Experimental study of the dynamics of a ruby laser pumped by a CW argon-ion laser
NASA Technical Reports Server (NTRS)
Afzal, R. S.; Lin, W. P.; Lawandy, N. M.
1989-01-01
A study of the dynamics of a ruby laser pumped by a CW argon-ion laser is presented. The ruby laser is predominantly stable but has two accessible unstable states. One state exhibits chaotic output, while the other results in regular self-pulsing. The conditions needed for instability are discussed and homodyne spectra and temporal maps of the phase-space attractors are obtained. In addition, a numerical simulation of nonlinear beam propagation in ruby is presented that shows that strong deviations from plane-wave behavior exist, and that transverse effects must be incorporated into theoretical models of the instability.
Schoenewolf, Nicola L; Hafner, Jürg; Dummer, Reinhard; Bogdan Allemann, Inja
2015-04-01
Lentigines solares (LS) on the dorsum of hands are often esthetically disturbing. Q-switched ruby laser treatment is highly effective in the treatment of these lesions. Ablative fractional photothermolysis may be a suitable alternative. We compared the Q-switched ruby laser with ablative CO2 fractional photothermolysis for the treatment of solar lentigines. To evaluate the efficacy and side-effects of 694nm Q-switched ruby laser (Sinon) with the ablative 10,600nm CO2 fractional laser (Quantel Excel O2) in an intra-individual side-to-side comparison in the treatment of LS on the dorsum of hands. Eleven patients were included in the study. The hands of each patient were randomized for treatment with the two laser systems. Three treatment sessions were scheduled at weeks 0, 4 and 8. Evaluations by patients, treating physician and blinded experts were scheduled at weeks 0, 4, 8, 16 and 24. The Q-switched ruby laser was significantly more efficacious than the ablative CO2 fractional laser for removing LS on the dorsum of hands (p = 0.01). In this first study on this topic, the Q-switched ruby laser was superior to the ablative CO2 fractional laser in the treatment of lentigines solares on the dorsum of hands.
Seitz, Anna-Theresa; Grunewald, Sonja; Wagner, Justinus A; Simon, Jan C; Paasch, Uwe
2014-12-01
Q-switched laser treatments are considered the standard method for removing both regular and traumatic tattoos. Recently, the removal of tattoo ink using ablative fractional lasers has been reported. Ablative fractional CO2 laser and q-switched ruby laser treatments were used in a split-face mode to compare the safety and efficacy of the two types of laser in removing a traumatic tattoo caused by the explosion of a firework. A male patient suffering from a traumatic tattoo due to explosive deposits in his entire face was subjected to therapy. A series of eleven treatments were performed. The right side of the face was always treated using an ablative fractional CO2 laser, whereas the left side was treated only using a q-switched ruby laser. After a series of eleven treatments, the patient demonstrated a significant lightening on both sides of his traumatic tattoo, with no clinical difference. After the first six treatments, the patient displayed greater lightening on the right side of his face, whereas after another five treatments, the left side of the patient's face appeared lighter. No side effects were reported. In the initial stage of removing the traumatic tattoo, the ablative fractional laser treatment appeared to be as effective as the standard ruby laser therapy. However, from the 6th treatment onward, the ruby laser therapy was more effective. Although ablative fractional CO2 lasers have the potential to remove traumatic tattoos, they remain a second-line treatment option.
On the creation of the first ruby laser in Moscow
NASA Astrophysics Data System (ADS)
Leontovich, Aleksandr M.; Chizhikova, Zoya A.
2011-01-01
The paper describes the history of the creation of the first ruby laser in 1961 at the Lebedev Physical Institute (FIAN), the USSR Academy of Sciences, Moscow. Appendices present an excerpt of FIAN's 1961 annual report and a talk at the Third International Congress on Quantum Electronics (1963), in which one of the first scientific results obtained with a laser is described.
BLEACHING MECHANISM OF ORGANIC PHOTOTROPIC SUBSTANCES USED IN RUBY LASERS AS SWITCHES,
The bleaching process of organic phototropic switches under the effect of ruby laser emission was examined. The effect of the atomic constants of solutions on the bleaching process is evaluated. (Author)
NASA Astrophysics Data System (ADS)
O'Gorman, T.; Mc Carthy, P. J.; Prunty, S.; Walsh, M. J.; Dunstan, M. R.; Huxford, R. B.; Naylor, G.; Maguet, Emmanuel; Scannell, R.; Shibaev, S.
2010-12-01
A major upgrade to the ruby Thomson scattering (TS) system has been designed and implemented on the Mega-ampere spherical tokamak (MAST). MAST is equipped with two TS systems, a Nd:YAG laser system and a ruby laser system. Apart from common collection optics each system provides independent measurements of the electron temperature and density profile. This paper focuses on the recent upgrades to the ruby TS system. The upgraded ruby TS system measures 512 points across the major radius of the MAST vessel. The ruby laser can deliver one 10 J 40 ns pulse at 1 Hz or two 5 J pulses separated by 100-800 μs. The Thomson scattered light is collected at F/15 over 1.4 m. This system can resolve small (7 mm) structures at 200 points in both the electron temperature and density channels at high optical contrast; ˜50% modulated transfer function. The system is fully automated for each MAST discharge and requires little adjustment. The estimated measurement error for a 7 mm radial point is <4% of T_e and <3% of n_e in the range of 40 eV to 2 keV, for a density of n_e=2 × 10^{19} m ^{-3}. The photon statistics at lower density can be increased by binning in the radial direction as desired. A new intensified CCD camera design allows the ruby TS system to take two snapshots separated with a minimum time of 230 μs. This is exploited to measure two density and temperature profiles or to measure the plasma background light.
Laboratory model for the study and treatment of traumatic tattoos with the Q-switched ruby laser
NASA Astrophysics Data System (ADS)
Silverman, Richard T.; Lach, Elliot
1994-09-01
The outcome of laser tattoo removal is dependent on the type of laser and characteristics of the tattoo. A rabbit model was developed to study the Q-switched ruby laser in the treatment of traumatic tattooing. On the backs of white New Zealand rabbits, three 3 cm patches were dermabraded and dressed with carbon black and antibiotic ointment. After a healing period of eight weeks, pre-treatment biopsies were obtained, and the rabbits were treated with the Q- switched ruby laser at various fluence settings with a pulse width of 34 nsec. At set intervals, further biopsies were obtained and studied with light and electron microscopic analysis, and photodocumentation was performed. Grossly, clearance of the tattooed areas was noted in the laser treated specimens. More effective clearance was observed with higher fluence treatment. No infections occurred, and hair regrowth was noted in all cases, though the rate seemed to be altered by laser treatment.
Polderman, M C; Pavel, S; le Cessie, S; Grevelink, J M; van Leeuwen, R L
2000-03-01
Unwanted hair growth is a common, usually physiologic phenomenon. In this study the efficacy and tolerability of a long-pulsed ruby laser system was compared with needle electrolysis and hot wax on three parts of the body. Thirty volunteers were treated three times on the forearm (n = 10), on the face (n = 10), or in the pubic area (n = 10) with 25 J/cm2 laser, 40 J/cm2 laser, needle electrolysis, and hot wax therapy. The 25 J/cm2 and 40 J/cm2 laser treated sites showed a statistically significant decrease (38% and 49%, respectively) in the number of hairs at the first visit after the last treatment compared to the pretreatment hair counts. No significant decrease was observed in the needle electrolysis and hot wax treated sites. Laser therapy yielded better results on the forearm than on the face or pubic area and was scored as the least painful. The long-pulsed ruby laser is a promising, well-tolerated method of epilation.
Synchronizable Q-switched, mode-locked, and cavity-dumped ruby laser for plasma diagnostics
NASA Astrophysics Data System (ADS)
Houtman, H.; Meyer, J.
1985-06-01
We report on the design and operation of an optimized version of a Q-switched, mode-locked, and cavity-dumped ruby-laser oscillator. The modulator window is much narrower than that assumed in conventional active mode-lock theory, and is shown to yield much shorter pulses than the latter in cases where the number of round trips is restricted. To allow a high-power pulse (≊1 GW) to evolve in the oscillator, and to allow simple synchronization to a (˜100 ns fixed delay) CO2 laser, a limit of 23 round trips was chosen, but similar limits may be imposed by lasers having short-gain duration as in an excimer laser. Details are given on the single spark gap switching element and Pockels cells, with an analysis of their expected switching speeds, in order to establish the effectiveness of the modulator, as compared to conventional sinusoidally driven active mode lockers. Single pulses of 50-70 mJ are reliably cavity-dumped after only 100-ns delay (23 round trips) with pulse length adjustable from 50-100 ps with ±5-ps stability. Relative timing between the main (CO2) and probe (ruby) pulses allows a measurement accuracy of ±50 ps to be attained.
Synchronizable Q-switched, mode-locked, and cavity-dumped ruby laser for plasma diagnostics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Houtman, H.; Meyer, J.
We report on the design and operation of an optimized version of a Q-switched, mode-locked, and cavity-dumped ruby-laser oscillator. The modulator window is much narrower than that assumed in conventional active mode-lock theory, and is shown to yield much shorter pulses than the latter in cases where the number of round trips is restricted. To allow a high-power pulse (roughly-equal1 GW) to evolve in the oscillator, and to allow simple synchronization to a (approx.100 ns fixed delay) CO/sub 2/ laser, a limit of 23 round trips was chosen, but similar limits may be imposed by lasers having short-gain duration asmore » in an excimer laser. Details are given on the single spark gap switching element and Pockels cells, with an analysis of their expected switching speeds, in order to establish the effectiveness of the modulator, as compared to conventional sinusoidally driven active mode lockers. Single pulses of 50--70 mJ are reliably cavity-dumped after only 100-ns delay (23 round trips) with pulse length adjustable from 50--100 ps with +- 5-ps stability. Relative timing between the main (CO/sub 2/) and probe (ruby) pulses allows a measurement accuracy of +- 50 ps to be attained.« less
Researcher Determining a Ruby Laser’s Effect on a Crystal
1965-05-21
National Aeronautics and Space Administration (NASA) Lewis Research Center researcher Americo Forestieri aims a ruby laser beam at a crystal to determine the effects of its radiation. Forestieri was a researcher in the Electric Component Experiment Section of the Space Power System Division. Lewis was in the midst of a long-term effort to develop methods of delivering electrical power to spacecraft using nuclear, solar, or electrochemical technologies. Ruby lasers contain a ruby crystal with mirrors on either side. The laser action is created when a high-intensity lamp shines around the ruby and excites the electrons in the ruby’s chromium atoms. After the excitation, the electrons emit their ruby-red light. The mirrors reflect some of this red light back and forth inside the ruby which causes other excited chromium atoms to produce additional red light. This continues until the light pulse reaches high power levels and consumes all of the energy stored in the crystal. Forestieri used optical absorption and electron paramagnetic resonance techniques to study the extent and manner in which the radiation interacted with the samples. He determined that individual bands were assigned to specific electronic transitions. He also studied the atomic changes in the ruby crystals after irradiation. He found that complex interactions depend on the crystal pretreatment, purity, and irradiation dose.
Treatment of infraorbital dark circles using 694-nm fractional Q-switched ruby laser.
Xu, Tian-Hua; Li, Yuan-Hong; Chen, John Z S; Gao, Xing-Hua; Chen, Hong-Duo
2016-12-01
The objective of this study was to evaluate the efficacy and safety of using a 694-nm fractional Q-switched ruby laser to treat infraorbital dark circles. Thirty women with infraorbital dark circles (predominant color: dark/brown) participated in this open-labeled study. The participants received eight sessions of 694-nm fractional Q-switched ruby laser treatment using a fluence of 3.0-3.5 J/cm 2 , at an interval of 7 days. The melanin deposition in the lesional skin was observed in vivo using reflectance confocal microscopy (RCM). The morphological changes were evaluated using a global evaluation, an overall self-assessment, and a Mexameter. Twenty-eight of the 30 patients showed global improvements that they rated as excellent or good. Twenty-six patients rated their overall satisfaction as excellent or good. The melanin index indicated a substantial decrease from 240.44 (baseline) to 194.56 (P < 0.05). The RCM results showed a dramatic decrease in melanin deposition in the upper dermis. The adverse effects were minimal. The characteristic finding of dark/brown infraorbital dark circles is caused by increased melanin deposition in the upper dermis. The treatment of these infraorbital dark circles using a 694-nm fractional QSR laser is safe and effective.
Schreiver, Ines; Hutzler, Christoph; Laux, Peter; Berlien, Hans-Peter; Luch, Andreas
2015-08-05
Since laser treatment of tattoos is the favored method for the removing of no longer wanted permanent skin paintings, analytical, biokinetics and toxicological data on the fragmentation pattern of commonly used pigments are urgently required for health safety reasons. Applying dynamic headspace-gas chromatography with mass spectrometric detection (DHS-GC/MS) and comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GCxGC-ToF-MS), we identified 1,2-benzene dicarbonitrile, benzonitrile, benzene, and the poisonous gas hydrogen cyanide (HCN) as main fragmentation products emerging dose-dependently upon ruby laser irradiation of the popular blue pigment copper phthalocyanine in suspension. Skin cell viability was found to be significantly compromised at cyanide levels of ≥1 mM liberated during ruby laser irradiation of >1.5 mg/ml phthalocyanine blue. Further, for the first time we introduce pyrolysis-GC/MS as method suitable to simulate pigment fragmentation that may occur spontaneously or during laser removal of organic pigments in the living skin of tattooed people. According to the literature such regular tattoos hold up to 9 mg pigment/cm(2) skin.
Schreiver, Ines; Hutzler, Christoph; Laux, Peter; Berlien, Hans-Peter; Luch, Andreas
2015-01-01
Since laser treatment of tattoos is the favored method for the removing of no longer wanted permanent skin paintings, analytical, biokinetics and toxicological data on the fragmentation pattern of commonly used pigments are urgently required for health safety reasons. Applying dynamic headspace—gas chromatography with mass spectrometric detection (DHS—GC/MS) and comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GCxGC—ToF-MS), we identified 1,2-benzene dicarbonitrile, benzonitrile, benzene, and the poisonous gas hydrogen cyanide (HCN) as main fragmentation products emerging dose-dependently upon ruby laser irradiation of the popular blue pigment copper phthalocyanine in suspension. Skin cell viability was found to be significantly compromised at cyanide levels of ≥1 mM liberated during ruby laser irradiation of >1.5 mg/ml phthalocyanine blue. Further, for the first time we introduce pyrolysis-GC/MS as method suitable to simulate pigment fragmentation that may occur spontaneously or during laser removal of organic pigments in the living skin of tattooed people. According to the literature such regular tattoos hold up to 9 mg pigment/cm2 skin. PMID:26243473
NASA Astrophysics Data System (ADS)
Schreiver, Ines; Hutzler, Christoph; Laux, Peter; Berlien, Hans-Peter; Luch, Andreas
2015-08-01
Since laser treatment of tattoos is the favored method for the removing of no longer wanted permanent skin paintings, analytical, biokinetics and toxicological data on the fragmentation pattern of commonly used pigments are urgently required for health safety reasons. Applying dynamic headspace—gas chromatography with mass spectrometric detection (DHS—GC/MS) and comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GCxGC—ToF-MS), we identified 1,2-benzene dicarbonitrile, benzonitrile, benzene, and the poisonous gas hydrogen cyanide (HCN) as main fragmentation products emerging dose-dependently upon ruby laser irradiation of the popular blue pigment copper phthalocyanine in suspension. Skin cell viability was found to be significantly compromised at cyanide levels of ≥1 mM liberated during ruby laser irradiation of >1.5 mg/ml phthalocyanine blue. Further, for the first time we introduce pyrolysis-GC/MS as method suitable to simulate pigment fragmentation that may occur spontaneously or during laser removal of organic pigments in the living skin of tattooed people. According to the literature such regular tattoos hold up to 9 mg pigment/cm2 skin.
Ohshiro, Takafumi; Sasaki, Katsumi; Takenouchi, Kiyofumi; Kozuma, Mituaki; Ohshiro, Naoyuki; Kageyama, Yuichi
2013-01-01
Background and aims: There are many Q-switched lasers. The Q-switched ruby laser is the one most popularly used in dermatology, aesthetic surgery and plastic surgery, to remove pigmented lesions or tattoos. Correct and regular calibration of such a system is essential. However, some clinics fail to perform this with the excuse of having no measuring instrument (MI) in their offices or treatment rooms in some of their hospitals or clinics, or even the case of well-known medical universities in Japan. The present article explains the precise calibration procedure and beam pattern checking for the Q-switched ruby systems in the first author's clinic. Rationale: In the case of treatment with a medical laser, the calibration and the irradiated pattern (IP) check of the laser being used for treatment are the most important factors for treatment efficacy and safety. If these factors change, the treatment result could be different from that expected. Such kind of data are not acceptable as scientific information for a presentation or published paper. With such unreliable results and incorrect beam pattern, replicating such a study would be impossible Regular calibration check: In our clinic, we have 2 Q-switched ruby laser systems. On a daily basis, the beam patterns, both the optical axis of the beam and its treatment footprint, are checked on dedicated printed sheets and footprint paper, respectively, at the beginning of the day and after the last procedure. Every two weeks we calibrate our systems in-house using a precise MI. Every six months we calibrate the systems in-house with the MI, and then we send the systems back to the manufacturers for calibration. Once every year, we have our MI calibrated by an accredited facility in Japan. In this way, we are not only ensuring accurate and safe treatment for our patients, but we are also producing accurate system and treatment data which can be replicated by others, the basis of evidence-based medicine. PMID:24204090
BioRuby: bioinformatics software for the Ruby programming language.
Goto, Naohisa; Prins, Pjotr; Nakao, Mitsuteru; Bonnal, Raoul; Aerts, Jan; Katayama, Toshiaki
2010-10-15
The BioRuby software toolkit contains a comprehensive set of free development tools and libraries for bioinformatics and molecular biology, written in the Ruby programming language. BioRuby has components for sequence analysis, pathway analysis, protein modelling and phylogenetic analysis; it supports many widely used data formats and provides easy access to databases, external programs and public web services, including BLAST, KEGG, GenBank, MEDLINE and GO. BioRuby comes with a tutorial, documentation and an interactive environment, which can be used in the shell, and in the web browser. BioRuby is free and open source software, made available under the Ruby license. BioRuby runs on all platforms that support Ruby, including Linux, Mac OS X and Windows. And, with JRuby, BioRuby runs on the Java Virtual Machine. The source code is available from http://www.bioruby.org/. katayama@bioruby.org
The Ruby UCSC API: accessing the UCSC genome database using Ruby.
Mishima, Hiroyuki; Aerts, Jan; Katayama, Toshiaki; Bonnal, Raoul J P; Yoshiura, Koh-ichiro
2012-09-21
The University of California, Santa Cruz (UCSC) genome database is among the most used sources of genomic annotation in human and other organisms. The database offers an excellent web-based graphical user interface (the UCSC genome browser) and several means for programmatic queries. A simple application programming interface (API) in a scripting language aimed at the biologist was however not yet available. Here, we present the Ruby UCSC API, a library to access the UCSC genome database using Ruby. The API is designed as a BioRuby plug-in and built on the ActiveRecord 3 framework for the object-relational mapping, making writing SQL statements unnecessary. The current version of the API supports databases of all organisms in the UCSC genome database including human, mammals, vertebrates, deuterostomes, insects, nematodes, and yeast.The API uses the bin index-if available-when querying for genomic intervals. The API also supports genomic sequence queries using locally downloaded *.2bit files that are not stored in the official MySQL database. The API is implemented in pure Ruby and is therefore available in different environments and with different Ruby interpreters (including JRuby). Assisted by the straightforward object-oriented design of Ruby and ActiveRecord, the Ruby UCSC API will facilitate biologists to query the UCSC genome database programmatically. The API is available through the RubyGem system. Source code and documentation are available at https://github.com/misshie/bioruby-ucsc-api/ under the Ruby license. Feedback and help is provided via the website at http://rubyucscapi.userecho.com/.
The Ruby UCSC API: accessing the UCSC genome database using Ruby
2012-01-01
Background The University of California, Santa Cruz (UCSC) genome database is among the most used sources of genomic annotation in human and other organisms. The database offers an excellent web-based graphical user interface (the UCSC genome browser) and several means for programmatic queries. A simple application programming interface (API) in a scripting language aimed at the biologist was however not yet available. Here, we present the Ruby UCSC API, a library to access the UCSC genome database using Ruby. Results The API is designed as a BioRuby plug-in and built on the ActiveRecord 3 framework for the object-relational mapping, making writing SQL statements unnecessary. The current version of the API supports databases of all organisms in the UCSC genome database including human, mammals, vertebrates, deuterostomes, insects, nematodes, and yeast. The API uses the bin index—if available—when querying for genomic intervals. The API also supports genomic sequence queries using locally downloaded *.2bit files that are not stored in the official MySQL database. The API is implemented in pure Ruby and is therefore available in different environments and with different Ruby interpreters (including JRuby). Conclusions Assisted by the straightforward object-oriented design of Ruby and ActiveRecord, the Ruby UCSC API will facilitate biologists to query the UCSC genome database programmatically. The API is available through the RubyGem system. Source code and documentation are available at https://github.com/misshie/bioruby-ucsc-api/ under the Ruby license. Feedback and help is provided via the website at http://rubyucscapi.userecho.com/. PMID:22994508
USDA-ARS?s Scientific Manuscript database
The Agricultural Research Service hereby releases for propagation the new nectarine variety ‘Ruby Splendor,’ tested previously as Y426-227. ‘Ruby Splendor’ was first selected in 2001 among 70 seedlings from the planned hybridization of two unnamed nectarine selections. Fruit of ‘Ruby Splendor’ ripen...
