U.S. sales, we reviewed the...

  1. 75 FR 73042 - 1-Hydroxyethylidene-1,1-Diphosphonic Acid From India: Preliminary Results of Antidumping Duty...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    ... if they are made at different marketing stages (or their equivalent). See 19 CFR 351.412(c)(2... that there is a difference in the stages of marketing. See id.; see also Notice of Final Determination... sales were at different stages in the marketing process than the U.S. sales, we reviewed the...

  2. 75 FR 973 - Certain Welded Stainless Steel Pipes From the Republic of Korea: Preliminary Results of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-07

    ... same LOT as CEP. Sales are made at different LOTs if they are made at different marketing stages (or... marketing. Id; see also Notice of Final Determination of Sales at Less than Fair Value: Certain Cut-to...). In order to determine whether the home market sales were at different stages in the marketing process...

  3. What's the Difference Between Vocal Cord Dysfunction and Asthma?

    MedlinePlus

    ... of Privacy Practices Notice of Nondiscrimination Manage Cookies Advertising Mayo Clinic is a not-for-profit organization and proceeds from Web advertising help support our mission. Mayo Clinic does not ...

  4. 47 CFR 51.331 - Notice of network changes: Timing of notice.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Notice of network changes: Timing of notice. 51... Notice of network changes: Timing of notice. (a) An incumbent LEC shall give public notice of planned... procure from another entity, any product the design of which affects or relies on a new or changed network...

  5. 47 CFR 51.331 - Notice of network changes: Timing of notice.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Notice of network changes: Timing of notice. 51... Notice of network changes: Timing of notice. (a) An incumbent LEC shall give public notice of planned... procure from another entity, any product the design of which affects or relies on a new or changed network...

  6. Apparent solubility of hydroxyapatite in aqueous medium and its influence on the morphology of nanocrystallites with precipitation temperature.

    PubMed

    Prakash, K H; Kumar, R; Ooi, C P; Cheang, P; Khor, K A

    2006-12-19

    Two differing wet-chemical synthesis routes, Ca(OH)2 + H3PO4 and CaCl2 + Na3PO4/NaOH, were used to prepare hydroxyapatite (HA) at various temperatures ranging from 30 to 95 degrees C. The electrical conductivity of the solution was measured at regular intervals of time during H3PO4 and Na3PO4 addition to the suspension/solution containing Ca2+ ions. The rate of change of conductivity is used to note the end point of the reaction. X-ray diffraction of the dried, precipitated particles revealed HA as the predominant phase, and the FTIR spectroscopy studies indicated the presence of CO3(2-) groups which substituted PO4(3-) groups in the HA lattice (B-type). FESEM observations revealed that the aspect ratio of the particles decreased with increasing precipitation reaction temperature in one system [Ca(OH)2 + H3PO4] and in the other system it increased with increasing temperature. The changes in the morphology with temperature were analyzed through conductivity measurements and the thermochemical properties of the reaction systems. Conductivity measurements showed that the concentration of dissolved ions at the end point of the reaction between Ca(OH)2 and H3PO4 increased, indicating an increased apparent solubility of HA with increasing temperature, whereas the end-point conductivity did not increase noticeably in the other reaction system.

  7. Study of Aging-Induced Degradation of Fracture Resistance of Alloy 617 Toward High-Temperature Applications

    NASA Astrophysics Data System (ADS)

    Singh, Aditya Narayan; Moitra, A.; Bhaskar, Pragna; Sasikala, G.; Dasgupta, Arup; Bhaduri, A. K.

    2017-07-01

    For the Alloy 617, the effect of aging on the fracture energy degradation has been investigated after aging for different time periods at 1023 K (750 °C). A sharp reduction in impact energy (by 55 pct vis-à-vis the as-received material) after 1000 hours of aging, as evaluated from room-temperature Charpy impact tests, has been observed. Further aging up to 10,000 hours has led to a degradation of fracture energy up to 78 pct. Fractographic examinations using scanning electron microscopy (SEM) have revealed a change in fracture mode from fibrous-ductile for the un-aged material to intergranular mode for the aged one. The extent of intergranular fracture increases with the increasing aging time, indicating a tendency of the material to undergo grain boundary embrittlement over long-term aging. Analysis of the transmission electron microscopy (TEM) micrographs along with selected area diffraction (SAD) patterns for the samples aged at 10,000 hours revealed finely dispersed γ' precipitates of size 30 to 40 nm, rich in Al and Ti, along with extensive precipitation of M23C6 at the grain boundaries. In addition, the presence of Ni3Si of size in the range of 110 to 120 nm also has been noticed. The extensive precipitation of M23C6 at the grain boundaries have been considered as a major reason for aging-induced embrittlement of this material.

  8. Deep Sequence Analysis of AgoshRNA Processing Reveals 3' A Addition and Trimming.

    PubMed

    Harwig, Alex; Herrera-Carrillo, Elena; Jongejan, Aldo; van Kampen, Antonius Hubertus; Berkhout, Ben

    2015-07-14

    The RNA interference (RNAi) pathway, in which microprocessor and Dicer collaborate to process microRNAs (miRNA), was recently expanded by the description of alternative processing routes. In one of these noncanonical pathways, Dicer action is replaced by the Argonaute2 (Ago2) slicer function. It was recently shown that the stem-length of precursor-miRNA or short hairpin RNA (shRNA) molecules is a major determinant for Dicer versus Ago2 processing. Here we present the results of a deep sequence study on the processing of shRNAs with different stem length and a top G·U wobble base pair (bp). This analysis revealed some unexpected properties of these so-called AgoshRNA molecules that are processed by Ago2 instead of Dicer. First, we confirmed the gradual shift from Dicer to Ago2 processing upon shortening of the hairpin length. Second, hairpins with a stem larger than 19 base pair are inefficiently cleaved by Ago2 and we noticed a shift in the cleavage site. Third, the introduction of a top G·U bp in a regular shRNA can promote Ago2-cleavage, which coincides with a loss of Ago2-loading of the Dicer-cleaved 3' strand. Fourth, the Ago2-processed AgoshRNAs acquire a short 3' tail of 1-3 A-nucleotides (nt) and we present evidence that this product is subsequently trimmed by the poly(A)-specific ribonuclease (PARN).

  9. Deep Sequence Analysis of AgoshRNA Processing Reveals 3' A Addition and Trimming

    PubMed Central

    Harwig, Alex; Herrera-Carrillo, Elena; Jongejan, Aldo; van Kampen, Antonius Hubertus; Berkhout, Ben

    2015-01-01

    The RNA interference (RNAi) pathway, in which microprocessor and Dicer collaborate to process microRNAs (miRNA), was recently expanded by the description of alternative processing routes. In one of these noncanonical pathways, Dicer action is replaced by the Argonaute2 (Ago2) slicer function. It was recently shown that the stem-length of precursor-miRNA or short hairpin RNA (shRNA) molecules is a major determinant for Dicer versus Ago2 processing. Here we present the results of a deep sequence study on the processing of shRNAs with different stem length and a top G·U wobble base pair (bp). This analysis revealed some unexpected properties of these so-called AgoshRNA molecules that are processed by Ago2 instead of Dicer. First, we confirmed the gradual shift from Dicer to Ago2 processing upon shortening of the hairpin length. Second, hairpins with a stem larger than 19 base pair are inefficiently cleaved by Ago2 and we noticed a shift in the cleavage site. Third, the introduction of a top G·U bp in a regular shRNA can promote Ago2-cleavage, which coincides with a loss of Ago2-loading of the Dicer-cleaved 3' strand. Fourth, the Ago2-processed AgoshRNAs acquire a short 3' tail of 1–3 A-nucleotides (nt) and we present evidence that this product is subsequently trimmed by the poly(A)-specific ribonuclease (PARN). PMID:26172504

  10. Barriers to Access to Sterile Syringes as Perceived by Pharmacists and Injecting Drug Users: Implications for Harm Reduction in Lebanon.

    PubMed

    Ghaddar, Ali; Nassar, Karine; Elsoury, Ghadier

    2017-09-19

    Access to sterile syringes to injecting drug users (IDU) reduces sharing behavior and prevents the transmission of HIV. To describe the barriers to access to sterile syringes for IDUs in Lebanon from the perspectives of pharmacists and IDUs. in this qualitative study conducted in Lebanon, data were collected from 72 syringe purchase tests at pharmacies, 64 interviewees with pharmacists and 2 focus groups with injecting drug users. Two independent researchers analyzed the verbatim transcripts. Results revealed that pharmacists often deny access to sterile syringes to IDUs who are frequently stigmatized and intimidated at pharmacies. While no large gender differences in pharmacists' attitudes and practices were observed, inequalities in syringe access were noticed with men IDUs more often denied purchase. Pharmacists had several barriers to sell syringes to IDUs including fear of disease spread, increased drug use, inappropriately discarded syringes, staff and customer safety, and business concerns. IDUs had several challenges to purchase syringes including stigmatization, intimidation, physical harassment, concern to reveal identity, fear of arrest and syringe price abuse. Identifying the barriers to and facilitators of access to sterile syringes to IDUs is important to guide the development of efficient policies. Findings implicate the importance of empowering IDUs to purchase syringes at pharmacies through reducing the negative attitude towards IDUs and strengthening pharmacists' role in the promotion of health of IDUs. Findings also suggest that the habit of syringe sharing would decrease if the legal and cultural barriers to access are reduced.

  11. A proteomic and ultrastructural characterization of Aspergillus fumigatus' conidia adaptation at different culture ages.

    PubMed

    Anjo, Sandra I; Figueiredo, Francisco; Fernandes, Rui; Manadas, Bruno; Oliveira, Manuela

    2017-05-24

    The airborne fungus Aspergillus fumigatus is one of the most common agents of human fungal infections with a remarkable impact on public health. However, A. fumigatus conidia atmospheric resistance and longevity mechanisms are still unknown. Therefore, in this work, the processes underlying conidial adaptation were studied by a time course evaluation of the proteomics and ultrastructural changes of A. fumigatus' conidia at three time-points selected according to relevant changes previously established in conidial survival rates. The proteomics characterization revealed that conidia change from a highly active metabolic to a dormant state, culminating in cell autolysis as revealed by the increased levels of hydrolytic enzymes. Structural characterization corroborates the proteomics data, with noticeable changes observed in mitochondria, nucleus and plasma membrane ultrastructure, accompanied by the formation of autophagic vacuoles. These changes are consistent with both apoptotic and autophagic processes, and indicate that the changes in protein levels may anticipate those in cell morphology. The findings presented in this work not only clarify the processes underlying conidial adaptation to nutrient limiting conditions but can also be exploited for improving infection control strategies and in the development of new therapeutical drugs. Additionally, the present study was deposited in a public database and thus, it may also be a valuable dataset to be used by the scientific community as a tool to understand and identified other potential targets associated with conidia resistance. Copyright © 2017. Published by Elsevier B.V.

  12. Prenatal care in your third trimester

    MedlinePlus

    ... that you continue to: Eat well -- including protein rich foods and vegetables frequently and in small amounts ... closer to your due date, and your baby grows bigger, you should notice a different pattern of ...

  13. Bipolar Treatment: Are Bipolar I and Bipolar II Treated Differently?

    MedlinePlus

    ... of Privacy Practices Notice of Nondiscrimination Manage Cookies Advertising Mayo Clinic is a not-for-profit organization and proceeds from Web advertising help support our mission. Mayo Clinic does not ...

