Design of multihundredwatt DIPS for robotic space missions

NASA Technical Reports Server (NTRS)

Bents, D. J.; Geng, S. M.; Schreiber, J. G.; Withrow, C. A.; Schmitz, P. C.; Mccomas, Thomas J.

1991-01-01

Design of a dynamic isotope power system (DIPS) general purpose heat source (GPHS) and small free piston Stirling engine (FPSE) is being pursued as a potential lower cost alternative to radioisotope thermoelectric generators (RTG's). The design is targeted at the power needs of future unmanned deep space and planetary surface exploration missions ranging from scientific probes to SEI precursor missions. These are multihundredwatt missions. The incentive for any dynamic system is that it can save fuel which reduces cost and radiological hazard. However, unlike a conventional DIPS based on turbomachinery converions, the small Stirling DIPS can be advantageously scaled to multihundred watt unit size while preserving size and weight competitiveness with RTG's. Stirling conversion extends the range where dynamic systems are competitive to hundreds of watts (a power range not previously considered for dynamic systems). The challenge of course is to demonstrate reliability similar to RTG experience. Since the competative potential of FPSE as an isotope converter was first identified, work has focused on the feasibility of directly integrating GPHS with the Stirling heater head. Extensive thermal modeling of various radiatively coupled heat source/heater head geometries were performed using data furnished by the developers of FPSE and GPHS. The analysis indicates that, for the 1050 K heater head configurations considered, GPHS fuel clad temperatures remain within safe operating limits under all conditions including shutdown of one engine. Based on these results, preliminary characterizations of multihundred watt units were established.

Design of small Stirling dynamic isotope power system for robotic space missions

NASA Technical Reports Server (NTRS)

Bents, D. J.; Schreiber, J. G.; Withrow, C. A.; Mckissock, B. I.; Schmitz, P. C.

1992-01-01

Design of a multihundred-watt Dynamic Isotope Power System (DIPS) based on the U.S. Department of Energy (DOE) General Purpose Heat Source (GPHS) and small (multihundred-watt) free-piston Stirling engine (FPSE) technology is being pursued as a potential lower cost alternative to radioisotope thermoelectric generators (RTG's). The design is targeted at the power needs of future unmanned deep space and planetary surface exploration missions ranging from scientific probes to Space Exploration Initiative precursor missions. Power level for these missions is less than a kilowatt. Unlike previous DIPS designs which were based on turbomachinery conversion (e.g. Brayton), this small Stirling DIPS can be advantageously scaled down to multihundred-watt unit size while preserving size and mass competitiveness with RTG's. Preliminary characterization of units in the output power ranges 200-600 We indicate that on an electrical watt basis the GPHS/small Stirling DIPS will be roughly equivalent to an advanced RTG in size and mass but require less than a third of the isotope inventory.

TAGS 85/2N RTG Power for Viking Lander Capsule

DOE R&D Accomplishments Database

1969-08-01

Results of studies performed by Isotopes, Inc., Nuclear Systems Division, to optimize and baseline a TAGS 85/2N RTG for the Viking Lander Capsule prime electrical power source are presented. These studies generally encompassed identifying the Viking RTG mission profile and design requirements, and establishing a baseline RTG design consistent with these requirements.

Small Stirling dynamic isotope power system for robotic space missions

NASA Technical Reports Server (NTRS)

Bents, D. J.

1992-01-01

The design of a multihundred-watt Dynamic Isotope Power System (DIPS), based on the U.S. Department of Energy (DOE) General Purpose Heat Source (GPHS) and small (multihundred-watt) free-piston Stirling engine (FPSE), is being pursued as a potential lower cost alternative to radioisotope thermoelectric generators (RTG's). The design is targeted at the power needs of future unmanned deep space and planetary surface exploration missions ranging from scientific probes to Space Exploration Initiative precursor missions. Power level for these missions is less than a kilowatt. The incentive for any dynamic system is that it can save fuel and reduce costs and radiological hazard. Unlike DIPS based on turbomachinery conversion (e.g. Brayton), this small Stirling DIPS can be advantageously scaled to multihundred-watt unit size while preserving size and mass competitiveness with RTG's. Stirling conversion extends the competitive range for dynamic systems down to a few hundred watts--a power level not previously considered for dynamic systems. The challenge for Stirling conversion will be to demonstrate reliability and life similar to RTG experience. Since the competitive potential of FPSE as an isotope converter was first identified, work has focused on feasibility of directly integrating GPHS with the Stirling heater head. Thermal modeling of various radiatively coupled heat source/heater head geometries has been performed using data furnished by the developers of FPSE and GPHS. The analysis indicates that, for the 1050 K heater head configurations considered, GPHS fuel clad temperatures remain within acceptable operating limits. Based on these results, preliminary characterizations of multihundred-watt units have been established.

Stirling Radioisotope Power System as an Alternative for NASAs Deep Space Missions

NASA Astrophysics Data System (ADS)

Shaltens, R. K.; Mason, L. S.; Schreiber, J. G.

2001-01-01

The NASA Glenn Research Center (GRC) and the Department of Energy (DOE) are developing a free-piston Stirling convertor for a Stirling Radioisotope Power System (SRPS) to provide on-board electric power for future NASA deep space missions. The SRPS currently being developed provides about 100 watts and reduces the amount of radioisotope fuel by a factor of four over conventional Radioisotope Thermoelectric Generators (RTG). The present SRPS design has a specific power of approximately 4 W/kg which is comparable to an RTG. GRC estimates for advanced versions of the SRPS with improved heat source integration, lightweight Stirling convertors, composite radiators, and chip-packaged controllers improves the specific mass to about 8 W/kg. Additional information is contained in the original extended abstract.

A power conditioning system for radioisotope thermoelectric generator energy sources

NASA Technical Reports Server (NTRS)

Gillis, J. A., Jr.

1974-01-01

The use of radioisotope thermoelectric generators (RTG) as the primary source of energy in unmanned spacecraft is discussed. RTG output control, power conditioning system requirements, the electrical design, and circuit performance are also discussed.

A Survey of Current Russion RTG Capabilities

NASA Technical Reports Server (NTRS)

Chmielewski, A.; Borshchevsky, A.; Lange, R.; Cook, B.

1994-01-01

Supplying radioisotope thermoelectric generators (RTG) to American space missions became very complex. The process is marred by many obstacles: high cost, lack of new developments, difficult launch approval and NEPA compliance. At the same time there are many ambitious space missions for which an RTG would indisputably be the lightest, smallest and most robust power source. An American delegation investigated status of RTG production in Russia to decide if our product line could be supplemented by the Russian designs.

Final safety analysis report for the Galileo Mission: Volume 2: Summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The General Purpose Heat Source Radioisotope Thermoelectric Generator (GPHS-RTG) will be used as the prime source of electric power for the spacecraft on the Galileo mission. The use of radioactive material in these missions necessitates evaluations of the radiological risks that may be encountered by launch complex personnel and by the Earth's general population resulting from postulated malfunctions or failures occurring in the mission operations. The purpose of the Final Safety Analysis Report (FSAR) is to present the analyses and results of the latest evaluation of the nuclear safety potential of the GPHS-RTG as employed in the Galileo mission. Thismore » evaluation is an extension of earlier work that addressed the planned 1986 launch using the Space Shuttle Vehicle with the Centaur as the upper stage. This extended evaluation represents the launch by the Space Shuttle/IUS vehicle. The IUS stage has been selected as the vehicle to be used to boost the Galileo spacecraft into the Earth escape trajectory after the parking orbit is attained.« less

RTGs on Transit

NASA Astrophysics Data System (ADS)

Dassoulas, John; McNutt, Ralph L.

2007-01-01

Transit, the US Navy's Navigation Satellite System was conceived at the Applied Physics Laboratory in 1957 by observing the Doppler shift while tracking Sputnik I. As spacecraft development proceeded there was concern about the ability of batteries to maintain the hermetic seal over a 5-year operational life requirement; therefore, alternate energy sources were investigated. The radioisotope thermoelectric generator (RTG) concept was pursued and resulted in the launch of SNAP 3s, providing partial power on both Transit 4A and 4B. SNAP 9s provided full power on three Transit 5BNs. All launches occurred in the early 1960s. When the U.S. conducted the high altitude nuclear test from Johnson Island, several spacecraft were lost due to artificial enhancement of charged particles in the Earth's magnetosphere resulting in rapid degradation of solar cell power production. This led to the decision to have both an RTG and Solar cell/battery design for Transit power systems; hence, a new RTG design, with a separable heat source and radiative coupling to the thermoelectric elements, was flown on TRIAD. This pioneering effort provided the impetus for future RTGs on interplanetary spacecraft. This paper describes the origin and purpose of the Transit program and provides details on the five satellites in that program that were powered by the first American RTGs used in space. The rationale and some of the challenges inherent in that use are also described.

Characterization of Pu-238 heat source granule containment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richardson Ii, P D; Thronas, D L; Romero, J P

2008-01-01

The Milliwatt Radioisotopic Thermoelectric Generator (RTG) provides power for permissive-action links. These nuclear batteries convert thermal energy to electrical energy using a doped silicon-germanium thermopile. The thermal energy is provided by a heat source made of {sup 238}Pu, in the form of {sup 238}PuO{sub 2} granules. The granules are contained in 3 layers of encapsulation. A thin T-111 liner surrounds the {sup 238}PuO{sub 2} granules and protects the second layer (strength member) from exposure to the fuel granules. The T-111 strength member contains the fuel under impact condition. An outer clad of Hastelloy-C protects the T-111 from oxygen embrittlement. Themore » T-111 strength member is considered the critical component in this {sup 238}PuO{sub 2} containment system. Any compromise in the strength member is something that needs to be characterized. Consequently, the T-111 strength member is characterized upon it's decommissioning through Scanning Electron Microscopy (SEM), and Metallography. SEM is used in Secondary Electron mode to reveal possible grain boundary deformation and/or cracking in the region of the strength member weld. Deformation and cracking uncovered by SEM are further characterized by Metallography. Metallography sections are mounted and polished, observed using optical microscopy, then documented in the form of photomicrographs. SEM may further be used to examine polished Metallography mounts to characterize elements using the SEM mode of Energy Dispersive X-ray Spectroscopy (EDS). This paper describes the characterization of the metallurgical condition of decommissioned RTG heat sources.« less

So What's an RTG and Are They Safe?

NASA Technical Reports Server (NTRS)

Barret, Chris; Hughes, R. W. (Technical Monitor)

2001-01-01

When one considers space missions to the outer edges of our solar system and far beyond, our sun cannot be relied on to produce the required spacecraft (s/c) power. Solar energy diminishes as the square of the distance from the Sun. At Mars it is only 43% of that at earth. At Jupiter, it falls off to only 3.6% of Earth's. By the time we get out to Pluto, solar energy is only .066% what it is on Earth. Beyond the orbit of Mars, it is not practical to depend on solar power for a s/c. However, the farther out we go the more power we need to heat the s/c and to transmit data back to Earth over the long distances. On Earth, knowledge is power. In the outer solar system, power is knowledge. Solar arrays only operate at 19% efficiency, are very vulnerable to damage from radiation and temperature extremes, and cannot be used for even nearby missions that operate in extended darkness, or under the surface of a planet or moon. Twenty-six U.S. space missions, from the Transit to Cassini, have used radioisotope power systems and heater units to take s/c to the far reaches of our solar system and have demonstrated an outstanding record of safety and reliability. Radioisotope thermoelectric generators (RTG's) have proven to be safe, reliable, maintenance-free, and capable of providing both thermal and electrical power for decades under the harsh environments of deep space. RTG's have no problem operating in the high radiation belts of space, the extreme temperatures, or the severe dust storms of Mars, and they have proven to be the most reliable power source ever flown on U.S. s/c. For example, the two Pioneer s/c operated for more than two decades and the Voyager s/c may last for 40 years. RTG's are not nuclear reactors, they serve only as power generators and are not involved in the propulsion of the s/c. They operate on the principle of thermoelectric generation that converts heat directly into electricity, they have no moving parts, are extremely reliable, and have met or exceeded all safety and performance expectations. Federal laws and regulations require analysis and evaluation of the safety risks and any potential environmental impacts. Extensive safety testing of RTG's and RTG components has been performed by the U.S. Department of Energy (DOE) to demonstrate the ability to survive accidents related to Space Shuttle launches and assure that the systems would be safe under all accident conditions, including accidents at or near the launch pad or during orbital reentry. Many design improvements have been made over the four decades that RTG's have been flown on space missions. This paper outlines the operation and safety standards of RTG's and the advanced developments expected to be used on future deep space missions such as the Europa Orbiter, Pluto/Kuiper Express, Solar Probe, Europa Lander, and Titan Explorer missions.

Modular Isotopic Thermoelectric Generator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schock, Alfred

1981-01-01

Advanced RTG concepts utilizing improved thermoelectric materials and converter concepts are under study at Fairchild for DOE. The design described here is based on DOE's newly developed radioisotope heat source, and on an improved silicon-germanium material and multicouple converter module under development at Syncal. Fairchild's assignment was to combine the above into an attractive power system for use in space, and to assess the specific power and other attributes of that design.

Development of a Multi-bus, Multi-source Reconfigurable Stirling Radioisotope Power System Test Bed

NASA Technical Reports Server (NTRS)

Coleman, Anthony S.

2004-01-01

The National Aeronautics and Space Administration (NASA) has typically used Radioisotope Thermoelectric Generators (RTG) as their source of electric power for deep space missions. A more efficient and potentially more cost effective alternative to the RTG, the high efficiency 110 watt Stirling Radioisotope Generator 110 (SRG110) is being developed by the Department of Energy (DOE), Lockheed Martin (LM), Stirling Technology Company (STC) and NASA Glenn Research Center (GRC). The SRG110 consists of two Stirling convertors (Stirling Engine and Linear Alternator) in a dual-opposed configuration, and two General Purpose Heat Source (GPHS) modules. Although Stirling convertors have been successfully operated as a power source for the utility grid and as a stand-alone portable generator, demonstration of the technology required to interconnect two Stirling convertors for a spacecraft power system has not been attempted. NASA GRC is developing a Power System Test Bed (PSTB) to evaluate the performance of a Stirling convertor in an integrated electrical power system application. This paper will describe the status of the PSTB and on-going activities pertaining to the PSTB in the NASA Thermal-Energy Conversion Branch of the Power and On-Board Propulsion Technology Division.

A Deep Space Power System Option Based on Synergistic Power Conversion Technologies

NASA Technical Reports Server (NTRS)

Schreiber, Jeffrey G.

2000-01-01

Deep space science missions have typically used radioisotope thermoelectric generator (RTG) power systems. The RTG power system has proven itself to be a rugged and highly reliable power system over many missions, however the thermal-to-electric conversion technology used was approximately 5% efficient. While the relatively low efficiency has some benefits in terms of system integration, there are compelling reasons why a more efficient conversion system should be pursued. The cost savings alone that are available as a result of the reduced isotope inventory are significant. The Advanced Radioisotope Power System (ARPS) project was established to fulfill this goal. Although it was not part of the ARPS project, Stirling conversion technology is being demonstrated with a low level of funding by both NASA and DOE. A power system with Stirling convertors. although intended for use with an isotope heat source. can be combined with other advanced technologies to provide a novel power system for deep space missions. An inflatable primary concentrator would be used in combination with a refractive secondary concentrator (RSC) as the heat source to power the system. The inflatable technology as a structure has made great progress for a variety of potential applications such as communications reflectors, radiators and solar arrays. The RSC has been pursued for use in solar thermal propulsion applications, and it's unique properties allow some advantageous system trades to be made. The power system proposed would completely eliminate the isotope heat source and could potentially provide power for science missions to planets as distant as Uranus. This paper will present the background and developmental status of the technologies and will then describe the power system being proposed.

Characterization of Pu-238 Heat Source Granule Containment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richardson, Paul Dean II; Sanchez, Joey Leo; Wall, Angelique Dinorah

The Milliwatt Radioisotopic Themoelectric Generator (RTG) provides power for permissive-action links. Essentially these are nuclear batteries that convert thermal energy to electrical energy using a doped silicon-germanium thermopile. The thermal energy is provided by a heat source made of 238Pu, in the form of 238PuO 2 granules. The granules are contained by 3 layers of encapsulation. A thin T-111 liner surrounds the 238PuO 2 granules and protects the second layer (strength member) from exposure to the fuel granules. An outer layer of Hastalloy-C protects the T-111 from oxygen embrittlement. The T-111 strength member is considered the critical component in thismore » 238PuO 2 containment system. Any compromise in the strength member seen during destructive testing required by the RTG surveillance program is characterized. The T-111 strength member is characterized through Scanning Electron Microscopy (SEM), and Metallography. SEM is used in the Secondary Electron mode to reveal possible grain boundary deformation and/or cracking in the region of the strength member weld. Deformation and cracking uncovered by SEM are further characterized by Metallography. Metallography sections are mounted and polished, observed using optical microscopy, then documented in the form of microphotographs. SEM mat further be used to examine polished Metallography mounts to characterize elements using the SEM mode of Energy Dispersive X-ray spectroscopy (EDS).« less

The long-term performance degradation of a radioisotope thermoelectric generator using silicon germanium

NASA Technical Reports Server (NTRS)

Stapfer, G.; Truscello, V. C.

1976-01-01

The successful utilization of a radioisotope thermoelectric generator (RTG) as the power source for spaceflight missions requires that the performance of such an RTG be predictable throughout the mission. Several mechanisms occur within the generator which tend to degrade the performance as a function of operating time. The impact which these mechanisms have on the available output power of an RTG depends primarily on such factors as time, temperature and self-limiting effects. The relative magnitudes, rates and temperature dependency of these various degradation mechanisms have been investigated separately by coupon experiments as well as 4-couple and 18-couple module experiments. This paper discusses the different individual mechanisms and summarizes their combined influence on the performance of an RTG. Also presented as part of the RTG long-term performance characteristics is the sensitivity of the available RTG output power to variations of the individual degradation mechanisms thus identifying the areas of greatest concern for a successful long-term mission.

Evaluation of Aqueous and Powder Processing Techniques for Production of Pu-238-Fueled General Purpose Heat Sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2008-06-01

This report evaluates alternative processes that could be used to produce Pu-238 fueled General Purpose Heat Sources (GPHS) for radioisotope thermoelectric generators (RTG). Fabricating GPHSs with the current process has remained essentially unchanged since its development in the 1970s. Meanwhile, 30 years of technological advancements have been made in the fields of chemistry, manufacturing, ceramics, and control systems. At the Department of Energy’s request, alternate manufacturing methods were compared to current methods to determine if alternative fabrication processes could reduce the hazards, especially the production of respirable fines, while producing an equivalent GPHS product. An expert committee performed the evaluationmore » with input from four national laboratories experienced in Pu-238 handling.« less

Improved techniques for predicting spacecraft power

NASA Technical Reports Server (NTRS)

Chmielewski, A. B.

1987-01-01

Radioisotope Thermoelectric Generators (RTGs) are going to supply power for the NASA Galileo and Ulysses spacecraft now scheduled to be launched in 1989 and 1990. The duration of the Galileo mission is expected to be over 8 years. This brings the total RTG lifetime to 13 years. In 13 years, the RTG power drops more than 20 percent leaving a very small power margin over what is consumed by the spacecraft. Thus it is very important to accurately predict the RTG performance and be able to assess the magnitude of errors involved. The paper lists all the error sources involved in the RTG power predictions and describes a statistical method for calculating the tolerance.

An evaluation of some special techniques for nuclear waste disposal in space

NASA Technical Reports Server (NTRS)

Mackay, J. S.

1973-01-01

A preliminary examination is reported of several special ways for space disposal of nuclear waste material which utilize the radioactive heat in the waste to assist in the propulsion for deep space trajectories. These include use of the wastes in a thermoelectric generator (RTG) which operates an electric propulsion device and a radioisotope - thermal thruster which uses hydrogen or ammonia as the propellant. These propulsive devices are compared to the space tug and the space tug/solar electric propulsion combination for disposal of waste on a solar system escape trajectory. Such comparisons indicate that the waste-RTG approach has considerable potential provided the combined specific mass of the waste container - RTG system does not exceed approximately 150 kg/kw sub e. Several exploratory numerical calculations have been made for high earth orbit and Earth escape destinations.

U.S. Space Radioisotope Power Systems and Applications: Past, Present and Future

NASA Technical Reports Server (NTRS)

Cataldo, Robert L.; Bennett, Gary L.

2011-01-01

Radioisotope power systems (RPS) have been essential to the U.S. exploration of outer space. RPS have two primary uses: electrical power and thermal power. To provide electrical power, the RPS uses the heat produced by the natural decay of a radioisotope (e.g., plutonium-238 in U.S. RPS) to drive a converter (e.g., thermoelectric elements or Stirling linear alternator). As a thermal power source the heat is conducted to whatever component on the spacecraft needs to be kept warm; this heat can be produced by a radioisotope heater unit (RHU) or by using the excess heat of a radioisotope thermoelectric generator (RTG). As of 2010, the U.S. has launched 41 RTGs on 26 space systems. These space systems have ranged from navigational satellites to challenging outer planet missions such as Pioneer 10/11, Voyager 1/2, Galileo, Ulysses, Cassini and the New Horizons mission to Pluto. In the fall of 2011, NASA plans to launch the Mars Science Laboratory (MSL) that will employ the new Multi-Mission Radioisotope Thermoelectric Generator (MMRTG) as the principal power source. Hundreds of radioisotope heater units (RHUs) have been launched to provide warmth to Apollo 11, used to provide heating of critical components in a seismic experiment package, Pioneer 10/11, Voyager 1/2, Galileo, Cassini, Mars Pathfinder, MER rovers, etc. to provide temperature control to critical spacecraft electronics and other mechanical devices such as propulsion system propellant valves. A radioisotope (electrical) power source or system (RPS) consists of three basic elements: (1) the radioisotope heat source that provides the thermal power, (2) the converter that transforms the thermal power into electrical power and (3) the heat rejection radiator. Figure 1 illustrates the basic features of an RPS. The idea of a radioisotope power source follows closely after the early investigations of radioactivity by researchers such as Henri Becquerel (1852-1908), Marie Curie (1867-1935), Pierre Curie (1859-1906) and R. J. Strut. Almost 100 years ago, in 1913, English physicist H. G. J. Moseley (1887-1915) constructed the first nuclear battery using a vacuum flask and 20 mCi of radium (Corliss and Harvey, 1964, Proceedings of the Royal Society, 1913). After World War II, serious interest in radioisotope power systems in the U.S. was sparked by studies of space satellites such as North American Aviation s 1947 report on nuclear space power and the RAND Corporation s 1949 report on radioisotope power. (Greenfield, 1947, Gendler and Kock, 1949). Radioisotopes were also considered in early studies of nuclear-powered aircraft (Corliss and Harvey, 1964). In 1951, the U.S. Atomic Energy Commission (AEC) signed several contracts to study a 1-kWe space power plant using reactors or radioisotopes. Several of these studies, which were completed in 1952, recommended the use of RPS. (Corliss and Harvey, 1964). In 1954, the RAND Corporation issued the summary report of the Project Feedback military satellite study in which radioisotope power was considered (Lipp and Salter, 1954, RAND). Paralleling these studies, in 1954, K. C. Jordan and J. H. Birden of the AEC s Mound Laboratory conceived and built the first RTG using chromel-constantan thermocouples and a polonium-210 (210Po or Po-210) radioisotope heat source (see Figure 2). While the power produced (1.8 mWe) was low by today s standards, this first RTG showed the feasibility of RPS. A second thermal battery was built with more Po-210, producing 9.4 mWe. Jordan and Birden concluded that the Po-210 thermal battery would have about ten times the energy of ordinary dry cells of the same mass (Jordan and Birden, 1954). The heat source consisted of a 1-cm-diameter sphere of 57 Ci (1.8 Wt) of Po-210 inside a capsule of nickel-coated cold-rolled steel all inside a container of Lucite. The thermocouples were silver-soldered chromel-constantan. The thermal battery produced 1.8 mWe.

The program at JPL to investigate the nuclear interaction of RTG's with scientific instruments on deep space probes

NASA Technical Reports Server (NTRS)

Truscello, V.

1972-01-01

A major concern in the integration of a radioisotope thermoelectric generator (RTG) with a spacecraft designed to explore the outer planets is the effect of the emitted radiation on the normal operation of scientific instruments. The necessary techniques and tools developed to allow accurate calculation of the neutron and gamma spectrum emanating from the RTG. The specific sources of radiation were identified and quantified. Monte Carlo techniques are then employed to perform the nuclear transport calculations. The results of these studies are presented. An extensive experimental program was initiated to measure the response of a number of scientific components to the nuclear radiation.

Computational modeling of Radioisotope Thermoelectric Generators (RTG) for interplanetary and deep space travel

NASA Astrophysics Data System (ADS)

Nejat, Cyrus; Nejat, Narsis; Nejat, Najmeh

2014-06-01

This research project is part of Narsis Nejat Master of Science thesis project that it is done at Shiraz University. The goals of this research are to make a computer model to evaluate the thermal power, electrical power, amount of emitted/absorbed dose, and amount of emitted/absorbed dose rate for static Radioisotope Thermoelectric Generators (RTG)s that is include a comprehensive study of the types of RTG systems and in particular RTG’s fuel resulting from both natural and artificial isotopes, calculation of the permissible dose radioisotope selected from the above, and conceptual design modeling and comparison between several NASA made RTGs with the project computer model pointing out the strong and weakness points for using this model in nuclear industries for simulation. The heat is being converted to electricity by two major methods in RTGs: static conversion and dynamic conversion. The model that is created for this project is for RTGs that heat is being converted to electricity statically. The model approximates good results as being compared with SNAP-3, SNAP-19, MHW, and GPHS RTGs in terms of electrical power, efficiency, specific power, and types of the mission and amount of fuel mass that is required to accomplish the mission.

Impact of High Resolution SST Data on Regional Weather Forecasts

NASA Technical Reports Server (NTRS)

Jedlovec, Gary J.; Case, Jonathon; LaFontaine, Frank; Vazquez, Jorge; Mattocks, Craig

2010-01-01

Past studies have shown that the use of coarse resolution SST products such as from the real-time global (RTG) SST analysis[1] or other coarse resolution once-a-day products do not properly portray the diurnal variability of fluxes of heat and moisture from the ocean that drive the formation of low level clouds and precipitation over the ocean. For example, the use of high resolution MODIS SST composite [2] to initialize the Advanced Research Weather Research and Forecast (WRF) (ARW) [3] has been shown to improve the prediction of sensible weather parameters in coastal regions [4][5}. In an extend study, [6] compared the MODIS SST composite product to the RTG SST analysis and evaluated forecast differences for a 6 month period from March through August 2007 over the Florida coastal regions. In a comparison to buoy data, they found that that the MODIS SST composites reduced the bias and standard deviation over that of the RTG data. These improvements led to significant changes in the initial and forecasted heat fluxes and the resulting surface temperature fields, wind patterns, and cloud distributions. They also showed that the MODIS composite SST product, produced for the Terra and Aqua satellite overpass times, captured a component of the diurnal cycle in SSTs not represented in the RTG or other one-a-day SST analyses. Failure to properly incorporate these effects in the WRF initialization cycle led to temperature biases in the resulting short term forecasts. The forecast impact was limited in some situations however, due to composite product inaccuracies brought about by data latency during periods of long-term cloud cover. This paper focuses on the forecast impact of an enhanced MODIS/AMSR-E composite SST product designed to reduce inaccuracies due data latency in the MODIS only composite product.

GPHS-RTG performance on the Galileo mission

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hemler, R.J.; Cockfield, R.D.

The Galileo spacecraft, launched in October, 1989, is powered by two General Purpose Heat source-Radioisotope Thermoelectric Generator (GPHS-RTGs). These RTGs were designed, built, and tested by General Electric under contract from the Office of Special Applications of the Department of Energy (DOE). Isotope heat source installation and additional testing of these RTGs were performed at DOE's EG G Mound Facility in Miamisburg, Ohio. This paper provides a report on performance of the RTGs during launch and the early phases of the eight year Galileo mission.The effect of long term storage of the RTGs on power output, since the originally scheduledmore » launch data in May, 1986, will be dicussed, including the effects of helium buildup and subsequent purging with xenon. The RTGs performed as expected during the launch transient, met all specified power requirements for Beginning of Mission (BOM), and continue to follow prediced performance characteristics during the first year of the Galileo mission.« less

Small Stirling dynamic isotope power system for multihundred-watt robotic missions

NASA Technical Reports Server (NTRS)

Bents, David J.

1991-01-01

Free Piston Stirling Engine (FPSE) and linear alternator (LA) technology is combined with radioisotope heat sources to produce a compact dynamic isotope power system (DIPS) suitable for multihundred watt space application which appears competitive with advance radioisotope thermoelectric generators (RTGs). The small Stirling DIPS is scalable to multihundred watt power levels or lower. The FPSE/LA is a high efficiency convertor in sizes ranging from tens of kilowatts down to only a few watts. At multihundred watt unit size, the FPSE can be directly integrated with the General Purpose Heat Source (GPHS) via radiative coupling; the resulting dynamic isotope power system has a size and weight that compares favorably with the advanced modular (Mod) RTG, but requires less than a third the amount of isotope fuel. Thus the FPSE extends the high efficiency advantage of dynamic systems into a power range never previously considered competitive for DIPS. This results in lower fuel cost and reduced radiological hazard per delivered electrical watt.

Small Stirling dynamic isotope power system for multihundred-watt robotic missions

NASA Technical Reports Server (NTRS)

Bents, David J.

1991-01-01

Free piston Stirling Engine (FPSE) and linear alternator (LA) technology is combined with radioisotope heat sources to produce a compact dynamic isotope power system (DIPS) suitable for multihundred watt space application which appears competitive with advanced radioisotope thermoelectric generators (RTGs). The small Stirling DIPS is scalable to multihundred watt power levels or lower. The FPSE/LA is a high efficiency convertor in sizes ranging from tens of kilowatts down to only a few watts. At multihundred watt unit size, the FPSE can be directly integrated with the General Purpose Heat Source (GPHS) via radiative coupling; the resulting dynamic isotope power system has a size and weight that compares favorably with the advanced modular (Mod) RTG, but requires less than a third the amount of isotope fuel. Thus the FPSE extends the high efficiency advantage of dynamic systems into a power range never previously considered competitive for DIPS. This results in lower fuel cost and reduced radiological hazard per delivered electrical watt.

Technology-based design and scaling for RTGs for space exploration in the 100 W range

NASA Astrophysics Data System (ADS)

Summerer, Leopold; Pierre Roux, Jean; Pustovalov, Alexey; Gusev, Viacheslav; Rybkin, Nikolai

2011-04-01

This paper presents the results of a study on design considerations for a 100 W radioisotope thermo-electric generator (RTG). Special emphasis has been put on designing a modular, multi-purpose system with high overall TRL levels and making full use of the extensive Russian heritage in the design of radioisotope power systems. The modular approach allowed insight into the scaling of such RTGs covering the electric power range from 50 to 200 W e (EoL). The retained concept is based on a modular thermal block structure, a radiative inner-RTG heat transfer and using a two-stage thermo-electric conversion system.

Pump for delivering heated fluids

NASA Technical Reports Server (NTRS)

Sabelman, E. E. (Inventor)

1973-01-01

A thermomechanical pump particularly suited for use in pumping a warming fluid obtained from an RTG (Radioisotope Thermal Generator) through science and flight instrumentation aboard operative spacecraft is described. The invention is characterized by a pair of operatively related cylinders, each including a reciprocating piston head dividing the cylinder into a pressure chamber confining therein a vaporizable fluid, and a pumping chamber for propelling the warming fluid, and a fluid delivery circuit for alternately delivering the warming fluid from the RTG through the pressure chamber of one cylinder to the pumping chamber of the other cylinder, whereby the vaporizable fluid within the pair of pressure chambers alternately is vaporized and condensed for driving the associated pistons in pumping and intake strokes.

Sfp1 and Rtg3 reciprocally modulate carbon source‐conditional stress adaptation in the pathogenic yeast Candida albicans

PubMed Central

Kastora, Stavroula L.; Herrero‐de‐Dios, Carmen; Avelar, Gabriela M.; Munro, Carol A.

2017-01-01

Summary The pathogenicity of the clinically important yeast, Candida albicans, is dependent on robust responses to host‐imposed stresses. These stress responses have generally been dissected in vitro at 30°C on artificial growth media that do not mimic host niches. Yet host inputs, such as changes in carbon source or temperature, are known to affect C. albicans stress adaptation. Therefore, we performed screens to identify novel regulators that promote stress resistance during growth on a physiologically relevant carboxylic acid and at elevated temperatures. These screens revealed that, under these ‘non‐standard’ growth conditions, numerous uncharacterised regulators are required for stress resistance in addition to the classical Hog1, Cap1 and Cta4 stress pathways. In particular, two transcription factors (Sfp1 and Rtg3) promote stress resistance in a reciprocal, carbon source‐conditional manner. SFP1 is induced in stressed glucose‐grown cells, whereas RTG3 is upregulated in stressed lactate‐grown cells. Rtg3 and Sfp1 regulate the expression of key stress genes such as CTA4, CAP1 and HOG1 in a carbon source‐dependent manner. These mechanisms underlie the stress sensitivity of C. albicans sfp1 cells during growth on glucose, and rtg3 cells on lactate. The data suggest that C. albicans exploits environmentally contingent regulatory mechanisms to retain stress resistance during host colonisation. PMID:28574606

General-Purpose Heat Source Safety Verification Test Program: Edge-on flyer plate tests

NASA Astrophysics Data System (ADS)

George, T. G.

1987-03-01

The radioisotope thermoelectric generator (RTG) that will supply power for the Galileo and Ulysses space missions contains 18 General-Purpose Heat Source (GPHS) modules. The GPHS modules provide power by transmitting the heat of Pu-238 alpha-decay to an array of thermoelectric elements. Each module contains four Pu-238O2-fueled clads and generates 250 W(t). Because the possibility of a launch vehicle explosion always exists, and because such an explosion could generate a field of high-energy fragments, the fueled clads within each GPHS module must survive fragment impact. The edge-on flyer plate tests were included in the Safety Verification Test series to provide information on the module/clad response to the impact of high-energy plate fragments. The test results indicate that the edge-on impact of a 3.2-mm-thick, aluminum-alloy (2219-T87) plate traveling at 915 m/s causes the complete release of fuel from capsules contained within a bare GPHS module, and that the threshold velocity sufficient to cause the breach of a bare, simulant-fueled clad impacted by a 3.5-mm-thick, aluminum-alloy (5052-TO) plate is approximately 140 m/s.

238PuO 2 Fuel and Dosimetry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mayo, Douglas R.; Rawool-Sullivan, Mohini; Garner, Scott Edward

2016-06-01

238Pu is an ideal material for use as a heat source with its half-life of 87.7 years and copious particle emissions. 238Pu radioisotope thermoelectric generators (RTGs) have found use for pacemakers, Apollo Space missions, Mars rovers, and Voyager spacecraft. In evaluating the dose to personnel and components near a 238Pu-based RTG, a number of additional nuclides and their daughter products must be considered to get an accurate estimate for γ-dose, and the amount of 17O and 18O for the neutron-dose must be considered. This paper looks at the contributing nuclides and their daughter products that add the most to themore » dose rates.« less

Radioisotope thermal photovoltaic application of the GaSb solar cell

NASA Technical Reports Server (NTRS)

Morgan, M. D.; Horne, W. E.; Day, A. C.

1991-01-01

An examination of a RTVP (radioisotopic thermophotovoltaic) conceptual design has shown a high potential for power densities well above those achievable with radioisotopic thermoelectric generator (RTG) systems. An efficiency of 14.4 percent and system specific power of 9.25 watts/kg were predicted for a system with sixteen GPHS (general purpose heat source) sources operating at 1100 C. The models also showed a 500 watt system power by the strontium-90 isotope at 1200 C at an efficiency of 17.0 percent and a system specific power of 11.8 watts/kg. The key to this level of performance is a high-quality photovoltaic cell with narrow bandgap and a reflective rear contact. Recent work at Boeing on GaSb cells and transparent back GaAs cells indicate that such a cell is well within reach.

Validation Database Based Thermal Analysis of an Advanced RPS Concept

NASA Technical Reports Server (NTRS)

Balint, Tibor S.; Emis, Nickolas D.

2006-01-01

Advanced RPS concepts can be conceived, designed and assessed using high-end computational analysis tools. These predictions may provide an initial insight into the potential performance of these models, but verification and validation are necessary and required steps to gain confidence in the numerical analysis results. This paper discusses the findings from a numerical validation exercise for a small advanced RPS concept, based on a thermal analysis methodology developed at JPL and on a validation database obtained from experiments performed at Oregon State University. Both the numerical and experimental configurations utilized a single GPHS module enabled design, resembling a Mod-RTG concept. The analysis focused on operating and environmental conditions during the storage phase only. This validation exercise helped to refine key thermal analysis and modeling parameters, such as heat transfer coefficients, and conductivity and radiation heat transfer values. Improved understanding of the Mod-RTG concept through validation of the thermal model allows for future improvements to this power system concept.

GPHS RTGs in Support of the Cassini RTG Program. Final Technical Report, January 11, 1991 - April 30, 1998

DOE R&D Accomplishments Database

1998-08-01

As noted in the historical summary, this program encountered a number of changes in direction, schedule, and scope over the period 11 January 1991 to 31 December 1998. The report provides a comprehensive summary of all the varied aspects of the program over its seven and a quarter years, and highlights those aspects that provide information beneficial to future radioisotope programs. In addition to summarizing the scope of the Cassini GPHS RTG Program provided as background, the introduction includes a discussion of the scope of the final report and offers reference sources for information on those topics not covered. Much of the design heritage of the GPHS RTG comes from the Multi Hundred Watt (MHW) RTGs used on the Lincoln Experimental Satellites (LES) 8/9 and Voyager spacecraft. The design utilized for the Cassini program was developed, in large part, under the GPHS RTG program which produced the Galileo and Ulysses RTGs. Reports from those programs included detailed documentation of the design, development, and testing of converter components and full converters that were identical to, or similar to, components used in the Cassini program.

KSC-97PC1069

NASA Image and Video Library

1997-07-18

Jet Propulsion Laboratory (JPL) workers David Rice, at left, and Johnny Melendez rotate a radioisotope thermoelectric generator (RTG) to the horizontal position on a lift fixture in the Payload Hazardous Servicing Facility. The RTG is one of three generators which will provide electrical power for the Cassini spacecraft mission to the Saturnian system. The RTGs will be installed on the powered-up spacecraft for mechanical and electrical verification testing. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate far from the Sun where solar power systems are not feasible. The Cassini mission is scheduled for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed for NASA by JPL

KSC-97PC1088

NASA Image and Video Library

1997-07-18

This radioisotope thermoelectric generator (RTG), at center, is ready for electrical verification testing now that it has been installed on the Cassini spacecraft in the Payload Hazardous Servicing Facility. A handling fixture, at far left, remains attached. This is the third and final RTG to be installed on Cassini for the prelaunch tests. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate at great distances from the Sun where solar power systems are not feasible. The Cassini mission is targeted for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle

Apollo 12 Mission image - Alan Bean unloads ALSEP RTG fuel element

NASA Image and Video Library

1969-11-19

AS12-46-6790 (19 Nov. 1969) --- Astronaut Alan L. Bean, lunar module pilot, is photographed at quadrant II of the Lunar Module (LM) during the first Apollo 12 extravehicular activity (EVA) on the moon. This picture was taken by astronaut Charles Conrad Jr., commander. Here, Bean is using a fuel transfer tool to remove the fuel element from the fuel cask mounted on the LM's descent stage. The fuel element was then placed in the Radioisotope Thermoelectric Generator (RTG), the power source for the Apollo Lunar Surface Experiments Package (ALSEP) which was deployed on the moon by the two astronauts. The RTG is next to Bean's right leg. While astronauts Conrad and Bean descended in the LM "Intrepid" to explore the Ocean of Storms region of the moon, astronaut Richard F. Gordon Jr., command module pilot, remained with the Command and Service Modules (CSM) "Yankee Clipper" in lunar orbit.

Inadvertent Earth Reentry Breakup Analysis for the New Horizons Mission

NASA Technical Reports Server (NTRS)

Ling, Lisa M.; Salama, Ahmed; Ivanov, Mark; McRonald, Angus

2007-01-01

The New Horizons (NH) spacecraft was launched in January 2006 aboard an Atlas V launch vehicle, in a mission to explore Pluto, its moons, and other bodies in the Kuiper Belt. The NH spacecraft is powered by a Radioisotope Thermoelectric Generator (RTG) which encases multiple General Purpose Heat Source (GPHS) modules. Thus, a pre-launch vehicle breakup analysis for an inadvertent atmospheric reentry in the event of a launch failure was required to assess aerospace nuclear safety and for launch contingency planning. This paper addresses potential accidental Earth reentries analyzed at the Jet Propulsion Laboratory (JPL) which may arise during the ascent to parking orbit, resulting in a suborbital reentry, as well as a departure from parking orbit, resulting in an orbital reentry.

Astronaut John Young stands at ALSEP deployment site during first EVA

NASA Technical Reports Server (NTRS)

1972-01-01

Astronaut John W. Young, commander of the Apollo 16 lunar landing mission, stands at the Apollo Lunar Surface Experiments Package (ALSEP) deployment site during the first Apollo 16 extravehicular activity (EVA-1) at the Descartes landing site. The components of the ALSEP are in the background. The lunar surface drill is just behind and to the right of Young. The drill's rack and bore stems are to the left. The three sensor Lunar Surface Magnetometer is beyond the rack. The dark object in the right background is the Radioisotope Thermoelectric Generator (RTG). Between the RTG and the drill is the Heat Flow Experiment. A part of the Central Station is at the right center edge of the picture. This photograph was taken by Astronaut Charles M. Duke Jr., lunar module pilot.

Cassini's RTGs undergo mechanical and electrical verification tests in the PHSF

NASA Technical Reports Server (NTRS)

1997-01-01

This radioisotope thermoelectric generator (RTG), at center, is ready for electrical verification testing now that it has been installed on the Cassini spacecraft in the Payload Hazardous Servicing Facility. A handling fixture, at far left, remains attached. This is the third and final RTG to be installed on Cassini for the prelaunch tests. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate at great distances from the Sun where solar power systems are not feasible. The Cassini mission is targeted for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle.

RTG Safety Tests

NASA Technical Reports Server (NTRS)

1989-01-01

The primary objective of STS-34 was to launch Galileo on its trip to Jupiter. The Galileo spacecraft contains two Radioisotope Thermoelectric Generators (RTG), which contains plutonium. This videotape shows and the accompanying material explains the tests that the RTG containment vessel has been subjected to, and the results of the tests. The videotape shows the trajectory of the Galileo spacecraft, a cutaway view of an RTG, the Plutonium-238 fuel capsule, and seven of the tests on the RTG.

New Horizons Launch Contingency Effort

NASA Astrophysics Data System (ADS)

Chang, Yale; Lear, Matthew H.; McGrath, Brian E.; Heyler, Gene A.; Takashima, Naruhisa; Owings, W. Donald

2007-01-01

On 19 January 2006 at 2:00 PM EST, the NASA New Horizons spacecraft (SC) was launched from the Cape Canaveral Air Force Station (CCAFS), FL, onboard an Atlas V 551/Centaur/STAR™ 48B launch vehicle (LV) on a mission to explore the Pluto Charon planetary system and possibly other Kuiper Belt Objects. It carried a single Radioisotope Thermoelectric Generator (RTG). As part of the joint NASA/US Department of Energy (DOE) safety effort, contingency plans were prepared to address the unlikely events of launch accidents leading to a near-pad impact, a suborbital reentry, an orbital reentry, or a heliocentric orbit. As the implementing organization. The Johns Hopkins University Applied Physics Laboratory (JHU/APL) had expanded roles in the New Horizons launch contingency effort over those for the Cassini mission and Mars Exploration Rovers missions. The expanded tasks included participation in the Radiological Control Center (RADCC) at the Kennedy Space Center (KSC), preparation of contingency plans, coordination of space tracking assets, improved aerodynamics characterization of the RTG's 18 General Purpose Heat Source (GPHS) modules, and development of spacecraft and RTG reentry breakup analysis tools. Other JHU/APL tasks were prediction of the Earth impact footprints (ElFs) for the GPHS modules released during the atmospheric reentry (for purposes of notification and recovery), prediction of the time of SC reentry from a potential orbital decay, pre-launch dissemination of ballistic coefficients of various possible reentry configurations, and launch support of an Emergency Operations Center (EOC) on the JHU/APL campus. For the New Horizons launch, JHU/APL personnel at the RADCC and at the EOC were ready to implement any real-time launch contingency activities. A successful New Horizons launch and interplanetary injection precluded any further contingency actions. The New Horizons launch contingency was an interagency effort by several organizations. This paper describes JHU/APL's roles and responsibilities in the launch contingency effort, and the specific tasks to fulfill those responsibilities. The overall effort contributed to mission safety and demonstrated successful cooperation between several agencies.

Feasibility investigation of the Accelerated Skill Acquisition Program (ASAP): insights into reach-to-grasp coordination of individuals with postacute stroke.

PubMed

Tretriluxana, Jarugool; Runnarong, Nuttakarn; Tretriluxana, Suradej; Prayoonwiwat, Naraporn; Vachalathiti, Roongtiwa; Winstein, Carolee

2013-01-01

Skill acquisition, capacity building, and motivational enhancements are the basis of the Accelerated Skill Acquisition Program (ASAP) and form the foundation for effective incorporation of the paretic upper extremity into life activities. This is the first phase I trial to deliver ASAP during the postacute interval in mildly to moderately impaired stroke survivors and to include an assessment of paretic reach-to-grasp (RTG) coordination using RTG task and cross-correlation analyses. Two baseline and posttreatment evaluations consisted of RTG actions, the Wolf Motor Function Test (WMFT), and the Stroke Impact Scale (SIS). An individualized arm therapy program using ASAP principles was administered for a total of 30 hours, 2 hours per day, for 2 to 4 days per week over 5 weeks. Dependent measures were kinematics of RTG actions, RTG coordination, total time score of WMFT, and stroke recovery score of SIS. All participants tolerated ASAP well, and none reported any adverse effects during or after the protocol. When the 2 baseline evaluations were compared, there were no changes in any RTG kinematics or RTG coordination. In contrast, after 30 hours of ASAP, total movement time and deceleration time of RTG actions markedly decreased, maximum reach (transport) velocity strikingly increased, and time of maximum aperture was accomplished later. Additionally, the maximal RTG correlation coefficient increased with a shorter associated time lag. A similar pattern was observed for the clinical outcome measures of WMFT and SIS. The findings demonstrate the feasibility of using an ASAP protocol for patients 1 to 3 months post stroke. Under ASAP, WMFT tasks and RTG actions were performed faster with higher peak transport velocity and a more coordinated RTG pattern. The next step is to determine whether the immediate gains in the skilled RTG actions persist 6 months alter.

Status of modular RTG technology

NASA Astrophysics Data System (ADS)

Hartman, Robert F.

Radioisotope thermoelectric generators (RTGs) have been employed safely and reliably since 1961 to provide spacecraft electrical power for various NASA and Department of Defense missions. Historically, RTG development, fabrication and qualification have been performed under the sponsorship of the Department of Energy's Office of Special Nuclear Projects and its predecessor groups. RTG technology improvement programs have been conducted over the years by the DOE to improve RTG efficiency and operating performance. The modular RTG design concept resulted from such a program and is currently being developed by the General Electric Company for the DOE.

KSC-97PC1091

NASA Image and Video Library

1997-07-19

Lockheed Martin Missile and Space Co. employees Joe Collingwood, at right, and Ken Dickinson retract pins in the storage base to release a radioisotope thermoelectric generator (RTG) in preparation for hoisting operations. This RTG and two others will be installed on the Cassini spacecraft for mechanical and electrical verification testing in the Payload Hazardous Servicing Facility. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate at great distances from the Sun where solar power systems are not feasible. The Cassini mission is targeted for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed by NASA’s Jet Propulsion Laboratory

KSC-97PC1093

NASA Image and Video Library

1997-07-19

Supported on a lift fixture, this radioisotope thermoelectric generator (RTG), at center, is hoisted from its storage base using the airlock crane in the Payload Hazardous Servicing Facility (PHSF). Jet Propulsion Laboratory (JPL) workers are preparing to install the RTG onto the Cassini spacecraft, in background at left, for mechanical and electrical verification testing. The three RTGs on Cassini will provide electrical power to the spacecraft on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate at great distances from the Sun where solar power systems are not feasible. The Cassini mission is targeted for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed by JPL

Astronaut John Young stands at ALSEP deployment site during first EVA

NASA Image and Video Library

1972-04-21

AS16-114-18388 (21 April 1972) --- Astronaut John W. Young, commander of the Apollo 16 lunar landing mission, stands at the Apollo Lunar Surface Experiments Package (ALSEP) deployment site during the first Apollo 16 extravehicular activity (EVA) at the Descartes landing site. The components of the ALSEP are in the background. The lunar surface drill is just behind and to the right of astronaut Young. The drill's rack and bore stems are to the left. The three-sensor Lunar Surface Magnetometer is beyond the rack. The dark object in the right background is the Radioisotope Thermoelectric Generator (RTG). Between the RTG and the drill is the Heat Flow Experiment. A part of the Central Station is at the right center edge of the picture. This photograph was taken by astronaut Charles M. Duke Jr., lunar module pilot.

Divergent branches of mitochondrial signaling regulate specific genes and the viability of specialized cell types of differentiated yeast colonies.

PubMed

Podholová, Kristýna; Plocek, Vítězslav; Rešetárová, Stanislava; Kučerová, Helena; Hlaváček, Otakar; Váchová, Libuše; Palková, Zdena

2016-03-29

Mitochondrial retrograde signaling mediates communication from altered mitochondria to the nucleus and is involved in many normal and pathophysiological changes, including cell metabolic reprogramming linked to cancer development and progression in mammals. The major mitochondrial retrograde pathway described in yeast includes three activators, Rtg1p, Rtg2p and Rtg3p, and repressors, Mks1p and Bmh1p/Bmh2p. Using differentiated yeast colonies, we show that Mks1p-Rtg pathway regulation is complex and includes three branches that divergently regulate the properties and fate of three specifically localized cell subpopulations via signals from differently altered mitochondria. The newly identified RTG pathway-regulated genes ATO1/ATO2 are expressed in colonial upper (U) cells, the cells with active TORC1 that metabolically resemble tumor cells, while CIT2 is a typical target induced in one subpopulation of starving lower (L) cells. The viability of the second L cell subpopulation is strictly dependent on RTG signaling. Additional co-activators of Rtg1p-Rtg3p specific to particular gene targets of each branch are required to regulate cell differentiation.

Thermal Energy Conversion Branch

NASA Technical Reports Server (NTRS)

Bielozer, Matthew C.; Schreiber, Jeffrey, G.; Wilson, Scott D.

2004-01-01

The Thermal Energy Conversion Branch (5490) leads the way in designing, conducting, and implementing research for the newest thermal systems used in space applications at the NASA Glenn Research Center. Specifically some of the most advanced technologies developed in this branch can be broken down into four main areas: Dynamic Power Systems, Primary Solar Concentrators, Secondary Solar Concentrators, and Thermal Management. Work was performed in the Dynamic Power Systems area, specifically the Stirling Engine subdivision. Today, the main focus of the 5490 branch is free-piston Stirling cycle converters, Brayton cycle nuclear reactors, and heat rejection systems for long duration mission spacecraft. All space exploring devices need electricity to operate. In most space applications, heat energy from radioisotopes is converted to electrical power. The Radioisotope Thermoelectric Generator (RTG) already supplies electricity for missions such as the Cassini Spacecraft. The focus of today's Stirling research at GRC is aimed at creating an engine that can replace the RTG. The primary appeal of the Stirling engine is its high system efficiency. Because it is so efficient, the Stirling engine will significantly reduce the plutonium fuel mission requirements compared to the RTG. Stirling is also being considered for missions such as the lunar/Mars bases and rovers. This project has focused largely on Stirling Engines of all types, particularly the fluidyne liquid piston engine. The fluidyne was developed by Colin D. West. This engine uses the same concepts found in any type of Stirling engine, with the exception of missing mechanical components. All the working components are fluid. One goal was to develop and demonstrate a working Stirling Fluidyne Engine at the 2nd Annual International Energy Conversion Engineering Conference in Providence, Rhode Island.

Quaternized Q-PEIPAAm-Based Antimicrobial Reverse Thermal Gel: A Potential for Surgical Incision Drapes.

PubMed

Bortot, Maria; Laughter, Melissa Ronni; Stein, Madia; Rocker, Adam; Patel, Vikas; Park, Daewon

2018-05-16

A quaternized reverse thermal gel (RTG) aimed at replacing current surgical incision drapes (SIDs) was designed and characterized. The antimicrobial efficacy of the quaternized RTG was analyzed using both in vitro and in vivo models and was compared to standard SIDs. Polymer characterization was completed using both nuclear magnetic resonance ( 1 H NMR) and lower critical solution temperature (LCST) analysis. Biocompatibility was assessed using a standard cell viability assay. The in vitro antimicrobial efficacy of the polymer was analyzed against four common bacteria species using a time-kill test. The in vivo antimicrobial efficacy of the polymer and standard SIDs were compared using a murine model aimed at mimicking surgical conditions. NMR confirmed the polymer structure and presence of quaternized groups and alkyl chains. The polymer displayed a LCST of 34 °C and a rapid rate of gelation, allowing stable gel formation when applied to skin. Once quaternized, the polymer displayed an increase in kill-rate of bacteria compared to unquaternized polymer. In experiments aimed at mimicking surgical conditions, the quaternized polymer showed statistically comparable bacteria-killing capacity to the standard SID and even surpassed the SID for killing capacity at various time points. A novel approach to replacing current SIDs was developed using an antimicrobial polymer system with RTG properties. The RTG properties of this polymer maintain a liquid state at low temperatures and a gel upon heating, allowing this polymer to form a tight coating when applied to skin. Furthermore, this polymer achieved excellent antimicrobial properties in both in vitro and in vivo models. With further optimization, this polymer system has the potential to replace and streamline presurgical patient preparations through its easy application and beneficial antimicrobial properties.

Characteristics and Impact Factors of Renal Threshold for Glucose Excretion in Patients with Type 2 Diabetes Mellitus.

PubMed

Yue, Xiao Dan; Wang, Jing Yu; Zhang, Xin Rong; Yang, Ju Hong; Shan, Chun Yan; Zheng, Miao Yan; Ren, Hui Zhu; Zhang, Yi; Yang, Shao Hua; Guo, Zhen Hong; Chang, Bai; Chang, Bao Cheng

2017-04-01

Sodium glucose co-transporter 2 (SGLT-2) inhibitors are newly developed but promising medicine for type 2 diabetes. However, patients with a different renal threshold for glucose excretion (RT(G)) may have a different reaction to this medicine. Therefore, the objective of this study was to investigate the characteristics of RT(G) and its impact factors in patients with type 2 diabetes mellitus (T2DM). The clinical and laboratory data of 36 healthy individuals and 168 in-hospital patients with T2DM were collected and analyzed, RT(G) was calculated using blood glucose (BG) measured by dynamic BG monitoring, urinary glucose excretion (UGE) and estimated glomerular filtration rate (eGFR). The characteristics of RT(G) were investigated. The risk factors for high RT(G) were analyzed using non-conditional logistic regression analysis. Our results found that RT(G) of the T2DM group was higher than that of the healthy individuals (P < 0.05); and 22.22% from the healthy individuals group but 58.33% from the T2DM group had high RT(G). Age, duration of diabetes, body mass index (BMI), and homeostasis model assessment insulin resistance index (HOMA-IR) were independently associated with high RT(G) (P < 0.05). Further stratified analysis revealed that RT(G) in T2DM patients increased with age, duration of diabetes, and BMI. In conclusion, RT(G) is increased in patients with T2DM, especially in those with longer diabetic duration, higher BMI, and those who are older. Therefore, these patients may be more sensitive to SGLT-2 inhibitors. © 2017 The Korean Academy of Medical Sciences.

Recovery of 238PuO2 by Molten Salt Oxidation Processing of 238PuO2 Contaminated Combustibles (Part II)

NASA Astrophysics Data System (ADS)

Remerowski, Mary Lynn; Dozhier, C.; Krenek, K.; VanPelt, C. E.; Reimus, M. A.; Spengler, D.; Matonic, J.; Garcia, L.; Rios, E.; Sandoval, F.; Herman, D.; Hart, R.; Ewing, B.; Lovato, M.; Romero, J. P.

2005-02-01

Pu-238 heat sources are used to fuel radioisotope thermoelectric generators (RTG) used in space missions. The demand for this fuel is increasing, yet there are currently no domestic sources of this material. Much of the fuel is material reprocessed from other sources. One rich source of Pu-238 residual material is that from contaminated combustible materials, such as cheesecloth, ion exchange resins and plastics. From both waste minimization and production efficiency standpoints, the best solution is to recover this material. One way to accomplish separation of the organic component from these residues is a flameless oxidation process using molten salt as the matrix for the breakdown of the organic to carbon dioxide and water. The plutonium is retained in the salt, and can be recovered by dissolution of the carbonate salt in an aqueous solution, leaving the insoluble oxide behind. Further aqueous scrap recovery processing is used to purify the plutonium oxide. Recovery of the plutonium from contaminated combustibles achieves two important goals. First, it increases the inventory of Pu-238 available for heat source fabrication. Second, it is a significant waste minimization process. Because of its thermal activity (0.567 W per gram), combustibles must be packaged for disposition with much lower amounts of Pu-238 per drum than other waste types. Specifically, cheesecloth residues in the form of pyrolyzed ash (for stabilization) are being stored for eventual recovery of the plutonium.

Recovery of 238PuO2 by Molten Salt Oxidation Processing of 238PuO2 Contaminated Combustibles (Part II)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Remerowski, Mary Lynn; Dozhier, C.; Krenek, K.

