A duck enteritis virus-vectored bivalent live vaccine provides fast and complete protection against H5N1 avian influenza virus infection in ducks.

PubMed

Liu, Jinxiong; Chen, Pucheng; Jiang, Yongping; Wu, Li; Zeng, Xianying; Tian, Guobin; Ge, Jinying; Kawaoka, Yoshihiro; Bu, Zhigao; Chen, Hualan

2011-11-01

Ducks play an important role in the maintenance of highly pathogenic H5N1 avian influenza viruses (AIVs) in nature, and the successful control of AIVs in ducks has important implications for the eradication of the disease in poultry and its prevention in humans. The inactivated influenza vaccine is expensive, labor-intensive, and usually needs 2 to 3 weeks to induce protective immunity in ducks. Live attenuated duck enteritis virus (DEV; a herpesvirus) vaccine is used routinely to control lethal DEV infections in many duck-producing areas. Here, we first established a system to generate the DEV vaccine strain by using the transfection of overlapping fosmid DNAs. Using this system, we constructed two recombinant viruses, rDEV-ul41HA and rDEV-us78HA, in which the hemagglutinin (HA) gene of the H5N1 virus A/duck/Anhui/1/06 was inserted and stably maintained within the ul41 gene or between the us7 and us8 genes of the DEV genome. Duck studies indicated that rDEV-us78HA had protective efficacy similar to that of the live DEV vaccine against lethal DEV challenge; importantly, a single dose of 10(6) PFU of rDEV-us78HA induced complete protection against a lethal H5N1 virus challenge in as little as 3 days postvaccination. The protective efficacy against both lethal DEV and H5N1 challenge provided by rDEV-ul41HA inoculation in ducks was slightly weaker than that provided by rDEV-us78HA. These results demonstrate, for the first time, that recombinant DEV is suitable for use as a bivalent live attenuated vaccine, providing rapid protection against both DEV and H5N1 virus infection in ducks.

DevS Oxy Complex Stability Identifies this Heme Protein as a Gas Sensor in Mycobacterium tuberculosis Dormancy†

PubMed Central

Ioanoviciu, Alexandra; Meharenna, Yergalem T.; Poulos, Thomas L.; Ortiz de Montellano, Paul R.

2009-01-01

DevS is one of the two sensing kinases responsible for DevR activation and the subsequent entry of Mycobacterium tuberculosis into dormancy. Full length wild-type DevS forms a stable oxy-ferrous complex. The DevS autooxidation rates are extremely low (half-lives > 24 h) in the presence of cations such as K+, Na+, Mg2+, and Ca2+. At relatively high concentrations (100 µM), Fe3+ mildly increases the autooxidation rate (six-fold increase) while Cu2+ accelerates autooxidation more than 1500-fold. Contrary to expectations, removal of the key hydrogen bond between the iron-coordinated oxygen and Tyr171 in the Y171F mutant provides a protein of comparable stability to autooxidation and similar oxygen dissociation rate. This correlates with our earlier finding that the Y171F mutant and wild-type kinase activities are similarly regulated by the binding of oxygen: namely, the ferrous 5c complex is active whereas the oxy ferrous 6c species is inactive. Our results indicate that DevS is a gas sensor in vivo rather than a redox sensor and that the stability of its ferrous-oxy complex is enhanced by inter-domain interactions. PMID:19463006

Soldiers Magazine | Telling the Soldier's story

Science.gov Websites

mission Saving 1st Sgt. Jackson, part 2: A life rebuilt A suicidal first sergeant finds the strength to get help for PTSD and reclaim his life. (DoD graphic by Peggy Frierson) Saving 1st Sgt. Jackson, part 2: A life rebuilt Saving 1st Sgt. Jackson, part 2: A life rebuilt Saving 1st Sgt. Jackson part 1: A

77 FR 13126 - Corporation to do Business Under Section 25A of the Federal Reserve Act

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-05

... in acting on the application are set forth in the Board's Regulation K (12 CFR 211.4). The... Federal Reserve Act (Edge Corporation) 12 U.S.C. 611 et seq., and all other applicable statutes and.... Frierson, Deputy Secretary of the Board. [FR Doc. 2012-5268 Filed 3-2-12; 8:45 am] BILLING CODE 6210-01-P ...

Maintenance Operations Degradation of Airfield Pavement Markings

DTIC Science & Technology

2012-03-01

polyurea . 1.4 Research Questions To answer the problem presented, several questions need to be addressed. The first is whether or not rubber...suitable for use on airfields.  Further research is required. Cyrus and Frierson 2006 Polyurea  The material showed poor performance in...evaluating polyurea and one evaluating polyester. Both studies were undertaken to evaluate the effectiveness of polyurea or polyester as a potential

77 FR 30292 - Corporation To Do Business Under Section 25A of the Federal Reserve Act

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-22

... Regulation K (12 CFR 211.4). The application below, as well as other related filings required by the Board... Federal Reserve Act (Edge Corporation) 12 U.S.C. Sec. 611 et seq., and all other applicable statutes and.... Frierson, Deputy Secretary of the Board. [FR Doc. 2012-12348 Filed 5-21-12; 8:45 am] BILLING CODE 6210-01-P ...

Inventory of File sref.t03z.pgrb212.spread_3hrly.grib2

Science.gov Websites

ground UGRD analysis U-Component of Wind [m/s] std dev 002 10 m above ground VGRD analysis V-Component of Wind [m/s] std dev 003 1000 mb UGRD analysis U-Component of Wind [m/s] std dev 004 850 mb UGRD analysis U-Component of Wind [m/s] std dev 005 700 mb UGRD analysis U-Component of Wind [m/s] std dev 006 600

Inventory of File sref.t03z.pgrb216.spread_3hrly.grib2

Science.gov Websites

ground UGRD analysis U-Component of Wind [m/s] std dev 002 10 m above ground VGRD analysis V-Component of Wind [m/s] std dev 003 1000 mb UGRD analysis U-Component of Wind [m/s] std dev 004 850 mb UGRD analysis U-Component of Wind [m/s] std dev 005 700 mb UGRD analysis U-Component of Wind [m/s] std dev 006 600

Inventory of File sref.t03z.pgrb243.spread_3hrly.grib2

Science.gov Websites

ground UGRD analysis U-Component of Wind [m/s] std dev 002 10 m above ground VGRD analysis V-Component of Wind [m/s] std dev 003 1000 mb UGRD analysis U-Component of Wind [m/s] std dev 004 850 mb UGRD analysis U-Component of Wind [m/s] std dev 005 700 mb UGRD analysis U-Component of Wind [m/s] std dev 006 600

Inventory of File sref.t03z.pgrb132.spread_3hrly.grib2

Science.gov Websites

ground UGRD analysis U-Component of Wind [m/s] std dev 002 10 m above ground VGRD analysis V-Component of Wind [m/s] std dev 003 1000 mb UGRD analysis U-Component of Wind [m/s] std dev 004 850 mb UGRD analysis U-Component of Wind [m/s] std dev 005 700 mb UGRD analysis U-Component of Wind [m/s] std dev 006 600

The Army Communications Objectives Measurement System (ACOMS): Codebook for the Message Content Analysis Data File

DTIC Science & Technology

1988-07-01

0.1 400 SELF-DEVELOPMENT 176 4.8 420 DEV SELF-CONFID 15 0.4 430 DEV MATURE PERSN a 0.2 440 DEV POTENTIAL 367 10.0 450 ADVTG OVER COLLG 23 0.6 471 DEV...OVER COLLG 22 0.6 471 DEV DISCIPLINE it 0.3 481 DEVELOP PRIDE 7 0.2 500 MONEY/BENEFITS 116 3.2 600 EDUC/BENEFITS 279 7.6 700 TRAVEL 43 1.2 821 ADVENTURE...OVER COLLG 9 0.2 460 WRK HITRAIN PEOP 1 0.0 471 DEV DISCIPLINE 7 0.2 491 DEVELOP PRIDE 4 0.1 500 MONEY/BENEFITS 40 1.1 600 EDUC/BENEFITS 90 2.5 700

Driver's Enhanced Vision System (DEVS)

DOT National Transportation Integrated Search

1996-12-23

This advisory circular (AC) contains performance standards, specifications, and : recommendations for Drivers Enhanced Vision sSystem (DEVS). The FAA recommends : the use of the guidance in this publication for the design and installation of : DEVS e...

Software Sustainment -- Now and Future

DTIC Science & Technology

2014-01-01

today the commercial environment is using something referred to as DevOps . What is DevOps ? What it is. A way of working that encourages the Develop...section. However, there are some major differences. DevOps seems to be the Agile community’s term for doing sustainment and opera- tions in parallel...methods in sustainment within the federal government. This research is how I came upon the term DevOps . In addition, Gene Kim provided a keynote

From Domain Specific Languages to DEVS Components: Application to Cognitive M&S

DTIC Science & Technology

2011-04-01

AND SUBTITLE From Domain Specific Languages to DEVS Components: Application to Cognitive M&S 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ...that is devoid of any DEVS and programming language constructs (Figure 4). The key idea being domain specialists need not delve in the DEVS world to...DSL. DSLs can be created using many available tools and technologies such as: Generic Modeling Environment (GME) [23], Xtext, Ruby, Scala and many

Inventory of File sref.t03z.pgrb197.spread_ds_3hrly.grib2

Science.gov Websites

3 hour fcst U-Component of Wind [m/s] std dev 002 10 m above ground VGRD 3 hour fcst V-Component of Wind [m/s] std dev 003 2 m above ground TMP 3 hour fcst Temperature [K] std dev 004 2 m above ground SPFH 3 hour fcst Specific Humidity [kg/kg] std dev 005 10 m above ground WIND 3 hour fcst Wind Speed [m

Characterization and genome sequence of Dev2, a new T7-like bacteriophage infecting Cronobacter turicensis.

PubMed

Kajsík, Michal; Oslanecová, Lucia; Szemes, Tomáš; Hýblová, Michalea; Bilková, Andrea; Drahovská, Hana; Turňa, Ján

2014-11-01

Cronobacter spp. are opportunistic pathogenic bacteria that are responsible for severe infections in neonates. Powdered infant formula was confirmed to be the source in some cases. Bacteriophages offer a safe means for eliminating this pathogen. In the present study, we investigated the growth parameters and genome organization of a new bacteriophage, Dev2, isolated from sewage. The Dev2 phage contains DNA with a length of 39 kb and belongs to the T7 branch of the subfamily Autographivirinae, with the highest degree of identity to the phage K1F. The host specificity of Dev2 is limited to C. turicensis strains of the CT O:1 serotype. With a lower efficiency, this phage also infects some Salmonella and E. coli strains. The Dev2 phage can inactivate sensitive Cronobacter strains in reconstituted milk formula. The results obtained in this study are an important prerequisite for application of Dev2 in food control.

Inventory of File sref.t03z.pgrb212.spread_1hrly.grib2

Science.gov Websites

UGRD 1 hour fcst U-Component of Wind [m/s] std dev 002 10 m above ground VGRD 1 hour fcst V-Component of Wind [m/s] std dev 003 1000 mb UGRD 1 hour fcst U-Component of Wind [m/s] std dev 004 850 mb UGRD 1 hour fcst U-Component of Wind [m/s] std dev 005 700 mb UGRD 1 hour fcst U-Component of Wind [m/s

A systemic approach for modeling biological evolution using Parallel DEVS.

PubMed

Heredia, Daniel; Sanz, Victorino; Urquia, Alfonso; Sandín, Máximo

2015-08-01

A new model for studying the evolution of living organisms is proposed in this manuscript. The proposed model is based on a non-neodarwinian systemic approach. The model is focused on considering several controversies and open discussions about modern evolutionary biology. Additionally, a simplification of the proposed model, named EvoDEVS, has been mathematically described using the Parallel DEVS formalism and implemented as a computer program using the DEVSLib Modelica library. EvoDEVS serves as an experimental platform to study different conditions and scenarios by means of computer simulations. Two preliminary case studies are presented to illustrate the behavior of the model and validate its results. EvoDEVS is freely available at http://www.euclides.dia.uned.es. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Expression and distribution of the duck enteritis virus UL51 protein in experimentally infected ducks.

PubMed

Shen, Chanjuan; Cheng, Anchun; Wang, Mingshu; Xu, Chao; Jia, Renyong; Chen, Xiaoyue; Zhu, Dekang; Luo, Qihui; Cui, Hengmin; Zhou, Yi; Wang, Yin; Xu, Zhiwen; Chen, Zhengli; Wang, Xiaoyu

2010-06-01

To determine the expression and distribution of tegument proteins encoded by duck enteritis virus (DEV) UL51 gene in tissues of experimentally infected ducks, for the first time, an immunoperoxidase staining method to detect UL51 protein (UL51p) in paraffin-embedded tissues is reported. A rabbit anti-UL51 polyclonal serum, raised against a recombinant 6-His-UL51 fusion protein expressed in Escherichia coli, was prepared, purified, and used as primary antibodies. Fifty-eight 30-day-old DEV-free ducks were intramuscularly inoculated with the pathogenic DEV CHv strain as infection group, and two ducks were selected as preinfection group. The tissues were collected at sequential time points between 2 and 480 hr postinoculation (PI) and prepared for immunoperoxidase staining. DEV UL51p was first found in the spleen and liver at 8 hr PI; in the bursa of Fabricius and thymus at 12 hr PI; in the Harders glands, esophagus, small intestine (including the duodenum, jejunum, and ileum), and large intestine (including the caecum and rectum) at 24 hr PI; in the glandularis ventriculus at 48 hr PI; and in the pancreas, cerebrum, kidney, lung, and myocardium at 72 hr PI. Throughout the infection process, the UL51p was not seen in the muscle. Furthermore, the intensity of positive staining of DEV UL51p antigen in various tissues increased sharply from 8 to 96 hr PI, peaked during 120-144 hr PI, and then decreased steadily from 216 to 480 hr PI, suggesting that the expressional levels of DEV UL51p in systemic organs have a close correlation with the progression of duck virus enteritis (DVE) disease. A number of DEV UL51p was distributed in the bursa of Fabricius, thymus, spleen, liver, esophagus, small intestine, and large intestine of DEV-infected ducks, whereas less DEV UL51p was distributed in the Harders glands, glandularis ventriculus, cerebrum, kidney, lung, pancreas, and myocardium of DEV-infected ducks. Moreover, DEV UL51p can be expressed in the cytoplasm of various types of cells, especially most abundantly in the cytoplasm of lymphocytes, reticulum cells, macrophages, epithelial cells, and hepatocytes. The present study may be useful not only for describing the characteristics of UL51p expression and distribution in vivo but also for a greater understanding of the pathogenesis of this DVE.

Association between Antioxidant Enzyme Activities and Enterovirus-Infected Type 1 Diabetic Children.

PubMed

Abdel-Moneim, Adel; El-Senousy, Waled M; Abdel-Latif, Mahmoud; Khalil, Rehab G

2018-01-01

To examine the effect of infection with Enterovirus (EV) in children with type 1 diabetes (T1D) on the activities of serum antioxidant enzymes in diabetic and nondiabetic controls. Three hundred and eighty-two diabetic and 100 nondiabetic children were tested for EV RNA using reverse transcriptase (RT)-PCR. The activities of serum superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) were also estimated in diabetic patients infected with EV (T1D-EV+), those not infected with EV (T1D-EV-), and in nondiabetic controls. The frequency of EV was higher in diabetic children (100/382; 26.2%) than in healthy controls (0/100). Levels of fasting blood glucose (FBG), glycosylated hemoglobin (HbA1c) and C-reactive protein (CRP) were significantly higher but C-peptide was significantly lower in diabetic children than in controls. CRP levels were higher in the T1D-EV+ group than in the T1D-EV- group, and higher in all diabetic children than in nondiabetic controls. The activities of the antioxidant enzymes GPx, SOD, and CAT decreased significantly in diabetic children compared to in controls. Moreover, the activities of the enzymes tested were significantly reduced in the T1D-EV+ group compared to in the T1D-EV- group. Our data indicate that EV infection correlated with a decrease in the activity of antioxidant enzymes in the T1D-EV+ group compared to in the T1D-EV- group; this may contribute to β cell damage and increased inflammation. © 2018 The Author(s) Published by S. Karger AG, Basel.

PDB-Dev: a Prototype System for Depositing Integrative/Hybrid Structural Models.

PubMed

Burley, Stephen K; Kurisu, Genji; Markley, John L; Nakamura, Haruki; Velankar, Sameer; Berman, Helen M; Sali, Andrej; Schwede, Torsten; Trewhella, Jill

2017-09-05

Burley et al. (leadership of the Worldwide PDB [wwPDB] Partnership [wwpdb.org] and the wwPDB Integrative/Hybrid Methods Task Force) announce public release of a prototype system for depositing integrative/hybrid structural models, PDB-Development (PDB-Dev; https://pdb-dev.wwpdb.org). Copyright © 2017. Published by Elsevier Ltd.

IT Software Development and IT Operations Strategic Alignment: An Agile DevOps Model

ERIC Educational Resources Information Center

Hart, Michael

2017-01-01

Information Technology (IT) departments that include development and operations are essential to develop software that meet customer needs. DevOps is a term originally constructed from software development and IT operations. DevOps includes the collaboration of all stakeholders such as software engineers and systems administrators involved in the…

DEVS representation of dynamical systems - Event-based intelligent control. [Discrete Event System Specification

NASA Technical Reports Server (NTRS)

Zeigler, Bernard P.

1989-01-01

It is shown how systems can be advantageously represented as discrete-event models by using DEVS (discrete-event system specification), a set-theoretic formalism. Such DEVS models provide a basis for the design of event-based logic control. In this control paradigm, the controller expects to receive confirming sensor responses to its control commands within definite time windows determined by its DEVS model of the system under control. The event-based contral paradigm is applied in advanced robotic and intelligent automation, showing how classical process control can be readily interfaced with rule-based symbolic reasoning systems.

A "Research" into International Student-Related Research: (Re)visualising Our Stand?

ERIC Educational Resources Information Center

Abdullah, Doria; Abd Aziz, Mohd Ismail; Mohd Ibrahim, Abdul Latiff

2014-01-01

This paper uses Tight ("High Educ Res Dev" 23(4):395-411, 2004; "High Educ Res Dev" 31(5):723-740, 2012; "High Educ Res Dev" 32(1):136-151, 2013)'s journal analysis and review framework to review a sample of 497 journal articles on researches concerning international students over the past 30 years. It was found…

Dynamic Self-Organization and Early Lexical Development in Children

ERIC Educational Resources Information Center

Li, Ping; Zhao, Xiaowei; Whinney, Brian Mac

2007-01-01

In this study we present a self-organizing connectionist model of early lexical development. We call this model DevLex-II, based on the earlier DevLex model. DevLex-II can simulate a variety of empirical patterns in children's acquisition of words. These include a clear vocabulary spurt, effects of word frequency and length on age of acquisition,…

Bioinformatics analysis and characteristics of VP23 encoded by the newly identified UL18 gene of duck enteritis virus

NASA Astrophysics Data System (ADS)

Chen, Xiwen; Cheng, Anchun; Wang, Mingshu; Xiang, Jun

2011-10-01

In this study, the predicted information about structures and functions of VP23 encoded by the newly identified DEV UL18 gene through bioinformatics softwares and tools. The DEV UL18 was predicted to encode a polypeptide with 322 amino acids, termed VP23, with a putative molecular mass of 35.250 kDa and a predicted isoelectric point (PI) of 8.37, no signal peptide and transmembrane domain in the polypeptide. The prediction of subcellular localization showed that the DEV-VP23 located at endoplasmic reticulum with 33.3%, mitochondrial with 22.2%, extracellular, including cell wall with 11.1%, vesicles of secretory system with 11.1%, Golgi with 11.1%, and plasma membrane with 11.1%. The acid sequence of analysis showed that the potential antigenic epitopes are situated in 45-47, 53-60, 102-105, 173-180, 185-189, 260-265, 267-271, and 292-299 amino acids. All the consequences inevitably provide some insights for further research about the DEV-VP23 and also provide a fundament for further study on the the new type clinical diagnosis of DEV and can be used for the development of new DEV vaccine.

Construction of a recombinant duck enteritis virus vaccine expressing hemagglutinin of H9N2 avian influenza virus and evaluation of its efficacy in ducks.

PubMed

Sun, Ying; Yang, Chenghuai; Li, Junping; Li, Ling; Cao, Minghui; Li, Qihong; Li, Huijiao

2017-01-01

H9 subtype avian influenza viruses (AIVs) remain a significant burden in the poultry industry and are considered to be one of the most likely causes of any new influenza pandemic in humans. As ducks play an important role in the maintenance of H9 viruses in nature, successful control of the spread of H9 AIVs in ducks will have significant beneficial effects on public health. Duck enteritis virus (DEV) may be a promising candidate viral vector for aquatic poultry vaccination. In this study, we constructed a recombinant DEV, rDEV-∆UL2-HA, inserting the hemagglutinin (HA) gene from duck-origin H9N2 AIV into the UL2 gene by homologous recombination. One-step growth analyses showed that the HA gene insertion had no effect on viral replication and suggested that the UL2 gene was nonessential for virus growth in vitro. In vivo tests further showed that the insertion of the HA gene in place of the UL2 gene did not affect the immunogenicity of the virus. Moreover, a single dose of 10 3 TCID 50 of rDEV-∆UL2-HA induced solid protection against lethal DEV challenge and completely prevented H9N2 AIV viral shedding. To our knowledge, this is the first report of a DEV-vectored vaccine providing robust protection against both DEV and H9N2 AIV virus infections in ducks.

Patient Engagement Programs for Recognition and Initial Treatment of Depression in Primary Care: A Randomized Trial

PubMed Central

Kravitz, Richard L.; Franks, Peter; Feldman, Mitchell D.; Tancredi, Daniel J.; Slee, Christina A.; Epstein, Ronald M.; Duberstein, Paul R.; Bell, Robert A.; Jackson-Triche, Maga; Paterniti, Debora A.; Cipri, Camille; Iosif, Ana-Maria; Olson, Sarah; Kelly-Reif, Steven; Hudnut, Andrew; Dvorak, Simon; Turner, Charles; Jerant, Anthony

2015-01-01

Importance Interventions encouraging primary care patients’ engagement with their clinicians to address depression could improve outcomes but foster unnecessary treatment. Objective Determine whether a depression engagement video (DEV) or a tailored interactive multimedia computer program (IMCP) improves initial depression care without increasing unnecessary anti-depressant prescribing. Design Randomized controlled trial comparing three interventions (DEV, IMCP, and control) conducted in two patients groups (depressed, defined by a Patient Health Questionnaire [PHQ]-9 score ≥5, and non-depressed [PHQ-9<5]) conducted between June 2010 and March 2012. Setting Primary care offices at 7 sites in 2 cities. Participants Depressed (N=559) and non-depressed (N=308) adult patients of 135 primary care clinicians. Intervention(s) DEV targeted to gender and income; IMCP tailored to individual patient characteristics; a sleep hygiene video (control). Main Outcome Measure(s) Depressed patients: composite measure of antidepressant recommendation and/or mental health referral (primary outcome); 12-week mental health, measured by the PHQ-8 (secondary outcome). Non- depressed patients: clinician-reported prescribing and patient-reported antidepressant recommendation (primary outcomes, pre-specified 3.5% non-inferiority margins). Results Depressed patients: composite care outcome rates were 18%, 26%, and 16% respectively in the DEV, IMCP, and control groups (cluster-adjusted DEV-control difference = 1.1% [95% CI −6.7 to 8.9, P=.79]; IMCP-control = 9.9% [95% CI 1.6 to 18.2, P=.02]). Twelve-week PHQ-8 effects were not significant: DEV- control = −0.2 points (95% CI −1.2 to 0.8); IMCP – control = 0.9 (95% CI −0.1 to 1.9). Non-depressed patients: clinician-reported antidepressant prescribing in the DEV and IMCP groups was non-inferior to control (DEV-control = −2.2%, 90% CI −8.0 to 3.498, non-inferiority (NI) P=.0499; IMCP-control = −3.3%, 90% CI −9.1 to 2.4, NI P=.02); patient-reported antidepressant recommendation did not achieve non-inferiority: DEV-control = 0.9% (90% CI −4.9 to 6.7; NI P=.23); IMCP-control = 0.3% (90% CI −5.1 to 5.7; NI P=.16). Conclusions and Relevance A tailored IMCP increased antidepressant recommendation and/or mental health referral among depressed patients but had no effect on 12-week mental health. The possibility that the IMCP and DEV increased patient-reported antidepressant recommendations among non-depressed patients could not be excluded. Further research is needed on the benefits and harms of these interventions. PMID:24193079

Distributed Generation Renewable Energy Estimate of Costs | Energy Analysis

Science.gov Websites

viability. Table 1 Costs for Electric Generating Technologies Technology Type Mean installed cost ($/kW ) Installed cost Std. Dev. (+/- $/kW) Fixed O&M ($/kW-yr) Fixed O&M Std. Dev. (+/- $/kW-yr) Variable O cost ($/kWh) Fuel and/or water Std. Dev. ($/kWh) PV <10 kW $3,897 $889 $21 $20 n/a n/a 33 11 n/a n/a

Distributed Generation Renewable Energy Estimate of Costs | Energy Analysis

Science.gov Websites

viability. Table 1 Costs for Electric Generating Technologies Technology Type Mean installed cost ($/kW ) Installed cost Std. Dev. (+/- $/kW) Fixed O&M ($/kW-yr) Fixed O&M Std. Dev. (+/- $/kW-yr) Variable O cost ($/kWh) Fuel and/or water Std. Dev. ($/kWh) PV <10 kW $3,910 $921 $21 $20 n/a n/a 33 11 n/a n/a

Inventory of File spread.sref.cluster1.f03.grib2

Science.gov Websites

Records: 40 Number Level/Layer Parameter Forecast Valid Description 001 2 m above ground TMP 3 hour fcst Temperature [K] std dev 002 2 m above ground TMP 3 hour fcst Temperature [K] std dev 003 2 m above ground SPFH 3 hour fcst Specific Humidity [kg/kg] std dev 004 2 m above ground RH 3 hour fcst Relative Humidity

Expression and characterization of duck enteritis virus gI gene

PubMed Central

2011-01-01

Background At present, alphaherpesviruses gI gene and its encoding protein have been extensively studied. It is likely that gI protein and its homolog play similar roles in virions direct cell-to-cell spread of alphaherpesviruses. But, little is known about the characteristics of DEV gI gene. In this study, we expressed and presented the basic properties of the DEV gI protein. Results The special 1221-bp fragment containing complete open reading frame(ORF) of duck enteritis virus(DEV) gI gene was extracted from plasmid pMD18-T-gI, and then cloned into prokaryotic expression vector pET-32a(+), resulting in pET-32a(+)-gI. After being confirmed by PCR, restriction endonuclease digestion and sequencing, pET-32a(+)-gI was transformed into E.coli BL21(DE3) competent cells for overexpression. DEV gI gene was successfully expressed by the addition of isopropyl-β-D-thiogalactopyranoside(IPTG). SDS-PAGE showed that the recombinant protein His6-tagged gI molecular weight was about 61 kDa. Subsequently, the expressed product was applied to generate specific antibody against gI protein. The specificity of the rabbit immuneserum was confirmed by its ability to react with the recombinant protein His6-tagged gI. In addition, real time-PCR was used to determine the the levels of the mRNA transcripts of gI gene, the results showed that the DEV gI gene was transcribed most abundantly during the late phase of infection. Furthermore, indirect immunofluorescence(IIF) was established to study the gI protein expression and localization in DEV-infected duck embryo fibroblasts (DEFs), the results confirmed that the protein was expressed and located in the cytoplasm of the infected cells, intensively. Conclusions The recombinant prokaryotic expression vector of DEV gI gene was constructed successfully. The gI protein was successfully expressed by E.coli BL21(DE3) and maintained its antigenicity very well. The basic information of the transcription and intracellular localization of gI gene were presented, that would be helpful to assess the possible role of DEV gI gene. The research will provide useful clues for further functional analysis of DEV gI gene. PMID:21595918

Two-Dimensional Electronic-Vibrational Spectroscopy of Chlorophyll a and b

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, Nicholas H. C.; Fleming, Graham R.

2016-03-03

Presented are two-dimensional electronic-vibrational (2DEV) spectra of isolated chlorophyll a and b in deuterated ethanol. We excite the Q-band electronic transitions and measure the effects on the carbonyl and C=C double-bond stretch region of the infrared spectrum. With the aid of density functional theory calculations, we provide assignments for the major features of the spectrum. We show how the 2DEV spectra can be used to readily distinguish different solvation states of the chlorophyll, with features corresponding to the minority pentacoordinate magnesium (Mg) species being resolved along each dimension of the 2DEV spectra from the dominant hexacoordinate Mg species. These assignmentsmore » represent a crucial first step toward the application of 2DEV spectroscopy to chlorophyll-containing pigment-protein complexes.« less

Activity Diagrams for DEVS Models: A Case Study Modeling Health Care Behavior

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ozmen, Ozgur; Nutaro, James J

Discrete Event Systems Specification (DEVS) is a widely used formalism for modeling and simulation of discrete and continuous systems. While DEVS provides a sound mathematical representation of discrete systems, its practical use can suffer when models become complex. Five main functions, which construct the core of atomic modules in DEVS, can realize the behaviors that modelers want to represent. The integration of these functions is handled by the simulation routine, however modelers can implement each function in various ways. Therefore, there is a need for graphical representations of complex models to simplify their implementation and facilitate their reproduction. In thismore » work, we illustrate the use of activity diagrams for this purpose in the context of a health care behavior model, which is developed with an agent-based modeling paradigm.« less

Dielectric elastomer vibrissal system for active tactile sensing

NASA Astrophysics Data System (ADS)

Conn, Andrew T.; Pearson, Martin J.; Pipe, Anthony G.; Welsby, Jason; Rossiter, Jonathan

2012-04-01

Rodents are able to dexterously navigate confined and unlit environments by extracting spatial and textural information with their whiskers (or vibrissae). Vibrissal-based active touch is suited to a variety of applications where vision is occluded, such as search-and-rescue operations in collapsed buildings. In this paper, a compact dielectric elastomer vibrissal system (DEVS) is described that mimics the vibrissal follicle-sinus complex (FSC) found in rodents. Like the vibrissal FSC, the DEVS encapsulates all sensitive mechanoreceptors at the root of a passive whisker within an antagonistic muscular system. Typically, rats actively whisk arrays of macro-vibrissae with amplitudes of up to +/-25°. It is demonstrated that these properties can be replicated by exploiting the characteristic large actuation strains and passive compliance of dielectric elastomers. A prototype DEVS is developed using VHB 4905 and embedded strain gauges bonded to the root of a tapered whisker. The DEVS is demonstrated to produce a maximum rotational output of +/-22.8°. An electro-mechanical model of the DEVS is derived, which incorporates a hyperelastic material model and Euler- Bernoulli beam equations. The model is shown to predict experimental measurements of whisking stroke amplitude and whisker deflection.

A Study to Identify the Transitional Training Needs for United States Army Medical Residents

DTIC Science & Technology

1988-07-29

34 workshops in the earlv 1970s, the issues cOn tinleld to have onlv ma rg ina l interests from teach ing inst itut ions for nearlv a decade. In 1982, the...Perspectives ( PRO VIEWS): These were presentations typically given by senior physicians who occupy positions of considerable administrative...n) JCAHO std day PRO -VIFW! %td dev I NE-VIEWS std dev qPAD-VIEWS std dev CAREI std oev Family Pract 27 3.4074 0 95 35769 I 12 36296 095 35185 1.03 3

Framework for automatic information extraction from research papers on nanocrystal devices.

PubMed

Dieb, Thaer M; Yoshioka, Masaharu; Hara, Shinjiro; Newton, Marcus C

2015-01-01

To support nanocrystal device development, we have been working on a computational framework to utilize information in research papers on nanocrystal devices. We developed an annotated corpus called " NaDev" (Nanocrystal Device Development) for this purpose. We also proposed an automatic information extraction system called "NaDevEx" (Nanocrystal Device Automatic Information Extraction Framework). NaDevEx aims at extracting information from research papers on nanocrystal devices using the NaDev corpus and machine-learning techniques. However, the characteristics of NaDevEx were not examined in detail. In this paper, we conduct system evaluation experiments for NaDevEx using the NaDev corpus. We discuss three main issues: system performance, compared with human annotators; the effect of paper type (synthesis or characterization) on system performance; and the effects of domain knowledge features (e.g., a chemical named entity recognition system and list of names of physical quantities) on system performance. We found that overall system performance was 89% in precision and 69% in recall. If we consider identification of terms that intersect with correct terms for the same information category as the correct identification, i.e., loose agreement (in many cases, we can find that appropriate head nouns such as temperature or pressure loosely match between two terms), the overall performance is 95% in precision and 74% in recall. The system performance is almost comparable with results of human annotators for information categories with rich domain knowledge information (source material). However, for other information categories, given the relatively large number of terms that exist only in one paper, recall of individual information categories is not high (39-73%); however, precision is better (75-97%). The average performance for synthesis papers is better than that for characterization papers because of the lack of training examples for characterization papers. Based on these results, we discuss future research plans for improving the performance of the system.

Theory of quantized systems: formal basis for DEVS/HLA distributed simulation environment

NASA Astrophysics Data System (ADS)

Zeigler, Bernard P.; Lee, J. S.

1998-08-01

In the context of a DARPA ASTT project, we are developing an HLA-compliant distributed simulation environment based on the DEVS formalism. This environment will provide a user- friendly, high-level tool-set for developing interoperable discrete and continuous simulation models. One application is the study of contract-based predictive filtering. This paper presents a new approach to predictive filtering based on a process called 'quantization' to reduce state update transmission. Quantization, which generates state updates only at quantum level crossings, abstracts a sender model into a DEVS representation. This affords an alternative, efficient approach to embedding continuous models within distributed discrete event simulations. Applications of quantization to message traffic reduction are discussed. The theory has been validated by DEVSJAVA simulations of test cases. It will be subject to further test in actual distributed simulations using the DEVS/HLA modeling and simulation environment.

In vivo evaluation of virtual electrode mapping and ablation utilizing a direct endocardial visualization ablation catheter.

PubMed

Chik, William W B; Barry, M A; Malchano, Zach; Wylie, Bryan; Pouliopoulos, Jim; Huang, Kaimin; Lu, Juntang; Thavapalachandran, Sujitha; Robinson, David; Saadat, Vahid; Thomas, Stuart P; Ross, David L; Kovoor, Pramesh; Thiagalingam, Aravinda

2012-01-01

Radiofrequency (RF) ablation utilizing direct endocardial visualization (DEV) requires a "virtual electrode" to deliver RF energy while preserving visualization. This study aimed to: (1) examine the virtual electrode RF ablation efficacy; (2) determine the optimal power and duration settings; and (3) evaluate the utility of virtual electrode unipolar electrograms. The DEV catheter lesions were compared to lesions formed using a 3.5 mm open irrigated tip catheter within the right atria of 12 sheep. Generator power settings for DEV were titrated from 12W, 14W and 16W for 20, 30 and 40 seconds duration with 25 mL/min saline irrigation. Standard irrigated tip catheter settings of 30W, 50°C for 30 seconds and 30 mL/min were used. The DEV lesions were significantly greater in surface area and both major and minor axes compared to irrigated tip lesions (surface area 19.43 ± 9.09 vs 10.88 ± 4.72 mm, P<0.01) with no difference in transmurality (93/94 vs 46/47) or depth (1.86 ± 0.75 vs 1.85 ± 0.57 mm). Absolute electrogram amplitude reduction was greater for DEV lesions (1.89 ± 1.31 vs 1.49 ± 0.78 mV, P = 0.04), but no difference in percentage reduction. Pre-ablation pacing thresholds were not different between DEV (0.79 ± 0.36 mA) and irrigated tip (0.73 ± 0.25 mA) lesions. There were no complications noted during ablation with either catheter. Virtual electrode ablation consistently created wider lesions at lower power compared to irrigated tip ablation. Virtual electrode electrograms showed a comparable pacing and sensing efficacy in detecting local myocardial electrophysiological changes. © 2011 Wiley Periodicals, Inc.

Soluble Factors Released by Endogenous Viable Cells Enhance the Antioxidant and Chemoattractive Activities of Cryopreserved Amniotic Membrane

PubMed Central

Duan-Arnold, Yi; Gyurdieva, Alexandra; Johnson, Amy; Jacobstein, Douglas A.; Danilkovitch, Alla

2015-01-01

Objective: Regulation of oxidative stress and recruitment of key cell types are activities of human amniotic membrane (hAM) that contribute to its benefits for wound treatment. Progress in tissue preservation has led to commercialization of hAM. The majority of hAM products are devitalized with various degrees of matrix alteration. Data show the importance of hAM matrix preservation, but little is known about the advantages of retaining viable endogenous cells. In this study, we compared the antioxidant and chemoattractive properties of viable intact cryopreserved hAM (int-hAM) and devitalized cryopreserved hAM (dev-hAM) to determine the benefits of cell preservation. Approach: We evaluated the ability of int-hAM and dev-hAM to protect fibroblasts from oxidant-induced cell damage, to suppress oxidants, and to recruit fibroblasts and keratinocytes in vitro. Results: Both the int-hAM–derived conditioned medium (CM) and the int-hAM tissue rescued significantly more fibroblasts from oxidant-induced damage than dev-hAM (844% and 93% more, respectively). The int-hAM CM showed a 202% greater antioxidant capacity than dev-hAM. The int-hAM CM enhanced the recruitment of fibroblasts and normal and diseased keratinocytes to a greater extent than dev-hAM (1,555%, 315%, and 151% greater, respectively). Innovation and Conclusion: Int-hAM, in which all native components are preserved, including endogenous viable cells, demonstrated a significantly greater antioxidant and fibroblast and keratinocyte chemoattractive potential compared to dev-hAM, in which viable cells are destroyed. The release of soluble factors that protect fibroblasts from oxidative injury by hAM containing viable cells is a mechanism of hAM antioxidant activity, which is a novel finding of this study. PMID:26029483

Resonance Energy Transfer-Based Molecular Switch Designed Using a Systematic Design Process Based on Monte Carlo Methods and Markov Chains

NASA Astrophysics Data System (ADS)

Rallapalli, Arjun

A RET network consists of a network of photo-active molecules called chromophores that can participate in inter-molecular energy transfer called resonance energy transfer (RET). RET networks are used in a variety of applications including cryptographic devices, storage systems, light harvesting complexes, biological sensors, and molecular rulers. In this dissertation, we focus on creating a RET device called closed-diffusive exciton valve (C-DEV) in which the input to output transfer function is controlled by an external energy source, similar to a semiconductor transistor like the MOSFET. Due to their biocompatibility, molecular devices like the C-DEVs can be used to introduce computing power in biological, organic, and aqueous environments such as living cells. Furthermore, the underlying physics in RET devices are stochastic in nature, making them suitable for stochastic computing in which true random distribution generation is critical. In order to determine a valid configuration of chromophores for the C-DEV, we developed a systematic process based on user-guided design space pruning techniques and built-in simulation tools. We show that our C-DEV is 15x better than C-DEVs designed using ad hoc methods that rely on limited data from prior experiments. We also show ways in which the C-DEV can be improved further and how different varieties of C-DEVs can be combined to form more complex logic circuits. Moreover, the systematic design process can be used to search for valid chromophore network configurations for a variety of RET applications. We also describe a feasibility study for a technique used to control the orientation of chromophores attached to DNA. Being able to control the orientation can expand the design space for RET networks because it provides another parameter to tune their collective behavior. While results showed limited control over orientation, the analysis required the development of a mathematical model that can be used to determine the distribution of dipoles in a given sample of chromophore constructs. The model can be used to evaluate the feasibility of other potential orientation control techniques.

Near-Earth Asteroid Prospector and the Commercial Development of Space Resources

NASA Astrophysics Data System (ADS)

Benson, Jim

1998-01-01

With the recent bad news that there may be little or no budget money for NASA to continue funding programs aimed at the human exploration of space beyond Earth's orbit, it becomes even more important for other initiatives to be considered. SpaceDev is the world' s first commercial space exploration company, and enjoys the strong support of Dan Goldin, Wes Huntress, Carl Pilcher, Alan Ladwig, and others at NASA headquarters. SpaceDev is also supported by such scientists as Jim Arnold, Paul Coleman, John Lewis, Steve Ostro, and many others. Taxpayers cannot be expected to carry the entire burden of exploration, construction, and settlement. The private sector must be involved, and the SpaceDev Near Earth Asteroid Prospector (NEAP) venture may provide a good example of how governments and the private sector can cooperate to accomplish these goals. SpaceDev believes that the utilization of in situ resources will take place on near-Earth asteroids before the Moon or Mars because many NEOs are energetically closer than the Moon or Mars and have a highly concentrated composition. SpaceDev currently expects to perform the following three missions: NEAP (science data gathering); NEAP 2, near-Earth asteroid or short-term comet sample return mission; and NEAP 3, in situ fuel production or resource extraction and utilization. These missions could pioneer the way for in situ resources for construction.

imDEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel

USDA-ARS?s Scientific Manuscript database

Interactive modules for data exploration and visualization (imDEV) is a Microsoft Excel spreadsheet embedded application providing an integrated environment for the analysis of omics data sets with a user-friendly interface. Individual modules were designed to provide toolsets to enable interactive ...