Influence of radiation damage on ruby as a pressure gauge
DOE Office of Scientific and Technical Information (OSTI.GOV)
Schuster, B.; GSI Helmholtzzentrum fuer Schwerionenforschung, Planckstr. 1, 64291 Darmstadt; Weikusat, C.
2010-11-01
This study tackles the question if ruby crystals, irradiated with energetic heavy ions, can still be used as reliable pressure sensors. The problem is linked to novel irradiation experiments, exposing pressurized samples to swift heavy-ion beams. In order to test and quantify a possible influence of radiation damage on the laser-induced fluorescence lines of ruby (Al{sub 2}O{sub 3}:Cr{sup 3+}), small crystals were exposed to different heavy ions (Xe, Au, and U) with kinetic energies of several giga-electron volt at ambient as well as high-pressure conditions. With increasing fluence (ions/cm{sup 2}), the R{sub 1} and R{sub 2} lines shift both tomore » lower wavelengths which leads to an underestimation of the pressure. An empirical correction term {epsilon} is proposed to include the irradiation damage effect into the commonly employed ruby calibration scale.« less
A Low-Cost Time-Resolved Spectrometer for the Study of Ruby Emission
ERIC Educational Resources Information Center
McBane, George C.; Cannella, Christian; Schaertel, Stephanie
2018-01-01
A low-cost time-resolved emission spectrometer optimized for ruby emission is presented. The use of a Class II diode laser module as the excitation source reduces costs and hazards. The design presented here can facilitate the inclusion of time-resolved emission spectroscopy with laser excitation sources in the undergraduate laboratory curriculum.…
Böhnke, Stefanie; Perner, Mirjam
2015-03-01
Ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO) is a key enzyme of the Calvin cycle, which is responsible for most of Earth's primary production. Although research on RubisCO genes and enzymes in plants, cyanobacteria and bacteria has been ongoing for years, still little is understood about its regulation and activation in bacteria. Even more so, hardly any information exists about the function of metagenomic RubisCOs and the role of the enzymes encoded on the flanking DNA owing to the lack of available function-based screens for seeking active RubisCOs from the environment. Here we present the first solely activity-based approach for identifying RubisCO active fosmid clones from a metagenomic library. We constructed a metagenomic library from hydrothermal vent fluids and screened 1056 fosmid clones. Twelve clones exhibited RubisCO activity and the metagenomic fragments resembled genes from Thiomicrospira crunogena. One of these clones was further analyzed. It contained a 35.2 kb metagenomic insert carrying the RubisCO gene cluster and flanking DNA regions. Knockouts of twelve genes and two intergenic regions on this metagenomic fragment demonstrated that the RubisCO activity was significantly impaired and was attributed to deletions in genes encoding putative transcriptional regulators and those believed to be vital for RubisCO activation. Our new technique revealed a novel link between a poorly characterized gene and RubisCO activity. This screen opens the door to directly investigating RubisCO genes and respective enzymes from environmental samples.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Feng Yejun
2011-04-15
Ruby (Al{sub 2}O{sub 3}, with {approx}0.5 wt. % Cr doping) is one of the most widely used manometers at the giga-Pascal scale. Traditionally, its fluorescence is excited with intense laser sources. Here, I present a simple, robust, and portable design that employs light-emitting diodes (LEDs) instead. This LED-based system is safer in comparison with laser-based ones.
Momosawa, Akira; Kurita, Masakazu; Ozaki, Mine; Miyamoto, Shinpei; Kobayashi, Yo; Ban, Izumi; Harii, Kiyonori
2008-01-01
Periorbital skin hyperpigmentation, so-called dark circles, is of major concern for many people. However, only a few reports refer to the morbidity and treatment, and as far as the authors know, there are no reports of the condition in Asians. A total of 18 Japanese patients underwent combined therapy using Q-switched ruby laser to eliminate dermal pigmentation following topical bleaching treatment with tretinoin aqueous gel and hydroquinone ointment performed initially (6 weeks) to reduce epidermal melanin. Both steps were repeated two to four times until physical clearance of the pigmentation was confirmed and patient satisfaction was achieved. Skin biopsy was performed at baseline in each patient and at the end of treatment in three patients, all with informed consent. Clinical and histologic appearances of periorbital hyperpigmentation were evaluated and rated as excellent, good, fair, poor, or default. Seven of 18 patients (38.9 percent) showed excellent clearing after treatment and eight (44.4 percent) were rated good. Only one (5.6 percent) was rated fair and none was rated poor. Postinflammatory hyperpigmentation was observed in only two patients (11.1 percent). Histologic examination showed obvious epidermal hyperpigmentation in 10 specimens. Dermal pigmentation was observed in all specimens but was not considered to be melanocytosis. Remarkable reduction of dermal pigmentation was observed in the biopsy specimens of three patients after treatment. The new treatment protocol combining Q-switched ruby laser and topical bleaching treatment using tretinoin and hydroquinone is considered effective for improvement of periorbital skin hyperpigmentation, with a low incidence of postinflammatory hyperpigmentation.
Falcone, D L; Tabita, F R
1991-01-01
A Rhodobacter sphaeroides ribulose 1,5-bisphosphate carboxylase-oxygenase (RubisCO) deletion strain was constructed that was complemented by plasmids containing either the form I or form II CO2 fixation gene cluster. This strain was also complemented by genes encoding foreign RubisCO enzymes expressed from a Rhodospirillum rubrum RubisCO promoter. In R. sphaeroides, the R. rubrum promoter was regulated, resulting in variable levels of disparate RubisCO molecules under different growth conditions. Photosynthetic growth of the R. sphaeroides deletion strain complemented with cyanobacterial RubisCO revealed physiological properties reflective of the unique cellular environment of the cyanobacterial enzyme. The R. sphaeroides RubisCO deletion strain and R. rubrum promoter system may be used to assess the properties of mutagenized proteins in vivo, as well as provide a potential means to select for altered RubisCO molecules after random mutagenesis of entire genes or gene regions encoding RubisCO enzymes. Images PMID:1900508
Ruby-based inorganic scintillation detectors for 192Ir brachytherapy
NASA Astrophysics Data System (ADS)
Kertzscher, Gustavo; Beddar, Sam
2016-11-01
We tested the potential of ruby inorganic scintillation detectors (ISDs) for use in brachytherapy and investigated various unwanted luminescence properties that may compromise their accuracy. The ISDs were composed of a ruby crystal coupled to a poly(methyl methacrylate) fiber-optic cable and a charge-coupled device camera. The ISD also included a long-pass filter that was sandwiched between the ruby crystal and the fiber-optic cable. The long-pass filter prevented the Cerenkov and fluorescence background light (stem signal) induced in the fiber-optic cable from striking the ruby crystal, which generates unwanted photoluminescence rather than the desired radioluminescence. The relative contributions of the radioluminescence signal and the stem signal were quantified by exposing the ruby detectors to a high-dose-rate brachytherapy source. The photoluminescence signal was quantified by irradiating the fiber-optic cable with the detector volume shielded. Other experiments addressed time-dependent luminescence properties and compared the ISDs to commonly used organic scintillator detectors (BCF-12, BCF-60). When the brachytherapy source dwelled 0.5 cm away from the fiber-optic cable, the unwanted photoluminescence was reduced from >5% to <1% of the total signal as long as the ISD incorporated the long-pass filter. The stem signal was suppressed with a band-pass filter and was <3% as long as the source distance from the scintillator was <7 cm. Some ruby crystals exhibited time-dependent luminescence properties that altered the ruby signal by >5% within 10 s from the onset of irradiation and after the source had retracted. The ruby-based ISDs generated signals of up to 20 times that of BCF-12-based detectors. The study presents solutions to unwanted luminescence properties of ruby-based ISDs for high-dose-rate brachytherapy. An optic filter should be sandwiched between the ruby crystal and the fiber-optic cable to suppress the
Ruby-based inorganic scintillation detectors for 192Ir brachytherapy
Kertzscher, Gustavo; Beddar, Sam
2016-01-01
We tested the potential of ruby inorganic scintillation detectors (ISDs) for use in brachytherapy and investigated various unwanted luminescence properties that may compromise their accuracy. The ISDs were composed of a ruby crystal coupled to a poly(methyl methacrylate) fiber-optic cable and a charge-coupled device camera. The ISD also included a long-pass filter that was sandwiched between the ruby crystal and the fiber-optic cable. The long-pass filter prevented the Cerenkov and fluorescence background light (stem signal) induced in the fiber-optic cable from striking the ruby crystal, which generates unwanted photoluminescence rather than the desired radioluminescence. The relative contributions of the radioluminescence signal and the stem signal were quantified by exposing the ruby detectors to a high-dose-rate brachytherapy source. The photoluminescence signal was quantified by irradiating the fiber-optic cable with the detector volume shielded. Other experiments addressed time-dependent luminescence properties and compared the ISDs to commonly used organic scintillator detectors (BCF-12, BCF-60). When the brachytherapy source dwelled 0.5 cm away from the fiber-optic cable, the unwanted photoluminescence was reduced from > 5% to < 1% of the total signal as long as the ISD incorporated the long-pass filter. The stem signal was suppressed with a band-pass filter and was < 3% as long as the source distance from the scintillator was < 7 cm. Some ruby crystals exhibited time-dependent luminescence properties that altered the ruby signal by > 5% within 10 s from the onset of irradiation and after the source had retracted. The ruby-based ISDs generated signals of up to 20 times that of BCF-12-based detectors. The study presents solutions to unwanted luminescence properties of ruby-based ISDs for high-dose-rate brachytherapy. An optic filter should be sandwiched between the ruby crystal and the fiber-optic cable to suppress the photoluminescence. Furthermore, we
Ruby-based inorganic scintillation detectors for 192Ir brachytherapy.
Kertzscher, Gustavo; Beddar, Sam
2016-11-07
We tested the potential of ruby inorganic scintillation detectors (ISDs) for use in brachytherapy and investigated various unwanted luminescence properties that may compromise their accuracy. The ISDs were composed of a ruby crystal coupled to a poly(methyl methacrylate) fiber-optic cable and a charge-coupled device camera. The ISD also included a long-pass filter that was sandwiched between the ruby crystal and the fiber-optic cable. The long-pass filter prevented the Cerenkov and fluorescence background light (stem signal) induced in the fiber-optic cable from striking the ruby crystal, which generates unwanted photoluminescence rather than the desired radioluminescence. The relative contributions of the radioluminescence signal and the stem signal were quantified by exposing the ruby detectors to a high-dose-rate brachytherapy source. The photoluminescence signal was quantified by irradiating the fiber-optic cable with the detector volume shielded. Other experiments addressed time-dependent luminescence properties and compared the ISDs to commonly used organic scintillator detectors (BCF-12, BCF-60). When the brachytherapy source dwelled 0.5 cm away from the fiber-optic cable, the unwanted photoluminescence was reduced from >5% to <1% of the total signal as long as the ISD incorporated the long-pass filter. The stem signal was suppressed with a band-pass filter and was <3% as long as the source distance from the scintillator was <7 cm. Some ruby crystals exhibited time-dependent luminescence properties that altered the ruby signal by >5% within 10 s from the onset of irradiation and after the source had retracted. The ruby-based ISDs generated signals of up to 20 times that of BCF-12-based detectors. The study presents solutions to unwanted luminescence properties of ruby-based ISDs for high-dose-rate brachytherapy. An optic filter should be sandwiched between the ruby crystal and the fiber-optic cable to suppress the
Ion beam analysis of rubies and their simulants
NASA Astrophysics Data System (ADS)
Juncomma, U.; Intarasiri, S.; Bootkul, D.; Tippawan, U.
2014-07-01
Ion beam analysis (IBA) is a set of well known powerful analytical techniques which use energetic particle beam as a probe. Among them, two techniques are suitable for gemological analysis, i.e., Particle Induced X-rays Emission (PIXE) and Ionoluminescence (IL). We combine these two techniques for the investigations of rubies and their simulants. The main objective is to find a reference fingerprint of these gemstones. The data are collected from several natural rubies, synthetic rubies, red spinels, almandine garnets and rubellite which very much resemble and are difficult to distinguish with the gemologist loupe. From our measurements, due to their different crystal structures and compositions, can be clearly distinguished by the IL and PIXE techniques. The results show that the PIXE spectra consist of a few dominant lines of the host matrix elements of each gemstone and some weaker lines due to trace elements of transition metals. PIXE can easily differentiate rubies from other stones by evaluating their chemical compositions. It is noticed that synthetic rubies generally contain fewer impurities, lower iron and higher chromium than the natural ones. Moreover, the IL spectrum of ruby is unique and different from those of others stones. The typical spectrum of ruby is centered at 694 nm, with small sidebands that can be ascribed to a Cr3+ emission spectrum which is dominated by an R-line at the extreme red end of the visible part of the electromagnetic spectrum. Although the spectrum of synthetic ruby is centered at the same wavelength, the peak is stronger due to higher concentration of Cr and lower concentration of Fe than for natural rubies. For spinel, the IL spectrum shows strong deformation where the R-line is split due to the presence of MgO. For rubellite, the peak center is shifted to 692 nm which might be caused by the replacement of Mn3+ at the Al3+ site of the host structure. It is noticed that almandine garnet is not luminescent due to the
Maria Rubies I Garrofe (1932-1993)
ERIC Educational Resources Information Center
Baste, Carme Amoros
2004-01-01
This article profiles educator Maria Rubies I Garrofe. Rubies was a woman committed to education and the reconstruction of her country, Spain, equipped solely with the force of her convictions and her faith in dialogue. It is difficult to separate her personal commitment from her educational, social and political commitment. From the very outset…
NASA Astrophysics Data System (ADS)
Schmid, F.; Khattak, C. P.
1980-03-01
Conditions for the growth of large, uniformly doped laser crystals by the heat exchanger method are explored. Determination of the melt point, selection of crucible material and establishment of furnace operating parameters are discussed. The melt point of ruby was found to be 2040 plus or minus 10 C. Molybdenum crucibles can be used to contain ruby in vacuum as well as under argon atmospheres at desired superheat temperatures over extended periods required for crystal growth. Thermodynamic analysis was conducted and vapor pressures of volatile species calculated. Experimentally, volatilization of chromium oxides was suppressed by using welded covers on crucibles and operating under an argon pressure in the furnace.
NASA Astrophysics Data System (ADS)
Sutherland, Frederick L.; Graham, Ian T.; Harris, Stephen J.; Coldham, Terry; Powell, William; Belousova, Elena A.; Martin, Laure
2017-05-01
Rare ruby crystals appear among prevailing sapphire crystals mined from placers within basaltic areas in the New England gem-field, New South Wales, Australia. New England ruby (NER) has distinctive trace element features compared to those from ruby elsewhere in Australia and indeed most ruby from across the world. The NER suite includes ruby (up to 3370 ppm Cr), pink sapphire (up to 1520 ppm Cr), white sapphire (up to 910 ppm) and violet, mauve, purple, or bluish sapphire (up to 1410 ppm Cr). Some crystals show outward growth banding in this respective colour sequence. All four colour zones are notably high in Ga (up to 310 ppm) and Si (up to 1820 ppm). High Ga and Ga/Mg values are unusual in ruby and its trace element plots (laser ablation-inductively coupled plasma-mass spectrometry) and suggests that magmatic-metasomatic inputs were involved in the NER suite genesis. In situ oxygen isotope analyses (secondary ion mass spectrometry) across the NER suite colour range showed little variation (n = 22; δ18O = 4.4 ± 0.4, 2σ error), and are values typical for corundum associated with ultramafic/mafic rocks. The isolated NER xenocryst suite, corroded by basalt transport and with few internal inclusions, presents a challenge in deciphering its exact origin. Detailed consideration of its high Ga chemistry in relation to the known geology of the surrounding region was used to narrow down potential sources. These include Late Palaeozoic-Triassic fractionated I-type granitoid magmas or Mesozoic-Cenozoic felsic fractionates from basaltic magmas that interacted with early Palaeozoic Cr-bearing ophiolite bodies in the New England Orogen. Other potential sources may lie deeper within lower crust-mantle metamorphic assemblages, but need to match the anomalous high-Ga geochemistry of the New England ruby suite.
Levin, Melissa Kanchanapoomi; Ng, Elise; Bae, Yoon-Soo Cindy; Brauer, Jeremy A; Geronemus, Roy G
2016-02-01
Laser procedures in skin of color (SOC) patients are challenging due to the increased risk of dyspigmentation and scarring. A novel 755 nm alexandrite picosecond laser has demonstrated effectiveness for tattoo removal and treatment of acne scars. No studies to date have evaluated its applications in pigmentary disorders. The purpose of this retrospective study was to evaluate the safety profile and efficacy of the picosecond alexandrite laser compared to the current standard treatment, Q-switched ruby and neodynium (Nd):YAG nanosecond lasers, for pigmentary disorders in SOC patients. A retrospective photographic and chart evaluation of seventy 755 nm alexandrite picosecond, ninety-two Q-switched frequency doubled 532 nm and 1,064 nm Nd:YAG nanosecond, and forty-seven Q-switched 694 nm ruby nanosecond laser treatments, in forty-two subjects of Fitzpatrick skin types III-VI was conducted in a single laser specialty center. The picosecond laser was a research prototype device. Treatment efficacy was assessed by two blinded physician evaluators, using a visual analog scale for percentage of pigmentary clearance in standard photographs. Subject assessment of efficacy, satisfaction, and adverse events was performed using a questionnaire survey. The most common pigmentary disorder treated was Nevus of Ota (38.1%), followed by solar lentigines (23.8%). Other pigmentary disorders included post-inflammatory hyperpigmentation, congenital nevus, café au lait macule, dermal melanocytosis, Nevus of Ito, and Becker's nevus. Clinical efficacy of the Q-switched nanosecond lasers and picosecond laser treatments were comparable for lesions treated on the face with a mean visual analog score of 2.57 and 2.44, respectively, corresponding to approximately 50% pigmentary clearance. Subject questionnaires were completed in 58.8% of the picosecond subjects and 52.0% of the Q-switched subjects. Eighty four percent of subjects receiving Q-switched nanosecond laser treatments and 50% of the
Njoo, M D; Vodegel, R M; Westerhof, W
2000-05-01
Monobenzylether of hydroquinone is used worldwide to remove residual pigment in patients with vitiligo universalis. Because of the side effects reported with this drug, the use of monobenzylether of hydroquinone has been restricted in The Netherlands. Our purpose was to evaluate the long-term effectiveness and safety of a combination therapy consisting of topical 4-methoxyphenol (4-MP) cream and Q-switched ruby (QSR) laser in 16 patients with vitiligo universalis. In a retrospective study, patient record forms were evaluated. Data were collected regarding history as well as physical and histologic examination. The patients came to the institute for a follow-up visit after a treatment-free period of 2 to 36 months. Thirteen patients received both therapies. Three patients only used the cream. None of the areas was treated by the cream and QSR laser at the same time. In 11 of the 16 patients (69%; 95% confidence interval [CI], 41%-89%) total depigmentation was achieved using the 4-MP cream. Onset of depigmentation was between 4 and 12 months. Four of the 5 patients who did not respond to the 4-MP cream had successful depigmentation with the QSR laser. Mild burning or itching was reported with the cream in 4 cases (25%). Of the 11 patients who responded to the 4-MP cream, 4 had recurrence of pigmentation (relapse rate of 36%; 95% CI, 11%-69%) after a treatment-free period of 2 to 36 months. In 9 of the 13 patients (69%; 95% CI, 39%-91%) total depigmentation was achieved after QSR laser therapy. Onset of depigmentation was between 7 and 14 days after the treatment. Three of the 4 unresponsive patients showed total depigmentation after application of the 4-MP cream. No side effects were observed. Of the 9 patients who responded to QSR laser therapy, 4 had recurrence of pigmentation (relapse rate of 44%; 95% CI, 14%-79%) after a treatment-free period of 2 to 18 months. These patients had a negative Koebner phenomenon. Depigmentation therapy using a 4-MP cream and/or QSR
Marble-hosted ruby deposits of the Morogoro Region, Tanzania
NASA Astrophysics Data System (ADS)
Balmer, Walter A.; Hauzenberger, Christoph A.; Fritz, Harald; Sutthirat, Chakkaphan
2017-10-01
The ruby deposits of the Uluguru and Mahenge Mts, Morogoro Region, are related to marbles which represent the cover sequence of the Eastern Granulites in Tanzania. In both localities the cover sequences define a tectonic unit which is present as a nappe structure thrusted onto the gneissic basement in a north-western direction. Based on structural geological observations the ruby deposits are bound to mica-rich boudins in fold hinges where fluids interacted with the marble-host rock in zones of higher permeability. Petrographic observations revealed that the Uluguru Mts deposits occur within calcite-dominated marbles whereas deposits in the Mahenge Mts are found in dolomite-dominated marbles. The mineral assemblage describing the marble-hosted ruby deposit in the Uluguru Mts is characterised by corundum-dolomite-phlogopite ± spinel, calcite, pargasite, scapolite, plagioclase, margarite, chlorite, tourmaline whereas the assemblage corundum-calcite-plagioclase-phlogopite ± dolomite, pargasite, sapphirine, titanite, tourmaline is present in samples from the Mahenge Mts. Although slightly different in mineral assemblage it was possible to draw a similar ruby formation history for both localities. Two ruby forming events were distinguished by textural differences, which could also be modeled by thermodynamic T-XCO2 calculations using non-ideal mixing models of essential minerals. A first formation of ruby appears to have taken place during the prograde path (M1) either by the breakdown of diaspore which was present in the original sedimentary precursor rock or by the breakdown of margarite to corundum and plagioclase. The conditions for M1 metamorphism was estimated at ∼750 °C at 10 kbar, which represents granulite facies conditions. A change in fluid composition towards a CO2 dominated fluid triggered a second ruby generation to form. Subsequently, the examined units underwent a late greenschist facies overprint. In the framework of the East African Orogen we
Functional metagenomic selection of RubisCOs from uncultivated bacteria
Varaljay, Vanessa A; Satagopan, Sriram; North, Justin A.; Witteveen, Briana; Dourado, Manuella N.; Anantharaman, Karthik; Arbing, Mark A.; McCann, Shelley; Oremland, Ronald S.; Banfield, Jillian F.; Wrighton, Kelly C.; Tabita, F. Robert
2016-01-01
Ribulose 1,5-bisphosphate carboxylase/oxygenase (RubisCO) is a critical yet severely inefficient enzyme that catalyses the fixation of virtually all of the carbon found on Earth. Here, we report a functional metagenomic selection that recovers physiologically active RubisCO molecules directly from uncultivated and largely unknown members of natural microbial communities. Selection is based on CO2-dependent growth in a host strain capable of expressing environmental deoxyribonucleic acid (DNA), precluding the need for pure cultures or screening of recombinant clones for enzymatic activity. Seventeen functional RubisCO-encoded sequences were selected using DNA extracted from soil and river autotrophic enrichments, a photosynthetic biofilm and a subsurface groundwater aquifer. Notably, three related form II RubisCOs were recovered which share high sequence similarity with metagenomic scaffolds from uncultivated members of theGallionellaceae family. One of the Gallionellaceae RubisCOs was purified and shown to possessCO2/O2 specificity typical of form II enzymes. X-ray crystallography determined that this enzyme is a hexamer, only the second form II multimer ever solved and the first RubisCO structure obtained from an uncultivated bacterium. Functional metagenomic selection leverages natural biological diversity and billions of years of evolution inherent in environmental communities, providing a new window into the discovery of CO2-fixing enzymes not previously characterized.