2005-02-06

Pu-238 heat sources are used to fuel radioisotope thermoelectric generators (RTG) used in space missions. The demand for this fuel is increasing, yet there are currently no domestic sources of this material. Much of the fuel is material reprocessed from other sources. One rich source of Pu-238 residual material is that from contaminated combustible materials, such as cheesecloth, ion exchange resins and plastics. From both waste minimization and production efficiency standpoints, the best solution is to recover this material. One way to accomplish separation of the organic component from these residues is a flameless oxidation process using molten salt asmore » the matrix for the breakdown of the organic to carbon dioxide and water. The plutonium is retained in the salt, and can be recovered by dissolution of the carbonate salt in an aqueous solution, leaving the insoluble oxide behind. Further aqueous scrap recovery processing is used to purify the plutonium oxide. Recovery of the plutonium from contaminated combustibles achieves two important goals. First, it increases the inventory of Pu-238 available for heat source fabrication. Second, it is a significant waste minimization process. Because of its thermal activity (0.567 W per gram), combustibles must be packaged for disposition with much lower amounts of Pu-238 per drum than other waste types. Specifically, cheesecloth residues in the form of pyrolyzed ash (for stabilization) are being stored for eventual recovery of the plutonium.« less

Munitions Detection Using Unmanned Underwater Vehicles Equipped with Advanced Sensors

DTIC Science & Technology

2012-06-29

buried target. The RTG is a small passive magnetic sensor using fluxgate magnetometers measuring 3- orthogonal magnetic-field vector components at 3...surveys. Figure 6 shows the RTG magnetic sensor in both an open (showing the fluxgate magnetometers ) and enclosed state (mode for integration onto...7.6 Real-time Tracking Gradiometer (RTG) System The RTG is a small passive magnetic sensor using fluxgate magnetometers measuring 3- orthogonal

Cassini's RTGs undergo mechanical and electrical verification tests in the PHSF

NASA Technical Reports Server (NTRS)

1997-01-01

Lockheed Martin Missile and Space Co. employees Joe Collingwood, at right, and Ken Dickinson retract pins in the storage base to release a radioisotope thermoelectric generator (RTG) in preparation for hoisting operations. This RTG and two others will be installed on the Cassini spacecraft for mechanical and electrical verification testing in the Payload Hazardous Servicing Facility. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate at great distances from the Sun where solar power systems are not feasible. The Cassini mission is targeted for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed by NASA's Jet Propulsion Laboratory.

KSC-97pc1065

NASA Image and Video Library

1997-07-18

Jet Propulsion Laboratory (JPL) workers prepare the installation cart (atop the platform) for removal of a radioisotope thermoelectric generator (RTG) from the adjacent Cassini spacecraft. This is the second of three RTGs being removed from Cassini after undergoing mechanical and electrical verification tests in the Payload Hazardous Servicing Facility. The third RTG to be removed is in background at left. The three RTGs will then be temporarily stored before being re-installed for flight. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate far from the Sun where solar power systems are not feasible. The Cassini mission is scheduled for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed for NASA by JPL

Detection of fibrin generation alterations in dogs with haemangiosarcoma using resonance thrombography.

PubMed

Mischke, R; Wohlsein, P; Schoon, H-A

2005-01-01

The objective of the study was to examine the alterations of fibrin generation in dogs with haemangiosarcoma using resonance thrombography. The second objective was to evaluate the sensitivity of this method for the detection of hypofibrinogenaemia and/or increased fibrin(ogen) degradation product (FDP) concentration. Resonance thrombogram (RTG) measurements with two different instruments were performed in 30 unselected dogs with haemangiosarcoma, 14 of which had decreased fibrinogen and 28 of which had an increased FDP concentration (p<0.0001). The RTG-reaction time was less sensitive than the fibrin formation time (RTG-f) and fibrin amplitude (RTG-F). The RTG-f and RTG-F indicated reliably a decrease in fibrinogen concentration (sensitivity: 0.93). The sensitivity of detection of increased FDP levels was considerably higher than that of thrombin time. However, false-negative results were found even at FDP concentrations > or =120 mg/l, especially in cases with high fibrinogen level. Both machines showed similar sensitivity. The results of this study indicate that canine haemangiosarcoma is frequently associated with severe alterations of fibrin generation due to low fibrinogen and high FDP levels leading to distinct RTG abnormalities. The global test RTG reacts sensitively to a decreased fibrinogen level whereas its accuracy to detect FDP concentrations occurring under pathophysiological conditions is limited. A significant alteration of fibrin generation induced by FDPs may not occur until the serum FDP concentration exceeds 60 mg/l.

Nuclear energy technology

NASA Technical Reports Server (NTRS)

Buden, David

1992-01-01

An overview of space nuclear energy technologies is presented. The development and characteristics of radioisotope thermoelectric generators (RTG's) and space nuclear power reactors are discussed. In addition, the policy and issues related to public safety and the use of nuclear power sources in space are addressed.

Computer predictions of ground storage effects on performance of Galileo and ISPM generators

NASA Technical Reports Server (NTRS)

Chmielewski, A.

1983-01-01

Radioisotope Thermoelectric Generators (RTG) that will supply electrical power to the Galileo and International Solar Polar Mission (ISPM) spacecraft are exposed to several degradation mechanisms during the prolonged ground storage before launch. To assess the effect of storage on the RTG flight performance, a computer code has been developed which simulates all known degradation mechanisms that occur in an RTG during storage and flight. The modeling of these mechanisms and their impact on the RTG performance are discussed.

Virological and immunological responses to raltegravir and dolutegravir in the gut-associated lymphoid tissue of HIV-infected men and women.

PubMed

Weber, Michael D; Andrews, Elizabeth; Prince, Heather A; Sykes, Craig; Rosen, Elias P; Bay, Camden; Shaheen, Nicholas J; Madanick, Ryan D; Dellon, Evan S; De Paris, Kristina; Nelson, Julie Ae; Gay, Cynthia L; Kashuba, Angela Dm

2018-05-01

Raltegravir (RTG) and dolutegravir (DTG) have different pharmacokinetic patterns in the gastrointestinal tract. To determine if this results in pharmacodynamic differences, we compared HIV RNA, HIV DNA, and immunological markers in gut-associated lymphoid tissue (GALT) of HIV-infected participants receiving RTG or DTG with tenofovir+emtricitabine (TDF/FTC). GALT specimens from the terminal ileum, splenic flexure, and rectum were obtained by colonoscopy at a single time point in 20 adults treated with RTG (n=10) or DTG (n=10) with HIV RNA <50 copies/mL. Flow cytometry, drug concentrations, and HIV RNA and DNA were analyzed in tissue. CD4/8 + T cells were tested for γδ TCR, and markers of T cell activation and exhaustion. Data are reported as median (Q1,Q3). 15 men and 5 women were enrolled. There was no difference in time since HIV diagnosis for those on RTG [9.5 (4-22) yr] and DTG [17 (1-24) yr] (p = 0.6), although time on RTG [5.4 (2.3-6.7) yr] was greater than DTG [1.0 (0.1-1.5) yr] (P < 0.001). Concentrations of RTG and DTG in rectal tissue (RT) were similar to previous reports: median tissue:plasma ratio was 11.25 for RTG and 0.44 for DTG. RNA:DNA ratios were [1.14 (0.18-5.10)] for the RTG group and [0.90 (0.30-18.87)] for the DTG group (p = 0.95). No differences (p ≥ 0.1) between CD4 + and CD8 + T cell markers were found. RTG produced higher tissue exposures than DTG, but no significant differences in GALT HIV RNA, DNA, or most immunologic markers were observed.

Lunar Surface Stirling Power Systems Using Isotope Heat Sources

NASA Technical Reports Server (NTRS)

Schmitz, Paul C.; Penswick, L. Barry; Shaltens, Richard K.

2010-01-01

For many years, NASA has used the decay of plutonium-238 (Pu-238) (in the form of the General Purpose Heat Source (GPHS)) as a heat source for Radioisotope Thermoelectric Generators (RTGs), which have provided electrical power for many NASA missions. While RTGs have an impressive reliability record for the missions in which they have been used, their relatively low thermal to electric conversion efficiency and the scarcity of plutonium-238 (Pu-238) has led NASA to consider other power conversion technologies. NASA is considering returning both robotic and human missions to the lunar surface and, because of the long lunar nights (14.75 Earth days), isotope power systems are an attractive candidate to generate electrical power. NASA is currently developing the Advanced Stirling Radioisotope Generator (ASRG) as a candidate higher efficiency power system that produces greater than 160 W with two GPHS modules at the beginning of life (BOL) (32% efficiency). The ASRG uses the same Pu-238 GPHS modules, which are used in RTG, but by coupling them to a Stirling convertor provides a four-fold reduction in the number of GPHS modules. This study considers the use of americium-241 (Am-241) as a substitute for the Pu-238 in Stirling- convertor-based Radioisotope Power Systems (RPS) for power levels from tens of watts to 5 kWe. The Am-241 is used as a substitute for the Pu-238 in GPHS modules. Depending on power level, different Stirling heat input and removal systems are modeled. It was found that substituting Am-241 GPHS modules into the ASRG reduces power output by about one-fifth while maintaining approximately the same system mass. In order to obtain the nominal 160 W of electrical output of the Pu-238 ASRG requires 10 Am-241 GPHS modules. Higher power systems require changing from conductive coupling heat input and removal from the Stirling convertor to either pumped loops or heat pipes. Liquid metal pumped loops are considered as the primary heat transportation on the hot end and water pumped loop/heat pipe radiator is considered for the heat rejection side for power levels above 1 kWe.

Pressurized Lunar Rover (PLR)

NASA Technical Reports Server (NTRS)

Creel, Kenneth; Frampton, Jeffrey; Honaker, David; Mcclure, Kerry; Zeinali, Mazyar; Bhardwaj, Manoj; Bulsara, Vatsal; Kokan, David; Shariff, Shaun; Svarverud, Eric

1992-01-01

The objective of this project was to design a manned pressurized lunar rover (PLR) for long-range transportation and for exploration of the lunar surface. The vehicle must be capable of operating on a 14-day mission, traveling within a radius of 500 km during a lunar day or within a 50-km radius during a lunar night. The vehicle must accommodate a nominal crew of four, support two 28-hour EVA's, and in case of emergency, support a crew of six when near the lunar base. A nominal speed of ten km/hr and capability of towing a trailer with a mass of two mt are required. Two preliminary designs have been developed by two independent student teams. The PLR 1 design proposes a seven meter long cylindrical main vehicle and a trailer which houses the power and heat rejection systems. The main vehicle carries the astronauts, life support systems, navigation and communication systems, lighting, robotic arms, tools, and equipment for exploratory experiments. The rover uses a simple mobility system with six wheels on the main vehicle and two on the trailer. The nonpressurized trailer contains a modular radioisotope thermoelectric generator (RTG) supplying 6.5 kW continuous power. A secondary energy storage for short-term peak power needs is provided by a bank of lithium-sulfur dioxide batteries. The life support system is partly a regenerative system with air and hygiene water being recycled. A layer of water inside the composite shell surrounds the command center allowing the center to be used as a safe haven during solar flares. The PLR 1 has a total mass of 6197 kg. It has a top speed of 18 km/hr and is capable of towing three metric tons, in addition to the RTG trailer. The PLR 2 configuration consists of two four-meter diameter, cylindrical hulls which are passively connected by a flexible passageway, resulting in the overall vehicle length of 11 m. The vehicle is driven by eight independently suspended wheels. The dual-cylinder concept allows articulated as well as double Ackermann steering. The primary power of 8 kW is supplied by a dynamic isotope system using a closed Brayton cycle with a xenon-hydrogen mixture as the working fluid. A sodium-sulfur battery serves as the secondary power source. Excess heat produced by the primary power system and other rover systems is rejected by radiators located on the top of the rear cylinder. The total mass of the PLR 2 is 7015 kg. Simplicity and low total weight have been the driving principles behind the design of PLR 1. The overall configuration consists of a 7-m-long, 3-m-diameter cylindrical main vehicle and a two-wheeled trailer. The cylinder of the main body is capped by eight-section, faceted, semi-hemispherical ends. The trailer contains the RTG power source and is not pressurized. The shell of the main body is constructed of a layered carbon fiber/foam/Kevlar sandwich structure. Included in the shell is a layer of water for radiation protection. The layer of water extends from the front of the rover over the crew compartment and creates a safe haven for the crew during a solar flare-up. The carbon fiber provides the majority of the strength and stiffness and the Kevlar provides protection from micrometeoroids. The Kevlar is covered with a gold foil and multi-layer insulation (MLI) to reduce radiation degradation and heat transfer through the wall. A thin thermoplastic layer seals the fiber and provides additional strength.

Pressurized Lunar Rover (PLR)

NASA Astrophysics Data System (ADS)

Creel, Kenneth; Frampton, Jeffrey; Honaker, David; McClure, Kerry; Zeinali, Mazyar; Bhardwaj, Manoj; Bulsara, Vatsal; Kokan, David; Shariff, Shaun; Svarverud, Eric

The objective of this project was to design a manned pressurized lunar rover (PLR) for long-range transportation and for exploration of the lunar surface. The vehicle must be capable of operating on a 14-day mission, traveling within a radius of 500 km during a lunar day or within a 50-km radius during a lunar night. The vehicle must accommodate a nominal crew of four, support two 28-hour EVA's, and in case of emergency, support a crew of six when near the lunar base. A nominal speed of ten km/hr and capability of towing a trailer with a mass of two mt are required. Two preliminary designs have been developed by two independent student teams. The PLR 1 design proposes a seven meter long cylindrical main vehicle and a trailer which houses the power and heat rejection systems. The main vehicle carries the astronauts, life support systems, navigation and communication systems, lighting, robotic arms, tools, and equipment for exploratory experiments. The rover uses a simple mobility system with six wheels on the main vehicle and two on the trailer. The nonpressurized trailer contains a modular radioisotope thermoelectric generator (RTG) supplying 6.5 kW continuous power. A secondary energy storage for short-term peak power needs is provided by a bank of lithium-sulfur dioxide batteries. The life support system is partly a regenerative system with air and hygiene water being recycled. A layer of water inside the composite shell surrounds the command center allowing the center to be used as a safe haven during solar flares. The PLR 1 has a total mass of 6197 kg. It has a top speed of 18 km/hr and is capable of towing three metric tons, in addition to the RTG trailer. The PLR 2 configuration consists of two four-meter diameter, cylindrical hulls which are passively connected by a flexible passageway, resulting in the overall vehicle length of 11 m. The vehicle is driven by eight independently suspended wheels. The dual-cylinder concept allows articulated as well as double Ackermann steering. The primary power of 8 kW is supplied by a dynamic isotope system using a closed Brayton cycle with a xenon-hydrogen mixture as the working fluid.

Lack of effect of ezogabine/retigabine on the pharmacokinetics of digoxin in healthy individuals: results from a drug–drug interaction study

PubMed Central

Tompson, Debra J; Crean, Christopher S; Buraglio, Mauro; Arumugham, Thangam

2014-01-01

Introduction The potential for ezogabine/retigabine (EZG/RTG) and its N-acetyl metabolite (NAMR) to inhibit the transporter protein P-glycoprotein-(P-gp)-mediated digoxin transport was tested in vitro. EZG/RTG did not inhibit P-gp. However, NAMR inhibited P-gp in a concentration-dependent manner. Based on these in vitro results, NAMR had the potential to inhibit P-gp at therapeutic doses of EZG/RTG (600–1,200 mg/day). As digoxin has a narrow therapeutic index, inhibition of digoxin clearance may have an impact on its safety. Methods An open-label, single-center, two session, fixed-sequence study was conducted to assess the effect of co-administration of therapeutic doses of EZG/RTG on digoxin pharmacokinetics in healthy adults. In session 1, subjects received a single dose of digoxin 0.25 mg. In session 2, EZG/RTG was up-titrated over 6 weeks. Digoxin 0.25 mg was co-administered at EZG/RTG steady-state doses of 600, 900, and, based on tolerability, 1,050/1,200 mg/day. Blood samples were collected over 144 hours for determination of digoxin, EZG/RTG, and NAMR concentrations. Urine samples were collected over 48 hours for determination of digoxin concentrations. Results Of 30 subjects enrolled, 29 were included in the pharmacokinetic analysis. Compared with digoxin alone, co-administration with EZG/RTG led to small increases in the digoxin plasma area under the concentration–time curve (AUC)0–120 at doses of 600, 900, and 1,050/1,200 mg (geometric mean ratio 1.08, 90% confidence interval [CI] 1.01–1.15; 1.18, 90% CI 1.10–1.27; 1.13, 90% CI 1.05–1.21, respectively). Safety was consistent with previous repeat-dose studies of EZG/RTG in healthy subjects. Conclusion Co-administration of EZG/RTG across the therapeutic range resulted in small, non-dose-dependent and non-clinically relevant increases in digoxin systemic exposure, suggesting that digoxin dose adjustment is not necessary. PMID:25342921

Induction of antiviral genes, Mx and vig-1, by dsRNA and Chum salmon reovirus in rainbow trout monocyte/macrophage and fibroblast cell lines.

PubMed

DeWitte-Orr, Stephanie J; Leong, Jo-Ann C; Bols, Niels C

2007-09-01

The expression of potential antiviral genes, Mx1, Mx2, Mx3 and vig-1, was studied in two rainbow trout cell lines: monocyte/macrophage RTS11 and fibroblast-like RTG-2. Transcripts were monitored by RT-PCR; Mx protein by Western blotting. In unstimulated cultures Mx1 and vig-1 transcripts were seen occasionally in RTS11 but rarely in RTG-2. A low level of Mx protein was seen in unstimulated RTS11 but not in RTG-2. In both cell lines, Mx and vig-1 transcripts were induced by a dsRNA, poly inosinic: poly cytidylic acid (poly IC), and by Chum salmon reovirus (CSV). Medium conditioned by cells previously exposed to poly IC or CSV and assumed to contain interferon (IFN) induced the antiviral genes in RTS11. However, RTG-2 responded only to medium conditioned by RTG-2 exposed previously to CSV. In both cell lines, poly IC and CSV induced Mx transcripts in the presence of cycloheximide, suggesting a direct induction mechanism, independent of IFN, was also possible. For CSV, ribavirin blocked induction in RTS11 but not in RTG-2, suggesting viral RNA synthesis was required for induction only in RTS11. In both RTS11 and RTG-2 cultures, Mx protein showed enhanced accumulation by 24h after exposure to poly IC and CSV, but subsequently Mx protein levels declined back to control levels in RTS11 but not in RTG-2. These results suggest that Mx can be regulated differently in macrophages and fibroblasts.

A novel design for a dose finding, safety, and drug interaction study of an antiepileptic drug (retigabine) in early clinical development.

PubMed

Sachdeo, Rajesh; Partiot, Arnaud; Biton, Victor; Rosenfeld, William E; Nohria, Virinder; Tompson, Debra; DeRossett, Sarah; Porter, Roger J

2014-06-01

To obtain information on the acceptable doses of the antiepileptic drug (AED) retigabine (RTG), the maximum tolerated dose (MTD), drug interactions, safety and tolerability, and preliminary evidence of efficacy when administered as adjunctive therapy and as monotherapy. Study 202 was an open-label, add-on study in patients with partial or generalized epilepsy treated with valproic acid (VPA), carbamazepine (CBZ), phenytoin (PHT), or topiramate (TPM) as monotherapy. Following baseline assessments, patients entered a dose titration phase of 28 – 56 days. The initial daily RTG dose was 100 or 200 mg (2 or 3 × daily). The RTG dose was increased every 1 - 2 weeks by 50 - 200 mg to a maximum of 1,600 mg/day. Once the RTG MTD had been attained, patients entered a 14-day maintenance period. Following this, the patient's background AED dose could be reduced, with the possibility of achieving RTG monotherapy. The final dosing regimen attained was maintained for an additional 14 days. Patients who completed study 202 could choose to continue treatment with RTG (with or without other AEDs) in study 208, the long-term extension of study 202. Safety assessments included adverse event (AE) monitoring, clinical laboratory evaluations, electrocardiograms, and physical and neurologic examinations. Patients' seizure diaries to assess the frequency and type of seizures, the percentage change in seizure rate, and the responder rate (>= 50% reduction in seizure rate from baseline) were evaluated. 60 patients (mean age 37.2, range 16 - 64 years) were enrolled in study 202, and 47 (78%) continued treatment with RTG in the extension study (208). In study 202, the most commonly reported AEs were: dizziness (53%), asthenia (42%), somnolence (33%), nausea (27%), speech disorder (27%), and tremor (27%). In the extension study, AEs were similar and included dizziness, somnolence, diplopia, feeling "drunk", confusion, fatigue, and dysarthria. The median percent reductions in 28-day seizure rate, relative to baseline in Studies 202 and 208, were ~ 20% and 47%, respectively. RTG did not alter the pharmacokinetics of the four monotherapy AEDs investigated. CBZ and PHT increased RTG clearance by 27% and 36%, respectively, whereas TPM and VPA had no effect on RTG clearance. Studies 202 and 208 provided critical information on RTG safety and tolerability, and reductions in seizure rates towards the design and conduct of subsequent pivotal clinical trials. Likewise, information regarding the appropriate dosage of RTG with VPA, CBZ, PHT, or TPM was obtained, which permitted the subsequent pivotal trials to be performed appropriately. *Currently at Shire Pharmaceuticals, Behavioral Health Business Unit, Wayne, PA, USA **Currently at University of Pennsylvania, Department of Neurology, Philadelphia, PA, USA.

Muscarinic Receptor-Dependent Long Term Depression in the Perirhinal Cortex and Recognition Memory are Impaired in the rTg4510 Mouse Model of Tauopathy.

PubMed

Scullion, Sarah E; Barker, Gareth R I; Warburton, E Clea; Randall, Andrew D; Brown, Jonathan T

2018-02-26

Neurodegenerative diseases affecting cognitive dysfunction, such as Alzheimer's disease and fronto-temporal dementia, are often associated impairments in the visual recognition memory system. Recent evidence suggests that synaptic plasticity, in particular long term depression (LTD), in the perirhinal cortex (PRh) is a critical cellular mechanism underlying recognition memory. In this study, we have examined novel object recognition and PRh LTD in rTg4510 mice, which transgenically overexpress tau P301L . We found that 8-9 month old rTg4510 mice had significant deficits in long- but not short-term novel object recognition memory. Furthermore, we also established that PRh slices prepared from rTg4510 mice, unlike those prepared from wildtype littermates, could not support a muscarinic acetylcholine receptor-dependent form of LTD, induced by a 5 Hz stimulation protocol. In contrast, bath application of the muscarinic agonist carbachol induced a form of chemical LTD in both WT and rTg4510 slices. Finally, when rTg4510 slices were preincubated with the acetylcholinesterase inhibitor donepezil, the 5 Hz stimulation protocol was capable of inducing significant levels of LTD. These data suggest that dysfunctional cholinergic innervation of the PRh of rTg4510 mice, results in deficits in synaptic LTD which may contribute to aberrant recognition memory in this rodent model of tauopathy.

Anti-melanogenic effects of resveratryl triglycolate, a novel hybrid compound derived by esterification of resveratrol with glycolic acid.

PubMed

Park, Soojin; Seok, Jin Kyung; Kwak, Jun Yup; Choi, Yun-Hyeok; Hong, Seong Su; Suh, Hwa-Jin; Park, Woncheol; Boo, Yong Chool

2016-07-01

Resveratrol is known to inhibit cellular melanin synthesis by multiple mechanisms. Glycolic acid (GA) is used in skin care products for its excellent skin penetration. The purpose of this study was to examine the anti-melanogenic effects of resveratryl triglycolate (RTG), a novel hybrid compound of resveratrol and GA, in comparison with resveratrol, GA, resveratryl triacetate (RTA) and arbutin. Resveratrol, RTG, and RTA inhibited the catalytic activity human tyrosinase (TYR) more potently than arbutin or GA did. Their cytotoxic and anti-melanogenic effects were examined using murine melanoma B16/F10 cells and human epidermal melanocytes (HEMs). The cytotoxicity of RTG was similar to that of resveratrol and RTA. RTG at 3-10 μM decreased melanin levels and cellular TYR activities in α-melanocyte-stimulating hormone-stimulated B16/F10 cells, and L-tyrosine-stimulated HEMs. RTG also suppressed mRNA and protein expression of TYR, tyrosinase-related protein 1, L-3,4-dihydroxyphenylalanine chrome tautomerase, and microphthalmia-associated transcription factor (MITF) in HEMs stimulated with L-tyrosine. This study suggests that, like resveratrol and RTA, RTG can attenuate cellular melanin synthesis effectively through the suppression of MITF-dependent expression of melanogenic enzymes and the inhibition of catalytic activity of TYR enzyme. RTG therefore has potential for use as a cosmeceutical ingredient for skin whitening.

KSC-10941f07

NASA Image and Video Library

1997-05-27

Jet Propulsion Laboratory (JPL) technicians finish mounting a thermal model of a radioisotope thermoelectric generator (RTG) on the installation cart which will be used to install the RTG in the Cassini spacecraft at Level 14 of Space Launch Complex 40, Cape Canaveral Air Station. The technicians use the thermal model to practice installation procedures. The three actual RTGs which will provide electrical power to Cassini on its 6.7-mile trip to the Saturnian system, and during its four-year mission at Saturn, are being tested and monitored in the Radioisotope Thermoelectric Generator Storage Building in KSC's Industrial Area. The RTGs use heat from the natural decay of plutonium to generate electric power. RTGs enable spacecraft to operate far from the Sun where solar power systems are not feasible. The RTGs on Cassini are of the same design as those flying on the already deployed Galileo and Ulysses spacecraft. The Cassini mission is targeted for an October 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed for NASA by JPL

Operational Readiness Review Plan for the Radioisotope Thermoelectric Generator Materials Production Tasks

DOE R&D Accomplishments Database

Cooper, R. H.; Martin, M. M.; Riggs, C. R.; Beatty, R. L.; Ohriner, E. K.; Escher, R. N.

1990-04-19

In October 1989, a US shuttle lifted off from Cape Kennedy carrying the spacecraft Galileo on its mission to Jupiter. In November 1990, a second spacecraft, Ulysses, will be launched from Cape Kennedy with a mission to study the polar regions of the sun. The prime source of power for both spacecraft is a series of radioisotope thermoelectric generators (RTGs), which use plutonium oxide (plutonia) as a heat source. Several of the key components in this power system are required to ensure the safety of both the public and the environment and were manufactured at Oak Ridge National Laboratory (ORNL) in the 1980 to 1983 period. For these two missions, Martin Marietta Energy Systems, Inc. (Energy Systems), will provide an iridium alloy component used to contain the plutonia heat source and a carbon composite material that serves as a thermal insulator. ORNL alone will continue to fabricate the carbon composite material. Because of the importance to DOE that Energy Systems deliver these high quality components on time, performance of an Operational Readiness Review (ORR) of these manufacturing activities is necessary. Energy Systems Policy GP 24 entitled "Operational Readiness Process" describes the formal and comprehensive process by which appropriate Energy Systems activities are to be reviewed to ensure their readiness. This Energy System policy is aimed at reducing the risks associated with mission success and requires a management approved "readiness plan" to be issued. This document is the readiness plan for the RTG materials production tasks.

Developing the next Generation of Education Researchers: UCLA's Experience with the Spencer Foundation Research Training Grant

ERIC Educational Resources Information Center

Dorr, Aimee; Arms, Emily; Hall, Valerie

2008-01-01

Background/Context: In the early 1990s, the Spencer Foundation instituted an Institutional Research Training Grant (RTG) program to improve the preparation of the next generation of education researchers. UCLA received an RTG in the first round of competition. Purpose/Objective/Research Question/Focus of Study: UCLA's Spencer RTG program sought to…

Design and performance of radioisotope space power systems based on OSC multitube AMTEC converter designs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schock, A.; Noravian, H.; Or, C.

1997-12-31

This paper extends the analytical procedure described in another paper in these proceedings to analyze a variety of compact and light-weight OSC-designed radioisotope-heated generators. Those generators employed General Purpose Heat Source (GPHS) modules and a converter containing sixteen AMTEC cells of OSC`s revised five-tube design with enhanced cell wall reflectivity described in a companion paper in these proceedings. OSC found that the performance of the generator is primarily a function of the thermal insulation between the outside of the generator`s 16 cells and the inside of its wall. After examining a variety of insulation options, it was found that themore » generator`s performance is optimized by employing a hybrid insulation system, in which the space between the cells is filled with fibrous Min-K insulation, and the generator walls are lined with tapered (i.e., graded-length) multifoil insulation. The OSC design results in a very compact generator, with eight AMTEC cells on each end of the heat source stack. The choice of the five-tube cells makes it possible to expand the BASE tube diameter without increasing the cell diameter. This is important because the eight cells mate well with the stacked GPHS modules. The OSC generator design includes a compliant heat source support and preload arrangement, to hold the heat source modules together during launch, and to maintain thermal contact conductance at the generator`s interfaces despite creep relaxation of its housing. The BOM and EOM (up to 15 years) performances of the revised generators were analyzed for two and three GPHS modules, both for fresh fuel and for aged fuel left over from a spare RTG (Radioisotope Thermoelectric Generator) fueled in 1982. The resulting power outputs were compared with JPL`s latest EOM power demand goals for the Pluto Express and Europa Orbiter missions, and with the generic goals of DOE`s Advanced Radioisotope Power System (ARPS) study. The OSC AMTEC designs yielded system efficiencies three to four times as high as present-generation RTGs.« less

Hunting Sea Mines with UUV-Based Magnetic and Electro-Optic Sensors

DTIC Science & Technology

2010-06-01

assembly of four 3-axis fluxgate magnetometers and (c) magnetometer package for underwater deployment in flooded body section. data are automatically...features the Real-time Tracking Gradiometer (RTG), which is a multi-channel tensor gradiometer using conventional fluxgate technology. Also in this...integrated together into a Bluefin12 AUV [5]. A. RTG Sensor Technology The RTG is a multi-channel tensor gradiometer using conventional fluxgate

KSC-2011-6731

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, the trailer transporting the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission arrives at the RTG storage facility (RTGF). The MMRTG is returning to the RTGF following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6732

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- At the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida, preparations are under way to offload the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission from the MMRTG trailer. The MMRTG is returning to the RTGF following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6744

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- The multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission is uncovered in the high bay of the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida. The MMRTG was returned to the RTGF following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6730

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission, secured inside the MMRTG trailer, makes its way between the Payload Hazardous Servicing Facility (PHSF) and the RTG storage facility. The MMRTG is being moved following a fit check on MSL's Curiosity rover in the PHSF. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

Transcriptional regulation of respiration in yeast metabolizing differently repressive carbon substrates.

PubMed

Fendt, Sarah-Maria; Sauer, Uwe

2010-02-18

Depending on the carbon source, Saccharomyces cerevisiae displays various degrees of respiration. These range from complete respiration as in the case of ethanol, to almost complete fermentation, and thus very low degrees of respiration on glucose. While many key regulators are known for these extreme cases, we focus here on regulators that are relevant at intermediate levels of respiration. We address this question by linking the functional degree of respiration to transcriptional regulation via enzyme abundances. Specifically, we investigated aerobic batch cultures with the differently repressive carbon sources glucose, mannose, galactose and pyruvate. Based on 13C flux analysis, we found that the respiratory contribution to cellular energy production was largely absent on glucose and mannose, intermediate on galactose and highest on pyruvate. In vivo abundances of 40 respiratory enzymes were quantified by GFP-fusions under each condition. During growth on the partly and fully respired substrates galactose and pyruvate, several TCA cycle and respiratory chain enzymes were significantly up-regulated. From these enzyme levels and the known regulatory network structure, we determined the probability for a given transcription factor to cause the coordinated expression changes. The most probable transcription factors to regulate the different degrees of respiration were Gcr1p, Cat8p, the Rtg-proteins and the Hap-complex. For the latter three ones we confirmed their importance for respiration by quantifying the degree of respiration and biomass yields in the corresponding deletion strains. Cat8p is required for wild-type like respiration, independent of its known activation of gluconeogenic genes. The Rtg-proteins and the Hap-complex are essential for wild-type like respiration under partially respiratory conditions. Under fully respiratory conditions, the Hap-complex, but not the Rtg-proteins are essential for respiration.

KSC-2011-6727

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, a forklift lifts the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission into the MMRTG trailer. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is being moved to the RTG storage facility following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6667

NASA Image and Video Library

2011-07-12

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission is enclosed in a protective mesh container, known as the "gorilla cage," for transport to the Payload Hazardous Servicing Facility (PHSF). The cage protects the MMRTG and allows any excess heat generated to dissipate into the air. In the PHSF, the MMRTG temporarily will be installed on the MSL rover, Curiosity, for a fit check but will be installed on the rover for launch at the pad. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Curiosity, MSL's car-sized rover, has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is planned for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Cory Huston

KSC-2011-6722

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- In the airlock of the Payload Hazardous Servicing Facility (PHSF) at NASA's Kennedy Space Center in Florida, t he multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission awaits transport to the RTG storage facility. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG was in the PHSF for a fit check on MSL's Curiosity rover. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6726

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- A forklift transfers the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission from the airlock of the Payload Hazardous Servicing Facility (PHSF) at NASA's Kennedy Space Center in Florida to the MMRTG trailer. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is being moved to the RTG storage facility following a fit check on MSL's Curiosity rover in the PHSF. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6735

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- A forklift moves the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission into the high bay of the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is returning to the RTGF following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6734

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- A forklift moves the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission from the MMRTG trailer to the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is returning to the RTGF following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6725

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- A forklift carrying the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission backs away from the airlock of the Payload Hazardous Servicing Facility (PHSF) at NASA's Kennedy Space Center in Florida. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is being moved to the RTG storage facility following a fit check on MSL's Curiosity rover in the PHSF. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6736

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- Department of Energy workers park the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission in the high bay of the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is returning to the RTGF following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6743

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida, the mesh container enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission is lifted from around the MMRTG. The container, known as the "gorilla cage," protects the MMRTG during transport and allows any excess heat generated to dissipate into the air. The cage is being removed following the return of the MMRTG to the RTGF from a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6721

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- A forklift approaches the airlock of the Payload Hazardous Servicing Facility (PHSF) at NASA's Kennedy Space Center in Florida where the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission awaits transport to the RTG storage facility. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG was in the PHSF for a fit check on MSL's Curiosity rover. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6723

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- A forklift moves into position to lift the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission from the floor of the Payload Hazardous Servicing Facility (PHSF) airlock at NASA's Kennedy Space Center in Florida. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is being transported to the RTG storage facility following a fit check on MSL's Curiosity rover in the PHSF. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6733

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- The multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission is lifted from the MMRTG trailer at the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is returning to the RTGF following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6717

NASA Image and Video Library

2011-07-13

CAPE CANAVERAL, Fla. -- In the airlock of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, Department of Energy employees prepare the support base of the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission for installation of the mesh container, known as the "gorilla cage." The cage, in the background at right, protects the MMRTG during transport and allows any excess heat generated to dissipate into the air. Transport of the MMRTG to the RTG storage facility follows the completion of the MMRTG fit check on the Curiosity rover. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Kim Shiflett

KSC-2011-6724

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- A forklift moves into position to lift the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission from the floor of the Payload Hazardous Servicing Facility (PHSF) airlock at NASA's Kennedy Space Center in Florida. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is being moved to the RTG storage facility following a fit check on MSL's Curiosity rover in the PHSF. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6728

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, a forklift lifts the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission into the MMRTG trailer. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is being moved to the RTG storage facility following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6675

NASA Image and Video Library

2011-07-12

CAPE CANAVERAL, Fla. -- Outside the RTG storage facility at NASA's Kennedy Space Center in Florida, the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission, enclosed in the protective mesh container known as the "gorilla cage," is strapped down inside the MMRTG trailer for transport to the Payload Hazardous Servicing Facility (PHSF). The cage protects the MMRTG and allows any excess heat generated to dissipate into the air. In the PHSF, the MMRTG temporarily will be installed on the MSL rover, Curiosity, for a fit check but will be installed on the rover for launch at the pad. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Curiosity, MSL's car-sized rover, has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is planned for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Cory Huston

KSC-2011-6729

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, preparations are under way to secure the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission in the MMRTG trailer. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is being moved to the RTG storage facility following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

Development of a New Generation of High-Temperature Thermoelectric Unicouples for Space Applications

NASA Technical Reports Server (NTRS)

Caillat, Thierry; Gogna, P.; Sakamoto, J.; Jewell, A.; Cheng, J.; Blair, R.; Fleurial, J. -P.; Ewell, R.

2006-01-01

RTG's have enabled surface and deep space missions since 1961: a) 26 flight missions without any RTG failures; and b) Mission durations in excess of 25 years. Future NASA missions require RTG s with high specific power and high efficiency, while retaining long life (> 14 years) and high reliability, (i.e. 6-8 W/kg, 10-15% efficiency). JPL in partnership with NASA-GRC, NASA-MSFC, DOE, Universities and Industry is developing advanced thermoelectric materials and converters to meet future NASA needs.

Management experience of an international venture in space The Ulysses mission

NASA Technical Reports Server (NTRS)

Yoshida, Ronald Y.; Meeks, Willis G.

1986-01-01

The management of the Ulysses project, a probe which will fly a solar polar orbit, is described. The 5-yr mission will feature a flyby of Jupiter to deflect the spacecraft into a high-inclination orbit. Data on the solar corona, solar wind, the sun-wind interface, the heliospheric magnetic field, solar and nonsolar cosmic rays, etc., will be gathered as a function of the solar latitude. NASA will track and control the probe with the Deep Space Network. JPL provides project management for NASA while the Directorate of Scientific Programs performs ESA management functions. The DOE will provide a radioisotope thermoelectric generator while NASA and ESA each supply half the scientific payload. A NASA-ESA Joint Working Group meets about twice per year to monitor the project and discuss the technical and scientific requirements. Safety issues and measures which are being addressed due to the presence of the Pu-238 heat source for the RTG are discussed.

Nucleotide Sequence of the blaRTG-2 (CARB-5) Gene and Phylogeny of a New Group of Carbenicillinases

PubMed Central

Choury, Daniele; Szajnert, Marie-France; Joly-Guillou, Marie-Laure; Azibi, Kemal; Delpech, Marc; Paul, Gérard

2000-01-01

We determined the nucleotide sequence of the bla gene for the Acinetobacter calcoaceticus β-lactamase previously described as CARB-5. Alignment of the deduced amino acid sequence with those of known β-lactamases revealed that CARB-5 possesses an RTG triad in box VII, as described for the Proteus mirabilis GN79 enzyme, instead of the RSG consensus characteristic of the other carbenicillinases. Phylogenetic studies showed that these RTG enzymes constitute a new, separate group, possibly ancestors of the carbenicillinase family. PMID:10722515

Analysis, optimization, and assessment of radioisotope thermophotovoltaic system design for an illustrative space mission

NASA Astrophysics Data System (ADS)

Schock, A.; Mukunda, M.; Or, C.; Summers, G.

1995-01-01

A companion paper presented at this conference described the design of a Radioisotope Thermophotovoltaic (RTPV) Generator for an illustrative space mission (Pluto Fast Flyby). It presented a detailed design of an integrated system consisting of a radioisotope heat source, a thermophotovoltaic converter, and an optimized heat rejection system. The present paper describes the thermal, electrical, and structural analyses which led to that optimized design, and compares the computed RTPV performance to that of a Radioisotope Thermoelectric Generator (RTG) designed for the same mission. RTPVs are of course much less mature than RTGs, but our results indicate that—when fully developed—they could result in a 60% reduction of the heat source's mass, cost, and fuel loading, a 50% reduction of generator mass, a tripling of the power system's specific power, and a quadrupling of its efficiency. The paper concludes by briefly summarizing the RTPV's current technology status and assessing its potential applicability for the PFF mission. For other power systems (e.g., RTGs), demonstrating their flight readiness for a long mission is a very time-consuming process to determine the long-term effect of temperature-induced degradation mechanisms. But for the case of the described RTPV design, the paper lists a number of factors, primarily its cold (0 to 10 °C) converter temperature, that may greatly reduce the need for long-term tests to demonstrate generator lifetime. In any event, our analytical results suggest that the RTPV generator, when developed by DOE and/or NASA, would be quite valuable not only for the Pluto mission but also for other future missions requiring small, long-lived, low-mass generators.

Age-related decline in white matter integrity in a mouse model of tauopathy: an in vivo diffusion tensor magnetic resonance imaging study

PubMed Central

Sahara, Naruhiko; Perez, Pablo D.; Lin, Wen-Lang; Dickson, Dennis W.; Ren, Yan; Zeng, Huadong; Lewis, Jada; Febo, Marcelo

2016-01-01

Elevated expression of human hyperphosphorylated tau is associated with neuronal loss and white matter (WM) pathology in Alzheimer’s disease (AD) and related neurodegenerative disorders. Using in vivo diffusion tensor magnetic resonance imaging (DT-MRI) at 11.1 Tesla we measured age-related alterations in WM diffusion anisotropy indices in a mouse model of human tauopathy (rTg4510) and nontransgenic (nonTg) control mice at the age of 2.5, 4.5, and 8 months. Similar to previous DT-MRI studies in AD subjects, 8-month-old rTg4510 mice showed lower fractional anisotropy (FA) values in WM structures than nonTg. The low WM FA in rTg4510 mice was observed in the genu and splenium of the corpus callosum, anterior commissure, fimbria, and internal capsule and was associated with a higher radial diffusivity than nonTg. Interestingly, rTg4510 mice showed lower estimates for the mode of anisotropy than controls at 2.5 months suggesting that changes in this diffusivity metric are detectable at an early stage preceding severe tauopathy. Immunogold electron microscopy partly supports our diffusion tensor imaging findings. At the age of 4 months, rTg4510 mice show axonal tau inclusions and unmyelinated processes. At later ages (12 months and 14 months) we observed inclusions in myelin sheath, axons, and unmyelinated processes, and a “disorganized” pattern of myelinated fiber arrangement with enlarged inter-axonal spaces in rTg4510 but not in nonTg mice. Our data support a role for the progression of tau pathology in reduced WM integrity measured by DT-MRI. Further in vivo DT-MRI studies in the rTg4510 mouse should help better discern the detailed mechanisms of reduced FA and anisotropy mode, and the specific role of tau during neurodegeneration. PMID:24411290

GPHS-RTG's in support of the Cassini mission

NASA Astrophysics Data System (ADS)

1993-10-01

The following tasks were reported: Spacecraft integration and liaison; engineering support; safety; qualified unicouple fabrication; ETG fabrication/assembly/test; ground support equipment; RTG shipping and launch support; designs/reviews/mission applications; and project management/quality assurance/contract changes.

KSC-2011-6745

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- The multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission is position behind mobile plexiglass radiation shields in the high bay of the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida. The MMRTG was returned to the RTGF following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The generator will remain in the RTGF until is moved to the pad for integration on the rover. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

Requirements and Designs for Mars Rover RTGs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schock, Alfred; Shirbacheh, M; Sankarankandath, V

The current-generation RTGs (both GPHS and MOD) are designed for operation in a vacuum environment. The multifoil thermal insulation used in those RTGs only functions well in a good vacuum. Current RTGs are designed to operate with an inert cover gas before launch, and to be vented to space vacuum after launch. Both RTGs are sealed with a large number of metallic C-rings. Those seals are adequate for retaining the inert-gas overpressure during short-term launch operations, but would not be adequate to prevent intrusion of the Martian atmospheric gases during long-term operations there. Therefore, for the Mars Rover application, thosemore » RTGs just be modified to prevent the buildup of significant pressures of Mars atmosphere or of helium (from alpha decay of the fuel). In addition, a Mars Rover RTG needs to withstand a long-term dynamic environment that is much more severe than that seen by an RTG on an orbiting spacecraft or on a stationary planetary lander. This paper describes a typical Rover mission, its requirements, the environment it imposes on the RTG, and a design approach for making the RTG operable in such an environment. Specific RTG designs for various thermoelectric element alternatives are presented.; Reference CID #9268 and CID #9276.« less

Mitochondrial Energy and Redox Signaling in Plants

PubMed Central

Schwarzländer, Markus

2013-01-01

Abstract Significance: For a plant to grow and develop, energy and appropriate building blocks are a fundamental requirement. Mitochondrial respiration is a vital source for both. The delicate redox processes that make up respiration are affected by the plant's changing environment. Therefore, mitochondrial regulation is critically important to maintain cellular homeostasis. This involves sensing signals from changes in mitochondrial physiology, transducing this information, and mounting tailored responses, by either adjusting mitochondrial and cellular functions directly or reprogramming gene expression. Recent Advances: Retrograde (RTG) signaling, by which mitochondrial signals control nuclear gene expression, has been a field of very active research in recent years. Nevertheless, no mitochondrial RTG-signaling pathway is yet understood in plants. This review summarizes recent advances toward elucidating redox processes and other bioenergetic factors as a part of RTG signaling of plant mitochondria. Critical Issues: Novel insights into mitochondrial physiology and redox-regulation provide a framework of upstream signaling. On the other end, downstream responses to modified mitochondrial function have become available, including transcriptomic data and mitochondrial phenotypes, revealing processes in the plant that are under mitochondrial control. Future Directions: Drawing parallels to chloroplast signaling and mitochondrial signaling in animal systems allows to bridge gaps in the current understanding and to deduce promising directions for future research. It is proposed that targeted usage of new technical approaches, such as quantitative in vivo imaging, will provide novel leverage to the dissection of plant mitochondrial signaling. Antioxid. Redox Signal. 18, 2122–2144. PMID:23234467

KSC-2011-6674

NASA Image and Video Library

2011-07-12

CAPE CANAVERAL, Fla. -- Outside the RTG storage facility at NASA's Kennedy Space Center in Florida, the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission, enclosed in the protective mesh container, known as the "gorilla cage," is positioned inside the MMRTG trailer that will transport it to the Payload Hazardous Servicing Facility (PHSF). The cage protects the MMRTG and allows any excess heat generated to dissipate into the air. In the PHSF, the MMRTG temporarily will be installed on the MSL rover, Curiosity, for a fit check but will be installed on the rover for launch at the pad. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Curiosity, MSL's car-sized rover, has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is planned for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Cory Huston

KSC-2011-6738

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- A crane is positioned over the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission in the high bay of the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida. Preparations are under way to lift the mesh container, known as the "gorilla cage," from the support base on which the MMRTG is resting. The cage protects the MMRTG during transport and allows any excess heat generated to dissipate into the air. The MMRTG is returning to the RTGF following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6737

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- Department of Energy workers position mobile plexiglass radiation shields around the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission upon its arrival in the high bay of the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida. The shields are designed to minimize the employees' radiation exposure. The MMRTG is enclosed in a mesh container, known as the "gorilla cage," which protects it during transport and allows any excess heat generated to dissipate into the air. The MMRTG is returning to the RTGF following a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6719

NASA Image and Video Library

2011-07-13

CAPE CANAVERAL, Fla. -- In the airlock of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, Department of Energy employees lower the mesh container, known as the "gorilla cage," toward the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission. The mobile plexiglass radiation shields in the foreground help minimize the employees' radiation exposure. The cage protects the MMRTG during transport and allows any excess heat generated to dissipate into the air. Transport of the MMRTG to the RTG storage facility follows the completion of the MMRTG fit check on the Curiosity rover. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Kim Shiflett

KSC-2011-6741

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida, Department of Energy workers guide the mesh container enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission as it is lifted by a crane. The container, known as the "gorilla cage," protects the MMRTG during transport and allows any excess heat generated to dissipate into the air. The cage is being removed from around the MMRTG following it return to the RTGF from a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6673

NASA Image and Video Library

2011-07-12

CAPE CANAVERAL, Fla. -- Outside the RTG storage facility at NASA's Kennedy Space Center in Florida, a forklift positions the protective mesh container, known as the "gorilla cage," enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission inside the MMRTG trailer that will transport it to the Payload Hazardous Servicing Facility (PHSF). The cage protects the MMRTG and allows any excess heat generated to dissipate into the air. In the PHSF, the MMRTG temporarily will be installed on the MSL rover, Curiosity, for a fit check but will be installed on the rover for launch at the pad. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Curiosity, MSL's car-sized rover, has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is planned for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Cory Huston

KSC-2011-6739

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida, Department of Energy workers attach a crane to the mesh container enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission. The container, known as the "gorilla cage," protects it during transport and allows any excess heat generated to dissipate into the air. The cage is being removed from around the MMRTG following it return to the RTGF from a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6720

NASA Image and Video Library

2011-07-13

CAPE CANAVERAL, Fla. -- In the airlock of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, a Department of Energy employee positions the mesh container, known as the "gorilla cage," on the support base of the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission. The mobile plexiglass radiation shields, in the foreground at right, helps minimize the employees' radiation exposure. The cage protects the MMRTG during transport and allows any excess heat generated to dissipate into the air. Transport of the MMRTG to the RTG storage facility follows the completion of the MMRTG fit check on the Curiosity rover. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Kim Shiflett

KSC-2011-6676

NASA Image and Video Library

2011-07-12

CAPE CANAVERAL, Fla. -- Outside the RTG storage facility at NASA's Kennedy Space Center in Florida, the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission, enclosed in the protective mesh container known as the "gorilla cage," is strapped down inside the MMRTG trailer and ready for transport to the Payload Hazardous Servicing Facility (PHSF). The cage protects the MMRTG and allows any excess heat generated to dissipate into the air. In the PHSF, the MMRTG temporarily will be installed on the MSL rover, Curiosity, for a fit check but will be installed on the rover for launch at the pad. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Curiosity, MSL's car-sized rover, has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is planned for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Cory Huston

KSC-2011-6670

NASA Image and Video Library

2011-07-12

CAPE CANAVERAL, Fla. -- Outside the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, a forklift picks up the protective mesh container, known as the "gorilla cage," enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission for its move to the Payload Hazardous Servicing Facility (PHSF). The cage protects the MMRTG and allows any excess heat generated to dissipate into the air. In the PHSF, the MMRTG temporarily will be installed on the MSL rover, Curiosity, for a fit check but will be installed on the rover for launch at the pad. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Curiosity, MSL's car-sized rover, has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is planned for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Cory Huston

KSC-2011-6669

NASA Image and Video Library

2011-07-12

CAPE CANAVERAL, Fla. -- Department of Energy contractor employees roll the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission, enclosed in a protective mesh container known as the "gorilla cage," toward a forklift outside the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida for its move to the Payload Hazardous Servicing Facility (PHSF). The cage protects the MMRTG and allows any excess heat generated to dissipate into the air. In the PHSF, the MMRTG temporarily will be installed on the MSL rover, Curiosity, for a fit check but will be installed on the rover for launch at the pad. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Curiosity, MSL's car-sized rover, has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is planned for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Cory Huston

KSC-2011-6672

NASA Image and Video Library

2011-07-12

CAPE CANAVERAL, Fla. -- Outside the RTG storage facility at NASA's Kennedy Space Center in Florida, a forklift carries the protective mesh container, known as the "gorilla cage," enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission toward the MMRTG trailer that will transport it to the Payload Hazardous Servicing Facility (PHSF). The cage protects the MMRTG and allows any excess heat generated to dissipate into the air. In the PHSF, the MMRTG temporarily will be installed on the MSL rover, Curiosity, for a fit check but will be installed on the rover for launch at the pad. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Curiosity, MSL's car-sized rover, has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is planned for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Cory Huston

KSC-2011-6668

NASA Image and Video Library

2011-07-12

CAPE CANAVERAL, Fla. -- Department of Energy contractor employees roll the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission, enclosed in a protective mesh container known as the "gorilla cage," out of the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida for its move to the Payload Hazardous Servicing Facility (PHSF). The cage protects the MMRTG and allows any excess heat generated to dissipate into the air. In the PHSF, the MMRTG temporarily will be installed on the MSL rover, Curiosity, for a fit check but will be installed on the rover for launch at the pad. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Curiosity, MSL's car-sized rover, has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is planned for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Cory Huston

KSC-2011-6718

NASA Image and Video Library

2011-07-13

CAPE CANAVERAL, Fla. -- In the airlock of the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, Department of Energy employees lower the mesh container, known as the "gorilla cage," toward the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission. The employees are standing behind mobile plexiglass radiation shields to help minimize the employees' radiation exposure. The cage protects the MMRTG during transport and allows any excess heat generated to dissipate into the air. Transport of the MMRTG to the RTG storage facility follows the completion of the MMRTG fit check on the Curiosity rover. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Kim Shiflett

Radioisotopic energy conversion system (RECS): A new radioisotopic power cell, based on nuclear, atomic, and radiation transport principles

NASA Astrophysics Data System (ADS)

Steinfelds, Eric Victor

The topic of this thesis is the development of the Radioisotope Energy Conversion System (RECS) in a project which is utilizing analytical computational assisted design and some experimental Research in the investigation of fluorescers and effective transducers with the appropriate energy range choice for the conversion of energy. It is desirable to increase the efficiency in electrical power from the raw kinetic power available from the radioactive material within radioisotope power generators. A major step in this direction is the development and use of Radioisotope Energy Conversion Systems to supplement and ideally replace Radioactive Thermal Generators (RTG). It is possible to achieve electrical conversion efficiencies exceeding 25% for RECS power devices compared to only 9 percent efficiency for RTG's. The theoretical basis with existent materials for the potential achievability of efficiencies above 25% is documented within this thesis. The fundamental RECS consists of a radioisotope radiative source (C1), a mediating fluorescent gas (C2) which readily absorbs energy from the beta particles (or alpha's) and subsequently emits blue or UV photons, photovoltaic cells (C3) to convert the blue and UV photons into electrical energy [2], and electrical circuitry (C4). Solid State inspired component (C3), due to its theoretical (and attainable) high efficiency, is a large step ahead of the RTG design concept. The radioisotope flux source produces the beta(-) particles or alpha particles. Geometrically, presently, we prefer to have the ambient fluorescent gas surround the radioisotope flux source. Our fluorescer shall be a gas such as Krypton. Our specifically wide band-gap photovoltaic cells shall have gap energies which are slightly less than that of UV photons produced by the fluorescing gas. Diamond and Aluminum Nitride sample materials are good potential choices for photovoltaic cells, as is explained here in. Out of the material examples discussed, the highest electric power to mass ratio is found to be readily attainable with strontium-90 as the radiative source. Krypton-85 is indisputably the most efficient in RECS devices. In the conclusion in chapter VI, suggestions are given on acceptable ways of containing krypton-85 and providing sufficient shielding on deep space probes destined to use krypton-85 powered 'batteries'.

In vivo axonal transport deficits in a mouse model of fronto-temporal dementia

PubMed Central

Majid, Tabassum; Ali, Yousuf O.; Venkitaramani, Deepa V.; Jang, Ming-Kuei; Lu, Hui-Chen; Pautler, Robia G.

2014-01-01

Background Axonal transport is vital for neurons and deficits in this process have been previously reported in a few mouse models of Alzheimer's disease prior to the appearance of plaques and tangles. However, it remains to be determined whether axonal transport is defective prior to the onset of neurodegeneration. The rTg4510 mouse, a fronto-temporal dementia and parkinsonism-17 (FTDP-17) tauopathy model, over-express tau-P301L mutation found in familial forms of FTDP-17, in the forebrain driven by the calcium–calmodulin kinase II promoter. This mouse model exhibits tau pathology, neurodegeneration in the forebrain, and associated behavioral deficits beginning at 4–5 months of age. Animal model rTg4510 transgenic mice were used in these studies. Mice were given 2 μL of MnCl2 in each nostril 1 h prior to Magnetic Resonance Imaging (MRI). Following MnCl2 nasal lavage, mice were imaged using Manganese enhanced Magnetic Resonance Imaging (MEMRI) Protocol with TE = 8.5 ms, TR = 504 ms, FOV = 3.0 cm, matrix size = 128 × 128 × 128, number of cycles = 15 with each cycle taking approximately 2 min, 9 s, and 24 ms using Paravision software (BrukerBioSpin, Billerica, MA). During imaging, body temperature was maintained at 37.0 °C using an animal heating system (SA Instruments, Stony Brook, NY). Data analysis Resulting images were analyzed using Paravision software. Regions of interest (ROI) within the olfactory neuronal layer (ONL) and the water phantom consisting of one pixel (ONL) and 9 pixels (water) were selected and copied across each of the 15 cycles. Signal intensities (SI) of ONL and water phantom ROIs were measured. SI values obtained for ONL were then normalized the water phantom SI values. The correlation between normalized signal intensity in the ONL and time were assessed using Prism (GraphPad Software, San Diego, CA). Results Using the MEMRI technique on 1.5, 3, 5, and 10-month old rTg4510 mice and littermate controls, we found significant axonal transport deficits present in the rTg4510 mice beginning at 3 months of age in an age-dependent manner. Using linear regression analysis, we measured rates of axonal transport at 1.5, 3, 5, and 10 months of age in rTg4510 and WT mice. Axonal transport rates were observed in rTg4510 mice at 48% of WT levels at 3 months, 40% of WT levels at 5 months, and 30% of WT levels at 10 months of age. In order to determine the point at which tau appears in the cortex, we probed for phosphorylated tau levels, and found that pSer262 is present at 3 months of age, not earlier at 1.5 months of age, but observed no pathological tau species until 6 months of age, months after the onset of the transport deficits. In addition, we saw localization of tau in the ONL at 6 months of age. Discussion In our study, we identified the presence of age-dependent axonal transport deficits beginning at 3 months of age in rTg4510 mice. We correlated these deficits at 3 months to the presence of hyperphosphorylated tau in the brain and the presence within the olfactory epithelium. We observed tau pathology not only in the soma of these neurons but also within the axons and processes of these neurons. Our characterization of axonal transport in this tauopathy model provides a functional time point that can be used for future therapeutic interventions. PMID:24936422

In vivo axonal transport deficits in a mouse model of fronto-temporal dementia.

