Sample records for review basic concepts

  1. Boehm Test of Basic Concepts-Revised. Review.

    ERIC Educational Resources Information Center

    Padula, Janice

    1988-01-01

    The manual for the Boehm Test of Basic Concepts-Revised (1986) is reviewed. The test measures a child's knowledge of relational concepts. The revised version, eliminating some imperfections of the original, will continue to be a useful test of verbal concept acquisition. Cautions necessary while using the test are discussed. (SLD)

  2. Using a Thyroid Case Study and Error Plausibility to Introduce Basic Lab Skills

    ERIC Educational Resources Information Center

    Browning, Samantha; Urschler, Margaret; Meidl, Katherine; Peculis, Brenda; Milanick, Mark

    2017-01-01

    We describe a 3-hour session that provides students with the opportunity to review basic lab concepts and important techniques using real life scenarios. We began with two separate student-engaged discussions to remind/reinforce some basic concepts in physiology and review calculations with respect to chemical compounds. This was followed by…

  3. Meeting Basic Needs Is Not beyond Our Reach.

    ERIC Educational Resources Information Center

    Haq, Mahbub ul

    1978-01-01

    Reviews the status of the continuing debate on the concept of "basic needs" in development policy for the world's poorest countries, reprinted from a World Bank report. Discusses "core" basic needs (food and nutrition, drinking water, basic health, shelter, and basic education) and possible operational policies. (MF)

  4. Item Response Theory: A Basic Concept

    ERIC Educational Resources Information Center

    Mahmud, Jumailiyah

    2017-01-01

    With the development in computing technology, item response theory (IRT) develops rapidly, and has become a user friendly application in psychometrics world. Limitation in classical theory is one aspect that encourages the use of IRT. In this study, the basic concept of IRT will be discussed. In addition, it will briefly review the ability…

  5. Pre-schoolers Learn at Home.

    ERIC Educational Resources Information Center

    Smith, Penny

    1985-01-01

    Reviews: "ArithMagic (Counting, Addition, Subtraction)" which uses graphics to illustrate/review basic arithmetic concepts; "The Sweet Shop" which uses graphics (and a character called Mr. Jellybean) to teach arithmetic concepts; and "Math Magic," a monster-filled arcade game that teaches addition and subtraction.…

  6. Measuring social science concepts in pharmacy education research: From definition to item analysis of self-report instruments.

    PubMed

    Cor, M Ken

    Interpreting results from quantitative research can be difficult when measures of concepts are constructed poorly, something that can limit measurement validity. Social science steps for defining concepts, guidelines for limiting construct-irrelevant variance when writing self-report questions, and techniques for conducting basic item analysis are reviewed to inform the design of instruments to measure social science concepts in pharmacy education research. Based on a review of the literature, four main recommendations emerge: These include: (1) employ a systematic process of conceptualization to derive nominal definitions; (2) write exact and detailed operational definitions for each concept, (3) when creating self-report questionnaires, write statements and select scales to avoid introducing construct-irrelevant variance (CIV); and (4) use basic item analysis results to inform instrument revision. Employing recommendations that emerge from this review will strengthen arguments to support measurement validity which in turn will support the defensibility of study finding interpretations. An example from pharmacy education research is used to contextualize the concepts introduced. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Workplace Math II: Math Works!

    ERIC Educational Resources Information Center

    Wilson, Nancy; Goschen, Claire

    This learning module, a continuation of the math I module, provides review and practice of the concepts explored in the earlier module at an intermediate level involving workplace problems. The following concepts are covered: instruction in performing basic computations, using general numerical concepts such as whole numbers, fractions, decimals,…

  8. [The Basic-Symptom Concept and its Influence on Current International Research on the Prediction of Psychoses].

    PubMed

    Schultze-Lutter, F

    2016-12-01

    The early detection of psychoses has become increasingly relevant in research and clinic. Next to the ultra-high risk (UHR) approach that targets an immediate risk of developing frank psychosis, the basic symptom approach that targets the earliest possible detection of the developing disorder is being increasingly used worldwide. The present review gives an introduction to the development and basic assumptions of the basic symptom concept, summarizes the results of studies on the specificity of basic symptoms for psychoses in different age groups as well as on studies of their psychosis-predictive value, and gives an outlook on future results. Moreover, a brief introduction to first recent imaging studies is given that supports one of the main assumptions of the basic symptom concept, i. e., that basic symptoms are the most immediate phenomenological expression of the cerebral aberrations underlying the development of psychosis. From this, it is concluded that basic symptoms might be able to provide important information on future neurobiological research on the etiopathology of psychoses. © Georg Thieme Verlag KG Stuttgart · New York.

  9. Basic principles of management for cervical spine trauma.

    PubMed

    O'Dowd, J K

    2010-03-01

    This article reviews the basic principles of management of cervical trauma. The technique and critical importance of careful assessment is described. Instability is defined, and the incidence of a second injury is highlighted. The concept of spinal clearance is discussed. Early reduction and stabilisation techniques are described, and the indications, and approach for surgery reviewed. The importance of the role of post-injury rehabilitation is identified.

  10. A review of computer evacuation models and their data needs.

    DOT National Transportation Integrated Search

    1994-05-01

    This document reviews the history and current status of computer models of the evacuation of an airliner cabin. Basic concepts upon which evacuation models are based are discussed, followed by a review of the Civil Aerospace Medical Institute s effor...

  11. FORWARD: DESERTIFICATION IN THE MEDITERRANEAN REGION: A SECURITY ISSUE

    EPA Science Inventory

    The Workshop focused on two basic concepts: security and desertification and their linkages. Since the end of the Cold War, traditional security concepts based on national sovereignty and territorial security have increasingly been brought under review. Currently, a broader defin...

  12. Thermal evaluation of advanced solar dynamic heat receiver performance

    NASA Technical Reports Server (NTRS)

    Crane, Roger A.

    1989-01-01

    The thermal performance of a variety of concepts for thermal energy storage as applied to solar dynamic applications is discussed. It is recognized that designs providing large thermal gradients or large temperature swings during orbit are susceptible to early mechanical failure. Concepts incorporating heat pipe technology may encounter operational limitations over sufficiently large ranges. By reviewing the thermal performance of basic designs, the relative merits of the basic concepts are compared. In addition the effect of thermal enhancement and metal utilization as applied to each design provides a partial characterization of the performance improvements to be achieved by developing these technologies.

  13. Teaching basic science to optimize transfer.

    PubMed

    Norman, Geoff

    2009-09-01

    Basic science teachers share the concern that much of what they teach is soon forgotten. Although some evidence suggests that relatively little basic science is forgotten, it may not appear so, as students commonly have difficulty using these concepts to solve or explain clinical problems: This phenomenon, using a concept learned in one context to solve a problem in a different context, is known to cognitive psychologists as transfer. The psychology literature shows that transfer is difficult; typically, even though students may know a concept, fewer than 30% will be able to use it to solve new problems. However a number of strategies to improve transfer can be adopted at the time of initial teaching of the concept, in the use of exemplars to illustrate the concept, and in practice with additional problems. In this article, we review the literature in psychology to identify practical strategies to improve transfer. Critical review of psychology literature to identify factors that enhance or impede transfer. There are a number of strategies available to teachers to facilitate transfer. These include active problem-solving at the time of initial learning, imbedding the concept in a problem context, using everyday analogies, and critically, practice with multiple dissimilar problems. Further, mixed practice, where problems illustrating different concepts are mixed together, and distributed practice, spread out over time, can result in significant and large gains. Transfer is difficult, but specific teaching strategies can enhance this skill by factors of two or three.

  14. Basic principles of management for cervical spine trauma

    PubMed Central

    2009-01-01

    This article reviews the basic principles of management of cervical trauma. The technique and critical importance of careful assessment is described. Instability is defined, and the incidence of a second injury is highlighted. The concept of spinal clearance is discussed. Early reduction and stabilisation techniques are described, and the indications, and approach for surgery reviewed. The importance of the role of post-injury rehabilitation is identified. PMID:19701655

  15. Generalizations Related to Concepts Important for Youth Orientation to the World of Work.

    ERIC Educational Resources Information Center

    Warren, Mary A.; And Others

    A basic first step in building a curriculum contributing to the orientation of youth to world of work is identification of concepts important to that orientation. In this study, the generalizations within the concept framework were identified through a developmental process of analysis and synthesis, including a review of current literature, a…

  16. TRAINING IN INDUSTRY--THE MANAGEMENT OF LEARNING.

    ERIC Educational Resources Information Center

    BASS, BERNARD M.; VAUGHAN, JAMES A.

    THE PRINCIPLES OF LEARNING BEHAVIOR DERIVED THROUGH LABORATORY STUDY CAN BE EXTENDED TO EXPLAIN MUCH OF THE COMPLEX LEARNING REQUIRED IN INDUSTRIAL TRAINING PROGRAMS. A REVIEW OF THE BASIC PRINCIPLES OF HUMAN LEARNING INTRODUCES FOUR BASIC CONCEPTS--DRIVE, STIMULUS, RESPONSE, AND REINFORCER--AND DISCUSSES CLASSICAL AND INSTRUMENTAL CONDITIONING…

  17. Motivation in Education.

    ERIC Educational Resources Information Center

    Ray, Nancy L.

    This paper presents basic principles and theories of motivation, attempts to provide a better understanding of the concept, and explores the role motivation plays in learning. Basic theories of motivation are reviewed including: Freud's belief in motivation by the id, unconscious forces, and sexual stages; Jung and Adler's belief that people are…

  18. Digital Simulation and Modelling.

    ERIC Educational Resources Information Center

    Hawthorne, G. B., Jr.

    A basically tutorial point of view is taken in this general discussion. The author examines the basic concepts and principles of simulation and modelling and the application of digital computers to these tasks. Examples of existing simulations, a discussion of the applicability and feasibility of simulation studies, a review of simulation…

  19. [Introduction to Exploratory Factor Analysis (EFA)].

    PubMed

    Martínez, Carolina Méndez; Sepúlveda, Martín Alonso Rondón

    2012-03-01

    Exploratory Factor Analysis (EFA) has become one of the most frequently used statistical techniques, especially in the medical and social sciences. Given its popularity, it is essential to understand the basic concepts necessary for its proper application and to take into consideration the main strengths and weaknesses of this technique. To present in a clear and concise manner the main applications of this technique, to determine the basic requirements for its use providing a description step by step of its methodology, and to establish the elements that must be taken into account during its preparation in order to not incur in erroneous results and interpretations. Narrative review. This review identifies the basic concepts and briefly describes the objectives, design, assumptions, and methodology to achieve factor derivation, global adjustment evaluation, and adequate interpretation of results. Copyright © 2012 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

  20. Suggestions for Realization Rather than Professionalization in Adult Basic Education.

    ERIC Educational Resources Information Center

    Allen, Fred

    1987-01-01

    A literature review shows lack of consensus in defining adult education and rejection of the application of the traditional model of professionalism to adult basic education (ABE). Carl Rogers' concept of substituting realization for professionalization, as well as the literature of staff preservice and inservice training, can help practitioners…

  1. Soapy Science. Teaching Science.

    ERIC Educational Resources Information Center

    Leyden, Michael

    1997-01-01

    Describes a science and math activity that involves bubbles, shapes, colors, and solid geometry. Students build geometric shapes with soda straws and submerge the shapes in soapy water, allowing them to review basic geometry concepts, test hypotheses, and learn about other concepts such as diffraction, interference colors, and evaporation. (TJQ)

  2. Prospective Science Teachers' Conceptions about Astronomical Subjects

    ERIC Educational Resources Information Center

    Küçüközer, Hüseyin

    2007-01-01

    The main objective of this study was to identify prospective science teachers' conceptions on basic astronomical phenomena. A questionnaire consisting of nine open-ended questions was administered to 327 prospective science teachers. The questionnaire was constructed after extensive review of the literature and took into consideration the reported…

  3. Determining the Feasibility of an Annual Commissioner's Report of the Mastery of Basic Skills by Florida Citizens. Basic Literacy and Basic Skills Technical Report No. 1.

    ERIC Educational Resources Information Center

    Powell, William R.; And Others

    This report recommends that an annual report be made to the citizens of Florida about the state of literacy in Florida. The concept of literacy is defined in terms of levels of literacy and basic skills required to achieve the different levels. A review of the literature on literacy is the basis for three suggested levels of literacy: (1)…

  4. [Basic principles and methodological considerations of health economic evaluations].

    PubMed

    Loza, Cesar; Castillo-Portilla, Manuel; Rojas, José Luis; Huayanay, Leandro

    2011-01-01

    Health Economics is an essential instrument for health management, and economic evaluations can be considered as tools assisting the decision-making process for the allocation of resources in health. Currently, economic evaluations are increasingly being used worldwide, thus encouraging evidence-based decision-making and seeking efficient and rational alternatives within the framework of health services activities. In this review, we present an overview and define the basic types of economic evaluations, with emphasis on complete Economic Evaluations (EE). In addition, we review key concepts regarding the perspectives from which EE can be conducted, the types of costs that can be considered, the time horizon, discounting, assessment of uncertainty and decision rules. Finally, we describe concepts about the extrapolation and spread of economic evaluations in health.

  5. Understanding Thermal Equilibrium through Activities

    ERIC Educational Resources Information Center

    Pathare, Shirish; Huli, Saurabhee; Nachane, Madhura; Ladage, Savita; Pradhan, Hemachandra

    2015-01-01

    Thermal equilibrium is a basic concept in thermodynamics. In India, this concept is generally introduced at the first year of undergraduate education in physics and chemistry. In our earlier studies (Pathare and Pradhan 2011 "Proc. episteme-4 Int. Conf. to Review Research on Science Technology and Mathematics Education" pp 169-72) we…

  6. Action Research of Computer-Assisted-Remediation of Basic Research Concepts.

    ERIC Educational Resources Information Center

    Packard, Abbot L.; And Others

    This study investigated the possibility of creating a computer-assisted remediation program to assist students having difficulties in basic college research and statistics courses. A team approach involving instructors and students drove the research into and creation of the computer program. The effect of student use was reviewed by looking at…

  7. Nanotechnology Review: Molecular Electronics to Molecular Motors

    NASA Technical Reports Server (NTRS)

    Srivastava, Deepak; Saini, Subhash (Technical Monitor)

    1998-01-01

    Reviewing the status of current approaches and future projections, as already published in scientific journals and books, the talk will summarize the direction in which computational and experimental nanotechnologies are progressing. Examples of nanotechnological approaches to the concepts of design and simulation of carbon nanotube based molecular electronic and mechanical devices will be presented. The concepts of nanotube based gears and motors will be discussed. The above is a non-technical review talk which covers long term precompetitive basic research in already published material that has been presented before many US scientific meeting audiences.

  8. Predators and Prey

    ERIC Educational Resources Information Center

    Kramm, Kenneth R.

    1975-01-01

    Reviews basic concepts of predator-prey interaction, encourages the presentation of the predator's role and describes a model of predator behavior to be used in secondary school or college classes. (LS)

  9. Basic Concepts of CNS Development.

    ERIC Educational Resources Information Center

    Nowakowski, R. S.

    1987-01-01

    The goals of this review are to: (1) provide a set of concepts to aid in the understanding of complex processes which occur during central nervous system (CNS) development; (2) illustrate how they contribute to our knowlege of adult brain anatomy; and (3) delineate how modifications of normal developmental processes may affect the structure and…

  10. Sport and Social Organization.

    ERIC Educational Resources Information Center

    Nixon, Howard L., II

    Sport is examined in relation to a number of basic aspects of social organization. Each of the seven sections includes a brief clarification of the key sociological concepts used for analysis, a consideration of various applications of those concepts to sport, and a review and discussion of what is known about specific aspects of sport in relation…

  11. Is Acculturation in Hispanic Health Research a Flawed Concept? JSRI Working Paper.

    ERIC Educational Resources Information Center

    Ponce, Carlos; Comer, Brendon

    Some health researchers have used the concept of acculturation to explain health behaviors or illnesses prevalent among Hispanic people. This paper reviews studies in health, educational, and social science research among Hispanics and argues that acculturation studies are seriously limited by several basic conceptual and methodological problems.…

  12. Broadening Rehabilitation Education and Research through Cultural Humility: A Conceptual Framework for Rehabilitation Counseling

    ERIC Educational Resources Information Center

    Hampton, Nan Zhang; Guillermo, Mari S.; Tucker, Mark; Nichols, Tayler

    2017-01-01

    Purpose: The purpose of this conceptual article is to present a framework that incorporates the concept of culture humility into effective rehabilitation services. Method: Based on a comprehensive literature review and theoretical integration, this article provides the reader with the basic concept of cultural humility, similarities and…

  13. Reproductive endocrinology of llamas and alpacas.

    PubMed

    Bravo, P W

    1994-07-01

    The physiology of reproduction with emphasis in endocrinology of llamas and alpacas is addressed. Basic concepts of ovarian follicular dynamics, endocrine events associated with induction of ovulation, corpus luteum formation, pregnancy, parturition, postpartum interval, puberty, and sexual behavior on the female are reviewed. Pathologic conditions of the reproductive process are also reviewed.

  14. Design review - A tool for all seasons.

    NASA Technical Reports Server (NTRS)

    Liberman, D. S.

    1972-01-01

    The origins of design review are considered together with questions of definitions. The main characteristics which distinguish the concept of design review discussed from the basic master-apprentice relationship include competence, objectivity, formality, and a systematic approach. Preliminary, major, and final reviews are the steps used in the management of the design and development process in each company. It is shown that the design review is generically a systems engineering milestone review with certain unique characteristics.

  15. An Illuminating Reaction.

    ERIC Educational Resources Information Center

    Matthews, Catherine E.

    1996-01-01

    Describes the use of carbide lights as an excellent mechanism for introducing or reviewing many basic chemistry concepts including elements and compounds, endothermic and exothermic reactions, physical and chemical changes, and balancing chemical equations. (JRH)

  16. Large-scale database searching using tandem mass spectra: looking up the answer in the back of the book.

    PubMed

    Sadygov, Rovshan G; Cociorva, Daniel; Yates, John R

    2004-12-01

    Database searching is an essential element of large-scale proteomics. Because these methods are widely used, it is important to understand the rationale of the algorithms. Most algorithms are based on concepts first developed in SEQUEST and PeptideSearch. Four basic approaches are used to determine a match between a spectrum and sequence: descriptive, interpretative, stochastic and probability-based matching. We review the basic concepts used by most search algorithms, the computational modeling of peptide identification and current challenges and limitations of this approach for protein identification.

  17. Minimize system cost by choosing optimal subsystem reliability and redundancy

    NASA Technical Reports Server (NTRS)

    Suich, Ronald C.; Patterson, Richard L.

    1993-01-01

    The basic question which we address in this paper is how to choose among competing subsystems. This paper utilizes both reliabilities and costs to find the subsystems with the lowest overall expected cost. The paper begins by reviewing some of the concepts of expected value. We then address the problem of choosing among several competing subsystems. These concepts are then applied to k-out-of-n: G subsystems. We illustrate the use of the authors' basic program in viewing a range of possible solutions for several different examples. We then discuss the implications of various solutions in these examples.

  18. Introduction to molecular topology: basic concepts and application to drug design.

    PubMed

    Gálvez, Jorge; Gálvez-Llompart, María; García-Domenech, Ramón

    2012-09-01

    In this review it is dealt the use of molecular topology (MT) in the selection and design of new drugs. After an introduction of the actual methods used for drug design, the basic concepts of MT are defined, including examples of calculation of topological indices, which are numerical descriptors of molecular structures. The goal is making this calculation familiar to the potential students and allowing a straightforward comprehension of the topic. Finally, the achievements obtained in this field are detailed, so that the reader can figure out the great interest of this approach.

  19. Twenty Years of Basic Vocational Education Provision in Spain: Changes and Trends

    ERIC Educational Resources Information Center

    Marhuenda-Fluixa, Fernando; Salvà, Francesca; Navas Saurin, Almudena A.; Abiétar López, Míriam

    2015-01-01

    Our contribution attempts to review basic vocational education programmes in Spain over the past 25 years. We intend to compare the evolution of these programmes in terms of conception and conditions of delivery in order to find out how different they are as skill-formation and remedial systems, as well as analysing how different political views…

  20. A brief review of the clinical anatomy of the vestibular-ocular connections-how much do we know?

    PubMed

    Bronstein, A M; Patel, M; Arshad, Q

    2015-02-01

    The basic connectivity from the vestibular labyrinth to the eye muscles (vestibular ocular reflex, VOR) has been elucidated in the past decade, and we summarise this in graphic format. We also review the concept of 'velocity storage', a brainstem integrator that prolongs vestibular responses. Finally, we present new discoveries of how complex visual stimuli, such as binocular rivalry, influence VOR processing. In contrast to the basic brainstem circuits, cortical vestibular circuits are far from being understood, but parietal-vestibular nuclei projections are likely to be involved.

  1. The evolutionary origin of the vertebrate body plan: the problem of head segmentation.

    PubMed

    Onai, Takayuki; Irie, Naoki; Kuratani, Shigeru

    2014-01-01

    The basic body plan of vertebrates, as typified by the complex head structure, evolved from the last common ancestor approximately 530 Mya. In this review, we present a brief overview of historical discussions to disentangle the various concepts and arguments regarding the evolutionary development of the vertebrate body plan. We then explain the historical transition of the arguments about the vertebrate body plan from merely epistemological comparative morphology to comparative embryology as a scientific treatment on this topic. Finally, we review the current progress of molecular evidence regarding the basic vertebrate body plan, focusing on the link between the basic vertebrate body plan and the evolutionarily conserved developmental stages (phylotypic stages).

  2. Developmental Neurotoxicology: History and Outline of ...

    EPA Pesticide Factsheets

    The present work provides a brief review of basic concepts in developmental neurotoxicology, as well as current representative testing guidelines for evaluating developmental neurotoxicity (DNT) of xenobiotics. Historically, DNT was initially recognized as a “functional” teratogenicity: the main concern was that prenatal and/or early postnatal exposures to chemicals during critical periods of central nervous system (CNS) development would cause later functional abnormalities of the brain. Current internationally harmonized DNT study guidelines are thus intended to predict adverse effects of test compounds on the developing CNS by observing such postnatal parameters as motor activity, startle response, and learning and memory, as well as neropathological alterations. The reliability of current DNT study guidelines and sensitivity of testing methodologies recommended in these guidelines have been confirmed by retrospective evaluations of the many international and domestic collaborative validation studies in developed nations including Japan. Invited review with brief review of basic concepts in developmental neurotoxicology, as well as current representative testing guidelines for evaluating developmental neurotoxicity (DNT) of xenobiotics.

  3. Issues in Business and Medical Education: Brief Literature Review on Strategic Management of Health Care Institutions.

    ERIC Educational Resources Information Center

    Smith, Alan D.

    The literature on the use of strategic management principles by health care organizations is reviewed. After considering basic concepts of strategic management and managerial problems in nonprofit organizations, strategic planning and management of health care organizations are covered. Attention is directed to the health care environment,…

  4. What Works Clearinghouse Quick Review: "Academic Music: Music Instruction to Engage Third-Grade Students in Learning Basic Fraction Concepts"

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2012

    2012-01-01

    The study examined the effectiveness of an intervention designed to teach mathematical concepts through music. Specifically, it investigated the effect of the intervention on third-grade students' understanding of fractions. Sixty-seven students from one northern California elementary school participated in the study over a period of six weeks; of…

  5. Politics and the Movie

    ERIC Educational Resources Information Center

    Funderburk, Charles

    1978-01-01

    Explains how the use of feature-length motion pictures, combined with interesting readings, can generate enthusiasm, discussion, and analysis of basic political ideas, concepts, and values. Reviews costs and identifies specific movies and readings on various political topics. (AV)

  6. AEROSAT Access Control Summary

    DOT National Transportation Integrated Search

    1976-10-01

    The report consists of three basic sections. Section 2 is a discussion of the communications concepts germane to AEROSAT access control. It defines and reviews the principles of multiplexing, multiple access, demand access, and access control and rel...

  7. Aerosat Access Control Summary

    DOT National Transportation Integrated Search

    1976-10-01

    The report consists of three basic sections. Section 2 is a discussion of the communications concepts germane to AEROSAT access control. It defines and reviews the principles of multiplexing, multiple access, demand access, and access control and rel...

  8. DOE Fundamentals Handbook: Mathematics, Volume 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-06-01

    The Mathematics Fundamentals Handbook was developed to assist nuclear facility operating contractors provide operators, maintenance personnel, and the technical staff with the necessary fundamentals training to ensure a basic understanding of mathematics and its application to facility operation. The handbook includes a review of introductory mathematics and the concepts and functional use of algebra, geometry, trigonometry, and calculus. Word problems, equations, calculations, and practical exercises that require the use of each of the mathematical concepts are also presented. This information will provide personnel with a foundation for understanding and performing basic mathematical calculations that are associated with various DOE nuclearmore » facility operations.« less

  9. DOE Fundamentals Handbook: Mathematics, Volume 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-06-01

    The Mathematics Fundamentals Handbook was developed to assist nuclear facility operating contractors provide operators, maintenance personnel, and the technical staff with the necessary fundamentals training to ensure a basic understanding of mathematics and its application to facility operation. The handbook includes a review of introductory mathematics and the concepts and functional use of algebra, geometry, trigonometry, and calculus. Word problems, equations, calculations, and practical exercises that require the use of each of the mathematical concepts are also presented. This information will provide personnel with a foundation for understanding and performing basic mathematical calculations that are associated with various DOE nuclearmore » facility operations.« less

  10. Microcomputers! Applications to Physics Teaching.

    ERIC Educational Resources Information Center

    Tinker, Robert F.; Stringer, Gene A.

    1978-01-01

    Reviews the use of computers in various aspects of physics teaching. Introduces some basic hardware and software concepts and jargon. Illustrates these ideas using four vastly different microcomputers, with prices, to help in choosing the right educational computer system. (GA)

  11. Railroad Classification Yard Technology : An Introductory Analysis of Functions and Operations

    DOT National Transportation Integrated Search

    1975-05-01

    A review of the basic operating characteristics and functions of railroad classification yards is presented. Introductory descriptions of terms, concepts, and problems of railroad operations involving classification yards are included in an attempt t...

  12. Principles of Quantitative MR Imaging with Illustrated Review of Applicable Modular Pulse Diagrams.

    PubMed

    Mills, Andrew F; Sakai, Osamu; Anderson, Stephan W; Jara, Hernan

    2017-01-01

    Continued improvements in diagnostic accuracy using magnetic resonance (MR) imaging will require development of methods for tissue analysis that complement traditional qualitative MR imaging studies. Quantitative MR imaging is based on measurement and interpretation of tissue-specific parameters independent of experimental design, compared with qualitative MR imaging, which relies on interpretation of tissue contrast that results from experimental pulse sequence parameters. Quantitative MR imaging represents a natural next step in the evolution of MR imaging practice, since quantitative MR imaging data can be acquired using currently available qualitative imaging pulse sequences without modifications to imaging equipment. The article presents a review of the basic physical concepts used in MR imaging and how quantitative MR imaging is distinct from qualitative MR imaging. Subsequently, the article reviews the hierarchical organization of major applicable pulse sequences used in this article, with the sequences organized into conventional, hybrid, and multispectral sequences capable of calculating the main tissue parameters of T1, T2, and proton density. While this new concept offers the potential for improved diagnostic accuracy and workflow, awareness of this extension to qualitative imaging is generally low. This article reviews the basic physical concepts in MR imaging, describes commonly measured tissue parameters in quantitative MR imaging, and presents the major available pulse sequences used for quantitative MR imaging, with a focus on the hierarchical organization of these sequences. © RSNA, 2017.

  13. "What's Wrong in This Picture?": Response to Motta et al.'s Review of Human Figure Drawings.

    ERIC Educational Resources Information Center

    Gresham, Frank M.

    1993-01-01

    Responds to article (Motta, Little, and Tobin, this issue) which reviewed data-based studies on figure drawings and found little support for their validity or use in assessing personality, behavior, emotion, or intellectual functioning. Agrees with original article, suggesting that arguments be couched in terms of three basic concepts: illusory…

  14. Occupational Stress. Proceedings of the Conference on Occupational Stress (Los Angeles, California, November 3, 1977).

    ERIC Educational Resources Information Center

    California Univ., Los Angeles. Inst. of Industrial Relations.

    The proceedings of a conference on occupational stress are contained in this report. Presentation titles include the following: "Basic Concepts of Organizational Stress--Causes and Problems,""Occupational Sources of Stress: A Review of the Literature Relating to Coronary Heart Disease and Mental Ill Health,""A Review of [National Institute for…

  15. Study of basic physical processes in liquid rocket engines

    NASA Technical Reports Server (NTRS)

    Wu, S. T.; Chen, C. P.

    1992-01-01

    Inconsistencies between analytical results and measurements for liquid rocket thrust chamber performance, which escape suitable explanations, have motivated the examination of the basic phys ical modeling formulations as to their unlimited application. The publication of Prof. D. Straub's book, 'Thermofluid-dynamics of Optimized Rocket Propulsions,' further stimulated the interest of understanding the gas dynamic relationships in chemically reacting mixtures. A review of other concepts proposed by Falk-Ruppel (Gibbsian Thermodynamics), Straub (Alternative Theory, AT), Prigogine (Non-Equilibrium Thermodynamics), Boltzmann (Kinetic Theory), and Truesdell (Rational Mechanism) has been made to obtain a better understanding of the Navier-Stokes equation, which is now used extensively for chemically reacting flow treatment in combustion chambers. In addition to the study of the different concepts, two workshops were conducted to clarify some of the issues. The first workshop centered on Falk-Ruppel's new 'dynamics' concept, while the second one concentrated on Straub's AT. In this report brief summaries of the reviewed philosophies are presented and compared with the classical Navier-Stokes formulation in a tabular arrangement. Also the highlights of both workshops are addressed.

  16. An analysis of possible applications of fuzzy set theory to the actuarial credibility theory

    NASA Technical Reports Server (NTRS)

    Ostaszewski, Krzysztof; Karwowski, Waldemar

    1992-01-01

    In this work, we review the basic concepts of actuarial credibility theory from the point of view of introducing applications of the fuzzy set-theoretic method. We show how the concept of actuarial credibility can be modeled through the fuzzy set membership functions and how fuzzy set methods, especially fuzzy pattern recognition, can provide an alternative tool for estimating credibility.

  17. Aerodynamics: The Wright Way

    NASA Technical Reports Server (NTRS)

    Cole, Jennifer Hansen

    2010-01-01

    This slide presentation reviews some of the basic principles of aerodynamics. Included in the presentation are: a few demonstrations of the principles, an explanation of the concepts of lift, drag, thrust and weight, a description of Bernoulli's principle, the concept of the airfoil (i.e., the shape of the wing) and how that effects lift, and the method of controlling an aircraft by manipulating the four forces using control surfaces.

  18. Cosmology, Clusters and Calorimeters

    NASA Technical Reports Server (NTRS)

    Figueroa-Feliciano, Enectali

    2005-01-01

    I will review the current state of Cosmology with Clusters and discuss the application of microcalorimeter arrays to this field. With the launch of Astro-E2 this summer and a slew of new missions being developed, microcalorimeters are the next big thing in x-ray astronomy. I will cover the basics and not-so-basic concepts of microcalorimeter designs and look at the future to see where this technology will go.

  19. Developmental Neurotoxicology: History and Outline of Developmental Neurotoxicity Study Guidelines.

    EPA Science Inventory

    The present work provides a brief review of basic concepts in developmental neurotoxicology, as well as current representative testing guidelines for evaluating developmental neurotoxicity (DNT) of xenobiotics. Historically, DNT was initially recognized as a “functional” teratoge...

  20. Endoradiotherapy in cancer treatment--basic concepts and future trends.

    PubMed

    Zoller, Frederic; Eisenhut, Michael; Haberkorn, Uwe; Mier, Walter

    2009-12-25

    Endoradiotherapy represents an alternative therapeutic method in cancer treatment with advantageous features compared to chemotherapy and radiation therapy. Intelligent dose delivery concepts using small drugs, peptides or antibodies as radionuclide carriers enable the verification of a selective accumulation in the tumour lesion and to reduce radiation toxicity for the peripheral organs. The development of endoradiotherapeutic agents, especially chelator-conjugated biomolecules, for example ibritumomab tiuxetan or DOTATOC, gains importance due to the stable complexation of versatile radiometals, such as (90)Y or (177)Lu. The rational design of novel target binding sides and their grafting into a drug scaffold is a highly promising strategy, which may promote further implication in endoradiotherapy. This review highlights the basic concepts of endoradiotherapy and discusses the potential of targeted therapy and the properties of energy-rich particles emitted by radionuclides for tumour therapy.

  1. Engine design considerations for 2nd generation supersonic transports

    NASA Technical Reports Server (NTRS)

    Howlett, R. A.

    1975-01-01

    The environmental and economic goals projected for advanced supersonic transports will require revolutionary improvements in propulsion systems. Variable cycle engine concepts that incorporate unique components and advanced technologies show promise in meeting these goals. Pratt & Whitney Aircraft is conducting conceptual design studies of variable cycle engine concepts under NASA sponsorship. This paper reviews some of the design considerations for these engine concepts. Emphasis is placed on jet noise abatement, reduction of emissions, performance improvements, installation considerations, hot-section characteristics and control system requirements. Two representative variable cycle engine concepts that incorporate these basic design considerations are described.

  2. Basic Combat Unit of the Slovenian Armed Forces

    DTIC Science & Technology

    2017-06-09

    research offers a review of relevant Slovenian strategic documents, a combined arms concept and the last major U.S. Army transformation that saw the...Armed forces should be. Findings, with other recommendations, should be the foundation for the upcoming transformation of the Slovenian Armed...arms concept and the last major U.S. Army transformation that saw the organization transition from a division to a brigade-centric force. The goal

  3. Navy Space and Astronautics Orientation.

    ERIC Educational Resources Information Center

    Herron, R. G.

    Fundamental concepts of the spatial environment, technologies, and applications are presented in this manual prepared for senior officers and key civilian employees. Following basic information on the atmosphere, solar system, and intergalactic space, a detailed review is included of astrodynamics, rocket propulsion, bioastronautics, auxiliary…

  4. Nuclear pharmacy: An introduction to the clinical application of radiopharmaceuticals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chilton, H.M.; Witcofski, R.L.

    1986-01-01

    This introductory text reviews fundamental concepts of nuclear pharmacy in a logical, stepwise manner. It presents those aspects of radioactivity basic to nuclear pharmacy including production of radioactivity and the types of instrumentation used to detect and measure radiation.

  5. High Speed Rail Tilt Train Technology : A State of the Art Survey

    DOT National Transportation Integrated Search

    1992-06-01

    This report presents an assessment of the technical and operational features of existing and proposed tilt-body rail passenger vehicles. Basic concepts of railroad route selection, track geometry, and curve negotiation are reviewed, and the rationale...

  6. Microfluidic tools for cell biological research

    PubMed Central

    Velve-Casquillas, Guilhem; Le Berre, Maël; Piel, Matthieu; Tran, Phong T.

    2010-01-01

    Summary Microfluidic technology is creating powerful tools for cell biologists to control the complete cellular microenvironment, leading to new questions and new discoveries. We review here the basic concepts and methodologies in designing microfluidic devices, and their diverse cell biological applications. PMID:21152269

  7. Briefing: Microprocessors.

    ERIC Educational Resources Information Center

    Standing, Roy A.

    1982-01-01

    Reviews the basic concepts and technology behind the functions computers perform, describes the miniaturization of computer components, discusses the development of the microprocessor and the microcomputer, and makes projections concerning the future of the microcomputer market. Information is provided on the features, costs, and manufacturers of…

  8. Fundamentals of neurogastroenterology: basic science.

    PubMed

    Grundy, David; Al-Chaer, Elie D; Aziz, Qasim; Collins, Stephen M; Ke, Meiyun; Taché, Yvette; Wood, Jackie D

    2006-04-01

    The focus of neurogastroenterology in Rome II was the enteric nervous system (ENS). To avoid duplication with Rome II, only advances in ENS neurobiology after Rome II are reviewed together with stronger emphasis on interactions of the brain, spinal cord, and the gut in terms of relevance for abdominal pain and disordered gastrointestinal function. A committee with expertise in selective aspects of neurogastroenterology was invited to evaluate the literature and provide a consensus overview of the Fundamentals of Neurogastroenterology textbook as they relate to functional gastrointestinal disorders (FGIDs). This review is an abbreviated version of a fuller account that appears in the forthcoming book, Rome III. This report reviews current basic science understanding of visceral sensation and its modulation by inflammation and stress and advances in the neurophysiology of the ENS. Many of the concepts are derived from animal studies in which the physiologic mechanisms underlying visceral sensitivity and neural control of motility, secretion, and blood flow are examined. Impact of inflammation and stress in experimental models relative to FGIDs is reviewed as is human brain imaging, which provides a means for translating basic science to understanding FGID symptoms. Investigative evidence and emerging concepts implicate dysfunction in the nervous system as a significant factor underlying patient symptoms in FGIDs. Continued focus on neurogastroenterologic factors that underlie the development of symptoms will lead to mechanistic understanding that is expected to directly benefit the large contingent of patients and care-givers who deal with FGIDs.

  9. A basic introduction to statistics for the orthopaedic surgeon.

    PubMed

    Bertrand, Catherine; Van Riet, Roger; Verstreken, Frederik; Michielsen, Jef

    2012-02-01

    Orthopaedic surgeons should review the orthopaedic literature in order to keep pace with the latest insights and practices. A good understanding of basic statistical principles is of crucial importance to the ability to read articles critically, to interpret results and to arrive at correct conclusions. This paper explains some of the key concepts in statistics, including hypothesis testing, Type I and Type II errors, testing of normality, sample size and p values.

  10. Review of key concepts in magnetic resonance physics.

    PubMed

    Moore, Michael M; Chung, Taylor

    2017-05-01

    MR physics can be a challenging subject for practicing pediatric radiologists. Although many excellent texts provide very comprehensive reviews of the field of MR physics at various levels of understanding, the authors of this paper explain several key concepts in MR physics that are germane to clinical practice in a non-rigorous but practical fashion. With the basic understanding of these key concepts, practicing pediatric radiologists can build on their knowledge of current clinical MR techniques and future advances in MR applications. Given the challenges of both the increased need for rapid imaging in non-sedated children and the rapid physiological cardiovascular and respiratory motion in pediatric patients, many advances in complex MR techniques are being applied to imaging these children. The key concepts are as follows: (1) structure of a pulse sequence, (2) k-space, (3) "trade-off triangle" and (4) fat suppression. This review is the first of five manuscripts in a minisymposium on pediatric MR. The authors' goal for this review is to aid in understanding the MR techniques described in the subsequent manuscripts on brain imaging and body imaging in this minisymposium.

  11. Strategic planning for national security: Lessons from business experience. Interim report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bracken, P.

    1990-02-01

    United States defense planning is at a crossroads and it is therefore useful to review not only discrete issues, but even basic concepts of strategic planning. This Note reviews concepts used in the business world to build insights about how to view current and prospective problems, opportunities, and choices. The author draws upon the business literature for both ideas and metaphors. He observes that U.S. national security planning could profit greatly from an approach that distinguishes among core, environmental, and hedging strategies, and that considers security analogs to such business concepts as defining the business, dealing with new competitors, controllingmore » the intensity of competition, entry and exit barriers, and the need to redeploy assets and restructure the organization. He then relates these concepts to specific problems of national security interest.« less

  12. The articulation of integration of clinical and basic sciences in concept maps: differences between experienced and resident groups.

    PubMed

    Vink, Sylvia; van Tartwijk, Jan; Verloop, Nico; Gosselink, Manon; Driessen, Erik; Bolk, Jan

    2016-08-01

    To determine the content of integrated curricula, clinical concepts and the underlying basic science concepts need to be made explicit. Preconstructed concept maps are recommended for this purpose. They are mainly constructed by experts. However, concept maps constructed by residents are hypothesized to be less complex, to reveal more tacit basic science concepts and these basic science concepts are expected to be used for the organization of the maps. These hypotheses are derived from studies about knowledge development of individuals. However, integrated curricula require a high degree of cooperation between clinicians and basic scientists. This study examined whether there are consistent variations regarding the articulation of integration when groups of experienced clinicians and basic scientists and groups of residents and basic scientists-in-training construct concept maps. Seven groups of three clinicians and basic scientists on experienced level and seven such groups on resident level constructed concept maps illuminating clinical problems. They were guided by instructions that focused them on articulation of integration. The concept maps were analysed by features that described integration. Descriptive statistics showed consistent variations between the two expertise levels. The concept maps of the resident groups exceeded those of the experienced groups in articulated integration. First, they used significantly more links between clinical and basic science concepts. Second, these links connected basic science concepts with a greater variety of clinical concepts than the experienced groups. Third, although residents did not use significantly more basic science concepts, they used them significantly more frequent to organize the clinical concepts. The conclusion was drawn that not all hypotheses could be confirmed and that the resident concept maps were more elaborate than expected. This article discusses the implications for the role that residents and basic scientists-in-training might play in the construction of preconstructed concept maps and the development of integrated curricula.

  13. Basic principles of test-negative design in evaluating influenza vaccine effectiveness.

    PubMed

    Fukushima, Wakaba; Hirota, Yoshio

    2017-08-24

    Based on the unique characteristics of influenza, the concept of "monitoring" influenza vaccine effectiveness (VE) across the seasons using the same observational study design has been developed. In recent years, there has been a growing number of influenza VE reports using the test-negative design, which can minimize both misclassification of diseases and confounding by health care-seeking behavior. Although the test-negative designs offer considerable advantages, there are some concerns that widespread use of the test-negative design without knowledge of the basic principles of epidemiology could produce invalid findings. In this article, we briefly review the basic concepts of the test-negative design with respect to classic study design such as cohort studies or case-control studies. We also mention selection bias, which may be of concern in some countries where rapid diagnostic testing is frequently used in routine clinical practices, as in Japan. Copyright © 2017. Published by Elsevier Ltd.

  14. Design review report for rotary mode core sample truck (RMCST) modifications for flammable gas tanks, preliminary design

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Corbett, J.E.

    1996-02-01

    This report documents the completion of a preliminary design review for the Rotary Mode Core Sample Truck (RMCST) modifications for flammable gas tanks. The RMCST modifications are intended to support core sampling operations in waste tanks requiring flammable gas controls. The objective of this review was to validate basic design assumptions and concepts to support a path forward leading to a final design. The conclusion reached by the review committee was that the design was acceptable and efforts should continue toward a final design review.

  15. The Review on the Charge Distribution on the Conductor Surface

    ERIC Educational Resources Information Center

    Matehkolaee, M. Jafari; Asrami, A. Naderi

    2013-01-01

    In this paper we have a full review on the surface charge density at disordered conductor surfaces. Basically, reading text books does not resolve ambiguities in this field. As far as is possible, we have tried to the concepts easier to turn. In fact we will answer two questions. One of them is that why do charges tend to go where the curvature is…

  16. A brain-based account of “basic-level” concepts

    PubMed Central

    Bauer, Andrew James; Just, Marcel Adam

    2017-01-01

    This study provides a brain-based account of how object concepts at an intermediate (basic) level of specificity are represented, offering an enriched view of what it means for a concept to be a basic-level concept, a research topic pioneered by Rosch and others (Rosch et al., 1976). Applying machine learning techniques to fMRI data, it was possible to determine the semantic content encoded in the neural representations of object concepts at basic and subordinate levels of abstraction. The representation of basic-level concepts (e.g. bird) was spatially broad, encompassing sensorimotor brain areas that encode concrete object properties, and also language and heteromodal integrative areas that encode abstract semantic content. The representation of subordinate-level concepts (robin) was less widely distributed, concentrated in perceptual areas that underlie concrete content. Furthermore, basic-level concepts were representative of their subordinates in that they were neurally similar to their typical but not atypical subordinates (bird was neurally similar to robin but not woodpecker). The findings provide a brain-based account of the advantages that basic-level concepts enjoy in everyday life over subordinate-level concepts: the basic level is a broad topographical representation that encompasses both concrete and abstract semantic content, reflecting the multifaceted yet intuitive meaning of basic-level concepts. PMID:28826947

  17. A brain-based account of "basic-level" concepts.

    PubMed

    Bauer, Andrew James; Just, Marcel Adam

    2017-11-01

    This study provides a brain-based account of how object concepts at an intermediate (basic) level of specificity are represented, offering an enriched view of what it means for a concept to be a basic-level concept, a research topic pioneered by Rosch and others (Rosch et al., 1976). Applying machine learning techniques to fMRI data, it was possible to determine the semantic content encoded in the neural representations of object concepts at basic and subordinate levels of abstraction. The representation of basic-level concepts (e.g. bird) was spatially broad, encompassing sensorimotor brain areas that encode concrete object properties, and also language and heteromodal integrative areas that encode abstract semantic content. The representation of subordinate-level concepts (robin) was less widely distributed, concentrated in perceptual areas that underlie concrete content. Furthermore, basic-level concepts were representative of their subordinates in that they were neurally similar to their typical but not atypical subordinates (bird was neurally similar to robin but not woodpecker). The findings provide a brain-based account of the advantages that basic-level concepts enjoy in everyday life over subordinate-level concepts: the basic level is a broad topographical representation that encompasses both concrete and abstract semantic content, reflecting the multifaceted yet intuitive meaning of basic-level concepts. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Marketing II Workbook.