Information Ubiquity in Austere Locations

DTIC Science & Technology

2011-01-01

are incompatible (e.g., GSM vs. CDMA ), or are insecure for one’s purposes. There might be satellite communi- cations, but its access might be...Ave. Latency (Unloaded) Ave. Latency (Overloaded) Std Dev. (Unloaded) Std Dev. (Overloaded) M ill is ec on ds AOI UAV UAV 1 UAV 2 UAV 3 Joseph

Repair of Neocortex in a Model of Cortical Dysplasia

DTIC Science & Technology

2007-03-27

236. Dang L, Yoon K, Wang M, Gaiano N. 2006. Notch3 signaling promotes radial glial/progenitor character in the Mammalian telencephalon. Dev Neurosci...2006) Notch3 signaling promotes radial glial/progenitor character in the Mammalian telencephalon. Dev Neurosci 28:58- 69. Desai AR, McConnell SK (2000

Duck Enteritis Virus Glycoprotein D and B DNA Vaccines Induce Immune Responses and Immunoprotection in Pekin Ducks

PubMed Central

Zhao, Yan; Cao, Yongsheng; Cui, Lihong; Ma, Bo; Mu, Xiaoyu; Li, Yanwei; Zhang, Zhihui; Li, Dan; Wei, Wei; Gao, Mingchun; Wang, Junwei

2014-01-01

DNA vaccine is a promising strategy for protection against virus infection. However, little is known on the efficacy of vaccination with two plasmids for expressing the glycoprotein D (gD) and glycoprotein B (gB) of duck enteritis virus (DEV) in inducing immune response and immunoprotection against virulent virus infection in Pekin ducks. In this study, two eukaryotic expressing plasmids of pcDNA3.1-gB and pcDNA3.1-gD were constructed. Following transfection, the gB and gD expressions in DF1 cells were detected. Groups of ducks were vaccinated with pcDNA3.1-gB and/or pcDNA3.1-gD, and boosted with the same vaccine on day 14 post primary vaccination. We found that intramuscular vaccinations with pcDNA3.1-gB and/or pcDNA3.1-gD, but not control plasmid, stimulated a high frequency of CD4+ and CD8+ T cells in Pekin ducks, particularly with both plasmids. Similarly, vaccination with these plasmids, particularly with both plasmids, promoted higher levels of neutralization antibodies against DEV in Pekin ducks. More importantly, vaccination with both plasmids significantly reduced the virulent DEV-induced mortality in Pekin ducks. Our data indicated that vaccination with plasmids for expressing both gB and gD induced potent cellular and humoral immunity against DEV in Pekin ducks. Therefore, this vaccination strategy may be used for the prevention of DEV infection in Pekin ducks. PMID:24736466

Duck enteritis virus glycoprotein D and B DNA vaccines induce immune responses and immunoprotection in Pekin ducks.

PubMed

Zhao, Yan; Cao, Yongsheng; Cui, Lihong; Ma, Bo; Mu, Xiaoyu; Li, Yanwei; Zhang, Zhihui; Li, Dan; Wei, Wei; Gao, Mingchun; Wang, Junwei

2014-01-01

DNA vaccine is a promising strategy for protection against virus infection. However, little is known on the efficacy of vaccination with two plasmids for expressing the glycoprotein D (gD) and glycoprotein B (gB) of duck enteritis virus (DEV) in inducing immune response and immunoprotection against virulent virus infection in Pekin ducks. In this study, two eukaryotic expressing plasmids of pcDNA3.1-gB and pcDNA3.1-gD were constructed. Following transfection, the gB and gD expressions in DF1 cells were detected. Groups of ducks were vaccinated with pcDNA3.1-gB and/or pcDNA3.1-gD, and boosted with the same vaccine on day 14 post primary vaccination. We found that intramuscular vaccinations with pcDNA3.1-gB and/or pcDNA3.1-gD, but not control plasmid, stimulated a high frequency of CD4+ and CD8+ T cells in Pekin ducks, particularly with both plasmids. Similarly, vaccination with these plasmids, particularly with both plasmids, promoted higher levels of neutralization antibodies against DEV in Pekin ducks. More importantly, vaccination with both plasmids significantly reduced the virulent DEV-induced mortality in Pekin ducks. Our data indicated that vaccination with plasmids for expressing both gB and gD induced potent cellular and humoral immunity against DEV in Pekin ducks. Therefore, this vaccination strategy may be used for the prevention of DEV infection in Pekin ducks.

Framework for automatic information extraction from research papers on nanocrystal devices

PubMed Central

Yoshioka, Masaharu; Hara, Shinjiro; Newton, Marcus C

2015-01-01

Summary To support nanocrystal device development, we have been working on a computational framework to utilize information in research papers on nanocrystal devices. We developed an annotated corpus called “ NaDev” (Nanocrystal Device Development) for this purpose. We also proposed an automatic information extraction system called “NaDevEx” (Nanocrystal Device Automatic Information Extraction Framework). NaDevEx aims at extracting information from research papers on nanocrystal devices using the NaDev corpus and machine-learning techniques. However, the characteristics of NaDevEx were not examined in detail. In this paper, we conduct system evaluation experiments for NaDevEx using the NaDev corpus. We discuss three main issues: system performance, compared with human annotators; the effect of paper type (synthesis or characterization) on system performance; and the effects of domain knowledge features (e.g., a chemical named entity recognition system and list of names of physical quantities) on system performance. We found that overall system performance was 89% in precision and 69% in recall. If we consider identification of terms that intersect with correct terms for the same information category as the correct identification, i.e., loose agreement (in many cases, we can find that appropriate head nouns such as temperature or pressure loosely match between two terms), the overall performance is 95% in precision and 74% in recall. The system performance is almost comparable with results of human annotators for information categories with rich domain knowledge information (source material). However, for other information categories, given the relatively large number of terms that exist only in one paper, recall of individual information categories is not high (39–73%); however, precision is better (75–97%). The average performance for synthesis papers is better than that for characterization papers because of the lack of training examples for characterization papers. Based on these results, we discuss future research plans for improving the performance of the system. PMID:26665057

The Handbook of Medical Image Perception and Techniques

NASA Astrophysics Data System (ADS)

Samei, Ehsan; Krupinski, Elizabeth

2014-07-01

1. Medical image perception Ehsan Samei and Elizabeth Krupinski; Part I. Historical Reflections and Theoretical Foundations: 2. A short history of image perception in medical radiology Harold Kundel and Calvin Nodine; 3. Spatial vision research without noise Arthur Burgess; 4. Signal detection theory, a brief history Arthur Burgess; 5. Signal detection in radiology Arthur Burgess; 6. Lessons from dinners with the giants of modern image science Robert Wagner; Part II. Science of Image Perception: 7. Perceptual factors in reading medical images Elizabeth Krupinski; 8. Cognitive factors in reading medical images David Manning; 9. Satisfaction of search in traditional radiographic imaging Kevin Berbaum, Edmund Franken, Robert Caldwell and Kevin Schartz; 10. The role of expertise in radiologic image interpretation Calvin Nodine and Claudia Mello-Thoms; 11. A primer of image quality and its perceptual relevance Robert Saunders and Ehsan Samei; 12. Beyond the limitations of human vision Maria Petrou; Part III. Perception Metrology: 13. Logistical issues in designing perception experiments Ehsan Samei and Xiang Li; 14. ROC analysis: basic concepts and practical applications Georgia Tourassi; 15. Multi-reader ROC Steve Hillis; 16. Recent developments in FROC methodology Dev Chakraborty; 17. Observer models as a surrogate to perception experiments Craig Abbey and Miguel Eckstein; 18. Implementation of observer models Matthew Kupinski; Part IV. Decision Support and Computer Aided Detection: 19. CAD: an image perception perspective Maryellen Giger and Weijie Chen; 20. Common designs of CAD studies Yulei Jiang; 21. Perceptual effect of CAD in reading chest images Matthew Freedman and Teresa Osicka; 22. Perceptual issues in mammography and CAD Michael Ulissey; 23. How perceptual factors affect the use and accuracy of CAD for interpretation of CT images Ronald Summers; 24. CAD: risks and benefits for radiologists' decisions Eugenio Alberdi, Andrey Povyakalo, Lorenzo Strigini and Peter Ayton; Part V. Optimization and Practical Issues: 25. Optimization of 2D and 3D radiographic systems Jeff Siewerdson; 26. Applications of AFC methodology in optimization of CT imaging systems Kent Ogden and Walter Huda; 27. Perceptual issues in reading mammograms Margarita Zuley; 28. Perceptual optimization of display processing techniques Richard Van Metter; 29. Optimization of display systems Elizabeth Krupinski and Hans Roehrig; 30. Ergonomic radiologist workplaces in the PACS environment Carl Zylack; Part VI. Epilogue: 31. Future prospects of medical image perception Ehsan Samei and Elizabeth Krupinski; Index.

The Handbook of Medical Image Perception and Techniques

NASA Astrophysics Data System (ADS)

Samei, Ehsan; Krupinski, Elizabeth

2009-12-01

1. Medical image perception Ehsan Samei and Elizabeth Krupinski; Part I. Historical Reflections and Theoretical Foundations: 2. A short history of image perception in medical radiology Harold Kundel and Calvin Nodine; 3. Spatial vision research without noise Arthur Burgess; 4. Signal detection theory, a brief history Arthur Burgess; 5. Signal detection in radiology Arthur Burgess; 6. Lessons from dinners with the giants of modern image science Robert Wagner; Part II. Science of Image Perception: 7. Perceptual factors in reading medical images Elizabeth Krupinski; 8. Cognitive factors in reading medical images David Manning; 9. Satisfaction of search in traditional radiographic imaging Kevin Berbaum, Edmund Franken, Robert Caldwell and Kevin Schartz; 10. The role of expertise in radiologic image interpretation Calvin Nodine and Claudia Mello-Thoms; 11. A primer of image quality and its perceptual relevance Robert Saunders and Ehsan Samei; 12. Beyond the limitations of human vision Maria Petrou; Part III. Perception Metrology: 13. Logistical issues in designing perception experiments Ehsan Samei and Xiang Li; 14. ROC analysis: basic concepts and practical applications Georgia Tourassi; 15. Multi-reader ROC Steve Hillis; 16. Recent developments in FROC methodology Dev Chakraborty; 17. Observer models as a surrogate to perception experiments Craig Abbey and Miguel Eckstein; 18. Implementation of observer models Matthew Kupinski; Part IV. Decision Support and Computer Aided Detection: 19. CAD: an image perception perspective Maryellen Giger and Weijie Chen; 20. Common designs of CAD studies Yulei Jiang; 21. Perceptual effect of CAD in reading chest images Matthew Freedman and Teresa Osicka; 22. Perceptual issues in mammography and CAD Michael Ulissey; 23. How perceptual factors affect the use and accuracy of CAD for interpretation of CT images Ronald Summers; 24. CAD: risks and benefits for radiologists' decisions Eugenio Alberdi, Andrey Povyakalo, Lorenzo Strigini and Peter Ayton; Part V. Optimization and Practical Issues: 25. Optimization of 2D and 3D radiographic systems Jeff Siewerdson; 26. Applications of AFC methodology in optimization of CT imaging systems Kent Ogden and Walter Huda; 27. Perceptual issues in reading mammograms Margarita Zuley; 28. Perceptual optimization of display processing techniques Richard Van Metter; 29. Optimization of display systems Elizabeth Krupinski and Hans Roehrig; 30. Ergonomic radiologist workplaces in the PACS environment Carl Zylack; Part VI. Epilogue: 31. Future prospects of medical image perception Ehsan Samei and Elizabeth Krupinski; Index.

Brief Report: Insistence on Sameness, Anxiety, and Social Motivation in Children with Autism Spectrum Disorder

ERIC Educational Resources Information Center

Factor, Reina S.; Condy, Emma E.; Farley, Julee P.; Scarpa, Angela

2016-01-01

While the function of restricted repetitive behaviors (RRBs) in autism spectrum disorder (ASD) is unclear, RRBs may function as anxiety reduction strategies (Joosten et al. "J Autism Dev Disord" 39(3):521-531, 2009. Moreover, anxiety in ASD is associated with low social motivation (Swain et al. "J Autism Dev Disord," 2015. The…

Coxsackievirus B4 as a Causative Agent of Diabetes Mellitus Type 1: Is There a Role of Inefficiently Treated Drinking Water and Sewage in Virus Spreading?

PubMed

El-Senousy, Waled M; Abdel-Moneim, Adel; Abdel-Latif, Mahmoud; El-Hefnawy, Mohamed H; Khalil, Rehab G

2018-03-01

This study proposed to detect the enterovirus (EV) infection in children with type 1 diabetes mellitus (T1D) and to assess the role of insufficiently treated water and sewage as sources of viral spreading. Three hundred and eighty-two serum specimens of children with T1D, one hundred serum specimens of children who did not suffer from T1D as control, and forty-eight water and sewage samples were screened for EV RNA using nested RT-PCR. The number of genome copies and infectious units of EVs in raw and treated sewage and water samples were investigated using real-time (RT)-PCR and plaque assay, respectively. T1D markers [Fasting blood glucose (FBG), HbA1c, and C-peptide], in addition to anti-Coxsackie A & B viruses (CVs A & B) IgG, were measured in control, T1D-negative EV (T1D-EV - ), and T1D-positive EV (T1D-EV + ) children specimens. The prevalence of EV genome was significantly higher in diabetic children (26.2%, 100 out of 382) than the control children (0%, 0 out of 100). FBG and HbA1c in T1D-EV - and T1D-EV + children specimens were significantly higher than those in the control group, while c-peptide in T1D-EV - and T1D-EV + children specimens was significantly lower than that in the control (n = 100; p < 0.001). Positivity of anti-CVs A & B IgG was 70.7, 6.7, and 22.9% in T1D-EV + , T1D-EV - , and control children specimens, respectively. The prevalence of EV genome in drinking water and treated sewage samples was 25 and 33.3%, respectively. The prevalence of EV infectious units in drinking water and treated sewage samples was 8.5 and 25%, respectively. Quantification assays were performed to assess the capabilities of both wastewater treatment plants (WWTPs) and water treatment plants (WTPs) to remove EV. The reduction of EV genome in Zenin WWTP ranged from 2 to 4 log 10 , while the reduction of EV infectious units ranged from 1 to 4 log 10 . The reduction of EV genome in El-Giza WTP ranged from 1 to 3 log 10 , while the reduction of EV infectious units ranged from 1 to 2 log 10 . This capability of reduction did not prevent the appearance of infectious EV in treated sewage and drinking water. Plaque purification was performed for isolation of separate EV isolates from treated and untreated water and sewage samples. Characterization of the EV amplicons by RT-PCR followed by sequencing of these isolates revealed high homology (97%) with human coxsackievirus B4 (CV B4) in 60% of the isolates, while the rest of the isolates belonged to poliovirus type 1 and type 2 vaccine strains. On the other hand, characterization of the EV amplicons by RT-PCR followed by sequencing for T1D-EV + children specimens indicated that all samples contained CV B4 with the same sequence characterized in the environmental samples. CV B4-contaminated drinking water or treated sewage may play a role as a causative agent of T1D in children.

40 CFR Table F-3 to Subpart F of... - Critical Parameters of Idealized Ambient Particle Size Distributions

Code of Federal Regulations, 2010 CFR

2010-07-01

... Ambient Particle Size Distributions F Table F-3 to Subpart F of Part 53 Protection of Environment... Ambient Particle Size Distributions Idealized Distribution Fine Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) Coarse Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) PM2.5/PM10 Ratio FRM Sampler...

40 CFR Table F-3 to Subpart F of... - Critical Parameters of Idealized Ambient Particle Size Distributions

Code of Federal Regulations, 2013 CFR

2013-07-01

... Ambient Particle Size Distributions F Table F-3 to Subpart F of Part 53 Protection of Environment... Ambient Particle Size Distributions Idealized Distribution Fine Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m 3) Coarse Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m 3) PM 2.5/PM 10 Ratio FRM Sampler...

40 CFR Table F-3 to Subpart F of... - Critical Parameters of Idealized Ambient Particle Size Distributions

Code of Federal Regulations, 2012 CFR

2012-07-01

... Ambient Particle Size Distributions F Table F-3 to Subpart F of Part 53 Protection of Environment... Ambient Particle Size Distributions Idealized Distribution Fine Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) Coarse Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) PM2.5/PM10 Ratio FRM Sampler...

40 CFR Table F-3 to Subpart F of... - Critical Parameters of Idealized Ambient Particle Size Distributions

Code of Federal Regulations, 2011 CFR

2011-07-01

... Ambient Particle Size Distributions F Table F-3 to Subpart F of Part 53 Protection of Environment... Ambient Particle Size Distributions Idealized Distribution Fine Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) Coarse Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) PM2.5/PM10 Ratio FRM Sampler...

40 CFR Table F-3 to Subpart F of... - Critical Parameters of Idealized Ambient Particle Size Distributions

Code of Federal Regulations, 2014 CFR

2014-07-01

... Ambient Particle Size Distributions F Table F-3 to Subpart F of Part 53 Protection of Environment... Ambient Particle Size Distributions Idealized Distribution Fine Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) Coarse Particle Mode MMD (µm) Geo. Std. Dev. Conc. (µg/m3) PM 2.5/PM 10 Ratio FRM Sampler...

U.S. Air Force Enlisted Accessions: Upgrading the Pipeline

DTIC Science & Technology

2010-02-17

of State Boards of Education (NASBE) and the Association for Career and Technical Education (ACTE). Specific collaboration efforts include improving...Accessions Command and the Association for Career and Technical Education . November 20, 2009. http://dev.armyedspace.com/news-updates/news...Understanding Between the U.S. Army Accessions Command and the Association for Career and Technical Education . November 20, 2009. http://dev.armyedspace.com

SLAC Phone Directory: Search Form

Science.gov Websites

Facilities LCLS Hard X-Ray LCLS IT & Networking LCLS IT Photon Systems LCLS Instrumentation Dev LCLS Delivery Dept LCLS Science Research & DevDiv LCLS Soft X-Ray LCLS Technical Support LCLS User Beam Line Ops Sup SSRL MSD Hard X-rays SSRL MSD Soft X-rays SSRL MSDBeam Line Elec SSRL MSDBeam Line

Indispensable Amino Acid-Deficient Diets Induce Seizures in Ketogenic Diet-Fed Rodents, Demonstrating a Role for Amino Acid Balance in Dietary Treatments for Epilepsy.

PubMed

Gietzen, Dorothy W; Lindström, Sarah H; Sharp, James W; Teh, Pok Swee; Donovan, Michael J

2018-03-01

Low protein amounts are used in ketogenic diets (KDs), where an essential (indispensable) amino acid (IAA) can become limiting. Because the chemically sensitive, seizurogenic, anterior piriform cortex (APC) is excited by IAA limitation, an imbalanced KD could exacerbate seizure activity. We questioned whether dietary IAA depletion worsens seizure activity in rodents fed KDs. In a series of 6 trials, male rats or gerbils of both sexes (6-8/group) were given either control diets (CDs) appropriate for each trial, a KD, or a threonine-devoid (ThrDev) diet for ≥7 d, and tested for seizures using various stimuli. Microchip analysis of rat APCs was also used to determine if changes in transcripts for structures relevant to seizurogenesis are affected by a ThrDev diet. Glutamate release was measured in microdialysis samples from APCs during the first meal after 7 d on a CD or a ThrDev diet. Adult rats showed increased susceptibility to seizures in both chemical (58%) and electroshock (doubled) testing after 7 d on a ThrDev diet compared with CD (each trial, P ≤ 0.05). Seizure-prone Mongolian gerbils had fewer seizures after receiving a KD, but exacerbated seizures (68%) after 1 meal of KD minus Thr (KD-T compared with CD, P < 0.05). In kindled rats fed KD-T, both counts (19%) and severities (77%) of seizures were significantly elevated (KD-T compared with CD, P < 0.05). Gene transcript changes were consistent with enhanced seizure susceptibility (7-21 net-fold increases, P = 0.045-0.001) and glutamate release into the APC was increased acutely (4-fold at 20 min, 2.6-fold at 60 min, P < 0.05) after 7 d on a ThrDev diet. Seizure severity in rats and gerbils was reduced after KDs and exacerbated by ThrDev, both in KD- and CD-fed animals, consistent with the mechanistic studies. We suggest that a complete protein profile in KDs may improve IAA balance in the APC, thereby lowering the risk of seizures.

Observation of Electronic Excitation Transfer Through Light Harvesting Complex II Using Two-Dimensional Electronic-Vibrational Spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, Nicholas H. C.; Gruenke, Natalie L.; Oliver, Thomas A. A.

Light-harvesting complex II (LHCII) serves a central role in light harvesting for oxygenic photosynthesis and is arguably the most important photosynthetic antenna complex. In this article, we present two-dimensional electronic–vibrational (2DEV) spectra of LHCII isolated from spinach, demonstrating the possibility of using this technique to track the transfer of electronic excitation energy between specific pigments within the complex. We assign the spectral bands via comparison with the 2DEV spectra of the isolated chromophores, chlorophyll a and b, and present evidence that excitation energy between the pigments of the complex are observed in these spectra. Lastly, we analyze the essential componentsmore » of the 2DEV spectra using singular value decomposition, which makes it possible to reveal the relaxation pathways within this complex.« less

A Framework for Modeling and Simulation of the Artificial

DTIC Science & Technology

2012-01-01

y or n) >> y Name: petra Simple Aspects: face_shape/thin, nose/small, skintone/light, hair_color/black, hair_type/curly Integrated Aspects...Multiconference. Orlando, FL (2012) 23. Mittal, S., Risco- Martin , J.: Netcentric System of Systems Engineering with DEVS Unified Process. CRC Press (2012) 24...Mittal, S., Risco- Martin , J., Zeigler, B.: DEVS-based simulation web services for net-centric T&E. In: Proceedings of the 2007 summer computer

Naval Open Architecture Machinery Control Systems for Next Generation Integrated Power Systems

DTIC Science & Technology

2012-05-01

PORTABLE) OS / RTOS ADAPTATION MIDDLEWARE (FOR OS PORTABILITY) MACHINERY CONTROLLER FRAMEWORK MACHINERY CONTROL SYSTEM SERVICES POWER CONTROL SYSTEM...SERVICES SHIP SYSTEM SERVICES TTY 0 TTY N … OPERATING SYSTEM ( OS / RTOS ) COMPUTER HARDWARE UDP IP TCP RAW DEV 0 DEV N … POWER MANAGEMENT CONTROLLER...operating systems (DOS, Windows, Linux, OS /2, QNX, SCO Unix ...) COMPUTERS: ISA compatible motherboards, workstations and portables (Compaq, Dell

Tutorial for Thermophysics Universal Research Framework

DTIC Science & Technology

2017-07-30

DS1V are compared in Section 3.4.5. 3.4.2 Description of the Example Problem In a fluid, disturbance information is communicated within a medium at the...Universal Research Framework development (TURF-DEV) package on a case-by-case basis. Brief descriptions of the operations are provided in Tables 4.1 and...of additional experimental (E) and research (R) operations included in TURF-DEV. Module Operation Description DSMC SPDistDirectDSMCCellMergeOp (R

DEVS Unified Process for Web-Centric Development and Testing of System of Systems

DTIC Science & Technology

2008-05-20

gathering from the user. Further, methodologies have been developed to generate DEVS models from BPMN /BPEL-based and message-based requirement specifications...27] 3. BPMN /BPEL based system specifications: Business Process Modeling Notation ( BPMN ) [bpm] or Business Process Execution Language (BPEL) provide a...information is stored in .wsdl and .bpel files for BPEL but in proprietary format for BPMN . 4. DoDAF-based requirement specifications: Department of

Metabolic Regulation of Caspase 2 in Breast Cancer

DTIC Science & Technology

2011-04-01

S. The apoptosome: physiological, developmental, and pathological modes of regulation. Dev Cell 10, 549-61 ( 2006 ). 3. Baliga, B.C., Read, S.H...Mol Biol Cell 17, 2150-7 ( 2006 ). 9. Bergeron, L. et al. Defects in regulation of apoptosis in caspase-2-deficient mice. Genes Dev 12, 1304-14 (1998...Warburg, O. On the origin of cancer cells. Science 123, 309-14 (1956). 17. Lassus, P., Opitz- Araya , X. & Lazebnik, Y. Requirement for caspase-2 in

DDN (Defense Data Network) Protocol Handbook. Volume 3. Supplement

DTIC Science & Technology

1985-12-01

the physical configuration which results from this arrangement, Michael Padlipsky has described this as the " milking machine" approach to computer...NEIRJS-3 74 NETRJS-4 75 77 79 FINGER 81 HOSTS2-NS 83 MIT-ML-DEV 85 MIT-ML-DEV 87 89 SU-MIT-TG 91 MIT-DOV 93 DCP 95 SUPDUP 97 SWIFT- RVF ...PUP QUOTE RDP RJE RLP RTELNET RVD SAT-EXPAK SAT-MON SFTT? SMTP ST SU-MIT-TG SUNRPC SUPDUP SUR-MEAS SWIFT- RVF TACACS-DS TACNEWS

IEEE Std 730 Software Quality Assurance: Supporting CMMI-DEV v1.3, Product and Process Quality Assurance

DTIC Science & Technology

2011-05-27

frameworks 4 CMMI-DEV IEEE / ISO / IEC 15288 / 12207 Quality Assurance ©2011 Walz IEEE Life Cycle Processes & Artifacts • Systems Life Cycle Processes...TAG to ISO TC 176 Quality Management • Quality: ASQ, work experience • Software: three books, consulting, work experience • Systems: Telecom & DoD...and IEEE 730 SQA need to align. The P730 IEEE standards working group has expanded the scope of the SQA process standard to align with IS 12207

Genetic and Molecular Analysis of the Mechanisms by which TSC Regulates Neuronal Differentiation

DTIC Science & Technology

2009-03-01

2004 Programmed autophagy in the Drosophila fat body is in- duced by ecdysone through regulation of the PI3K pathway. Dev. Cell 7: 179–192. Sarbassov...embryonic Drosophila CNS. Mech. Dev. 64: 137–151. Scott, R. C., O. Schuldiner and T. P. Neufeld, 2004 Role and reg- ulation of starvation-induced autophagy ...in The Development of Drosophila melanogaster , edited by M. Bates and A. Martinez-Arias. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY

Friends, friendlessness, and the social consequences of gaining a theory of mind.

PubMed

Fink, Elian; Begeer, Sander; Peterson, Candida C; Slaughter, Virginia; de Rosnay, Marc

2015-03-01

Fink, Begeer, Peterson, Slaughter, and de Rosnay (2014) conducted a prospective longitudinal study showing that theory-of-mind (ToM) development at school entry (mean age 5.61 years) significantly predicted friendlessness both concurrently and 2 years later. Friendlessness (defined as lacking any friendship that is mutually reciprocated) is conceptually and empirically distinct from group popularity and independently predicts adverse mental health outcomes throughout life. Here, we respond to the thoughtful commentaries by Wellman (Brit. J. Dev. Psychol, 2015; 33, 24-26), Mizokawa and Koyasu (Brit. J. Dev. Psychol, 2015; 33, 21-23), and Lerner and Lillard (Brit. J. Dev. Psychol, 2015; 33, 18-20) with a focus on three key issues, namely (a) the definition and measurement of friendship, (b) the measurement of advanced ToM development beyond the preschool years, and (c) the exciting future potential for ToM-based training and intervention studies to combat chronic friendlessness. © 2015 The British Psychological Society.

A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma - A final report.

PubMed

Gnekow, Astrid K; Walker, David A; Kandels, Daniela; Picton, Susan; Giorgio Perilongo; Grill, Jacques; Stokland, Tore; Sandstrom, Per Eric; Warmuth-Metz, Monika; Pietsch, Torsten; Giangaspero, Felice; Schmidt, René; Faldum, Andreas; Kilmartin, Denise; De Paoli, Angela; De Salvo, Gian Luca

2017-08-01

The use of chemotherapy to manage newly diagnosed low grade glioma (LGG) was first introduced in the 1980s. One randomised trial has studied two- versus four-drug regimens with a duration of 12 months of treatment after resection. Within the European comprehensive treatment strategy for childhood LGG, the International Society of Paediatric Oncology-Low Grade Glioma (SIOP LGG) Committee launched a randomised trial involving 118 institutions and 11 countries to investigate the addition of etoposide (100 mg/m 2 , days 1, 2 & 3) to a four-course induction of vincristine (1.5 mg/m 2  × 10 wkly) and carboplatin (550 mg/m 2 q 3 weekly) as part of 18-month continuing treatment programme. Patients were recruited after imaging diagnosis, resection or biopsy with progressive disease/symptoms. Some 497 newly diagnosed patients (M/F 231/266; median age 4.26 years (interquartile range (IQR) 2.02-7.06)) were randomised to receive vincristine carboplatin (VC) (n = 249) or VC plus etoposide (VCE) during induction (n = 248), stratified by age and tumour site. No differences between the two arms were found in term of survival and radiological response. Response and non-progression rates at 24 weeks for VC and VCE, were 46% versus 41%, and 93% versus 91% respectively; 5-year Progression-Free Survival (PFS) and Overall Survival (OS) were 46% (StDev 3.5) versus 45% (StDev 3.5) and 89% (StDev 2.1) versus 89% (StDev 2.1) respectively. Age and diencephalic syndrome are adverse clinical risk factors for PFS and OS. 5-year OS for patients in early progression at week 24 were 46% (StDev 13.8) and 49% (StDev 16.5) in the two arms, respectively. The addition of etoposide to VC did not improve PFS or OS. High non-progression rates at 24 weeks justify retaining VC as standard first-line therapy. Infants with diencephalic syndrome and early progression need new treatments to be tested. Future trials should use neurological/visual and toxicity outcomes and be designed to discriminate between the impact on disease outcomes of 'duration of therapy' and 'age at stopping therapy'. Copyright © 2017. Published by Elsevier Ltd.

Supporting Data for FY 1990/1991 Biennial Budget: Budget Estimates Descriptive Summaries Submitted to Congress January 1989, Research, Development, Test & Evaluation, Navy

DTIC Science & Technology

1989-01-01

necessitate de -emphasizing network interface demonstrations in favor of real-time network interface technologies and slip ICEX demonstration of...Aperture Radar target classi- fication and Fault Diagnosis issues. o Demonstrate a complete, transportable , fully functional software engineering...BLK 3 MS 3B 109D MS 3A Blk 3 MS 2 TASM Milestones MS 3A 109D IOC Flex Upgrade MS 3B SW-3 MS 3B Blk 3 IOC Blk 3 Engineering Eng Dev Eng Dev DES Rev

CMMI (registered trademark) for Services (CMMI-SVC) Overview for Workshop

DTIC Science & Technology

2008-08-01

is from “DoD throws light on how it buys services [GCN 2006].” GAO data is from GAO report GAO-07-20. 5 CMMI for Services (CMMI-SVC) Forrester...Service Addition PAs 3 5 1 22 % of CMMI-DEV PAs are reused; % of Corporate Investments are potentially r usable! CMMI-DEV CMMI-ACQ CMMI-SVC 77...Service Modifications: •  21 amplification in 7 PAs •  5 added references •  1 modified PA (REQM) •  1 specific goal •  2 specific practices

Interim Radiological Scoping and Characterization Survey Report, 1963 Igloo 572 Accident (Former Medina Base), Lackland Training Annex, Lackland AFB, Texas

DTIC Science & Technology

2002-03-01

9045 4 8985 4 9001 5 8804 5 8893 Mean: 8788.8 Mean: 8925.4 Expected S.D.: 93.7 Expected S.D.: 94.5 Standard Dev.: 136.9 Standard Dev.: 107.4 Variance...subject to lit]) severe criminal penalties. Dissemination in 200204 5 042accordance with DoD Directive 5230.25" Air Force Institute for Environment...COVERED March 2002 INTERIM (2001 - 2002) 4. TITLE AND SUBTITLE 5 . FUNDING NUMBERS Interim Radiological Scoping and Characterization Survey Report, 1963

Experiences Supporting the Lunar Reconnaissance Orbiter Camera: the Devops Model

NASA Astrophysics Data System (ADS)

Licht, A.; Estes, N. M.; Bowman-Cisnesros, E.; Hanger, C. D.

2013-12-01

Introduction: The Lunar Reconnaissance Orbiter Camera (LROC) Science Operations Center (SOC) is responsible for instrument targeting, product processing, and archiving [1]. The LROC SOC maintains over 1,000,000 observations with over 300 TB of released data. Processing challenges compound with the acquisition of over 400 Gbits of observations daily creating the need for a robust, efficient, and reliable suite of specialized software. Development Environment: The LROC SOC's software development methodology has evolved over time. Today, the development team operates in close cooperation with the systems administration team in a model known in the IT industry as DevOps. The DevOps model enables a highly productive development environment that facilitates accomplishment of key goals within tight schedules[2]. The LROC SOC DevOps model incorporates industry best practices including prototyping, continuous integration, unit testing, code coverage analysis, version control, and utilizing existing open source software. Scientists and researchers at LROC often prototype algorithms and scripts in a high-level language such as MATLAB or IDL. After the prototype is functionally complete the solution is implemented as production ready software by the developers. Following this process ensures that all controls and requirements set by the LROC SOC DevOps team are met. The LROC SOC also strives to enhance the efficiency of the operations staff by way of weekly presentations and informal mentoring. Many small scripting tasks are assigned to the cognizant operations personnel (end users), allowing for the DevOps team to focus on more complex and mission critical tasks. In addition to leveraging open source software the LROC SOC has also contributed to the open source community by releasing Lunaserv [3]. Findings: The DevOps software model very efficiently provides smooth software releases and maintains team momentum. Scientists prototyping their work has proven to be very efficient as developers do not need to spend time iterating over small changes. Instead, these changes are realized in early prototypes and implemented before the task is seen by developers. The development practices followed by the LROC SOC DevOps team help facilitate a high level of software quality that is necessary for LROC SOC operations. Application to the Scientific Community: There is no replacement for having software developed by professional developers. While it is beneficial for scientists to write software, this activity should be seen as prototyping, which is then made production ready by professional developers. When constructed properly, even a small development team has the ability to increase the rate of software development for a research group while creating more efficient, reliable, and maintainable products. This strategy allows scientists to accomplish more, focusing on teamwork, rather than software development, which may not be their primary focus. 1. Robinson et al. (2010) Space Sci. Rev. 150, 81-124 2. DeGrandis. (2011) Cutter IT Journal. Vol 24, No. 8, 34-39 3. Estes, N.M.; Hanger, C.D.; Licht, A.A.; Bowman-Cisneros, E.; Lunaserv Web Map Service: History, Implementation Details, Development, and Uses, http://adsabs.harvard.edu/abs/2013LPICo1719.2609E.

Turbulence and fire-spotting effects into wild-land fire simulators

NASA Astrophysics Data System (ADS)

Kaur, Inderpreet; Mentrelli, Andrea; Bosseur, Frédéric; Filippi, Jean-Baptiste; Pagnini, Gianni

2016-10-01

This paper presents a mathematical approach to model the effects and the role of phenomena with random nature such as turbulence and fire-spotting into the existing wildfire simulators. The formulation proposes that the propagation of the fire-front is the sum of a drifting component (obtained from an existing wildfire simulator without turbulence and fire-spotting) and a random fluctuating component. The modelling of the random effects is embodied in a probability density function accounting for the fluctuations around the fire perimeter which is given by the drifting component. In past, this formulation has been applied to include these random effects into a wildfire simulator based on an Eulerian moving interface method, namely the Level Set Method (LSM), but in this paper the same formulation is adapted for a wildfire simulator based on a Lagrangian front tracking technique, namely the Discrete Event System Specification (DEVS). The main highlight of the present study is the comparison of the performance of a Lagrangian and an Eulerian moving interface method when applied to wild-land fire propagation. Simple idealised numerical experiments are used to investigate the potential applicability of the proposed formulation to DEVS and to compare its behaviour with respect to the LSM. The results show that DEVS based wildfire propagation model qualitatively improves its performance (e.g., reproducing flank and back fire, increase in fire spread due to pre-heating of the fuel by hot air and firebrands, fire propagation across no fuel zones, secondary fire generation, ...) when random effects are included according to the present formulation. The performance of DEVS and LSM based wildfire models is comparable and the only differences which arise among the two are due to the differences in the geometrical construction of the direction of propagation. Though the results presented here are devoid of any validation exercise and provide only a proof of concept, they show a strong inclination towards an intended operational use. The existing LSM or DEVS based operational simulators like WRF-SFIRE and ForeFire respectively can serve as an ideal basis for the same.

Evaluating metrics of local topographic position for multiscale geomorphometric analysis

NASA Astrophysics Data System (ADS)

Newman, D. R.; Lindsay, J. B.; Cockburn, J. M. H.

2018-07-01

The field of geomorphometry has increasingly moved towards the use of multiscale analytical techniques, due to the availability of fine-resolution digital elevation models (DEMs) and the inherent scale-dependency of many DEM-derived attributes such as local topographic position (LTP). LTP is useful for landform and soils mapping and numerous other environmental applications. Multiple LTP metrics have been proposed and applied in the literature; however, elevation percentile (EP) is notable for its robustness to elevation error and applicability to non-Gaussian local elevation distributions, both of which are common characteristics of DEM data sets. Multiscale LTP analysis involves the estimation of spatial patterns using a range of neighborhood sizes, traditionally achieved by applying spatial filtering techniques with varying kernel sizes. While EP can be demonstrated to provide accurate estimates of LTP, the computationally intensive method of its calculation makes it unsuited to multiscale LTP analysis, particularly at large neighborhood sizes or with fine-resolution DEMs. This research assessed the suitability of three LTP metrics for multiscale terrain characterization by quantifying their computational efficiency and by comparing their ability to approximate EP spatial patterns under varying topographic conditions. The tested LTP metrics included: deviation from mean elevation (DEV), percent elevation range (PER), and the novel relative topographic position (RTP) index. The results demonstrated that DEV, calculated using the integral image technique, offers fast and scale-invariant computation. DEV spatial patterns were strongly correlated with EP (r2 range of 0.699 to 0.967) under all tested topographic conditions. RTP was also a strong predictor of EP (r2 range of 0.594 to 0.917). PER was the weakest predictor of EP (r2 range of 0.031 to 0.801) without offering a substantial improvement in computational efficiency over RTP. PER was therefore determined to be unsuitable for most multiscale applications. It was concluded that the scale-invariant property offered by the integral image used by the DEV method counters the minor losses in robustness compared to EP, making DEV the optimal LTP metric for multiscale applications.

Differences between individual and societal health state valuations: any link with personality?

PubMed

Chapman, Benjamin P; Franks, Peter; Duberstein, Paul R; Jerant, Anthony

2009-08-01

The concept of "adaptation" has been proposed to account for differences between individual and societal valuations of specific health states in patients with chronic diseases. Little is known about psychological indices of adaptational capacity, which may predict differences in individual and societal valuations of health states. We investigated whether such differences were partially explained by personality traits in chronic disease patients. Analysis of baseline data of randomized controlled trial. Three hundred seventy patients with chronic disease. The NEO-five factor inventory measure of personality, EuroQoL-5D (EQ-5D) societal-based, and the EQ visual analogue scale individually-based measures of health valuation. Regression analyses modeled Dev, a measure of difference between the EQ-Visual Analogue Scale and EQ-5D, as a function of personality traits, sociodemographic factors, and chronic diseases. Individual valuations were significantly and clinically higher than societal valuations among patients in the second and third quartile of conscientiousness (Dev = 0.08, P = 0.01); among covariates, only depression (Dev = -0.04, P = 0.046) was also associated with Dev. Compared with societal valuations of a given health state, persons at higher quartiles of conscientiousness report less disutility associated with poor health. The effect is roughly twice that of some estimates of minimally important clinical differences on the EQ-5D and of depression. Although useful at the aggregate level, societal preference measures may systematically undervalue the health states of more conscientious individuals. Future work should examine the impact this has on individual patient outcome evaluation in clinical studies.