NASA Technical Reports Server (NTRS)
Hochstadt, Jake
2011-01-01
Ruby on Rails is an open source web application framework for the Ruby programming language. The first application I built was a web application to manage and authenticate other applications. One of the main requirements for this application was a single sign-on service. This allowed authentication to be built in one location and be implemented in many different applications. For example, users would be able to login using their existing credentials, and be able to access other NASA applications without authenticating again. The second application I worked on was an internal qualification plan app. Previously, the viewing of employee qualifications was managed through Excel spread sheets. I built a database driven application to streamline the process of managing qualifications. Employees would be able to login securely to view, edit and update their personal qualifications.
Ar-Ar and U-Pb ages of marble-hosted ruby deposits from Central and South-east Asia
NASA Astrophysics Data System (ADS)
Garnier, V.; Giuliani, G.; Maluski, H.; Ohnenstetter, D.; Deloule, E.
2003-04-01
Marble-hosted ruby deposits represent the first source of gemstones in Asia. The deposits from Jegdalek (Afghanistan), Hunza Valley (Pakistan), Nangimali (Azad-Kashmir), Chumar, Ruyil (Nepal), Mogok (Myanmar), Luc Yen, Yen Bai and Quy Chau (Vietnam) were dated using the 40Ar-39Ar laser stepwise heating technique on syngenetic micas. The following ages were obtained : 24.7 ± 0.3 Ma at Jegdalek ; 10.8 ± 0.3 to 5.4 ± 0.3 Ma at Hunza ; 17.2 ± 0.2 to 15.3 ± 0.1 Ma at Nangimali ; 4.6 ± 0.1 Ma at Ruyil ; 5.6 ± 0.4 Ma at Chumar ; 18.7 ± 0.2 to 17.1 ± 0.2 Ma at Mogok ; 33.8 ± 0.4 to 30.8 ± 0.8 Ma at Luc Yen ; 24.4 ± 0.4 to 23.2 ± 0.6 Ma at Yen Bai, 22.1 ± 0.6 to 21.6 ± 0.7 Ma at Quy Chau. These ages represent cooling ages and thus minimum ages for ruby formation. The ages obtained for Nangimali are close to the Ar-Ar cooling age of 19 Ma recorded in the Chichi granite, North to the ruby deposit. However, (C,O)-isotopic studies of the ruby-bearing marbles show no genetic relation between granite emplacement and ruby deposition in this area. The age found at Jegdalek is similar to the K-Ar ages obtained on the Sairobi pegmatitic dykes (20-26 Ma) and of the Jalalabad pluton (25 Ma), located close to the ruby deposit. At Mogok, the ruby deposits yield ages close to those obtained on high grade metamorphic and foliated intrusive regional rocks (15.8 ± 0.7 - 19.5 ± 1.0 Ma). The ages obtained at Chumar and Ruyil agree with those of the Lesser Himalaya Formation (12 - 6 Ma). Those found at Quy Chau agree with those found for the shear zone activity. Furthermore, U-Pb dating was done on zircons included in a ruby from Luc Yen and spinels in marble from Luc Yen and Hunza. The wide range of 238U-206Pb ages obtained for Luc Yen (266 - 45 Ma) evidences a complex metamorphic history. Ruby crystallised at 45 Ma during ductile activity of the Red River shear zone. At Hunza, an 238U-206Pb age of 94.0 ± 2.1 Ma obtained on inherited zircons confirms the U-Pb age obtained on
NASA Astrophysics Data System (ADS)
Zaw, Khin; Sutherland, Lin; Yui, Tzen-Fu; Meffre, Sebastien; Thu, Kyaw
2015-01-01
Rubies and sapphires are of both scientific and commercial interest. These gemstones are corundum colored by transition elements within the alumina crystal lattice: Cr3+ yields red in ruby and Fe2+, Fe3+, and Ti4+ ionic interactions color sapphires. A minor ion, V3+ induces slate to purple colors and color change in some sapphires, but its role in coloring rubies remains enigmatic. Trace element and oxygen isotope composition provide genetic signatures for natural corundum and assist geographic typing. Here, we show that V can dominate chromophore contents in Mogok ruby suites. This raises implications for their color quality, enhancement treatments, geographic origin, exploration and exploitation and their comparison with rubies elsewhere. Precise LA-ICP-MS analysis of ruby and sapphire from Mogok placer and in situ deposits reveal that V can exceed 5,000 ppm, giving V/Cr, V/Fe and V/Ti ratios up to 26, 78, and 97 respectively. Such values significantly exceed those found elsewhere suggesting a localized geological control on V-rich ruby distribution. Our results demonstrate that detailed geochemical studies of ruby suites reveal that V is a potential ruby tracer, encourage comparisons of V/Cr-variation between ruby suites and widen the scope for geographic typing and genesis of ruby. This will allow more precise comparison of Asian and other ruby fields and assist confirmation of Mogok sources for rubies in historical and contemporary gems and jewelry.
RubisCO Gene Clusters Found in a Metagenome Microarray from Acid Mine Drainage
Guo, Xue; Yin, Huaqun; Cong, Jing; Dai, Zhimin; Liang, Yili
2013-01-01
The enzyme responsible for carbon dioxide fixation in the Calvin cycle, ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO), is always detected as a phylogenetic marker to analyze the distribution and activity of autotrophic bacteria. However, such an approach provides no indication as to the significance of genomic content and organization. Horizontal transfers of RubisCO genes occurring in eubacteria and plastids may seriously affect the credibility of this approach. Here, we presented a new method to analyze the diversity and genomic content of RubisCO genes in acid mine drainage (AMD). A metagenome microarray containing 7,776 large-insertion fosmids was constructed to quickly screen genome fragments containing RubisCO form I large-subunit genes (cbbL). Forty-six cbbL-containing fosmids were detected, and six fosmids were fully sequenced. To evaluate the reliability of the metagenome microarray and understand the microbial community in AMD, the diversities of cbbL and the 16S rRNA gene were analyzed. Fosmid sequences revealed that the form I RubisCO gene cluster could be subdivided into form IA and IB RubisCO gene clusters in AMD, because of significant divergences in molecular phylogenetics and conservative genomic organization. Interestingly, the form I RubisCO gene cluster coexisted with the form II RubisCO gene cluster in one fosmid genomic fragment. Phylogenetic analyses revealed that horizontal transfers of RubisCO genes may occur widely in AMD, which makes the evolutionary history of RubisCO difficult to reconcile with organismal phylogeny. PMID:23335778
Trace element fingerprinting of jewellery rubies by external beam PIXE
NASA Astrophysics Data System (ADS)
Calligaro, T.; Poirot, J.-P.; Querré, G.
1999-04-01
External beam PIXE analysis allows the non-destructive in situ characterisation of gemstones mounted on jewellery pieces. This technique was used for the determination of the geographical origin of 64 rubies set on a high-valued necklace. The trace element content of these gemstones was measured and compared to that of a set of rubies of known sources. Multivariate statistical processing of the results allowed us to infer the provenance of rubies : one comes from Thailand/Cambodia deposit while the remaining are attributed to Burma. This highlights the complementary capabilities of PIXE and conventional gemological observations.
Treatment of melasma in Caucasian patients using a novel 694-nm Q-switched ruby fractional laser.
Hilton, Said; Heise, Heike; Buhren, Bettina Alexandra; Schrumpf, Holger; Bölke, Edwin; Gerber, Peter Arne
2013-11-14
Melasma is a common hypermelanosis of the face. The use of a classical Q-switched ruby laser (QSRL) to treat melasma is discussed controversially and is associated with frequent adverse effects, such as hyper- or hypopigmentation. Recently a fractional-mode (FRx) QSRL was developed to minimize the adverse effects of classical QSRL. The objective of this research was to evaluate the efficacy and safety of a novel FRx-QSRL in the treatment of melasma in Caucasian patients. We performed a retrospective study of 25 Caucasian melasma patients (Fitzpatrick skin types I to III). Patients received one to three FRx-QSRL treatments (Tattoostar FRx, Asclepion Laser Technologies, Jena, Germany) at pulse energies of 4 to 8 J/cm2. Three blinded investigators independently evaluated the melasma area and severity index (MASI) score before treatment and at the four- to six-week follow-ups. At additional three-month follow-ups, patients evaluated subjective improvement, pain and over-all satisfaction with the treatment according to a numeric analogue score (NAS). Side effects were documented. At four to six weeks post laser treatment for a mean of 1.4 sessions, we observed a significant (P=0.0001) reduction of the MASI score from 6.54 to 1.98 (72.3%). Patients rated the pain of the intervention at a mean 2.46 points (0=no pain; 10=maximum pain), the improvement at a mean 5.55 points (0=no improvement; 10=maximum improvement) and the overall satisfaction at a mean 4.66 points (0=not satisfied; 10=maximum satisfaction). After three months, post-inflammatory hyperpigmentation (PIH) and/or recurring melasma were observed in 7 (28%) and 11 (44%) patients, respectively. The 694-nm FRx-QSRL is a safe and effective option for treating melasma in Caucasian patients. Over periods of >3 months, PIH and/or recurring melasma may develop at significant rates and may reduce patient satisfaction. Multiple treatment sessions with lower pulse energies and/or a post-interventional therapy with
Satagopan, Sriram; Tabita, F Robert
2016-08-01
Recapturing atmospheric CO2 is key to reducing global warming and increasing biological carbon availability. Ralstonia eutropha is a biotechnologically useful aerobic bacterium that uses the Calvin-Benson-Bassham (CBB) cycle and the enzyme ribulose 1,5-bisphosphate carboxylase/oxygenase (RubisCO) for CO2 utilization, suggesting that it may be a useful host to bioselect RubisCO molecules with improved CO2 -capture capabilities. A host strain of R. eutropha was constructed for this purpose after deleting endogenous genes encoding two related RubisCOs. This strain could be complemented for CO2 -dependent growth by introducing native or heterologous RubisCO genes. Mutagenesis and suppressor selection identified amino acid substitutions in a hydrophobic region that specifically influences RubisCO's interaction with its substrates, particularly O2 , which competes with CO2 at the active site. Unlike most RubisCOs, the R. eutropha enzyme has evolved to retain optimal CO2 -fixation rates in a fast-growing host, despite the presence of high levels of competing O2 . Yet its structure-function properties resemble those of several commonly found RubisCOs, including the higher plant enzymes, allowing strategies to engineer analogous enzymes. Because R. eutropha can be cultured rapidly under harsh environmental conditions (e.g., with toxic industrial flue gas), in the presence of near saturation levels of oxygen, artificial selection and directed evolution studies in this organism could potentially impact efforts toward improving RubisCO-dependent biological CO2 utilization in aerobic environments. d-ribulose 1,5-bisphosphate carboxylase/oxygenase, EC 4.1.1.39; phosphoribulokinase, EC 2.7.1.19. © 2016 Federation of European Biochemical Societies.
mRuby, a Bright Monomeric Red Fluorescent Protein for Labeling of Subcellular Structures
Kredel, Simone; Oswald, Franz; Nienhaus, Karin; Deuschle, Karen; Röcker, Carlheinz; Wolff, Michael; Heilker, Ralf; Nienhaus, G. Ulrich; Wiedenmann, Jörg
2009-01-01
A monomeric variant of the red fluorescent protein eqFP611, mRuby, is described. With excitation and emission maxima at 558 nm and 605 nm, respectively, and a large Stokes shift of 47 nm, mRuby appears particularly useful for imaging applications. The protein shows an exceptional resistance to denaturation at pH extremes. Moreover, mRuby is about ten-fold brighter compared to EGFP when being targeted to the endoplasmic reticulum. The engineering process of eqFP611 revealed that the C-terminal tail of the protein acts as a natural peroxisomal targeting signal (PTS). Using an mRuby variant carrying the eqFP611-PTS, we discovered that ordered inheritance of peroxisomes is widespread during mitosis of different mammalian cell types. The ordered partitioning is realized by the formation of peroxisome clusters around the poles of the mitotic spindle and ensures that equal numbers of the organelle are inherited by the daughter cells. The unique spectral properties make mRuby the marker of choice for a multitude of cell biological applications. Moreover, the use of mRuby has allowed novel insights in the biology of organelles responsible for severe human diseases. PMID:19194514
Wrighton, Kelly C; Castelle, Cindy J; Varaljay, Vanessa A; Satagopan, Sriram; Brown, Christopher T; Wilkins, Michael J; Thomas, Brian C; Sharon, Itai; Williams, Kenneth H; Tabita, F Robert; Banfield, Jillian F
2016-01-01
Metagenomic studies recently uncovered form II/III RubisCO genes, originally thought to only occur in archaea, from uncultivated bacteria of the candidate phyla radiation (CPR). There are no isolated CPR bacteria and these organisms are predicted to have limited metabolic capacities. Here we expand the known diversity of RubisCO from CPR lineages. We report a form of RubisCO, distantly similar to the archaeal form III RubisCO, in some CPR bacteria from the Parcubacteria (OD1), WS6 and Microgenomates (OP11) phyla. In addition, we significantly expand the Peregrinibacteria (PER) II/III RubisCO diversity and report the first II/III RubisCO sequences from the Microgenomates and WS6 phyla. To provide a metabolic context for these RubisCOs, we reconstructed near-complete (>93%) PER genomes and the first closed genome for a WS6 bacterium, for which we propose the phylum name Dojkabacteria. Genomic and bioinformatic analyses suggest that the CPR RubisCOs function in a nucleoside pathway similar to that proposed in Archaea. Detection of form II/III RubisCO and nucleoside metabolism gene transcripts from a PER supports the operation of this pathway in situ. We demonstrate that the PER form II/III RubisCO is catalytically active, fixing CO2 to physiologically complement phototrophic growth in a bacterial photoautotrophic RubisCO deletion strain. We propose that the identification of these RubisCOs across a radiation of obligately fermentative, small-celled organisms hints at a widespread, simple metabolic platform in which ribose may be a prominent currency. PMID:27137126
Wrighton, Kelly C.; Castelle, Cindy J.; Varaljay, Vanessa A.; ...
2016-05-03
Metagenomic studies recently uncovered form II/III RubisCO genes, originally thought to only occur in archaea, from uncultivated bacteria of the candidate phyla radiation (CPR). There are no isolated CPR bacteria and these organisms are predicted to have limited metabolic capacities. Here we expand the known diversity of RubisCO from CPR lineages. We report a form of RubisCO, distantly similar to the archaeal form III RubisCO, in some CPR bacteria from the Parcubacteria (OD1), WS6 and Microgenomates (OP11) phyla. In addition, we significantly expand the Peregrinibacteria (PER) II/III RubisCO diversity and report the first II/III RubisCO sequences from the Microgenomates andmore » WS6 phyla. To provide a metabolic context for these RubisCOs, we reconstructed near-complete ( > 93%) PER genomes and the first closed genome for a WS6 bacterium, for which we propose the phylum name Dojkabacteria. Genomic and bioinformatic analyses suggest that the CPR RubisCOs function in a nucleoside pathway similar to that proposed in Archaea. Detection of form II/III RubisCO and nucleoside metabolism gene transcripts from a PER supports the operation of this pathway in situ. We demonstrate that the PER form II/III RubisCO is catalytically active, fixing CO 2 to physiologically complement phototrophic growth in a bacterial photoautotrophic RubisCO deletion strain. We propose that the identification of these RubisCOs across a radiation of obligately fermentative, small-celled organisms hints at a widespread, simple metabolic platform in which ribose may be a prominent currency.« less
Precision laser range finder system design for Advanced Technology Laboratory applications
NASA Technical Reports Server (NTRS)
Golden, K. E.; Kohn, R. L.; Seib, D. H.
1974-01-01
Preliminary system design of a pulsed precision ruby laser rangefinder system is presented which has a potential range resolution of 0.4 cm when atmospheric effects are negligible. The system being proposed for flight testing on the advanced technology laboratory (ATL) consists of a modelocked ruby laser transmitter, course and vernier rangefinder receivers, optical beacon retroreflector tracking system, and a network of ATL tracking retroreflectors. Performance calculations indicate that spacecraft to ground ranging accuracies of 1 to 2 cm are possible.
An introduction to scripting in Ruby for biologists.
Aerts, Jan; Law, Andy
2009-07-16
The Ruby programming language has a lot to offer to any scientist with electronic data to process. Not only is the initial learning curve very shallow, but its reflection and meta-programming capabilities allow for the rapid creation of relatively complex applications while still keeping the code short and readable. This paper provides a gentle introduction to this scripting language for researchers without formal informatics training such as many wet-lab scientists. We hope this will provide such researchers an idea of how powerful a tool Ruby can be for their data management tasks and encourage them to learn more about it.
Treatment of melasma in Caucasian patients using a novel 694-nm Q-switched ruby fractional laser
2013-01-01
Background Melasma is a common hypermelanosis of the face. The use of a classical Q-switched ruby laser (QSRL) to treat melasma is discussed controversially and is associated with frequent adverse effects, such as hyper- or hypopigmentation. Recently a fractional-mode (FRx) QSRL was developed to minimize the adverse effects of classical QSRL. The objective of this research was to evaluate the efficacy and safety of a novel FRx-QSRL in the treatment of melasma in Caucasian patients. Methods We performed a retrospective study of 25 Caucasian melasma patients (Fitzpatrick skin types I to III). Patients received one to three FRx-QSRL treatments (Tattoostar FRx, Asclepion Laser Technologies, Jena, Germany) at pulse energies of 4 to 8 J/cm2. Three blinded investigators independently evaluated the melasma area and severity index (MASI) score before treatment and at the four- to six-week follow-ups. At additional three-month follow-ups, patients evaluated subjective improvement, pain and over-all satisfaction with the treatment according to a numeric analogue score (NAS). Side effects were documented. Results At four to six weeks post laser treatment for a mean of 1.4 sessions, we observed a significant (P = 0.0001) reduction of the MASI score from 6.54 to 1.98 (72.3%). Patients rated the pain of the intervention at a mean 2.46 points (0 = no pain; 10 = maximum pain), the improvement at a mean 5.55 points (0 = no improvement; 10 = maximum improvement) and the overall satisfaction at a mean 4.66 points (0 = not satisfied; 10 = maximum satisfaction). After three months, post-inflammatory hyperpigmentation (PIH) and/or recurring melasma were observed in 7 (28%) and 11 (44%) patients, respectively. Conclusion The 694-nm FRx-QSRL is a safe and effective option for treating melasma in Caucasian patients. Over periods of >3 months, PIH and/or recurring melasma may develop at significant rates and may reduce patient satisfaction. Multiple treatment
A Ruby API to query the Ensembl database for genomic features.
Strozzi, Francesco; Aerts, Jan
2011-04-01
The Ensembl database makes genomic features available via its Genome Browser. It is also possible to access the underlying data through a Perl API for advanced querying. We have developed a full-featured Ruby API to the Ensembl databases, providing the same functionality as the Perl interface with additional features. A single Ruby API is used to access different releases of the Ensembl databases and is also able to query multi-species databases. Most functionality of the API is provided using the ActiveRecord pattern. The library depends on introspection to make it release independent. The API is available through the Rubygem system and can be installed with the command gem install ruby-ensembl-api.