    ERIC Educational Resources Information Center

    Reeves, Cheryl

    This combination curriculum and workbook, which was originally developed for use in a training workshop, is intended to assist adult educators in learning to market their adult literacy programs. The first chapter reviews basic marketing concepts (the definition of marketing, 10 truths about marketing, marketing versus promotion, steps in…

  19. TRANSPORTATION LONG AGO.

    ERIC Educational Resources Information Center

    George Washington Univ., Washington, DC.

    THIS HISTORICAL REVIEW OF TRANSPORTATION REPRESENTS AN EXPERIMENTAL BOOKLET OF ILLUSTRATIONS AND SINGLE TEXT FOR USE BY TEACHERS TO STIMULATE INTEREST IN READING AND IN RELATED MECHANICAL SUBJECT MATTER AREAS. IT AIMS TO HELP YOUNG PEOPLE LEARN BASIC PRINCIPLES AND CONCEPTS OF MECHANICS AND TECHNOLOGY. PHOTOGRAPHS AND ILLUSTRATIONS, SELECTED FROM…

  20. Teaching Sustainability to Business Students: Shifting Mindsets

    ERIC Educational Resources Information Center

    Stubbs, Wendy; Cocklin, Chris

    2008-01-01

    Purpose: This paper seeks to describe a framework used to help MBA students understand and reconcile the different sustainability perspectives. Design/methodology/approach: A review of the corporate sustainability literature is undertaken to develop the sustainability framework. Findings: The sustainability framework relates basic concepts and…

  1. Installing a Practical Research Project and Interpreting Research Results

    Treesearch

    Kasten R. Dumroese; David L. Wenny

    2003-01-01

    The basic concepts of the scientific method and research process are reviewed. An example from a bareroot nursery demonstrates how a practical research project can be done at any type of nursery, meshing sound statistical principles with the limitations of busy nursery managers.

  2. Computer Training for Staff and Patrons.

    ERIC Educational Resources Information Center

    Krissoff, Alan; Konrad, Lee

    1998-01-01

    Describes a pilot computer training program for library staff and patrons at the University of Wisconsin-Madison. Reviews components of effective training programs and highlights core computer competencies: operating systems, hardware and software basics and troubleshooting, and search concepts and techniques. Includes an instructional outline and…

  3. Crisis Counseling: An Overview

    ERIC Educational Resources Information Center

    Sandoval, Jonathan; Scott, Amy Nicole; Padilla, Irene

    2009-01-01

    Psychologists working in schools are often the first contacts for children experiencing a potentially traumatizing event or change in status. This article reviews basic concepts in crisis counseling and describes the components of psychological first aid. This form of counseling must be developmentally and culturally appropriate as well as…

  4. Attitudes, Administrative Styles, and Outcomes.

    ERIC Educational Resources Information Center

    Laughlin, J. Stanley

    1984-01-01

    The literature on administrative style is reviewed. Attention is directed to four basic concepts of administrative style: (1) the structured, classical, traditional model; (2) the participatory or employee-involved operation; (3) a more behavioral scientific style; and (4) the situational or environmental style. These ideas are more fully…

  5. Radiation Chemistry in Organized Assemblies.

    ERIC Educational Resources Information Center

    Thomas, J. K.; Chen, T. S.

    1981-01-01

    Expands the basic concepts regarding the radiation chemistry of simple aqueous systems to more complex, but well defined, organized assemblies. Discusses the differences in behavior in comparison to simple systems. Reviews these techniques: pulse radiolysis, laser flash, photolysis, and steady state irradiation by gamma rays or light. (CS)

  6. [A review on urban metabolism research based on physical space entities for environmental management].

    PubMed

    Liu, Ye; Liu, Dan

    2015-07-01

    Urban metabolism is a basic theory for coping with global environmental problems, which is coherent with the aims of national environmental management. This paper analyzed the concept of urban metabolism, and pointed out the meaning for urban metabolism in physical space entities; reviewed the current methods for urban metabolism and its merits and shortages; analyzed the system boundaries, connotation, and methodologies; and summarized the advances on urban meta-bolism practices in physical space entities. At last, we made conclusions that there were shortages, including conception system, basic theory system, and interdisciplinary integrated theory system in current urban metabolism research, and the current cases studied in urban metabolism were limited and not suitable to the harmony development between society, economy, and environment. In the future, we need to strengthen comparison between different case studies from different countries, develop the prior modes of typical urban metabolism research, identify the mechanism for urban ecosystem, and strengthen the spatial decision support system of environmental management taking urban spatial entity spaces as units.

  7. New concepts in the assessment and treatment of regional musculoskeletal pain and sports injury.

    PubMed

    Borg-Stein, Joanne; Zaremski, Jason L; Hanford, Mary Alice

    2009-08-01

    During the past decade there have been significant advances in understanding the basic science of musculoskeletal injury and healing. These new concepts alter the approach to injury management and rehabilitation for clinicians managing musculoskeletal conditions. This article examines the most recent advances in the treatment of regional musculoskeletal pain, and muscle and tendon sports injury. Specifically, developments in understanding the pathogenesis of muscle and tendon sports injuries, newer imaging modalities, and updated treatment paradigms and their rationale are reviewed. The purpose of this review is to provide the clinician with new approaches for treating nonsurgical muscle and tendon injuries.

  8. Conceptual and methodological concerns in the theory of perceptual load.

    PubMed

    Benoni, Hanna; Tsal, Yehoshua

    2013-01-01

    The present paper provides a short critical review of the theory of perceptual load. It closely examines the basic tenets and assumptions of the theory and identifies major conceptual and methodological problems that have been largely ignored in the literature. The discussion focuses on problems in the definition of the concept of perceptual load, on the circularity in the characterization and manipulation of perceptual load and the confusion between the concept of perceptual load and its operationalization. The paper also selectively reviews evidence supporting the theory as well as inconsistent evidence which proposed alternative dominant factors influencing the efficacy of attentional selection.

  9. Conceptual and methodological concerns in the theory of perceptual load

    PubMed Central

    Benoni, Hanna; Tsal, Yehoshua

    2013-01-01

    The present paper provides a short critical review of the theory of perceptual load. It closely examines the basic tenets and assumptions of the theory and identifies major conceptual and methodological problems that have been largely ignored in the literature. The discussion focuses on problems in the definition of the concept of perceptual load, on the circularity in the characterization and manipulation of perceptual load and the confusion between the concept of perceptual load and its operationalization. The paper also selectively reviews evidence supporting the theory as well as inconsistent evidence which proposed alternative dominant factors influencing the efficacy of attentional selection. PMID:23964262

  10. CNS development: an overview

    NASA Technical Reports Server (NTRS)

    Nowakowski, R. S.; Hayes, N. L.

    1999-01-01

    The basic principles of the development of the central nervous system (CNS) are reviewed, and their implications for both normal and abnormal development of the brain are discussed. The goals of this review are (a) to provide a set of concepts to aid in understanding the variety of complex processes that occur during CNS development, (b) to illustrate how these concepts contribute to our knowledge of the normal anatomy of the adult brain, and (c) to provide a basis for understanding how modifications of normal developmental processes by traumatic injury, by environmental or experiential influences, or by genetic variations may lead to modifications in the resultant structure and function of the adult CNS.

  11. Demasking Wall Street's Influence on Stock Prices.

    ERIC Educational Resources Information Center

    Saban, Kenneth A.

    1987-01-01

    Presents an in-depth review of the market research approach of a comprehensive financial community. Discusses the applied corporate findings when author was Vice President, Corporate Communications, Midland-Ross Corporation. Suggests that the basic concept is applicable to any publicly traded company whose senior management desires a more…

  12. The Chemistry of Fitness. Active Activities.

    ERIC Educational Resources Information Center

    Bergandine, David R.; And Others

    1991-01-01

    The outline for a unit on the chemistry of fitness and nutrition is presented. Topics discussed include the organic basis of life, functional groups, kitchen experiments, micronutrients, energetics, fitness vs. fatness, current topics, and evaluation. This unit reviews the basic concepts of chemical bonding, acid-base chemistry, stoichiometry, and…

  13. Installing a practical research project and interpreting research results

    Treesearch

    R. Kasten Dumroese; David L. Weny

    2002-01-01

    We review the basic concepts of science and research and the scientific process. Using an example from a bareroot nursery, we show how a practical research project can be done at any type of nursery, meshing sound statistical principles with limitations of busy nursery managers.

  14. Employer-Sponsored Career Development Programs. Information Series No. 231.

    ERIC Educational Resources Information Center

    Lancaster, Anita Sklare; Berne, Richard R.

    This monograph presents an overview of employer-sponsored career development programs. It is divided into four sections. The "Adult Development" and "Adult Career Development" sections review pertinent theories and research (basic concepts, task model, transition model, theme model, adult career stages, career anchors approach, career development…

  15. Self-Determination Theory: Intrinsic Motivation and Behavioral Change.

    PubMed

    Flannery, Marie

    2017-03-01

    Motivation is a central concept in behavioral change. This article reviews the self-determination theory with an emphasis on "intrinsic motivation," which is facilitated when three basic psychological needs (autonomy, competence, and relatedness) are met. Intrinsic motivation is associated with improved well-being and sustained behavioral change.

  16. Cash Management/Data Matching. Training Guide.

    ERIC Educational Resources Information Center

    Office of Student Financial Assistance (ED), Washington, DC.

    This training guide for financial aid staff explains the process of direct loan reconciliation and suggests appropriate cash management accounting practices. Chapter 1 explains the importance of cash management, the role of data matching, and reviews basic reconciliation concepts and terms and direct loan reporting requirements. Chapter 2 reviews…

  17. The use of solution adaptive grids in solving partial differential equations

    NASA Technical Reports Server (NTRS)

    Anderson, D. A.; Rai, M. M.

    1982-01-01

    The grid point distribution used in solving a partial differential equation using a numerical method has a substantial influence on the quality of the solution. An adaptive grid which adjusts as the solution changes provides the best results when the number of grid points available for use during the calculation is fixed. Basic concepts used in generating and applying adaptive grids are reviewed in this paper, and examples illustrating applications of these concepts are presented.

  18. Particulate Matter Filtration Design Considerations for Crewed Spacecraft Life Support Systems

    NASA Technical Reports Server (NTRS)

    Agui, Juan H.; Vijayakumar, R.; Perry, Jay L.

    2016-01-01

    Particulate matter filtration is a key component of crewed spacecraft cabin ventilation and life support system (LSS) architectures. The basic particulate matter filtration functional requirements as they relate to an exploration vehicle LSS architecture are presented. Particulate matter filtration concepts are reviewed and design considerations are discussed. A concept for a particulate matter filtration architecture suitable for exploration missions is presented. The conceptual architecture considers the results from developmental work and incorporates best practice design considerations.

  19. Process control systems at Homer City coal preparation plant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shell, W.P.

    1983-03-01

    An important part of process control engineering is the implementation of the basic control system design through commissioning to routine operation. This is a period when basic concepts can be reviewed and improvements either implemented or recorded for application in future systems. The experience of commissioning the process control systems in the Homer City coal cleaning plant are described and discussed. The current level of operating control performance in individual sections and the overall system are also reported and discussed.

  20. Problem solving and decisionmaking: An integration

    NASA Technical Reports Server (NTRS)

    Dieterly, D. L.

    1980-01-01

    An attempt was made to redress a critical fault of decisionmaking and problem solving research-a lack of a standard method to classify problem or decision states or conditions. A basic model was identified and expanded to indicate a possible taxonomy of conditions which may be used in reviewing previous research or for systematically pursuing new research designs. A generalization of the basic conditions was then made to indicate that the conditions are essentially the same for both concepts, problem solving and decisionmaking.

  1. MHD processes in the outer heliosphere

    NASA Technical Reports Server (NTRS)

    Burlaga, L. F.

    1984-01-01

    The magnetic field measurements from Voyager and the magnetohydrodynamic (MHD) processes in the outer heliosphere are reviewed. A bibliography of the experimental and theoretical work concerning magnetic fields and plasmas observed in the outer heliosphere is given. Emphasis in this review is on basic concepts and dynamical processes involving the magnetic field. The theory that serves to explain and unify the interplanetary magnetic field and plasma observations is magnetohydrodynamics. Basic physical processes and observations that relate directly to solutions of the MHD equations are emphasized, but obtaining solutions of this complex system of equations involves various assumptions and approximations. The spatial and temporal complexity of the outer heliosphere and some approaches for dealing with this complexity are discussed.

  2. Basic symptoms and the prediction of first-episode psychosis.

    PubMed

    Schultze-Lutter, Frauke; Ruhrmann, Stephan; Fusar-Poli, Paolo; Bechdolf, Andreas; Schimmelmann, Benno G; Klosterkötter, Joachim

    2012-01-01

    Recent focus on early detection and intervention in psychosis has renewed interest in subtle psychopathology beyond positive and negative symptoms. Such self-experienced sub-clinical disturbances are described in detail by the basic symptom concept. This review will give an introduction into the concept of basic symptoms and describe the development of the current instruments for their assessment, the Schizophrenia Proneness Instrument, Adult (SPI-A) and Child and Youth version (SPI-CY), as well as of the two at-risk criteria: the at-risk criterion Cognitive-Perceptive Basic Symptoms (COPER) and the high-risk criterion Cognitive Disturbances (COGDIS). Further, an overview of prospective studies using both or either basic symptom criteria and transition rates related to these will be given, and the potential benefit of combining ultra-high risk criteria, particularly attenuated psychotic symptoms, and basic symptom criteria will be discussed. Finally, their prevalence in psychosis patients, i.e. the sensitivity, as well as in general population samples will be described. It is concluded that both COPER and COGDIS are able to identify subjects at a high risk of developing psychosis. Further, they appear to be sufficiently frequent prior to onset of the first psychotic episode as well as sufficiently rare in persons of general population to be considered as valuable for an early detection of psychosis.

  3. Theoretical Methods of Domain Structures in Ultrathin Ferroelectric Films: A Review

    PubMed Central

    Liu, Jianyi; Chen, Weijin; Wang, Biao; Zheng, Yue

    2014-01-01

    This review covers methods and recent developments of the theoretical study of domain structures in ultrathin ferroelectric films. The review begins with an introduction to some basic concepts and theories (e.g., polarization and its modern theory, ferroelectric phase transition, domain formation, and finite size effects, etc.) that are relevant to the study of domain structures in ultrathin ferroelectric films. Basic techniques and recent progress of a variety of important approaches for domain structure simulation, including first-principles calculation, molecular dynamics, Monte Carlo simulation, effective Hamiltonian approach and phase field modeling, as well as multiscale simulation are then elaborated. For each approach, its important features and relative merits over other approaches for modeling domain structures in ultrathin ferroelectric films are discussed. Finally, we review recent theoretical studies on some important issues of domain structures in ultrathin ferroelectric films, with an emphasis on the effects of interfacial electrostatics, boundary conditions and external loads. PMID:28788198

  4. Vygotskian Tradition in the Psychological Study of Handicapped, Particularly Deaf Children.

    ERIC Educational Resources Information Center

    Knox, Jane; Kozulin, Alex

    The paper reviews theories of Lev Vygotsky, founder of the Soviet school of cognitive developmental psychology and an architect of Soviet defectology, the discipline concerned with physically and mentally handicapped children. Three of his basic concepts are explained: (1) "cultural" versus "natural" mental functions; (2)…

  5. Analysis and Interpretation of Findings Using Multiple Regression Techniques

    ERIC Educational Resources Information Center

    Hoyt, William T.; Leierer, Stephen; Millington, Michael J.

    2006-01-01

    Multiple regression and correlation (MRC) methods form a flexible family of statistical techniques that can address a wide variety of different types of research questions of interest to rehabilitation professionals. In this article, we review basic concepts and terms, with an emphasis on interpretation of findings relevant to research questions…

  6. Math Interventions for Students with Autism Spectrum Disorder: A Best-Evidence Synthesis

    ERIC Educational Resources Information Center

    King, Seth A.; Lemons, Christopher J.; Davidson, Kimberly A.

    2016-01-01

    Educators need evidence-based practices to assist students with disabilities in meeting increasingly rigorous standards in mathematics. Students with autism spectrum disorder (ASD) are increasingly expected to demonstrate learning of basic and advanced mathematical concepts. This review identifies math intervention studies involving children and…

  7. Arms Control and National Security: An Introduction. Advance Edition.

    ERIC Educational Resources Information Center

    Arms Control Association, Washington, DC.

    Suitable for use with high school students, this booklet on arms control and national security provides background information, describes basic concepts, reviews recent history, and offers suggestions for further reading. The first section, on American attitudes toward national security and arms control, defines five types of limits on weapons…

  8. Emergent Literacy: Learning about Print before Learning to Read.

    ERIC Educational Resources Information Center

    van Kleeck, Anne

    1990-01-01

    This article reviews the literature regarding the seeds of literacy in preschool students. Conclusions indicate that children learn many basic concepts of print communication from daily experience with its use well before any ability to decode writing emerges. Games and other everyday interactions with print are recommended for facilitating…

  9. YouTube as a Qualitative Research Asset: Reviewing User Generated Videos as Learning Resources

    ERIC Educational Resources Information Center

    Chenail, Ronald J.

    2011-01-01

    YouTube, the video hosting service, offers students, teachers, and practitioners of qualitative researchers a unique reservoir of video clips introducing basic qualitative research concepts, sharing qualitative data from interviews and field observations, and presenting completed research studies. This web-based site also affords qualitative…

  10. An Effective Time and Management Strategy in Quality Circles.

    ERIC Educational Resources Information Center

    Halverson, Don E.

    Contending that participation in quality circles enhances effective time management by school administrators and teachers, this guide provides both a theoretical briefing and practical recommendations for better time management. A pre- posttest prefaces a review of basic concepts of quality circles with reference to the work of Abraham Maslow,…

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kalousek, D.K.; Fitch, N.; Paradice, B.

    Topics covered in this book include a general review of normal embryonic and fetal development; abortion and the basic approach to the examination of aborted embryos and fetuses; and pathologic findings detected on examination of products of conception. The authors illustrate specific morphologic lesions and the variable expression of genetic syndromes in the embryonic and fetal periods.

  12. Student Activity Guide for "Business in an Information Economy."

    ERIC Educational Resources Information Center

    Graf, David; And Others

    The 20 chapters of this student activity guide provide study guides (key terms and concepts reviews), projects, cases for analyses, and self-assessment exercises for business and career education classes. Topics covered include the following: business winners (entrepreneurship); growth of the U.S. economy, the basics of economics, comparing…

  13. Moral Development in Higher Education

    ERIC Educational Resources Information Center

    Liddell, Debora L.; Cooper, Diane L.

    2012-01-01

    In this article, the authors lay out the basic foundational concepts and assumptions that will guide the reader through the chapters to come as the chapter authors explore "how" moral growth can be facilitated through various initiatives on the college campus. This article presents a brief review of the theoretical frameworks that provide the…

  14. Handbook of Communication.

    ERIC Educational Resources Information Center

    Pool, Ithiel de Sola, Ed.; And Others

    Each of the 31 chapters which comprise this volume reviews the state of the art in a specific area of communications research. The chapters are grouped into three sections, the first of which focuses upon the basic communication process. An introduction to the concept of a communication system and to the phenomena of language and nonverbal…

  15. Silvicultural options for neotropical migratory birds

    Treesearch

    Frank R. Thompson; John R. Probst; Martin G. Raphael

    1993-01-01

    We review: factors that affect forest bird populations; basic concepts of silvicultural systems; potential impacts of these systems on neotropical migratory birds (NTMBs); and conclude with management recommendations for integrating NTMB conservation with forest management. We approach this topic from a regional-landscape scale to a forest stand-habitat scale, rather...

  16. Technological Augmentation of Human Cognition: An Interdisciplinary Review.

    ERIC Educational Resources Information Center

    Smithsonian Institution, Washington, DC.

    A series of five interdisciplinary conferences held over a two-year period explored new teaching and training concepts and methodologies which offer powerful, symbiotic means of augmenting human cognition. The basic discussion points of the conferences are summarized. It was felt that the conferences were significant in that they brought together…

  17. Solar Program Assessment: Environmental Factors - Fuels from Biomass.

    ERIC Educational Resources Information Center

    Energy Research and Development Administration, Washington, DC. Div. of Solar Energy.

    The purpose of this report is to present and prioritize the major environmental issues associated with the further development of biomass production and biomass conversion systems. To provide a background for this environmental analysis, the basic concepts of the technology are reviewed, as are resource requirements. The potential effects of this…

  18. Strategic Planning Techniques: Matching External Assessment with Internal Audit.

    ERIC Educational Resources Information Center

    Groff, Warren H.

    The literature on strategic planning, and the capabilities of Massachusetts system of public postsecondary education were assessed, as part of a 1981 leadership seminar. Teams from all public postsecondary education institutions in the state reviewed the basic concepts of strategic planning; critically analyzed the environment external to their…

  19. Clarifying Prescriptive Messages about HIV: The Case of Long-Term Mutually Monogamous Relationships.

    ERIC Educational Resources Information Center

    Parrillo, Anthony V.; Clark, Jeffrey K.

    1995-01-01

    Examines the appropriateness of using the word monogamy in acquired immune deficiency syndrome (AIDS) education, identifying basic concepts within prescriptive messages about human immunodeficiency virus (HIV); reviewing definitions, applications, and interpretations of monogamy in the literature; presenting a content analysis of sexuality and…

  20. TOPICAL REVIEW: Electric current activated/assisted sintering (ECAS): a review of patents 1906-2008

    NASA Astrophysics Data System (ADS)

    Grasso, Salvatore; Sakka, Yoshio; Maizza, Giovanni

    2009-10-01

    The electric current activated/assisted sintering (ECAS) is an ever growing class of versatile techniques for sintering particulate materials. Despite the tremendous advances over the last two decades in ECASed materials and products there is a lack of comprehensive reviews on ECAS apparatuses and methods. This paper fills the gap by tracing the progress of ECAS technology from 1906 to 2008 and surveys 642 ECAS patents published over more than a century. It is found that the ECAS technology was pioneered by Bloxam (1906 GB Patent No. 9020) who developed the first resistive sintering apparatus. The patents were searched by keywords or by cross-links and were withdrawn from the Japanese Patent Office (342 patents), the United States Patent and Trademark Office (175 patents), the Chinese State Intellectual Property Office of P.R.C. (69 patents) and the World Intellectual Property Organization (12 patents). A subset of 119 (out of 642) ECAS patents on methods and apparatuses was selected and described in detail with respect to their fundamental concepts, physical principles and importance in either present ECAS apparatuses or future ECAS technologies for enhancing efficiency, reliability, repeatability, controllability and productivity. The paper is divided into two parts, the first deals with the basic concepts, features and definitions of basic ECAS and the second analyzes the auxiliary devices/peripherals. The basic ECAS is classified with reference to discharge time (fast and ultrafast ECAS). The fundamental principles and definitions of ECAS are outlined in accordance with the scientific and patent literature.

  1. Molecular Phylogenetics: Concepts for a Newcomer.

    PubMed

    Ajawatanawong, Pravech

    Molecular phylogenetics is the study of evolutionary relationships among organisms using molecular sequence data. The aim of this review is to introduce the important terminology and general concepts of tree reconstruction to biologists who lack a strong background in the field of molecular evolution. Some modern phylogenetic programs are easy to use because of their user-friendly interfaces, but understanding the phylogenetic algorithms and substitution models, which are based on advanced statistics, is still important for the analysis and interpretation without a guide. Briefly, there are five general steps in carrying out a phylogenetic analysis: (1) sequence data preparation, (2) sequence alignment, (3) choosing a phylogenetic reconstruction method, (4) identification of the best tree, and (5) evaluating the tree. Concepts in this review enable biologists to grasp the basic ideas behind phylogenetic analysis and also help provide a sound basis for discussions with expert phylogeneticists.

  2. Basic physics of nuclear magnetic resonance.

    PubMed

    Patz, S

    1986-01-01

    This review of basic physics of nuclear magnetic resonance (NMR) discusses precession of magnetic nuclei in a static external field, introduces the concept of the rotating frame, and describes excitation of nuclei by an RF field. Treats subject of T1 and T2 relaxation from the dual viewpoints of (1) phenomena of relaxation times for both the longitudinal and transverse magnetization and (2) relaxation resulting from local field fluctuations. It describes practical ways in which T1 and T2 are measured (i.e., inversion recovery and spin-echo) and gives the value of the nuclear magnetization in thermodynamic equilibrium with a static external field. It discusses the reduction of NMR signal resulting from saturation. These concepts are related to clinical use with a set of four spin-echo images of a human head.

  3. A review of basic patient rights in psychiatric care.

    PubMed

    Cady, Rebecca F

    2010-01-01

    Although patient rights is a concept that all nurse managers need to be aware of, this concept often becomes confusing when applied to patients undergoing psychiatric treatment. It is important for the nurse manager to understand the basic rights that psychiatric patients are entitled to, to best be able to help staff nurses under his/her supervision to protect these rights. The nurse manager on a psychiatric unit often serves as a reference for staff nurses, and even for physicians, when questions regarding patient rights present themselves. The nurse manager should be certain to discuss these issues with the facility's legal and risk management team to be aware of particulars of the law of the state in which the facility is located, as state laws may differ somewhat in their treatment of psychiatric patients.

  4. Plasma in dentistry: a review of basic concepts and applications in dentistry.

    PubMed

    Kim, Jae-Hoon; Lee, Mi-Ae; Han, Geum-Jun; Cho, Byeong-Hoon

    2014-01-01

    Plasma-related technologies are essential in modern industries. Recently, plasma has attracted increased attention in the biomedical field. This paper provides a basic knowledge of plasma and a narrative review of plasma applications in dentistry. To review plasma applications in dentistry, an electronic search in PubMed, SCOPUS and Google scholar up to December 2012 was done. This was followed by extensive hand searching using reference lists from relevant articles. There have been attempts to apply plasma technology in various fields of dentistry including surface modifications of dental implants, adhesion, caries treatment, endodontic treatment and tooth bleaching. Although many studies were in early stages, the potential value of plasma for dental applications has been demonstrated. To enlarge the scope of plasma applications and put relevant research to practical use, interdisciplinary research with participation of dental professionals is required.

  5. Optical Nano Antennas: State of the Art, Scope and Challenges as a Biosensor Along with Human Exposure to Nano-Toxicology

    PubMed Central

    Kausar, Abu Sulaiman Mohammad Zahid; Reza, Ahmed Wasif; Latef, Tarik Abdul; Ullah, Mohammad Habib; Karim, Mohammad Ershadul

    2015-01-01

    The concept of optical antennas in physical optics is still evolving. Like the antennas used in the radio frequency (RF) regime, the aspiration of optical antennas is to localize the free propagating radiation energy, and vice versa. For this purpose, optical antennas utilize the distinctive properties of metal nanostructures, which are strong plasmonic coupling elements at the optical regime. The concept of optical antennas is being advanced technologically and they are projected to be substitute devices for detection in the millimeter, infrared, and visible regimes. At present, their potential benefits in light detection, which include polarization dependency, tunability, and quick response times have been successfully demonstrated. Optical antennas also can be seen as directionally responsive elements for point detectors. This review provides an overview of the historical background of the topic, along with the basic concepts and parameters of optical antennas. One of the major parts of this review covers the use of optical antennas in biosensing, presenting biosensing applications with a broad description using different types of data. We have also mentioned the basic challenges in the path of the universal use of optical biosensors, where we have also discussed some legal matters. PMID:25884787

  6. From Syncitium to Regulated Pump: A Cardiac Muscle Cellular Update

    ERIC Educational Resources Information Center

    Korzick, Donna H.

    2011-01-01

    The primary purpose of this article is to present a basic overview of some key teaching concepts that should be considered for inclusion in an six- to eight-lecture introductory block on the regulation of cardiac performance for graduate students. Within the context of cardiac excitation-contraction coupling, this review incorporates information…

  7. Legal Currency in Special Education Law

    ERIC Educational Resources Information Center

    Zirkel, Perry A.

    2011-01-01

    A review of some basic concepts in special education law will help principals better understand the complex laws and regulations implicated in common situations. This article cites a case scenario that illustrates various potential issues under IDEA 2004 and Section 504 of the Rehabilitation Act. Chris is in the 10th grade, and his parents have…

  8. An Introduction to Educational Research: Disciplined Inquiry and Literature Reviews.

    ERIC Educational Resources Information Center

    Evans, Thomas J.

    This paper presents an introduction to basic concepts of educational research for preschool, elementary, and secondary teachers at the Escuela Internacional Sampedrana (EIS) in Honduras who expressed interest in pursuing graduate education in the United States. EIS is a private bilingual (Spanish-English) K-12 school in Honduras. In the first part…

  9. That Figures. A Mathematics Resource Package for Intermediate Grades. Revised.

    ERIC Educational Resources Information Center

    Hintz, Marilyn; Ziegler, Jerry

    This resource package deals with elementary level mathematics in daily living, substituting newspapers as a refreshing change from mathematics texts. A total of 40 exercises are intended to provide review and reinforcement for skills previously taught in formal lessons. Skill or concept areas included are: reading large numbers; basic operations;…

  10. Reinforcing Geometric Properties with Shapedoku Puzzles

    ERIC Educational Resources Information Center

    Wanko, Jeffrey J.; Nickell, Jennifer V.

    2013-01-01

    Shapedoku is a new type of puzzle that combines logic and spatial reasoning with understanding of basic geometric concepts such as slope, parallelism, perpendicularity, and properties of shapes. Shapedoku can be solved by individuals and, as demonstrated here, can form the basis of a review for geometry students as they create their own. In this…

  11. Solar Program Assessment: Environmental Factors - Ocean Thermal Energy Conversion.

    ERIC Educational Resources Information Center

    Energy Research and Development Administration, Washington, DC. Div. of Solar Energy.

    This report presents the environmental problems which may arise with the further development of Ocean Thermal Energy Conversion, one of the eight Federally-funded solar technologies. To provide a background for this environmental analysis, the history and basic concepts of the technology are reviewed, as are its economic and resource requirements.…

  12. BOOK REVIEW: WETLAND DESIGN, PRINCIPLES AND PRACTICES FOR LANDSCAPE ARCHITECTS AND LAND-USE PLANNERS

    EPA Science Inventory

    The book is organized in such a way that it provides a stepwise guide that begins with a basic historical and aesthetic overview of wetland design. The book then summarizes the key concepts involved in cumultive impacts from a landscape ecology persepetive, and then delves furth...

  13. Latest advances in edema

    NASA Technical Reports Server (NTRS)

    Villavicencio, J. L.; Hargens, A. R.; Pikoulicz, E.

    1996-01-01

    Basic concepts in the physiopathology of edema are reviewed. The mechanisms of fluid exchange across the capillary endothelium are explained. Interstitial flow and lymph formation are examined. Clinical disorders of tissue and lymphatic transport, microcirculatory derangements in venous disorders, protein disorders, and lymphatic system disorders are explored. Techniques for investigational imaging of the lymphatic system are explained.

  14. Essential Learnings in Environmental Education--A Database for Building Activities and Programs.

    ERIC Educational Resources Information Center

    Ballard, Melissa, Comp.; Pandya, Mamata, Comp.

    The purpose of this book is to provide building blocks for designing and reviewing environmental education programs and activities. This handbook provides 600 basic concepts needed to attain the environmental education goals outlined at the Tbilisi, USSR, conference and generally agreed to be the fundamental core of quality environmental…

  15. Comorbidity of Anxiety and Conduct Problems in Children: Implications for Clinical Research and Practice

    ERIC Educational Resources Information Center

    Cunningham, Natoshia Raishevich; Ollendick, Thomas H.

    2010-01-01

    Given the relative lack of research on the comorbidity of anxiety disorders (ADs) and conduct problems (oppositional defiant disorder, conduct disorder) in youth, we examine this comorbidity from both basic and applied perspectives. First, we review the concept of comorbidity and provide a framework for understanding issues pertaining to…

  16. Beyond Classroom Borders: Incorporating Collaborative Service Learning for the Adult Student

    ERIC Educational Resources Information Center

    Kelly, Millicent J.

    2013-01-01

    This article provides an overview of collaborative service learning activities as they are incorporated into university curricula designed for the nontraditional student. The basic tenets of the concept of "andragogy" are briefly reviewed to emphasize the special considerations that need to be addressed to ensure the successful inclusion of…

  17. Back to Basics: Unions Reaffirms Their Campus Roles.

    ERIC Educational Resources Information Center

    Blackburn, Richard D.

    1988-01-01

    The role of the college student union is discussed in this review of what makes a union successful. It is suggested that the truly successful one combines the concepts of unifying force, common meeting ground, and community in order to educate as well as generate revenue. Issues considered include: hiring and training employees; competition with…

  18. Science: A Practical View. Volume I. Teacher Edition. Applied Basic Curriculum Series.

    ERIC Educational Resources Information Center

    Evaluation, Dissemination and Assessment Center, Dallas.

    This guide, the first in a series of three, provides the intermediate science student and teacher an opportunity to review selected science concepts and processes through activities which emphasize the applicability of scientific knowledge in the professional world. The three components in this guide deal with (1) ecology (what marine science…

  19. Technical aspects of dental CBCT: state of the art

    PubMed Central

    Araki, K; Siewerdsen, J H; Thongvigitmanee, S S

    2015-01-01

    As CBCT is widely used in dental and maxillofacial imaging, it is important for users as well as referring practitioners to understand the basic concepts of this imaging modality. This review covers the technical aspects of each part of the CBCT imaging chain. First, an overview is given of the hardware of a CBCT device. The principles of cone beam image acquisition and image reconstruction are described. Optimization of imaging protocols in CBCT is briefly discussed. Finally, basic and advanced visualization methods are illustrated. Certain topics in these review are applicable to all types of radiographic imaging (e.g. the principle and properties of an X-ray tube), others are specific for dental CBCT imaging (e.g. advanced visualization techniques). PMID:25263643

  20. Berimbau: A simple instrument for teaching basic concepts in the physics and psychoacoustics of music

    NASA Astrophysics Data System (ADS)

    Vilão, Rui C.; Melo, Santino L. S.

    2014-12-01

    We address the production of musical tones by a simple musical instrument of the Brazilian tradition: the berimbau-de-barriga. The vibration physics of the string and of the air mass inside the gourd are reviewed. Straightforward measurements of an actual berimbau, which illustrate the basic physical phenomena, are performed using a PC-based "soundcard oscilloscope." The inharmonicity of the string and the role of the gourd are discussed in the context of known results in the psychoacoustics of pitch definition.

  1. The availability and accessibility of basic concept vocabulary in AAC software: a preliminary study.

    PubMed

    McCarthy, Jillian H; Schwarz, Ilsa; Ashworth, Morgan

    2017-09-01

    Core vocabulary lists obtained through the analyses of children's utterances include a variety of basic concept words. Supporting young children who use augmentative and alternative communication (AAC) to develop their understanding and use of basic concepts is an area of practice that has important ramifications for successful communication in a classroom environment. This study examined the availability of basic concept words across eight frequently used, commercially available AAC language systems, iPad© applications, and symbol libraries used to create communication boards. The accessibility of basic concept words was subsequently examined using two AAC language page sets and two iPad applications. Results reveal that the availability of basic concept words represented within the different AAC language programs, iPad applications, and symbol libraries varied but was limited across programs. However, there is no significant difference in the accessibility of basic concept words across the language program page sets or iPad applications, generally because all of them require sophisticated motor and cognitive plans for access. These results suggest that educators who teach or program vocabulary in AAC systems need to be mindful of the importance of basic concept words in classroom settings and, when possible, enhance the availability and accessibility of these words to users of AAC.

  2. Time management: a review for physicians.

    PubMed Central

    Brunicardi, F. C.; Hobson, F. L.

    1996-01-01

    This article reviews the basic concepts and techniques of time management as they relate to a medical lifestyle. Essential tools are described to help the physician reassess and sharpen skills for handling intensifying demands and constraints of juggling patient care, research, teaching, and family responsibilities. The historical background and principles of time management for three popular "best selling" techniques are critiqued. In addition, a fourth technique, or model, of time management is introduced for physician use. PMID:8855650

  3. Ultrafast fluorescence spectroscopy via upconversion applications to biophysics.

    PubMed

    Xu, Jianhua; Knutson, Jay R

    2008-01-01

    This chapter reviews basic concepts of nonlinear fluorescence upconversion, a technique whose temporal resolution is essentially limited only by the pulse width of the ultrafast laser. Design aspects for upconversion spectrophotofluorometers are discussed, and a recently developed system is described. We discuss applications in biophysics, particularly the measurement of time-resolved fluorescence spectra of proteins (with subpicosecond time resolution). Application of this technique to biophysical problems such as dynamics of tryptophan, peptides, proteins, and nucleic acids is reviewed.

  4. Topological superconductors: a review.

    PubMed

    Sato, Masatoshi; Ando, Yoichi

    2017-07-01

    This review elaborates pedagogically on the fundamental concept, basic theory, expected properties, and materials realizations of topological superconductors. The relation between topological superconductivity and Majorana fermions are explained, and the difference between dispersive Majorana fermions and a localized Majorana zero mode is emphasized. A variety of routes to topological superconductivity are explained with an emphasis on the roles of spin-orbit coupling. Present experimental situations and possible signatures of topological superconductivity are summarized with an emphasis on intrinsic topological superconductors.

  5. Topological superconductors: a review

    NASA Astrophysics Data System (ADS)

    Sato, Masatoshi; Ando, Yoichi

    2017-07-01

    This review elaborates pedagogically on the fundamental concept, basic theory, expected properties, and materials realizations of topological superconductors. The relation between topological superconductivity and Majorana fermions are explained, and the difference between dispersive Majorana fermions and a localized Majorana zero mode is emphasized. A variety of routes to topological superconductivity are explained with an emphasis on the roles of spin-orbit coupling. Present experimental situations and possible signatures of topological superconductivity are summarized with an emphasis on intrinsic topological superconductors.

  6. Underlying theory of actuarial analyses.

    PubMed

    Benjamin, B

    1985-05-01

    The developments in theory governing the calculation of mortality rates for use in survival measurements working through the initial basic concept of exposure to risk to the later introduction of stochastic elements are reviewed. I have indicated the way in which actuaries and statisticians who work closely with those in the fields of medicine and biology have, by the exchange of methodologic ideas, come to an identity of approach. Recent new actuarial work and likely future developments in actuarial interests are reviewed.

  7. A Look at Handling Qualities of Canard Configurations

    NASA Technical Reports Server (NTRS)

    Anderson, Seth B.

    1986-01-01

    The first human-powered flight was achieved by a canard-configured aircraft (Wright Brothers). Although other canard concepts were flown with varying degrees of success over the years, the tail-aft configuration has dominated the aircraft market for both military and civil use. Reviewed are the development of several canard aircraft with emphasis on stability and control, handling qualities, and operating problems. The results show that early canard concepts suffered adversely in flight behavior because of a lack of understanding of the sensitivities of these concepts to basic stability and control principles. Modern canard designs have been made competitive with tail-aft configurations by using appropriate handling qualities design criteria.

  8. [Systematic reviews of the literature: what should be known about them].

    PubMed

    Manterola, Carlos; Astudillo, Paula; Arias, Esteban; Claros, Nataniel

    2013-03-01

    A systematic review (SR) is an article on the «synthesis of the available evidence», in which a review is performed on the quantitative and qualitative aspects of primary studies, with the aim of summarising the existing information on a particular topic. After collecting the articles of interest the researchers then analyse them and compare the evidence they provide with that from similar ones. The reasons for justifying performing an SR are: when there is uncertainty as regards the effect of an intervention due to there being existing evidence against its real usefulness; when it is desired to know the magnitude of the effect of an intervention; and, when it is desired to analyse the behaviour of an intervention in subject sub-groups. The aim of this article is to perform an update on the basic concepts, indications, strengths and weaknesses of SRs, as well as the development of an SR, the most important potential biases to be taken into account in this type of design, and the basic concepts as regards the meta-analysis. Two examples of SR are also included, of use for surgeons, who often come across this type of design when searching for scientific evidence in biomedical journal bases. Copyright © 2011 AEC. Published by Elsevier Espana. All rights reserved.

  9. The prebiotic concept and human health: a changing landscape with riboflavin as a novel prebiotic candidate?

    PubMed

    Steinert, R E; Sadaghian Sadabad, M; Harmsen, H J M; Weber, P

    2016-12-01

    Emerging evidence suggests that the gut microbiota has a critical role in both the maintenance of human health and the pathogenesis of many diseases. Modifying the colonic microbiota using functional foods has attracted significant research effort and product development. The pioneering concept of prebiotics, as introduced by Gibson and Roberfroid in the 1990s, emphasized the importance of diet in the modulation of the gut microbiota and its relationships to human health. Increasing knowledge of the intestinal microbiota now suggests a more comprehensive definition. This paper briefly reviews the basics of the prebiotic concept with a discussion of recent attempts to refine the concept to open the door for novel prebiotic food ingredients, such as polyphenols, minerals and vitamins.

  10. Basic Science Considerations in Primary Total Hip Replacement Arthroplasty

    PubMed Central

    Mirza, Saqeb B; Dunlop, Douglas G; Panesar, Sukhmeet S; Naqvi, Syed G; Gangoo, Shafat; Salih, Saif

    2010-01-01

    Total Hip Replacement is one of the most common operations performed in the developed world today. An increasingly ageing population means that the numbers of people undergoing this operation is set to rise. There are a numerous number of prosthesis on the market and it is often difficult to choose between them. It is therefore necessary to have a good understanding of the basic scientific principles in Total Hip Replacement and the evidence base underpinning them. This paper reviews the relevant anatomical and biomechanical principles in THA. It goes on to elaborate on the structural properties of materials used in modern implants and looks at the evidence base for different types of fixation including cemented and uncemented components. Modern bearing surfaces are discussed in addition to the scientific basis of various surface engineering modifications in THA prostheses. The basic science considerations in component alignment and abductor tension are also discussed. A brief discussion on modular and custom designs of THR is also included. This article reviews basic science concepts and the rationale underpinning the use of the femoral and acetabular component in total hip replacement. PMID:20582240

  11. Extracting physical chemistry from mechanics: a new approach to investigate DNA interactions with drugs and proteins in single molecule experiments.

    PubMed

    Rocha, M S

    2015-09-01

    In this review we focus on the idea of establishing connections between the mechanical properties of DNA-ligand complexes and the physical chemistry of DNA-ligand interactions. This type of connection is interesting because it opens the possibility of performing a robust characterization of such interactions by using only one experimental technique: single molecule stretching. Furthermore, it also opens new possibilities in comparing results obtained by very different approaches, in particular when comparing single molecule techniques to ensemble-averaging techniques. We start the manuscript reviewing important concepts of DNA mechanics, from the basic mechanical properties to the Worm-Like Chain model. Next we review the basic concepts of the physical chemistry of DNA-ligand interactions, revisiting the most important models used to analyze the binding data and discussing their binding isotherms. Then, we discuss the basic features of the single molecule techniques most used to stretch DNA-ligand complexes and to obtain "force × extension" data, from which the mechanical properties of the complexes can be determined. We also discuss the characteristics of the main types of interactions that can occur between DNA and ligands, from covalent binding to simple electrostatic driven interactions. Finally, we present a historical survey of the attempts to connect mechanics to physical chemistry for DNA-ligand systems, emphasizing a recently developed fitting approach useful to connect the persistence length of DNA-ligand complexes to the physicochemical properties of the interaction. Such an approach in principle can be used for any type of ligand, from drugs to proteins, even if multiple binding modes are present.

  12. Badminton--Teaching Concepts.

    ERIC Educational Resources Information Center

    Gibbs, Marilyn J.

    1988-01-01

    Teaching four basic badminton concepts along with the usual basic skill shots allows players to develop game strategy awareness as well as mechanical skills. These four basic concepts are: (1) ready position, (2) flight trajectory, (3) early shuttle contact, and (4) camouflage. (IAH)

  13. Fundamentals of Acoustics. Psychoacoustics and Hearing. Acoustical Measurements

    NASA Technical Reports Server (NTRS)

    Begault, Durand R.; Ahumada, Al (Technical Monitor)

    1997-01-01

    These are 3 chapters that will appear in a book titled "Building Acoustical Design", edited by Charles Salter. They are designed to introduce the reader to fundamental concepts of acoustics, particularly as they relate to the built environment. "Fundamentals of Acoustics" reviews basic concepts of sound waveform frequency, pressure, and phase. "Psychoacoustics and Hearing" discusses the human interpretation sound pressure as loudness, particularly as a function of frequency. "Acoustic Measurements" gives a simple overview of the time and frequency weightings for sound pressure measurements that are used in acoustical work.

  14. Aerodynamic mathematical modeling - basic concepts

    NASA Technical Reports Server (NTRS)

    Tobak, M.; Schiff, L. B.

    1981-01-01

    The mathematical modeling of the aerodynamic response of an aircraft to arbitrary maneuvers is reviewed. Bryan's original formulation, linear aerodynamic indicial functions, and superposition are considered. These concepts are extended into the nonlinear regime. The nonlinear generalization yields a form for the aerodynamic response that can be built up from the responses to a limited number of well defined characteristic motions, reproducible in principle either in wind tunnel experiments or flow field computations. A further generalization leads to a form accommodating the discontinuous and double valued behavior characteristics of hysteresis in the steady state aerodynamic response.