PubMed

Majid, Tabassum; Ali, Yousuf O; Venkitaramani, Deepa V; Jang, Ming-Kuei; Lu, Hui-Chen; Pautler, Robia G

2014-01-01

Axonal transport is vital for neurons and deficits in this process have been previously reported in a few mouse models of Alzheimer's disease prior to the appearance of plaques and tangles. However, it remains to be determined whether axonal transport is defective prior to the onset of neurodegeneration. The rTg4510 mouse, a fronto-temporal dementia and parkinsonism-17 (FTDP-17) tauopathy model, over-express tau-P301L mutation found in familial forms of FTDP-17, in the forebrain driven by the calcium-calmodulin kinase II promoter. This mouse model exhibits tau pathology, neurodegeneration in the forebrain, and associated behavioral deficits beginning at 4-5 months of age. rTg4510 transgenic mice were used in these studies. Mice were given 2 μL of MnCl2 in each nostril 1 h prior to Magnetic Resonance Imaging (MRI). Following MnCl2 nasal lavage, mice were imaged using Manganese enhanced Magnetic Resonance Imaging (MEMRI) Protocol with TE = 8.5 ms, TR = 504 ms, FOV = 3.0 cm, matrix size = 128 × 128 × 128, number of cycles = 15 with each cycle taking approximately 2 min, 9 s, and 24 ms using Paravision software (BrukerBioSpin, Billerica, MA). During imaging, body temperature was maintained at 37.0 °C using an animal heating system (SA Instruments, Stony Brook, NY). Resulting images were analyzed using Paravision software. Regions of interest (ROI) within the olfactory neuronal layer (ONL) and the water phantom consisting of one pixel (ONL) and 9 pixels (water) were selected and copied across each of the 15 cycles. Signal intensities (SI) of ONL and water phantom ROIs were measured. SI values obtained for ONL were then normalized the water phantom SI values. The correlation between normalized signal intensity in the ONL and time were assessed using Prism (GraphPad Software, San Diego, CA). Using the MEMRI technique on 1.5, 3, 5, and 10-month old rTg4510 mice and littermate controls, we found significant axonal transport deficits present in the rTg4510 mice beginning at 3 months of age in an age-dependent manner. Using linear regression analysis, we measured rates of axonal transport at 1.5, 3, 5, and 10 months of age in rTg4510 and WT mice. Axonal transport rates were observed in rTg4510 mice at 48% of WT levels at 3 months, 40% of WT levels at 5 months, and 30% of WT levels at 10 months of age. In order to determine the point at which tau appears in the cortex, we probed for phosphorylated tau levels, and found that pSer262 is present at 3 months of age, not earlier at 1.5 months of age, but observed no pathological tau species until 6 months of age, months after the onset of the transport deficits. In addition, we saw localization of tau in the ONL at 6 months of age. In our study, we identified the presence of age-dependent axonal transport deficits beginning at 3 months of age in rTg4510 mice. We correlated these deficits at 3 months to the presence of hyperphosphorylated tau in the brain and the presence within the olfactory epithelium. We observed tau pathology not only in the soma of these neurons but also within the axons and processes of these neurons. Our characterization of axonal transport in this tauopathy model provides a functional time point that can be used for future therapeutic interventions.

Retigabine, a Kv7.2/Kv7.3-Channel Opener, Attenuates Drug-Induced Seizures in Knock-In Mice Harboring Kcnq2 Mutations.

PubMed

Ihara, Yukiko; Tomonoh, Yuko; Deshimaru, Masanobu; Zhang, Bo; Uchida, Taku; Ishii, Atsushi; Hirose, Shinichi

2016-01-01

The hetero-tetrameric voltage-gated potassium channel Kv7.2/Kv7.3, which is encoded by KCNQ2 and KCNQ3, plays an important role in limiting network excitability in the neonatal brain. Kv7.2/Kv7.3 dysfunction resulting from KCNQ2 mutations predominantly causes self-limited or benign epilepsy in neonates, but also causes early onset epileptic encephalopathy. Retigabine (RTG), a Kv7.2/ Kv7.3-channel opener, seems to be a rational antiepileptic drug for epilepsies caused by KCNQ2 mutations. We therefore evaluated the effects of RTG on seizures in two strains of knock-in mice harboring different Kcnq2 mutations, in comparison to the effects of phenobarbital (PB), which is the first-line antiepileptic drug for seizures in neonates. The subjects were heterozygous knock-in mice (Kcnq2Y284C/+ and Kcnq2A306T/+) bearing the Y284C or A306T Kcnq2 mutation, respectively, and their wild-type (WT) littermates, at 63-100 days of age. Seizures induced by intraperitoneal injection of kainic acid (KA, 12mg/kg) were recorded using a video-electroencephalography (EEG) monitoring system. Effects of RTG on KA-induced seizures of both strains of knock-in mice were assessed using seizure scores from a modified Racine's scale and compared with those of PB. The number and total duration of spike bursts on EEG and behaviors monitored by video recording were also used to evaluate the effects of RTG and PB. Both Kcnq2Y284C/+ and Kcnq2A306T/+ mice showed significantly more KA-induced seizures than WT mice. RTG significantly attenuated KA-induced seizure activities in both Kcnq2Y284C/+ and Kcnq2A306T/+ mice, and more markedly than PB. This is the first reported evidence of RTG ameliorating KA-induced seizures in knock-in mice bearing mutations of Kcnq2, with more marked effects than those observed with PB. RTG or other Kv7.2-channel openers may be considered as first-line antiepileptic treatments for epilepsies resulting from KCNQ2 mutations.

Underwater magnetic gradiometer for magnetic anomaly detection, localization, and tracking

NASA Astrophysics Data System (ADS)

Kumar, S.; Sulzberger, G.; Bono, J.; Skvoretz, D.; Allen, G. I.; Clem, T. R.; Ebbert, M.; Bennett, S. L.; Ostrom, R. K.; Tzouris, A.

2007-04-01

GE Security and the Naval Surface Warfare Center, Panama City (NSWC-PC) have collaborated to develop a magnetic gradiometer, called the Real-time Tracking Gradiometer or RTG that is mounted inside an unmanned underwater vehicle (UUV). The RTG is part of a buried mine hunting platform being developed by the United States Navy. The RTG has been successfully used to make test runs on mine-like targets buried off the coast of Florida. We will present a general description of the system and latest results describing system performance. This system can be also potentially used for other applications including those in the area of Homeland Security.

Thermal Analysis of Step 2 GPHS for Next Generation Radioisotope Power Source Missions

NASA Astrophysics Data System (ADS)

Pantano, David R.; Hill, Dennis H.

2005-02-01

The Step 2 General Purpose Heat Source (GPHS) is a slightly larger and more robust version of the heritage GPHS modules flown on previous Radioisotope Thermoelectric Generator (RTG) missions like Galileo, Ulysses, and Cassini. The Step 2 GPHS is to be used in future small radioisotope power sources, such as the Stirling Radioisotope Generator (SRG110) and the Multi-Mission Radioisotope Thermoelectric Generator (MMRTG). New features include an additional central web of Fine Weave Pierced Fabric (FWPF) graphite in the aeroshell between the two Graphite Impact Shells (GIS) to improve accidental reentry and impact survivability and an additional 0.1-inch of thickness to the aeroshell broad faces to improve ablation protection. This paper details the creation of the thermal model using Thermal Desktop and AutoCAD interfaces and provides comparisons of the model to results of previous thermal analysis models of the heritage GPHS. The results of the analysis show an anticipated decrease in total thermal gradient from the aeroshell to the iridium clads compared to the heritage results. In addition, the Step 2 thermal model is investigated under typical SRG110 boundary conditions, with cover gas and gravity environments included where applicable, to provide preliminary guidance for design of the generator. Results show that the temperatures of the components inside the GPHS remain within accepted design limits during all envisioned mission phases.

Influence of society for academic emergency medicine grant mechanisms on postaward academic productivity.

PubMed

Safdar, Basmah; Paradise, Summer A; McMillian, Melissa; Holmes, James F

2015-02-01

The Society for Academic Emergency Medicine (SAEM) provides research training grants, but the future productivity of award recipients and nonrecipients is unclear. The study objective was to assess the association of the two SAEM research training mechanisms with scholarly productivity and rates of subsequent funding between nonrecipients and recipients. A secondary goal was to evaluate the productivity metrics for fellows trained at the Institutional Research Training Grant (IRTG) programs. The authors surveyed all 2002 through 2011 Research Training Grant (RTG; n = 64) and Institutional Research Training Grant (IRTG; n = 38) applicants. RTG outcomes were federal funding as a principal investigator (PI) or co-PI using National Institutes of Health RePORTER and scholarly productivity using PubMed. IRTG outcomes were SAEM-approved research fellowships and National Heart, Lung and Blood Institute K12 training awards. Sites applying for or receiving the IRTG multiple times were only counted once. Relative risks (RRs) with 95% confidence intervals (CIs) were calculated. Over 10 years, nine of 64 (14%) RTG and 10 of 38 (26%) IRTG applications were funded (two sites received multiple awards). Federal funding was obtained by seven of nine (78%) RTG recipients and 22 of 55 (40%) RTG nonrecipients (RR = 1.94, 95% CI = 1.21 to 3.13). All nine (100%, 95% CI = 72% to 100%) of RTG recipients had at least one manuscript, compared to 48 of the 55 (87%, 95% CI = 76% to 95%) nonrecipients. All nine (100%, 95% CI = 72% to 100%) RTG recipients remained in academics versus 44 of 55 (80%, 95% CI = 67% to 90%) nonrecipients. For the IRTG, four of seven awardees (57%, 95% CI = 18% to 90%) versus 0 of the 16 (0%, 95% CI = 0 to 17%) nonrecipients received National Heart, Lung and Blood Institute K12 awards (RR = 19.1, 95% CI = 1.16 to 314.0). Additionally, five of seven (71%, 95% CI = 29% to 96%) institutions became SAEM-approved fellowships compared to one of 16 (6%, 95% CI = 0 to 30%) nonrecipients (RR = 11.4, 95% CI = 1.61 to 80.7). SAEM RTG recipients were more likely to obtain federal funding postaward than nonrecipients. IRTG recipients were more likely to develop successful research training programs than nonrecipients. © 2015 by the Society for Academic Emergency Medicine.

[Cultivation of a permanent fish cell line in serum-free media special experiences with a cytotoxicity test for waste water samples

PubMed

Kohlpoth, Martin; Rusche, Brigitte

1997-01-01

The use of fetal calf serum (FCS) as standard medium additive for the cell cultivation must be regarded critically from the point of view of animal welfare as well as for scientific reasons and makes it necessary to look for alternatives. In the last years an in vitro cytotoxicity assay for the testing of industrial waste waters with the permanent fish cell line RTG-2 was established and pre-validated as an alternative to the fish test with the golden orfe. The application of FCS is also a special problem with regard to the testing of waste waters in a cytotoxicity test so that FCS-alternatives were tested. The RTG-2 cells were successfully adapted to the two solvents Basal Medium Supplement (BMS) and Ultroser-G (U-G) that are used to replace serum. The characterisation of these adapted cell lines showed no significant differences in growth rate, adhesion rate, viability and sensitivity to chemicals in comparison to the original RTG-2 cells. On the determination of the cytotoxicity of industrial waste waters the RTG-2 cells adapted to the BMS medium indicated a clearly higher toxicity of the waste water samples than the original RTG-2 cells. This result confirms the thesis that serum components react with waste water elements and thus change the bio-availability of toxic compounds.

Modular Radioisotope Thermoelectric Generator (RTG) Program. Final technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-12-31

Section 2.0 of this report summarizes the MOD-RTG reference flight design, and Section 3.0 discusses the Ground Demonstration System design. Multicouple technology development is discussed in Section 4.0, and Section 5.0 lists all published technical papers prepared during the course of the contract.

Management of Heat and Cold Stress -- Guidance to NATO Medical Personnel (Gestion des contraintes thermiques (chaleur et froid) Conseils aux personnels medicaux de I’OTAN)

DTIC Science & Technology

2013-12-01

de la performance de leurs troupes; b) d’importants écarts scientifiques / de capacités existent en ce qui concerne la susceptibilité, le... La HFM/RTG-187 avait pour but de : a) comparer et évaluer les ressources techniques qui sont actuellement utilisées pour un « système de gestion des ...d’une doctrine et de programmes d’enseignement intégrés pour la gestion des risques thermiques afin de garantir le maintien

Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology.

PubMed

Song, Lixin; Lu, Sherry X; Ouyang, Xuesong; Melchor, Jerry; Lee, Julie; Terracina, Giuseppe; Wang, Xiaohai; Hyde, Lynn; Hess, J Fred; Parker, Eric M; Zhang, Lili

2015-03-26

Microtubule associated protein tau is the major component of the neurofibrillary tangles (NFTs) found in the brains of patients with Alzheimer's disease and several other neurodegenerative diseases. Tau mutations are associated with frontotemperal dementia with parkinsonism on chromosome 17 (FTDP-17). rTg4510 mice overexpress human tau carrying the P301L FTDP-17 mutation and develop robust NFT-like pathology at 4-5 months of age. The current study is aimed at characterizing the rTg4510 mice to better understand the genesis of tau pathology and to better enable the use of this model in drug discovery efforts targeting tau pathology. Using a panel of immunoassays, we analyzed the age-dependent formation of pathological tau in rTg4510 mice and our data revealed a steady age-dependent accumulation of pathological tau in the insoluble fraction of brain homogenates. The pathological tau was associated with multiple post-translational modifications including aggregation, phosphorylation at a wide variety of sites, acetylation, ubiquitination and nitration. The change of most tau species reached statistical significance at the age of 16 weeks. There was a strong correlation between the different post-translationally modified tau species in this heterogeneous pool of pathological tau. Total tau in the cerebrospinal fluid (CSF) displayed a multiphasic temporal profile distinct from the steady accumulation of pathological tau in the brain. Female rTg4510 mice displayed significantly more aggressive accumulation of pathological tau in the brain and elevation of total tau in CSF than their male littermates. The immunoassays described here were used to generate the most comprehensive description of the changes in various tau species across the lifespan of the rTg4510 mouse model. The data indicate that development of tauopathy in rTg4510 mice involves the accumulation of a pool of pathological tau that carries multiple post-translational modifications, a process that can be detected well before the histological detection of NFTs. Therapeutic treatment targeting tau should therefore aim to reduce all tau species associated with the pathological tau pool rather than reduce specific post-translational modifications. There is still much to learn about CSF tau in physiological and pathological processes in order to use it as a translational biomarker in drug discovery.

Logistical concepts associated with international shipments using the USA/9904/B(U)F RTG Transportation System (RTGTS)

NASA Astrophysics Data System (ADS)

Barklay, Chadwick D.; Miller, Roger G.; Pugh, Barry K.; Howell, Edwin I.

1997-01-01

Over the last 30 years, radioisotopes have provided heat from which electrical power is generated. For space missions, the isotope of choice has generally been 238PuO2, its long half-life making it ideal for supplying power to remote satellites and spacecraft like the Voyager, Pioneer, and Viking missions, as well as the recently launched Galileo and Ulysses missions, and the presently planned Cassini mission. Electric power for future space missions will be provided by either radioisotopic thermoelectric generators (RTG), radioisotope thermophotovoltaic systems (RTPV), alkali metal thermal to electrical conversion (AMTEC) systems, radioisotope Stirling systems, or a combination of these. The type of electrical power system has yet to be specified for the ``Pluto Express'' mission. However, the current plan does incorporate the use of Russian launch platforms for the spacecraft. The implied tasks associated with this plan require obtaining international certification for the transport of the radioisotopic power system, and resolving any logistical issues associated with the actual shipment of the selected radioisotopic power system. This paper presents a conceptual summary of the logistical considerations associated with shipping the selected radioisotopic power system using the USA/9904/B(U)F-85, Radioisotope Thermoelectric Generator Transportation System (RTGTS).

Restricted growth of U-type infectious haematopoietic necrosis virus (IHNV) in rainbow trout cells may be linked to casein kinase II activity

USGS Publications Warehouse

Park, J.-W.; Moon, C.H.; Harmache, A.; Wargo, A.R.; Purcell, M.K.; Bremont, M.; Kurath, G.

2011-01-01

Previously, we demonstrated that a representative M genogroup type strain of infectious haematopoietic necrosis virus (IHNV) from rainbow trout grows well in rainbow trout-derived RTG-2 cells, but a U genogroup type strain from sockeye salmon has restricted growth, associated with reduced genome replication and mRNA transcription. Here, we analysed further the mechanisms for this growth restriction of U-type IHNV in RTG-2 cells, using strategies that assessed differences in viral genes, host immune regulation and phosphorylation. To determine whether the viral glycoprotein (G) or non-virion (NV) protein was responsible for the growth restriction, four recombinant IHNV viruses were generated in which the G gene of an infectious IHNV clone was replaced by the G gene of U- or M-type IHNV and the NV gene was replaced by NV of U- or M-type IHNV. There was no significant difference in the growth of these recombinants in RTG-2 cells, indicating that G and NV proteins are not major factors responsible for the differential growth of the U- and M-type strains. Poly I:C pretreatment of RTG-2 cells suppressed the growth of both U- and M-type IHNV, although the M virus continued to replicate at a reduced level. Both viruses induced type 1 interferon (IFN1) and the IFN1 stimulated gene Mx1, but the expression levels in M-infected cells were significantly higher than in U-infected cells and an inhibitor of the IFN1-inducible protein kinase PKR, 2-aminopurine (2-AP), did not affect the growth of U- or M-type IHNV in RTG-2 cells. These data did not indicate a role for the IFN1 system in the restricted growth of U-type IHNV in RTG-2 cells. Prediction of kinase-specific phosphorylation sites in the viral phosphoprotein (P) using the NetPhosK program revealed differences between U- and M-type P genes at five phosphorylation sites. Pretreatment of RTG-2 cells with a PKC inhibitor or a p38MAPK inhibitor did not affect the growth of the U- and M-type viruses. However, 100 μm of the casein kinase II (CKII) inhibitor, 5,6-dichloro-1-β-d-ribofuranosylbenzimidazole (DRB), reduced the titre of the U type 8.3-fold at 24 h post-infection. In contrast, 100 μm of the CKII inhibitor reduced the titre of the M type only 1.3-fold at 48 h post-infection. Our data suggest that the different growth of U- and M-type IHNV in RTG-2 cells may be linked to a differential requirement for cellular protein kinases such as CKII for their growth.

Power System for Venus Surface Exploration

NASA Technical Reports Server (NTRS)

Landis, Geoffrey A.; Mellott, Kenneth

2002-01-01

A radioisotope power and cooling system is designed to provide electrical power for a probe operating on the surface of Venus. Most foreseeable electronics devices and sensors cannot operate at the 450 C ambient surface temperature of Venus. Because the mission duration is substantially long and the use of thermal mass to maintain an operable temperature range is likely impractical, some type of active refrigeration may be required to keep electronic components at a temperature below ambient. The fundamental cooling parameters are the cold sink temperature, the hot sink temperature, and the amount of heat to be removed. In this instance, it is anticipated that electronics would have a nominal operating temperature of 300 C. Due to the highly thermal convective nature of the high-density (90 bar CO2) atmosphere, the hot sink temperature was assumed to be 50 C, which provided a 500 C temperature of the cooler's heat rejecter to the ambient atmosphere. The majority of the heat load on the cooler is from the high temperature ambient surface environment on Venus, with a small contribution of heat generation from electronics and sensors. Both thermoelectric (RTG) and dynamic power conversion systems were analyzed, based on use of a standard isotope (General-purpose heat source, or GPHS) brick. For the radioisotope Stirling power converter configuration designed, the Sage model predicts a thermodynamic power output capacity of 478.1 watts, which slightly exceeds the required 469.1 watts. The hot sink temperature is 1200 C, and the cold sink temperature is 500 C. The required heat input is 1740 watts. This gives a thermodynamic efficiency of 27.48 %. It is estimated that the mechanical efficiency of the power converter design is on the order of 85 %, based on experimental measurements taken from 500-watt power class, laboratory-tested Stirling engines. The overall efficiency is calculated to be 23.36 %. The mass of the power converter is estimated at approximately 21.6 kg. Additional information is included in the original extended abstract.

Applicability of STEM-RTG and High-Power SRG Power Systems to the Discovery and Scout Mission Capabilities Expansion (DSMCE) Study of ASRG-Based Missions

NASA Technical Reports Server (NTRS)

Colozza, Anthony J.; Cataldo, Robert L.

2015-01-01

This study looks at the applicability of utilizing the Segmented Thermoelectric Modular Radioisotope Thermoelectric Generator (STEM-RTG) or a high-power radioisotope generator to replace the Advanced Stirling Radioisotope Generator (ASRG), which had been identified as the baseline power system for a number of planetary exploration mission studies. Nine different Discovery-Class missions were examined to determine the applicability of either the STEM-RTG or the high-power SRG power systems in replacing the ASRG. The nine missions covered exploration across the solar system and included orbiting spacecraft, landers and rovers. Based on the evaluation a ranking of the applicability of each alternate power system to the proposed missions was made.

KSC-2011-6742

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida, the mesh container enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission is lifted from around the MMRTG. The container, known as the "gorilla cage," protects the MMRTG during transport and allows any excess heat generated to dissipate into the air. The cage is being removed following the return of the MMRTG to the RTGF from a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The workers at right are observing the operation from behind a mobile plexiglass radiation shield to minimize their radiation exposure. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

KSC-2011-6671

NASA Image and Video Library

2011-07-12

CAPE CANAVERAL, Fla. -- Outside the RTG storage facility at NASA's Kennedy Space Center in Florida, a plexiglass shield has been installed on the forklift enlisted to move the protective mesh container, known as the "gorilla cage," enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission. The shield minimizes the amount of debris dispersed by the wheels of the forklift that can contact the gorilla cage. The cage protects the MMRTG and allows any excess heat generated to dissipate into the air. The MMRTG is being moved to the Payload Hazardous Servicing Facility (PHSF) where it temporarily will be installed on the MSL rover, Curiosity, for a fit check but will be installed on the rover for launch at the pad. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Curiosity, MSL's car-sized rover, has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is planned for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Cory Huston

KSC-2011-6740

NASA Image and Video Library

2011-07-14

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility (RTGF) at NASA's Kennedy Space Center in Florida, Department of Energy workers guide the mesh container enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission as it is lifted by a crane. The container, known as the "gorilla cage," protects the MMRTG during transport and allows any excess heat generated to dissipate into the air. The cage is being removed from around the MMRTG following it return to the RTGF from a fit check on MSL's Curiosity rover in the Payload Hazardous Servicing Facility (PHSF). The workers at right are observing the operation from behind a mobile plexiglass radiation shield to minimize their radiation exposure. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for signs of life, including methane, and help determine if the gas is from a biological or geological source. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. Launch of MSL aboard a United Launch Alliance Atlas V rocket is targeted for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Troy Cryder

Fluorine-19 magnetic resonance imaging probe for the detection of tau pathology in female rTg4510 mice.

PubMed

Yanagisawa, Daijiro; Ibrahim, Nor Faeizah; Taguchi, Hiroyasu; Morikawa, Shigehiro; Kato, Tomoko; Hirao, Koichi; Shirai, Nobuaki; Sogabe, Takayuki; Tooyama, Ikuo

2018-05-01

Aggregation of tau into neurofibrillary tangles (NFTs) is characteristic of tauopathies, including Alzheimer's disease. Recent advances in tau imaging have attracted much attention because of its potential contributions to early diagnosis and monitoring of disease progress. Fluorine-19 magnetic resonance imaging ( 19 F-MRI) may be extremely useful for tau imaging once a high-quality probe has been formulated. In this investigation, a novel fluorine-19-labeling compound has been developed as a probe for tau imaging using 19 F-MRI. This compound is a buta-1,3-diene derivative with a polyethylene glycol side chain bearing a CF 3 group and is known as Shiga-X35. Female rTg4510 mice (a mouse model of tauopathy) and wild-type mice were intravenously injected with Shiga-X35, and magnetic resonance imaging of each mouse's head was conducted in a 7.0-T horizontal-bore magnetic resonance scanner. The 19 F-MRI in rTg4510 mice showed an intense signal in the forebrain region. Analysis of the signal intensity in the forebrain region revealed a significant accumulation of fluorine-19 magnetic resonance signal in the rTg4510 mice compared with the wild-type mice. Histological analysis showed fluorescent signals of Shiga-X35 binding to the NFTs in the brain sections of rTg4510 mice. Data collected as part of this investigation indicate that 19 F-MRI using Shiga-X35 could be a promising tool to evaluate tau pathology in the brain. © 2017 Wiley Periodicals, Inc.

SNAP 19 Viking Program. Bimonthly technical progress report, October 1979-November 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1979-12-01

Monitoring and evaluation of Viking 1 Lander power system data continued. The RTG series power range as measured at the PCDA was 65 to 68 watts at fin root temperatures between 280/sup 0/F and 310/sup 0/F. The Mars landed performance history of Viking 1 include both the minimum and maximum data for each of the SOL days. Monitoring and evaluation of Viking 2 Lander power system data continued. The RTG series power range as measured at the PCDA was 71 to 72 watts at fin root temperatures between 230/sup 0/F and 260/sup 0/F. The Mars landed performance history of Vikingmore » 2 include both the minimum and maximum data for each of the SOL days. The performance of both power systems continues to be very satisfactory. Power system performance data for Pioneer 10 and Pioneer 11 spacecraft were monitored through the reporting period. The estimated RTG system net power was 116 watts for Pioneer 10 and 118 watts for Pioneer Saturn. The September 1 encounter with Saturn appears to have had no deleterious effect on the RTG's of the spacecraft power system. The telemetry signals from both spacecrafts remain satisfactory.« less

Termination of aquired and natural immunological tolerance with specific complexes

PubMed Central

1975-01-01

It was possible to terminate the induced unresponsive state to bovine serum albumin (BSA) and the natural unresponsive state to autologous thyroglobulin in rabbits (RTg) by immunization with complexes composed of heterologous cross-reacting antibody and the tolerated antigens. The unresponsive state was terminated in rabbits made unresponsive by neonatal injections of BSA and then 3 mo later injected with complexes composed of BSA and guinea pig antihuman serum albumin. This termination was manifested by the presence of anti-BSA plaque-forming cells. Similarly, the natural unresponsive state was terminated in adult rabbits injected with complexes between RTg and guinea pig antibovine thyroglobulin (BTg) in that thyroid lesions and circulating anti-RTg were produced. The results can be best explained by the presence of unresponsive T cells and competent B cells, where the guinea pig gamma globulin (antibody) activates T cells specific for the guinea pig gamma globulin portion of the complexes and thus permits stimulation of B cells competent to the exposed determinants of the tolerated (BSA or RTg) portion of the complexes. The detailed mechanism for the activation of B cells in tolerant animals is discussed. PMID:1095680

KSC-97PC1068

NASA Image and Video Library

1997-07-18

Jet Propulsion Laboratory (JPL) workers Dan Maynard and John Shuping prepare to install a radioisotope thermoelectric generator (RTG) on the Cassini spacecraft in the Payload Hazardous Servicing Facility (PHSF). The three RTGs which will provide electrical power to Cassini on its mission to the Saturnian system are undergoing mechanical and electrical verification testing in the PHSF. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate far from the Sun where solar power systems are not feasible. The Cassini mission is scheduled for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed for NASA by JPL

Space Science

NASA Image and Video Library

1997-07-18

Jet Propulsion Research Lab (JPL) workers use a borescope to verify the pressure relief device bellow's integrity on a radioisotope thermoelectric generator (RTG) that has been installed on the Cassini spacecraft in the Payload Hazardous Servicing Facility. The activity is part of the mechanical and electrical verification testing of RTGs during prelaunch processing. RTGs use heat from the natural decay of plutonium to generate electrical power. The three RTGs on Cassini will enable the spacecraft to operate far from the Sun where solar power systems are not feasible. They will provide electrical power to Cassini on it seven year trip to the Saturnian system and during its four year mission at Saturn.

Reach-to-grasp movement as a minimization process.

PubMed

Yang, Fang; Feldman, Anatol G

2010-02-01

It is known that hand transport and grasping are functionally different but spatially coordinated components of reach-to-grasp (RTG) movements. As an extension of this notion, we suggested that body segments involved in RTG movements are controlled as a coherent ensemble by a global minimization process associated with the necessity for the hand to reach the motor goal. Different RTG components emerge following this process without pre-programming. Specifically, the minimization process may result from the tendency of neuromuscular elements to diminish the spatial gap between the actual arm-hand configuration and its virtual (referent) configuration specified by the brain. The referent configuration is specified depending on the object shape, localization, and orientation. Since the minimization process is gradual, it can be interrupted and resumed following mechanical perturbations, at any phase during RTG movements, including hand closure. To test this prediction of the minimization hypothesis, we asked subjects to reach and grasp a cube placed within the reach of the arm. Vision was prevented during movement until the hand returned to its initial position. As predicted, by arresting wrist motion at different points of hand transport in randomly selected trials, it was possible to halt changes in hand aperture at any phase, not only during hand opening but also during hand closure. Aperture changes resumed soon after the wrist was released. Another test of the minimization hypothesis was made in RTG movements to an object placed beyond the reach of the arm. It has previously been shown (Rossi et al. in J Physiol 538:659-671, 2002) that in such movements, the trunk motion begins to contribute to hand transport only after a critical phase when the shifts in the referent arm configuration have finished (at about the time when hand velocity is maximal). The minimization rule suggests that when the virtual contribution of the arm to hand transport is completed, guidance of hand aperture switches from the arm to the trunk control system. As a consequence, hand aperture changes can be halted by trunk arrests but only if they are prolonged beyond a critical phase. As predicted, hand transport and hand aperture in RTG movements beyond the reach of the arm were halted by trunk arrests only if they were prolonged beyond the time of peak hand velocity. Hand motion and aperture changes resumed only when the trunk was released. While supporting the minimization hypothesis, our findings imply that not only spatial but also temporal characteristics of each component, including the shortest, hand closure component of RTG movements, are controlled in a flexible, task-specific way.

Comparative studies of saxitoxin (STX) -induced cytotoxicity in Neuro-2a and RTG-2 cell lines: An explanation with respect to changes in ROS.

PubMed

Zhou, Zhongyuan; Tang, Xuexi; Chen, Hongmei; Wang, You

2018-02-01

Saxitoxin (STX), a paralytic shellfish toxin (PST) produced from toxic bloom-forming dinoflagellates, was selected to comparatively investigate the induction of cytotoxicity and apoptosis and a possible mechanism based on changes in the antioxidant defence system of two cellular strains: the mouse neuroblastoma cell line Neuro-2a and the rainbow trout fish cell line RTG-2. Increasing concentrations of STX (0-256 nM) presented little cytotoxic or apoptotic effects on the two cell lines. Measurements of cellular viability, lethal ratio and LDH leakage showed slight changes in Neuro-2a and RTG-2 cells (p > 0.05), and similar results were observed for cellular morphology and apoptotic rates. The contents of the main reactive oxygen species (ROS) components, superoxide anion (O 2 - ) and hydrogen peroxide (H 2 O 2 ), were markedly increased in Neuro-2a cell with STX exposure at middle (15 nM) and high (150 nM) concentrations (p < 0.05), and the simultaneous increase of the ratio of reduced/oxidized glutathione (GSH/GSSG) (p < 0.05) inferred the occurrence of oxidative stress. However, little difference was observed in all treated groups of RTG-2 cells. The activities of three antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT) and glutathione reductase (GR), were significantly enhanced in Neuro-2a cells in the middle and high concentration groups (p < 0.05), while glutathione peroxidase (GPX) obviously decreased (p < 0.05) in all treated groups. Little change was found in RTG-2 cells with the same exposures. These results provided evidence that STX exposure altered the redox status of Neuro-2a cells and resulted in oxidative stress, but the same exposure exerted little effect on RTG-2 cells. Therefore, Neuro-2a cells are more sensitive than reproductive cells to STX exposure, and the antioxidant systems appears to be partly responsible for this differentiation response. Copyright © 2017 Elsevier Ltd. All rights reserved.

Cassini RTG acceptance test results and RTG performance on Galileo and Ulysses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kelly, C.E.; Klee, P.M.

Flight acceptance testing has been completed for the RTGs to be used on the Cassini spacecraft which is scheduled for an October 6, 1997 launch to Saturn. The acceptance test program includes vibration tests, magnetic field measurements, mass properties (weight and c.g.) and thermal vacuum test. This paper presents the thermal vacuum test results. Three RTGs are to be used, F-2, F-6, and F-7. F-5 is the backup RTG, as it was for the Galileo and Ulysses missions launched in 1989 and 1990, respectively. RTG performance measured during the thermal vacuum tests carried out at the Mound Laboratory facility metmore » all specification requirements. Beginning of mission (BOM) and end of mission (EOM) power predictions have been made based on these tests results. BOM power is predicted to be 888 watts compared to the minimum requirement of 826 watts. Degradation models predict the EOM power after 16 years is to be 640 watts compared to a minimum requirement of 596 watts. Results of small scale module tests are also shown. The modules contain couples from the qualification and flight production runs. The tests have exceeded 28,000 hours (3.2 years) and are continuing to provide increased confidence in the predicted long term performance of the Cassini RTGs. All test results indicate that the power requirements of the Cassini spacecraft will be met. BOM and EOM power margins of over 5% are predicted. Power output from telemetry for the two Galileo RTGs are shown from the 1989 launch to the recent Jupiter encounter. Comparisons of predicted, measured and required performance are shown. Telemetry data are also shown for the RTG on the Ulysses spacecraft which completed its planned mission in 1995 and is now in the extended mission.« less

Cassini RTG acceptance test results and RTG performance on Galileo and Ulysses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kelly, C.E.; Klee, P.M.

Flight acceptance testing has been completed for the RTGs to be used on the Cassini spacecraft which is scheduled for an October 6, 1997 launch to Saturn. The acceptance test program includes vibration tests, magnetic field measurements, properties (weight and c.g.) and thermal vacuum test. This paper presents The thermal vacuum test results. Three RTGs are to be used, F-2, F-6, and F-7. F-5 is tile back-up RTG, as it was for the Galileo and Ulysses missions launched in 1989 and 1990, respectively. RTG performance measured during the thermal vacuum tests carried out at die Mound Laboratory facility met allmore » specification requirements. Beginning of mission (BOM) and end of mission (EOM) power predictions have been made based on than tests results. BOM power is predicted to be 888 watts compared to the minimum requirement of 826 watts. Degradation models predict the EOM power after 16 years is to be 640 watts compared to a minimum requirement of 596 watts. Results of small scale module tests are also showing. The modules contain couples from the qualification and flight production runs. The tests have exceeded 28,000 hours (3.2 years) and are continuing to provide increased confidence in the predicted long term performance of the Cassini RTGs. All test results indicate that the power requirements of the Cassini spacecraft will be met. BOM and EOM power margins of over five percent are predicted. Power output from telemetry for the two Galileo RTGs are shown from the 1989 launch to the recent Jupiter encounter. Comparisons of predicted, measured and required performance are shown. Telemetry data are also shown for the RTG on the Ulysses spacecraft which completed its planned mission in 1995 and is now in the extended mission.« less

Cassini RTG Acceptance Test Results and RTG Performance on Galileo and Ulysses

DOE R&D Accomplishments Database

Kelly, C. E.; Klee, P. M.

1997-06-01

Flight acceptance testing has been completed for the RTGs to be used on the Cassini spacecraft which is scheduled for an October 6, 1997 launch to Saturn. The acceptance test program includes vibration tests, magnetic field measurements, properties (weight and c.g.) and thermal vacuum test. This paper presents The thermal vacuum test results. Three RTGs are to be used, F 2, F 6, and F 7. F 5 is tile back up RTG, as it was for the Galileo and Ulysses missions launched in 1989 and 1990, respectively. RTG performance measured during the thermal vacuum tests carried out at die Mound Laboratory facility met all specification requirements. Beginning of mission (BOM) and end of mission (EOM) power predictions have been made based on than tests results. BOM power is predicted to be 888 watts compared to the minimum requirement of 826 watts. Degradation models predict the EOM power after 16 years is to be 640 watts compared to a minimum requirement of 596 watts. Results of small scale module tests are also showing. The modules contain couples from the qualification and flight production runs. The tests have exceeded 28,000 hours (3.2 years) and are continuing to provide increased confidence in the predicted long term performance of the Cassini RTGs. All test results indicate that the power requirements of the Cassini spacecraft will be met. BOM and EOM power margins of over five percent are predicted. Power output from telemetry for the two Galileo RTGs are shown from the 1989 launch to the recent Jupiter encounter. Comparisons of predicted, measured and required performance are shown. Telemetry data are also shown for the RTG on the Ulysses spacecraft which completed its planned mission in 1995 and is now in the extended mission.

Underwater (UW) Unexploded Ordnance (UXO) Multi-Sensor Data Base (MSDB) Collection

DTIC Science & Technology

2009-07-01

11 FIGURE 6 RTG SENSOR. FOUR SENSOR TRIADS ARE SHOWN, EACH WITH A 3-AXIS FLUXGATE MAGNETOMETER ...used by RTG to measure the gradients. Each triad includes a 3-axis fluxgate magnetometer and a set of feedback coils. The outputs of three triad...each with a 3-axis fluxgate magnetometer (internal, not clearly visible) and a set of 3 feedback coils. The upper triad 3-axis magnetometer

SCO-1, a Novel Plasmid-Mediated Class A β-Lactamase with Carbenicillinase Characteristics from Escherichia coli▿

PubMed Central

Papagiannitsis, C. C.; Loli, A.; Tzouvelekis, L. S.; Tzelepi, E.; Arlet, G.; Miriagou, V.

2007-01-01

A novel class A β-lactamase (SCO-1) encoded by an 80-kb self-transferable plasmid from Escherichia coli is described. The interaction of SCO-1 with β-lactams was similar to that of the CARB-type enzymes. Also, SCO-1 exhibited a 51% amino acid sequence identity with the RTG subgroup of chromosomal carbenicillinases (RTG-1, CARB-5, and CARB-8). PMID:17353248

Adavanced RTG and thermoelectric materials study

NASA Technical Reports Server (NTRS)

Eggers, P. E.

1971-01-01

A comprehensive, generalized two-dimensional RTG analysis computer program was developed. This program is capable of analyzing any specified RTG design under a wide range of transient as well as steady-state operating conditions. The feasibility of a new concept for the design of segmented (or single-phase) thermoelectric couples was demonstrated. A SiGe-PbTe segmented couple involving pressure contacted junctions at the intermediate- and hot-junction temperatures was successfully encapsulated in a hermetically sealed bellows enclosure. This bellows-encapsulated couple was operated between a hot- and cold-junction temperature of 1200 K and 450 K, respectively, with a measured energy conversion efficiency of 7.6 + or - .5 per cent. An experimental study of selected sublimation barrier schemes revealed that a significant reduction in the sublimation rate of p-type PbTe could be achieved by using multiple layers of SiO2 fibers. A comparison of the barrier effectiveness is given for three different barrier designs.

The CRAF/Cassini power subsystem - Preliminary design update

NASA Technical Reports Server (NTRS)

Atkins, Kenneth L.; Brisendine, Philip; Clark, Karla; Klein, John; Smith, Richard

1991-01-01

A chronology is provided of the rationale leading from the early Mariner spacecraft to the CRAF/Cassini Mariner Mark II power subsystem architecture. The display pathway began with a hybrid including a solar photovoltaic array, a radioisotope thermoelectric generator (RTG), and a battery supplying a power profile with a peak loading of about 300 W. The initial concept was to distribute power through a new solid-state, programmable switch controlled by an embedded microprocessor. As the overall mission, science, and project design matured, the power requirements increased. The design evolved from the hybrid to two RTG plus batteries to meet peak loadings of near 500 W in 1989. Later that year, circumstances led to abandonment of the distributed computer concept and a return to centralized control. Finally, as power requirements continued to grow, a third RTG was added to the design and the battery removed, with the return to the discharge-controller for transients during fault recovery procedures.

Visual imaging control systems of the Mariner to Jupiter and Saturn spacecraft

NASA Technical Reports Server (NTRS)

Larks, L.

1979-01-01

Design and fabrication of optical systems for the Mariner Jupiter Saturn (Voyager) mission is described. Because of the long distances of these planets from the sun, the spacecraft was designed without solar panels with the electricity generated on-board by radio-isotope thermal generators (RTG). The presence of RTG's and Jupiter radiation environment required that the optical systems be fabricated out of radiation stabilized materials. A narrow angle and a wide angle camera are located on the spacecraft scan platform, with the narrow angle lens a modification of the Mariner 10 lens. The optical system is described, noting that the lens was modified by moving the aperture correctors forward and placing a spider mounted secondary mirror in the original back surface of the second aperture corrector. The wide angle lens was made out of cerium doped, radiation stabilized optical glass with greatest blue transmittance, which would be resistant to RTG and Jupiter radiation.

KSC-97PC1066

NASA Image and Video Library

1997-07-18

Jet Propulsion Laboratory (JPL) engineers examine the interface surface on the Cassini spacecraft prior to installation of the third radioisotope thermoelectric generator (RTG). The other two RTGs, at left, already are installed on Cassini. The three RTGs will be used to power Cassini on its mission to the Saturnian system. They are undergoing mechanical and electrical verification testing in the Payload Hazardous Servicing Facility. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate far from the Sun where solar power systems are not feasible. The Cassini mission is scheduled for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed for NASA by JPL

KSC-97PC1090

NASA Image and Video Library

1997-07-19

Workers in the Payload Hazardous Servicing Facility remove the storage collar from a radioisotope thermoelectric generator (RTG) in preparation for installation on the Cassini spacecraft. Cassini will be outfitted with three RTGs. The power units are undergoing mechanical and electrical verification tests in the PHSF. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate at great distances from the Sun where solar power systems are not feasible. The Cassini mission is targeted for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle

Stratified Shear Flows In Pipe Geometries

NASA Astrophysics Data System (ADS)

Harabin, George; Camassa, Roberto; McLaughlin, Richard; UNC Joint Fluids Lab Team Team

2015-11-01

Exact and series solutions to the full Navier-Stokes equations coupled to the advection diffusion equation are investigated in tilted three-dimensional pipe geometries. Analytic techniques for studying the three-dimensional problem provide a means for tackling interesting questions such as the optimal domain for mass transport, and provide new avenues for experimental investigation of diffusion driven flows. Both static and time dependent solutions will be discussed. NSF RTG DMS-0943851, NSF RTG ARC-1025523, NSF DMS-1009750.

Long term behavior of silicon germanium thermoelectric generators

NASA Technical Reports Server (NTRS)

Shields, V.

1981-01-01

Results of tests of the long term performance of SiGe radioisotope thermoelectric generators (RTG) are presented. Three modules were monitored for 17,000-32,300 hr at hot junction temperatures of 1,085, 1,055, and 1,000 C; coating the unicouples with a 12,000 A thick layer of Si3N4 protected the modules from Si sublimation. Output degraded less than 0.3-0.4%/1,000 hr over the testing period. Life tests on a multihundredwatt (MHW) SiGe generator with 312 couples at a hot shoe temperature of 1,040 C dealt with power of 150 W at 30 V, with 0.5%/1,000 hr performance degradation. Si deposition on the insulation was found to enhance electrical conductance until a saturation point was reached. Disassembly of a test module after 16,750 hr revealed a Mo build-up, SiN4 coating deterioration, and Ti diffustion from the hot shoe to cooler regions of the junction. The presence of an Al2O3 insulator was recognized as preventing coating loss. Performance records from the Voyager and Les-8 satellites' RTG's are compared and show similar, 0.25%/1,000 hr degradation rates; RTG storage is judged to be feasible and the tests lead to projections of a 600,000 hr lifetime for a SiGe RTG.

The Science Behind 'The Martian' - Staying Warm on Mars

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wham, Bob; Ulrich, George

Set in the not-too-distant future, “The Martian” is the story of an astronaut stranded on Mars who has to rely on his own wit and ingenuity to survive the planet’s hostile conditions. If Mark Watney’s mission were real, Oak Ridge National Laboratory would be playing a vital role in his survival, as it would be the sole source of the Plutonium-238 needed for the RTG, as well as the fuel’s containment material in the form of iridium clad vent sets.

Comparison of In Vivo and Ex Vivo MRI for the Detection of Structural Abnormalities in a Mouse Model of Tauopathy

PubMed Central

Holmes, Holly E.; Powell, Nick M.; Ma, Da; Ismail, Ozama; Harrison, Ian F.; Wells, Jack A.; Colgan, Niall; O'Callaghan, James M.; Johnson, Ross A.; Murray, Tracey K.; Ahmed, Zeshan; Heggenes, Morten; Fisher, Alice; Cardoso, M. Jorge; Modat, Marc; O'Neill, Michael J.; Collins, Emily C.; Fisher, Elizabeth M. C.; Ourselin, Sébastien; Lythgoe, Mark F.

2017-01-01

With increasingly large numbers of mouse models of human disease dedicated to MRI studies, compromises between in vivo and ex vivo MRI must be fully understood in order to inform the choice of imaging methodology. We investigate the application of high resolution in vivo and ex vivo MRI, in combination with tensor-based morphometry (TBM), to uncover morphological differences in the rTg4510 mouse model of tauopathy. The rTg4510 mouse also offers a novel paradigm by which the overexpression of mutant tau can be regulated by the administration of doxycycline, providing us with a platform on which to investigate more subtle alterations in morphology with morphometry. Both in vivo and ex vivo MRI allowed the detection of widespread bilateral patterns of atrophy in the rTg4510 mouse brain relative to wild-type controls. Regions of volume loss aligned with neuronal loss and pathological tau accumulation demonstrated by immunohistochemistry. When we sought to investigate more subtle structural alterations in the rTg4510 mice relative to a subset of doxycycline-treated rTg4510 mice, ex vivo imaging enabled the detection of more regions of morphological brain changes. The disadvantages of ex vivo MRI may however mitigate this increase in sensitivity: we observed a 10% global shrinkage in brain volume of the post-mortem tissues due to formalin fixation, which was most notable in the cerebellum and olfactory bulbs. However, many central brain regions were not adversely affected by the fixation protocol, perhaps due to our “in-skull” preparation. The disparity between our TBM findings from in vivo and ex vivo MRI underlines the importance of appropriate study design, given the trade-off between these two imaging approaches. We support the utility of in vivo MRI for morphological phenotyping of mouse models of disease; however, for subtler phenotypes, ex vivo offers enhanced sensitivity to discrete morphological changes. PMID:28408879

Comparison of In Vivo and Ex Vivo MRI for the Detection of Structural Abnormalities in a Mouse Model of Tauopathy.

PubMed

Holmes, Holly E; Powell, Nick M; Ma, Da; Ismail, Ozama; Harrison, Ian F; Wells, Jack A; Colgan, Niall; O'Callaghan, James M; Johnson, Ross A; Murray, Tracey K; Ahmed, Zeshan; Heggenes, Morten; Fisher, Alice; Cardoso, M Jorge; Modat, Marc; O'Neill, Michael J; Collins, Emily C; Fisher, Elizabeth M C; Ourselin, Sébastien; Lythgoe, Mark F

2017-01-01

With increasingly large numbers of mouse models of human disease dedicated to MRI studies, compromises between in vivo and ex vivo MRI must be fully understood in order to inform the choice of imaging methodology. We investigate the application of high resolution in vivo and ex vivo MRI, in combination with tensor-based morphometry (TBM), to uncover morphological differences in the rTg4510 mouse model of tauopathy. The rTg4510 mouse also offers a novel paradigm by which the overexpression of mutant tau can be regulated by the administration of doxycycline, providing us with a platform on which to investigate more subtle alterations in morphology with morphometry. Both in vivo and ex vivo MRI allowed the detection of widespread bilateral patterns of atrophy in the rTg4510 mouse brain relative to wild-type controls. Regions of volume loss aligned with neuronal loss and pathological tau accumulation demonstrated by immunohistochemistry. When we sought to investigate more subtle structural alterations in the rTg4510 mice relative to a subset of doxycycline-treated rTg4510 mice, ex vivo imaging enabled the detection of more regions of morphological brain changes. The disadvantages of ex vivo MRI may however mitigate this increase in sensitivity: we observed a 10% global shrinkage in brain volume of the post-mortem tissues due to formalin fixation, which was most notable in the cerebellum and olfactory bulbs. However, many central brain regions were not adversely affected by the fixation protocol, perhaps due to our "in-skull" preparation. The disparity between our TBM findings from in vivo and ex vivo MRI underlines the importance of appropriate study design, given the trade-off between these two imaging approaches. We support the utility of in vivo MRI for morphological phenotyping of mouse models of disease; however, for subtler phenotypes, ex vivo offers enhanced sensitivity to discrete morphological changes.

Mars Science Laboratory Rover Integrated Pump Assembly Bellows Jamming Failure

NASA Technical Reports Server (NTRS)

Johnson, Michael R.; Johnson, Joel; Birur, Gajanana; Bhandari, Pradeep; Karlmann, Paul

2012-01-01

The Mars Science Laboratory rover and spacecraft utilize two mechanically pumped fluid loops for heat transfer to and from the internal electronics assemblies and the Radioisotope Thermo-Electric Generator (RTG). The heat transfer fluid is Freon R-11 (CFC-11) which has a large coefficient of thermal expansion. The Freon within the heat transfer system must have a volume for safe expansion of the fluid as the system temperature rises. The device used for this function is a gas-over-liquid accumulator. The accumulator uses a metal bellows to separate the fluid and gas sections. During expansion and contraction of the fluid in the system, the bellows extends and retracts to provide the needed volume change. During final testing of a spare unit, the bellows would not extend the full distance required to provide the needed expansion volume. Increasing the fluid pressure did not loosen the jammed bellows either. No amount of stroking the bellows back and forth would get it to pass the jamming point. This type of failure, if it occurred during flight, would result in significant overpressure of the heat transfer system leading to a burst failure at some point in the system piping. A loss of the Freon fluid would soon result in a loss of the mission. The determination of the source of the jamming of the bellows was quite elusive, leading to an extensive series of tests and analyses. The testing and analyses did indicate the root cause of the failure, qualitatively. The results did not provide a set of dimensional limits for the existing hardware design that would guarantee proper operation of the accumulator. In the end, a new design was developed that relied on good engineering judgment combined with the test results to select a reliable enough solution that still met other physical constraints of the hardware, the schedule, and the rover system.

Test and evaluation of the Navy half-watt RTG. [Radioisotope Thermoelectric Generator

NASA Technical Reports Server (NTRS)

Rosell, F. E., Jr.; Lane, S. D.; Eggers, P. E.; Gawthrop, W. E.; Rouklove, P. G.; Truscello, V. C.

1976-01-01

The radioisotope thermoelectric generator (RTG) considered is to provide a continuous minimum power output of 0.5 watt at 6.0 to 8.5 volts for a minimum period of 15 years. The mechanical-electrical evaluation phase discussed involved the conduction of shock and vibration tests. The thermochemical-physical evaluation phase consisted of an analysis of the materials and the development of a thermal model. The thermoelectric evaluation phase included the accelerated testing of the thermoelectric modules.

Integration of the real-time tracking gradiometer (RTG) aboard the autonomous underwater vehicle (AUV) Morpheus

NASA Astrophysics Data System (ADS)

Allen, George I.; Matthews, Robert; Wynn, Michael

2001-10-01

In keeping with the Navy's policy to remove humans from harms way, the Autonomous Underwater Vehicle (AUV) is replacing human divers for many missions. The Advanced Marine Systems Lab at Florida Atlantic University (FAU) has developed a small, magnetically friendly, modular plastic AUV called Morpheus designed for coastal applications and especially suited for very shallow water (VSW) mine reconnaissance. Currently employed sensor technologies on AUVs have certain deficiencies and limitations when used across the wide gamut of naval targets and environments, and a strong requirement exists for a sensor or sensors to fill these niches. The Real-time Tracking Gradiometer (RTG) selected for this integration is truly such a niche sensor because its capabilities are not degraded by media interfaces or environmental conditions. It is an experimental prototype fluxgate magnetometer array developed by Quantum Magnetics for the Coastal Systems Station (CSS) and was designed to be man portable and self contained. While limited by physics in detection range, it is capable of detecting ferrous targets under the worst environmental conditions, even when the target is buried. While not having the range of sonar, the RTG does not respond to the false alarms that are indicated by sonar, and since it is capable of also providing range and bearing information, it provides an invaluable niche filling classification tool. The placing of any magnetic sensing system on a conventional AUV is a non-trivial problem. The standard AUV is designed around materials and components that were selected to maximize performance without regard to the magnetic properties of the materials used in its fabrication. To minimize the degradation of sensor performance caused by the platform, several steps must be taken. These include; the substitution of nonferrous components for ferrous, maximizing the separation between the sensor and magnetic field sources, minimizing current loops and using auxiliary current and field sensors capable of generating noise canceling signals. To maximize utility, the magnetic sensor systems should also provide range, bearing and magnetic target strength. While all data and results contained in this paper have been obtained with land-based testing, they are easily adapted to the underwater environment of the AUV. The RTG was recently attached to the Morpheus, and data collected with the unmodified Morpheus powered and undergoing simulated sea motion table. These tests indicate that integration, while not trivial, is indeed feasible, and work is continuing toward mounting the sensor internal to the AUV and implementing the required noise mitigation solutions.

SNAP 19 Viking Program. Bimonthly technical progress report, April-May 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-01-01

Monitoring and evaluation of Viking Lander 1 power system data continued. The RTG series power range as measured at the PCDA was 65 to 67 watts at finroot temperatures between 280/sup 0/F and 310/sup 0/F. The Mars Lander performance history of Viking 1 include both the minimum and maximum data for each of the SOL days. Final available power system data for Viking Lander 2 are shown. Typical SOL day cycles for mission day 1193 are presented. The RTG series power ranged from 69 to 70 watts at finroot temperatures between 270/sup 0/F and 300/sup 0/F. The Mars Lander performancemore » history for Viking 2 is shown. Power system performance data for Pioneer 10 and Pioneer Saturn (initially designated Pioneer 11) were monitored through the reporting period. After adjusting for the telemetry characteristics, the estimated RTG system net power was 114 watts for both Pioneer 10 and Pioneer Saturn.« less

Retrograde Signaling as a Mechanism of Yeast Adaptation to Unfavorable Factors.

PubMed

Trendeleva, T A; Zvyagilskaya, R A

2018-02-01

Mitochondria perform many essential functions in eukaryotic cells. Being the main producers of ATP and the site of many catabolic and anabolic reactions, they participate in intracellular signaling, proliferation, aging, and formation of reactive oxygen species. Mitochondrial dysfunction is the cause of many diseases and even cell death. The functioning of mitochondria in vivo is impossible without interaction with other cellular compartments. Mitochondrial retrograde signaling is a signaling pathway connecting mitochondria and the nucleus. The major signal transducers in the yeast retrograde response are Rtg1p, Rtg2p, and Rtg3p proteins, as well as four additional negative regulatory factors - Mks1p, Lst8p, and two 14-3-3 proteins (Bmh1/2p). In this review, we analyze current information on the retrograde signaling in yeast that is regarded as a stress or homeostatic response mechanism to changes in various metabolic and biosynthetic activities that occur upon mitochondrial dysfunction. We also discuss relations between retrograde signaling and other signaling pathways in the cell.

Apollo 12 Mission image - Modular Equipment Stowage Assemble (MESA) and the Fuel Cask on the Lunar Module (LM)

NASA Image and Video Library

1969-11-19

AS12-48-7034 (19 Nov. 1969) --- A close-up view of a portion of quadrant II of the descent stage of the Apollo 12 Lunar Module (LM), photographed during the Apollo 12 extravehicular activity (EVA). At lower left is the LM's Y footpad. The empty Radioisotope Thermoelectric Generator (RTG) fuel cask is at upper right. The fuel capsule has already been removed and placed in the RTG. The RTG furnishes power for the Apollo Lunar Surface Experiments Package (ALSEP) which the Apollo 12 astronauts deployed on the moon. The LM's descent engine skirt is in the center background. The rod-like object protruding out from under the footpad is a lunar surface sensing probe. Astronaut Richard F. Gordon Jr., command module pilot, remained with the Command and Service Modules (CSM) in lunar orbit while astronauts Charles Conrad Jr., commander; and Alan L. Bean, lunar module pilot, descended in the LM to explore the moon.

RTG performance on Galileo and Ulysses and Cassini test results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kelly, C. Edward; Klee, Paul M.

Power output from telemetry for the two Galileo RTGs are shown from the 1989 launch to the recent Jupiter encounter. Comparisons of predicted, measured and required performance are shown. Similar comparisons are made for the RTG on the Ulysses spacecraft which completed its planned mission in 1995. Also presented are test results from small scale thermoelectric modules and full scale converters performed for the Cassini program. The Cassini mission to Saturn is scheduled for an October 1997 launch. Small scale module test results on thermoelectric couples from the qualification and flight production runs are shown. These tests have exceeded 19,000more » hours are continuing to provide increased confidence in the predicted long term performance of the Cassini RTGs. Test results are presented for full scale units both ETGs (E-6, E-7) and RTGs (F-2, F-5) along with mission power predictions. F-5, fueled in 1985, served as a spare for the Galileo and Ulysses missions and plays the same role in the Cassini program. It has successfully completed all acceptance testing. The ten years storage between thermal vacuum tests is the longest ever experienced by an RTG. The data from this test are unique in providing the effects of long term low temperature storage on power output. All ETG and RTG test results to date indicate that the power requirements of the Cassini spacecraft will be met. BOM and EOM power margins of at least five percent are predicted.« less

Effects of structured testing versus routine testing of blood glucose in diabetes self-management: A randomized controlled trial.