An introduction to scripting in Ruby for biologists
Aerts, Jan; Law, Andy
2009-01-01
The Ruby programming language has a lot to offer to any scientist with electronic data to process. Not only is the initial learning curve very shallow, but its reflection and meta-programming capabilities allow for the rapid creation of relatively complex applications while still keeping the code short and readable. This paper provides a gentle introduction to this scripting language for researchers without formal informatics training such as many wet-lab scientists. We hope this will provide such researchers an idea of how powerful a tool Ruby can be for their data management tasks and encourage them to learn more about it. PMID:19607723
Rapid middle Miocene extension and unroofing of the southern Ruby Mountains, Nevada
Colgan, Joseph P.; Howard, Keith A.; Fleck, Robert J.; Wooden, Joseph L.
2010-01-01
Paleozoic rocks in the northern Ruby Mountains were metamorphosed during Mesozoic crustal shortening and Cenozoic magmatism, but equivalent strata in the southern Ruby Mountains were never buried deeper than stratigraphic depths prior to exhumation in the footwall of a west dipping brittle normal fault. In the southern Ruby Mountains, Miocene sedimentary rocks in the hanging wall of this fault date from 15.2 to 11.6 Ma and contain abundant detritus from the Paleozoic section. Apatite fission track and (U-Th)/He samples of the Eocene Harrison Pass pluton record rapid cooling that peaked ca. 17–15 Ma, while apatite fission track data from Jurassic plutons east and west of the southern Ruby Mountains indicate near-surface temperatures (<60°C) since the Cretaceous. We interpret these data to record rapid unroofing of the southern Ruby Mountains during slip on the west dipping brittle detachment between 17–16 and 10–12 Ma, followed by minor high-angle faulting. We interpret published Oligocene to early Miocene K-Ar biotite and zircon fission track dates from the Harrison Pass pluton to be partially reset rather than to directly record fault slip. Our new data, together with published data on the distribution and composition of Miocene basin fill, suggest that rapid middle Miocene slip took place on the west dipping brittle detachment that bounds the Ruby Mountains and East Humboldt Range for 150 km along strike. This fault was thus active during a period of rapid extension (ca. 17–15 to 12–10 Ma) documented widely across the northern Basin and Range Province.
Fluorescent cooling of objects exposed to sunlight – The ruby example
DOE Office of Scientific and Technical Information (OSTI.GOV)
Berdahl, Paul; Chen, Sharon S.; Destaillats, Hugo
Various pigments are used to formulate desirable non-white colors that stay cooler in the sun than alternatives, which is particularly useful for hot climate areas. These cool pigments provide a high near-infrared (NIR) reflectance in the solar infrared range of 700-2500 nm, and also a color specified by a reflectance spectrum in the 400-700 nm visible range. Still cooler materials can be formulated by also utilizing the phenomenon of fluorescence (photoluminescence). Ruby, Al 2O 3 :Cr, is a prime example, with efficient emission in the deep red (~694 nm) and near infrared (700-800 nm). A layer of synthetic ruby crystalsmore » on a white surface having an attractive red color can remain cooler in the sun than conventional red materials. Ruby particles can also be used as a red/pink pigment. Increasing the Cr:Al ratio produces a stronger (darker) pigment but doping above ~3 wt% Cr 2O 3 causes concentration quenching of the fluorescence. The system quantum efficiency for lightly doped ruby-pigmented coatings over white is high, 0.83 ± 0.10.« less
A short history of RubisCO: the rise and fall (?) of Nature's predominant CO2 fixing enzyme.
Erb, Tobias J; Zarzycki, Jan
2018-02-01
Ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO) is arguably one of the most abundant proteins in the biosphere and a key enzyme in the global carbon cycle. Although RubisCO has been intensively studied, its evolutionary origins and rise as Nature's most dominant carbon dioxide (CO 2 )-fixing enzyme still remain in the dark. In this review we will bring together biochemical, structural, physiological, microbiological, as well as phylogenetic data to speculate on the evolutionary roots of the CO 2 -fixation reaction of RubisCO, the emergence of RubisCO-based autotrophic CO 2 -fixation in the context of the Calvin-Benson-Bassham cycle, and the further evolution of RubisCO into the 'RubisCOsome', a complex of various proteins assembling and interacting with the enzyme to improve its operational capacity (functionality) under different biological and environmental conditions. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.
Laser surgery and medicine including photodynamic therapy in China today
NASA Astrophysics Data System (ADS)
Li, Junheng
2000-10-01
The development of laser medicine in China is correlated with the development of laser science in China. After the first Chinese laser, ruby laser came into being in 1961, Chinese medical scientists began to do the studies about laser medicine in the middle 1960s. For example, ruby laser was adopted for the retina coagulation experiment in 1965. Since 1970s, through the free choice of utilizing Co2, He-Ne, Nd:YAG argon, ruby lasers, laser surgery and medicine has been widely applied to the treatment for diseases of the eyes, ENT, dermatology, surgery, gynecology, tumors and diseases suitable to physical therapy or acupuncture with satisfactory effects. In June 1977, a nation-wide laser medicine symposium was held at Wuhan, Hubei Province with 200 participants including medical doctors and laser technologies from 23 provinces and municipal towns. Till the end of seventies, utilization of lasers has been extended to Nd glass laser, N laser and tunable dye lasers. The scope covered most of the clinical sections. After Dr. Thomas J. Dougherty developed the PDT for cancers in Roswell Park Memorial Institute in Buffalo in late 1970s and Professor Yoshihiro Hayata successfully applied the PDT in clinical treatment for lung cancer in 1980, Chinese pharmacists successfully produced the Chinese HpD and the first case of PDT, a lower eyelid basal cell carcinoma patient was treated with the Chinese laser equipment in 1981 in Beijing. Its success brought attention establishing a research group supported by the government in 1982. The members of the group consisted the experts on preclinical and clinical research, pharmaceutical chemistry, laser physicists and technologists. A systemic research on PDT was then carried out and obvious result was achieved. The step taken for PDT also accelerated the researchers on other kinds of laser medicine and surgery because the medical doctors had begun to master the knowledge about laser science. The prosperous situation of rapid
Laser reflector with an interference coating
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vol'pyan, O D; Semenov, A A; Yakovlev, P P
1998-10-31
An analysis was made of the reflectivity of interference coatings intended for the use in optical pumping of solid-state lasers. Ruby and Nd{sup 3+}:YAG lasers were used as models in comparative pumping efficiency measurements, carried out employing reflectors with interference and silver coatings. Estimates of the service life of reflectors with interference coatings were obtained. The power of a thermo-optical lens was reduced by the use of such coatings in cw lasers. (laser system components)
Laser Tattoo Removal: A Clinical Update
Ho, Stephanie GY; Goh, Chee Leok
2015-01-01
Techniques for tattoo removal have evolved significantly over the years. The commonly used Quality-switched (QS) ruby, alexandrite, and Nd:YAG lasers are the traditional workhorses for tattoo removal. Newer strategies using combination laser treatments, multi-pass treatments, and picosecond lasers offer promising results. The tattoo color and skin type of the patient are important considerations when choosing the appropriate laser. Standard protocols can be developed for the effective and safe treatment of tattoos. PMID:25949017
Alfreider, Albin; Schirmer, Mario; Vogt, Carsten
2012-03-01
Groundwater polluted with methyl-tert-butyl ether (MTBE) and ammonium was investigated for chemolithoautotrophic CO(2) fixation capabilities based on detailed analyses of ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO) large subunit genes. Samples retrieved from a groundwater conditioning unit, characterized by different redox conditions, were examined for the presence of form IA, form IC (cbbL) and form II (cbbM) RubisCO genes and transcripts obtained from DNA- and RNA-extracts. Form IA RubisCO sequences, which revealed a complex and distinct variety in different sampling stations, were expressed in the original groundwater and in samples amended with oxygen, but not in the aquifer groundwater enriched with nitrate. Form IC RubisCO genes were exclusively detected in groundwater supplied with oxygen and sequences were affiliated with cbbL genes in nitrifying bacteria. cbbM genes were not expressed in the oxygen-amended groundwater, probably due to the low CO(2) /O(2) substrate specificity of this enzyme. Most form II RubisCO transcripts were affiliated with RubisCO genes of denitrifiers, which are important residents in the groundwater supplied with nitrate. The distinct distribution pattern and diversity of RubisCO genes and transcripts obtained in this study suggest that the induction of different RubisCO enzymes is highly regulated and closely linked to the actual environmental conditions. © 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.
Elavarasu, Sugumari; Naveen, Devisree; Thangavelu, Arthiie
2012-08-01
Laser is one of the most captivating technologies in dental practice since Theodore Maiman in 1960 invented the ruby laser. Lasers in dentistry have revolutionized several areas of treatment in the last three and a half decades of the 20(th) century. Introduced as an alternative to mechanical cutting device, laser has now become an instrument of choice in many dental applications. Evidence suggests its use in initial periodontal therapy, surgery, and more recently, its utility in salvaging implant opens up a wide range of applications. More research with better designs are a necessity before lasers can become a part of dental armamentarium. This paper gives an insight to laser in periodontics.
Elavarasu, Sugumari; Naveen, Devisree; Thangavelu, Arthiie
2012-01-01
Laser is one of the most captivating technologies in dental practice since Theodore Maiman in 1960 invented the ruby laser. Lasers in dentistry have revolutionized several areas of treatment in the last three and a half decades of the 20th century. Introduced as an alternative to mechanical cutting device, laser has now become an instrument of choice in many dental applications. Evidence suggests its use in initial periodontal therapy, surgery, and more recently, its utility in salvaging implant opens up a wide range of applications. More research with better designs are a necessity before lasers can become a part of dental armamentarium. This paper gives an insight to laser in periodontics. PMID:23066266
Spin-lattice relaxation and the calculation of gain, pump power, and noise temperature in ruby
NASA Technical Reports Server (NTRS)
Lyons, J. R.
1989-01-01
The use of a quantitative analysis of the dominant source of relaxation in ruby spin systems to make predictions of key maser amplifier parameters is described. The spin-lattice Hamiltonian which describes the interaction of the electron spins with the thermal vibrations of the surrounding lattice is obtained from the literature. Taking into account the vibrational anisotropy of ruby, Fermi's rule is used to calculate the spin transition rates between the maser energy levels. The spin population rate equations are solved for the spin transition relaxation times, and a comparison with previous calculations is made. Predictions of ruby gain, inversion ratio, and noise temperature as a function of physical temperature are made for 8.4-GHz and 32-GHz maser pumping schemes. The theory predicts that ruby oriented at 90 deg will have approximately 50 percent higher gain in dB and slightly lower noise temperature than a 54.7-deg ruby at 32 GHz (assuming pump saturation). A specific calculation relating pump power to inversion ratio is given for a single channel of the 32-GHz reflected wave maser.
Aesthetic value improvement of the ruby stone using heat treatment and its synergetic surface study
NASA Astrophysics Data System (ADS)
Sahoo, Rakesh K.; Mohapatra, Birendra K.; Singh, Saroj K.; Mishra, Barada K.
2015-02-01
The surface behavior of the natural ruby stones before and after heat treatment with metal oxide additives like: zinc oxide (ZnO) and lead oxide (PbO) have been studied. The surface appearance of the ruby stones processed with the metal oxides changed whereas the bulk densities of the stones remained within the range of 3.9-4.0 g/cm3. The cracks healing and pores filling by the metal oxides on the surface of the ruby have been examined using scanning electron microscopy. The chemical compositions based on the XPS survey scans are in good agreement with the expected composition. The phase and crystallinity of the ruby stones original and heat-treated were obtained from their X-ray diffraction patterns. The change in peak separation between R1 and R2 - peaks in photoluminescence spectra and the contrary binding energy shift of the Al 2p peaks in the X-ray photoelectron spectra have been explicated. Moreover, in this work we describe the change in surface chemical and physical characteristics of the ruby stone before and after heat treatment.
Application of laser in obstetrics and gynecology
NASA Astrophysics Data System (ADS)
Ding, Ai-Hua
1998-11-01
Mainman developed the first ruby laser in 1960 and after 13 Kaplan successfully reported the use of CO2 laser in the treatment of cervicitis. Soon after, Chinese gynecologists started to use the laser for diagnosis and therapy. It had been proved that more than 30 kinds of gynecological diseases could be treated effectively by laser. The remarkable laser treatment technique partially replaced with conventional methods used in that century. However, the application of laser had shown a broad prospect along with its further investigation.
Mr.CAS-A minimalistic (pure) Ruby CAS for fast prototyping and code generation
NASA Astrophysics Data System (ADS)
Ragni, Matteo
There are Computer Algebra System (CAS) systems on the market with complete solutions for manipulation of analytical models. But exporting a model that implements specific algorithms on specific platforms, for target languages or for particular numerical library, is often a rigid procedure that requires manual post-processing. This work presents a Ruby library that exposes core CAS capabilities, i.e. simplification, substitution, evaluation, etc. The library aims at programmers that need to rapidly prototype and generate numerical code for different target languages, while keeping separated mathematical expression from the code generation rules, where best practices for numerical conditioning are implemented. The library is written in pure Ruby language and is compatible with most Ruby interpreters.
Zeeman Effect in Ruby at High Pressures
NASA Astrophysics Data System (ADS)
Dan, Ioana
2012-02-01
We have developed a versatile fiber-coupled system for magneto-optical spectroscopy measurements at high pressure. The system is based on a miniature Cu-alloy Diamond Anvil Cell (from D'Anvils, Ltd) fitted with a custom-designed He gas-actuated membrane for in-situ pressure control, and coupled with a He transfer cryostat incorporating a superconducting magnet (from Quantum Designs). This system allows optical measurements (Raman, photoluminescence, reflectivity) within wide ranges of pressures (up to 100GPa), temperatures (4.2-300K) and magnetic fields (0-9T). We employ this system to examine the effect of pressure and non-hydrostatic stress on the Zeeman split d-d transitions of Cr^3+ in ruby (Al2O3: Cr^3+). We determine the effect of pressure and non-hydrostaticity on the trigonal crystal field in this material, and discuss the use of the Zeman-split ruby fluorescence as a possible probe for deviatoric stresses in diamond anvil cell experiments.
Origin of the different color of ruby and emerald
NASA Astrophysics Data System (ADS)
García-Lastra, J. M.; Barriuso, M. T.; Aramburu, J. A.; Moreno, M.
2005-09-01
The different color exhibited by ruby and emerald is a fundamental but still unsolved question. According to recent EXAFS measurements, such a difference can hardly be explained on the basis of a different average distance between Cr3+ and the six oxygen ligands. The puzzling difference in color between the two gemstones is shown in this work to arise essentially from the distinct electrostatic potential imposed by the rest of lattice ions upon the active electrons of the CrO69- unit. Main effects are shown to come from the electric field generated in the neighborhood of the Cr3+ site in ruby which is absent in the case of emerald due to symmetry.
Experimental investigation of self-induced transparency and pulse delay in ruby.
NASA Technical Reports Server (NTRS)
Asher, I. M.
1972-01-01
We have investigated the self-induced transparency effect in ruby over a range of input energies which range from linear absorption to full transparency. The transmission, pulse delay, and pulse broadening were studied as a function of input energy. The transition region is narrower than that found in similar studies of the CO2/SF6 system; this is consistent with predictions based on ensembles of two-level systems. Included are the first pulse-delay and pulse-broadening curves to be obtained for the ruby system.
SPECTRAL AND MODE PROPERTIES OF SOLID-STATE LASERS AND OPTICAL DYNAMIC EFFECTS.
LASERS , OPTICAL PROPERTIES), THERMAL PROPERTIES, FREQUENCY, RUBY, KERR CELLS, ELECTROMAGNETIC PULSES, PHASE LOCKED SYSTEMS, GARNET, NEODYMIUM, CAVITY RESONATORS, INTERFEROMETERS, LIGHT PULSES, PROPAGATION
Performance evaluation of the Abbott CELL-DYN Ruby and the Sysmex XT-2000i haematology analysers.
Leers, M P G; Goertz, H; Feller, A; Hoffmann, J J M L
2011-02-01
Two mid-range haematology analysers (Abbott CELL-DYN Ruby and Sysmex XT-2000i) were evaluated to determine their analytical performance and workflow efficiency in the haematology laboratory. In total 418 samples were processed for determining equivalence of complete blood count (CBC) measurements, and 100 for reticulocyte comparison. Blood smears served for assessing the agreement of the differential counts. Inter-instrument agreement for most parameters was good although small numbers of discrepancies were observed. Systematic biases were found for mean cell volume, reticulocytes, platelets and mean platelet volume. CELL-DYN Ruby WBC differentials were obtained with all samples while the XT-2000i suppressed differentials partially or completely in 13 samples (3.1%). WBC subpopulation counts were otherwise in good agreement with no major outliers. Following first-pass CBC/differential analysis, 88 (21%) of XT-2000i samples required further analyser processing compared to 18 (4.3%) for the CELL-DYN Ruby. Smear referrals for suspected WBC/nucleated red blood cells and platelet abnormalities were indicated for 106 (25.4%) and 95 (22.7%) of the XT-2000i and CELL-DYN Ruby samples respectively. Flagging efficiencies for both analysers were found to be similar. The Sysmex XT-2000i and Abbott CELL-DYN Ruby analysers have broadly comparable analytical performance, but the CELL-DYN Ruby showed superior first-pass efficiency. © 2010 Blackwell Publishing Ltd.
Stability-activity tradeoffs constrain the adaptive evolution of RubisCO.
Studer, Romain A; Christin, Pascal-Antoine; Williams, Mark A; Orengo, Christine A
2014-02-11
A well-known case of evolutionary adaptation is that of ribulose-1,5-bisphosphate carboxylase (RubisCO), the enzyme responsible for fixation of CO2 during photosynthesis. Although the majority of plants use the ancestral C3 photosynthetic pathway, many flowering plants have evolved a derived pathway named C4 photosynthesis. The latter concentrates CO2, and C4 RubisCOs consequently have lower specificity for, and faster turnover of, CO2. The C4 forms result from convergent evolution in multiple clades, with substitutions at a small number of sites under positive selection. To understand the physical constraints on these evolutionary changes, we reconstructed in silico ancestral sequences and 3D structures of RubisCO from a large group of related C3 and C4 species. We were able to precisely track their past evolutionary trajectories, identify mutations on each branch of the phylogeny, and evaluate their stability effect. We show that RubisCO evolution has been constrained by stability-activity tradeoffs similar in character to those previously identified in laboratory-based experiments. The C4 properties require a subset of several ancestral destabilizing mutations, which from their location in the structure are inferred to mainly be involved in enhancing conformational flexibility of the open-closed transition in the catalytic cycle. These mutations are near, but not in, the active site or at intersubunit interfaces. The C3 to C4 transition is preceded by a sustained period in which stability of the enzyme is increased, creating the capacity to accept the functionally necessary destabilizing mutations, and is immediately followed by compensatory mutations that restore global stability.
Metlagel, Zoltan; Kikkawa, Yayoi S; Kikkawa, Masahide
2007-01-01
Helical image analysis in combination with electron microscopy has been used to study three-dimensional structures of various biological filaments or tubes, such as microtubules, actin filaments, and bacterial flagella. A number of packages have been developed to carry out helical image analysis. Some biological specimens, however, have a symmetry break (seam) in their three-dimensional structure, even though their subunits are mostly arranged in a helical manner. We refer to these objects as "asymmetric helices". All the existing packages are designed for helically symmetric specimens, and do not allow analysis of asymmetric helical objects, such as microtubules with seams. Here, we describe Ruby-Helix, a new set of programs for the analysis of "helical" objects with or without a seam. Ruby-Helix is built on top of the Ruby programming language and is the first implementation of asymmetric helical reconstruction for practical image analysis. It also allows easier and semi-automated analysis, performing iterative unbending and accurate determination of the repeat length. As a result, Ruby-Helix enables us to analyze motor-microtubule complexes with higher throughput to higher resolution.
Teaching Financial Literacy with Max and Ruby
ERIC Educational Resources Information Center
Brown, Natalya; Ferguson, Kristen
2017-01-01
Teaching financial literacy is important at all stages of life, but is often neglected with elementary students. In this article, the authors describe a strategy for teaching financial literacy using the books about Max and Ruby by Rosemary Wells. These books can help introduce the five key concepts of financial literacy: scarcity, exchange,…
Lasers: The Magic Wand in Esthetic Dentistry!!
Shajahan, P A; Kumar, P Ranjith; Hariprasad, A; Mathew, Jyothis; Shaji, A P; Ahammed, M Fazeel
2015-01-01
In this era of fast developing technologies and innovative ideas, the need for faster treatment has become a necessity. Treatment with lasers that is much less time-consuming and painless is accepted and appreciated by the patient. Use of Lasers is not new; they have been in use for decades since their development by Maiman in 1960. Lasers have travelled a long way from ruby lasers to erbium lasers and are being fondly used in every aspect of dental treatment. This article aims at elaborate the use and applications of lasers in the field of esthetic dentistry. PMID:26124614
Berger, David L.; Johnson, Michael J.; Tumbusch, Mary L.; Mackay, Jeffrey
2001-01-01
The Ruby Lake National Wildlife Refuge in Ruby Valley, Nevada, contains the largest area of perennial wetlands in northeastern Nevada and provides habitat to a large number of migratory and nesting waterfowl. The long-term preservation of the refuge depends on the availability of sufficient water to maintain optimal habitat conditions. In the Ruby Valley water budget, evapotranspiration (ET) from the refuge is one of the largest components of natural outflow. To help determine the amount of inflow needed to maintain wetland habitat, estimates of ET for May 1999 through October 2000 were made at major habitats throughout the refuge. The Bowen-ratio method was used to estimate daily ET at four sites: over open water, in a moderate-to-dense cover of bulrush marsh, in a moderate cover of mixed phreatophytic shrubs, and in a desert-shrub upland. The eddy-correlation method was used to estimate daily ET for periods of 2 to 12 weeks at a meadow site and at four sites in a sparse-to-moderate cover of phreatophytic shrubs. Daily ET rates ranged from less than 0.010 inch per day at all of the sites to a maximum of 0.464 inch per day at the open-water site. Average daily ET rates estimated for open water and a bulrush marsh were about four to five times greater than in areas of mixed phreatophytic shrubs, where the depth to ground water is less than 5 feet. Based on the seasonal distribution of major habitats in the refuge and on winter and summer ET rates, an estimated total of about 89,000 acre-feet of water was consumed by ET during October 1999-September 2000 (2000 water year). Of this total, about 49,800 acre-feet was consumed by ET in areas of open water and bulrush marsh.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-11
... Intent To Collect Fees on Public Land in Mesa County, CO (Ruby-Horsethief Stretch of the Colorado River... fees for overnight camping on the Ruby-Horsethief stretch of the Colorado River, between Loma, Colorado, and the Colorado State Line, Mesa County, Colorado. The Ruby-Horsethief stretch of the Colorado River...