  15. Global differential geometry: An introduction for control engineers

    NASA Technical Reports Server (NTRS)

    Doolin, B. F.; Martin, C. F.

    1982-01-01

    The basic concepts and terminology of modern global differential geometry are discussed as an introduction to the Lie theory of differential equations and to the role of Grassmannians in control systems analysis. To reach these topics, the fundamental notions of manifolds, tangent spaces, vector fields, and Lie algebras are discussed and exemplified. An appendix reviews such concepts needed for vector calculus as open and closed sets, compactness, continuity, and derivative. Although the content is mathematical, this is not a mathematical treatise but rather a text for engineers to understand geometric and nonlinear control.

  16. A critical narrative review of transfer of basic science knowledge in health professions education.

    PubMed

    Castillo, Jean-Marie; Park, Yoon Soo; Harris, Ilene; Cheung, Jeffrey J H; Sood, Lonika; Clark, Maureen D; Kulasegaram, Kulamakan; Brydges, Ryan; Norman, Geoffrey; Woods, Nicole

    2018-06-01

    'Transfer' is the application of a previously learned concept to solve a new problem in another context. Transfer is essential for basic science education because, to be valuable, basic science knowledge must be transferred to clinical problem solving. Therefore, better understanding of interventions that enhance the transfer of basic science knowledge to clinical reasoning is essential. This review systematically identifies interventions described in the health professions education (HPE) literature that document the transfer of basic science knowledge to clinical reasoning, and considers teaching and assessment strategies. A systematic search of the literature was conducted. Articles related to basic science teaching at the undergraduate level in HPE were analysed using a 'transfer out'/'transfer in' conceptual framework. 'Transfer out' refers to the application of knowledge developed in one learning situation to the solving of a new problem. 'Transfer in' refers to the use of previously acquired knowledge to learn from new problems or learning situations. Of 9803 articles initially identified, 627 studies were retrieved for full text evaluation; 15 were included in the literature review. A total of 93% explored 'transfer out' to clinical reasoning and 7% (one article) explored 'transfer in'. Measures of 'transfer out' fostered by basic science knowledge included diagnostic accuracy over time and in new clinical cases. Basic science knowledge supported learning - 'transfer in' - of new related content and ultimately the 'transfer out' to diagnostic reasoning. Successful teaching strategies included the making of connections between basic and clinical sciences, the use of commonsense analogies, and the study of multiple clinical problems in multiple contexts. Performance on recall tests did not reflect the transfer of basic science knowledge to clinical reasoning. Transfer of basic science knowledge to clinical reasoning is an essential component of HPE that requires further development for implementation and scholarship. © 2018 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

  17. Basic Guidelines for Brain-Compatible Classrooms: Theory to Praxis.

    ERIC Educational Resources Information Center

    Liston, Delores D.

    This paper reviews recent findings in the field of neuroscience that may have a direct impact on specific methodologies and practices in education. It focuses on five concepts from neuroscience: (1) the mind-brain processes symbolic information; (2) neurons are imbued with an epistemic hunger and the mind-brain with a cognitive imperative to learn…

  18. The Basic Tenets of Invitational Theory and Practice: An Invitational Glossary

    ERIC Educational Resources Information Center

    Shaw, Daniel E.; Siegel, Betty L.; Schoenlein, Allyson

    2013-01-01

    A review of the literature which concentrates on Invitational Theory and Practice (ITP) has revealed an inconsistent and oft times confusing or contradictory use of named concepts, labels, phrases, wordings, definitions, and other such titles of major ITP principles (Shaw and Siegel, 2010). Presented in a glossary type format, the purpose of this…

  19. Mapping Latin America for Grades Six to Ten. Third Edition.

    ERIC Educational Resources Information Center

    Stanford Univ., CA. Stanford Program on International and Cross Cultural Education.

    This unit, to be used with students in grades 6-10, has been designed to serve three purposes. First, the unit acts as an introduction to, or review of, fundamental geographic concepts and vocabulary. Second, it teaches students about the basic physical and political geography of Latin America. Third, students learn to examine maps with a critical…

  20. Curriculum Outline for Introduction to Engineering Chemistry. Second Edition. Review Cycle-Annual.

    ERIC Educational Resources Information Center

    Schlenker, Richard M.

    Introduction to Engineering Chemistry is a four-credit hour (one semester) course designed to introduce marine engineering students to the rudiments of basic (introductory) inorganic chemistry. The course consists of 18 units (numbered 1.0 through 18.0) focusing on these subject areas: fundamental concepts; structure of the atom and the periodic…

  1. Applications of statistics to medical science (1) Fundamental concepts.

    PubMed

    Watanabe, Hiroshi

    2011-01-01

    The conceptual framework of statistical tests and statistical inferences are discussed, and the epidemiological background of statistics is briefly reviewed. This study is one of a series in which we survey the basics of statistics and practical methods used in medical statistics. Arguments related to actual statistical analysis procedures will be made in subsequent papers.

  2. Presentation Skills. P.R.I.D.E. People Retraining for Industry Excellence.

    ERIC Educational Resources Information Center

    Burt, Lorna

    This guide, part of a series of workplace-developed materials for retraining factory workers, provides teaching materials for a workplace communication and public speaking course. The course is a review of basic speech concepts focused on helping participants to be comfortable in class discussions and speaking in front of an audience. Topics…

  3. Capabilities of radar as they might relate to entomological studies

    NASA Technical Reports Server (NTRS)

    Skolnik, M. I.

    1979-01-01

    A tutoral background of radar capabilities and its potential for insect research is provided. The basic principles and concepts of radar were reviewed. Information on current radar equipment was examined. Specific issues related to insect research included; target cross-section, radar frequency, tracking target recognition and false alarms, clutter reduction, radar transmitter power, and ascertained atmospheric processes.

  4. Multivariable feedback design - Concepts for a classical/modern synthesis

    NASA Technical Reports Server (NTRS)

    Doyle, J. C.; Stein, G.

    1981-01-01

    This paper presents a practical design perspective on multivariable feedback control problems. It reviews the basic issue - feedback design in the face of uncertainties - and generalizes known single-input, single-output (SISO) statements and constraints of the design problem to multiinput, multioutput (MIMO) cases. Two major MIMO design approaches are then evaluated in the context of these results.

  5. Solar Program Assessment: Environmental Factors - Solar Agricultural and Industrial Process Heat.

    ERIC Educational Resources Information Center

    Energy Research and Development Administration, Washington, DC. Div. of Solar Energy.

    The purpose of this report is to present and prioritize the major environmental issues associated with the further development of solar energy as a source of process heat in the industrial and agricultural sectors. To provide a background for this environmental analysis, the basic concepts and technologies of solar process heating are reviewed.…

  6. The Tradition of Mentoring Part I: Mentoring the Researcher

    ERIC Educational Resources Information Center

    Cheatham, Wayman Wendell

    2010-01-01

    This text is a summary of reflection points and notes from Part I of a two-part lecture on the Tradition of Mentoring. In this lecture, basic historical concepts on the origins of mentoring were reviewed. Of particular importance were several reflections concerning how effective mentoring differs from other forms of leadership and training in the…

  7. Ultrafast Fluorescence Spectroscopy via Upconversion: Applications to Biophysics

    PubMed Central

    Xu, Jianhua; Knutson, Jay R.

    2012-01-01

    This chapter reviews basic concepts of nonlinear fluorescence upconversion, a technique whose temporal resolution is essentially limited only by the pulse width of the ultrafast laser. Design aspects for upconversion spectrophotofluorometers are discussed, and a recently developed system is described. We discuss applications in biophysics, particularly the measurement of time-resolved fluorescence spectra of proteins (with subpicosecond time resolution). Application of this technique to biophysical problems such as dynamics of tryptophan, peptides, proteins, and nucleic acids is reviewed. PMID:19152860

  8. Oscillators and relaxation phenomena in Pleistocene climate theory

    PubMed Central

    Crucifix, Michel

    2012-01-01

    Ice sheets appeared in the northern hemisphere around 3 Ma (million years) ago and glacial–interglacial cycles have paced Earth's climate since then. Superimposed on these long glacial cycles comes an intricate pattern of millennial and sub-millennial variability, including Dansgaard–Oeschger and Heinrich events. There are numerous theories about these oscillations. Here, we review a number of them in order to draw a parallel between climatic concepts and dynamical system concepts, including, in particular, the relaxation oscillator, excitability, slow–fast dynamics and homoclinic orbits. Namely, almost all theories of ice ages reviewed here feature a phenomenon of synchronization between internal climate dynamics and astronomical forcing. However, these theories differ in their bifurcation structure and this has an effect on the way the ice age phenomenon could grow 3 Ma ago. All theories on rapid events reviewed here rely on the concept of a limit cycle excited by changes in the surface freshwater balance of the ocean. The article also reviews basic effects of stochastic fluctuations on these models, including the phenomenon of phase dispersion, shortening of the limit cycle and stochastic resonance. It concludes with a more personal statement about the potential for inference with simple stochastic dynamical systems in palaeoclimate science. PMID:22291227

  9. Approximation concepts for efficient structural synthesis

    NASA Technical Reports Server (NTRS)

    Schmit, L. A., Jr.; Miura, H.

    1976-01-01

    It is shown that efficient structural synthesis capabilities can be created by using approximation concepts to mesh finite element structural analysis methods with nonlinear mathematical programming techniques. The history of the application of mathematical programming techniques to structural design optimization problems is reviewed. Several rather general approximation concepts are described along with the technical foundations of the ACCESS 1 computer program, which implements several approximation concepts. A substantial collection of structural design problems involving truss and idealized wing structures is presented. It is concluded that since the basic ideas employed in creating the ACCESS 1 program are rather general, its successful development supports the contention that the introduction of approximation concepts will lead to the emergence of a new generation of practical and efficient, large scale, structural synthesis capabilities in which finite element analysis methods and mathematical programming algorithms will play a central role.

  10. Applications of nuclear physics

    NASA Astrophysics Data System (ADS)

    Hayes, A. C.

    2017-02-01

    Today the applications of nuclear physics span a very broad range of topics and fields. This review discusses a number of aspects of these applications, including selected topics and concepts in nuclear reactor physics, nuclear fusion, nuclear non-proliferation, nuclear-geophysics, and nuclear medicine. The review begins with a historic summary of the early years in applied nuclear physics, with an emphasis on the huge developments that took place around the time of World War II, and that underlie the physics involved in designs of nuclear explosions, controlled nuclear energy, and nuclear fusion. The review then moves to focus on modern applications of these concepts, including the basic concepts and diagnostics developed for the forensics of nuclear explosions, the nuclear diagnostics at the National Ignition Facility, nuclear reactor safeguards, and the detection of nuclear material production and trafficking. The review also summarizes recent developments in nuclear geophysics and nuclear medicine. The nuclear geophysics areas discussed include geo-chronology, nuclear logging for industry, the Oklo reactor, and geo-neutrinos. The section on nuclear medicine summarizes the critical advances in nuclear imaging, including PET and SPECT imaging, targeted radionuclide therapy, and the nuclear physics of medical isotope production. Each subfield discussed requires a review article unto itself, which is not the intention of the current review; rather, the current review is intended for readers who wish to get a broad understanding of applied nuclear physics.

  11. Applications of nuclear physics

    DOE PAGES

    Hayes-Sterbenz, Anna Catherine

    2017-01-10

    Today the applications of nuclear physics span a very broad range of topics and fields. This review discusses a number of aspects of these applications, including selected topics and concepts in nuclear reactor physics, nuclear fusion, nuclear non-proliferation, nuclear-geophysics, and nuclear medicine. The review begins with a historic summary of the early years in applied nuclear physics, with an emphasis on the huge developments that took place around the time of World War II, and that underlie the physics involved in designs of nuclear explosions, controlled nuclear energy, and nuclear fusion. The review then moves to focus on modern applicationsmore » of these concepts, including the basic concepts and diagnostics developed for the forensics of nuclear explosions, the nuclear diagnostics at the National Ignition Facility, nuclear reactor safeguards, and the detection of nuclear material production and trafficking. The review also summarizes recent developments in nuclear geophysics and nuclear medicine. The nuclear geophysics areas discussed include geo-chronology, nuclear logging for industry, the Oklo reactor, and geo-neutrinos. The section on nuclear medicine summarizes the critical advances in nuclear imaging, including PET and SPECT imaging, targeted radionuclide therapy, and the nuclear physics of medical isotope production. Lastly, each subfield discussed requires a review article unto itself, which is not the intention of the current review; rather, the current review is intended for readers who wish to get a broad understanding of applied nuclear physics.« less

  12. Applications of nuclear physics.

    PubMed

    Hayes, A C

    2017-02-01

    Today the applications of nuclear physics span a very broad range of topics and fields. This review discusses a number of aspects of these applications, including selected topics and concepts in nuclear reactor physics, nuclear fusion, nuclear non-proliferation, nuclear-geophysics, and nuclear medicine. The review begins with a historic summary of the early years in applied nuclear physics, with an emphasis on the huge developments that took place around the time of World War II, and that underlie the physics involved in designs of nuclear explosions, controlled nuclear energy, and nuclear fusion. The review then moves to focus on modern applications of these concepts, including the basic concepts and diagnostics developed for the forensics of nuclear explosions, the nuclear diagnostics at the National Ignition Facility, nuclear reactor safeguards, and the detection of nuclear material production and trafficking. The review also summarizes recent developments in nuclear geophysics and nuclear medicine. The nuclear geophysics areas discussed include geo-chronology, nuclear logging for industry, the Oklo reactor, and geo-neutrinos. The section on nuclear medicine summarizes the critical advances in nuclear imaging, including PET and SPECT imaging, targeted radionuclide therapy, and the nuclear physics of medical isotope production. Each subfield discussed requires a review article unto itself, which is not the intention of the current review; rather, the current review is intended for readers who wish to get a broad understanding of applied nuclear physics.

  13. Applications of nuclear physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hayes-Sterbenz, Anna Catherine

    Today the applications of nuclear physics span a very broad range of topics and fields. This review discusses a number of aspects of these applications, including selected topics and concepts in nuclear reactor physics, nuclear fusion, nuclear non-proliferation, nuclear-geophysics, and nuclear medicine. The review begins with a historic summary of the early years in applied nuclear physics, with an emphasis on the huge developments that took place around the time of World War II, and that underlie the physics involved in designs of nuclear explosions, controlled nuclear energy, and nuclear fusion. The review then moves to focus on modern applicationsmore » of these concepts, including the basic concepts and diagnostics developed for the forensics of nuclear explosions, the nuclear diagnostics at the National Ignition Facility, nuclear reactor safeguards, and the detection of nuclear material production and trafficking. The review also summarizes recent developments in nuclear geophysics and nuclear medicine. The nuclear geophysics areas discussed include geo-chronology, nuclear logging for industry, the Oklo reactor, and geo-neutrinos. The section on nuclear medicine summarizes the critical advances in nuclear imaging, including PET and SPECT imaging, targeted radionuclide therapy, and the nuclear physics of medical isotope production. Lastly, each subfield discussed requires a review article unto itself, which is not the intention of the current review; rather, the current review is intended for readers who wish to get a broad understanding of applied nuclear physics.« less

  14. Examination of the Film "My Father and My Son" According to the Basic Concepts of Multigenerational Family Therapy

    ERIC Educational Resources Information Center

    Acar, Tulin; Voltan-Acar, Nilufer

    2013-01-01

    The aim of this study was to evaluate the basic concepts of multigenerational Family Therapy and to evaluate the scenes of the film ''My Father and My Son'' according to these concepts. For these purposes firstly basic concepts of Multigenerational Family Therapy such as differentiation of self, triangles/triangulation, nuclear family emotional…

  15. nuSTORM and A Path to a Muon Collider

    DOE PAGES

    Adey, David; Bayes, Ryan; Bross, Alan; ...

    2015-05-20

    Our article reviews the current status of the nuSTORM facility and shows how it can be utilized to perform the next step on the path toward the realization of a μ +μ - collider. This review includes the physics motivation behind nuSTORM, a detailed description of the facility and the neutrino beams it can produce, and a summary of the short-baseline neutrino oscillation physics program that can be carried out at the facility. The idea for nuSTORM (the production of neutrino beams from the decay of muons in a racetrack-like decay ring) was discussed in the literature more than 30more » years ago in the context of searching for noninteracting (sterile) neutrinos. However, only in the past 5 years has the concept been fully developed, motivated in large part by the facility's unmatched reach in addressing the evolving data on oscillations involving sterile neutrinos. Finally, this article reviews the basics of the μ +μ -collider concept and describes how nuSTORM provides a platform to test advanced concepts for six-dimensional muon ionization cooling.« less

  16. A fundamental review of the friction and wear behavior of ceramics

    NASA Technical Reports Server (NTRS)

    Buckley, D. H.

    1972-01-01

    The basic concepts associated with the friction and wear of materials are discussed as they relate to ceramics. Properties of ceramics such as crystal structure, crystallographic orientation, mechanical deformation, and surface chemistry are reviewed as they influence friction and wear. Both adhesive and abrasive wear of ceramics are discussed. The friction and wear of ceramics are examined in contact with themselves and when in contact with metals. The influences of environmental constituents such as water and hydrocarbons on friction and wear are reviewed. Materials discussed, by way of example, include aluminum oxide, rutile, calcium fluoride, and lithium fluoride.

  17. Astronomy: A Self-Teaching Guide, 6th Edition

    NASA Astrophysics Data System (ADS)

    Moché, Dinah L.

    2004-02-01

    "A lively, up-to-date account of the basic principles of astronomy and exciting current field of research."-Science Digest For a quarter of a century, Astronomy: A Self-Teaching Guide has been making students and amateur stargazers alike feel at home among the stars. From stars, planets and galaxies, to black holes, the Big Bang and life in space, this title has been making it easy for beginners to quickly grasp the basic concepts of astronomy for over 25 years. Updated with the latest discoveries in astronomy and astrophysics, this newest edition of Dinah Moché's classic guide now includes many Web site addresses for spectacular images and news. And like all previous editions, it is packed with valuable tables, charts, star and moon maps and features simple activities that reinforce readers' grasp of basic concepts at their own pace, as well as objectives, reviews, and self-tests to monitor their progress. Dinah L. Moché, PhD (Rye, NY), is an award-winning author, educator, and lecturer. Her books have sold over nine million copies in seven languages.

  18. Skeletal and dental considerations in orthodontic treatment mechanics: a contemporary view.

    PubMed

    Nanda, Ravindra; Upadhyay, Madhur

    2013-10-01

    Orthodontics has undergone a paradigm shift in the last 40 years. There have been both technical and philosophical changes ushered by the development of new appliances, techniques, and by the explosion in the amount of research being conducted all around the world. However, the application of any new concept requires a firm understanding of the fundamentals of orthodontics. This paper presents a broad review of some fundamental concepts of treatment mechanics that enable us to bring about skeletal and dental correction of the presenting malocclusion. The basic concepts of facemask therapy, mechanics, and biology of tooth movement will be discussed with an insight into the challenges facing us in the future.

  19. Recent advances in approximation concepts for optimum structural design

    NASA Technical Reports Server (NTRS)

    Barthelemy, Jean-Francois M.; Haftka, Raphael T.

    1991-01-01

    The basic approximation concepts used in structural optimization are reviewed. Some of the most recent developments in that area since the introduction of the concept in the mid-seventies are discussed. The paper distinguishes between local, medium-range, and global approximations; it covers functions approximations and problem approximations. It shows that, although the lack of comparative data established on reference test cases prevents an accurate assessment, there have been significant improvements. The largest number of developments have been in the areas of local function approximations and use of intermediate variable and response quantities. It also appears that some new methodologies are emerging which could greatly benefit from the introduction of new computer architecture.

  20. Coherent control of single electrons: a review of current progress

    NASA Astrophysics Data System (ADS)

    Bäuerle, Christopher; Glattli, D. Christian; Meunier, Tristan; Portier, Fabien; Roche, Patrice; Roulleau, Preden; Takada, Shintaro; Waintal, Xavier

    2018-05-01

    In this report we review the present state of the art of the control of propagating quantum states at the single-electron level and its potential application to quantum information processing. We give an overview of the different approaches that have been developed over the last few years in order to gain full control over a propagating single-electron in a solid-state system. After a brief introduction of the basic concepts, we present experiments on flying qubit circuits for ensemble of electrons measured in the low frequency (DC) limit. We then present the basic ingredients necessary to realise such experiments at the single-electron level. This includes a review of the various single-electron sources that have been developed over the last years and which are compatible with integrated single-electron circuits. This is followed by a review of recent key experiments on electron quantum optics with single electrons. Finally we will present recent developments in the new physics that has emerged using ultrashort voltage pulses. We conclude our review with an outlook and future challenges in the field.

  1. Probability, statistics, and computational science.

    PubMed

    Beerenwinkel, Niko; Siebourg, Juliane

    2012-01-01

    In this chapter, we review basic concepts from probability theory and computational statistics that are fundamental to evolutionary genomics. We provide a very basic introduction to statistical modeling and discuss general principles, including maximum likelihood and Bayesian inference. Markov chains, hidden Markov models, and Bayesian network models are introduced in more detail as they occur frequently and in many variations in genomics applications. In particular, we discuss efficient inference algorithms and methods for learning these models from partially observed data. Several simple examples are given throughout the text, some of which point to models that are discussed in more detail in subsequent chapters.

  2. The Internet of Things for basic nursing care-A scoping review.

    PubMed

    Mieronkoski, Riitta; Azimi, Iman; Rahmani, Amir M; Aantaa, Riku; Terävä, Virpi; Liljeberg, Pasi; Salanterä, Sanna

    2017-04-01

    The novel technology of the Internet of Things (IoT) connects objects to the Internet and its most advanced applications refine obtained data for the user. We propose that Internet of Things technology can be used to promote basic nursing care in the hospital environment by improving the quality of care and patient safety. To introduce the concept of Internet of Things to nursing audience by exploring the state of the art of Internet of Things based technology for basic nursing care in the hospital environment. Scoping review methodology following Arksey & O'Malley's stages from one to five were used to explore the extent, range, and nature of current literature. We searched eight databases using predefined search terms. A total of 5030 retrievals were found which were screened for duplications and relevancy to the study topic. 265 papers were chosen for closer screening of the abstracts and 93 for full text evaluation. 62 papers were selected for the review. The constructs of the papers, the Internet of Things based innovations and the themes of basic nursing care in hospital environment were identified. Most of the papers included in the review were peer-reviewed proceedings of technological conferences or articles published in technological journals. The Internet of Things based innovations were presented in methodology papers or tested in case studies and usability assessments. Innovations were identified in several topics in four basic nursing care activities: comprehensive assessment, periodical clinical reassessment, activities of daily living and care management. Internet of Things technology is providing innovations for the use of basic nursing care although the innovations are emerging and still in early stages. Internet of things is yet vaguely adopted in nursing. The possibilities of the Internet of Things are not yet exploited as well as they could. Nursing science might benefit from deeper involvement in engineering research in the area of health. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Cognition before curriculum: rethinking the integration of basic science and clinical learning.

    PubMed

    Kulasegaram, Kulamakan Mahan; Martimianakis, Maria Athina; Mylopoulos, Maria; Whitehead, Cynthia R; Woods, Nicole N

    2013-10-01

    Integrating basic science and clinical concepts in the undergraduate medical curriculum is an important challenge for medical education. The health professions education literature includes a variety of educational strategies for integrating basic science and clinical concepts at multiple levels of the curriculum. To date, assessment of this literature has been limited. In this critical narrative review, the authors analyzed literature published in the last 30 years (1982-2012) using a previously published integration framework. They included studies that documented approaches to integration at the level of programs, courses, or teaching sessions and that aimed to improve learning outcomes. The authors evaluated these studies for evidence of successful integration and to identify factors that contribute to integration. Several strategies at the program and course level are well described but poorly evaluated. Multiple factors contribute to successful learning, so identifying how interventions at these levels result in successful integration is difficult. Evidence from session-level interventions and experimental studies suggests that integration can be achieved if learning interventions attempt to link basic and clinical science in a causal relationship. These interventions attend to how learners connect different domains of knowledge and suggest that successful integration requires learners to build cognitive associations between basic and clinical science. One way of understanding the integration of basic and clinical science is as a cognitive activity occurring within learners. This perspective suggests that learner-centered, content-focused, and session-level-oriented strategies can achieve cognitive integration.

  4. Mines, Quarries and Landscape. Visuality and Transformation

    NASA Astrophysics Data System (ADS)

    Jimeno, Carlos López; Torrijos, Ignacio Díez; González, Carmen Mataix

    2016-06-01

    In this paper a review of two basic concepts is carried out: scenery and landscape integration, proposing a new concept: "visuality", alternative to the classical "visibility" used in landscape studies related to mining activity, which explores the qualitative aspects that define the visual relationships between observer and environment. In relation to landscape integration studies, some reflections on substantive issues are made which induce certain prejudices at the time of addressing the issue of mining operations landscape integration, and some guidance and integration strategies are formulated. In the second part of the text, a new approach to the landscape integration of mines and quarries is raised, closely linked to the concept of visuality which are based on a basic goal: the re-qualification of the place, and give innovative answers to re-qualify the place and show how to catch the opportunity in the deep transformation generated by the development of mining activities. As a conclusion, a case study is presented in the last section, the landscape integration study conducted on marble exploitations Coto Pinos (Alicante, Spain), considered the largest ornamental rock quarry in Europe.

  5. Spectral methods for partial differential equations

    NASA Technical Reports Server (NTRS)

    Hussaini, M. Y.; Streett, C. L.; Zang, T. A.

    1983-01-01

    Origins of spectral methods, especially their relation to the Method of Weighted Residuals, are surveyed. Basic Fourier, Chebyshev, and Legendre spectral concepts are reviewed, and demonstrated through application to simple model problems. Both collocation and tau methods are considered. These techniques are then applied to a number of difficult, nonlinear problems of hyperbolic, parabolic, elliptic, and mixed type. Fluid dynamical applications are emphasized.

  6. Heated Discharge Control and Management Alternatives: Small Water Bodies and Rivers.

    ERIC Educational Resources Information Center

    MacLaren, James F.

    Basic concepts of waste heat management on shallow and deep small water bodies and rivers are reviewed and examples are given. This study defines a small water body as a body in which the far field hydrothermal effects of a heated discharge can be detected in a major portion or practically all of the water body. Environmental effects due to…

  7. Senior Alcohol Services Revisited: Elderly Alcoholism--Current State of the Art.

    ERIC Educational Resources Information Center

    Dunlop, Jean D.

    This report notes the growing awareness of alcohol problems among the elderly during the past 5 to 10 years, and reviews the final conclusions of the federal demonstration project, Senior Alcohol Services. Five basic concepts are included: (1) there are a growing number of elderly persons with alcohol problems (10-15% of all persons over age 60);…

  8. Mathematical modeling of the aerodynamic characteristics in flight dynamics

    NASA Technical Reports Server (NTRS)

    Tobak, M.; Chapman, G. T.; Schiff, L. B.

    1984-01-01

    Basic concepts involved in the mathematical modeling of the aerodynamic response of an aircraft to arbitrary maneuvers are reviewed. The original formulation of an aerodynamic response in terms of nonlinear functionals is shown to be compatible with a derivation based on the use of nonlinear functional expansions. Extensions of the analysis through its natural connection with ideas from bifurcation theory are indicated.

  9. Virtual Reality

    DTIC Science & Technology

    1993-04-01

    until exhausted. SECURITY CLASSIFICATION OF THIS PAGE All other editions are obsolete. UNCLASSIFIED " VIRTUAL REALITY JAMES F. DAILEY, LIEUTENANT COLONEL...US" This paper reviews the exciting field of virtual reality . The author describes the basic concepts of virtual reality and finds that its numerous...potential benefits to society could revolutionize everyday life. The various components that make up a virtual reality system are described in detail

  10. Apollo Onboard Navigation Techniques

    NASA Technical Reports Server (NTRS)

    Interbartolo, Michael

    2009-01-01

    This viewgraph presentation reviews basic navigation concepts, describes coordinate systems and identifies attitude determination techniques including Primary Guidance, Navigation and Control System (PGNCS) IMU management and Command and Service Module Stabilization and Control System/Lunar Module (LM) Abort Guidance System (AGS) attitude management. The presentation also identifies state vector determination techniques, including PGNCS coasting flight navigation, PGNCS powered flight navigation and LM AGS navigation.

  11. Recent applications of spectral methods in fluid dynamics

    NASA Technical Reports Server (NTRS)

    Zang, T. A.; Hussaini, M. Y.

    1985-01-01

    Origins of spectral methods, especially their relation to the method of weighted residuals, are surveyed. Basic Fourier and Chebyshev spectral concepts are reviewed and demonstrated through application to simple model problems. Both collocation and tau methods are considered. These techniques are then applied to a number of difficult, nonlinear problems of hyperbolic, parabolic, elliptic and mixzed type. Fluid dynamical applications are emphasized.

  12. Optical Air Flow Measurements for Flight Tests and Flight Testing Optical Air Flow Meters

    NASA Technical Reports Server (NTRS)

    Jentink, Henk W.; Bogue, Rodney K.

    2005-01-01

    Optical air flow measurements can support the testing of aircraft and can be instrumental to in-flight investigations of the atmosphere or atmospheric phenomena. Furthermore, optical air flow meters potentially contribute as avionics systems to flight safety and as air data systems. The qualification of these instruments for the flight environment is where we encounter the systems in flight testing. An overview is presented of different optical air flow measurement techniques applied in flight and what can be achieved with the techniques for flight test purposes is reviewed. All in-flight optical airflow velocity measurements use light scattering. Light is scattered on both air molecules and aerosols entrained in the air. Basic principles of making optical measurements in flight, some basic optical concepts, electronic concepts, optoelectronic interfaces, and some atmospheric processes associated with natural aerosols are reviewed. Safety aspects in applying the technique are shortly addressed. The different applications of the technique are listed and some typical examples are presented. Recently NASA acquired new data on mountain rotors, mountain induced turbulence, with the ACLAIM system. Rotor position was identified using the lidar system and the potentially hazardous air flow profile was monitored by the ACLAIM system.

  13. Introduction to polymer-based solid-contact ion-selective electrodes-basic concepts, practical considerations, and current research topics.

    PubMed

    Bieg, Christoph; Fuchsberger, Kai; Stelzle, Martin

    2017-01-01

    This review aims at providing an introductory overview for researchers new to the field of ion-selective electrodes. Both state of the art technology and novel developments towards solid-contact reference (sc-RE) and solid-contact ion selective electrodes (sc-ISE) are discussed. This technology has potentially widespread and important applications provided certain performance criteria can be met. We present basic concepts, operation principles, and theoretical considerations with regard to their function. Analytical performance and suitability of sc-RE and sc-ISE for a given application depend on critical parameters, which are discussed in this review. Comprehensive evaluation of sensor performance along this set of parameters is considered indispensable to allow for a well-founded comparison of different technologies. Methods and materials employed in the construction of sc-RE and sc-ISE, in particular the solid contact and the polymer membrane composite, are presented and discussed in detail. Operation principles beyond potentiometry are mentioned, which would further extend the field of ISE application. Finally, we conclude by directing the reader to important areas for further scientific research and development work considered particularly critical and promising for advancing this field in sensor R&D. Graphical Abstract ᅟ.

  14. De-implementation: A concept analysis.

    PubMed

    Upvall, Michele J; Bourgault, Annette M

    2018-04-25

    The purpose of this concept analysis is to explore the meaning of de-implementation and provide a definition that can be used by researchers and clinicians to facilitate evidence-based practice. De-implementation is a relatively unknown process overshadowed by the novelty of introducing new ideas and techniques into practice. Few studies have addressed the challenge of de-implementation and the cognitive processes involved when terminating harmful or unnecessary practices. Also, confusion exists regarding the myriad of terms used to describe de-implementation processes. Walker and Avant's method (2011) for describing concepts was used to clarify de-implementation. A database search limited to academic journals yielded 281 publications representing basic research, study protocols, and editorials/commentaries from implementation science experts. After applying exclusion criterion of English language only and eliminating overlap between databases, 41 articles were selected for review. Literature review and synthesis provided a concept analysis and a distinct definition of de-implementation. De-implementation was defined as the process of identifying and removing harmful, non-cost-effective, or ineffective practices based on tradition and without adequate scientific support. The analysis provided further refinement of de-implementation as a significant concept for ongoing theory development in implementation science and clinical practice. © 2018 Wiley Periodicals, Inc.

  15. Analyzing the Relationship between Learning Styles and Basic Concept Knowledge Level of Kindergarten Children

    ERIC Educational Resources Information Center

    Balat, Gülden Uyanik

    2014-01-01

    Most basic concepts are acquired during preschool period. There are studies indicating that the basic concept knowledge of children is related to language development, cognitive development, academic achievement and intelligence. The relationship between learning behaviors (sometime called learning or cognitive styles) and a child academic success…

  16. Piloted aircraft simulation concepts and overview

    NASA Technical Reports Server (NTRS)

    Sinacori, J. B.

    1978-01-01

    An overview of piloted aircraft simulation is presented that reflects the viewpoint of an aeronautical technologist. The intent is to acquaint potential users with some of the basic concepts and issues that characterize piloted simulation. Application to the development of aircraft are highlighted, but some aspects of training simulators are covered. A historical review is given together with a description of some current simulators. Simulator usages, advantages, and limitations are discussed and human perception qualities important to simulation are related. An assessment of current simulation is presented that addresses validity, fidelity, and deficiencies. Future prospects are discussed and technology projections are made.

  17. Recent developments in learning control and system identification for robots and structures

    NASA Technical Reports Server (NTRS)

    Phan, M.; Juang, J.-N.; Longman, R. W.

    1990-01-01

    This paper reviews recent results in learning control and learning system identification, with particular emphasis on discrete-time formulation, and their relation to adaptive theory. Related continuous-time results are also discussed. Among the topics presented are proportional, derivative, and integral learning controllers, time-domain formulation of discrete learning algorithms. Newly developed techniques are described including the concept of the repetition domain, and the repetition domain formulation of learning control by linear feedback, model reference learning control, indirect learning control with parameter estimation, as well as related basic concepts, recursive and non-recursive methods for learning identification.

  18. The BCS-BEC Crossover

    NASA Astrophysics Data System (ADS)

    Parish, Meera M.

    2015-09-01

    This chapter presents the crossover from the Bardeen-Cooper-Schrieffer (BCS) state of weakly correlated pairs of fermions to the Bose-Einstein condensation (BEC) of diatomic molecules in the atomic Fermi gas. Our aim is to provide a pedagogical review of the BCS-BEC crossover, with an emphasis on the basic concepts, particularly those that are not generally known or are difficult to find in the literature. We shall not attempt to give an exhaustive survey of current research in the limited space here; where possible, we will direct the reader to more extensive reviews.

  19. High temperature NASP engine seals: A technology review

    NASA Technical Reports Server (NTRS)

    Steinetz, Bruce M.; Dellacorte, Christopher; Tong, Mike

    1991-01-01

    Progress in developing advanced high temperature engine seal concepts and related sealing technologies for advanced hypersonic engines are reviewed. Design attributes and issues requiring further development for both the ceramic wafer seal and the braided ceramic rope seal are examined. Leakage data are presented for these seals for engine simulated pressure and temperature conditions and compared to a target leakage limit. Basic elements of leakage flow models to predict leakage rates for each of these seals over the wide range of pressure and temperature conditions anticipated in the engine are also presented.

  20. [Basic symptoms in schizophrenia, their clinical study and relevance in research].

    PubMed

    Miret, Salvador; Fatjó-Vilas, Mar; Peralta, Víctor; Fañanás, Lourdes

    2016-01-01

    Basic symptoms consist of subtle sub-clinical disturbances subjectively experienced by schizophrenia patients. These are mainly related to drive, affect, thinking and language, perception, memory, motor action, central vegetative functions, control of cognitive processes, and stress tolerance. Initially described by Huber, from a phenomenological approach, basic symptoms are part of the earliest features of schizophrenia, and they can evolve along the course of the disorder. Their assessment during the prodromal phase of the disease (together with ultra-high risk criteria) is one of the 2 main approaches that allow the definition of states of clinical risk for the development of psychosis. The present review provides an updated view of the concept of basic symptoms, highlighting its potential value in establishing neurobiological correlates of interest in aetiopathogenic research. Copyright © 2015 SEP y SEPB. Published by Elsevier España. All rights reserved.

  1. What is Basic Research? Insights from Historical Semantics.

    PubMed

    Schauz, Désirée

    2014-01-01

    For some years now, the concept of basic research has been under attack. Yet although the significance of the concept is in doubt, basic research continues to be used as an analytical category in science studies. But what exactly is basic research? What is the difference between basic and applied research? This article seeks to answer these questions by applying historical semantics. I argue that the concept of basic research did not arise out of the tradition of pure science. On the contrary, this new concept emerged in the late 19th and early 20th centuries, a time when scientists were being confronted with rising expectations regarding the societal utility of science. Scientists used the concept in order to try to bridge the gap between the promise of utility and the uncertainty of scientific endeavour. Only after 1945, when United States science policy shaped the notion of basic research, did the concept revert to the older ideals of pure science. This revival of the purity discourse was caused by the specific historical situation in the US at that time: the need to reform federal research policy after the Second World War, the new dimension of ethical dilemmas in science and technology during the atomic era, and the tense political climate during the Cold War.

  2. The Absolutely Basic Concepts of being a nurse entrepreneur.

    PubMed

    Kaplan, S M

    1991-01-01

    As nurses become more comfortable with the notion of entrepreneurial practice in a setting that may take them outside of the traditional hospital or outpatient milieu, there are a number of considerations that need to be addressed. The purpose of this article is to review many of these points in a succinct and practical fashion for the nurse who may be considering such a move.

  3. La ciencia en la vida actual. Volumen I. Edicion para el maestro (Science in Everyday Life. Volume I. Teacher Edition). Applied Basic Curriculum Series.

    ERIC Educational Resources Information Center

    Evaluation, Dissemination and Assessment Center, Dallas.

    This guide, the first in a series of three, provides the Spanish-speaking intermediate science student and teacher an opportunity to review selected science concepts and processes through activities which emphasize the applicability of scientific knowledge in the professional world. The three components in this guide deal with (1) ecology (what…

  4. La ciencia en la vida actual. Volumen II. Edicion para el maestro (Science in Everyday Life. Volume II. Teacher Edition). Applied Basic Curriculum Series.

    ERIC Educational Resources Information Center

    Evaluation, Dissemination and Assessment Center, Dallas.

    This guide, the second in a series of three, provides the Spanish-speaking intermediate science student and teacher an opportunity to review selected science concepts and processes through activities which emphasize the applicability of scientific knowledge in the professional world. This guide is divided into three components. The first component…

  5. La ciencia en la vida actual. Volumen III. Edicion para el maestro (Science in Everyday Life. Volume III. Teacher Edition). Applied Basic Curriculum Series.

    ERIC Educational Resources Information Center

    Evaluation, Dissemination and Assessment Center, Dallas.

    This guide, the third in a series of three, provides the Spanish-speaking intermediate science student and teacher an opportunity to review selected science concepts and processes through activities which emphasize the applicability of scientific knowledge in the professional world. The three components in this guide deal with (1) the scientific…

  6. Illuminating Engineering Research Institute Annual Report 1967. A Review of Project Activities and a Roundup of IERI Research Interests.

    ERIC Educational Resources Information Center

    Illuminating Engineering Research Inst., New York, NY.

    Presented in this report are the Illuminating Engineering Research Institute's fundamental scientific concepts in a new frame of realism while relating them to an up-to-date accounting of the search for new basic knowledge. In addition to being an annual accounting, it is also intended to provide orientation. Its presented in dramatic and…

  7. Approaches to Machine Learning.

    DTIC Science & Technology

    1984-02-16

    The field of machine learning strives to develop methods and techniques to automatic the acquisition of new information, new skills, and new ways of organizing existing information. In this article, we review the major approaches to machine learning in symbolic domains, covering the tasks of learning concepts from examples, learning search methods, conceptual clustering, and language acquisition. We illustrate each of the basic approaches with paradigmatic examples. (Author)

  8. Metrication of clinical laboratory data in SI units.

    PubMed

    Lehmann, H P

    1976-01-01

    The development and general concepts of the Système International d'Unités (SI units) are discussed. The basic and derived quantities and units of the SI used for clinical laboratory data are reviewed. Ranges of normal values for a number of body fluid constituents are given in the units in current general use and in SI units, with corresponding conversion factors.

  9. Equal Educational Opportunity. The Status of Black Americans in Higher Education, 1975-1977. ISEP Third Status Report.

    ERIC Educational Resources Information Center

    Howard Univ., Washington, DC. Inst. for the Study of Educational Policy.

    This report analyzes the status of black Americans in higher education from 1975-1977. The book opens with a review of basic concepts of equal educational opportunity and the Federal role in guaranteeing equal opportunity. The social and economic context for higher education is then examined with a focus on the national commitment to higher…

  10. Positioning hospitals: a model for regional hospitals.

    PubMed

    Reddy, A C; Campbell, D P

    1993-01-01

    In an age of marketing warfare in the health care industry, hospitals need creative strategies to compete successfully. Lately, positioning concepts have been added to the health care marketer's arsenal of strategies. To blend theory with practice, the authors review basic positioning theory and present a framework for developing positioning strategies. They also evaluate the marketing strategies of a regional hospital to provide a case example.

  11. An overview of general aviation propulsion research programs at NASA Lewis Research Center

    NASA Technical Reports Server (NTRS)

    Willis, E. A.; Strack, W. C.

    1981-01-01

    The review covers near-term improvements for current-type piston engines, as well as studies and limited corroborative research on several advanced g/a engine concepts, including diesels, small turboprops and both piston and rotary stratified-charge engines. Also described is basic combustion research, cycle modeling and diagnostic instrumentation work that is required to make new engines a reality.

  12. Solar electric propulsion system technology

    NASA Technical Reports Server (NTRS)

    Masek, T. D.; Macie, T. W.

    1971-01-01

    Achievements in the solar electric propulsion system technology program (SEPST 3) are reported and certain propulsion system-spacecraft interaction problems are discussed. The basic solar electric propulsion system concept and elements are reviewed. Hardware is discussed only briefly, relying on detailed fabrication or assembly descriptions reported elsewhere. Emphasis is placed on recent performance data, which are presented to show the relationship between spacecraft requirements and present technology.

  13. High frequency x-ray generator basics.

    PubMed

    Sobol, Wlad T

    2002-02-01

    The purpose of this paper is to present basic functional principles of high frequency x-ray generators. The emphasis is put on physical concepts that determine the engineering solutions to the problem of efficient generation and control of high voltage power required to drive the x-ray tube. The physics of magnetically coupled circuits is discussed first, as a background for the discussion of engineering issues related to high-frequency power transformer design. Attention is paid to physical processes that influence such factors as size, efficiency, and reliability of a high voltage power transformer. The basic electrical circuit of a high frequency generator is analyzed next, with focus on functional principles. This section investigates the role and function of basic components, such as power supply, inverter, and voltage doubler. Essential electronic circuits of generator control are then examined, including regulation of voltage, current and timing of electrical power delivery to the x-ray tube. Finally, issues related to efficient feedback control, including basic design of the AEC circuitry are reviewed.

  14. Basic science curriculums in nuclear cardiology and cardiovascular imaging: evolving and emerging concepts.

    PubMed

    Van Decker, William A; Villafana, Theodore

    2008-01-01

    The teaching of basic science with regard to physics, instrumentation, and radiation safety has been part of nuclear cardiology training since its inception. Although there are clear educational and quality rationale for such, regulations associated with the Nuclear Regulatory Commission Subpart J of old 10 CFR section 35 (Title 10, Code of Federal Regulations, Part 35) from the 1960s mandated such prescriptive instruction. Cardiovascular fellowship training programs now have a new opportunity to rethink their basic science imaging curriculums with the era of "revised 10 CFR section 35" and the growing implementation of multimodality imaging training and expertise. This review focuses on the history and the why, what, and how of such a curriculum arising in one city and suggests examples of future implementation in other locations.

  15. Advanced Taste Sensors Based on Artificial Lipids with Global Selectivity to Basic Taste Qualities and High Correlation to Sensory Scores

    PubMed Central

    Kobayashi, Yoshikazu; Habara, Masaaki; Ikezazki, Hidekazu; Chen, Ronggang; Naito, Yoshinobu; Toko, Kiyoshi

    2010-01-01

    Effective R&D and strict quality control of a broad range of foods, beverages, and pharmaceutical products require objective taste evaluation. Advanced taste sensors using artificial-lipid membranes have been developed based on concepts of global selectivity and high correlation with human sensory score. These sensors respond similarly to similar basic tastes, which they quantify with high correlations to sensory score. Using these unique properties, these sensors can quantify the basic tastes of saltiness, sourness, bitterness, umami, astringency and richness without multivariate analysis or artificial neural networks. This review describes all aspects of these taste sensors based on artificial lipid, ranging from the response principle and optimal design methods to applications in the food, beverage, and pharmaceutical markets. PMID:22319306

  16. Basic Microbiologic and Infection Control Information to Reduce the Potential Transmission of Pathogens to Patients via Computer Hardware

    PubMed Central

    Neely, Alice N.; Sittig, Dean F.