Differences Between Individual and Societal Health State Valuations

PubMed Central

Chapman, Benjamin P.; Franks, Peter; Duberstein, Paul R.; Jerant, Anthony

2009-01-01

Objective The concept of “adaptation” has been proposed to account for differences between individual and societal valuations of specific health states in patients with chronic diseases. Little is known about psychological indices of adaptational capacity, which may predict differences in individual and societal valuations of health states. We investigated whether such differences were partially explained by personality traits in chronic disease patients. Research Design Analysis of baseline data of randomized controlled trial. Subjects Three hundred seventy patients with chronic disease. Measures The NEO-five factor inventory measure of personality, EuroQoL-5D (EQ-5D) societal-based, and the EQ visual analogue scale individually-based measures of health valuation. Results Regression analyses modeled Dev, a measure of difference between the EQ-Visual Analogue Scale and EQ-5D, as a function of personality traits, sociodemographic factors, and chronic diseases. Individual valuations were significantly and clinically higher than societal valuations among patients in the second and third quartile of conscientiousness (Dev = 0.08, P = 0.01); among covariates, only depression (Dev = -0.04, P = 0.046) was also associated with Dev. Conclusion Compared with societal valuations of a given health state, persons at higher quartiles of conscientiousness report less disutility associated with poor health. The effect is roughly twice that of some estimates of minimally important clinical differences on the EQ-5D and of depression. Although useful at the aggregate level, societal preference measures may systematically undervalue the health states of more conscientious individuals. Future work should examine the impact this has on individual patient outcome evaluation in clinical studies. PMID:19543121

The Northern Circumpolar Soil Carbon Database: spatially distributed datasets of soil coverage and soil carbon storage in the northern permafrost regions

NASA Astrophysics Data System (ADS)

Hugelius, G.; Tarnocai, C.; Broll, G.; Canadell, J. G.; Kuhry, P.; Swanson, D. K.

2012-08-01

High latitude terrestrial ecosystems are key components in the global carbon (C) cycle. Estimates of global soil organic carbon (SOC), however, do not include updated estimates of SOC storage in permafrost-affected soils or representation of the unique pedogenic processes that affect these soils. The Northern Circumpolar Soil Carbon Database (NCSCD) was developed to quantify the SOC stocks in the circumpolar permafrost region (18.7 × 106 km2). The NCSCD is a polygon-based digital database compiled from harmonized regional soil classification maps in which data on soil order coverage has been linked to pedon data (n = 1647) from the northern permafrost regions to calculate SOC content and mass. In addition, new gridded datasets at different spatial resolutions have been generated to facilitate research applications using the NCSCD (standard raster formats for use in Geographic Information Systems and Network Common Data Form files common for applications in numerical models). This paper describes the compilation of the NCSCD spatial framework, the soil sampling and soil analyses procedures used to derive SOC content in pedons from North America and Eurasia and the formatting of the digital files that are available online. The potential applications and limitations of the NCSCD in spatial analyses are also discussed. The database has the doi:10.5879/ecds/00000001. An open access data-portal with all the described GIS-datasets is available online at: http://dev1.geo.su.se/bbcc/dev/ncscd/.

Oscillatory support for rapid frequency change processing in infants.

PubMed

Musacchia, Gabriella; Choudhury, Naseem A; Ortiz-Mantilla, Silvia; Realpe-Bonilla, Teresa; Roesler, Cynthia P; Benasich, April A

2013-11-01

Rapid auditory processing and auditory change detection abilities are crucial aspects of speech and language development, particularly in the first year of life. Animal models and adult studies suggest that oscillatory synchrony, and in particular low-frequency oscillations play key roles in this process. We hypothesize that infant perception of rapid pitch and timing changes is mediated, at least in part, by oscillatory mechanisms. Using event-related potentials (ERPs), source localization and time-frequency analysis of event-related oscillations (EROs), we examined the neural substrates of rapid auditory processing in 4-month-olds. During a standard oddball paradigm, infants listened to tone pairs with invariant standard (STD, 800-800 Hz) and variant deviant (DEV, 800-1200 Hz) pitch. STD and DEV tone pairs were first presented in a block with a short inter-stimulus interval (ISI) (Rapid Rate: 70 ms ISI), followed by a block of stimuli with a longer ISI (Control Rate: 300 ms ISI). Results showed greater ERP peak amplitude in response to the DEV tone in both conditions and later and larger peaks during Rapid Rate presentation, compared to the Control condition. Sources of neural activity, localized to right and left auditory regions, showed larger and faster activation in the right hemisphere for both rate conditions. Time-frequency analysis of the source activity revealed clusters of theta band enhancement to the DEV tone in right auditory cortex for both conditions. Left auditory activity was enhanced only during Rapid Rate presentation. These data suggest that local low-frequency oscillatory synchrony underlies rapid processing and can robustly index auditory perception in young infants. Furthermore, left hemisphere recruitment during rapid frequency change discrimination suggests a difference in the spectral and temporal resolution of right and left hemispheres at a very young age. © 2013 Elsevier Ltd. All rights reserved.

A method for the direct measurement of electronic site populations in a molecular aggregate using two-dimensional electronic-vibrational spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, Nicholas H. C.; Dong, Hui; Oliver, Thomas A. A.

2015-09-28

Two dimensional electronic spectroscopy has proven to be a valuable experimental technique to reveal electronic excitation dynamics in photosynthetic pigment-protein complexes, nanoscale semiconductors, organic photovoltaic materials, and many other types of systems. It does not, however, provide direct information concerning the spatial structure and dynamics of excitons. 2D infrared spectroscopy has become a widely used tool for studying structural dynamics but is incapable of directly providing information concerning electronic excited states. 2D electronic-vibrational (2DEV) spectroscopy provides a link between these domains, directly connecting the electronic excitation with the vibrational structure of the system under study. In this work, we derivemore » response functions for the 2DEV spectrum of a molecular dimer and propose a method by which 2DEV spectra could be used to directly measure the electronic site populations as a function of time following the initial electronic excitation. We present results from the response function simulations which show that our proposed approach is substantially valid. This method provides, to our knowledge, the first direct experimental method for measuring the electronic excited state dynamics in the spatial domain, on the molecular scale.« less

A method for the direct measurement of electronic site populations in a molecular aggregate using two-dimensional electronic-vibrational spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, Nicholas H. C.; Dong, Hui; Oliver, Thomas A. A.

2015-09-28

Two dimensional electronic spectroscopy has proved to be a valuable experimental technique to reveal electronic excitation dynamics in photosynthetic pigment-protein complexes, nanoscale semiconductors, organic photovoltaic materials, and many other types of systems. It does not, however, provide direct information concerning the spatial structure and dynamics of excitons. 2D infrared spectroscopy has become a widely used tool for studying structural dynamics but is incapable of directly providing information concerning electronic excited states. 2D electronic-vibrational (2DEV) spectroscopy provides a link between these domains, directly connecting the electronic excitation with the vibrational structure of the system under study. In this work, we derivemore » response functions for the 2DEV spectrum of a molecular dimer and propose a method by which 2DEV spectra could be used to directly measure the electronic site populations as a function of time following the initial electronic excitation. We present results from the response function simulations which show that our proposed approach is substantially valid. This method provides, to our knowledge, the first direct experimental method for measuring the electronic excited state dynamics in the spatial domain, on the molecular scale.« less

A method for the direct measurement of electronic site populations in a molecular aggregate using two-dimensional electronic-vibrational spectroscopy.

PubMed

Lewis, Nicholas H C; Dong, Hui; Oliver, Thomas A A; Fleming, Graham R

2015-09-28

Two dimensional electronic spectroscopy has proved to be a valuable experimental technique to reveal electronic excitation dynamics in photosynthetic pigment-protein complexes, nanoscale semiconductors, organic photovoltaic materials, and many other types of systems. It does not, however, provide direct information concerning the spatial structure and dynamics of excitons. 2D infrared spectroscopy has become a widely used tool for studying structural dynamics but is incapable of directly providing information concerning electronic excited states. 2D electronic-vibrational (2DEV) spectroscopy provides a link between these domains, directly connecting the electronic excitation with the vibrational structure of the system under study. In this work, we derive response functions for the 2DEV spectrum of a molecular dimer and propose a method by which 2DEV spectra could be used to directly measure the electronic site populations as a function of time following the initial electronic excitation. We present results from the response function simulations which show that our proposed approach is substantially valid. This method provides, to our knowledge, the first direct experimental method for measuring the electronic excited state dynamics in the spatial domain, on the molecular scale.

A novel measure of ewe efficiency for breeding and benchmarking purposes.

PubMed

McHugh, Nóirín; Pabiou, Thierry; McDermott, Kevin; Wall, Eamon; Berry, Donagh P

2018-06-04

Ewe efficiency has traditionally been defined as the ratio of litter weight to ewe weight; given the statistical properties of ratio traits, an alternative strategy is proposed in the present study. The concept of using the deviation in performance of an animal from the population norm has grown in popularity as a measure of animal-level efficiency. The objective of the present study was to define novel measures of efficiency for sheep, which considers the combined weight of a litter of lambs relative to the weight of their dam, and vice versa. Two novel traits, representing the deviation in total litter weight at 40 d (DEV40L) or weaning (DEVweanL), were calculated as the residuals of a statistical model, with litter weight as the dependent variable and with the fixed effects of litter rearing size, contemporary group, and ewe weight. The deviation in ewe weight at 40-d postlambing (DEV40E) or weaning (DEVweanE) was derived using a similar approach but with ewe weight and litter weight interchanged as the dependent variable. Variance components for each trait were estimated by first deriving the litter or ewe weight deviation phenotype and subsequently estimating the variance components. The phenotypic SD in DEV40L and DEVweanL was 8.46 and 15.37 kg, respectively; the mean litter weight at 40 d and weaning was 30.97 and 47.68 kg, respectively. The genetic SD and heritability for DEV40L was 2.65 kg and 0.12, respectively. For DEVweanL, the genetic SD and heritability was 4.94 kg and 0.13, respectively. The average ewe weight at 40-d postlambing and at weaning was 66.43 and 66.87 kg, respectively. The genetic SD and heritability for DEV40E was 4.33 kg and 0.24, respectively. The heritability estimated for DEVweanE was 0.31. The traits derived in the present study may be useful not only for phenotypic benchmarking of ewes within flock on performance but also for benchmarking flocks against each other; furthermore, the extent of genetic variability in all traits, coupled with the fact that the data required to generate these novel phenotypes are usually readily available, signals huge potential within sheep breeding programs.

Modeling magnetic fields from a DC power cable buried beneath San Francisco Bay based on empirical measurements

DOE PAGES

Kavet, Robert; Wyman, Megan T.; Klimley, A. Peter; ...

2016-02-25

Here, the Trans Bay Cable (TBC) is a ±200-kilovolt (kV), 400 MW 85-km long High Voltage Direct Current (DC) buried transmission line linking Pittsburg, CA with San Francisco, CA (SF) beneath the San Francisco Estuary. The TBC runs parallel to the migratory route of various marine species, including green sturgeon, Chinook salmon, and steelhead trout. In July and August 2014, an extensive series of magnetic field measurements were taken using a pair of submerged Geometrics magnetometers towed behind a survey vessel in four locations in the San Francisco estuary along profiles that cross the cable’s path; these included the Sanmore » Francisco-Oakland Bay Bridge (BB), the Richmond-San Rafael Bridge (RSR), the Benicia- Martinez Bridge (Ben) and an area in San Pablo Bay (SP) in which a bridge is not present. In this paper, we apply basic formulas that ideally describe the magnetic field from a DC cable summed vectorially with the background geomagnetic field (in the absence of other sources that would perturb the ambient field) to derive characteristics of the cable that are otherwise not immediately observable. Magnetic field profiles from measurements taken along 170 survey lines were inspected visually for evidence of a distinct pattern representing the presence of the cable. Many profiles were dominated by field distortions unrelated to the cable caused by bridge structures or other submerged objects, and the cable’s contribution to the field was not detectable. BB, with 40 of the survey lines, did not yield usable data for these reasons. The unrelated anomalies could be up to 100 times greater than those from the cable. In total, discernible magnetic field profiles measured from 76 survey lines were regressed against the equations, representing eight days of measurement. The modeled field anomalies due to the cable (the difference between the maximum and minimum field along the survey line at the cable crossing) were virtually identical to the measured values. The modeling yielded a pooled cable depth below the bay floor of 2.06 m (±1.46 std dev), and estimated the angle to the horizontal of the imaginary line connecting the crosssectional center of the cable’s two conductors (0.1143 m apart) as 178.9° ±61.9° (std dev) for Ben, 78.6°±37.0° (std dev) for RSR, and 139.9°±27.4° (std dev) for SP. The mean of the eight daily average currents derived from the regressions was 986 ±185 amperes (A) (std dev), as compared to 722 ±95 A (std dev) provided by Trans Bay Cable LLC. Overall, the regressions based on fundamental principles (Biot Savart law) and the vectorial summation of cable and geomagnetic fields provide estimates of cable characteristics consistent with plausible expectations.« less

Modeling magnetic fields from a DC power cable buried beneath San Francisco Bay based on empirical measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kavet, Robert; Wyman, Megan T.; Klimley, A. Peter

Here, the Trans Bay Cable (TBC) is a ±200-kilovolt (kV), 400 MW 85-km long High Voltage Direct Current (DC) buried transmission line linking Pittsburg, CA with San Francisco, CA (SF) beneath the San Francisco Estuary. The TBC runs parallel to the migratory route of various marine species, including green sturgeon, Chinook salmon, and steelhead trout. In July and August 2014, an extensive series of magnetic field measurements were taken using a pair of submerged Geometrics magnetometers towed behind a survey vessel in four locations in the San Francisco estuary along profiles that cross the cable’s path; these included the Sanmore » Francisco-Oakland Bay Bridge (BB), the Richmond-San Rafael Bridge (RSR), the Benicia- Martinez Bridge (Ben) and an area in San Pablo Bay (SP) in which a bridge is not present. In this paper, we apply basic formulas that ideally describe the magnetic field from a DC cable summed vectorially with the background geomagnetic field (in the absence of other sources that would perturb the ambient field) to derive characteristics of the cable that are otherwise not immediately observable. Magnetic field profiles from measurements taken along 170 survey lines were inspected visually for evidence of a distinct pattern representing the presence of the cable. Many profiles were dominated by field distortions unrelated to the cable caused by bridge structures or other submerged objects, and the cable’s contribution to the field was not detectable. BB, with 40 of the survey lines, did not yield usable data for these reasons. The unrelated anomalies could be up to 100 times greater than those from the cable. In total, discernible magnetic field profiles measured from 76 survey lines were regressed against the equations, representing eight days of measurement. The modeled field anomalies due to the cable (the difference between the maximum and minimum field along the survey line at the cable crossing) were virtually identical to the measured values. The modeling yielded a pooled cable depth below the bay floor of 2.06 m (±1.46 std dev), and estimated the angle to the horizontal of the imaginary line connecting the crosssectional center of the cable’s two conductors (0.1143 m apart) as 178.9° ±61.9° (std dev) for Ben, 78.6°±37.0° (std dev) for RSR, and 139.9°±27.4° (std dev) for SP. The mean of the eight daily average currents derived from the regressions was 986 ±185 amperes (A) (std dev), as compared to 722 ±95 A (std dev) provided by Trans Bay Cable LLC. Overall, the regressions based on fundamental principles (Biot Savart law) and the vectorial summation of cable and geomagnetic fields provide estimates of cable characteristics consistent with plausible expectations.« less

Quantitative diagnostic method for biceps long head tendinitis by using ultrasound.

PubMed

Huang, Shih-Wei; Wang, Wei-Te

2013-01-01

To investigate the feasibility of grayscale quantitative diagnostic method for biceps tendinitis and determine the cut-off points of a quantitative biceps ultrasound (US) method to diagnose biceps tendinitis. Design. Prospective cross-sectional case controlled study. Outpatient rehabilitation service. A total of 336 shoulder pain patients with suspected biceps tendinitis were recruited in this prospective observational study. The grayscale pixel data of the range of interest (ROI) were obtained for both the transverse and longitudinal views of the biceps US. A total of 136 patients were classified with biceps tendinitis, and 200 patients were classified as not having biceps tendinitis based on the diagnostic criteria. Based on the Youden index, the cut-off points were determined as 26.85 for the transverse view and 21.25 for the longitudinal view of the standard deviation (StdDev) of the ROI values, respectively. When the ROI evaluation of the US surpassed the cut-off point, the sensitivity was 68% and the specificity was 90% in the StdDev of the transverse view, and the sensitivity was 81% and the specificity was 73% in the StdDev of the longitudinal view to diagnose biceps tendinitis. For equivocal cases or inexperienced sonographers, our study provides a more objective method for diagnosing biceps tendinitis in shoulder pain patients.

Prevalence, sources, and predictors of soy consumption in breast cancer

PubMed Central

Lammersfeld, Carolyn A; King, Jessica; Walker, Sharon; Vashi, Pankaj G; Grutsch, James F; Lis, Christopher G; Gupta, Digant

2009-01-01

Background A number of components in soy appear to have anticancer properties, including the isoflavones, genistein and daidzein. The use of soy by women with breast cancer is now being questioned because of the estrogen-like effects of isoflavones and possible interactions with tamoxifen. Clinicians providing nutrition counseling to these women are concerned because the availability of soy foods has increased dramatically in the past few years. The goal of this study was to quantify the intake of isoflavones in women with breast cancer. Methods A cross-sectional study of 100 women with breast cancer treated at Cancer Treatment Centers of America® between 09/03 and 02/04. Each patient completed a soy food frequency questionnaire (FFQ) that was scored by Fred Hutchinson Cancer Research Center. Demographic and clinical predictors of soy intake were evaluated using one-way non-parametric Mann Whitney test and non-parametric spearman's rank correlation. Results Mean age was 50.5 years (std. dev. = 9.4; range 31–70) and mean BMI was 27.3 kg/m2 (std. dev. = 6.75; range 17–59). Genistein and Daidzein consumption was limited to 65 patients with a mean intake of 11.6 mg/day (std. dev. = 21.9; range 0–97.4) and 7.6 mg/day (std. dev. = 14.1; range 0–68.9) respectively. Soy milk (37%) and pills containing soy, isoflavones, or "natural" estrogen (24%) were the two biggest contributors to isoflavone intake. Conclusion Our study suggests that the isoflavone intake of breast cancer patients at our hospital was quite variable. Thirty-five patients reported no soy intake. The mean daily intake of 11.6 mg genistein and 7.4 mg daidzein, is the equivalent of less than 1/4 cup of tofu per day. This amount is higher than what has been previously reported in non-Asian American women. PMID:19159489

Analysing inter-relationships among water, governance, human development variables in developing countries: WatSan4Dev database coherency analysis

NASA Astrophysics Data System (ADS)

Dondeynaz, C.; Carmona Moreno, C.; Céspedes Lorente, J. J.

2012-01-01

The "Integrated Water Resources Management" principle was formally laid down at the International Conference on Water and Sustainable development in Dublin 1992. One of the main results of this conference is that improving Water and Sanitation Services (WSS), being a complex and interdisciplinary issue, passes through collaboration and coordination of different sectors (environment, health, economic activities, governance, and international cooperation). These sectors influence or are influenced by the access to WSS. The understanding of these interrelations appears as crucial for decision makers in the water sector. In this framework, the Joint Research Centre (JRC) of the European Commission (EC) has developed a new database (WatSan4Dev database) containing 45 indicators (called variables in this paper) from environmental, socio-economic, governance and financial aid flows data in developing countries. This paper describes the development of the WatSan4Dev dataset, the statistical processes needed to improve the data quality; and, finally, the analysis to verify the database coherence is presented. At the light of the first analysis, WatSan4Dev Dataset shows the coherency among the different variables that are confirmed by the direct field experience and/or the scientific literature in the domain. Preliminary analysis of the relationships indicates that the informal urbanisation development is an important factor influencing negatively the percentage of the population having access to WSS. Health, and in particular children health, benefits from the improvement of WSS. Efficient environmental governance is also an important factor for providing improved water supply services. The database would be at the base of posterior analyses to better understand the interrelationships between the different indicators associated in the water sector in developing countries. A data model using the different indicators will be realised on the next phase of this research work.

Identification of a spliced gene from duck enteritis virus encoding a protein homologous to UL15 of herpes simplex virus 1.

PubMed

Zhu, Hongwei; Li, Huixin; Han, Zongxi; Shao, Yuhao; Wang, Yu; Kong, Xiangang

2011-04-06

In herpesviruses, UL15 homologue is a subunit of terminase complex responsible for cleavage and packaging of the viral genome into pre-assembled capsids. However, for duck enteritis virus (DEV), the causative agent of duck viral enteritis (DVE), the genomic sequence was not completely determined until most recently. There is limited information of this putative spliced gene and its encoding protein. DEV UL15 consists of two exons with a 3.5 kilobases (kb) inron and transcribes into two transcripts: the full-length UL15 and an N-terminally truncated UL15.5. The 2.9 kb UL15 transcript encodes a protein of 739 amino acids with an approximate molecular mass of 82 kiloDaltons (kDa), whereas the UL15.5 transcript is 1.3 kb in length, containing a putative 888 base pairs (bp) ORF that encodes a 32 kDa product. We also demonstrated that UL15 gene belonged to the late kinetic class as its expression was sensitive to cycloheximide and phosphonoacetic acid. UL15 is highly conserved within the Herpesviridae, and contains Walker A and B motifs homologous to the catalytic subunit of the bacteriophage terminase as revealed by sequence analysis. Phylogenetic tree constructed with the amino acid sequences of 23 herpesvirus UL15 homologues suggests a close relationship of DEV to the Mardivirus genus within the Alphaherpesvirinae. Further, the UL15 and UL15.5 proteins can be detected in the infected cell lysate but not in the sucrose density gradient-purified virion when reacting with the antiserum against UL15. Within the CEF cells, the UL15 and/or UL15.5 localize(s) in the cytoplasm at 6 h post infection (h p. i.) and mainly in the nucleus at 12 h p. i. and at 24 h p. i., while accumulate(s) in the cytoplasm in the absence of any other viral protein. DEV UL15 is a spliced gene that encodes two products encoded by 2.9 and 1.3 kb transcripts respectively. The UL15 is expressed late during infection. The coding sequences of DEV UL15 are very similar to those of alphaherpesviruses and most similar to the genus Mardivirus. The UL15 and/or UL15.5 accumulate(s) in the cytoplasm during early times post-infection and then are translocated to the nucleus at late times.

Modeling the Syn-Disposition of Nitrogen Donors in Non-Heme Diiron Enzymes. Synthesis, Characterization, and Hydrogen Peroxide Reactivity of Diiron(III) Complexes with the Syn N-Donor Ligand H2BPG2DEV

PubMed Central

Friedle, Simone; Kodanko, Jeremy J.; Morys, Anna J.; Hayashi, Takahiro; Moënne-Loccoz, Pierre; Lippard, Stephen J.

2009-01-01

In order to model the syn disposition of histidine residues in carboxylate-bridged non-heme diiron enzymes, we prepared a new dinucleating ligand, H2BPG2DEV, that provides this geometric feature. The ligand incorporates biologically relevant carboxylate functionalities, which have not been explored as extensively as nitrogen-only analogs. Three novel oxo-bridged diiron(III) complexes [Fe2(μ-O)(H2O)2-(BPG2DEV)](ClO4)2 (6), [Fe2(μ-O)(μ-O CAriPrO)(BPG2DEV)](ClO4) (7), and [Fe2(μ-O)(μ-CO3)(BPG2DEV)] (8) were prepared. Single crystal X-ray structural characterization confirms that two pyridines are bound syn with respect to the Fe–Fe vector in these compounds. The carbonato-bridged complex 8 forms quantitatively from 6 in a rapid reaction with gaseous CO2 in organic solvents. A common maroon-colored intermediate (λmax = 490 nm; ε = 1500 M−1 cm−1) forms in reactions of 6, 7, or 8 with H2O2 and NEt3 in CH3CN/H2O solutions. Mass spectrometric analyses of this species, formed using 18O-labeled H2O2, indicate the presence of a peroxide ligand bound to the oxo-bridged diiron(III) center. The Mössbauer spectrum at 90 K of the EPR-silent intermediate exhibits a quadrupole doublet with δ. = 0.58 mm/s and ΔEQ = 0.58 mm/s. The isomer shift is typical for a peroxodiiron(III) species, but the quadrupole splitting parameter is unusually small compared to related complexes. These Mössbauer parameters are comparable to those observed for a peroxo intermediate formed in the reaction of reduced toluene/o-xylene monooxygenase hydroxylase (ToMOH) with dioxygen. Resonance Raman studies reveal an unusually low-energy O–O stretching mode in the peroxo intermediate that is consistent with a short diiron distance. Although peroxodiiron(III) intermediates generated from 6, 7, and 8 are poor O-atom transfer catalysts, they display highly efficient catalase activity, with turnover numbers up to 10,000. In contrast to hydrogen peroxide reactions of diiron(III) complexes that lack a dinucleating ligand, the intermediates generated here could be reformed in significant quantities after a second addition of H2O2, as observed spectroscopically and by mass spectrometry. PMID:19757795

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bartlett, Roscoe A.; Baird, Mark L.; Berrill, Mark A.

This guide describes the structure and setup of the standard VERA development environment (VERA Dev Env) and standard VERA Third Party Libraries (TPLs) that need to be in place before installing many of the VERA simulation components. It describes everything from the initial setup on a new machine to the final build, testing, and installation of VERA components. The goal of this document is to describe how to create the directories and contents outlined in Standard VERA Dev Env Directory Structure and then obtain the remaining VERA source and build, test, and install any of the necessary VERA components onmore » a given system. This document describes the process both for a development version of VERA and for a released tarball of the VERA sources.« less

Update on Development of 360V, 28kWh Lithium-Ion Battery

NASA Technical Reports Server (NTRS)

Davies, Francis; Darcy, Eric; Cowles, Phil; Irlbeck, Brad; Weintritt, John

2005-01-01

Engineering unit submodule batteries (EUSB) the 360V, 28kWh EAPU battery were designed and assembled by COM DEV. These submodules consist of Sony Li-Ion 18650HC cells in a 5P-41S array yielding 180V, 1.4 kWh. Tests of these and of substrings and single cells at COM DEV and at JSC under various performance and abuse conditions demonstrated that performance requirements can be met. The thermal vacuum tests demonstrated that the worst case hot condition is the design driver. Deficiencies in the initial diode protection scheme of the battery were identified as a result of test failures. Potential solutions to the scheme are under development and will be presented.

Paleozoic Assemblage of the Northern Sierra Terrane: New Geochronology And Geochemical Data From the Stitching Late Devonian - Early Carboniferous Bowman Lake Batholith, and Associated Rocks

NASA Astrophysics Data System (ADS)

Powerman, V.; Hanson, R. E.; Girty, G.; Tretiakov, A.

2016-12-01

Previous study (Grove et al., 2008) of detrital zircon ages and the timing of magmatism within the Northern Sierra terrane (NST) suggest that it is exotic relative to western Laurentia, and link it to the Paleozoic Arctic Realm, Baltica and Caledonides. NST is a composite terrane in the North America Cordillera, consisting of four distinct allochthons, thrusted upon each other. As a first step towards the understanding of the origin and tectonic development of the NST we have undertaken the SHRIMP-RG U-Pb zircon dating of the rocks from granites, granodiorites, trondhjemites, tonalites and hypabyssal intrusions, composing the Bowman Lake batholith. The batholith stitches the allochthons of the NST and its crystallization age signifies the timing of juxtaposition SHRIMP-RG analyses from 14 samples yielded an age range of ca. 352-369 Ma, which overlaps the Devonian-Mississipian boundary and constrains the minimum age for amalgamation. Additionally, we have acquired multiple XRF data, favoring the island arc provenance of the Bowman Lake batholith Batholith. Previously proposed ties between NST and Robert Mountains allochthon seem unlikely because the latter was accreted onto the western miogeocline of Laurentia during the Late Dev.-Early Miss. while the NST was most probably still situated within the Arctic Realm. This work has been supported by the grant #14.Z50.31.0017 of the Government of the Russian Federation and by the Russian Foundation for Basic Research grant #15-55-10055. We are grateful to Stanford-USGS SHRIMP-RG center, and personally to Marty Grove and Elizabeth Miller.

CIDR

Science.gov Websites

Consortium Developed Arrays Infinium Human Drug Core Array The Illumina nfinium DrugDev Consortium array drug target discovery, validation and treatment response. Detailed Information on Array Infinium Human

European Solid State Device Research Conference (18th) Held on September 13-16 1988 in Montpellier, France. (ESSDERC 88)

DTIC Science & Technology

1988-09-16

IEEE Trans. Electron Dev., 30, pp 1295 (1983) /2/ K.K. Ng and W.T. Lynch, IEEE Trans. Electron Dev., 34, pp 503 (1987). /3/ P.A. van der Plas, W.C.E...300 20 F Ohm I FRC I 500 170 Ohm INPNICje F 65 F 28 fI Cjc F 100 j 45 I fF hFE I 80 j 80 II IBVEB I 6.5 F 6.5 V BVCE I 6.5 6.5 vI BVCB F 18 I 18 (V I...evaluated include a -Xb RAM, a 1.6GHz universal shift register and an 8 bit DAC with a 1.2ns settling time. A micograph of the DAC is shown in figure 6

Collaborative modeling: the missing piece of distributed simulation

NASA Astrophysics Data System (ADS)

Sarjoughian, Hessam S.; Zeigler, Bernard P.

1999-06-01

The Department of Defense overarching goal of performing distributed simulation by overcoming geographic and time constraints has brought the problem of distributed modeling to the forefront. The High Level Architecture standard is primarily intended for simulation interoperability. However, as indicated, the existence of a distributed modeling infrastructure plays a fundamental and central role in supporting the development of distributed simulations. In this paper, we describe some fundamental distributed modeling concepts and their implications for constructing successful distributed simulations. In addition, we discuss the Collaborative DEVS Modeling environment that has been devised to enable graphically dispersed modelers to collaborate and synthesize modular and hierarchical models. We provide an actual example of the use of Collaborative DEVS Modeler in application to a project involving corporate partners developing an HLA-compliant distributed simulation exercise.

The Proposed Doppler Electron Velocimeter and the Need for Nanoscale Dynamics

DOE PAGES

Reu, Phillip L.

2007-05-01

As engineering challenges grow in the ever-shrinking world of nano-design, methods of making dynamic measurements of nano-materials and systems become more important. The Doppler electron velocimeter (DEV) is a new measurement concept motivated by the increasing importance of nano-dynamics. Nano-dynamics is defined in this context as any phenomenon that causes a dynamically changing phase in an electron beam, and includes traditional mechanical motion, as well as additional phenomena including changing magnetic and electric fields. The DEV is only a theoretical device at this point. Lastly, this article highlights the importance of pursuing nano-dynamics and presents a case that the electronmore » microscope and its associated optics are a viable test bed to develop this new measurement tool.« less

Genetics Home Reference: Fukuyama congenital muscular dystrophy

MedlinePlus

... Fujii T, Aiba H, Toda T. Seizure-genotype relationship in Fukuyama-type congenital muscular dystrophy. Brain Dev. ... for Links Data Files & API Site Map Subscribe Customer Support USA.gov Copyright Privacy Accessibility FOIA Viewers & ...

Genetics Home Reference: CHOPS syndrome

MedlinePlus

... complex (SEC) and MLL in development and disease. Genes Dev. 2011 Apr 1;25(7):661-72. doi: 10.1101/gad.2015411. Review. Citation ... are genome editing and CRISPR-Cas9? What is precision medicine? What ...

Methodology for the placement of maintenance area headquarters.

DOT National Transportation Integrated Search

1985-01-01

A methodology for strategically locating Virginia Department of Highways and Transportation maintenance area headquarters throughout the state was developed and pilot tested in the Charlottesville Residency (Albemarle and Greene counties). In the dev...

Genetics Home Reference: Smith-Magenis syndrome

MedlinePlus

... segment most often includes approximately 3.7 million DNA building blocks (base pairs), also written as 3. ... AM, Lupski JR, Potocki L. Cognitive and adaptive behavior profiles in Smith-Magenis syndrome. J Dev Behav ...

75 FR 30405 - Change in Bank Control Notices; Acquisition of Shares of Bank or Bank Holding Companies

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-01

... Revocable Trust, James E. Ukrop, Trustee; Robert Stephen Ukrop; The Amended and Restated Robert Stephen Ukrop Revocable Trust, Robert Stephen Ukrop, Trustee; Robert Scott Ukrop; The Amendment and Restatement.... Ukrop; The Robert Stephen Ukrop, Revocable Trust, Joseph Ukrop, Jr., Trustee; Jacquelin Ukrop Aronson...

The influence of self-assembling supramolecular structures on the passive membrane transport of ion-paired molecules.

PubMed

Benaouda, F; Brown, M B; Shah, B; Martin, G P; Jones, S A

2012-12-15

Weak ion-ion interactions, such as those associated with ion-pair formation, are difficult to isolate and characterise in the liquid state, but they have the potential to alter significantly the physicochemical behaviour of molecules in solution. The aim of this work was to gain a better understanding of how ion-ion interactions influenced passive membrane transport. The test system was composed of propylene (PG) glycol, water and diclofenac diethylamine (DDEA). Infrared spectroscopy was employed to determine the nature of the DDEA ion-pair interactions and the drug-vehicle association. Passive transport was assessed using homogeneous synthetic membranes. Solution-state analysis demonstrated that the ion-pair was unperturbed by vehicle composition changes, but the solvent-DDEA interactions were modified. DDEA-PG/water hydrogen bonding influenced the ion-pair solubility (X(dev)) and the solvent interactions slowed transport rate in PG-rich vehicles (0.84±0.05 μg cm(-2) h(-1), at ln(X(dev))=0.57). In water-rich co-solvents, the presence of strong water structuring facilitated a significant increase (p<0.05) in transmembrane penetration rate (e.g. 4.33±0.92 μg cm(-2) h(-1), at ln(X(dev))=-0.13). The data demonstrates that weak ion-ion interactions can result in the embedding of polar entities within a stable solvent complex and spontaneous supramolecular assembly should be considered when interpreting transmembrane transport processes of ionic molecules. Copyright © 2012 Elsevier B.V. All rights reserved.

Duck virus enteritis (duck plague) - a comprehensive update.

PubMed

Dhama, Kuldeep; Kumar, Naveen; Saminathan, Mani; Tiwari, Ruchi; Karthik, Kumaragurubaran; Kumar, M Asok; Palanivelu, M; Shabbir, Muhammad Zubair; Malik, Yashpal Singh; Singh, Raj Kumar

2017-12-01

Duck virus enteritis (DVE), also called duck plague, is one of the major contagious and fatal diseases of ducks, geese and swan. It is caused by duck enteritis virus (DEV)/Anatid herpesvirus-1 of the genus Mardivirus, family Herpesviridae, and subfamily Alpha-herpesvirinae. Of note, DVE has worldwide distribution, wherein migratory waterfowl plays a crucial role in its transmission within and between continents. Furthermore, horizontal and/ or vertical transmission plays a significant role in disease spread through oral-fecal discharges. Either of sexes from varying age groups of ducks is vulnerable to DVE. The disease is characterized by sudden death, vascular damage and subsequent internal hemorrhage, lesions in lymphoid organs, digestive mucosal eruptions, severe diarrhea and degenerative lesions in parenchymatous organs. Huge economic losses are connected with acute nature of the disease, increased morbidity and mortality (5%-100%), condemnations of carcasses, decreased egg production and hatchability. Although clinical manifestations and histopathology can provide preliminary diagnosis, the confirmatory diagnosis involves virus isolation and detection using serological and molecular tests. For prophylaxis, both live-attenuated and killed vaccines are being used in broiler and breeder ducks above 2 weeks of age. Since DEV is capable of becoming latent as well as shed intermittently, recombinant subunit and DNA vaccines either alone or in combination (polyvalent) are being targeted for its benign prevention. This review describes DEV, epidemiology, transmission, the disease (DVE), pathogenesis, and advances in diagnosis, vaccination and antiviral agents/therapies along with appropriate prevention and control strategies.

Robert S. Nelson | NREL

Science.gov Websites

S. Nelson Photo of Robert S. Nelson Robert Nelson Researcher II-Biological Science Robert.Nelson recombinant proteins. His current work is focused on the biological conversion of lignocellulose to advanced

34 CFR 654.1 - What is the Robert C. Byrd Honors Scholarship Program?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 3 2011-07-01 2011-07-01 false What is the Robert C. Byrd Honors Scholarship Program...) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION ROBERT C. BYRD HONORS SCHOLARSHIP PROGRAM General § 654.1 What is the Robert C. Byrd Honors Scholarship Program? Under the Robert C. Byrd Honors...

34 CFR 654.1 - What is the Robert C. Byrd Honors Scholarship Program?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 3 2012-07-01 2012-07-01 false What is the Robert C. Byrd Honors Scholarship Program...) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION ROBERT C. BYRD HONORS SCHOLARSHIP PROGRAM General § 654.1 What is the Robert C. Byrd Honors Scholarship Program? Under the Robert C. Byrd Honors...

34 CFR 654.1 - What is the Robert C. Byrd Honors Scholarship Program?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 3 2013-07-01 2013-07-01 false What is the Robert C. Byrd Honors Scholarship Program...) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION ROBERT C. BYRD HONORS SCHOLARSHIP PROGRAM General § 654.1 What is the Robert C. Byrd Honors Scholarship Program? Under the Robert C. Byrd Honors...

34 CFR 654.1 - What is the Robert C. Byrd Honors Scholarship Program?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 3 2014-07-01 2014-07-01 false What is the Robert C. Byrd Honors Scholarship Program...) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION ROBERT C. BYRD HONORS SCHOLARSHIP PROGRAM General § 654.1 What is the Robert C. Byrd Honors Scholarship Program? Under the Robert C. Byrd Honors...

34 CFR 654.1 - What is the Robert C. Byrd Honors Scholarship Program?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false What is the Robert C. Byrd Honors Scholarship Program...) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION ROBERT C. BYRD HONORS SCHOLARSHIP PROGRAM General § 654.1 What is the Robert C. Byrd Honors Scholarship Program? Under the Robert C. Byrd Honors...

Effects of private transportation improvements on economic development.

DOT National Transportation Integrated Search

2012-09-01

In this project, we explored opportunities and effects of public-private or private-private partnerships for mobility improvements (incl. alternative fueled shuttles and IT infrastructure) and assessed their effects on local and regional economic dev...

Alcohol ignition interlock service support

DOT National Transportation Integrated Search

1992-12-01

Author's abstract: This Technical Report was produced under Contract No. DTNH22-89-C-07009 for the National Highway Traffic Safety Administration. Under that same contract, a draft set of model specifications for Breath Alcohol Ignition Interlock Dev...

Genetics Home Reference: fragile X syndrome

MedlinePlus

... Citation on PubMed Koukoui SD, Chaudhuri A. Neuroanatomical, molecular genetic, and behavioral correlates of fragile X syndrome. Brain ... GJ, Dictenberg J. The fragile X syndrome: from molecular genetics to neurobiology. Ment Retard Dev Disabil Res Rev. ...

Evaluation of Vehicle Detection Systems for Traffic Signal Operations

DOT National Transportation Integrated Search

2016-10-16

Typical vehicle detection systems used in traffic signal operations are comprised of inductive loop detectors. Because of costs, installation challenges, and operation and maintenance issues, many alternative non-intrusive systems have been dev...

Investigation of sediment suspension technology.

DOT National Transportation Integrated Search

2016-10-01

The goal of the project was to critically review existing literature to access currently available devices, the : identification of areas of improvement for future designs, and the outline of a new-generation cohesive sediment : erosion measuring dev...

An Architecture for the Electronic Church: Oral Roberts University in Tulsa, Oklahoma.

PubMed

Grubiak, Margaret M

2016-04-01

More than a university, Oral Roberts University in Tulsa, Oklahoma, was also the headquarters for evangelist Oral Roberts's electronic church. The electronic church in America, dominated by Christian evangelicals, used technology to spread the Gospel over radio airways and television signals to a dispersed audience. Yet evangelicals like Roberts also constructed ambitious campuses in real space and time. The architecture of Oral Roberts University visualized a modern and "populuxe" image for the electronic church in the 1960s and 1970s. The university's Prayer Tower purposely alluded to the Seattle Space Needle, aligning religion and the Space Age, and the campus's white, gold, and black color palette on late modern buildings created an image of aspirational luxury, conveying Roberts's health and wealth gospel. Oral Roberts University served as a sound stage for Roberts's radio and television shows, a pilgrimage point for his audience, and a university dedicated to training evangelicals in the electronic church.

Calibration of controlling input models for pavement management system.

DOT National Transportation Integrated Search

2013-07-01

The Oklahoma Department of Transportation (ODOT) is currently using the Deighton Total Infrastructure Management System (dTIMS) software for pavement management. This system is based on several input models which are computational backbones to dev...

Journal of Transportation and Statistics

DOT National Transportation Integrated Search

2006-01-01

The journal serves the transportation community by increasing the understanding of the role of transportation in society, its function in the economy, and its interactions with the environment. In addition, the JTS provides a forum for the latest dev...