Development of mRuby2-Transfected C3H10T1/2 Fibroblasts for Musculoskeletal Tissue Engineering
Yang, Yunzhi Peter
2015-01-01
Mouse C3H10T1/2 fibroblasts are multipotent, mesenchymal stem cell (MSC)-like progenitor cells that are widely used in musculoskeletal research. In this study, we have established a clonal population of C3H10T1/2 cells stably-transfected with mRuby2, an orange-red fluorescence reporter gene. Flow cytometry analysis and fluorescence imaging confirmed successful transfection of these cells. Cell counting studies showed that untransfected C3H10T1/2 cells and mRuby2-transfected C3H10T1/2 cells proliferated at similar rates. Adipogenic differentiation experiments demonstrated that untransfected C3H10T1/2 cells and mRuby2-transfected C3H10T1/2 cells stained positive for Oil Red O and showed increased expression of adipogenic genes including adiponectin and lipoprotein lipase. Chondrogenic differentiation experiments demonstrated that untransfected C3H10T1/2 cells and mRuby2-transfected C3H10T1/2 cells stained positive for Alcian Blue and showed increased expression of chondrogenic genes including aggrecan. Osteogenic differentiation experiments demonstrated that untransfected C3H10T1/2 cells and mRuby2-transfected C3H10T1/2 cells stained positive for alkaline phosphatase (ALP) as well as Alizarin Red and showed increased expression of osteogenic genes including alp, ocn and osf-1. When seeded on calcium phosphate-based ceramic scaffolds, mRuby2-transfected C3H10T1/2 cells maintained even fluorescence labeling and osteogenic differentiation. In summary, mRuby2-transfected C3H10T1/2 cells exhibit mRuby2 fluorescence and showed little-to-no difference in terms of cell proliferation and differentiation as untransfected C3H10T1/2 cells. These cells will be available from American Type Culture Collection (ATCC; CRL-3268™) and may be a valuable tool for preclinical studies. PMID:26407291
Development of mRuby2-Transfected C3H10T1/2 Fibroblasts for Musculoskeletal Tissue Engineering.
Ker, Dai Fei Elmer; Sharma, Rashmi; Wang, Evelyna Tsi Hsin; Yang, Yunzhi Peter
2015-01-01
Mouse C3H10T1/2 fibroblasts are multipotent, mesenchymal stem cell (MSC)-like progenitor cells that are widely used in musculoskeletal research. In this study, we have established a clonal population of C3H10T1/2 cells stably-transfected with mRuby2, an orange-red fluorescence reporter gene. Flow cytometry analysis and fluorescence imaging confirmed successful transfection of these cells. Cell counting studies showed that untransfected C3H10T1/2 cells and mRuby2-transfected C3H10T1/2 cells proliferated at similar rates. Adipogenic differentiation experiments demonstrated that untransfected C3H10T1/2 cells and mRuby2-transfected C3H10T1/2 cells stained positive for Oil Red O and showed increased expression of adipogenic genes including adiponectin and lipoprotein lipase. Chondrogenic differentiation experiments demonstrated that untransfected C3H10T1/2 cells and mRuby2-transfected C3H10T1/2 cells stained positive for Alcian Blue and showed increased expression of chondrogenic genes including aggrecan. Osteogenic differentiation experiments demonstrated that untransfected C3H10T1/2 cells and mRuby2-transfected C3H10T1/2 cells stained positive for alkaline phosphatase (ALP) as well as Alizarin Red and showed increased expression of osteogenic genes including alp, ocn and osf-1. When seeded on calcium phosphate-based ceramic scaffolds, mRuby2-transfected C3H10T1/2 cells maintained even fluorescence labeling and osteogenic differentiation. In summary, mRuby2-transfected C3H10T1/2 cells exhibit mRuby2 fluorescence and showed little-to-no difference in terms of cell proliferation and differentiation as untransfected C3H10T1/2 cells. These cells will be available from American Type Culture Collection (ATCC; CRL-3268™) and may be a valuable tool for preclinical studies.
Research progress on laser crystals in China
NASA Astrophysics Data System (ADS)
Yingxia, Z.
1985-01-01
Current Chinese research on laser crystals is now quite extensive and involves more than 30 research teams with nearly 1,000 technicians and workers actively engaged in the study of more than 20 types of laser cyrstals. Neodymium-doped yttrium aluminum garnet (Nd:YAG) and ruby (Cr:Al2O3) lasers have been manufactured and are widely employed. There are several new and promising crystals now under study which will find applications, and both basic and exploratory research have given rise to new developments.
Performance evaluation of Abbott CELL-DYN Ruby for routine use.
Lehto, T; Hedberg, P
2008-10-01
CELL-DYN Ruby is a new automated hematology analyzer suitable for routine use in small laboratories and as a back-up or emergency analyzer in medium- to high-volume laboratories. The analyzer was evaluated by comparing the results from the CELL-DYN((R)) Ruby with the results obtained from CELL-DYN Sapphire . Precision, linearity, and carryover between patient samples were also assessed. Precision was good at all levels for the routine cell blood count (CBC) parameters, CV% being
NASA Technical Reports Server (NTRS)
Jahren, A. H.; Kruger, M. B.; Jeanloz, Raymond
1992-01-01
The wavelength shifts of the R1 and R2 fluorescence lines of alexandrite (BeAl2O4:Cr(+3)) have been experimentally calibrated against the ruby-fluorescence scale as a function of both hydrostatic and nonhydrostatic pressures between 0 and 50 GPa, and simultaneously as a function of temperatures between 290 and 550 K. It is found that the pressure-temperature cross derivative of the fluorescence wavelength shifts are negligible for both ruby and alexandrite.
Laser technology for high precision satellite tracking
NASA Technical Reports Server (NTRS)
Plotkin, H. H.
1974-01-01
Fixed and mobile laser ranging stations have been developed to track satellites equipped with retro-reflector arrays. These have operated consistently at data rates of once per second with range precision better than 50 cm, using Q-switched ruby lasers with pulse durations of 20 to 40 nanoseconds. Improvements are being incorporated to improve the precision to 10 cm, and to permit ranging to more distant satellites. These include improved reflector array designs, processing and analysis of the received reflection pulses, and use of sub-nanosecond pulse duration lasers.
Laser debonding of ceramic brackets: a comprehensive review.
Azzeh, Ezz; Feldon, Paul J
2003-01-01
Since the invention of the ruby laser in the early 1960s, tremendous advances have been made in optic laser technology. Orthodontists have found various uses for lasers, including the debonding of ceramic brackets. Laser energy degrades the adhesive resin used to bond brackets. Consequently, lower forces can be used than when mechanical debonding is performed, reducing the risk of enamel damage. However, the heat produced by some lasers can damage the tooth pulp. Selecting the appropriate laser, resin, and bracket combination can minimize risks and make debonding more efficient. The purpose of this article is to give the clinician an up-to-date, comprehensive literature review about the clinical characteristics of debonding ceramic brackets with lasers.
NASA Astrophysics Data System (ADS)
Penilla, E. H.; Hardin, C. L.; Kodera, Y.; Basun, S. A.; Evans, D. R.; Garay, J. E.
2016-01-01
Light scattering due to birefringence has prevented the use of polycrystalline ceramics with anisotropic optical properties in applications such as laser gain media. However, continued development of processing technology has allowed for very low porosity and fine grains, significantly improving transparency and is paving the way for polycrystalline ceramics to be used in demanding optical applications. We present a method for producing highly transparent Cr3+ doped Al2O3 (ruby) using current activated pressure assisted densification. The one-step doping/densification process produces fine grained ceramics with well integrated (doped) Cr, resulting in good absorption and emission. In order to explain the light transmission properties, we extend the analytical model based on the Rayleigh-Gans-Debye approximation that has been previously used for undoped alumina to include absorption. The model presented captures reflection, scattering, and absorption phenomena in the ceramics. Comparison with measured transmission confirms that the model adequately describes the properties of polycrystalline ruby. In addition the measured emission spectra and emission lifetime are found to be similar to single crystals, confirming the high optical quality of the ceramics.
Arth, Joseph G.; Zmuda, Clara C.; Foley, Nora K.; Criss, Robert E.; Patton, W.W.; Miller, T.P.
1989-01-01
Thirty-six samples from plutons of the Ruby batholith of central Alaska were collected and analyzed for 22 trace elements, and many were analyzed for the isotopic compositions of Sr, Nd, O, and Pb in order to delimit the processes that produced the diversity of granodioritic to granitic compositions, to deduce the nature of the source of magmas at about 110 Ma, and to characterize the deep crust beneath the Ruby and Angayucham terranes. Plutons of the batholith show a substantial range in initial 87Sr/86Sr (SIR) of 0.7055–0.7235 and a general decrease from southwest to northeast. Initial 143Nd/144Nd (NIR) have a range of 0.51150–0.51232 and generally increase from southwest to northeast. The δ18O values for most whole rocks have a range of +8.4 to +11.8 and an average of +10.3‰. Rb, Cs, U, and Th show large ranges of concentration, generally increase as SiO2 increases, and are higher in southwest than in northeast plutons. Sr, Ba, Zr, Hf, Ta, Sc, Cr, Co, and Zr show large ranges of concentration and generally decrease as SiO2 increases. Rare earth elements (REE) show fractionated patterns and negative Eu anomalies. REE concentrations and anomalies are larger in the southwest than in the northeast plutons. Uniformity of SIR and NIR in Sithylemenkat and Jim River plutons suggests a strong role for fractional crystallization or melting of uniform magma sources at depth. Isotopic variability in Melozitna, Ray Mountains, Hot Springs, and Kanuti plutons suggests complex magmatic processes such as magma mixing and assimilation, probably combined with fractional crystallization, or melting of a complex source at depth. The large variations in SIR and NIR in the batholith require a variation in source materials at depth. The southwestern plutons probably had dominantly siliceous sources composed of metamorphosed Proterozoic and Paleozoic upper crustal rocks. The northeastern plutons probably had Paleozoic sources that were mixtures of siliceous and intermediate
Under the Radar: The First Woman in Radio Astronomy, Ruby Payne-Scott
NASA Astrophysics Data System (ADS)
Miller Goss, W.
2012-05-01
Under the Radar, the First Woman in Radio Astronomy, Ruby Payne-Scott W. Miller Goss, NRAO Socorro NM Ruby Payne-Scott (1912-1981) was an eminent Australian scientist who made major contributions to the WWII radar effort (CSIR) from 1941 to 1945. In late 1945, she pioneered radio astronomy efforts at Dover Heights in Sydney, Australia at a beautiful cliff top overlooking the Tasman Sea. Again at Dover Heights, Payne-Scott carried out the first interferometry in radio astronomy using an Australian Army radar antenna as a radio telescope at sun-rise, 26 January 1946. She continued these ground breaking activities until 1951. Ruby Payne-Scott played a major role in discovering and elucidating the properties of Type III bursts from the sun, the most common of the five classes of transient phenomena from the solar corona. These bursts are one of the most intensively studied forms of radio emission in all of astronomy. She is also one of the inventors of aperture synthesis in radio astronomy. I examine her career at the University of Sydney and her conflicts with the CSIR hierarchy concerning the rights of women in the work place, specifically equal wages and the lack of permanent status for married women. I also explore her membership in the Communist Party of Australia as well as her partially released Australian Scientific Intelligence Organization file. Payne-Scott’s role as a major participant in the flourishing radio astronomy research of the post war era remains a remarkable story. She had a number of strong collaborations with the pioneers of early radio astronomy in Australia: Pawsey, Mills, Christiansen, Bolton and Little. I am currently working on a popular version of the Payne-Scott story; “Making Waves, The Story of Ruby Payne-Scott: Australian Pioneer Radio Astronomer” will be published in 2013 by Springer in the Astronomers’ Universe Series.
NASA Astrophysics Data System (ADS)
Bryunetkin, B. A.; Begimkulov, U. Sh; Dyakin, V. M.; Koldashov, G. A.; Repin, A. Yu; Stupitskiĭ, E. L.; Faenov, A. Ya
1993-02-01
The expansion of laser plasmas of the elements Be, Al, Cu, and Pb in a static transverse magnetic field B<=2.7 T has been studied experimentally. The plasma was produced by a ruby laser at a power density no greater than 1012 W/cm2. For all the elements, a characteristic "two-petal" expansion pattern is observed. At a certain distance from the target, the two petals coalesce into a narrow jet. The radius of curvature of the petals and the position of the coalescence point depend on the field strength and the atomic weight of the element.
BioC implementations in Go, Perl, Python and Ruby
Liu, Wanli; Islamaj Doğan, Rezarta; Kwon, Dongseop; Marques, Hernani; Rinaldi, Fabio; Wilbur, W. John; Comeau, Donald C.
2014-01-01
As part of a communitywide effort for evaluating text mining and information extraction systems applied to the biomedical domain, BioC is focused on the goal of interoperability, currently a major barrier to wide-scale adoption of text mining tools. BioC is a simple XML format, specified by DTD, for exchanging data for biomedical natural language processing. With initial implementations in C++ and Java, BioC provides libraries of code for reading and writing BioC text documents and annotations. We extend BioC to Perl, Python, Go and Ruby. We used SWIG to extend the C++ implementation for Perl and one Python implementation. A second Python implementation and the Ruby implementation use native data structures and libraries. BioC is also implemented in the Google language Go. BioC modules are functional in all of these languages, which can facilitate text mining tasks. BioC implementations are freely available through the BioC site: http://bioc.sourceforge.net. Database URL: http://bioc.sourceforge.net/ PMID:24961236
Justin O. Schmidt
2013-01-01
A large artificial sand dune composed of finely crushed mine tailings was produced by deep mining operations at Ruby, Arizona. Today, the ghost town of Ruby is an important historical location and biodiversity refuge, with the newly formed dune forming the core of the refuge. The dune provides ideal nesting habitat for at least 13 species of sand-loving wasps,...
Bibliography of Soviet Laser Developments, Number 89, May-June 1987
1988-04-20
RESEARCH A. Solid State Lasers 1. Crystal a. Miscellaneous ....................... 1 b . Ruby --- c. LiF ................................ 2 2. Rare Earth a...Miscellaneous ....................... 2 b . Nd3+ . ............................... 3 C. Er3+ . ............................... 3 d. Ho3...3 e Tm3+ ---................ 3. Semiconductor a. Theory ............................. 4 b . Miscellaneous Homojunction ...... 4 c
Bibliography of Soviet Laser Developments, No. 17, July - September 1974
1975-01-29
A . N. Tokare and V . M. Usova (0). Effect of structural differ va. ences in flashlamps on the efficiency of solid state lasers...USATYUK, V.V. USHAKOV. A . Yt». USMANOV, A . G. USMANOV, R.G. USOVA , V . M. UZKIY. A . E. VALYASHKO, YE.G. VAREOLOMEYEV. A.A...ot’ power oulpul In a ruby laser with self-Q- switching. ZhPS, v . 20, no. 6, 1974, 987-989. 2, Kopvillem, U. Kh. , V .
Collot, Mayeul; Loukou, Christina; Yakovlev, Aleksey V; Wilms, Christian D; Li, Dongdong; Evrard, Alexis; Zamaleeva, Alsu; Bourdieu, Laurent; Léger, Jean-François; Ropert, Nicole; Eilers, Jens; Oheim, Martin; Feltz, Anne; Mallet, Jean-Maurice
2012-09-12
We designed Calcium Rubies, a family of functionalizable BAPTA-based red-fluorescent calcium (Ca(2+)) indicators as new tools for biological Ca(2+) imaging. The specificity of this Ca(2+)-indicator family is its side arm, attached on the ethylene glycol bridge that allows coupling the indicator to various groups while leaving open the possibility of aromatic substitutions on the BAPTA core for tuning the Ca(2+)-binding affinity. Using this possibility we now synthesize and characterize three different CaRubies with affinities between 3 and 22 μM. Their long excitation and emission wavelengths (peaks at 586/604 nm) allow their use in otherwise challenging multicolor experiments, e.g., when combining Ca(2+) uncaging or optogenetic stimulation with Ca(2+) imaging in cells expressing fluorescent proteins. We illustrate this capacity by the detection of Ca(2+) transients evoked by blue light in cultured astrocytes expressing CatCh, a light-sensitive Ca(2+)-translocating channelrhodopsin linked to yellow fluorescent protein. Using time-correlated single-photon counting, we measured fluorescence lifetimes for all CaRubies and demonstrate a 10-fold increase in the average lifetime upon Ca(2+) chelation. Since only the fluorescence quantum yield but not the absorbance of the CaRubies is Ca(2+)-dependent, calibrated two-photon fluorescence excitation measurements of absolute Ca(2+) concentrations are feasible.
Electron beam physical vapor deposition of thin ruby films for remote temperature sensing
NASA Astrophysics Data System (ADS)
Li, Wei; Coppens, Zachary J.; Greg Walker, D.; Valentine, Jason G.
2013-04-01
Thermographic phosphors (TGPs) possessing temperature-dependent photoluminescence properties have a wide range of uses in thermometry due to their remote access and large temperature sensitivity range. However, in most cases, phosphors are synthesized in powder form, which prevents their use in high resolution micro and nanoscale thermal microscopy. In the present study, we investigate the use of electron beam physical vapor deposition to fabricate thin films of chromium-doped aluminum oxide (Cr-Al2O3, ruby) thermographic phosphors. Although as-deposited films were amorphous and exhibited weak photoluminescence, the films regained the stoichiometry and α-Al2O3 crystal structure of the combustion synthesized source powder after thermal annealing. As a consequence, the annealed films exhibit both strong photoluminescence and a temperature-dependent lifetime that decreases from 2.9 ms at 298 K to 2.1 ms at 370 K. Ruby films were also deposited on multiple substrates. To ensure a continuous film with smooth surface morphology and strong photoluminescence, we use a sapphire substrate, which is thermal expansion coefficient and lattice matched to the film. These thin ruby films can potentially be used as remote temperature sensors for probing the local temperatures of micro and nanoscale structures.
Lasers for tattoo removal: a review.
Choudhary, Sonal; Elsaie, Mohamed L; Leiva, Angel; Nouri, Keyvan
2010-09-01
Tattoos have existed and have been used as an expression of art by man for ages-and so have the techniques to remove them. Lasers based on the principle of selective photothermolysis are now being used to remove black as well as colorful tattoos with varying successes. The commonly used lasers for tattoo removal are the Q-switched 694-nm ruby laser, the Q-switched 755-nm alexandrite laser, the 1,064-nm Nd:YAG laser, and the 532-nm Nd:YAG laser. Newer techniques and methods are evolving in tattoo removal with lasers. Choosing the right laser for the right tattoo color is necessary for a successful outcome. Our review aims to understand the principles of laser tattoo removal and their applications for different types and colors of tattoos. The review also highlights the complications that can occur such as dyspigmentation, allergic reactions, epidermal debris, ink darkening, and so on, in this process and how to prevent them.
RUBI -a Reference mUltiscale Boiling Investigation for the Fluid Science Laboratory
NASA Astrophysics Data System (ADS)
Schweizer, Nils; Stelzer, Marco; Schoele-Schulz, Olaf; Picker, Gerold; Ranebo, Hans; Dettmann, Jan; Minster, Olivier; Toth, Balazs; Winter, Josef; Tadrist, Lounes; Stephan, Peter; Grassi, Walter; di Marco, Paolo; Colin, Catherine; Piero Celata, Gian; Thome, John; Kabov, Oleg
Boiling is a two-phase heat transfer process where large heat fluxes can be transferred with small driving temperature differences. The high performance of boiling makes the process very interesting for heat transfer applications and it is widely used in industry for example in power plants, refrigeration systems, and electronics cooling. Nevertheless, due to the large number of involved phenomena and their often highly dynamic nature a fundamental understanding and closed theoretical description is not yet accomplished. The design of systems incorporating the process is generally based on empirical correlations, which are commonly accompanied by large uncertainties and, thus, has to be verified by expensive test campaigns. Hence, strong efforts are currently made to develop applicable numerical tools for a reliable prediction of the boiling heat transfer performance and limits. In order to support and validate this development and, in particular as a precondition, to enhance the basic knowledge about boiling the comprehensive multi-scale experiment RUBI (Reference mUlti-scale Boiling Investigation) for the Fluid Science Laboratory on board the ISS is currently in preparation. The scientific objectives and requirements of RUBI have been defined by the members of the ESA topical team "Boiling and Multiphase Flow" and addresses fundamental aspects of boiling phenomena. The main objectives are the measurement of wall temperature and heat flux distribution underneath vapour bubbles with high spatial and tem-poral resolution by means of IR thermography accompanied by the synchronized high-speed observation of the bubble shapes. Furthermore, the fluid temperature in the vicinity and inside of the bubbles will be measured by a micro sensor array. Additional stimuli are the generation of an electric field above the heating surface and a shear flow created by a forced convection loop. The objective of these stimuli is to impose forces on the bubbles and investigate the
BioC implementations in Go, Perl, Python and Ruby.