  14. Fast mode decision based on human noticeable luminance difference and rate distortion cost for H.264/AVC

    NASA Astrophysics Data System (ADS)

    Li, Mian-Shiuan; Chen, Mei-Juan; Tai, Kuang-Han; Sue, Kuen-Liang

    2013-12-01

    This article proposes a fast mode decision algorithm based on the correlation of the just-noticeable-difference (JND) and the rate distortion cost (RD cost) to reduce the computational complexity of H.264/AVC. First, the relationship between the average RD cost and the number of JND pixels is established by Gaussian distributions. Thus, the RD cost of the Inter 16 × 16 mode is compared with the predicted thresholds from these models for fast mode selection. In addition, we use the image content, the residual data, and JND visual model for horizontal/vertical detection, and then utilize the result to predict the partition in a macroblock. From the experimental results, a greater time saving can be achieved while the proposed algorithm also maintains performance and quality effectively.

  15. Nano/microstructure and optical properties of ZnO particles precipitated from zinc acetylacetonate

    NASA Astrophysics Data System (ADS)

    Petrović, Željka; Ristić, Mira; Musić, Svetozar; Fabián, Martin

    2015-06-01

    The influence of experimental conditions on the nano/microstructure and optical properties of ZnO particles produced by rapid hydrolysis of zinc acetylacetonate, followed by aging of the precipitation system at 160 °C, was investigated. Samples were characterized by XRD, FE scanning electron microscopy (FE-SEM), FT-IR, UV/Vis/NIR and photoluminescence (PL) spectroscopies. XRD patterns of all samples were assigned to the hexagonal ZnO phase (wurtzite-type), as well as the corresponding FT-IR spectra. FE-SEM inspection showed a high dependence of the ZnO nano/microstructure on the chemical composition of the reaction mixture and autoclaving time after the rapid hydrolysis of zinc acetylacetonate. Microstructural differences were noticed between C2H5OH/H2O and H2O media, as well as under the influence of NH4OH addition. Measurements of nanocrystallite sizes showed no significant preferential orientation in the (1 0 0) and (0 0 2) directions relative to the (1 0 1) and (1 1 0) directions. Somewhat smaller crystallite sizes were noticed for ZnO samples synthesized by adding the NH4OH solution. Dissolution/recrystallization of ZnO particles played an important role in the formation of different ZnO nano/microstructures. The band gap values for prepared ZnO samples were calculated on the basis of recorded UV/Vis spectra. PL spectra were recorded for ZnO samples in powder form and their suspensions in pure ethanol. Noticed differences are discussed.

  16. Monitoring and assessment of environmental disturbance on natural Gambusia affinis populations--histopathological analysis.

    PubMed

    Annabi, Ali; Said, Khaled; Messaoudi, Imed

    2015-06-01

    Physiological investigations are often used to assess the toxic effects of aquatic pollutants in fish and to establish criteria for water quality. In the present study, we tend to investigate the growth performance, skeletal abnormalities, and histological alterations noticed in three natural populations of the mosquitofish Gambusia affinis captured from three estuary sites. The analysis of growth performance demonstrated that the studied populations showed different growth patterns. Additionally, various types of skeletal deformities were observed, and the most commonly affected were the hemal and pre-hemal regions of fishes. For the histological study, gills, liver, and kidney tissues were selected for field monitoring. The major alterations observed in gill tissues were partial fusion of adjacent secondary lamellae, hypertrophy of epithelial cells, and disorganization of pillar cells in many areas of the secondary lamellae. In the liver, significant desquamation of tissues, congestion of the central hepatic vein, and hypertrophy of hepatocytes were noticed. For the kidney tissue, the frequencies of histological alterations showed a significant difference between the studied sites. Moreover, the histological aberrations consisted mainly in glomerule alteration and vacuolation of tubular epithelial cells. Taken together, these data support the hypothesis that the physiological alterations noticed in the present investigation are indicators of sensitivity towards environmental disturbance.

  17. Making communication research matter: what do patients notice, what do patients want, and what do patients need?

    PubMed

    Epstein, Ronald M

    2006-03-01

    To explore limitations of current communication theory by considering different perspectives of researchers, clinicians, patients and teachers of communication. Theory development based on limitations of the current communication research literature due to inconsistencies between patient reports and observed communication behavior. While researchers focus on the mechanics and techniques of communication, patients seek relationships in which they experience trust, the right amount of autonomy, caring, and expertise. Patients', physicians', and communication experts' perspectives do not always define the same problems and often point to different solutions. In addition to studying clinician behaviors and patient perceptions of care, communication research should focus on five additional factors: what patients notice, want and need, and how their perspectives differ from those of physicians and researchers; the context, including illness severity and type and family influences; how complex health systems facilitate and impede communication; patients' influences on physician communication behavior; and habits of mind that promote attentive care.

  18. 77 FR 70413 - Information Collection; Flathead and McKenzie Rivers and McKenzie National Recreational Trail...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... McKenzie National Recreational Trail Visitor Surveys AGENCY: Forest Service, USDA. ACTION: Notice; request... Recreational Trail. Because of the differences in the issues on each River and the need for different... Rivers and McKenzie National Recreational Trail by in-person, written surveys which will be administered...

  19. 75 FR 3464 - Notice of a Regional Project Waiver of Section 1605 (Buy American) of the American Recovery and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... County desired to, ``standardize on a single brand of submersible pumps for wastewater pump stations in... inventory, service, maintenance, and engineering associated with using several different brands.'' This is a... associated with using several different brands of pumps. Additionally, according to the County...

  20. 76 FR 1144 - CenterPoint Energy-Mississippi River Transmission Corporation; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ... that on December 15, 2010, CenterPoint Energy- Mississippi River Transmission Corporation (MRT), 1111... Lincoln Parish, Louisiana. MRT states that the Inventory Verification Study disclosed a difference of approximately 1.2 Bcf less cushion gas than the accounting records. MRT avers that the differences were due to...

  1. 78 FR 5535 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... and different business model for electronic orders as opposed to open outcry orders leads the Exchange to offer a rebate in order to compete with other exchanges for electronic orders. The business models... because the competitive pressures from other exchanges in electronic orders and different business model...

  2. Impact of Using CALL on Iranian EFL Learners' Vocabulary Knowledge

    ERIC Educational Resources Information Center

    Yunus, Melor Md; Salehi, Hadi; Amini, Mahdi

    2016-01-01

    Computer Assisted Language Learning (CALL) integration in EFL contexts has intensified noticeably in recent years. This integration might be in different ways and for different purposes such as vocabulary acquisition, grammar learning, phonology, writing skills, etc. More explicitly, this study is an attempt to explore the effect of using CALL on…

  3. 76 FR 35924 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... places specified in Item IV below. The self-regulatory organization has prepared summaries, set forth in... introduce three additional routing strategies to the rule. These routing strategies included ROBB and ROCO... User.\\5\\ The difference between the latter two routing strategies lies in the difference in the System...

  4. 40 CFR 164.21 - Contents of a denial of registration, notice of intent to cancel a registration, or notice of...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., notice of intent to cancel a registration, or notice of intent to change a classification. 164.21 Section... denial of registration, notice of intent to cancel a registration, or notice of intent to change a classification. (a) Contents. The denial of registration or a notice of intent to cancel a registration or to...

  5. From prescriptions to drug use periods - things to notice.

    PubMed

    Tanskanen, Antti; Taipale, Heidi; Koponen, Marjaana; Tolppanen, Anna-Maija; Hartikainen, Sirpa; Ahonen, Riitta; Tiihonen, Jari

    2014-11-14

    Electronic prescription registers provide a vast data source for pharmacoepidemiological research. Prescriptions as such are not suitable for all research purposes; e.g., studying concurrent use of different drugs or adverse drug events during current use. For those purposes, data on dispensed prescriptions needs to be transformed to periods of drug use. We used 3,828,292 dispensed prescriptions claimed between 1 January 2002 and 31 December 2009 for 28,093 persons with Alzheimer's disease. Examples of drug use histories are presented to discuss different aspects that should be noticed when using register-based data consisting of drug purchases. There is no simple method for correctly transforming dispensed prescriptions to periods of drug use that is usable for all drugs and drug users. Fixed assumptions of daily dose (in defined daily doses, tablets or other units) and fixed time windows should be used with caution and adjusted for different drug use patterns. We recommend that when transforming prescription drug purchases to drug use periods personal dose, purchasing pattern and other behavioral differences between patients should be taken into account.

  6. Massive Pulmonary Calculi Embolism: A Novel Complication of Pneumatic Lithotripsy: A Case Report.

    PubMed

    Zhang, Lin; Zhou, Yiwu

    2015-07-01

    Pneumatic lithotripsy is a minimally invasive technique mainly for the treatment of urinary staghorn stones. Previous literatures have reported some therapeutic complications during or after this procedure, but calculi embolism has not been mentioned before.We report here a fatal case of calculi-induced pulmonary embolism in an adult woman who underwent pneumatic lithotripsy. An autopsy did not reveal any evidence of pulmonary embolism. However, light microscopy revealed noticeable presence of calculi in pulmonary arterioles and capillaries, as evidenced by environmental scanning electron microscope and energy dispersive X-ray analysis. The primary determinants of calculi embolism include intrarenal pressure, and volume and viscosity of the calculi fragments formation. Vascular intravasation of smashed calculi might increase pulmonary vascular resistance and hypoxemia and decrease cardiac output.This case report intends to provide information for clinicians to consider the probability of intraoperative calculi embolism during lithotripsies when patients develop typical symptoms of acute pulmonary embolism.

  7. Atomic origins of water-vapour-promoted alloy oxidation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Luo, Langli; Su, Mao; Yan, Pengfei

    The presence of water vapor, intentional or unavoidable, is crucial to many materials applications, such as steam generator, turbine engine, fuel cell, catalyst, and corrosion 1-6. Phenomenologically, water vapor has been noticed to accelerate oxidation of metals/alloys 7,8, however, the atomistic mechanisms remain elusive. Herein, through direct in situ atomic-scale transmission electron microscopy observation and density functional theory calculation, we reveal that water vapor enhanced oxidation of Ni-Cr alloy is associated with proton dissolution promoted vacancy formation, migration and clustering. Protons derived from water dissociation occupy interstitial position in the oxide lattice, which consequently leads to the lowering of bothmore » vacancy formation energy and the cation diffusion barrier. The atomic scale observations reveal a water vapor derived proton mediated oxide growth mechanism, which provides insights for reckoning many technological processes concerning materials in moist environment at elevated temperatures.« less

  8. [Persistence of the primordial vitreous body and buphthalmos].

    PubMed

    Cernea, P; Simionescu, C; Bosun, I

    1995-01-01

    Persistence of the hyperplasic primordial vitreous body is determined by a deletion of embryonal development of the vitreous body and of the hyaloid vascular system. Infant aged 3.5 years presents persistence of primordial vitreous body with crystalline dislocation in the camera aquosa and secondary buphthalmos of the left eye and microphthalmos with dislocation of the crystalline in the vitreous body of the right eye. At the back of the right eye we noticed a whitish mass, richly vascularized with vestiges from the hyaloid artery, but the posterior half of the vitreous cavity is filled with microscopic blood; the fibrovascular membrane is made of conjunctive tissue set in parallel layers and vessels with macrolipophagic degeneration. Microscopic investigation of retina reveals glial hyperplasia zones in the neighbourhood of the vitreous body. In the present paper the authors show the persistence of the primordial vitreous body in the left eye and bilateral dislocation of the crystalline, revealing multiple ocular malformations.