    2002-01-01

    Computer technology from the management of individual patient medical records to the tracking of epidemiologic trends has become an essential part of all aspects of modern medicine. Consequently, computers, including bedside components, point-of-care testing equipment, and handheld computer devices, are increasingly present in patients’ rooms. Recent articles have indicated that computer hardware, just as other medical equipment, may act as a reservoir for microorganisms and contribute to the transfer of pathogens to patients. This article presents basic microbiological concepts relative to infection, reviews the present literature concerning possible links between computer contamination and nosocomial colonizations and infections, discusses basic principles for the control of contamination, and provides guidelines for reducing the risk of transfer of microorganisms to susceptible patient populations. PMID:12223502

  17. Emergence and Phase Transitions

    NASA Astrophysics Data System (ADS)

    Sikkema, Arnold

    2006-05-01

    Phase transitions are well defined in physics through concepts such as spontaneous symmetry breaking, order parameter, entropy, and critical exponents. But emergence --- also exhibiting whole-part relations (such as top-down influence), unpredictability, and insensitivity to microscopic detail --- is a loosely-defined concept being used in many disciplines, particularly in psychology, biology, philosophy, as well as in physics[1,2]. I will review the concepts of emergence as used in the various fields and consider the extent to which the methods of phase transitions can clarify the usefulness of the concept of emergence both within the discipline of physics and beyond.1. Robert B. Laughlin, A Different Universe: Reinventing Physics from the Bottom Down (New York: Basic Books, 2005). 2. George F.R. Ellis, ``Physics and the Real World'', Physics Today, vol. 58, no. 7 (July 2005) pp. 49-54.

  18. A review of the basic concepts of dense gas dispersion with special regard to modelling of heat transfer

    NASA Astrophysics Data System (ADS)

    Tasker, M. N.

    1984-01-01

    Dense gas dispersion is the study of the spreading and dilution of a gas that has a density greater than that of ambient air. Models to predict the dispersion of such dense gases as chlorine, sulfur dioxide, liquefied natural gas, and liquid propane are necessary to prevent a catastrophe in environmental and/or human terms. A basic physical picture of dense gas dispersion is provided. Mathematical and wind tunnel models of dense gas flow are presented and discussed, including the constraints and disadvantages of modelling techniques. Special emphasis is given to heat transfer during dense gas dispersion.

  19. Behavioral Economic Factors Related to Pediatric Obesity

    PubMed Central

    Greenwald, Mark K.

    2016-01-01

    Summary The field of behavioral economics suggests that food and activity choices are governed by costs, available alternatives, and reinforcement. Here, we review basic and translational research using a behavioral economic (BE) framework with overweight or obese children up to age 18. We address BE concepts and methods, discuss developmental issues, the continuum of BE intervention approaches, findings of studies focused on increasing the cost of unwanted behaviors (i.e., energy-dense food intake and sedentary behavior) and decreasing the cost of desired behaviors (i.e., healthy food intake and PA), and our team's recent basic behavioral studies using BE approaches with minority adolescents. PMID:27261543

  20. Microscopy basics and the study of actin-actin-binding protein interactions.

    PubMed

    Thomasson, Maggie S; Macnaughtan, Megan A

    2013-12-15

    Actin is a multifunctional eukaryotic protein with a globular monomer form that polymerizes into a thin, linear microfilament in cells. Through interactions with various actin-binding proteins (ABPs), actin plays an active role in many cellular processes, such as cell motility and structure. Microscopy techniques are powerful tools for determining the role and mechanism of actin-ABP interactions in these processes. In this article, we describe the basic concepts of fluorescent speckle microscopy, total internal reflection fluorescence microscopy, atomic force microscopy, and cryoelectron microscopy and review recent studies that utilize these techniques to visualize the binding of actin with ABPs. Copyright © 2013 Elsevier Inc. All rights reserved.

  1. Craft-Art as a Basis for Human Activity

    ERIC Educational Resources Information Center

    Karppinen, Seija

    2008-01-01

    This article based on my doctoral thesis examines the Basic Arts Education system in Finland, focusing on Basic Crafts Education and its description through action concepts. The main task of the study was to create a concept model. In the first part of the study a concept map was created from the practice of Basic Crafts Education. The aim of the…

  2. Master Curriculum Guide in Economics for the Nation's Schools. Part I, A Framework for Teaching Economics: Basic Concepts.

    ERIC Educational Resources Information Center

    Hansen, W. Lee; And Others

    A concise framework of basic concepts and generalizations for teaching economics for K-12 students is presented. The guide summarizes the basic structure and substance of economics and lists and describes economic concepts. Standard guidelines are provided to help school systems integrate economics into their on-going courses of study. Designed to…

  3. Creation and implementation of a flipped jigsaw activity to stimulate interest in biochemistry among medical students.

    PubMed

    Williams, Charlene; Perlis, Susan; Gaughan, John; Phadtare, Sangita

    2018-05-06

    Learner-centered pedagogical methods that are based on clinical application of basic science concepts through active learning and problem solving are shown to be effective for improving knowledge retention. As the clinical relevance of biochemistry is not always apparent to health-profession students, effective teaching of medical biochemistry should highlight the implications of biochemical concepts in pathology, minimize memorization, and make the concepts memorable for long-term retention. Here, we report the creation and successful implementation of a flipped jigsaw activity that was developed to stimulate interest in learning biochemistry among medical students. The activity combined the elements of a flipped classroom for learning concepts followed by a jigsaw activity to retrieve these concepts by solving clinical cases, answering case-based questions, and creating concept maps. The students' reception of the activity was very positive. They commented that the activity provided them an opportunity to review and synthesize information, helped to gage their learning by applying this information and work with peers. Students' improved performance especially for answering the comprehension-based questions correctly in the postquiz as well as the depth of information included in the postquiz concept maps suggested that the activity helped them to understand how different clinical scenarios develop owing to deviations in basic biochemical pathways. Although this activity was created for medical students, the format of this activity can also be useful for other health-professional students as well as undergraduate and graduate students. © 2018 by The International Union of Biochemistry and Molecular Biology, 2018. © 2018 The International Union of Biochemistry and Molecular Biology.

  4. The Articulation of Integration of Clinical and Basic Sciences in Concept Maps: Differences between Experienced and Resident Groups

    ERIC Educational Resources Information Center

    Vink, Sylvia; van Tartwijk, Jan; Verloop, Nico; Gosselink, Manon; Driessen, Erik; Bolk, Jan

    2016-01-01

    To determine the content of integrated curricula, clinical concepts and the underlying basic science concepts need to be made explicit. Preconstructed concept maps are recommended for this purpose. They are mainly constructed by experts. However, concept maps constructed by residents are hypothesized to be less complex, to reveal more tacit basic…

  5. The Analysis of the Understanding Levels of Teacher Candidates in Different Departments about Basic Astronomy Concepts

    ERIC Educational Resources Information Center

    Durukan, Ümmü Gülsüm; Saglam-Arslan, Aysegül

    2015-01-01

    Learners face a variety of concepts during the instructional process they experience. These concepts are mostly introduced by teachers; thus, the competences of teachers in terms of teaching concepts are vitally important. The aim of this study is to detect the understanding levels of teacher candidates about basic astronomy concepts. The method…

  6. Proven and novel strategies for efficient editing of the human genome.

    PubMed

    Mussolino, Claudio; Mlambo, Tafadzwa; Cathomen, Toni

    2015-10-01

    Targeted gene editing with designer nucleases has become increasingly popular. The most commonly used designer nuclease platforms are engineered meganucleases, zinc-finger nucleases, transcription activator-like effector nucleases and the clustered regularly interspaced short palindromic repeat/Cas9 system. These powerful tools have greatly facilitated the generation of plant and animal models for basic research, and harbor an enormous potential for applications in biotechnology and gene therapy. This review recapitulates proven concepts of targeted genome engineering in primary human cells and elaborates on novel concepts that became possible with the dawn of RNA-guided nucleases and RNA-guided transcription factors. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Self-awareness: a review and analysis of a basic nursing concept.

    PubMed

    Eckroth-Bucher, Margie

    2010-01-01

    Self-awareness has long been addressed as fundamental for the professional nurse with the accepted view that self-awareness will lead to greater competence. Therefore, it is important to understand the historical evolution of the concept, attributes, antecedents, and consequences. Rodgers' evolutionary method was used for critical analysis of nursing, social sciences, and education literature. Analysis indicates that self-awareness is a dynamic, transformative process of self. Ultimately, self-awareness is the use of self-insights and presence knowingly to guide behavior that is genuine and authentic to create a healing interpersonal environment. Future research areas within practice and education are identified.

  8. Book Review: Dolores Knipp’s Understanding Space Weather and the Physics Behind It

    NASA Astrophysics Data System (ADS)

    Moldwin, Mark

    2012-08-01

    Delores Knipp's textbook Understanding Space Weather and the Physics Behind It provides a comprehensive resource for space physicists teaching in a variety of academic departments to introduce space weather to advanced undergraduates. The book benefits from Knipp's extensive experience teaching introductory and advanced undergraduate physics courses at the U.S. Air Force Academy. The fundamental physics concepts are clearly explained and are connected directly to the space physics concepts being discussed. To expand upon the relevant basic physics, current research areas and new observations are highlighted, with many of the chapters including contributions from a number of leading space physicists.

  9. Cross-cultural perspectives on the concept of retirement: An analytic redefinition

    PubMed Central

    LUBORSKY, MARK R.; LEBLANC, IAN M.

    2014-01-01

    A cross-cultural valid analytic definition of retirement remains elusive in gerontology despite a long tradition of research on the topic. Inadequate attention has been paid to consistently defining the key concepts used to examine retirement and to specifying its occurrence in non-Western, non-industrial societies. This paper critically reviews basic cultural tenets in the notion of retirement, and proposes a more comparatively valid definition. It then proposes a three part comparative categorization by exploring retirement in contemporary Western nations and comparing it with retirement-like practices from a range of non-Western cultures including Thai, Chinese, Ladak, Fulani, Lusi and Aymara. PMID:14654730

  10. Conceptual Foundations of Systems Biology Explaining Complex Cardiac Diseases.

    PubMed

    Louridas, George E; Lourida, Katerina G

    2017-02-21

    Systems biology is an important concept that connects molecular biology and genomics with computing science, mathematics and engineering. An endeavor is made in this paper to associate basic conceptual ideas of systems biology with clinical medicine. Complex cardiac diseases are clinical phenotypes generated by integration of genetic, molecular and environmental factors. Basic concepts of systems biology like network construction, modular thinking, biological constraints (downward biological direction) and emergence (upward biological direction) could be applied to clinical medicine. Especially, in the field of cardiology, these concepts can be used to explain complex clinical cardiac phenotypes like chronic heart failure and coronary artery disease. Cardiac diseases are biological complex entities which like other biological phenomena can be explained by a systems biology approach. The above powerful biological tools of systems biology can explain robustness growth and stability during disease process from modulation to phenotype. The purpose of the present review paper is to implement systems biology strategy and incorporate some conceptual issues raised by this approach into the clinical field of complex cardiac diseases. Cardiac disease process and progression can be addressed by the holistic realistic approach of systems biology in order to define in better terms earlier diagnosis and more effective therapy.

  11. [Longevity control in fungi and other organisms. The conception of scales].

    PubMed

    Mazheĭka, I S; Kudriavtseva, O A; Kamzolkina, O V

    2011-01-01

    The review deals mainly with gerontological processes that occur on the cellular-colonial level of organization in fungi and cellular-tissular level in other organisms. Aging and anti-aging mechanisms operating on these levels of organization can be considered as common ones for all living things. Fungi, as an object with tissular-like organization of thallus, afford a broad spectrum of possibilities as to solving the tasks of general gerontological import. Three basic (chronological, replicative, and cell-suicidal) and several auxiliary mechanisms of aging are singled out, the classification is given of stochastic aging factors accumulating in cells. It is shown that in complex multi-cellular organisms, aging and anti-aging mechanisms operate on the level of interactions between tissues, though in the base of their actions lie the aforesaid conservative basic mechanisms. Preliminary generalized conception of aging--the conception of scales--is put forward that is founded on the model of balanced and non-balanced counteractions between stressful impacts and various mechanisms of aging and anti-aging with different extent of genetic preprogramming. The importance is reaffirmed of mycological gerontology contribution to broadening of inferences on aging nature.

  12. Addressing Point of Need in Interactive Multimedia Instruction: A Conceptual Review and Evaluation

    DTIC Science & Technology

    2013-11-01

    classroom setting, ability grouping refers to the practice of putting students into groups on the basis of individual group members’ ability levels...presentation of elaborated/basic vs. advanced material, color cuing, pretesting and modifying learning presentation based on performance) ...learners’ points of need. The point of need concept is focused both on the accessibility of information to support the learning process as well as

  13. [Cluster analysis in biomedical researches].

    PubMed

    Akopov, A S; Moskovtsev, A A; Dolenko, S A; Savina, G D

    2013-01-01

    Cluster analysis is one of the most popular methods for the analysis of multi-parameter data. The cluster analysis reveals the internal structure of the data, group the separate observations on the degree of their similarity. The review provides a definition of the basic concepts of cluster analysis, and discusses the most popular clustering algorithms: k-means, hierarchical algorithms, Kohonen networks algorithms. Examples are the use of these algorithms in biomedical research.

  14. Superconducting applications in propulsion systems. Magnetic insulation for plasma propulsion devices

    NASA Technical Reports Server (NTRS)

    Gonzalez, Dora E.; Karr, Gerald R.

    1990-01-01

    The purpose of this paper is to review the status of knowledge of the basic concepts needed to establish design parameters for effective magnetic insulation. The objective is to estimate the effectiveness of the magnetic field in insulating the plasma, to calculate the magnitude of the magnetic field necessary to reduce the heat transfer to the walls sufficiently enough to demonstrate the potential of magnetically driven plasma rockets.

  15. An overview of artificial intelligence and robotics. Volume 2: Robotics

    NASA Technical Reports Server (NTRS)

    Gevarter, W. B.

    1982-01-01

    This report provides an overview of the rapidly changing field of robotics. The report incorporates definitions of the various types of robots, a summary of the basic concepts, utilized in each of the many technical areas, review of the state of the art and statistics of robot manufacture and usage. Particular attention is paid to the status of robot development, the organizations involved, their activities, and their funding.

  16. Fusion Studies in Japan

    NASA Astrophysics Data System (ADS)

    Ogawa, Yuichi

    2016-05-01

    A new strategic energy plan decided by the Japanese Cabinet in 2014 strongly supports the steady promotion of nuclear fusion development activities, including the ITER project and the Broader Approach activities from the long-term viewpoint. Atomic Energy Commission (AEC) in Japan formulated the Third Phase Basic Program so as to promote an experimental fusion reactor project. In 2005 AEC has reviewed this Program, and discussed on selection and concentration among many projects of fusion reactor development. In addition to the promotion of ITER project, advanced tokamak research by JT-60SA, helical plasma experiment by LHD, FIREX project in laser fusion research and fusion engineering by IFMIF were highly prioritized. Although the basic concept is quite different between tokamak, helical and laser fusion researches, there exist a lot of common features such as plasma physics on 3-D magnetic geometry, high power heat load on plasma facing component and so on. Therefore, a synergetic scenario on fusion reactor development among various plasma confinement concepts would be important.

  17. Basic concepts of depression

    PubMed Central

    Paykel, Eugene S.

    2008-01-01

    This paper reviews concepts of depression, including history and classification. The original broad concept of melancholia included all forms of quiet insanity. The term depression began to appear in the nineteenth century as did the modern concept of affective disorders, with the core disturbance now viewed as one of mood. The 1930s saw the introduction of defined criteria into official diagnostic schemes. The modern separation into unipolar and bipolar disorder was introduced following empirical research by Angst and Perris in the 1960s. The partially overlapping distinctions between psychotic and neurotic depression, and between endogenous and reactive depression, started to generate debate in the 1920s, with considerable multivariate research in the 1960s. The symptom element in endogenous depression currently survives in melancholia or somatic syndrome. Life stress is common in various depressive pictures. Dysthymia, a valuable diagnosis, represents a form of what was regarded earlier as neurotic depression. Other subtypes are also discussed. PMID:18979941

  18. Electric current activated/assisted sintering (ECAS): a review of patents 1906–2008

    PubMed Central

    Grasso, Salvatore; Sakka, Yoshio; Maizza, Giovanni

    2009-01-01

    The electric current activated/assisted sintering (ECAS) is an ever growing class of versatile techniques for sintering particulate materials. Despite the tremendous advances over the last two decades in ECASed materials and products there is a lack of comprehensive reviews on ECAS apparatuses and methods. This paper fills the gap by tracing the progress of ECAS technology from 1906 to 2008 and surveys 642 ECAS patents published over more than a century. It is found that the ECAS technology was pioneered by Bloxam (1906 GB Patent No. 9020) who developed the first resistive sintering apparatus. The patents were searched by keywords or by cross-links and were withdrawn from the Japanese Patent Office (342 patents), the United States Patent and Trademark Office (175 patents), the Chinese State Intellectual Property Office of P.R.C. (69 patents) and the World Intellectual Property Organization (12 patents). A subset of 119 (out of 642) ECAS patents on methods and apparatuses was selected and described in detail with respect to their fundamental concepts, physical principles and importance in either present ECAS apparatuses or future ECAS technologies for enhancing efficiency, reliability, repeatability, controllability and productivity. The paper is divided into two parts, the first deals with the basic concepts, features and definitions of basic ECAS and the second analyzes the auxiliary devices/peripherals. The basic ECAS is classified with reference to discharge time (fast and ultrafast ECAS). The fundamental principles and definitions of ECAS are outlined in accordance with the scientific and patent literature. PMID:27877308

  19. Strategic marketing, part 2: the 4 P's of marketing.

    PubMed

    Lexa, Frank James; Berlin, Jonathan

    2006-04-01

    Marketing and branding are critical business functions that are often ignored or misapplied in the health care sector. Radiology professionals are facing unprecedented competition, turf battles, and other pressures. One tool that can help in meeting this onslaught is to improve your marketing efforts. Some of the most expensive mistakes in marketing (medical and otherwise) are caused by not paying attention to the basics. These "rookie" errors can be avoided by a careful review of the 4 key principles of introductory marketing: product, price, placement, and promotion. This article reviews these concepts as they relate to medical marketing.

  20. [Analgesia, sedation and relaxation in the child with mechanical ventilation].

    PubMed

    Valdivielso-Serna, A

    2008-02-01

    The basic concepts of sedation and analgesia and the tools to asses the level of sedation and analgesia are review. The different methods of sedation and the non pharmacological interventions are described. Sedatives, analgesics and muscle relaxants, their pharmacodynamics and pharmacokinetics in children, their indications in specific situations (intubation, pain control, sedation and neuromuscular blocking) are reviewed. The etiology of patient-ventilator asynchrony in ventilated children and how to treat it are analyzed, giving guides of how to adapt sedation to the level of mechanical ventilation therapy. Finally, general recommendations are given for the analgesia and sedation in mechanically ventilated children.

  1. Highlights from the 2017 North American Cystic Fibrosis Conference.

    PubMed

    Martiniano, Stacey L; Toprak, Demet; Ong, Thida; Zemanick, Edith T; Daines, Cori L; Muhlebach, Marianne S; Esther, Charles R; Dellon, Elisabeth P

    2018-04-16

    The 31st annual North American Cystic Fibrosis Conference (NACFC) was held in Indianapolis, IN on November 2-4, 2017. Abstracts of presentations from the conference were published in a supplement to Pediatric Pulmonology [2017; Pediatr Pulmonol Suppl. 52: S1-S776]. The current review summarizes several major topic areas addressed at the conference: the pathophysiology and basic science of cystic fibrosis (CF) lung disease, clinical trials, clinical management issues, and quality improvement (QI). In this review, we describe emerging concepts in several areas of CF research and care. © 2018 Wiley Periodicals, Inc.

  2. Automatic Traffic Advisory and Resolution Service (ATARS) Algorithms Including Resolution-Advisory-Register Logic. Volume 1. Sections 1 through 11,

    DTIC Science & Technology

    1981-06-01

    Donald Roberts contributed to the final design review and editing of this document as well as having overall project and technical management...and Reporting function 7. A Data Extraction function 1-5 2. SYSTEM OVERVIEW The basic concept of ATARS is very briefly reviewed here as background to...8-P30 PRM threatadvisorydeerination; If! ((SVECT1.CUNC 12 %P&LSZ jfl SV2c?t.ITSEQ 11 UNflQ) (SVUCT2.CUNC 12 SPILS2 LU SYICT2.&TS2Q j1, UIZQ)) TRS 2W

  3. Resilience of Historical Urban Multi-ethnic Settlement: Entrepreneurship and Religiosity Concept of Gresik City

    NASA Astrophysics Data System (ADS)

    Ariestadi, Dian; Antariksa; Dwi Wulandari, Lisa; Surjono

    2017-12-01

    Important aspects in continual development include economic and social developments, as well as environment protection. Social development aspect should concern political aspiration and local socio-culture as resilience of their local wisdom features. A review on urban resilience is more focused on economic and physical concepts, without developing the social concept. Objective of the study was to find out the resilience concept of Gresik City, which was the earliest description of a big trade port city in Indonesia, for example, Jakarta, Surabaya, and Semarang. The study applied morphology approach on spatial settings at historical urban multi-ethnic settlement through physical and non-physical observations, as well as validation through historical records and archives. The descriptive analysis of morphological pattern relates to activities on social, economic, and cultural aspects in order to obtain basic concept of social life. Morphological pattern of Gresik, which is dominated by multi-ethnic settlements, such as Arabs, Chinese, ex-Dutch-colonial, and the natives of Javanese and Madurese, has attracted traders from various nations and ethnics. History of the city as the center of Islamic learning and dissemination has formed the public of Gresik to have basic religious life, which is reflected on Islamic rituals. Settlement domination, which functions as household industries, craftsmanship, and small-scale trading, shows that entrepreneurship activities as socio-economy activities have highly supported daily religious ritual activities. Entrepreneurship and religiosity concept, which is formed and developed through long history of Gresik, represent the resilience of multi-ethnic societies at cities along the North Coast of Java.

  4. The Effective Concepts on Students' Understanding of Chemical Reactions and Energy

    ERIC Educational Resources Information Center

    Ayyildiz, Yildizay; Tarhan, Leman

    2012-01-01

    The purpose of this study was to determine the relationship between the basic concepts related to the unit of "Chemical Reactions and Energy" and the sub-concepts underlying for meaningful learning of the unit and to investigate the effectiveness of them on students' learning achievements. For this purpose, the basic concepts of the unit…

  5. Toward a Model of Work-Related Self: A Narrative Review.

    PubMed

    Knez, Igor

    2016-01-01

    Occupational work as personal and social identification can be conceptualized as one of the life goals that we strive for and find meaning in. A basic categorization of the phenomenon of work-related identity is suggested, based on psychological theories of identity, memory and relational schema. It distinguishes between organizational, workgroup and professional identity. The two former relate to the concepts of social identity and collective self and the latter to the concepts of personal identity and individual self. These are assumed to form functionally independent cognitive structures, leading to separate motivations and influences on work-related satisfaction. Given this, empirical research on the impact of work-related identity on employee satisfaction, in general terms, is reviewed. The article concludes with some prospective directions for future research by sketching a general model of work-related self. It is hypothesized to evolve by a causal progression from employment across time via emotional and cognitive components.

  6. Toward a Model of Work-Related Self: A Narrative Review

    PubMed Central

    Knez, Igor

    2016-01-01

    Occupational work as personal and social identification can be conceptualized as one of the life goals that we strive for and find meaning in. A basic categorization of the phenomenon of work-related identity is suggested, based on psychological theories of identity, memory and relational schema. It distinguishes between organizational, workgroup and professional identity. The two former relate to the concepts of social identity and collective self and the latter to the concepts of personal identity and individual self. These are assumed to form functionally independent cognitive structures, leading to separate motivations and influences on work-related satisfaction. Given this, empirical research on the impact of work-related identity on employee satisfaction, in general terms, is reviewed. The article concludes with some prospective directions for future research by sketching a general model of work-related self. It is hypothesized to evolve by a causal progression from employment across time via emotional and cognitive components. PMID:27014140

  7. Consciousness, epilepsy, and emotional qualia.

    PubMed

    Monaco, Francesco; Mula, Marco; Cavanna, Andrea E

    2005-09-01

    The last decade has seen a renaissance of consciousness studies, witnessed by the growing number of scientific investigations on this topic. The concept of consciousness is central in epileptology, despite the methodological difficulties concerning its application to the multifaced ictal phenomenology. The authors provide an up-to-date review of the neurological literature on the relationship between epilepsy and consciousness and propose a bidimensional model (level vs contents of consciousness) for the description of seizure-induced alterations of conscious states, according to the findings of recent neuroimaging studies. The neurophysiological correlates of ictal loss and impairment of consciousness are also reviewed. Special attention is paid to the subjective experiential states associated with medial temporal lobe epilepsy. Such ictal phenomenal experiences are suggested as a paradigm for a neuroscientific approach to the apparently elusive philosophical concept of qualia. Epilepsy is confirmed to represent a privileged window over basic neurobiological mechanisms of consciousness.

  8. Conceptual developments of non-equilibrium statistical mechanics in the early days of Japan

    NASA Astrophysics Data System (ADS)

    Ichiyanagi, Masakazu

    1995-11-01

    This paper reviews the research in nonequilibrium statistical mechanics made in Japan in the period between 1930 and 1960. Nearly thirty years have passed since the discovery of the exact formula for the electrical conductivity. With the rise of the linear response theory, the methods and results of which are quickly grasped by anyone, its rationale was pushed aside and even at the stage where the formulation was still incomplete some authors hurried to make physical applications. Such an attitude robbed it of most of its interest for the average physicist, who would approach an understanding of some basic concept, not through abstract and logical analysis but by simply increasing his technical experiences with the concept. The purpose of this review is to rescue the linear response theory from being labeled a mathematical tool and to show that it has considerable physical content. Many key papers, originally written in Japanese, are reproduced.

  9. Approach to economic evaluation in primary care: review of a useful tool for primary care reform.

    PubMed

    McBrien, Kerry A; Manns, Braden

    2013-06-01

    To present an overview of the methods of economic evaluation in health care, using examples of studies applicable to primary care. The main concepts discussed in this article were derived from expert opinion and substantiated with well respected textbooks and comprehensive Canadian guidelines. Examples of cost-effectiveness estimates were taken from the published literature. We describe the basic principles of economic evaluation and provide an introduction to its interpretation, using examples of studies applicable to primary care. A basic understanding of health economics will allow primary care practitioners to begin to incorporate economic data, including that from economic evaluations when they are available, into resource planning for their practices.

  10. Unders and Overs: Using a Dice Game to Illustrate Basic Probability Concepts

    ERIC Educational Resources Information Center

    McPherson, Sandra Hanson

    2015-01-01

    In this paper, the dice game "Unders and Overs" is described and presented as an active learning exercise to introduce basic probability concepts. The implementation of the exercise is outlined and the resulting presentation of various probability concepts are described.

  11. [Perspectives on body: embodiment and body image].

    PubMed

    Chang, Shiow-Ru; Chao, Yu-Mei Yu

    2007-06-01

    "Body" is a basic concept of both the natural and human sciences. This extensive review of the literature explores the various philosophical approaches to the body, including empiricism, idealism, existentialism and phenomenology, as well as the relationship between body and mind. Embodiment and body image are the two main concepts of body addressed in this article. Merleau-Ponty's perspective on embodiment, an important new area of theory development, emphasizes that embodiment research must focus on life experiences, such as the study of body image. Using Schilder's framework of psychosocialology, this article provides a comprehensive understanding of the concept of body image and women's perspectives on the "body" in both Western culture and Eastern cultures. Body size and shape significantly influence the self-image of women. Body image is something that develops and changes throughout one's life span and is continually being constructed, destructed, and reconstructed. Personal body image has important psychological effects on the individual, especially women. This integrative review can make a significant contribution to knowledge in this area and, consequently, to related practice and research.

  12. The cyclotron maser theory of AKR and Z-mode radiation. [Auroral Kilometric Radiation

    NASA Technical Reports Server (NTRS)

    Wu, C. S.

    1985-01-01

    The cyclotron maser mechanism which may be responsible for the generation of auroral kilometric radiation and Z-mode radiation is discussed. Emphasis is placed on the basic concepts of the cyclotron maser theory, particularly the relativistic effect of the cyclotron resonance condition. Recent development of the theory is reviewed. Finally, the results of a computer simulation study which helps to understand the nonlinear saturation of the maser instability are reported.

  13. AUTOMOTIVE DIESEL MAINTENANCE 1. UNIT XI, PART I--MAINTAINING THE FUEL SYSTEM (PART I), CUMMINS DIESEL ENGINES, PART II--UNIT REPLACEMENT (ENGINE).

    ERIC Educational Resources Information Center

    Human Engineering Inst., Cleveland, OH.

    THIS MODULE OF A 30-MODULE COURSE IS DESIGNED TO DEVELOP AN UNDERSTANDING OF DIFFERENCES BETWEEN TWO AND FOUR CYCLE ENGINES, THE OPERATION AND MAINTENANCE OF THE DIESEL ENGINE FUEL SYSTEM, AND THE PROCEDURES FOR DIESEL ENGINE REMOVAL. TOPICS ARE (1) REVIEW OF TWO CYCLE AND FOUR CYCLE CONCEPT, (2) SOME BASIC CHARACTERISTICS OF FOUR CYCLE ENGINES,…

  14. [Monitorization of respiratory mechanics in the ventilated patient].

    PubMed

    García-Prieto, E; Amado-Rodríguez, L; Albaiceta, G M

    2014-01-01

    Monitoring during mechanical ventilation allows the measurement of different parameters of respiratory mechanics. Accurate interpretation of these data can be useful for characterizing the situation of the different components of the respiratory system, and for guiding ventilator settings. In this review, we describe the basic concepts of respiratory mechanics, their interpretation, and their potential use in fine-tuning mechanical ventilation. Copyright © 2013 Elsevier España, S.L. y SEMICYUC. All rights reserved.

  15. Sector Review: Workshops I and II. Pengian kebijakan, Subsektor Pendidikan, SD dan SMP. East Java Province, West Java Province, South Sulawes Province. Educational Policy and Planning Project.

    ERIC Educational Resources Information Center

    Florida State Univ., Tallahassee. Learning Systems Inst.

    This publication contains the first two of three training workshop manuals designed to be used in conducting an update of the Indonesian Education and Human Resources Sector Assessment. Workshop I covers the basic concepts, skills, and methods needed to design subsector updates and develop a draft plan for update activities. Workshops II and III…

  16. Design and Development of Basic Physical Layer WiMAX Network Simulation Models

    DTIC Science & Technology

    2009-01-01

    Wide Web . The third software version was developed during the period of 22 August to 4 November, 2008. The software version developed during the...researched on the Web . The mathematics of some fundamental concepts such as Fourier transforms, convolutional coding techniques were also reviewed...Mathworks Matlab users’ website. A simulation model was found, entitled Estudio y Simulacion de la capa Jisica de la norma 802.16 ( Sistema WiMAX) developed

  17. Software engineering and the role of Ada: Executive seminar

    NASA Technical Reports Server (NTRS)

    Freedman, Glenn B.

    1987-01-01

    The objective was to introduce the basic terminology and concepts of software engineering and Ada. The life cycle model is reviewed. The application of the goals and principles of software engineering is applied. An introductory understanding of the features of the Ada language is gained. Topics addressed include: the software crises; the mandate of the Space Station Program; software life cycle model; software engineering; and Ada under the software engineering umbrella.

  18. Modular avionics packaging standardization

    NASA Astrophysics Data System (ADS)

    Austin, M.; McNichols, J. K.

    The Modular Avionics Packaging (MAP) Program for packaging future military avionics systems with the objective of improving reliability, maintainability, and supportability, and reducing equipment life cycle costs is addressed. The basic MAP packaging concepts called the Standard Avionics Module, the Standard Enclosure, and the Integrated Rack are summarized, and the benefits of modular avionics packaging, including low risk design, technology independence with common functions, improved maintainability and life cycle costs are discussed. Progress made in MAP is briefly reviewed.

  19. Radiological Dispersion Devices and Basic Radiation Science

    ERIC Educational Resources Information Center

    Bevelacqua, Joseph John

    2010-01-01

    Introductory physics courses present the basic concepts of radioactivity and an overview of nuclear physics that emphasizes the basic decay relationship and the various types of emitted radiation. Although this presentation provides insight into radiological science, it often fails to interest students to explore these concepts in a more rigorous…

  20. Teaching Future Teachers Basic Astronomy Concepts--Sun-Earth-Moon Relative Movements--at a Time of Reform in Science Education

    ERIC Educational Resources Information Center

    Trumper, Ricardo

    2006-01-01

    In view of students' alternative conceptions about basic concepts in astronomy, we conducted a series of constructivist activities with future elementary and junior high school teachers aimed at changing their conceptions about the cause of seasonal changes, and of several characteristics of the Sun-Earth-Moon relative movements like Moon phases,…

  1. The Effect of Using an Educational Website in Achievement of Bachelor Students in the Course of Basic Concepts in Mathematics at Al al-Bayt University

    ERIC Educational Resources Information Center

    Qudah, Ahmad Hassan

    2016-01-01

    The study aimed to detect the effect of using an educational site on the Internet in the collection of bachelor's students in the course of basic concepts in mathematics at Al al-Bayt University, and the study sample consisted of all students in the course basic concepts in mathematics in the first semester of the academic year 2014/2015 and the…

  2. Basic nursing care: retrospective evaluation of communication and psychosocial interventions documented by nurses in the acute care setting.

    PubMed

    Juvé-Udina, Maria-Eulàlia; Pérez, Esperanza Zuriguel; Padrés, Núria Fabrellas; Samartino, Maribel Gonzalez; García, Marta Romero; Creus, Mònica Castellà; Batllori, Núria Vila; Calvo, Cristina Matud

    2014-01-01

    This study aimed to evaluate the frequency of psychosocial aspects of basic nursing care, as e-charted by nurses, when using an interface terminology. An observational, multicentre study was conducted in acute wards. The main outcome measure was the frequency of use of the psychosocial interventions in the electronic nursing care plans, analysed over a 12 month retrospective review. Overall, 150,494 electronic care plans were studied. Most of the intervention concepts from the interface terminology were used by registered nurses to illustrate the psychosocial aspects of fundamentals of care in the electronic care plans. The results presented help to demonstrate that the interventions of this interface terminology may be useful to inform psychosocial aspects of basic and advanced nursing care. The identification of psychosocial elements of basic nursing care in the nursing documentation may lead to obtain a deeper understanding of those caring interventions nurses consider essential to represent nurse-patient interactions. The frequency of psychosocial interventions may contribute to delineate basic and advanced nursing care. © 2013 Sigma Theta Tau International.

  3. [Empowerment in prevention and health promotion--a critical conceptual evaluation of basic understanding, dimensions and assessment problems].

    PubMed

    Kliche, T; Kröger, G

    2008-12-01

    Empowerment is an important concept in health care, but despite its prevalence it seems to be more of a buzz word. Thus, a conceptual review on empowerment in prevention and health promotion was carried out. 62 German and international theoretical contributions, reviews and studies were incorporated, covering the fields of prevention, care and therapy, rehabilitation, health-care research, nursing and work-related stress. The analysis revealed eight main dimensions of empowerment: (1) shared decision-making, (2) self-efficacy, (3) social support and social capital, (4) skills and competences, (5) health care utilisation, (6) goal setting and attainment, (7) reflexive thought and (8) innovation. Their empirical assessment can be carried out on a micro-, meso-, or macro-level. Three distinct basic conceptual notions emerged from the analysis, each applying its own specific research questions and measurement instruments: clinical, organizational-professional and political understanding of "empowerment". Therefore, these three specific conceptual notions should each be developed and tested separately, in particular in reviews, and empirical studies should embrace all eight subdimensions.

  4. Development of a Multi-experience Approach in Introductory Soil and Vegetation Geography Courses.

    ERIC Educational Resources Information Center

    Limbird, Arthur

    1982-01-01

    Describes an introductory college level course in soil and vegetation which uses lecture, audiovisual tutorial, individualized instruction, field trips, films, and games. The course consists of three segments: basic concepts of soils, basic concepts of plants, and soil and vegetation concepts in a spatial context. (KC)

  5. Satellite Ocean Biology: Past, Present, Future

    NASA Technical Reports Server (NTRS)

    McClain, Charles R.

    2012-01-01

    Since 1978 when the first satellite ocean color proof-of-concept sensor, the Nimbus-7 Coastal Zone Color Scanner, was launched, much progress has been made in refining the basic measurement concept and expanding the research applications of global satellite time series of biological and optical properties such as chlorophyll-a concentrations. The seminar will review the fundamentals of satellite ocean color measurements (sensor design considerations, on-orbit calibration, atmospheric corrections, and bio-optical algorithms), scientific results from the Sea-viewing Wide Field-of-view Sensor (SeaWiFS) and Moderate resolution Imaging Spectroradiometer (MODIS) missions, and the goals of future NASA missions such as PACE, the Aerosol, Cloud, Ecology (ACE), and Geostationary Coastal and Air Pollution Events (GeoCAPE) missions.

  6. Why are sex and gender important to basic physiology and translational and individualized medicine?

    PubMed

    Miller, Virginia M

    2014-03-01

    Sex refers to biological differences between men and women. Although sex is a fundamental aspect of human physiology that splits the population in two approximately equal halves, this essential biological variable is rarely considered in the design of basic physiological studies, in translating findings from basic science to clinical research, or in developing personalized medical strategies. Contrary to sex, gender refers to social and cultural factors related to being a man or a woman in a particular historical and cultural context. Unfortunately, gender is often used incorrectly by scientists and clinical investigators as synonymous with sex. This article clarifies the definition of sex and gender and reviews evidence showing how sex and gender interact with each other to influence etiology, presentation of disease, and treatment outcomes. In addition, strategies to improve the inclusion of female and male human beings in preclinical and clinical studies will be presented, and the importance of embedding concepts of sex and gender into postgraduate and medical curricula will be discussed. Also, provided is a list of resources for educators. In the history of medical concepts, physiologists have provided pivotal contributions to understanding health and disease processes. In the future, physiologists should provide the evidence for advancing personalized medicine and for reducing sex and gender disparities in health care.

  7. Why are sex and gender important to basic physiology and translational and individualized medicine?

    PubMed Central

    2014-01-01

    Sex refers to biological differences between men and women. Although sex is a fundamental aspect of human physiology that splits the population in two approximately equal halves, this essential biological variable is rarely considered in the design of basic physiological studies, in translating findings from basic science to clinical research, or in developing personalized medical strategies. Contrary to sex, gender refers to social and cultural factors related to being a man or a woman in a particular historical and cultural context. Unfortunately, gender is often used incorrectly by scientists and clinical investigators as synonymous with sex. This article clarifies the definition of sex and gender and reviews evidence showing how sex and gender interact with each other to influence etiology, presentation of disease, and treatment outcomes. In addition, strategies to improve the inclusion of female and male human beings in preclinical and clinical studies will be presented, and the importance of embedding concepts of sex and gender into postgraduate and medical curricula will be discussed. Also, provided is a list of resources for educators. In the history of medical concepts, physiologists have provided pivotal contributions to understanding health and disease processes. In the future, physiologists should provide the evidence for advancing personalized medicine and for reducing sex and gender disparities in health care. PMID:24414073

  8. Computer Literacy Project. A General Orientation in Basic Computer Concepts and Applications.

    ERIC Educational Resources Information Center

    Murray, David R.

    This paper proposes a two-part, basic computer literacy program for university faculty, staff, and students with no prior exposure to computers. The program described would introduce basic computer concepts and computing center service programs and resources; provide fundamental preparation for other computer courses; and orient faculty towards…

  9. Learning Genetics with Paper Pets

    ERIC Educational Resources Information Center

    Finnerty, Valerie Raunig

    2006-01-01

    By the end of the eighth grade, students are expected to have a basic understanding of the mechanism of basic genetic inheritance. However, these concepts can be difficult to teach. In this article, the author introduces a new learning tool that will help facilitate student learning and enthusiasm to the basic concepts of genetic inheritance. This…

  10. Mental models: a basic concept for human factors design in infection prevention.

    PubMed

    Sax, H; Clack, L

    2015-04-01

    Much of the effort devoted to promoting better hand hygiene is based on the belief that poor hand hygiene reflects poor motivation. We argue, however, that automatic unconscious behaviour driven by 'mental models' is an important contributor to what actually happens. Mental models are concepts of reality--imaginary, often blurred, and sometimes unstable. Human beings use them to reduce mental load and free up capacity in the conscious mind to focus on deliberate activities. They are pragmatic solutions to the complexity of life. Knowledge of such mental processes helps healthcare designers and clinicians overcome barriers to behavioural change. This article reviews the concept of mental models and considers how it can be used to improve hand hygiene and patient safety. Copyright © 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  11. Perioperative goal-directed haemodynamic therapy based on flow parameters: a concept in evolution.

    PubMed

    Meng, L; Heerdt, P M

    2016-12-01

    Haemodynamic management incorporating direct or surrogate stroke volume monitoring has experienced a rapid evolution, because of emergence of the "goal-directed therapy" concept and technological developments aimed at providing a parameter leading to the goal. Nonetheless, consensus on both definitions of the ideal "goal" and strategies for achieving it remain elusive. For this review, we first consider basic physiological and patient monitoring factors relevant to the concept of "fluid responsiveness", and then focus upon randomized controlled trials and meta-analyses involving goal-directed haemodynamic therapy based on various flow parameters. Finally, we discuss the current status of noninvasive methods for monitoring fluid responsiveness. © The Author 2016. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  12. [Biometric bases: basic concepts of probability calculation].

    PubMed

    Dinya, E

    1998-04-26

    The author gives or outline of the basic concepts of probability theory. The bases of the event algebra, definition of the probability, the classical probability model and the random variable are presented.

  13. Identifying Students' Conceptions of Basic Principles in Sequence Stratigraphy

    ERIC Educational Resources Information Center

    Herrera, Juan S.; Riggs, Eric M.

    2013-01-01

    Sequence stratigraphy is a major research subject in the geosciences academia and the oil industry. However, the geoscience education literature addressing students' understanding of the basic concepts of sequence stratigraphy is relatively thin, and the topic has not been well explored. We conducted an assessment of 27 students' conceptions of…

  14. Students' Conceptions of Function Transformation in a Dynamic Mathematical Environment

    ERIC Educational Resources Information Center

    Daher, Wajeeh; Anabousy, Ahlam

    2015-01-01

    The study of function transformations helps students understand the function concept which is a basic and main concept in mathematics, but this study is problematic to school students as well as college students, especially when transformations are performed on non-basic functions. The current research tried to facilitate grade 9 students'…

  15. Outline of Basic Concepts in Anthropology. Publication No. 1.

    ERIC Educational Resources Information Center

    Georgia Univ., Athens. Anthropology Curriculum Project.

    This teaching aid outlines basic anthropological concepts described in the various units of the Anthropology Curriculum Project. The outline of important concepts to be learned is intended to be used by the teacher in conjunction with the other instructional materials in each unit. The introduction defines anthropology, its branches and purposes.…

  16. A Concept Transformation Learning Model for Architectural Design Learning Process

    ERIC Educational Resources Information Center

    Wu, Yun-Wu; Weng, Kuo-Hua; Young, Li-Ming

    2016-01-01

    Generally, in the foundation course of architectural design, much emphasis is placed on teaching of the basic design skills without focusing on teaching students to apply the basic design concepts in their architectural designs or promoting students' own creativity. Therefore, this study aims to propose a concept transformation learning model to…

  17. Driving nanocars and nanomachines at interfaces: From concept of nanoarchitectonics to actual use in world wide race and hand operation

    NASA Astrophysics Data System (ADS)

    Shirai, Yasuhiro; Minami, Kosuke; Nakanishi, Waka; Yonamine, Yusuke; Joachim, Christian; Ariga, Katsuhiko

    2016-11-01

    Nanomachine and molecular machines are state-of-the-art objects in current physics and chemistry. The operation and manufacturing of nanosize machines are top-level technologies that we have desired to accomplish for a long time. There have been extensive attempts to design and synthesize nanomachines. In this paper, we review the these attempts using the concept of nanoarchitectonics toward the design, synthesis, and testing of molecular machinery, especially at interfacial media. In the first half of this review, various historical attempts to design and prepare nanomachines are introduced as well as their operation mechanisms from their basic principles. Furthermore, in order to emphasize the importance and possibilities of this research field, we also give examples of two new challenging topics in the second half of this review: (i) a world wide nanocar race and (ii) new modes of nanomachine operation on water. The nanocar race event involves actual use of nanomachines and will take place in the near future, and nanomachine operation of a dynamic fluidic interface will enable future advances in nanomachine science and technology.