Liu, Wanli; Islamaj Doğan, Rezarta; Kwon, Dongseop; Marques, Hernani; Rinaldi, Fabio; Wilbur, W John; Comeau, Donald C
2014-01-01
As part of a communitywide effort for evaluating text mining and information extraction systems applied to the biomedical domain, BioC is focused on the goal of interoperability, currently a major barrier to wide-scale adoption of text mining tools. BioC is a simple XML format, specified by DTD, for exchanging data for biomedical natural language processing. With initial implementations in C++ and Java, BioC provides libraries of code for reading and writing BioC text documents and annotations. We extend BioC to Perl, Python, Go and Ruby. We used SWIG to extend the C++ implementation for Perl and one Python implementation. A second Python implementation and the Ruby implementation use native data structures and libraries. BioC is also implemented in the Google language Go. BioC modules are functional in all of these languages, which can facilitate text mining tasks. BioC implementations are freely available through the BioC site: http://bioc.sourceforge.net. Database URL: http://bioc.sourceforge.net/ Published by Oxford University Press 2014. This work is written by US Government employees and is in the public domain in the US.
The DV-Xα Calculations of Optical Spectra and Their Pressure-Induced Shifts for Ruby
NASA Astrophysics Data System (ADS)
Ma, Dongping; Ellis, D. E.; Liu, Yanyun; Chen, Jurong
1997-10-01
The R line and U band at normal pressure and their pressure-induced shifts of ruby have been calculated by making use of the SCF embedded-cluster discrete variational (DV-Xα) method. The calculated results of the spectral pressure-induced shifts of ruby by making use of the crystal-field theory have also been given. The results of the first-principle calculations are in very good agreement with the experimental data and the calculated results by using crystal-field theory. The results of local lattice relaxations around the Cr3+ ion are obtained by the DV-Xα calculations. The project supported by National Natural Science Foundation of China
Investigation of laser holographic interferometric techniques for structure inspection
NASA Technical Reports Server (NTRS)
Chu, W. P.
1973-01-01
The application of laser holographic interferometric techniques for nondestructive inspection of material structures commonly used in aerospace works is investigated. Two types of structures, composite plate and solid fuel rocket engine motor casing, were examined. In conducting the experiments, both CW HeNe gas lasers and Q-switched ruby lasers were used as light sources for holographic recording setups. Different stressing schemes were investigated as to their effectiveness in generating maximum deformation at regions of structural weakness such as flaws and disbonds. Experimental results on stressing schemes such as thermal stressing, pressurized stressing, transducer excitation, and mechanical impact are presented and evaluated.
NASA Technical Reports Server (NTRS)
Rodriguez, Juan Jared
2014-01-01
The purpose of this report is to detail the tasks accomplished as a NASA NIFS intern for the summer 2014 session. This internship opportunity is to develop an issue tracker Ruby on Rails web application to improve the communication of developmental anomalies between the Support Software Computer Software Configuration Item (CSCI) teams, System Build and Information Architecture. As many may know software development is an arduous, time consuming, collaborative effort. It involves nearly as much work designing, planning, collaborating, discussing, and resolving issues as effort expended in actual development. This internship opportunity was put in place to help alleviate the amount of time spent discussing issues such as bugs, missing tests, new requirements, and usability concerns that arise during development and throughout the life cycle of software applications once in production.
Satagopan, Sriram; Sun, Yuan; Parquette, Jon R; Tabita, F Robert
2017-01-01
With increasing concerns over global warming and depletion of fossil-fuel reserves, it is attractive to develop innovative strategies to assimilate CO 2 , a greenhouse gas, into usable organic carbon. Cell-free systems can be designed to operate as catalytic platforms with enzymes that offer exceptional selectivity and efficiency, without the need to support ancillary reactions of metabolic pathways operating in intact cells. Such systems are yet to be exploited for applications involving CO 2 utilization and subsequent conversion to valuable products, including biofuels. The Calvin-Benson-Bassham (CBB) cycle and the enzyme ribulose 1,5-bisphosphate carboxylase/oxygenase (RubisCO) play a pivotal role in global CO 2 fixation. We hereby demonstrate the co-assembly of two RubisCO-associated multienzyme cascades with self-assembled synthetic amphiphilic peptide nanostructures. The immobilized enzyme cascades sequentially convert either ribose-5-phosphate (R-5-P) or glucose, a simpler substrate, to ribulose 1,5-bisphosphate (RuBP), the acceptor for incoming CO 2 in the carboxylation reaction catalyzed by RubisCO. Protection from proteolytic degradation was observed in nanostructures associated with the small dimeric form of RubisCO and ancillary enzymes. Furthermore, nanostructures associated with a larger variant of RubisCO resulted in a significant enhancement of the enzyme's selectivity towards CO 2 , without adversely affecting the catalytic activity. The ability to assemble a cascade of enzymes for CO 2 capture using self-assembling nanostructure scaffolds with functional enhancements show promise for potentially engineering entire pathways (with RubisCO or other CO 2 -fixing enzymes) to redirect carbon from industrial effluents into useful bioproducts.
Bibliography of Soviet Laser Developments
1975-09-22
Nagibarov, V. R. , I. A. Nagibarova, and A. M. Shegeda (0). Nonresonant supermigration [of energy ] in concentrated specimens of ruby. ZhETF P...Korniyenko (1). Relationship of luminescence energies of various transitions with the metastable level of the Nd ion in glass. KE, no. 2, 1975...12Ye8) 98. 99. 100. Anan’kin, A. I. (0). Calculating the energy characteriitJcs of a thermally excited CG-, laser. KE, no. 1, 1975
NASA Astrophysics Data System (ADS)
Hilton, B.
2003-12-01
"Operation RubyThroat: The Hummingbird Project" is an international cross-disciplinary initiative that uses Ruby-throated Hummingbirds (Archilochus colubris) as a hook to excite K-12 students (and adults) about science learning. In 2002, Operation RubyThroat affiliated with The GLOBE Program as the first GLOBE protocol that involves animal behavior. Through Operation RubyThroat, students make observations about hummingbird phenology, behavior, and ecology and correlate their data against traditional GLOBE observations of atmosphere, climate, land cover, soils, hydrology, and phenology. Although Ruby-throated Hummingbirds (RTHUs) breed throughout the eastern half of the United States and southern Canada and may be the most common and most widely distributed of all 338 hummingbird species, little is known about how abiotic environmental factors affect their migration, nesting activities, and everyday behavior. Operation RubyThroat participants in the U.S. and Canada log early arrival dates of RTHUs during spring migration, note their presence throughout the breeding season, and report the last date RTHUs are seen in autumn. Conversely, participants in Mexico and all seven Central American countries (the region in which RTHUs spend their non-breeding months) watch for early arrivals in fall and late departures in spring. Participants also attempt to estimate numbers of RTHUs in local populations by counting the number of visits hummingbirds make to feeders and/or flowers in a 45-minute time block. Optional activities include observations of RTHU nesting behaviors and determining RTHU preferences for various species of native and exotic nectar sources. Participating schools are encouraged to establish Schoolyard Hummingbird Habitats in which to make their observations, but data may be collected in backyards or at local parks, nature centers, botanical gardens, and other sites where RTHUs occur. Adults not affiliated with K-12 schools are invited to become certified in
Initiation of insensitive explosives by laser energy
NASA Technical Reports Server (NTRS)
Menichelli, V. J.; Yang, L. C.
1972-01-01
Instantaneous longitudinal detonations were observed in confined columns of pentaerythritol tetranitrate (PETN), cyclotrimethylene trinitramine (RDX), and tetryl when these materials were pulsed with light energy from a focused Q-switch ruby laser. The laser energy ranged from 0.5 to 4.2 J with a pulse width of 25 ns. Enhancement of the ignition mechanism is hypothesized when a 100-nm (1000-A) thick aluminum film is vacuum-deposited on the explosive side of the window. Upon irradiation from the laser, a shock is generated at the aluminum explosive interface. Steady state detonations can be reached in less than 0.5 microseconds with less than 10% variation in detonation velocity for PETN and RDX.
Weight of Production of Emeralds, Rubies, Sapphires, and Tanzanite from 1995 Through 2005
Yager, Thomas R.; Menzie, W. David; Olson, Donald W.
2008-01-01
Comparisons of the weight and the value of production of a type of gemstone between countries may differ considerably. Whereas east African countries dominate the weight production of rubies, Burma (Myanmar) is widely thought to have the highest value of ruby production. Data on the value of gemstone production are even more difficult to estimate than is the weight of production. Value of production is dependent upon both the quality and the sizes of the stones produced. Such data are not readily available and are difficult to estimate; therefore this report does not present tables of values of production. Instead, the report briefly discusses the forms in which gemstones are sold, the systems used to value the gemstones, and selected data that illustrate the variability of value of gemstones of a particular type.
[Agrobacterium rubi strains from blueberry plants are highly diverse].
Abrahamovich, Eliana; López, Ana C; Alippi, Adriana M
2014-01-01
The diversity of a collection of Agrobacterium rubi strains isolated from blueberries from different regions of Argentina was studied by conventional microbiological tests and molecular techniques. Results from biochemical and physiological reactions, as well as from rep-PCR and RFLP analysis of PCR-amplified 23S rDNA showed high phenotypic and genotypic intraspecific variation. Copyright © 2014 Asociación Argentina de Microbiología. Publicado por Elsevier España. All rights reserved.
Bibliography of Soviet Laser Developments, Number 77, May - June 1985.
1986-09-01
B . CONTRACT OR GRANT NUMBER(S) 9. PERFORMING ORGANIZATION NAME AND ADDRESS I0. PROGRAM ELEMENT. PROJECT, TASK Defense Intelligence Agency AREA...TABLE OF CONTENTS I. BASIC RESEARCH A. Solid State Lasers 1. Crystal a. Miscellaneous ................... 1 b . Ruby .. . . . . . . .. . . . . . - c...LiF ............................. 1 2. Rare Earth a. Miscellaneous .......... .. . 1 b . Nd3+ . .. . . . .. . .0 . . . . c. Er3
Ruby and sapphire from Jegdalek, Afghanistan
Bowersox, G.W.; Foord, E.E.; Laurs, B.M.; Shigley, J.E.; Smith, C.P.
2000-01-01
This study provides detailed mining and gemological information on the Jegdalek deposit, in east-central Afghanistan, which is hosted by elongate beds of corundum-bearing marble. Some facet-grade ruby has been recovered, but most of the material consists of semitransparent pink sapphire of cabochon or carving quality. The most common internal features are dense concentrations of healed and nonhealed fracture planes and lamellar twin planes. Color zoning is common, and calcite, apatite, zircon, mica, iron sulfide minerals, graphite, rutile, aluminum hydroxide, and other minerals are also present in some samples. Although the reserves appear to be large, future potential will depend on the establishment of a stable government and the introduction of modern mining and exploration techniques. ?? 2000 Gemological Institute of America.
Peddling Poverty for Profit: Elements of Oppression in Ruby Payne's Framework
ERIC Educational Resources Information Center
Gorski, Paul C.
2008-01-01
Ruby Payne, CEO of aha! Process, Inc., and author of "A Framework for Understanding Poverty" (2005), has become one of the most influential figures in the U.S. public education milieu. Payne's framework, built largely upon understanding the "culture" of poverty, instructs educators on the values and mindsets poor students carry into the classroom…
A dual-cavity ruby maser for the Ka-band link experiment
NASA Technical Reports Server (NTRS)
Shell, J.; Quinn, R. B.
1994-01-01
A 33.68-GHz dual-cavity ruby maser was built to support the Ka-Band Link Experiment (KABLE) conducted with the Mars Observer spacecraft. It has 25 dB of net gain and a 3-dB bandwidth of 85 MHz. Its noise temperature in reference to the cooled feedhorn aperture is 5 K.
Gadolinium Scandium Gallium Garnet (GSGG) as a Solid-State Laser Host
1987-07-01
o*SATI CODSi1.SBEC EM (otne nrvrs fnceayad dniy nb)k ubr ~~~~~~~~ Gadolinium Scandium Gallium Garnet (GSGG)asaSldtteLerHt 17. ABSTRACT 6.SUJCTTEM...certain other garnet materials for replacement. It also addresses the solid-state laser host material Gadolinium Scandium Gal- lium Garnet (GSGG) and its...by neodymium-doped yttrium aluminum garnet (Nd:YAG) or other mate- rials for most applications. In the years after the invention of the ruby laser, in
Kretzschmar, D; Poeck, B; Roth, H; Ernst, R; Keller, A; Porsch, M; Strauss, R; Pflugfelder, G O
2000-01-01
Lysosomal protein trafficking is a fundamental process conserved from yeast to humans. This conservation extends to lysosome-like organelles such as mammalian melanosomes and insect eye pigment granules. Recently, eye and coat color mutations in mouse (mocha and pearl) and Drosophila (garnet and carmine) were shown to affect subunits of the heterotetrameric adaptor protein complex AP-3 involved in vesicle trafficking. Here we demonstrate that the Drosophila eye color mutant ruby is defective in the AP-3beta subunit gene. ruby expression was found in retinal pigment and photoreceptor cells and in the developing central nervous system. ruby mutations lead to a decreased number and altered size of pigment granules in various cell types in and adjacent to the retina. Humans with lesions in the related AP-3betaA gene suffer from Hermansky-Pudlak syndrome, which is caused by defects in a number of lysosome-related organelles. Hermansky-Pudlak patients have a reduced skin pigmentation and suffer from internal bleeding, pulmonary fibrosis, and visual system malfunction. The Drosophila AP-3beta adaptin also appears to be involved in processes other than eye pigment granule biogenesis because all ruby allele combinations tested exhibited defective behavior in a visual fixation paradigm. PMID:10790396
Gross, Andreas J; Herrmann, Thomas R W
2007-06-01
The developments of laser technology from the cradle of modern physics in 1900 by Planck to its latest medical boundaries is an exciting example of how basic physics finds its way into clinical practice. This article merits the protagonists and their contribution to the steps in this development. The competition between the different research groups finally led to the award of the Nobel Prize to Townes, Basov and Prokhorov in 1964 for the scientific basis on quantum electronics, which led to the construction of oscillators and amplifiers based on the laser-maser principle. Forty-three years after Einstein's first theories Maiman introduced the first ruby laser for commercial use. This marked the key step for the laser application and pioneered fruitful cooperations between basic and clinical science. The pioneers of lasers in clinical urology were Parsons in 1966 with studies in canine bladders and Mulvany 1968 with experiments in calculi fragmentation. The central technological component for the triumphal procession of lasers in urology is the endoscope. Therefore lasers are currently widely used, being the tool of choice in some areas, such as endoscopical lithotriptic stone treatment or endoluminal organ-preserving tumor ablation. Furthermore they show promising treatment alternatives for the treatment of benign prostate hyperplasia.
Laser techniques in high-pressure geophysics
NASA Technical Reports Server (NTRS)
Hemley, R. J.; Bell, P. M.; Mao, H. K.
1987-01-01
Laser techniques in conjunction with the diamond-anvil cell can be used to study high-pressure properties of materials important to a wide range of problems in earth and planetary science. Spontaneous Raman scattering of crystalline and amorphous solids at high pressure demonstrates that dramatic changes in structure and bonding occur on compression. High-pressure Brillouin scattering is sensitive to the pressure variations of single-crystal elastic moduli and acoustic velocities. Laser heating techniques with the diamond-anvil cell can be used to study phase transitions, including melting, under deep-earth conditions. Finally, laser-induced ruby fluorescence has been essential for the development of techniques for generating the maximum pressures now possible with the diamond-anvil cell, and currently provides a calibrated in situ measure of pressure well above 100 gigapascals.
Influence of modified atmosphere packaging on 'Star Ruby' grapefruit phytochemicals.
Chaudhary, Priyanka R; Jayaprakasha, G K; Porat, Ron; Patil, Bhimanagouda S
2015-01-28
Modified atmosphere packaging (MAP) can extend the shelf life of salads, vegetables, and fruits by generating a storage environment with low O2, high CO2, and high humidity. The current study investigates the effect of modified atmosphere and humidity generated by two plastic films, microperforated bags (MIPBs) and macroperforated bags (MAPBs), on the levels of phytochemicals present in 'Star Ruby' grapefruits (Citrus paradisi, Macf.) stored for 16 weeks at 10 °C. Control fruits were stored without any packaging film. Juice samples were analyzed every 4 weeks for ascorbic acid, carotenoids, limonoids, flavonoids, and furocoumarins and assessed for quality parameters. MAP significantly reduced weight loss compared to control grapefruits. Control fruits had more β-carotene, lycopene, and furocoumarin compared with the fruits in MAP. Flavonoid content was highest in fruits stored in MAPB (P < 0.05), while fruits stored in MIPB showed no significant difference in flavonoid content compared to control (P > 0.05). The MAP treatments did not significantly affect ascorbic acid, limonoids, or fruit quality parameters, including total soluble solids, acidity, ripening ratio, decay and disorders, fruit taste, and off-flavors after 16 weeks of storage. These results suggest that MAP can be used to maintain the quality of 'Star Ruby' grapefruit with no detrimental effect on health-promoting phytochemicals.
Effect of fusion mixture treatment on the surface of low grade natural ruby
NASA Astrophysics Data System (ADS)
Sakthivel, R.; Pradhan, K. C.; Nayak, B. B.; Dash, Tapan; Sahu, R. K.; Mishra, B. K.
2017-05-01
Improvement in aesthetic look of low grade natural ruby (gemstone) surface was clearly evident after fusion mixture treatment. Surface impurities of the gemstone were significantly reduced to give it a face lift. The processing consists of heat treatment (1000 °C) of the raw gemstone with fusion mixture (sodium and potassium carbonates), followed by hydrochloric acid digestion (90 °C) and ultrasonic cleaning.Both the untreated and the treated gemstone were characterized by X-ray diffraction, UV-vis spectroscopy (diffuse reflectance),photoluminescence and X-ray photoelectron spectroscopy. The paper consolidates the results of these studies and presents the effect of the typical chemical treatment (stated above) on the low grade natural ruby. While X-ray diffraction study identifies the occurrence of alumina phase in both the treated and the untreated gemstones, the UV-vis spectra exhibit strong characteristic absorption of Cr3+at 400 and 550 nm wavelength for the treated gemstone in contrast to weak absorption observed for the untreated gemstone at such wavelengths, thus showing the beneficial effect of fusion mixture treatment. Peaks observed for the gemstone (for both treated and untreated samples) in the excitation spectra of photoluminescence show a good correlation with observed UV-vis (diffuse reflectance) spectra. Photoluminescence emission spectra of the untreated gemstone show characteristic emission at 695 nm for Cr3+ ion (as in alumina matrix), but its emission intensity significantly reduces after fusion mixture treatment. It is found that the surface of the fusion mixture treated ruby gemstone looks much brighter than the corresponding untreated surface.
Blaz, Jacquelyn W; Pearce, Patricia F
2009-01-01
The world is becoming increasingly web-based. Health care institutions are utilizing the web for personal health records, surveillance, communication, and education; health care researchers are finding value in using the web for research subject recruitment, data collection, and follow-up. Programming languages, such as Java, require knowledge and experience usually found only in software engineers and consultants. The purpose of this paper is to demonstrate Ruby on Rails as a feasible alternative for programming questionnaires for use on the web. Ruby on Rails was specifically designed for the development, deployment, and maintenance of database-backed web applications. It is flexible, customizable, and easy to learn. With a relatively little initial training, a novice programmer can create a robust web application in a small amount of time, without the need of a software consultant. The translation of the Children's Computerized Physical Activity Reporter (C-CPAR) from a local installation in Microsoft Access to a web-based format utilizing Ruby on Rails is given as an example.
Removal of a glowing spot from an image tube using laser radiation.
NASA Technical Reports Server (NTRS)
Gurski, T. R.
1972-01-01
A troublesome problem with the Kron electronograph has been the presence of a white glowing spot on the glass wall of the tube adjacent to the focus electrode. The procedure followed to eliminate the spot was to operate in the dark and apply voltage only to the focused electrode. Ruby laser radiation was unfocused, and its position was shifted on the electrode between laser shots until an effect was observed. This technique for removing the glowing spot should be applicable to other electronic image tubes.
Infinite projected entangled-pair state algorithm for ruby and triangle-honeycomb lattices
NASA Astrophysics Data System (ADS)
Jahromi, Saeed S.; Orús, Román; Kargarian, Mehdi; Langari, Abdollah
2018-03-01
The infinite projected entangled-pair state (iPEPS) algorithm is one of the most efficient techniques for studying the ground-state properties of two-dimensional quantum lattice Hamiltonians in the thermodynamic limit. Here, we show how the algorithm can be adapted to explore nearest-neighbor local Hamiltonians on the ruby and triangle-honeycomb lattices, using the corner transfer matrix (CTM) renormalization group for 2D tensor network contraction. Additionally, we show how the CTM method can be used to calculate the ground-state fidelity per lattice site and the boundary density operator and entanglement entropy (EE) on an infinite cylinder. As a benchmark, we apply the iPEPS method to the ruby model with anisotropic interactions and explore the ground-state properties of the system. We further extract the phase diagram of the model in different regimes of the couplings by measuring two-point correlators, ground-state fidelity, and EE on an infinite cylinder. Our phase diagram is in agreement with previous studies of the model by exact diagonalization.