  9. [An intractable gastric cancer showing an extremely effective response to immunochemotherapy].

    PubMed

    Takashima, S; Komaki, H; Yokota, H; Kiriyama, M; Kinami, Y

    1988-07-01

    Reported herein is the case of a terminal patient with advanced gastric cancer who was shown an extremely effective response to immunochemotherapy. The patient, a 62-year-old female, was determined as having a gastric cancer, Borr. type 2, originating in the pyloric antrum. The tumor was found to be H3P3S2N2 (stage IV), and its histology revealed a mucus-producing papillary adeno-carcinoma, ss gamma, n(+), ly2, and V1. Thus the patient underwent a distal gastrectomy, and was given an operative administration of MMC, followed by postoperative immunochemotherapy with FT 207 and OK 432. Consequently, no ascites were noticed throughout the recuperative course, and repeated CT scannings of the hepatic metastatic lesions, revealed a remarkable regression. Two years after this operation, she resumed normal daily life. Further, her preoperatively elevated tumor markers have returned to normal.

  10. 78 FR 71643 - Certain Opaque Polymers; Notice of Commission Decision Amending the Complaint and Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-883] Certain Opaque Polymers; Notice of Commission Decision Amending the Complaint and Notice of Investigation AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International Trade Commission has...

  11. 78 FR 69172 - Defense Trade Advisory Group; Notice of Cancellation of Open Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-18

    ... DEPARTMENT OF STATE [Public Notice 8525] Defense Trade Advisory Group; Notice of Cancellation of Open Meeting AGENCY: Department of State. ACTION: Notice of Cancellation of meeting. SUMMARY: The notice references Public Notice 8515 published in the November 12, 2013 Federal Register, announcing the...

  12. 16 CFR 16.9 - Notice of meetings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... COMMITTEE MANAGEMENT § 16.9 Notice of meetings. (a) Notice of each advisory committee meeting, whether open... meeting date. Such notice shall include the exact name of the advisory committee as chartered; the time... this section, other forms of notice such as press releases and notices in professional journals may be...

  13. 76 FR 55740 - Proposed Collection; Comment Request for Notice 99-43

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-08

    ... Notice 99-43 AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request for comments... Notice 99-43, Nonrecognition Exchanges under Section 897. DATES: Written comments should be received on... Number: Notice 99-43. Abstract: Notice 99-43 announces modification of the current rules under Temporary...

  14. 18 CFR 157.9 - Notice of application and notice of schedule for environmental review.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... and notice of schedule for environmental review. 157.9 Section 157.9 Conservation of Power and Water... Amended, Concerning Any Operation, Sales, Service, Construction, Extension, Acquisition or Abandonment § 157.9 Notice of application and notice of schedule for environmental review. (a) Notice of each...

  15. Aegilops tauschii Accessions with Geographically Diverse Origin Show Differences in Chromosome Organization and Polymorphism of Molecular Markers Linked to Leaf Rust and Powdery Mildew Resistance Genes.

    PubMed

    Majka, Maciej; Kwiatek, Michał T; Majka, Joanna; Wiśniewska, Halina

    2017-01-01

    Aegilops tauschii (2n = 2x = 14) is a diploid wild species which is reported as a donor of the D-genome of cultivated bread wheat. The main goal of this study was to examine the differences and similarities in chromosomes organization among accessions of Ae. tauschii with geographically diversed origin, which is believed as a potential source of genes, especially determining resistance to fungal diseases (i.e., leaf rust and powdery mildew) for breeding of cereals. We established and compared the fluorescence in situ hybridization patterns of 21 accessions of Ae. tauschii using various repetitive sequences mainly from the BAC library of wheat cultivar Chinese Spring. Results obtained for Ae. tauschii chromosomes revealed many similarities between analyzed accessions, however, some hybridization patterns were specific for accessions, which become from cognate regions of the World. The most noticeable differences were observed for accessions from China which were characterized by presence of distinct signals of pTa-535 in the interstitial region of chromosome 3D, less intensity of pTa-86 signals in chromosome 2D, as well as lack of additional signals of pTa-86 in chromosomes 1D, 5D, or 6D. Ae. tauschii of Chinese origin appeared homogeneous and separate from landraces that originated in western Asia. Ae. tauschii chromosomes showed similar hybridization patterns to wheat D-genome chromosomes, but some differences were also observed among both species. What is more, we identified reciprocal translocation between short arm of chromosome 1D and long arm of chromosome 7D in accession with Iranian origin. High polymorphism between analyzed accessions and extensive allelic variation were revealed using molecular markers associated with resistance genes. Majority of the markers localized in chromosomes 1D and 2D showed the diversity of banding patterns between accessions. Obtained results imply, that there is a moderate or high level of polymorphism in the genome of Ae . tauschii determined by a geographical origin, which we proved by cytogenetic and molecular markers analysis. Therefore, selected accessions might constitute an accessible source of variation for improvement of Triticeae species like wheat and triticale.

  16. Role of electronic excitation in the amorphization of Ge-Sb-Te alloys.

    PubMed

    Li, Xian-Bin; Liu, X Q; Liu, Xin; Han, Dong; Zhang, Z; Han, X D; Sun, Hong-Bo; Zhang, S B

    2011-07-01

    First-principles molecular dynamics simulation reveals the effects of electronic excitation in the amorphization of Ge-Sb-Te. The excitation makes the phase change an element-selective process, lowers the critical amorphization temperature considerably, for example, to below 700 K at a 9% excitation, and reduces the atomic diffusion coefficient with respect to that of melt by at least 1 order of magnitude. Noticeably, the resulting structure has fewer wrong bonds and significantly increased phase-change reversibility. Our results point to a new direction in manipulating ultrafast phase-change processes with improved controllability.

  17. Breast abscess as a complication of human brucellosis.

    PubMed

    Gurleyik, Emin

    2006-01-01

    Breast abscess caused by human brucellosis is extremely rare. A 46-year-old woman received the diagnosis of brucellosis with positive serologic tests. Two weeks after the onset of symptoms, the case was complicated by vertebral (L5-S1) abscess which was treated by surgical drainage. One month after the diagnosis of brucellosis, the patient noticed a mass in her left breast. Breast palpation revealed a painless, mobile, round mass that was hypoechoic on ultrasound imaging. Purulent material was obtained by needle aspiration. Besides treatment of the breast abscess by needle aspiration, brucellosis was successfully controlled by prolonged antimicrobial treatment.

  18. Reduction of nitrogen oxides (NOx) by superalkalis

    NASA Astrophysics Data System (ADS)

    Srivastava, Ambrish Kumar

    2018-03-01

    NOx are major air pollutants, having negative impact on environment and consequently, human health. We propose here the single-electron reduction of NOx (x = 1, 2) using superalkalis. We study the interaction of NOx with FLi2, OLi3 and NLi4 superalkalis using density functional and single-point CCSD(T) calculations, which lead to stable superalkali-NOx ionic complexes with negatively charged NOx. This clearly reveals that the NOx can successfully be reduced to NOx- anion due to electron transfer from superalkalis. It has been also noticed that the size of superalkalis plays a crucial in the single-electron reduction of NOx.

  19. Sexually transmitted diseases in the history of Uganda.

    PubMed

    Lyons, M

    1994-04-01

    First noticed in Uganda in 1863 by a European explorer, sexually transmitted diseases (STDs) were cited as a major cause of morbidity and mortality throughout this century. In 1908 the venereal diseases campaign was launched marking the real introduction of western medicine. By the mid-1920s, the campaign was combined with the medical service but throughout the colonial period (1901-1962) venereal diseases were considered intractable. A 1991 survey revealed alarming incidence rates and in light of the importance of STDs as a co-factor in the transmission of HIV, it is of paramount importance to implement more effective control measures.

  20. 12 CFR 717.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CREDIT REPORTING Affiliate Marketing § 717.26 Delivery of opt-out notices. (a) In general. The opt-out... the notice; or (4) Posts the notice on the Internet Web site at which the consumer obtained a product... notice; or (3) Posts the notice on an Internet Web site without requiring the consumer to acknowledge...

  1. 12 CFR 222.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SYSTEM FAIR CREDIT REPORTING (REGULATION V) Affiliate Marketing § 222.26 Delivery of opt-out notices. (a... the affiliate providing the notice; or (4) Posts the notice on the Internet Web site at which the... affiliate providing the notice; or (3) Posts the notice on an Internet Web site without requiring the...

  2. 12 CFR 334.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... POLICY FAIR CREDIT REPORTING Affiliate Marketing § 334.26 Delivery of opt-out notices. (a) In general... the notice; or (4) Posts the notice on the Internet Web site at which the consumer obtained a product... notice; or (3) Posts the notice on an Internet Web site without requiring the consumer to acknowledge...

  3. 78 FR 22876 - Rodenticides; Notice of Intent To Cancel Registrations of, and Notice of Denial of Applications...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-17

    ... ENVIRONMENTAL PROTECTION AGENCY [FIFRA Docket No. 661; FRL-9804-2] Rodenticides; Notice of Intent To Cancel Registrations of, and Notice of Denial of Applications for, Certain Rodenticide Bait... to the Notice of Intent to Cancel Registration of, and Notice of Denial of Application for, Certain...

  4. 78 FR 16046 - Proposed Collection; Comment Request for Notice 2010-6

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-13

    ... Notice 2010-6 AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request for comments... Notice 2010-6, Relief and Guidance on Corrections of Certain Failures of a Nonqualified Deferred... Compensation Plan to Comply with Section 409A(a). OMB Number: 1545-2164. Notice Number: Notice 2010-6 Abstract...

  5. 47 CFR 51.329 - Notice of network changes: Methods for providing notice.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Notice of network changes: Methods for... Carriers § 51.329 Notice of network changes: Methods for providing notice. (a) In providing the required notice to the public of network changes, an incumbent LEC may use one of the following methods: (1...

  6. 47 CFR 51.329 - Notice of network changes: Methods for providing notice.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Notice of network changes: Methods for... Carriers § 51.329 Notice of network changes: Methods for providing notice. (a) In providing the required notice to the public of network changes, an incumbent LEC may use one of the following methods: (1...

  7. 12 CFR 571.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Affiliate Marketing § 571.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be... consumer may reasonably be expected to receive actual notice if the affiliate providing the notice: (1... agreed to receive electronic disclosures by e-mail from the affiliate providing the notice; or (4) Posts...

  8. 12 CFR 41.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Affiliate Marketing § 41.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be provided... consumer may reasonably be expected to receive actual notice if the affiliate providing the notice: (1... agreed to receive electronic disclosures by e-mail from the affiliate providing the notice; or (4) Posts...

  9. 12 CFR 222.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... SYSTEM (CONTINUED) FAIR CREDIT REPORTING (REGULATION V) Affiliate Marketing § 222.26 Delivery of opt-out... actual notice if the affiliate providing the notice: (1) Hand-delivers a printed copy of the notice to...-mail from the affiliate providing the notice; or (4) Posts the notice on the Internet Web site at which...