PubMed

Nishimura, Akiko; Harashima, Shin-Ichi; Fujita, Yoshihito; Tanaka, Daisuke; Wang, Yu; Liu, Yanyan; Inagaki, Nobuya

2017-01-01

To compare the effects of structured and routine testing regimens used in self-monitoring of blood glucose (SMBG) on glycemic control and diabetes self-management in insulin-naïve type 2 diabetes patients. Sixty-two outpatients with insulin-naïve type 2 diabetes were randomly allocated into two less-frequent SMBG usage groups: a structured testing group (STG) and a routine testing group (RTG). Subjects in STG measured 7-points on SMBG for 3 consecutive days once every two months without daily testing; subjects in RTG measured SMBG 3 times each week before breakfast on Monday and Friday and before dinner on Wednesday. The primary endpoint was HbA1c reduction. The secondary endpoints were change in body weight, blood pressure, treatment change, and self-management performance change. HbA1c levels were significantly decreased by 0.32% (3.50mmol/mol) in STG, partly because physicians changed medications more actively. In contrast, body weight and systolic/diastolic blood pressure were significantly reduced by 0.94kg and 6.8/4.7mmHg, respectively, in RTG, possibly related to the increased diet and exercise score in RTG. Structured testing without daily testing is beneficial for glycemic control; routine testing 3 times a week is more helpful for daily self-management. In low SMBG frequency usage, these two regimens can be utilized according to individual diabetic conditions. Copyright © 2017 Elsevier Inc. All rights reserved.

Progressive Functional Impairments of Hippocampal Neurons in a Tauopathy Mouse Model

PubMed Central

Ciupek, Sarah M.; Cheng, Jingheng; Ali, Yousuf O.; Lu, Hui-Chen

2015-01-01

The age-dependent progression of tau pathology is a major characteristic of tauopathies, including Alzheimer's disease (AD), and plays an important role in the behavioral phenotypes of AD, including memory deficits. Despite extensive molecular and cellular studies on tau pathology, it remains to be determined how it alters the neural circuit functions underlying learning and memory in vivo. In rTg4510 mice, a Tau-P301L tauopathy model, hippocampal place fields that support spatial memories are abnormal at old age (7–9 months) when tau tangles and neurodegeneration are extensive. However, it is unclear how the abnormality in the hippocampal circuit function arises and progresses with the age-dependent progression of tau pathology. Here we show that in young (2–4 months of age) rTg4510 mice, place fields of hippocampal CA1 cells are largely normal, with only subtle differences from those of age-matched wild-type control mice. Second, high-frequency ripple oscillations of local field potentials in the hippocampal CA1 area are significantly reduced in young rTg4510 mice, and even further deteriorated in old rTg4510 mice. The ripple reduction is associated with less bursty firing and altered synchrony of CA1 cells. Together, the data indicate that deficits in ripples and neuronal synchronization occur before overt deficits in place fields in these mice. The results reveal a tau-pathology-induced progression of hippocampal functional changes in vivo. PMID:26019329

Cassini's RTGs undergo mechanical and electrical verification testing in the PHSF

NASA Technical Reports Server (NTRS)

1997-01-01

Jet Propulsion Laboratory (JPL) engineers examine the interface surface on the Cassini spacecraft prior to installation of the third radioisotope thermoelectric generator (RTG). The other two RTGs, at left, already are installed on Cassini. The three RTGs will be used to power Cassini on its mission to the Saturnian system. They are undergoing mechanical and electrical verification testing in the Payload Hazardous Servicing Facility. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate far from the Sun where solar power systems are not feasible. The Cassini mission is scheduled for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed for NASA by JPL.

KSC-97PC1067

NASA Image and Video Library

1997-07-18

This radioisotope thermoelectric generator (RTG), at center, will undergo mechanical and electrical verification testing now that it has been installed on the Cassini spacecraft in the Payload Hazardous Servicing Facility. A handling fixture, at far left, is still attached. Three RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate far from the Sun where solar power systems are not feasible. The Cassini mission is scheduled for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed for NASA by the Jet Propulsion Laboratory

Cassini's RTGs undergo mechanical and electrical verification tests in the PHSF

NASA Technical Reports Server (NTRS)

1997-01-01

Workers in the Payload Hazardous Servicing Facility remove the storage collar from a radioisotope thermoelectric generator (RTG) in preparation for installation on the Cassini spacecraft. Cassini will be outfitted with three RTGs. The power units are undergoing mechanical and electrical verification tests in the PHSF. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate at great distances from the Sun where solar power systems are not feasible. The Cassini mission is targeted for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle.

Selenide isotope generator for the Galileo mission. Reliability program plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1978-10-01

The reliability program plan for the Selenide Isotope Generator (SIG) program is presented. It delineates the specific tasks that will be accomplished by Teledyne Energy Systems and its suppliers during design, development, fabrication and test of deliverable Radioisotopic Thermoelectric Generators (RTG), Electrical Heated Thermoelectric Generators (ETG) and associated Ground Support Equipment (GSE). The Plan is formulated in general accordance with procedures specified in DOE Reliability Engineering Program Requirements Publication No. SNS-2, dated June 17, 1974. The Reliability Program Plan presented herein defines the total reliability effort without further reference to Government Specifications. The reliability tasks to be accomplished are delineatedmore » herein and become the basis for contract compliance to the extent specified in the SIG contract Statement of Work.« less

Induction of EROD and BFCOD activities in tissues of barbel (Barbus callensis) from a water reservoir in Algeria.

PubMed

Habila, Safia; Leghouchi, Essaid; Valdehita, Ana; Bermejo-Nogales, Azucena; Khelili, Smail; Navas, José M

2017-08-01

EROD and BFCOD activities were measured in liver and gills of barbel (Barbus callensis, a native North African species) captured at Beni Haroun lake, the most important water reservoir in Algeria. This lake receives wastewater from different origins. Thus, we assessed the level of pollution through the induction of detoxification activities in tissues of barbel, evaluating simultaneously the suitability of this species to be used as a sentinel. Fish were collected between March 2015 and January 2016 at three locations taking into account the pollution sources and accessibility. In liver, EROD and BFCOD showed the highest induction in October specially in the location of the dam that received pollutants. In gills, only EROD, but not BFCOD, activity was detected. Maximal EROD induction was noted in samples from January. Fish cell lines (RTG-2 and PLHC-1) were exposed to sediments extracts collected at Beni Haroun lake and enzyme activities (EROD and BFCOD, respectively) were measured. Sediment extracts did not induce BFCOD activity. The EROD induction observed in RTG-2 cells was in line with the results observed in fish tissues. Our results suggest that the lake is at risk from pollution and that Barbus callensis is a good sentinel species. Copyright © 2017 Elsevier Inc. All rights reserved.

RTG resource book for western states and provinces: Final proceedings

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The Western Interstate Energy Board held a workshop and liaison activities among western states, provinces, and utilities on the formation of Regional Transmission Groups (RTGs). Purpose of the activities was to examine the policy implications for western states and provinces in the formation of RTGs in the West, the implications for western ratepayers and utilities of the RTG formation and potential impacts of RTGs on the western electricity system. The workshop contributed to fulfilling the transmission access and competition objectives of Title VII of the Energy Policy Act of 1992.

The Science Behind 'The Martian' - Staying Warm on Mars

ScienceCinema

Wham, Bob; Ulrich, George

2018-06-21

Set in the not-too-distant future, “The Martian” is the story of an astronaut stranded on Mars who has to rely on his own wit and ingenuity to survive the planet’s hostile conditions. If Mark Watney’s mission were real, Oak Ridge National Laboratory would be playing a vital role in his survival, as it would be the sole source of the Plutonium-238 needed for the RTG, as well as the fuel’s containment material in the form of iridium clad vent sets.

Low Intensity Low Temperature (LILT) measurements and coefficients on new photovoltaic structures

NASA Technical Reports Server (NTRS)

Schelman, David A.; Jenkins, Philip P.; Brinker, David J.; Appelbaum, Joseph

1995-01-01

Past NASA missions to Mars, Jupiter, and the outer planets were powered by radioisotope thermal generators (RTG's). Although these devices proved to be reliable, their high cost and highly toxic radioactive heat source has made them far less desirable for future planetary missions. This has resulted in a renewed search for alternate energy sources, some of them being photovoltaic (PV) and thermophotovoltaic (TPV). Both of these alternate energy sources convert light/thermal energy directly into electricity. In order to create a viable PV and TPV data base for planetary mission planners and cell designers, we have compiled low temperature low intensity (LILT) I-V data on single junction and multi-junction high efficiency solar cells. The cells tested here represent the latest photovoltaic technology. Using this LILT data to calculate dI(sub SC)/dT, dV(sub OC)/dT, dFF/dT, and also as a function of intensity, an accurate prediction of cell performance under the AMO spectrum can be determined. When combined with QUantum efficiency at Low Temperature (QULT) data, one can further enhance the data by adding spectral variations to the measurements. This paper presents an overview of LILT measurements and is only intended to be used as a guideline for material selection and performance predictions. As single junction and multi-junction cell technologies emerge, new test data must be collected. Cell materials included are Si, GaAs/Ge, GainP/GaAs/Ge, InP, InGaAs/InP, InP/InGaAs/InP, and GainP. Temperatures range as low as -175 C and intensities range from 1 sun to .02 suns.

RTG performance on Galileo and Ulysses and Cassini test results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kelly, C.E.; Klee, P.M.

Power output from telemetry for the two Galileo RTGs are shown from the 1989 launch to the recent Jupiter encounter. Comparisons of predicted, measured and required performance are shown. Similar comparisons are made for the RTG on the Ulysses spacecraft which completed its planned mission in 1995. Also presented are test results from small scale thermoelectric modules and full scale converters performed for the Cassini program. The Cassini mission to Saturn is scheduled for an October 1997 launch. Small scale module test results on thermoelectric couples from the qualification and flight production runs are shown. These tests have exceeded 19,000more » hours are continuing to provide increased confidence in the predicted long term performance of the Cassini RTGs. Test results are presented for full scale units both ETGs (E-6, E-7) and RTGs (F-2, F-5) along with mission power predictions. F-5, fueled in 1985, served as a spare for the Galileo and Ulysses missions and plays the same role in the Cassini program. It has successfully completed all acceptance testing. The ten years storage between thermal vacuum tests is the longest ever experienced by an RTG. The data from this test are unique in providing the effects of long term low temperature storage on power output. All ETG and RTG test results to date indicate that the power requirements of the Cassini spacecraft will be met. BOM and EOM power margins of at least five percent are predicted. {copyright} {ital 1997 American Institute of Physics.}« less

Sustainable land management practices as providers of several ecosystem services under rainfed Mediterranean agroecosystems

NASA Astrophysics Data System (ADS)

Almagro, María; de Vente, Joris; Boix-Fayós, Carolina; García-Franco, Noelia; Melgares de Aguilar, Javier; González, David; Solé-Benet, Albert; Martínez-Mena, María

2015-04-01

Little is known about the multiple impacts of sustainable land management practices on soil and water conservation, carbon sequestration, mitigation of global warming, and crop yield productivity in semiarid Mediterranean agroecosystems. We hypothesized that a shift from intensive tillage to more conservative tillage management practices (reduced tillage optionally combined with green manure) leads to an improvement in soil structure and quality and will reduce soil erosion and enhance carbon sequestration in semiarid Mediterranean rainfed agroecosystems. To test the hypothesis, we assessed the effects of different tillage treatments (conventional (CT), reduced (RT), reduced tillage combined with green manure (RTG), and no tillage (NT)) on soil structure and soil water content, runoff and erosion control, soil CO2 emissions, crop yield and carbon sequestration in two semiarid agroecosystems with organic rainfed almond in the Murcia Region southeast Spain). It was found that reduction and suppression of tillage under almonds led to an increase in soil water content in both agroecosystems. Crop yields ranged from 775 to 1766 kg ha-1 between tillage 18 treatments, but we did not find a clear relation between soil water content and crop yield. RT and RTG treatments showed lower soil erosion rates and higher crop yields of almonds than under CT treatment. Overall, higher soil organic carbon contents and aggregate stability were observed under RTG treatment than under RT or CT treatment. It is concluded that conversion from CT to RTG is suitable to increase carbon inputs without enhancing soil CO2 emissions in semiarid Mediterranean agroecosystems.

Safety and tolerability of different titration rates of retigabine (ezogabine) in patients with partial-onset seizures.

PubMed

Biton, Victor; Gil-Nagel, Antonio; Brodie, Martin J; Derossett, Sarah E; Nohria, Virinder

2013-11-01

Retigabine (RTG; international nonproprietary name)/ezogabine (EZG; US adopted name) is an antiepileptic drug (AED) that prolongs neuronal voltage-gated potassium-channel KCNQ2-5 (Kv 7.2-7.5) opening. This double-blind study evaluated different RTG/EZG dose-titration rates. Patients (N=73) with partial-onset seizures receiving concomitant AEDs were randomized to one of three titration groups, all of which were initiated at RTG/EZG 300mg/day divided into three equal doses. Fast-, medium-, and slow-titration groups received dose increments of 150mg/day every 2, 4, and 7 days, respectively, achieving the target dose of 1200mg/day after 13, 25, and 43 days, respectively. Safety assessments were performed throughout. Discontinuation rates due to treatment-emergent adverse events (TEAEs) were numerically higher in the fast- (10/23) and medium- (7/22) titration groups than in the slow-titration group (3/23) but statistical significance was achieved only for the high-titration group compared with the low-titration group (p=0.024). Stratified analysis, with concomitant AEDs divided into enzyme inducers (carbamazepine, phenytoin, oxcarbazepine) or noninducers, showed that the risk of discontinuation due primarily to TEAEs was significantly higher in the fast- (p=0.010) but not in the medium-titration group (p=0.078) when compared with the slow-titration group. Overall, the slow-titration rate appeared to be best tolerated and was used in further efficacy and safety studies with RTG/EZG. Copyright © 2013 Elsevier B.V. All rights reserved.

Progressive Pathological Changes in Neurochemical Profile of the Hippocampus and Early Changes in the Olfactory Bulbs of Tau Transgenic Mice (rTg4510).

PubMed

Kim, Jieun; Choi, In-Young; Duff, Karen E; Lee, Phil

2017-06-01

Tauopathies such as Alzheimer's disease and frontotemporal lobe degeneration (FTLD-tau) dementia, characterized by pathologic aggregation of the microtubule-associated tau protein and formation of neurofibrillary tangles, have been linked to neurodegeneration and cognitive decline. The early detection of cerebral abnormalities and the identification of biological contributors to the continuous pathologic processes of neurodegeneration in tauopathies critically hinge on sensitive and reliable measures of biomarkers in the living brain. In this study, we measured alterations in a number of key neurochemicals associated with tauopathy-induced neurodegeneration in the hippocampus and the olfactory bulbs of a transgenic mouse model of FTLD-tauopathy, line rTg4510, using in vivo 1 H magnetic resonance spectroscopy at 9.4 T. The rTg4510 line develops tauopathy at a young age (4-5 months), reaching a severe stage by 8-12 months of age. Longitudinal measurement of neurochemical concentrations in the hippocampus of mice from 5 to 12 months of age showed significant progressive changes with distinctive disease staging patterns including N-acetylaspartate, myo-inositol, γ-aminobutyric acid, glutathione and glutamine. The accompanying hippocampal volume loss measured using magnetic resonance imaging showed significant correlation (p < 0.01) with neurochemical measurements. Neurochemical alterations in the olfactory bulbs were more pronounced than those in the hippocampus in rTg4510 mice. These results demonstrate progressive neuropathology in the mouse model and provide potential biomarkers of early neuropathological events and effective noninvasive monitoring of the disease progression and treatment efficacy, which can be easily translated to clinical studies.

Dopaminergic Modulation of Cortical Plasticity in Alzheimer's Disease Patients

PubMed Central

Koch, Giacomo; Di Lorenzo, Francesco; Bonnì, Sonia; Giacobbe, Viola; Bozzali, Marco; Caltagirone, Carlo; Martorana, Alessandro

2014-01-01

In animal models of Alzheimer's disease (AD), mechanisms of cortical plasticity such as long-term potentiation (LTP) and long-term depression (LTD) are impaired. In AD patients, LTP-like cortical plasticity is abolished, whereas LTD seems to be preserved. Dopaminergic transmission has been hypothesized as a new player in ruling mechanisms of cortical plasticity in AD. We aimed at investigating whether administration of the dopamine agonist rotigotine (RTG) could modulate cortical plasticity in AD patients, as measured by theta burst stimulation (TBS) protocols of repetitive transcranial stimulation applied over the primary motor cortex. Thirty mild AD patients were tested in three different groups before and after 4 weeks of treatment with RTG, rivastigmine (RVT), or placebo (PLC). Each patient was evaluated for plasticity induction of LTP/LTD-like effects using respectively intermittent TBS (iTBS) or continuous TBS protocols. Short-latency afferent inhibition (SAI) protocol was performed to indirectly assess central cholinergic activity. A group of age-matched healthy controls was recruited for baseline comparisons. Results showed that at baseline, AD patients were characterized by impaired LTP-like cortical plasticity, as assessed by iTBS. These reduced levels of LTP-like cortical plasticity were increased and normalized after RTG administration. No effect was induced by RVT or PLC on LTP. LTD-like cortical plasticity was not modulated in any condition. Cholinergic activity was increased by both RTG and RVT. Our findings reveal that dopamine agonists may restore the altered mechanisms of LTP-like cortical plasticity in AD patients, thus providing novel implications for therapies based on dopaminergic stimulation. PMID:24859851

GPHS-RTGs in support of the Cassini RTG Program

NASA Astrophysics Data System (ADS)

1995-04-01

The technical progress achieved during the period 26 Sep. 1994 - 2 Apr. 1995 on Contract DE-AC03-91SF-18852 Radioisotope Thermoelectric Generators and Ancillary Activities is described herein. Monthly technical activity for the period 27 Feb. - 2 Apr. 1995 is included in this progress report. The report addresses tasks, including: spacecraft integration and liaison; engineering support; safety; qualified unicouple production; ETG fabrication, assembly, and test; ground support equipment; RTG shipping and launch support; designs, reviews, and mission applications; project management, quality assurance, reliability, contract changes, CAGO acquisition (operating funds), and CAGO maintenance and repair; and CAGO acquisition (capital funds).

Mission applications for advanced photovoltaic solar arrays

NASA Technical Reports Server (NTRS)

Stella, Paul M.; West, John L.; Chave, Robert G.; Mcgee, David P.; Yen, Albert S.

1990-01-01

The suitability of the Advanced Photovoltaic Solar Array (APSA) for future space missions was examined by considering the impact on the spacecraft system in general. The lightweight flexible blanket array system was compared to rigid arrays and a radio-isotope thermoelectric generator (RTG) static power source for a wide range of assumed future earth orbiting and interplanetary mission applications. The study approach was to establish assessment criteria and a rating scheme, identify a reference mission set, perform the power system assessment for each mission, and develop conclusions and recommendations to guide future APSA technology development. The authors discuss the three selected power sources, the assessment criteria and rating definitions, and the reference missions. They present the assessment results in a convenient tabular format. It is concluded that the three power sources examined, APSA, conventional solar arrays, and RTGs, can be considered to complement each other. Each power technology has its own range of preferred applications.

Hybrid thermocouple development program

NASA Technical Reports Server (NTRS)

Garvey, L. P.; Krebs, T. R.; Lee, E.

1971-01-01

The design and development of a hybrid thermocouple, having a segmented SiGe-PbTe n-leg encapsulated within a hollow cylindrical p-SiGe leg, is described. Hybrid couple efficiency is calculated to be 10% to 15% better than that of a all-SiGe couple. A preliminary design of a planar RTG, employing hybrid couples and a water heat pipe radiator, is described as an example of a possible system application. Hybrid couples, fabricated initially, were characterized by higher than predicted resistance and, in some cases, bond separations. Couples made later in the program, using improved fabrication techniques, exhibited normal resistances, both as-fabricated and after 700 hours of testing. Two flat-plate sections of the reference design thermoelectric converter were fabricated and delivered to NASA Lewis for testing and evaluation.

KSC-97PC1092

NASA Image and Video Library

1997-07-19

Jet Propulsion Laboratory (JPL) worker Mary Reaves mates connectors on a radioisotope thermoelectric generator (RTG) to power up the Cassini spacecraft, while quality assurance engineer Peter Sorci looks on. The three RTGs which will be used on Cassini are undergoing mechanical and electrical verification testing in the Payload Hazardous Servicing Facility. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate at great distances from the Sun where solar power systems are not feasible. The Cassini mission is targeted for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed by JPL

KSC-97PC1070

NASA Image and Video Library

1997-07-18

Jet Propulsion Laboratory (JPL) workers use a borescope to verify pressure relief device bellows integrity on a radioisotope thermoelectric generator (RTG) which has been installed on the Cassini spacecraft in the Payload Hazardous Servicing Facility. The activity is part of the mechanical and electrical verification testing of RTGs during prelaunch processing. RTGs use heat from the natural decay of plutonium to generate electric power. The three RTGs on Cassini will enable the spacecraft to operate far from the Sun where solar power systems are not feasible. They will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. The Cassini mission is scheduled for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed for NASA by JPL

KSC-97PC1064

NASA Image and Video Library

1997-07-18

Jet Propulsion Laboratory (JPL) workers carefully roll into place a platform with a second radioisotope thermoelectric generator (RTG) for installation on the Cassini spacecraft. In background at left, the first of three RTGs already has been installed on Cassini. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. The power units are undergoing mechanical and electrical verification testing in the Payload Hazardous Servicing Facility. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate far from the Sun where solar power systems are not feasible. The Cassini mission is scheduled for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed for NASA by JPL

Modular Stirling Radioisotope Generator

NASA Technical Reports Server (NTRS)

Schmitz, Paul C.; Mason, Lee S.; Schifer, Nicholas A.

2015-01-01

High efficiency radioisotope power generators will play an important role in future NASA space exploration missions. Stirling Radioisotope Generators (SRG) have been identified as a candidate generator technology capable of providing mission designers with an efficient, high specific power electrical generator. SRGs high conversion efficiency has the potential to extend the limited Pu-238 supply when compared with current Radioisotope Thermoelectric Generators (RTG). Due to budgetary constraints, the Advanced Stirling Radioisotope Generator (ASRG) was canceled in the fall of 2013. Over the past year a joint study by NASA and DOE called the Nuclear Power Assessment Study (NPAS) recommended that Stirling technologies continue to be explored. During the mission studies of the NPAS, spare SRGs were sometimes required to meet mission power system reliability requirements. This led to an additional mass penalty and increased isotope consumption levied on certain SRG-based missions. In an attempt to remove the spare power system, a new generator architecture is considered which could increase the reliability of a Stirling generator and provide a more fault-tolerant power system. This new generator called the Modular Stirling Radioisotope Generator (MSRG) employs multiple parallel Stirling convertor/controller strings, all of which share the heat from the General Purpose Heat Source (GPHS) modules. For this design, generators utilizing one to eight GPHS modules were analyzed, which provide about 50 to 450 watts DC to the spacecraft, respectively. Four Stirling convertors are arranged around each GPHS module resulting in from 4 to 32 Stirling/controller strings. The convertors are balanced either individually or in pairs, and are radiatively coupled to the GPHS modules. Heat is rejected through the housing/radiator which is similar in construction to the ASRG. Mass and power analysis for these systems indicate that specific power may be slightly lower than the ASRG and similar to the MMRTG. However, the reliability should be significantly increased compared to ASRG.

Comparative Cytotoxicity Study of Silver Nanoparticles (AgNPs) in a Variety of Rainbow Trout Cell Lines (RTL-W1, RTH-149, RTG-2) and Primary Hepatocytes

PubMed Central

Connolly, Mona; Fernandez-Cruz, Maria-Luisa; Quesada-Garcia, Alba; Alte, Luis; Segner, Helmut; Navas, Jose M.

2015-01-01

Among all classes of nanomaterials, silver nanoparticles (AgNPs) have potentially an important ecotoxicological impact, especially in freshwater environments. Fish are particularly susceptible to the toxic effects of silver ions and, with knowledge gaps regarding the contribution of dissolution and unique particle effects to AgNP toxicity, they represent a group of vulnerable organisms. Using cell lines (RTL-W1, RTH-149, RTG-2) and primary hepatocytes of rainbow trout (Oncorhynchus mykiss) as in vitro test systems, we assessed the cytotoxicity of the representative AgNP, NM-300K, and AgNO3 as an Ag+ ion source. Lack of AgNP interference with the cytotoxicity assays (AlamarBlue, CFDA-AM, NRU assay) and their simultaneous application point to the compatibility and usefulness of such a battery of assays. The RTH-149 and RTL-W1 liver cell lines exhibited similar sensitivity as primary hepatocytes towards AgNP toxicity. Leibovitz’s L-15 culture medium composition (high amino acid content) had an important influence on the behaviour and toxicity of AgNPs towards the RTL-W1 cell line. The obtained results demonstrate that, with careful consideration, such an in vitro approach can provide valuable toxicological data to be used in an integrated testing strategy for NM-300K risk assessment. PMID:26006119

In vitro cellular responses in the RTG-2 cell line to complex mixtures of dioxins and dioxin-like PCDDs, PCDFs and PCBs.

PubMed

Babín, María del Mar; Sanz, Paloma; Concejero, Miguel Angel; Martínez, María Angeles; Tarazona, José Vicente

2010-08-01

High-resolution gas chromatography/mass spectrometry (HRGC/MS) is the standard method for analysing dioxin, furan and polybrominated retardants in hazardous waste. Determination of dioxin-like compounds using in vitro bioassays such as ethoxyresorufin-O-deethylase (EROD) is an important tool to evaluate their Ah receptor-mediated toxic effects, because it detects all arylhydrocarbon receptor ligands in a variety of sample matrices. In the present work, we compared RTG-2 cell line EROD bioassay with HRGC/MS for assessing waste samples (liquid and solid) contaminated with polychlorinated dibenzo-p-dioxins and dibenzofurans, polychlorinated biphenyls (dioxin-like PCBs) and other xenobiotics. For liquid samples, HRGC/MS-toxic equivalent (HRGC/MS-TEQ) values ranged from 273.26 to 5.84 ng TEQ l(-1) and correlated well (correlation coefficient 0.99) with values obtained by EROD-TEQ, which ranged from 128 to 2.5 ng TEQ l(-1). For solid samples, HRGC/MS-TEQ values ranged from 3.44 to 0.49 ng TEQ g(-1) and correlated less well than liquid samples (correlation coefficient 0.64) with values obtained by EROD-TEQ ranging from 2.27 to 0.93 ng TEQ g(-1). The overestimation of RTG-2 EROD-TEQ (1.2 +/- 0.92 of values established by HRGC/MS) and the absence of false-negative results may limit analytical costs by eliminating the need for follow-up GC/MS analysis on the negative samples. We suggest that RTG-2 EROD bioassay is an inexpensive means for preliminary dioxin and furan positive screenings of waste samples. (c) 2010 John Wiley & Sons, Ltd.

GPS Software Packages Deliver Positioning Solutions

NASA Technical Reports Server (NTRS)

2010-01-01

"To determine a spacecraft s position, the Jet Propulsion Laboratory (JPL) developed an innovative software program called the GPS (global positioning system)-Inferred Positioning System and Orbit Analysis Simulation Software, abbreviated as GIPSY-OASIS, and also developed Real-Time GIPSY (RTG) for certain time-critical applications. First featured in Spinoff 1999, JPL has released hundreds of licenses for GIPSY and RTG, including to Longmont, Colorado-based DigitalGlobe. Using the technology, DigitalGlobe produces satellite imagery with highly precise latitude and longitude coordinates and then supplies it for uses within defense and intelligence, civil agencies, mapping and analysis, environmental monitoring, oil and gas exploration, infrastructure management, Internet portals, and navigation technology."

Imaging the accumulation and suppression of tau pathology using multiparametric MRI

PubMed Central

Holmes, Holly E.; Colgan, Niall; Ismail, Ozama; Ma, Da; Powell, Nick M.; O'Callaghan, James M.; Harrison, Ian F.; Johnson, Ross A.; Murray, Tracey K.; Ahmed, Zeshan; Heggenes, Morton; Fisher, Alice; Cardoso, M.J.; Modat, Marc; Walker-Samuel, Simon; Fisher, Elizabeth M.C.; Ourselin, Sebastien; O'Neill, Michael J.; Wells, Jack A.; Collins, Emily C.; Lythgoe, Mark F.

2016-01-01

Mouse models of Alzheimer's disease have served as valuable tools for investigating pathogenic mechanisms relating to neurodegeneration, including tau-mediated and neurofibrillary tangle pathology—a major hallmark of the disease. In this work, we have used multiparametric magnetic resonance imaging (MRI) in a longitudinal study of neurodegeneration in the rTg4510 mouse model of tauopathy, a subset of which were treated with doxycycline at different time points to suppress the tau transgene. Using this paradigm, we investigated the sensitivity of multiparametric MRI to both the accumulation and suppression of pathologic tau. Tau-related atrophy was discernible from 5.5 months within the cortex and hippocampus. We observed markedly less atrophy in the treated rTg4510 mice, which was enhanced after doxycycline intervention from 3.5 months. We also observed differences in amide proton transfer, cerebral blood flow, and diffusion tensor imaging parameters in the rTg4510 mice, which were significantly less altered after doxycycline treatment. We propose that these non-invasive MRI techniques offer insight into pathologic mechanisms underpinning Alzheimer's disease that may be important when evaluating emerging therapeutics targeting one of more of these processes. PMID:26923415

Centaur in-tank explosion flow fields within STS and Titan 4 payload spaces

NASA Technical Reports Server (NTRS)

Eck, M.; Mukunda, M.

1988-01-01

Explosions are examined which result from the mixing of liquid hydrogen and liquid oxygen (LH2-LO2) such that the reactants are confined by the missile (CBM) body. Explosion which were confined by the ground surface (CBGS) were also studied, with results reported elsewhere. Initial attempts to predict the reported PYRO experimental results were unsuccessful. A new reaction energy addition hypothesis was then developed and tested. The results obtained provide reasonable agreement with the experiments both in the near and far field. Calculations were performed to predict the environment which would occur at the Galileo Radioisotope Thermoelectric Generator (RTG) location given a Centaur G' upper stage and an STS launch vehicle. It was concluded that the principle threat to the RTG in this environment would be the impact of a slug of LH2. No analyses were conducted to assess the response of the Galileo RTG to such an environment. It was shown that the flow field resulting from the failure of the Centaur G' tankage was benign. It was concluded that while the cryogen particle velocity was very high, the flow field density was extremely low. As a result, the dynamic pressure was a trivial eight psia.

Cassini's RTGs undergo mechanical and electrical verification tests in the PHSF

NASA Technical Reports Server (NTRS)

1997-01-01

Jet Propulsion Laboratory (JPL) worker Mary Reaves mates connectors on a radioisotope thermoelectric generator (RTG) to power up the Cassini spacecraft, while quality assurance engineer Peter Sorci looks on. The three RTGs which will be used on Cassini are undergoing mechanical and electrical verification testing in the Payload Hazardous Servicing Facility. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate at great distances from the Sun where solar power systems are not feasible. The Cassini mission is targeted for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed by JPL.

KSC-97PC1094

NASA Image and Video Library

1997-07-19

Jet Propulsion Laboratory (JPL) employees bolt a radioisotope thermoelectric generator (RTG) onto the Cassini spacecraft, at left, while other JPL workers, at right, operate the installation cart on a raised platform in the Payload Hazardous Servicing Facility (PHSF). Cassini will be outfitted with three RTGs. The power units are undergoing mechanical and electrical verification tests in the PHSF. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate at great distances from the Sun where solar power systems are not feasible. The Cassini mission is targeted for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed by JPL

Cassini's RTGs undergo mechanical and electrical verification testing in the PHSF

NASA Technical Reports Server (NTRS)

1997-01-01

Jet Propulsion Laboratory (JPL) workers carefully roll into place a platform with a second radioisotope thermoelectric generator (RTG) for installation on the Cassini spacecraft. In background at left, the first of three RTGs already has been installed on Cassini. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. The power units are undergoing mechanical and electrical verification testing in the Payload Hazardous Servicing Facility. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate far from the Sun where solar power systems are not feasible. The Cassini mission is scheduled for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed for NASA by JPL.

Thermal Expansion Studies of Selected High Temperature Thermoelectric Materials

NASA Technical Reports Server (NTRS)

Ravi, Vilupanur; Firdosy, Samad; Caillat, Thierry; Brandon, Erik; Van Der Walde, Keith; Maricic, Lina; Sayir, Ali

2008-01-01

Radioisotope thermoelectric generators (RTGs) generate electrical power by converting the heat released from the nuclear decay of radioactive isotopes (typically plutonium-238) into electricity using a thermoelectric converter. RTGs have been successfully used to power a number of space missions and have demonstrated their reliability over an extended period of time (tens of years) and are compact, rugged, radiation resistant, scalable, and produce no noise, vibration or torque during operation. System conversion efficiency for state-of-practice RTGs is about 6% and specific power less than or equal to 5.1 W/kg. Higher specific power would result in more on-board power for the same RTG mass, or less RTG mass for the same on-board power. The Jet Propulsion Laboratory has been leading, under the advanced thermoelectric converter (ATEC) project, the development of new high-temperature thermoelectric materials and components for integration into advanced, more efficient RTGs. Thermoelectric materials investigated to date include skutterudites, the Yb14MnSb11 compound, and SiGe alloys. The development of long-lived thermoelectric couples based on some of these materials has been initiated and is assisted by a thermo-mechanical stress analysis to ensure that all stresses under both fabrication and operation conditions will be within yield limits for those materials. Several physical parameters are needed as input to this analysis. Among those parameters, the coefficient of thermal expansion (CTE) is critically important. Thermal expansion coefficient measurements of several thermoelectric materials under consideration for ATEC are described in this paper. The stress response at the interfaces in material stacks subjected to changes in temperature is discussed, drawing on work from the literature and project-specific tools developed here. The degree of CTE mismatch and the associated effect on the formation of stress is highlighted.

Riverine ecosystem services and the thermoelectric sector: strategic issues facing the Northeastern United States

NASA Astrophysics Data System (ADS)

Miara, A.; Vorosmarty, C. J.; Stewart, R.; Wollheim, W. M.; Rosenzweig, B.

2013-12-01

Major strategic issues facing the global thermoelectric sector include environmental regulation, climate change and increasing electricity demand. We have addressed such issues by modeling thermoelectric generation in the Northeastern United States that is reliant on cooling under five sensitivity tests to evaluate losses/gains in power production, thermal pollution and suitable aquatic habitat, comparing the contemporary baseline (2000-2010) with potential future states. Integral to the analysis, we developed a methodology to quantify river water availability for cooling, which we define as an ecosystem service. Projected climate conditions reduce river water available for efficient power plant operations and the river's capacity to absorb waste heat, causing a loss of regional thermoelectric generation (RTG) (2.5%) in some summers that, compared to the contemporary baseline, is equal to the summertime electricity consumption of 1.3 million Northeastern US homes. Vulnerabilities to warm temperatures and thermal pollution can be alleviated through the use of more efficient natural gas (NG) power plants that have a reduced reliance on cooling water. Conversion of once-through (OT) to cooling tower (CT) systems and the Clean Water Act (CWA) temperature limit regulation, both of which reduce efficiencies at the single plant level, show potential to yield beneficial increases in RTG. This is achieved by obviating the need for large volumes of river water, thereby reducing plant-to-plant interferences through lowering the impact of upstream thermal pollution and preserving a minimum standard of cooling water. The results and methodology framework presented here, which can be extrapolated to other regional assessments with contrasting climates and thermoelectric profiles, can identify opportunities and support decision-making to achieve more efficient energy systems and riverine ecosystem protection.

Riverine ecosystem services and the thermoelectric sector: strategic issues facing the Northeastern United States

NASA Astrophysics Data System (ADS)

Miara, Ariel; Vörösmarty, Charles J.; Stewart, Robert J.; Wollheim, Wilfred M.; Rosenzweig, Bernice

2013-06-01

Major strategic issues facing the global thermoelectric sector include environmental regulation, climate change and increasing electricity demand. We have addressed such issues by modeling thermoelectric generation in the Northeastern United States that is reliant on cooling under five sensitivity tests to evaluate losses/gains in power production, thermal pollution and suitable aquatic habitat, comparing the contemporary baseline (2000-2010) with potential future states. Integral to the analysis, we developed a methodology to quantify river water availability for cooling, which we define as an ecosystem service. Projected climate conditions reduce river water available for efficient power plant operations and the river’s capacity to absorb waste heat, causing a loss of regional thermoelectric generation (RTG) (2.5%) in some summers that, compared to the contemporary baseline, is equal to the summertime electricity consumption of 1.3 million Northeastern US homes. Vulnerabilities to warm temperatures and thermal pollution can be alleviated through the use of more efficient natural gas (NG) power plants that have a reduced reliance on cooling water. Conversion of once-through (OT) to cooling tower (CT) systems and the Clean Water Act (CWA) temperature limit regulation, both of which reduce efficiencies at the single plant level, show potential to yield beneficial increases in RTG. This is achieved by obviating the need for large volumes of river water, thereby reducing plant-to-plant interferences through lowering the impact of upstream thermal pollution and preserving a minimum standard of cooling water. The results and methodology framework presented here, which can be extrapolated to other regional assessments with contrasting climates and thermoelectric profiles, can identify opportunities and support decision-making to achieve more efficient energy systems and riverine ecosystem protection.

Nuclear space power safety and facility guidelines study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mehlman, W.F.

1995-09-11

This report addresses safety guidelines for space nuclear reactor power missions and was prepared by The Johns Hopkins University Applied Physics Laboratory (JHU/APL) under a Department of Energy grant, DE-FG01-94NE32180 dated 27 September 1994. This grant was based on a proposal submitted by the JHU/APL in response to an {open_quotes}Invitation for Proposals Designed to Support Federal Agencies and Commercial Interests in Meeting Special Power and Propulsion Needs for Future Space Missions{close_quotes}. The United States has not launched a nuclear reactor since SNAP 10A in April 1965 although many Radioisotope Thermoelectric Generators (RTGs) have been launched. An RTG powered system ismore » planned for launch as part of the Cassini mission to Saturn in 1997. Recently the Ballistic Missile Defense Office (BMDO) sponsored the Nuclear Electric Propulsion Space Test Program (NEPSTP) which was to demonstrate and evaluate the Russian-built TOPAZ II nuclear reactor as a power source in space. As of late 1993 the flight portion of this program was canceled but work to investigate the attributes of the reactor were continued but at a reduced level. While the future of space nuclear power systems is uncertain there are potential space missions which would require space nuclear power systems. The differences between space nuclear power systems and RTG devices are sufficient that safety and facility requirements warrant a review in the context of the unique features of a space nuclear reactor power system.« less

Emitted radiation characteristics of plutonium dioxide radioisotope thermoelectric generators

NASA Technical Reports Server (NTRS)

Gingo, P. J.; Steyn, J. J.

1971-01-01

The nuclear and emitted radiation characteristics of the radioisotope elements and impurities in commercial grade plutonium dioxide are presented in detail. The development of the methods of analysis are presented. Radioisotope thermoelectric generators (RTG) of 1575, 3468 and 5679 thermal watts are characterized with respect to neutron and gamma photon source strength as well as spatial and number flux distribution. The results are presented as a function of detector position and light element contamination concentration for fuel age ranging from 'fresh' to 18 years. The data may be used to obtain results for given O-18 and Pu-236 concentrations. The neutron and gamma photon flux and dose calculations compare favorably with reported experimental values for SNAP-27.

Radioisotope Stirling Generator Options for Pluto Fast Flyby Mission

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schock, Alfred

The preceding paper described conceptual designs and analytical results for five Radioisotope Thermoelectric Generator (RTG) options for the Pluto Fast Flyby (PFF) mission, and the present paper describes three Radioisotope Stirling Generator (RSG) options for the same mission. The RSG options are based on essentially the same radioisotope heat source modules used in previously flown RTGs and on designs and analyses of a 75-watt free-piston Stirling engine produced by Mechanical Technology Incorporated (MTI) for NASA's Lewis Research Center. The integrated system design options presented were generated in a Fairchild Space study sponsored by the Department of Energy's Office of Specialmore » Applications, in support of ongoing PFF mission and spacecraft studies that the Jet Propulsion Laboratory (JPL) is conducting for the National Aeronautics and Space Administration (NASA). That study's NASA-directed goal is to reduce the spacecraft mass from its baseline value of 166 kg to ~110 kg, which implies a mass goal of less than 10 kg for a power source able to deliver 69 watts(e) at the end of the 9.2-year mission. In general, the Stirling options were found to be lighter than the thermoelectric options described in the preceding paper. But they are less mature, requiring more development, and entailing greater programmatic risk. The Stirling power system mass ranged from 7.3 kg (well below the 10-kg goal) for a non-redundant system to 11.3 kg for a redundant system able to maintain full power if one of its engines fails. In fact, the latter system could deliver as much as 115 watts(e) if desired by the mission planners. There are 2 copies in the file.« less

Bone Density, Balance and Quality of Life of Postmenopausal Women Taking Alendronate Participating in Different Physical Activity Programs

PubMed Central

Borba-Pinheiro, Cláudio Joaquim; de Alencar Carvalho, Mauro César Gurgel; da Silva, Nádia Souza Lima; Drigo, Alexandre Janotta; Bezerra, Jani Cléria Pereira; Dantas, Estélio Henrique Martin

2010-01-01

Background: The objective of this study was to determine the effects of different physical activity (PA) programs on bone density, balance and quality of Life of postmenopausaL women taking concomitant aLendronate. A quasi-experimental study was conducted with 35 volunteers divided into four groups: practitioners of resistance training (RTG, n = 9, 49.8±4.2 years), judo (JUG, n= 11, 52.2 ±5.3 years), water aerobics (WAG, n = 8, 57.1 ±7.4 years) and the control group (CG, n = 7, 53.8±4.4 years). Methods: The following assessment tools were used: bone mineral density (BMD) measured by dual X-ray absorptiometry of the spine and proximal femur, the ‘Osteoporosis Assessment Questionnaire’ (OPAQ) and the ‘Static Balance Test with Visual Control’. The physical activities were planned for 12 months in cycles with different intensities. A two-way analysis of variance (ANOVA) was used for analysis between groups, and a Scheffe post-hoc test was used for multiple comparisons. Results: The multiple comparisons results showed that the RTG and JUG groups were significantly more efficient in the variables studied, including: Lumbar BMD (Δ% = 6.8%, p = 0.001), balance (Δ% = 21.4%, p = 0.01), OPAQ (Δ% = 9.1%, p = 0.005) and Lumbar BMD (Δ% = 6.4%, p = 0.003), balance (Δ% = U%, p = 0.02) and OPAQ (Δ% = 16.8%, p =0.000) compared with the CG. Furthermore, the RTG (Δ% = 4.8%, p =0.02) was significantly better than the WAG for the neck of femur BMD, and the JUG (Δ% = 16.8, p = 0.0003) also demonstrated superiority to the WAG in the OPAQ. Conclusions: The physical activities studied appear to improve BMD, balance and quality of Life of postmenopausaL women taking a bisphosphonate. In this small sample, the RTG and the JUG groups were superior to the other groups. PMID:22870446

Differential growth of U and M type infectious haematopoietic necrosis virus in a rainbow trout–derived cell line, RTG-2

USGS Publications Warehouse

Kurath, Gael; Purcell, Maureen K.; Wargo, Andrew; Park, Jeong Woo; Moon, Chang Hoon

2010-01-01

Infectious haematopoietic necrosis virus (IHNV) is one of the most important viral pathogens of salmonids. In rainbow trout, IHNV isolates in the M genogroup are highly pathogenic, while U genogroup isolates are significantly less pathogenic. We show here that, at a multiplicity of infection (MOI) of 1, a representative U type strain yielded 42-fold less infectious virus than an M type strain in the rainbow trout–derived RTG-2 cell line at 24 h post-infection (p.i.). However, at an MOI of 10, there was only fivefold difference in the yield of infectious virus between the U and M strains. Quantification of extracellular viral genomic RNA suggested that the number of virus particles released from cells infected with the U strain at a MOI of 1 was 47-fold lower than from M-infected cells, but U and M virions were equally infectious by particle to infectivity ratios. At an MOI of 1, U strain intracellular viral genome accumulation and transcription were 37- and 12-fold lower, respectively, than those of the M strain at 24 h p.i. Viral nucleocapsid (N) protein accumulation in U strain infections was fivefold lower than in M strain infections. These results suggest that the block in U type strain growth in RTG-2 cells was because of the effects of reduced genome replication and transcription. The reduced growth of the U strain does not seem to be caused by defective genes, because the U and M strains grew equally well in the permissive epithelioma papulosum cyprini cell line at an MOI of 1. This suggests that host-specific factors in RTG-2 cells control the growth of the IHNV U and M strains differently, leading to growth restriction of the U type virus during the RNA synthesis step.

Electrical and Network Neuronal Properties Are Preferentially Disrupted in Dorsal, But Not Ventral, Medial Entorhinal Cortex in a Mouse Model of Tauopathy

PubMed Central

Booth, Clair A.; Ridler, Thomas; Murray, Tracey K.; Ward, Mark A.; de Groot, Emily; Goodfellow, Marc; Phillips, Keith G.; Randall, Andrew D.

2016-01-01

The entorhinal cortex (EC) is one of the first areas to be disrupted in neurodegenerative diseases such as Alzheimer's disease and frontotemporal dementia. The responsiveness of individual neurons to electrical and environmental stimuli varies along the dorsal–ventral axis of the medial EC (mEC) in a manner that suggests this topographical organization plays a key role in neural encoding of geometric space. We examined the cellular properties of layer II mEC stellate neurons (mEC-SCs) in rTg4510 mice, a rodent model of neurodegeneration. Dorsoventral gradients in certain intrinsic membrane properties, such as membrane capacitance and afterhyperpolarizations, were flattened in rTg4510 mEC-SCs, while other cellular gradients [e.g., input resistance (Ri), action potential properties] remained intact. Specifically, the intrinsic properties of rTg4510 mEC-SCs in dorsal aspects of the mEC were preferentially affected, such that action potential firing patterns in dorsal mEC-SCs were altered, while those in ventral mEC-SCs were unaffected. We also found that neuronal oscillations in the gamma frequency band (30–80 Hz) were preferentially disrupted in the dorsal mEC of rTg4510 slices, while those in ventral regions were comparatively preserved. These alterations corresponded to a flattened dorsoventral gradient in theta-gamma cross-frequency coupling of local field potentials recorded from the mEC of freely moving rTg4510 mice. These differences were not paralleled by changes to the dorsoventral gradient in parvalbumin staining or neurodegeneration. We propose that the selective disruption to dorsal mECs, and the resultant flattening of certain dorsoventral gradients, may contribute to disturbances in spatial information processing observed in this model of dementia. SIGNIFICANCE STATEMENT The medial entorhinal cortex (mEC) plays a key role in spatial memory and is one of the first areas to express the pathological features of dementia. Neurons of the mEC are anatomically arranged to express functional dorsoventral gradients in a variety of neuronal properties, including grid cell firing field spacing, which is thought to encode geometric scale. We have investigated the effects of tau pathology on functional dorsoventral gradients in the mEC. Using electrophysiological approaches, we have shown that, in a transgenic mouse model of dementia, the functional properties of the dorsal mEC are preferentially disrupted, resulting in a flattening of some dorsoventral gradients. Our data suggest that neural signals arising in the mEC will have a reduced spatial content in dementia. PMID:26758825

Radiation Measurements in Cruise and on Mars by the MSL Radiation Assessment Detector

NASA Astrophysics Data System (ADS)

Zeitlin, C. J.; Hassler, D.; Wimmer-Schweingruber, R. F.; Appel, J. K.; Boehm, E.; Boettcher, S.; Brinza, D.; Burmeister, S.; Cucinotta, F.; Ehresmann, B.; Guo, J.; Kohler, J.; Lohf, H.; Martin, C.; Posner, A.; Rafkin, S. C.; Reitz, G.; Team, M.

2013-12-01

The Radiation Assessment Detector (RAD) is one of ten science instruments on the Curiosity rover. The RAD team's science objectives include the measurement of radiation dose (a purely physical quantity) and dose equivalent (a derived quantity that can be related to cancer risk) on the surface of Mars. In addition, RAD acquired data for most of the cruise to Mars, from Dec. 2011 through July 2012, providing a measurement of the radiation environment under conditions similar to those expected on a human trip to Mars or other deep space destinations. The dose and dose equivalent measurements made during cruise have been published, but are presented in more detail here. Rates measured in cruise are compared to similar measurements made during Curiosity's first 269 sols on the surface of Mars. In the simplest picture, one expects rates to be a factor of two lower on the surface of a large airless body compared to free space, owing to the two-pi shielding geometry. The situation on Mars is complicated by the non-negligible shielding effects of the atmosphere, particularly in Gale Crater where diurnal variations in atmospheric column depth are significant. The diurnal variations - caused by the well-known thermal tides on Mars - result in reduced shielding of the surface in the afternoon as compared to the night and early morning hours. A major challenge in analyzing the surface data is the treatment of the background radiation dose coming from Curiosity's Radioisotope Thermoelectric Generator (RTG). Prior to launch, RAD acquired data in the full cruise configuration so that this background could be measured with only sea-level cosmic ray muons present - that is, almost all of what was measured was due to the RTG. Those effects could therefore be subtracted from the cruise measurements in a straightforward way. However, the situation on the surface is somewhat different than in cruise, in that the mass that was present above RAD - and caused scattering of particles into the detector - is no longer there. The RTG-induced dose rate in the surface configuration must therefore be less than it was in the cruise configuration, but there is no way to get a direct measurement of the background. Quantifying the change in RTG background is difficult but essential, as the subtraction affects every aspect of the dosimetry. Two approaches have been developed and yield roughly similar results. The differences allow us to estimate the uncertainties arising from the RTG subtraction, and propagate those into the dosimetry results.

A Simple Technique for Creating Regional Composites of Sea Surface Temperature from MODIS for Use in Operational Mesoscale NWP

NASA Technical Reports Server (NTRS)

Knievel, Jason C.; Rife, Daran L.; Grim, Joseph A.; Hahmann, Andrea N.; Hacker, Joshua P.; Ge, Ming; Fisher, Henry H.

2010-01-01

This paper describes a simple technique for creating regional, high-resolution, daytime and nighttime composites of sea surface temperature (SST) for use in operational numerical weather prediction (NWP). The composites are based on observations from NASA s Moderate Resolution Imaging Spectroradiometer (MODIS) aboard Aqua and Terra. The data used typically are available nearly in real time, are applicable anywhere on the globe, and are capable of roughly representing the diurnal cycle in SST. The composites resolution is much higher than that of many other standard SST products used for operational NWP, including the low- and high-resolution Real-Time Global (RTG) analyses. The difference in resolution is key because several studies have shown that highly resolved SSTs are important for driving the air sea interactions that shape patterns of static stability, vertical and horizontal wind shear, and divergence in the planetary boundary layer. The MODIS-based composites are compared to in situ observations from buoys and other platforms operated by the National Data Buoy Center (NDBC) off the coasts of New England, the mid-Atlantic, and Florida. Mean differences, mean absolute differences, and root-mean-square differences between the composites and the NDBC observations are all within tenths of a degree of those calculated between RTG analyses and the NDBC observations. This is true whether or not one accounts for the mean offset between the skin temperatures of the MODIS dataset and the bulk temperatures of the NDBC observations and RTG analyses. Near the coast, the MODIS-based composites tend to agree more with NDBC observations than do the RTG analyses. The opposite is true away from the coast. All of these differences in point-wise comparisons among the SST datasets are small compared to the 61.08C accuracy of the NDBC SST sensors. Because skin-temperature variations from land to water so strongly affect the development and life cycle of the sea breeze, this phenomenon was chosen for demonstrating the use of the MODIS-based composite in an NWP model. A simulated sea breeze in the vicinity of New York City and Long Island shows a small, net, but far from universal improvement when MODIS-based composites are used in place of RTG analyses. The timing of the sea breeze s arrival is more accurate at some stations, and the near-surface temperature, wind, and humidity within the breeze are more realistic.

Potential civil mission applications for space nuclear power systems

NASA Technical Reports Server (NTRS)

Ambrus, J. H.; Beatty, R. G. G.

1985-01-01

It is pointed out that the energy needs of spacecraft over the last 25 years have been met by photovoltaic arrays with batteries, primary fuel cells, and radioisotope thermoelectric generators (RTG). However, it might be difficult to satisfy energy requirements for the next generation of space missions with the currently used energy sources. Applications studies have emphasized the need for a lighter, cheaper, and more compact high-energy source than the scaling up of current technologies would permit. These requirements could be satisfied by a nuclear reactor power system. The joint NASA/DOD/DOE SP-100 program is to explore and evaluate this option. Critical elements of the technology are also to be developed, taking into account space reactor systems of the 100 kW class. The present paper is concerned with some of the civil mission categories and concepts which are enabled or significantly enhanced by the performance characteristics of a nuclear reactor energy system.

Cassini's RTGs undergo mechanical and electrical verification tests in the PHSF

NASA Technical Reports Server (NTRS)

1997-01-01

Jet Propulsion Laboratory (JPL) employees bolt a radioisotope thermoelectric generator (RTG) onto the Cassini spacecraft, at left, while other JPL workers, at right, operate the installation cart on a raised platform in the Payload Hazardous Servicing Facility (PHSF). Cassini will be outfitted with three RTGs. The power units are undergoing mechanical and electrical verification tests in the PHSF. The RTGs will provide electrical power to Cassini on its 6.7-year trip to the Saturnian system and during its four-year mission at Saturn. RTGs use heat from the natural decay of plutonium to generate electric power. The generators enable spacecraft to operate at great distances from the Sun where solar power systems are not feasible. The Cassini mission is targeted for an Oct. 6 launch aboard a Titan IVB/Centaur expendable launch vehicle. Cassini is built and managed by JPL.

Magnetic gradiometer for underwater detection applications

NASA Astrophysics Data System (ADS)

Kumar, S.; Skvoretz, D. C.; Moeller, C. R.; Ebbert, M. J.; Perry, A. R.; Ostrom, R. K.; Tzouris, A.; Bennett, S. L.; Czipott, P. V.; Sulzberger, G.; Allen, G. I.; Bono, J.; Clem, T. R.

2006-05-01

We have designed and constructed a magnetic gradiometer for underwater mine detection, location and tracking. The United States Naval Surface Warfare Center (NSWC PC) in Panama City, FL has conducted sea tests of the system using an unmanned underwater vehicle (UUV). The Real-Time Tracking Gradiometer (RTG) measures the magnetic field gradients caused by the presence of a mine in the Earth's magnetic field. These magnetic gradients can then be used to detect and locate a target with the UUV in motion. Such a platform can also be used for other applications, including the detection and tracking of vessels and divers for homeland (e.g., port) security and the detection of underwater pipelines. Data acquired by the RTG in sea tests is presented in this paper.

Utilizing Radioisotope Power System Waste Heat for Spacecraft Thermal Management

NASA Technical Reports Server (NTRS)

Pantano, David R.; Dottore, Frank; Tobery, E. Wayne; Geng, Steven M.; Schreiber, Jeffrey G.; Palko, Joseph L.

2005-01-01

An advantage of using a Radioisotope Power System (RPS) for deep space or planetary surface missions is the readily available waste heat, which can be used for a number of beneficial purposes including: maintaining electronic components within a controlled temperature range, warming propulsion tanks and mobility actuators, and maintaining liquid propellants above their freezing temperature. Previous missions using Radioisotope Thermoelectric Generators (RTGs) dissipated large quantities of waste heat due to the low efficiency of the thermoelectric conversion technology. The next generation RPSs, such as the 110-Watt Stirling Radioisotope Generator (SRG110) will have higher conversion efficiencies, thereby rejecting less waste heat at a lower temperature and may require alternate approaches to transferring waste heat to the spacecraft. RTGs, with efficiencies of 6 to 7 percent, reject their waste heat at the relatively high heat rejection temperature of 200 C. This is an advantage when rejecting heat to space; however, transferring heat to the internal spacecraft components requires a large and heavy radiator heat exchanger. At the same time, sensitive spacecraft instruments must be shielded from the thermal radiation of the RTG. The SRG110, with an efficiency around 22 percent and 50 C nominal housing surface temperature, can readily transfer the available waste heat directly via heat pipes, thermal straps, or fluid loops. The lower temperatures associated with the SRG110 avoid the chances of overheating other scientific components, eliminating the need for thermal shields. This provides the spacecraft designers more flexibility when locating the generator for a specific mission. A common misconception with high-efficiency systems is that there is not enough waste heat for spacecraft thermal management. This paper will dispel this misconception and investigate the use of a high-efficiency SRG110 for spacecraft thermal management and outline potential methods of waste heat utilization in several conceptual missions (Lunar Rover, Mars Rover, and Titan Lander). The advantages associated with the SRG110 as they relate to ease of assembly, less complex interfaces, and overall mass savings for a spacecraft will be highlighted.

KSC-2011-6652

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- Workers reconnect the coolant hoses to the shipping cask enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission upon its arrival in the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida. Coolant flows through the hoses to dissipate any excess heat generated by the MMRTG. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6666

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the RTG storage facility at NASA's Kennedy Space Center in Florida, the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission, with guide rods still installed on its support base, has been uncovered on the high bay floor. The MMRTG no longer needs supplemental cooling since any excess heat generated can dissipate into the air in the high bay. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6665

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, the external and internal protective layers of the shipping cask are lifted away from the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission. The MMRTG no longer needs supplemental cooling since any excess heat generated can dissipate into the air in the high bay. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6646

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- The multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory (MSL) mission, enclosed in a shipping cask in the MMRTG trailer, arrives at the RTG storage facility at NASA's Kennedy Space Center in Florida. During transport, coolant flows through hoses connected to the cask to dissipate any excess heat generated by the MMRTG. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

Digital control and data acquisition for high-value GTA welding

NASA Astrophysics Data System (ADS)

George, T. G.; Franco-Ferreira, E. A.