  18. Fiber-Optic Sensors for Measurements of Torsion, Twist and Rotation: A Review.

    PubMed

    Budinski, Vedran; Donlagic, Denis

    2017-02-23

    Optical measurement of mechanical parameters is gaining significant commercial interest in different industry sectors. Torsion, twist and rotation are among the very frequently measured mechanical parameters. Recently, twist/torsion/rotation sensors have become a topic of intense fiber-optic sensor research. Various sensing concepts have been reported. Many of those have different properties and performances, and many of them still need to be proven in out-of-the laboratory use. This paper provides an overview of basic approaches and a review of current state-of-the-art in fiber optic sensors for measurements of torsion, twist and/or rotation.Invited Paper.

  19. Fiber-Optic Sensors for Measurements of Torsion, Twist and Rotation: A Review †

    PubMed Central

    Budinski, Vedran; Donlagic, Denis

    2017-01-01

    Optical measurement of mechanical parameters is gaining significant commercial interest in different industry sectors. Torsion, twist and rotation are among the very frequently measured mechanical parameters. Recently, twist/torsion/rotation sensors have become a topic of intense fiber-optic sensor research. Various sensing concepts have been reported. Many of those have different properties and performances, and many of them still need to be proven in out-of-the laboratory use. This paper provides an overview of basic approaches and a review of current state-of-the-art in fiber optic sensors for measurements of torsion, twist and/or rotation. PMID:28241510

  20. Basic statistics with Microsoft Excel: a review.

    PubMed

    Divisi, Duilio; Di Leonardo, Gabriella; Zaccagna, Gino; Crisci, Roberto

    2017-06-01

    The scientific world is enriched daily with new knowledge, due to new technologies and continuous discoveries. The mathematical functions explain the statistical concepts particularly those of mean, median and mode along with those of frequency and frequency distribution associated to histograms and graphical representations, determining elaborative processes on the basis of the spreadsheet operations. The aim of the study is to highlight the mathematical basis of statistical models that regulate the operation of spreadsheets in Microsoft Excel.

  1. Basic statistics with Microsoft Excel: a review

    PubMed Central

    Di Leonardo, Gabriella; Zaccagna, Gino; Crisci, Roberto

    2017-01-01

    The scientific world is enriched daily with new knowledge, due to new technologies and continuous discoveries. The mathematical functions explain the statistical concepts particularly those of mean, median and mode along with those of frequency and frequency distribution associated to histograms and graphical representations, determining elaborative processes on the basis of the spreadsheet operations. The aim of the study is to highlight the mathematical basis of statistical models that regulate the operation of spreadsheets in Microsoft Excel. PMID:28740690

  2. Interactome Networks and Human Disease

    PubMed Central

    Vidal, Marc; Cusick, Michael E.; Barabási, Albert-László

    2011-01-01

    Complex biological systems and cellular networks may underlie most genotype to phenotype relationships. Here we review basic concepts in network biology, discussing different types of interactome networks and the insights that can come from analyzing them. We elaborate on why interactome networks are important to consider in biology, how they can be mapped and integrated with each other, what global properties are starting to emerge from interactome network models, and how these properties may relate to human disease. PMID:21414488

  3. New silicon cell design concepts for 20 percent AMI efficiency

    NASA Technical Reports Server (NTRS)

    Wolf, M.

    1982-01-01

    The basic design principles for obtaining high efficiency in silicon solar cells are reviewed. They critically involve very long minority carrier lifetimes, not so much to attain high collection efficiency, but primarily for increased output voltages. Minority carrier lifetime, however, is sensitive to radiation damage, and particularly in low resistivity silicon, on which the high efficiency design is based. Radiation resistant space cells will therefore have to follow differing design principles than high efficiency terrestrial cells.

  4. Basic Concepts in Molecular Biology Related to Genetics and Epigenetics.

    PubMed

    Corella, Dolores; Ordovas, Jose M

    2017-09-01

    The observation that "one size does not fit all" for the prevention and treatment of cardiovascular disease, among other diseases, has driven the concept of precision medicine. The goal of precision medicine is to provide the best-targeted interventions tailored to an individual's genome. The human genome is composed of billions of sequence arrangements containing a code that controls how genes are expressed. This code depends on other nonstatic regulators that surround the DNA and constitute the epigenome. Moreover, environmental factors also play an important role in this complex regulation. This review provides a general perspective on the basic concepts of molecular biology related to genetics and epigenetics and a glossary of key terms. Several examples are given of polymorphisms and genetic risk scores related to cardiovascular risk. Likewise, an overview is presented of the main epigenetic regulators, including DNA methylation, methylcytosine-phosphate-guanine-binding proteins, histone modifications, other histone regulations, micro-RNA effects, and additional emerging regulators. One of the greatest challenges is to understand how environmental factors (diet, physical activity, smoking, etc.) could alter the epigenome, resulting in healthy or unhealthy cardiovascular phenotypes. We discuss some gene-environment interactions and provide a methodological overview. Copyright © 2017 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

  5. Understanding modern-day vaccines: what you need to know.

    PubMed

    Vetter, Volker; Denizer, Gülhan; Friedland, Leonard R; Krishnan, Jyothsna; Shapiro, Marla

    2018-03-01

    Vaccines are considered to be one of the greatest public health achievements of the last century. Depending on the biology of the infection, the disease to be prevented, and the targeted population, a vaccine may require the induction of different adaptive immune mechanisms to be effective. Understanding the basic concepts of different vaccines is therefore crucial to understand their mode of action, benefits, risks, and their potential real-life impact on protection. This review aims to provide healthcare professionals with background information about the main vaccine designs and concepts of protection in a simplified way to improve their knowledge and understanding, and increase their confidence in the science of vaccination ( Supplementary Material ). KEY MESSAGE Different vaccine designs, each with different advantages and limitations, can be applied for protection against a particular disease. Vaccines may contain live-attenuated pathogens, inactivated pathogens, or only parts of pathogens and may also contain adjuvants to stimulate the immune responses. This review explains the mode of action, benefits, risks and real-life impact of vaccines by highlighting key vaccine concepts. An improved knowledge and understanding of the main vaccine designs and concepts of protection will help support the appropriate use and expectations of vaccines, increase confidence in the science of vaccination, and help reduce vaccine hesitancy.

  6. Basic Measurement and Related Careers: Level C.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center for Vocational and Technical Education.

    The teaching guide, part of a series of four, consists of learning experiences for use at the levels of grades 3 and 4 in mathematics. It focuses on the basic concepts of measurement and developing measurement skills in the early grades. It progresses to the concept of measurement by comparison and to developing basic volume measurement skills.…

  7. The Effect of Home Related Science Activities on Students' Performance in Basic Science

    ERIC Educational Resources Information Center

    Obomanu, B. J.; Akporehwe, J. N.

    2012-01-01

    Our study investigated the effect of utilizing home related science activities on student's performance in some basic science concepts. The concepts considered were heart energy, ecology and mixtures. The sample consisted of two hundred and forty (240) basic junior secondary two (BJSS11) students drawn from a population of five thousand and…

  8. Machine learning for Big Data analytics in plants.

    PubMed

    Ma, Chuang; Zhang, Hao Helen; Wang, Xiangfeng

    2014-12-01

    Rapid advances in high-throughput genomic technology have enabled biology to enter the era of 'Big Data' (large datasets). The plant science community not only needs to build its own Big-Data-compatible parallel computing and data management infrastructures, but also to seek novel analytical paradigms to extract information from the overwhelming amounts of data. Machine learning offers promising computational and analytical solutions for the integrative analysis of large, heterogeneous and unstructured datasets on the Big-Data scale, and is gradually gaining popularity in biology. This review introduces the basic concepts and procedures of machine-learning applications and envisages how machine learning could interface with Big Data technology to facilitate basic research and biotechnology in the plant sciences. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. Optical Coherence Tomography: Basic Concepts and Applications in Neuroscience Research

    PubMed Central

    2017-01-01

    Optical coherence tomography is a micrometer-scale imaging modality that permits label-free, cross-sectional imaging of biological tissue microstructure using tissue backscattering properties. After its invention in the 1990s, OCT is now being widely used in several branches of neuroscience as well as other fields of biomedical science. This review study reports an overview of OCT's applications in several branches or subbranches of neuroscience such as neuroimaging, neurology, neurosurgery, neuropathology, and neuroembryology. This study has briefly summarized the recent applications of OCT in neuroscience research, including a comparison, and provides a discussion of the remaining challenges and opportunities in addition to future directions. The chief aim of the review study is to draw the attention of a broad neuroscience community in order to maximize the applications of OCT in other branches of neuroscience too, and the study may also serve as a benchmark for future OCT-based neuroscience research. Despite some limitations, OCT proves to be a useful imaging tool in both basic and clinical neuroscience research. PMID:29214158

  10. "Blame" Concept in Phraseology: Cognitive-Semantic Aspect (Based on the French Language)

    ERIC Educational Resources Information Center

    Zalavina, Tatyana Y.; Kisel, Olesya V.

    2016-01-01

    Phraseology is one of the basic and most important objects of study in cognitive linguistics. The article deals with verbal fixed phrases in their correlation with the cognitive structure of knowledge--a concept. The used definitional analysis method to identify the basic notions of the conceptual content of the concept of blame and basic…

  11. Teaching Future Teachers Basic Astronomy Concepts--Seasonal Changes--at a Time of Reform in Science Education

    ERIC Educational Resources Information Center

    Trumper, Ricardo

    2006-01-01

    Bearing in mind students' misconceptions about basic concepts in astronomy, the present study conducted a series of constructivist activities aimed at changing future elementary and junior high school teachers' conceptions about the cause of seasonal changes, and several characteristics of the Sun-Earth-Moon relative movements like Moon phases,…

  12. Determination of Secondary School Students' Cognitive Structure, and Misconception in Ecological Concepts through Word Association Test

    ERIC Educational Resources Information Center

    Yücel, Elif Özata; Özkan, Mulis

    2015-01-01

    In this study, we determined cognitive structures and misconceptions about basic ecological concepts by using "word association" tests on secondary school students, age between 12-14 years. Eighty-nine students participated in this study. Before WAT was generated, basic ecological concepts that take place in the secondary science…

  13. Skeletal muscle is a biological example of a linear electroactive actuator

    NASA Astrophysics Data System (ADS)

    Lieber, Richard L.

    1999-05-01

    Skeletal muscle represents a classic biological example of a structure-function relationship. This paper reviews basic muscle anatomy and demonstrates how molecular motion on the order of nm distances is converted into the macroscopic movements that are possible with skeletal muscle. Muscle anatomy provides a structural basis for understanding the basic mechanical properties of skeletal muscle -- namely, the length-tension relationship and the force-velocity relationships. The length-tension relationship illustrates that muscle force generation is extremely length dependent due to the interdigitation of the contractile filaments. The force-velocity relationship is characterized by a rapid force drop in muscle with increasing shortening velocity and a rapid rise in force when muscles are forced to lengthen. Finally, muscle architecture -- the number and arrangement of muscle fibers -- has a profound effect on the magnitude of muscle force generated and the magnitude of muscle excursion. These concepts demonstrate the elegant manner in which muscle acts as a biologically regenerating linear motor. These concepts can be used in developing artificial muscles as well as in performing surgical reconstructive procedures with various donor muscles.

  14. Recent advances in thermoregulation.

    PubMed

    Tansey, Etain A; Johnson, Christopher D

    2015-09-01

    Thermoregulation is the maintenance of a relatively constant core body temperature. Humans normally maintain a body temperature at 37°C, and maintenance of this relatively high temperature is critical to human survival. This concept is so important that control of thermoregulation is often the principal example cited when teaching physiological homeostasis. A basic understanding of the processes underpinning temperature regulation is necessary for all undergraduate students studying biology and biology-related disciplines, and a thorough understanding is necessary for those students in clinical training. Our aim in this review is to broadly present the thermoregulatory process taking into account current advances in this area. First, we summarize the basic concepts of thermoregulation and subsequently assess the physiological responses to heat and cold stress, including vasodilation and vasoconstriction, sweating, nonshivering thermogenesis, piloerection, shivering, and altered behavior. Current research is presented concerning the body's detection of thermal challenge, peripheral and central thermoregulatory control mechanisms, including brown adipose tissue in adult humans and temperature transduction by the relatively recently discovered transient receptor potential channels. Finally, we present an updated understanding of the neuroanatomic circuitry supporting thermoregulation. Copyright © 2015 The American Physiological Society.

  15. Conceptual Hierarchies in a Flat Attractor Network

    PubMed Central

    O’Connor, Christopher M.; Cree, George S.; McRae, Ken

    2009-01-01

    The structure of people’s conceptual knowledge of concrete nouns has traditionally been viewed as hierarchical (Collins & Quillian, 1969). For example, superordinate concepts (vegetable) are assumed to reside at a higher level than basic-level concepts (carrot). A feature-based attractor network with a single layer of semantic features developed representations of both basic-level and superordinate concepts. No hierarchical structure was built into the network. In Experiment and Simulation 1, the graded structure of categories (typicality ratings) is accounted for by the flat attractor-network. Experiment and Simulation 2 show that, as with basic-level concepts, such a network predicts feature verification latencies for superordinate concepts (vegetable ). In Experiment and Simulation 3, counterintuitive results regarding the temporal dynamics of similarity in semantic priming are explained by the model. By treating both types of concepts the same in terms of representation, learning, and computations, the model provides new insights into semantic memory. PMID:19543434

  16. Towards new understanding of the heart structure and function.

    PubMed

    Torrent-Guasp, Francisco; Kocica, Mladen J; Corno, Antonio F; Komeda, Masashi; Carreras-Costa, Francesc; Flotats, A; Cosin-Aguillar, Juan; Wen, Han

    2005-02-01

    Structure and function in any organ are inseparable categories, both in health and disease. Whether we are ready to accept, or not, many questions in cardiovascular medicine are still pending, due to our insufficient insight in the basic science. Even so, any new concept encounters difficulties, mainly arising from our inert attitude, which may result either in unjustified acceptance or denial. The ventricular myocardial band concept, developed over the last 50 years, has revealed unavoidable coherence and mutual coupling of form and function in the ventricular myocardium. After more than five centuries long debate on macroscopic structure of the ventricular myocardium, this concept has provided a promising ground for its final understanding. Recent validations of the ventricular myocardial band, reviewed here, as well as future research directions that are pointed out, should initiate much wider scientific interest, which would, in turn, lead to reconciliation of some exceeded concepts about developmental, electrical, mechanical and energetical events in human heart. The benefit of this, of course, would be the most evident in the clinical arena.

  17. Teaching Basic Science Environmentally, The Concept: The cell is basic unit of structure of most organisms.

    ERIC Educational Resources Information Center

    Busch, Phyllis S.

    1985-01-01

    Suggests simple ways to introduce students to the concept that the cell is the basic unit of structure of most organisms. Mentions materials for microscope study that are readily available and easy to handle, e.g., membranes from between the scales of the onion bulb, thin-leaved plants, pond water, and pollen. (JHZ)

  18. Ability and Disability in Autism Spectrum Disorder: A Systematic Literature Review Employing the International Classification of Functioning, Disability and Health-Children and Youth Version.

    PubMed

    de Schipper, Elles; Lundequist, Aiko; Coghill, David; de Vries, Petrus J; Granlund, Mats; Holtmann, Martin; Jonsson, Ulf; Karande, Sunil; Robison, John E; Shulman, Cory; Singhal, Nidhi; Tonge, Bruce; Wong, Virginia C N; Zwaigenbaum, Lonnie; Bölte, Sven

    2015-12-01

    This study is the first in a series of four empirical investigations to develop International Classification of Functioning, Disability and Health (ICF) Core Sets for Autism Spectrum Disorder (ASD). The objective was to use a systematic review approach to identify, number, and link functional ability and disability concepts used in the scientific ASD literature to the nomenclature of the ICF-CY (Children and Youth version of the ICF, covering the life span). Systematic searches on outcome studies of ASD were carried out in Medline/PubMed, PsycINFO, ERIC and Cinahl, and relevant functional ability and disability concepts extracted from the included studies. These concepts were then linked to the ICF-CY by two independent researchers using a standardized linking procedure. New concepts were extracted from the studies until saturation of identified ICF-CY categories was reached. Seventy-one studies were included in the final analysis and 2475 meaningful concepts contained in these studies were linked to 146 ICF-CY categories. Of these, 99 categories were considered most relevant to ASD (i.e., identified in at least 5% of the studies), of which 63 were related to Activities and Participation, 28 were related to Body functions, and 8 were related to Environmental factors. The five most frequently identified categories were basic interpersonal interactions (51%), emotional functions (49%), complex interpersonal interactions (48%), attention functions (44%), and mental functions of language (44%). The broad variety of ICF-CY categories identified in this study reflects the heterogeneity of functional differences found in ASD--both with respect to disability and exceptionality--and underlines the potential value of the ICF-CY as a framework to capture an individual's functioning in all dimensions of life. The current results in combination with three additional preparatory studies (expert survey, focus groups, and clinical study) will provide the scientific basis for defining the ICF Core Sets for ASD for multipurpose use in basic and applied research and every day clinical practice of ASD. © 2015 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research.

  19. Irritable Bowel Syndrome: Yoga as Remedial Therapy

    PubMed Central

    Kavuri, Vijaya; Raghuram, Nagarathna; Malamud, Ariel; Selvan, Senthamil R.

    2015-01-01

    Irritable bowel syndrome (IBS) is a group of symptoms manifesting as a functional gastrointestinal (GI) disorder in which patients experience abdominal pain, discomfort, and bloating that is often relieved with defecation. IBS is often associated with a host of secondary comorbidities such as anxiety, depression, headaches, and fatigue. In this review, we examined the basic principles of Pancha Kosha (five sheaths of human existence) concept from an Indian scripture Taittiriya Upanishad and the pathophysiology of a disease from the Yoga approach, Yoga Vasistha's Adhi (originated from mind) and Vyadhi (ailment/disease) concept. An analogy between the age old, the most profound concept of Adhi-Vyadhi, and modern scientific stress-induced dysregulation of brain-gut axis, as it relates to IBS that could pave way for impacting IBS, is emphasized. Based on these perspectives, a plausible Yoga module as a remedial therapy is provided to better manage the primary and secondary symptoms of IBS. PMID:26064164

  20. Fuzzy Hybrid Deliberative/Reactive Paradigm (FHDRP)

    NASA Technical Reports Server (NTRS)

    Sarmadi, Hengameth

    2004-01-01

    This work aims to introduce a new concept for incorporating fuzzy sets in hybrid deliberative/reactive paradigm. After a brief review on basic issues of hybrid paradigm the definition of agent-based fuzzy hybrid paradigm, which enables the agents to proceed and extract their behavior through quantitative numerical and qualitative knowledge and to impose their decision making procedure via fuzzy rule bank, is discussed. Next an example performs a more applied platform for the developed approach and finally an overview of the corresponding agents architecture enhances agents logical framework.

  1. Cancer metabolism: facts, fantasy, and fiction.

    PubMed

    Zu, Xin Lin; Guppy, Michael

    2004-01-16

    The concept of a glycolytic cancer cell was introduced by Warburg over 70 years ago. This perception has since become the rationale that drives a considerable proportion of basic research on cancer, and it influences the current strategies for the diagnosis, monitoring, and treatment of cancer. Here we review the data from the last 40 years on this issue. We conclude that there is no evidence that cancer cells are inherently glycolytic, but that some tumours might indeed be glycolytic in vivo as a result of their hypoxic environment.

  2. Review of the research on “structural bionic” method of large sculpture

    NASA Astrophysics Data System (ADS)

    Yin, Jiang; Yang, Wenchang

    2017-09-01

    This paper presented the basic concept of bionic sculpture and summarized the application status of “structural bionic”theory in large bionic sculpture field. Introduced the development trend and challenges of large bionic sculpture and pointed out that the sculpture's “structural bionic” can bring higher mechanical performance of the new structure and system, The evaluation method and structure design for large bionic sculpture are urgently needed.Finally prospected the market of the large bionic sculpture.

  3. A review of post-nuclear-catastrophe management

    NASA Astrophysics Data System (ADS)

    Nifenecker, Hervé

    2015-07-01

    The purpose of this paper is to make radioactive risk more generally understandable. To that end, we compare it to smoking tobacco. Further, we show that the concept of loss of life expectancy permits a quantitative comparison between various aggressions. The demystification of radioactive risk should lead to basic changes in post-catastrophe management, allowing victims to choose whether or not to leave contaminated areas. A less emotional appreciation of radioactive risks should lead to the adaptation of legal practices when dealing with probabilistic situations.

  4. Recent developments in chaotic dynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ott, E.

    1994-02-01

    Before the relatively recent wide acceptance of the existence of chaotic dynamics, many physicists and engineers were under the impression that simple systems could necessarily only display simple solutions. This feeling had been unintentionally reinforced by conventional college courses which emphasize linear dynamics (partly because that is the only case with nice general solutions). More recently, physical experiments and numerical examples have abundantly demonstrated how wrong this feeling is. A brief review of chaotic dynamics is presented. Topics discussed include basic concepts, recent developments, and applications.

  5. Measures and metrics for software development

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The evaluations of and recommendations for the use of software development measures based on the practical and analytical experience of the Software Engineering Laboratory are discussed. The basic concepts of measurement and system of classification for measures are described. The principal classes of measures defined are explicit, analytic, and subjective. Some of the major software measurement schemes appearing in the literature are derived. The applications of specific measures in a production environment are explained. These applications include prediction and planning, review and assessment, and evaluation and selection.

  6. Damping seals for turbomachinery

    NASA Technical Reports Server (NTRS)

    Vonpragenau, G. L.

    1985-01-01

    Rotor whirl stabilization of high performance turbomachinery which operates at supercritical speed is discussed. Basic whirl driving forces are reviewed. Stabilization and criteria are discussed. Damping seals are offered as a solution to whirl and high vibration problems. Concept, advantages, retrofitting, and limits of damping seals are explained. Dynamic and leakage properties are shown to require a rough stator surface for stability and efficiency. Typical seal characteristics are given for the case of the high pressure oxidizer turbopump of the Space Shuttle. Ways of implementation and bearing load effects are discussed.

  7. Ideas, Concepts, Doctrine: Basic Thinking in the United States Air Force, 1907-1960. Volume 1

    DTIC Science & Technology

    1989-12-01

    SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT Same as Report (SAR) 18. NUMBER OF PAGES 684 19a. NAME OF RESPONSIBLE PERSON a. REPORT...reflect the official policy or position of the Department of Defense or the United States government. This publication has been reviewed by security and...lecture have been cleared with the lecturer, even though they may have been unclassified as to military security . To a man these lecturers have been

  8. A knowledge-based system for controlling automobile traffic

    NASA Technical Reports Server (NTRS)

    Maravas, Alexander; Stengel, Robert F.

    1994-01-01

    Transportation network capacity variations arising from accidents, roadway maintenance activity, and special events as well as fluctuations in commuters' travel demands complicate traffic management. Artificial intelligence concepts and expert systems can be useful in framing policies for incident detection, congestion anticipation, and optimal traffic management. This paper examines the applicability of intelligent route guidance and control as decision aids for traffic management. Basic requirements for managing traffic are reviewed, concepts for studying traffic flow are introduced, and mathematical models for modeling traffic flow are examined. Measures for quantifying transportation network performance levels are chosen, and surveillance and control strategies are evaluated. It can be concluded that automated decision support holds great promise for aiding the efficient flow of automobile traffic over limited-access roadways, bridges, and tunnels.

  9. On the Cost of Big Events: Are Weather-Related Disasters as Bad as Economic Recessions for Health Disparities Related to Drug Use?

    PubMed

    Caiaffa, Waleska Teixeira; Andrade, Roseli Gomes

    2015-01-01

    This commentary reviews two manuscripts about big event empirical data exploring concepts and pathways of drug use and health-related events. Using basic concepts and tools, it proposes a focused framework in order to help comprehension of the multifactorial and multilevel components between macrosocial determinants of health, contextual pathways of drug use and drug-use harm and individual levels in the episode of a big event occurrence. The text also discusses implications of preexisting conditions that may be contributing factors for socially and economically segregated subsets of the population, groups possibly "at risk of risks," meaning unequally exposed to risks that generate exposure to other risks, amplifying preexistent inequities.

  10. [Ideal type and history--a critical review of applied criminology].

    PubMed

    Köchel, Stefan

    2013-01-01

    Applied Criminology describes an established criminological school in the German-speaking area, which was founded by Hans Göppinger and Michael Bock, criminologists at Tübingen, in the 1980s and has meanwhile published a number of comprehensive basic methodological papers. The conceptual centrepiece with interdisciplinary approach is the formation and application of concepts referring to the so-called ideal type, which has been essentially inspired by the epistemology of Max Weber. However, the result of a critical reconstruction of these fundamentals is that the claimed interdisciplinary approach comes into conflict with a second much more phenomenological approach of Applied Criminology which is unable to comply with the political implications of criminological research and thus disavows the necessary historical relationality of the ideal type concepts.

  11. Finance for practicing radiologists.

    PubMed

    Berlin, Jonathan W; Lexa, Frank James

    2005-03-01

    This article reviews basic finance for radiologists. Using the example of a hypothetical outpatient computed tomography center, readers are introduced to the concept of net present value. This concept refers to the current real value of anticipated income in the future, realizing that revenue in the future has less value than it does today. Positive net present value projects add wealth to a practice and should be pursued. The article details how costs and revenues for a hypothetical outpatient computed tomography center are determined and elucidates the difference between fixed costs and variable costs. The article provides readers with the steps used to calculate the break-even volume for an outpatient computed tomography center given situation-specific assumptions regarding staff, equipment lease rates, rent, and third-party payer mix.

  12. [Approach to Evidence-based Medicine Exercises Using Flipped Teaching: Introductory Education for Clinical Practice for 4th-Year Pharmacy Students].

    PubMed

    Onda, Mitsuko; Takagaki, Nobumasa

    2018-01-01

     Osaka University of Pharmaceutical Sciences has included an evidence-based medicine (EBM) exercise in the introductory education for clinical practice for 4th-year pharmacy students since 2015. The purpose of this exercise is to learn the process of practice and basic concepts of EBM, especially to cultivate the practical ability to solve patients' problems and answer their questions. Additionally, in 2016, we have attempted flipped teaching. The students are instructed to review the basic knowledge necessary for active learning in this exercise by watching video teaching materials and to bring reports summarizing the contents on the flipped teaching days. The program includes short lectures [overview of EBM, document retrieval, randomized controlled trials (RCTs), and systematic review], exercises [patient, intervention, comparison, outcome (PICO) structuring, critical appraisal of papers in small groups with tutors], and presentations. The program includes: step 1, PICO structuring based on scenarios; step 2, critical appraisal of English-language papers on RCTs using evaluation worksheets; and step 3, reviewing the results of the PICO exercise with patients. The results of the review are shared among groups through general discussion. In this symposium, I discuss students' attitudes, the effectiveness of small group discussions using flipped teaching, and future challenges to be addressed in this program.

  13. Fundamentals in Biostatistics for Research in Pediatric Dentistry: Part I - Basic Concepts.

    PubMed

    Garrocho-Rangel, J A; Ruiz-Rodríguez, M S; Pozos-Guillén, A J

    The purpose of this report was to provide the reader with some basic concepts in order to better understand the significance and reliability of the results of any article on Pediatric Dentistry. Currently, Pediatric Dentists need the best evidence available in the literature on which to base their diagnoses and treatment decisions for the children's oral care. Basic understanding of Biostatistics plays an important role during the entire Evidence-Based Dentistry (EBD) process. This report describes Biostatistics fundamentals in order to introduce the basic concepts used in statistics, such as summary measures, estimation, hypothesis testing, effect size, level of significance, p value, confidence intervals, etc., which are available to Pediatric Dentists interested in reading or designing original clinical or epidemiological studies.

  14. Eosinophils in mucosal immune responses

    PubMed Central

    Travers, J; Rothenberg, M E

    2015-01-01

    Eosinophils, multifunctional cells that contribute to both innate and adaptive immunity, are involved in the initiation, propagation and resolution of immune responses, including tissue repair. They achieve this multifunctionality by expression of a diverse set of activation receptors, including those that directly recognize pathogens and opsonized targets, and by their ability to store and release preformed cytotoxic mediators that participate in host defense, to produce a variety of de novo pleotropic mediators and cytokines and to interact directly and indirectly with diverse cell types, including adaptive and innate immunocytes and structural cells. Herein, we review the basic biology of eosinophils and then focus on new emerging concepts about their role in mucosal immune homeostasis, particularly maintenance of intestinal IgA. We review emerging data about their development and regulation and describe new concepts concerning mucosal eosinophilic diseases. We describe recently developed therapeutic strategies to modify eosinophil levels and function and provide collective insight about the beneficial and detrimental functions of these enigmatic cells. PMID:25807184

  15. Spinal fusion-hardware construct: Basic concepts and imaging review

    PubMed Central

    Nouh, Mohamed Ragab

    2012-01-01

    The interpretation of spinal images fixed with metallic hardware forms an increasing bulk of daily practice in a busy imaging department. Radiologists are required to be familiar with the instrumentation and operative options used in spinal fixation and fusion procedures, especially in his or her institute. This is critical in evaluating the position of implants and potential complications associated with the operative approaches and spinal fixation devices used. Thus, the radiologist can play an important role in patient care and outcome. This review outlines the advantages and disadvantages of commonly used imaging methods and reports on the best yield for each modality and how to overcome the problematic issues associated with the presence of metallic hardware during imaging. Baseline radiographs are essential as they are the baseline point for evaluation of future studies should patients develop symptoms suggesting possible complications. They may justify further imaging workup with computed tomography, magnetic resonance and/or nuclear medicine studies as the evaluation of a patient with a spinal implant involves a multi-modality approach. This review describes imaging features of potential complications associated with spinal fusion surgery as well as the instrumentation used. This basic knowledge aims to help radiologists approach everyday practice in clinical imaging. PMID:22761979

  16. Adaptive eLearning modules for cytopathology education: A review and approach.

    PubMed

    Samulski, T Danielle; La, Teresa; Wu, Roseann I

    2016-11-01

    Clinical training imposes time and resource constraints on educators and learners, making it difficult to provide and absorb meaningful instruction. Additionally, innovative and personalized education has become an expectation of adult learners. Fortunately, the development of web-based educational tools provides a possible solution to these challenges. Within this review, we introduce the utility of adaptive eLearning platforms in pathology education. In addition to a review of the current literature, we provide the reader with a suggested approach for module creation, as well as a critical assessment of an available platform, based on our experience in creating adaptive eLearning modules for teaching basic concepts in gynecologic cytopathology. Diagn. Cytopathol. 2016;44:944-951. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  17. Defining and incorporating basic nursing care actions into the electronic health record.

    PubMed

    Englebright, Jane; Aldrich, Kelly; Taylor, Cathy R

    2014-01-01

    To develop a definition of basic nursing care for the hospitalized adult patient and drive uptake of that definition through the implementation of an electronic health record. A team of direct care nurses, assisted by subject matter experts, analyzed nursing theory and regulatory requirements related to basic nursing care. The resulting list of activities was coded using the Clinical Care Classification (CCC) system and incorporated into the electronic health record system of a 170-bed community hospital. Nine basic nursing care activities were identified as a result of analyzing nursing theory and regulatory requirements in the framework of a hypothetical "well" patient. One additional basic nursing care activity was identified following the pilot implementation in the electronic health record. The pilot hospital has successfully passed a post-implementation regulatory review with no recommendations related to the documentation of basic patient care. This project demonstrated that it is possible to define the concept of basic nursing care and to distinguish it from the interdisciplinary, problem-focused plan of care. The use of the electronic health record can help clarify, document, and communicate basic care elements and improve uptake among nurses. This project to define basic nursing care activities and incorporate into the electronic health record represents a first step in capturing meaningful data elements. When fully implemented, these data could be translated into knowledge for improving care outcomes and collaborative processes. © 2013 Sigma Theta Tau International.

  18. A Stratified Study of Students' Understanding of Basic Optics Concepts in Different Contexts Using Two-Tier Multiple-Choice Items

    ERIC Educational Resources Information Center

    Chu, Hye-Eun; Treagust, David F.; Chandrasegaran, A. L.

    2009-01-01

    A large scale study involving 1786 year 7-10 Korean students from three school districts in Seoul was undertaken to evaluate their understanding of basic optics concepts using a two-tier multiple-choice diagnostic instrument consisting of four pairs of items, each of which evaluated the same concept in two different contexts. The instrument, which…

  19. Basic autonomy as a fundamental step in the synthesis of life.

    PubMed

    Ruiz-Mirazo, Kepa; Moreno, Alvaro

    2004-01-01

    In the search for the primary roots of autonomy (a pivotal concept in Varela's comprehensive understanding of living beings), the theory of autopoiesis provided an explicit criterion to define minimal life in universal terms, and was taken as a guideline in the research program for the artificial synthesis of biological systems. Acknowledging the invaluable contribution of the autopoietic school to present biological thinking, we offer an alternative way of conceiving the most basic forms of autonomy. We give a bottom-up account of the origins of "self-production" (or self-construction, as we propose to call it), pointing out which are the minimal material and energetic requirements for the constitution of basic autonomous systems. This account is, indeed, committed to the project of developing a general theory of biology, but well grounded in the universal laws of physics and chemistry. We consider that the autopoietic theory was formulated in highly abstract terms and, in order to advance in the implementation of minimal autonomous systems (and, at the same time, make major progress in exploring the origins of life), a more specific characterization of minimal autonomous systems is required. Such a characterization will not be drawn from a review of the autopoietic criteria and terminology (à la Fleischaker) but demands a whole reformulation of the question: a proper naturalization of the concept of autonomy. Finally, we also discuss why basic autonomy, according to our account, is necessary but not sufficient for life, in contrast with Varela's idea that autopoiesis was a necessary and sufficient condition for it.

  20. A brief introduction to probability.

    PubMed

    Di Paola, Gioacchino; Bertani, Alessandro; De Monte, Lavinia; Tuzzolino, Fabio

    2018-02-01

    The theory of probability has been debated for centuries: back in 1600, French mathematics used the rules of probability to place and win bets. Subsequently, the knowledge of probability has significantly evolved and is now an essential tool for statistics. In this paper, the basic theoretical principles of probability will be reviewed, with the aim of facilitating the comprehension of statistical inference. After a brief general introduction on probability, we will review the concept of the "probability distribution" that is a function providing the probabilities of occurrence of different possible outcomes of a categorical or continuous variable. Specific attention will be focused on normal distribution that is the most relevant distribution applied to statistical analysis.

  1. Survival analysis in hematologic malignancies: recommendations for clinicians

    PubMed Central

    Delgado, Julio; Pereira, Arturo; Villamor, Neus; López-Guillermo, Armando; Rozman, Ciril

    2014-01-01

    The widespread availability of statistical packages has undoubtedly helped hematologists worldwide in the analysis of their data, but has also led to the inappropriate use of statistical methods. In this article, we review some basic concepts of survival analysis and also make recommendations about how and when to perform each particular test using SPSS, Stata and R. In particular, we describe a simple way of defining cut-off points for continuous variables and the appropriate and inappropriate uses of the Kaplan-Meier method and Cox proportional hazard regression models. We also provide practical advice on how to check the proportional hazards assumption and briefly review the role of relative survival and multiple imputation. PMID:25176982

  2. Review of phase measuring deflectometry

    DOE PAGES

    Huang, Lei; Idir, Mourad; Zuo, Chao; ...

    2018-04-07

    As a low cost, full-field three-dimensional shape measurement technique with high dynamic range, Phase Measuring Deflectometry (PMD) has been studied and improved to be a simple and effective manner to inspect specular reflecting surfaces. In this review, the fundamental principle and the basic concepts of PMD technique are introduced and followed by a brief overview of its key developments since it was first proposed. In addition, the similarities and differences compared with other related techniques are discussed to highlight the distinguishing features of the PMD technique. In conclusion, we will address the major challenges, the existing solutions and the remainingmore » limitations in this technique to provide some suggestions for potential future investigations.« less

  3. Science& Technology Review November 2003

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McMahon, D

    2003-11-01

    This issue of Science & Technology Review covers the following topics: (1) We Will Always Need Basic Science--Commentary by Tomas Diaz de la Rubia; (2) When Semiconductors Go Nano--experiments and computer simulations reveal some surprising behavior of semiconductors at the nanoscale; (3) Retinal Prosthesis Provides Hope for Restoring Sight--A microelectrode array is being developed for a retinal prosthesis; (4) Maglev on the Development Track for Urban Transportation--Inductrack, a Livermore concept to levitate train cars using permanent magnets, will be demonstrated on a 120-meter-long test track; and (5) Power Plant on a Chip Moves Closer to Reality--Laboratory-designed fuel processor gives powermore » boost to dime-size fuel cell.« less

  4. [Intrinsic motivation: a new direction of understanding and treatment of schizophrenia?].

    PubMed

    Wertman, Maayan; Grunhaus, Leon; Israeli, David

    2013-09-01

    While diagnosing schizophrenia, clinicians focus on feeling the quality and nature of the internal motivation of patients. This motivational quality was theoretically conceptualized by Self Determination Theory (SDT). In this article we will review some of the basics of this theory, which focuses on motivational variables assessing behavior on an internal-external axis. Then, we will review prominent findings in the topic of using SDT concepts for the treatment of schizophrenia. The next stage will include a discussion as to the relationship between intrinsic and extrinsic motivators as well as possible neuroanatomy of these behavioral variables. Finally, directions for research will be offered in the field of schizophrenia diagnosis and treatment.

  5. Orthodontics for the dog. Bite evaluation, basic concepts, and equipment.

    PubMed

    Ross, D L

    1986-09-01

    Evaluation of canine occlusion (an occlusal evaluation table is included), growth patterns of the head, basic concepts of orthodontics such as how teeth move, length of treatment, and limits to movements, and equipment and materials are considered in this article.

  6. Chicano Alternative Education.

    ERIC Educational Resources Information Center

    Galicia, H. Homero; Almaguer, Clementina

    Alternative schooling is challenging some basic notions of curriculum, operation, and structure of traditional schools; it is not challenging the basic concept of schooling. Chicano alternative education, an elusive concept, lacks a precise definition. Chicano alternative schools reflect a vast diversity in structure, focus, and goals. The Chicano…

  7. Spaceborne computer executive routine functional design specification. Volume 2: Computer executive design for space station/base

    NASA Technical Reports Server (NTRS)

    Kennedy, J. R.; Fitzpatrick, W. S.

    1971-01-01

    The computer executive functional system design concepts derived from study of the Space Station/Base are presented. Information Management System hardware configuration as directly influencing the executive design is reviewed. The hardware configuration and generic executive design requirements are considered in detail in a previous report (System Configuration and Executive Requirements Specifications for Reusable Shuttle and Space Station/Base, 9/25/70). This report defines basic system primitives and delineates processes and process control. Supervisor states are considered for describing basic multiprogramming and multiprocessing systems. A high-level computer executive including control of scheduling, allocation of resources, system interactions, and real-time supervisory functions is defined. The description is oriented to provide a baseline for a functional simulation of the computer executive system.

  8. Using Film and Social Media for Successful Earth Science Outreach in Nepal and Indonesia

    NASA Astrophysics Data System (ADS)

    Kerlow, I.

    2016-12-01

    We are using social media effectively to bring a documentary film about earthquakes in Nepal to Nepalese audiences that live in tectonically hazardous areas, and a tsunami preparedness movie to the people of Banda Aceh. The one-week online preview of the Nepali-subtitled version of the movie received over 79,000 post Facebook Likes. The movie makes extensive use of animation techniques in addition to live action to explain basic facts about seismic activity in the Himalaya region and also basic preparedness concepts. This presentation reviews the social media campaign designed and implemented to bring preparedness movies to large local audiences, as well as the development, production, and world distribution of natural hazards documentary films with scientific depth but designed for a mainstream audience.

  9. Segmentation of human brain using structural MRI.

    PubMed

    Helms, Gunther

    2016-04-01

    Segmentation of human brain using structural MRI is a key step of processing in imaging neuroscience. The methods have undergone a rapid development in the past two decades and are now widely available. This non-technical review aims at providing an overview and basic understanding of the most common software. Starting with the basis of structural MRI contrast in brain and imaging protocols, the concepts of voxel-based and surface-based segmentation are discussed. Special emphasis is given to the typical contrast features and morphological constraints of cortical and sub-cortical grey matter. In addition to the use for voxel-based morphometry, basic applications in quantitative MRI, cortical thickness estimations, and atrophy measurements as well as assignment of cortical regions and deep brain nuclei are briefly discussed. Finally, some fields for clinical applications are given.

  10. Introduction to Pharmaceutical Biotechnology, Volume 1; Basic techniques and concepts

    NASA Astrophysics Data System (ADS)

    Bhatia, Saurabh; Goli, Divakar

    2018-05-01

    Animal biotechnology is a broad field including polarities of fundamental and applied research, as well as DNA science, covering key topics of DNA studies and its recent applications. In Introduction to Pharmaceutical Biotechnology, DNA isolation procedures followed by molecular markers and screening methods of the genomic library are explained. Interesting areas like isolation, sequencing and synthesis of genes, with the broader coverage on synthesis of genes, are also described. The book begins with an introduction to biotechnology and its main branches, explaining both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It then moves on to historical development and scope of biotechnology with an overall review of early applications that scientists employed long before the field was defined.

  11. Drugs and aggression.

    PubMed

    Rasia-Filho, Alberto A; Giovenardi, Márcia; de Almeida, Rosa M M

    2008-01-01

    Aggression is conceived as a social behavior that, in conjunct with motor and visceral displays, is related with acts for obtaining a specific goal or is directed against threatening stimuli with the intention of causing harm, either for attack or defense. Here it is reviewed basic concepts and aspects for the classification of aggression, the behavioral displays regarded as aggressive in animal models, the basic neural circuits that are involved to them and the pharmacological approaches involving some neurotransmitters (5-HT, dopamine and GABA) and drugs that can be used to identify the neural basis of aggression and to modulate its expression. Drug patents are referred in the text. Data are based on experiments developed mainly with rodents; however, some research hypotheses that may well give some insights for the clinical sciences in men were also included.

  12. Application of Platelet-Rich Plasma to Disorders of the Knee Joint

    PubMed Central

    Mandelbaum, Bert R.; McIlwraith, C. Wayne

    2013-01-01

    Importance. The promising therapeutic potential and regenerative properties of platelet-rich plasma (PRP) have rapidly led to its widespread clinical use in musculoskeletal injury and disease. Although the basic scientific rationale surrounding PRP products is compelling, the clinical application has outpaced the research. Objective. The purpose of this article is to examine the current concepts around the basic science of PRP application, different preparation systems, and clinical application of PRP in disorders in the knee. Evidence Acquisition. A systematic search of PubMed for studies that evaluated the basic science, preparation and clinical application of platelet concentrates was performed. The search used terms, including platelet-rich plasma or PRP preparation, activation, use in the knee, cartilage, ligament, and meniscus. Studies found in the initial search and related studies were reviewed. Results. A comprehensive review of the literature supports the potential use of PRP both nonoperatively and intraoperatively, but highlights the absence of large clinical studies and the lack of standardization between method, product, and clinical efficacy. Conclusions and Relevance. In addition to the call for more randomized, controlled clinical studies to assess the clinical effect of PRP, at this point, it is necessary to investigate PRP product composition and eventually have the ability to tailor the therapeutic product for specific indications. PMID:26069674

  13. Dual Character Concepts in Social Cognition: Commitments and the Normative Dimension of Conceptual Representation.

    PubMed

    Del Pinal, Guillermo; Reuter, Kevin

    2017-04-01

    The concepts expressed by social role terms such as artist and scientist are unique in that they seem to allow two independent criteria for categorization, one of which is inherently normative (Knobe, Prasada, & Newman, 2013). This study presents and tests an account of the content and structure of the normative dimension of these "dual character concepts." Experiment 1 suggests that the normative dimension of a social role concept represents the commitment to fulfill the idealized basic function associated with the role. Background information can affect which basic function is associated with each social role. However, Experiment 2 indicates that the normative dimension always represents the relevant commitment as an end in itself. We argue that social role concepts represent the commitments to basic functions because that information is crucial to predict the future social roles and role-dependent behavior of others. Copyright © 2016 Cognitive Science Society, Inc.

  14. Basic Science.

    ERIC Educational Resources Information Center

    Mercer County Community Coll., Trenton, NJ.

    Instructional materials are provided for a course that covers basic concepts of physics and chemistry. Designed for use in a workplace literacy project developed by Mercer County Community College (New Jersey) and its partners, the course describes applications of these concepts to real-life situations, with an emphasis on applications of…

  15. The RFET—a reconfigurable nanowire transistor and its application to novel electronic circuits and systems

    NASA Astrophysics Data System (ADS)

    Mikolajick, T.; Heinzig, A.; Trommer, J.; Baldauf, T.; Weber, W. M.

    2017-04-01

    With CMOS scaling reaching physical limits in the next decade, new approaches are required to enhance the functionality of electronic systems. Reconfigurability on the device level promises to realize more complex systems with a lower device count. In the last five years a number of interesting concepts have been proposed to realize such a device level reconfiguration. Among these the reconfigurable field effect transistor (RFET), a device that can be configured between an n-channel and p-channel behavior by applying an electrical signal, can be considered as an end-of-roadmap extension of current technology with only small modifications and even simplifications to the process flow. This article gives a review on the RFET basics and current status. In the first sections state-of-the-art of reconfigurable devices will be summarized and the RFET will be introduced together with related devices based on silicon nanowire technology. The device optimization with respect to device symmetry and performance will be discussed next. The potential of the RFET device technology will then be shown by discussing selected circuit implementations making use of the unique advantages of this device concept. The basic device concept was also extended towards applications in flexible devices and sensors, also extending the capabilities towards so-called More-than-Moore applications where new functionalities are implemented in CMOS-based processes. Finally, the prospects of RFET device technology will be discussed.