  10. 12 CFR 1022.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) Affiliate Marketing § 1022.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be... consumer may reasonably be expected to receive actual notice if the affiliate providing the notice: (1... agreed to receive electronic disclosures by email from the affiliate providing the notice; or (4) Posts...

  11. 12 CFR 41.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Affiliate Marketing § 41.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be provided... consumer may reasonably be expected to receive actual notice if the affiliate providing the notice: (1... agreed to receive electronic disclosures by e-mail from the affiliate providing the notice; or (4) Posts...

  12. 12 CFR 41.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Affiliate Marketing § 41.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be provided... consumer may reasonably be expected to receive actual notice if the affiliate providing the notice: (1... agreed to receive electronic disclosures by e-mail from the affiliate providing the notice; or (4) Posts...

  13. 12 CFR 1022.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) Affiliate Marketing § 1022.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be... consumer may reasonably be expected to receive actual notice if the affiliate providing the notice: (1... agreed to receive electronic disclosures by email from the affiliate providing the notice; or (4) Posts...

  14. 12 CFR 1022.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) Affiliate Marketing § 1022.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be... consumer may reasonably be expected to receive actual notice if the affiliate providing the notice: (1... agreed to receive electronic disclosures by email from the affiliate providing the notice; or (4) Posts...

  15. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt out...) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple...

  16. 12 CFR 222.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... SYSTEM (CONTINUED) FAIR CREDIT REPORTING (REGULATION V) Affiliate Marketing § 222.26 Delivery of opt-out... actual notice if the affiliate providing the notice: (1) Hand-delivers a printed copy of the notice to...-mail from the affiliate providing the notice; or (4) Posts the notice on the Internet Web site at which...

  17. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt out...) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple...

  18. 12 CFR 571.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Affiliate Marketing § 571.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be... consumer may reasonably be expected to receive actual notice if the affiliate providing the notice: (1... agreed to receive electronic disclosures by e-mail from the affiliate providing the notice; or (4) Posts...

  19. 12 CFR 571.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Affiliate Marketing § 571.26 Delivery of opt-out notices. (a) In general. The opt-out notice must be... consumer may reasonably be expected to receive actual notice if the affiliate providing the notice: (1... agreed to receive electronic disclosures by e-mail from the affiliate providing the notice; or (4) Posts...

  20. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt out...) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple...

  1. 12 CFR 332.8 - Revised privacy notices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Revised privacy notices. 332.8 Section 332.8... PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 332.8 Revised privacy notices. (a... described in your prior notice. (c) Delivery. When you are required to deliver a revised privacy notice by...

  2. 17 CFR 160.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Delivering privacy and opt out... PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 160.9 Delivering privacy and opt out notices. (a) How to provide notices. You must provide any privacy notices and opt out notices...

  3. 12 CFR 332.8 - Revised privacy notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 5 2012-01-01 2012-01-01 false Revised privacy notices. 332.8 Section 332.8... PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 332.8 Revised privacy notices. (a... described in your prior notice. (c) Delivery. When you are required to deliver a revised privacy notice by...

  4. 16 CFR 313.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Delivering privacy and opt out notices. 313... CONGRESS PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 313.9 Delivering privacy and opt out notices. (a) How to provide notices. You must provide any privacy notices and opt out...

  5. 12 CFR 332.8 - Revised privacy notices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Revised privacy notices. 332.8 Section 332.8... PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 332.8 Revised privacy notices. (a... described in your prior notice. (c) Delivery. When you are required to deliver a revised privacy notice by...

  6. 12 CFR 332.8 - Revised privacy notices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Revised privacy notices. 332.8 Section 332.8... PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 332.8 Revised privacy notices. (a... described in your prior notice. (c) Delivery. When you are required to deliver a revised privacy notice by...

  7. 12 CFR 332.8 - Revised privacy notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Revised privacy notices. 332.8 Section 332.8... PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 332.8 Revised privacy notices. (a... described in your prior notice. (c) Delivery. When you are required to deliver a revised privacy notice by...

  8. 40 CFR 720.75 - Notice review period.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Notice review period. 720.75 Section... ACT PREMANUFACTURE NOTIFICATION Disposition of Notices § 720.75 Notice review period. (a) Length of notice review period. The notice review period specified in section 5(a) of the Act runs for 90 days from...

  9. Reported exposure to E-cigarette advertising and promotion in different regulatory environments: Findings from the International Tobacco Control Four Country (ITC-4C) Survey.

    PubMed

    Wadsworth, E; McNeill, A; Li, L; Hammond, D; Thrasher, J F; Yong, H-H; Cummings, K M; Fong, G T; Hitchman, S C

    2018-07-01

    Electronic cigarette (e-cigarette) advertising regulations differ across countries. This study examines how differences in e-cigarette advertising regulations influence exposure to e-cigarette advertising, and perceptions about what participants had seen and read about e-cigarettes. Data come from the ITC Four Country Survey (Canada [CA], United States [US], Australia [AU] and United Kingdom [UK]) carried out between August 2013 and March 2015 (n = 3460). In 2014, AU and CA had laws prohibiting the retail sale of e-cigarettes containing nicotine while the US and UK had no restrictions, although a voluntary agreement restricting advertising in the UK was introduced during fieldwork. Smokers and ex-smokers were asked whether in the last six months they had noticed e-cigarettes advertisements and received free samples/special offers (promotion), and about their perceptions (positive or otherwise) of what they had seen or read about e-cigarettes. Data were analyzed in 2017. US and UK participants were more likely to report that they had noticed e-cigarette advertisements and received promotions compared to CA or AU participants. For TV and radio advertisements, reported exposure was higher in US compared to UK. For all types of advertisements, reported exposure was higher in CA than AU. Overall, nearly half of AU (44.0%) and UK (47.8%) participants perceived everything they had seen and read about e-cigarettes to be positive, with no significant differences between AU and UK. Participants in countries with permissive e-cigarette advertising restrictions and less restrictive e-cigarette regulations were more likely to notice advertisements than participants in countries with more restrictive e-cigarette regulations. Copyright © 2018 Elsevier Inc. All rights reserved.

  10. Ereptiospiration.

    PubMed

    Woolley, Christine; Garcia, Antonio A; Santello, Marco

    2017-04-12

    Pure coconut oil, lanolin, and acetaminophen were vaporized at rates of 1-50 mg/min, using a porous network exhibiting a temperature gradient from 5000 to 5500 K/mm, without incurring noticeable chemical changes due to combustion, oxidation, or other thermally-induced chemical structural changes. The newly coined term "ereptiospiration" is used here to describe this combination of thermal transpiration at high temperature gradients since the process can force the creation of thermal aerosols by rapid heating in a localized zone. Experimental data were generated for these materials using two different supports for metering the materials to the battery powered coil: namely, a stainless steel fiber bundle and a 3-D printed steel cartridge. Heating coconut oil, lanolin, or acetaminophen in a beaker to lower temperatures than those achieved at the surface of the coil showed noticeable and rapid degradation in the samples, while visual and olfactory observations for ereptiospiration showed no noticeable degradation in lanolin and coconut oil while HPLC chromatograms along with visual observation confirm that within the limit of detection, acetaminophen remains chemically unaltered by ereptiospiration.

  11. 78 FR 76896 - Proposed Collection; Comment Request for Notices 2010-83 and 2011-3

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-19

    ... Notices 2010-83 and 2011-3 AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request... and Notice 2011-3, Special Rules Relating to Funding Relief for Single-Employer Pension Plans under...- Employer Pension Plans under PRA 2010. OMB Number: 1545-2196. Form Number: Notice 2010-83 and Notice 2011-3...

  12. 76 FR 45312 - Notice of Intent To Prepare an Environmental Assessment, Notice of Public Meetings, and Notice To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-28

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Intent To Prepare an Environmental Assessment, Notice of Public Meetings, and Notice To Request Public Scoping Comments for the Air Tour Management Plan Program at Golden Gate National Recreation Area, San Francisco Maritime National Historical Park and Point Reyes National...

  13. 12 CFR 205.8 - Change in terms notice; error resolution notice.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Change in terms notice; error resolution notice. 205.8 Section 205.8 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM ELECTRONIC FUND TRANSFERS (REGULATION E) § 205.8 Change in terms notice; error resolution notice...

  14. 16 CFR 680.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REPORTING ACT AFFILIATE MARKETING § 680.23 Contents of opt-out notice; consolidated and equivalent notices... must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC,” then the...

  15. 17 CFR 248.123 - Contents of opt out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... EXCHANGE COMMISSION (CONTINUED) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing § 248.123 Contents of opt out notice; consolidated and equivalent notices. (a) Contents of opt out...) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple...

  16. 16 CFR 680.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... REPORTING ACT AFFILIATE MARKETING § 680.23 Contents of opt-out notice; consolidated and equivalent notices... must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC,” then the...

  17. 16 CFR 680.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REPORTING ACT AFFILIATE MARKETING § 680.23 Contents of opt-out notice; consolidated and equivalent notices... must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC,” then the...

  18. 16 CFR 680.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... REPORTING ACT AFFILIATE MARKETING § 680.23 Contents of opt-out notice; consolidated and equivalent notices... must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC,” then the...

  19. 12 CFR 332.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Delivering privacy and opt out notices. 332.9... GENERAL POLICY PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 332.9 Delivering privacy and opt out notices. (a) How to provide notices. You must provide any privacy notices and opt out...

  20. 12 CFR 216.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 2 2012-01-01 2012-01-01 false Delivering privacy and opt out notices. 216.9... PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) Privacy and Opt Out Notices § 216.9 Delivering privacy and opt out notices. (a) How to provide notices. You must provide any privacy notices and opt out...

  1. 12 CFR 205.8 - Change in terms notice; error resolution notice.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Change in terms notice; error resolution notice. 205.8 Section 205.8 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM ELECTRONIC FUND TRANSFERS (REGULATION E) § 205.8 Change in terms notice; error resolution notice...

  2. 47 CFR 51.333 - Notice of network changes: Short term notice, objections thereto and objections to retirement of...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false Notice of network changes: Short term notice... Additional Obligations of Incumbent Local Exchange Carriers § 51.333 Notice of network changes: Short term... changes, the public notice or certification that it files with the Commission must include a certificate...

  3. Effects of salting treatment on the physicochemical properties, textural properties, and microstructures of duck eggs.

    PubMed

    Xu, Lilan; Zhao, Yan; Xu, Mingsheng; Yao, Yao; Nie, Xuliang; Du, Huaying; Tu, Yong-Gang

    2017-01-01

    In order to illuminate the forming process of salted egg, the effects of the brine solution with different salt concentrations on the physicochemical properties, textural properties, and microstructures of duck eggs were evaluated using conventional physicochemical property determination methods. The results showed that the moisture contents of both the raw and cooked egg whites and egg yolks, the springiness of the raw egg yolks and cooked egg whites exhibited a decreasing trend with the increase in the salting time and salt concentration. The salt content, oil exudation and the hardness of the raw egg yolks showed a constantly increasing trend. Viscosity of the raw egg whites showed an overall trend in which it first deceased and then increased and decreased again, which was similar to the trend of the hardness of the cooked egg whites and egg yolks. As the salting proceeded, the pH value of the raw and cooked egg whites declined remarkably and then declined slowly, whereas the pH of the raw and cooked egg yolks did not show any noticeable changes. The effect of salting on the pH value varied significantly with the salt concentration in the brine solution. Scanning electron microscopy (SEM) revealed that salted yolks consist of spherical granules and embedded flattened porosities. It was concluded that the treatment of salt induces solidification of yolk, accompanied with higher oil exudation and the development of a gritty texture. Different salt concentrations show certain differences.