Electric power for the Cassini space probe will be provided by radioisotope thermoelectric generators (RTG's) thermally driven by General-Purpose Heat Source (GPHS) modules. Each GPHS module contains four, 150-g, pellets of Pu-238O2, and each of the four pellets is encapsulated within a thin-wall iridium-alloy shell. GTA girth welding of these capsules is performed at Los Alamos National Laboratory (LANL) on an automated, digitally-controlled welding system. Baseline design considerations for system automation and strategies employed to maximize process yield, improve process consistency, and generate required quality assurance information are discussed. Design of the automated girth welding system was driven by a number of factors which militated for precise parametric control and data acquisition. Foremost among these factors was the extraordinary value of the capsule components. In addition, DOE order 5700.6B, which took effect on 23 Sep. 1986, required that all operations adhere to strict levels of process quality assurance. A detailed technical specification for the GPHS welding system was developed on the basis of a joint LANL/Westinghouse Savannah River Company (WSRC) design effort. After a competitive bidding process, Jetline Engineering, Inc., of Irvine, California, was selected as the system manufacturer. During the period over which four identical welding systems were fabricated, very close liason was maintained between the LANL/WSRC technical representatives and the vendor. The level of rapport was outstanding, and the end result was the 1990 delivery of four systems that met or exceeded all specification requirements.

Environmental analysis of the logistics of agricultural products from roof top greenhouses in Mediterranean urban areas.

PubMed

Sanyé-Mengual, Esther; Cerón-Palma, Ileana; Oliver-Solà, Jordi; Montero, Juan Ignacio; Rieradevall, Joan

2013-01-15

As urban populations increase so does the amount of food transported to cities worldwide, and innovative agro-urban systems are being developed to integrate agricultural production into buildings; for example, by using roof top greenhouses (RTGs). This paper aims to quantify and compare, through a life cycle assessment, the environmental impact of the current linear supply system with a RTG system by using a case study for the production of tomatoes. The main results indicate that a change from the current linear system to the RTG system could result in a reduction, per kilogram of tomatoes (the functional unit), in the range of 44.4-75.5% for the different impact categories analysed, and savings of up to 73.5% in energy requirements. These savings are associated with re-utilisation of packaging systems (55.4-85.2%), minimisation of transport requirements (7.6-15.6%) and reduction of the loss of product during transportation and retail stages (7.3-37%). The RTG may become a strategic factor in the design of low-carbon cities in Mediterranean areas. Short-term implementation in the city of Barcelona could result in savings of 66.1 tonnes of CO₂ eq. ha(-1) when considering the global warming potential, and of 71.03 t ha(-1) when considering that the transformation from woodland to agricultural land is avoided. Copyright © 2012 Society of Chemical Industry.

Radioisotopic Thermoelectric Generator (RTG) Surveillance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mulford, Roberta Nancy

2016-09-29

This lecture discusses stockpile stewardship efforts and the role surveillance plays in the process. Performance of the RTGs is described, and the question of the absence of anticipated He is addressed.

Regulatory regions in the promoters of the Saccharomyces cerevisiae PYC1 and PYC2 genes encoding isoenzymes of pyruvate carboxylase.

PubMed

Menéndez, J; Gancedo, C

1998-07-15

We have identified regions in the promoters of the PYC1 and PYC2 genes from Saccharomyces cerevisiae involved in their regulation in different culture conditions. In the case of PYC1, a UAS in the region between -330/-297 and three repressing sequences with the common central core CCGCC at positions -457, -432 and -399 were identified. Specific binding of nuclear proteins to the -330/-214 DNA fragment was abolished in rtg mutants suggesting a role for the RTG genes in the control of PYC1 expression. In the case of the PYC2 promoter, elimination of a fragment from -417 to -291 brings about a two-fold decrease in the expression in repressed conditions and a similar increase in derepression.

The Sensorless Pore Module of Voltage-gated K+ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine.

PubMed

Syeda, Ruhma; Santos, Jose S; Montal, Mauricio

2016-02-05

KCNQ (voltage-gated K(+) channel family 7 (Kv7)) channels control cellular excitability and underlie the K(+) current sensitive to muscarinic receptor signaling (the M current) in sympathetic neurons. Here we show that the novel anti-epileptic drug retigabine (RTG) modulates channel function of pore-only modules (PMs) of the human Kv7.2 and Kv7.3 homomeric channels and of Kv7.2/3 heteromeric channels by prolonging the residence time in the open state. In addition, the Kv7 channel PMs are shown to recapitulate the single-channel permeation and pharmacological specificity characteristics of the corresponding full-length proteins in their native cellular context. A mutation (W265L) in the reconstituted Kv7.3 PM renders the channel insensitive to RTG and favors the conductive conformation of the PM, in agreement to what is observed when the Kv7.3 mutant is heterologously expressed. On the basis of the new findings and homology models of the closed and open conformations of the Kv7.3 PM, we propose a structural mechanism for the gating of the Kv7.3 PM and for the site of action of RTG as a Kv7.2/Kv7.3 K(+) current activator. The results validate the modular design of human Kv channels and highlight the PM as a high-fidelity target for drug screening of Kv channels. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

The Sensorless Pore Module of Voltage-gated K+ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine*

PubMed Central

Syeda, Ruhma; Santos, Jose S.; Montal, Mauricio

2016-01-01

KCNQ (voltage-gated K+ channel family 7 (Kv7)) channels control cellular excitability and underlie the K+ current sensitive to muscarinic receptor signaling (the M current) in sympathetic neurons. Here we show that the novel anti-epileptic drug retigabine (RTG) modulates channel function of pore-only modules (PMs) of the human Kv7.2 and Kv7.3 homomeric channels and of Kv7.2/3 heteromeric channels by prolonging the residence time in the open state. In addition, the Kv7 channel PMs are shown to recapitulate the single-channel permeation and pharmacological specificity characteristics of the corresponding full-length proteins in their native cellular context. A mutation (W265L) in the reconstituted Kv7.3 PM renders the channel insensitive to RTG and favors the conductive conformation of the PM, in agreement to what is observed when the Kv7.3 mutant is heterologously expressed. On the basis of the new findings and homology models of the closed and open conformations of the Kv7.3 PM, we propose a structural mechanism for the gating of the Kv7.3 PM and for the site of action of RTG as a Kv7.2/Kv7.3 K+ current activator. The results validate the modular design of human Kv channels and highlight the PM as a high-fidelity target for drug screening of Kv channels. PMID:26627826

DEVELOPMENT OF AN ENVIRONMENTAL ESTROGEN SCREEN USING TRANSIENTLY TRANSFECTED RAINBOW TROUT CELL LINES

EPA Science Inventory

Rainbow troutp hepatoma (RTH-149) and gonad cells (RTG-2) were used to develop a screening protocol for estrogen disrupting chemicals. Transfection of an estrogen-responsive luciferase reporter plasmid into...

KSC-2011-6664

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, a Department of Energy contractor employee guides the external and internal protective layers of the shipping cask as they are lifted from around the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission. The MMRTG no longer needs supplemental cooling since any excess heat generated can dissipate into the air in the high bay. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6651

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- The multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission, enclosed in a shipping cask, rolls into the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6658

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, a crane lifts the shipping cask enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission from its transportation pallet. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6647

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- The multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission, enclosed in a shipping cask, is seen through the open door of the MMRTG trailer that delivered it to the RTG storage facility at NASA's Kennedy Space Center in Florida. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6650

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- Workers use a forklift to transport the shipping cask enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission to the door of the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6648

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- Workers use a forklift to offload the shipping cask enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission from the MMRTG trailer that delivered it to the RTG storage facility at NASA's Kennedy Space Center in Florida. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6653

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, measurements are taken to determine the level of radioactivity emitted from the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission, enclosed in a shipping cask in the background. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6662

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, Department of Energy contractor employees remove the external and internal protective layers of the shipping cask enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6663

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, the external and internal protective layers of the shipping cask are lifted from around the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6659

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the RTG storage facility at NASA's Kennedy Space Center in Florida, the shipping cask enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission is lowered to the floor of the high bay in preparation for lifting the cask from around the MMRTG. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6649

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- Workers use a forklift to offload the shipping cask enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission from the MMRTG trailer that delivered it to the RTG storage facility at NASA's Kennedy Space Center in Florida. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6660

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, the shipping cask enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission is lifted from around the MMRTG using guide rods installed on the support base. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

Thermoelectric Outer Planets Spacecraft (TOPS)

NASA Technical Reports Server (NTRS)

1973-01-01

The research and advanced development work is reported on a ballistic-mode, outer planet spacecraft using radioisotope thermoelectric generator (RTG) power. The Thermoelectric Outer Planet Spacecraft (TOPS) project was established to provide the advanced systems technology that would allow the realistic estimates of performance, cost, reliability, and scheduling that are required for an actual flight mission. A system design of the complete RTG-powered outer planet spacecraft was made; major technical innovations of certain hardware elements were designed, developed, and tested; and reliability and quality assurance concepts were developed for long-life requirements. At the conclusion of its active phase, the TOPS Project reached its principal objectives: a development and experience base was established for project definition, and for estimating cost, performance, and reliability; an understanding of system and subsystem capabilities for successful outer planets missions was achieved. The system design answered long-life requirements with massive redundancy, controlled by on-board analysis of spacecraft performance data.

RTG-History, the Curiosity, Voyager, and New Horizons

Science.gov Websites

solar system for many years. Prior to New Horizons, the Apollo missions to the Moon, the Viking missions Report, January 11, 1991--April 30, 1998, DOE Technical Report Download Adobe PDF Reader , August 1998

Gravitational Lens: Deep Space Probe Design

DTIC Science & Technology

2012-03-01

Lieutenant, USAF Approved: Timothy Lawrence, Col, USAF (Chairman) Date Carl Hartsfield, Lt Col, USAF (Member) Date Marc G. Millis (Member) Date Abstract A...23 RTG Radioisotope Thermoelectric Generators . . . . . . . . . . . . . . . . . 26 EOL End of Life...26 ASRG Advanced Stirling Radioisotope Generator . . . . . . . . . . . . . . . . 26 GPHS

Potential health risks from postulated accidents involving the Pu-238 RTG on the Ulysses solar exploration mission

NASA Technical Reports Server (NTRS)

Goldman, Marvin; Hoover, Mark D.; Nelson, Robert C.; Templeton, William; Bollinger, Lance; Anspaugh, Lynn

1991-01-01

Potential radiation impacts from launch of the Ulysses solar exploration experiment were evaluated using eight postulated accident scenarios. Lifetime individual dose estimates rarely exceeded 1 mrem. Most of the potential health effects would come from inhalation exposures immediately after an accident, rather than from ingestion of contaminated food or water, or from inhalation of resuspended plutonium from contaminated ground. For local Florida accidents (that is, during the first minute after launch), an average source term accident was estimated to cause a total added cancer risk of up to 0.2 deaths. For accidents at later time after launch, a worldwide cancer risk of up to three cases was calculated (with a four in a million probability). Upper bound estimates were calculated to be about 10 times higher.

In vitro screening of organotin compounds and sediment extracts for cytotoxicity to fish cells.

PubMed

Giltrap, Michelle; Macken, Ailbhe; McHugh, Brendan; McGovern, Evin; Foley, Barry; Davoren, Maria

2011-01-01

The present study reports an in vitro screening method for contaminants in sediment samples utilizing an RTG-2 cell line. This technique integrates cytotoxicity testing with analytical chemistry with the aim of achieving a toxicity evaluation of the sediment sample. The toxic effect of individual organotin (OT) compounds and their presence in the sediment sample is the focus of the present study; however, other contaminants are also discussed. The following OT compounds: tributyltin (TBT), dibutyltin (DBT), monobutyltin (MBT), triphenyltin (TPT), diphenyltin (DPT), and a sediment solvent extract are exposed to the RTG-2 fish cell line. Both the alamar blue (AB) and neutral red (NR) assays are used to assess cytotoxicity after 24-h and 96-h exposure. Methodology for preparation of a sediment solvent extract suitable for biological testing and analytical determination is also described. With the RTG-2 cells, the AB and NR assays had comparable sensitivity for each individual OT compound exposure after 24 h, with TPT being the most toxic compound tested. The individual OT compound concentrations required to induce a 50% toxic effect on the cells (369 ng ml⁻¹ TBT, 1,905 ng ml⁻¹ DBT) did not equate to the concentrations of these contaminants present in the sediment extract that induced a 50% effect on the cells (294 ng ml⁻¹ TBT, 109 ng ml⁻¹ DBT). The solvent extract therefore exhibited a greater toxicity, and this suggests that the toxic effects observed were not due to OT compounds alone. The presence of other contaminants in the solvent extract is confirmed with chemical analysis, warranting further toxicity testing of contaminant mixtures and exposure to the cell line to further elucidate a complete toxicity evaluation. © 2010 SETAC.

KSC-2011-6654

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, Innovative Health Applications employee Mike McPherson measures the level of radioactivity emitted from the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission, enclosed in a shipping cask at right. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6661

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, Innovative Health Applications employee David Lake measures the level of radioactivity emitted from the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission as the external protective layer of the shipping cask is removed. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6656

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, Department of Energy contractor employees attach cables to the shipping cask enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission during preparations to lift it from its transportation pallet. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6655

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, preparations are under way to attach the shipping cask enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission to the cables that will lift it from its transportation pallet. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

KSC-2011-6657

NASA Image and Video Library

2011-06-30

CAPE CANAVERAL, Fla. -- In the high bay of the RTG storage facility at NASA's Kennedy Space Center in Florida, a Department of Energy contractor employee attaches a crane to the shipping cask enclosing the multi-mission radioisotope thermoelectric generator (MMRTG) for NASA's Mars Science Laboratory mission during preparations to lift it from its transportation pallet. The MMRTG will generate the power needed for the mission from the natural decay of plutonium-238, a non-weapons-grade form of the radioisotope. Heat given off by this natural decay will provide constant power through the day and night during all seasons. Waste heat from the MMRTG will be circulated throughout the rover system to keep instruments, computers, mechanical devices and communications systems within their operating temperature ranges. MSL's components include a compact car-sized rover, Curiosity, which has 10 science instruments designed to search for evidence on whether Mars has had environments favorable to microbial life, including chemical ingredients for life. The unique rover will use a laser to look inside rocks and release its gasses so that the rover’s spectrometer can analyze and send the data back to Earth. Launch of MSL aboard a United Launch Alliance Atlas V rocket is scheduled for Nov. 25 from Space Launch Complex 41 on Cape Canaveral Air Force Station in Florida. For more information, visit http://www.nasa.gov/msl. Photo credit: NASA/Frankie Martin

Hyperactivity with Agitative-Like Behavior in a Mouse Tauopathy Model.

PubMed

Jul, Pia; Volbracht, Christiane; de Jong, Inge E M; Helboe, Lone; Elvang, Anders Brandt; Pedersen, Jan Torleif

2016-01-01

Tauopathies, such as Alzheimer's disease (AD) and frontotemporal dementia (FTD), are characterized by formation of neurofibrillary tangles consisting of hyperphosphorylated tau. In addition to memory loss, patients experience behavioral symptoms such as agitation, aggression, depression, and insomnia. We explored the behavioral phenotype of a mouse model (rTg4510) carrying the human tau P301L mutation found in a familial form of FTD. We tested these mice in locomotor activity assays as well as in the Morris water maze to access spatial memory. In addition to cognitive impairments, rTg4510 mice exhibited a hyperactivity phenotype which correlated with progression of tau pathology and was dependent on P301L tau transgene expression. The hyperactive phenotype was characterized by significantly increased locomotor activity in a novel and in a simulated home cage environment together with a disturbed day/night cycle. The P301L-tau-dependent hyperactivity and agitative-like phenotype suggests that these mice may form a correlate to some of the behavioral disturbances observed in advanced AD and FTD.

Disrupted hippocampal sharp‐wave ripple‐associated spike dynamics in a transgenic mouse model of dementia

PubMed Central

Witton, Jonathan; Staniaszek, Lydia E.; Bartsch, Ullrich; Randall, Andrew D.; Jones, Matthew W.

2015-01-01

Key points High frequency (100–250 Hz) neuronal oscillations in the hippocampus, known as sharp‐wave ripples (SWRs), synchronise the firing behaviour of groups of neurons and play a key role in memory consolidation.Learning and memory are severely compromised in dementias such as Alzheimer's disease; however, the effects of dementia‐related pathology on SWRs are unknown.The frequency and temporal structure of SWRs was disrupted in a transgenic mouse model of tauopathy (one of the major hallmarks of several dementias).Excitatory pyramidal neurons were more likely to fire action potentials in a phase‐locked manner during SWRs in the mouse model of tauopathy; conversely, inhibitory interneurons were less likely to fire phase‐locked spikes during SWRs.These findings indicate there is reduced inhibitory control of hippocampal network events and point to a novel mechanism which may underlie the cognitive impairments in this model of dementia. Abstract Neurons within the CA1 region of the hippocampus are co‐activated during high frequency (100–250 Hz) sharp‐wave ripple (SWR) activity in a manner that probably drives synaptic plasticity and promotes memory consolidation. In this study we have used a transgenic mouse model of dementia (rTg4510 mice), which overexpresses a mutant form of tau protein, to examine the effects of tauopathy on hippocampal SWRs and associated neuronal firing. Tetrodes were used to record simultaneous extracellular action potentials and local field potentials from the dorsal CA1 pyramidal cell layer of 7‐ to 8‐month‐old wild‐type and rTg4510 mice at rest in their home cage. At this age point these mice exhibit neurofibrillary tangles, neurodegeneration and cognitive deficits. Epochs of sleep or quiet restfulness were characterised by minimal locomotor activity and a low theta/delta ratio in the local field potential power spectrum. SWRs detected off‐line were significantly lower in amplitude and had an altered temporal structure in rTg4510 mice. Nevertheless, the average frequency profile and duration of the SWRs were relatively unaltered. Putative interneurons displayed significantly less temporal and phase locking to SWRs in rTg4510 mice, whilst putative pyramidal neurons showed increased temporal and phase locking to SWRs. These findings indicate there is reduced inhibitory control of hippocampal network events and point to a novel mechanism which may contribute to impairments in memory consolidation in this model of dementia. PMID:25480798

Disrupted hippocampal sharp-wave ripple-associated spike dynamics in a transgenic mouse model of dementia.

PubMed

Witton, Jonathan; Staniaszek, Lydia E; Bartsch, Ullrich; Randall, Andrew D; Jones, Matthew W; Brown, Jonathan T

2016-08-15

High frequency (100-250 Hz) neuronal oscillations in the hippocampus, known as sharp-wave ripples (SWRs), synchronise the firing behaviour of groups of neurons and play a key role in memory consolidation. Learning and memory are severely compromised in dementias such as Alzheimer's disease; however, the effects of dementia-related pathology on SWRs are unknown. The frequency and temporal structure of SWRs was disrupted in a transgenic mouse model of tauopathy (one of the major hallmarks of several dementias). Excitatory pyramidal neurons were more likely to fire action potentials in a phase-locked manner during SWRs in the mouse model of tauopathy; conversely, inhibitory interneurons were less likely to fire phase-locked spikes during SWRs. These findings indicate there is reduced inhibitory control of hippocampal network events and point to a novel mechanism which may underlie the cognitive impairments in this model of dementia. Neurons within the CA1 region of the hippocampus are co-activated during high frequency (100-250 Hz) sharp-wave ripple (SWR) activity in a manner that probably drives synaptic plasticity and promotes memory consolidation. In this study we have used a transgenic mouse model of dementia (rTg4510 mice), which overexpresses a mutant form of tau protein, to examine the effects of tauopathy on hippocampal SWRs and associated neuronal firing. Tetrodes were used to record simultaneous extracellular action potentials and local field potentials from the dorsal CA1 pyramidal cell layer of 7- to 8-month-old wild-type and rTg4510 mice at rest in their home cage. At this age point these mice exhibit neurofibrillary tangles, neurodegeneration and cognitive deficits. Epochs of sleep or quiet restfulness were characterised by minimal locomotor activity and a low theta/delta ratio in the local field potential power spectrum. SWRs detected off-line were significantly lower in amplitude and had an altered temporal structure in rTg4510 mice. Nevertheless, the average frequency profile and duration of the SWRs were relatively unaltered. Putative interneurons displayed significantly less temporal and phase locking to SWRs in rTg4510 mice, whilst putative pyramidal neurons showed increased temporal and phase locking to SWRs. These findings indicate there is reduced inhibitory control of hippocampal network events and point to a novel mechanism which may contribute to impairments in memory consolidation in this model of dementia. © 2014 The Authors. The Journal of Physiology © 2014 The Physiological Society.

Metallic Junction Thermoelectric Device Simulations

NASA Technical Reports Server (NTRS)

Duzik, Adam J.; Choi, Sang H.

2017-01-01

Thermoelectric junctions made of semiconductors have existed in radioisotope thermoelectric generators (RTG) for deep space missions, but are currently being adapted for terrestrial energy harvesting. Unfortunately, these devices are inefficient, operating at only 7% efficiency. This low efficiency has driven efforts to make high-figure-of-merit thermoelectric devices, which require a high electrical conductivity but a low thermal conductivity, a combination that is difficult to achieve. Lowered thermal conductivity has increased efficiency, but at the cost of power output. An alternative setup is to use metallic junctions rather than semiconductors as thermoelectric devices. Metals have orders of magnitude more electrons and electronic conductivities higher than semiconductors, but thermal conductivity is higher as well. To evaluate the viability of metallic junction thermoelectrics, a two dimensional heat transfer MATLAB simulation was constructed to calculate efficiency and power output. High Seebeck coefficient alloys, Chromel (90%Ni-10%Cr) and Constantan (55%Cu-45%Ni), produced efficiencies of around 20-30%. Parameters such as the number of layers of junctions, lateral junction density, and junction sizes for both series- and parallel-connected junctions were explored.

Hsp90 activator Aha1 drives production of pathological tau aggregates

PubMed Central

Shelton, Lindsey B.; Baker, Jeremy D.; Zheng, Dali; Sullivan, Leia E.; Solanki, Parth K.; Webster, Jack M.; Sun, Zheying; Sabbagh, Jonathan J.; Nordhues, Bryce A.; Koren, John; Ghosh, Suman; Blagg, Brian S. J.; Dickey, Chad A.

2017-01-01

The microtubule-associated protein tau (MAPT, tau) forms neurotoxic aggregates that promote cognitive deficits in tauopathies, the most common of which is Alzheimer’s disease (AD). The 90-kDa heat shock protein (Hsp90) chaperone system affects the accumulation of these toxic tau species, which can be modulated with Hsp90 inhibitors. However, many Hsp90 inhibitors are not blood–brain barrier-permeable, and several present associated toxicities. Here, we find that the cochaperone, activator of Hsp90 ATPase homolog 1 (Aha1), dramatically increased the production of aggregated tau. Treatment with an Aha1 inhibitor, KU-177, dramatically reduced the accumulation of insoluble tau. Aha1 colocalized with tau pathology in human brain tissue, and this association positively correlated with AD progression. Aha1 overexpression in the rTg4510 tau transgenic mouse model promoted insoluble and oligomeric tau accumulation leading to a physiological deficit in cognitive function. Overall, these data demonstrate that Aha1 contributes to tau fibril formation and neurotoxicity through Hsp90. This suggests that therapeutics targeting Aha1 may reduce toxic tau oligomers and slow or prevent neurodegenerative disease progression. PMID:28827321

NCEP SST Analysis

Science.gov Websites

Branches Global Climate & Weather Modeling Mesoscale Modeling Marine Modeling and Analysis Contact EMC , state and local government Web resources and services. Real-time, global, sea surface temperature (RTG_SST_HR) analysis For a regional map, click the desired area in the global SST analysis and anomaly maps

Results of an Internet-Based Dual-Frequency Global Differential GPS System

NASA Technical Reports Server (NTRS)

Muellerschoen, R.; Bertiger, W.; Lough, M.

2000-01-01

Observables from a global network of 18 GPS receivers are returned in real-time to JPL over the open Internet. 30 - 40 cm RSS global GPS orbits and precise dual-frequency GPS clocks are computed in real-time with JPL's Real Time Gipsy (RTG) software.

The Spencer Research Training Grant at the Penn Graduate School of Education: Implementation and Effects

ERIC Educational Resources Information Center

Kecskemethy, Thomas A.

2008-01-01

Background/Context: The Research Training Grant (RTG) program at the University of Pennsylvania's Graduate School of Education aimed to create strong research training experiences for predissertation fellows through generous financial aid, mentored research apprenticeships, and cocurricular experiences. Collectively these offerings sought to…

Buried Object Classification using a Sediment Volume Imaging SAS and Electromagnetic Gradiometer

DTIC Science & Technology

2006-09-01

field data with simulated RTG data using AST’s in-house magnetic modeling tool EMAGINE . Given a set of input dipole moments, or pa- rameters to...approximate a moment by assuming the object is a prolate ellipsoid shell, EMAGINE uses Green’s func- tion formulations to generate three-component

The Impact of PERK on Posttraumatic Tauopathy in Alzheimer’s Disease

DTIC Science & Technology

2016-10-01

Complete imaging analyses (this work is completed continuously as injuries are performed) AIM2 4. Establish mouse cohorts for Aim 2 • rTg4510 transgenic ...animals to age to appropriate breeding age before we can perform any experiments. Changes that had a significant impact on expenditures No changes that

SNAP 19 Viking Program. Bimonthly technical progress report, February 1980-March 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-01-01

Viking 1 Lander power system data has not been available during this reporting period, but summary reports indicate no anomalies in performance. Monitoring and evaluation of Viking 2 Lander power system data continued. Temperature data were similar to those 23 months ago, but combined RTG output power was down by 7 watts from the 75 watts recorded in February of 1978. On February 7, 1980, during a scheduled relay transmission the Lander 2 battery voltage dropped below 26.5 volts. With the orbiter attitude control gas supply nearly depleted and the space network stations required for Voyager encounter with Saturn latermore » this year, the final relay from Viking Lander 2 had been scheduled to take place on April 11. The attempt was made but no data were received. Power system performance data for Pioneer 10 and Pioneer Saturn (initially designated Pioneer 11) were monitored. The estimated RTG system net power was 115 watts for both, Pioneer 10 and Pioneer Saturn. The telemetry signal quality from Pioneer Saturn remains excellent. Pioneer 10, for the first time, shows a loss of signal strength.« less

Rewiring AMPK and mitochondrial retrograde signaling for metabolic control of aging and histone acetylation in respiratory-defective cells.

PubMed

Friis, R Magnus N; Glaves, John Paul; Huan, Tao; Li, Liang; Sykes, Brian D; Schultz, Michael C

2014-04-24

Abnormal respiratory metabolism plays a role in numerous human disorders. We find that regulation of overall histone acetylation is perturbed in respiratory-incompetent (ρ(0)) yeast. Because histone acetylation is highly sensitive to acetyl-coenzyme A (acetyl-CoA) availability, we sought interventions that suppress this ρ(0) phenotype through reprogramming metabolism. Nutritional intervention studies led to the discovery that genetic coactivation of the mitochondrion-to-nucleus retrograde (RTG) response and the AMPK (Snf1) pathway prevents abnormal histone deacetylation in ρ(0) cells. Metabolic profiling of signaling mutants uncovered links between chromatin-dependent phenotypes of ρ(0) cells and metabolism of ATP, acetyl-CoA, glutathione, branched-chain amino acids, and the storage carbohydrate trehalose. Importantly, RTG/AMPK activation reprograms energy metabolism to increase the supply of acetyl-CoA to lysine acetyltransferases and extend the chronological lifespan of ρ(0) cells. Our results strengthen the framework for rational design of nutrient supplementation schemes and drug-discovery initiatives aimed at mimicking the therapeutic benefits of dietary interventions. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

RANK/RANKL/OPG Signalization Implication in Periodontitis: New Evidence from a RANK Transgenic Mouse Model

PubMed Central

Sojod, Bouchra; Chateau, Danielle; Mueller, Christopher G.; Babajko, Sylvie; Berdal, Ariane; Lézot, Frédéric; Castaneda, Beatriz

2017-01-01

Periodontitis is based on a complex inflammatory over-response combined with possible genetic predisposition factors. The RANKL/RANK/OPG signaling pathway is implicated in bone resorption through its key function in osteoclast differentiation and activation, as well as in the inflammatory response. This central element of osteo-immunology has been suggested to be perturbed in several diseases, including periodontitis, as it is a predisposing factor for this disease. The aim of the present study was to validate this hypothesis using a transgenic mouse line, which over-expresses RANK (RTg) and develops a periodontitis-like phenotype at 5 months of age. RTg mice exhibited severe alveolar bone loss, an increased number of TRAP positive cells, and disorganization of periodontal ligaments. This phenotype was more pronounced in females. We also observed dental root resorption lacunas. Hyperplasia of the gingival epithelium, including Malassez epithelial rests, was visible as early as 25 days, preceding any other symptoms. These results demonstrate that perturbations of the RANKL/RANK/OPG system constitute a core element of periodontitis, and more globally, osteo-immune diseases. PMID:28596739

Space nuclear safety from a user's viewpoint

NASA Technical Reports Server (NTRS)

Campbell, R. W.

1985-01-01

The National Aeronautics and Space Administration (NASA) launched the Jet Propulsion Laboratory's (JPL) two Voyager spacecraft to Jupiter in 1977, each using three radioisotope thermoelectric generators (RTGs) supplied by the Department of Energy (DOE) for onboard electric power. In 1986 NASA will launch JPL's Galileo spacecraft to Jupiter equipped with two DOE supplied RTGs of an improved design. NASA and JPL are also responsible for obtaining a single RTG of this type from DOE and supplying it to the European Space Agency as part of its participation in the International Solar Polar Mission. As a result of these missions, JPL has been deeply involved in space nuclear safety as a user. This paper will give a brief review of the user contributions by JPL - and NASA in general - to the nuclear safety processes and relate them to the overall nuclear safety program necessary for the launch of an RTG. The two major safety areas requiring user support are the ground operations involving RTGs at the launch site and the failure modes and probabilities associated with launch accidents.

The Use of 2 Conditioning Programs and the Fitness Characteristics of Police Academy Cadets.

PubMed

Cocke, Charles; Dawes, Jay; Orr, Robin Marc

2016-11-01

 Police academy training must physically prepare cadets for the rigors of their occupational tasks to prevent injury and allow them to adequately perform their duties.  To compare the effects of 2 physical training programs on multiple fitness measures in police cadets.  Cohort study.  Police training academy.  We collected data from 70 male (age = 27.4 ± 5.9 years, body weight = 85.4 ± 11.8 kg) and 20 female (age = 30.5 ± 5.8 years, body weight = 62.8 ± 11.0 kg) police cadets and analyzed data from 61 male cadets (age = 27.5 ± 5.5 years, body weight = 87.7 ± 13.2 kg).  Participants completed one of two 6-month training programs. The randomized training group (RTG; n = 50), comprising 4 separate and sequential groups (n = 13, n = 11, n = 13, n = 13), completed a randomized training program that incorporated various strength and endurance exercises chosen on the day of training. The periodized group (PG; n = 11) completed a periodized training program that alternated specific phases of training.  Anthropometric fitness measures were body weight, fat mass, and lean body mass. Muscular and metabolic fitness measures were 1-repetition maximum bench press, push-up and sit-up repetitions performed in 1 minute, vertical jump, 300-m sprint, and 2.4-km run.  The RTG demonstrated improvements in all outcome measures between pretraining and posttraining; however, the improvements varied among the 4 individual RTGs. Conversely, the PG displayed improvements in only 3 outcome measures (push-ups, sit-ups, and 300-m sprint) but approached the level of significance set for this study (P < .01) in body weight, fat mass, and 1-repetition maximum bench press.  Regardless of format, physical training programs can improve the fitness of tactical athletes. In general, physical fitness measures appeared to improve more in the RTG than in the PG. However, this observation varied among groups, and injury rates were not compared.

Lethal and sublethal effects of marine sediment extracts on fish cells and chromosomes

NASA Astrophysics Data System (ADS)

Landolt, Marsha L.; Kocan, Richard M.

1984-03-01

The cost of conducting conventional chronic bioassays with every potentially toxic compound found in marine ecosystems is prohibitive; therefore short-term toxicity tests which can be used for rapid screening were developed. The tests employ cultured fish cells to measure lethal, sublethal or genotoxic effects of pure compounds and complex mixtures. The sensitivity of these tests has been proven under laboratory conditions; the following study used two of these tests, the anaphase aberration test and a cytotoxicity assay, under field conditions. Sediment was collected from 97 stations within Puget Sound, Washington. Serial washings of the sediment in methanol and dichloromethane yielded an organic extract which was dried, dissolved in DMSO and incubated as a series of dilutions with rainbow trout gonad (RTG-2) cells. The toxic effects of the extract were measured by examining the rate of cell proliferation and the percentage of damaged anaphase figures. Anaphase figures were considered to be abnormal if they exhibited non-disjunctions, chromosome fragments, or chromosome bridges. A second cell line (bluegill fry, BF-2) was also tested for cell proliferation and was included because, unlike the RTG-2 cell line, it contains little or no mixed function oxygenase activity. Of 97 stations tested, 35 showed no genotoxic activity, 42 showed high genotoxic activity (P≤.01) and the remainder were intermediate. Among the toxic sites were several deep water stations adjacent to municipal sewage outfalls and four urban waterways contaminated by industrial and municipal effluents. Extracts from areas that showed genotoxic effects also inhibited cell proliferation and were cytotoxic to RTG-2 cells. Few effects were noted in the MFO deficient BF-2 cells. Short term in vitro tests provide aquatic toxicologists with a versatile and cost effective tool for screening complex environments. Through these tests one can identify compounds or geographic regions that exhibit high cytotoxic or genotoxic potential.

Non-Cooled Power System for Venus Lander

NASA Technical Reports Server (NTRS)

Salazar, Denise; Landis, Geoffrey A.; Colozza, Anthony J.

2014-01-01

The Planetary Science Decadal Survey of 2013-2022 stated that the exploration of Venus is of significant interest. Studying the seismic activity of the planet is of particular importance because the findings can be compared to the seismic activity of Earth. Further, the geological and atmospheric properties of Venus will shed light into the past and future of Earth. This paper presents a radioisotope power system (RPS) design for a small low-power Venus lander. The feasibility of the new power system is then compared to that of primary batteries. A requirement for the power source system is to avoid moving parts in order to not interfere with the primary objective of the mission - to collect data about the seismic activity of Venus using a seismometer. The target mission duration of the lander is 117 days, a significant leap from Venera 13, the longest-lived lander on the surface of Venus, which survived for 2 hours. One major assumption for this mission design is that the power source system will not provide cooling to the other components of the lander. This assumption is based on high-temperature electronics technology that will enable the electronics and components of the lander to operate at Venus surface temperature. For the proposed RPS, a customized General Purpose Heat Source Radioisotope Thermoelectric Generator (GPHSRTG) is designed and analyzed. The GPHS-RTG is chosen primarily because it has no moving parts and it is capable of operating for long duration missions on the order of years. This power system is modeled as a spherical structure for a fundamental thermal analysis. The total mass and electrical output of the system are calculated to be 24 kilograms and 26 Watts, respectively. An alternative design for a battery-based power system uses Sodium Sulfur batteries. To deliver a similar electrical output for 117 days, the battery mass is calculated to be 234 kilograms. Reducing mission duration or power required will reduce the required battery mass. Finally, the advantages and disadvantages of both power systems with regard to science return, risk, and cost are briefly compared. The design of the radioisotope power system is considerably riskier because it is novel and would require additional years of further refinement, manufacturing, safety analysis, and testing that the primary batteries do not need. However, the lifetime of the radioisotope power system makes its science return more promising.

Toward a Vibrant Research Community in Education: Investing in Early-Career Scholars

ERIC Educational Resources Information Center

Young, Lauren Jones

2008-01-01

Background/Context: In 1994, the Spencer Foundation embarked on an ambitious experimental initiative to support the preparation of education researchers. Over the 13-year span of the Research Training Grant (RTG) program, the foundation made multiyear awards to more than a dozen leading institutions in the United States and South Africa. This…

Exploring the Investment: Four Universities' Experiences with the Spencer Foundation's Research Training Grant Program--A Retrospective

ERIC Educational Resources Information Center

Neumann, Anna; Pallas, Aaron; Peterson, Penelope

2008-01-01

Background: This article serves as a conclusion to a TCR special issue devoted to understanding the impact of the Spencer Foundation's Research Training Grant (RTG) initiative. We examine four case reports prepared by scholars at the University of Wisconsin-Madison, the University of Pennsylvania, the University of California at Los Angeles…

Solar cell design for avoiding LILT degradation. [low intensity, low temperature

NASA Technical Reports Server (NTRS)

Stella, P. M.; Ctorry, G. T.

1987-01-01

Growing concerns about radioisotope thermoelectric generator (RTG) performance potential, cost, safety, and availability have renewed interest in utilizing photovoltaic energy conversion for future JPL interplanetary missions such as the Mariner Mark II set. Although lightweight solar array technology has advanced to the point where it would appear to provide an alternative power source, anomalous silicon cell curve shape degradation at conditions of low intensity and low temperature (LILT) severely restricts photovoltaic applications for missions beyond 3 AU solar distance. In order to extend photovoltaic applications to distances of 5 AU, ways to minimize the deleterious impact of LILT cell degradation were investigated. These investigations have ranged from consideration of individual cell selection for LILT behavior to the examination of methods for reducing or eliminating cell LILT degradation by modifying the cell processing. Use of a partial oxide barrier between the cell n+ contacts and the silicon has been shown to reduce significantly both the occurrence and magnitude of the LILT degradation.

[Uncommon foreign body in a nose].

PubMed

Alagić-Smailbegović, Jasminka; Hadzić, Edina; Sutalo, Kamenko; Resić, Mudzahid

2007-01-01

Foreign body in the nose most frequently occurs in childhood. It could be of various origin, pieces of toys, paper and uncommon metal body. Consequences include one- sided nasal breathing problem, nasal secretion and in some cases pain and secretion become purulent. The aim of this paper is to present uncommon foreign body in the nose. RTG diagnosis and extraction are the methods of choice.

Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy.

PubMed

Spires-Jones, Tara L; Friedman, Taylor; Pitstick, Rose; Polydoro, Manuela; Roe, Allyson; Carlson, George A; Hyman, Bradley T

2014-03-06

Alzheimer's disease is characterized pathologically by aggregation of amyloid beta into senile plaques and aggregation of pathologically modified tau into neurofibrillary tangles. While changes in amyloid processing are strongly implicated in disease initiation, the recent failure of amyloid-based therapies has highlighted the importance of tau as a therapeutic target. "Tangle busting" compounds including methylene blue and analogous molecules are currently being evaluated as therapeutics in Alzheimer's disease. Previous studies indicated that methylene blue can reverse tau aggregation in vitro after 10 min, and subsequent studies suggested that high levels of drug reduce tau protein levels (assessed biochemically) in vivo. Here, we tested whether methylene blue could remove established neurofibrillary tangles in the rTg4510 model of tauopathy, which develops robust tangle pathology. We find that 6 weeks of methylene blue dosing in the water from 16 months to 17.5 months of age decreases soluble tau but does not remove sarkosyl insoluble tau, or histologically defined PHF1 or Gallyas positive tangle pathology. These data indicate that methylene blue treatment will likely not rapidly reverse existing tangle pathology. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy

PubMed Central

Spires-Jones, Tara L; Friedman, Taylor; Pitstick, Rose; Polydoro, Manuela; Roe, Allyson; Carlson, George A; Hyman, Bradley T

2014-01-01

Alzheimer's disease is characterized pathologically by aggregation of amyloid beta into senile plaques and aggregation of pathologically modified tau into neurofibrillary tangles. While changes in amyloid processing are strongly implicated in disease initiation, the recent failure of amyloid-based therapies has highlighted the importance of tau as a therapeutic target. “Tangle busting” compounds including methylene blue and analogous molecules are currently being evaluated as therapeutics in Alzheimer's disease. Previous studies indicated that methylene blue can reverse tau aggregation in vitro after 10 minutes, and subsequent studies suggested that high levels of drug reduce tau protein levels (assessed biochemically) in vivo. Here, we tested whether methylene blue could remove established neurofibrillary tangles in the rTg4510 model of tauopathy, which develops robust tangle pathology. We find that 6 weeks of methylene blue dosing in the water from 16 months to 17.5 months of age decreases soluble tau but does not remove sarkosyl insoluble tau, or histologically defined PHF1 or Gallyas positive tangle pathology. These data indicate that methylene blue treatment will likely not rapidly reverse existing tangle pathology. PMID:24462887

Start-up Characteristics of Swallow-tailed Axial-grooved Heat Pipe under the conditions of Multiple Heat Sources

NASA Astrophysics Data System (ADS)

Zhang, Renping

2017-12-01

A mathematical model was developed for predicting start-up characteristics of Swallow-tailed Axial-grooved Heat Pipe under the conditions of Multiple Heat Sources. The effects of heat capacitance of heat source, liquid-vapour interfacial evaporation-condensation heat transfer, shear stress at the interface was considered in current model. The interfacial evaporating mass flow rate is based on the kinetic analysis. Time variations of evaporating mass rate, wall temperature and liquid velocity are studied from the start-up to steady state. The calculated results show that wall temperature demonstrates step transition at the junction between the heat source and non-existent heat source on the evaporator. The liquid velocity changes drastically at the evaporator section, however, it has slight variation at the evaporator section without heat source. When the effect of heat source is ignored, the numerical temperature demonstrates a quicker response. With the consideration of capacitance of the heat source, the data obtained from the proposed model agree well with the experimental results.

Loop Heat Pipe Operation Using Heat Source Temperature for Set Point Control

NASA Technical Reports Server (NTRS)

Ku, Jentung; Paiva, Kleber; Mantelli, Marcia

2011-01-01

The LHP operating temperature is governed by the saturation temperature of its reservoir. Controlling the reservoir saturation temperature is commonly accomplished by cold biasing the reservoir and using electrical heaters to provide the required control power. Using this method, the loop operating temperature can be controlled within +/- 0.5K. However, because of the thermal resistance that exists between the heat source and the LHP evaporator, the heat source temperature will vary with its heat output even if LHP operating temperature is kept constant. Since maintaining a constant heat source temperature is of most interest, a question often raised is whether the heat source temperature can be used for LHP set point temperature control. A test program with a miniature LHP has been carried out to investigate the effects on the LHP operation when the control temperature sensor is placed on the heat source instead of the reservoir. In these tests, the LHP reservoir is cold-biased and is heated by a control heater. Tests results show that it is feasible to use the heat source temperature for feedback control of the LHP operation. Using this method, the heat source temperature can be maintained within a tight range for moderate and high powers. At low powers, however, temperature oscillations may occur due to interactions among the reservoir control heater power, the heat source mass, and the heat output from the heat source. In addition, the heat source temperature could temporarily deviate from its set point during fast thermal transients. The implication is that more sophisticated feedback control algorithms need to be implemented for LHP transient operation when the heat source temperature is used for feedback control.

Near-chip compliant layer for reducing perimeter stress during assembly process

DOEpatents

Schultz, Mark D.; Takken, Todd E.; Tian, Shurong; Yao, Yuan

2018-03-20

A heat source (single semiconductor chip or group of closely spaced semiconductor chips of similar height) is provided on a first side of a substrate, which substrate has on said first side a support member comprising a compressible material. A heat removal component, oriented at an angle to said heat source, is brought into proximity of said heat source such that said heat removal component contacts said support member prior to contacting said heat source. Said heat removal component is assembled to said heat source such that said support member at least partially absorbs global inequality of force that would otherwise be applied to said heat source, absent said support member comprising said compressible material.

Near-chip compliant layer for reducing perimeter stress during assembly process

DOEpatents

Schultz, Mark D.; Takken, Todd E.; Tian, Shurong; Yao, Yuan

2017-02-14

A heat source (single semiconductor chip or group of closely spaced semiconductor chips of similar height) is provided on a first side of a substrate, which substrate has on said first side a support member comprising a compressible material. A heat removal component, oriented at an angle to said heat source, is brought into proximity of said heat source such that said heat removal component contacts said support member prior to contacting said heat source. Said heat removal component is assembled to said heat source such that said support member at least partially absorbs global inequality of force that would otherwise be applied to said heat source, absent said support member comprising said compressible material.

Thermal Conductivity of Single-Walled Carbon Nanotube with Internal Heat Source Studied by Molecular Dynamics Simulation

NASA Astrophysics Data System (ADS)

Li, Yuan-Wei; Cao, Bing-Yang

2013-12-01

The thermal conductivity of (5, 5) single-walled carbon nanotubes (SWNTs) with an internal heat source is investigated by using nonequilibrium molecular dynamics (NEMD) simulation incorporating uniform heat source and heat source-and-sink schemes. Compared with SWNTs without an internal heat source, i.e., by a fixed-temperature difference scheme, the thermal conductivity of SWNTs with an internal heat source is much lower, by as much as half in some cases, though it still increases with an increase of the tube length. Based on the theory of phonon dynamics, a function called the phonon free path distribution is defined to develop a simple one-dimensional heat conduction model considering an internal heat source, which can explain diffusive-ballistic heat transport in carbon nanotubes well.

Impact of Lake Okeechobee Sea Surface Temperatures on Numerical Predictions of Summertime Convective Systems over South Florida

NASA Technical Reports Server (NTRS)

Case, Jonathan L.; Splitt, Michael E.; Fuell, Kevin K.; Santos, Pablo; Lazarus, Steven M.; Jedlovec, Gary J.

2009-01-01

The NASA Short-term Prediction Research and Transition (SPoRT) Center, the Florida Institute of Technology, and the NOAA/NWS Weather Forecast Office at Miami, FL (MFL) are collaborating on a project to investigate the impact of using high-resolution, 2-km Moderate Resolution Imaging Spectroradiometer (MODIS) sea surface temperature (SST) composites within the Weather Research and Forecasting (WRF) prediction system. The NWS MFL is currently running WRF in real-time to support daily forecast operations, using the National Centers for Environmental Prediction Nonhydrostatic Mesoscale Model dynamical core within the NWS Science and Training Resource Center's Environmental Modeling System (EMS) software. Twenty-seven hour forecasts are run daily initialized at 0300, 0900, 1500, and 2100 UTC on a domain with 4-km grid spacing covering the southern half of Florida and adjacent waters of the Gulf of Mexico and Atlantic Ocean. The SSTs are initialized with the NCEP Real-Time Global (RTG) analyses at 1/12deg resolution. The project objective is to determine whether more accurate specification of the lower-boundary forcing over water using the MODIS SST composites within the 4-km WRF runs will result in improved sea fluxes and hence, more accurate e\\olutiono f coastal mesoscale circulations and the associated sensible weather elements. SPoRT conducted parallel WRF EMS runs from February to August 2007 identical to the operational runs at NWS MFL except for the use of MODIS SST composites in place of the RTG product as the initial and boundary conditions over water. During the course of this evaluation, an intriguing case was examined from 6 May 2007, in which lake breezes and convection around Lake Okeechobee evolved quite differently when using the high-resolution SPoRT MODIS SST composites versus the lower-resolution RTG SSTs. This paper will analyze the differences in the 6 May simulations, as well as examine other cases from the summer 2007 in which the WRF-simulated Lake Okeechobee breezes evolved differently due to the SST initialization. The effects on wind fields and precipitation systems will be emphasized, including validation against surface mesonet observations and Stage IV precipitation grids.

Variable pressure power cycle and control system

DOEpatents

Goldsberry, Fred L.

1984-11-27

A variable pressure power cycle and control system that is adjustable to a variable heat source is disclosed. The power cycle adjusts itself to the heat source so that a minimal temperature difference is maintained between the heat source fluid and the power cycle working fluid, thereby substantially matching the thermodynamic envelope of the power cycle to the thermodynamic envelope of the heat source. Adjustments are made by sensing the inlet temperature of the heat source fluid and then setting a superheated vapor temperature and pressure to achieve a minimum temperature difference between the heat source fluid and the working fluid.

Vibration Testing of the Pluto/New Horizons Radioisotope Thermoelectric Generator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Charles D. Griffin

The Radioisotopic Thermal Generator (RTG) for the Pluto/New Horizons spacecraft was subjected to a flight dynamic acceptance test to demonstrate that it would perform successfully following launch. Seven RTGs of this type had been assembled and tested at Mound, Ohio from 1984 to 1997. This paper chronicles major events in establishing a new vibration test laboratory at the Idaho National Laboratory and the nineteen days of dynamic testing.

Development of advanced thermoelectric materials

NASA Technical Reports Server (NTRS)

1984-01-01

The development of an advanced thermoelectric material for radioisotope thermoelectric generator (RTG) applications is reported. A number of materials were explored. The bulk of the effort, however, was devoted to improving silicon germanium alloys by the addition of gallium phosphide, the synthesis and evaluation of lanthanum chrome sulfide and the formulation of various mixtures of lanthanum sulfide and chrome sulfide. It is found that each of these materials exhibits promise as a thermoelectric material.

GPHS-RTGs in support of the Cassini Mission

NASA Astrophysics Data System (ADS)

1994-10-01

The progress on the radioisotope generators and ancillary activities is described. This report is organized by program task as follows: spacecraft integration and liaison; engineering support; safety; qualified unicouple fabrication; ETG fabrication, assembly, and test; ground support equipment; RTG shipping and launch support; design, reviews, and mission applications; project management, quality assurance and reliability, contract changes, non-capital CAGO acquisition, and CAGO maintenance; contractor acquired government owned property (CAGO) acquisition.

GPHS-RTGs in support of the Cassini mission

NASA Astrophysics Data System (ADS)

1992-04-01

The technical progress achieved during the period 30 Mar. - 27 Sep. 1992 is described. Topics covered include: spacecraft integration and liaison; engineering support; safety; qualified unicouple production, ETG fabrication, assembly, and test; ground support equipment; radioisotope thermoelectric generators (RTG) shipping and launch support; designs, reviews, and mission applications; project management, quality assurance, reliability, contract changes, non-capital contractor acquired government owned (CAGO) acquisitions, and CAGO maintenance; and CAGO acquisitions.

Bone structure regeneration after low induction magnetic field treatment in teeth chosen for extraction.

PubMed

Opalko, K; Dojs, A

2006-01-01

The aim of the work was to use and to evaluate the usefulness of the slow variable magnetic fields to aid the treatment of the teeth chosen for extraction. The marginal paradontium of periapical bone of teeth was in a state of extensive destruction. The teeth were chosen for extraction. 13 patients were chosen. 10 of them had with endo-perio changes and 3 suffered from full tooth luxation and had the teeth replanted. Those people were to have an extraction procedure or were declared as impossible to treat in other dental offices. Patients underwent non-aggressive skaling, endodontic treatment and were exposed to slow variable magnetic fields generated by Viofor JPS, accordingly to methods and parameters suggested by Department of Propaedeutics in Dentistry of Pomeranian Medical University in Szczecin. The process of healing of changes was evaluated radiologically. RTG done after 2 weeks and after 2 months were evaluated in respect of bone regeneration. They show the bone structure concentration. A RTG evaluation after half a year, two and three years show a preservation of the bone structure concentration. The use of slow variable magnetic fields contributed to bone structure regeneration and to preserve teeth with recorded endo-perio syndrome. Endodontic treatment of replanted teeth, aided with magnetostimulation has stopped the osteolisis process.

Carbothermic reduction with parallel heat sources

DOEpatents

Troup, Robert L.; Stevenson, David T.

1984-12-04

Disclosed are apparatus and method of carbothermic direct reduction for producing an aluminum alloy from a raw material mix including aluminum oxide, silicon oxide, and carbon wherein parallel heat sources are provided by a combustion heat source and by an electrical heat source at essentially the same position in the reactor, e.g., such as at the same horizontal level in the path of a gravity-fed moving bed in a vertical reactor. The present invention includes providing at least 79% of the heat energy required in the process by the electrical heat source.

Loop Heat Pipe Operation Using Heat Source Temperature for Set Point Control

NASA Technical Reports Server (NTRS)

Ku, Jentung; Paiva, Kleber; Mantelli, Marcia

2011-01-01

Loop heat pipes (LHPs) have been used for thermal control of several NASA and commercial orbiting spacecraft. The LHP operating temperature is governed by the saturation temperature of its compensation chamber (CC). Most LHPs use the CC temperature for feedback control of its operating temperature. There exists a thermal resistance between the heat source to be cooled by the LHP and the LHP's CC. Even if the CC set point temperature is controlled precisely, the heat source temperature will still vary with its heat output. For most applications, controlling the heat source temperature is of most interest. A logical question to ask is: "Can the heat source temperature be used for feedback control of the LHP operation?" A test program has been implemented to answer the above question. Objective is to investigate the LHP performance using the CC temperature and the heat source temperature for feedback control

Hydride compressor

DOEpatents

Powell, James R.; Salzano, Francis J.

1978-01-01

Method of producing high energy pressurized gas working fluid power from a low energy, low temperature heat source, wherein the compression energy is gained by using the low energy heat source to desorb hydrogen gas from a metal hydride bed and the desorbed hydrogen for producing power is recycled to the bed, where it is re-adsorbed, with the recycling being powered by the low energy heat source. In one embodiment, the adsorption-desorption cycle provides a chemical compressor that is powered by the low energy heat source, and the compressor is connected to a regenerative gas turbine having a high energy, high temperature heat source with the recycling being powered by the low energy heat source.

Dual source heat pump

DOEpatents

Ecker, Amir L.; Pietsch, Joseph A.

1982-01-01

What is disclosed is a heat pump apparatus for conditioning a fluid characterized by a fluid handler and path for circulating the fluid in heat exchange relationship with a refrigerant fluid; at least two refrigerant heat exchangers, one for effecting heat exchange with the fluid and a second for effecting heat exchange between refrigerant and a heat exchange fluid and the ambient air; a compressor for efficiently compressing the refrigerant; at least one throttling valve for throttling liquid refrigerant; a refrigerant circuit; refrigerant; a source of heat exchange fluid; heat exchange fluid circulating device and heat exchange fluid circuit for circulating the heat exchange fluid in heat exchange relationship with the refrigerant; and valves or switches for selecting the heat exchangers and direction of flow of the refrigerant therethrough for selecting a particular mode of operation. The heat exchange fluid provides energy for defrosting the second heat exchanger when operating in the air source mode and also provides a alternate source of heat.

30 CFR 56.4500 - Heat sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Heat sources. 56.4500 Section 56.4500 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Installation/construction/maintenance § 56.4500 Heat sources. Heat sources capable of producing combustion...

30 CFR 57.4500 - Heat sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Heat sources. 57.4500 Section 57.4500 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Installation/construction/maintenance § 57.4500 Heat sources. Heat sources capable of producing combustion...

30 CFR 57.4500 - Heat sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Heat sources. 57.4500 Section 57.4500 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Installation/construction/maintenance § 57.4500 Heat sources. Heat sources capable of producing combustion...

30 CFR 57.4500 - Heat sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Heat sources. 57.4500 Section 57.4500 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Installation/construction/maintenance § 57.4500 Heat sources. Heat sources capable of producing combustion...

30 CFR 56.4500 - Heat sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Heat sources. 56.4500 Section 56.4500 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Installation/construction/maintenance § 56.4500 Heat sources. Heat sources capable of producing combustion...

30 CFR 56.4500 - Heat sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Heat sources. 56.4500 Section 56.4500 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Installation/construction/maintenance § 56.4500 Heat sources. Heat sources capable of producing combustion...

30 CFR 57.4500 - Heat sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Heat sources. 57.4500 Section 57.4500 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Installation/construction/maintenance § 57.4500 Heat sources. Heat sources capable of producing combustion...

30 CFR 56.4500 - Heat sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Heat sources. 56.4500 Section 56.4500 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Installation/construction/maintenance § 56.4500 Heat sources. Heat sources capable of producing combustion...

Passive rejection of heat from an isotope heat source through an open door

NASA Technical Reports Server (NTRS)

Burns, R. K.

1971-01-01

The isotope heat-source design for a Brayton power system includes a door in the thermal insulation through which the heat can be passively rejected to space when the power system is not operating. The results of an analysis to predict the heat-source surface temperature and the heat-source heat-exchanger temperature during passive heat rejection as a function of insulation door opening angle are presented. They show that for a door opening angle greater than 20 deg, the temperatures are less than the steady-state temperatures during power system operation.

Mini-Brayton heat source assembly design study. Volume 2: Titan 3C mission. [minimum weight modifications

NASA Technical Reports Server (NTRS)

1973-01-01

Major conclusions of the space shuttle heat source assembly study are reported that project a minimum weight design for a Titan 3 C synchronous orbit mission; requirements to recover the heat source in orbit are eliminated. This concept permits location of the heat source end enclosure supports and heat source assembly support housing in a low temperature region external to the insulation enclosure and considers titanium and beryllium alloys for these support elements. A high melting insulation blanket consisting of nickel foil coated with zirconia, or of gold foil separated with glass fiber layers, is selected to provide emergency cooling in the range 2000 to 2700 F to prevent the isotope heat source from reaching unsafe temperatures. A graphic view of the baseline heat source assembly is included.

Base flow investigation of the Apollo AS-202 Command Module

NASA Astrophysics Data System (ADS)

Walpot, Louis M. G.; Wright, Michael J.; Noeding, Peter; Schrijer, Ferry

2012-01-01

A major contributor to the overall vehicle mass of re-entry vehicles is the afterbody thermal protection system. This is due to the large acreage (equal or bigger than that of the forebody) to be protected. The present predictive capabilities for base flows are comparatively lower than those for windward flowfields and offer therefore a substantial potential for improving the design of future re-entry vehicles. To that end, it is essential to address the accuracy of high fidelity CFD tools exercised in the US and EU, which motivates a thorough investigation of the present status of hypersonic flight afterbody heating. This paper addresses the predictive capabilities of afterbody flow fields of re-entry vehicles investigated in the frame of the NATO/RTO-RTG-043 task group. First, the verification of base flow topologies on the basis of available wind-tunnel results performed under controlled supersonic conditions (i.e. cold flows devoid of reactive effects) is performed. Such tests address the detailed characterization of the base flow with particular emphasis on separation/reattachment and their relation to Mach number effects. The tests have been performed on an Apollo-like re-entry capsule configuration. Second, the tools validated in the frame of the previous effort are exercised and appraised against flight-test data collected during the Apollo AS-202 re-entry.