Genetics Home Reference: dyserythropoietic anemia and thrombocytopenia

MedlinePlus

... PubMed Crispino JD. GATA1 in normal and malignant hematopoiesis. Semin Cell Dev Biol. 2005 Feb;16(1): ... GATA1 function, a paradigm for transcription factors in hematopoiesis. Mol Cell Biol. 2005 Feb;25(4):1215- ...

Suppliers solve processing problems

USDA-ARS?s Scientific Manuscript database

The year's IFT food expo showcased numerous companies and organizations offering solutions to food processing needs and challenges. From small-scale unit operations to commercial-scale equipment lines, exhibitors highlighted both traditional and novel food processing operations fro food product dev...

Status of Advanced Propulsion Technology in Japan

DOT National Transportation Integrated Search

1982-03-01

This report describes the efforts of the Japanese transit industry, which includes manufacturers and transit operators, in the area of advanced propulsion systems for urban rail vehicles. It presents different chopper system designs, new ac drive dev...

imDEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel.

PubMed

Grapov, Dmitry; Newman, John W

2012-09-01

Interactive modules for Data Exploration and Visualization (imDEV) is a Microsoft Excel spreadsheet embedded application providing an integrated environment for the analysis of omics data through a user-friendly interface. Individual modules enables interactive and dynamic analyses of large data by interfacing R's multivariate statistics and highly customizable visualizations with the spreadsheet environment, aiding robust inferences and generating information-rich data visualizations. This tool provides access to multiple comparisons with false discovery correction, hierarchical clustering, principal and independent component analyses, partial least squares regression and discriminant analysis, through an intuitive interface for creating high-quality two- and a three-dimensional visualizations including scatter plot matrices, distribution plots, dendrograms, heat maps, biplots, trellis biplots and correlation networks. Freely available for download at http://sourceforge.net/projects/imdev/. Implemented in R and VBA and supported by Microsoft Excel (2003, 2007 and 2010).

Mapping CMMI Level 2 to Scrum Practices: An Experience Report

NASA Astrophysics Data System (ADS)

Diaz, Jessica; Garbajosa, Juan; Calvo-Manzano, Jose A.

CMMI has been adopted advantageously in large companies for improvements in software quality, budget fulfilling, and customer satisfaction. However SPI strategies based on CMMI-DEV require heavy software development processes and large investments in terms of cost and time that medium/small companies do not deal with. The so-called light software development processes, such as Agile Software Development (ASD), deal with these challenges. ASD welcomes changing requirements and stresses the importance of adaptive planning, simplicity and continuous delivery of valuable software by short time-framed iterations. ASD is becoming convenient in a more and more global, and changing software market. It would be greatly useful to be able to introduce agile methods such as Scrum in compliance with CMMI process model. This paper intends to increase the understanding of the relationship between ASD and CMMI-DEV reporting empirical results that confirm theoretical comparisons between ASD practices and CMMI level2.

The NeuroDevNet Autism Spectrum Disorders Demonstration Project.

PubMed

Zwaigenbaum, Lonnie; Scherer, Stephen; Szatmari, Peter; Fombonne, Eric; Bryson, Susan E; Hyde, Krista; Anagnostou, Evdokia; Anognostou, Evdokia; Brian, Jessica; Evans, Alan; Hall, Geoff; Nicholas, David; Roberts, Wendy; Smith, Isabel; Vaillancourt, Tracy; Volden, Joanne

2011-03-01

The NeuroDevNet Autism Spectrum Disorder Demonstration Project interfaces at many levels with the network's research themes and priorities. Our interdisciplinary team aims to improve understanding of genetic factors underlying vulnerability to autism spectrum disorders (ASDs) to develop better diagnostic strategies and, ultimately, to pinpoint molecular pathways relevant to developing biologically based treatments. Linking our existing longitudinal ASD cohorts with both genetics and neuroimaging studies will provide, for the first time, integrated data on how the genetic variation influences brain and behavioral development in ASD. Importantly, as our science progresses and we translate this information to the health care system, we will also educate policy makers, media, and business, so an informed society is prepared to capitalize on new genomic advances and effectively integrate these into health services for the broader community. We believe that this research has the potential to transform assessment and care for individuals with ASD. Copyright © 2011 Elsevier Inc. All rights reserved.

The Future of Educational Research.

ERIC Educational Resources Information Center

Farley, Frank H., Ed.

1982-01-01

Seven past presidents of the American Educational Research Association discuss trends and the probable nature of educational research in the 1980s. Authors include N.L. Gage, Benjamin S. Bloom, David R. Krathwohl, Robert M. Gagne, Robert Glaser, Robert Ebel, and Robert L. Thorndike. (GC)

The GenDev Curriculum Development Workshop.

PubMed

D'cunha, J

1997-01-01

This article describes the second Curriculum Development Workshop held in May 1997 at the Asian Institute of Technology (AIT) in Bangkok, Thailand. The workshop aimed to review critically and restructure the Gender and Development Studies (GenDev) curriculum and to assess AIT's role in training gender experts for the region. Participants included 22 people from 16 countries in Asia, Europe, and the US who were teaching graduate students about gender issues and who were activists with nongovernmental organizations working on gender issues. It was determined that the following were required courses: Culture, Knowledge and Gender Relations; Gender, Technology, and Development; Principles of Gender Research and Methodology in Science and Technology; and Gender Analysis and Field Methods. Other suggested core courses included: Gender and Natural Resource Management; Enterprise Management, Technology, and Gender; Gender and Agrarian Reform; Urbanization: A Gender Perspective; Gender-Responsive Development Planning; and Gender and Economic Change: Past and Present Concerns. Participants distinguished between GenDev courses offered to anyone attending AIT and training courses designed to produce gender experts in the region. The aim of training courses for AIT graduate students was to sensitize potential managers, technologists, and others on gender issues and to create awareness of the importance of including gender perspectives within decision-making, policy formation, and implementation. Training courses to produce gender experts should be directed to those with a prior background in gender studies and include gender analysis in field methods. Participants agreed that there should be an independent and autonomous field of gender and development studies. Participants made six recommendations for such a field of study.

Making connections : intermodal links in the public transportation system

DOT National Transportation Integrated Search

2007-09-01

Since at least 1991, federal transportation policy has sought to encourage intermodal connections the links that allow passengers to switch from one mode of public transportation to another. The intermodal terminal is a key building block for dev...

Locomotive crashworthiness research : volume 5 : cab car crashworthiness report

DOT National Transportation Integrated Search

1996-03-01

Models used to analyze locomotive crashworthiness are modified for application to control cab cars of the types used for intercity and commuter rail passenger service. An existing control cab car is analyzed for crashworthiness based on scenarios dev...

Directors of Health Promotion and Education

MedlinePlus

... Dev Career Center DHPE Webinars Systems Change for Health School Employee Wellness CHES/Attendee Certificates Calendar of Events Internships ... Calendar of Events Career Center Policy Briefs School Employee Wellness Links to Other ... of Health Promotion and Education (DHPE) News & Updates more & ...

The Volpe National Transportation Systems Center : an introduction

DOT National Transportation Integrated Search

1997-01-01

The Volpe National Transportation Systems Center (Volpe Center) has a long and proud history of defining problems and developing solutions. For more than 25 years, the Center has been applying its unique technical knowledge in planning, research, dev...

77 FR 40609 - Robert D. Willis Power Rate

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-10

... DEPARTMENT OF ENERGY Southwestern Power Administration Robert D. Willis Power Rate AGENCY... proposed Robert D. Willis rate schedule, which is supported by a power repayment study, to recover the... existing Robert D. Willis rate for the period October 1, 2008 through September 30, 2012. See 127 FERC...

Getting to Negotiations in Syria: The Shadow of the Future and the Syrian Civil War

DTIC Science & Technology

2014-01-01

parties are that there will be a tomorrow, the more willing they will become to talk about it. As Robert Axelrod and Robert O. Keohane write, “The more...N.J.: Princeton University Press, 2002. 35 Walter, 1997, p. 335. 36 Walter, 1997, p. 336. 37 Robert Axelrod and Robert O. Keohane , “Achieving...sovereign states may choose to cooperate under conditions of anarchy. According to Robert Axel- The literature has focused on conditions prior to or

Guidelines for development of the Iowa statewide transportation improvement program (STIP). Revised.

DOT National Transportation Integrated Search

2004-01-01

The Transportation Equity Act for the 21st Century (TEA-21) continues the Intermodal Surface Transportation Efficiency Act of 1991's requirement for an extensive, ongoing cooperative planning effort for programming federal funding. Iowa's STIP is dev...

Connection details for prefabricated bridge elements and systems.

DOT National Transportation Integrated Search

2009-03-30

Prefabricated components of a bridge produced off-site can be assembled quickly, and can reduce design time and cost, minimizing forming, minimize lane closure time and/or possibly eliminate the need for a temporary bridge. This document has been dev...

SITE PROGRAM EVALUATION OF THE SONOTECH PULSE COMBUSTION BURNER TECHNOLOGY - TECHNICAL RESULTS

EPA Science Inventory

A series of demonstration tests was performed at the Environmental Protection Agency's (EPA's) Incineration Research Facility (IRF) under the Superfund Innovative Technology Evaluation (SITE) program. These tests, twelve in all, evaluated a pulse combustion burner technology dev...

Growing cooler : the evidence on urban development and climate change

DOT National Transportation Integrated Search

1997-10-01

This new book documents how key changes in land development patterns could help reduce vehicle : greenhouse gas emissions. Based on a comprehensive review of dozens of studies by leading urban : planning researchers, the book concludes that urban dev...

DETERMINATION OF ELEMENTAL COMPOSITIONS BY HIGH RESOLUTION MASS SPECTROMETRY WITHOUT MASS CALIBRANTS

EPA Science Inventory

Widely applicable mass calibrants, including perfluorokerosene, are available for gas-phase introduction of analytes ionized by electron impact (EI) prior to analysis using high resolution mass spectrometry. Unfortunately, no all-purpose calibrants are available for recently dev...

Earplug rankings based on the protector-attenuation rating (P-AR).

DOT National Transportation Integrated Search

1975-01-01

Forty-five attenuation spectra for earplugs were classified according to a simplified method designed to produce single-number ratings of noise reduction. The rating procedure was applied to the mean attenuation scores, to mean-minus-one-standard-dev...

Using HexSim to link demography and genetics in animal and plant simulations

EPA Science Inventory

Simulation models are essential for understanding the effects of land management practices and environmental drivers, including landscape change, shape population genetic structure and persistence probabilities. The emerging field of eco-evolutionary modeling is beginning to dev...

76 FR 48898 - Robert Leigh Kale, M.D., Decision and Order

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-09

... DEPARTMENT OF JUSTICE Drug Enforcement Administration Robert Leigh Kale, M.D., Decision and Order... Enforcement Administration, issued an Order to Show Cause to Robert Leigh Kale, M.D. (Registrant), of Fort... Certificate of Registration, BK9514375, issued to Robert Leigh Kale, M.D., be, and it hereby is, revoked. I...

Robert Preus | NREL

Science.gov Websites

| 303-384-7284 Robert's expertise is in design and manufacture of small and midsized wind generators certification support for small wind manufacturers. Robert has 28 years of experience in wind energy. He led the section for wind in the National Electrical Code. In 2010, Robert received the Small Wind Advocate award

Radiographic Assessment of the Robert and Lateral Views in Trapeziometacarpal Osteoarthrosis.

PubMed

Oheb, Jonathan; Lansinger, Yuri; Jansen, Joshua A; Nguyen, Jimmy Q; Porembski, Margaret A; Rayan, Ghazi M

2015-01-01

To evaluate the effectiveness of the Robert view in assessing trapeziometacarpal arthrosis and to compare the accuracy of the Robert and lateral views in staging trapeziometacarpal (TM) joint arthrosis. Patient demographics were obtained. Four participating raters reviewed 62 randomly selected thumb x-rays of patients presenting with thumb TM joint pain. Lateral and Robert-hyperpronation views were assessed using an analysis of 13 criteria. X-rays of 62 thumbs for 58 patients were evaluated. The average patients' age was 64 (47-87) and 51 (80%) were females. The majority of X-rays evaluated fell into stage 3. Stage 2 was the second most common level of arthritis encountered and the least was stage 1. More osteophytes were encountered in the trapezium than metacarpal on both the Robert and lateral views. The Robert view was superior in detecting osteophytes on the trapezium than the lateral view. Osteophyte size varied from 1.7 to 2 mm. The lateral view displayed 61 cases with dorsal metacarpal subluxation (98%). The Robert view displayed 48 cases (77%) with radial metacarpal subluxation and 9 cases (15%) with ulnar metacarpal subluxation. Thumb metacarpal adduction deformity was encountered on the lateral view in 20 cases (32%) whereas on the Robert view it was encountered in 14 cases (23%). Subchondral sclerosis was encountered on the Robert view in 56 thumbs (90%) while it was seen on the lateral view in 52 thumbs (84%). Pantrapezial arthritis involving the STT joint was encountered equally in 16 cases (26%) on the Robert view and the lateral views. The study found a moderate level of interrater reliability on both the lateral and Robert views. With the exception of osteophytes encountered on the trapezium versus the metacarpal, there were no other statistically significant findings. This study confirms that each of the Robert and lateral views offer unique information and combining both views enhances the ability to assess radiographic disease severity, and should be the recommended set of X-rays for assessing TM osteoarthrosis.

76 FR 71369 - Robert G. Crummie, M.D.; Decision and Order

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-17

... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 10-60] Robert G. Crummie, M.D... Registration, BC2964965, issued to Robert G. Crummie, M.D., be, and it hereby is, revoked. I further order that any pending application of Robert G. Crummie, M.D., to renew or modify his registration, be, and it...

DEMONSTRATION BULLETIN: TEXACO GASIFICATION PROCESS TEXACO, INC.

EPA Science Inventory

The Texaco Gasification Process (TGP) has operated commercially for nearly 45 years on feeds such as natural gas, liquid petroleum fractions, coal, and petroleum coke. More than 45 plants are either operational or under development in the United States and abroad. Texaco has dev...

Load and resistance factor design of bridge foundations accounting for pile group-soil interaction.

DOT National Transportation Integrated Search

2015-11-01

Pile group foundations are used in most foundation solutions for transportation structures. Rigorous and reliable pile design methods are : required to produce designs whose level of safety (probability of failure) is known. By utilizing recently dev...

A MANAGEMENT SUPPORT SYSTEM FOR GREAT LAKES COASTAL WETLANDS

EPA Science Inventory

The Great Lakes National Program Office in conjunction with the Great Lakes Commission and other researchers is leading a large scale collaborative effort that will yield, in unprecedented detail, a management support system for Great Lakes coastal wetlands. This entails the dev...

Aviation Mechanic General, Airframe, and Powerplant Knowledge Test Guide

DOT National Transportation Integrated Search

1995-01-01

The FAA has available hundreds of computer testing centers nationwide. These testing centers offer the full range of airman knowledge tests. Refer to appendix 1 in this guide for a list of computer testing designees. This knowledge test guide was dev...

Cost-Effectiveness of Aflatoxin Control Methods: Economic Incentives

USDA-ARS?s Scientific Manuscript database

Multiple sectors in U.S. crop industries – growers, elevators, handlers/shellers, processors, distributors, and consumers – are affected by aflatoxin contamination of commodities, and have the potential to control it. Aflatoxin control methods at both preharvest and postharvest levels have been dev...

Supporting Collaborative Model and Data Service Development and Deployment with DevOps

NASA Astrophysics Data System (ADS)

David, O.

2016-12-01

Adopting DevOps practices for model service development and deployment enables a community to engage in service-oriented modeling and data management. The Cloud Services Integration Platform (CSIP) developed the last 5 years at Colorado State University provides for collaborative integration of environmental models into scalable model and data services as a micro-services platform with API and deployment infrastructure. Originally developed to support USDA natural resource applications, it proved suitable for a wider range of applications in the environmental modeling domain. While extending its scope and visibility it became apparent community integration and adequate work flow support through the full model development and application cycle drove successful outcomes.DevOps provide best practices, tools, and organizational structures to optimize the transition from model service development to deployment by minimizing the (i) operational burden and (ii) turnaround time for modelers. We have developed and implemented a methodology to fully automate a suite of applications for application lifecycle management, version control, continuous integration, container management, and container scaling to enable model and data service developers in various institutions to collaboratively build, run, deploy, test, and scale services within minutes.To date more than 160 model and data services are available for applications in hydrology (PRMS, Hydrotools, CFA, ESP), water and wind erosion prediction (WEPP, WEPS, RUSLE2), soil quality trends (SCI, STIR), water quality analysis (SWAT-CP, WQM, CFA, AgES-W), stream degradation assessment (SWAT-DEG), hydraulics (cross-section), and grazing management (GRAS). In addition, supporting data services include soil (SSURGO), ecological site (ESIS), climate (CLIGEN, WINDGEN), land management and crop rotations (LMOD), and pesticides (WQM), developed using this workflow automation and decentralized governance.

Young Children's Reasoning About Physical & Behavioural Family Resemblance: Is There a Place for a Precursor Model of Inheritance?

NASA Astrophysics Data System (ADS)

Ergazaki, Marida; Alexaki, Aspa; Papadopoulou, Chrysa; Kalpakiori, Marieleni

2014-02-01

This paper aims at exploring (a) whether preschoolers recognize that offspring share physical traits with their parents due to birth and behavioural ones due to nurture, and (b) whether they seem ready to explain shared physical traits with a `pre-biological' causal model that includes the contribution of both parents and a rudimentary notion of genes. This exploration is supposed to provide evidence for our next step, which is the development of an early years' learning environment about inheritance. Conducting individual, semi-structured interviews with 90 preschoolers (age 4.5-5.5) of four public kindergartens in Patras, we attempted to trace their reasoning about (a) whether and why offspring share physical and behavioural traits with parents and (b) which mechanism could better explain the shared physical traits. The probes were a modified six-case version of Solomon et al. (Child Dev 67:151-171, 1996) `adoption task, as well as a three-case task based on Springer's (Child Dev 66:547-558, 1995) `mechanism task' and on Solomon and Johnson's (Br J Dev Psychol 18(1):81-96, 2000) idea of genes as a `conceptual placeholder'. The qualitative and quantitative analysis of the interviews showed overlapping reasoning about the origin of physical and behavioural family resemblance. Nevertheless, we did trace the `birth-driven' argument for the attribution of the offspring's physical traits to the biological parents, as well as a preference for the `pre-biological' model that introduces a rudimentary idea of genes in order to explain shared physical traits between parents and offspring. The findings of the study and the educational implications are thoroughly discussed.

Evaluating the Hydrologic Performance of Low Impact Development Scenarios in a Micro Urban Catchment.

PubMed

Li, Chunlin; Liu, Miao; Hu, Yuanman; Han, Rongqing; Shi, Tuo; Qu, Xiuqi; Wu, Yilin

2018-02-05

As urbanization progresses, increasingly impervious surfaces have changed the hydrological processes in cities and resulted in a major challenge for urban stormwater control. This study uses the urban stormwater model to evaluate the performance and costs of low impact development (LID) scenarios in a micro urban catchment. Rainfall-runoff data of three rainfall events were used for model calibration and validation. The pre-developed (PreDev) scenario, post-developed (PostDev) scenario, and three LID scenarios were used to evaluate the hydrologic performance of LID measures. Using reduction in annual runoff as the goal, the best solutions for each LID scenario were selected using cost-effectiveness curves. The simulation results indicated that the three designed LID scenarios could effectively reduce annual runoff volumes and pollutant loads compared with the PostDev scenario. The most effective scenario (MaxPerf) reduced annual runoff by 53.4%, followed by the sponge city (SpoPerf, 51.5%) and economy scenarios (EcoPerf, 43.1%). The runoff control efficiency of the MaxPerf and SpoPerf scenarios increased by 23.9% and 19.5%, respectively, when compared with the EcoPerf scenario; however, the costs increased by 104% and 83.6%. The reduction rates of four pollutants (TSS, TN, TP, and COD) under the MaxPerf scenario were 59.8-61.1%, followed by SpoPerf (53.9-58.3%) and EcoPerf (42.3-45.4%), and the costs of the three scenarios were 3.74, 3.47, and 1.83 million yuan, respectively. These results can provide guidance to urban stormwater managers in future urban planning to improve urban water security.

Evaluating the Hydrologic Performance of Low Impact Development Scenarios in a Micro Urban Catchment

PubMed Central

Li, Chunlin; Liu, Miao; Hu, Yuanman; Han, Rongqing; Shi, Tuo; Qu, Xiuqi; Wu, Yilin

2018-01-01

As urbanization progresses, increasingly impervious surfaces have changed the hydrological processes in cities and resulted in a major challenge for urban stormwater control. This study uses the urban stormwater model to evaluate the performance and costs of low impact development (LID) scenarios in a micro urban catchment. Rainfall-runoff data of three rainfall events were used for model calibration and validation. The pre-developed (PreDev) scenario, post-developed (PostDev) scenario, and three LID scenarios were used to evaluate the hydrologic performance of LID measures. Using reduction in annual runoff as the goal, the best solutions for each LID scenario were selected using cost-effectiveness curves. The simulation results indicated that the three designed LID scenarios could effectively reduce annual runoff volumes and pollutant loads compared with the PostDev scenario. The most effective scenario (MaxPerf) reduced annual runoff by 53.4%, followed by the sponge city (SpoPerf, 51.5%) and economy scenarios (EcoPerf, 43.1%). The runoff control efficiency of the MaxPerf and SpoPerf scenarios increased by 23.9% and 19.5%, respectively, when compared with the EcoPerf scenario; however, the costs increased by 104% and 83.6%. The reduction rates of four pollutants (TSS, TN, TP, and COD) under the MaxPerf scenario were 59.8–61.1%, followed by SpoPerf (53.9–58.3%) and EcoPerf (42.3–45.4%), and the costs of the three scenarios were 3.74, 3.47 and 1.83 million yuan, respectively. These results can provide guidance to urban stormwater managers in future urban planning to improve urban water security. PMID:29401747

SPATIAL ACCURACY: A CRITICAL FACTOR IN GIS-RELATED ACTIVITIES

EPA Science Inventory

Onsite analyses are critical to making timely decisions. The results of these decisions may not be realized for many years. In order to increase the value of onsite analyses and to create and utilize meaningful environmental models, the Environmental Protection Agency (EPA) dev...

Coast Guard : update on Marine Information for Safety and Law Enforcement System

DOT National Transportation Integrated Search

2001-10-01

The Coast Guard is developing a web-based information system to replace an aging computer system that it uses to track safety and law-enforcement actions involving commercial and recreational vessels. In 1995 the Coast Guard awarded a contract to dev...

Development of the Comprehensive General Parenting Questionnaire for caregivers of 5-13 year olds

USDA-ARS?s Scientific Manuscript database

Despite the large number of parenting questionnaires, considerable disagreement exists about how to best assess parenting. Most of the instruments only assess limited aspects of parenting. To overcome this shortcoming, the "Comprehensive General Parenting Questionnaire" (CGPQ) was systematically dev...

Petrotac bridge deck waterproofing membrane on Five Mile Creek Bridge : first interim report.

DOT National Transportation Integrated Search

1986-09-01

During the 1970's, the Oregon State Highway Division was involved in a Federally funded experimental program to evaluate various waterproofing membrane systems for bridge decks. Through this program, a list of approved products and/or systems was dev...

Calibration of region-specific gates pile driving formula for LRFD : final report 561.

DOT National Transportation Integrated Search

2016-05-01

This research project proposes new DOTD pile driving formulas for pile capacity verification using pile driving blow : counts obtained at either end-of-initial driving (EOID) or at the beginning-of-restrike (BOR). The pile driving : formulas were dev...

Durability of certain configurations for providing skid resistance on concrete pavements.

DOT National Transportation Integrated Search

1974-01-01

The main objective of this study was to establish the factors that influence the durability of the surface configurations that are used or can be used to provide high and long lasting skid resistance for portland cement concrete pavements. In the dev...

Coaching for Better (Software) Buying Power in an Agile World

DTIC Science & Technology

2013-06-01

believes that DevOps , the process of warfighters and developers work- ing together throughout the project, is superior to volumes of detailed...ride on the Consolidated Afloat Networks and Enterprise Services (CANES) infrastructure. This transformation is not easy. It requires a change in

imDEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel

PubMed Central

Grapov, Dmitry; Newman, John W.

2012-01-01

Summary: Interactive modules for Data Exploration and Visualization (imDEV) is a Microsoft Excel spreadsheet embedded application providing an integrated environment for the analysis of omics data through a user-friendly interface. Individual modules enables interactive and dynamic analyses of large data by interfacing R's multivariate statistics and highly customizable visualizations with the spreadsheet environment, aiding robust inferences and generating information-rich data visualizations. This tool provides access to multiple comparisons with false discovery correction, hierarchical clustering, principal and independent component analyses, partial least squares regression and discriminant analysis, through an intuitive interface for creating high-quality two- and a three-dimensional visualizations including scatter plot matrices, distribution plots, dendrograms, heat maps, biplots, trellis biplots and correlation networks. Availability and implementation: Freely available for download at http://sourceforge.net/projects/imdev/. Implemented in R and VBA and supported by Microsoft Excel (2003, 2007 and 2010). Contact: John.Newman@ars.usda.gov Supplementary Information: Installation instructions, tutorials and users manual are available at http://sourceforge.net/projects/imdev/. PMID:22815358

Zebrafish embryo developmental toxicology assay.

PubMed

Panzica-Kelly, Julieta M; Zhang, Cindy X; Augustine-Rauch, Karen

2012-01-01

A promising in vitro zebrafish developmental toxicology assay was generated to test compounds for their teratogenic potential. The assay's predictivity is approximately 87% in AB strain fish (Brannen KC et al., Birth Defects Res B Dev Reprod Toxicol 89:66-77, 2010). The procedure entails exposing dechorionated gastrulation-stage embryos to a range of compound concentrations for 5 days throughout embryonic and larva development. The larvae are evaluated for viability in order to identify an LC25 (the compound concentration in which 25% lethality is observed) and morphological anomalies using a numerical score system to identify the NOAEL (no observed adverse effect level). These values are used to calculate the teratogenic index (LC25/NOAEL ratio) of each compound. If the teratogenic index is equal to or greater than 10 then the compound is classified as a teratogen, and if the ratio is less than 10 then the compound is classified as a nonteratogen (Brannen KC et al., Birth Defects Res B Dev Reprod Toxicol 89:66-77, 2010).

Introduction to special issue: Robert Jay Kastenbaum (1932-2013).

PubMed

Fulton, Robert; Klass, Dennis; Doka, Kenneth J; Kastenbaum, Beatrice

The three pieces in this section introduce the Festschrift celebrating the works and influence of Omega: Journal of Death and Dying's founding editor, Robert Kastenbaum. Robert Fulton, an early Associate Editor of the Journal begins with some personal reflections on Kastenbaum. Klass and Doka then describe the nature of the Festschrift. A closing coda by Robert Kastenbaum's wife, Beatrice Kastenbaum, reminds us of the person behind the work.

BIOREMEDIATION OF HAZARDOUS WASTES - RESEARCH, DEVELOPMENT, AND FIELD EVALUATIONS - 1993

EPA Science Inventory

The proceedings of the 1993 Symposium on Bioremediation of Hazardous Wastes, hosted by the Office of Research and Development (ORD) of the EPA in Dallas, Texas The symposium was the sixth annual meeting for the presentation of research conducts (by EPA's Biosystems Technology Dev...

Lessons from Cotton: Research Projects Following Development of a Community-based Genotyping Array

USDA-ARS?s Scientific Manuscript database

High-throughput, cost-effective genotyping arrays provide a standardized resource for plant breeding communities that can be used for a wide range of applications at a suitable pace for integrating pertinent information into breeding programs. Traditionally, crop research communities will target dev...

Implementation of a Flexible Tool for Automated Literature-Mining and Knowledgebase Development (DevToxMine)

EPA Science Inventory

Deriving novel relationships from the scientific literature is an important adjunct to datamining activities for complex datasets in genomics and high-throughput screening activities. Automated text-mining algorithms can be used to extract relevant content from the literature and...

77 FR 34392 - Government-Owned Inventions; Availability for Licensing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-11

... and efficacy against renal and prostate cancer cell lines in vivo. The compound can be efficiently... sperm binding persist after replacement of mouse sperm receptors with human homologs. Dev Cell. 2003 Jul....; 301-435- 4074; [email protected] . Englerin A: A Novel Renal Cancer Therapeutic Isolated...

Harnessing the soil microbiome for increased drought resistance

USDA-ARS?s Scientific Manuscript database

Dr. Manter is a Research Soil Scientist in the Soil Management and Sugar Beet Research Unit (SMSBRU) of the USDA-Agricultural Research Service in Fort Collins, Colorado. His research examines soil biology and plant-microbial interactions aimed at optimizing soil health. Research emphasis is on dev...

DOTD support for UTC project : traffic counting using existing video detection cameras, [research project capsule].

DOT National Transportation Integrated Search

2013-10-01

This study will evaluate the video detection technologies currently adopted by the city : of Baton Rouge, LA, and DOTD with the purpose of establishing design guidelines based : on the detection needs, functionality, and cost. The study will also dev...

The Multilayer Firewall

DTIC Science & Technology

1998-01-01

84. [13] Germano Caronni, Hannes Lubich, Ashar Aziz, Tom Markson, Rich Skrenta, "SKIP - securing the internet," Proceedings of the fifth workshop on...perspective," Open Group Technical Paper DEV-DCE-TP6-1, June 10, 1991. [18] Alan O. Freier, Philip Karlton, Paul C. Kocher, "The SSL Protocol, Version

Robert Wood Johnson Foundation

MedlinePlus

Robert Wood Johnson Foundation Search How We Work Our Focus Areas About RWJF Search Menu How We Work Grants and Grant ... more For Grantees and Grantseekers The Robert Wood Johnson Foundation funds a wide array of programs which ...

Hox genes, digit identities and the theropod/bird transition.

PubMed

Galis, Frietson; Kundrát, Martin; Metz, Johan A J

2005-05-15

Vargas and Fallon (2005. J Exp Zool (Mol Dev Evol) 304B:86-90) propose that Hox gene expression patterns indicate that the most anterior digit in bird wings is homologous to digit 1 rather than to digit 2 in other amniotes. This interpretation is based on the presence of Hoxd13 expression in combination with the absence of Hoxd12 expression in the second digit condensation from which this digit develops (the first condensation is transiently present). This is a pattern that is similar to that in the developing digit 1 of the chicken foot and the mouse hand and foot. They have tested this new hypothesis by analysing Hoxd12 and Hoxd13 expression patterns in two polydactylous chicken mutants, Silkie and talpid2. They conclude that the data support the notion that the most anterior remaining digit of the bird wing is homologous to digit 1 in other amniotes either in a standard phylogenetic sense, or alternatively in a (limited) developmental sense in agreement with the Frameshift Hypothesis of Wagner and Gautier (1999, i.e., that the developmental pathway is homologous to the one that leads to a digit 1 identity in other amniotes, although it occurs in the second instead of the first digit condensation). We argue that the Hoxd12 and Hoxd13 expression patterns found for these and other limb mutants do not allow distinguishing between the hypothesis of Vargas and Fallon (2005. J Exp Zool (Mol Dev Evol) 304B:86-90) and the alternative one, i.e., the most anterior digit in bird wings is homologous to digit 2 in other amniotes, in a phylogenetic or developmental sense. Therefore, at the moment the data on limb mutants does not present a challenge to the hypothesis, based on other developmental data (Holmgren, 1955. Acta Zool 36:243-328; Hinchliffe, 1984. In: Hecht M, Ostrom JH, Viohl G, Wellnhofer P, editors. The beginnings of birds. Eichstätt: Freunde des Jura-Museum. p 141-147; Burke and Feduccia, 1997. Science 278:666-668; Kundrát et al., 2002. J Exp Zool (Mol Dev Evol) 294B:151-159; Larsson and Wagner, 2002. J Exp Zool (Mol Dev Evol) 294B:146-151; Feduccia and Nowicki, 2002. Naturwissenschaften 89:391-393), that the digits of bird wings are homologous to digits 2,3,4 in amniotes. We recommend further testing of the hypothesis by comparing Hoxd expression patterns in different taxa. Copyright 2005 Wiley-Liss, Inc

Conferencias a la Memoria de la Dra. Lydia J. Roberts 1967, 1969-1973 (Conferences in Memory of Dr. Lydia J. Roberts 1967, 1969-1973).

ERIC Educational Resources Information Center

Puerto Rico Univ., Rio Piedras.

This publication includes eleven lectures presented as part of a conference given honoring Dr. Lydia J. Roberts. Seven of the papers are written in the English language and four in Spanish. Most of the papers relate to the topic of nutrition, but a few pay tribute to Dr. Roberts in recognition of her distinguished leadership and teacher of human…

The Effects of Low Level Prenatal Carbon Monoxide on Neocortical Development

DTIC Science & Technology

2010-06-02

amount of NO available, which may have formed free radicals damaging the tissue and resulting in cell death. Treatment with a synthetic cGMP also failed...Watkinson B (36- and 48-month neurobehavioral follow-up of children prenatally exposed to marijuana , cigarettes, and alcohol. J Dev Behav Pediatr

Current status of Tomato chlorotic spot virus in Florida and the Caribbean

USDA-ARS?s Scientific Manuscript database

Damaging outbreaks of Tomato chlorotic spot virus (TCSV), an emerging thrips-vectored tospovirus, and several invasive species of thrips are significantly impacting vegetable and other crops in Florida and the Caribbean. Host and geographic ranges of TCSV are continuing to expand in this region. Dev...

Does WISC-IV Underestimate the Intelligence of Autistic Children?

ERIC Educational Resources Information Center

Nader, Anne-Marie; Courchesne, Valérie; Dawson, Michelle; Soulières, Isabelle

2016-01-01

Wechsler Intelligence Scale for Children (WISC) is widely used to estimate autistic intelligence (Joseph in The neuropsychology of autism. Oxford University Press, Oxford, 2011; Goldstein et al. in "Assessment of autism spectrum disorders." Guilford Press, New York, 2008; Mottron in "J Autism Dev Disord" 34(1):19-27, 2004).…

State of Alaska

Science.gov Websites

Alaska Railroad Alaska Maps Alaska Travel Safety Information Alaska Fish and Game Alaska Facts & Month Services How Do I? Education Health Jobs Safety How Do I? Apply for a Permanent Fund Dividend File Information More Dept. of Commerce, Comm... More Dept. of Labor & Workforce Dev. Safety 511 - Traveler

Toxcast Profiling in a Human Stem Cell Assay for Developmental Toxicity (SOT)

EPA Science Inventory

We correlated the ToxCast library in a metabolic biomarker-based in vitro assay (Stemina devTOXqP) utilizing human embryonic stem (hES) cells (H9 line). This assay identifies the concentration of a chemical that disrupts cellular metabolism in a manner indicative of teratogenic...

Demand for Light Duty Trucks : The Wharton EFA Motor Vehicle Demand Model (Mark II).

DOT National Transportation Integrated Search

1981-01-01

A preliminary model of U.S. light-duty vehicle demand is presented which contains an integrated analysis of automobiles and light trucks (under 10,000 lbs. GVW). The model has been estimated using both cross-section and time-series data, and is a dev...

GESTATIONAL PFOA EXPOSURE OF MICE IS ASSOCIATED WITH ALTERED MAMMARY GLAND DEVELOPMENT IN DAMS AND FEMALE OFFSPRING

EPA Science Inventory

Perfluorooctanoic acid (PFOA), a ubiquitous and persistent synthetic compound, has been detected in human serum. Previous studies in mice linked prenatal PFOA exposure to increased neonatal mortality and decreased pup weights, in a dose responsive manner. To determine whether dev...

Evaluation of barrier treatments on native vegetation in a southern California desert habitat

USDA-ARS?s Scientific Manuscript database

Treating perimeters with residual insecticides to provide protection from mosquito vectors has shown promise. These barrier treatments are typically evaluated in temperate or tropical areas using lush, ambient vegetation as a substrate for the pesticide. However, there is an emerging interest to dev...

Introducing a New International Society of Aeolian Research

USDA-ARS?s Scientific Manuscript database

Aeolian research is long-standing and rapidly growing area of study where scientists of many disciplines meet to investigate the effects of wind on the surface of the Earth and other planetary bodies, such as Mars and Titan. Fields of study in aeolian research cover a broad spectrum ranging from dev...

INITIAL CHARACTERIZATION OF MONOCLONAL ANTIBODIES AGAINST THE FUNGAL HEMOLYSIN STACHYLYSIN FROM STACHYBOTRYS CHARTARUM

EPA Science Inventory

Stachybotrys chartarum is known to produce the hemolysin stachylysin and its detection in human serum has been proposed as a biomarker for exposure to the fungus. In this study we report the initial characterization of monoclonal antibodies (mAbs) against stachylysin and the dev...

EVALUATION OF THE CARBON FOOTPRINT OF INNOVATIVE WATER MAIN REHABILITATION TECHNOLOGIES VS. OPEN CUT METHODS

EPA Science Inventory

A major benefit of trenchless rehabilitation technologies touted by many practitioners when comparing their products with tradition open cut construction methods is lower carbon dioxide (CO₂) emissions. In an attempt to verify these claims, multiple tools have been dev...

Visualizing Mixed Variable-Type Multidimensional Data Using Tree Distances

DTIC Science & Technology

2015-09-01

24 1. The Regression Method .................................................. 25 2. Maximum Deviance Ratio Method... Deviance Change as a Factor of the Amount of Correlation? ................................................... 50 B. A PROPOSED SOLUTION...Splice mapping using d1 ...................... 36 Figure 18. Reduction in 2R analog ( deviance ratio-DevRat) per variable for the Splice data

Net-centric ACT-R-Based Cognitive Architecture with DEVS Unified Process

DTIC Science & Technology

2011-04-01

effort has been spent in analyzing various forms of requirement specifications, viz, state-based, Natural Language based, UML-based, Rule- based, BPMN ...requirement specifications in one of the chosen formats such as BPMN , DoDAF, Natural Language Processing (NLP) based, UML- based, DSL or simply

Automation and Robotics in Construction: Japanese Research and Development

DTIC Science & Technology

1989-10-01

P’rocurei’ment D5epartrnentDivisionEH Nuclear Fac. Engr. p pt. Administration Department Products Dev. Department Housing _jInformation Systems Dept. Sales ... Promotion Division Depart Figure 2. Taisei administrative structure. 13 hgtre . Tisc tehnial erch. Ioramation.Srvc Shimiznfn~~aera Secpotion bil

Self-Perceived Stability and Change in Children's Competence

ERIC Educational Resources Information Center

Vandenplas-Holper, Christiane; Roskam, Isabelle; Fontaine, Anne-Marie

2010-01-01

Using Harter's ("Child Dev" 53(1):87-97, 1982) perceived competence scale, this study integrates several paradigms related to the issues of self-perceived competence, stability or change and attributional theory. It examines how 268 Belgian and Portuguese fifth graders consider their scholastic, social and physical competence at present…

Environmental history impacts gene expression during diapause development in the alfalfa leafcutting bee, Megachile rotundata

USDA-ARS?s Scientific Manuscript database

Our understanding of the mechanisms controlling insect diapause has increased dramatically with the introduction of global gene expression techniques, such as RNAseq. However, little attention has been given to how ecologically relevant field conditions may affect gene expression during diapause dev...

77 FR 44679 - Suntron Corporation, Including On-Site Leased Workers From Manpower, Nesco, TPI and Robert Half...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

... workers leased from NESCO, TPI, and Robert Half working on-site at the Sugarland, Texas location of the... Suntron Corporation, including on-site leased workers from Manpower, NESCO, TPI, and Robert Half, Sugar...

Support Air and Space Expeditionary Forces. Analysis of Combat Support Basing Options

DTIC Science & Technology

2004-01-01

Mahyar A . Amouzegar, Robert S. Tripp, Ronald G. McGarve Edward W Chan C. Robert Roll, Jr. _77 Ap L_ L; Reý PROJECT AIR FORCE - Supporting Air and Space...Expeditionary Forces Analysis of Combat Support Basing Options Mahyar A . Amouzegar Robert S. Tripp Ronald G. McGarvey Edward W. Chan C. Robert Roll...support basing options / Mahyar A . Amouzegar ... [et al. p. cm. "’MG-261." Indudes bibliographical references. ISBN 0-8330-3675-0 (pbk.) 1. Air bases

The Sojourn Time in a Three Node, Acyclic, Jackson Queueing Network.