  4. Effects of salting treatment on the physicochemical properties, textural properties, and microstructures of duck eggs

    PubMed Central

    Xu, Lilan; Zhao, Yan; Xu, Mingsheng; Yao, Yao; Nie, Xuliang; Du, Huaying

    2017-01-01

    In order to illuminate the forming process of salted egg, the effects of the brine solution with different salt concentrations on the physicochemical properties, textural properties, and microstructures of duck eggs were evaluated using conventional physicochemical property determination methods. The results showed that the moisture contents of both the raw and cooked egg whites and egg yolks, the springiness of the raw egg yolks and cooked egg whites exhibited a decreasing trend with the increase in the salting time and salt concentration. The salt content, oil exudation and the hardness of the raw egg yolks showed a constantly increasing trend. Viscosity of the raw egg whites showed an overall trend in which it first deceased and then increased and decreased again, which was similar to the trend of the hardness of the cooked egg whites and egg yolks. As the salting proceeded, the pH value of the raw and cooked egg whites declined remarkably and then declined slowly, whereas the pH of the raw and cooked egg yolks did not show any noticeable changes. The effect of salting on the pH value varied significantly with the salt concentration in the brine solution. Scanning electron microscopy (SEM) revealed that salted yolks consist of spherical granules and embedded flattened porosities. It was concluded that the treatment of salt induces solidification of yolk, accompanied with higher oil exudation and the development of a gritty texture. Different salt concentrations show certain differences. PMID:28797071

  5. Chemical Composition of Selected Commercial Herbal Remedies in Relation to Geographical Origin and Inter-Species Diversity.

    PubMed

    Konieczynski, Pawel; Viapiana, Agnieszka; Lysiuk, Roman; Wesolowski, Marek

    2018-03-01

    Infusions prepared from medicinal herbs that are rich in flavonoids are very popular herbal remedies in societies of Eastern Europe. Therefore, the content of essential elements together with total flavonoids was analyzed in 65 commercially available samples of herbal drugs originating from Ukraine, Romania, and Belarus. The results showed that metallic elements (in mg kg -1 d.w.) have occurred in the following order: Fe > Mn > Zn > Cu, both for total and water-extractable species. Total flavonoids were determined in the range from 10.0 to 191.8 mg g -1 d.w. Several significant correlations have been found between the analytes, especially among water-extractable Fe with other metals, and total flavonoids and Fe, Zn, and Mn. Analysis of variance has revealed significant differences among studied samples due to their origin from different countries, especially between Belarussian samples and others. Differences owing to belonging to various plant species were also found, as it was noticed in the case of Polygoni aviculare herba in comparison with other botanical plant species. Moreover, multivariate statistical techniques, such as cluster analysis (CA) and principal component analysis (PCA) were used to gather herbal drugs based on similarity of chemical composition. CA grouped the samples into clusters with similar level of elements and total flavonoid contents, and PCA has indicated Hyperici herba, Tiliae flores, and Crataegi fructus as herbal remedies with close concentration of studied elements and flavonoids.

  6. Simulated aging of lubricant oils by chemometric treatment of infrared spectra: potential antioxidant properties of sulfur structures.

    PubMed

    Amat, Sandrine; Braham, Zeineb; Le Dréau, Yveline; Kister, Jacky; Dupuy, Nathalie

    2013-03-30

    Lubricant oils are complex mixtures of base oils and additives. The evolution of their performance over time strongly depends on its resistance to thermal oxidation. Sulfur compounds revealed interesting antioxidant properties. This study presents a method to evaluate the lubricant oil oxidation. Two samples, a synthetic and a paraffinic base oils, were tested pure and supplemented with seven different sulfur compounds. An aging cell adapted to a Fourier Transform InfraRed (FT-IR) spectrometer allows the continuous and direct analysis of the oxidative aging of base oils. Two approaches were applied to study the oxidation/anti-oxidation phenomena. The first one leads to define a new oxidative spectroscopic index based on a reduced spectral range where the modifications have been noticed (from 3050 to 2750 cm(-1)). The second method is based on chemometric treatments of whole spectra (from 4000 to 400 cm(-1)) to extract underlying information. A SIMPLe-to-use Interactive Self Modeling Analysis (SIMPLISMA) method has been used to identify more precisely the chemical species produced or degraded during the thermal treatment and to follow their evolution. Pure spectra of different species present in oil were obtained without prior information of their existence. The interest of this tool is to supply relative quantitative information reflecting evolution of the relative abundance of the different products over thermal aging. Results obtained by these two ways have been compared to estimate their concordance. Copyright © 2013 Elsevier B.V. All rights reserved.

  7. Measurements With a Split-Fiber Probe in Complex Unsteady Flows

    NASA Technical Reports Server (NTRS)

    Lepicovsky, Jan

    2004-01-01

    A split-fiber probe was used to acquire unsteady data in a research compressor. A calibration method was devised for a split-fiber probe, and a new algorithm was developed to decompose split-fiber probe signals into velocity magnitude and direction. The algorithm is based on the minimum value of a merit function that is built over the entire range of flow velocities for which the probe was calibrated. The split-fiber probe performance and signal decomposition was first verified in a free-jet facility by comparing the data from three thermo-anemometric probes, namely a single-wire, a single-fiber, and the split-fiber probe. All three probes performed extremely well as far as the velocity magnitude was concerned. However, there are differences in the peak values of measured velocity unsteadiness in the jet shear layer. The single-wire probe indicates the highest unsteadiness level, followed closely by the split-fiber probe. The single-fiber probe indicates a noticeably lower level of velocity unsteadiness. Experiments in the NASA Low Speed Axial Compressor facility revealed similar results. The mean velocities agreed well, and differences in the velocity unsteadiness are similar to the case of a free jet. A reason for these discrepancies is in the different frequency response characteristics of probes used. It follows that the single-fiber probe has the slowest frequency response. In summary, the split-fiber probe worked reliably during the entire program. The acquired data averaged in time followed closely data acquired by conventional pneumatic probes.

  8. Shelf-life of bioprosthetic heart valves: a structural and mechanical study.

    PubMed

    Julien, M; Létouneau, D R; Marois, Y; Cardou, A; King, M W; Guidoin, R; Chachra, D; Lee, J M

    1997-04-01

    This study was undertaken to evaluate the influence of storage conditions on the shelf-life of porcine bioprosthetic valves. Fifty-five unimplanted porcine bioprostheses have been evaluated. The valves were stored in 0.5% buffered glutaraldehyde solution for different periods of time (7, 23 and 32 months). Twenty-eight valves were refrigerated while the remaining valves were stored at room temperature. The pH of the glutaraldehyde solution at room temperature decreased with time of storage, while that kept in the refrigerator remained stable over the course of the study. Macroscopic observations showed that the valve tissues kept at room temperature, especially for the periods of 23 and 32 months, became darker and more yellow in colour, whereas the refrigerated specimens exhibited no such changes in appearance. Scanning electron microscopy analysis revealed no noticeable differences on the surfaces of the leaflets stored under different conditions. Mechanical tests, including stress-strain response, stress relaxation and fracture behaviour, were carried out. Analysis of variance showed that the storage temperature, but not the length of storage, had a significant effect on some mechanical properties. The stress relaxation at 1000 s (P = 0.05), the ultimate tensile strength (P = 0.01) and the strain at fracture (P = 0.04) were all higher after storage at room temperature compared to the results after refrigeration. No statistically significant changes in the denaturation temperature of the collagen were observed between the different storage conditions. In conclusion, the storage temperature appears to have some influence on the bioprosthetic tissue. The bioprostheses stored under ambient conditions experience changes which may influence their longterm in vivo performance.

  9. Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation.

    PubMed

    Arnardottir, Erna S; Nikonova, Elena V; Shockley, Keith R; Podtelezhnikov, Alexei A; Anafi, Ron C; Tanis, Keith Q; Maislin, Greg; Stone, David J; Renger, John J; Winrow, Christopher J; Pack, Allan I

    2014-10-01

    To address whether changes in gene expression in blood cells with sleep loss are different in individuals resistant and sensitive to sleep deprivation. Blood draws every 4 h during a 3-day study: 24-h normal baseline, 38 h of continuous wakefulness and subsequent recovery sleep, for a total of 19 time-points per subject, with every 2-h psychomotor vigilance task (PVT) assessment when awake. Sleep laboratory. Fourteen subjects who were previously identified as behaviorally resistant (n = 7) or sensitive (n = 7) to sleep deprivation by PVT. Thirty-eight hours of continuous wakefulness. We found 4,481 unique genes with a significant 24-h diurnal rhythm during a normal sleep-wake cycle in blood (false discovery rate [FDR] < 5%). Biological pathways were enriched for biosynthetic processes during sleep. After accounting for circadian effects, two genes (SREBF1 and CPT1A, both involved in lipid metabolism) exhibited small, but significant, linear changes in expression with the duration of sleep deprivation (FDR < 5%). The main change with sleep deprivation was a reduction in the amplitude of the diurnal rhythm of expression of normally cycling probe sets. This reduction was noticeably higher in behaviorally resistant subjects than sensitive subjects, at any given P value. Furthermore, blood cell type enrichment analysis showed that the expression pattern difference between sensitive and resistant subjects is mainly found in cells of myeloid origin, such as monocytes. Individual differences in behavioral effects of sleep deprivation are associated with differences in diurnal amplitude of gene expression for genes that show circadian rhythmicity. © 2014 Associated Professional Sleep Societies, LLC.

  10. A review of the physiological and histological effects of laser osteotomy.

    PubMed

    Rajitha Gunaratne, G D; Khan, Riaz; Fick, Daniel; Robertson, Brett; Dahotre, Narendra; Ironside, Charlie

    2017-01-01

    Osteotomy is the surgical cutting of bone. Some obstacles to laser osteotomy have been melting, carbonisation and subsequent delayed healing. New cooled scanning techniques have resulted in effective bone cuts without the strong thermal side effects, which were observed by inappropriate irradiation techniques with continuous wave and long pulsed lasers. With these new techniques, osteotomy gaps histologically healed with new bone formation without any noticeable or minimum thermal damage. No significant cellular differences in bone healing between laser and mechanical osteotomies were noticed. Some studies even suggest that the healing rate may be enhanced following laser osteotomy compared to conventional mechanical osteotomy. Additional research is necessary to evaluate different laser types with appropriate laser setting variables to increase ablation rates, with control of depth, change in bone type and damage to adjacent soft tissue. Laser osteotomy has the potential to become incorporated into the armamentarium of bone surgery.

  11. [Peculiarities of visual perception of dentition and smile aesthetic parameters].

    PubMed

    Riakhovskiĭ, A N; Usanova, E V

    2007-01-01

    As the result of the studies it was determined in which limits the dentition central line displacement from the face middle line and the change of smile line tilt angle become noticeable for visual perception. And also how much visual perception of the dentition aesthetic parameters were differed in doctors with different experience, dental technicians and patients.