Thermal Interface Evaluation of Heat Transfer from a Pumped Loop to Titanium-Water Thermosyphons

NASA Technical Reports Server (NTRS)

Jaworske, Donald A.; Sanzi, James L.; Gibson, Marc A.; Sechkar, Edward A.

2009-01-01

Titanium-water thermosyphons are being considered for use in the heat rejection system for lunar outpost fission surface power. Key to their use is heat transfer between a closed loop heat source and the heat pipe evaporators. This work describes laboratory testing of several interfaces that were evaluated for their thermal performance characteristics, in the temperature range of 350 to 400 K, utilizing a water closed loop heat source and multiple thermosyphon evaporator geometries. A gas gap calorimeter was used to measure heat flow at steady state. Thermocouples in the closed loop heat source and on the evaporator were used to measure thermal conductance. The interfaces were in two generic categories, those immersed in the water closed loop heat source and those clamped to the water closed loop heat source with differing thermal conductive agents. In general, immersed evaporators showed better overall performance than their clamped counterparts. Selected clamped evaporator geometries offered promise.

Safe atmosphere entry of an isotope heat source with a single stable trim attitude at hypersonic speeds

NASA Technical Reports Server (NTRS)

Levy, L. L., Jr.; Burns, R. K.

1972-01-01

A theoretical investigation has been made to design an isotope heat source capable of satisfying the conflicting thermal requirements of steady-state operation and atmosphere entry. The isotope heat source must transfer heat efficiently to a heat exchange during normal operation with a power system in space, and in the event of a mission abort, it must survive the thermal environment of atmosphere entry and ground impact without releasing radioactive material. A successful design requires a compatible integration of the internal components of the heat source with the external aerodynamic shape. To this end, configurational, aerodynamic, motion, and thermal analyses were coupled and iterated during atmosphere entries at suborbital through superorbital velocities at very shallow and very steep entry angles. Results indicate that both thermal requirements can be satisfied by a heat source which has a single stable aerodynamic orientation at hypersonic speeds. For such a design, the insulation material required to adequately protect the isotope fuel from entry heating need extend only half way around the fuel capsule on the aerodynamically stable (wind-ward) side of the heat source. Thus, a low-thermal-resistance, conducting heat path is provided on the opposite side of the heat source through which heat can be transferred to an adjacent heat exchanger during normal operation without exceeding specified temperature limits.

21 CFR 872.6475 - Heat source for bleaching teeth.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Heat source for bleaching teeth. 872.6475 Section... (CONTINUED) MEDICAL DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6475 Heat source for bleaching teeth. (a) Identification. A heat source for bleaching teeth is an AC-powered device that consists of a...

21 CFR 872.6475 - Heat source for bleaching teeth.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Heat source for bleaching teeth. 872.6475 Section... (CONTINUED) MEDICAL DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6475 Heat source for bleaching teeth. (a) Identification. A heat source for bleaching teeth is an AC-powered device that consists of a...

21 CFR 872.6475 - Heat source for bleaching teeth.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Heat source for bleaching teeth. 872.6475 Section... (CONTINUED) MEDICAL DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6475 Heat source for bleaching teeth. (a) Identification. A heat source for bleaching teeth is an AC-powered device that consists of a...

21 CFR 872.6475 - Heat source for bleaching teeth.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Heat source for bleaching teeth. 872.6475 Section... (CONTINUED) MEDICAL DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6475 Heat source for bleaching teeth. (a) Identification. A heat source for bleaching teeth is an AC-powered device that consists of a...

21 CFR 872.6475 - Heat source for bleaching teeth.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Heat source for bleaching teeth. 872.6475 Section... (CONTINUED) MEDICAL DEVICES DENTAL DEVICES Miscellaneous Devices § 872.6475 Heat source for bleaching teeth. (a) Identification. A heat source for bleaching teeth is an AC-powered device that consists of a...

A capital cost comparison of commercial ground-source heat pump systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rafferty, K.

1994-06-01

The purpose of the report is to compare capital costs associated with the three designs of ground source heat pumps. Specifically, the costs considered are those associated with the heat source/heat sink or ground source portion of the system. In order to standardize the heat rejection over the three designs, it was assumed that the heat pump loop would operate at a temperature range of 85{degree} (to the heat pumps) to 95{degree} (from the heat pumps) under peak conditions. The assumption of constant loop temperature conditions for all three permits an apples-to-apples comparison of the alternatives.

The Role of AhR in Breast Cancer Development

DTIC Science & Technology

2004-07-01

The renilla luciferase vectorphRL-TK (0.05 rtg) was co-transfected with firefly luciferase reporter constructs (0.1 ptg pGudLuc, 0.5-1.0 [tg wildtype...Glo Luciferase system (Promega, Madison, WI ) which allowed sequential reading of the firefly and renilla signals. Cells were lysed according to the...Madison, WI ). The renilla signal was read after quenching the firefly output, thus allowing normalization between sample wells. The normalized firefly

NEPP Update of Independent Single Event Upset Field Programmable Gate Array Testing

NASA Technical Reports Server (NTRS)

Berg, Melanie; Label, Kenneth; Campola, Michael; Pellish, Jonathan

2017-01-01

This presentation provides a NASA Electronic Parts and Packaging (NEPP) Program update of independent Single Event Upset (SEU) Field Programmable Gate Array (FPGA) testing including FPGA test guidelines, Microsemi RTG4 heavy-ion results, Xilinx Kintex-UltraScale heavy-ion results, Xilinx UltraScale+ single event effect (SEE) test plans, development of a new methodology for characterizing SEU system response, and NEPP involvement with FPGA security and trust.

Front End Analysis of Soldier Individual Power Systems

DTIC Science & Technology

1993-05-01

in the state-of-the-art MOD-GPHS-RTG, but with the fuel being polonium 210 , with a half life of 13.1.4 days, in the form of a gadolinium polonide (GdPo...allies, and industry to evaluate state-of-the-art technologies and integrate them into a system with synergistic improvement in combat effectiveness . The...Schemes ................................................... 79 Front End Analysis of Soldier Individual Power S LIST OF FIGURES I Effect of Mission

GPHS-RTGs in support of the Cassini mission

NASA Astrophysics Data System (ADS)

1994-04-01

This report is organized by the program task structure as follows: (1) spacecraft integration and liaison; (2) engineering support; (3) safety; (4) qualified unicouple fabrication; (5) ETG fabrication, assembly, and test; (6) ground support equipment (GSE); (7) RTG shipping and launch support; (8) designs, reviews, and mission applications; (9) project management, quality assurance and reliability, contract changes, noncapital contractor acquired government owned property (CAGO) acquisition, and CAGO maintenance; and (10) CAGO acquisition.

Solar heating and cooling: Technical data and systems analysis

NASA Technical Reports Server (NTRS)

Christensen, D. L.

1975-01-01

The solar energy research is reported including climatic data, architectural data, heating and cooling equipment, thermal loads, and economic data. Lists of data sources presented include: selected data sources for solar energy heating and cooling; bibliography of solar energy, and other energy sources; sources for manufacturing and sales, solar energy collectors; and solar energy heating and cooling projects.

Heat pump system

DOEpatents

Swenson, Paul F.; Moore, Paul B.

1979-01-01

An air heating and cooling system for a building includes an expansion-type refrigeration circuit and a heat engine. The refrigeration circuit includes two heat exchangers, one of which is communicated with a source of indoor air from the building and the other of which is communicated with a source of air from outside the building. The heat engine includes a heat rejection circuit having a source of rejected heat and a primary heat exchanger connected to the source of rejected heat. The heat rejection circuit also includes an evaporator in heat exchange relation with the primary heat exchanger, a heat engine indoor heat exchanger, and a heat engine outdoor heat exchanger. The indoor heat exchangers are disposed in series air flow relationship, with the heat engine indoor heat exchanger being disposed downstream from the refrigeration circuit indoor heat exchanger. The outdoor heat exchangers are also disposed in series air flow relationship, with the heat engine outdoor heat exchanger disposed downstream from the refrigeration circuit outdoor heat exchanger. A common fluid is used in both of the indoor heat exchangers and in both of the outdoor heat exchangers. In a first embodiment, the heat engine is a Rankine cycle engine. In a second embodiment, the heat engine is a non-Rankine cycle engine.

Heat pump system

DOEpatents

Swenson, Paul F.; Moore, Paul B.

1982-01-01

An air heating and cooling system for a building includes an expansion-type refrigeration circuit and a heat engine. The refrigeration circuit includes two heat exchangers, one of which is communicated with a source of indoor air from the building and the other of which is communicated with a source of air from outside the building. The heat engine includes a heat rejection circuit having a source of rejected heat and a primary heat exchanger connected to the source of rejected heat. The heat rejection circuit also includes an evaporator in heat exchange relation with the primary heat exchanger, a heat engine indoor heat exchanger, and a heat engine outdoor heat exchanger. The indoor heat exchangers are disposed in series air flow relationship, with the heat engine indoor heat exchanger being disposed downstream from the refrigeration circuit indoor heat exchanger. The outdoor heat exchangers are also disposed in series air flow relationship, with the heat engine outdoor heat exchanger disposed downstream from the refrigeration circuit outdoor heat exchanger. A common fluid is used in both of the indoor heat exchanges and in both of the outdoor heat exchangers. In a first embodiment, the heat engine is a Rankine cycle engine. In a second embodiment, the heat engine is a non-Rankine cycle engine.

Heat source reconstruction from noisy temperature fields using an optimised derivative Gaussian filter

NASA Astrophysics Data System (ADS)

Delpueyo, D.; Balandraud, X.; Grédiac, M.

2013-09-01

The aim of this paper is to present a post-processing technique based on a derivative Gaussian filter to reconstruct heat source fields from temperature fields measured by infrared thermography. Heat sources can be deduced from temperature variations thanks to the heat diffusion equation. Filtering and differentiating are key-issues which are closely related here because the temperature fields which are processed are unavoidably noisy. We focus here only on the diffusion term because it is the most difficult term to estimate in the procedure, the reason being that it involves spatial second derivatives (a Laplacian for isotropic materials). This quantity can be reasonably estimated using a convolution of the temperature variation fields with second derivatives of a Gaussian function. The study is first based on synthetic temperature variation fields corrupted by added noise. The filter is optimised in order to reconstruct at best the heat source fields. The influence of both the dimension and the level of a localised heat source is discussed. Obtained results are also compared with another type of processing based on an averaging filter. The second part of this study presents an application to experimental temperature fields measured with an infrared camera on a thin plate in aluminium alloy. Heat sources are generated with an electric heating patch glued on the specimen surface. Heat source fields reconstructed from measured temperature fields are compared with the imposed heat sources. Obtained results illustrate the relevancy of the derivative Gaussian filter to reliably extract heat sources from noisy temperature fields for the experimental thermomechanics of materials.

Loop Heat Pipe Transient Behavior Using Heat Source Temperature for Set Point Control with Thermoelectric Converter on Reservoir

NASA Technical Reports Server (NTRS)

Ku, Jentung; Paiva, Kleber; Mantelli, Marcia

2011-01-01

The LHP operating temperature is governed by the saturation temperature of its reservoir. Controlling the reservoir saturation temperature is commonly done by cold biasing the reservoir and using electrical heaters to provide the required control power. With this method, the loop operating temperature can be controlled within 0.5K or better. However, because the thermal resistance that exists between the heat source and the LHP evaporator, the heat source temperature will vary with its heat output even if the LHP operating temperature is kept constant. Since maintaining a constant heat source temperature is of most interest, a question often raised is whether the heat source temperature can be used for LHP set point temperature control. A test program with a miniature LHP was carried out to investigate the effects on the LHP operation when the control temperature sensor was placed on the heat source instead of the reservoir. In these tests, the LHP reservoir was cold-biased and was heated by a control heater. Test results show that it was feasible to use the heat source temperature for feedback control of the LHP operation. In particular, when a thermoelectric converter was used as the reservoir control heater, the heat source temperature could be maintained within a tight range using a proportional-integral-derivative or on/off control algorithm. Moreover, because the TEC could provide both heating and cooling to the reservoir, temperature oscillations during fast transients such as loop startup could be eliminated or substantially reduced when compared to using an electrical heater as the control heater.

Energy saving analysis on mine-water source heat pump in a residential district of Henan province, central China

NASA Astrophysics Data System (ADS)

Wang, Hong; Duan, Huanlin; Chen, Aidong

2018-02-01

In this paper, the mine-water source heat pump system is proposed in residential buildings of a mining community. The coefficient of performance (COP) and the efficiency of exergy are analyzed. The results show that the COP and exergy efficiency of the mine-water source heat pump are improved, the exergy efficiency of mine-water source heat pump is more than 10% higher than that of the air source heat pump.The electric power conservation measure of “peak load shifting” is also emphasized in this article. It shows that itis a very considerable cost in the electric saving by adopting the trough period electricity to produce hot water. Due to the proper temperature of mine water, the mine-watersource heat pump unit is more efficient and stable in performance, which further shows the advantage of mine-water source heat pump in energy saving and environmental protection. It provides reference to the design of similar heat pump system as well.

Parallel-plate heat pipe apparatus having a shaped wick structure

DOEpatents

Rightley, Michael J.; Adkins, Douglas R.; Mulhall, James J.; Robino, Charles V.; Reece, Mark; Smith, Paul M.; Tigges, Chris P.

2004-12-07

A parallel-plate heat pipe is disclosed that utilizes a plurality of evaporator regions at locations where heat sources (e.g. semiconductor chips) are to be provided. A plurality of curvilinear capillary grooves are formed on one or both major inner surfaces of the heat pipe to provide an independent flow of a liquid working fluid to the evaporator regions to optimize heat removal from different-size heat sources and to mitigate the possibility of heat-source shadowing. The parallel-plate heat pipe has applications for heat removal from high-density microelectronics and laptop computers.

Convective heat transfer in a porous enclosure saturated by nanofluid with different heat sources

NASA Astrophysics Data System (ADS)

Muthtamilselvan, M.; Sureshkumar, S.

2018-03-01

The present study is proposed to investigate the effects of various lengths and different locations of the heater on the left sidewall in a square lid-driven porous cavity filled with nanofluid. A higher temperature is maintained on the left wall where three different lengths and three different locations of the heat source are considered for the analysis. The right wall is kept at a lower temperature while the top and bottom walls, and the remaining portions of the heated wall are adiabatic. The governing equations are solved by finite volume method. The results show that among the different lengths of the heat source, an enhancement in the heat transfer rate is observed only for the length LH = 1/3 of the heat source. In the case of location of the heat source, the overall heat transfer rate is increased when the heat source is located at the top of the hot wall. For Ri = 1 and 0.01, a better heat transfer rate is obtained when the heat source is placed at the top of the hot wall whereas for Ri = 100, it occurs when the heating portion is at the middle of the hot wall. As the solid volume fraction increases, the viscosity of the fluid is increased, which causes a reduction in the flow intensity. An addition of nanoparticles in the base fluid enhances the overall heat transfer rate significantly for all Da considered. The permeability of the porous medium plays a major role in convection of nanofluid than porosity. A high heat transfer rate (57.26%) is attained for Da = 10-1 and χ = 0.06.

Computational inverse methods of heat source in fatigue damage problems

NASA Astrophysics Data System (ADS)

Chen, Aizhou; Li, Yuan; Yan, Bo

2018-04-01

Fatigue dissipation energy is the research focus in field of fatigue damage at present. It is a new idea to solve the problem of calculating fatigue dissipation energy by introducing inverse method of heat source into parameter identification of fatigue dissipation energy model. This paper introduces the research advances on computational inverse method of heat source and regularization technique to solve inverse problem, as well as the existing heat source solution method in fatigue process, prospects inverse method of heat source applying in fatigue damage field, lays the foundation for further improving the effectiveness of fatigue dissipation energy rapid prediction.

Radioisotopic heat source

DOEpatents

Sayell, E.H.

1973-10-23

A radioisotopic heat source is described which includes a core of heat productive, radioisotopic material, an impact resistant layer of graphite surrounding said core, and a shell of iridium metal intermediate the core and the impact layer. The source may also include a compliant mat of iridium between the core and the iridium shell, as well as an outer covering of iridium metal about the entire heat source. (Official Gazette)

Optimum load distribution between heat sources based on the Cournot model

NASA Astrophysics Data System (ADS)

Penkovskii, A. V.; Stennikov, V. A.; Khamisov, O. V.

2015-08-01

One of the widespread models of the heat supply of consumers, which is represented in the "Single buyer" format, is considered. The methodological base proposed for its description and investigation presents the use of principles of the theory of games, basic propositions of microeconomics, and models and methods of the theory of hydraulic circuits. The original mathematical model of the heat supply system operating under conditions of the "Single buyer" organizational structure provides the derivation of a solution satisfying the market Nash equilibrium. The distinctive feature of the developed mathematical model is that, along with problems solved traditionally within the bounds of bilateral relations of heat energy sources-heat consumer, it considers a network component with its inherent physicotechnical properties of the heat network and business factors connected with costs of the production and transportation of heat energy. This approach gives the possibility to determine optimum levels of load of heat energy sources. These levels provide the given heat energy demand of consumers subject to the maximum profit earning of heat energy sources and the fulfillment of conditions for formation of minimum heat network costs for a specified time. The practical realization of the search of market equilibrium is considered by the example of a heat supply system with two heat energy sources operating on integrated heat networks. The mathematical approach to the solution search is represented in the graphical form and illustrates computations based on the stepwise iteration procedure for optimization of levels of loading of heat energy sources (groping procedure by Cournot) with the corresponding computation of the heat energy price for consumers.

Heating device for semiconductor wafers

DOEpatents

Vosen, Steven R.

1999-01-01

An apparatus for heat treating semiconductor wafers is disclosed. The apparatus includes a heating device which contains an assembly of light energy sources for emitting light energy onto a wafer. In particular, the light energy sources are positioned such that many different radial heating zones are created on a wafer being heated. For instance, in one embodiment, the light energy sources form a spiral configuration. In an alternative embodiment, the light energy sources appear to be randomly dispersed with respect to each other so that no discernable pattern is present. In a third alternative embodiment of the present invention, the light energy sources form concentric rings. Tuning light sources are then placed in between the concentric rings of light.

Heating device for semiconductor wafers

DOEpatents

Vosen, S.R.

1999-07-27

An apparatus for heat treating semiconductor wafers is disclosed. The apparatus includes a heating device which contains an assembly of light energy sources for emitting light energy onto a wafer. In particular, the light energy sources are positioned such that many different radial heating zones are created on a wafer being heated. For instance, in one embodiment, the light energy sources form a spiral configuration. In an alternative embodiment, the light energy sources appear to be randomly dispersed with respect to each other so that no discernible pattern is present. In a third alternative embodiment of the present invention, the light energy sources form concentric rings. Tuning light sources are then placed in between the concentric rings of light. 4 figs.

Definition phase study of the grand tour missions

NASA Technical Reports Server (NTRS)

Simpson, J. A.; Meyer, P.

1972-01-01

The research to define an energetic particle experiment for the OPTGT-MJS missions is reported. The studies reported include: (1) the use of silicon dectectors for low energy, low flux level measurements in the presence of RTG radiation and trapped electrons, (2) high energy proton damage of lithium-drifted and surface barrier silicon detectors, (3) the gas Cerenkov counter, (4) systems for detection of trapped high-energy protons in the presence of trapped electrons, and (5) reliability and redundancy.

Dysphagia Causes Symptom Fluctuations after Oral L-DOPA Treatment in a Patient with Parkinson Disease.

PubMed

Sato, Hiromasa; Yamamoto, Toshiyuki; Sato, Masako; Furusawa, Yoshihiko; Murata, Miho

2018-01-01

The causes of "delayed-on" and "no-on" phenomena in Parkinson disease (PD) are thought to have some impact on the progress of L-DOPA from the time of ingestion until it reaches the brain and is converted to dopamine. Dysphagia can cause fluctuating symptom expression in L-DOPA therapy for PD. A 69-year-old man with PD presented with "delayed-on" and "no-on" phenomena. The patient developed a gait disorder at age 60 years, and he began coughing on his food during breakfast at age 64 years. Even though he was independent in daily life, he could not eat because of dysphagia in an "off" state. Videofluoroscopic examination of swallowing in an "off" state revealed bradykinesia of the tongue and the retention of tablets in the epiglottic vallecula. We trained him to keep his tongue in strong contact with the upper incisors before swallowing. After rehabilitation of dysphagia, the frequency of "delayed-on" and "no-on" phenomena decreased, and his peak L-DOPA plasma concentration was elevated. Additionally, transdermal rotigotine (RTG) was initiated at a maintenance dose of 9.0 mg. The patient reported improvement in swallowing, and the frequency of "no-on" phenomena decreased. In PD patients, the "no-on" phenomenon can be caused by posterior contractile dysfunction of the tongue, and it can be improved with training of the tongue and transdermal RTG administration.

Step length after discrete perturbation predicts accidental falls and fall-related injury in elderly people with a range of peripheral neuropathy.

PubMed

Allet, Lara; Kim, Hogene; Ashton-Miller, James; De Mott, Trina; Richardson, James K

2014-01-01

Distal symmetric polyneuropathy increases fall risk due to inability to cope with perturbations. We aimed to 1) identify the frontal plane lower limb sensorimotor functions which are necessary for robustness to a discrete, underfoot perturbation during gait; and 2) determine whether changes in the post-perturbed step parameters could distinguish between fallers and non fallers. Forty-two subjects (16 healthy old and 26 with diabetic PN) participated. Frontal plane lower limb sensorimotor functions were determined using established laboratory-based techniques. The subjects' most extreme alterations in step width or step length in response to a perturbation were measured. In addition, falls and fall-related injuries were prospectively recorded. Ankle proprioceptive threshold (APrT; p=.025) and hip abduction rate of torque generation (RTG; p=.041) independently predicted extreme step length after medial perturbation, with precise APrT and greater hip RTG allowing maintenance of step length. Injured subjects demonstrated greater extreme step length changes after medial perturbation than non-injured subjects (percent change = 18.5 ± 9.2 vs. 11.3 ± 4.57; p = .01). The ability to rapidly generate frontal plane hip strength and/or precisely perceive motion at the ankle is needed to maintain a normal step length after perturbation, a parameter which distinguishes between subjects sustaining a fall-related injury and those who did not. © 2014.

Fish cell lines as a tool for the ecotoxicity assessment and ranking of engineered nanomaterials.

PubMed

Bermejo-Nogales, A; Fernández-Cruz, M L; Navas, J M

2017-11-01

Risk assessment of engineered nanomaterials (ENMs) is being hindered by the sheer production volume of these materials. In this regard, the grouping and ranking of ENMs appears as a promising strategy. Here we sought to evaluate the usefulness of in vitro systems based on fish cell lines for ranking a set of ENMs on the basis of their cytotoxicity. We used the topminnow (Poeciliopsis lucida) liver cell line (PLHC-1) and the rainbow trout (Oncorhynchus mykiss) fibroblast-like gonadal cell line (RTG-2). ENMs were obtained from the EU Joint Research Centre repository. The size frequency distribution of ENM suspensions in cell culture media was characterized. Cytotoxicity was evaluated after 24 h of exposure. PLHC-1 cells exhibited higher sensitivity to the ENMs than RTG-2 cells. ZnO-NM was found to exert toxicity mainly by altering lysosome function and metabolic activity, while multi-walled carbon nanotubes (MWCNTs) caused plasma membrane disruption at high concentrations. The hazard ranking for toxicity (ZnO-NM > MWCNT ≥ CeO 2 -NM = SiO 2 -NM) was inversely related to the ranking in size detected in culture medium. Our findings reveal the suitability of fish cell lines for establishing hazard rankings of ENMs in the framework of integrated approaches to testing and assessment. Copyright © 2017 Elsevier Inc. All rights reserved.

Step length after discrete perturbation predicts accidental falls and fall-related injury in elderly people with a range of peripheral neuropathy

PubMed Central

Allet, L; Kim, H; Ashton-Miller, JA; De Mott, T; Richardson, JK

2013-01-01

Aims Distal symmetric polyneuropathy increases fall risk due to inability to cope with perturbations. We aimed to 1) identify the frontal plane lower limb sensorimotor functions which are necessary for robustness to a discrete, underfoot perturbation during gait; and 2) determine whether changes in the post-perturbed step parameters could distinguish between fallers and non fallers. Methods Forty-two subjects (16 healthy old and 26 with diabetic PN) participated. Frontal plane lower limb sensorimotor functions were determined using established laboratory-based techniques. The subjects' most extreme alterations in step width or step length in response to a perturbation were measured. In addition, falls and fall-related injuries were prospectively recorded. Results Ankle proprioceptive threshold (APrT; p=.025) and hip abduction rate of torque generation (RTG; p=.041) independently predicted extreme step length after medial perturbation, with precise APrT and greater hip RTG allowing maintenance of step length. Fallers demonstrated greater extreme step length changes after medial perturbation than non fallers (percent change = 16.41±8.42 vs 11.0±4.95; p=.06) Conclusions The ability to rapidly generate frontal plane hip strength and/or precisely perceive motion at the ankle is needed to maintain a normal step length after perturbation, a parameter, which distinguishes between fallers and non fallers. PMID:24183899

Method and apparatus for fuel gas moisturization and heating

DOEpatents

Ranasinghe, Jatila; Smith, Raub Warfield

2002-01-01

Fuel gas is saturated with water heated with a heat recovery steam generator heat source. The heat source is preferably a water heating section downstream of the lower pressure evaporator to provide better temperature matching between the hot and cold heat exchange streams in that portion of the heat recovery steam generator. The increased gas mass flow due to the addition of moisture results in increased power output from the gas and steam turbines. Fuel gas saturation is followed by superheating the fuel, preferably with bottom cycle heat sources, resulting in a larger thermal efficiency gain compared to current fuel heating methods. There is a gain in power output compared to no fuel heating, even when heating the fuel to above the LP steam temperature.

Changes in concentration, composition and source contribution of atmospheric organic aerosols by shifting coal to natural gas in Urumqi

NASA Astrophysics Data System (ADS)

Ren, Yanqin; Wang, Gehui; Wu, Can; Wang, Jiayuan; Li, Jianjun; Zhang, Lu; Han, Yanni; Liu, Lang; Cao, Cong; Cao, Junji; He, Qing; Liu, Xinchun

2017-01-01

Size-segregated aerosols were collected in Urumqi, a megacity in northwest China, during two heating seasons, i.e., before (heating season І: January-March 2012) and after (heating season II: January-March 2014) the project "shifting coal to natural gas", and determined for n-alkanes, PAHs and oxygenated PAHs to investigate the impact of replacement of coal by natural gas on organic aerosols in the urban atmosphere. Our results showed that compared to those in heating season I concentrations of n-alkanes, PAHs and OPAHs decreased by 74%, 74% and 82% in heating season II, respectively. Source apportionment analysis suggested that coal combustion, traffic emission and biomass burning are the major sources of the determined organics during the heating seasons in Urumqi. Traffic emission is the main source for n-alkanes in the city. Coal combustion is the dominant source of PAHs and OPAHs in heating season І, but traffic emission becomes their major source in heating season ІI. Relative contributions of coal combustion to n-alkanes, PAHs and OPAHs in Urumqi decreased from 21 to 75% in heating season I to 4.0-21% in heating season II due to the replacement of coal with natural gas for house heating. Health risk assessment further indicated that compared with that in heating season I the number of lung cancer related to PAHs exposure in Urumqi decreased by 73% during heating season II due to the project implementation. Our results suggest that replacing coal by clean energy sources for house heating will significantly mitigate air pollution and improve human health in China.

10 CFR 431.92 - Definitions concerning commercial air conditioners and heat pumps.

Code of Federal Regulations, 2010 CFR

2010-01-01

... wall, and that is industrial equipment. It includes a prime source of refrigeration, separable outdoor... refrigeration as its prime heat source, that has a supplementary heat source available, with the choice of hot... water, or gas, but may not include reverse cycle refrigeration as a heating means. Single package...

10 CFR 431.92 - Definitions concerning commercial air conditioners and heat pumps.

Code of Federal Regulations, 2011 CFR

2011-01-01

... wall, and that is industrial equipment. It includes a prime source of refrigeration, separable outdoor... refrigeration as its prime heat source, that has a supplementary heat source available, with the choice of hot... water, or gas, but may not include reverse cycle refrigeration as a heating means. Single package...

10 CFR 431.92 - Definitions concerning commercial air conditioners and heat pumps.

Code of Federal Regulations, 2012 CFR

2012-01-01

... mounting through the wall, and that is industrial equipment. It includes a prime source of refrigeration... utilizes reverse cycle refrigeration as its prime heat source, that has a supplementary heat source..., hot water, or gas, but may not include reverse cycle refrigeration as a heating means. Single package...

Heat source reconstruction from noisy temperature fields using a gradient anisotropic diffusion filter

NASA Astrophysics Data System (ADS)

Beitone, C.; Balandraud, X.; Delpueyo, D.; Grédiac, M.

2017-01-01

This paper presents a post-processing technique for noisy temperature maps based on a gradient anisotropic diffusion (GAD) filter in the context of heat source reconstruction. The aim is to reconstruct heat source maps from temperature maps measured using infrared (IR) thermography. Synthetic temperature fields corrupted by added noise are first considered. The GAD filter, which relies on a diffusion process, is optimized to retrieve as well as possible a heat source concentration in a two-dimensional plate. The influence of the dimensions and the intensity of the heat source concentration are discussed. The results obtained are also compared with two other types of filters: averaging filter and Gaussian derivative filter. The second part of this study presents an application for experimental temperature maps measured with an IR camera. The results demonstrate the relevancy of the GAD filter in extracting heat sources from noisy temperature fields.

Solid state lighting devices and methods with rotary cooling structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koplow, Jeffrey P.

Solid state lighting devices and methods for heat dissipation with rotary cooling structures are described. An example solid state lighting device includes a solid state light source, a rotating heat transfer structure in thermal contact with the solid state light source, and a mounting assembly having a stationary portion. The mounting assembly may be rotatably coupled to the heat transfer structure such that at least a portion of the mounting assembly remains stationary while the heat transfer structure is rotating. Examples of methods for dissipating heat from electrical devices, such as solid state lighting sources are also described. Heat dissipationmore » methods may include providing electrical power to a solid state light source mounted to and in thermal contact with a heat transfer structure, and rotating the heat transfer structure through a surrounding medium.« less

Method for welding an article and terminating the weldment within the perimeter of the article

NASA Technical Reports Server (NTRS)

Snyder, John H. (Inventor); Smashey, Russell W. (Inventor); Boerger, Eric J. (Inventor); Borne, Bruce L. (Inventor)

2000-01-01

An article is welded, as in weld repair of a defect, by positioning a weld lift-off block at a location on the surface of the article adjacent to the intended location of the end of the weldment on the surface of the article. The weld lift-off block has a wedge shape including a base contacting the surface of the article, and an upper face angled upwardly from the base from a base leading edge. A weld pool is formed on the surface of the article by directly heating the surface of the article using a heat source. The heat source is moved relative to the surface of the article and onto the upper surface of the weld lift-off block by crossing the leading edge of the wedge, without discontinuing the direct heating of the article by the heat source. The heating of the article with the heat source is discontinued only after the heat source is directly heating the upper face of the weld lift-off block, and not the article.

Contact Force Compensated Thermal Stimulators for Holistic Haptic Interfaces.

PubMed

Sim, Jai Kyoung; Cho, Young-Ho

2016-05-01

We present a contact force compensated thermal stimulator that can provide a consistent tempera- ture sensation on the human skin independent of the contact force between the thermal stimulator and the skin. Previous passive thermal stimulators were not capable of providing a consistent tem- perature on the human skin even when using identical heat source voltage due to an inconsistency of the heat conduction, which changes due to the force-dependent thermal contact resistance. We propose a force-based feedback method that monitors the contact force and controls the heat source voltage according to this contact force, thus providing consistent temperature on the skin. We composed a heat circuit model equivalent to the skin heat-transfer rate as it is changed by the contact forces; we obtained the optimal voltage condition for the constant skin heat-transfer rate independent of the contact force using a numerical estimation simulation tool. Then, in the experiment, we heated real human skin at the obtained heat source voltage condition, and investigated the skin heat transfer-rate by measuring the skin temperature at various times at different levels of contact force. In the numerical estimation results, the skin heat-transfer rate for the contact forces showed a linear profile in the contact force range of 1-3 N; from this profile we obtained the voltage equation for heat source control. In the experimental study, we adjusted the heat source voltage according to the contact force based on the obtained equation. As a result, without the heat source voltage control for the contact forces, the coefficients of variation (CV) of the skin heat-transfer rate in the contact force range of 1-3 N was found to be 11.9%. On the other hand, with the heat source voltage control for the contact forces, the CV of the skin heat-transfer rate in the contact force range of 1-3 N was found to be barely 2.0%, which indicate an 83.2% improvement in consistency compared to the skin heat-transfer rate without the heat source voltage control. The present technique provides a consistent temperature sensation on the human skin independent of the body movement environment; therefore, it has high potential for use in holistic haptic interfaces that have thermal displays.

Characterizing open and non-uniform vertical heat sources: towards the identification of real vertical cracks in vibrothermography experiments

NASA Astrophysics Data System (ADS)

Castelo, A.; Mendioroz, A.; Celorrio, R.; Salazar, A.; López de Uralde, P.; Gorosmendi, I.; Gorostegui-Colinas, E.

2017-05-01

Lock-in vibrothermography is used to characterize vertical kissing and open cracks in metals. In this technique the crack heats up during ultrasound excitation due mainly to friction between the defect's faces. We have solved the inverse problem, consisting in determining the heat source distribution produced at cracks under amplitude modulated ultrasound excitation, which is an ill-posed inverse problem. As a consequence the minimization of the residual is unstable. We have stabilized the algorithm introducing a penalty term based on Total Variation functional. In the inversion, we combine amplitude and phase surface temperature data obtained at several modulation frequencies. Inversions of synthetic data with added noise indicate that compact heat sources are characterized accurately and that the particular upper contours can be retrieved for shallow heat sources. The overall shape of open and homogeneous semicircular strip-shaped heat sources representing open half-penny cracks can also be retrieved but the reconstruction of the deeper end of the heat source loses contrast. Angle-, radius- and depth-dependent inhomogeneous heat flux distributions within these semicircular strips can also be qualitatively characterized. Reconstructions of experimental data taken on samples containing calibrated heat sources confirm the predictions from reconstructions of synthetic data. We also present inversions of experimental data obtained from a real welded Inconel 718 specimen. The results are in good qualitative agreement with the results of liquids penetrants testing.

Awareness of Emerging Wireless Technologies: Ad-hoc and Personal Area Networks Standards and Emerging Technologies (Sensibilisation a l’emergence des technologies sans fil: technologies emergeantes et normes de reseaux personnels et ad-hoc)

DTIC Science & Technology

2007-04-01

for the collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data...Control Organization NRL Navy Research Laboratory nrtPS Non-real- time Polling Services OFDM Orthogonal frequency division multiplex OFDMA...Routeur IDentifier RTG RTO Task Group RTO Research & Technology Organization rtPS Real- time Polling Services SC Single-carrier modulation

Toward Intelligent Autonomous Agents for Cyber Defense: Report of the 2017 Workshop by the North Atlantic Treaty Organization (NATO) Research Group IST-152 RTG

DTIC Science & Technology

2018-04-18

Significant research is currently conducted on dynamic learning and threat detection. However, this work is held back by gaps in validation methods ...and network path rotation (e.g., Stream Splitting MTD). Agents can also employ various cyber-deception methods , including direct observation hiding...ARL-SR-0395 ● APR 2018 US Army Research Laboratory Toward Intelligent Autonomous Agents for Cyber Defense: Report of the 2017

Toward Intelligent Autonomous Agents for Cyber Defense: Report of the 2017 Workshop by the North Atlantic Treaty Organization (NATO) Research Group IST-152-RTG

DTIC Science & Technology

2018-04-01

Significant research is currently conducted on dynamic learning and threat detection. However, this work is held back by gaps in validation methods ...and network path rotation (e.g., Stream Splitting MTD). Agents can also employ various cyber-deception methods , including direct observation hiding...ARL-SR-0395 ● APR 2018 US Army Research Laboratory Toward Intelligent Autonomous Agents for Cyber Defense: Report of the 2017

Advanced radioisotope heat source for Stirling Engines

NASA Astrophysics Data System (ADS)

Dobry, T. J.; Walberg, G.

2001-02-01

The heat exchanger on a Stirling Engine requires a thermal energy transfer from a heat source to the engine through a very limited area on the heater head circumference. Designing an effective means to assure maximum transfer efficiency is challenging. A single General Purpose Heat Source (GPHS), which has been qualified for space operations, would satisfy thermal requirements for a single Stirling Engine that would produce 55 electrical watts. However, it is not efficient to transfer its thermal energy to the engine heat exchanger from its rectangular geometry. This paper describes a conceptual design of a heat source to improve energy transfer for Stirling Engines that may be deployed to power instrumentation on space missions. .

The Influence of Ocean on Typhoon Nuri (2008)

NASA Astrophysics Data System (ADS)

Sun, J.; Oey, L. Y.; Xu, F.; Lin, Y.; Huang, S. M.; Chang, R.

2014-12-01

The influence of ocean on typhoon Nuri (2008) is investigated in this study using the WRF numerical model. Typhoon Nuri formed over the warm pool of the western North Pacific. The storm traversed west-northwestward and became a Category 3 typhoon over the Kuroshio east of the Luzon Strait and weakened as it moved across South China Sea. Three types of SST: NCEP RTG_SST (Real-time，global，sea surface temperature) GHRsst (Group for High Resolution Sea Surface Temperature) and SST from the ATOP North Pacific ocean model [Oey et al 2014, JPO] are used in WRF to test the effect of ocean on the intensity of typhoon Nuri. The typhoon intensity and track are also compared with simulations using different microphysics schemes but with fixed SST. The results show that thermodynamic control through ocean response is the dominant factor which determines Nuri's intensity. The simulated intensity agrees well with the observed intensity when ATOP SST is used, while using NCEP SST and GHRsst yield errors both in intensity and timing of maximum intensity. Over the Kuroshio, the thicker depth of 26 ℃ from ATOP provides stronger heating for the correct timing of intensification of Nuri. In South China Sea, the storm weakened because of cooled SST through ocean mixing by inertial resonance. A new way of explaining typhoon intensification though PV is proposed.

A new regime of nanoscale thermal transport: Collective diffusion increases dissipation efficiency

DOE PAGES

Hoogeboom-Pot, Kathleen M.; Hernandez-Charpak, Jorge N.; Gu, Xiaokun; ...

2015-03-23

Understanding thermal transport from nanoscale heat sources is important for a fundamental description of energy flow in materials, as well as for many technological applications including thermal management in nanoelectronics and optoelectronics, thermoelectric devices, nanoenhanced photovoltaics, and nanoparticle-mediated thermal therapies. Thermal transport at the nanoscale is fundamentally different from that at the macroscale and is determined by the distribution of carrier mean free paths and energy dispersion in a material, the length scales of the heat sources, and the distance over which heat is transported. Past work has shown that Fourier’s law for heat conduction dramatically overpredicts the rate ofmore » heat dissipation from heat sources with dimensions smaller than the mean free path of the dominant heat-carrying phonons. In this work, we uncover a new regime of nanoscale thermal transport that dominates when the separation between nanoscale heat sources is small compared with the dominant phonon mean free paths. Surprisingly, the interaction of phonons originating from neighboring heat sources enables more efficient diffusive-like heat dissipation, even from nanoscale heat sources much smaller than the dominant phonon mean free paths. This finding suggests that thermal management in nanoscale systems including integrated circuits might not be as challenging as previously projected. In conclusion, we demonstrate a unique capability to extract differential conductivity as a function of phonon mean free path in materials, allowing the first (to our knowledge) experimental validation of predictions from the recently developed first-principles calculations.« less

A new regime of nanoscale thermal transport: Collective diffusion increases dissipation efficiency

NASA Astrophysics Data System (ADS)

Hoogeboom-Pot, Kathleen M.; Hernandez-Charpak, Jorge N.; Gu, Xiaokun; Frazer, Travis D.; Anderson, Erik H.; Chao, Weilun; Falcone, Roger W.; Yang, Ronggui; Murnane, Margaret M.; Kapteyn, Henry C.; Nardi, Damiano

2015-04-01

Understanding thermal transport from nanoscale heat sources is important for a fundamental description of energy flow in materials, as well as for many technological applications including thermal management in nanoelectronics and optoelectronics, thermoelectric devices, nanoenhanced photovoltaics, and nanoparticle-mediated thermal therapies. Thermal transport at the nanoscale is fundamentally different from that at the macroscale and is determined by the distribution of carrier mean free paths and energy dispersion in a material, the length scales of the heat sources, and the distance over which heat is transported. Past work has shown that Fourier's law for heat conduction dramatically overpredicts the rate of heat dissipation from heat sources with dimensions smaller than the mean free path of the dominant heat-carrying phonons. In this work, we uncover a new regime of nanoscale thermal transport that dominates when the separation between nanoscale heat sources is small compared with the dominant phonon mean free paths. Surprisingly, the interaction of phonons originating from neighboring heat sources enables more efficient diffusive-like heat dissipation, even from nanoscale heat sources much smaller than the dominant phonon mean free paths. This finding suggests that thermal management in nanoscale systems including integrated circuits might not be as challenging as previously projected. Finally, we demonstrate a unique capability to extract differential conductivity as a function of phonon mean free path in materials, allowing the first (to our knowledge) experimental validation of predictions from the recently developed first-principles calculations.

Pyrolysis reactor and fluidized bed combustion chamber

DOEpatents

Green, Norman W.

1981-01-06

A solid carbonaceous material is pyrolyzed in a descending flow pyrolysis reactor in the presence of a particulate source of heat to yield a particulate carbon containing solid residue. The particulate source of heat is obtained by educting with a gaseous source of oxygen the particulate carbon containing solid residue from a fluidized bed into a first combustion zone coupled to a second combustion zone. A source of oxygen is introduced into the second combustion zone to oxidize carbon monoxide formed in the first combustion zone to heat the solid residue to the temperature of the particulate source of heat.

Transient performance and temperature field of a natural convection air dehumidifier loop

NASA Astrophysics Data System (ADS)

Fazilati, Mohammad Ali; Sedaghat, Ahmad; Alemrajabi, Ali-Akbar

2017-07-01

In this paper, transient performance of the previously introduced natural convection heat and mass transfer loop is investigated for an air dehumidifier system. The performance of the loop is studied in different conditions of heat source/heat sink temperature and different startup desiccant concentrations. Unlike conventional loops, it is observed that natural convection of the fluid originates from the heat sink towards the heat source. The proper operation of the cycle is highly dependent on the heat sink/heat source temperatures. To reduce the time constant of the system, a proper desiccant concentration should be adopted for charge of the loop.

Mini-Brayton heat source assembly development

NASA Technical Reports Server (NTRS)

Wein, D.; Zimmerman, W. F.

1978-01-01

The work accomplished on the Mini-Brayton Heat Source Assembly program is summarized. Required technologies to design, fabricate and assemble components for a high temperature Heat Source Assembly (HSA) which would generate and transfer the thermal energy for a spaceborne Brayton Isotope Power System (BIPS) were developed.

Simulation of the thermal performance of a hybrid solar-assisted ground-source heat pump system in a school building

NASA Astrophysics Data System (ADS)

Androulakis, N. D.; Armen, K. G.; Bozis, D. A.; Papakostas, K. T.

2018-04-01

A hybrid solar-assisted ground-source heat pump (SAGSHP) system was designed, in the frame of an energy upgrade study, to serve as a heating system in a school building in Greece. The main scope of this study was to examine techniques to reduce the capacity of the heating equipment and to keep the primary energy consumption low. Simulations of the thermal performance of both the building and of five different heating system configurations were performed by using the TRNSYS software. The results are presented in this work and show that the hybrid SAGSHP system displays the lower primary energy consumption among the systems examined. A conventional ground-source heat pump system has the same primary energy consumption, while the heat pump's capacity is double and the ground heat exchanger 2.5 times longer. This work also highlights the contribution of simulation tools to the design of complex heating systems with renewable energy sources.

Application of sorption heat pumps for increasing of new power sources efficiency

NASA Astrophysics Data System (ADS)

Vasiliev, L.; Filatova, O.; Tsitovich, A.

2010-07-01

In the 21st century the way to increase the efficiency of new sources of energy is directly related with extended exploration of renewable energy. This modern tendency ensures the fuel economy needs to be realized with nature protection. The increasing of new power sources efficiency (cogeneration, trigeneration systems, fuel cells, photovoltaic systems) can be performed by application of solid sorption heat pumps, regrigerators, heat and cold accumulators, heat transformers, natural gas and hydrogen storage systems and efficient heat exchangers.

Hydride heat pump

DOEpatents

Cottingham, James G.

1977-01-01

Method and apparatus for the use of hydrides to exhaust heat from one temperature source and deliver the thermal energy extracted for use at a higher temperature, thereby acting as a heat pump. For this purpose there are employed a pair of hydridable metal compounds having different characteristics working together in a closed pressure system employing a high temperature source to upgrade the heat supplied from a low temperature source.

Final safety analysis report for the Galileo Mission: Volume 1, Reference design document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The Galileo mission uses nuclear power sources called Radioisotope Thermoelectric Generators (RTGs) to provide the spacecraft's primary electrical power. Because these generators contain nuclear material, a Safety Analysis Report (SAR) is required. A preliminary SAR and an updated SAR were previously issued that provided an evolving status report on the safety analysis. As a result of the Challenger accident, the launch dates for both Galileo and Ulysses missions were later rescheduled for November 1989 and October 1990, respectively. The decision was made by agreement between the DOE and the NASA to have a revised safety evaluation and report (FSAR) preparedmore » on the basis of these revised vehicle accidents and environments. The results of this latest revised safety evaluation are presented in this document (Galileo FSAR). Volume I, this document, provides the background design information required to understand the analyses presented in Volumes II and III. It contains descriptions of the RTGs, the Galileo spacecraft, the Space Shuttle, the Inertial Upper Stage (IUS), the trajectory and flight characteristics including flight contingency modes, and the launch site. There are two appendices in Volume I which provide detailed material properties for the RTG.« less

SAGA complex and Gcn5 are necessary for respiration in budding yeast.

PubMed

Canzonetta, Claudia; Leo, Manuela; Guarino, Salvatore Rocco; Montanari, Arianna; Francisci, Silvia; Filetici, Patrizia

2016-12-01

In budding yeast, growth through fermentation and/or respiration is dependent on the type of carbon source present in the medium. SAGA complex is the main acetylation complex and is required, together with Rtg factors, for nucleus-mitochondria communication and transcriptional activation of specific nuclear genes. Even though acetylation is necessary for mitochondria activity and respiratory pathways the direct role of histone acetyltransferases and SAGA complex has never been investigated directly. In this study we demonstrate, for the first time, that Gcn5 and SAGA are needed for respiratory metabolism and oxygen consumption. According to a central role for acetylation in respiration we find that the Gcn5 inhibitor CPTH2 had higher efficacy on cells grown in glycerol containing media. We also demonstrated that the opposing activities of Gcn5 and Hda1 modify selectively H3-AcK18 and are essential for respiration. Taken together our results suggest a novel paradigm coupling acetyltransferase activity to respiratory metabolism. Correspondingly we propose the selective utilization of KAT inhibitor CPTH2, combined to the modulation of the respiratory metabolism of the cell, as a promising novel tool of intervention in cancer cells. Copyright © 2016 Elsevier B.V. All rights reserved.

Reducing residential solid fuel combustion through electrified space heating leads to substantial air quality, health and climate benefits in China's Beijing-Tianjin-Hebei region

NASA Astrophysics Data System (ADS)

Yang, J.; Mauzerall, D. L.

2017-12-01

During periods of high pollution in winter, household space heating can contribute more than half of PM2.5 concentrations in China's Beijing-Tianjin-Hebei (BTH) region. The majority of rural households and some urban households in the region still heat with small stoves and solid fuels such as raw coal, coal briquettes and biomass. Thus, reducing emissions from residential space heating has become a top priority of the Chinese government's air pollution mitigation plan. Electrified space heating is a promising alternative to solid fuel. However, there is little analysis of the air quality and climate implications of choosing various electrified heating devices and utilizing different electricity sources. Here we conduct an integrated assessment of the air quality, human health and climate implications of various electrified heating scenarios in the BTH region using the Weather Research and Forecasting model with Chemistry. We use the Multi-resolution Emission Inventory for China for the year 2012 as our base case and design two electrification scenarios in which either direct resistance heaters or air source heat pumps are installed to replace all household heating stoves. We initially assume all electrified heating devices use electricity from supercritical coal-fired power plants. We find that installing air source heat pumps reduces CO2 emissions and premature deaths due to PM2.5 pollution more than resistance heaters, relative to the base case. The increased health and climate benefits of heat pumps occur because they have a higher heat conversion efficiency and thus require less electricity for space heating than resistance heaters. We also find that with the same heat pump installation, a hybrid electricity source (40% of the electricity generated from renewable sources and the rest from coal) further reduces both CO2 emissions and premature deaths than using electricity only from coal. Our study demonstrates the air pollution and CO2 mitigation potential and public health benefits of using electrified space heating. In particular, we find air source heat pumps could bring more climate and health benefits than direct resistance heaters. Our results also support policies to integrate renewable energy sources with the reduction of solid fuel combustion for residential space heating.

High-temperature self-circulating thermoacoustic heat exchanger

NASA Astrophysics Data System (ADS)

Backhaus, S.; Swift, G. W.; Reid, R. S.

2005-07-01

Thermoacoustic and Stirling engines and refrigerators use heat exchangers to transfer heat between the oscillating flow of their thermodynamic working fluids and external heat sources and sinks. An acoustically driven heat-exchange loop uses an engine's own pressure oscillations to steadily circulate its own thermodynamic working fluid through a physically remote high-temperature heat source without using moving parts, allowing for a significant reduction in the cost and complexity of thermoacoustic and Stirling heat exchangers. The simplicity and flexibility of such heat-exchanger loops will allow thermoacoustic and Stirling machines to access diverse heat sources and sinks. Measurements of the temperatures at the interface between such a heat-exchange loop and the hot end of a thermoacoustic-Stirling engine are presented. When the steady flow is too small to flush out the mixing chamber in one acoustic cycle, the heat transfer to the regenerator is excellent, with important implications for practical use.

The Prestige oil spill: a laboratory study about the toxicity of the water-soluble fraction of the fuel oil.

PubMed

Navas, José M; Babín, Mar; Casado, Susana; Fernández, Carlos; Tarazona, José V

2006-07-01

The Prestige oil spill caused severe effects on the coastal fauna and flora due to direct contact of organisms with the fuel oil. However, the water soluble fraction (WSF) of the fuel oil can also provoke deleterious effects in the long term and even in regions not directly affected by the spill. Our objective was to determine the toxicity of the WSF using a battery of laboratory toxicity tests. To obtain a WSF in the laboratory, a sample of the spilled fuel was mixed with adequate medium, sonicated, agitated and filtered. No cytotoxic effects were detected in RTG-2 cells exposed to the WSF. In an algae growth inhibition test (OECD test guideline 201) the WSF did not affect the growth of Chlorella vulgaris. Furthermore, acute and reproductive toxicity tests (OECD test guideline 202) carried out using Daphnia magna did not indicate any deleterious effect of the WSF. In a bioassay designed in our laboratory, D. magna were fed with algae previously exposed to the fuel, but no toxic effects were detected. However, the WSF was able to induce a dose-dependent increase of ethoxyresorufin-O-deethylase activity in RTG-2 cells, indicating the presence of chemicals that could cause sub-lethal effects to organisms. After chemical analyses it was established that the final total quantity of polyaromatic hydrocarbons dissolved in medium was approximately 70 ng/ml. These low concentrations explain the observed lack of toxicity.

Heating systems for heating subsurface formations

DOEpatents

Nguyen, Scott Vinh [Houston, TX; Vinegar, Harold J [Bellaire, TX

2011-04-26

Methods and systems for heating a subsurface formation are described herein. A heating system for a subsurface formation includes a sealed conduit positioned in an opening in the formation and a heat source. The sealed conduit includes a heat transfer fluid. The heat source provides heat to a portion of the sealed conduit to change phase of the heat transfer fluid from a liquid to a vapor. The vapor in the sealed conduit rises in the sealed conduit, condenses to transfer heat to the formation and returns to the conduit portion as a liquid.

Inverse problem and variation method to optimize cascade heat exchange network in central heating system

NASA Astrophysics Data System (ADS)

Zhang, Yin; Wei, Zhiyuan; Zhang, Yinping; Wang, Xin

2017-12-01

Urban heating in northern China accounts for 40% of total building energy usage. In central heating systems, heat is often transferred from heat source to users by the heat network where several heat exchangers are installed at heat source, substations and terminals respectively. For given overall heating capacity and heat source temperature, increasing the terminal fluid temperature is an effective way to improve the thermal performance of such cascade heat exchange network for energy saving. In this paper, the mathematical optimization model of the cascade heat exchange network with three-stage heat exchangers in series is established. Aim at maximizing the cold fluid temperature for given hot fluid temperature and overall heating capacity, the optimal heat exchange area distribution and the medium fluids' flow rates are determined through inverse problem and variation method. The preliminary results show that the heat exchange areas should be distributed equally for each heat exchanger. It also indicates that in order to improve the thermal performance of the whole system, more heat exchange areas should be allocated to the heat exchanger where flow rate difference between two fluids is relatively small. This work is important for guiding the optimization design of practical cascade heating systems.

Impact of various operating modes on performance and emission parameters of small heat source

NASA Astrophysics Data System (ADS)

Vician, Peter; Holubčík, Michal; Palacka, Matej; Jandačka, Jozef

2016-06-01

Thesis deals with the measurement of performance and emission parameters of small heat source for combustion of biomass in each of its operating modes. As the heat source was used pellet boiler with an output of 18 kW. The work includes design of experimental device for measuring the impact of changes in air supply and method for controlling the power and emission parameters of heat sources for combustion of woody biomass. The work describes the main factors that affect the combustion process and analyze the measurements of emissions at the heat source. The results of experiment demonstrate the values of performance and emissions parameters for the different operating modes of the boiler, which serve as a decisive factor in choosing the appropriate mode.

Defense Small Business Innovation Research Program (SBIR) Abstracts of Phase I Awards 1984.

DTIC Science & Technology

1985-04-16

PROTECTION OF SATELLITES FROM DIRECTED ENERGY WEAPONS, IS THE UTILIZATION OF HEAT PIPES WITHIN A SHIELD STRUCTURE. HEAT PIPES COULD BE DESIGNED TO...780 EDEN ROAD LANCASTER, PA 17601 ROBERT M. SHAUBACK TITLE: ANALYSIS AND PERFORMNCE EVALUATION OF HEAT PIPES WITH MULTIPLE HEAT SOURCES TOPIC: 97... PIPES CAPABLE OF ACCEPTING HEAT FROM MULTIPLE HEAT SOURCES. THERE IS NO THOROUGH ANALYTICAL OR EXPERIMENTAL BASIS FOR THE DESIGN OF HEAT PIPES OF

Contraindications for superficial heat and therapeutic ultrasound: do sources agree?

PubMed

Batavia, Mitchell

2004-06-01

To determine the amount of agreement among general rehabilitation sources for both superficial heating and therapeutic ultrasound contraindications. English-language textbook and peer-reviewed journal sources, from January 1992 to July 2002. Searches of computerized databases (HealthSTAR, CINAHL, MEDLINE, Embase) as well as Library of Congress Online Catalogs, Books in Print, and AcqWeb's Directory of Publishers and Venders. Sources were excluded if they (1) were published before 1992, (2) failed to address general rehabilitation audiences, or (3) were identified as a researcher's related publication with similar information on the topic. Type and number of contraindications, type of audience, year of publication, number of references, rationales, and alternative treatment strategies. Eighteen superficial heat and 20 ultrasound sources identified anywhere from 5 to 22 and 9 to 36 contraindications/precautions, respectively. Agreement among sources was generally high but ranged from 11% to 95%, with lower agreement noted for pregnancy, metal implants, edema, skin integrity, and cognitive/communicative concerns. Seventy-two percent of superficial heat sources and 25% of ultrasound sources failed to reference at least 1 contraindication claim. Agreement among contraindication sources was generally good for both superficial heat and therapeutic ultrasound. Sources varied with regard to the number of contraindications, references, and rationales cited. Greater reliance on objective data and standardized classification systems may serve to develop more uniform guidelines for superficial heat and therapeutic ultrasound.

Low to high temperature energy conversion system

NASA Technical Reports Server (NTRS)

Miller, C. G. (Inventor)

1977-01-01

A method for converting heat energy from low temperature heat sources to higher temperature was developed. It consists of a decomposition chamber in which ammonia is decomposed into hydrogen and nitrogen by absorbing heat of decomposition from a low temperature energy source. A recombination reaction then takes place which increases the temperature of a fluid significantly. The system is of use for the efficient operation of compact or low capital investment turbine driven electrical generators, or in other applications, to enable chemical reactions that have a critical lower temperature to be used. The system also recovers heat energy from low temperature heat sources, such as solar collectors or geothermal sources, and converts it to high temperatures.

Post-evaluation of a ground source heat pump system for residential space heating in Shanghai China

NASA Astrophysics Data System (ADS)

Lei, Y.; Tan, H. W.; Wang, L. Z.