DTIC Science & Technology

1982-01-27

Effect of Intermediate Storage on Production Lines with Dependent Machines, Robert D. Foley and Petcharat Chansaenwilai 8015 Some Conditions for the...Queues, Robert D. Foley 8105 Reversibility of Production Lines with Dependent Machines, Petcharat Chansaenwilai 1 8106 Queues with Delayed Feedback, Robert

Editorial: Plant organ abscission: from models to crops

USDA-ARS?s Scientific Manuscript database

The shedding of plant organs is a highly coordinated process essential for both vegetative and reproductive development (Addicott, 1982; Sexton and Roberts, 1982; Roberts et al., 2002; Leslie et al., 2007; Roberts and Gonzalez-Carranza, 2007; Estornell et al., 2013). Research with model plants, name...

A Failure in Strategy: America and the Vietnam War 1965-1968

DTIC Science & Technology

2001-04-01

5 Robert S. McNamara, Argument Without End : In Search of Answers to the Vietnam Tragedy (New...McNamara, Robert S. Argument Without End : In Search of Answers to the Vietnam Tragedy . New York: Public Affairs, 1999. McNamara, Robert S. In Retrospect

The Learning Effects of a Multidisciplinary Professional Development Programme

ERIC Educational Resources Information Center

Visser, Talitha Christine; Coenders, Fer G. M.; Pieters, Jules M.; Terlouw, Cees

2013-01-01

Professional development becomes relevant and effective when teachers are actively involved, collaborate, and when it is linked to teachers' daily school practice (Hunzicker in "Prof Dev Educ" 37:177-179, 2011). Preparation of teachers for a curriculum implementation such as the new subject Nature, Life, and Technology can be done…

Strategies for Perceiving Facial Expressions in Adults with Autism Spectrum Disorder

ERIC Educational Resources Information Center

Walsh, Jennifer A.; Vida, Mark D.; Rutherford, M. D.

2014-01-01

Rutherford and McIntosh (J Autism Dev Disord 37:187-196, 2007) demonstrated that individuals with autism spectrum disorder (ASD) are more tolerant than controls of exaggerated schematic facial expressions, suggesting that they may use an alternative strategy when processing emotional expressions. The current study was designed to test this finding…

The Role of Higher Level Adaptive Coding Mechanisms in the Development of Face Recognition

ERIC Educational Resources Information Center

Pimperton, Hannah; Pellicano, Elizabeth; Jeffery, Linda; Rhodes, Gillian

2009-01-01

DevDevelopmental improvements in face identity recognition ability are widely documented, but the source of children's immaturity in face recognition remains unclear. Differences in the way in which children and adults visually represent faces might underlie immaturities in face recognition. Recent evidence of a face identity aftereffect (FIAE),…

Brief Report: Visual Acuity in Children with Autism Spectrum Disorders

ERIC Educational Resources Information Center

Albrecht, Matthew A.; Stuart, Geoffrey W.; Falkmer, Marita; Ordqvist, Anna; Leung, Denise; Foster, Jonathan K.; Falkmer, Torbjorn

2014-01-01

Recently, there has been heightened interest in suggestions of enhanced visual acuity in autism spectrum disorders (ASD) which was sparked by evidence that was later accepted to be methodologically flawed. However, a recent study that claimed children with ASD have enhanced visual acuity (Brosnan et al. in "J Autism Dev Disord"…

CloudStackProjectsNContributions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nielsen, Roy

2017-07-12

Collection of applications and cloud templates. Project currently based on www.packer.io for automation, www.github.com/boxcutter templates and the www.github.com/csd-dev-tools/ClockworkVMs application for wrapping both of the above for easy creation of virtual systems. Will in future also contain cloud templates tuned for various services, applications and purposes.

Human Pluripotent Stem Cell-Based Assay Predicts Developmental Toxicity Potential of ToxCast Chemicals (ACT meeting)

EPA Science Inventory

Worldwide initiatives to screen for toxicity potential among the thousands of chemicals currently in use require inexpensive and high-throughput in vitro models to meet their goals. The devTOX quickPredict platform is an in vitro human pluripotent stem cell-based assay used to as...

Evaluation of 1066 ToxCast Chemicals in a human stem cell assay for developmental toxicity (SOT)

EPA Science Inventory

To increase the diversity of assays used to assess potential developmental toxicity, the ToxCast chemical library was screened in the Stemina devTOX quickPREDICT assay using human embryonic stem (hES) cells. A model for predicting teratogenicity was based on a training set of 23 ...

Evaluation of the Agro-EcoSystem-Watershed (AgES-W)model for estimating nutrient dynamics on a midwest agricultural watershed

USDA-ARS?s Scientific Manuscript database

In order to satisfy the requirements of Conservation Effects Assessment Project (CEAP) Watershed Assessment Study (WAS) Objective 5 (“develop and verify regional watershed models that quantify environmental outcomes of conservation practices in major agricultural regions”), a new watershed model dev...

A Cell Model to Evaluate Chemical Effects on Adult Human Cardiac Progenitor Cell Differentiation and Function

EPA Science Inventory

Adult cardiac stem cells (CSC) and progenitor cells (CPC) represent a population of cells in the heart critical for its regeneration and function over a lifetime. The impact of chemicals on adult human CSC/CPC differentiation and function is unknown. Research was conducted to dev...

Prevention of Post-Radiotherapy Failure in Prostate Cancer by Vitamin D

DTIC Science & Technology

2005-03-01

cur- 55. Mitchell MF, Hittelman WN, Hong WK et al. The natural history cumin , a chemo preventive agent, in patients with high-risk or of cervical...chromosomal DNA loops during oxidative stress . Genes & Dev 13:1553-1560. 16 1999 Chen AY, Choy H and Rothenberg ML. DNA topoisomerase I-targeting drugs as

Factors That Effect Signal Transduction by the Estrogen Receptor.

DTIC Science & Technology

1997-10-01

USA 92, 5386-5390. 14. Gong, J., Ardelt, B., Traganos, F. & Darzynkiewicz, Z . (1994) Cancer Res. 54, 4285-4288. 15. Loda, M., Cukor, B., Tarn, S. W...1997) Genes Dev. 11, 847-862. 36. Adamczewski , J. P., Rossignol, M., Tassan, J. P., Nigg, E. A., Moncollin, V. & Egly, J. M. (1996) EMBO J. 15

COMPARISON OF THE USE OF A PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL AND A CLASSICAL PHARMACOKINETIC MODEL FOR DIOXIN EXPOSURE ASSESSMENTS

EPA Science Inventory

In epidemiological studies, exposure assessments to TCDD, known as a possible human carcinogen, assume mono or biphasic elimination rates. Recent data suggests a dose dependent elimination rate for TCDD. A PBPK model, which uses a body burden dependent elimination rate, was dev...

Joint Light Tactical Vehicle (JLTV)

DTIC Science & Technology

2013-12-01

BY - Base Year DAMIR - Defense Acquisition Management Information Retrieval Dev Est - Development Estimate DoD - Department of Defense DSN - Defense...Production Estimate QR - Quantity Related Qty - Quantity RDT&E - Research, Development , Test, and Evaluation SAR - Selected Acquisition Report Sch - Schedule... Development Estimate) Defense Acquisition Executive (DAE) Approved Acquisition Program Baseline (APB) dated October 23, 2012 Approved APB Defense

Sensory analysis of rainbow trout, oncorhynchus mykiss, fed enriched black soldier fly prepupae, hermetia illucens

USDA-ARS?s Scientific Manuscript database

A growth trial and fillet sensory analysis were conducted to examine the effects of replacing dietary fish meal with black soldier fly (BSF) prepupae, Hermetia illucens, in rainbow trout, Oncorhynchus mykiss. A practical-type trout diet was formulated to contain 45% protein; four test diets were dev...

OPTIMIZATION OF A PULSED LIMESTONE BED REACTOR AT THE ARGO TUNNEL IN IDAHO SPRINGS, COLORADO

EPA Science Inventory

Acid Mine Drainage (AMD) is an unintended consequence of coal and metal mining that adversely affects thousands of miles of streams both in the eastern and western regions of the U.S. A novel AMD treatment process based on limestone based on limestone neutralization has been dev...

Phenazine-1-carboxylic acid influences biofilm development and turnover of rhizobacterial biomass in a soil moisture-dependent manner

USDA-ARS?s Scientific Manuscript database

Rhizobacterial biofilm development influences terrestrial carbon and nitrogen cycles with ramifications for crop and soil health. Phenazine-1-carboxylic acid (PCA) is a redox-active metabolite produced by rhizobacteria in dryland wheat fields of Washington and Oregon, USA. PCA promotes biofilm dev...

The Antiaircraft Journal. Volume 92, Number 5, September-October 1949

DTIC Science & Technology

1949-10-01

philosophical reflections on the subject of po’werand those to whom it should be entrusted. Recall the words of much-studied Machiavelli , than whom...Leavenworth. Kan. Rauch. A. R, Comm. of Basic Phys. Sc.• Res. & Dev. Board, Pentagon. \\Vash. 25. D. C. Rawls . J. W., Jr.. AFF Liaison Off.. Boeing Aircraft

Lessons learned from a one-dimensional water quality model for the Gulf of Mexico

EPA Science Inventory

Hypoxia in the northern Gulf of Mexico has been a major concern for many years. Several water quality models have attempted to describe the link between high nutrient loads from the Mississippi River and hypoxia in the Gulf of Mexico with varied success. Here we describe the dev...

Transformational Leadership and Organizational Change during Agile and DevOps Initiatives

ERIC Educational Resources Information Center

Mayner, Stephen W.

2017-01-01

Organizational change initiatives are more likely to fail than to succeed, especially when the change challenges corporate culture and norms. Researchers have explored factors that contribute to change failure, to include the relationship between leadership behaviors and change success. Peer reviewed studies have yet to examine these variables in…

Literary Translation as a Tool for Critical Language Planning

ERIC Educational Resources Information Center

Mooneeram, Roshni

2013-01-01

This paper argues that Dev Virahsawmy, an author who manipulates literary translation for the purposes of linguistic prestige formation and re-negotiation, is a critical language-policy practitioner, as his work fills an important gap in language planning scholarship. A micro-analysis of the translation of a Shakespearean sonnet into Mauritian…

Improving component interoperability and reusability with the java connection framework (JCF): overview and application to the ages-w environmental model

USDA-ARS?s Scientific Manuscript database

Environmental modeling framework (EMF) design goals are multi-dimensional and often include many aspects of general software framework development. Many functional capabilities offered by current EMFs are closely related to interoperability and reuse aspects. For example, an EMF needs to support dev...

Energy Saving Devices on Gas Furnaces.

DTIC Science & Technology

1980-03-01

AO-A082 0715 JOHNS - MANVILLE SALES CORP DENVER CO RESEARCH AND DEV--ETC FIG 1311 ENERGY SAVING DEVICES ON GAS FURNACES.(U) MAR B0 T E BRISBANE, P B...DEVICES FOR GAS FURNACES THOMAS E. BRISBANE ,o"’ P. B. SHEPHERD JOHNS - MANVILLE SALES CORPORATION RESEARCH & DEVELOPMENT CENTER KEN-CARYL RANCH, DENVER

An Advanced Simulation Framework for Parallel Discrete-Event Simulation

NASA Technical Reports Server (NTRS)

Li, P. P.; Tyrrell, R. Yeung D.; Adhami, N.; Li, T.; Henry, H.

1994-01-01

Discrete-event simulation (DEVS) users have long been faced with a three-way trade-off of balancing execution time, model fidelity, and number of objects simulated. Because of the limits of computer processing power the analyst is often forced to settle for less than desired performances in one or more of these areas.

Managing Irritability and Aggression in Autism Spectrum Disorders in Children and Adolescents

ERIC Educational Resources Information Center

Robb, Adelaide S.

2010-01-01

Children with autism and autism spectrum disorders have a high rate of irritability and aggressive symptoms. In one study up to 20% of children with autism have symptoms of irritability and aggression including aggression, severe tantrums, and deliberate self injurious behavior (Lecavalier [2006] "J. Autism Dev. Disord." 36:1101-1114.). These…

Modulating EGFR Signaling by Targeting the Deacetylase HDAC6-Hsp90 Complex in Breast Tumors

DTIC Science & Technology

2007-06-01

concomitant increase in 4 directed cell migration (15). Analysis of fibroblasts derived from WAVE2 knockout mice 5 demonstrates deficiency in ruffle...Takenawa. 2003. Differential 1 roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for 2 fibroblast cell migration. Dev Cell 5:595

A New GIS-Nitrogen Trading Tool Concept to Minimize Reactive Nitrogen losses to the Environment

USDA-ARS?s Scientific Manuscript database

Nitrogen (N) is an essential element which is needed to maximize agricultural production and sustainability of worldwide agroecosystems. N losses to the environment are impacting water and air quality that has become an environmental concern for the future generations. It has led to the need for dev...

Re-Evaluation of Constant versus Varied Punishers Using Empirically Derived Consequences

ERIC Educational Resources Information Center

Toole, Lisa M.; DeLeon, Iser G.; Kahng, Sung Woo; Ruffin, Geri E.; Pletcher, Carrie A.; Bowman, Lynn G.

2004-01-01

Charlop, Burgio, Iwata, and Ivancic [J. Appl. Behav. Anal. 21 (1988) 89] demonstrated that varied punishment procedures produced greater or more consistent reductions of problem behavior than a constant punishment procedure. More recently, Fisher and colleagues [Res. Dev. Disabil. 15 (1994) 133; J. Appl. Behav. Anal. 27 (1994) 447] developed a…

Determining the static electronic and vibrational energy correlations via two-dimensional electronic-vibrational spectroscopy

DOE PAGES

Dong, Hui; Lewis, Nicholas H. C.; Oliver, Thomas A. A.; ...

2015-05-07

Changes in the electronic structure of pigments in protein environments and of polar molecules in solution inevitably induce a re-adaption of molecular nuclear structure. Both changes of electronic and vibrational energies can be probed with visible or infrared lasers, such as two-dimensional electronic spectroscopy or vibrational spectroscopy. The extent to which the two changes are correlated remains elusive. The recent demonstration of two-dimensional electronic-vibrational (2DEV) spectroscopy potentially enables a direct measurement of this correlation experimentally. However, it has hitherto been unclear how to characterize the correlation from the spectra. In this report, we present a theoretical formalism to demonstrate themore » slope of the nodal line between the excited state absorption and ground state bleach peaks in the spectra as a characterization of the correlation between electronic and vibrational transition energies. In conclusion, we also show the dynamics of the nodal line slope is correlated to the vibrational spectral dynamics. Additionally, we demonstrate the fundamental 2DEV spectral line-shape of a monomer with newly developed response functions« less

Determining the static electronic and vibrational energy correlations via two-dimensional electronic-vibrational spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dong, Hui; Lewis, Nicholas H. C.; Oliver, Thomas A. A.

2015-05-07

Changes in the electronic structure of pigments in protein environments and of polar molecules in solution inevitably induce a re-adaption of molecular nuclear structure. Both changes of electronic and vibrational energies can be probed with visible or infrared lasers, such as two-dimensional electronic spectroscopy or vibrational spectroscopy. The extent to which the two changes are correlated remains elusive. The recent demonstration of two-dimensional electronic-vibrational (2DEV) spectroscopy potentially enables a direct measurement of this correlation experimentally. However, it has hitherto been unclear how to characterize the correlation from the spectra. In this paper, we present a theoretical formalism to demonstrate themore » slope of the nodal line between the excited state absorption and ground state bleach peaks in the spectra as a characterization of the correlation between electronic and vibrational transition energies. We also show the dynamics of the nodal line slope is correlated to the vibrational spectral dynamics. Additionally, we demonstrate the fundamental 2DEV spectral line-shape of a monomer with newly developed response functions.« less

75 FR 49950 - Robert Wayne Mosier, D.O.; Denial of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-16

... DEPARTMENT OF JUSTICE Drug Enforcement Administration Robert Wayne Mosier, D.O.; Denial of... Enforcement Administration, issued an Order to Show Cause to Robert Wayne Mosier, D.O. (Respondent), of... Osteopathic Examiners v. R. Wayne Mosier, D.O., No. 0712-0001 (June 18, 2009). Respondent also held an...

IMMU-22. ADOPTIVE CELL THERAPY AGAINST DIPG USING DEVELOPMENTALLY REGULATED ANTIGENS

PubMed Central

Flores, Catherine; Gil, Jorge; Abraham, Rebecca; Pham, Christina; Wildes, Tyler; Moore, Ginger; Drake, Jeffrey; Dyson, Kyle; Mitchell, Duane

2017-01-01

Abstract INTRODUCTION: Diffuse intrinsic pontine glioma (DIPG) survival has remained static over decades and DIPG is now the main cause of brain tumor-related deaths in children. Immunotherapy has emerged as a treatment modality with the highest curative potential in patients with refractory malignancies. Our group has pioneered an adoptive cell therapy platform employing total tumor RNA pulsed dendritic cells to generate large amounts of polyclonal antigen-specific T cells in both human and murine systems. As DIPGs are embryonal tumors, our objective in this proposal is to identify a set of developmentally regulated antigens that are overexpressed during oncogenesis of DIPG in order to cause immunological rejection of this tumor without the need for tumor tissue. METHODS: We employ RNA-pulsed bone marrow-derived dendritic cells to ex vivo activate tumor-reactive T cells for use in adoptive cell therapy. Here we use either total RNA isolated from tumor tissue, (TTRNA) or developmental antigens (DevAg) RNA isolated from postnatal day 4 murine brain stem. Either TTRNA-T cells or DevAg-T cells were used in adoptive cell therapy against a preclinical model of DIPG. RESULTS: Pediatric brain tumors are bland relative to peripheral tumors in terms of high expression of immunogenic antigens. Since DIPG antigens remain largely uncharacterized, we used total RNA isolated from tumor cells to generate tumor-specific T cells to use for our therapeutic approach to first demonstrate that immune responses can be generated against this tumor. We also successfully generated immunity against DIPG in a preclinical model using DevAg-T cells for adoptive cell therapy. CONCLUSION: The region- and age- specific nature of DIPG suggests that the underlying pathophysiology likely involves dysregulation of a postnatal neurodevelopmental process which occurs in embryonal tumors. Here we leverage this and demonstrate that DIPG can be effectively treated using adoptive cell therapy against overexpressed developmentally regulated antigens.

78 FR 2391 - CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v. Pacific Gas and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-11

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. RP13-436-000] CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v. Pacific Gas and Electric Company... Energy Regulatory Commission (FERC); CAlifornians for Renewable Energy, Inc., Michael E. Boyd, and Robert...

76 FR 7837 - Ryan, Robert M.; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-11

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-6466-000] Ryan, Robert M.; Notice of Filing Take notice that on December 31, 2010, Robert M. Ryan submitted for filing, [email protected] , or call (866) 208-3676 (toll free). For TTY, call (202) 502-8659. Comment Date: 5 p.m...

1. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic Stone Architecture of Winterset, Iowa, Prior to and During the Civil War Period.' Ames, IA: Iowa State University, 1960) Robert R. Harvey, delineator 1960 FLOOR PLAN, ORIGINAL HOUSE ('FIGURE 3-A') - Caleb Clark House, 814 South Eighth Street, Winterset, Madison County, IA

Embracing the Humanistic Vision: Recurrent Themes in Peter Roberts' Recent Writings

ERIC Educational Resources Information Center

Reveley, James

2018-01-01

Running like a leitmotif through Peter Roberts' recently published philosophico-educational writings there is a humanistic thread, which this article picks out. In order to ascertain the quality of this humanism, Roberts is positioned in relation to a pair of extant humanisms: radical and integral. Points of comparability and contrast are…

76 FR 54240 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-31

...: Robert G. Keefe, PhD, Scientific Review Officer, Scientific Review Program, DEA/NIAID/NIH/DHHS, Room 3256... Conference Call). Contact Person: Robert G. Keefe, PhD, Scientific Review Officer, Scientific Review Program... Drive, Bethesda, MD 20817 (Telephone Conference Call). Contact Person: Robert G. Keefe, PhD, Scientific...

DefenseLink.mil - Special Report - Travels With Gates

Science.gov Websites

of Estonia Estonia Defense Secretary Robert M. Gates holds a press conference after the Tallinn High . Sgt. Jerry Morrison Defense Secretary Robert M. Gates holds a press conference after the Tallinn High . Sgt. Jerry Morrison Defense Secretary Robert M. Gates walks with the Prime Minister of Estonia Andrus

Delivering Higher Education to Adults: An Interview with Robert Mendenhall

ERIC Educational Resources Information Center

Finney, Joni E.

2012-01-01

This article presents an interview with Robert Mendenhall, president of Western Governors University, who is the 2012 recipient of the Virginia B. Smith (VBS) Innovative Leadership Award. The annual award recognizes his leadership in redesigning higher education delivery for adult students. In the interview, Robert Mendenhall talks about his work…

Skull Size and Intelligence, and King Robert Bruce's IQ

ERIC Educational Resources Information Center

Deary, Ian J.; Ferguson, Karen J.; Bastin, Mark E.; Barrow, Geoffrey W. S.; Reid, Louise M.; Seckl, Jonathan R.; Wardlaw, Joanna M.; MacLullich, Alasdair M. J.

2007-01-01

An estimate of someone's IQ is a potentially informative personal datum. This study examines the association between external skull measurements and IQ scores, and uses the resulting regression equation to provide an estimate of the IQ of King Robert I of Scotland (Robert Bruce, 1274-1329). Participants were 48 relatively healthy Caucasian men…

Robert Gilmore, a portrait

NASA Astrophysics Data System (ADS)

Solari, Hernán G.

2013-01-01

To present the personality of Bob Gilmore is a formidable task, as his scientific contributions include group theory, laser physics, non-linear dynamics, catastrophe theory, thermodynamics, dynamical systems, quantum theory and more. But even if we succeed in describing his contributions, much of Gilmore's being would be lost. Bob as advisor, Bob as father, Bob as teacher, Bob as scientific communicator reveal as much of Bob Gilmore as his scientific papers and his books. Very much as in the Group Theory so close to him, there is a Robert Gilmore in abstract as well as representations of Robert Gilmore. We will make an attempt to find the "principle of the rule", the abstract level of Robert Gilmore as well as Robert Gilmore, himself, as a representation of the duality science-humanism.

Robert Goddard Young, DC, ND: Searching for a better way

PubMed Central

Brown, Douglas M.

2009-01-01

This biographical study tracks the life of Robert Goddard Young; a member of the Canadian Memorial Chiropractic College’s (CMCC) Class of 1950. The paper begins with an overview of Robert Young’s origins, his childhood and early training, moves to his tour of duty in World War II, followed by his education at CMCC, before converging on the core of this matter; Robert Young’s professional career, which spanned over half a century. Now in his twilight years, the paper ends with a discussion on the substance of Dr. Young’s largely-forgotten contributions. PMID:19714235

75 FR 69444 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-12

... South LaSalle Street, Chicago, Illinois 60690-1414: 1. Robert John Dentel, Victor, Iowa, and Mary P. Howell, Ames, Iowa, individually; and the Robert John Dentel Family (Robert J. Dentel, Patricia A. Dentel... Bank, Corydon, Iowa; First State Bank of Colfax, Colfax, Iowa; Maxwell State Bank, Maxwell, Iowa...

Behavior States and a Half-Full Glass: A Response to Mudford, Hogg, and Roberts.

ERIC Educational Resources Information Center

Arthur, Michael

2000-01-01

In this response to critiques (Mudford, Hogg and Roberts 1997, 1999) of the use of behavior states in research involving individuals with mental retardation, it is argued that the work on behavioral state analysis by Robert D. Guess has contributed to the field at the practical, empirical, and theoretical levels. (Contains references.) (CR)

Robert Curl, Jr. and the Discovery of Fullerenes

Science.gov Websites

produced thousands of variations of the buckyball, including carbon sheets one atom thick and microscopic equilibrium in the carbon vapor that allowed the group to identify a unique, 60-atom configuration of carbon Interview with Robert F. Curl, Jr., nobelprize.org (video) Interview with Robert Curl (video) Buckyballs

Tracing the Building of Robert's Connections in Mathematical Problem Solving: A Sixteen-Year Study

ERIC Educational Resources Information Center

Ahluwalia, Anoop

2011-01-01

This research analyzes how external representations created by a student, Robert, helped him in building mathematical understanding over a sixteen-year period. Robert (also known as Bobby), was an original participant of the Rutgers longitudinal study where students were encouraged to work on problem-solving tasks with minimum intervention (Maher,…

A Model for Modern Nonlinear Noncontiguous Operations: The War in Burma, 1943 to 1945

DTIC Science & Technology

2003-05-01

Approved by: _________________________________________ Monograph Director Robert M. Epstein, Ph.D...Professor and Director Robert H. Berlin, Ph.D. Academic Affairs, School of Advanced Military Studies _________________________________________ Director...I would like to thank Dr Robert Epstein for his guidance during the production of this monograph. My thanks also go to my Wife, Aly, for her patience

3. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic Stone Architecture of Winterset, Iowa, Prior to and During the Civil War Period.' Ames, IA: Iowa State University, 1960.) Robert R. Harvey, delineator 1960 FLOOR PLAN, ORIGINAL HOUSE PLUS SMOKEHOUSE ADDITION ('FIGURE 3-C') - Caleb Clark House, 814 South Eighth Street, Winterset, Madison County, IA

2. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Photocopy of measured drawing (from: Harvey, Robert R. 'Historic Stone Architecture of Winterset, Iowa, Prior to and During the Civil War Period.' Ames, IA: Iowa State University, 1960.) Robert R. Harvey, delineator 1960 FLOOR PLAN, ORIGINAL HOUSE PLUS WELLHOUSE ADDITION ('FIGURE 3-B') - Caleb Clark House, 814 South Eighth Street, Winterset, Madison County, IA

76 FR 20033 - Robert Charles Ley, D.O. ; Dismissal of Proceeding

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-11

... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 10-8] Robert Charles Ley, D.O... Charles Ley, D.O. (Respondent), of Kihei, Hawaii. Order to Show Cause at 1. The Order, which also sought... Suspension of Registration issued to Robert Charles Ley, D.O, be, and it hereby is, dismissed. Dated: April 1...

75 FR 57846 - Airworthiness Directives; Robert E. Rust, Jr. Model DeHavilland DH.C1 Chipmunk 21, DH.C1 Chipmunk...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-23

... Airworthiness Directives; Robert E. Rust, Jr. Model DeHavilland DH.C1 Chipmunk 21, DH.C1 Chipmunk 22, and DH.C1... installation, with replacement as necessary for Robert E. Rust, Jr. Model DeHavilland DH.C1 Chipmunk 21, DH.C1...

Structural Stability of a Joined-Wing Sensorcraft

DTIC Science & Technology

2007-06-01

Robert A. Canfield (Chairman) Date //SIGNED// Dr. Donald Kunz (Member) Date //SIGNED// Maj. Eric...to my thesis advisor, Dr. Robert Canfield, for his guidance and instruction throughout this thesis. His patience and availability were immensely...concept and provide detailed information with regards to the divergence of the linear and nonlinear analysis results of the SensorCraft. Roberts

Engineer Support to the Brigade Combat Team

DTIC Science & Technology

2010-05-20

Director, Robert F. Baumann, Ph.D. Graduate Degree Programs Disclaimer: Opinions, conclusions, and recommendations expressed or implied...companies, now totaling over seven thousand 12 Robert R. Ploger, MG, USA, Vietnam Studies: U.S...mission was complete they would be reallocated to other assets who needed them. The commander of the 18th Engineer Brigade, Major General Robert P

76 FR 51047 - North Dakota; Amendment No. 10 to Notice of a Major Disaster Declaration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-17

... authority of the Robert T. Stafford Disaster Relief and Emergency Assistance Act, 42 U.S.C. 5121 et seq... arrangements are warranted regarding Federal funds provided under the Robert T. Stafford Disaster Relief and... Assistance costs eligible for such adjustments under the law. The Robert T. Stafford Disaster Relief and...

76 FR 77728 - Process for a Designated Contract Market or Swap Execution Facility To Make a Swap Available To...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-14

..., 2011 at 9; Letter from Robert Pickel and Kenneth Bentsen, International Swaps and Derivatives..., dated Apr. 5, 2011 at 19; Letter from Robert Pickel and Kenneth Bentsen, International Swaps and... LLP, on behalf of certain dealers, dated Apr. 5, 2011 at 19; Letter from Robert Pickel and Kenneth...

The Relationship between Sensory Sensitivity and Autistic Traits in the General Population

ERIC Educational Resources Information Center

Robertson, Ashley E.; Simmons, David R.

2013-01-01

Individuals with Autism Spectrum Disorders (ASDs) tend to have sensory processing difficulties (Baranek et al. in J Child Psychol Psychiatry 47:591-601, 2006). These difficulties include over- and under-responsiveness to sensory stimuli, and problems modulating sensory input (Ben-Sasson et al. in J Autism Dev Disorders 39:1-11, 2009). As those…

12om Limited Objective Experiment #2: Final Results Summary and Recommendations

DTIC Science & Technology

2014-03-31

Acronym Definition ARP CD CF CFD CG CIM COA CONOPS CSE Dev DFATD DP DRDC FGS Gov HREC IDP KR LOE LOC MA MARS NASA TLX NGO OP OPP Ops ROC SA...weight Ratings (OPP Support) Ratings (IP) Ratings (CU) Ratings (CS) Ratings (Usability) Ratings (Training T/E) Ratings (Use T/E) NASA TLX Mental demand

OSTI.GOV | OSTI, US Dept of Energy Office of Scientific and Technical

Science.gov Websites

Information Skip to main content ☰ Submit Research Results Search Tools Public Access Policy Data Services & Dev Tools About FAQs News Sign In Create Account Sign In Create Account Department Information Search terms: Advanced search options Advanced Search OptionsAdvanced Search queries use a

Customized Resources | OSTI, US Dept of Energy Office of Scientific and

Science.gov Websites

Technical Information skip to main content Sign In Create Account OSTI.GOV title logo U.S . Department of Energy Office of Scientific and Technical Information Search terms: Advanced search options Tools Public Access Policy Data Services & Dev Tools About FAQs News Sign In Create Account This

DOE Collections | OSTI, US Dept of Energy Office of Scientific and

Science.gov Websites

Technical Information skip to main content Sign In Create Account OSTI.GOV title logo U.S . Department of Energy Office of Scientific and Technical Information Search terms: Advanced search options Tools Public Access Policy Data Services & Dev Tools About FAQs News Sign In Create Account This

Contact Us | OSTI, US Dept of Energy Office of Scientific and Technical

Science.gov Websites

Information skip to main content Sign In Create Account OSTI.GOV title logo U.S. Department of Energy Office of Scientific and Technical Information Search terms: Advanced search options Advanced Tools Public Access Policy Data Services & Dev Tools About FAQs News Sign In Create Account Contact

The frequency of channel-forming discharges in a tributary of Upper Big Walnut Creek, Ohio

USDA-ARS?s Scientific Manuscript database

The goal of this study was to determine the frequency and magnitude of annual out-of-bank discharges in Sugar Creek, a tributary of the Upper Big Walnut Creek, in Ohio. To address this goal: a stream geomorphology study was conducted; measured discharge data at a downstream location were used to dev...

Supplemental Grounding of Extended EMP Collectors.

DTIC Science & Technology

1982-01-31

G52AAXEX40602 H2590D as Contract DNA 001-80-C-0294. The program was monitored by Major Blair Williams, RAEE . The work described in this report was...ATTN: RAEE ATTN: DPOPM-COM-W-D ATTN RAAE ATTN: NATA Deputy Chief of Staff for Rsch Dev & Acq 4 cy ATTN: TITL ATTN: DAMA-CSS-N Defense Tech Info Ctr

DEVELOPMENT, CALIBRATION AND APPLICATION OF A CONTAINMENT TRANSPORT AND FATE MASS BALANCE MODEL IN LAKE MICHIGAN, LM2

EPA Science Inventory

The Lake Michigan Mass Balance Project (LMMBP) was initiated to support the development of a Lake Wide Management Plan (LaMP) for Lake Michigan. As one of the models in the LMMBP modeling framework, the Level 2 Lake Michigan containment transport and fate (LM2) model has been dev...

Perceived Social Competence and Loneliness among Young Children with ASD: Child, Parent and Teacher Reports

ERIC Educational Resources Information Center

Zeedyk, Sasha M.; Cohen, Shana R.; Eisenhower, Abbey; Blacher, Jan

2016-01-01

Perceived loneliness and social competence were assessed for 127 children with ASD without comorbid ID, 4-7 years old, through child self-report. Using an abbreviated version of the "Loneliness and Social Dissatisfaction Questionnaire" (LSDQ; Cassidy and Asher in Child Dev 63:250-365, 1992), the majority of children reported friendships,…

INTERIM REPORT, DEVELOP A SAMPLING STRATEGY: PREPARE TO IMPLEMENT A COHORT STUDY OF CHILDREN'S ENVIRONMENTAL HEALTH

EPA Science Inventory

Overview

The goal of the National Children's Study (NCS) is to collect information on environmental and

social factors in the lives of children, starting before birth and continuing until age 21, to inform

researchers about their effects on the health and dev...

Whole genome sequencing of the Braconid parasitoid wasp Fopius arisanus, an important biocontrol agent of pest Tepritid fruit flies

USDA-ARS?s Scientific Manuscript database

The braconid wasp Fopius arisanus (Sonan) is an important biological control agent of tropical and subtropical pest fruit flies including two important global pests, the Mediterranean fruit fly (Ceratitis capitata), and the oriental fruit fly (Bactrocera dorsalis}). The goal of this study was to dev...

Spectroscopic Characterization of HAN-Based Liquid Gun Propellants and Nitrate Salt Solutions

DTIC Science & Technology

1989-01-15

cables (0.040-in. o.d. x 2.5 ft) consisting of an Inconel sheath containing two nickel / chromium/iron wires that were insulated from each other ser...Subramanlam and M. A. McHugh , I&EC Pruc. Des. Dev. 25, 1 therefore attributed to thermal line broadening instead (1986). of to changes in the equilibrium

Toxcast and the Use of Human Relevant In Vitro Exposures: Incorporating High-Throughput Exposure and Toxicity Testing Data for 21st Century Risk Assessments (British Toxicological Society Annual Congress)

EPA Science Inventory

The path for incorporating new approach methods and technologies into quantitative chemical risk assessment poses a diverse set of scientific challenges. These challenges include sufficient coverage of toxicological mechanisms to meaningfully interpret negative test results, dev...

20180312 - Profiling the ToxCast library with a pluripotent human (H9) embryonic stem cell assay (SOT)

EPA Science Inventory

The Stemina devTOX quickPredict platform (STM) is a human pluripotent H9 stem cell-based assay that predicts developmental toxicants. Using the STM model, we screened 1065 ToxCast chemicals and entered the data into the ToxCast data analysis pipeline. Model performance was 83.3% ...

The Autism-Spectrum Quotient and Visual Search: Shallow and Deep Autistic Endophenotypes

ERIC Educational Resources Information Center

Gregory, B. L.; Plaisted-Grant, K. C.

2016-01-01

A high Autism-Spectrum Quotient (AQ) score (Baron-Cohen et al. in "J Autism Dev Disord" 31(1):5-17, 2001) is increasingly used as a proxy in empirical studies of perceptual mechanisms in autism. Several investigations have assessed perception in non-autistic people measured for AQ, claiming the same relationship exists between…

Serving the Needs of Gifted Learners around the Globe: An Interview with Julia Link Roberts

ERIC Educational Resources Information Center

Henshon, Suzanna E.

2018-01-01

Julia Link Roberts is the Mahurin Professor of Gifted Studies at Western Kentucky University (WKU) and the executive director of The Center for Gifted Studies and The Gatton Academy of Mathematics and Science in Kentucky. Dr. Roberts is the president of the World Council for Gifted and Talented Children; current past-president of The Association…

78 FR 22284 - Notice of Intent To Repatriate a Cultural Item: U.S. Department of the Interior, Bureau of Indian...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-15

... Affairs, Washington, DC, and the Robert S. Peabody Museum of Archaeology, Phillips Academy, Andover, MA..., Washington, DC, and in the physical custody of the Robert S. Peabody Museum of Archaeology, Phillips Academy... Archaeology, Phillips Academy, Andover, MA Officials of the Bureau of Indian Affairs and the Robert S. Peabody...

The Marine Corps Martial Arts Program: Sustaining the Transformation

DTIC Science & Technology

2002-04-01

Approved: _______________ Date: _______________ Mentor: Colonel Robert P. Wagner, USMC Approved: _______________ Date: _______________ REPORT... Robert Debs Heinl Jr., USMC (Ret.), Soldiers of the Sea (Annapolis, MD: United States Naval Institute, 1962), 603. 7 constituency of the force, as well...changes over decades, the Marine Corps has shown the ability to adapt its training to meet those conditions. As Colonel Robert Wagner noted, over time

Development of Amphibious Doctrine

DTIC Science & Technology

2010-06-11

Graduate Degree Programs Robert F. Baumann, Ph.D. The opinions and conclusions expressed herein are those of the student author and do not...battalion composed of six companies of Marines, its commander, Lieutenant Colonel Robert W. Huntington, finally received the mission of securing an...42,000 men. The participants included the Commanding Officer, Marine Corps Schools, Colonel Robert Dunlap, as well as the students and instructors

Military Governance and War Termination

DTIC Science & Technology

2011-05-19

Military Studies ___________________________________ Director, Robert F. Baumann, Ph.D. Graduate Degree Programs Disclaimer: Opinions...77 J. Boone Barthlomees, “Theory of Victory,” Parameters XXVII, no. 2 (Summer 2008), 27. 78 Robert Mandel, “Reassessing Victory in Warfare." Armed...political goals, but not, for whatever reasons, reaching total political success.”80 A critical point presented by Dr. Robert Mandel is that victory is

Robert Klopstock and Franz Kafka--the friends from Tatranské Matliare (the High Tatras).

PubMed

Mydlík, M; Derzsiová, K

2007-01-01

The paper summarises the accessible literature on the life and work of well-known American lung surgeon, Professor Dr. Med. Robert Klopstock, who was in the years 1920-1924 a friend Franz Kafka. Professor Klopstock was of Hungarian origin and he got acquainted with Franz Kafka at the end of the year 1920 in Tatranské Matliare (The High Tatras). They were both patients treated for lung tuberculosis. They became close friends and their mutual correspondence shows their real friendship. Robert Klopstock was present at Franz Kafka's death-bed on June 3, 1924 in Kierling, near Klosterneuburg, not far from Vienna. Robert Klopstock studied at Medical Faculties of the Universities in Budapest, Prague, Kiel and Berlin. After his graduation in 1933 in Berlin, he worked as a lung surgeon at various surgical clinics and departments in Budapest and Berlin. In 1936 Robert Klopstock together with his wife visited the High Tatras and Tatranské Matliare. In 1937 Robert Klopstock with his wife Gizela, a writer and a translator, who translated the first chapters of Franz Kafka's novel "Trial" into Hungarian language, went to United States of America. During his stay in U.S.A. Dr. Med. Robert Klopstock was very active as a lung surgeon and a scientist. He published 64 specialized scientific papers, mostly in American medical journals. He became Professor of Lung Surgery at Downstate Medical Centre in New York-Brooklyn. He died on June 15, 1972 in New York.

A Conversation with Robert F. Christy Part I

NASA Astrophysics Data System (ADS)

Lippincott, Sara

2006-09-01

Robert F. Christy, Institute Professor of Theoretical Physics Emeritus at Caltech, recalls his childhood in British Columbia; his undergraduate years at the University of British Columbia; his graduate work with J. Robert Oppenheimer at Berkeley; and his work on the Manhattan Project, first with Enrico Fermi at the Metallurgical Laboratory of the University of Chicago and then as a member of the Theoretical Division at Los Alamos.