  12. 76 FR 71102 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ... floor brokerage business has a different business model as compared to members conducting an electronic business.\\17\\ The Exchange believes that it is reasonable to pay a rebate for only eQCC Orders in an... QCC Orders is reasonable because of the different business models, described herein, that apply to a...

  13. 26 CFR 400.1-1 - Refiling of notice of tax lien.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... notice of lien is refiled in the office in which the prior notice of lien (including a refiled notice... his change in residence to N State more than 89 days prior to the date refiling of the notice of lien... to R State was the most recent notice received more than 89 days prior to the date refiling in O...

  14. 47 CFR 51.333 - Notice of network changes: Short term notice, objections thereto and objections to retirement of...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 3 2011-10-01 2011-10-01 false Notice of network changes: Short term notice... Additional Obligations of Incumbent Local Exchange Carriers § 51.333 Notice of network changes: Short term...) Certificate of service. If an incumbent LEC wishes to provide less than six months notice of planned network...

  15. 47 CFR 51.333 - Notice of network changes: Short term notice, objections thereto and objections to retirement of...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Notice of network changes: Short term notice... Additional Obligations of Incumbent Local Exchange Carriers § 51.333 Notice of network changes: Short term...) Certificate of service. If an incumbent LEC wishes to provide less than six months notice of planned network...

  16. Large differences in proportions of harmful and benign amino acid substitutions between proteins and diseases.

    PubMed

    Schaafsma, Gerard C P; Vihinen, Mauno

    2017-07-01

    Genes and proteins are known to have differences in their sensitivity to alterations. Despite numerous sequencing studies, proportions of harmful and harmless substitutions are not known for proteins and groups of proteins. To address this question, we predicted the outcome for all possible single amino acid substitutions (AASs) in nine representative protein groups by using the PON-P2 method. The effects on 996 proteins were studied and vast differences were noticed. Proteins in the cancer group harbor the largest proportion of harmful variants (42.1%), whereas the non-disease group of proteins not known to have a disease association and not involved in the housekeeping functions had the lowest number of harmful variants (4.2%). Differences in the proportions of the harmful and benign variants are wide within each group, but they still show clear differences between the groups. Frequently appearing protein domains show a wide spectrum of variant frequencies, whereas no major protein structural class-specific differences were noticed. AAS types in the original and variant residues showed distinctive patterns, which are shared by all the protein groups. The observations are relevant for understanding genetic bases of diseases, variation interpretation, and for the development of methods for that purpose. © 2017 Wiley Periodicals, Inc.

  17. 12 CFR 573.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 6 2013-01-01 2012-01-01 true Form of opt out notice to consumers; opt out... PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 573.7 Form of opt out notice to consumers; opt out methods. (a)(1) Form of opt out notice. If you are required to provide an opt out notice...

  18. 17 CFR 248.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Form of opt out notice to... Safeguarding Personal Information Privacy and Opt Out Notices § 248.7 Form of opt out notice to consumers; opt out methods. (a)(1) Form of opt out notice. If you are required to provide an opt out notice under...

  19. 12 CFR 573.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 6 2014-01-01 2012-01-01 true Form of opt out notice to consumers; opt out... PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 573.7 Form of opt out notice to consumers; opt out methods. (a)(1) Form of opt out notice. If you are required to provide an opt out notice...

  20. 17 CFR 248.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Form of opt out notice to... Safeguarding Personal Information Privacy and Opt Out Notices § 248.7 Form of opt out notice to consumers; opt out methods. (a)(1) Form of opt out notice. If you are required to provide an opt out notice under...

  1. 12 CFR 573.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 6 2012-01-01 2012-01-01 false Form of opt out notice to consumers; opt out... PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 573.7 Form of opt out notice to consumers; opt out methods. (a)(1) Form of opt out notice. If you are required to provide an opt out notice...

  2. 12 CFR 573.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Form of opt out notice to consumers; opt out... PRIVACY OF CONSUMER FINANCIAL INFORMATION Privacy and Opt Out Notices § 573.7 Form of opt out notice to consumers; opt out methods. (a)(1) Form of opt out notice. If you are required to provide an opt out notice...

  3. 17 CFR 248.7 - Form of opt out notice to consumers; opt out methods.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Form of opt out notice to... Safeguarding Personal Information Privacy and Opt Out Notices § 248.7 Form of opt out notice to consumers; opt out methods. (a)(1) Form of opt out notice. If you are required to provide an opt out notice under...

  4. 30 CFR 285.216 - What information will MMS publish in the Proposed Sale Notice and Final Sale Notice?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What information will MMS publish in the... information will MMS publish in the Proposed Sale Notice and Final Sale Notice? For each competitive lease sale, MMS will publish a Proposed Sale Notice and a Final Sale Notice in the Federal Register. In the...

  5. 77 FR 43355 - Notice of Availability of the Proposed Notice of Sale for Outer Continental Shelf (OCS) Oil and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ... Proposed Notice of Sale for Outer Continental Shelf (OCS) Oil and Gas Lease Sale 229 in the Western...: Notice of Availability of the Proposed Notice of Sale for Proposed Sale 229. SUMMARY: BOEM announces the availability of the Proposed Notice of Sale (NOS) for proposed Sale 229 in the WPA. This sale will be the first...

  6. 77 FR 4360 - Notice of Availability of the Proposed Notice of Sale for Outer Continental Shelf (OCS) Oil and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-27

    ... Proposed Notice of Sale for Outer Continental Shelf (OCS) Oil and Gas Lease Sale 216/222 in the Central...: Notice of Availability of the Proposed Notice of Sale for Proposed Sale 216/222. SUMMARY: BOEM announces the availability of the proposed Notice of Sale (NOS) for proposed Sale 216/222 in the CPA. This...

  7. 75 FR 28278 - Notice of amendment to Notice of Realty Action: Competitive Online Auction of Public Lands in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-20

    .... ACTION: Notice of amendment. SUMMARY: This notice amends a Notice of Realty Action (NORA) published in... GSA Web site, https://www.auctionrp.com/ . The NORA published on September 11, 2009, is amended to...

  8. Seagrass as a potential source of natural antioxidant and anti-inflammatory agents.

    PubMed

    Yuvaraj, N; Kanmani, P; Satishkumar, R; Paari, A; Pattukumar, V; Arul, V

    2012-04-01

    Halophila spp. is a strong medicine against malaria and skin diseases and is found to be very effective in early stages of leprosy. Seagrasses are nutraceutical in nature and therefore of importance as food supplements. The antibacterial, antioxidant, and anti-inflammatory activities of Halophila ovalis R. Br. Hooke (Hydrocharitaceae) methanol extract were investigated and the chemical constituents of purified fractions were analyzed. Plant materials were collected from Pondicherry coastal line, and antimicrobial screening of crude extract, and purified fractions was carried out by the disc diffusion method and the minimum inhibitory concentration (MICs) of the purified fractions and reference antibiotics were determined by microdilution method. Antioxidant and anti-inflammatory activities were investigated in vitro. Chemical constituents of purified fractions V and VI were analyzed by gas chromatography-mass spectrometry (GC-MS), and the phytochemicals were quantitatively determined. Methanol extract inhibited the growth of Bacillus cereus at a minimum inhibitory concentration of 50 µg/mL and other Gram-negative pathogens at 75 µg/ml, except Vibrio vulnificus. Reducing power and total antioxidant level increased with increasing extract concentration. H. ovalis exhibited strong scavenging activity on 2,2-diphenyl-1-picrylhydrazyl (DPPH) and superoxide radicals at IC(50) of 0.13 and 0.65 mg/mL, respectively. Methanol extract of H. ovalis showed noticeable anti-inflammatory activity at IC(50) of 78.72 µg/mL. The GC-MS analysis of H. ovalis revealed the presence of triacylglycerols as major components in purified fractions. Quantitative analysis of phytochemicals revealed that phenols are rich in seagrass H. ovalis. These findings demonstrated that the methanol extract of H. ovalis exhibited appreciable antibacterial, noticeable antioxidant, and anti-inflammatory activities, and thus could be use as a potential source for natural health products.

  9. 77 FR 64850 - Proposed Collection; Comment Request for Notice 2009-72

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ... Notice 2009-72, Qualifying Advanced Energy Project Credit. DATES: Written comments should be received on... . SUPPLEMENTARY INFORMATION: Title: Qualifying Advanced Energy Project Credit. OMB Number: 1545-2151. Notice Number: Notice 2009-72. Abstract: This notice establishes the qualifying advanced energy project program...

  10. 76 FR 39882 - General and Plastic Surgery Devices Panel of the Medical Devices Advisory Committee; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... meeting is regarding the discussion of different innovative methodological approaches to the conduct of postmarket studies regarding silicone gel breast implants. Additionally, the panel will discuss key long-term...

  11. Identification of pavement distress in Kentucky.

    DOT National Transportation Integrated Search

    2006-04-01

    In Kentucky, the roads are comprised primarily of two types of pavement. The first being Portland Cement Concrete (PCC) a rigid pavement, and the other is Asphaltic Concrete (AC), a flexible pavement. There is a noticeable difference in their appeara...

  12. Ohio Route 50 joint sealant experiment : research implementation plan.

    DOT National Transportation Integrated Search

    2005-05-01

    Research in the state of Wisconsin over the past forty years has found no noticeable difference in : performance between jointed concrete pavement (JCP) constructed with a sealed contraction joint and : JCP constructed with a single, narrow, unsealed...

  13. 76 FR 20345 - Notice of Availability of Government-Owned Inventions; Available for Licensing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ... Case No. 98,801: APPARATUS AND METHOD FOR GRAZING ANGLE INDEPENDENT SIGNAL DETECTION// Navy Case No. 98,946: APPARATUS AND METHOD FOR COMPENSATING IMAGES FOR DIFFERENCES IN ASPECT//Navy Case No. 98,947...

  14. Attitude toward Selfie Taking and its Relation to Body Image and Narcissism in Medical Students

    PubMed Central

    Dutta, Era; Sharma, Payal; Shah, Nilesh; Bharati, Anup; Sonavane, Sushma; Desousa, Avinash

    2018-01-01

    Background: The recent and rapidly popularized social phenomenon of selfie taking has been showing an increasing trend. It is thus imperative to assess the knowledge, attitude, and perception of the groups toward this phenomenon. Selfie taking is associated with younger age groups and hence, we aimed to explore the attitudes toward selfie taking and its relation toward body image and narcissism in medical college students. Methodology: This was cross-sectional study and had two groups with Group A comprising 92 first year medical students and Group B including 103 postgraduate (PG) medical students from various specialties. They were interviewed in a single session using the scale of attitude toward selfie-taking questionnaire, Body Image Acceptance and Action Questionnaire (BIAAQ), and the narcissistic personality inventory. Scores obtained were computed using basic descriptive statistics and t-test where appropriate. Results: A strong positive favorable trend toward selfie taking was noticed among both groups (A = 56.5%, B = 45.6%). There was no difference in attitude between the two groups, or difference in the gender between those clicking their own selfies regularly within each group. BIAAQ reflected a significant difference among male subjects of the two groups with PG students was more concerned about body image (P = 0.001), whereas female subjects of both groups showed no such difference. The narcissism traits also showed a significant difference, only when males of both groups were compared again in favor of PG medical students (P = 0.022). Conclusion: This study revealed that selfie-taking is popular among medical students both in their undergraduate and PG period. Further research in diverse clinical and nonclinical populations is warranted to explore the relation between this phenomenon and body image acceptance or narcissistic traits. PMID:29403124

  15. Functional characterisation of a SNP in the ABCC11 allele - effects on axillary skin metabolism, odour generation and associated behaviours.