Liu, Minrui; Lin, Pengwu; Qi, Xing'e; Ni, Yongqing
2016-04-14
The purpose of the study was to reveal geographic region-related Acidithiobacillus spp. distribution and allopatric speciation. Phylogenetic and diversity analysis was done to expand our knowledge on microbial phylogeography, diversity-maintaining mechanisms and molecular biogeography. We amplified 16S rRNA gene and RubisCO genes to construct corresponding phylogenetic trees based on the sequence homology and analyzed genetic diversity of Acidithiobacillus spp.. Thirty-five strains were isolated from three different regions in China (Yunnan, Hubei, Xinjiang). The whole isolates were classified into five groups. Four strains were identified as A. ferrivorans, six as A. ferridurans, YNTR4-15 Leptspirillum ferrooxidans and HBDY3-31 as Leptospirillum ferrodiazotrophum. The remaining strains were identified as A. ferrooxidans. Analysis of cbbL and cbbM genes sequences of representative 26 strains indicated that cbbL gene of 19 were two copies (cbbL1 and cbbL2) and 7 possessed only cbbL1. cbbM gene was single copy. In nucleotide-based trees, cbbL1 gene sequences of strains were separated into three sequence types, and the cbbL2 was similar to cbbL1 with three types. Codon bias of RubisCO genes was not obvious in Acidithiobacillus spp.. Strains isolated from three different regions in China indicated a great genetic diversity in Acidithiobacillus spp. and their 16S rRNA/RubisCO genes sequence was of significant difference. Phylogenetic tree based on 16S rRNA genes and RubisCO genes was different in Acidithiobacillus spp..
Whole genome sequences of the raspberry and strawberry pathogens Phytophthora rubi and P. fragariae
USDA-ARS?s Scientific Manuscript database
Phytophthora rubi and P. fragariae are two closely related oomycete plant pathogens that exhibit strong morphological and physiological similarities, but are specialized to infect different hosts of economic importance, namely raspberry and strawberry. Here, we report the draft genome sequences of t...
Nonradiative relaxation in tunable solid state laser crystals
NASA Technical Reports Server (NTRS)
Gayen, S. K.; Wang, W. B.; Petricevic, V.; Alfano, R. R.
1986-01-01
The characteristics of nonradiative transitions between the 4T2 and 2E excited states of trivalent-chromium-ion-activated ruby (containing 0.04 percent Cr2O3 by weight) and alexandrite (containing 0.4 at. percent chromium ion) laser crystals were studied using the technique described by Gayen et al. (1985). In this technique, a 527-nm pulse excites the 4T2 band of the Cr(3+), and the subsequent population kinetics among excited states is monitored by an IR picosecond probe pulse as a function of pump-probe delay. In ruby, a resolution-limited sharp rise in the excited state population was followed by a long-lifetime decay, leading to an upper limit of 7 ps for the 4T2-state nonradiative lifetime. In alexandrite, a longer rise time was followed by a multicomponent decay. A theoretical model is proposed for explaining the induced absorption and the transition dynamics observed in these crystals.
Geology of the north end of the Ruby Range, southwestern Montana
Tysdal, Russell G.
1970-01-01
This study consists of two parts: stratigraphy and sedimentation, and structure of rocks in the northern one-third of the Ruby Range of southwestern Montana. Detailed studies of Cambrian marine dolomite rocks in the Red Lion Formation and in the upper part of the Pilgrim Limestone resulted in their division into distinct rock units, termed lithofacies. These lithofacies contain features suggestive of subtidal, intertidal, and supratidal environments similar to those presently forming in the Persian Gulf. Stromatolltic structures occurring in the uppermost part of the Red Lion Formation are similar to those presently forming in Shark Bay, Australia. The Ruby Range within the map area is broken into a series of northwest-plunging basement (Precambrian metamorphic rock) blocks, differentially uplifted during the Cretaceous-Tertiary orogenic period. These blocks are bordered by upthrust faults, which are nearly vertical in their lower segments and are .low-angle in their uppermost parts. Asymmetrical folds in Paleozoic sedimentary rocks formed in response to the differential uplift of the blocks; thus they too plunge to the northwest. Displaced masses of rock border the range on the three sides within the map area and are interpreted as gravity-slide features resulting from uplift of the range. Normal faulting began blocking out the present range margins by Oligocene time.
Evolution of basin and range structure in the Ruby Mountains and vicinity, Nevada
NASA Technical Reports Server (NTRS)
Blackwell, D. D.; Reese, N. M.; Kelley, S. A.
1985-01-01
Results from various age dating techniques, seismic reflection profiling hydrocarbon maturation studies, and structural analysis were used to evaluate the Cenozoic deformation in the Ruby Mountains and adjoining ranges (pinyon Range and Cortez Range) in Elko and Eureka Counties, Nevada. Age dating techniques used include potassium-argon ages of biotites from granites published by Kistler et al. (1981) and fission track ages from apatite and zircon. Fission track ages from apatite reflect a closing temperature of 100 plus or minus 20 deg C. Zircon fission track ages reflect a closing temperature of 175 plus or minus 25 deg C and potassium-argon ages from brotite reflect a closing temperature of 250 plus or minus 30 deg C. Thus these results allow a reasonably precise tracking of the evolution of the ranges during the Cenozoic. Seismic reflection data are available from Huntington Valley. Access to seismic reflection data directly to the west of the Harrison Pass Pluton in the central Ruby Mountains was obtained. In addition results are available from several deep exploration holes in Huntington Valley.
NASA Astrophysics Data System (ADS)
Sanchez, J. L.; Osipowicz, T.; Tang, S. M.; Tay, T. S.; Win, T. T.
1997-07-01
The trace element concentrations found in geological samples can shed light on the formation process. In the case of gemstones, which might be of artificial or natural origin, there is also considerable interest in the development of methods that provide identification of the origin of a sample. For rubies, trace element concentrations present in natural samples were shown previously to be significant indicators of the region of origin [S.M. Tang et al., Appl. Spectr. 42 (1988) 44, and 43 (1989) 219]. Here we report the results of micro-PIXE analyses of trace element (Ti, V, Cr, Fe, Cu and Ga) concentrations of a large set ( n = 130) of natural rough rubies from nine locations in Myanmar (Burma). The resulting concentrations are subjected to statistical analysis. Six of the nine groups form clusters when the data base is evaluated using tree clustering and principal component analysis.
Desjardin, Dennis E; Hemmes, Don E; Perry, Brian A
2014-01-01
Pseudobaeospora wipapatiae is described as new based on material collected in alien wet habitats on the island of Hawaii. Unique features of this beautiful species include deep ruby-colored basidiomes with two-spored basidia, amyloid cheilocystidia and a hymeniderm pileipellis with abundant pileocystidia that is initially deep ruby in KOH then changes to lilac gray. Phylogenetic analysis of nuclear large ribosomal subunit sequence data suggest a close relationship between Pseudobaeospora and Tricholoma. BLAST comparisons of internal transcribed spacer and 5.8S nuclear ribosomal subunit regions sequence data reveal greatest similarity with existing sequences of Pseudobaeospora species. A comprehensive description, color photograph, illustrations of salient micromorphological features and comparisons with phenetically similar taxa are provided. © 2014 by The Mycological Society of America.
NASA Astrophysics Data System (ADS)
Karube, Norio
1991-03-01
I am to report on some aspects of industrial lasers in Japan. Mostly centering on the market. In Japan, the history of laser developnent is rather profound. And long. Ever since the first invention of the laser in this country in 1960. This is partly because of the fact that in Japan the spectroscopic studies of the ruby was very popular in the late 1950's. Ever since niost of the work has been done in the research laboratories of the industry, not in the universities or not in the governmental laboratories. And since that time our first activity was mainly centering on the basic research, but after that time we have the evolution of the technology. One of the features in Japan is that the activity of developement and research of laser technology from the very basic phase up to the present commercialization has been done by the same group of people, including ine. We had a national project which ended about six years ago which was sponsored by MITI. MITI is Ministry of International Trade and Industry in Japan. And because of this national project, the effect of this project had a very enlightening effect in Japan. And after that our Japanese laser market became very flourishing.
Laser ignition of traumatically embedded firework debris.
Taylor, C R
1998-01-01
The Q-switched ruby laser (QSRL) has a good track record for traumatic tattoo removal. An unusual case of QSRL-treatment of a traumatic tattoo composed of firework debris is presented. A young man's traumatic tattoo, composed of firework debris, underwent QSRL ablation at 4-7 J/cm2 (pulse width 5 mm; duration 20 ns). Each test pulse produced visible sparks and focal projectile ejection of skin with pox-like scar formation. Caution is advised when using the QSRL for the treatment of traumatic tattoos composed of potentially combustible debris.
Bibliography of Soviet Laser Developments, Number 23, January - March 1976
1976-09-15
A . N. Tokareva, and V . M. Usova 0). Exper*nental study of the effect of a ...VORONIN, A .!1. 76 J1 USHAKOV. V . T. 53 VORONOV, V . V . 100 USHKOV, F. V . 93 VOROSHILOV, YU. V . 94 USOL’TSEV, 1. F. 23 VOYTENKO, A . M. 99 USOVA , V : M...131 I IC ’I tA 11 V I. BASIC RESEARCH I A . SOLID STATE LASERS 1. Crystal: Ruby 1. Agashkov, A . V ., L. A . Lavrovskiy,
1978-10-17
characteristics for optical second- harmonic generation. The collage component of conective tissue may be the principal site for the observed harmonic...Generation in Tissue ; Second Harmonic Generation in Collage; Glutathione, 5MB; Mechanisms; Conversion Efficiency; Significance of order UL AIM UY#m~wmev...sclera, and skin on 694 im. Q-switched ruby laser irradiation. A possible source of this second-harmonic generation was tissue collagen; because of
Lasers for Frontier Spectroscopy
NASA Astrophysics Data System (ADS)
Baldacchini, Giuseppe
The first laser has been invented in 1960 by using the red light from a ruby crystal, and since then the laser field exploded almost exponentially, and thousands of different materials, in the state of solids, liquids, vapors, gases, plasmas, and elementary particles have lased up to now from less than I Å to more than 1 mm. Many of them have been used with outstanding results both in basic science, and in industrial and commercial applications, by changing for ever the same lifestyle of humankind. As far as spectroscopy is concerned, the laser light has started an unprecedented revolution because of its unique properties as monochromaticity, coherence, power, brightness and short-pulse regime, unrivaled by any other natural and artificial light source. Spectroscopy applications increased qualitatively and quantitatively with the laser sources themselves, and they are still proceeding in parallel with the moving of the laser field towards new territories. Apart the opening up of new regions of the electromagnetic spectrum, like the terahertz gap, and the outstanding increase of the output power which is giving rise to completely new spectroscopic effects, the improvement of laser sources and auxiliary equipment is producing a growth of traditional laser spectroscopy with superior resolution and sensitivity. Moreover, spectroscopic techniques and laser light contributed to the development of new chemical and physical processes which have been used to fabricate photonic materials with new spectroscopic properties enriching the laser field itself, in a virtuous cycle spectroscopy→aser→material and back to spectroscopy with no end in sight.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-05
...; MO 4500051040; TAS: 14X5017] Notice of Availability of the Draft Supplemental Environmental Impact... Availability. SUMMARY: In accordance with the National Environmental Policy Act of 1969, as amended (NEPA), and...) has prepared a Draft Supplemental Environmental Impact Statement (EIS) for the Ruby Pipeline Project...
NASA Astrophysics Data System (ADS)
Peterka, Pavel; Navrátil, Petr; Dussardier, Bernard; Slavík, Radan; Honzátko, Pavel; Kubecek, Václav
2012-06-01
Rare-earth doped fiber lasers are subject to instabilities and various self-pulsed regimes that can lead to catastrophic damage of their components. An interesting self-pulsing regime accompanied with laser wavelength drift with time is the so called self-induced laser line sweeping (SLLS). Despite the early observations of the SLLS in solid-state ruby lasers, in fiber lasers it was first time mentioned in literature only in 2009 where such a laser wavelength drift with time was observed in a relatively broad range of about 1076 -1084 nm in ring ytterbium-doped fiber laser (YDFL). The main characteristic of the SLLS is the scanning of the laser wavelength from shorter to longer wavelength, spanning over large interval of several nanometers, and instantaneous bounce backward. The period of this sweeping is usually quite long, of the order of seconds. This spectacular effect was attributed to spatial-hole burning caused by standing-wave in the laser cavity. In this paper we present experimental investigation of the SLLS in YDFLs in Fabry-Perot cavity and ring cavities. The SLLS was observed also in erbium-doped fiber laser around 1560 nm. We present for the first time observation of the laser wavelength sweep in reverse direction, i.e., from longer towards shorter wavelengths. It was observed in YDFL around 1080 nm.
NASA Astrophysics Data System (ADS)
2008-09-01
ESO's Wide Field Imager has captured the intricate swirls of the spiral galaxy Messier 83, a smaller look-alike of our own Milky Way. Shining with the light of billions of stars and the ruby red glow of hydrogen gas, it is a beautiful example of a barred spiral galaxy, whose shape has led to it being nicknamed the Southern Pinwheel. Messier 83, M83 ESO PR Photo 25/08 Spiral Galaxy Messier 83 This dramatic image of the galaxy Messier 83 was captured by the Wide Field Imager at ESO's La Silla Observatory, located high in the dry desert mountains of the Chilean Atacama Desert. Messier 83 lies roughly 15 million light-years away towards the huge southern constellation of Hydra (the sea serpent). It stretches over 40 000 light-years, making it roughly 2.5 times smaller than our own Milky Way. However, in some respects, Messier 83 is quite similar to our own galaxy. Both the Milky Way and Messier 83 possess a bar across their galactic nucleus, the dense spherical conglomeration of stars seen at the centre of the galaxies. This very detailed image shows the spiral arms of Messier 83 adorned by countless bright flourishes of ruby red light. These are in fact huge clouds of glowing hydrogen gas. Ultraviolet radiation from newly born, massive stars is ionising the gas in these clouds, causing the great regions of hydrogen to glow red. These star forming regions are contrasted dramatically in this image against the ethereal glow of older yellow stars near the galaxy's central hub. The image also shows the delicate tracery of dark and winding dust streams weaving throughout the arms of the galaxy. Messier 83 was discovered by the French astronomer Nicolas Louis de Lacaille in the mid 18th century. Decades later it was listed in the famous catalogue of deep sky objects compiled by another French astronomer and famous comet hunter, Charles Messier. Recent observations of this enigmatic galaxy in ultraviolet light and radio waves have shown that even its outer desolate regions
Laser-assisted hair removal for facial hirsutism in women: A review of evidence.
Lee, Chun-Man
2018-06-01
Poly cystic ovarian syndrome (PCOS) has been described as the common diagnosis for hirsutism in women. Facial hirsutism is by far the most distressing symptom of hyperandrogenism in women with PCOS. A statistically significant improvement in psychological well-being has been reported in patients with PCOS allocated for laser-assisted hair removal. The theory of selective photothermolysis has revolutionized laser hair removal in that it is effective and safe, when operated by sufficiently trained and experienced professionals. Long-pulsed ruby (694 nm), long-pulsed alexandrite (755 nm), diode (800-980 nm), and long-pulsed Nd:YAG (1064 nm) are commercially available laser devices for hair removal most widely studied. This article will introduce the fundamentals and mechanism of action of lasers in hair removal, in a contemporary literature review looking at medium to long term efficacy and safety profiles of various laser hair removal modalities most widely commercially available to date.
Light and Laser Modalities in the Treatment of Cutaneous Sarcoidosis: A Systematic Review.
Lima, Ana Luiza; Goetze, Steven; Illing, Tanja; Elsner, Peter
2018-04-27
Sarcoidosis is a systemic non-caseating granulomatous disease of unknown aetiology. Cutaneous manifestations are present in approximately 10-30% of the patients with the systemic form. Therapy is indicated in case of disabling symptoms, organ dysfunction or cosmetically distressing manifestation. Despite different therapeutic possibilities, cutaneous sarcoidosis remains exceptionally difficult to treat. Light and laser therapy may be a promising alternative. In this systematic review, we summarised the available treatments according to the literature concerning light and laser therapy for cutaneous sarcoidosis. Publications written in English and German, published between January 1990 and July 2016 in the database PubMed, MEDLINE, Embase, and Scopus were analysed. Light therapy with intense pulsed light, photodynamic therapy, and ultraviolet A light therapy, as well as laser therapy with pulsed dye laser, YAG laser, and Q-switched ruby laser were described. The results are based on individual case reports and small case series. Randomised controlled studies are lacking.
Path toward a high-energy solid-state laser
NASA Astrophysics Data System (ADS)
Wood, Gary L.; Merkle, Larry D.; Dubinskii, Mark; Zandi, Bahram
2004-04-01
Lasers have come a long way since the first demonstration by Maiman of a ruby crystal laser in 1960. Lasers are used as scientific tools as well as for a wide variety of applications for both commercial industry and the military. Today lasers come in all types, shapes and sizes depending on their application. The solid-state laser has some distinct advantages in that it can be rugged, compact, and self contained, making it reliable over long periods of time. With the advent of diode laser pumping a ten times increase in overall laser efficiency has been realized. This significant event, and others, is changing the way solid-state lasers are applied and allows new possibilities. One of those new areas of exploration is the high energy laser. Solid-state lasers for welding are already developed and yield energies in the 0.5 to 6 kilojoule range. These lasers are at the forefront of what is possible in terms of high energy solid-state lasers. It is possible to achieve energies of greater than 100 kJ. These sorts of energies would allow applications, in addition to welding, such as directed energy weapons, extremely remote sensing, power transfer, propulsion, biological and chemical agent neutralization and unexploded and mine neutralization. This article will review these new advances in solid-state lasers and the different paths toward achieving a high energy laser. The advantages and challenges of each approach will be highlighted.
NASA Astrophysics Data System (ADS)
Peng, Qian; Juzeniene, Asta; Chen, Jiyao; Svaasand, Lars O.; Warloe, Trond; Giercksky, Karl-Erik; Moan, Johan
2008-05-01
It is hard to imagine that a narrow, one-way, coherent, moving, amplified beam of light fired by excited atoms is powerful enough to slice through steel. In 1917, Albert Einstein speculated that under certain conditions atoms could absorb light and be stimulated to shed their borrowed energy. Charles Townes coined the term laser (light amplification by stimulated emission of radiation) in 1951. Theodore Maiman investigated the glare of a flash lamp in a rod of synthetic ruby, creating the first human-made laser in 1960. The laser involves exciting atoms and passing them through a medium such as crystal, gas or liquid. As the cascade of photon energy sweeps through the medium, bouncing off mirrors, it is reflected back and forth, and gains energy to produce a high wattage beam of light. Although lasers are today used by a large variety of professions, one of the most meaningful applications of laser technology has been through its use in medicine. Being faster and less invasive with a high precision, lasers have penetrated into most medical disciplines during the last half century including dermatology, ophthalmology, dentistry, otolaryngology, gastroenterology, urology, gynaecology, cardiology, neurosurgery and orthopaedics. In many ways the laser has revolutionized the diagnosis and treatment of a disease. As a surgical tool the laser is capable of three basic functions. When focused on a point it can cauterize deeply as it cuts, reducing the surgical trauma caused by a knife. It can vaporize the surface of a tissue. Or, through optical fibres, it can permit a doctor to see inside the body. Lasers have also become an indispensable tool in biological applications from high-resolution microscopy to subcellular nanosurgery. Indeed, medical lasers are a prime example of how the movement of an idea can truly change the medical world. This review will survey various applications of lasers in medicine including four major categories: types of lasers, laser
Intracavity optically controlled crystal modulators for a CO/sub 2/ laser
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chizhevskii, V.N.; Churakov, V.V.
1986-06-01
This paper presents the results of studies of intracavity amplitude modulation of CW CO/sub 2/ laser radiation by its optically controlled absorption on nonequilibrium charge carriers (NCC) in KRS-5, KRS-6, and ZnSe crystals. The fundamental variables which determine the efficiency of such a modulation method are discussed. The radiation from a ruby laser with a 35-nsec pulse width was used to produce the nonequilibrium charge carriers. The variation of the modulation percentage of the intensity vs. excitation level at lambda = 0.6943 ..mu..m is shown for different powers of the CO/sub 2/ laser. The studies attest to the relatively highmore » efficiency of intracavity modulation based on IR radiation absorption by NCC in crystals, where the NCC are generated under the influence of external excitation.« less
The Cascading Impacts of Technology Selection: Incorporating Ruby on Rails into ECHO
NASA Astrophysics Data System (ADS)
Pilone, D.; Cechini, M.