  16. Basic Emotions, Natural Kinds, Emotion Schemas, and a New Paradigm.

    PubMed

    Izard, Carroll E

    2007-09-01

    Research on emotion flourishes in many disciplines and specialties, yet experts cannot agree on its definition. Theorists and researchers use the term emotion in ways that imply different processes and meanings. Debate continues about the nature of emotions, their functions, their relations to broad affective dimensions, the processes that activate them, and their role in our daily activities and pursuits. I will address these issues here, specifically in terms of basic emotions as natural kinds, the nature of emotion schemas, the development of emotion-cognition relations that lead to emotion schemas, and discrete emotions in relation to affective dimensions. Finally, I propose a new paradigm that assumes continual emotion as a factor in organizing consciousness and as an influence on mind and behavior. The evidence reviewed suggests that a theory that builds on concepts of both basic emotions and emotion schemas provides a viable research tool and is compatible with more holistic or dimensional approaches. © 2007 Association for Psychological Science.

  17. Communication on SWIPT and EH Using Electromagnetic Behaviour for Power Allocation in Wireless Networks

    NASA Astrophysics Data System (ADS)

    Khan, Sohel Rana; Ajij, Sayyad

    2017-12-01

    This review paper focuses on the basic relations between wireless power transfer, wireless information transfer and combined phenomenon of simultaneous wireless information and power transfer. The authors reviewed and discussed electromagnetic fields behaviour (EMB) for enhancing the power allocation strategies (PAS) in energy harvesting (EH) wireless communication systems. Further, this paper presents relations between Friis transmission equation and Maxwell's equations to be used in propagation models for reduction in specific absorption rate (SAR). This paper provides a review of various methods and concepts reported in earlier works. This paper also reviews Poynting vector and power densities along with boundary conditions for antennas and human body. Finally, this paper explores the usage of electromagnetic behaviour for the possible enhancement in power saving methods for electromagnetic behaviour centered-wireless energy harvesting (EMBC-WEH). At the same time, possibilities of PAS for reduction in SAR are discussed.

  18. Teaching Individuals with Developmental Delays: Basic Intervention Techniques.

    ERIC Educational Resources Information Center

    Lovaas, O. Ivar

    This teaching manual for treatment of children with developmental disabilities is divided into seven sections that address: (1) basic concepts; (2) transition into treatment; (3) early learning concepts; (4) expressive language; (5) strategies for visual learners; (6) programmatic considerations; and (7) organizational and legal issues. Among…

  19. Environmental Education: Back to Basics.

    ERIC Educational Resources Information Center

    Warpinski, Robert

    1984-01-01

    Describes an instructional framework based on concepts of energy, ecosystems, carrying capacity, change, and stewardship. Stresses the importance of determining what is really important (basic) for each student to experience or learn in relation to each concept and grade level. Student-centered learning activities and sample lesson on energy…

  20. Criticality Safety Basics for INL FMHs and CSOs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    V. L. Putman

    2012-04-01

    Nuclear power is a valuable and efficient energy alternative in our energy-intensive society. However, material that can generate nuclear power has properties that require this material be handled with caution. If improperly handled, a criticality accident could result, which could severely harm workers. This document is a modular self-study guide about Criticality Safety Principles. This guide's purpose it to help you work safely in areas where fissionable nuclear materials may be present, avoiding the severe radiological and programmatic impacts of a criticality accident. It is designed to stress the fundamental physical concepts behind criticality controls and the importance of criticalitymore » safety when handling fissionable materials outside nuclear reactors. This study guide was developed for fissionable-material-handler and criticality-safety-officer candidates to use with related web-based course 00INL189, BEA Criticality Safety Principles, and to help prepare for the course exams. These individuals must understand basic information presented here. This guide may also be useful to other Idaho National Laboratory personnel who must know criticality safety basics to perform their assignments safely or to design critically safe equipment or operations. This guide also includes additional information that will not be included in 00INL189 tests. The additional information is in appendices and paragraphs with headings that begin with 'Did you know,' or with, 'Been there Done that'. Fissionable-material-handler and criticality-safety-officer candidates may review additional information at their own discretion. This guide is revised as needed to reflect program changes, user requests, and better information. Issued in 2006, Revision 0 established the basic text and integrated various programs from former contractors. Revision 1 incorporates operation and program changes implemented since 2006. It also incorporates suggestions, clarifications, and additional information from readers and from personnel who took course 00INL189. Revision 1 also completely reorganized the training to better emphasize physical concepts behind the criticality controls that fissionable material handlers and criticality safety officers must understand. The reorganization is based on and consistent with changes made to course 00INL189 due to a review of course exam results and to discussions with personnel who conduct area-specific training.« less

  1. Questioning the cerebellar doctrine.

    PubMed

    Galliano, Elisa; De Zeeuw, Chris I

    2014-01-01

    The basic principles of cerebellar function were originally described by Flourens, Cajal, and Marr/Albus/Ito, and they constitute the pillars of what can be considered to be the classic cerebellar doctrine. In their concepts, the main cerebellar function is to control motor behavior, Purkinje cells are the only cortical neuron receiving and integrating inputs from climbing fiber and mossy-parallel fiber pathways, and plastic modification at the parallel fiber synapses onto Purkinje cells constitutes the substrate of motor learning. Yet, because of recent technical advances and new angles of investigation, all pillars of the cerebellar doctrine now face regular re-examination. In this review, after summarizing the classic concepts and recent disputes, we attempt to synthesize an integrated view and propose a revisited version of the cerebellar doctrine. © 2014 Elsevier B.V. All rights reserved.

  2. The implantation of life on Mars - Feasibility and motivation

    NASA Technical Reports Server (NTRS)

    Haynes, Robert H.; Mckay, Christopher P.

    1992-01-01

    Scientific concepts are reviewed regarding the potential formation and development of a life-bearing environment on Mars, and a potential ecopoiesis scenario is given. The development of the earth's biosphere is defined, and the major assumptions related to the formation of Martian life are listed. Three basic phases are described for the life-implantation concept which include determining whether sufficient quantities of volatiles are available, engineering the warming of the planet, and implanting microbial communities if necessary. Warming the planet theoretically releases liquid H2O and produces a thick CO2 atmosphere, and the implantation of biological communities is only necessary if no indigenous microbes emerge. It is concluded that a feasibility study is required to assess the possibilities of implanting life on Mars more concretely.

  3. BOOK REVIEW: Introductory Nanoscience: Physical and Chemical Concepts Introductory Nanoscience: Physical and Chemical Concepts

    NASA Astrophysics Data System (ADS)

    Bich Ha, Nguyen

    2011-12-01

    Having grown rapidly during the last two decades, and successfully synthesized the achievements of physics, chemistry, life science as well as information and computational science and technology, nanoscience and nanotechnology have emerged as interdisciplinary fields of modern science and technology with various prospective applications towards environmental protection and the sustainable development of industry, agriculture, public health etc. At the present time, there exist many textbooks, monographs and encyclopedias on nanoscience and nanotechnology. They present to readers the whole process of development from the emergence of new scientific ideas to comprehensive studies of concrete subjects. They are useful for experienced scientists in nanoscience and nanotechnology as well as related scientific disciplines. However, there are very few textbooks on nanoscience and nanotechnology for beginners—senior undergraduate and junior graduate students. Published by Garland Science in August 2011, Introductory Nanoscience: Physical and Chemical Concepts by Masaru Kuno is one of these rare textbooks. The purpose of this book is twofold. In a pedagogical manner the author presents the basic physical and chemical concepts of nanoscience and nanotechnology. Students with a background knowledge in general chemistry and semiclassical quantum physics can easily understand these concepts. On the other hand, by carefully studying the content of this textbook, readers can learn how to derive a large number of formulae and expressions which they will often use in their study as well as in their future research work. A distinguishing feature of the book is the inclusion of a large number of thought problems at the end of each chapter for demonstrating how to calculate the numerical values of almost all physical quantities involved in the theoretical and experimental studies of all subjects of nanoscience and nanotechnology. The author has successfully achieved both of the main aims of the textbook. The book consists of 15 chapters. According to their detailed contents they can be divided into three groups. In five chapters forming the first group (Introduction, Structure, Length Scales, Types of Nanostructures, Absorption and Emission Basics) the author presents the notions, definitions and concepts related to nanosystems, as well as the length scales of all their physical parameters. The contents of these chapters have been written for all readers studying any undergraduate academic programme in natural sciences and engineering. The subsequent seven chapters forming the second group (A Quantum Mechanics Review, Model Quantum Mechanics Problems, Additional Model Problems, Density of States, Bands, Time-Dependent Perturbation Theory, Interband Transitions) contain a comprehensive and easily understandable presentation of the theoretical basics of nanoscience. The last three chapters (Synthesis, Characterization, Applications) contain presentations on the fundamental methods in the experimental studies and applications of nanosystems. This book is very useful not only for training beginners in research and engineering in nanoscience and nanotechnology, but also for attracting the interest of specialists in other scientific disciplines to the application of the achievements of this new emerging multidisciplinary scientific field.

  4. Money Matters for the Young Learner

    ERIC Educational Resources Information Center

    Hill, Andrew T.

    2010-01-01

    Children's economic reasoning follows a developmental sequence in which their ideas about money and other basic economic concepts are forming. Even children in the early primary grades can learn some basic economics and retain understanding of economic concepts if they are taught in developmentally appropriate ways. Given how important economic…

  5. ECON 12: Teacher's Materials. Units I and II.

    ERIC Educational Resources Information Center

    Wiggins, Suzanne

    The objectives of this experimental 12th grade economics course begin with an understanding that "economic analysis applies a set of basic concepts and their interrelationships to problems (involving) economic scarcity." Fifteen basic concepts are to be learned (e. g., want, markets, money, etc.) as well as the definition and vocabulary…

  6. Teaching Young Children Basic Concepts of Geography: A Literature-Based Approach.

    ERIC Educational Resources Information Center

    Hannibal, Mary Anne Zeitler; Vasiliev, Ren; Lin, Qiuyun

    2002-01-01

    This article advocates a literature-based instructional approach as a way of promoting geographic awareness in early childhood classrooms. Instruction focuses on basic geography concepts of location, place, human- environment interaction, movement, and region. Examples of children's picture books are included to show what early childhood teachers…

  7. Lifeline: A Tool for Logistics Professionals

    DTIC Science & Technology

    2017-06-01

    proof of concept study is designed to provide a basic understanding of the Supply Corps community, provide a comparative analysis of the organizational...concept study is designed to provide a basic understanding of the Supply Corps community, provide a comparative analysis of the organizational...APPLICATION) ......................................................................................63  G.  DESIGN

  8. Basic Concepts and Conservation Skill Training in Kindergarten Chilren.

    ERIC Educational Resources Information Center

    Wasik, Barbara H.; And Others

    1980-01-01

    The study investigated the effects of basic concepts training on conservation acquisition in 41 kindergarten children (17 White boys, 15 White girls, 6 Black girls, and 5 Black boys). Only the conservation training program resulted in significant effects, and that was for the White students alone. (Author)

  9. Basic College-Level Pharmacology: Therapeutic Drug Range Lesson Plan.

    ERIC Educational Resources Information Center

    Laipply, Richelle S.

    2000-01-01

    Investigations of scientific concepts using inquiry can be included in the traditional college lecture. This lesson uses the Learning Cycle to demonstrate therapeutic drug range, a basic concept in pharmaceutical science. Students use graphing to discover patterns as a part of data analysis and interpretation of provided investigation data.…

  10. Econosense: A Common Sense Approach to the Study of Economics.

    ERIC Educational Resources Information Center

    McPheron, Linda

    This student activity book and teacher's guide address specific economic terms and concepts correlated to specific student learning objectives. The concepts presented are those essential to any student developing a basic understanding of economics. Each lesson follows a specific format with a basic core of information, comprehension questions,…

  11. Basic Concepts of Intercultural Communication: Selected Readings.

    ERIC Educational Resources Information Center

    Bennett, Milton J., Ed.

    This collection of articles, with a developmental learning focus, explores the core building blocks of intercultural communication. The articles in the collection represent the theory-into-practice school of intercultural communication. The collection's goal is to present basic concepts from a variety of perspectives which, when taken together,…

  12. Using a Self-Administered Visual Basic Software Tool To Teach Psychological Concepts.

    ERIC Educational Resources Information Center

    Strang, Harold R.; Sullivan, Amie K.; Schoeny, Zahrl G.

    2002-01-01

    Introduces LearningLinks, a Visual Basic software tool that allows teachers to create individualized learning modules that use constructivist and behavioral learning principles. Describes field testing of undergraduates at the University of Virginia that tested a module designed to improve understanding of the psychological concepts of…

  13. This Is Rocket Science!

    NASA Astrophysics Data System (ADS)

    Keith, Wayne; Martin, Cynthia; Veltkamp, Pamela

    2013-09-01

    Using model rockets to teach physics can be an effective way to engage students in learning. In this paper, we present a curriculum developed in response to an expressed need for helping high school students review physics equations in preparation for a state-mandated exam. This required a mode of teaching that was more advanced and analytical than that offered by Estes Industries, but more basic than the analysis of Nelson et al. In particular, drag is neglected until the very end of the exercise, which allows the concept of conservation of energy to be shown when predicting the rocket's flight. Also, the variable mass of the rocket motor is assumed to decrease linearly during the flight (while the propulsion charge and recovery delay charge are burning) and handled simplistically by using an average mass value. These changes greatly simplify the equations needed to predict the times and heights at various stages of flight, making it more useful as a review of basic physics. Details about model rocket motors, range safety, and other supplemental information may be found online at Apogee Components4 and the National Association of Rocketry.5

  14. From stem to roots: Tissue engineering in endodontics

    PubMed Central

    Kala, M.; Banthia, Priyank; Banthia, Ruchi

    2012-01-01

    The vitality of dentin-pulp complex is fundamental to the life of tooth and is a priority for targeting clinical management strategies. Loss of the tooth, jawbone or both, due to periodontal disease, dental caries, trauma or some genetic disorders, affects not only basic mouth functions but aesthetic appearance and quality of life. One novel approach to restore tooth structure is based on biology: regenerative endodontic procedure by application of tissue engineering. Regenerative endodontics is an exciting new concept that seeks to apply the advances in tissue engineering to the regeneration of the pulp-dentin complex. The basic logic behind this approach is that patient-specific tissue-derived cell populations can be used to functionally replace integral tooth tissues. The development of such ‘test tube teeth’ requires precise regulation of the regenerative events in order to achieve proper tooth size and shape, as well as the development of new technologies to facilitate these processes. This article provides an extensive review of literature on the concept of tissue engineering and its application in endodontics, providing an insight into the new developmental approaches on the horizon. Key words:Regenerative, tissue engineering, stem cells, scaffold. PMID:24558528

  15. Engineering of superconductors and superconducting devices using artificial pinning sites

    NASA Astrophysics Data System (ADS)

    Wördenweber, Roger

    2017-08-01

    Vortex matter in superconducting films and devices is not only an interesting topic for basic research but plays a substantial role in the applications of superconductivity in general. We demonstrate, that in most electronic applications, magnetic flux penetrates the superconductor and affects the performance of superconducting devices. Therefore, vortex manipulation turns out to be a useful tool to avoid degradation of superconducting device properties. Moreover, it can also be used to analyze and understand novel and interesting physical properties and develop new concepts for superconductor applications. In this review, various concepts for vortex manipulation are sketched. For example, the use of micro- and nanopatterns (especially, antidots) for guiding and trapping of vortices in superconducting films and thin film devices is discussed and experimental evidence of their vortex guidance and vortex trapping by various arrangements of antidots is given. We demonstrate, that the vortex state of matter is very important in applications of superconductivity. A better understanding does not only lead to an improvement of the performance of superconductor components, such as reduced noise, better power handling capability, or improved reliability, it also promises deeper insight into the basic physics of vortices and vortex matter.

  16. A Detailed Historical Review of Propellant Management Devices for Low Gravity Propellant Acquisition

    NASA Technical Reports Server (NTRS)

    Hartwig, Jason W.

    2016-01-01

    This paper presents a comprehensive background and historical review of Propellant Management Devices (PMDs) used throughout spaceflight history. The purpose of a PMD is to separate liquid and gas phases within a propellant tank and to transfer vapor-free propellant from a storage tank to a transfer line en route to either an engine or receiver depot tank, in any gravitational or thermal environment. The design concept, basic flow physics, and principle of operation are presented for each type of PMD. The three primary capillary driven PMD types of vanes, sponges, and screen channel liquid acquisition devices are compared and contrasted. For each PMD type, a detailed review of previous applications using storable propellants is given, which include space experiments as well as space missions and vehicles. Examples of previous cryogenic propellant management are also presented.

  17. Dielectric Spectroscopy in Biomaterials: Agrophysics

    PubMed Central

    El Khaled, Dalia; Castellano, Nuria N.; Gázquez, Jose A.; Perea-Moreno, Alberto-Jesus; Manzano-Agugliaro, Francisco

    2016-01-01

    Being dependent on temperature and frequency, dielectric properties are related to various types of food. Predicting multiple physical characteristics of agri-food products has been the main objective of non-destructive assessment possibilities executed in many studies on horticultural products and food materials. This review manipulates the basic fundamentals of dielectric properties with their concepts and principles. The different factors affecting the behavior of dielectric properties have been dissected, and applications executed on different products seeking the characterization of a diversity of chemical and physical properties are all pointed out and referenced with their conclusions. Throughout the review, a detailed description of the various adopted measurement techniques and the mostly popular equipment are presented. This compiled review serves in coming out with an updated reference for the dielectric properties of spectroscopy that are applied in the agrophysics field. PMID:28773438

  18. Cloud manufacturing: from concept to practice

    NASA Astrophysics Data System (ADS)

    Ren, Lei; Zhang, Lin; Tao, Fei; Zhao, Chun; Chai, Xudong; Zhao, Xinpei

    2015-02-01

    The concept of cloud manufacturing is emerging as a new promising manufacturing paradigm, as well as a business model, which is reshaping the service-oriented, highly collaborative, knowledge-intensive and eco-efficient manufacturing industry. However, the basic concepts about cloud manufacturing are still in discussion. Both academia and industry will need to have a commonly accepted definition of cloud manufacturing, as well as further guidance and recommendations on how to develop and implement cloud manufacturing. In this paper, we review some of the research work and clarify some fundamental terminologies in this field. Further, we developed a cloud manufacturing systems which may serve as an application example. From a systematic and practical perspective, the key requirements of cloud manufacturing platforms are investigated, and then we propose a cloud manufacturing platform prototype, MfgCloud. Finally, a public cloud manufacturing system for small- and medium-sized enterprises (SME) is presented. This paper presents a new perspective for cloud manufacturing, as well as a cloud-to-ground solution. The integrated solution proposed in this paper, including the terminology, MfgCloud, and applications, can push forward this new paradigm from concept to practice.

  19. When cloud computing meets bioinformatics: a review.

    PubMed

    Zhou, Shuigeng; Liao, Ruiqi; Guan, Jihong

    2013-10-01

    In the past decades, with the rapid development of high-throughput technologies, biology research has generated an unprecedented amount of data. In order to store and process such a great amount of data, cloud computing and MapReduce were applied to many fields of bioinformatics. In this paper, we first introduce the basic concepts of cloud computing and MapReduce, and their applications in bioinformatics. We then highlight some problems challenging the applications of cloud computing and MapReduce to bioinformatics. Finally, we give a brief guideline for using cloud computing in biology research.

  20. Structure-based drug design: docking and scoring.

    PubMed

    Kroemer, Romano T

    2007-08-01

    This review gives an introduction into ligand - receptor docking and illustrates the basic underlying concepts. An overview of different approaches and algorithms is provided. Although the application of docking and scoring has led to some remarkable successes, there are still some major challenges ahead, which are outlined here as well. Approaches to address some of these challenges and the latest developments in the area are presented. Some aspects of the assessment of docking program performance are discussed. A number of successful applications of structure-based virtual screening are described.

  1. Fluorescence microscopy.

    PubMed

    Sanderson, Michael J; Smith, Ian; Parker, Ian; Bootman, Martin D

    2014-10-01

    Fluorescence microscopy is a major tool with which to monitor cell physiology. Although the concepts of fluorescence and its optical separation using filters remain similar, microscope design varies with the aim of increasing image contrast and spatial resolution. The basics of wide-field microscopy are outlined to emphasize the selection, advantages, and correct use of laser scanning confocal microscopy, two-photon microscopy, scanning disk confocal microscopy, total internal reflection, and super-resolution microscopy. In addition, the principles of how these microscopes form images are reviewed to appreciate their capabilities, limitations, and constraints for operation. © 2014 Cold Spring Harbor Laboratory Press.

  2. Management of raised intracranial pressure and hyperosmolar therapy.

    PubMed

    Ropper, Allan H

    2014-06-01

    The management of raised intracranial pressure is undergoing rapid change. The choice of medical treatments to reduce intracranial pressure varies between institutions and regions of the world. The mainstay of therapy, however, continues to be the infusion of a hyperosmolar solution to achieve an osmotic gradient to force the exit of water from the brain. This review introduces the basic concepts of raised intracranial pressure, summarises several recent studies that have challenged dogma in the field, and provides practical advice on hyperosmolar treatment, based on personal experience and a critical reading of the literature.

  3. MODIS: Moderate-resolution imaging spectrometer. Earth observing system, volume 2B

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The Moderate-Resolution Imaging Spectrometer (MODIS), as presently conceived, is a system of two imaging spectroradiometer components designed for the widest possible applicability to research tasks that require long-term (5 to 10 years), low-resolution (52 channels between 0.4 and 12.0 micrometers) data sets. The system described is preliminary and subject to scientific and technological review and modification, and it is anticipated that both will occur prior to selection of a final system configuration; however, the basic concept outlined is likely to remain unchanged.

  4. Thermal infrared remote sensing of surface features for renewable resource applications

    NASA Technical Reports Server (NTRS)

    Welker, J. E.

    1981-01-01

    The subjects of infrared remote sensing of surface features for renewable resource applications is reviewed with respect to the basic physical concepts involved at the Earth's surface and up through the atmosphere, as well as the historical development of satellite systems which produce such data at increasingly greater spatial resolution. With this general background in hand, the growth of a variety of specific renewable resource applications using the developing thermal infrared technology are discussed, including data from HCMM investigators. Recommendations are made for continued growth in this field of applications.

  5. Topological antiferromagnetic spintronics

    NASA Astrophysics Data System (ADS)

    Šmejkal, Libor; Mokrousov, Yuriy; Yan, Binghai; MacDonald, Allan H.

    2018-03-01

    The recent demonstrations of electrical manipulation and detection of antiferromagnetic spins have opened up a new chapter in the story of spintronics. Here, we review the emerging research field that is exploring the links between antiferromagnetic spintronics and topological structures in real and momentum space. Active topics include proposals to realize Majorana fermions in antiferromagnetic topological superconductors, to control topological protection and Dirac points by manipulating antiferromagnetic order parameters, and to exploit the anomalous and topological Hall effects of zero-net-moment antiferromagnets. We explain the basic concepts behind these proposals, and discuss potential applications of topological antiferromagnetic spintronics.

  6. Neuropsychiatric conditions associated with anesthesia exposure.

    PubMed

    Gross, Anne F; Stern, Theodore A

    2014-01-01

    Although anesthetics have been used for more than a century, their mechanisms of action remain poorly understood. Given that a number of intraoperative and postoperative neuropsychiatric syndromes have been linked to the use of anesthetics, practitioners should familiarize themselves with these conditions. Basic concepts about anesthesia are reviewed and neuropsychiatric syndromes associated with anesthesia exposure described. Emergence delirium, postoperative delirium, postoperative cognitive dysfunction, and intraoperative awareness can develop in association with use of inhalation anesthetics and intravenously administered anesthetics. Copyright © 2014 The Academy of Psychosomatic Medicine. Published by Elsevier Inc. All rights reserved.

  7. Geometry and physics of pseudodifferential operators on manifolds

    NASA Astrophysics Data System (ADS)

    Esposito, Giampiero; Napolitano, George M.

    2016-09-01

    A review is made of the basic tools used in mathematics to define a calculus for pseudodifferential operators on Riemannian manifolds endowed with a connection: existence theorem for the function that generalizes the phase; analogue of Taylor's theorem; torsion and curvature terms in the symbolic calculus; the two kinds of derivative acting on smooth sections of the cotangent bundle of the Riemannian manifold; the concept of symbol as an equivalence class. Physical motivations and applications are then outlined, with emphasis on Green functions of quantum field theory and Parker's evaluation of Hawking radiation.

  8. Fluorescence Microscopy

    PubMed Central

    Sanderson, Michael J.; Smith, Ian; Parker, Ian; Bootman, Martin D.

    2016-01-01

    Fluorescence microscopy is a major tool with which to monitor cell physiology. Although the concepts of fluorescence and its optical separation using filters remain similar, microscope design varies with the aim of increasing image contrast and spatial resolution. The basics of wide-field microscopy are outlined to emphasize the selection, advantages, and correct use of laser scanning confocal microscopy, two-photon microscopy, scanning disk confocal microscopy, total internal reflection, and super-resolution microscopy. In addition, the principles of how these microscopes form images are reviewed to appreciate their capabilities, limitations, and constraints for operation. PMID:25275114

  9. Diagnostic devices for isothermal nucleic acid amplification.

    PubMed

    Chang, Chia-Chen; Chen, Chien-Cheng; Wei, Shih-Chung; Lu, Hui-Hsin; Liang, Yang-Hung; Lin, Chii-Wann

    2012-01-01

    Since the development of the polymerase chain reaction (PCR) technique, genomic information has been retrievable from lesser amounts of DNA than previously possible. PCR-based amplifications require high-precision instruments to perform temperature cycling reactions; further, they are cumbersome for routine clinical use. However, the use of isothermal approaches can eliminate many complications associated with thermocycling. The application of diagnostic devices for isothermal DNA amplification has recently been studied extensively. In this paper, we describe the basic concepts of several isothermal amplification approaches and review recent progress in diagnostic device development.

  10. Satellite Power System. Concept development and evaluation program, volume 6: Construction and operations

    NASA Technical Reports Server (NTRS)

    Benson, H.; Jenkins, L. M.

    1981-01-01

    The construction, operation, and maintenance requirements for a solar power satellite, including the space and ground systems, are reviewed. The basic construction guidelines are explained, and construction location options are discussed. The space construction tasks, equipment, and base configurations are discussed together with the operations required to place a solar power satellite in geosynchronous orbit. A rectenna construction technique is explained, and operation with the grid is defined. Maintenance requirements are summarized for the entire system. Key technology issues required for solar power satellite construction operations are defined.

  11. NANOPARTICLES AND THEIR APPLICATIONS IN CELL AND MOLECULAR BIOLOGY

    PubMed Central

    Wang, Edina C.; Wang, Andrew Z.

    2013-01-01

    Nanoparticles can be engineered with distinctive compositions, sizes, shapes, and surface chemistries to enable novel techniques in a wide range of biological applications. The unique properties of nanoparticles and their behavior in biological milieu also enable exciting and integrative approaches to studying fundamental biological questions. This review will provide an overview of various types of nanoparticles and concepts of targeting nanoparticles. We will also discuss the advantages and recent applications of using nanoparticles as tools for drug delivery, imaging, sensing, and for the understanding of basic biological processes. PMID:24104563

  12. Adamantane in Drug Delivery Systems and Surface Recognition.

    PubMed

    Štimac, Adela; Šekutor, Marina; Mlinarić-Majerski, Kata; Frkanec, Leo; Frkanec, Ruža

    2017-02-16

    The adamantane moiety is widely applied in design and synthesis of new drug delivery systems and in surface recognition studies. This review focuses on liposomes, cyclodextrins, and dendrimers based on or incorporating adamantane derivatives. Our recent concept of adamantane as an anchor in the lipid bilayer of liposomes has promising applications in the field of targeted drug delivery and surface recognition. The results reported here encourage the development of novel adamantane-based structures and self-assembled supramolecular systems for basic chemical investigations as well as for biomedical application.

  13. Diagnostic Devices for Isothermal Nucleic Acid Amplification

    PubMed Central

    Chang, Chia-Chen; Chen, Chien-Cheng; Wei, Shih-Chung; Lu, Hui-Hsin; Liang, Yang-Hung; Lin, Chii-Wann

    2012-01-01

    Since the development of the polymerase chain reaction (PCR) technique, genomic information has been retrievable from lesser amounts of DNA than previously possible. PCR-based amplifications require high-precision instruments to perform temperature cycling reactions; further, they are cumbersome for routine clinical use. However, the use of isothermal approaches can eliminate many complications associated with thermocycling. The application of diagnostic devices for isothermal DNA amplification has recently been studied extensively. In this paper, we describe the basic concepts of several isothermal amplification approaches and review recent progress in diagnostic device development. PMID:22969402

  14. Articulation effects in lightness: historical background and theoretical implications.

    PubMed

    Gilchrist, Alan L; Annan, Vidal

    2002-01-01

    The concept of articulation was first introduced by Katz [1935 The World of Colour (London: Kegan Paul, Trench, Trubner & Co)] to refer to the degree of complexity within a field. Katz, who created the basic research methods for studying lightness constancy, found that the greater the degree of articulation within a field of illumination, the greater the degree of constancy. Even though this concept has been largely forgotten, there is much empirical evidence for Katz's principle, and the effects on lightness are very strong. However, when articulation is increased within a framework that does not coincide with a region of illumination, constancy is weakened. Kardos (1934 Zeitschrift für Psychologie Ergänzungband 23) advanced the concept of co-determination, according to which the lightness of a surface is determined relative to more than one field of illumination. Gilchrist et al (1999 Psychological Review 106 795-834) argue that the fields concept should be replaced by the more operational frameworks concept and that a wide variety of lightness errors can be explained by a modification of the Katz principle: the greater the articulation within a perceptual framework, the stronger the anchoring of lightness values within that framework.

  15. Proposed BISOL Facility - a Conceptual Design

    NASA Astrophysics Data System (ADS)

    Ye, Yanlin

    2018-05-01

    In China, a new large-scale nuclear-science research facility, namely the "Beijing Isotope-Separation-On-Line neutron-rich beam facility (BISOL)", has been proposed and reviewed by the governmental committees. This facility aims at both basic science and application goals, and is based on a double-driver concept. On the basic science side, the radioactive ion beams produced from the ISOL device, driven by a research reactor or by an intense deuteron-beam ac- celerator, will be used to study the new physics and technologies at the limit of the nuclear stability in the medium mass region. On the other side regarding to the applications, the facility will be devoted to the material research asso- ciated with the nuclear energy system, by using typically the intense neutron beams produced from the deuteron-accelerator driver. The initial design will be outlined in this report.

  16. Bringing culture to basic psychological theory--beyond individualism and collectivism: comment on Oyserman et al. (2002).

    PubMed

    Miller, Joan G

    2002-01-01

    D. Oyserman, H. M. Coon, and M. Kemmelmeir (2002) offered a comprehensive literature review on individualism and collectivism that forwards valuable suggestions for ways to enhance future research conducted within this framework. The author argues that although their criticisms of much contemporary social psychological research on individualism and collectivism are valid, even more fundamental problems need to be recognized as characterizing work within this tradition, such as the insufficiently subtle nature of the views held of culture, the limited attention given to meanings, and the downplaying of contextual variation. The author suggests adopting more nuanced and process-oriented conceptions of culture and more contextually grounded views of its impact on psychological functioning as a way of realizing the promise of cultural psychology to broaden and provide insight into basic psychological theory.

  17. Basic obstetric pharmacology

    PubMed Central

    Zhao, Yang; Hebert, Mary F.; Venkataramanan, Raman

    2017-01-01

    Pregnancy is associated with a variety of physiological changes that can alter the pharmacokinetics and pharmacodynamics of several drugs. However, limited data exists on the pharmacokinetics and pharmacodynamics of the majority of the medications used in pregnancy. In this article, we first describe basic concepts (drug absorption, bioavailability, distribution, metabolism, elimination, and transport) in pharmacokinetics. Then, we discuss several physiological changes that occur during pregnancy that theoretically affect absorption, distribution, metabolism, and elimination. Further, we provide a brief review of the literature on the clinical pharmacokinetic studies performed in pregnant women in recent years. In general, pregnancy increases the clearance of several drugs and correspondingly decreases drug exposure during pregnancy. Based on current drug exposure measurements during pregnancy, alterations in the dose or dosing regimen of certain drugs are essential during pregnancy. More pharmacological studies in pregnant women are needed to optimize drug therapy in pregnancy. PMID:25281357

  18. Airframe Noise Studies: Review and Future Direction

    NASA Technical Reports Server (NTRS)

    Rackl, Robert G.; Miller, Gregory; Guo, Yueping; Yamamoto, Kingo

    2005-01-01

    This report contains the following information: 1) a review of airframe noise research performed under NASA's Advanced Subsonic Transport (AST) program up to the year 2000, 2) a comparison of the year 1992 airframe noise predictions with those using a year 2000 baseline, 3) an assessment of various airframe noise reduction concepts as applied to the year 2000 baseline predictions, and 4) prioritized recommendations for future airframe noise reduction work. NASA's Aircraft Noise Prediction Program was the software used for all noise predictions and assessments. For future work, the recommendations for the immediate future focus on the development of design tools sensitive to airframe noise treatment effects and on improving the basic understanding of noise generation by the landing gear as well as on its reduction.

  19. Tribological systems as applied to aircraft engines

    NASA Technical Reports Server (NTRS)

    Buckley, D. H.

    1985-01-01

    Tribological systems as applied to aircraft are reviewed. The importance of understanding the fundamental concepts involved in such systems is discussed. Basic properties of materials which can be related to adhesion, friction and wear are presented and correlated with tribology. Surface processes including deposition and treatment are addressed in relation to their present and future application to aircraft components such as bearings, gears and seals. Lubrication of components with both liquids and solids is discussed. Advances in both new liquid molecular structures and additives for those structures are reviewed and related to the needs of advanced engines. Solids and polymer composites are suggested for increasing use and ceramic coatings containing fluoride compounds are offered for the extreme temperatures encountered in such components as advanced bearings and seals.

  20. Emotional Response Deficits in Schizophrenia: Insights From Affective Science

    PubMed Central

    Kring, Ann M.; Moran, Erin K.

    2008-01-01

    Our understanding of the emotional features of schizophrenia has benefited greatly from the adoption of methods and theory from the field of affective science. This article covers basic concepts and methods from affective science on the psychological and neural mechanisms contributing to emotions and reviews the ways in which this research has advanced our understanding of emotional response deficits in schizophrenia. We review naturalistic studies and elicitation studies that evoke emotion responses among participants, including emotion expression, experience, and autonomic physiology. We also consider how these emotion response measures correspond to schizophrenia symptoms, and we focus particular attention on the issue of sex differences in emotional responding and how this may influence our understanding emotional functioning among individuals with schizophrenia. PMID:18579556

  1. An aeroelastician's perspective of wind tunnel and flight experiences with active control of structural response and stability

    NASA Technical Reports Server (NTRS)

    Hanson, P. W.

    1984-01-01

    Active controls technology is assessed based on a review of most of the wind-tunnel and flight tests and actual applications of active control concepts since the late sixties. The distinction is made between so-called ""rigid-body'' active control functions and those that involve significant modification of structural elastic response or stability. Both areas are reviewed although the focus is on the latter area. The basic goals and major results of the various studies or applications are summarized, and the anticipated use of active controls on current and near-future research and demonstration aircraft is discussed. Some of the ""holes'' remaining in the feasbility/benefits demonstration of active controls technology are examined.

  2. Three Short Films about Water: Presenting Basic Concepts to Students and Stakeholders

    NASA Astrophysics Data System (ADS)

    Arrigo, J. S.; Hooper, R. P.; Michel, A.; Wilde, P.; Lilienfeld, L.

    2011-12-01

    Three short form (3 - 5 minute) movies were produced for CUAHSI, to convey basic concepts such as a hydrologic budget, stores and fluxes of water, and the flowpaths and residence time of water. The films were originally intended to be used by scientists to explain the concepts behind potential environmental observatories, but evolved into serving a broader purpose. The films combine still photos, satellite images, animation and video clips, and interviews with CUAHSI members explaining hydrologic concepts in simple, accessible terms. In producing these films, we have found the importance of engaging scientists in conversation first, to develop a script around key accessible concepts and relevant information. Film and communication professionals play a critical role in distilling the scientific explanation and concepts into accessible, engaging film material. The films have been widely distributed through CD and online to educators for use in courses. Additionally, they provide a way to engage stakeholders, particularly land owners, by conveying basic concepts that are necessary to understand the hydrologic and earth science foundation of many of today's political and environmental issues. The films can be viewed online at the CUAHSI website, which also contains links to other film related resources and programs.

  3. Pre-Service Teachers' Mental Models of Basic Astronomy Concepts

    ERIC Educational Resources Information Center

    Arslan, A. Saglam; Durikan, U.

    2016-01-01

    The aim of the present study is to determine pre-service teachers' mental models related to basic astronomy concepts. The study was conducted using a survey method with 293 pre-service teachers from 4 different departments; physics education, science education, primary teacher education and early childhood education. An achievement test with…

  4. Pima College Students' Knowledge of Selected Basic Physical Science Concepts.

    ERIC Educational Resources Information Center

    Iadevaia, David G.

    In 1989 a study was conducted at Pima Community College (PCC) to assess students' knowledge of basic physical science concepts. A three-part survey instrument was administered to students in a second semester sociology class, a first semester astronomy class, a second semester Spanish class, and a first semester physics class. The survey…

  5. Spanish Translation and Validation of the Bracken Basic Concept Scale.

    ERIC Educational Resources Information Center

    Bracken, Bruce A; Fouad, Nadya

    1987-01-01

    The Bracken Basic Concept Scale (BBCS) was translated into Spanish, and 32 preschool and primary age bilingual children were assessed in a counter-balanced format with the English and newly translated Spanish forms to assess the adequacy of the translation. Preliminary content validity of the Spanish BBCS was demonstrated. (Author/JAZ)

  6. Multinational Validation of the Spanish Bracken Basic Concept Scale for Cross-Cultural Assessments.

    ERIC Educational Resources Information Center

    Bracken, Bruce A.; And Others

    1990-01-01

    Investigated construct validity of the Spanish translation of the Bracken Basic Concept Scale (BBCS) in Latino children (n=293) including monolingual Spanish-speaking children from Puerto Rico and Venezuela and Spanish-dominant bilingual Latino children from Texas. Results provided support for construct validity of the Spanish version of the…

  7. Introduction to Chemistry for Water and Wastewater Treatment Plant Operators. Water and Wastewater Training Program.

    ERIC Educational Resources Information Center

    South Dakota Dept. of Environmental Protection, Pierre.

    Presented are basic concepts of chemistry necessary for operators who manage drinking water treatment plants and wastewater facilities. It includes discussions of chemical terms and concepts, laboratory procedures for basic analyses of interest to operators, and discussions of appropriate chemical calculations. Exercises are included and answer…

  8. Introduction to Probability, Part 1 - Basic Concepts. Student Text. Revised Edition.

    ERIC Educational Resources Information Center

    Blakeslee, David W.; And Others

    This book is designed to introduce the reader to some fundamental ideas about probability. The mathematical theory of probability plays an increasingly important role in science, government, industry, business, and economics. An understanding of the basic concepts of probability is essential for the study of statistical methods that are widely…

  9. Getting Back to Basics (& Acidics)

    ERIC Educational Resources Information Center

    Rhodes, Sam

    2006-01-01

    This article describes a few novel acid-base experiments intended to introduce students to the basic concepts of acid-base chemistry and provide practical examples that apply directly to the study of biology and the human body. Important concepts such as the reaction between carbon dioxide and water, buffers and protein denaturation, are covered.…

  10. Teacher knowledge of basic language concepts and dyslexia.

    PubMed

    Washburn, Erin K; Joshi, R Malatesha; Binks-Cantrell, Emily S

    2011-05-01

    Roughly one-fifth of the US population displays one or more symptoms of dyslexia: a specific learning disability that affects an individual's ability to process written language. Consequently, elementary school teachers are teaching students who struggle with inaccurate or slow reading, poor spelling, poor writing, and other language processing difficulties. Findings from studies have indicated that teachers lack essential knowledge needed to teach struggling readers, particularly children with dyslexia. However, few studies have sought to assess teachers' knowledge and perceptions about dyslexia in conjunction with knowledge of basic language concepts related to reading instruction. Thus, the purpose of the present study was to examine elementary school teachers' knowledge of basic language concepts and their knowledge and perceptions about dyslexia. Findings from the present study indicated that teachers, on average, were able to display implicit skills related to certain basic language concepts (i.e. syllable counting), but failed to demonstrate explicit knowledge of others (i.e. phonics principles). Also, teachers seemed to hold the common misconception that dyslexia is a visual processing deficit rather than phonological processing deficit. Copyright © 2011 John Wiley & Sons, Ltd.

  11. Maximum Likelihood Estimation with Emphasis on Aircraft Flight Data

    NASA Technical Reports Server (NTRS)

    Iliff, K. W.; Maine, R. E.

    1985-01-01

    Accurate modeling of flexible space structures is an important field that is currently under investigation. Parameter estimation, using methods such as maximum likelihood, is one of the ways that the model can be improved. The maximum likelihood estimator has been used to extract stability and control derivatives from flight data for many years. Most of the literature on aircraft estimation concentrates on new developments and applications, assuming familiarity with basic estimation concepts. Some of these basic concepts are presented. The maximum likelihood estimator and the aircraft equations of motion that the estimator uses are briefly discussed. The basic concepts of minimization and estimation are examined for a simple computed aircraft example. The cost functions that are to be minimized during estimation are defined and discussed. Graphic representations of the cost functions are given to help illustrate the minimization process. Finally, the basic concepts are generalized, and estimation from flight data is discussed. Specific examples of estimation of structural dynamics are included. Some of the major conclusions for the computed example are also developed for the analysis of flight data.

  12. Digital control of highly augmented combat rotorcraft

    NASA Technical Reports Server (NTRS)

    Tischler, Mark B.

    1987-01-01

    Proposed concepts for the next generation of combat helicopters are to be embodied in a complex, highly maneuverable, multiroled vehicle with avionics systems. Single pilot and nap-of-the-Earth operations require handling qualities which minimize the involvement of the pilot in basic stabilization tasks. To meet these requirements will demand a full authority, high-gain, multimode, multiply-redundant, digital flight-control system. The gap between these requirements and current low-authority, low-bandwidth operational rotorcraft flight-control technology is considerable. This research aims at smoothing the transition between current technology and advanced concept requirements. The state of the art of high-bandwidth digital flight-control systems are reviewed; areas of specific concern for flight-control systems of modern combat are exposed; and the important concepts are illustrated in design and analysis of high-gain, digital systems with a detailed case study involving a current rotorcraft system. Approximate and exact methods are explained and illustrated for treating the important concerns which are unique to digital systems.

  13. Adult learning principles for effective teaching in radiology programmes: a review of the literature.

    PubMed

    Arogundade, R A

    2011-01-01

    Adult learning processes of acquisition of new knowledge, behaviours, skills, values or preferences generally occur as part of personal professional development. There is need for radiology residency trainers to understand the basic adult learning principles for effective teaching processes. To review the different adult learning styles, learning theories and educational practice as a guide for radiology residency trainers. Literature materials from journals, web articles and reputable textbooks in the last 20 years on adult learning principles in general and radiology in particular were reviewed. Most medical educators, including radiologists, lack appropriate formal training background in educational practice. The adult residency trainee brings to the learning environment high quantity and quality of experiences and some amount of control. Connection of this rich adult experience base to the learning process requires facilitation and motivation by the radiology educator, who must be familiar with the use of appropriate learning theories and educational practices. there is a general agreement about the content of good practice in adult education but a definite comprehensive list does not seem to exist in the literature. Nonetheless, understanding of the basic adult learning principles would aid the concept of guided training, where the adult residency trainee shoulders the bulk of the training responsibilities of acquisition of knowledge.

  14. Clinical caring science as a scientific discipline.

    PubMed

    Rehnsfeldt, Arne; Arman, Maria; Lindström, Unni Å

    2017-09-01

    Clinical caring science will be described from a theory of science perspective. The aim of this theoretical article to give a comprehensive overview of clinical caring science as a human science-based discipline grounded in a theory of science argumentation. Clinical caring science seeks idiographic or specific variations of the ontology, concepts and theories, formulated by caring science. The rationale is the insight that the research questions do not change when they are addressed in different contexts. The academic subject contains a concept order with ethos concepts, core and basic concepts and practice concepts that unites systematic caring science with clinical caring science. In accordance with a hermeneutic tradition, the idea of the caring act is based on the degree to which the theory base is hermeneutically appropriated by the caregiver. The better the ethos, essential concepts and theories are understood, the better the caring act can be understood. In order to understand the concept order related to clinical caring science, an example is given from an ongoing project in a disaster context. The concept order is an appropriate way of making sense of the essence of clinical caring science. The idea of the concept order is that concepts on all levels need to be united with each other. A research project in clinical caring science can start anywhere on the concept order, either in ethos, core concepts, basic concepts, practice concepts or in concrete clinical phenomena, as long as no parts are locked out of the concept order as an entity. If, for example, research on patient participation as a phenomenon is not related to core and basic concepts, there is a risqué that the research becomes meaningless. © 2016 Nordic College of Caring Science.