    PubMed

    Harker, Mark; Carvell, Ann-Marie; Marti, Vernon P J; Riazanskaia, Svetlana; Kelso, Hailey; Taylor, David; Grimshaw, Sally; Arnold, David S; Zillmer, Ruediger; Shaw, Jane; Kirk, Jayne M; Alcasid, Zee M; Gonzales-Tanon, Sheila; Chan, Gertrude P; Rosing, Egge A E; Smith, Adrian M

    2014-01-01

    A single nucleotide polymorphism (SNP), 538G→A, leading to a G180R substitution in the ABCC11 gene results in reduced concentrations of apocrine derived axillary odour precursors. Determine the axillary odour levels in the SNP ABCC11 genotype variants and to investigate if other parameters associated with odour production are affected. Axillary odour was assessed by subjective quantification and gas chromatography headspace analysis. Metabolite profiles, microbiome diversity and personal hygiene habits were also assessed. Axillary odour in the A/A homozygotes was significantly lower compared to the G/A and G/G genotypes. However, the perception-based measures still detected appreciable levels of axillary odour in the A/A subjects. Metabolomic analysis highlighted significant differences in axillary skin metabolites between A/A subjects compared to those carrying the G allele. These differences resulted in A/A subjects lacking specific volatile odourants in the axillary headspace, but all genotypes produced odoriferous short chain fatty acids. Microbiomic analysis revealed differences in the relative abundance of key bacterial genera associated with odour generation between the different genotypes. Deodorant usage indicated a high level of self awareness of axillary odour levels with A/A individuals less likely to adopt personal hygiene habits designed to eradicate/mask its presence. The SNP in the ABCC11 gene results in lower levels of axillary odour in the A/A homozygotes compared to those carrying the G allele, but A/A subjects still produce noticeable amounts of axillary odour. Differences in axillary skin metabolites, bacterial genera and personal hygiene behaviours also appear to be influenced by this SNP. Copyright © 2013. Published by Elsevier Ireland Ltd.

  16. Individual variability of venom from the European adder (Vipera berus berus) from one locality in Eastern Hungary.

    PubMed

    Malina, Tamás; Krecsák, László; Westerström, Alexander; Szemán-Nagy, Gábor; Gyémánt, Gyöngyi; M-Hamvas, Márta; Rowan, Edward G; Harvey, Alan L; Warrell, David A; Pál, Balázs; Rusznák, Zoltán; Vasas, Gábor

    2017-09-01

    We have revealed intra-population variability among venom samples from several individual European adders (Vipera berus berus) within a defined population in Eastern Hungary. Individual differences in venom pattern were noticed, both gender-specific and age-related, by one-dimensional electrophoresis. Gelatin zymography demonstrated that these individual venoms have different degradation profiles indicating varying protease activity in the specimens from adders of different ages and genders. Some specimens shared a conserved region of substrate degradation, while others had lower or extremely low protease activity. Phospholipase A 2 activity of venoms was similar but not identical. Interspecimen diversity of the venom phospholipase A 2 -spectra (based on the components' molecular masses) was detected by MALDI-TOF MS. The lethal toxicity of venoms (LD 50 ) also showed differences among individual snakes. Extracted venom samples had varying neuromuscular paralysing effect on chick biventer cervicis nerve-muscle preparations. The paralysing effect of venom was lost when calcium in the physiological salt solution was replaced by strontium; indicating that the block of twitch responses to nerve stimulation is associated with the activity of a phospholipase-dependent neurotoxin. In contrast to the studied V. b. berus venoms from different geographical regions so far, this is the first V. b. berus population discovered to have predominantly neurotoxic neuromuscular activity. The relevance of varying venom yields is also discussed. This study demonstrates that individual venom variation among V. b. berus living in particular area of Eastern Hungary might contribute to a wider range of clinical manifestations of V. b. berus envenoming than elsewhere in Europe. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. 50 CFR 11.11 - Notice of violation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS CIVIL PROCEDURES Assessment Procedure § 11.11 Notice of violation. (a) A notice of violation (hereinafter “notice... requested, upon the person believed to be subject to a civil penalty (the respondent). The notice shall...

  18. 50 CFR 11.11 - Notice of violation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS CIVIL PROCEDURES Assessment Procedure § 11.11 Notice of violation. (a) A notice of violation (hereinafter “notice... requested, upon the person believed to be subject to a civil penalty (the respondent). The notice shall...

  19. 77 FR 64379 - Proposed Collection; Comment Request for Notice 2009-58

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... Notice 2009-58, Manufacturers' Certification of Specified Plug-in Electric Vehicles. DATES: Written... Electric Vehicles. OMB Number: 1545-2150. Notice Number: Notice 2009-58. Abstract: The American Recovery... certain new specified plug-in electric drive vehicles. This notice provides procedures for a vehicle...

  20. Just noticeable differences of open quotient and asymmetry coefficient in singing voice.

    PubMed

    Henrich, Nathalie; Sundin, Gunilla; Ambroise, Daniel; d'Alessandro, Christophe; Castellengo, Michèle; Doval, Boris

    2003-12-01

    This study aims to explore the perceptual relevance of the variations of glottal flow parameters and to what extent a small variation can be detected. Just Noticeable Differences (JNDs) have been measured for three values of open quotient (0.4, 0.6, and 0.8) and two values of asymmetry coefficient (2/3 and 0.8), and the effect of changes of vowel, pitch, vibrato, and amplitude parameters has been tested. Two main groups of subjects have been analyzed: a group of 20 untrained subjects and a group of 10 trained subjects. The results show that the JND for open quotient is highly dependent on the target value: an increase of the JND is noticed when the open quotient target value is increased. The relative JND is constant: deltaOq/Oq = 14% for the untrained and 10% for the trained. In the same way, the JND for asymmetry coefficient is also slightly dependent on the target value--an increase of the asymmetry coefficient value leads to a decrease of the JND. The results show that there is no effect from the selected vowel or frequency (two values have been tested), but that the addition of a vibrato has a small effect on the JND of open quotient. The choice of an amplitude parameter also has a great effect on the JND of open quotient.

  1. Analysis of the Anticancer Phytochemicals in Andrographis paniculata Nees. under Salinity Stress

    PubMed Central

    Valdiani, Alireza; Maziah, Mahmood; Saad, Mohd Said

    2013-01-01

    Salinity causes the adverse effects in all physiological processes of plants. The present study aimed to investigate the potential of salt stress to enhance the accumulation of the anticancer phytochemicals in Andrographis paniculata accessions. For this purpose, 70-day-old plants were grown in different salinity levels (0.18, 4, 8, 12, and 16 dSm−1) on sand medium. After inducing a period of 30-day salinity stress and before flowering, all plants were harvested and the data on morphological traits, proline content and the three anticancer phytochemicals, including andrographolide (AG), neoandrographolide (NAG), and 14-deoxy-11,12-didehydroandrographolide (DDAG), were measured. The results indicated that salinity had a significant effect on the aforementioned three anticancer phytochemicals. In addition, the salt tolerance index (STI) was significantly decreased, while, except for DDAG, the content of proline, the AG, and NAG was significantly increased (P ≤ 0.01). Furthermore, it was revealed that significant differences among accessions could happen based on the total dry weight, STI, AG, and NAG. Finally, we noticed that the salinity at 12 dSm−1 led to the maximum increase in the quantities of AG, NAG, and DDAG. In other words, under salinity stress, the tolerant accessions were capable of accumulating the higher amounts of proline, AG, and NAG than the sensitive accessions. PMID:24371819

  2. Finite cohesion due to chain entanglement in polymer melts.

    PubMed

    Cheng, Shiwang; Lu, Yuyuan; Liu, Gengxin; Wang, Shi-Qing

    2016-04-14

    Three different types of experiments, quiescent stress relaxation, delayed rate-switching during stress relaxation, and elastic recovery after step strain, are carried out in this work to elucidate the existence of a finite cohesion barrier against free chain retraction in entangled polymers. Our experiments show that there is little hastened stress relaxation from step-wise shear up to γ = 0.7 and step-wise extension up to the stretching ratio λ = 1.5 at any time before or after the Rouse time. In contrast, a noticeable stress drop stemming from the built-in barrier-free chain retraction is predicted using the GLaMM model. In other words, the experiment reveals a threshold magnitude of step-wise deformation below which the stress relaxation follows identical dynamics whereas the GLaMM or Doi-Edwards model indicates a monotonic acceleration of the stress relaxation dynamics as a function of the magnitude of the step-wise deformation. Furthermore, a sudden application of startup extension during different stages of stress relaxation after a step-wise extension, i.e. the delayed rate-switching experiment, shows that the geometric condensation of entanglement strands in the cross-sectional area survives beyond the reptation time τd that is over 100 times the Rouse time τR. Our results point to the existence of a cohesion barrier that can prevent free chain retraction upon moderate deformation in well-entangled polymer melts.

  3. Nanoscale Mobility of Aqueous Polyacrylic Acid in Dental Restorative Cements.

    PubMed

    Berg, Marcella C; Benetti, Ana R; Telling, Mark T F; Seydel, Tilo; Yu, Dehong; Daemen, Luke L; Bordallo, Heloisa N

    2018-03-28

    Hydrogen dynamics in a time range from hundreds of femtoseconds to nanoseconds can be directly analyzed using neutron spectroscopy, where information on the inelastic and quasi-elastic scattering, hereafter INS and QENS, can be obtained. In this study, we applied these techniques to understand how the nanoscale mobility of the aqueous solution of polyacrylic acid (PAA) used in conventional glass ionomer cements (GICs) changes under confinement. Combining the spectroscopic analysis with calorimetric results, we were able to separate distinct motions within both the liquid and the GICs. The QENS analysis revealed that the self-diffusion translational motion identified in the liquid is also visible in the GIC. However, as a result of the formation of the cement matrix and its setting, both translational diffusion and residence time differed from the PAA solution. When comparing the local diffusion obtained for the selected GIC, the only noticeable difference was observed for the slow dynamics associated with the polymer chain. Additionally, over short-term aging, progressive water binding to the polymer chain occurred in one of the investigated GICs. Finally, a considerable change in the density of the GIC without progressive water binding indicates an increased polymer cross-linking. Taken together, our results suggest that accurate and deep understanding of polymer-water binding, polymer cross-linking, as well as material density changes occurring during the maturation process of GIC are necessary for the development of advanced dental restorative materials.

  4. [PROGNOSTIC SIGNIFICANCE OF CHANGES OF BLOOD GLUCOSE LEVEL IN PATIENTS WITH THORACOABDOMINAL INJURIES.