Studying Materials Using Acoustic Waves

DTIC Science & Technology

1988-03-01

Biological Materials." J. Acoust. Soc. Am. 7£, 636 (1981). Robert E. Apfel "Acoustic Cavitation : A Possible Consequence of Biomedical Uses of Ultrasound ...Soc. Am. 19_, 148 (1986). Robert E. Apfel "Possibility of Micro- Cavitation from Diagnostic Ultrasound ." IEEE Trans. on Ultrasonics...Madanshetty and R.A. Roy "Thresholds for Acoustic Cavitation Produced in Water by Pulsed Ultrasound ." Ultrasonics (UK) - in Press. Robert E. Apfel

Regulation of ATM-Dependent DNA Damage Responses in Breast Cancer by the RhoGEF Net1

DTIC Science & Technology

2014-04-01

1998) Science 279: 509-514. 12. Harper JW, et al., (2007) The DNA Damage Response: Ten years after. Mol. Cell 28; 739-745. 13. Hill R, et al., (2010...RhoGTPases: Biochemistry and Biology. Annu. Rev. Cell Dev. Biol. 21:247-269. 17. Khanna KK, et al., (2001) ATM, a central controller of cellular

Child Autism Spectrum Disorder Traits and Parenting Stress: The Utility of Using a Physiological Measure of Parental Stress

ERIC Educational Resources Information Center

Factor, Reina S.; Swain, Deanna M.; Scarpa, Angela

2018-01-01

Caregivers of children with autism spectrum disorder (ASD) report greater stress due to unique parenting demands (e.g.; Estes et al. in "Brain Dev" 35(2):133-138, 2013). Stress is often studied through self-report and has not been extensively studied using physiological measures. This study compared parenting stress in mothers of…

The Glasgow Sensory Questionnaire: Validation of a French Language Version and Refinement of Sensory Profiles of People with High Autism-Spectrum Quotient

ERIC Educational Resources Information Center

Sapey-Triomphe, Laurie-Anne; Moulin, Annie; Sonié, Sandrine; Schmitz, Christina

2018-01-01

Sensory sensitivity peculiarities represent an important characteristic of Autism Spectrum Disorders (ASD). We first validated a French language version of the Glasgow Sensory Questionnaire (GSQ) (Robertson and Simmons in "J Autism Dev Disord" 43(4):775-784, 2013). The GSQ score was strongly positively correlated with the Autism-Spectrum…

Running Gaussian16 Software Jobs on the Peregrine System | High-Performance

Science.gov Websites

, parallel setup is taken care of automatically based on settings in the PBS script example below. Previous filesystem called /dev/shm. This scratch space is set automatically by the example script below. The Gaussian system. An example script for batch submission is given below. #!/bin/bash #PBS -l nodes=2 #PBS -l

Coordination of BRCA1/BARD1- and MRE11/RAD50/NBS1-dependent DNA Transactions in Breast Tumor Suppression

DTIC Science & Technology

2011-07-01

prevent toxic chromosome rearrangements. Because MMEJ is active throughout the cell cycle, it could pro- mote translocations when any of the following...in preserving genomic stability. Genes Dev. 24:1680–94 66. Keelagher RE, Cotton VE, Goldman AS, Borts RH. 2011. Separable roles for exonuclease I in

Coordination of BRCA1/BARD1- and MRE11/RAD50/NBS1-Dependent DNA Transactions in Breast Tumor Suppression

DTIC Science & Technology

2011-07-01

active throughout the cell cycle, it could pro- mote translocations when any of the following aberrancies occur: (a) inhibition of C-NHEJ; (b...in preserving genomic stability. Genes Dev. 24:1680–94 66. Keelagher RE, Cotton VE, Goldman AS, Borts RH. 2011. Separable roles for exonuclease I in

Camera-Based Microswitch Technology to Monitor Mouth, Eyebrow, and Eyelid Responses of Children with Profound Multiple Disabilities

ERIC Educational Resources Information Center

Lancioni, Giulio E.; Bellini, Domenico; Oliva, Doretta; Singh, Nirbhay N.; O'Reilly, Mark F.; Lang, Russell; Didden, Robert

2011-01-01

A camera-based microswitch technology was recently used to successfully monitor small eyelid and mouth responses of two adults with profound multiple disabilities (Lancioni et al., Res Dev Disab 31:1509-1514, 2010a). This technology, in contrast with the traditional optic microswitches used for those responses, did not require support frames on…

Targeting Heterogeneity and Comorbidity in Children with Autism Spectrum Disorder through the Resilience Builder Group Therapy Program

ERIC Educational Resources Information Center

Habayeb, Serene; Rich, Brendan; Alvord, Mary K.

2017-01-01

Background: Children with autism spectrum disorders (ASD) often carry co-morbid diagnoses and present with impairing heterogeneous symptomatology (Leyfer et al. in "J Autism Dev Disord" 36(7): 849-861, 2006. doi:10.1007/s10803-006-0123-0). However, research from controlled laboratory settings often fails to examine the vast number of…

Brief Report: Assessment of Intervention Effects on in Vivo Peer Interactions in Adolescents with Autism Spectrum Disorder (ASD)

ERIC Educational Resources Information Center

Dolan, Bridget K.; Van Hecke, Amy V.; Carson, Audrey M.; Karst, Jeffrey S.; Stevens, Sheryl; Schohl, Kirsten A.; Potts, Stephanie; Kahne, Jenna; Linneman, Nina; Remmel, Rheanna; Hummel, Emily

2016-01-01

This study aimed to evaluate the effectiveness of a randomized controlled trial of a social skills intervention, the Program for the Education and Enrichment of Relational Skills (PEERS: Laugeson et al. in "J Autism Dev Disord" 39(4): 596-606, 2009), by coding digitally recorded social interactions between adolescent participants with…

Evaluation of the ADOS Revised Algorithm: The Applicability in 558 Dutch Children and Adolescents

ERIC Educational Resources Information Center

de Bildt, Annelies; Sytema, Sjoerd; van Lang, Natasja D. J.; Minderaa, Ruud B.; van Engeland, Herman; de Jonge, Maretha V.

2009-01-01

The revised ADOS algorithms, proposed by Gotham et al. (J Autism Dev Disord 37:613-627, 2007), were investigated in an independent sample of 558 Dutch children (modules 1, 2 and 3). The revised algorithms lead to better balanced sensitivity and specificity for modules 2 and 3, without losing efficiency of the classification. Including the…

A Parent-Mediated Intervention that Targets Responsive Parental Behaviors Increases Attachment Behaviors in Children with ASD: Results from a Randomized Clinical Trial

ERIC Educational Resources Information Center

Siller, Michael; Swanson, Meghan; Gerber, Alan; Hutman, Ted; Sigman, Marian

2014-01-01

The current study is a randomized clinical trial evaluating the efficacy of Focused Playtime Intervention (FPI) in a sample of 70 children with Autism Spectrum Disorder. This parent-mediated intervention has previously been shown to significantly increase responsive parental communication (Siller et al. in "J Autism Dev Disord"…

Parents' Translations of Child Gesture Facilitate Word Learning in Children with Autism, Down Syndrome and Typical Development

ERIC Educational Resources Information Center

Dimitrova, Nevena; Özçaliskan, Seyda; Adamson, Lauren B.

2016-01-01

Typically-developing (TD) children frequently refer to objects uniquely in gesture. Parents translate these gestures into words, facilitating children's acquisition of these words (Goldin-Meadow et al. in "Dev Sci" 10(6):778-785, 2007). We ask whether this pattern holds for children with autism (AU) and with Down syndrome (DS) who show…

Student Perceptions of Effective Instruction and the Development of Critical Thinking: A Replication and Extension

ERIC Educational Resources Information Center

Loes, Chad N.; Salisbury, Mark H.; Pascarella, Ernest T.

2015-01-01

This study utilized data from the Wabash National Study of Liberal Arts Education to test the robustness of research conducted by Pascarella et al. ("J Coll Stud Dev" 37:7-19, 1996) that explored the relationship between student perceptions of exposure to organized and clear instruction and growth in critical thinking skills among…

Investigating Young Children's Perceptions of Body Size and Healthy Habits

ERIC Educational Resources Information Center

Xu, Tingting; Nerren, Jannah S.

2017-01-01

Attitudes and biases toward body size perceived as fat and body size perceived as thin are present in young children (Cramer and Steinwert in "J Appl Dev Psychol" 19(3):429-451, 1998; Worobey and Worobey in "Body Image" 11:171-174, 2014). However, the information children have regarding body size and ways to modify body size…

Mechanism of Developmental Change in the PLAY Project Home Consultation Program: Evidence from a Randomized Control Trial

ERIC Educational Resources Information Center

Mahoney, Gerald; Solomon, Richard

2016-01-01

This investigation is a secondary analysis of data from a randomized control trial of the PLAY Home Consultation Intervention Program which was conducted with 112 preschool children with Autism Spectrum Disorders and their parents (Solomon et al. in "J Dev Behav Pediatr" 35:475-485, 2014). Subjects were randomly assigned to either a…

Standardized ADOS Scores: Measuring Severity of Autism Spectrum Disorders in a Dutch Sample

ERIC Educational Resources Information Center

de Bildt, Annelies; Oosterling, Iris J.; van Lang, Natasja D. J.; Sytema, Sjoerd; Minderaa, Ruud B.; van Engeland, Herman; Roos, Sascha; Buitelaar, Jan K.; van der Gaag, Rutger-Jan; de Jonge, Maretha V.

2011-01-01

The validity of the calibrated severity scores on the ADOS as reported by Gotham et al. (J Autism Dev Disord 39: 693-705, "2009"), was investigated in an independent sample of 1248 Dutch children with 1455 ADOS administrations (modules 1, 2 and 3). The greater comparability between ADOS administrations at different times, ages and in…

Performance Analysis of AeroRP with Ground Station Advertisements

DTIC Science & Technology

2012-03-12

results showed that AeroRP outperforms the traditional MANET routing protocols in terms of throughput and packet delivery ra - tio (PDR) [5, 6]. AeroRP...and waiting for the source to re- send the packet increases the end-to-end delay. The AeroNP corruption indicator and HEC -CRC (header error check...Dev ID | NP HEC CRC-16 | +-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+-+ \\ \\ / AeroTP Payload

Development of C++ Application Program for Solving Quadratic Equation in Elementary School in Nigeria

ERIC Educational Resources Information Center

Bandele, Samuel Oye; Adekunle, Adeyemi Suraju

2015-01-01

The study was conducted to design, develop and test a c++ application program CAP-QUAD for solving quadratic equation in elementary school in Nigeria. The package was developed in c++ using object-oriented programming language, other computer program that were also utilized during the development process is DevC++ compiler, it was used for…

The Association between Teachers' Child-Centered Beliefs and Children's Academic Achievement: The Indirect Effect of Children's Behavioral Self-Regulation

ERIC Educational Resources Information Center

Hur, Eunhye; Buettner, Cynthia K.; Jeon, Lieny

2015-01-01

Background: Recent studies have suggested that teachers' psychological attributes can be an indicator of teacher quality (Rimm-Kaufman and Hamre in "Dev Psychol" 45(4):958-972. doi: 10.1037/a0015861 , 2010), and teachers' child-centered beliefs have been associated with children's academic achievement (Burchinal and Cryer in "Early…

In the eyes of the beholder: Understanding subtypes of social withdrawal among young Chinese children.

PubMed

Cheah, Charissa S L; Xu, Yiyuan

2015-06-01

In this commentary on Ding et al. (Brit. J. Dev. Psychol., 2015; 33, 159-173), we focus on the following: (1) the authors' use of vignettes portraying various prototypes of withdrawn children and (2) the cultural interpretation of their findings. We end with some suggestions for future research. © 2015 The British Psychological Society.

Army Amateur Radio System: 1925-1941

DTIC Science & Technology

2010-05-21

1948 Captain Robert L. Gabardy selected the use of the acronym MARS, the Roman god of war, as a fitting name for the post-World War II rebirth of the...3 Robert L. Gabardy , telephonic interview by author, January 26, 2010. In approaching its mission as an auxiliary, MARS can examine...accessed January 25, 2010). Interviews Gabardy , Robert L., interview by author, January 26, 2010. Hart, George, interview by author, January 27

Games for Health, 2011

DTIC Science & Technology

2011-06-01

The Games for Health Project, an effort organized by Digitalmill, Inc. with funding from the Robert Wood Johnson Foundation held its 7th Annual Games...features, media and design patterns associated with videogames. Some of this work is already being done by academia and grantees of Robert Wood ...for game-based interventions really exists (or doesn’t) that can be beneficial to future funding efforts by organizations such as Robert Wood Johnson

Looking Forward: Texas and Its Elderly. Highlights of the Robert Lee Sutherland Seminar (4th, Austin, Texas, May 12, 1984).

ERIC Educational Resources Information Center

Coleman, Marion Tolbert, Ed.; And Others

This document presents the program agenda and highlights from the one-day Robert Lee Sutherland Seminar held to examine the current status and the future of the elderly population of Texas. Included is the speech, "The Longevity Revolution" by Robert N. Butler, in which is discussed the gain in life expectancy, the feminization of aging,…

High Frontier, The Journal for Space & Missile Professionals. Volume 4, Number 4

DTIC Science & Technology

2008-08-01

46 Next Issue: Space Protection High Frontier Introduction General C . Robert Kehler Commander, Air Force Space Command “ The ... the Air Force and General C . Robert “Bob” Kehler (BS, Education, Pennsylvania State University; MS, Public Administra- tion, University of Oklahoma...depth interview with Dr. F. Robert Naka, former deputy director of the NRO (1969- 1972 ) and former chief scientist of the Air Force (1975-1978

The Effect of Advanced Education on the Retention and Promotion of Army Officers

DTIC Science & Technology

2007-03-01

2 Ronal G.Ehrenberg, Robert S.Smith, Modern Labor Economics , Theory and Public Policy, (New York: Pearson Education, Inc, 2006...Ehrenberg and Robert S. Smith, Modern Labor Economics , 9th ed. (New York: Pearson Education, Inc, 2006). 30 G S Becker, Human Capital: A Theoretical...their jobs. As a 32 Ronald G. Ehrenberg and Robert S. Smith, Modern Labor Economics , 9th ed. (New

75 FR 32093 - Revision of Restricted Area R-2504; Camp Roberts, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-07

...-0557; Airspace Docket No. 10-AWP-6] RIN 2120-AA66 Revision of Restricted Area R-2504; Camp Roberts, CA... Restricted Area R-2504, Camp Roberts, CA, by subdividing the area of R-2504 to create R-2504A and R-2504B. Together, R-2504A and R-2504B will occupy the same lateral and vertical dimensions of the existing R-2504...

Dr. Robert Goddard

NASA Image and Video Library

2010-01-04

Dr. Robert Goddard and colleagues at Roswell, New Mexico. Successful test of May 19, 1937. Dr. Robert Goddard is holding the cap and pilot parachute, parts of the successful operation. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

The Evolution of Marine Artillery: A History of Versatility and Relevance

DTIC Science & Technology

2012-03-28

Colonel Robert W. Huntington who commanded it, was formed. This included one artillery company manning four 3-inch rapid fire guns.7 The Marine...Major Robert H. Dunlap. That same battalion, which would soon be the foundation for the 10th Marine Regiment, distinguished itself in combat at La...force capable of counter-guerilla operations. Of note, Colonel Robert H. Dunlap commanded the regiment. 19 Officers during this period were versatile

Sustaining Equipment and the Rapid Acquisition Process: The Forgotten Phase

DTIC Science & Technology

2012-02-24

Operation of the Defense Acquisition System,” December 8, 2008. 7 Rasch , Robert. A, Jr. Lessons Learned from Rapid Acquisition: Better, Faster, Cheaper...Life Cycle Management Responsibilities,” Defense AR Journal, 17.2 (April 2010): 183. 37 Robert A. Rasch , Lessons Learned from Rapid Acquisition: Better...Accountability Office (GAO) Report, Subject: Rapid Acquisition of Mine Resistant Protected Vehicles, July 15, 2008, 4. 39 Ibid. 40 Ibid. 41 Robert A. Rasch

The Operational Air National Guard: Relationship Changes and Policy Implications

DTIC Science & Technology

2015-02-13

Operational ANG” after U.S. withdrawal from Iraq and Afghanistan. Secretary of Defense Robert Gates’ 19 January 2007 memo, “Utilization of the Total...the RCs provide strategic depth and are available to transition to operational roles as needed. 25 Secretary of Defense, Robert M. Gates, 19...An Illustrated History of America’s Citizen-Soldiers. Dulles, VA: Potomac Books Inc., 2007. Gates, Robert M., U.S. Secretary of Defense. To

An Extensive X-ray Computed Tomography Evaluation of a Fully Penetrated Encapsulated SiC MMC Ballistic Panel

DTIC Science & Technology

2009-04-01

An Extensive X-ray Computed Tomography Evaluation of a Fully Penetrated Encapsulated SiC MMC Ballistic Panel by William H. Green and Robert H...Panel William H. Green and Robert H. Carter Weapons and Materials Research Directorate, ARL...PROGRAM ELEMENT NUMBER 2182040 6. AUTHOR(S) William H. Green and Robert H. Carter 5d. PROJECT NUMBER AH80 5e. TASK NUMBER 5f. WORK UNIT

Building Component Maintenance and Repair Data Base: Heating, Ventilating, and Air Conditioning (HVAC) Systems

DTIC Science & Technology

1991-05-01

Building Component Maintenance and Repair Data Base: Heating, Ventilating, and Air Conditioning (HVAC) Systems by Edgar S. Neely Robert D. Neathammer...Repair Data Base: Heating, Ventilating, and Air Conditioning (HVAC) Systems RDTE dated 1980EIMB 1984 - 1989 6. AUTHOR(S) Edgar S. Neely, Robert D...Laboratory (USACERL). The Principal Investigators were Dr. Edgar Neely and Mr. Robert Neathammer (USACERL-FS). The primary contractor for much of the

Defense Planning for the 1990s and the Changing International Environment

DTIC Science & Technology

1984-01-01

Atlantic Alliance: Looking Ahead ................. 87 Dr. Robert L. Pfaltzgraff, Jr. The Future of the American NATO Commitment ......... 109 Dr...avenues of approach to the ques- tion. Dr. George H. Quester approached NATO’s future from the peespective of American political philosophy. Dr. Robert L...offices whose assign- ment would be to conduct long-range planning on a continuing basis. 85 The Atlantic Alliance: Looking Ahead Dr. Robert L. Pfaltzgraff

Development of a Robust Static Punch Experiment for Screening Unprocessed Ultra-High Molecular Weight Polyethylene (UHMWPE) Unidirectional Cross-Ply Material

DTIC Science & Technology

2014-09-01

Cross-Ply Material by David Gray, Robert Kaste , and Paul Moy ARL-TR-7090 September 2014...Screening Unprocessed Ultra-High Molecular Weight Polyethylene (UHMWPE) Unidirectional Cross-Ply Material David Gray, Robert Kaste , and Paul...ELEMENT NUMBER 6. AUTHOR(S) David Gray, Robert Kaste , and Paul Moy 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7

Civil-Military Relations: From Vietnam to Operation Iraqi Freedom

DTIC Science & Technology

2009-05-01

Robert F. Baumann, Ph.D. Graduate Degree Programs ii Abstract CIVIL-MILITARY RELATIONS: FROM VIETNAM TO OPERATION IRAQI FREEDOM by MAJOR Brandon...Oxford: Oxford University Press, 2007), 285-324. 43 Ibid. 44 Robert M. Gates, 2008 National Defense Strategy (Washington D.C.: Department Of Defense...Dereliction of Duty: Lyndon Johnson, Robert McNamara, the Joint Chiefs of Staff, and the Lies That Led to Vietnam (New York: HarperCollins, 1997), 13. 60

Organizational Culture Challenges to Interagency and Intelligence Community Communication and Interaction

DTIC Science & Technology

2006-05-31

York: McGraw-Hill, 2003), p 121. 103 Gortner, Mahler, and Nicholson, p 74. 104 Robert B. Denhardt, Theories of Public Organization. (Belmont, CA...Uninformed: Government Secrecy in the 1980’s. New York: Pilgrim Press, 1984. Denhardt, Robert B. Theories of Public Organization. Belmont, CA: Brooks/Cole...Fixing Intelligence: For a More Secure America. New Haven, CT: Yale University Press, 2003. Odom, William E. and Robert Dujarric. America’s Inadvertent

Improvements to the Understanding of the Fire Performance of Wood over the Past 30 Years-A Tribute to Robert Hawthorne White

Treesearch

Samuel L. Zelinka; Mark A. Dietenberger; Laura E. Hasburgh; Keith J. Bourne; Charles Boardman

2015-01-01

Dr. Robert Hawthorne White had a 31 year career researching the fire performance of wood and wood composites at the USDA Forest Products Laboratory. Over his career, Dr. White made substantial contributions to codes, standards, and regulations pertaining to the design of wood structures. This review article summarizes Robert’s major accomplishments as a tribute to his...

In re Marriage of Moschetta.

PubMed

1994-06-10

Cynthia Moschetta petitioned to obtain separation from her husband, Robert Moschetta, and to establish her maternity as to Marissa Moschetta, who was conceived pursuant to a traditional surrogacy contract. Elvira Jordan, the surrogate mother, sought to join the dissolution action, and Robert Moschetta requested judgment of dissolution. The Orange County Superior Court awarded joint legal and physical custody to Elvira Jordan and Robert Moschetta. Robert Moschetta appealed, challenging the determination that Jordan is the legal mother of Marissa and contending that Cynthia Moschetta is the legal mother of the child by virtue of the Uniform Parentage Act. The appellate court affirmed Jordan's parental rights, reversed the awarding of joint physical custody, remanded the latter question for reevaluation, and called for legislative guidance on the problems arising from surrogacy arrangements.

John Bowlby and ethology: an annotated interview with Robert Hinde.

PubMed

Bowlby, John

2007-12-01

From the 1950s, John Bowlby, one of the founders of attachment theory, was in personal and scientific contact with leading European scientists in the field of ethology (e.g., Niko Tinbergen, Konrad Lorenz, and especially Robert Hinde). In constructing his new theory on the nature of the bond between children and their caregivers, Bowlby profited highly from their new approach to (animal) behavior. Hinde and Tinbergen in their turn were influenced and inspired by Bowlby's new thinking. On the basis of extensive interviews with bowlby's colleague and lifelong friend Robert Hinde and on the basis of archival materials, both the relationship between John Bowlby and Robert Hinde and the cross-fertilization of ethology and attachment theory are described.

A Legion Apart

DTIC Science & Technology

2012-03-16

NUMBER Colonel Robert Mundell Department of Command, Leadership, & Management 9. SPONSORING...Colonel Robert Mundell Project Adviser This SRP is submitted in partial fulfillment of the requirements of the Master of

Reliability and Maintainability Analysis: A Conceptual Design Model

DTIC Science & Technology

1972-03-01

Elements For a System I. Research ane Development A. Preliminary design and engineering B. Fabrication of test equipment C. Test operations D...reliability racquiro:wents, little, if any, modu larzation and auto- matic test features would be incorporated in the subsystem design, limited reliability...niaintaina~ility testing and monitoring would be conducted turing dev!qopmcnt, and little Quality Control effort, in the rell ability/’uaintainalility

Measuring Meaningful Outcomes in Consequential Contexts: Searching for a Happy Medium in Educational Technology Research (Phase II)

ERIC Educational Resources Information Center

Ross, Steven M.; Morrison, Jennifer R.

2014-01-01

In a paper published 25 years ago, Ross and Morrison ("Educ Technol Res Dev" 37(1):19-33, 1989) called for a "happy medium" in educational technology research, to be achieved by balancing high rigor of studies (internal validity) with relevance to real-world applications (external validity). In this paper, we argue that,…

Advancing Research on Comparative and International Education in Asia: Contribution of the "Asia Pacific Education Review"

ERIC Educational Resources Information Center

Gok, Enes; Weidman, John C.

2015-01-01

This article explored the contribution of Asia Pacific Education Review (APER) to expanding the scope of research on comparative and international education in Asia. We developed a rubric based on extensive studies (Rust et al. in "Comp Educ Rev," 43(1):86-109, 1999; Foster et al. in "Int J Educ Dev" 32:711-732, 2012) of…

Reliability of the ADI-R for the Single Case-Part II: Clinical versus Statistical Significance

ERIC Educational Resources Information Center

Cicchetti, Domenic V.; Lord, Catherine; Koenig, Kathy; Klin, Ami; Volkmar, Fred R.

2014-01-01

In an earlier investigation, the authors assessed the reliability of the ADI-R when multiple clinicians evaluated a single case, here a female 3 year old toddler suspected of having an autism spectrum disorder (Cicchetti et al. in "J Autism Dev Disord" 38:764-770, 2008). Applying the clinical criteria of Cicchetti and Sparrow ("Am J…

Brief Report: Predicting Inner Speech Use amongst Children with Autism Spectrum Disorder (ASD)--The Roles of Verbal Ability and Cognitive Profile

ERIC Educational Resources Information Center

Williams, David M.; Jarrold, Christopher

2010-01-01

Studies of inner speech use in ASD have produced conflicting results. Lidstone et al., J "Autism Dev Disord" (2009) hypothesised that Cognitive Profile (i.e., "discrepancy" between non-verbal and verbal abilities) is a predictor of inner speech use amongst children with ASD. They suggested other, contradictory results might be explained in terms…

Brief Report: Self-Based and Mechanical-Based Future Thinking in Children with Autism Spectrum Disorder

ERIC Educational Resources Information Center

Marini, A.; Ferretti, F.; Chiera, A.; Magni, R.; Adornetti, I.; Nicchiarelli, S.; Vicari, S.; Valeri, G.

2016-01-01

This brief report is a partial replication of the study by Jackson and Atance ("J Dev Disabil" 14:40-45, 2008) assessing nonverbal Self-based and Mechanical-based future thinking (FT) in children with Autism Spectrum Disorder (ASD). In a first step, these tasks were administered to 30 children with ASD. The two Self-based tasks were then…

Brief Report: Repetitive Behaviors in Young Children with Autism Spectrum Disorder and Developmentally Similar Peers--A Follow Up to Watt et al. (2008)

ERIC Educational Resources Information Center

Barber, Angela B.; Wetherby, Amy M.; Chambers, Nola W.

2012-01-01

The present study extended the findings of Watt et al. (J Autism Dev Disord 38:1518-1533, 2008) by investigating repetitive and stereotyped behaviors (RSB) demonstrated by children (n = 50) and typical development (TD; n = 50) matched on developmental age, gender, and parents' education level. RSB were coded from videotaped Communication and…

The Autism Diagnostic Observation Schedule, Module 4: Application of the Revised Algorithms in an Independent, Well-Defined, Dutch Sample (N = 93)

ERIC Educational Resources Information Center

de Bildt, Annelies; Sytema, Sjoerd; Meffert, Harma; Bastiaansen, Jojanneke A. C. J.

2016-01-01

This study examined the discriminative ability of the revised Autism Diagnostic Observation Schedule module 4 algorithm (Hus and Lord in "J Autism Dev Disord" 44(8):1996-2012, 2014) in 93 Dutch males with Autism Spectrum Disorder (ASD), schizophrenia, psychopathy or controls. Discriminative ability of the revised algorithm ASD cut-off…

DDG 1000 Zumwalt Class Destroyer (DDG 1000)

DTIC Science & Technology

2013-12-01

Missile Defense Radar is the most cost-effective solution to fleet air and missile defense requirements. The Secretary of the Navy notified Congress...not reach an affordable solution and deliveries of these components for DDG 1002 were becoming time-critical. The Navy concurrently pursued a steel...DD(X) Construction (Shared) (Sunk) 2464 DD(X) Sys Design, Dev & Integration (Shared) (Sunk) 2465 DC Survivability (Shared) (Sunk) 2466 MFR

Development of High Level Electrical Stress Failure Threshold and Prediction Model for Small Scale Junction Integrated Circuits

DTIC Science & Technology

1978-09-01

AWACS EMP Guidelines presents two different models to predict the damage pcwer of the dev-ce and the circuit damage EMP voltage ( VEMP ). Neither of...calculated as K P~ I V BD 6. The damage EMP voltage ( VEMP ) is calculated KZ EMP +IZ =D +BD VBD1F 7. The damage EMP voltage is calculated for collector

78 FR 32214 - Land Acquisitions: Appeals of Land Acquisition Decisions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-29

...; 134D0102DR-DS5A300000-DR.5A311.IA000113; Docket ID: BIA-2013-0005] RIN 1076-AF15 Land Acquisitions: Appeals... trust under this part, including broadening notice of any right to file an administrative appeal. DATES... the United States acquired title. See, e.g., Neighbors for Rational Dev., Inc. v. Norton, 379 F.3d 956...

The Effectiveness of Cognitive Exposure & Skills Group Manualized Treatments in OIF/OEF Female Veterans

DTIC Science & Technology

2011-04-01

2004). PTSD and somatization in women treated at a VA primary care clinic. Psychosomatics, 45, 291-296. Foa, E. B., Dancu, C. V., Hembree, E...were clinically significant elevations (> 70) on the Demoralization, Somatic Complaints, Low Positive Emotion of the Restructured Clinical scales and... Hypochondriasis , Psych Dev = Psychopathic Deviate, Masc-Fem = Masculinity- Femininity, Psychasth = Psychasthenia, Schizoph = Schizophrenia; Soc Introv

Student-Content Interactions in Online Courses: The Role of Question Prompts in Facilitating Higher-Level Engagement with Course Content

ERIC Educational Resources Information Center

Ertmer, Peggy A.; Sadaf, Ayesha; Ertmer, David J.

2011-01-01

This study examined the relationships among question types and levels and students' subsequent responses/interactions in online discussion forums. Question prompts were classified both by type, as outlined by Andrews ("POD Q J Prof Organ Dev Net Higher Education" 2(34):129-163, 1980), and by levels of critical thinking, as outlined by Bloom…

Behavioral Development and Sociodemographics of Infants and Young Children at Higher and Lower Risk for Autism Spectrum Disorders

ERIC Educational Resources Information Center

Feldman, Maurice A.; Hendry, Amanda M.; Ward, Rebecca A.; Hudson, Melissa; Liu, Xudong

2015-01-01

Identification of early signs of Autism Spectrum Disorder (ASD) could lead to earlier diagnosis and intervention. This cross-sectional study used the Parent Observation of Early Markers Scale (POEMS, Feldman et al. in "J Autism Dev Disord" 42:13-12, 2012) to identify early signs of ASD in 69 ASD high-risk (older sibling diagnosed with…

Hydrocarbon Fuel Thermal Performance Modeling based on Systematic Measurement and Comprehensive Chromatographic Analysis

DTIC Science & Technology

2016-07-27

is a common requirement for aircraft, rockets , and hypersonic vehicles. The Aerospace Fuels Quality Test and Model Development (AFQTMoDev) project...was initiated to mature fuel quality assurance practices for rocket grade kerosene, thereby ensuring operational readiness of conventional and...and reliability, is a common requirement for aircraft, rockets , and hypersonic vehicles. The Aerospace Fuels Quality Test and Model Development

Mucin (MUC1) Expression and Function in Prostate Cancer Cells

DTIC Science & Technology

2001-09-01

Interactions at the Cell Surface of Mouse Uterine Epithelial Cells and Periimplantation -Stage Embryos. Trophoblast Res., 4:211-241, 1990. 37. Dutt...and Julian, J. Heparan Sulfate Proteoglycan Expression by Periimplantation Stage Embryos. Dev. Biol. 155:97-106,1993. 56. Rohde, L.H., and Carson...Modulators of Embryo-Uterine Epithelial Cell Attachment. In: S.K. Dey (ed.), Molecular and Cellular Aspects of Periimplantation Processes, Springer

eddy4R 0.2.0: a DevOps model for community-extensible processing and analysis of eddy-covariance data based on R, Git, Docker, and HDF5

NASA Astrophysics Data System (ADS)

Metzger, Stefan; Durden, David; Sturtevant, Cove; Luo, Hongyan; Pingintha-Durden, Natchaya; Sachs, Torsten; Serafimovich, Andrei; Hartmann, Jörg; Li, Jiahong; Xu, Ke; Desai, Ankur R.

2017-08-01

Large differences in instrumentation, site setup, data format, and operating system stymie the adoption of a universal computational environment for processing and analyzing eddy-covariance (EC) data. This results in limited software applicability and extensibility in addition to often substantial inconsistencies in flux estimates. Addressing these concerns, this paper presents the systematic development of portable, reproducible, and extensible EC software achieved by adopting a development and systems operation (DevOps) approach. This software development model is used for the creation of the eddy4R family of EC code packages in the open-source R language for statistical computing. These packages are community developed, iterated via the Git distributed version control system, and wrapped into a portable and reproducible Docker filesystem that is independent of the underlying host operating system. The HDF5 hierarchical data format then provides a streamlined mechanism for highly compressed and fully self-documented data ingest and output. The usefulness of the DevOps approach was evaluated for three test applications. First, the resultant EC processing software was used to analyze standard flux tower data from the first EC instruments installed at a National Ecological Observatory (NEON) field site. Second, through an aircraft test application, we demonstrate the modular extensibility of eddy4R to analyze EC data from other platforms. Third, an intercomparison with commercial-grade software showed excellent agreement (R2 = 1.0 for CO2 flux). In conjunction with this study, a Docker image containing the first two eddy4R packages and an executable example workflow, as well as first NEON EC data products are released publicly. We conclude by describing the work remaining to arrive at the automated generation of science-grade EC fluxes and benefits to the science community at large. This software development model is applicable beyond EC and more generally builds the capacity to deploy complex algorithms developed by scientists in an efficient and scalable manner. In addition, modularity permits meeting project milestones while retaining extensibility with time.

Robert Tirawat | NREL

Science.gov Websites

-performance, high-reliability systems that use concentrated sunlight to generate power. Recently, Robert has been involved developing a high-efficiency solar selective absorber and anti-corrosion coatings

Numerical Methods in Atmospheric and Oceanic Modelling: The Andre J. Robert Memorial Volume

NASA Astrophysics Data System (ADS)

Rosmond, Tom

Most people, even including some in the scientific community, do not realize how much the weather forecasts they use to guide the activities of their daily lives depend on very complex mathematics and numerical methods that are the basis of modern numerical weather prediction (NWP). André Robert (1929-1993), to whom Numerical Methods in Atmospheric and Oceanic Modelling is dedicated, had a career that contributed greatly to the growth of NWP and the role that the atmospheric computer models of NWP play in our society. There are probably no NWP models running anywhere in the world today that do not use numerical methods introduced by Robert, and those of us who work with and use these models everyday are indebted to him.The first two chapters of the volume are chronicles of Robert's life and career. The first is a 1987 interview by Harold Ritchie, one of Robert's many proteges and colleagues at the Canadian Atmospheric Environment Service. The interview traces Robert's life from his birth in New York to French Canadian parents, to his emigration to Quebec at an early age, his education and early employment, and his rise in stature as one of the preeminent research meteorologists of our time. An amusing anecdote he relates is his impression of weather forecasts while he was considering his first job as a meteorologist in the early 1950s. A newspaper of the time placed the weather forecast and daily horoscope side by side, and Robert regarded each to have a similar scientific basis. Thankfully he soon realized there was a difference between the two, and his subsequent career certainly confirmed the distinction.

The Vietnam Cauldron: Defense Intelligence in the War for Southeast Asia

DTIC Science & Technology

2012-01-01

For the Patriots. Major Robert P. Perry, USA Celeste M. Brown Vivienne A. Clark Dorothy M. Curtiss Joan K. Pray Doris J. Watkins Colonel Charles R. Ray...USA Chief Warrant Officer Robert W. Prescott, USA Chief Warrant Officer Kenneth D. Welch, USA Petty Officer First Class Michael R. Wagner, USN...Marshall Karl W. Teepe Patricia E. Mickley Robert J. Hymel Rosa M. Chapa Sandra N. Foster Charles E. Sabin i Defense Intelligence Historical Perspectives

China: Suspected Acquisition of U.S. Nuclear Weapon Secrets

DTIC Science & Technology

2006-02-01

Benjamin Kang, “China Nuclear Halt May Stem From Deal,” Reuters, July 30, 1996; Robert Karniol, “Nuclear Blast Heralds A Chinese Moratorium,” Jane’s Defense...Leak,” New York Times, April 8, 1999. 12 FBI, “Statement by FBI Director Robert S. Mueller,” April 9, 2003; Katrina Leung Affidavit; James J. Smith...the appropriate congressional committees and the White House on April 21, 1999. Robert Walpole, the National Intelligence Officer for Strategic and

Reducing Long-Term Costs While Preserving a Robust Strategic Airlift Fleet: Options for the Current Fleet and Next-Generation Aircraft

DTIC Science & Technology

2013-01-01

Ghashghai, Jeff Hagen, Thomas Hamilton, Gregory G. Hildebrandt , Yool Kim, Robert S. Leonard, Rosalind Lewis, Elvira N. Loredo, Daniel M. Norton, David T...Joan Cornuet, Mel Eisman, Chris Fitzmartin, Jean R. Gebman, Elham Ghashghai, Jeff Hagen, Thomas Hamilton, Gregory G. Hildebrandt , Yool Kim, Robert...Hagen, Thomas Hamilton, Gregory G. Hildebrandt , Yool Kim, Robert S. Leonard, Rosa- lind Lewis, Elvira N. Loredo, Daniel M. Norton, David T. Orletsky

Building Maintenance and Repair Data for Life-Cycle Cost Analyses: Electrical Systems.

DTIC Science & Technology

1991-05-01

Repair Data for Life-Cycle Cost Analyses: Electrical Systems by Edgar S. Neely Robert D. Neathammer James R. Stirn Robert P. Winkler This research...systems have been developed to assist planners in preparing DD Form 1391 documentation, designers in life-cycle cost component selection, and maintainers...Maintenance and Repair Data for Life-Cycle Cost Analyses: RDTE dated 1980 Electrical Systems REIMB 1984 - 1989 6. AUTH4OR(S) Edgar S. Neely, Robert D

Getting America Ready for Japanese Science and Technology Held at Washington, DC on 7-8 February 1985.

DTIC Science & Technology

1985-05-15

TRANSLATION: A LONG-TERM SOLUTION MACHINE TRANSLATIONS: DEVELOPMENTS AND PROSPECTS 96 Robert A. Russell, Assistant Professor, Department of Asian and...chairman of the board of WCC, Chicago. He is a member of the Japanese National Automatic Translation Telephone Development Committee. 1 ROBERT A. RUSSELL...redussol- Westerism through indexing enineiring student to trai- speaking M Ono"e langisage. 067 pubfiahang-some in services. said Robert W. Gib- law

Structural Optimization of a Distributed Actuation System in a Flexible In-Plane Morphing Wing

DTIC Science & Technology

2007-06-01

Captain, USAF Approved: /signed/ 11 Jun 2007 Dr. Robert Canfield (Chairman) date /signed/ 11 Jun 2007 Dr. Brian Sanders (Member) date /signed/ 11 Jun...can be seen here at the Camp Roberts Flight Test Range [11]. separation, which ultimately increased the overall lift. During wind tunnel tests, the...Matlabr . The outermost loop was written by Mark Spillman and Dr. Robert Canfield and was based on Schittkowski’s Sequential Quadratic Programming (SQP

The Federal Role in Funding State and Local Infrastructure: Two Reports on Public Works Financing

DTIC Science & Technology

1993-08-01

comments are welcome on any of these reports. For further information on the Federal Infrastructure Strategy Program, please contact Robert A. Pietrowsky ...Eugene Z. Stakhiv, Chief, Policy and Special Studies Division; and the FIS Study Team which includes Mr. Robert A. Pietrowsky , Program Manager, Mr...and visiting fellow of the Navigation Division of IWR, and Mr. Robert Pietrowsky for their helpful comments on the introduction. Mention must also be

Associate Administrator, Robert Lightfoot address the Marshall Association.

NASA Image and Video Library

2015-07-28

NASA ASSOCIATE ADMINISTRATOR ROBERT LIGHTFOOT SHARED HIS PERSONAL REFLECTIONS ON LEADERSHIP WITH MARSHALL ASSOCIATION MEMBERS AND GUESTS DURING A LUNCHEON JULY 28 AT NASA’S MARSHALL SPACE FLIGHT CENTER.

Development of a Free-Electron Laser Center and Research in Medicine, Biology and Materials Science,

DTIC Science & Technology

1992-05-14

Elastin Production in Tissue Culture", Debra A.Gonzalez MD, David L. Zealear, PhD., J.M. Davidson, PhD., Robert H. Ossoff, MD, DMD , August 1990...Otolaryngoloty-Head and Neck Surgery. K. "CO2 Laser Micromanipulator Parallax Error Resolved, Jay Werkhaven,MD, Jerri Tribble, and Robert H. Ossoff, MD, DMD ...of the Upper Aerodigestive Tract, Robert H. Ossoff, MD, DMD , Al Aly, MD, Nick Houchin, AAS, and Debra Gonzalez, MD, Vanderbilt University, Nashville

America’s last battles: Organizing brigades to win the peace lessons from East Timor, Afghanistan, and Iraq

DTIC Science & Technology

2004-06-17

Graduate Degree Programs Robert F. Baumann, Ph.D. The opinions and conclusions expressed herein are those of the student author and do not...primary research method this study will follow is the case study method as outlined in Robert K. Yin’s, Case Study Research: Design and Methods. By using...The method is also policy relevant as it generates lessons relevant to different situations. In Robert K. Yin’s words, “An important step . . . is the

Robert Halliday Gunning and the Victoria Jubilee prizes.

PubMed

Baillie, T W

2003-05-01

More than a century after the death of Robert Halliday Gunning, a large number of lectureships and prizes bearing his name continue to be awarded by scientific bodies and learned institutions in Scotland. Most of these awards were endowed in HM Queen Victoria s Jubilee year (1887-88) and bear the additional qualification 'Victoria Jubilee'. An account of the life of Robert Gunning and his various endowments is complemented by an analysis of the factors which determined the nature of his benefactions.