2017-11-01

Residents of Southern China are increasingly concerned about the space heating in winter. The chief aim of the present work is to find a cost-effective way for residential space heating in Shanghai, one of the biggest city in south China. Economic and energy efficiency of three residential space heating ways, including ground source heat pump (GSHP), air source heat pump (ASHP) and wall-hung gas boiler (WHGB), are assessed based on Long-term measured data. The results show that the heat consumption of the building is 120 kWh/m2/y during the heating season, and the seasonal energy efficiency ratio (SEER) of the GSHP, ASHP and WHGB systems are 3.27, 2.30, 0.88 respectively. Compared to ASHP and WHGB, energy savings of GSHP during the heating season are 6.2 kgce/(m2.y) and 2.2 kgce/(m2.y), and the payback period of GSHP are 13.3 and 7.6 years respectively. The sensitivity analysis of various factors that affect the payback period is carried out, and the results suggest that SEER is the most critical factor affecting the feasibility of ground source heat pump application, followed by building load factor and energy price factor. These findings of the research have led the author to the conclusion that ground source heat pump for residential space heating in Shanghai is a good alternative, which can achieve significant energy saving benefits, and a good system design and operation management are key factors that can shorten the payback period.

Analysis of classical Fourier, SPL and DPL heat transfer model in biological tissues in presence of metabolic and external heat source

NASA Astrophysics Data System (ADS)

Kumar, Dinesh; Singh, Surjan; Rai, K. N.

2016-06-01

In this paper, the temperature distribution in a finite biological tissue in presence of metabolic and external heat source when the surface subjected to different type of boundary conditions is studied. Classical Fourier, single-phase-lag (SPL) and dual-phase-lag (DPL) models were developed for bio-heat transfer in biological tissues. The analytical solution obtained for all the three models using Laplace transform technique and results are compared. The effect of the variability of different parameters such as relaxation time, metabolic heat source, spatial heat source, different type boundary conditions on temperature distribution in different type of the tissues like muscle, tumor, fat, dermis and subcutaneous based on three models are analyzed and discussed in detail. The result obtained in three models is compared with experimental observation of Stolwijk and Hardy (Pflug Arch 291:129-162, 1966). It has been observe that the DPL bio-heat transfer model provides better result in comparison of other two models. The value of metabolic and spatial heat source in boundary condition of first, second and third kind for different type of thermal therapies are evaluated.

Internal heat gain from different light sources in the building lighting systems

NASA Astrophysics Data System (ADS)

Suszanowicz, Dariusz

2017-10-01

EU directives and the Construction Law have for some time required investors to report the energy consumption of buildings, and this has indeed caused low energy consumption buildings to proliferate. Of particular interest, internal heat gains from installed lighting affect the final energy consumption for heating of both public and residential buildings. This article presents the results of analyses of the electricity consumption and the luminous flux and the heat flux emitted by different types of light sources used in buildings. Incandescent light, halogen, compact fluorescent bulbs, and LED bulbs from various manufacturers were individually placed in a closed and isolated chamber, and the parameters for their functioning under identical conditions were recorded. The heat flux emitted by 1 W nominal power of each light source was determined. Based on the study results, the empirical coefficients of heat emission and energy efficiency ratios for different types of lighting sources (dependent lamp power and the light output) were designated. In the heat balance of the building, the designated rates allow for precise determination of the internal heat gains coming from lighting systems using various light sources and also enable optimization of lighting systems of buildings that are used in different ways.

Performance Analysis of a Ground Source Heat Pump System Using Mine Water as Heat Sink and Source

DOE PAGES

Liu, Xiaobing; Malhotra, Mini; Walburger, Adam; ...

2016-06-01

This paper summarizes a case study of an innovative ground source heat pump (GSHP) system that uses flooded mines as a heat source and heat sink. This GSHP system provides space conditioning to a 56,000 sq ft 2(5,203 m 2) newly constructed research facility, in conjunction with supplementary existing steam heating and air-cooled chiller systems. Heat transfer performance and overall efficiency of the GSHP system were analysed using the available measured data from January through July 2014. The performance analysis identified some issues with using mine water for cooling and the integration of the GSHP system with the existing steammore » heating system. Recommendations were made to improve the control and operation of the GSHP system. These recommendations, in conjunction with the available measured data, were used to predict the annual energy use of the system. Finally, the energy and cost savings and CO 2 emission reduction potential of the GSHP system were estimated by comparing with a baseline scenario. This case study provides insights into the performance of and potential issues with the mine-water source heat pump system, which is relatively under-explored compared to other GSHP system designs and configurations.« less

Numerical analysis of the heat source characteristics of a two-electrode TIG arc

NASA Astrophysics Data System (ADS)

Ogino, Y.; Hirata, Y.; Nomura, K.

2011-06-01

Various kinds of multi-electrode welding processes are used to ensure high productivity in industrial fields such as shipbuilding, automotive manufacturing and pipe fabrication. However, it is difficult to obtain the optimum welding conditions for a specific product, because there are many operating parameters, and because welding phenomena are very complicated. In the present research, the heat source characteristics of a two-electrode TIG arc were numerically investigated using a 3D arc plasma model with a focus on the distance between the two electrodes. The arc plasma shape changed significantly, depending on the electrode spacing. The heat source characteristics, such as the heat input density and the arc pressure distribution, changed significantly when the electrode separation was varied. The maximum arc pressure of the two-electrode TIG arc was much lower than that of a single-electrode TIG. However, the total heat input of the two-electrode TIG arc was nearly constant and was independent of the electrode spacing. These heat source characteristics of the two-electrode TIG arc are useful for controlling the heat input distribution at a low arc pressure. Therefore, these results indicate the possibility of a heat source based on a two-electrode TIG arc that is capable of high heat input at low pressures.

Geothermal heat pumps for heating and cooling

NASA Astrophysics Data System (ADS)

Garg, Suresh C.

1994-03-01

Naval Facilities Engineering Service Center (NFESC) has been tasked by Naval Shore Facilities Energy Office to evaluate the NAS Patuxent River ground-source heat pump (GHP) installation. A large part of a building's energy consumption consists of heating and air conditioning for occupant comfort. The space heating requirements are normally met by fossil-fuel-fired equipment or electric resistance heating. Cooling is provided by either air conditioners or heat pumps, both using electricity as an energy source.

It's Hard Saying Goodbye to an Old Flame

ERIC Educational Resources Information Center

Roy, Ken

2004-01-01

As heat sources go, the old standby for elementary and middle school science laboratories has been the centuries old alcohol lamp. Unfortunately, this inexpensive heat producer has been a continuous source of accidents--many of which are relatively serious. Hot plates are emerging as the most popular source of heat for science experiments. The…

Simulation of the alpha particle heating and the helium ash source in an International Thermonuclear Experimental Reactor-like tokamak with an internal transport barrier

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ye, Lei, E-mail: lye@ipp.ac.cn; Guo, Wenfeng; Xiao, Xiaotao

2014-12-15

A guiding center orbit following code, which incorporates a set of non-singular coordinates for orbit integration, was developed and applied to investigate the alpha particle heating in an ITER-like tokamak with an internal transport barrier. It is found that a relatively large q (safety factor) value can significantly broaden the alpha heating profile in comparison with the local heating approximation; this broadening is due to the finite orbit width effects; when the orbit width is much smaller than the scale length of the alpha particle source profile, the heating profile agrees with the source profile, otherwise, the heating profile canmore » be significantly broadened. It is also found that the stagnation particles move to the magnetic axis during the slowing-down process, thus the effect of stagnation orbits is not beneficial to the helium ash removal. The source profile of helium ash is broadened in comparison with the alpha source profile, which is similar to the heating profile.« less

Linking potential heat source and sink to urban heat island: Heterogeneous effects of landscape pattern on land surface temperature.

PubMed

Li, Weifeng; Cao, Qiwen; Lang, Kun; Wu, Jiansheng

2017-05-15

Rapid urbanization has significantly contributed to the development of urban heat island (UHI). Regulating landscape composition and configuration would help mitigate the UHI in megacities. Taking Shenzhen, China, as a case study area, we defined heat source and heat sink and identified strong and weak sources as well as strong and weak sinks according to the natural and socioeconomic factors influencing land surface temperature (LST). Thus, the potential thermal contributions of heat source and heat sink patches were differentiated. Then, the heterogeneous effects of landscape pattern on LST were examined by using semiparametric geographically weighted regression (SGWR) models. The results showed that landscape composition has more significant effects on thermal environment than configuration. For a strong source, the percentage of patches has a positive impact on LST. Additionally, when mosaicked with some heat sink, even a small improvement in the degree of dispersion of a strong source helps to alleviate UHI. For a weak source, the percentage and density of patches have positive impacts on LST. For a strong sink, the percentage, density, and degree of aggregation of patches have negative impacts on LST. The effects of edge density and patch shape complexity vary spatially with the fragmentation of a strong sink. Similarly, the impacts of a weak sink are mainly exerted via the characteristics of percent, density, and shape complexity of patches. Copyright © 2017 Elsevier B.V. All rights reserved.

Thermal load leveling during silicon crystal growth from a melt using anisotropic materials

DOEpatents

Carlson, Frederick M.; Helenbrook, Brian T.

2016-10-11

An apparatus for growing a silicon crystal substrate comprising a heat source, an anisotropic thermal load leveling component, a crucible, and a cold plate component is disclosed. The anisotropic thermal load leveling component possesses a high thermal conductivity and may be positioned atop the heat source to be operative to even-out temperature and heat flux variations emanating from the heat source. The crucible may be operative to contain molten silicon in which the top surface of the molten silicon may be defined as a growth interface. The crucible may be substantially surrounded by the anisotropic thermal load leveling component. The cold plate component may be positioned above the crucible to be operative with the anisotropic thermal load leveling component and heat source to maintain a uniform heat flux at the growth surface of the molten silicon.

Recovery Act: Cedarville School District Retrofit of Heating and Cooling Systems with Geothermal Heat Pumps and Ground Source Water Loops

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jarrell, Mark

Cedarville School District retrofitted the heating and cooling systems in three campus areas (High School, Middle School, and Upper Elementary School) with geothermal heat pumps and ground source water loops, as a demonstration project for the effective implementation of geothermal heat pump systems and other energy efficiency and air quality improvements.

Heat source reentry vehicle design study

NASA Technical Reports Server (NTRS)

Ryan, R. L.

1971-01-01

The design details are presented of a flight-type heat source reentry vehicle and heat exchanger compatible with the isotope Brayton power conversion system. The reference reentry vehicle and heat exchanger were modified, orbital and superorbital capability was assessed, and a complete set of detail design layout drawings were provided.

Ground-Source Heat Pumps | Climate Neutral Research Campuses | NREL

Science.gov Websites

cooling requirements and heating loads. GSHPs take advantage of moderate soil temperatures available year Are ground-source heat pumps right for your campus? Are soil conditions suitable? Are heating and consider the following before undertaking an assessment or GSHP installation. Suitable Soil Conditions The

Thermoelectric power generator with intermediate loop

DOEpatents

Bell, Lon E; Crane, Douglas Todd

2013-05-21

A thermoelectric power generator is disclosed for use to generate electrical power from heat, typically waste heat. An intermediate heat transfer loop forms a part of the system to permit added control and adjustability in the system. This allows the thermoelectric power generator to more effectively and efficiently generate power in the face of dynamically varying temperatures and heat flux conditions, such as where the heat source is the exhaust of an automobile, or any other heat source with dynamic temperature and heat flux conditions.

Thermoelectric power generator with intermediate loop

DOEpatents

Bel,; Lon, E [Altadena, CA; Crane, Douglas Todd [Pasadena, CA

2009-10-27

A thermoelectric power generator is disclosed for use to generate electrical power from heat, typically waste heat. An intermediate heat transfer loop forms a part of the system to permit added control and adjustability in the system. This allows the thermoelectric power generator to more effectively and efficiently generate power in the face of dynamically varying temperatures and heat flux conditions, such as where the heat source is the exhaust of an automobile, or any other heat source with dynamic temperature and heat flux conditions.

[Compression fracture of a fragile lumbar vertebrae as a cause of low back pain].

PubMed

Ostojić, Zdenko; Ostojić, Ljerka; Pehar, Zoran; Ceramida, Meliha; Letica, Ludvih

2002-01-01

The patient felt sharp back lumbal pain while lifting heavy object in flexion position of the back. Rtg showed compressive fracture of L2. MRI showed secondary posttraumatic edema around compressive fracture of the body of L2. The compressive fracture was caused by intracorporal haemangiome of L2. After six months we had spontaneous sanation of heamgiome. Regarding to the therapy only electromagnetotherapy was used as well as programme of kinezitherapy given according to the condition of the body of L2.

Explicit Pore Pressure Material Model in Carbon-Cloth Phenolic

NASA Technical Reports Server (NTRS)

Gutierrez-Lemini, Danton; Ehle, Curt

2003-01-01

An explicit material model that uses predicted pressure in the pores of a carbon-cloth phenolic (CCP) composite has been developed. This model is intended to be used within a finite-element model to predict phenomena specific to CCP components of solid-fuel-rocket nozzles subjected to high operating temperatures and to mechanical stresses that can be great enough to cause structural failures. Phenomena that can be predicted with the help of this model include failures of specimens in restrained-thermal-growth (RTG) tests, pocketing erosion, and ply lifting

Ground Source Heat Pumps vs. Conventional HVAC: A Comparison of Economic and Environmental Costs

DTIC Science & Technology

2009-03-26

of systems are surface water heat pumps (SWHPs), ground water heat pumps (GWHPs), and ground coupled heat pumps ( GCHPs ) (Kavanaugh & Rafferty, 1997...Kavanaugh & Rafferty, 1997). Ground Coupled Heat Pumps (Closed-Loop Ground Source Heat Pumps) GCHPs , otherwise known as closed-loop GSHPs, are the...Significant confusion has arisen through the use of GCHP and closed-loop GSHP terminology. Closed-loop GSHP is the preferred nomenclature for this

Cooling technique

DOE Office of Scientific and Technical Information (OSTI.GOV)

Salamon, Todd R; Vyas, Brijesh; Kota, Krishna

An apparatus and a method are provided. Use is made of a wick structure configured to receive a liquid and generate vapor in when such wick structure is heated by heat transferred from heat sources to be cooled off. A vapor channel is provided configured to receive the vapor generated and direct said vapor away from the wick structure. In some embodiments, heat conductors are used to transfer the heat from the heat sources to the liquid in the wick structure.

Coherent vertical structures in numerical simulations of buoyant plumes from wildland fires

Treesearch

Philip Cunningham; Scott L. Goodrick; M. Yousuff Hussaini; Rodman R. Linn

2005-01-01

The structure and dynamics of buoyant plumes arising from surface-based heat sources in a vertically sheared ambient atmospheric flow are examined via simulations of a three-dimensional, compressible numerical model. Simple circular heat sources and asymmetric elliptical ring heat sources that are representative of wildland fires of moderate intensity are considered....

Recovery Act: Tennessee Energy Efficient Schools Initiative Ground Source Heat Pump Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Townsend, Terry; Slusher, Scott

The Tennessee Energy Efficient Schools Initiative (EESI) Hybrid-Water Source Heat Pump (HY-GSHP) Program sought to provide installation costs and operation costs for different Hybrid water source heat pump systems’ configurations so that other State of Tennessee School Districts will have a resource for comparison purposes if considering a geothermal system.

Radioisotopic heat source

DOEpatents

Jones, G.J.; Selle, J.E.; Teaney, P.E.

1975-09-30

Disclosed is a radioisotopic heat source and method for a long life electrical generator. The source includes plutonium dioxide shards and yttrium or hafnium in a container of tantalum-tungsten-hafnium alloy, all being in a nickel alloy outer container, and subjected to heat treatment of from about 1570$sup 0$F to about 1720$sup 0$F for about one h. (auth)

Comparison on welding mode characteristics of arc heat source for heat input control in hybrid welding of aluminum alloy

NASA Astrophysics Data System (ADS)

Song, Moo-Keun; Kim, Jong-Do; Oh, Jae-Hwan

2015-03-01

Presently in shipbuilding, transportation and aerospace industries, the potential to apply welding using laser and laser-arc hybrid heat sources is widely under research. This study has the purpose of comparing the weldability depending on the arc mode by varying the welding modes of arc heat sources in applying laser-arc hybrid welding to aluminum alloy and of implementing efficient hybrid welding while controlling heat input. In the experimental study, we found that hybrid welding using CMT mode produced deeper penetration and sounder bead surface than those characteristics produced during only laser welding, with less heat input compared to that required in pulsed arc mode.

Thulium heat source IR D Project 91-031

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walter, C.E.; Kammeraad, J.E.; Newman, J.G.

1991-01-01

The goal of the Thulium Heat Source study is to determine the performance capability and evaluate the safety and environmental aspects of a thulium-170 heat source. Thulium-170 has several attractive features, including the fact that it decays to a stable, chemically innocuous isotope in a relatively short time. A longer-range goal is to attract government funding for the development, fabrication, and demonstration testing in an Autonomous Underwater Vehicle (AUV) of one or more thulium isotope power (TIP) prototype systems. The approach is to study parametrically the performance of thulium-170 heat source designs in the power range of 5-50 kW{sub th}.more » At least three heat source designs will be characterized in this power range to assess their performance, mass, and volume. The authors will determine shielding requirements, and consider the safety and environmental aspects of their use.« less

Material impacts and heat flux characterization of an electrothermal plasma source with an applied magnetic field

NASA Astrophysics Data System (ADS)

Gebhart, T. E.; Martinez-Rodriguez, R. A.; Baylor, L. R.; Rapp, J.; Winfrey, A. L.

2017-08-01

To produce a realistic tokamak-like plasma environment in linear plasma device, a transient source is needed to deliver heat and particle fluxes similar to those seen in an edge localized mode (ELM). ELMs in future large tokamaks will deliver heat fluxes of ˜1 GW/m2 to the divertor plasma facing components at a few Hz. An electrothermal plasma source can deliver heat fluxes of this magnitude. These sources operate in an ablative arc regime which is driven by a DC capacitive discharge. An electrothermal source was configured with two pulse lengths and tested under a solenoidal magnetic field to determine the resulting impact on liner ablation, plasma parameters, and delivered heat flux. The arc travels through and ablates a boron nitride liner and strikes a tungsten plate. The tungsten target plate is analyzed for surface damage using a scanning electron microscope.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tong, Tao; Letoquin, Ronan; Keller, Bernd

An LED lamp or bulb is disclosed that comprises a light source, a heat sink structure and a remote planar phosphor carrier having at least one conversion material. The phosphor carrier can be remote to the light sources and mounted to the heat sink so that heat from the phosphor carrier spreads into the heat sink. The phosphor carrier can comprise a thermally conductive transparent material and a phosphor layer, with an LED based light source mounted to the heat sink such that light from the light source passes through the phosphor carrier. At least some of the LED lightmore » is converted by the phosphor carrier, with some lamp embodiments emitting a white light combination of LED and phosphor light. The phosphor arranged according to the present invention can operate at lower temperature to thereby operate at greater phosphor conversion efficiency and with reduced heat related damage to the phosphor.« less

What does heat tell a mosquito? Characterization of the orientation behaviour of Aedes aegypti towards heat sources.

PubMed

Zermoglio, Paula F; Robuchon, Eddy; Leonardi, María Soledad; Chandre, Fabrice; Lazzari, Claudio R

2017-07-01

The use of heat as a cue for the orientation of haematophagous insects towards hot-blooded hosts has been acknowledged for many decades. In mosquitoes, thermoreception has been studied at the molecular, physiological and behavioural levels, and the response to heat has been evaluated in multimodal contexts. However, a direct characterization of how these insects evaluate thermal sources is still lacking. In this study we characterize Aedes aegypti thermal orientation using a simple dual choice paradigm, providing direct evidence on how different attributes of heat sources affect their choice. We found that female mosquitoes, but not males, are able to discriminate among heat sources that are at ambient, host-range and deleterious temperatures when no other stimuli are present, eliciting a positive response towards host-range and an avoidance response towards deleterious temperatures. We also tested the preference of females according to the size and position of the sources. We found that females do not discriminate between heat sources of different sizes, but actively orientate towards closer sources at host temperature. Furthermore, we show that females cannot use IR radiation as an orientation cue. Orientation towards a host involves the integration of cues of different nature in distinct phases of the orientation. Although such integration might be decisive for successful encounter of the host, we show that heat alone is sufficient to elicit orientation behaviour. We discuss the performance of mosquitoes' thermal behaviour compared to other blood-sucking insects. Copyright © 2017 Elsevier Ltd. All rights reserved.

Special Important Aspects of the Thomson Effect

NASA Astrophysics Data System (ADS)

Lashkevych, Igor; Velázquez, J. E.; Titov, Oleg Yu.; Gurevich, Yuri G.

2018-06-01

A comprehensive study of the mechanisms of heating and cooling originating from an electrical current in semiconductor devices is reported. The variation in temperature associated with the Peltier effect is not related to the presence of heat sources and sinks if the heat flux is correctly determined. The Thomson effect is commonly regarded as a heat source/sink proportional to the Thomson coefficient, which is added to the Joule heating. In the present work, we will show that this formulation of the Thomson effect is not sufficiently clear. When the heat flux is correctly defined, the Thomson heat source/sink is proportional to the Seebeck coefficient. In the conditions in which the Peltier effect takes place, the temperature gradient is created, and, consequently, the Thomson effect will occur naturally.

Special Important Aspects of the Thomson Effect

NASA Astrophysics Data System (ADS)

Lashkevych, Igor; Velázquez, J. E.; Titov, Oleg Yu.; Gurevich, Yuri G.

2018-03-01

A comprehensive study of the mechanisms of heating and cooling originating from an electrical current in semiconductor devices is reported. The variation in temperature associated with the Peltier effect is not related to the presence of heat sources and sinks if the heat flux is correctly determined. The Thomson effect is commonly regarded as a heat source/sink proportional to the Thomson coefficient, which is added to the Joule heating. In the present work, we will show that this formulation of the Thomson effect is not sufficiently clear. When the heat flux is correctly defined, the Thomson heat source/sink is proportional to the Seebeck coefficient. In the conditions in which the Peltier effect takes place, the temperature gradient is created, and, consequently, the Thomson effect will occur naturally.

Effect of heat shock on the fatty acid and protein profiles of Cronobacter sakazakii BCRC 13988 as well as its growth and survival in the presence of various carbon, nitrogen sources and disinfectants.

PubMed

Li, Po-Ting; Hsiao, Wan-Ling; Yu, Roch-Chui; Chou, Cheng-Chun

2013-12-01

In the present study, Cronobacter sakazakii, a foodborne pathogen, was first subjected to heat shock at 47 °C for 15 min. Effect of heat shock on the fatty acid and protein profiles, carbon and nitrogen source requirements as well as the susceptibilities of C. sakazakii to Clidox-S, a chlorine-containing disinfectant and Quatricide, a quaternary ammonium compound were investigated. Results revealed that heat shock increased the proportion of myristic acid (14:0), palmitic acid (16:0) and the ratio of saturated fatty acid to unsaturated fatty acid, while reducing the proportion of palmitoleic acid (16:1) and cis-vacceric acid (18:1). In addition, eleven proteins showed enhanced expression, while one protein showed decreased expression in the heat-shocked compared to the non-heat-shocked cells. Non-heat-shocked cells in the medium supplemented with beef extract exhibited the highest maximum population. On the contrary, the highest maximum population of heat-shocked C. sakazakii was noted in the medium having either tryptone or yeast extract as the nitrogen source. Among the various carbon sources examined, the growth of the test organism, regardless of heat shock, was greatest in the medium having glucose as the carbon source. Furthermore, heat shock enhanced the resistance of C. sakazakii to Clidox-S or Quatricide. Copyright © 2013 Elsevier Ltd. All rights reserved.

10 CFR Appendix E to Subpart B of... - Uniform Test Method for Measuring the Energy Consumption of Water Heaters

Code of Federal Regulations, 2010 CFR

2010-01-01

... Heater means a water heater that uses electricity as the energy source, is designed to heat and store... that uses gas as the energy source, is designed to heat and store water at a thermostatically... energy source, is designed to heat and store water at a thermostatically controlled temperature of less...

10 CFR Appendix E to Subpart B of... - Uniform Test Method for Measuring the Energy Consumption of Water Heaters

Code of Federal Regulations, 2011 CFR

2011-01-01

... Heater means a water heater that uses electricity as the energy source, is designed to heat and store... that uses gas as the energy source, is designed to heat and store water at a thermostatically... energy source, is designed to heat and store water at a thermostatically controlled temperature of less...

10 CFR Appendix E to Subpart B of... - Uniform Test Method for Measuring the Energy Consumption of Water Heaters

Code of Federal Regulations, 2013 CFR

2013-01-01

... Heater means a water heater that uses electricity as the energy source, is designed to heat and store... that uses gas as the energy source, is designed to heat and store water at a thermostatically... energy source, is designed to heat and store water at a thermostatically controlled temperature of less...

Numerical Study on Natural Vacuum Solar Desalination System with Varying Heat Source Temperature

NASA Astrophysics Data System (ADS)

Ambarita, H.

2017-03-01

A natural vacuum desalination unit with varying low grade heat source temperature is investigated numerically. The objective is to explore the effects of the variable temperature of the low grade heat source on performances and characteristics of the desalination unit. The specifications of the desalination unit are naturally vacuumed with surface area of seawater in evaporator and heating coil are 0.2 m2 and 0.188 m2, respectively. Temperature of the heating coil is simulated based on the solar radiation in the Medan city. A program to solve the governing equations in forward time step marching technique is developed. Temperature of the evaporator, fresh water production rate, and thermal efficiency of the desalination unit are analysed. Simulation is performed for 9 hours, it starts from 8.00 and finishes at 17.00 of local time. The results show that, the desalination unit with operation time of 9 hours can produce 5.705 L of freshwater and thermal efficiency is 81.8 %. This reveals that varying temperature of the heat source of natural vacuum desalination unit shows better performance in comparison with constant temperature of the heat source.

Ground Source Geothermal District Heating and Cooling System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lowe, James William

2016-10-21

Ball State University converted its campus from a coal-fired steam boiler district heating system to a ground source heat pump geothermal district system that produces simultaneously hot water for heating and chilled water for cooling. This system will include the installation of 3,600 four hundred feet deep vertical closed loop boreholes making it the largest ground source geothermal district system in the country. The boreholes will act as heat exchangers and transfer heat by virtue of the earth’s ability to maintain an average temperature of 55 degree Fahrenheit. With growing international concern for global warming and the need to reducemore » worldwide carbon dioxide loading of the atmosphere geothermal is poised to provide the means to help reduce carbon dioxide emissions. The shift from burning coal to utilizing ground source geothermal will increase electrical consumption but an overall decrease in energy use and reduction in carbon dioxide output will be achieved. This achievement is a result of coupling the ground source geothermal boreholes with large heat pump chiller technology. The system provides the thermodynamic means to move large amounts of energy with limited energy input. Ball State University: http://cms.bsu.edu/About/Geothermal.aspx« less

Analysis and comparison of methods for the preparation of domestic hot water from district heating system, selected renewable and non-renewable sources in low-energy buildings

NASA Astrophysics Data System (ADS)

Knapik, Maciej

2018-02-01

The article presents an economic analysis and comparison of selected (district heating, natural gas, heat pump with renewable energy sources) methods for the preparation of domestic hot water in a building with low energy demand. In buildings of this type increased demand of energy for domestic hot water preparation in relation to the total energy demand can be observed. As a result, the proposed solutions allow to further lower energy demand by using the renewable energy sources. This article presents the results of numerical analysis and calculations performed mainly in MATLAB software, based on typical meteorological years. The results showed that system with heat pump and renewable energy sources Is comparable with district heating system.

An Electrothermal Plasma Source Developed for Simulation of Transient Heat Loads in Future Large Fusion Devices

NASA Astrophysics Data System (ADS)

Gebhart, Trey; Baylor, Larry; Winfrey, Leigh

2016-10-01

The realization of fusion energy requires materials that can withstand high heat and particle fluxes at the plasma material interface. In this work, an electrothermal (ET) plasma source has been designed as a possible transient heat flux source for a linear plasma material interaction device. An ET plasma source operates in the ablative arc regime, which is driven by a DC capacitive discharge. The current travels through the 4mm bore of a boron nitride liner and subsequently ablates and ionizes the liner material. This results in a high density plasma with a large unidirectional bulk flow out of the source exit. The pulse length for the ET source has been optimized using a pulse forming network to have a duration of 1ms at full-width half maximum. The peak currents and maximum source energies seen in this system are 2kA and 5kJ. The goal of this work is to show that the ET source produces electron densities and heat fluxes that are comparable to transient events in future large magnetic confinement fusion devices. Heat flux, plasma temperature, and plasma density were determined for each test shot using infrared imaging and optical spectroscopy techniques. This work will compare the ET source output (heat flux, temperature, and density) with and without an applied magnetic field. Research sponsored by the Laboratory Directed Research and Development Program of Oak Ridge National Laboratory, managed by UT-Battelle, LLC, for the U. S. Department of Energy.

Lighting system with heat distribution face plate

DOEpatents

Arik, Mehmet; Weaver, Stanton Earl; Stecher, Thomas Elliot; Kuenzler, Glenn Howard; Wolfe, Jr., Charles Franklin; Li, Ri

2013-09-10

Lighting systems having a light source and a thermal management system are provided. The thermal management system includes synthetic jet devices, a heat sink and a heat distribution face plate. The synthetic jet devices are arranged in parallel to one and other and are configured to actively cool the lighting system. The heat distribution face plate is configured to radially transfer heat from the light source into the ambient air.

Heat recovery system employing a temperature controlled variable speed fan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, W.T.

1986-05-20

A heat recovery system is described for use in recovering heat from an industrial process producing a heated fluid comprising: a source of inlet air; a housing coupled to the source and including a heat exchanger; means for passing the heated fluid through the heat exchanger; the housing including means for moving a variable volume of air adjustable over a continuous range from the source through the heat exchanger; air discharge means communicating with the housing for discharging air which has passed through the heat exchanger; a control system including first temperature sensing means for sensing the discharge temperature ofmore » the discharge air moving through the discharge means and a control circuit coupled to the first temperature sensing means and to the moving means for varying the volume of air moved in response to the sensed discharge temperature to control the temperature of discharge air passing through the discharge means at a first predetermined value; and the control system including second temperature sensing means for sensing the temperature of the source of inlet air and valve means coupled to and controlled by the control circuit to cause liquid to bypass the heat exchanger when the inlet air temperature rises above a second predetermined value.« less

Self-contained small utility system

DOEpatents

Labinov, Solomon D.; Sand, James R.

1995-01-01

A method and apparatus is disclosed to provide a fuel efficient source of readily converted energy to an isolated or remote energy consumption facility. External heat from any of a large variety of sources is converted to an electrical, mechanical, heat or cooling form of energy. A polyatomic working fluid energized by external heat sources is dissociated to a higher gaseous energy state for expansion through a turbine prime mover. The working fluid discharge from the turbine prime mover is routed to a recouperative heat exchanger for exothermic recombination reaction heat transfer to working fluid discharged from the compressor segment of the thermodynaic cycle discharge. The heated compressor discharge fluid is thereafter further heated by the external heat source to the initial higher energy state. Under the pressure at the turbine outlet, the working fluid goes out from a recouperative heat exchanger to a superheated vapor heat exchanger where it is cooled by ambient medium down to an initial temperature of condensation. Thereafter, the working fluid is condensed to a complete liquid state in a condenser cooled by an external medium. This liquid is expanded isenthalpically down to the lowest pressure of the cycle. Under this pressure, the working fluid is evaporated to the superheated vapor state of the inlet of a compressor.

Radiogenic heat production in sedimentary rocks of the Gulf of Mexico Basin, south Texas

USGS Publications Warehouse

McKenna, T.E.; Sharp, J.M.

1998-01-01

Radiogenic heat production within the sedimentary section of the Gulf of Mexico basin is a significant source of heat. Radiogenic heat should be included in thermal models of this basin (and perhaps other sedimentary basins). We calculate that radiogenic heat may contribute up to 26% of the overall surface heat-flow density for an area in south Texas. Based on measurements of the radioactive decay rate of ??-particles, potassium concentration, and bulk density, we calculate radiogenic heat production for Stuart City (Lower Cretaceous) limestones, Wilcox (Eocene) sandstones and mudrocks, and Frio (Oligocene) sandstones and mudrocks from south Texas. Heat production rates range from a low of 0.07 ?? 0.01 ??W/m3 in clean Stuart City limestones to 2.21 ?? 0.24??W/m3 in Frio mudrocks. Mean heat production rates for Wilcox sandstones, Frio sandstones, Wilcox mudrocks, and Frio mudrocks are 0.88, 1.19, 1.50, and 1.72 ??W/m3, respectively. In general, the mudrocks produce about 30-40% more heat than stratigraphically equivalent sandstones. Frio rocks produce about 15% more heat than Wilcox rocks per unit volume of clastic rock (sandstone/mudrock). A one-dimensional heat-conduction model indicates that this radiogenic heat source has a significant effect on subsurface temperatures. If a thermal model were calibrated to observed temperatures by optimizing basal heat-flow density and ignoring sediment heat production, the extrapolated present-day temperature of a deeply buried source rock would be overestimated.Radiogenic heat production within the sedimentary section of the Gulf of Mexico basin is a significant source of heat. Radiogenic heat should be included in thermal models of this basin (and perhaps other sedimentary basins). We calculate that radiogenic heat may contribute up to 26% of the overall surface heat-flow density for an area in south Texas. Based on measurements of the radioactive decay rate of ??-particles, potassium concentration, and bulk density, we calculate radiogenic heat production for Stuart City (Lower Cretaceous) limestones, Wilcox (Eocene) sandstones and mudrocks, and Frio (Oligocene) sandstones and mudrocks from south Texas. Heat production rates range from a low of 0.07??0.01 ??W/m3 in clean Stuart City limestones to 2.21??0.24 ??W/m3 in Frio mudrocks. Mean heat production rates for Wilcox sandstones, Frio sandstones, Wilcox mudrocks, and Frio mudrocks are 0.88, 1.19, 1.50, and 1.72 ??W/m3, respectively. In general, the mudrocks produce about 30-40% more heat than stratigraphically equivalent sandstones. Frio rocks produce about 15% more heat than Wilcox rocks per unit volume of clastic rock (sandstone/mudrock). A one-dimensional heat-conduction model indicates that this radiogenic heat source has a significant effect on subsurface temperatures. If a thermal model were calibrated to observed temperatures by optimizing basal heat-flow density and ignoring sediment heat production, the extrapolated present-day temperature of a deeply buried source rock would be overestimated.

Prospects for development of heat supply systems in high-rise districts

NASA Astrophysics Data System (ADS)

Zhila, Viktor; Solovyeva, Elena

2018-03-01

The article analyzes the main advantages and disadvantages of centralized and decentralized heat supply systems in high-rise districts. The main schemes of centralized heat supply systems are considered. They include centralized heat supply from boiler houses, centralized heat supply from autonomous heat sources, heat supply from roof boiler houses and door-to-door heating supply. For each of these variant, the gas distribution systems are considered and analyzed. These systems vary depending on the heat source location. For each of these systems, technical and economic indicators are taken into account, the analysis of which allows choosing the best option for districts where high-rise buildings predominate.

Plasma-catalyzed fuel reformer

DOEpatents

Hartvigsen, Joseph J.; Elangovan, S.; Czernichowski, Piotr; Hollist, Michele

2013-06-11

A reformer is disclosed that includes a plasma zone to receive a pre-heated mixture of reactants and ionize the reactants by applying an electrical potential thereto. A first thermally conductive surface surrounds the plasma zone and is configured to transfer heat from an external heat source into the plasma zone. The reformer further includes a reaction zone to chemically transform the ionized reactants into synthesis gas comprising hydrogen and carbon monoxide. A second thermally conductive surface surrounds the reaction zone and is configured to transfer heat from the external heat source into the reaction zone. The first thermally conductive surface and second thermally conductive surface are both directly exposed to the external heat source. A corresponding method and system are also disclosed and claimed herein.

The efficiency of the heat pump water heater, during DHW tapping cycle

NASA Astrophysics Data System (ADS)

Gużda, Arkadiusz; Szmolke, Norbert

2017-10-01

This paper discusses one of the most effective systems for domestic hot water (DHW) production based on air-source heat pump with an integrated tank. The operating principle of the heat pump is described in detail. Moreover, there is an account of experimental set-up and results of the measurements. In the experimental part, measurements were conducted with the aim of determining the energy parameters and measures of the economic efficiency related to the presented solution. The measurements that were conducted are based on the tapping cycle that is similar to the recommended one in EN-16147 standard. The efficiency of the air source heat pump during the duration of the experiment was 2.43. In the end of paper, authors conducted a simplified ecological analysis in order to determine the influence of operation of air-source heat pump with integrated tank on the environment. Moreover the compression with the different source of energy (gas boiler with closed combustion chamber and boiler fired by the coal) was conducted. The heat pump is the ecological friendly source of the energy.

Pyrotechnic device provides one-shot heat source

NASA Technical Reports Server (NTRS)

Haller, H. C.; Lalli, V. R.

1968-01-01

Pyrotechnic heater provides a one-shot heat source capable of creating a predetermined temperature around sealed packages. It is composed of a blend of an active chemical element and another compound which reacts exothermically when ignited and produces fixed quantities of heat.

Individualized supervised resistance training during nebulization in adults with cystic fibrosis.

PubMed

Shaw, Ina; Kinsey, Janine E; Richards, Roxanne; Shaw, Brandon S

2016-01-01

Since dyspnea limits exercise adherence and intensity in cystic fibrosis (CF) patients, engaging in resistance training (RT), which causes less dyspnea than other exercise modalities, while using nebulizers could not only overcome this barrier, but also enhance long-term adaptations to treatment. The objective of this study was to examine the effects of RT during nebulization on spirometry, anthropometry, chest wall excursion, respiratory muscle strength and health-related quality of life (HRQOL). Fourteen male and female CF patients were assigned to a four-week, 20-minute, 5-day per week proof-of-concept RT group (RTG) (n=7) or non-exercising control group (CON) (n=7), with 3 CON patients later dropping out of the study. Patients performed whole body exercises for 3 sets of 10 reps using resistance bands, since such bands have previously demonstrated a greater effect on functional exercise capacity than conventional RT in lung patients. The RTG displayed significant (p≤0.05) increases in FEV 1 , FEV 1 /FVC, latissimusdorsi strength, pectoralis major clavicular portion strength, pectoralis major sternocostal portion strength and emotional and digestion HRQOL domains, while decreasing pectoralis minor strength on the left and social, body image and respiration HRQOL domains. This small scale proof-of-concept investigation demonstrates the multiple and simultaneous benefits of RT during nebulization in CF patients. The improvements in pulmonary measures are particularly promising especially since this study only made use of a four-week experimental period. This study provides an important alternative, time-saving treatment for the CF patient that does not add to the treatment burden of CF patients.

Effects of two programs of exercise on body composition of adolescents with Down syndrome

PubMed Central

Seron, Bruna Barboza; Silva, Renan Alvarenga C.; Greguol, Márcia

2014-01-01

Objective: To investigate the effects of a 12 week aerobic and resistance exercise on body composition of adolescents with Down syndrome. Methods: A quasi-experimental study with 41 adolescents with Down syndrome, aged 15.5±2.7 years, divided into three groups: Aerobic Training Group (ATG; n=16), Resisted Training Group (RTG; n=15) and Control Group (CG; n=10). There were two types of training: aerobic, with intensity of 50-70% of the heart rate reserve 3 times/week, and resisted, with intensity of 12 maximum repetitions 2 times week. Both trainings were applied during a 12-week period. The percentage of fat evaluation was performed using plethysmography with Bod Pod(r) equipment. Waist circumference (WC), body weight and height were also measured. Paired t-test was used to compare variables before and after the exercise program. Results: The percentage of body fat did not change significantly for both groups that participated in the training intervention. However, CG showed a significant increase in this variable (31.3±7.2 versus 34.0±7.9). On the other hand, body mass index (BMI) and WC were significantly reduced for ATG (BMI: 27.0±4.4 and 26.5±4.2; WC: 87.3±11.1 and 86.2±9.7), while RTG and GC showed no differences in these variables. Conclusions: The aerobic and resisted training programs maintained body fat levels. ATG significantly reduced BMI and WC measures. Individuals who did not attend the training intervention increased their percentage of fat. PMID:24676196

49 CFR Appendix B to Part 238 - Test Methods and Performance Criteria for the Flammability and Smoke Emission Characteristics of...

Code of Federal Regulations, 2012 CFR

2012-10-01

... Flammability of Flexible Cellular Materials Using a Radiant Heat Energy Source. (v) ASTM E 119-00a, Standard... Method for Surface Flammability of Materials Using a Radiant Heat Energy Source. (vii) ASTM E 648-00, Standard Test Method for Critical Radiant Flux of Floor-Covering Systems Using a Radiant Heat Energy Source...

49 CFR Appendix B to Part 238 - Test Methods and Performance Criteria for the Flammability and Smoke Emission Characteristics of...

Code of Federal Regulations, 2013 CFR

2013-10-01

... Flammability of Flexible Cellular Materials Using a Radiant Heat Energy Source. (v) ASTM E 119-00a, Standard... Method for Surface Flammability of Materials Using a Radiant Heat Energy Source. (vii) ASTM E 648-00, Standard Test Method for Critical Radiant Flux of Floor-Covering Systems Using a Radiant Heat Energy Source...

49 CFR Appendix B to Part 238 - Test Methods and Performance Criteria for the Flammability and Smoke Emission Characteristics of...

Code of Federal Regulations, 2011 CFR

2011-10-01

... Flammability of Flexible Cellular Materials Using a Radiant Heat Energy Source. (v) ASTM E 119-00a, Standard... Method for Surface Flammability of Materials Using a Radiant Heat Energy Source. (vii) ASTM E 648-00, Standard Test Method for Critical Radiant Flux of Floor-Covering Systems Using a Radiant Heat Energy Source...

49 CFR Appendix B to Part 238 - Test Methods and Performance Criteria for the Flammability and Smoke Emission Characteristics of...

Code of Federal Regulations, 2014 CFR

2014-10-01

... Flammability of Flexible Cellular Materials Using a Radiant Heat Energy Source. (v) ASTM E 119-00a, Standard... Method for Surface Flammability of Materials Using a Radiant Heat Energy Source. (vii) ASTM E 648-00, Standard Test Method for Critical Radiant Flux of Floor-Covering Systems Using a Radiant Heat Energy Source...

Consideration of Thermoelectric Power Generation by Using Hot Spring Thermal Energy or Industrial Waste Heat

NASA Astrophysics Data System (ADS)

Sasaki, Keiichi; Horikawa, Daisuke; Goto, Koichi

2015-01-01

Today, we face some significant environmental and energy problems such as global warming, urban heat island, and the precarious balance of world oil supply and demand. However, we have not yet found a satisfactory solution to these problems. Waste heat recovery is considered to be one of the best solutions because it can improve energy efficiency by converting heat exhausted from plants and machinery to electric power. This technology would also prevent atmospheric temperature increases caused by waste heat, and decrease fossil fuel consumption by recovering heat energy, thus also reducing CO2 emissions. The system proposed in this research generates electric power by providing waste heat or unharnessed thermal energy to built-in thermoelectric modules that can convert heat into electric power. Waste heat can be recovered from many places, including machinery in industrial plants, piping in electric power plants, waste incineration plants, and so on. Some natural heat sources such as hot springs and solar heat can also be used for this thermoelectric generation system. The generated power is expected to be supplied to auxiliary machinery around the heat source, stored as an emergency power supply, and so on. The attributes of this system are (1) direct power generation using hot springs or waste heat; (2) 24-h stable power generation; (3) stand-alone power system with no noise and no vibration; and (4) easy maintenance attributed to its simple structure with no moving parts. In order to maximize energy use efficiency, the temperature difference between both sides of the thermoelectric (TE) modules built into the system need to be kept as large as possible. This means it is important to reduce thermal resistance between TE modules and heat source. Moreover, the system's efficiency greatly depends on the base temperature of the heat sources and the material of the system's TE modules. Therefore, in order to make this system practical and efficient, it is necessary to choose the heat source first and then design the most appropriate structure for the source by applying analytical methods. This report describes how to design a prototype of a thermoelectric power generator using the analytical approach and the results of performance evaluation tests carried out in the field.

Effect of Inverter Power Source Characteristics on Welding Stability and Heat Affected Zone Dimensions

NASA Astrophysics Data System (ADS)

Il'yaschenko, D. P.; Chinakhov, D. A.; Mamadaliev, R. A.

2018-01-01

The paper presents results the research in the effect of power sources dynamic characteristics on stability of melting and electrode metal transfer to the weld pool shielded metal arc welding. It is proved that when applying inverter-type welding power sources, heat and mass transfer characteristics change, arc gap short-circuit time and drop generation time are reduced. This leads to reduction of weld pool heat content and contraction of the heat-affected zone by 36% in comparison the same parameters obtained using a diode rectifier.

Thulium-170 heat source

DOEpatents

Walter, Carl E.; Van Konynenburg, Richard; VanSant, James H.

1992-01-01

An isotopic heat source is formed using stacks of thin individual layers of a refractory isotopic fuel, preferably thulium oxide, alternating with layers of a low atomic weight diluent, preferably graphite. The graphite serves several functions: to act as a moderator during neutron irradiation, to minimize bremsstrahlung radiation, and to facilitate heat transfer. The fuel stacks are inserted into a heat block, which is encased in a sealed, insulated and shielded structural container. Heat pipes are inserted in the heat block and contain a working fluid. The heat pipe working fluid transfers heat from the heat block to a heat exchanger for power conversion. Single phase gas pressure controls the flow of the working fluid for maximum heat exchange and to provide passive cooling.

X-Ray Source Heights in a Solar Flare: Thick-Target Versus Thermal Conduction Front Heating

NASA Technical Reports Server (NTRS)

Reep, J. W.; Bradshaw, S. J.; Holman, G. D.

2016-01-01

Observations of solar flares with RHESSI have shown X-ray sources traveling along flaring loops, from the corona down to the chromosphere and back up. The 2002 November 28 C1.1 flare, first observed with RHESSI by Sui et al. and quantitatively analyzed by O'Flannagain et al., very clearly shows this behavior. By employing numerical experiments, we use these observations of X-ray source height motions as a constraint to distinguish between heating due to a non-thermal electron beam and in situ energy deposition in the corona. We find that both heating scenarios can reproduce the observed light curves, but our results favor non-thermal heating. In situ heating is inconsistent with the observed X-ray source morphology and always gives a height dispersion with photon energy opposite to what is observed.

Seasonal and interannual variability of atmospheric heat sources and moisture sinks as determined from NCEP/NCAR ranalysis. Part I

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yanai, Michio; Tomita, Tomohiko

1997-11-01

In this paper, an analysis of the heat and moisture budgets of the troposphere is revised and extended. The analysis is based on the National Centers for Environmental Prediction (NCEP) and National Center for Atmospheric Research (NCAR) reanalysis from 1980 to 1994. The seasonal and interannual variability of heat sources and sinks and the nature of heating over various geographical locations is examined in detail. Results presented include global distributions of the 15-year mean of the vertically integrated heat source and moisture sink and the outgoing longwave radiation flux for northern winter and northern summer. A time series of monthlymore » mean anomalies of the apparent heat source, the apparent moisture sink, outgoing longwave radiation, sea surface temperature, and divergence at wind fields of 850 hPa and 200 hPa are presented for the equatorial Indian Ocean, the equatorial eastern Pacific Ocean, western Tibet, and eastern Tibet. In the equatorial Indian Ocean, short period oscillation is superimposed upon longer periods. Over the eastern Pacific, a longer periodicity is dominant and the variability of the heat source is very well correlated with similar variations of outgoing longwave radiation, sea surface temperature, and horizontal divergence. The high correlation with these variables suggests that anomalous heating is accompanied by intensified convective activity favored by warmer sea surface temperature. 13 refs., 5 figs.« less

Estimation of the effective heating systems radius as a method of the reliability improving and energy efficiency

NASA Astrophysics Data System (ADS)

Akhmetova, I. G.; Chichirova, N. D.

2017-11-01

When conducting an energy survey of heat supply enterprise operating several boilers located not far from each other, it is advisable to assess the degree of heat supply efficiency from individual boiler, the possibility of energy consumption reducing in the whole enterprise by switching consumers to a more efficient source, to close in effective boilers. It is necessary to consider the temporal dynamics of perspective load connection, conditions in the market changes. To solve this problem the radius calculation of the effective heat supply from the thermal energy source can be used. The disadvantage of existing methods is the high complexity, the need to collect large amounts of source data and conduct a significant amount of computational efforts. When conducting an energy survey of heat supply enterprise operating a large number of thermal energy sources, rapid assessment of the magnitude of the effective heating radius requires. Taking into account the specifics of conduct and objectives of the energy survey method of calculation of effective heating systems radius, to use while conducting the energy audit should be based on data available heat supply organization in open access, minimize efforts, but the result should be to match the results obtained by other methods. To determine the efficiency radius of Kazan heat supply system were determined share of cost for generation and transmission of thermal energy, capital investment to connect new consumers. The result were compared with the values obtained with the previously known methods. The suggested Express-method allows to determine the effective radius of the centralized heat supply from heat sources, in conducting energy audits with the effort minimum and the required accuracy.

Heat pipe array heat exchanger

DOEpatents

Reimann, Robert C.

1987-08-25

A heat pipe arrangement for exchanging heat between two different temperature fluids. The heat pipe arrangement is in a ounterflow relationship to increase the efficiency of the coupling of the heat from a heat source to a heat sink.

Material impacts and heat flux characterization of an electrothermal plasma source with an applied magnetic field

DOE PAGES

Gebhart, T. E.; Martinez-Rodriguez, R. A.; Baylor, L. R.; ...

2017-08-11

To produce a realistic tokamak-like plasma environment in linear plasma device, a transient source is needed to deliver heat and particle fluxes similar to those seen in an edge localized mode (ELM). ELMs in future large tokamaks will deliver heat fluxes of ~1 GW/m 2 to the divertor plasma facing components at a few Hz. An electrothermal plasma source can deliver heat fluxes of this magnitude. These sources operate in an ablative arc regime which is driven by a DC capacitive discharge. An electrothermal source was configured in this paper with two pulse lengths and tested under a solenoidal magneticmore » field to determine the resulting impact on liner ablation, plasma parameters, and delivered heat flux. The arc travels through and ablates a boron nitride liner and strikes a tungsten plate. Finally, the tungsten target plate is analyzed for surface damage using a scanning electron microscope.« less

Material impacts and heat flux characterization of an electrothermal plasma source with an applied magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gebhart, T. E.; Martinez-Rodriguez, R. A.; Baylor, L. R.

To produce a realistic tokamak-like plasma environment in linear plasma device, a transient source is needed to deliver heat and particle fluxes similar to those seen in an edge localized mode (ELM). ELMs in future large tokamaks will deliver heat fluxes of ~1 GW/m 2 to the divertor plasma facing components at a few Hz. An electrothermal plasma source can deliver heat fluxes of this magnitude. These sources operate in an ablative arc regime which is driven by a DC capacitive discharge. An electrothermal source was configured in this paper with two pulse lengths and tested under a solenoidal magneticmore » field to determine the resulting impact on liner ablation, plasma parameters, and delivered heat flux. The arc travels through and ablates a boron nitride liner and strikes a tungsten plate. Finally, the tungsten target plate is analyzed for surface damage using a scanning electron microscope.« less

Hot air heat gun

NASA Astrophysics Data System (ADS)

Poston, Terry L.

1989-10-01

The invention relates generally to the art of self-contained heating devices and in particular to portable heating devices employing chemical reaction to produce heat. Currently, hand-held heat sources, capable of producing heat at a sufficiently high temperature to activate heat-shrink material, rely on either the combustion of flammable material or electrical power to provide energy for generating the required heat. An object of the present invention is to provide a portable device capable of providing sufficient heat to shrink heat-shrinkable tubing. A further object of the invention is to provide a non-flammable heat source suitable for use in the presence of explosive atmospheres. Still another object of the invention is to provide a portable hand-held device for generating heat which can be directed to a specific location on a work surface.

Improved efficiency and precise temperature control of low-frequency induction-heating pure iron vapor source on ECR ion source

NASA Astrophysics Data System (ADS)

Kato, Y.; Takenaka, T.; Yano, K.; Kiriyama, R.; Kurisu, Y.; Nozaki, D.; Muramatsu, M.; Kitagawa, A.; Uchida, T.; Yoshida, Y.; Sato, F.; Iida, T.

2012-11-01

Multiply charged ions to be used prospectively are produced from solid pure material in an electron cyclotron resonance ion source (ECRIS). Recently a pure iron source is also required for the production of caged iron ions in the fullerene in order to control cells in vivo in bio-nano science and technology. We adopt directly heating iron rod by induction heating (IH) because it has non-contact with insulated materials which are impurity gas sources. We choose molybdenum wire for the IH coils because it doesn't need water cooling. To improve power efficiency and temperature control, we propose to the new circuit without previously using the serial and parallel dummy coils (SPD) for matching and safety. We made the circuit consisted of inductively coupled coils which are thin-flat and helix shape, and which insulates the IH power source from the evaporator. This coupling coils circuit, i.e. insulated induction heating coil transformer (IHCT), can be move mechanically. The secondary current can be adjusted precisely and continuously. Heating efficiency by using the IHCT is much higher than those of previous experiments by using the SPD, because leakage flux is decreased and matching is improved simultaneously. We are able to adjust the temperature in heating the vapor source around melting point. And then the vapor pressure can be controlled precisely by using the IHCT. We can control ±10K around 1500°C by this method, and also recognize to controlling iron vapor flux experimentally in the extreme low pressures. Now we come into next stage of developing induction heating vapor source for materials with furthermore high temperature melting points above 2000K with the IHCT, and then apply it in our ECRIS.

Experimental investigation on water quality standard of Yangtze River water source heat pump.

PubMed

Qin, Zenghu; Tong, Mingwei; Kun, Lin

2012-01-01

Due to the surface water in the upper reaches of Yangtze River in China containing large amounts of silt and algae, high content of microorganisms and suspended solids, the water in Yangtze River cannot be used for cooling a heat pump directly. In this paper, the possibility of using Yangtze River, which goes through Chongqing, a city in southwest China, as a heat source-sink was investigated. Water temperature and quality of the Yangtze River in the Chongqing area were analyzed and the performance of water source heat pump units in different sediment concentrations, turbidity and algae material conditions were tested experimentally, and the water quality standards, in particular surface water conditions, in the Yangtze River region that adapt to energy-efficient heat pumps were also proposed. The experimental results show that the coefficient of performance heat pump falls by 3.73% to the greatest extent, and the fouling resistance of cooling water in the heat exchanger increases up to 25.6% in different water conditions. When the sediment concentration and the turbidity in the river water are no more than 100 g/m3 and 50 NTU respectively, the performance of the heat pump is better, which can be used as a suitable river water quality standard for river water source heat pumps.

Cogeneration technology alternatives study. Volume 4: Heat Sources, balance of plant and auxiliary systems

NASA Technical Reports Server (NTRS)

1980-01-01

Data and information established for heat sources balance of plant items, thermal energy storage, and heat pumps are presented. Design case descriptions are given along with projected performance values. Capital cost estimates for representative cogeneration plants are also presented.

Heat transfer to four fineness-ratio-1.6 hexagonal prisms with various corner radii at Mach 6

NASA Technical Reports Server (NTRS)

Hunt, J. L.

1972-01-01

An investigation was conducted in the Langley 20-inch Mach 6 tunnel to define the aerodynamic heat transfer to the radioisotope fuel cask (heat source) of the SNAP-19/Pioneer power system. The shape of the SNAP-19/Pioneer heat source is that of a hexagonal prism with flat ends; the fineness ratio, based on maximum (edge to edge) diameter, is 1.61. Phase-change-paint heat-transfer data and schlieren photographs were obtained on four possible 1/2-scale entry configurations of the SNAP-19/Pioneer heat source. Tests were conducted over a wide range of attitudes and at nominal Reynolds numbers, based on the length of the unablated configuration, of 33,000; 84,000; and 2,200,000.

A study of high-temperature heat pipes with multiple heat sources and sinks. I - Experimental methodology and frozen startup profiles. II - Analysis of continuum transient and steady-state experimental data with numerical predictions

NASA Technical Reports Server (NTRS)

Faghri, A.; Cao, Y.; Buchko, M.

1991-01-01

Experimental profiles for heat pipe startup from the frozen state were obtained, using a high-temperature sodium/stainless steel pipe with multiple heat sources and sinks to investigate the startup behavior of the heat pipe for various heat loads and input locations, with both low and high heat rejection rates at the condensor. The experimental results of the performance characteristics for the continuum transient and steady-state operation of the heat pipe were analyzed, and the performance limits for operation with varying heat fluxes and location are determined.

The calculating study of the moisture transfer influence at the temperature field in a porous wet medium with internal heat sources

NASA Astrophysics Data System (ADS)

Kuzevanov, V. S.; Garyaev, A. B.; Zakozhurnikova, G. S.; Zakozhurnikov, S. S.

2017-11-01

A porous wet medium with solid and gaseous components, with distributed or localized heat sources was considered. The regimes of temperature changes at the heating at various initial material moisture were studied. Mathematical model was developed applied to the investigated wet porous multicomponent medium with internal heat sources, taking into account the transfer of the heat by heat conductivity with variable thermal parameters and porosity, heat transfer by radiation, chemical reactions, drying and moistening of solids, heat and mass transfer of volatile products of chemical reactions by flows filtration, transfer of moisture. The algorithm of numerical calculation and the computer program that implements the proposed mathematical model, allowing to study the dynamics of warming up at a local or distributed heat release, in particular the impact of the transfer of moisture in the medium on the temperature field were created. Graphs of temperature change were obtained at different points of the graphics with different initial moisture. Conclusions about the possible control of the regimes of heating a solid porous body by the initial moisture distribution were made.