  15. The Theory of Localist Representation and of a Purely Abstract Cognitive System: The Evidence from Cortical Columns, Category Cells, and Multisensory Neurons.

    PubMed

    Roy, Asim

    2017-01-01

    The debate about representation in the brain and the nature of the cognitive system has been going on for decades now. This paper examines the neurophysiological evidence, primarily from single cell recordings, to get a better perspective on both the issues. After an initial review of some basic concepts, the paper reviews the data from single cell recordings - in cortical columns and of category-selective and multisensory neurons. In neuroscience, columns in the neocortex (cortical columns) are understood to be a basic functional/computational unit. The paper reviews the fundamental discoveries about the columnar organization and finds that it reveals a massively parallel search mechanism. This columnar organization could be the most extensive neurophysiological evidence for the widespread use of localist representation in the brain. The paper also reviews studies of category-selective cells. The evidence for category-selective cells reveals that localist representation is also used to encode complex abstract concepts at the highest levels of processing in the brain. A third major issue is the nature of the cognitive system in the brain and whether there is a form that is purely abstract and encoded by single cells. To provide evidence for a single-cell based purely abstract cognitive system, the paper reviews some of the findings related to multisensory cells. It appears that there is widespread usage of multisensory cells in the brain in the same areas where sensory processing takes place. Plus there is evidence for abstract modality invariant cells at higher levels of cortical processing. Overall, that reveals the existence of a purely abstract cognitive system in the brain. The paper also argues that since there is no evidence for dense distributed representation and since sparse representation is actually used to encode memories, there is actually no evidence for distributed representation in the brain. Overall, it appears that, at an abstract level, the brain is a massively parallel, distributed computing system that is symbolic. The paper also explains how grounded cognition and other theories of the brain are fully compatible with localist representation and a purely abstract cognitive system.

  16. The Theory of Localist Representation and of a Purely Abstract Cognitive System: The Evidence from Cortical Columns, Category Cells, and Multisensory Neurons

    PubMed Central

    Roy, Asim

    2017-01-01

    The debate about representation in the brain and the nature of the cognitive system has been going on for decades now. This paper examines the neurophysiological evidence, primarily from single cell recordings, to get a better perspective on both the issues. After an initial review of some basic concepts, the paper reviews the data from single cell recordings – in cortical columns and of category-selective and multisensory neurons. In neuroscience, columns in the neocortex (cortical columns) are understood to be a basic functional/computational unit. The paper reviews the fundamental discoveries about the columnar organization and finds that it reveals a massively parallel search mechanism. This columnar organization could be the most extensive neurophysiological evidence for the widespread use of localist representation in the brain. The paper also reviews studies of category-selective cells. The evidence for category-selective cells reveals that localist representation is also used to encode complex abstract concepts at the highest levels of processing in the brain. A third major issue is the nature of the cognitive system in the brain and whether there is a form that is purely abstract and encoded by single cells. To provide evidence for a single-cell based purely abstract cognitive system, the paper reviews some of the findings related to multisensory cells. It appears that there is widespread usage of multisensory cells in the brain in the same areas where sensory processing takes place. Plus there is evidence for abstract modality invariant cells at higher levels of cortical processing. Overall, that reveals the existence of a purely abstract cognitive system in the brain. The paper also argues that since there is no evidence for dense distributed representation and since sparse representation is actually used to encode memories, there is actually no evidence for distributed representation in the brain. Overall, it appears that, at an abstract level, the brain is a massively parallel, distributed computing system that is symbolic. The paper also explains how grounded cognition and other theories of the brain are fully compatible with localist representation and a purely abstract cognitive system. PMID:28261127

  17. Revisiting reflexology: Concept, evidence, current practice, and practitioner training.

    PubMed

    Embong, Nurul Haswani; Soh, Yee Chang; Ming, Long Chiau; Wong, Tin Wui

    2015-10-01

    Reflexology is basically a study of how one part of the human body relates to another part of the body. Reflexology practitioners rely on the reflexes map of the feet and hands to all the internal organs and other human body parts. They believe that by applying the appropriate pressure and massage certain spots on the feet and hands, all other body parts could be energized and rejuvenated. This review aimed to revisit the concept of reflexology and examine its effectiveness, practices, and the training for reflexology practitioners. PubMed, SCOPUS, Google Scholar, and SpringerLink databases were utilized to search the following medical subject headings or keywords: foot massage, reflexology, foot reflexotherapy, reflexological treatment, and zone therapy. The articles published for the last 10 years were included. Previous systematic reviews failed to show concrete evidence for any specific effect of reflexology in any conditions. Due to its non-invasive, non-pharmacological complementary nature, reflexology is widely accepted and anecdotal evidence of positive effect reflexology in a variety of health conditions are available. Adequate training for practitioners is necessary to ensure the consistency of service provided.

  18. Revisiting reflexology: Concept, evidence, current practice, and practitioner training

    PubMed Central

    Embong, Nurul Haswani; Soh, Yee Chang; Ming, Long Chiau; Wong, Tin Wui

    2015-01-01

    Reflexology is basically a study of how one part of the human body relates to another part of the body. Reflexology practitioners rely on the reflexes map of the feet and hands to all the internal organs and other human body parts. They believe that by applying the appropriate pressure and massage certain spots on the feet and hands, all other body parts could be energized and rejuvenated. This review aimed to revisit the concept of reflexology and examine its effectiveness, practices, and the training for reflexology practitioners. PubMed, SCOPUS, Google Scholar, and SpringerLink databases were utilized to search the following medical subject headings or keywords: foot massage, reflexology, foot reflexotherapy, reflexological treatment, and zone therapy. The articles published for the last 10 years were included. Previous systematic reviews failed to show concrete evidence for any specific effect of reflexology in any conditions. Due to its non-invasive, non-pharmacological complementary nature, reflexology is widely accepted and anecdotal evidence of positive effect reflexology in a variety of health conditions are available. Adequate training for practitioners is necessary to ensure the consistency of service provided. PMID:26587391

  19. Space Station Furnace Facility. Volume 2: Requirements definition and conceptual design study

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The Space Station Freedom Furnace (SSFF) Project is divided into two phases: phase 1, a definition study phase, and phase 2, a design and development phase. TBE was awarded a research study entitled, 'Space Station Furnace Facility Requirements Definition and Conceptual Design Study' on June 2, 1989. This report addresses the definition study phase only. Phase 2 is to be complete after completion of phase 1. The contract encompassed a requirements definition study and culminated in hardware/facility conceptual designs and hardware demonstration development models to test these conceptual designs. The study was divided into two parts. Part 1 (the basic part of the effort) encompassed preliminary requirements definition and assessment; conceptional design of the SSFF Core; fabrication of mockups; and preparation for the support of a conceptional design review (CoDR). Part 2 (the optional part of the effort) included detailed definition of the engineering and design requirements, as derived from the science requirements; refinement of the conceptual design of the SSFF Core; fabrication and testing of the 'breadboards' or development models; and preparation for and support of a requirements definition review.

  20. Network analysis for a network disorder: The emerging role of graph theory in the study of epilepsy.

    PubMed

    Bernhardt, Boris C; Bonilha, Leonardo; Gross, Donald W

    2015-09-01

    Recent years have witnessed a paradigm shift in the study and conceptualization of epilepsy, which is increasingly understood as a network-level disorder. An emblematic case is temporal lobe epilepsy (TLE), the most common drug-resistant epilepsy that is electroclinically defined as a focal epilepsy and pathologically associated with hippocampal sclerosis. In this review, we will summarize histopathological, electrophysiological, and neuroimaging evidence supporting the concept that the substrate of TLE is not limited to the hippocampus alone, but rather is broadly distributed across multiple brain regions and interconnecting white matter pathways. We will introduce basic concepts of graph theory, a formalism to quantify topological properties of complex systems that has recently been widely applied to study networks derived from brain imaging and electrophysiology. We will discuss converging graph theoretical evidence indicating that networks in TLE show marked shifts in their overall topology, providing insight into the neurobiology of TLE as a network-level disorder. Our review will conclude by discussing methodological challenges and future clinical applications of this powerful analytical approach. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Vapor-liquid nucleation: the solid touch.

    PubMed

    Yarom, Michal; Marmur, Abraham

    2015-08-01

    Vapor-liquid nucleation is a ubiquitous process that has been widely researched in many disciplines. Yet, case studies are quite scattered in the literature, and the implications of some of its basic concepts are not always clearly stated. This is especially noticeable for heterogeneous nucleation, which involves a solid surface in touch with the liquid and vapor. The current review attempts to offer a comprehensive, though concise, thermodynamic discussion of homogeneous and heterogeneous nucleation in vapor-liquid systems. The fundamental concepts of nucleation are detailed, with emphasis on the role of the chemical potential, and on intuitive explanations whenever possible. We review various types of nucleating systems and discuss the effect of the solid geometry on the characteristics of the new phase formation. In addition, we consider the effect of mixing on the vapor-liquid equilibrium. An interesting sub-case is that of a non-volatile solute that modifies the chemical potential of the liquid, but not of the vapor. Finally, we point out topics that need either further research or more exact, accurate presentation. Copyright © 2014 Elsevier B.V. All rights reserved.

  2. Metamaterials beyond electromagnetism

    NASA Astrophysics Data System (ADS)

    Kadic, Muamer; Bückmann, Tiemo; Schittny, Robert; Wegener, Martin

    2013-12-01

    Metamaterials are rationally designed man-made structures composed of functional building blocks that are densely packed into an effective (crystalline) material. While metamaterials are mostly associated with negative refractive indices and invisibility cloaking in electromagnetism or optics, the deceptively simple metamaterial concept also applies to rather different areas such as thermodynamics, classical mechanics (including elastostatics, acoustics, fluid dynamics and elastodynamics), and, in principle, also to quantum mechanics. We review the basic concepts, analogies and differences to electromagnetism, and give an overview on the current state of the art regarding theory and experiment—all from the viewpoint of an experimentalist. This review includes homogeneous metamaterials as well as intentionally inhomogeneous metamaterial architectures designed by coordinate-transformation-based approaches analogous to transformation optics. Examples are laminates, transient thermal cloaks, thermal concentrators and inverters, ‘space-coiling’ metamaterials, anisotropic acoustic metamaterials, acoustic free-space and carpet cloaks, cloaks for gravitational surface waves, auxetic mechanical metamaterials, pentamode metamaterials (‘meta-liquids’), mechanical metamaterials with negative dynamic mass density, negative dynamic bulk modulus, or negative phase velocity, seismic metamaterials, cloaks for flexural waves in thin plates and three-dimensional elastostatic cloaks.

  3. The general/specific breakdown of semantic memory and the nature of superordinate knowledge: insights from superordinate and basic-level feature norms.

    PubMed

    Marques, J Frederico

    2007-12-01

    The deterioration of semantic memory usually proceeds from more specific to more general superordinate categories, although rarer cases of superordinate knowledge impairment have also been reported. The nature of superordinate knowledge and the explanation of these two semantic impairments were evaluated from the analysis of superordinate and basic-level feature norms. The results show that, in comparison to basic-level concepts, superordinate concepts are not generally less informative and have similar feature distinctiveness and proportion of individual sensory features, but their features are less shared by their members. Results are in accord with explanations based on feature connection weights and/or concept confusability for the superordinate advantage cases. Results especially support an explanation for superordinate impairments in terms of higher semantic control requirements as related to features being less shared between concept members. Implications for patients with semantic impairments are also discussed.

  4. Concept confusion and concept discernment in basic magnetism using analogical reasoning

    NASA Astrophysics Data System (ADS)

    Lemmer, Miriam; Nicodimus Morabe, Olebogeng

    2017-07-01

    Analogical reasoning is central to all learning, whether in daily life situations, in the classroom or while doing research. Although analogies can aid the learning process of making sense of phenomena and understanding new ideas in terms of known ideas, these should be used with care. This article reports a study of the use of analogies and the consequences of this use in the teaching of magnetism with special reference to misconceptions. We begin by identifying concept confusion and associated misconceptions in magnetism due to in-service physics teachers’ spontaneous analogical reasoning. Two analogy-based experiments that can be used to convert such concept confusion to discernment are then described. These experiments focus on understanding basic principles about sources and interactions of magnetic fields and implement the constructivist learning processes of discrimination and generalization. Lastly, recommendations towards reinforcement of conceptual understanding of basic magnetism in its relation to electricity are proposed.

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pin, F.G.

    Outdoor sensor-based operation of autonomous robots has revealed to be an extremely challenging problem, mainly because of the difficulties encountered when attempting to represent the many uncertainties which are always present in the real world. These uncertainties are primarily due to sensor imprecisions and unpredictability of the environment, i.e., lack of full knowledge of the environment characteristics and dynamics. Two basic principles, or philosophies, and their associated methodologies are proposed in an attempt to remedy some of these difficulties. The first principle is based on the concept of ``minimal model`` for accomplishing given tasks and proposes to utilize only themore » minimum level of information and precision necessary to accomplish elemental functions of complex tasks. This approach diverges completely from the direction taken by most artificial vision studies which conventionally call for crisp and detailed analysis of every available component in the perception data. The paper will first review the basic concepts of this approach and will discuss its pragmatic feasibility when embodied in a behaviorist framework. The second principle which is proposed deals with implicit representation of uncertainties using Fuzzy Set Theory-based approximations and approximate reasoning, rather than explicit (crisp) representation through calculation and conventional propagation techniques. A framework which merges these principles and approaches is presented, and its application to the problem of sensor-based outdoor navigation of a mobile robot is discussed. Results of navigation experiments with a real car in actual outdoor environments are also discussed to illustrate the feasibility of the overall concept.« less

  6. Fundamentals of microfluidic cell culture in controlled microenvironments†

    PubMed Central

    Young, Edmond W. K.; Beebe, David J.

    2010-01-01

    Microfluidics has the potential to revolutionize the way we approach cell biology research. The dimensions of microfluidic channels are well suited to the physical scale of biological cells, and the many advantages of microfluidics make it an attractive platform for new techniques in biology. One of the key benefits of microfluidics for basic biology is the ability to control parameters of the cell microenvironment at relevant length and time scales. Considerable progress has been made in the design and use of novel microfluidic devices for culturing cells and for subsequent treatment and analysis. With the recent pace of scientific discovery, it is becoming increasingly important to evaluate existing tools and techniques, and to synthesize fundamental concepts that would further improve the efficiency of biological research at the microscale. This tutorial review integrates fundamental principles from cell biology and local microenvironments with cell culture techniques and concepts in microfluidics. Culturing cells in microscale environments requires knowledge of multiple disciplines including physics, biochemistry, and engineering. We discuss basic concepts related to the physical and biochemical microenvironments of the cell, physicochemical properties of that microenvironment, cell culture techniques, and practical knowledge of microfluidic device design and operation. We also discuss the most recent advances in microfluidic cell culture and their implications on the future of the field. The goal is to guide new and interested researchers to the important areas and challenges facing the scientific community as we strive toward full integration of microfluidics with biology. PMID:20179823

  7. Human Amniotic Membrane-Derived Products in Sports Medicine: Basic Science, Early Results, and Potential Clinical Applications.

    PubMed

    Riboh, Jonathan C; Saltzman, Bryan M; Yanke, Adam B; Cole, Brian J

    2016-09-01

    Amniotic membrane (AM)-derived products have been successfully used in ophthalmology, plastic surgery, and wound care, but little is known about their potential applications in orthopaedic sports medicine. To provide an updated review of the basic science and preclinical and clinical data supporting the use of AM-derived products and to review their current applications in sports medicine. Systematic review. A systematic search of the literature was conducted using the Medline, EMBASE, and Cochrane databases. The search term amniotic membrane was used alone and in conjunction with stem cell, orthopaedic, tissue engineering, scaffold, and sports medicine. The search identified 6870 articles, 80 of which, after screening of the titles and abstracts, were considered relevant to this study. Fifty-five articles described the anatomy, basic science, and nonorthopaedic applications of AM-derived products. Twenty-five articles described preclinical and clinical trials of AM-derived products for orthopaedic sports medicine. Because the level of evidence obtained from this search was not adequate for systematic review or meta-analysis, a current concepts review on the anatomy, physiology, and clinical uses of AM-derived products is presented. Amniotic membranes have many promising applications in sports medicine. They are a source of pluripotent cells, highly organized collagen, antifibrotic and anti-inflammatory cytokines, immunomodulators, and matrix proteins. These properties may make it beneficial when applied as tissue engineering scaffolds, improving tissue organization in healing, and treatment of the arthritic joint. The current body of evidence in sports medicine is heavily biased toward in vitro and animal studies, with little to no human clinical data. Nonetheless, 14 companies or distributors offer commercial AM products. The preparation and formulation of these products alter their biological and mechanical properties, and a thorough understanding of these differences will help guide the use of AM-derived products in sports medicine research. © 2015 The Author(s).

  8. Effects of Concept Mapping Instruction Approach on Students' Achievement in Basic Science

    ERIC Educational Resources Information Center

    Ogonnaya, Ukpai Patricia; Okafor, Gabriel; Abonyi, Okechukwu S.; Ugama, J. O.

    2016-01-01

    The study investigated the effects of concept mapping on students' achievement in basic science. The study was carried out in Ebonyi State of Nigeria. The study employed a quasi-experimental design. Specifically the pretest posttest non-equivalent control group research design was used. The sample was 122 students selected from two secondary…

  9. A Short Test for the Assessment of Basic Knowledge in Psychology

    ERIC Educational Resources Information Center

    Peter, Johannes; Leichner, Nikolas; Mayer, Anne-Kathrin; Krampen, Günter

    2015-01-01

    This paper reports the development of a fixed-choice test for the assessment of basic knowledge in psychology, for use with undergraduate as well as graduate students. Test content is selected based on a core concepts approach and includes a sample of concepts which are indexed most frequently in common introductory psychology textbooks. In a…

  10. Raising native plants in nurseries: basic concepts

    Treesearch

    R. Kasten Dumroese; Thomas D. Landis; Tara Luna

    2012-01-01

    Growing native plants can be fun, challenging, and rewarding. This booklet, particularly the first chapter that introduces important concepts, is for the novice who wants to start growing native plants as a hobby; however, it can also be helpful to someone with a bit more experience who is wondering about starting a nursery. The second chapter provides basic...

  11. Geographies of American Popular Music: Introducing Students to Basic Geographic Concepts

    ERIC Educational Resources Information Center

    McClain, Stephen S.

    2010-01-01

    Popular music can be used to study many subjects and issues related to the social sciences. "Geographies of American Popular Music" was a workshop that not only examined the history and development of select genres of American music, it also introduced students to basic geographic concepts such as the culture hearth and spatial diffusion. Through…

  12. A Framework for Teaching Basic Economic Concepts with Scope and Sequence Guidelines K-12.

    ERIC Educational Resources Information Center

    Saunders, Phillip, Ed.; Gilliard, June V., Ed.

    This publication is an updated, edited merger of two earlier National Council on Economic Education documents: "A Framework for Teaching the Basic Concepts" and "Economics: What and When." The combined publication is designed to aid those who construct curricula or who provide economics instruction in U.S. schools. The book…

  13. The Vital Role of Basic Mathematics in Teaching and Learning the Mole Concept

    ERIC Educational Resources Information Center

    Mehrotra, Alka; Koul, Anjni

    2016-01-01

    This article focuses on the importance of activity-based teaching in understanding the mole concept and the vital role of basic mathematical operations. It describes needs-based training for teachers in a professional development programme in India. Analysis of test results before and after the training indicates that teachers improved their…

  14. Master Curriculum Guide in Economics. A Framework for Teaching the Basic Concepts. Second Edition.

    ERIC Educational Resources Information Center

    Saunders, Phillip; And Others

    Intended for curriculum developers, this revised Framework presents a set of basic concepts for teaching K-12 economics. The revision reflects the change and development which the field of economics has undergone and includes improvements suggested by users of the first edition. The purpose of teaching economics is to impart a general…

  15. The Effectiveness of Programed Instruction Versus the Lecture-Discussion Method of Teaching Basic Metallurgical Concepts.

    ERIC Educational Resources Information Center

    Bockman, David Carl

    The purpose of this study was to compare the conventional lecture-discussion method and an illustrated programed textbook method when teaching a unit of instruction on the basic concepts of metallurgy. The control group used a portion of a conventional textbook accompanied by lecture, chalkboard illustration, and class discussion. The experimental…

  16. Spatial Thinking Concepts in Early Grade-Level Geography Standards

    ERIC Educational Resources Information Center

    Anthamatten, Peter

    2010-01-01

    Research in the cognition and learning sciences has demonstrated that the human brain contains basic structures whose functions are to perform a variety of specific spatial reasoning tasks and that children are capable of learning basic spatial concepts at an early age. There has been a call from within geography to recognize research on spatial…

  17. Love, Power, and Conflict: A Systems Model of Interparty Negotiation.

    ERIC Educational Resources Information Center

    Slawski, Carl

    Some basic hypotheses and corresponding definitions of concepts are presented in an effort to succinctly state the relationship between three of the most basic concepts of social science, namely love, power and conflict. This novel theory is an example of limited reduction. However, it is cast so as to be applicable to both micro and macro levels…

  18. After Almost Half-Century Landing on the Moon and Still Countering Basic Astronomy Conceptions

    ERIC Educational Resources Information Center

    Türkmen, Hakan

    2015-01-01

    The purpose of study is to investigate the fifth graders' understandings of the basic astronomy concept and, if they have, to define their misconceptions and then to determine what reason/s behind them. For this purpose, two hundred seventy fifth grade students from 6 different schools participated. Randomly selected 45 students performing under…

  19. The Etymology of Basic Concepts in the Experimental Analysis of Behavior

    ERIC Educational Resources Information Center

    Dinsmoor, James A.

    2004-01-01

    The origins of many of the basic concepts used in the experimental analysis of behavior can be traced to Pavlov's (1927/1960) discussion of unconditional and conditional reflexes in the dog, but often with substantial changes in meaning (e.g., stimulus, response, and reinforcement). Other terms were added by Skinner (1938/1991) to describe his…

  20. Effects of Geographic Information System on the Learning of Environmental Education Concepts in Basic Computer-Mediated Classrooms in Nigeria

    ERIC Educational Resources Information Center

    Adeleke, Ayobami Gideon

    2017-01-01

    This research paper specifically examined the impact of Geographic Information System (GIS) integration in a learning method and on the performance and retention of Environmental Education (EE) concepts in basic social studies. Non-equivalent experimental research design was employed. 126 pupils in four intact, computer-mediated classrooms were…

  1. Virtual laboratory learning media development to improve science literacy skills of mechanical engineering students on basic physics concept of material measurement

    NASA Astrophysics Data System (ADS)

    Jannati, E. D.; Setiawan, A.; Siahaan, P.; Rochman, C.

    2018-05-01

    This study aims to determine the description of virtual laboratory learning media development to improve science literacy skills of Mechanical Engineering students on the concept of basic Physics. Quasi experimental method was employed in this research. The participants of this research were first semester students of mechanical engineering in Majalengka University. The research instrument was readability test of instructional media. The results of virtual laboratory learning media readability test show that the average score is 78.5%. It indicates that virtual laboratory learning media development are feasible to be used in improving science literacy skill of Mechanical Engineering students in Majalengka University, specifically on basic Physics concepts of material measurement.

  2. Standardizing electrofishing power for boat electrofishing: chapter 14

    USGS Publications Warehouse

    Miranda, L.E. (Steve); Bonar, Scott A.; Hubert, Wayne A.; Willis, David W.

    2009-01-01

    Standardizing boat electrofishing entails achieving an accepted level of collection consistency by managing various brand factors, including (1) the temporal and spatial distribution of sampling effort, (2) boat operation, (3) equipment configuration, (4) characteristics of the waveform and energized field, and (5) power transferred to fish. This chapter focuses exclusively on factor 5:L factors 1-4 have been addressed in earlier chapters. Additionally, while the concepts covered in this chapter address boat electrofishing in general, the power settings discussed were developed from tests with primarily warmwater fish communities. Others (see Chapter 9) recommend lower power settings for communities consisting of primarily coldwater fishes. For reviews of basic concepts of electricity, electrofishing theory and systems, fish behavior relative to diverse waveforms, and injury matter, the reader is referred to Novotny (1990), Reynold (1996), and Snyder (2003).

  3. Introduction to a special issue on concept mapping.

    PubMed

    Trochim, William M; McLinden, Daniel

    2017-02-01

    Concept mapping was developed in the 1980s as a unique integration of qualitative (group process, brainstorming, unstructured sorting, interpretation) and quantitative (multidimensional scaling, hierarchical cluster analysis) methods designed to enable a group of people to articulate and depict graphically a coherent conceptual framework or model of any topic or issue of interest. This introduction provides the basic definition and description of the methodology for the newcomer and describes the steps typically followed in its most standard canonical form (preparation, generation, structuring, representation, interpretation and utilization). It also introduces this special issue which reviews the history of the methodology, describes its use in a variety of contexts, shows the latest ways it can be integrated with other methodologies, considers methodological advances and developments, and sketches a vision of the future of the method's evolution. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Knowledge management through the e-learning approach - a case study of online engineering courses

    NASA Astrophysics Data System (ADS)

    Aichouni, Mohamed; Benchicou, Soraya; Nehari, Dris

    2013-06-01

    Though it is universally accepted that the face-to-face approach is the best way for education and training, however, with the advent of the information and communication technologies (mainly the World Wide Web) it became possible to enhance further the methods we are using to teach our students and to share the teaching material within a broaden engineering, technical and business communities. This paper is dedicated to making a review of the basic concepts of knowledge management and e-learning and to show how these two modern concepts can be integrated into engineering education to produce knowledge, disseminate it and share it within virtual interest groups and networks of engineering students, academic teachers and industrial engineers and technicians and business managers. A practical case study will be presented and discussed.

  5. A model for production, perception, and acquisition of actions in face-to-face communication.

    PubMed

    Kröger, Bernd J; Kopp, Stefan; Lowit, Anja

    2010-08-01

    The concept of action as basic motor control unit for goal-directed movement behavior has been used primarily for private or non-communicative actions like walking, reaching, or grasping. In this paper, literature is reviewed indicating that this concept can also be used in all domains of face-to-face communication like speech, co-verbal facial expression, and co-verbal gesturing. Three domain-specific types of actions, i.e. speech actions, facial actions, and hand-arm actions, are defined in this paper and a model is proposed that elucidates the underlying biological mechanisms of action production, action perception, and action acquisition in all domains of face-to-face communication. This model can be used as theoretical framework for empirical analysis or simulation with embodied conversational agents, and thus for advanced human-computer interaction technologies.

  6. Role of Network Science in the Study of Anesthetic State Transitions.

    PubMed

    Lee, UnCheol; Mashour, George A

    2018-04-23

    The heterogeneity of molecular mechanisms, target neural circuits, and neurophysiologic effects of general anesthetics makes it difficult to develop a reliable and drug-invariant index of general anesthesia. No single brain region or mechanism has been identified as the neural correlate of consciousness, suggesting that consciousness might emerge through complex interactions of spatially and temporally distributed brain functions. The goal of this review article is to introduce the basic concepts of networks and explain why the application of network science to general anesthesia could be a pathway to discover a fundamental mechanism of anesthetic-induced unconsciousness. This article reviews data suggesting that reduced network efficiency, constrained network repertoires, and changes in cortical dynamics create inhospitable conditions for information processing and transfer, which lead to unconsciousness. This review proposes that network science is not just a useful tool but a necessary theoretical framework and method to uncover common principles of anesthetic-induced unconsciousness.

  7. An overview of NASA intermittent combustion engine research

    NASA Technical Reports Server (NTRS)

    Willis, E. A.; Wintucky, W. T.

    1984-01-01

    This paper overviews the current program, whose objective is to establish the generic technology base for advanced aircraft I.C. engines of the early 1990's and beyond. The major emphasis of this paper is on development of the past two years. Past studies and ongoing confirmatory experimental efforts are reviewed, which show unexpectedly high potential when modern aerospace technologies are applied to inherently compact and balanced I.C. engine configurations. Currently, the program is focussed on two engine concepts, the stratified-charge, multi-fuel rotary and the lightweight two-stroke diesel. A review is given of contracted and planned high performance one-rotor and one-cylinder test engine work addressing several levels of technology. Also reviewed are basic supporting efforts, e.g., the development and experimental validation of computerized airflow and combustion process models, being performed in-house at Lewis Research Center and by university grants. Previously announced in STAR as N84-24583

  8. An overview of NASA intermittent combustion engine research

    NASA Technical Reports Server (NTRS)

    Willis, E. A.; Wintucky, W. T.

    1984-01-01

    This paper overviews the current program, whose objective is to establish the generic technology base for advanced aircraft I.C. engines of the early 1990's and beyond. The major emphasis of this paper is on development of the past two years. Past studies and ongoing confirmatory experimental efforts are reviewed, which show unexpectly high potential when modern aerospace technologies are applied to inherently compact and balanced I.C. engine configurations. Currently, the program is focussed on two engine concepts the stratified-charge, multi-fuel rotary, and the lightweight two-stroke diesel. A review is given of contracted and planned high performance one-rotor and one-cylinder test engine work addressing several levels of technology. Also reviewed are basic supporting efforts, e.g., the development and experimental validation of computerized airflow and combustion process models, being performed in-house at Lewis Research Center and by university grants.

  9. The mechanical behavior of nanoscale metallic multilayers: A survey

    NASA Astrophysics Data System (ADS)

    Zhou, Q.; Xie, J. Y.; Wang, F.; Huang, P.; Xu, K. W.; Lu, T. J.

    2015-06-01

    The mechanical behavior of nanoscale metallic multilayers (NMMs) has attracted much attention from both scientific and practical views. Compared with their monolithic counterparts, the large number of interfaces existing in the NMMs dictates the unique behavior of this special class of structural composite materials. While there have been a number of reviews on the mechanical mechanism of microlaminates, the rapid development of nanotechnology brought a pressing need for an overview focusing exclusively on a property-based definition of the NMMs, especially their size-dependent microstructure and mechanical performance. This article attempts to provide a comprehensive and up-to-date review on the microstructure, mechanical property and plastic deformation physics of NMMs. We hope this review could accomplish two purposes: (1) introducing the basic concepts of scaling and dimensional analysis to scientists and engineers working on NMM systems, and (2) providing a better understanding of interface behavior and the exceptional qualities the interfaces in NMMs display at atomic scale.

  10. Health, vital goals, and central human capabilities.

    PubMed

    Venkatapuram, Sridhar

    2013-06-01

    I argue for a conception of health as a person's ability to achieve or exercise a cluster of basic human activities. These basic activities are in turn specified through free-standing ethical reasoning about what constitutes a minimal conception of a human life with equal human dignity in the modern world. I arrive at this conception of health by closely following and modifying Lennart Nordenfelt's theory of health which presents health as the ability to achieve vital goals. Despite its strengths I transform Nordenfelt's argument in order to overcome three significant drawbacks. Nordenfelt makes vital goals relative to each community or context and significantly reflective of personal preferences. By doing so, Nordenfelt's conception of health faces problems with both socially relative concepts of health and subjectively defined wellbeing. Moreover, Nordenfelt does not ever explicitly specify a set of vital goals. The theory of health advanced here replaces Nordenfelt's (seemingly) empty set of preferences and society-relative vital goals with a human species-wide conception of basic vital goals, or 'central human capabilities and functionings'. These central human capabilities come out of the capabilities approach (CA) now familiar in political philosophy and economics, and particularly reflect the work of Martha Nussbaum. As a result, the health of an individual should be understood as the ability to achieve a basic cluster of beings and doings-or having the overarching capability, a meta-capability, to achieve a set of central or vital inter-related capabilities and functionings. © 2012 John Wiley & Sons Ltd.

  11. HEALTH, VITAL GOALS, AND CENTRAL HUMAN CAPABILITIES

    PubMed Central

    Venkatapuram, Sridhar

    2013-01-01

    I argue for a conception of health as a person's ability to achieve or exercise a cluster of basic human activities. These basic activities are in turn specified through free-standing ethical reasoning about what constitutes a minimal conception of a human life with equal human dignity in the modern world. I arrive at this conception of health by closely following and modifying Lennart Nordenfelt's theory of health which presents health as the ability to achieve vital goals. Despite its strengths I transform Nordenfelt's argument in order to overcome three significant drawbacks. Nordenfelt makes vital goals relative to each community or context and significantly reflective of personal preferences. By doing so, Nordenfelt's conception of health faces problems with both socially relative concepts of health and subjectively defined wellbeing. Moreover, Nordenfelt does not ever explicitly specify a set of vital goals. The theory of health advanced here replaces Nordenfelt's (seemingly) empty set of preferences and society-relative vital goals with a human species-wide conception of basic vital goals, or ‘central human capabilities and functionings’. These central human capabilities come out of the capabilities approach (CA) now familiar in political philosophy and economics, and particularly reflect the work of Martha Nussbaum. As a result, the health of an individual should be understood as the ability to achieve a basic cluster of beings and doings—or having the overarching capability, a meta-capability, to achieve a set of central or vital inter-related capabilities and functionings. PMID:22420910

  12. Radio frequency identification: the big role player in health care management.

    PubMed

    Mehrjerdi, Yahia Zare

    2011-01-01

    This paper seeks to review the fundamental concepts of radio frequency identification (RFID) and to discuss the fact that the road to success for healthcare systems is the thorough management of patients, employees, equipment, medications, and records throughout the industry. Thereafter, it aims to prepare a deep review of the technology, study seven new cases on the topic of healthcare management and deliver a broad applications area thereof. The paper identifies key elements of RFID through the review of healthcare management literature and case studies. For this purpose, seven cases from the healthcare industry are reviewed to demonstrate the extent of the applications of RFID in this area. To make healthcare management systems functional and successfully operational, RFID solutions can be used to reduce operating costs through management of patients, employees, equipment, medications, and records to improve tracking and tracing, and preventing the lost of resources under any circumstances. This paper delivers a review of RFID on the healthcare industry. For this reason, the basic and key point on RFID technology is discussed and seven cases from the literature are reviewed.

  13. The Ratu River Expedition - A Case Study in Successful Outreach Using Film and Social Media

    NASA Astrophysics Data System (ADS)

    Kerlow, Isaac

    2016-04-01

    The Ratu River Expedition is a 25-minute film about earthquakes in Nepal made for a general audience and for a Nepalese audience in particular. The movie explains basic facts about seismic activity in the Himalaya region and also basic preparedness concepts. It showcases the scientific research of the Structural Geology group at the Earth Observatory of Singapore in collaboration with the Department of Mines and Geology, Nepal. A social media campaign was developed to bring the movie to a large Nepalese audience, and the Nepali-subtitled version of the movie yielded over 79,000 post Likes in a Facebook outreach campaign. This presentation reviews the development, production, and distribution of this highly successful natural hazards documentary with scientific depth but designed for a mainstream audience. The full movie is being shown at EGU's Geo-Cinema 2016. http://raturiver.com/

  14. The Origins and Organization of Vertebrate Pavlovian Conditioning

    PubMed Central

    Fanselow, Michael S.; Wassum, Kate M.

    2016-01-01

    Pavlovian conditioning is the process by which we learn relationships between stimuli and thus constitutes a basic building block for how the brain constructs representations of the world. We first review the major concepts of Pavlovian conditioning and point out many of the pervasive misunderstandings about just what conditioning is. This brings us to a modern redefinition of conditioning as the process whereby experience with a conditional relationship between stimuli bestows these stimuli with the ability to promote adaptive behavior patterns that did not occur before the experience. Working from this framework, we provide an in-depth analysis of two examples, fear conditioning and food-based appetitive conditioning, which include a description of the only partially overlapping neural circuitry of each. We also describe how these circuits promote the basic characteristics that define Pavlovian conditioning, such as error-correction-driven regulation of learning. PMID:26552417

  15. Teaching Two Basic Nanotechnology Concepts in Secondary School by Using a Variety of Teaching Methods

    ERIC Educational Resources Information Center

    Blonder, Ron; Sakhnini, Sohair

    2012-01-01

    A nanotechnology module was developed for ninth grade students in the context of teaching chemistry. Two basic concepts in nanotechnology were chosen: (1) size and scale and (2) surface-area-to-volume ratio (SA/V). A wide spectrum of instructional methods (e.g., game-based learning, learning with multimedia, learning with models, project based…

  16. Representational Competence in Chemistry: A Comparison between Students with Different Levels of Understanding of Basic Chemical Concepts and Chemical Representations

    ERIC Educational Resources Information Center

    Sim, Joong Hiong; Daniel, Esther Gnanamalar Sarojini

    2014-01-01

    Representational competence is defined as "skills in interpreting and using representations". This study attempted to compare students' of high, medium, and low levels of understanding of (1) basic chemical concepts, and (2) chemical representations, in their representational competence. A total of 411 Form 4 science students (mean age =…

  17. Mapping the Relationships among Basic Facts, Concepts and Application, and Common Core Curriculum-Based Mathematics Measures

    ERIC Educational Resources Information Center

    Codding, Robin S.; Mercer, Sterett; Connell, James; Fiorello, Catherine; Kleinert, Whitney

    2016-01-01

    There is a paucity of evidence supporting the use of curriculum-based mathematics measures (M-CBMs) at the middle school level, which makes data-based decisions challenging for school professionals. The purpose of this study was to examine the relationships among three existing M-CBM indices: (a) basic facts, (b) concepts/application, and (c)…

  18. Inservice Elementary and Middle School Teachers' Conceptions of Photosynthesis and Respiration

    ERIC Educational Resources Information Center

    Krall, Rebecca McNall; Lott, Kimberly H.; Wymer, Carol L.

    2009-01-01

    The purpose of this descriptive study was to investigate inservice elementary and middle school teachers' conceptions of photosynthesis and respiration, basic concepts they are expected to teach. A forced-choice instrument assessing selected standards-based life science concepts with non-scientific conceptions embedded in distracter options was…

  19. Architecture is Elementary: Visual Thinking through Architectural Concepts.

    ERIC Educational Resources Information Center

    Winters, Nathan B.

    This book presents very basic but important concepts about architecture and outlines some of the most important concepts used by great architects. These concepts are taught at levels of perceptual maturity applicable to adults and children alike and progress from levels one through seven as the concepts become progressively intertwined. The…

  20. Nurses' policy influence: A concept analysis.

    PubMed

    Arabi, Akram; Rafii, Forough; Cheraghi, Mohammad Ali; Ghiyasvandian, Shahrzad

    2014-05-01

    Nurses' influence on health policy protects the quality of care by access to required recourses and opportunities. This is a new and important concept for nursing; however, research studies on policy influence of nurses in health care sector are lacking a basic conceptual understanding of what this concept represents. The aim of this paper is to clarify the concept of nurses' policy influence and to propose the definition of this concept, considering the context of Iran. The eight stages of Walker and Avant approach was used to guide this concept analysis. Various databases and internet engines were searched to find all related information about the concept. Textbooks were also searched manually. English language literature reports published between 1990 and 2012 were reviewed. Based on the analysis undertaken, nurses' policy influence is nurses' ability in influencing decisions and affairs related to health through political knowledge, effective communication, and collaboration with other members of the health team, which results in the improvement of nurses' job environment and increases patient outcomes. This is a dynamic process situated on a spectrum and is accompanied with nurses' knowledge, competency, power, and advocacy, and also their ability to change. Nurses have individual views on health care issues and influence health care policies in different ways. With a common understanding of nurses' policy influence as a concept, nurses will recognize the importance of policy making in the health sector and their influence on this process and also on patients' outcomes.

  1. Protein-Protein Interface Predictions by Data-Driven Methods: A Review

    PubMed Central

    Xue, Li C; Dobbs, Drena; Bonvin, Alexandre M.J.J.; Honavar, Vasant

    2015-01-01

    Reliably pinpointing which specific amino acid residues form the interface(s) between a protein and its binding partner(s) is critical for understanding the structural and physicochemical determinants of protein recognition and binding affinity, and has wide applications in modeling and validating protein interactions predicted by high-throughput methods, in engineering proteins, and in prioritizing drug targets. Here, we review the basic concepts, principles and recent advances in computational approaches to the analysis and prediction of protein-protein interfaces. We point out caveats for objectively evaluating interface predictors, and discuss various applications of data-driven interface predictors for improving energy model-driven protein-protein docking. Finally, we stress the importance of exploiting binding partner information in reliably predicting interfaces and highlight recent advances in this emerging direction. PMID:26460190

  2. Fusion Imaging for Procedural Guidance.

    PubMed

    Wiley, Brandon M; Eleid, Mackram F; Thaden, Jeremy J

    2018-05-01

    The field of percutaneous structural heart interventions has grown tremendously in recent years. This growth has fueled the development of new imaging protocols and technologies in parallel to help facilitate these minimally-invasive procedures. Fusion imaging is an exciting new technology that combines the strength of 2 imaging modalities and has the potential to improve procedural planning and the safety of many commonly performed transcatheter procedures. In this review we discuss the basic concepts of fusion imaging along with the relative strengths and weaknesses of static vs dynamic fusion imaging modalities. This review will focus primarily on echocardiographic-fluoroscopic fusion imaging and its application in commonly performed transcatheter structural heart procedures. Copyright © 2017 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

  3. Review of guidelines and literature for handling missing data in longitudinal clinical trials with a case study.

    PubMed

    Liu, M; Wei, L; Zhang, J

    2006-01-01

    Missing data in clinical trials are inevitable. We highlight the ICH guidelines and CPMP points to consider on missing data. Specifically, we outline how we should consider missing data issues when designing, planning and conducting studies to minimize missing data impact. We also go beyond the coverage of the above two documents, provide a more detailed review of the basic concepts of missing data and frequently used terminologies, and examples of the typical missing data mechanism, and discuss technical details and literature for several frequently used statistical methods and associated software. Finally, we provide a case study where the principles outlined in this paper are applied to one clinical program at protocol design, data analysis plan and other stages of a clinical trial.

  4. Indocyanine green kinetics to assess liver function: Ready for a clinical dynamic assessment in major liver surgery?

    PubMed Central

    De Gasperi, Andrea; Mazza, Ernestina; Prosperi, Manlio

    2016-01-01

    Indocyanine green (ICG) kinetics (PDR/R15) used to quantitatively assess hepatic function in the perioperative period of major resective surgery and liver transplantation have been the object of an extensive, updated and critical review. New, non invasive bedside monitors (pulse dye densitometry technology) make this opportunity widely available in clinical practice. After having reviewed basic concepts of hepatic clearance, we analysed the most common indications ICG kinetic parameters have nowadays in clinical practice, focusing in particular on the diagnostic and prognostic role of PDR and R15 in the perioperative period of major liver surgery and liver transplantation. As recently pointed out, even if of extreme interest, ICG clearance parameters have still some limitations, to be considered when using these tests. PMID:26981173

  5. Cardiac Point-of-Care Ultrasound: State of the Art in Medical School Education.

    PubMed

    Johri, Amer M; Durbin, Joshua; Newbigging, Joseph; Tanzola, Robert; Chow, Ryan; De, Sabe; Tam, James

    2018-03-14

    The development of small, user friendly, handheld ultrasound devices has stimulated the growth of cardiac point-of-care ultrasound (POCUS) for the purpose of rapid, bedside cardiac assessment. Medical schools have begun integrating cardiac POCUS into their curricula. In this review the authors summarize the variable approaches taken by several medical training programs with respect to duration of POCUS training, prerequisite knowledge, and methods of delivering these skills (including e-learning, hands-on training, and simulation). The authors also address issues related to the need for competency evaluation and the limitations of the technology itself. The studies reviewed suggest that undergraduate education is a viable point at which to introduce basic POCUS concepts. Copyright © 2018 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.

  6. Production process stability - core assumption of INDUSTRY 4.0 concept

    NASA Astrophysics Data System (ADS)

    Chromjakova, F.; Bobak, R.; Hrusecka, D.

    2017-06-01

    Today’s industrial enterprises are confronted by implementation of INDUSTRY 4.0 concept with basic problem - stabilised manufacturing and supporting processes. Through this phenomenon of stabilisation, they will achieve positive digital management of both processes and continuously throughput. There is required structural stability of horizontal (business) and vertical (digitized) manufacturing processes, supported through digitalised technologies of INDUSTRY 4.0 concept. Results presented in this paper based on the research results and survey realised in more industrial companies. Following will described basic model for structural process stabilisation in manufacturing environment.

  7. Learning basic programming using CLIS through gamification

    NASA Astrophysics Data System (ADS)

    Prabawa, H. W.; Sutarno, H.; Kusnendar, J.; Rahmah, F.