Environmental Analysis of Lake Pontchartrain, Louisiana, Its Surrounding Wetlands, and Selected Land Uses. Volume 1.

DTIC Science & Technology

1980-02-01

M. Darnell,* Richard W. Heard,* Robert C. Cashner,* and Olivia House* e Graduate Modeling Robert E. Hinchee and Linda A. Deegan Students Grassbeds...James H. Stone, B. T. Gael, Linda A. Deegan , Robert E. Hinchee, John W. Day, Jr., Leonard M. Bahr, Jr., and R. E. Turner R. C. Cashner is affiliated with...Sciences Linda A. Deegan , Graduate Assistant David D. Dow, Research Associate III Nancy A. Drummond, Graduate Assistant Marion Fannaly, Research Associate

Two autographs: Cecile Dewitt and Robert Hawking (for Steven Hawking)

NASA Astrophysics Data System (ADS)

Gaina, Alex

2007-12-01

Two autographs given to author by professor Cecile Dewitt and Robert Hawking (the son of Steven Hawking for his father) in 1987 during the Quantum Gravity Seminar in Moscow are presented. The first was given during a visit to Physical Institute of the Academy of sciences of the USSR, where a seminar held in the Theoretical department. the second was given during a lunch with Steven Hawking, Andrei Linde and Robert Hawking at the 2-nd floor of the Conference floor.

Group for High Resolution Sea Surface Temperature (GHRSST) Analysis Fields Inter-Comparisons. Part 1: A GHRSST Multi-Product Ensemble (GMPE)

DTIC Science & Technology

2012-05-02

Le Borgne, P., Poulter, D., Vazquez-Cuervo, J., Armstrong, E., Beggs, H., Llewellyn - Jones , D., Minnett, P., Merchant, C., Evans, R., 2009. The GODAE...Donlon i, Chelle Gentemann j, Robert Grumbine k, Shiro Ishizaki l, Eileen Maturi b, Richard W. Reynoldsm, Jonah Roberts- Jones a a Met Office, Exeter...high-resolution sea surface temperature pilot project. Oceanography 22, 34–45. Donlon, C.J., Martin, M., Stark, J.D., Roberts- Jones , J., Fiedler, E

Investigation of the Numerical Methods of Finite Differences and Weighted Residuals for Solution of the Heat Equation.

DTIC Science & Technology

1982-03-01

OF FINITE DIFFERENCES AND WEIGHTED RESIDUALS FOR SOLUTION OF THE HEAT EQUATION a THESIS J’. AFIT/GNE/PH/81-7 *-.1 Robert Naegeli .. ....... J --aC t...Institute of Technology Air University in Partial Fulfillment of the a Requirements for the Degree of Master of Science by Robert E. Naegeli , M.S. Capt USAF...a time which proved to be one of great personal adjustment and turmoil. Robert E. Naegeli ii Contents Page Preface

Competent, Confident and Agile? A Study of the U.S. Army Leadership Requirements Model and its Application for U.S. Army Company Commanders

DTIC Science & Technology

2011-06-10

Thesis Committee Chair John M. Persyn, Ph.D. , Member LTC Eric K. Dunahee, M.S. , Member Robert D. Bloomquist, M.A...Accepted this 10th day of June 2011 by: , Director, Graduate Degree Programs Robert F. Baumann, Ph.D. The opinions and conclusions expressed...have been possible without the support of my committee, Dr. John M. Persyn, LTC Eric K. Dunahee and Mr. Robert D. Bloomquist. Thank you for your

7. Historic American Buildings Survey, Robert E. Cooper, Photographer January, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Historic American Buildings Survey, Robert E. Cooper, Photographer January, 1961 DEMOLITION, SHOWING STRUCTURAL ELEMENTS. - American Life Insurance Company Building, 330-336 Walnut Street, Philadelphia, Philadelphia County, PA

Official portrait of astronaut Robert C. Springer

NASA Technical Reports Server (NTRS)

1988-01-01

Official portrait of astronaut Robert C. Springer, United Stated Marine Corps (USMC) Colonel, member of Astronaut Class 9 (1980), and mission specialist. Springer wears launch and entry suit (LES) while holding helmet.

Association of American Indian Physicians

MedlinePlus

... Scholars Program This program of the Robert Wood Johnson Foundation is a leadership development opportunity for practitioners ... for Clinical Scholars program supported by Robert Wood Johnson Foundation will open in January 2018. https://t. ...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dighe, Kalpak Arvind

Several 40+ hour data records obtained in Oct 2010 from the Los Alamos Portable Pulser Facility (LAPP) Operational clocks show variations of {approx} 27 nsec. Several 16+ hour data records obtained in Aug 2010 from non-operational clocks like those used operationally from 2005 to the present show variations of {approx} 35 nsec. SLRE variability is xxx +/- yyy sec (std dev). SLRE occasionally show unusual events such as those discussed by Pongratz. We will continue to study and monitor.

78 FR 77144 - Announcement of Funding Awards for Fiscal Year 2013 for the Housing Choice Voucher Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-20

..., HOPEWELL, VA 23860. VA: VIRGINIA HSG REDEV AUTH.. 601 SOUTH 0 9,400 BELVIDERE ST, RICHMOND, VA 23220. VT...: HENDERSON HA 111 SOUTH ADAMS 0 17,800 ST, HENDERSON, KY 42420. KY: CYNTHIANA HA 149 FEDERAL ST, 0 4,200... 20895. MI: MICHIGAN STATE HSG DEV PO BOX 30044, 0 84,800 AUTH. LANSING, MI 48909. MN: VIRGINIA HRA PO...

No Evidence against Sketch Reinstatement of Context, Verbal Labels or the Use of Registered Intermediaries for Children with Autism Spectrum Disorder: Response to Henry et al. (2017)

ERIC Educational Resources Information Center

Dando, Coral J.; Ormerod, Thomas C.; Cooper, Penny; Marchant, Ruth; Mattison, Michelle; Milne, Rebecca; Bull, Ray

2018-01-01

Recently, Henry et al. ("J Autism Dev Disord" 8:2348-2362, 2017) found no evidence for the use of Verbal Labels, Sketch Reinstatement of Context and Registered Intermediaries by forensic practitioners when interviewing children with a diagnosis of autism spectrum disorder. We consider their claims, noting the limited ecological validity…

Commentary on "The Evolutionary Origin of Female Orgasm" by M. Pavlicev and G. Wagner, 2016, J. Exp. Zool. (Mol. Dev. Evol.) 326(6):326-337.

PubMed

Komisaruk, Barry R

2016-12-01

Evidence is presented as an alternative to the authors' claims that in the course of evolution, a link between orgasm and ovulation has been lost in women, that evolutionary changes in clitoral anatomy underlie this loss, and that women's orgasm plays no significant role in reproduction. © 2016 Wiley Periodicals, Inc.

Rational Design of Rho Protein Inhibitors

DTIC Science & Technology

2006-09-01

X- ray crystallographic techniques for structure determination. This training regimen has consisted of formal training either individually from...facility (Brenda Temple, Ph.D.), members of the LDDN at Harvard University (Ross Stein, Ph.D. and Li-An Yeh, Ph.D.), the director of the X- ray core...initiation but essential for metastasis. Genes Dev, 2005. Electronic publication ahead of print. 23. Zhang J-H, Chung TDY, and Oldenburg KR. A

A Replication and Extension of the PEERS Intervention: Examining Effects on Social Skills and Social Anxiety in Adolescents with Autism Spectrum Disorders

ERIC Educational Resources Information Center

Schohl, Kirsten A.; Van Hecke, Amy V.; Carson, Audrey Meyer; Dolan, Bridget; Karst, Jeffrey; Stevens, Sheryl

2014-01-01

This study aimed to evaluate the Program for the Education and Enrichment of Relational Skills (PEERS: Laugeson et al. in "J Autism Dev Disord" 39(4):596-606, 2009). PEERS focuses on improving friendship quality and social skills among adolescents with higher-functioning ASD. 58 participants aged 11-16 years-old were randomly assigned to…

Theory and Device Modeling for Nano-Structured Transistor Channels

DTIC Science & Technology

2011-06-01

zinc oxide ( ZnO ) thin film transistors ( TFTs ) that contain nanocrystalline grains on the order of ~20nm. The authors of ref. 1 present results...problem in order to determine the threshold voltage. 15. SUBJECT TERMS nano-structured transistor , mesoscopic, zinc oxide , ZnO , field-effect...and R. Neidhard, “Microwave ZnO Thin - Film Transistors ”, IEEE Electron Dev. Lett. 29, 1024 (2008); doi: 10.1109/LED.2008.2001635.

A Research Program in Computer Technology. 1987 Annual Technical Report

DTIC Science & Technology

1990-07-01

TITLE (Indcle Security Clanificstion) 1987 Annual Technical Report: *A Research Program in Computer Technology (Unclassified) 12. PERSONAL AUTHOR(S) IS...distributed processing, survivable networks 17. NCE: distributed processing, local networks, personal computers, workstation environment 18. SC Dev...are the auw’iors and should not be Interpreted as representIng the official opinion or policy of DARPA, the U.S. Government, or any person or agency

Cyber Fundamental Exercises

DTIC Science & Technology

2013-03-01

the /bin, /sbin, /etc, /var/log, /home, /proc, /root, /dev, /tmp, and /lib directories • Describe the purpose of the /etc/shadow and /etc/ passwd ...UNLIMITED 19 2.6.2 /etc/ passwd and /etc/shadow The /etc/shadow file didn’t exist on early Linux distributions. Originally only root could access the...etc/ passwd file, which stored user names, user configuration information, and passwords. However, when common programs such as ls running under

DEVSML 2.0: The Language and the Stack

DTIC Science & Technology

2012-03-01

problems outside it. For example, HTML for web pages, Verilog and VHDL for hardware description, etc. are DSLs for very specific domains. A DSL can be...Engineering ( MDE ) paradigm where meta-modeling allows such transformations. The metamodeling approach to Model Integrated Computing (MIC) brings...University of Arizona, 2007 [5] Mittal, S, Martin, JLR, Zeigler, BP, "DEVS-Based Web Services for Net-centric T&E", Summer Computer Simulation

Games for Health 2005

DTIC Science & Technology

2005-10-01

to be exposed to in terms of validation and research.� This is important because the game development community is used to only market validation...dev, aggressively pursuing new frontiers.� We are working on ways within our greater project and future events to explain more about game development production...technology providers that permeate the game development space. By bringing over these key leaders we can further grow the overall community of

Open Component Portability Infrastructure (OPENCPI)

DTIC Science & Technology

2009-11-01

Disk Drive 7 1 www.antec.com P182 $120. ATX Mid Tower Computer Case 8 1 www.xilinx.com HW-V5-ML555-G $2200. Xilinx ML555 V5 Dev Kit Notes: Cost...s/ GEORGE RAMSEYER EDWARD J. JONES, Deputy Chief Work Unit Manager Advanced Computing ...uniquely positioned to meet the goals of the Software Systems Stockroom (S3) since in some sense component-based systems are computer -science’s

Executive Handbook for Financial Management.

DTIC Science & Technology

1981-01-01

Review 3-U Section V Fund Control 3-8 Section VI Reimbursement Programs- 3-A Section VII Financing Remote Activities 3-13 Section VIII Monitoring...conduct of the dev- elopment effort. For more on this subject, see chapt er 9. k. Army procurement accounts. The reimbursable (customer) programs for...obligations. When these orders change or get lost, duplicated, or cancelled, they impact on the Army’s reimbursable obligational authority. This reimbursable

Assessment Alternatives for a High Skill MOS

DTIC Science & Technology

1975-12-01

tests. CR measurement advocates frequently claim that variance dependent statistics are inapplicable In CR test- ing because CR test scores have...rather than statistically . The Spearman- Brown reliability coefficient was .70. 17 In 1964, Shriver, Fink and Trexler (76) modified the M-33...ATTN: ATSW-SE-L 1 USA Cmd ft General Stf C- IVge . Ft Leavenworth, ATTN: Ed Advisor 1 USA Combined Arms Cmbt Dev Act, Ft Leavenworth, ATTN: DepCdr

The Role of a Novel Myosin Isoform in Prostate Cancer Metastasis

DTIC Science & Technology

2013-10-01

of unconventional myosin function and targeting, Annu. Rev. Cell Dev. Biol. 27 (2011) 133–155. [42] W. Kliche, S. Fujita- Becker , M. Kollmar, D.J...tissue-specific diseases (laminopathies), including Emery–Dreifuss muscular dystrophy , Dunnigan-type familial partial lipodystrophy (FPLD), and...structure of the C-terminal domain of lamin A/C, mutated in muscular dystrophies , cardiomyopathy, and partial lipodystrophy. Structure 10, 811–823

The End of the Reading Age: Grade and Age Effects in Early Schooling

ERIC Educational Resources Information Center

Alexander, James R.M.; Martin, Frances

2004-01-01

During the school years, psychological test norms may be indexed by age or by grade. A number of studies have shown that using age-based norms appears to produce biases associated with grade assignment. Cahan and Cohen [Child Dev. 60 (1989) 1239-1249] showed that the effect of one grade was over twice the effect of 1 year of age for most verbal…

Brief Report: Preliminary Evaluation of the Theory of Mind Inventory and Its Relationship to Measures of Social Skills

ERIC Educational Resources Information Center

Lerner, Matthew D.; Hutchins, Tiffany L.; Prelock, Patricia A.

2011-01-01

This study presents updated information on a parent-report measure of Theory of Mind (ToM), formerly called the Perception of Children's Theory of Mind Measure (Hutchins et al., "J Autism Dev Disord" 38:143-155, 2008), renamed the Theory of Mind Inventory (ToMI), for use with parents of children with autism spectrum disorder (ASD). This study…

Comparative study of diagnostic accuracy of established PCR assays and in-house developed sdaA PCR method for detection of Mycobacterium tuberculosis in symptomatic patients with pulmonary tuberculosis.

PubMed

Nimesh, Manoj; Joon, Deepali; Pathak, Anil Kumar; Saluja, Daman

2013-11-01

Indian contribution to global burden of tuberculosis is about 26%. In the present study we have developed an in-house PCR assay using primers for sdaA gene of Mycobacterium tuberculosis and evaluated against already established primers devR, IS6110, MPB64, rpoB primers for diagnosis of pulmonary tuberculosis. Using universal sample preparation (USP) method, DNA was extracted from sputum specimens of 412 symptomatic patients from Delhi, India. The DNA so extracted was used as template for PCR amplification using primers targeting sdaA, devR, IS6110, MPB64 and rpoB genes. Out of 412, 149 specimens were considered positive based on composite reference standard (CRS) criteria. The in-house designed sdaA PCR showed high specificity (96.5%), the high positive likelihood ratio (28), the high sensitivity (95.9%), and the very low negative likelihood ratio (0.04) in comparison to CRS. Based on our results, the sdaA PCR assay can be considered as one of the most reliable diagnostic tests in comparison to other PCR based detection methods. Copyright © 2013 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

Development of battery management system for nickel-metal hydride batteries in electric vehicle applications

NASA Astrophysics Data System (ADS)

Jung, Do Yang; Lee, Baek Haeng; Kim, Sun Wook

Electric vehicle (EV) performance is very dependent on traction batteries. For developing electric vehicles with high performance and good reliability, the traction batteries have to be managed to obtain maximum performance under various operating conditions. Enhancement of battery performance can be accomplished by implementing a battery management system (BMS) that plays an important role in optimizing the control mechanism of charge and discharge of the batteries as well as monitoring the battery status. In this study, a BMS has been developed for maximizing the use of Ni-MH batteries in electric vehicles. This system performs several tasks: the control of charging and discharging, overcharge and over-discharge protection, the calculation and display of state-of-charge (SOC), safety, and thermal management. The BMS is installed in and tested in a DEV5-5 electric vehicle developed by Daewoo Motor Co. and the Institute for Advanced Engineering in Korea. Eighteen modules of a Panasonic nickel-metal hydride (Ni-MH) battery, 12 V, 95 A h, are used in the DEV5-5. High accuracy within a range of 3% and good reliability are obtained. The BMS can also improve the performance and cycle-life of the Ni-MH battery peak, as well as the reliability and the safety of the electric vehicles.

Astronaut Robert L. Crippen prepares for underwater training session

NASA Technical Reports Server (NTRS)

1983-01-01

Astronaut Robert L. Crippen, STS-7 crew commander, adjusts his extravehicular mobility unit's (EMU) gloves prior to donning his helmet for a training session in the weightless environment test facility (WETF).

78 FR 11090 - Flightcrew Member Duty and Rest Requirements; Technical Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-15

... this action, contact Dale E. Roberts, AFS-200, Flight Standards Service, Air Transportation Division...- 5749; email dale[email protected] . For legal questions concerning this action, contact Robert Frenzel...

6. Historic American Buildings Survey Robert W. Kerrigan, Photographer August ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Historic American Buildings Survey Robert W. Kerrigan, Photographer August 24, 1936 INTERIOR DETAIL WEST WALL OF SOCIAL HALL - Trocadero Inn, Sigmund Stern Grove, San Francisco, San Francisco County, CA

6. Watchman Robert 'Jerry' Jones at Camp Dyer. Photographer James ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Watchman Robert 'Jerry' Jones at Camp Dyer. Photographer James Dix Schuyler, 1903. Source: Schuyler report. - Waddell Dam, On Agua Fria River, 35 miles northwest of Phoenix, Phoenix, Maricopa County, AZ

Observation of Two-Dimensional Localized Jones-Roberts Solitons in Bose-Einstein Condensates

NASA Astrophysics Data System (ADS)

Meyer, Nadine; Proud, Harry; Perea-Ortiz, Marisa; O'Neale, Charlotte; Baumert, Mathis; Holynski, Michael; Kronjäger, Jochen; Barontini, Giovanni; Bongs, Kai

2017-10-01

Jones-Roberts solitons are the only known class of stable dark solitonic solutions of the nonlinear Schrödinger equation in two and three dimensions. They feature a distinctive elongated elliptical shape that allows them to travel without change of form. By imprinting a triangular phase pattern, we experimentally generate two-dimensional Jones-Roberts solitons in a three-dimensional atomic Bose-Einstein condensate. We monitor their dynamics, observing that this kind of soliton is indeed not affected by dynamic (snaking) or thermodynamic instabilities, that instead make other classes of dark solitons unstable in dimensions higher than one. Our results confirm the prediction that Jones-Roberts solitons are stable solutions of the nonlinear Schrödinger equation and promote them for applications beyond matter wave physics, like energy and information transport in noisy and inhomogeneous environments.

Cognitive remediation therapy and cognitive behavioral therapy with an older adult with anorexia nervosa: A brief case report.

PubMed

Darcy, Alison M; Fitzpatrick, Kara K; Lock, James

2016-06-01

Cognitive remediation therapy represents a new approach to the treatment of anorexia nervosa (AN) emerging from research, suggesting that adults with chronic AN have specific neurocognitive inefficiencies. Specifically, adults with AN demonstrate an overly detailed cognitive processing bias (Roberts, Tchanturia, & Treasure, 2013) and difficulties shifting set quickly and efficiently (Roberts, Tchanturia, Stahl, Southgate, & Treasure, 2007). These characteristics manifest as rigid, rule-bound, and detail-focused cognitions, beliefs, and behaviors. Versions of these problems appear to persist after weight restoration (Tchanturia et al., 2004) and are observable in patient's healthy sisters (Roberts et al., 2013). Thus, central coherence difficulties and set-shifting problems have been proposed as endophenotypes and maintaining factors of AN (Roberts et al., 2013). (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Integration of new geologic mapping and satellite-derived quartz mapping yields insights into the structure of the Roberts Mountains allochthon applicable to assessments for concealed Carlin-type gold deposits

USGS Publications Warehouse

Holm-Denoma, Christopher S.; Hofstra, Albert H.; Rockwell, Barnaby W.; Noble, Paula J.

2012-01-01

Geologic mapping and remote sensing across north-central Nevada enable recognition of a thick sheet of Middle and Upper Ordovician Valmy Formation quartzite that structurally overlies folded and faulted Ordovician through Devonian stratigraphic units of the Roberts Mountains allochthon. In the northern Independence Mountains and nearby Double Mountain area, the Valmy Formation is in fault contact with Ordovician through Silurian, predominantly clastic, sedimentary rocks of the Roberts Mountains allochthon that were deformed prior to, or during, emplacement of the Valmy thrust sheet. Similar structural relations are recognized discontinuously for 200 kilometers along the strike of the Roberts Mountains allochthon in mapping guided by regional remote-sensing-based (ASTER) quartz maps. Overall thicknesses of deformed Roberts Mountains allochthon units between the base of the Valmy and the top of underlying carbonate rocks that host large Carlin-type gold deposits varies on the order of hundreds of meters but is not known to exceed 700 meters. The base of the Valmy thrust sheet is a complimentary datum in natural resource exploration and mineral resource assessment for concealed Carlin-type gold deposits.

San Joaquin kit fox Vulpes macrotis mutica program, Camp Roberts, California

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Camp Roberts is a California Army National Guard Training Site located in central California. The San Joaquin kit fox, an endangered subspecies of kit fox, has been known to occur at Camp Roberts since 1960. The population of foxes began to increase in the early 1970's when use of rodenticides decreased. In 1987 the California Army National Guard contracted EG G Energy Measurements to conduct a 3-year study to assess the effects of Camp Roberts activities on the kit fox population. The major objective of the Camp Roberts Environmental Studies Program is to prepare a comprehensive Biological Assessment of themore » effects of all NGB-authorized activities (includes military training, anticipated construction projects, repair and maintenance activities, and all NGB-authorized non-military activities such as hunting and fishing programs, grazing leases, etc.) on San Joaquin kit fox. The program also provides NGB with the scientific expertise necessary to insure compliance with the Endangered Species Act. The specific objective of this report is to summarize progress and results of the Environmental Studies Program made during Fiscal Years 1989 and 1990 (FY89/90). 32 refs., 9 figs., 14 tabs.« less

Meet EPA Scientist Robert Devlin, Ph.D.

EPA Pesticide Factsheets

EPA scientist Dr. Robert Devlin's main research interest is understanding the health effects of air pollution. His research characterizes the effects that inhaled substances, such as air pollutants, have on human pulmonary and cardiovascular health

24. Historic American Buildings Survey Robert W. Kerrigan Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

24. Historic American Buildings Survey Robert W. Kerrigan - Photographer Photo Taken: May 13, 1936 VIEW FROM RIGHT SIDE - SOUTH - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

43. Historic American Buildings Survey Robert W. Kerrigan Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

43. Historic American Buildings Survey Robert W. Kerrigan - Photographer Photo Taken: May 14, 1936 GENERAL VIEW TOWARD FRONT ENTRANCE - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

31. Historic American Buildings Survey Robert W. Kerrigan Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

31. Historic American Buildings Survey Robert W. Kerrigan - Photographer Photo Taken: May 14, 1936 DETAIL OF FONT (Original) - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

22. Historic American Buildings Survey Robert W. Kerrigan, Photographer Photo ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. Historic American Buildings Survey Robert W. Kerrigan, Photographer Photo Taken: May 13, 1936 VIEW FROM EAST - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

44. Historic American Buildings Survey Robert W. Kerrigan Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

44. Historic American Buildings Survey Robert W. Kerrigan - Photographer Photo Taken: May 14, 1936 COLUMN AND PULPIT DETAIL - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

45. Historic American Buildings Survey Robert W. Kerrigan Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

45. Historic American Buildings Survey Robert W. Kerrigan - Photographer Photo Taken: May 14, 1936 COLUMN AND WINDOW DETAIL - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

21. Historic American Buildings Survey Robert W. Kerrigan, Photographer Photo ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

21. Historic American Buildings Survey Robert W. Kerrigan, Photographer Photo Taken: May 14, 1936 VIEW FROM NORTH - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

ZERO-G - Crippen, Robert L.

NASA Image and Video Library

1979-04-03

Zero-gravity experiments in KC-135 conducted by John Young, Robert L. Crippen, Joseph Kerwin, and Margaret Seddon. 1. Kerwin, Joseph - Zero-G 2. Seddon, Margaret - Zero-G 3. Young, John - Zero-G 4. Aircraft - KC-135

U.S. Environmental Protection Agency's Robert S. Kerr Environmental Research Center, Ada, Oklahoma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farrar-Nagy, S.; Voss, P.; Van Geet, O.

2006-10-01

U.S. EPA's Robert S. Kerr Environmental Research Center, Ada, Oklahoma, has reduced its annual energy consumption by 45% by upgrading its building mechanical system and incorporating renewable energy.

Glycoprotein Biomarkers for the Early Detection of Aggressive Prostate Cancer — EDRN Public Portal

Cancer.gov

The Early Detection Research Network of the NCI is charged with the discovery, development and validation of biomarkers for early detection and prognosis related to neoplastic disease. Our laboratory is an NCI EDRN (U01CA152813) working on "Glycoprotein biomarkers for the early detection of aggressive prostate cancer". This EDRN administratiVE! supplement is a collaboration with Robert Veltri on his project to identify men with very low risk (indolent) prostate cancer (CaP) at the diagnostic biopsy at selection for active surveillance (AS). We will assess biopsy tissue using quantitative nuclear histomorphometric measurements and molecular biomarkers to predict an unexpected catastrophic CaP in such men with indolent CaP. At Johns Hopkins Hospital w1e use the Epstein criteria that includes; PSA density (PSAD) <0.15 ng/mVcm3, Gleason score SS, S2 cons involved with cancer, and ::;;SO% of any core involved with cancer to select AS. Our approach will study 140 AS men (70 with a expected outcome and 70 with a disastrous outcome) using nuclear histomorphometry and pre-qualified biomarkers quantified by digital microscopy. Previously, our laboratory combined measurements of DNA content and (-2)pPSA in the serum and (-5,-?)pPSA in biopsy tissue to identify 7/10 men that would fail surveillance based on the primary diagnostic biopsy. We now will devHiop a clinical, morphological and biomarker 'signature' for identifying severe aggressive disease from a AS diagnostic biopsy. Our approach will combine nuclear morphometry measured by digital microscopy with a unique biopsy tissue biomarker profile (DNA content, Ki67, Her2neu, CACND1 and periostin). Fc•r the molecular targets we will us•e a multiplex tissue blot (MTB) immunohistochemistry method. The Aims o'f our work include 1) to utilize retrospective archival biopsy material from 70 AS cases where the outcome was unexpected and disastrous and collect an equal number of AS cases (n=140) and perform assays for morphology and biomarker targi ts proposed, 2) and predict failure using Cox proportional hazards statistical modeling.

A concurrent resolution calling on the President and the allies of the United States to raise in all appropriate bilateral and multilateral fora the case of Robert Levinson at every opportunity, urging Iran to fulfill their promises of assistance to the family of Robert Levinson, and calling on Iran to share the results of its investigation into the disappearance of Robert Levinson with the Federal Bureau of Investigation.

THOMAS, 111th Congress

Rep. Wexler, Robert [D-FL-19

2009-02-03

Senate - 11/18/2009 Placed on Senate Legislative Calendar under General Orders. Calendar No. 214. (All Actions) Tracker: This bill has the status Agreed to in HouseHere are the steps for Status of Legislation:

Cultural Resources Survey and Testing Along Ditch 19 Dunklin and Stoddard Counties, Missouri

DTIC Science & Technology

1987-07-15

AD-A265 021 I/ A CULTURAL RESOURCES SURVEY AND TESTING (I ALONG DITCH 19 DUNKLIN AND STODDARD COUNTIES , MISSOURI by Kathryn A. King and * viy Robert...and Stoddard Counties , MO C 53-7103-7-545 6. AUTHOR(S) Kathryn A. King Robert H. Lafferty III 7. PERFORM•!NG ORGANIZATION NAME•S) AND ADDRESS’ES) 8...CULTURAL RESOURCES SURVEY AND TESTING ALONG DITCH 19 DUNKLIN AND STODDARD COUNTIES , MISSOURI by Kathryn A. King and Robert H. Lafferty III 1EL E C T

Promoting medical innovation while developing sound social and business policy: a conversation with Thomas G. Roberts. Interview by Barbara J. Culliton.

PubMed

Roberts, Thomas G

2008-01-01

The development of "targeted biologics" as cancer therapy has made the field ripe for investment from the private sector and is changing the face of cancer medicine, while also raising important policy concerns about price, profit, and continued innovation. In this interview Barbara Culliton talks with Thomas Roberts, who sees this world from a unique perspective. Roberts, an oncologist, has practiced at the Massachusetts General Hospital and is currently thinking about innovation as a hedge fund manager.

A Comparison of the Operational Art of George Gordon Meade and Robert Edward Lee during the Period June 1863, to March 1864.

DTIC Science & Technology

1988-03-29

PERIOD COVERED A Comparison of the Operational Art of George G. Meade and Robert E. Lee During the Period Jun 1 8 6 3 Indiv study project to March...publication until it has been cleared by the appropriate military Service er gover"uent aency. A Comparison Of The Operational Art Of George Gordon...and/or Dis Speclal;! Sp ABSTRACT AUTHOR: THOMAS A. GREEN, LTC, AV. TITLE: A Comparison of the Operational Art of George Gordon Meade and Robert Edward

Buzzard Island Dredged Material Beneficial Use Access Road, Upper Mississippi River, River Mile 349, Pool 20. General Design Memorandum and Environmental Assessment

DTIC Science & Technology

1988-06-01

contact the above number for more information. DOW E. PROUTY. PRESIDENT * ROBERT C. MESKIMEN , PRESIDENT-ELECT UO E I. S TH sl’w KENNETH W. MCNICHOLS...the Mississippi River. Cofesburg. Iowa Members of the Iowa Limestone Producers Association ROBERT C. MESKIMEN Marlin Marietta Aggregates very strongly...cc: Missouri DOC (Farabee, Dieffenbach) ITUW L7f DOW E. PROUTY. PRESIDENT 0 ROBERT C. MESKIMEN . PRESIDENT-ELECT I uSre r/m $111 KENNETH W. McNICHOLS

Index of National Aviation Facilities Experimental Center Technical Reports 1972-1977.

DTIC Science & Technology

1981-05-01

EVALUATION OF DIGITAL ALTIMETER SETTING INDICATORS Robert Frack , Ernest E. Sch’atter and Jack Bernstein Final, August 1975 55 P. (RD-75-81) (AD A013 994...runway would change the surface friction of that runway. The method consisted of jetting water at high velocity to hydraulically remove the rubber from...77-49 Erikson, Robert H. 74-17 Feher, Ray E. 76-53; 77-22 Fisher, Donald A. 74-24; 75-48; 76-15 Fisher, John J. 73-41 Frack , Robert 74-46 Gallagher

DefenseLink Special: Travels with Gates, January 2007

Science.gov Websites

that has been achieved there, said Defense Secretary Robert M. Gates. Story Gates to Build on Success , and Defense Secretary Robert M. Gates wants to build on those successes. Story Afghan Army Makes

47. Historic American Buildings Survey Robert W. Kerrigan Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

47. Historic American Buildings Survey Robert W. Kerrigan - Photographer Photo Taken: May 14, 1936 DETAIL OF ARCH - RIGHT SIDE ALTAR - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

48. Historic American Buildings Survey Robert W. Kerrigan Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

48. Historic American Buildings Survey Robert W. Kerrigan - Photographer Photo Taken: May 14, 1936 DETAIL OF ARCH - RIGHT SIDE ALTAR - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

50. Historic American Buildings Survey Robert W. Kerrigan Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

50. Historic American Buildings Survey Robert W. Kerrigan - Photographer Photo Taken: May 15, 1936 DETAIL OF SMALL CHAPEL (Not original) - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

46. Historic American Buildings Survey Robert W. Kerrigan, Photographer Photo ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

46. Historic American Buildings Survey Robert W. Kerrigan, Photographer Photo Taken: May 14, 1936 DETAIL OF ARCH LEFT SIDE - ALTAR - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

23. Historic American Buildings Survey Robert W. Kerrigan Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. Historic American Buildings Survey Robert W. Kerrigan - Photographer Photo Taken: May 14, 1936 GENERAL VIEW FROM LEFT SIDE - WEST - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

42. Historic American Buildings Survey Robert W. Kerrigan Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

42. Historic American Buildings Survey Robert W. Kerrigan - Photographer Photo Taken: May 14, 1936 GENERAL VIEW OF INTERIOR - TOWARD ALTAR - Mission San Carlos Borromeo, Rio Road & Lausen Drive, Carmel-by-the-Sea, Monterey County, CA

Modernizing the Military Retirement System

DTIC Science & Technology

2011-05-01

Patrick Gross, David Langstaff, Philip Odeen, Mark Ronald, Robert Stein, and Jack Zoeller. Catherine Whittington served as the Board Staff Analyst...Chair) Patrick Gross David Langstaff Philip Odeen Mark Ronald Robert Stein Jack Zoeller DBB Staff Analyst Catherine Whittington Methodology

33. Historic American Buildings Survey Robert W. Kerrigan, Photographer Dec. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

33. Historic American Buildings Survey Robert W. Kerrigan, Photographer Dec. 11, 1936 MONUMENT IN OLD CEMETERY (THE OLDEST MARKED GRAVE) - Mission San Francisco de Asis, Mission & Sixteenth Streets, San Francisco, San Francisco County, CA

Total Army Analysis Supporting Maximization of National Resources

DTIC Science & Technology

2013-03-01

Robert M. Mundell Department of Command Leadership and Management 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY...Colonel Robert M. Mundell Department of Command Leadership and Management Project Adviser This manuscript is submitted in partial fulfillment

Annotated Bibliography of the Air Force Human Resources Laboratory Technical Reports - 1978

DTIC Science & Technology

1980-06-01

selection of incentives for classroom use. Grade-related and non -grade-related incentives were described in this experiment in a manner designed to...information monitoring- feedback. The current piractice= materials and methods are an outgroiuth of experimental aJpproache-s to the design . dev...operated in a stand- alone mode, the R & M model can be utilized to analyze the impact of various avionics design configurations on system support

An Evaluation Report: i3 Development Grant Dev07--Sammamish High School. "Re-Imagining Career and College Readiness: STEM, Rigor, and Equity in a Comprehensive High School"

ERIC Educational Resources Information Center

Knuth, Randy; Sutton, Paul S.; Levias, Sheldon; Kuo, Annie Camey; Callison, Matthew

2016-01-01

The purpose of this study is to describe and examine the structures and policies a public, comprehensive high school put in place to implement problem-based learning (PBL) across content areas. Starting in 2010, the school implemented PBL in the hopes of increasing students' career and college readiness skills. The research took place at a…

Field Organizations: Unit Status Reporting

DTIC Science & Technology

2001-11-15

3 15 PSYOP DEV DET Detachment CDR 12/8 15 TAC PSYOP DET Detachment CDR 13/8 15 TAC PSYOP team Team leader 5/3 15 UAV TBD TBD 16 MAV/ IAV TBD TBD 16 Fox...AR 600–110 Identification, Surveillance, and Administration of Personnel Infected with Human Immuno-deficiency Virus (HIV) AR 601–210 Regular Army...HIV human immunodeficiency virus HMMWV high mobility multipurpose wheeled vehicle HO hospitalized/convalescent leave category of personnel non

CVN 78 Gerald R. Ford Class Nuclear Aircraft Carrier (CVN 78)

DTIC Science & Technology

2013-12-01

Capabil... -Follow-on Ship (CVN 79) DAB Program Review - • Start Construction - • Delivery .-:K IOT &E IOT &E Start .-:41 IOT &E Complete e(41 Follow-on...Ship (CVN 80) DAB Program Review -Platform-Level Integration D ... ....., Milestone C .. EMALS EMALS Delivery (with Ship) .-:o; IOC ..:<! IOT ...E IOT &E Start ..:<! IOT &E Complete -· Platform-Level Integration .. ...:<! CVN 78 Milestones SAR Baseline Dev Est Current APB Development

Zebrafish as a Model to Study NF1-Associated Learning Deficits

DTIC Science & Technology

2015-05-01

deficit - hyperactivity disorder . Dev. Med. Child Neurol. 48, 973–977. Isenberg, J.C., Templer, A., Gao, F., Titus, J.B., and Gutmann, D.H. (2013). Attention ...dominant disorder associated with attention deficits and learning disabilities. The primary known function of neurofibromin, encoded by the NF1 gene, is...develop cognitive deficits . The disorder is caused by mutations in a gene neurofibromin. In normal individuals, neurofibromin regulates the activity

Performance of High Voltage Modules Under Abuse Operations

NASA Technical Reports Server (NTRS)

Jeevarajan, Judith A.; Darcy, Eric C.; Irlbeck, Bradley W.

2005-01-01

The Electric Auxiliary Power Unit (EAPU) or the Advanced Hydraulic Power System (AHPS) is a Shuttle Upgrade program. Of the two battery design approaches that were considered in support of this program, the current paper concentrates on the testing performed on the small-cell approach. Testing performed at both ComDev Space, Canada and at NASA-JSC is described in this paper. Testing included those under mission profile conditions and off-nominal abusive conditions.

Analysis of United Nations Millennium Summit Speeches

DTIC Science & Technology

2001-04-01

Development 36 46 Taiwan 14 16 Terrorism 32 60 Transnational Crime 31 40 Urban-Rural 2 12 War 65 108 Water 15 20 Weapons 36 62 Women/ Gender ...Concept Number of Countries Freq. of Mention Governance 47 59 Aid/Assistance for Dev. 44 58 Sovereignty 36 53 Women/ Gender Equality 38 50...take into consideration how different cultures consider the special status of elders and gender responsibilities. Social stability has to be considered

Histone Methylation and Epigenetic Silencing in Breast Cancer

DTIC Science & Technology

2008-07-01

Curr Opin Genet Dev 14(2): 155-164. Caretti, G ., Di Padova, M., Micales, B., Lyons, G.E., and Sartorelli, V. 2004. The Polycomb Ezh2...tissues. Cancer Res 66(8): 4095-4099. Egger, G ., Liang, G ., Aparicio, A., and Jones, P.A. 2004. Epigenetics in human disease and prospects for...Widschwendter, M., Fiegl, H., Egle, D., Mueller-Holzner, E., Spizzo, G ., Marth, C., Weisenberger, D.J., Campan, M., Young, J., Jacobs, I., and Laird

Transforming Growth Factor-B Receptors in Human Breast Cancer.

DTIC Science & Technology

1998-05-01

I., Polyak, K., Iavarone, A., and Massagud, J. Kip/ Cip and Ink4 cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-ß. Genes Dev...specimens. Thirdly, we have developped transient transfection assays to determine how specific TßR mutations affect affect receptor function. Using...Growth Factor-ß (TGFß) is the most potent known inhibitor of cell cycle progression of normal mammary epithelial cells; in addition, it causes cells

EGFR Activation by Spatially Restricted Ligands

DTIC Science & Technology

2006-06-01

the level of ligand production, that result in human breast cancer. We have integrated genetic and biochemical methods to study (1) the effects of a...and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis. Genes Dev 12, 2711-2723...findings contained in this report are those of the author(s) and should not be construed as an official Department of the Army position, policy or decision

Standard Port-Visit Cost Forecasting Model for U.S. Navy Husbanding Contracts

DTIC Science & Technology

2009-12-01

Protocol (HTTP) server.35 2. MySQL . An open-source database.36 3. PHP . A common scripting language used for Web development.37 E. IMPLEMENTATION OF...Inc. (2009). MySQL Community Server (Version 5.1) [Software]. Available from http://dev.mysql.com/downloads/ 37 The PHP Group (2009). PHP (Version...Logistics Services MySQL My Structured Query Language NAVSUP Navy Supply Systems Command NC Non-Contract Items NPS Naval Postgraduate

Technologies for Energy from Biomass by Direct Combustion, Gasification, and Liquefaction.

DTIC Science & Technology

1981-05-01

1980 1982 1984 Development Alberta Industrial Dev. X American Fyr. Feeder X Andco, Inc. X Applied Engineering Co., Inc. X Biomass Corp. X Bio-Solar x...Feeder ANDCO, Inc. Applied Engineering Company Biomass Corporation Bio-Solar Research and Development Corporation Combustion Power Company, Inc. Davy...Andco. Inc. X Applied Engineering Co., Inc. X Biomass Corp. X , Big-Solar .X I Combustion Power .. XI Davy Powergas X j Dekalb Acresearch, Inc.- x Duvant

Autism Diagnostic Interview-Revised (ADI-R) Algorithms for Toddlers and Young Preschoolers: Application in a Non-US Sample of 1,104 Children

ERIC Educational Resources Information Center

de Bildt, Annelies; Sytema, Sjoerd; Zander, Eric; Bölte, Sven; Sturm, Harald; Yirmiya, Nurit; Yaari, Maya; Charman, Tony; Salomone, Erica; LeCouteur, Ann; Green, Jonathan; Bedia, Ricardo Canal; Primo, Patricia García; van Daalen, Emma; de Jonge, Maretha V.; Guðmundsdóttir, Emilía; Jóhannsdóttir, Sigurrós; Raleva, Marija; Boskovska, Meri; Rogé, Bernadette; Baduel, Sophie; Moilanen, Irma; Yliherva, Anneli; Buitelaar, Jan; Oosterling, Iris J.