Nonlinear Gravitational and Radiation Aspects in Nanoliquid with Exponential Space Dependent Heat Source and Variable Viscosity

NASA Astrophysics Data System (ADS)

Gireesha, B. J.; Kumar, P. B. Sampath; Mahanthesh, B.; Shehzad, S. A.; Abbasi, F. M.

2018-05-01

The nonlinear convective flow of kerosene-Alumina nanoliquid subjected to an exponential space dependent heat source and temperature dependent viscosity is investigated here. This study is focuses on augmentation of heat transport rate in liquid propellant rocket engine. The kerosene-Alumina nanoliquid is considered as the regenerative coolant. Aspects of radiation and viscous dissipation are also covered. Relevant nonlinear system is solved numerically via RK based shooting scheme. Diverse flow fields are computed and examined for distinct governing variables. We figured out that the nanoliquid's temperature increased due to space dependent heat source and radiation aspects. The heat transfer rate is higher in case of changeable viscosity than constant viscosity.

Nonlinear Gravitational and Radiation Aspects in Nanoliquid with Exponential Space Dependent Heat Source and Variable Viscosity

NASA Astrophysics Data System (ADS)

Gireesha, B. J.; Kumar, P. B. Sampath; Mahanthesh, B.; Shehzad, S. A.; Abbasi, F. M.

2018-02-01

The nonlinear convective flow of kerosene-Alumina nanoliquid subjected to an exponential space dependent heat source and temperature dependent viscosity is investigated here. This study is focuses on augmentation of heat transport rate in liquid propellant rocket engine. The kerosene-Alumina nanoliquid is considered as the regenerative coolant. Aspects of radiation and viscous dissipation are also covered. Relevant nonlinear system is solved numerically via RK based shooting scheme. Diverse flow fields are computed and examined for distinct governing variables. We figured out that the nanoliquid's temperature increased due to space dependent heat source and radiation aspects. The heat transfer rate is higher in case of changeable viscosity than constant viscosity.

Waste heat driven absorption refrigeration process and system

DOEpatents

Wilkinson, William H.

1982-01-01

Absorption cycle refrigeration processes and systems are provided which are driven by the sensible waste heat available from industrial processes and other sources. Systems are disclosed which provide a chilled water output which can be used for comfort conditioning or the like which utilize heat from sensible waste heat sources at temperatures of less than 170.degree. F. Countercurrent flow equipment is also provided to increase the efficiency of the systems and increase the utilization of available heat.

Solid State Welding Development at Marshall Space Flight Center

NASA Technical Reports Server (NTRS)

Ding, Robert J.; Walker, Bryant

2012-01-01

What is TSW and USW? TSW is a solid state weld process consisting of an induction coil heating source, a stir rod, and non-rotating containment plates Independent heating, stirring and forging controls Decouples the heating, stirring and forging process elements of FSW. USW is a solid state weld process consisting of an induction coil heating source, a stir rod, and a non-rotating containment plate; Ultrasonic energy integrated into non-rotating containment plate and stir rod; Independent heating, stirring and forging controls; Decouples the heating, stirring and forging process elements of FSW.

Modular Heat Exchanger With Integral Heat Pipe

NASA Technical Reports Server (NTRS)

Schreiber, Jeffrey G.

1992-01-01

Modular heat exchanger with integral heat pipe transports heat from source to Stirling engine. Alternative to heat exchangers depending on integrities of thousands of brazed joints, contains only 40 brazed tubes.

Air source integrated heat pump simulation model for EnergyPlus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shen, Bo; New, Joshua; Baxter, Van

An Air Source Integrated Heat Pump (AS-IHP) is an air source, multi-functional spacing conditioning unit with water heating function (WH), which can lead to great energy savings by recovering the condensing waste heat for domestic water heating. This paper summarizes development of the EnergyPlus AS-IHP model, introducing the physics, sub-models, working modes, and control logic. Based on the model, building energy simulations were conducted to demonstrate greater than 50% annual energy savings, in comparison to a baseline heat pump with electric water heater, over 10 US cities, using the EnergyPlus quick-service restaurant template building. We assessed water heating energy savingmore » potentials using AS-IHP versus both gas and electric baseline systems, and pointed out climate zones where AS-IHPs are promising. In addition, a grid integration strategy was investigated to reveal further energy saving and electricity cost reduction potentials, via increasing the water heating set point temperature during off-peak hours and using larger water tanks.« less

Performance analysis on a large scale borehole ground source heat pump in Tianjin cultural centre

NASA Astrophysics Data System (ADS)

Yin, Baoquan; Wu, Xiaoting

2018-02-01

In this paper, the temperature distribution of the geothermal field for the vertical borehole ground-coupled heat pump was tested and analysed. Besides the borehole ground-coupled heat pump, the system composed of the ice storage, heat supply network and cooling tower. According to the operation data for nearly three years, the temperature constant zone is in the ground depth of 40m -120m with a temperature gradient of about 3.0°C/100m. The temperature of the soil dropped significantly in the heating season, increased significantly in the cooling season, and reinstated in the transitional season. With the energy balance design of the heating and cooling and the existence of the soil thermal inertia, the soil temperature stayed in a relative stable range and the ground source heat pump system was operated with a relative high efficiency. The geothermal source heat pump was shown to be applicable for large scale utilization.

Pure Material Vapor Source by Induction Heating Evaporator for an Electron Cyclotron Resonance Ion Source

NASA Astrophysics Data System (ADS)

Matsui, Y.; Watanabe, T.; Satani, T.; Muramatsu, M.; Tanaka, K.; Kitagawa, A.; Yoshida, Y.; Sato, F.; Kato, Y.; Iida, T.

2008-11-01

Multiply charged iron ions are produced from solid pure material in an electron cyclotron resonance (ECR) ion source. We develop an evaporator by using induction heating with the induction coil which is made from bare molybdenum wire and surrounding the pure iron rod. We optimize the shape of induction heating coil and operation of rf power supply. We conduct experiment to investigate reproducibility and stability in the operation and heating efficiency. Induction heating evaporator produces pure material vapor, because materials directly heated by eddy currents have non-contact with insulated materials which are impurity gas sources. The power and the frequency of the induction currents range from 100 to 900 W and from 48 to 23 kHz, respectively. The working pressure is about 10-4 to 10-3 Pa. We measure temperature of iron rod and film deposition rate by depositing iron vapor to crystal oscillator. We confirm stability and reproducibility of evaporator enough to conduct experiment in ECR ion source. We can obtain required temperature of iron under maximum power of power supply. We are aiming the evaporator higher melting point material than iron.

On oscillatory magnetoconvection in a nanofluid layer in the presence of internal heat source and Soret effect

NASA Astrophysics Data System (ADS)

Khalid, Izzati Khalidah; Mokhtar, Nor Fadzillah Mohd; Bakri, Nur Amirah; Siri, Zailan; Ibrahim, Zarina Bibi; Gani, Siti Salwa Abd

2017-11-01

The onset of oscillatory magnetoconvection for an infinite horizontal nanofluid layer subjected to Soret effect and internal heat source heated from below is examined theoretically with the implementation of linear stability theory. Two important properties that are thermophoresis and Brownian motion are included in the model and three types of lower-upper bounding systems of the model: rigid-rigid, rigid-free as well as free-free boundaries are examined. Eigenvalue equations are gained from a normal mode analysis and executed using Galerkin technique. Magnetic field effect, internal heat source effect, Soret effect and other nanofluid parameters on the oscillatory convection are presented graphically. For oscillatory mode, it is found that the effect of internal heat source is quite significant for small values of the non-dimensional parameter and elevating the internal heat source speed up the onset of convection. Meanwhile, the increasing of the strength of magnetic field in a nanofluid layer reduced the rate of thermal instability and sustain the stabilization of the system. For the Soret effect, the onset of convection in the system is accelerated when the values of the Soret effect is increased.

Infant otitis media and the use of secondary heating sources.

PubMed

Pettigrew, Melinda M; Gent, Janneane F; Triche, Elizabeth W; Belanger, Kathleen D; Bracken, Michael B; Leaderer, Brian P

2004-01-01

This prospective study investigated the association of exposure to indoor secondary heating sources with otitis media and recurrent otitis media risk in infants. We enrolled mothers living in nonsmoking households and delivering babies between 1993 and 1996 in 12 Connecticut and Virginia hospitals. Biweekly telephone interviews during the first year of life assessed diagnoses from doctors' office visits and use of secondary home heating sources, air conditioner use, and day care. Otitis media episodes separated by more than 21 days were considered to be unique episodes. Recurrent otitis media was defined as 4 or more episodes of otitis media. Repeated-measures logistic regression modeling evaluated the association of kerosene heater, fireplace, or wood stove use with otitis media episodes while controlling for potential confounders. Logistic regression evaluated the relation of these secondary heating sources with recurrent otitis media. None of the secondary heating sources were associated with otitis media or with recurrent otitis media. Otitis media was associated with day care, the winter heating season, birth in the fall, white race, additional children in the home, and a maternal history of allergies in multivariate models. Recurrent otitis media was associated with day care, birth in the fall, white race, and a maternal history of allergies or asthma. We found no evidence that the intermittent use of secondary home heating sources increases the risk of otitis media or recurrent otitis media. This study confirms earlier findings regarding the importance of day care with respect to otitis media risk.

Preliminary design study of an alternate heat source assembly for a Brayton isotope power system

NASA Technical Reports Server (NTRS)

Strumpf, H. J.

1978-01-01

Results are presented for a study of the preliminary design of an alternate heat source assembly (HSA) intended for use in the Brayton isotope power system (BIPS). The BIPS converts thermal energy emitted by a radioactive heat source into electrical energy by means of a closed Brayton cycle. A heat source heat exchanger configuration was selected and optimized. The design consists of a 10 turn helically wound Hastelloy X tube. Thermal analyses were performed for various operating conditions to ensure that post impact containment shell (PICS) temperatures remain within specified limits. These limits are essentially satisfied for all modes of operation except for the emergency cooling system for which the PICS temperatures are too high. Neon was found to be the best choice for a fill gas for auxiliary cooling system operation. Low cycle fatigue life, natural frequency, and dynamic loading requirements can be met with minor modifications to the existing HSA.

Source replenishment device for vacuum deposition

DOEpatents

Hill, Ronald A.

1988-01-01

A material source replenishment device for use with a vacuum deposition apparatus. The source replenishment device comprises an intermittent motion producing gear arrangement disposed within the vacuum deposition chamber. An elongated rod having one end operably connected to the gearing arrangement is provided with a multiarmed head at the opposite end disposed adjacent the heating element of the vacuum deposition apparatus. An inverted U-shaped source material element is releasably attached to the outer end of each arm member whereby said multiarmed head is moved to locate a first of said material elements above said heating element, whereupon said multiarmed head is lowered to engage said material element with the heating element and further lowered to release said material element on the heating element. After vaporization of said material element, second and subsequent material elements may be provided to the heating element without the need for opening the vacuum deposition apparatus to the atmosphere.

Source replenishment device for vacuum deposition

DOEpatents

Hill, R.A.

1986-05-15

A material source replenishment device for use with a vacuum deposition apparatus is described. The source replenishment device comprises an intermittent motion producing gear arrangement disposed within the vacuum deposition chamber. An elongated rod having one end operably connected to the gearing arrangement is provided with a multiarmed head at the opposite end disposed adjacent the heating element of the vacuum deposition apparatus. An inverted U-shaped source material element is releasably attached to the outer end of each arm member whereby said multiarmed head is moved to locate a first of said material elements above said heating element, whereupon said multiarmed head is lowered to engage said material element with the heating element and further lowered to release said material element on the heating element. After vaporization of said material element, second and subsequent material elements may be provided to the heating element without the need for opening the vacuum deposition apparatus to the atmosphere.

Method and Apparatus for the Portable Identification of Material Thickness and Defects Using Spatially Controlled Heat Application

NASA Technical Reports Server (NTRS)

Cramer, K. Elliott (Inventor); Winfree, William P. (Inventor)

1999-01-01

A method and a portable apparatus for the nondestructive identification of defects in structures. The apparatus comprises a heat source and a thermal imager that move at a constant speed past a test surface of a structure. The thermal imager is off set at a predetermined distance from the heat source. The heat source induces a constant surface temperature. The imager follows the heat source and produces a video image of the thermal characteristics of the test surface. Material defects produce deviations from the constant surface temperature that move at the inverse of the constant speed. Thermal noise produces deviations that move at random speed. Computer averaging of the digitized thermal image data with respect to the constant speed minimizes noise and improves the signal of valid defects. The motion of thermographic equipment coupled with the high signal to noise ratio render it suitable for portable, on site analysis.

Multiple source heat pump

DOEpatents

Ecker, Amir L.

1983-01-01

A heat pump apparatus for conditioning a fluid characterized by a fluid handler and path for circulating a fluid in heat exchange relationship with a refrigerant fluid, at least three refrigerant heat exchangers, one for effecting heat exchange with the fluid, a second for effecting heat exchange with a heat exchange fluid, and a third for effecting heat exchange with ambient air; a compressor for compressing the refrigerant; at least one throttling valve connected at the inlet side of a heat exchanger in which liquid refrigerant is vaporized; a refrigerant circuit; refrigerant; a source of heat exchange fluid; heat exchange fluid circuit and pump for circulating the heat exchange fluid in heat exchange relationship with the refrigerant; and valves or switches for selecting the heat exchangers and directional flow of refrigerant therethrough for selecting a particular mode of operation. Also disclosed are a variety of embodiments, modes of operation, and schematics therefor.

Induced natural convection thermal cycling device

DOEpatents

Heung, Leung Kit [Aiken, SC

2002-08-13

A device for separating gases, especially isotopes, by thermal cycling of a separation column using a pressure vessel mounted vertically and having baffled sources for cold and heat. Coils at the top are cooled with a fluid such as liquid nitrogen. Coils at the bottom are either electrical resistance coils or a tubular heat exchange. The sources are shrouded with an insulated "top hat" and simultaneously opened and closed at the outlets to cool or heat the separation column. Alternatively, the sources for cold and heat are mounted separately outside the vessel and an external loop is provided for each circuit.

Disposable Multi-Sensor Unattended Ground Sensor Systems for Detecting Personnel (Systemes de detection multi-capteurs terrestres autonome destines a detecter du personnel)

DTIC Science & Technology

2015-02-01

du personnel » (SET-158 RTG) identifient et accèdent aux technologies potentielles de détection des personnes, qui améliorent la sécurité par...croissante de systèmes de détection à distance, qui soient robustes et de haute performance afin d’assurer la surveillance et l’acquisition des ...les caméras basse et haute résolution. Dans la seconde phase, des approches de phénoménologie des capteurs et de traitement du

Design, fabricate, and provide engineering support for radiosotope thermoelectric generators for NASA'S CRHF and CASSINI missions

NASA Astrophysics Data System (ADS)

The technical progress achieved during the period 11 January through 31 March 1991 on Contract DE-AC03-91SF18852.000 Radioisotope Thermoelectric Generators and ancillary activities is described. The system contract consists of the following tasks: (1) Spacecraft Integration and Liaison; (2) Engineering Support; (3) Safety; (4) Qualify Unicouple Fabrication; (5) ETG Fabrication, Assembly and Test; (6) GSE; (7) RTG Shipping and Launch Support; (8) Designs, Reviews, and Mission Applications; (9) Project Management, Quality Assurance and Reliability; and (10) CAGO Acquisition (Capital Funds). The progress achieved is broken down into these tasks.

A Comparison of the Performance Capabilities of Radioisotope Energy Conversion Systems, Betavoltaic Cells, and other Nuclear Batteries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steinfelds, Eric V; Prelas, Mark A.; Sudarshan, Loyalka K.

2006-07-01

In this paper we compare the potential performance capabilities of several types of nuclear batteries to the Radioisotope Thermocouple Generators (RTG's) currently in use. There have been theoretical evaluations of, and some experimental testing of, several types of nuclear batteries including Radioisotope Energy Conversion Systems (RECS), Direct Energy Conversion (DEC) systems, and Betavoltaic Power Cells (BPC's). It has been theoretically shown, and to some extent experimentally demonstrated, that RECS, capacitive DEC systems, and possibly BPC's are all potentially capable of efficiencies well above the 9% maximum efficiency demonstrated to date in RTG's customized for deep space probe applications. Even thoughmore » RTG's have proven their reliability and have respectable power to mass ratios, it is desirable to attain efficiencies of at least 25% in typical applications. High fuel efficiency is needed to minimize the quantities of radioisotopic or nuclear fuels in the systems, to maximize power to mass ratios, and to minimize housing requirements. It has been shown that RECS can attain electric power generation efficiencies greater than 18% for devices which use Sr-90 fuel and where the accompanying material is less than roughly twice the mass of the Sr-90 fuel. Other radioisotopic fuels such as Pu-238 or Kr-85 can also be placed into RECS in order to attain efficiencies over 18%. With the likely exception of one fuel investigated by the authors, all of the promising candidates for RECS fuels can attain electric power to mass ratios greater than 15 W kg{sup -1}. It has been claimed recently [1] that the efficiency of tritium-fueled BPC's can be as high as 25%. While this is impressive and tritium has the benefit of being a 'soft' radioisotopic fuel, the silicon wafer that holds the tritium would have to be considerably more massive than the tritium contained within it and immediately adjacent to the wafer. Considering realistic mass requirements for the presence of silicon in the bulk of the wafer, a tritium cell would thus be limited to power to mass ratios <3 W kg{sup -1}. Even RECS designs with more energetic fuels and higher shielding burdens can attain >3 W kg{sup -1} and efficiencies exceeding 20%. Capacitive DEC systems can also offer significant benefits. With larger fuel quantities and larger dimensions, DEC systems can attain power efficiencies >50%. For small nuclear batteries of low or medium power, RECS appear highly desirable since the efficiency of a RECS does not vary with the amount of fuel present nor does it vary with temperature to any significant degree. (authors)« less

Reduced tillage and cover crops as a strategy for mitigating atmospheric CO2 increase through soil organic carbon sequestration in dry Mediterranean agroecosystems.

NASA Astrophysics Data System (ADS)

Almagro, María; Garcia-Franco, Noelia; de Vente, Joris; Boix-Fayos, Carolina; Díaz-Pereira, Elvira; Martínez-Mena, María

2016-04-01

The implementation of sustainable land management (SLM) practices in semiarid Mediterranean agroecosystems can be beneficial to maintain or enhance levels of soil organic carbon and mitigate current atmospheric CO2 increase. In this study, we assess the effects of different tillage treatments (conventional tillage (CT), reduced tillage (RT), reduced tillage combined with green manure (RTG), and no tillage (NT)) on soil CO2 efflux, aggregation and organic carbon stabilization in two semiarid organic rainfed almond (Prunus dulcis Mill., var. Ferragnes) orchards located in SE Spain Soil CO2 efflux, temperature and moisture were measured monthly between May 2012 and December 2014 (site 1), and between February 2013 and December 2014 (site 2). In site 1, soil CO2 efflux rates were also measured immediately following winter and spring tillage operations. Aboveground biomass inputs were estimated at the end of the growing season in each tillage treatment. Soil samples (0-15 cm) were collected in the rows between the trees (n=4) in October 2012. Four aggregate size classes were distinguished by sieving (large and small macroaggregates, free microaggregates, and free silt plus clay fraction), and the microaggregates occluded within macroaggregates (SMm) were isolated. Soil CO2efflux rates in all tillage treatments varied significantly during the year, following changes during the autumn, winter and early spring, or changes in soil moisture during late spring and summer. Repeated measures analyses of variance revealed that there were no significant differences in soil CO2 efflux between tillage treatments throughout the study period at both sites. Average annual values of C lost by soil respiration were slightly but not significantly higher under RT and RTG treatments (492 g C-CO2 m-2 yr-1) than under NT treatment (405 g C-CO2 m-2 yr-1) in site 1, while slightly but not significantly lower values were observed under RT and RTG treatments (468 and 439 g C-CO2 m-2 yr-1, respectively) than under CT treatment (399 g C-CO2 m-2 yr-1) in site 2. Tillage operations had a rapid but short-lived effect on soil CO2 efflux rates, with no significant influence on the annual soil CO2 emissions. The larger amounts of plant biomass incorporated into soil annually in the reduced tillage treatments compared to the conventional tillage treatment promoted soil aggregation and the physico-chemical soil organic carbon stabilization while soil CO2 emissions did not significantly increase. According to our results, reduced-tillage is strongly recommended as a beneficial SLM strategy for mitigating atmospheric CO2 increase through soil carbon sequestration and stabilization in semiarid Mediterranean agroecosystems.

Process to create simulated lunar agglutinate particles

NASA Technical Reports Server (NTRS)

Gustafson, Robert J. (Inventor); Gustafson, Marty A. (Inventor); White, Brant C. (Inventor)

2011-01-01

A method of creating simulated agglutinate particles by applying a heat source sufficient to partially melt a raw material is provided. The raw material is preferably any lunar soil simulant, crushed mineral, mixture of crushed minerals, or similar material, and the heat source creates localized heating of the raw material.

Augmented thermal bus

NASA Technical Reports Server (NTRS)

Schrage, Dean S. (Inventor)

1993-01-01

The present invention is directed to an augmented thermal bus. In the present design a plurity of thermo-electric heat pumps are used to couple a source plate to a sink plate. Each heat pump is individually controlled by a model based controller. The controller coordinates the heat pump to maintain isothermality in the source.

Augmented Thermal Bus

NASA Technical Reports Server (NTRS)

Schrage, Dean S. (Inventor)

1996-01-01

The present invention is directed to an augmented thermal bus. In the present design a plurality of thermo-electric heat pumps are used to couple a source plate to a sink plate. Each heat pump is individually controlled by a model based controller. The controller coordinates the heat pumps to maintain isothermality in the source.

Active microchannel heat exchanger

DOEpatents

Tonkovich, Anna Lee Y [Pasco, WA; Roberts, Gary L [West Richland, WA; Call, Charles J [Pasco, WA; Wegeng, Robert S [Richland, WA; Wang, Yong [Richland, WA

2001-01-01

The present invention is an active microchannel heat exchanger with an active heat source and with microchannel architecture. The microchannel heat exchanger has (a) an exothermic reaction chamber; (b) an exhaust chamber; and (c) a heat exchanger chamber in thermal contact with the exhaust chamber, wherein (d) heat from the exothermic reaction chamber is convected by an exothermic reaction exhaust through the exhaust chamber and by conduction through a containment wall to the working fluid in the heat exchanger chamber thereby raising a temperature of the working fluid. The invention is particularly useful as a liquid fuel vaporizer and/or a steam generator for fuel cell power systems, and as a heat source for sustaining endothermic chemical reactions and initiating exothermic reactions.

Method for forming synthesis gas using a plasma-catalyzed fuel reformer

DOEpatents

Hartvigsen, Joseph J; Elangovan, S; Czernichowski, Piotr; Hollist, Michele

2015-04-28

A method of forming a synthesis gas utilizing a reformer is disclosed. The method utilizes a reformer that includes a plasma zone to receive a pre-heated mixture of reactants and ionize the reactants by applying an electrical potential thereto. A first thermally conductive surface surrounds the plasma zone and is configured to transfer heat from an external heat source into the plasma zone. The reformer further includes a reaction zone to chemically transform the ionized reactants into synthesis gas comprising hydrogen and carbon monoxide. A second thermally conductive surface surrounds the reaction zone and is configured to transfer heat from the external heat source into the reaction zone. The first thermally conductive surface and second thermally conductive surface are both directly exposed to the external heat source. A corresponding apparatus and system are also disclosed herein.

Solar-powered Rankine heat pump for heating and cooling

NASA Technical Reports Server (NTRS)

Rousseau, J.

1978-01-01

The design, operation and performance of a familyy of solar heating and cooling systems are discussed. The systems feature a reversible heat pump operating with R-11 as the working fluid and using a motor-driven centrifugal compressor. In the cooling mode, solar energy provides the heat source for a Rankine power loop. The system is operational with heat source temperatures ranging from 155 to 220 F; the estimated coefficient of performance is 0.7. In the heating mode, the vapor-cycle heat pump processes solar energy collected at low temperatures (40 to 80 F). The speed of the compressor can be adjusted so that the heat pump capacity matches the load, allowing a seasonal coefficient of performance of about 8 to be attained.

Simulation and energy analysis of distributed electric heating system

NASA Astrophysics Data System (ADS)

Yu, Bo; Han, Shenchao; Yang, Yanchun; Liu, Mingyuan

2018-02-01

Distributed electric heating system assistssolar heating systemby using air-source heat pump. Air-source heat pump as auxiliary heat sourcecan make up the defects of the conventional solar thermal system can provide a 24 - hour high - efficiency work. It has certain practical value and practical significance to reduce emissions and promote building energy efficiency. Using Polysun software the system is simulated and compared with ordinary electric boiler heating system. The simulation results show that upon energy request, 5844.5kW energy is saved and 3135kg carbon - dioxide emissions are reduced and5844.5 kWhfuel and energy consumption is decreased with distributed electric heating system. Theeffect of conserving energy and reducing emissions using distributed electric heating systemis very obvious.

Research status and evaluation system of heat source evaluation method for central heating

NASA Astrophysics Data System (ADS)

Sun, Yutong; Qi, Junfeng; Cao, Yi

2018-02-01

The central heating boiler room is a regional heat source heating center. It is also a kind of the urban environment pollution, it is an important section of building energy efficiency. This article through to the evaluation method of central heating boiler room and overviews of the researches during domestic and overseas, summarized the main influence factors affecting energy consumption of industrial boiler under the condition of stable operation. According to the principle of establishing evaluation index system. We can find that is great significance in energy saving and environmental protection for the content of the evaluation index system of the centralized heating system.

An analysis of the vapor flow and the heat conduction through the liquid-wick and pipe wall in a heat pipe with single or multiple heat sources

NASA Technical Reports Server (NTRS)

Chen, Ming-Ming; Faghri, Amir

1990-01-01

A numerical analysis is presented for the overall performance of heat pipes with single or multiple heat sources. The analysis includes the heat conduction in the wall and liquid-wick regions as well as the compressibility effect of the vapor inside the heat pipe. The two-dimensional elliptic governing equations in conjunction with the thermodynamic equilibrium relation and appropriate boundary conditions are solved numerically. The solutions are in agreement with existing experimental data for the vapor and wall temperatures at both low and high operating temperatures.

A brief compendium of correlations and analytical formulae for the thermal field generated by a heat source embedded in porous and purely-conductive media

NASA Astrophysics Data System (ADS)

Conti, P.; Testi, D.; Grassi, W.

2017-11-01

This work reviews and compares suitable models for the thermal analysis of forced convection over a heat source in a porous medium. The set of available models refers to an infinite medium in which a fluid moves over different three heat source geometries: i.e. the moving infinite line source, the moving finite line source, and the moving infinite cylindrical source. In this perspective, the present work presents a plain and handy compendium of the above-mentioned models for forced external convection in porous media; besides, we propose a dimensionless analysis to figure out the reciprocal deviation among available models, helping the selection of the most suitable one in the specific case of interest. Under specific conditions, the advection term becomes ineffective in terms of heat transfer performances, allowing the use of purely-conductive models. For that reason, available analytical and numerical solutions for purely-conductive media are also reviewed and compared, again, by dimensionless criteria. Therefore, one can choose the simplest solution, with significant benefits in terms of computational effort and interpretation of the results. The main outcomes presented in the paper are: the conditions under which the system can be considered subject to a Darcy flow, the minimal distance beyond which the finite dimension of the heat source does not affect the thermal field, and the critical fluid velocity needed to have a significant contribution of the advection term in the overall heat transfer process.

The numerical simulation of heat transfer during a hybrid laser-MIG welding using equivalent heat source approach

NASA Astrophysics Data System (ADS)

Bendaoud, Issam; Matteï, Simone; Cicala, Eugen; Tomashchuk, Iryna; Andrzejewski, Henri; Sallamand, Pierre; Mathieu, Alexandre; Bouchaud, Fréderic

2014-03-01

The present study is dedicated to the numerical simulation of an industrial case of hybrid laser-MIG welding of high thickness duplex steel UR2507Cu with Y-shaped chamfer geometry. It consists in simulation of heat transfer phenomena using heat equivalent source approach and implementing in finite element software COMSOL Multiphysics. A numerical exploratory designs method is used to identify the heat sources parameters in order to obtain a minimal required difference between the numerical results and the experiment which are the shape of the welded zone and the temperature evolution in different locations. The obtained results were found in good correspondence with experiment, both for melted zone shape and thermal history.

GEO3D - Three-Dimensional Computer Model of a Ground Source Heat Pump System

DOE Data Explorer

James Menart

2013-06-07

This file is the setup file for the computer program GEO3D. GEO3D is a computer program written by Jim Menart to simulate vertical wells in conjunction with a heat pump for ground source heat pump (GSHP) systems. This is a very detailed three-dimensional computer model. This program produces detailed heat transfer and temperature field information for a vertical GSHP system.

Numerical simulation of hydrothermal circulation in the Cascade Range, north-central Oregon

USGS Publications Warehouse

Ingebritsen, S.E.; Paulson, K.M.

1990-01-01

Alternate conceptual models to explain near-surface heat-flow observations in the central Oregon Cascade Range involve (1) an extensive mid-crustal magmatic heat source underlying both the Quaternary arc and adjacent older rocks or (2) a narrower deep heat source which is flanked by a relatively shallow conductive heat-flow anomaly caused by regional ground-water flow (the lateral-flow model). Relative to the mid-crustal heat source model, the lateral-flow model suggests a more limited geothermal resource base, but a better-defined exploration target. We simulated ground-water flow and heat transport through two cross sections trending west from the Cascade range crest in order to explore the implications of the two models. The thermal input for the alternate conceptual models was simulated by varying the width and intensity of a basal heat-flow anomaly and, in some cases, by introducing shallower heat sources beneath the Quaternary arc. Near-surface observations in the Breitenbush Hot Springs area are most readily explained in terms of lateral heat transport by regional ground-water flow; however, the deep thermal structure still cannot be uniquely inferred. The sparser thermal data set from the McKenzie River area can be explained either in terms of deep regional ground-water flow or in terms of a conduction-dominated system, with ground-water flow essentially confined to Quaternary rocks and fault zones.

Idealised modelling of ocean circulation driven by conductive and hydrothermal fluxes at the seabed

NASA Astrophysics Data System (ADS)

Barnes, Jowan M.; Morales Maqueda, Miguel A.; Polton, Jeff A.; Megann, Alex P.

2018-02-01

Geothermal heating is increasingly recognised as an important factor affecting ocean circulation, with modelling studies suggesting that this heat source could lead to first-order changes in the formation rate of Antarctic Bottom Water, as well as a significant warming effect in the abyssal ocean. Where it has been represented in numerical models, however, the geothermal heat flux into the ocean is generally treated as an entirely conductive flux, despite an estimated one third of the global geothermal flux being introduced to the ocean via hydrothermal sources. A modelling study is presented which investigates the sensitivity of the geothermally forced circulation to the way heat is supplied to the abyssal ocean. An analytical two-dimensional model of the circulation is described, which demonstrates the effects of a volume flux through the ocean bed. A simulation using the NEMO numerical general circulation model in an idealised domain is then used to partition a heat flux between conductive and hydrothermal sources and explicitly test the sensitivity of the circulation to the formulation of the abyssal heat flux. Our simulations suggest that representing the hydrothermal flux as a mass exchange indeed changes the heat distribution in the abyssal ocean, increasing the advective heat transport from the abyss by up to 35% compared to conductive heat sources. Consequently, we suggest that the inclusion of hydrothermal fluxes can be an important addition to course-resolution ocean models.

Influence of heat and vibration on the movement of the northern fowl mite (Acari: Macronyssidae).

PubMed

Owen, Jeb P; Mullens, Bradley A

2004-09-01

Heat and vibration are common host-generated cues that ectoparasites use to orient to hosts. Three experiments evaluated effects of heat and vibration on the movement of northern fowl mite, Ornithonyssus sylviarum (Canestrini & Fanzago). Individual arrested mites in an isolation chamber always initiated movement (walking) after substrate vibration (7.8-min walking duration), but only initiated movement 50% of the time (2.8-min walking duration) upon exposure to a 3 degrees C heat fluctuation. Heat fluctuation in combination with vibration extended the period of activity by approximately 50% (11.6-min walking duration) compared with activity initiated by vibration alone. Mites with longer time off-host moved for shorter durations. In a choice test, individual mites consistently moved closer to a 35 degrees C heat source 1 or 6 mm away, but not to a heat source 11 mm away. In a circular arena, mites were able to orient accurately to a 35 degrees C heat source and reached the arena edge almost 4 times faster (11.2 s) than mites without a heat source (41.2 s). These results suggest that northern fowl mite is capable of directed thermo-orientation, as well as modulation of activity depending on the type of sensory information perceived. The adaptive significance of this orientation for a "permanent" ectoparasite is discussed.

A study of Ground Source Heat Pump based on a heat infiltrates coupling model established with FEFLOW

NASA Astrophysics Data System (ADS)

Chen, H.; Hu, C.; Chen, G.; Zhang, Q.

2017-12-01

Geothermal heat is a viable source of energy and its environmental impact in terms of CO2 emissions is significantly lower than conventional fossil fuels. it is vital that engineers acquire a proper understanding about the Ground Source Heat Pump (GSHP). In this study, the model of the borehole exchanger under conduction manners and heat infiltrates coupling manners was established with FEFLOW. The energy efficiency, heat transfer endurance and heat transfer in the unit depth were introduced to quantify the energy efficient and the endurance period. The performance of a the Borehole Exchanger (BHE) in soil with and without groundwater seepage was analyzed of heat transfer process between the soil and the working fluid. Basing on the model, the varied regularity of energy efficiency performance an heat transfer endurance with the conditions including the different configuration of the BHE, the soil properties, thermal load characteristic were discussed. Focus on the heat transfer process in multi-layer soil which one layer exist groundwater flow. And an investigation about thermal dispersivity was also analyzed its influence on heat transfer performance. The final result proves that the model of heat infiltrates coupling model established in this context is reasonable, which can be applied to engineering design.

Numerical study of heating the upper atmosphere by acoustic-gravity waves from a local source on the Earth's surface and influence of this heating on the wave propagation conditions

NASA Astrophysics Data System (ADS)

Karpov, I. V.; Kshevetskii, S. P.

2017-11-01

The propagation of acoustic-gravity waves (AGW) from a source on the Earth's surface to the upper atmosphere is investigated with methods of mathematical modeling. The applied non-linear model of wave propagation in the atmosphere is based on numerical integration of a complete set of two-dimensional hydrodynamic equations. The source on the Earth's surface generates waves with frequencies near to the Brunt-Vaisala frequency. The results of simulation have revealed that some region of heating the atmosphere by propagated upward and dissipated AGWs arises above the source at altitudes nearby of 200 km. The horizontal scale of this heated region is about 1000 km in the case of the source that radiates AGWs during approximately 1 h. The appearing of the heated region has changed the conditions of AGW propagation in the atmosphere. When the heated region in the upper atmosphere has been formed, further a waveguide regime of propagation of waves with the periods shorter the Brunt-Vaisala period is realized. The upper boundary of the wave-guide coincides with the arisen heated region in the upper atmosphere. The considered mechanism of formation of large-scale disturbances in the upper atmosphere may be useful for explanation of connections of processes in the upper and lower atmospheric layers.

Mini-Brayton heat source assembly design study. Volume 1: Space shuttle mission. [feasibility of Brayton isotope power system design

NASA Technical Reports Server (NTRS)

1973-01-01

Conceptual design definitions of a heat source assembly for use in nominal 500 watt electrical (W(e)) 1200 W(e)and 2000 W(e) mini-Brayton isotope power systems are reported. The HSA is an independent package which maintains thermal and nuclear control of an isotope fueled heat source and transfers the thermal energy to a Brayton rotating unit turbine-alternator-compressor power conversion unit.

A Study of an Unmanned Lunar Mission for the Assay of Volatile Gases from the Soil

NASA Astrophysics Data System (ADS)

Wittenberg, L. J.; Sviatoslavsky, I. N.; Kulcinski, G. L.; Mogahed, E. A.

1999-01-01

The success of a manned lunar outpost may require that indigenous resources be utilized in order to reduce the requirements for the periodic resupply from Earth for the human inhabitants. Some indigenous lunar resources do exist. For instance, studies of the lunar regoliths, acquired by the Apollo and Luna missions from several maria, indicate that upon heating in a vacuum, these soils evolve the volatile gases: helium (He), hydrogen (H2), carbon dioxide (CO2), carbon monoxide (CO), nitrogen (N2), and sulfur dioxide (SO2). The He, H, C, and N were originally implanted by solar wind These gases would be valuable to supply life-support systems. For instance, the H2 could be used as a rocket fuel, or alternatively, reacted with the mineral ilmenite (FeTiO3), indigenous to the lunar soil, to yield water (H2O). In an enclosed structure irradiated by solar energy, the H2O, N2, and CO2 could be utilized to grow edible plants for lunar inhabitants. Alternatively, the H2O could be electrolyzed, using photovoltaic cells, yielding breathable O. The inert gas He, would be useful for filling inflatable structures. In addition, the lunar He contains a high abundance of the rare isotopic He-3, which has been identified as a potentially valuable fuel for nuclear-fusion space power systems. In order to determine the economic potential of these lunar volatiles, we need information to assess the in situ quantities of these gases and identify the most abundant sites. In order to acquire such information, a large number of soil samples must be acquired and analyzed because it is not known if these volatile gases in the soil vary widely over the distance of a few meters or several kilometers. In addition, all of the lunar soil samples were analyzed on Earth, after being contaminated by terrestrial air and water. For these reasons, therefore, a mobile, robotic vehicle has been proposed that would be landed-on a lunar maria and assay the volatiles evolved by heating the indigenous lunar regolith. A lunar rover platform with the sample equipment attached has been designed. This science platform was conceptionally designed to fit on a small Marsokhod Rover (75 kg) with a 100-km range. The proposed sampling protocol would be to collect two samples, nearly adjacent. If the results agreed within the experimental deviation, the rover would proceed 0.5 km along the planned route and select two new samples. The progress of the rover and the results of the analyses would be continuously monitored from Earth so that the sampling protocol could be revised as needed. The scientific equipment would accomplish the assay of the regolith samples in the following sequence: (1) retrieve a sample of regolith from the lunar surface by use of a scoop mounted on the platform; (2) reduce the sample to about 1 g of particles <200 pm; (3) weigh the sample; (4) characterize the mineral content (TiO2); (5) heat the sample to 1200C in a vacuum furnace; (6) collect the volatiles; (7) characterize the volatile products; and (8) transmit the data. The components of the scientific package were conceptually designed and are briefly described: (1) The heater unit. A 1 g sample of the surface regolith would be placed in a ferritic steel crucible 0.8 cm OD x 1.57 cm high. This container would be placed in a coiled electrical heater inside an evacuated 1-L container. Heat transfer calculations indicate that the sample would attain 1200C in 14 min with a 25-W heater. For a high-Ti maria regolith sufficient gases are released to create a pressure of 70 Pa at 30C, which is a sufficient sample for the mass spectrometer. (2) Determination of metallic elements. Before the sample is heated, a laser beam delivers 0.45-2.0 Joules per pulse at a wave length of 1 micron to the surface of the sample. The absorption of the laser energy vaporizes some of the minerals in the soils. The vaporized ions are quantitatively determined by the mass spectrometer. (3) Mass spectrometer. This instrument must be utilized to characterize the mineral content of the soil and the volatile gases, essentially from 1 to 72 AMU range. A Fourier Transform Mass Spectrometer (FTMS) may be particularly useful for this analysis, but requires testing. (4) Powersupply. The initial power subsystem assumed the availability of a general purpose heat source, or a Radioisotope Thermoelectric Generator. If the launch of an RTG is forbidden for safety reasons, alternative power supplies would be considered such as solar-electric or beamed microwave sources.

[Study of the effect of heat source separation distance on plasma physical properties in laser-pulsed GMAW hybrid welding based on spectral diagnosis technique].

PubMed

Liao, Wei; Hua, Xue-Ming; Zhang, Wang; Li, Fang

2014-05-01

In the present paper, the authors calculated the plasma's peak electron temperatures under different heat source separation distance in laser- pulse GMAW hybrid welding based on Boltzmann spectrometry. Plasma's peak electron densities under the corresponding conditions were also calculated by using the Stark width of the plasma spectrum. Combined with high-speed photography, the effect of heat source separation distance on electron temperature and electron density was studied. The results show that with the increase in heat source separation distance, the electron temperatures and electron densities of laser plasma did not changed significantly. However, the electron temperatures of are plasma decreased, and the electron densities of are plasma first increased and then decreased.

A Review on Electroactive Polymers for Waste Heat Recovery.

PubMed

Kolasińska, Ewa; Kolasiński, Piotr

2016-06-17

This paper reviews materials for thermoelectric waste heat recovery, and discusses selected industrial and distributed waste heat sources as well as recovery methods that are currently applied. Thermoelectric properties, especially electrical conductivity, thermopower, thermal conductivity and the thermoelectric figures of merit, are considered when evaluating thermoelectric materials for waste heat recovery. Alloys and oxides are briefly discussed as materials suitable for medium- and high-grade sources. Electroactive polymers are presented as a new group of materials for low-grade sources. Polyaniline is a particularly fitting polymer for these purposes. We also discuss types of modifiers and modification methods, and their influence on the thermoelectric performance of this class of polymers.

A simple 2-d thermal model for GMA welds

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matteson, M.A.; Franke, G.L.; Vassilaros, M.G.

1996-12-31

The Rosenthal model of heat distribution from a moving source has been used in many applications to predict the temperature distribution during welding. The equation has performed well in its original form or as modified. The expression has a significant limitation for application to gas metal arc welds (GMAW) that have a papilla extending from the root of the weld bead. The shape of the fusion line between the papilla and the plate surface has a concave shape rather than the expected convex shape. However, at some distance from the fusion line the heat affected zone (HAZ) made visible bymore » etching has the expected convex shape predicted by the Rosenthal expression. This anomaly creates a limitation to the use of the Rosenthal expression for predicting GMAW bead shapes or HAZ temperature histories. Current research at the Naval Surface Warfare Center--Carderock Division (NSWC--CD) to develop a computer based model to predict the microstructure of multi-pass GMAW requires a simple expression to predict the fusion line and temperature history of the HAZ for each weld pass. The solution employed for the NSWC--CD research is a modified Rosenthal expression that has a dual heat source. One heat source is a disk source above the plate surface supplying the majority of the heat. The second heat source is smaller and below the surface of the plate. This second heat source helps simulate the penetration power of many GMAW welds that produces the papilla. The assumptions, strengths and limitations of the model are presented along with some applications.« less

Thaw flow control for liquid heat transport systems

DOEpatents

Kirpich, Aaron S.

1989-01-01

In a liquid metal heat transport system including a source of thaw heat for use in a space reactor power system, the thaw flow throttle or control comprises a fluid passage having forward and reverse flow sections and a partition having a plurality of bleed holes therein to enable fluid flow between the forward and reverse sections. The flow throttle is positioned in the system relatively far from the source of thaw heat.

Improving urban district heating systems and assessing the efficiency of the energy usage therein

NASA Astrophysics Data System (ADS)

Orlov, M. E.; Sharapov, V. I.

2017-11-01

The report describes issues in connection with improving urban district heating systems from combined heat power plants (CHPs), to propose the ways for improving the reliability and the efficiency of the energy usage (often referred to as “energy efficiency”) in such systems. The main direction of such urban district heating systems improvement suggests transition to combined heating systems that include structural elements of both centralized and decentralized systems. Such systems provide the basic part of thermal power via highly efficient methods for extracting thermal power plants turbines steam, while peak loads are covered by decentralized peak thermal power sources to be mounted at consumers’ locations, with the peak sources being also reserve thermal power sources. The methodology was developed for assessing energy efficiency of the combined district heating systems, implemented as a computer software product capable of comparatively calculating saving on reference fuel for the system.

Free convection flow of some fractional nanofluids over a moving vertical plate with uniform heat flux and heat source

NASA Astrophysics Data System (ADS)

Azhar, Waqas Ali; Vieru, Dumitru; Fetecau, Constantin

2017-08-01

Free convection flow of some water based fractional nanofluids over a moving infinite vertical plate with uniform heat flux and heat source is analytically and graphically studied. Exact solutions for dimensionless temperature and velocity fields, Nusselt numbers, and skin friction coefficients are established in integral form in terms of modified Bessel functions of the first kind. These solutions satisfy all imposed initial and boundary conditions and reduce to the similar solutions for ordinary nanofluids when the fractional parameters tend to one. Furthermore, they reduce to the known solutions from the literature when the plate is fixed and the heat source is absent. The influence of fractional parameters on heat transfer and fluid motion is graphically underlined and discussed. The enhancement of heat transfer in such flows is higher for fractional nanofluids in comparison with ordinary nanofluids. Moreover, the use of fractional models allows us to choose the fractional parameters in order to get a very good agreement between experimental and theoretical results.

DUAL HEATED ION SOURCE STRUCTURE HAVING ARC SHIFTING MEANS

DOEpatents

Lawrence, E.O.

1959-04-14

An ion source is presented for calutrons, particularly an electrode arrangement for the ion generator of a calutron ion source. The ion source arc chamber is heated and an exit opening with thermally conductive plates defines the margins of the opening. These plates are electrically insulated from the body of the ion source and are connected to a suitable source of voltage to serve as electrodes for shaping the ion beam egressing from the arc chamber.

Electron cyclotron resonance heating by magnetic filter field in a negative hydrogen ion source.

PubMed

Kim, June Young; Cho, Won-Hwi; Dang, Jeong-Jeung; Chung, Kyoung-Jae; Hwang, Y S

2016-02-01

The influence of magnetic filter field on plasma properties in the heating region has been investigated in a planar-type inductively coupled radio-frequency (RF) H(-) ion source. Besides filtering high energy electrons near the extraction region, the magnetic filter field is clearly observed to increase the electron temperature in the heating region at low pressure discharge. With increasing the operating pressure, enhancement of electron temperature in the heating region is reduced. The possibility of electron cyclotron resonance (ECR) heating in the heating region due to stray magnetic field generated by a filter magnet located at the extraction region is examined. It is found that ECR heating by RF wave field in the discharge region, where the strength of an axial magnetic field is approximately ∼4.8 G, can effectively heat low energy electrons. Depletion of low energy electrons in the electron energy distribution function measured at the heating region supports the occurrence of ECR heating. The present study suggests that addition of axial magnetic field as small as several G by an external electromagnet or permanent magnets can greatly increase the generation of highly ro-vibrationally excited hydrogen molecules in the heating region, thus improving the performance of H(-) ion generation in volume-produced negative hydrogen ion sources.

Glass strengthening and patterning methods

DOEpatents

Harper, David C; Wereszczak, Andrew A; Duty, Chad E

2015-01-27

High intensity plasma-arc heat sources, such as a plasma-arc lamp, are used to irradiate glass, glass ceramics and/or ceramic materials to strengthen the glass. The same high intensity plasma-arc heat source may also be used to form a permanent pattern on the glass surface--the pattern being raised above the glass surface and integral with the glass (formed of the same material) by use of, for example, a screen-printed ink composition having been irradiated by the heat source.

Synfuel production in nuclear reactors

DOEpatents

Henning, C.D.

Apparatus and method for producing synthetic fuels and synthetic fuel components by using a neutron source as the energy source, such as a fusion reactor. Neutron absorbers are disposed inside a reaction pipe and are heated by capturing neutrons from the neutron source. Synthetic fuel feedstock is then placed into contact with the heated neutron absorbers. The feedstock is heated and dissociates into its constituent synfuel components, or alternatively is at least preheated sufficiently to use in a subsequent electrolysis process to produce synthetic fuels and synthetic fuel components.

Altered Intrinsic Pyramidal Neuron Properties and Pathway-Specific Synaptic Dysfunction Underlie Aberrant Hippocampal Network Function in a Mouse Model of Tauopathy

PubMed Central

Booth, Clair A.; Witton, Jonathan; Nowacki, Jakub; Tsaneva-Atanasova, Krasimira; Jones, Matthew W.; Randall, Andrew D.

2016-01-01

The formation and deposition of tau protein aggregates is proposed to contribute to cognitive impairments in dementia by disrupting neuronal function in brain regions, including the hippocampus. We used a battery of in vivo and in vitro electrophysiological recordings in the rTg4510 transgenic mouse model, which overexpresses a mutant form of human tau protein, to investigate the effects of tau pathology on hippocampal neuronal function in area CA1 of 7- to 8-month-old mice, an age point at which rTg4510 animals exhibit advanced tau pathology and progressive neurodegeneration. In vitro recordings revealed shifted theta-frequency resonance properties of CA1 pyramidal neurons, deficits in synaptic transmission at Schaffer collateral synapses, and blunted plasticity and imbalanced inhibition at temporoammonic synapses. These changes were associated with aberrant CA1 network oscillations, pyramidal neuron bursting, and spatial information coding in vivo. Our findings relate tauopathy-associated changes in cellular neurophysiology to altered behavior-dependent network function. SIGNIFICANCE STATEMENT Dementia is characterized by the loss of learning and memory ability. The deposition of tau protein aggregates in the brain is a pathological hallmark of dementia; and the hippocampus, a brain structure known to be critical in processing learning and memory, is one of the first and most heavily affected regions. Our results show that, in area CA1 of hippocampus, a region involved in spatial learning and memory, tau pathology is associated with specific disturbances in synaptic, cellular, and network-level function, culminating in the aberrant encoding of spatial information and spatial memory impairment. These studies identify several novel ways in which hippocampal information processing may be disrupted in dementia, which may provide targets for future therapeutic intervention. PMID:26758828

A Rover Concept for Exploring the Surface of Titan

NASA Astrophysics Data System (ADS)

Balint, T. S.; Shirley, J. H.; Schriener, T. M.

2005-12-01

Titan is one of the premier targets for future in-situ exploration in the outer solar system, as unique "pre-biotic" organic chemical processes may be presently occurring at its surface. A mission to the surface of Titan is not as technically difficult as one to Europa; Titan's atmosphere allows for aerobraking descents, the radiation environment is not a mission-critical factor, and the organic materials we want to sample should be widely distributed (and easily accessible). The recent Titan landing by the Huygens Probe has focused considerable scientific interest on this remarkable body, and future missions to Titan are under consideration. We evaluated a Titan Rover mission concept that would have the capability to survive on Titan's surface for a period of 3 terrestrial years. This long mission lifetime is enabled by employing a radioisotope power system (RPS). To minimize costs and use as much flight heritage as possible, we began by assuming that system masses, dimensions, and instrumentation would be comparable to those of the Mars Surface Lander (MSL). We found that a rover configuration with a 110 W (electric) power system and four 1.5 m diameter inflatable wheels could potentially enable traverse distances up to ~500 km, depending on science and mission requirements, surface environments, and the capability of the autonomous navigation system employed. Direct to Earth communication would simplify the mission by removing the need for a relay orbiter. We will describe our strawman instrument payload and rover subsystems. Trades between the potentially available RPS systems (RTG, Advanced RTG, TPV, SRG, Advanced Stirling and Brayton RPSs) will be outlined. While many possible approaches exist for Titan in-situ exploration, the Titan rover concept presented here could provide a scientifically interesting and programmatically affordable solution.

Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy.

PubMed

Blair, Laura J; Frauen, Haley D; Zhang, Bo; Nordhues, Bryce A; Bijan, Sara; Lin, Yen-Chi; Zamudio, Frank; Hernandez, Lidice D; Sabbagh, Jonathan J; Selenica, Maj-Linda B; Dickey, Chad A

2015-01-31

The blood-brain barrier (BBB) is damaged in tauopathies, including progressive supranuclear palsy (PSP) and Alzheimer's disease (AD), which is thought to contribute to pathogenesis later in the disease course. In AD, BBB dysfunction has been associated with amyloid beta (Aß) pathology, but the role of tau in this process is not well characterized. Since increased BBB permeability is found in tauopathies without Aß pathology, like PSP, we suspected that tau accumulation alone could not only be sufficient, but even more important than Aß for BBB damage. Longitudinal evaluation of brain tissue from the tetracycline-regulatable rTg4510 tau transgenic mouse model showed progressive IgG, T cell and red blood cell infiltration. The Evans blue (EB) dye that is excluded from the brain when the BBB is intact also permeated the brains of rTg4510 mice following peripheral administration, indicative of a bonafide BBB defect, but this was only evident later in life. Thus, despite the marked brain atrophy and inflammation that occurs earlier in this model, BBB integrity is maintained. Interestingly, BBB dysfunction emerged at the same time that perivascular tau emerged around major hippocampal blood vessels. However, when tau expression was suppressed using doxycycline, BBB integrity was preserved, suggesting that the BBB can be stabilized in a tauopathic brain by reducing tau levels. For the first time, these data demonstrate that tau alone can initiate breakdown of the BBB, but the BBB is remarkably resilient, maintaining its integrity in the face of marked brain atrophy, neuroinflammation and toxic tau accumulation. Moreover, the BBB can recover integrity when tau levels are reduced. Thus, late stage interventions targeting tau may slow the vascular contributions to cognitive impairment and dementia that occur in tauopathies.

Altered Intrinsic Pyramidal Neuron Properties and Pathway-Specific Synaptic Dysfunction Underlie Aberrant Hippocampal Network Function in a Mouse Model of Tauopathy.

PubMed

Booth, Clair A; Witton, Jonathan; Nowacki, Jakub; Tsaneva-Atanasova, Krasimira; Jones, Matthew W; Randall, Andrew D; Brown, Jonathan T

2016-01-13

The formation and deposition of tau protein aggregates is proposed to contribute to cognitive impairments in dementia by disrupting neuronal function in brain regions, including the hippocampus. We used a battery of in vivo and in vitro electrophysiological recordings in the rTg4510 transgenic mouse model, which overexpresses a mutant form of human tau protein, to investigate the effects of tau pathology on hippocampal neuronal function in area CA1 of 7- to 8-month-old mice, an age point at which rTg4510 animals exhibit advanced tau pathology and progressive neurodegeneration. In vitro recordings revealed shifted theta-frequency resonance properties of CA1 pyramidal neurons, deficits in synaptic transmission at Schaffer collateral synapses, and blunted plasticity and imbalanced inhibition at temporoammonic synapses. These changes were associated with aberrant CA1 network oscillations, pyramidal neuron bursting, and spatial information coding in vivo. Our findings relate tauopathy-associated changes in cellular neurophysiology to altered behavior-dependent network function. Dementia is characterized by the loss of learning and memory ability. The deposition of tau protein aggregates in the brain is a pathological hallmark of dementia; and the hippocampus, a brain structure known to be critical in processing learning and memory, is one of the first and most heavily affected regions. Our results show that, in area CA1 of hippocampus, a region involved in spatial learning and memory, tau pathology is associated with specific disturbances in synaptic, cellular, and network-level function, culminating in the aberrant encoding of spatial information and spatial memory impairment. These studies identify several novel ways in which hippocampal information processing may be disrupted in dementia, which may provide targets for future therapeutic intervention. Copyright © 2016 Booth, Witton et al.

Sulfuric acid-sulfur heat storage cycle

DOEpatents

Norman, John H.

1983-12-20

A method of storing heat is provided utilizing a chemical cycle which interconverts sulfuric acid and sulfur. The method can be used to levelize the energy obtained from intermittent heat sources, such as solar collectors. Dilute sulfuric acid is concentrated by evaporation of water, and the concentrated sulfuric acid is boiled and decomposed using intense heat from the heat source, forming sulfur dioxide and oxygen. The sulfur dioxide is reacted with water in a disproportionation reaction yielding dilute sulfuric acid, which is recycled, and elemental sulfur. The sulfur has substantial potential chemical energy and represents the storage of a significant portion of the energy obtained from the heat source. The sulfur is burned whenever required to release the stored energy. A particularly advantageous use of the heat storage method is in conjunction with a solar-powered facility which uses the Bunsen reaction in a water-splitting process. The energy storage method is used to levelize the availability of solar energy while some of the sulfur dioxide produced in the heat storage reactions is converted to sulfuric acid in the Bunsen reaction.

Demonstration of a non-contact x-ray source using an inductively heated pyroelectric accelerator

NASA Astrophysics Data System (ADS)

Klopfer, Michael; Satchouk, Vladimir; Cao, Anh; Wolowiec, Thomas; Alivov, Yahya; Molloi, Sabee

2015-04-01

X-ray emission from pyroelectric sources can be produced through non-contact thermal cycling using induction heating. In this study, we demonstrated a proof of concept non-contact x-ray source powered via induction heating. An induction heater operating at 62.5 kHz provided a total of 6.5 W of delivered peak thermal power with 140 V DC of driving voltage. The heat was applied to a ferrous substrate mechanically coupled to a cubic 1 cm3 Lithium Niobate (LiNbO3) pyroelectric crystal maintained in a 3-12 mTorr vacuum. The maximum temperature reached was 175 °C in 86 s of heating. The cooling cycle began immediately after heating and was provided by passive radiative cooling. The total combined cycle time was 250 s. x-ray photons were produced and analyzed in both heating and cooling phases. Maximum photon energies of 59 keV and 55 keV were observed during heating and cooling, respectively. Non-contact devices such as this, may find applications in cancer therapy (brachytherapy), non-destructive testing, medical imaging, and physics education fields.

Fuel change possibilities in small heat source

NASA Astrophysics Data System (ADS)

Durčanský, Peter; Kapjor, Andrej; Jandačka, Jozef

2017-09-01

Rural areas are characterized by a larger number of older family houses with higher fuel consumption for heating. Some areas are not gasified, which means that the fuel base for heating the buildings is very limited. Heating is mainly covered by solid fuels with high emissions and low efficiency. But at the same time, the amount of energy in the form of biowaste can be evaluated and used further. We will explore the possibilities to convert biogas to heat of using a gas burner in a small heat source. However, the heat produced can be used other than for heating or hot water production. The added value for heat generation can be the production of electricity, in the use of heat energy through cogeneration unit with unconventional heat engine. The proposed solution could economically benefit the entire system, because electricity is a noble form of energy and its use is versatile.