    PubMed

    Sorokin, E P; Ponomarev, S V; Shilyaeva, Ye V; Bel'skih, Ye A; Gritsan, A I

    2016-07-01

    Background Currently, one of the causes of high morbidity and mortality is injuries. Predict the outcome of injuries - it is an important task of the treating physician. Trauma is a stress factor so to predict the outcome, you can use markers of stress, the most accessible ofwhich is blood glucose. to reveal the dynamics of the relationship between blood glucose levels and the outlook for the life ofpatients with thoracoabdominal injuries. A retrospective analysis of medical records of hospitalized patients were divided into two groups, depending on the outlook for the life of (favorable or unfavorable), and each of the groups - into two subgroups according to the presence or absence of signs of intoxication at admission. The subgroups were calculated and compared the mean blood glucose levels at different hours of hospital treatment. It was found that the average blood glucose levels at various hours of hospital stay were significantly higher in patients with poor outcome. The most noticeable was the difference in the first days of hospital treatment. Signs of intoxication was associated with lower values of glucose and a tendency to hypoglycaemia. In addition, among patients with high blood glucose ( 8 mg / dL) was observed over deaths in the first day of hospital stay. High blood glucose levels ( 8,0 mmol / L) in the first day of hospital treatment is a predictor ofpoor outcome in patients with thoracoabdominal injuries.

  5. Random and non-random mating populations: Evolutionary dynamics in meiotic drive.

    PubMed

    Sarkar, Bijan

    2016-01-01

    Game theoretic tools are utilized to analyze a one-locus continuous selection model of sex-specific meiotic drive by considering nonequivalence of the viabilities of reciprocal heterozygotes that might be noticed at an imprinted locus. The model draws attention to the role of viability selections of different types to examine the stable nature of polymorphic equilibrium. A bridge between population genetics and evolutionary game theory has been built up by applying the concept of the Fundamental Theorem of Natural Selection. In addition to pointing out the influences of male and female segregation ratios on selection, configuration structure reveals some noted results, e.g., Hardy-Weinberg frequencies hold in replicator dynamics, occurrence of faster evolution at the maximized variance fitness, existence of mixed Evolutionarily Stable Strategy (ESS) in asymmetric games, the tending evolution to follow not only a 1:1 sex ratio but also a 1:1 different alleles ratio at particular gene locus. Through construction of replicator dynamics in the group selection framework, our selection model introduces a redefining bases of game theory to incorporate non-random mating where a mating parameter associated with population structure is dependent on the social structure. Also, the model exposes the fact that the number of polymorphic equilibria will depend on the algebraic expression of population structure. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. 7 CFR 319.55 - Notice of quarantine.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 5 2014-01-01 2014-01-01 false Notice of quarantine. 319.55 Section 319.55... SERVICE, DEPARTMENT OF AGRICULTURE FOREIGN QUARANTINE NOTICES Rice Quarantine § 319.55 Notice of quarantine. (a) The fact has been determined by the Secretary of Agriculture, and notice is hereby given, (1...

  7. 76 FR 60077 - Maryland; Amendment No. 3 to Notice of an Emergency Declaration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-3335-EM; Docket ID FEMA-2011-0001] Maryland; Amendment No. 3 to Notice of an Emergency Declaration AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: This notice amends the notice...

  8. 40 CFR 135.2 - Service of notice.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.2 Service of notice. (a) Notice of intent to file... such violation is alleged to have occurred, and the chief administrative officer of the water pollution...

  9. 40 CFR 135.3 - Contents of notice.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Contents of notice. 135.3 Section 135.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.3 Contents of notice. (a) Violation of...

  10. 40 CFR 135.3 - Contents of notice.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Contents of notice. 135.3 Section 135.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.3 Contents of notice. (a) Violation of...

  11. 40 CFR 135.2 - Service of notice.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.2 Service of notice. (a) Notice of intent to file... such violation is alleged to have occurred, and the chief administrative officer of the water pollution...

  12. 40 CFR 135.3 - Contents of notice.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 23 2012-07-01 2012-07-01 false Contents of notice. 135.3 Section 135.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.3 Contents of notice. (a) Violation of...

  13. 40 CFR 135.2 - Service of notice.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.2 Service of notice. (a) Notice of intent to file... such violation is alleged to have occurred, and the chief administrative officer of the water pollution...

  14. 40 CFR 135.2 - Service of notice.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.2 Service of notice. (a) Notice of intent to file... such violation is alleged to have occurred, and the chief administrative officer of the water pollution...

  15. 40 CFR 135.3 - Contents of notice.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Contents of notice. 135.3 Section 135.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Clean Water Act § 135.3 Contents of notice. (a) Violation of standard...

  16. 78 FR 15124 - Open Meeting of the Taxpayer Advocacy Panel Notices and Correspondence Project Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-08

    ... Notices and Correspondence Project Committee AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of meeting. SUMMARY: An open meeting of the Taxpayer Advocacy Panel Notices and Correspondence... Notices and Correspondence Project Committee will be held Wednesday, April 10, 2013, at 12 p.m. Eastern...

  17. 75 FR 57050 - Iowa; Amendment No. 6 to Notice of a Major Disaster Declaration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Internal Agency Docket No. FEMA-1930-DR; Docket ID FEMA-2010-0002] Iowa; Amendment No. 6 to Notice of a Major Disaster Declaration AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: This notice amends the notice...

  18. 77 FR 65605 - Proposed Collection; Comment Request for Notice 97-45

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-29

    ... Notice 97-45, Highly Compensated Employee Definition. DATES: Written comments should be received on or... INFORMATION: Title: Highly Compensated Employee Definition. OMB Number: 1545-1550. Notice Number: Notice 97-45. Abstract: Notice 97-45 provides guidance on the definition of highly compensated employee (HCE) within the...

  19. 40 CFR 135.13 - Timing of notice.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Timing of notice. 135.13 Section 135.13 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Safe Drinking Water Act § 135.13 Timing of notice. No action...

  20. 40 CFR 135.12 - Contents of notice.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Contents of notice. 135.12 Section 135.12 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Safe Drinking Water Act § 135.12 Contents of notice. (a...

  1. 40 CFR 135.13 - Timing of notice.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 22 2011-07-01 2011-07-01 false Timing of notice. 135.13 Section 135.13 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Safe Drinking Water Act § 135.13 Timing of notice. No action...

  2. 40 CFR 135.12 - Contents of notice.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Contents of notice. 135.12 Section 135.12 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS PRIOR NOTICE OF CITIZEN SUITS Prior Notice Under the Safe Drinking Water Act § 135.12 Contents of notice. (a...

  3. 29 CFR 2590.609-2 - National Medical Support Notice.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false National Medical Support Notice. 2590.609-2 Section 2590..., Qualified Medical Child Support Orders, Coverage for Adopted Children § 2590.609-2 National Medical Support Notice. (a) This section promulgates the National Medical Support Notice (the Notice), as mandated by...

  4. 29 CFR 2590.609-2 - National Medical Support Notice.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false National Medical Support Notice. 2590.609-2 Section 2590..., Qualified Medical Child Support Orders, Coverage for Adopted Children § 2590.609-2 National Medical Support Notice. (a) This section promulgates the National Medical Support Notice (the Notice), as mandated by...

  5. 42 CFR 488.434 - Civil money penalties: Notice of penalty.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES... procedures for all non-State operated NFs when the State takes the action. (2) The State's notice must— (i...: Notice of penalty. (a) CMS notice of penalty. (1) CMS sends a written notice of the penalty to the...

  6. 42 CFR 488.434 - Civil money penalties: Notice of penalty.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES... procedures for all non-State operated NFs when the State takes the action. (2) The State's notice must— (i...: Notice of penalty. (a) CMS notice of penalty. (1) CMS sends a written notice of the penalty to the...

  7. 42 CFR 488.434 - Civil money penalties: Notice of penalty.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES... procedures for all non-State operated NFs when the State takes the action. (2) The State's notice must— (i...: Notice of penalty. (a) CMS notice of penalty. (1) CMS sends a written notice of the penalty to the...

  8. 42 CFR 488.434 - Civil money penalties: Notice of penalty.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES... procedures for all non-State operated NFs when the State takes the action. (2) The State's notice must— (i...: Notice of penalty. (a) CMS notice of penalty. (1) CMS sends a written notice of the penalty to the...

  9. 42 CFR 488.434 - Civil money penalties: Notice of penalty.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION SURVEY, CERTIFICATION, AND ENFORCEMENT PROCEDURES... procedures for all non-State operated NFs when the State takes the action. (2) The State's notice must— (i...: Notice of penalty. (a) CMS notice of penalty. (1) CMS sends a written notice of the penalty to the...

  10. 78 FR 25484 - Advisory Committee for Engineering; Notice of Meeting; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... NATIONAL SCIENCE FOUNDATION Advisory Committee for Engineering; Notice of Meeting; Correction This document corrects a notice that was published in the Federal Register on April 24, 2013 on page 24239. The... Science and Engineering, 1115; Notice of Meeting All other information in the April 24, 2013 notice...

  11. 16 CFR 313.9 - Delivering privacy and opt out notices.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... refrain from sending any information regarding the customer relationship, and your current privacy notice...) Annual notices only. You may reasonably expect that a customer will receive actual notice of your annual privacy notice if: (1) The customer uses your web site to access financial products and services...

  12. 16 CFR 680.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 680.26 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT AFFILIATE MARKETING... reasonably be expected to receive actual notice if the affiliate providing the notice: (1) Hand-delivers a... electronic disclosures by e-mail from the affiliate providing the notice; or (4) Posts the notice on the...

  13. 16 CFR 680.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 680.26 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT AFFILIATE MARKETING... reasonably be expected to receive actual notice if the affiliate providing the notice: (1) Hand-delivers a... electronic disclosures by e-mail from the affiliate providing the notice; or (4) Posts the notice on the...

  14. 16 CFR 680.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 680.26 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT AFFILIATE MARKETING... reasonably be expected to receive actual notice if the affiliate providing the notice: (1) Hand-delivers a... electronic disclosures by e-mail from the affiliate providing the notice; or (4) Posts the notice on the...

  15. 16 CFR 680.26 - Delivery of opt-out notices.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 680.26 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT AFFILIATE MARKETING... reasonably be expected to receive actual notice if the affiliate providing the notice: (1) Hand-delivers a... electronic disclosures by e-mail from the affiliate providing the notice; or (4) Posts the notice on the...

  16. 17 CFR 171.21 - Notice of final decision.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Futures Association shall promptly serve all parties, as well as the Proceedings Clerk and the Secretary... decision issued by the National Futures Association. (b) Content of the notice. At a minimum, the notice... notice. (1) If the National Futures Association issues a notice of a final decision subject to these...

  17. 17 CFR 171.21 - Notice of final decision.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Futures Association shall promptly serve all parties, as well as the Proceedings Clerk and the Secretary... decision issued by the National Futures Association. (b) Content of the notice. At a minimum, the notice... notice. (1) If the National Futures Association issues a notice of a final decision subject to these...

  18. 17 CFR 171.21 - Notice of final decision.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Futures Association shall promptly serve all parties, as well as the Proceedings Clerk and the Secretary... decision issued by the National Futures Association. (b) Content of the notice. At a minimum, the notice... notice. (1) If the National Futures Association issues a notice of a final decision subject to these...

  19. 17 CFR 171.21 - Notice of final decision.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Futures Association shall promptly serve all parties, as well as the Proceedings Clerk and the Secretary... decision issued by the National Futures Association. (b) Content of the notice. At a minimum, the notice... notice. (1) If the National Futures Association issues a notice of a final decision subject to these...

  20. 17 CFR 171.21 - Notice of final decision.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Futures Association shall promptly serve all parties, as well as the Proceedings Clerk and the Secretary... decision issued by the National Futures Association. (b) Content of the notice. At a minimum, the notice... notice. (1) If the National Futures Association issues a notice of a final decision subject to these...

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