2015-01-01

The current study aimed to investigate the Autism Diagnostic Interview-Revised (ADI-R) algorithms for toddlers and young preschoolers (Kim and Lord, "J Autism Dev Disord" 42(1):82-93, 2012) in a non-US sample from ten sites in nine countries (n = 1,104). The construct validity indicated a good fit of the algorithms. The diagnostic…

Investigation of Radiation Effects on Semiconductor Devices and Integrated Circuits

DTIC Science & Technology

1988-09-16

qualitativelysimilar to, and consistent with, findings at the two higher energies .) Results for irradiation of eightwhere q is the electronic charge, ni is the...COMMUNICATIONS R&D COMMAND ATTN: R BROWN ASSISTANT TO THE SECRETARY OF DEFENSE ATOMIC ENERGY U S ARMY ELECTRONIC TECH DEV LAB ATTN: EXECUTIVE ASSISTANT...Continue on reverse if necessary and identify by block number) Results of a study of radiation effects on electronic materials, devices, and integrated

Deciphering the balkan Enigma: Using History to Inform Policy

DTIC Science & Technology

1993-03-01

University Press, 1973. After long experience with German interference in Serbian/Yugoslav affairs (1878, 1908, 1914 - 1918 ) it should not be surprising that... 1914 - 1918 , ed. Djordjevicý, Santa Barbara: CLID Books, 1980. 151. James Gow, "Deconstructing Yugoslavia," Survival, Vol. 33, Nc. 4, July-August 1992, p...of political institutions witnin tine Balkans anu io0w these political dev, ’ýpments intluence current events. Historical perspective gained is used

The Autism Diagnostic Observation Schedule--Toddler Module: A New Module of a Standardized Diagnostic Measure for Autism Spectrum Disorders

ERIC Educational Resources Information Center

Luyster, Rhiannon; Gotham, Katherine; Guthrie, Whitney; Coffing, Mia; Petrak, Rachel; Pierce, Karen; Bishop, Somer; Esler, Amy; Hus, Vanessa; Oti, Rosalind; Richler, Jennifer; Risi, Susan; Lord, Catherine

2009-01-01

The Autism Diagnostic Observation Schedule (ADOS; Lord et al., J Autism Dev Disord, 30(3):205-223, 2000) is widely accepted as a "gold standard" diagnostic instrument, but it is of restricted utility with very young children. The purpose of the current project was to modify the ADOS for use in children under 30 months of age. A modified ADOS, the…

Simulation-Based Learning: Workshops for Researchers and Educators in the Western United States, and the Pacific Rim

DTIC Science & Technology

2007-03-01

Artificial Intelligence Walter Greenleaf, Greenleaf Medical Applications in Rehabilitation Medicine Workshop 4: 12/14-5/07 SUMMIT/TATRC...Applications in Medicine; 1-day Long Beach, CA – MMVR 118 people 1/25/05 2 MEDICAL-SURGICAL TRAINING WITH VIDEOGAMES ; ½-day Portland, OR...for Modeling Virtual Patients Parvati Dev " Intelligent " characters in Virtual World Lou Halamek, Stanford Debriefing- After Action Review

Performance Evaluation of Kitchen Exhaust Draft Hoods.

DTIC Science & Technology

1980-03-01

1-ACI827 JOHNS - MANVILLE SALES CORP DENVER CO RESEARCH AND DEV-ETC F/e 13/1 PERFORMANCE EVALUATION OF KITCHEN EXHAUST DRAFT HOOOS. (U) MAR 80 P 8...ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT PROJECT. TASK AREA a WOPK UNIT NUMOERS Johns - Manville Sales Corper a, t Research & Development Center /0004...P. B. SHEPHERD, R. H. NEISEL JOHNS - MANVILLE SALES CORPORATION RESEARCH & DEVELOPMENT CENTER KEN-CARYL RANCH, DENVER, COLORADO 80217 MARCH 1980 FINAL

How to Be a Better Consumer of Security Maturity Models

DTIC Science & Technology

2014-10-21

Health Care wellcent1ve Health Care Network !Maturity IModel: Posted on July 15, 2013 by Paul D. Taylor, M.D., CMIO, Wellcentive, Inc. Time and...expectations and delivery are aligned 10 DevOps Collaboration Automation Process Initial ( Defined Measured 11 Marketing A ih ’ f·, )j ,lcp... networked systems CERT – Anticipating and solving our nation’s cybersecurity challenges • Largest technical program at SEI • Focused on internet

Ukraine: dismissal on the basis of HIV status ruled unconstitutional.

PubMed

Bordunis, Tetyana

2005-04-01

On 18 October 2004 the Novosanzhary District Court in Poltava oblast ruled in favour of Olexiy Voloshyn, who had been harassed and fired by his employer on the basis of his HIV status. The court held that Voloshyn's constitutional rights to equality in choice of profession and labour activity, and respect for human honour and dignity, had been violated by Viktoriya Dev'yatko, editor-in-chief of the Novosanzhary district newspaper.

US EPA Freedom of Information Act Workgroup Report: Prepared for Robert Perciasepe, Deputy Administrator

EPA Pesticide Factsheets

Deputy Administrator Robert Perciasepe requested a workgroup develop options and recommendations to ensure that the Agency’s administration of FOIA and related processes are effective, efficient and promote open government and transparency policies.

Siegfried Receives 2006 Robert C. Cowen Award

NASA Astrophysics Data System (ADS)

Siegfried, Tom

2006-07-01

Tom Siegfried received the 2006 Robert C. Cowen Award for Sustained Achievement in ScienceJournalism at the Joint Assembly Honors Ceremony, which was held on 25 May 2006 inBaltimore, Md. The award honors lifetime achievement in science journalism.

Developing Strategic Leader Competencies in Today’s Junior Officer Corps

DTIC Science & Technology

2013-03-01

AND ADDRESS(ES) Colonel Robert M. Mundell Department of Command, Leadership, and Management 8. PERFORMING ORGANIZATION REPORT NUMBER 9...O’Donnell United States Army Colonel Robert M. Mundell Department of Command, Leadership, and Management Project Adviser

Selected Proceedings from the Texas Foreign Language Education Conference 2001.

ERIC Educational Resources Information Center

Luke, Christopher, Ed.

2001-01-01

This collection of papers includes: "Language Learning Motivation: The Student, the Teacher, and the Researcher" (Robert C. Gardner); "The Self-Reported Perspectives Regarding Academic Writing among Taiwanese Graduate Students Specializing in TEFL" (Robert Johanson); "Contradictions, Appropriation, and Transformation: An…

A Constructive Induction Approach to Computer Immunology

DTIC Science & Technology

1999-03-01

LVM98] Lamont, Gary B., David A. Van Veldhuizen , and Robert E Marmelstein, A Distributed Architecture for a Self-Adaptive Computer Virus...Artificial Intelligence, Herndon, VA, 1995. [MVL98] Marmelstein, Robert E., David A. Van Veldhuizen , and Gary B. Lamont. Modeling & Analysis

75 FR 72935 - Apricots Grown in Designated Counties in Washington; Temporary Relaxation of the Minimum Grade...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-29

... FURTHER INFORMATION CONTACT: Robert J. Curry or Gary D. Olson, Northwest Marketing Field Office, Marketing...: (503) 326-7440, or E-mail: Robert.Curry@ams.usda.gov or [email protected] . Small businesses may...

78 FR 56227 - Issuance of an Experimental Use Permit

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-12

... experimental use permit (EUP) to the pesticide applicant, Robert I. Rose, Ph.D., on behalf of James Mains, Ph.D.... Issuance. Robert I. Rose, Ph.D., on behalf of James Mains, Ph.D., Mosquito Mate, Inc., 1122 Oak Hill Drive...

Balancing Petroleum Force Structure/Capabilities between Active and Reserve Components

DTIC Science & Technology

2013-03-01

ORGANIZATION NAME(S) AND ADDRESS(ES) Colonel Robert M. Mundell Department of Command, Leadership, and Management 8. PERFORMING ORGANIZATION REPORT...Colonel Kenneth R. Hook United States Army Colonel Robert M. Mundell Department of Command, Leadership, and Management Project

Max Weber and Robert Michels.

ERIC Educational Resources Information Center

Scaff, Lawrence A.

1981-01-01

This paper investigates the unique intellectual partnership of Max Weber and Robert Michels, with particular emphasis on Weber's influence on Michel's inquiry into the sociology of parties and organization. Concludes with an evaluation of the import of Weber's critique of Michels' work. (DB)

75 FR 61985 - Airworthiness Directives; Boeing Model 747-100, 747-100B, 747-100B SUD, 747-200B, 747-200F, 747...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-07

... docket shortly after receipt. FOR FURTHER INFORMATION CONTACT: Robert Kaufman, Aerospace Engineer, Cabin.... Send information to Robert Kaufman, Aerospace Engineer, Cabin Safety and Environmental Systems Branch...

78 FR 45548 - South Dakota; Major Disaster and Related Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-29

... President issued a major disaster declaration under the authority of the Robert T. Stafford Disaster Relief... warrant a major disaster declaration under the Robert T. Stafford Disaster Relief and Emergency Assistance...; 97.048, Disaster Housing Assistance to [[Page 45549

The role of water vapor in the ITCZ response to hemispherically asymmetric forcings

NASA Astrophysics Data System (ADS)

Clark, S.; Ming, Y.; Held, I.

2016-12-01

Studies using both comprehensive and simplified models have shown that changes to the inter-hemispheric energy budget can lead to changes in the position of the ITCZ. In these studies, the mean position of the ITCZ tends to shift toward the hemisphere receiving more energy. While included in many studies using comprehensive models, the role of the water vapor-radiation feedback in influencing ITCZ shifts has not been focused on in isolation in an idealized setting. Here we use an aquaplanet idealized moist general circulation model initially developed by Dargan Frierson, without clouds, newly coupled to a full radiative transfer code to investigate the role of water vapor in the ITCZ response to hemispherically asymmetric forcings. We induce a southward ITCZ shift by reducing the incoming solar radiation in the northern hemisphere. To isolate the radiative impact of water vapor, we run simulations where the radiation code sees the prognostic water vapor field, which responds dynamically to temperature, parameterized convection, and the circulation and also run simulations where the radiation code sees a prescribed static climatological water vapor field. We find that under Earth-like climate conditions, a shifting water vapor distribution's interaction with longwave radiation amplifies the latitudinal displacement of the ITCZ in response to a given hemispherically asymmetric forcing roughly by a factor of two; this effect appears robust to the convection scheme used. We argue that this amplifying effect can be explained using the energy flux equator theory for the position of the ITCZ.

Expression of multiple Src family kinases in sea urchin eggs and their function in Ca2+ release at fertilization.

PubMed

Townley, Ian K; Schuyler, Erin; Parker-Gür, Michelle; Foltz, Kathy R

2009-03-15

Egg activation at fertilization in deuterostomes requires a rise in intracellular Ca(2+), which is released from the egg's endoplasmic reticulum. In sea urchins, a Src Family Kinase (SpSFK1) is necessary for the PLCgamma-mediated signaling event that initiates this Ca(2+) release (Giusti, A.F., O'Neill, F.J., Yamasu, K., Foltz, K.R. and Jaffe, L.A., 2003. Function of a sea urchin egg Src family kinase in initiating Ca2+ release at fertilization. Dev. Biol. 256, 367-378.). Annotation of the Strongylocentrotus purpuratus genome sequence led to the identification of additional, predicted SFKs (Bradham, C.A., Foltz, D.R., Beane, W.S., Amone, M.I., Rizzo, F., Coffman, J.A., Mushegian, A., Goel, M., Morales, J., Geneviere, A.M., Lapraz, F., Robertson, A.J., Kelkar, H., Loza-Coll, M., Townley, I.K., Raisch, M., Roux, M.M., Lepage, T., Gache, C., McClay, D.R., Manning, G., 2006. The sea urchin kinome: a first look. Dev. Biol. 300, 180-193.; Roux, M.M., Townley, I.K., Raisch, M., Reade, A., Bradham, C., Humphreys, G., Gunaratne, H.J., Killian, C.E., Moy, G., Su, Y.H., Ettensohn, C.A., Wilt, F., Vacquier, V.D., Burke, R.D., Wessel, G. and Foltz, K.R., 2006. A functional genomic and proteomic perspective of sea urchin calcium signaling and egg activation. Dev. Biol. 300, 416-433.). Here, we describe the cloning and characterization of these 4 additional SFKs and test their function during the initial Ca(2+) release at fertilization using the dominant-interfering microinjection method coupled with Ca(2+) recording. While two of the new SFKs (SpFrk and SpSFK3) are necessary for Ca(2+) release, SpSFK5 appears dispensable for early egg to embryo transition events. Interestingly, SpSFK7 may be involved in preventing precocious release of Ca(2+). Binding studies indicate that only SpSFK1 is capable of direct interaction with PLCgamma. Immunolocalization studies suggest that one or more SpSFK and PLCgamma are localized to the egg cortex and at the site of sperm-egg interaction. Collectively, these data indicate that more than one SFK is involved in the Ca(2+) release pathway at fertilization.

Gene expression of matrix metalloproteinases and LH receptors in mare follicular development.

PubMed

Bastos, H B A; Kretzmann, N A; Santos, G O; Esmeraldino, A T; Rechsteiner, S Fiala; Mattos, R C; Neves, A P

2014-11-01

The period from the emergence of a dominant follicle until its formation requires tissue remodeling. Enzymes promoting collagen lysis, such as matrix metalloproteinases (MMPs), are fundamental for the process of extracellular matrix remodeling, which allows changes in ovarian tissue architecture during follicular growth. It has been suggested that the production of these enzymes may be affected by the rise in circulating concentrations of LH, which acts on the ovarian surface epithelium (OSE). The aim of this study was to determine the expression of MMP-1, MMP-2, and LH receptor (LHR) in the ovulation fossa and in the central portion of the equine ovary during follicular deviation and dominance. Ovaries of 12 cyclic mares were selected and subsequently divided into two groups: development (DEV) group and dominant (DOM) group. The DEV group consisted of ovaries from six animals whose follicles were less than 28 mm in diameter (follicular deviation), and the DOM group consisted of ovaries from six animals whose follicles measured 28 mm or more in diameter (dominant follicles). The latter group was divided into two subgroups: the group of ovaries with a dominant follicle (DOM-D) and the group of contralateral ovaries (DOM-C). Our results showed that mRNA for MMP-1, MMP-2, and LHR was present in the equine ovary during follicle development, in the ovulation fossa, and in the central portion of the ovary. MMP-1 and LHR gene expression was greater (P < 0.05) for the DOM-D group compared with the DOM-C group. In the DOM-D group, MMP-1, MMP-2, and LHR gene expression was greater (P < 0.05) in the ovarian stroma compared with the ovulation fossa. Using immunohistochemistry, OSE from the DOM group showed increased expression compared with the DEV group (P < 0.05). In conclusion, we demonstrated that MMP-1 and MMP-2 might be fundamental for events related to tissue remodeling, which occurs during follicular development until the formation of the dominant follicle. We also demonstrated the relationship between the gene expression of MMPs and the gene and protein expression of LHR, suggesting that LHR in the OSE might be an important factor to initiate the signaling cascade that culminates with the production of MMPs. Copyright © 2014 Elsevier Inc. All rights reserved.

NASA Acting Administrator Robert Lightfoot All Hands

NASA Image and Video Library

2017-08-15

At NASA's Kennedy Space Center in Florida, agency Acting Administrator Robert Lightfoot and Deputy Associate Administrator Lesa Roe speak to employees during a town hall meeting in the conference room of Operations Support Building II. During the gathering, they updated progress on NASA programs.

Q & A with Ed Tech Leaders: Interview with Robert Talbert

ERIC Educational Resources Information Center

Shaughnessy, Michael F.; Yan, Juchao

2015-01-01

In this regular feature of "Educational Technology," Michael F. Shaughnessy and Juchao Yan present their interview with Robert Talbert, Associate Professor, Mathematics Department, Grand Valley State University, Allendale, Michigan. Their interview centered around thirteen questions that professor Talbert provided enlightening responds…

Morchella MLST database

USDA-ARS?s Scientific Manuscript database

Welcome to the Morchella MLST database. This dedicated database was set up at the CBS-KNAW Biodiversity Center by Vincent Robert in February 2012, using BioloMICS software (Robert et al., 2011), to facilitate DNA sequence-based identifications of Morchella species via the Internet. The current datab...

Mission, Science, and Race in South Africa; AW Roberts of Lovedale 1883-1938

NASA Astrophysics Data System (ADS)

Glass, I.S.

2016-02-01

Book Review: Biography of Alexander William Roberts. Noted educator, variable star observer and politician who represented South African "natives" in the parliament of the Union of South Africa at a time when they had no other representation.

76 FR 62085 - Pennsylvania; Major Disaster and Related Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-06

... Robert T. Stafford Disaster Relief and Emergency Assistance Act, 42 U.S.C. 5121 et seq. (the ``Stafford... severity and magnitude to warrant a major disaster declaration under the Robert T. Stafford Disaster Relief....046, Fire Management Assistance Grant; [[Page 62086

Robert Frost and the Poetry of Physics.

ERIC Educational Resources Information Center

Coletta, W. John; Tamres, David H.

1992-01-01

Examines five poems by Robert Frost that illustrate Frost's interest in science. The poems include allusions to renowned physicists, metaphoric descriptions of some famous physics experiments, explorations of complementarity as enunciated by Bohr, and poetic formulations of Heisenberg's uncertainty principle. (20 references) (MDH)

2. Historic American Buildings Survey Robert J. Kelley, Photographer May ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey Robert J. Kelley, Photographer May 1958 LOOKING NORTH - SHOWS SOUTH ELEVATION, MAIN HOUSE, ROOF OF NORTH ELEVATION AND WEST ELEVATION, WHOSE ROOF WAS RAISED IN RECENT TIMES - Burbank-Hatheway House, Main Street, Suffield, Hartford County, CT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Descartes, M.; Longshore, J.W.; Crawford, E.

We report an infant with double trisomy 48,XXX,+18, who also displayed features of Roberts syndrome. All previously published cases with similar double trisomy have presented with features of trisomy 18 syndrome. The chromosome analysis done at birth revealed the double trisomy; parental chromosomes were normal. The proband presented with microbrachycephaly, unilateral cleft lip and palate, choanal atresia, midfacial capillary hemanioma, thin nares, shallow orbits, malformed ears, sparse hair, hypomelia of the upper limbs, rocker-bottom feet, auricular septal defect and agenesis of the corpus callosum. Characteristic features of Roberts syndrome included hypomelia, midfacial defects, and severe growth deficiency. Among the manymore » different features reported in the literature for patients with trisomy 18 syndrome, the most consistent were growth deficiency, clenched fingers and congenital heart defects (e.g. VSD, ASD, PDA). Although some of our patient`s features such as cleft lip and cleft palate, low-set malformed ears, ASD, defects of the corpus callosum, choanal atresia, radial aplasia could also be seen in trisomy 18 syndrome (in 10-50% of the cases), her phenotype was more typical of Roberts syndrome because of symmetrical hypomelia and midfacial defects. Our patient`s chromosomes did not show premature separation of centromeric heterochromatin, a feature reported to occur in approximately one-half of individuals with Roberts syndrome. Sporadic aneuploidy involving different chromosomes has been found in lymphocyte cultures from some Roberts syndrome patients and is considered by some authors as a mitotic mutant. This aneuploidy is most likely to be chromosome gain. The simultaneous occurrence of trisomy X and 18 is extremely rare with only 11 cases having been reported in the literature. Our patient is unique since she has the double trisomy in addition to the characteristic features of Roberts syndrome.« less

Determine the Role of Canonical Wnt Signaling in Ovarian Tumorigenesis

DTIC Science & Technology

2011-10-01

oncogenic Ras. Nature, 2000. 406(6792): p. 207-10. 11 16. Kuilman, T., et al., The essence of senescence. Genes Dev, 2010. 24(22): p. 2463- 79. 17...Benjamin G. Bitler, Jasmine P. Nicodemus, Hua Li, et al. Senescence Wnt5a Suppresses Epithelial Ovarian Cancer by Promoting Cellular...Suppresses Epithelial Ovarian Cancer by Promoting Cellular Senescence Benjamin G. Bitler1, Jasmine P. Nicodemus1, Hua Li1, Qi Cai2, Hong Wu3, Xiang

A Feedforward Compensation Technique for Use in Mitigating Platform Induced Jitter

DTIC Science & Technology

2010-05-06

Mounting Screw Holes Leveling Valve (3 per system) Control Arm 72 A P P E N D I X H : L a s e r D i o d e Class 5mW, Class IIIa Typical...8217Connected’); C4 = ’Yes’ TF1 =strcmp(C1, C2);TF2=strcmp(C3, C4); if ~ TF1 ; unload(tg); load(tg,’DEV3_rev19’); tg=xpctarget.xpc; end if

Prediction Model for Impulsive Noise on Structures

DTIC Science & Technology

2012-09-01

construction usually have an interior wall finish of: a) gypsum wallboard (also called plasterboard or drywall), b) plaster or c) wood paneling... Gypsum Plaster , Wall Board 11,67 0.04 NA For simply-supported beams vibrating in their fundamental mode, the value of KS is needed for...Dev of log10(f0) for wood panel interior to be average for wood walls with plaster or gypsum board interior. (8) L(w) based on estimated standard

Field-Effect Spectroscopy of Interface States

DTIC Science & Technology

1988-12-31

ed.), Physics and Chemistry of Il-V Compound Semiconductor Interfaces, Plenum, New York, 1985, p. 327. HETEROJUNCTION AND DIELECTRICALLY INSULATED GATE...Electron Devices. voi. ED-29. pp. 1059-1064, 1982. chemistry , and physics from San Diego State Uni- 131 T. H. Mies, W. M. Paulson, and M. S...1982). 40. T. Y. Chang, R. F. Leheny, R. E. Nahory, E. Silberg , A. A. Ballman, E. A. Carid’ and C. J. Harrold, IEEE Electron. Dev. Lett. EDL- 3, 56

COX-1 Suppression and Follicle Depletion in the Etiology of Menopause-Associated Ovarian Cancer

DTIC Science & Technology

2008-10-01

form (8), and cause growth inhibition and apoptosis in ovarian cancer cell lines (9). However, the link between morphological inhibition and...of the c-kit receptor. Genes Dev 1990;4:390-400. 2. Mintz B. Embryological development of primordial germ-cells in the mouse: influence of a new...708–14. 12 Rodriguez GC, Walmer DK, Cline M, et al. Effect of progestin on the ovarian epithelium of macaques: cancer prevention through apoptosis

Eliminating NVA Requirements & Improving the Inspection System

DTIC Science & Technology

2011-01-27

Wg ISPR Blood Pgm QA JTAC Stan/Eval Formal Joint Comm AAAHC SCI Security Pgm Review Pathologists WII Ed & Dev Inter vent. Servi ces FDA Pubs...his/her tour  Balanced mix of scheduled & no-notice inspections  Units will be inspected for Readiness and Compliance every 24 months  Readiness...a whole  IG Team Chiefs drive team effectiveness, are the most visible direct representatives of MAJCOM CCs & should be selected by CIP or a board

Waste Analysis Plan and Waste Characterization Survey, Barksdale AFB, Louisiana

DTIC Science & Technology

1991-03-01

review to assess if analysis is needed, any analyses that are to be provided by generators, and methods to be used to meet specific waste analysis ...sampling method , sampling frequency, parameters of analysis , SW 846 test methods , Department of Transportation (DOT) shipping name and hazard class...S.e.iceA w/Atchs 2. HQ SAC/DEV Ltr, 28 Sep 90 19 119 APPENDIX B Waste Analysis Plan Rationale 21 APPENDIX B 1. SAMPLING METHOD RATIONALE: Composite Liquid

Revised RB 100-9: A Guide to the Formulation and Selection of Feasible Tactical Courses of Action.

DTIC Science & Technology

1981-04-23

Department of Defense ATTN: M. Minnemam U.S. Army Armament Rsch Dev & Cmd ATTN: K . Hinman ATTN: DRDAR-LCN-E ATTN: Strategic & Space Sys (OS) ATTN: F...B2590D. Is. K EY WORDS (Cmnthme an rever. side it aaeceety OWd IdentIfy by Week munst) Tactical Course of Action Defensive Operations Integrated... 12 CHAPTER 2. STEPS LOADING TO FORMULATION OF COURSES OF ACTION ..........13 Section I. Introduction

Measuring the Influence of Mainstream Media on Twitter Users

DTIC Science & Technology

2014-07-01

dataset or called from a Java code. Weka contains tools for data pre-processing, classification, regression, clustering, association rules, and...server at CAU. The command line to start Weka is: java -jar /opt/weka-3-6-9/weka.jar & The first window that appears is the Weka’s graphical user...website hosts all detailed information at the fedora website at1. We chose the 140dev streaming API to store the tweets into our fedora using MySQL

Cannon AFB, Clovis, New Mexico. Revised Uniform Summary of Surface Weather Observations (RUSSWO), Parts A-F

DTIC Science & Technology

1975-06-16

dry -bulb temperature, means and standard d~viatinne nf eirg-hiiih- wM~e-.h,lh (y DD 1473 ~ UNCLASSIFIED SECURIS- CLASSIFICATION OF THIS PAGE(Ifnon...Val. Entoted) 19. Percentqge frequency of distribution tables Dry -bulb temperature versus wet-bulb temperature Cumulative percentage frequency of...ATMOSPHERIC PHENOMENA EXTREME MAX & MIN TEMP PART B PRECIPITATION PSYCHROMETRIC- DRY VS WET BULB SNOWFALL MEAN & STD DEV - ( DRY BULB, WET BULB, & DEW

Department of Defense In-House RDT&E Activities

DTIC Science & Technology

1979-10-30

OIVAI .. I-:JNLI’IONS/EQJIPMtN’r/CAPAt3ILIrflt.4 tNC’i4PAb-Eý, APPLO RUA INCL WRC DEV AND) SPT IN INTI:RLO got: ~ISI6 ANALYSIS. JAM,IJEtPSi(7 iNrt7L...LU*. CAPT. R. 4. tsROWN TECH1.L1R. MR. THOMAS RAMIREZ F. ~PROGRAM LJATA BY FISCAL YEAR (MILLION S PiKOtRAM 1979 IQ80fk~(ACTUJAL) (ACT + EsT) TUTAL

Mechanisms of Breast Carcinogenesis Involving Wild-Type p53

DTIC Science & Technology

2001-09-01

Nelson, C. E., Gryka , M . A., Litwak, G., Gebhardt, M ., level of p53 that was expressed in the cells in both these studies Bressac, B., Ozturk, M ., Baker...14 Publication resulting from this research: 1. Resnick-Silverman, L., S. St Clair, M . Maurer, K...activation by the tumor suppressor protein p53. Genes Dev 12:2102-7. 2. Tang, H. Y., K. Zhao, J. F. Pizzolato, M . Fonarev, J. C. Langer, and J. J

Dielectric Constant and Loss Data Part 2

DTIC Science & Technology

1975-12-01

fluoride, single crystal, Melamine - formaldehyde resins , Columbia Univ., P.R.-75 IV-21,22,112; V-8,88 Manganese-magnesium ferrite, Melamine GMG, IV-2i...butylperoxy) Urea - formaldehyde resins , IV-23 hexane, P.R.-197 U.S. Army Engineering Research and War Dept., Picatinny Arsenal, see Dev. Lab., Fort...IV.-36 irradiated, P.R,-161 "Bakelite" polyvinyl chloride- "Amplifilm," IV-14; V-74 acetate, see "Vinylites" Axiiliine- formaldehyde resins , IV-21

Synthesis, Characterization, and Sensitivity Analysis of Urea Nitrate (UN)

DTIC Science & Technology

2015-04-01

of the line is the rate of the reaction for the corresponding temperature. The equations for the zero order reaction and half- life equation follow...rate law (k is rate constant; [A] is the concentration of UN) Rate = k[A]n . (1) Eq. 2 shows the half-life (t½) equation for a zero order reaction...MGMT 1 GOVT PRINTG OFC (PDF) A MALHOTRA 2 WEAPONS DEV & (PDF) INTEGRATION DIRCTRT AMRDEC RDMR WDN J NEIDERT G DRAKE

Electrochemical and Photochemical Treatment of Aqueous Waste Streams

DTIC Science & Technology

1996-01-01

TREATMENT OF AQUEOUS WASTE STREAMS Joseph C. Farmer, Richard W. Pekala, Francis T. Wang, David V. Fix, Alan M. Volpe, Daniel D. Dietrich, William H...STREAMS Joseph C. Farmer, Richard W. Pekala, Francis T. Wang, David V. Fix, Alan M. Volpe, Daniel D. Dietrich, William H. Siegel and James F. Carley...1992). Wilbourne , C. M. Wong, , W. S. Gillam, S. Johnson, R. H. Horowitz, "Electrosorb Process for Desalting Water," Res. Dev. Prog. Rept. No. 516, 16. J

Architectural Implications of DevOps

DTIC Science & Technology

2014-03-27

Project Management Approach Size Metrics Years In Use Release Cadence CI Cadence A Agile/ Scrum (last 2 years and traditional before...that) 1M SLOC 17 Client release available every 2 months (not all accept it) Daily CI build B Water/ Scrum /F all 3M SLOC, team size 6– 8...90,000 users 3+ Internal release every 2–3 weeks, external release as needed Daily CI build C Agile/ Scrum Team size 30 2+ Internal release every

SMC Systems Engineering: Specialty Engineering Disciplines Framework and Descriptions. Volume 2

DTIC Science & Technology

2011-10-03

Engineering Disciplines Updale SNiEng Planning to Meet Program Objectives 1- -----:;..._- .-----------------, I Update SIW Eng T as1<s & Timing ol T asl<s...Analyses 1-Dev SNi Eng Products e.g. Assessmenls, Rills, Certs 1- ID & Manage Resources: Tools, Equip, Skills Assess Contractors’ Compian<:e to SIW Eng...Approaches to Meet SIW Ol>jeclives S1ipulale Contraclllal Risk and Actions lot Mitigations Review Contraclors’ Tech Data (Technical & Training Manuals

Toxicogenomic response of Mycobacterium bovis BCG to peracetic acid and a comparative analysis of the M. bovis BCG response to three oxidative disinfectants.

PubMed

Nde, Chantal W; Toghrol, Freshteh; Jang, Hyeung-Jin; Bentley, William E

2011-04-01

Tuberculosis is a leading cause of death worldwide and infects thousands of Americans annually. Mycobacterium bovis causes tuberculosis in humans and several animal species. Peracetic acid is an approved tuberculocide in hospital and domestic environments. This study presents for the first time the transcriptomic changes in M. bovis BCG after treatment with 0.1 mM peracetic acid for 10 and 20 min. This study also presents for the first time a comparison among the transcriptomic responses of M. bovis BCG to three oxidative disinfectants: peracetic acid, sodium hypochlorite, and hydrogen peroxide after 10 min of treatment. Results indicate that arginine biosynthesis, virulence, and oxidative stress response genes were upregulated after both peracetic acid treatment times. Three DNA repair genes were downregulated after 10 and 20 min and cell wall component genes were upregulated after 20 min. The devR-devS signal transduction system was upregulated after 10 min, suggesting a role in the protection against peracetic acid treatment. Results also suggest that peracetic acid and sodium hypochlorite both induce the expression of the ctpF gene which is upregulated in hypoxic environments. Further, this study reveals that in M. bovis BCG, hydrogen peroxide and peracetic acid both induce the expression of katG involved in oxidative stress response and the mbtD and mbtI genes involved in iron regulation/virulence.

Not Just Horsing Around: The Impact of Equine-Assisted Learning on Levels of Hope and Depression in At-Risk Adolescents.

PubMed

Frederick, Karen E; Ivey Hatz, Julie; Lanning, Beth

2015-10-01

Equine-assisted learning (EAL) is an experiential modality which utilizes horses to provide a unique learning experience for personal growth. Research by Damon et al. (Appl Dev Sci 7:119-128, 2003) suggests a positive relationship between hope and positive developmental trajectories. Hagen et al. (Am J Orthopsychiatr 75:211-219, 2005) showed hope to be a protective factor associated with adaptive functioning in at-risk youth. Ashby et al. (J Couns Dev 89:131-139, 2011) found a significant inverse relationship between hope and depression: as hope increases, depression decreases. The current study investigates the impact of a non-riding EAL curriculum entitled L.A.S.S.O. (Leading Adolescents to Successful School Outcomes) on levels of hope and depression in at-risk youth. The study uses an experimental design with longitudinal, repeated measures. Participants were randomly assigned to treatment and control groups. Participants in the treatment received 5 weeks of EAL, while participants in the control group received treatment as usual. Repeated measures ANOVA of participants' levels of hope and depression showed statistically significant improvements in the treatment group as compared with the control group. Even a brief (5-week) intervention of EAL had a positive impact on the lives and attitudes of at-risk adolescents, with increased levels of hope and decreased levels of depression.

The Aspergillus fumigatus conidial melanin production is regulated by the bifunctional bHLH DevR and MADS-box RlmA transcription factors.

PubMed

Valiante, Vito; Baldin, Clara; Hortschansky, Peter; Jain, Radhika; Thywißen, Andreas; Straßburger, Maria; Shelest, Ekaterina; Heinekamp, Thorsten; Brakhage, Axel A

2016-10-01

Melanins play a crucial role in defending organisms against external stressors. In several pathogenic fungi, including the human pathogen Aspergillus fumigatus, melanin production was shown to contribute to virulence. A. fumigatus produces two different types of melanins, i.e., pyomelanin and dihydroxynaphthalene (DHN)-melanin. DHN-melanin forms the gray-green pigment characteristic for conidia, playing an important role in immune evasion of conidia and thus for fungal virulence. The DHN-melanin biosynthesis pathway is encoded by six genes organized in a cluster with the polyketide synthase gene pksP as a core element. Here, cross-species promoter analysis identified specific DNA binding sites in the DHN-melanin biosynthesis genes pksP-arp1 intergenic region that can be recognized by bHLH and MADS-box transcriptional regulators. Independent deletion of two genes coding for the transcription factors DevR (bHLH) and RlmA (MADS-box) interfered with sporulation and reduced the expression of the DHN-melanin gene cluster. In vitro and in vivo experiments proved that these transcription factors cooperatively regulate pksP expression acting both as repressors and activators in a mutually exclusive manner. The dual role executed by each regulator depends on specific DNA motifs recognized in the pksP promoter region. © 2016 John Wiley & Sons Ltd.

A NEW DENSITY VARIANCE-MACH NUMBER RELATION FOR SUBSONIC AND SUPERSONIC ISOTHERMAL TURBULENCE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Konstandin, L.; Girichidis, P.; Federrath, C.

The probability density function of the gas density in subsonic and supersonic, isothermal, driven turbulence is analyzed using a systematic set of hydrodynamical grid simulations with resolutions of up to 1024{sup 3} cells. We perform a series of numerical experiments with root-mean-square (rms) Mach number M ranging from the nearly incompressible, subsonic (M=0.1) to the highly compressible, supersonic (M=15) regime. We study the influence of two extreme cases for the driving mechanism by applying a purely solenoidal (divergence-free) and a purely compressive (curl-free) forcing field to drive the turbulence. We find that our measurements fit the linear relation between themore » rms Mach number and the standard deviation (std. dev.) of the density distribution in a wide range of Mach numbers, where the proportionality constant depends on the type of forcing. In addition, we propose a new linear relation between the std. dev. of the density distribution {sigma}{sub {rho}} and that of the velocity in compressible modes, i.e., the compressible component of the rms Mach number, M{sub comp}. In this relation the influence of the forcing is significantly reduced, suggesting a linear relation between {sigma}{sub {rho}} and M{sub comp}, independent of the forcing, and ranging from the subsonic to the supersonic regime.« less

Robert Burk Gives Inaugural Wacholder Lecture on HPV and cervical cancer research

Cancer.gov

In April 2018, DCEG welcomed Robert Burk, M.D., as the inaugural Sholom Wacholder Distinguished Lecturer in Quantitative Health Sciences. The lectureship is named in memory of Dr. Sholom Wacholder, who worked at the intersection of quantitative reasoning and science.

Evaluation Report III: The Robert Noyce Scholarship Program at CSUB

ERIC Educational Resources Information Center

Wang, Jianjun

2013-01-01

California State University, Bakersfield (CSUB) received funding from National Science Foundation's (NSF) Robert Noyce Teacher Scholarship Program to recruit Noyce Scholars from upper-division science, technology, engineering, and mathematics (STEM) majors, graduate students, and professionals switched to STEM teaching from other fields (NSF…

Robert Weinberg: Scientist of the Year.

ERIC Educational Resources Information Center

Langone, John

1983-01-01

Highlights the background, career, and major accomplishments of Robert Allan Weinberg, professor of Biology at the Massachusetts Institute of Technology. His accomplishments and research interests focus on oncogenes, genes capable of causing cancer. The discovery of these genes has revealed the central mechanism of cancer. (Author/JN)

78 FR 62648 - Cat Island National Wildlife Refuge; West Feliciana Parish, Louisiana

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... comments, questions, and requests for information to: Robert Strader, Project Leader, USFWS, Lower... Paduani, Project Planner, 662-323-5548, [email protected] or Robert Strader, Project Leader, 601... conserve, enhance, and restore the historic native bottomland community characteristics of the lower...

The Legacy of Robert M. Gagne.

ERIC Educational Resources Information Center

Richey, Rita C., Ed.

This book highlights and discusses the contributions of Robert M. Gagne to the field of instructional technology. Section One presents the core concepts of Gagne's theory and contains reprints of the following five journal articles by Gagne: "Contributions of Learning to Human Development,""Learning Hierarchies,""Domains…

Official portrait of astronaut Robert D.Cabana

NASA Technical Reports Server (NTRS)

1985-01-01

Official portrait of astronaut Robert D.Cabana, a colonel in the United States Marine Corps (USMC) and a member of the 1985 Astronaut Class 11. Cabana is wearing a blue flight suit and poses with an American flag and asmall model of the space shuttle orbiter.

Robert Owen, William Maclure and New Harmony.

ERIC Educational Resources Information Center

Mclaren, David J.

1996-01-01

Discusses the utopian philosophy and related educational practices of the early 19th-century communitarian settlement in New Harmony, Indiana. The settlement failed after several years, due in no small part to the falling out between its two main supporters, Robert Owen and William Maclure. (MJP)

Robert Seymour Bridges om: Poet, physician and philosopher

PubMed Central

James, Theodore

1994-01-01

There has not been an English poet more interested in prosody nor physician more taken to medicine for its human contact, nor philosopher who lived closer to the tenets of his belief, than Robert Bridges (1844–1930). ImagesFigure 1.Figure 2. PMID:8207726

Rule of Law in Afghanistan -- Time for a New Approach?

DTIC Science & Technology

2009-03-17

accessed November 7 2008) 139 Gates, Robert M. Afghanistan Command Restructuring Worthy of Consideration. Texarkana , Texas, May 2, 2008 By Donna Miles...products/GAO-08-661 (accessed November 2 2008) Gates, Robert M. Afghanistan Command Restructuring Worthy of Consideration. Texarkana , Texas, May

1100398

NASA Image and Video Library

2011-03-24

CHARLES BOLDEN NASA ADMINISTRATOR TOURING AND SPEAKING AT THE US. SPACE AND ROCKET CENTER, HUNTSVILLE, ALABAMA. ACCOMPANYING ADMINISTRATOR BOLDEN ARE DR. DEBORAH BARNHART, CEO OF THE USSARC, ROBERT LIGHTFOOT, CENTER DIRECTOR OF MARSHALL SPACE FLIGHT CENTER AND RETIRED NASA ASTRONAUT ROBERT LEE “HOOT” GIBSON, ADMINISTRATOR BOLDEN’S FIRST SPACE FLIGHT COMMANDER.

78 FR 36557 - Iowa; Major Disaster and Related Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-18

... President issued a major disaster declaration under the authority of the Robert T. Stafford Disaster Relief... warrant a major disaster declaration under the Robert T. Stafford Disaster Relief and Emergency Assistance....046, Fire Management Assistance Grant; 97.048, Disaster Housing Assistance to Individuals and...

76 FR 44031 - Arkansas; Major Disaster and Related Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-22

... President issued a major disaster declaration under the authority of the Robert T. Stafford Disaster Relief... a major disaster declaration under the Robert T. Stafford Disaster Relief and Emergency Assistance....046, Fire Management Assistance Grant; 97.048, Disaster Housing Assistance to Individuals and...