    2018-05-01

    The difficulty of understanding programming concept is a major problem in basic programming lessons. Based on the results of preliminary studies, 60% of students reveal the monotonous of learning process caused by the limited number of media. Children Learning in Science (CLIS) method was chosen as solution because CLIS has facilitated students’ initial knowledge to be optimized into conceptual knowledge. Technological involvement in CLIS (gamification) helped students to understand basic programming concept. This research developed a media using CLIS method with gamification elements to increase the excitement of learning process. This research declared that multimedia is considered good by students, especially regarding the mechanical aspects of multimedia, multimedia elements and aspects of multimedia information structure. Multimedia gamification learning with the CLIS model showed increased number of students’ concept understanding.

  8. Making finance work for you.

    PubMed

    Marchwinski, Jay

    2002-01-01

    Every organization has a process for reviewing requests against their own guidelines, which are not always well defined. Normally, all requests must be able to demonstrate an adequate financial return on any investment of dollars and/or resources. Quality and service improvement benefits sometimes are accepted, but often must be translated into documentable dollars and cents. In this article, the author shows how understanding the basic concepts of revenue and expense is a good first step toward improving your chances of gaining approval. Forming an effective two-way partnership with the staff in your finance department will improve your chances even more.

  9. Hairstyles in the arts of Greek and Roman antiquity.

    PubMed

    Haas, Norbert; Toppe, Francoise; Henz, Beate M

    2005-12-01

    Styling one's hair seems to be an innate desire of humans to emphasize their beauty and power. As reviewed here, hairstyles were influenced by preceding cultures, by religion, by those depicted for gods and emperors on sculptures and coins. In addition, they were determined by aspects of lifestyle such as sports, wealth, and the desire to display inner feelings. The historical changes in fashions can be exemplarily followed by a visitor to an art collection of Graeco-Roman antiquity. The study of hairstyles permits an insight into very basic aspects of the self-conception of individuals and of the respective societies.

  10. The advantages of problem-based curricula.

    PubMed Central

    Dolmans, D.; Schmidt, H.

    1996-01-01

    Problem-based curricula provide a learning environment in which competence is fostered not primarily by teaching to impart knowledge, but through encouraging an inquisitive style of learning. Preliminary discussion in small groups, contextual learning, integration of knowledge and an emphasis on patient problems, have several cognitive effects on student learning. These effects are increased retention of knowledge, enhancement of integration of basic science concepts into clinical problems, the development of self-directed learning skills, and the enhancement of students' intrinsic interest in the subject matter. In this paper a number of studies will be reviewed that provide empirical evidence for these premises. PMID:8949589

  11. A decade of molecular cell biology: achievements and challenges.

    PubMed

    Akhtar, Asifa; Fuchs, Elaine; Mitchison, Tim; Shaw, Reuben J; St Johnston, Daniel; Strasser, Andreas; Taylor, Susan; Walczak, Claire; Zerial, Marino

    2011-09-23

    Nature Reviews Molecular Cell Biology celebrated its 10-year anniversary during this past year with a series of specially commissioned articles. To complement this, here we have asked researchers from across the field for their insights into how molecular cell biology research has evolved during this past decade, the key concepts that have emerged and the most promising interfaces that have developed. Their comments highlight the broad impact that particular advances have had, some of the basic understanding that we still require, and the collaborative approaches that will be essential for driving the field forward.

  12. Interactive Chemistry Journey (by Steven D. Gammon, Lynn Hunsberger, Sharon Hutchison)

    NASA Astrophysics Data System (ADS)

    McCool, Debra J.

    1998-05-01

    Prentice Hall: Upper Saddle River, NJ, 1997. CD-ROM (Hybrid, MAC and WIN). ISBN 013 548116-3. 26.25 purchased separately; 10.00 when purchased with Prentice Hall Textbook. Interactive Chemistry Journey is a single CD-ROM packed with excellent chemistry content. Every topic that would be covered in high school chemistry and first-year college chemistry is well represented: basic skills, energy and matter, atomic structure, molecular structure, gases, kinetics, and equilibrium. Each content unit has interactive lessons and problems, including MCAT review questions. Several units have simulations that the student can manipulate to better understand the concepts.

  13. Multimodal Imaging of Human Brain Activity: Rational, Biophysical Aspects and Modes of Integration

    PubMed Central

    Blinowska, Katarzyna; Müller-Putz, Gernot; Kaiser, Vera; Astolfi, Laura; Vanderperren, Katrien; Van Huffel, Sabine; Lemieux, Louis

    2009-01-01

    Until relatively recently the vast majority of imaging and electrophysiological studies of human brain activity have relied on single-modality measurements usually correlated with readily observable or experimentally modified behavioural or brain state patterns. Multi-modal imaging is the concept of bringing together observations or measurements from different instruments. We discuss the aims of multi-modal imaging and the ways in which it can be accomplished using representative applications. Given the importance of haemodynamic and electrophysiological signals in current multi-modal imaging applications, we also review some of the basic physiology relevant to understanding their relationship. PMID:19547657

  14. Microdialysis as a way to measure antibiotics concentration in tissues.

    PubMed

    Marchand, Sandrine; Chauzy, Alexia; Dahyot-Fizelier, Claire; Couet, William

    2016-09-01

    As for all other drugs, antibiotics must reach their pharmacodynamic target in order to exert their effect, but because infection may occur in various tissues the distribution of antibiotics has always been of particular concern. In this article, we will first critically review the various methodologies available to study antibiotics tissue distribution, including microdialysis, secondly we will show how basic pharmacokinetic concepts may help to predict or interpret antibiotics tissue distribution and third we will address the question of linking antibiotics tissue distribution with their antimicrobial effect, using modern pharmacokinetic-pharmacodynamic methods. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Hydrodynamic theory of active matter

    NASA Astrophysics Data System (ADS)

    Jülicher, Frank; Grill, Stephan W.; Salbreux, Guillaume

    2018-07-01

    We review the general hydrodynamic theory of active soft materials that is motivated in particular by biological matter. We present basic concepts of irreversible thermodynamics of spatially extended multicomponent active systems. Starting from the rate of entropy production, we identify conjugate thermodynamic fluxes and forces and present generic constitutive equations of polar active fluids and active gels. We also discuss angular momentum conservation which plays a role in the the physics of active chiral gels. The irreversible thermodynamics of active gels provides a general framework to discuss the physics that underlies a wide variety of biological processes in cells and in multicellular tissues.

  16. A decade of molecular cell biology: achievements and challenges

    PubMed Central

    Akhtar, Asifa; Fuchs, Elaine; Mitchison, Tim; Shaw, Reuben J.; St Johnston, Daniel; Strasser, Andreas; Taylor, Susan; Walczak, Claire; Zerial, Marino

    2012-01-01

    Nature Reviews Molecular Cell Biology celebrated its 10-year anniversary during this past year with a series of specially commissioned articles. To complement this, here we have asked researchers from across the field for their insights into how molecular cell biology research has evolved during this past decade, the key concepts that have emerged and the most promising interfaces that have developed. Their comments highlight the broad impact that particular advances have had, some of the basic understanding that we still require, and the collaborative approaches that will be essential for driving the field forward. PMID:21941276

  17. AKAPs: The Architectural Underpinnings of Local cAMP signaling

    PubMed Central

    Kritzer, Michael D.; Li, Jinliang; Dodge-Kafka, Kimberly; Kapiloff, Michael S.

    2011-01-01

    The cAMP-dependent protein kinase A (PKA) is targeted to specific compartments in the cardiac myocyte by A-kinase anchoring proteins (AKAPs), a diverse set of scaffold proteins that have been implicated in the regulation of excitation-contraction coupling and cardiac remodeling. AKAPs bind not only PKA, but also a large variety of structural and signaling molecules. In this review, we discuss the basic concepts underlying compartmentation of cAMP and PKA signaling, as well as a few of the individual AKAPs that have been shown to be functionally relevant in the heart. PMID:21600214

  18. Robotic space construction

    NASA Technical Reports Server (NTRS)

    Mixon, Randolph W.; Hankins, Walter W., III; Wise, Marion A.

    1988-01-01

    Research at Langley AFB concerning automated space assembly is reviewed, including a Space Shuttle experiment to test astronaut ability to assemble a repetitive truss structure, testing the use of teleoperated manipulators to construct the Assembly Concept for Construction of Erectable Space Structures I truss, and assessment of the basic characteristics of manipulator assembly operations. Other research topics include the simultaneous coordinated control of dual-arm manipulators and the automated assembly of candidate Space Station trusses. Consideration is given to the construction of an Automated Space Assembly Laboratory to study and develop the algorithms, procedures, special purpose hardware, and processes needed for automated truss assembly.

  19. Quantifying iron content in magnetic resonance imaging.

    PubMed

    Ghassaban, Kiarash; Liu, Saifeng; Jiang, Caihong; Haacke, E Mark

    2018-04-25

    Measuring iron content has practical clinical indications in the study of diseases such as Parkinson's disease, Huntington's disease, ferritinopathies and multiple sclerosis as well as in the quantification of iron content in microbleeds and oxygen saturation in veins. In this work, we review the basic concepts behind imaging iron using T2, T2*, T2', phase and quantitative susceptibility mapping in the human brain, liver and heart, followed by the applications of in vivo iron quantification in neurodegenerative diseases, iron tagged cells and ultra-small superparamagnetic iron oxide (USPIO) nanoparticles. Copyright © 2018 Elsevier Inc. All rights reserved.

  20. A brief simulation intervention increasing basic science and clinical knowledge.

    PubMed

    Sheakley, Maria L; Gilbert, Gregory E; Leighton, Kim; Hall, Maureen; Callender, Diana; Pederson, David

    2016-01-01

    The United States Medical Licensing Examination (USMLE) is increasing clinical content on the Step 1 exam; thus, inclusion of clinical applications within the basic science curriculum is crucial. Including simulation activities during basic science years bridges the knowledge gap between basic science content and clinical application. To evaluate the effects of a one-off, 1-hour cardiovascular simulation intervention on a summative assessment after adjusting for relevant demographic and academic predictors. This study was a non-randomized study using historical controls to evaluate curricular change. The control group received lecture (n l=515) and the intervention group received lecture plus a simulation exercise (n l+s=1,066). Assessment included summative exam questions (n=4) that were scored as pass/fail (≥75%). USMLE-style assessment questions were identical for both cohorts. Descriptive statistics for variables are presented and odds of passage calculated using logistic regression. Undergraduate grade point ratio, MCAT-BS, MCAT-PS, age, attendance at an academic review program, and gender were significant predictors of summative exam passage. Students receiving the intervention were significantly more likely to pass the summative exam than students receiving lecture only (P=0.0003). Simulation plus lecture increases short-term understanding as tested by a written exam. A longitudinal study is needed to assess the effect of a brief simulation intervention on long-term retention of clinical concepts in a basic science curriculum.

  1. A brief simulation intervention increasing basic science and clinical knowledge.

    PubMed

    Sheakley, Maria L; Gilbert, Gregory E; Leighton, Kim; Hall, Maureen; Callender, Diana; Pederson, David

    2016-01-01

    Background The United States Medical Licensing Examination (USMLE) is increasing clinical content on the Step 1 exam; thus, inclusion of clinical applications within the basic science curriculum is crucial. Including simulation activities during basic science years bridges the knowledge gap between basic science content and clinical application. Purpose To evaluate the effects of a one-off, 1-hour cardiovascular simulation intervention on a summative assessment after adjusting for relevant demographic and academic predictors. Methods This study was a non-randomized study using historical controls to evaluate curricular change. The control group received lecture (n l =515) and the intervention group received lecture plus a simulation exercise (n l+s =1,066). Assessment included summative exam questions (n=4) that were scored as pass/fail (≥75%). USMLE-style assessment questions were identical for both cohorts. Descriptive statistics for variables are presented and odds of passage calculated using logistic regression. Results Undergraduate grade point ratio, MCAT-BS, MCAT-PS, age, attendance at an academic review program, and gender were significant predictors of summative exam passage. Students receiving the intervention were significantly more likely to pass the summative exam than students receiving lecture only (P=0.0003). Discussion Simulation plus lecture increases short-term understanding as tested by a written exam. A longitudinal study is needed to assess the effect of a brief simulation intervention on long-term retention of clinical concepts in a basic science curriculum.

  2. An Analysis of Teachers' Concept Confusion Concerning Electric and Magnetic Fields

    ERIC Educational Resources Information Center

    Hekkenberg, Ans; Lemmer, Miriam; Dekkers, Peter

    2015-01-01

    In an exploratory study, 36 South African physical science teachers' understanding of basic concepts concerning electric and magnetic fields was studied from a perspective of possible concept confusion. Concept confusion is said to occur when features of one concept are incorrectly attributed to a different concept, in the case of this study to…

  3. Electronegative Gas Thruster - Direct Thrust Measurement Project

    NASA Technical Reports Server (NTRS)

    Dankanich, John (Principal Investigator); Aanesland, Ane; Polzin, Kurt; Walker, Mitchell

    2015-01-01

    This effort is an international collaboration and academic partnership to mature an innovative electric propulsion (EP) thruster concept to TRL 3 through direct thrust measurement. The initial target application is for Small Satellites, but can be extended to higher power. The Plasma propulsion with Electronegative GASES (PEGASES) concept simplifies ion thruster operation, eliminates a neutralizer requirement and should yield longer life capabilities and lower cost implementation over conventional gridded ion engines. The basic proof-of concept has been demonstrated and matured to TRL 2 over the past several years by researchers at the Laboratoire de Physique des Plasma in France. Due to the low maturity of the innovation, there are currently no domestic investments in electronegative gas thrusters anywhere within NASA, industry or academia. The end product of this Center Innovation Fund (CIF) project will be a validation of the proof-of-concept, maturation to TRL 3 and technology assessment report to summarize the potential for the PEGASES concept to supplant the incumbent technology. Information exchange with the foreign national will be one-way with the exception of the test results. Those test results will first go through a standard public release ITAR/export control review, and the results will be presented in a public technical forum, and the results will be presented in a public technical forum.

  4. [Education and the rights of man. Press review: Mauritania].

    PubMed

    1999-12-01

    We are now poised at the brink of a revolution in education, based upon a broadened and renewed concept of what defines education and apprenticeship. We have come to this point because of our realization during the 1990s that human rights are a key element of human development. Humanity recognizes today that human rights are indivisible and that the realization of one right leads to the reinforcement and promotion of another. Man has the right to education, freedom of speech and thought, and protection from torture. This is a very important concept for the developing world, where approximately 130 million children grow up without being properly educated. Governments are obligated to take the necessary measures to ensure that children receive a quality, basic education. Countries deficient in this domain often argue that they do not have enough resources to educate all of their populations, despite 30 years of evidence demonstrating how much developing countries can achieve in education with only limited means. Countries least advanced in achieving education for all have often inequitably invested more funds into higher education than into basic education. They have also failed to contain costs as scholastic coverage expanded. Efforts must be made to minimize the financial cost to parents of educating their children.

  5. Fractals in the neurosciences, Part II: clinical applications and future perspectives.

    PubMed

    Di Ieva, Antonio; Esteban, Francisco J; Grizzi, Fabio; Klonowski, Wlodzimierz; Martín-Landrove, Miguel

    2015-02-01

    It has been ascertained that the human brain is a complex system studied at multiple scales, from neurons and microcircuits to macronetworks. The brain is characterized by a hierarchical organization that gives rise to its highly topological and functional complexity. Over the last decades, fractal geometry has been shown as a universal tool for the analysis and quantification of the geometric complexity of natural objects, including the brain. The fractal dimension has been identified as a quantitative parameter for the evaluation of the roughness of neural structures, the estimation of time series, and the description of patterns, thus able to discriminate different states of the brain in its entire physiopathological spectrum. Fractal-based computational analyses have been applied to the neurosciences, particularly in the field of clinical neurosciences including neuroimaging and neuroradiology, neurology and neurosurgery, psychiatry and psychology, and neuro-oncology and neuropathology. After a review of the basic concepts of fractal analysis and its main applications to the basic neurosciences in part I of this series, here, we review the main applications of fractals to the clinical neurosciences for a holistic approach towards a fractal geometry model of the brain. © The Author(s) 2013.

  6. Review of cross-cultural issues related to quality of life after spinal cord injury.

    PubMed

    Tate, Denise; Forchheimer, Martin

    2014-01-01

    Quality of life (QOL) is a dynamic concept that means different things to different people, both in the general public and within the research community. Because of this, a common definition of QOL has been hard to achieve. This article reviews cross-cultural issues related to QOL research in spinal cord injury (SCI). Many factors influence QOL for persons with SCI, including observable and objective indicators and subjective self-report ones. The World Health Organization's International Classification of Function, Disability and Health is used in this article as a framework to better understand how these factors may influence QOL. A number of important steps are summarized with respect to measurement issues in QOL. A comparison between data from 2 countries (United States and Brazil) using the International SCI QOL Basic Data Set shows similarities in scores and good reliability in the Brazilian sample. Substantial, significant correlations were observed among the SCI QOL Basic Data Set items and the WHOQOL-BREF within the US sample. The article ends with a set of recommendations for the development of cross-cultural measures of QOL for use in the SCI population.

  7. "Anatomy and imaging": 10 years of experience with an interdisciplinary teaching project in preclinical medical education - from an elective to a curricular course.

    PubMed

    Schober, A; Pieper, C C; Schmidt, R; Wittkowski, W

    2014-05-01

    Presentation of an interdisciplinary, interactive, tutor-based preclinical teaching project called "Anatomy and Imaging". Experience report, analysis of evaluation results and selective literature review. From 2001 to 2012, 618 students took the basic course (4 periods per week throughout the semester) and 316 took the advanced course (2 periods per week). We reviewed 557 (return rate 90.1 %) and 292 (92.4 %) completed evaluation forms of the basic and the advanced course. Results showed overall high satisfaction with the courses (1.33 and 1.56, respectively, on a 5-point Likert scale). The recognizability of the relevance of the course content for medical training, the promotion of the interest in medicine and the quality of the student tutors were evaluated especially positively. The "Anatomy and Imaging" teaching project is a successful concept for integrating medical imaging into the preclinical stage of medical education. The course was offered as part of the curriculum in 2013 for the first time. "Anatomia in mortuis" and "Anatomia in vivo" are not regarded as rivaling entities in the delivery of knowledge, but as complementary methods. © Georg Thieme Verlag KG Stuttgart · New York.

  8. Improved knowledge gain and retention for third-year medical students during surgical journal club using basic science review: A pilot study.

    PubMed

    Williams, Austin D; Mann, Barry D

    2017-02-01

    As they enter the clinical years, medical students face large adjustments in the acquisition of medical knowledge. We hypothesized that basic science review related to the topic of journal club papers would increase the educational benefit for third-year medical students. Students were randomized either to participation in a review session about basic science related to the journal club paper, or to no review. After one day, and after three months, students were given a 10-question quiz encompassing the basic science and the clinical implications of the paper. Twenty-six of 50 students were randomized to basic science review. These students scored better on both sections of the quiz one day after journal club, but only on basic science questions after three months. Students who participated in basic science review had better knowledge gain and retention. Educational activities building upon foundational knowledge improves learning on clinical rotations. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Development of a prototype two-phase thermal bus system for Space Station

    NASA Technical Reports Server (NTRS)

    Myron, D. L.; Parish, R. C.

    1987-01-01

    This paper describes the basic elements of a pumped two-phase ammonia thermal control system designed for microgravity environments, the development of the concept into a Space Station flight design, and design details of the prototype to be ground-tested in the Johnson Space Center (JSC) Thermal Test Bed. The basic system concept is one of forced-flow heat transport through interface heat exchangers with anhydrous ammonia being pumped by a device expressly designed for two-phase fluid management in reduced gravity. Control of saturation conditions, and thus system interface temperatures, is accomplished with a single central pressure regulating valve. Flow control and liquid inventory are controlled by passive, nonelectromechanical devices. Use of these simple control elements results in minimal computer controls and high system reliability. Building on the basic system concept, a brief overview of a potential Space Station flight design is given. Primary verification of the system concept will involve testing at JSC of a 25-kW ground test article currently in fabrication.

  10. Innovations in human genetics education. Incorporation of genetics into a problem-based medical school curriculum.

    PubMed Central

    Swinford, A E; McKeag, D B

    1990-01-01

    There has been recent interest in the development of problem-based human genetics curricula in U.S. medical schools. The College of Human Medicine at Michigan State University has had a problem-based curriculum since 1974. The vertical integration of genetics within the problem-based curriculum, called "Track II," has recently been revised. On first inspection, the curriculum appeared to lack a significant genetics component; however, on further analysis it was found that many genetics concepts were covered in the biochemistry, microbiology, pathology, and clinical science components. Both basic science concepts and clinical applications of genetics are covered in the curriculum by providing appropriate references for basic concepts and including inherited conditions within the differential diagnosis in the cases studied. Evaluations consist of a multiple-choice content exam and a modified essay exam based on a clinical case, allowing evaluation of both basic concepts and problem-solving ability. This curriculum prepares students to use genetics in a clinical context in their future careers. PMID:2220816

  11. Survey of Basic Education in Eastern Africa. UNESCO/UNICEF Co-Operation Programme.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Nairobi (Kenya). Regional Office of Science and Technology for Africa.

    A survey of basic education in 13 Eastern African countries (Madagascar, Burundi, Comores, Ethiopia, Mauritius, Botswana, Kenya, Lesotho, Swaziland, Tanzania, Zambia, Malawi, and Somalia) covers basic education programs and UNICEF's supporting role. Basic education is seen as a concept evolved in the region, involving formal school systems and…

  12. Education and Criminal Justice: The Educational Approach to Prison Administration. The United Nations Standard Minimum Rules for the Treatment of Prisoners.

    ERIC Educational Resources Information Center

    Morin, Lucien; Cosman, J. W.

    The United Nations Standard Minimum Rules for the Treatment of Prisoners do not express the basic principle that would support a serious educational approach to prison administration. The crucial missing rationale is the concept of the inherent dignity of the individual human prisoner. This concept has certain basic educational implications,…

  13. Teaching Basic Programming Concepts to Young Primary School Students Using Tablets: Results of a Pilot Project

    ERIC Educational Resources Information Center

    Fokides, Emmanuel

    2018-01-01

    The study presents the results of a project in which tablets and a ready-made application were used for teaching basic programming concepts to young primary school students (ages 7-9). A total of 135 students participated in the study, attending primary schools in Athens, Greece, divided into three groups. The first was taught conventionally. The…

  14. All about Flight. Physical Science for Children[TM]. Schlessinger Science Library. [Videotape].

    ERIC Educational Resources Information Center

    2000

    Up, up and away! A hot air balloon, an airplane and even the space shuttle all defy the force of gravity, but they all do it in different ways. Children will learn about the basic concepts that make flight possible. With clear demonstrations and a hands-on project, students will be able to understand more easily the basic concepts behind various…

  15. Development and Validation of the Life Sciences Assessment: A Measure of Preschool Children's Conceptions of Basic Life Sciences

    ERIC Educational Resources Information Center

    Maherally, Uzma Nooreen

    2014-01-01

    The purpose of this study was to develop and validate a science assessment tool termed the Life Sciences Assessment (LSA) in order to assess preschool children's conceptions of basic life sciences. The hypothesis was that the four sub-constructs, each of which can be measured through a series of questions on the LSA, will make a significant…

  16. High-School Students' Conceptual Difficulties and Attempts at Conceptual Change: The Case of Basic Quantum Chemical Concepts

    ERIC Educational Resources Information Center

    Tsaparlis, Georgios; Papaphotis, Georgios

    2009-01-01

    This study tested for deep understanding and critical thinking about basic quantum chemical concepts taught at 12th grade (age 17-18). Our aim was to achieve conceptual change in students. A quantitative study was conducted first (n = 125), and following this 23 selected students took part in semi-structured interviews either individually or in…

  17. The Effect of 3D Computer Modeling and Observation-Based Instruction on the Conceptual Change regarding Basic Concepts of Astronomy in Elementary School Students

    ERIC Educational Resources Information Center

    Kucukozer, Huseyin; Korkusuz, M. Emin; Kucukozer, H. Asuman; Yurumezoglu, Kemal

    2009-01-01

    This study has examined the impact of teaching certain basic concepts of astronomy through a predict-observe-explain strategy, which includes three-dimensional (3D) computer modeling and observations on conceptual changes seen in sixth-grade elementary school children (aged 11-13; number of students: 131). A pre- and postastronomy instruction…

  18. Flowmeter evaluation for on-orbit operations

    NASA Technical Reports Server (NTRS)

    Baird, R. S.

    1988-01-01

    Various flowmetering concepts were flow tested to characterize the relative capabilities and limitations for on-orbit fluid-transfer operations. Performance results and basic operating principles of each flowmetering concept tested are summarized, and basic considerations required to select the best flowmeter(s) for fluid system application are discussed. Concepts tested were clamp-on ultrasonic, area averaging ultrasonic, offset ultrasonic, coriolis mass, vortex shedding, universal venturi tube, turbine, bearingless turbine, turbine/turbine differential-pressure hybrid, dragbody, and dragbody/turbine hybrid flowmeters. Fluid system flowmeter selection considerations discussed are flowmeter performance, fluid operating conditions, systems operating environments, flowmeter packaging, flowmeter maintenance, and flowmeter technology. No one flowmetering concept tested was shown to be best for all on-orbit fluid systems.

  19. Teamwork: a concept analysis.

    PubMed

    Xyrichis, Andreas; Ream, Emma

    2008-01-01

    This paper is a report of an analysis of the concept of teamwork. Teamwork is seen as an important facilitator in delivering quality healthcare services internationally. However, research studies of teamwork in health care are criticized for lacking a basic conceptual understanding of what this concept represents. A universal definition for healthcare settings and professionals is missing from published literature. Walker and Avant's approach was used to guide this concept analysis. Literature searches used bibliographic databases (Medline, CINAHL, Web of Science, Proquest CSA), internet search engines (GoogleScholar), and hand searches. Literature published between 1976 and 2006 was reviewed but only material in English was included. Based on the analysis undertaken, teamwork is proposed as a dynamic process involving two or more healthcare professionals with complementary backgrounds and skills, sharing common health goals and exercising concerted physical and mental effort in assessing, planning, or evaluating patient care. This is accomplished through interdependent collaboration, open communication and shared decision-making, and generates value-added patient, organizational and staff outcomes. Praising the value of teamwork without a common understanding of what this concept represents endangers both research into this way of working and its effective utilization in practice. The proposed definition helps reconcile discrepancies between how this concept is understood by nurses and doctors, as well as allied health professionals. A common understanding can facilitate communication in educational, research and clinical settings and is imperative for improving clarity and validity of future research.

  20. Dependence as a unifying construct in defining Alzheimer’s disease severity

    PubMed Central

    McLaughlin, Trent; Feldman, Howard; Fillit, Howard; Sano, Mary; Schmitt, Frederick; Aisen, Paul; Leibman, Christopher; Mucha, Lisa; Ryan, J. Michael; Sullivan, Sean D.; Spackman, D. Eldon; Neumann, Peter J.; Cohen, Joshua; Stern, Yaakov

    2012-01-01

    This article reviews measures of Alzheimer’s disease (AD) progression in relation to patient dependence and offers a unifying conceptual framework for dependence in AD. Clinicians typically characterize AD by symptomatic impairments in three domains: cognition, function, and behavior. From a patient’s perspective, changes in these domains, individually and in concert, ultimately lead to increased dependence and loss of autonomy. Examples of dependence in AD range from a need for reminders (early AD) to requiring safety supervision and assistance with basic functions (late AD). Published literature has focused on the clinical domains as somewhat separate constructs and has given limited attention to the concept of patient dependence as a descriptor of AD progression. This article presents the concept of dependence on others for care needs as a potential method for translating the effect of changes in cognition, function, and behavior into a more holistic, transparent description of AD progression. PMID:21044778

  1. The Microcircuit Concept Applied to Cortical Evolution: from Three-Layer to Six-Layer Cortex

    PubMed Central

    Shepherd, Gordon M.

    2011-01-01

    Understanding the principles of organization of the cerebral cortex requires insight into its evolutionary history. This has traditionally been the province of anatomists, but evidence regarding the microcircuit organization of different cortical areas is providing new approaches to this problem. Here we use the microcircuit concept to focus first on the principles of microcircuit organization of three-layer cortex in the olfactory cortex, hippocampus, and turtle general cortex, and compare it with six-layer neocortex. From this perspective it is possible to identify basic circuit elements for recurrent excitation and lateral inhibition that are common across all the cortical regions. Special properties of the apical dendrites of pyramidal cells are reviewed that reflect the specific adaptations that characterize the functional operations in the different regions. These principles of microcircuit function provide a new approach to understanding the expanded functional capabilities elaborated by the evolution of the neocortex. PMID:21647397

  2. Acute ankle sprain in dancers.

    PubMed

    Russell, Jeffrey A

    2010-01-01

    Ankle sprain is a common injury in dancers. Because of the relative frequency of this injury and its wide acceptance as a likely part of an active lifestyle, in many individuals it may not receive the careful attention it deserves. An extreme ankle range of motion and excellent ankle stability are fundamental to success in dance. Hence, following a proper treatment protocol is crucial for allowing a dancer who suffers an ankle sprain to return to dance as soon as possible without impaired function. This article reviews the basic principles of the etiology and management of ankle sprain in dancers. Key concepts are on-site examination and treatment, early restoration, dance-specific rehabilitation, and a carefully administered safe return to dance. Additionally, injuries that may occur in conjunction with ankle sprain are highlighted, and practical, clinically relevant summary concepts for dance healthcare professionals, dance scientists, dance teachers, and dancers are provided.

  3. Dependence as a unifying construct in defining Alzheimer's disease severity.

    PubMed

    McLaughlin, Trent; Feldman, Howard; Fillit, Howard; Sano, Mary; Schmitt, Frederick; Aisen, Paul; Leibman, Christopher; Mucha, Lisa; Ryan, J Michael; Sullivan, Sean D; Spackman, D Eldon; Neumann, Peter J; Cohen, Joshua; Stern, Yaakov

    2010-11-01

    This article reviews measures of Alzheimer's disease (AD) progression in relation to patient dependence and offers a unifying conceptual framework for dependence in AD. Clinicians typically characterize AD by symptomatic impairments in three domains: cognition, function, and behavior. From a patient's perspective, changes in these domains, individually and in concert, ultimately lead to increased dependence and loss of autonomy. Examples of dependence in AD range from a need for reminders (early AD) to requiring safety supervision and assistance with basic functions (late AD). Published literature has focused on the clinical domains as somewhat separate constructs and has given limited attention to the concept of patient dependence as a descriptor of AD progression. This article presents the concept of dependence on others for care needs as a potential method for translating the effect of changes in cognition, function, and behavior into a more holistic, transparent description of AD progression. Copyright © 2010. Published by Elsevier Inc.

  4. Getting a head start: the importance of personal genetics education in high schools.

    PubMed

    Kung, Johnny T; Gelbart, Marnie E

    2012-03-01

    With advances in sequencing technology, widespread and affordable genome sequencing will soon be a reality. However, studies suggest that "genetic literacy" of the general public is inadequate to prepare our society for this unprecedented access to our genetic information. As the current generation of high school students will come of age in an era when personal genetic information is increasingly utilized in health care, it is of vital importance to ensure these students understand the genetic concepts necessary to make informed medical decisions. These concepts include not only basic scientific knowledge, but also considerations of the ethical, legal, and social issues that will arise in the age of personal genomics. In this article, we review the current state of genetics education, highlight issues that we believe need to be addressed in a comprehensive genetics education curriculum, and describe our education efforts at the Harvard Medical School-based Personal Genetics Education Project.

  5. Measuring sports injuries on the pitch: a guide to use in practice

    PubMed Central

    Hespanhol, Luiz C.; Barboza, Saulo D.; van Mechelen, Willem; Verhagen, Evert

    2015-01-01

    Sports participation is a major ally for the promotion of physical activity. However, sports injuries are important adverse effects of sports participation and should be monitored in sports populations. The purpose of this paper is to review the basic concepts of injury monitoring and discuss the implementation of these concepts in practice. The aspects discussed are: (1) sports injury definition; (2) classification of sports injuries; (3) population at risk, prevalence, and incidence; (4) severity measures; (5) economic costs; (6) systems developed to monitor sports injuries; and (7) online technology. Only with reliable monitoring systems applied in a continuous and long-term manner will it be possible to identify the burden of injuries, to identify the possible cases at an early stage, to implement early interventions, and to generate data for sports injury prevention. The implementation of sports injuries monitoring systems in practice is strongly recommended. PMID:26537807

  6. Bioreactor concepts for cell culture-based viral vaccine production.

    PubMed

    Gallo-Ramírez, Lilí Esmeralda; Nikolay, Alexander; Genzel, Yvonne; Reichl, Udo

    2015-01-01

    Vaccine manufacturing processes are designed to meet present and upcoming challenges associated with a growing vaccine market and to include multi-use facilities offering a broad portfolio and faster reaction times in case of pandemics and emerging diseases. The final products, from whole viruses to recombinant viral proteins, are very diverse, making standard process strategies hardly universally applicable. Numerous factors such as cell substrate, virus strain or expression system, medium, cultivation system, cultivation method, and scale need consideration. Reviewing options for efficient and economical production of human vaccines, this paper discusses basic factors relevant for viral antigen production in mammalian cells, avian cells and insect cells. In addition, bioreactor concepts, including static systems, single-use systems, stirred tanks and packed-beds are addressed. On this basis, methods towards process intensification, in particular operational strategies, the use of perfusion systems for high product yields, and steps to establish continuous processes are introduced.

  7. The lack of a big picture in tuberculosis: the clinical point of view, the problems of experimental modeling and immunomodulation. The factors we should consider when designing novel treatment strategies

    PubMed Central

    Vilaplana, Cristina; Cardona, Pere-Joan

    2014-01-01

    This short review explores the large gap between clinical issues and basic science, and suggests why tuberculosis research should focus on redirect the immune system and not only on eradicating Mycobacterium tuberculosis bacillus. Along the manuscript, several concepts involved in human tuberculosis are explored in order to understand the big picture, including infection and disease dynamics, animal modeling, liquefaction, inflammation and immunomodulation. Scientists should take into account all these factors in order to answer questions with clinical relevance. Moreover, the inclusion of the concept of a strong inflammatory response being required in order to develop cavitary tuberculosis disease opens a new field for developing new therapeutic and prophylactic tools in which destruction of the bacilli may not necessarily be the final goal. PMID:24592258

  8. The lack of a big picture in tuberculosis: the clinical point of view, the problems of experimental modeling and immunomodulation. The factors we should consider when designing novel treatment strategies.

    PubMed

    Vilaplana, Cristina; Cardona, Pere-Joan

    2014-01-01

    This short review explores the large gap between clinical issues and basic science, and suggests why tuberculosis research should focus on redirect the immune system and not only on eradicating Mycobacterium tuberculosis bacillus. Along the manuscript, several concepts involved in human tuberculosis are explored in order to understand the big picture, including infection and disease dynamics, animal modeling, liquefaction, inflammation and immunomodulation. Scientists should take into account all these factors in order to answer questions with clinical relevance. Moreover, the inclusion of the concept of a strong inflammatory response being required in order to develop cavitary tuberculosis disease opens a new field for developing new therapeutic and prophylactic tools in which destruction of the bacilli may not necessarily be the final goal.

  9. Death, dignity, and moral nonsense.

    PubMed

    Pullman, Daryl

    2004-01-01

    Although the concept of human dignity is widely invoked in discussions regarding end-of-life decision making, the content of the notion is ambiguous. Such ambiguity has led some to conclude that human dignity is a redundant or even useless concept that we would be better off without. This paper argues, to the contrary, that the concept of human dignity is indispensable to moral discourse. Far from dispensing with human dignity, we must work to clarify the concept. The paper outlines two distinct but related conceptions of dignity that are often conflated in contemporary moral discourse. These conceptions are labelled "basic dignity" and "personal dignity", respectively. It is argued that basic dignity functions as a universal meaning constraint on moral discourse in general. Hence, to dispense with the notion could reduce us to speaking moral nonsense. Throughout the discussion, some implications for our understanding of end-of-life decision making are explored.

  10. Health as a basic human need: would this be enough?

    PubMed

    de Campos, Thana Cristina

    2012-01-01

    Although the value of health is universally agreed upon, its definition is not. Both the WHO and the UN define health in terms of well-being. They advocate a globally shared responsibility that all of us - states, international organizations, pharmaceutical corporations, civil society, and individuals - bear for the health (that is, the well-being) of the world's population. In this paper I argue that this current well-being conception of health is troublesome. Its problem resides precisely in the fact that the well-being conception of health, as an all-encompassing label, does not properly distinguish between the different realities of health and the different demands of justice, which arise in each case. In addressing responsibilities related to the right to health, we need to work with a more differentiated vocabulary, which can account for these different realities. A crucial distinction to bear in mind, for the purposes of moral deliberation and the crafting of political and legal institutions, is the difference between basic and non-basic health needs. This distinction is crucial because we have presumably more stringent obligations and rights in relation to human needs that are basic, as they justify stronger moral claims, than those grounded on non-basic human needs. It is important to keep this moral distinction in mind because many of the world's problems regarding the right to health relate to basic health needs. By conflating these needs with less essential ones, we risk confusing different types of moral claims and weakening the overall case for establishing duties regarding the right to health. There is, therefore, a practical need to reevaluate the current normative conception of health so that it distinguishes, within the broad scope of well-being, between what is basic and what is not. My aim here is to shed light onto this distinction and to show the need for this differentiation. I do so, first, by providing, on the basis of David Miller's concept of basic needs, an account of basic health needs and, secondly, by mounting a defense of the basic needs approach to the right to health, arguing against James Griffin who opposes the basic needs approach. © 2012 American Society of Law, Medicine & Ethics, Inc.

  11. [Nurse's concept in the managerial conception of a basic health unit].

    PubMed

    Passos, Joanir Pereira; Ciosak, Suely Itsuko

    2006-12-01

    This study is part of a larger survey called "Use of indicators in nurses' managerial practice in Basic Health Care Units in the city of Rio de Janeiro", which was carried out in the Basic Health Care Units of the Planning Area 5.3 and whose objectives were to identify nurses' conception regarding the tools required for management in those units and to discuss the role of management in organizing health services. The study is descriptive and data were collected in interviews with seven nurse managers. The results show that health services actions are organized and directed to the purpose of the working process through the relationship established between the object, the instruments and the final product, and that for those nurses the end result to be achieved is client's satisfaction and the quality of medical and nursing care.

  12. Basic Emotions in Human Neuroscience: Neuroimaging and Beyond.

    PubMed

    Celeghin, Alessia; Diano, Matteo; Bagnis, Arianna; Viola, Marco; Tamietto, Marco

    2017-01-01

    The existence of so-called 'basic emotions' and their defining attributes represents a long lasting and yet unsettled issue in psychology. Recently, neuroimaging evidence, especially related to the advent of neuroimaging meta-analytic methods, has revitalized this debate in the endeavor of systems and human neuroscience. The core theme focuses on the existence of unique neural bases that are specific and characteristic for each instance of basic emotion. Here we review this evidence, outlining contradictory findings, strengths and limits of different approaches. Constructionism dismisses the existence of dedicated neural structures for basic emotions, considering that the assumption of a one-to-one relationship between neural structures and their functions is central to basic emotion theories. While these critiques are useful to pinpoint current limitations of basic emotions theories, we argue that they do not always appear equally generative in fostering new testable accounts on how the brain relates to affective functions. We then consider evidence beyond PET and fMRI, including results concerning the relation between basic emotions and awareness and data from neuropsychology on patients with focal brain damage. Evidence from lesion studies are indeed particularly informative, as they are able to bring correlational evidence typical of neuroimaging studies to causation, thereby characterizing which brain structures are necessary for, rather than simply related to, basic emotion processing. These other studies shed light on attributes often ascribed to basic emotions, such as automaticity of perception, quick onset, and brief duration. Overall, we consider that evidence in favor of the neurobiological underpinnings of basic emotions outweighs dismissive approaches. In fact, the concept of basic emotions can still be fruitful, if updated to current neurobiological knowledge that overcomes traditional one-to-one localization of functions in the brain. In particular, we propose that the structure-function relationship between brain and emotions is better described in terms of pluripotentiality, which refers to the fact that one neural structure can fulfill multiple functions, depending on the functional network and pattern of co-activations displayed at any given moment.

  13. Cause and Effect: Testing a Mechanism and Method for the Cognitive Integration of Basic Science.

    PubMed

    Kulasegaram, Kulamakan; Manzone, Julian C; Ku, Cheryl; Skye, Aimee; Wadey, Veronica; Woods, Nicole N

    2015-11-01

    Methods of integrating basic science with clinical knowledge are still debated in medical training. One possibility is increasing the spatial and temporal proximity of clinical content to basic science. An alternative model argues that teaching must purposefully expose relationships between the domains. The authors compared different methods of integrating basic science: causal explanations linking basic science to clinical features, presenting both domains separately but in proximity, and simply presenting clinical features First-year undergraduate health professions students were randomized to four conditions: (1) science-causal explanations (SC), (2) basic science before clinical concepts (BC), (3) clinical concepts before basic science (CB), and (4) clinical features list only (FL). Based on assigned conditions, participants were given explanations for four disorders in neurology or rheumatology followed by a memory quiz and diagnostic test consisting of 12 cases which were repeated after one week. Ninety-four participants completed the study. No difference was found on memory test performance, but on the diagnostic test, a condition by time interaction was found (F[3,88] = 3.05, P < .03, ηp = 0.10). Although all groups had similar immediate performance, the SC group had a minimal decrease in performance on delayed testing; the CB and FL groups had the greatest decreases. These results suggest that creating proximity between basic science and clinical concepts may not guarantee cognitive integration. Although cause-and-effect explanations may not be possible for all domains, making explicit and specific connections between domains will likely facilitate the benefits of integration for learners.

  14. 48 CFR 801.602-71 - Basic review requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Basic review requirements... GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority, and Responsibilities 801.602-71 Basic review requirements. Contracting officers must obtain...

  15. A basic recursion concept inventory

    NASA Astrophysics Data System (ADS)

    Hamouda, Sally; Edwards, Stephen H.; Elmongui, Hicham G.; Ernst, Jeremy V.; Shaffer, Clifford A.

    2017-04-01

    Recursion is both an important and a difficult topic for introductory Computer Science students. Students often develop misconceptions about the topic that need to be diagnosed and corrected. In this paper, we report on our initial attempts to develop a concept inventory that measures student misconceptions on basic recursion topics. We present a collection of misconceptions and difficulties encountered by students when learning introductory recursion as presented in a typical CS2 course. Based on this collection, a draft concept inventory in the form of a series of questions was developed and evaluated, with the question rubric tagged to the list of misconceptions and difficulties.

  16. Representing the "Other": Basic Writers and the Teaching of Basic Writing. Refiguring English Studies.

    ERIC Educational Resources Information Center

    Horner, Bruce; Lu, Min-Zhan

    Intended for teachers of basic writing, this book contains a collection of new and updated essays addressing issues surrounding underprepared writers. It maps errors and expectations for basic writing and develops teaching approaches that will be effective in a social and political world. The book considers concepts such as the possibility of…

  17. Basic Science Living Skills for Today's World. Teacher's Edition.

    ERIC Educational Resources Information Center

    Zellers (Robert W.) Educational Services, Johnstown, PA.

    This document is a teacher's edition of a basic skills curriculum in science for adult basic education (ABE) students. The course consists of 25 lessons on basic science concepts, designed to give students a good understanding of the biological and physical sciences. Suggested activities and experiments that the student can do are also included.…

  18. Rationalising Sports Policies: I. Outline of a Methodology. European Cooperation For the Development of Sport for All.

    ERIC Educational Resources Information Center

    Paz, Benito Castejon; And Others

    The major aim of this study is to devise a model for rationalizing sports policies by defining the basic concepts that should be inherent in any proper sports policy despite the infinite diversity that characterizes actual sport situations. The first part of the study discusses three concepts which are basic to the model: a) the "level of sport"…

  19. Control of Breathing During Mechanical Ventilation: Who Is the Boss?

    PubMed Central

    Williams, Kathleen; Hinojosa-Kurtzberg, Marina; Parthasarathy, Sairam

    2011-01-01

    Over the past decade, concepts of control of breathing have increasingly moved from being theoretical concepts to “real world” applied science. The purpose of this review is to examine the basics of control of breathing, discuss the bidirectional relationship between control of breathing and mechanical ventilation, and critically assess the application of this knowledge at the patient’s bedside. The principles of control of breathing remain under-represented in the training curriculum of respiratory therapists and pulmonologists, whereas the day-to-day bedside application of the principles of control of breathing continues to suffer from a lack of outcomes-based research in the intensive care unit. In contrast, the bedside application of the principles of control of breathing to ambulatory subjects with sleep-disordered breathing has out-stripped that in critically ill patients. The evolution of newer technologies, faster real-time computing abilities, and miniaturization of ventilator technology can bring the concepts of control of breathing to the bedside and benefit the critically ill patient. However, market forces, lack of scientific data, lack of research funding, and regulatory obstacles need to be surmounted. PMID:21333174

  20. Experiencing Economic Concepts: Formal and Informal Concept Learning.

    ERIC Educational Resources Information Center

    Armento, Beverly Jeanne

    1980-01-01

    This article discusses the feasibility of and the skills needed for teaching basic economic concepts such as supply and demand in an informal learning situation, in this case the simulation of an economic system based on barter. (CJ)

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