2010-12-01
NASA’s Earth Observing System (EOS) ClearingHOuse (ECHO) is a SOA based Earth Science Data search and order system implemented in Java with one significant exception: the web client used by 98% of our users is written in Perl. After several decades of maintenance the Perl based application had reached the end of its serviceable life and ECHO was tasked with implementing a replacement. Despite a broad investment in Java, the ECHO team conducted a survey of modern development technologies including Flex, Python/Django, JSF2/Spring and Ruby on Rails. The team ultimately chose Ruby on Rails (RoR) with Cucumber for testing due to its perceived applicability to web application development and corresponding development efficiency gains. Both positive and negative impacts on the entire ECHO team, including our stakeholders, were immediate and sometimes subtle. The technology selection caused shifts in our architecture and design, development and deployment procedures, requirement definition approach, testing approach, and, somewhat surprisingly, our project team structure and software process. This presentation discusses our experiences, including technical, process, and psychological, using RoR on a production system. During this session we will discuss: - Real impacts of introducing a dynamic language to a Java team - Real and perceived efficiency advantages - Impediments to adoption and effectiveness - Impacts of transition from Test Driven Development to Behavior Driven Development - Leveraging Cucumber to provide fully executable requirement documents - Impacts on team structure and roles
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-20
... effects of the construction and operation of the following project facilities: About 675.2 miles of 42... any of the following methods: Web site: http://www.blm.gov/nv/st/en/info/nepa/ruby_pipeline_project...
Production of gold and ruby-red lustres in Gubbio (Umbria, Italy) during the Renaissance period
NASA Astrophysics Data System (ADS)
Padeletti, G.; Fermo, P.
The aim of this work is to gain a further insight into the knowledge of the production process of lustre-decorated ancient majolicas. Lustre is a sophisticated technique employed in the decoration of majolicas as used in central Italy during the Renaissance period. It consists of a beautiful iridescent gold or ruby-red thin metallic film, containing silver, copper and other substances and obtained in a reducing atmosphere on a previously glazed ceramic. Nowadays, it is not possible to replicate the outstanding results obtained by the ancient ceramicists, since the original recipes were lost. It is quite interesting to study lustre-production technology by means of analytical techniques now employed for advanced research on materials (XRD, ETAAS, ICP-OES, TEM-EDX-SAED and UV-Vis). In this work, we have focussed our attention on ceramic fragments decorated with both gold and ruby-red lustres, which were difficult to obtain due to complex reduction conditions required and which were a prerogative of Gubbio production. The two lustre colours differ in their chemical composition as well in their nanostructure. The presence of bismuth was disclosed and it was ascertained to be a distinctive feature of the Italian production.
Standard guidelines of care: laser and IPL hair reduction.
Buddhadev, Rajesh M
2008-01-01
Laser-assisted hair removal, Laser hair removal, Laser and light-assisted hair removal, Laser and light-assisted, long-term hair reduction, IPL photodepilation, LHE photodepilation; all these are acceptable synonyms. Laser (Ruby, Nd Yag, Alexandrite, Diode), intense pulse light, light and heat energy system are the different light-/Laser-based systems used for hair removal; each have its advantages and disadvantages. The word "LONG-TERM HAIR REDUCTION" should be used rather than permanent hair removal. Patient counseling is essential about the need for multiple sessions. PHYSICIANS' QUALIFICATIONS: Laser hair removal may be practiced by any dermatologist, who has received adequate background training during postgraduation or later at a centre that provides education and training in Lasers or in focused workshops providing such training. The dermatologist should have adequate knowledge of the machines, the parameters and aftercare. The physician may allow the actual procedure to be performed under his/her direct supervision by a trained nurse assistant/junior doctor. However, the final responsibility for the procedure would lie with the physician. The procedure may be performed in the physician's minor procedure room. Investigations to rule out any underlying cause for hair growth are important; concurrent drug therapy may be needed. Laser parameters vary with area, type of hair, and the machine used. Full knowledge about the machine and cooling system is important. Future maintenance treatments may be needed.
Selby, D.; Kelley, K.D.; Hitzman, M.W.; Zieg, J.
2009-01-01
New Re-Os data for chalcopyrite, bornite, and pyrite from the carbonate-hosted Cu deposit at Ruby Creek (Bornite), Alaska, show extremely high Re abundances (hundreds of ppb, low ppm) and contain essentially no common Os. The Re-Os data provide the first absolute ages of ore formation for the carbonate-hosted Ruby Creek Cu-(Co) deposit and demonstrate that the Re-Os systematics of pyrite, chalcopyrite, and bornite are unaffected by greenschist metamorphism. The Re-Os data show that the main phase of Cu mineralization pre dominantly occurred at 384 ?? 4.2 Ma, with an earlier phase possibly at ???400 Ma. The Re-Os data are consistent with the observed paragenetic sequence and coincide with zircon U-Pb ages from igneous rocks within the Ambler metallogenic belt, some of which are spatially and genetically associated with regional volcanogenic massive sulfide deposits. The latter may suggest a temporal link between regional magmatism and hydrothermal mineralization in the Ambler district. The utility of bornite and chalcopyrite, in addition to pyrite, contributes to a new understanding of Re-Os geochronology and permits a refinement of the genetic model for the Ruby Creek deposit. ?? 2009 Society of Economices Geologists, Inc.
Nilforoushzadeh, Mohammad Ali; Naieni, Farahnaz Fatemi; Siadat, Amir Hossein; Rad, Leila
2011-11-01
Laser systems that are commonly used for the treatment of hirsutism include the ruby laser (694 nm), the diode laser (800 nm), the alexandrite laser (755 nm) and the Nd:YAG laser (1084 nm). The diode laser and alexandrite laser are considered effective in treatment of hirsutism in dark-skinned patients. The response of hairs to these laser systems is variable and not complete. In this study, we compared the efficacy of these two laser systems for permanent hair removal. This was a randomized, controlled clinical trial that was performed with women of the age range 15-45 years old. After obtaining informed consent, the samples were randomized into two groups using random allocation software. The first group was treated with alexandrite laser alone (four sessions, two months apart). The second group was treated sequentially with diode laser for the first two sessions and alexandrite laser for the next two sessions. Overall, 111 patients (57 patients in the alexandrite laser group and 54 patients in the sequential diode-alexandrite laser group) were evaluated. There was no significant difference regarding mean of hair reduction between the two groups during the courses of treatment. Except for the first session, there was no significant difference regarding percent of patient satisfaction between the two groups (P value >0.05). Comparison between the two groups showed no significant difference one month, three months and six months after the last treatment (P value >0.05). Regarding the results of our study, there is no significant difference between sequential treatment with diode and alexandrite lasers versus alexandrite laser alone in the treatment of hirsutism. We suggest that in further studies, the efficacy of sequential treatment with other laser systems is evaluated against single treatment methods.
Observations on Bubble Dynamics at High Pressures and Bubble Dynamics in Stagnation Flow.
1982-11-30
reverse side It nocooeuAn aifdentifly by block mt..bet) S 1 Cavitation, High Speed Photography, Ruby Laser . 20. AFSTAACT Co.nflno on revere side Of...AT NIGH ASIE3r.T PRESSUrES A.T. Ellis and J.E. Starrect University of California, San Diego Recent developsent by the authors of a unique ruby laser ...1,000,300 frames per second with exposure clue of approximately 2vl0- seconds. The coherent nature of the laser illuminacion revealed shock waves
Code of Federal Regulations, 2011 CFR
2011-01-01
... PEWTER INDUSTRIES § 23.23 Misuse of the words “ruby,” “sapphire,” “emerald,” “topaz,” “stone...,” “emerald,” “topaz,” or the name of any other precious or semi-precious stone to describe any product that... “ruby,” “sapphire,” “emerald,” “topaz,” or the name of any other precious or semi-precious stone, or the...
Code of Federal Regulations, 2013 CFR
2013-01-01
... PEWTER INDUSTRIES § 23.23 Misuse of the words “ruby,” “sapphire,” “emerald,” “topaz,” “stone...,” “emerald,” “topaz,” or the name of any other precious or semi-precious stone to describe any product that... “ruby,” “sapphire,” “emerald,” “topaz,” or the name of any other precious or semi-precious stone, or the...
Code of Federal Regulations, 2010 CFR
2010-01-01
... PEWTER INDUSTRIES § 23.23 Misuse of the words “ruby,” “sapphire,” “emerald,” “topaz,” “stone...,” “emerald,” “topaz,” or the name of any other precious or semi-precious stone to describe any product that... “ruby,” “sapphire,” “emerald,” “topaz,” or the name of any other precious or semi-precious stone, or the...
Code of Federal Regulations, 2012 CFR
2012-01-01
... PEWTER INDUSTRIES § 23.23 Misuse of the words “ruby,” “sapphire,” “emerald,” “topaz,” “stone...,” “emerald,” “topaz,” or the name of any other precious or semi-precious stone to describe any product that... “ruby,” “sapphire,” “emerald,” “topaz,” or the name of any other precious or semi-precious stone, or the...
Code of Federal Regulations, 2014 CFR
2014-01-01
... PEWTER INDUSTRIES § 23.23 Misuse of the words “ruby,” “sapphire,” “emerald,” “topaz,” “stone...,” “emerald,” “topaz,” or the name of any other precious or semi-precious stone to describe any product that... “ruby,” “sapphire,” “emerald,” “topaz,” or the name of any other precious or semi-precious stone, or the...
USDA-ARS?s Scientific Manuscript database
Root rot of raspberry (Rubus idaeus), thought to be primarily caused by Phytophthora rubi, is an economically important disease in the western United States. The objectives of this study were to determine which Phytophthora species are involved in root rot, examine the efficacy of different isolatio...
NASA Technical Reports Server (NTRS)
Uchino, O.; Tabata, T.; Akita, I.; Okada, Y.; Naito, K.
1985-01-01
Large amounts of aerosol particles and gases were injected into the lower stratosphere by the violet volcanic eruptions of El Chichon on March 28, and April 3 and 4, 1982. Observational results obtained by a ruby lidar at Tsukuba (36.1 deg N, 140.1 deg E) are shown, and some points of latitude dispersion processes of aerosols are discussed.
Zenzal, Theodore J; Contina, Andrea J; Kelly, Jeffrey F; Moore, Frank R
2018-01-01
Autumn latitudinal migrations generally exhibit one of two different temporal migration patterns: type 1 where southern populations migrate south before northern populations, or type 2 where northern populations overtake southern populations en route . The ruby-throated hummingbird ( Archilochus colubris ) is a species with an expansive breeding range, which allows opportunities to examine variation in the timing of migration. Our objective was to determine a relationship between natal origin of ruby-throated hummingbirds and arrival at a Gulf coast stopover site; and if so, what factors, such as differences in body size across the range as well as the cost of migration, might drive such a pattern. To carry out our objectives, we captured hummingbirds at a coastal stopover site during autumn migration, at which time we collected feathers from juveniles for analysis of hydrogen stable isotopes. Using the hydrogen stable isotope gradient of precipitation across North America and published hydrogen isotope values of feathers from populations of breeding ruby-throated hummingbirds, we assigned migrants to probable natal latitudes. Our results confirm that individuals from across the range (30-50° N) stopover along the Gulf of Mexico and there is a positive relationship between arrival day and latitude, suggesting a type 1 migration pattern. We also found no relationship between fuel load (proxy for migration cost) or fat-free body mass (proxy for body size) and natal latitude. Our results, coupled with previous work on the spatial migration patterns of hummingbirds, show a type 1 chain migration pattern. While the mechanisms we tested do not seem to influence the evolution of migratory patterns, other factors such as resource availability may play a prominent role in the evolution of this migration system.
Snoke, A.W.; Howard, K.A.; McGrew, A.J.; Burton, B.R.; Barnes, C.G.; Peters, M.T.; Wright, J.E.
1997-01-01
The purpose of this geological excursion is to provide an overview of the multiphase developmental history of the Ruby Mountains and East Humboldt Range, northeastern Nevada. Although these mountain ranges are commonly cited as a classic example of a Cordilleran metamorphic core complex developed through large-magnitude, mid-Tertiary crustal extension, a preceding polyphase Mesozoic contractional history is also well preserved in the ranges. An early phase of this history involved Late Jurassic two-mica granitic magmatism, high-temperature but relatively low-pressure metamorphism, and polyphase deformation in the central Ruby Mountains. In the northern Ruby Mountains and East Humboldt Range, a Late Cretaceous history of crustal shortening, metamorphism, and magmatism is manifested by fold-nappes (involving Archean basement rocks in the northern East Humboldt Range), widespread migmatization, injection of monzogranitic and leucogranitic magmas, all coupled with sillimanite-grade metamorphism. Following Late Cretaceous contraction, a protracted extensional deformation partially overprinted these areas during the Cenozoic. This extensional history may have begun as early as the Late Cretaceous or as late as the mid-Eocene. Late Eocene and Oligocene magmatism occurred at various levels in the crust yielding mafic to felsic orthogneisses in the deep crust, a composite granitic pluton in the upper crust, and volcanic rocks at the surface. Movement along a west-rooted, extensional shear zone in the Oligocene and early Miocene led to core-complex exhumation. The shear zone produced mylonitic rocks about 1 km thick at deep crustal levels, and an overprint of brittle detachment faulting at shallower levels as unroofing proceeded. Megabreccias and other synextensional sedimentary deposits are locally preserved in a tilted, upper Eocene through Miocene stratigraphic sequence. Neogene magmatism included the emplacement of basalt dikes and eruption of rhyolitic rocks. Subsequent
Berggren, K; Chernokalskaya, E; Steinberg, T H; Kemper, C; Lopez, M F; Diwu, Z; Haugland, R P; Patton, W F
2000-07-01
SYPRO Ruby dye is a permanent stain comprised of ruthenium as part of an organic complex that interacts noncovalently with proteins. SYPRO Ruby Protein Gel Stain provides a sensitive, gentle, fluorescence-based method for detecting proteins in one-dimensional and two-dimensional sodium dodecyl sulfate-polyacrylamide gels. Proteins are fixed, stained from 3h to overnight and then rinsed in deionized water or dilute methanol/acetic acid solution for 30 min. The stain can be visualized using a wide range of excitation sources commonly used in image analysis systems including a 302 nm UV-B transilluminator, 473 nm second harmonic generation (SHG) laser, 488 nm argon-ion laser, 532 nm yttrium-aluminum-garnet (YAG) laser, xenon arc lamp, blue fluorescent light bulb or blue light-emitting diode (LED). The sensitivity of SYPRO Ruby Protein Gel Stain is superior to colloidal Coomassie Brilliant Blue (CBB) stain or monobromobimane labeling and comparable with the highest sensitivity silver or zinc-imidazole staining procedures available. The linear dynamic range of SYPRO Ruby Protein Gel stain extends over three orders of magnitude, which is vastly superior to silver, zinc-imidazole, monobromobimane and CBB stain. The fluorescent stain does not contain superfluous chemicals (formaldehyde, glutaraldehyde, Tween-20) that frequently interfere with peptide identification in mass spectrometry. While peptide mass profiles are severely altered in protein samples prelabeled with monobromobimane, successful identification of proteins by peptide mass profiling using matrix-assisted laser desorption/ionization mass spectrometry was easily performed after protein detection with SYPRO Ruby Protein Gel stain.
The g Factors of Ground State of Ruby and Their Pressure-Induced Shifts
NASA Astrophysics Data System (ADS)
Ma, Dongping; Zhang, Hongmei; Chen, Jurong; Liu, Yanyun
1998-12-01
By using the theory of pressure-induced shifts and the eigenfunctions at normal and various pressures obtained from the diagonalization of the complete d3 energy matrix adopting C3v symmetry, g factors of the ground state of ruby and their pressure-induced shifts have been calculated. The results are in very good agreement with the experimental data. For the precise calculation of properties of the ground skate, it is necessary to take into account the effects of all the excited states by the diagonalization of the complete energy matrix. The project (Grant No. 19744001) supported by National Natural Science Foundation of China
Ownby, Gary W.; White, Clark W.; Zehner, David M.
1981-01-01
This invention relates to a new method for removing surface impurities from crystalline silicon or germanium articles, such as off-the-shelf p- or n-type wafers to be doped for use as junction devices. The principal contaminants on such wafers are oxygen and carbon. The new method comprises laser-irradiating the contaminated surface in a non-reactive atmosphere, using one or more of Q-switched laser pulses whose parameters are selected to effect melting of the surface without substantial vaporization thereof. In a typical application, a plurality of pulses is used to convert a surface region of an off-the-shelf silicon wafer to an automatically clean region. This can be accomplished in a system at a pressure below 10.sup.-8 Torr, using Q-switched ruby-laser pulses having an energy density in the range of from about 60 to 190 MW/cm.sup.2.
NASA Astrophysics Data System (ADS)
Ando, Takahiro; Sato, Shunichi; Ashida, Hiroshi; Obara, Minoru
2013-07-01
Laser-induced stress waves (LISWs) generated by irradiating a light-absorbing medium with a pulsed laser can transiently increase the permeability of cell membranes for gene delivery. In this study, we investigated the effects of pressure characteristics of LISWs upon gene transfection efficiency using lasers with different pulse durations: a 6-ns pulsed Nd:YAG laser and 20-ns and 200-µs pulsed ruby lasers. LISWs were generated by irradiating a black rubber disk, on which a transparent plastic sheet was adhered for confinement of the laser-produced plasma. Rat dorsal skin was injected with plasmid DNA coding for luciferase, to which LISWs were applied. With nanosecond laser pulses, transfection efficiency increased linearly with increasing positive peak pressure in the range of 35 to 145 MPa, the corresponding impulse ranging from 10 to 40 Paṡs. With 200-µs laser pulses, on the other hand, efficient gene expression was observed by the application of LISWs even with a 10-fold-lower peak pressure (˜5 MPa), the corresponding impulse being as large as 430 Paṡs. These results indicate that even at low peak pressures, efficient transfection can be achieved by extending the pressure duration and hence by increasing the impulse of LISWs, while the averaged expression efficiencies were relatively low.
Picosecond excite-and-probe absorption measurement of the 4T2 state nonradiative lifetime in ruby
NASA Technical Reports Server (NTRS)
Gayen, S. K.; Wang, W. B.; Petricevic, V.; Dorsinville, R.; Alfano, R. R.
1985-01-01
In a picosecond excite-and-probe absorption measurement, a 527-nm picosecond pulse excites the 4T2 state of the Cr(3+) ion in ruby and a 3.4-micron picosecond probe pulse monitors the growth and decay of population in the 2E state as a function of pump-probe delay. From the growth of population in the metastable 2E state, an upper limit of 7 ps for the nonradiative lifetime of the 4T2 state is determined.
Aird, Gregory A; Sitenga, Jenna L; Nguyen, Austin Huy; Vaudreuil, Adam; Huerter, Christopher J
2017-05-01
Treatment of disseminated superficial actinic porokeratosis (DSAP) is poorly standardized. The present review seeks to comprehensively discuss the potential for laser and light modalities in the treatment of DSAP. A systematic review of light and laser treatment modalities was conducted to include 26 cases of patients with DSAP. Systematic review resulted in 14 articles to be included. Photodynamic therapy (PDT) overall was the least successful treatment modality, with clinical improvement seen in a minority of patients (MAL-PDT: N = 9 patients, 33.3% showed improvement; ALA-PDT: N = 3 patients, 0% improvement; hypericin-PDT: N = 2 patients, 0% improvement) after numerous post-procedural side effects of hyperpigmentation, inflammation, erythema, and discomfort. Overall, in the available reports, PDT demonstrates poor outcomes with greater incidence of side effects. The response rates of DSAP lesions treated with lasers were as follows: (Q-switched ruby lasers: N = 2, 100%; CO 2 laser: N = 1, 100%; PDT and CO 2 combination therapy: N = 2, 0-50%; erbium and neodymium YAG lasers: N = 2, 100%; fractional 1927-nm thulium fiber lasers: N = 2, 100%; Grenz rays: N = 1, 100%; and fractional photothermolysis: N = 2, 100%). The side effects of laser therapy were minimal and included mild erythema, slight hyperpigmentation, and moderate edema. Laser therapy is a promising treatment option for DSAP with an excellent side effect profile. However, higher power studies are required to determine optimal guidelines for laser treatment of DSAP.
Clinical dental application of Er:YAG laser for Class V cavity preparation.
Matsumoto, K; Nakamura, Y; Mazeki, K; Kimura, Y
1996-06-01
Following the development of the ruby laser by Maiman in 1960, the Nd:YAG laser, the CO2 laser, the semiconductor laser, the He-Ne laser, excimer lasers, the argon laser, and finally the Er:YAG laser capable of cutting hard tissue easily were developed and have come to be applied clinically. In the present study, the Er:YAG laser emitting at a wavelength of 2.94 microns developed by Luxar was used for the clinical preparation of class V cavities. Parameters of 8 Hz and approx. 250 mJ/pulse maximum output were used for irradiation. Sixty teeth of 40 patients were used in this clinical study. The Er:YAG laser used in this study was found to be a system suitable for clinical application. No adverse reaction was observed in any of the cases. Class V cavity preparation was performed without inducing any pain in 48/60 cases (80%). All of the 12 cases that complained of mild or severe intraoperative pain had previously complained of cervical dentin hypersensibility during the preoperative examination. Cavity preparation was completed with this laser system in 58/60 cases (91.7%). No treatment-related clinical problems were observed during the follow-up period of approx. 30 days after cavity preparation and resin filling. Cavity preparation took between approx. 10 sec and 3 min and was related more or less to cavity size and depth. Overall clinical evaluation showed no safety problem with very good rating in 49 cases (81.7%).
Underwater Test Diagnostics Using Explosively Excited Argon And Laser Light Photography Techniques
NASA Astrophysics Data System (ADS)
Wisotski, John
1990-01-01
This paper presents results of photographic methods employed in underwater tests used to study high-velocity fragment deceleration, deformation and fracture during the perforation of water-backed plates. These methods employed overlapping ultra-high and very high speed camera recordings using explosively excited argon and ruby-laser light sources that gave ample light to penetrate across a 2.3-meter (7.54-foot) diameter tank of water with enough intensity to photograph displacement-time histories of steel cubes with impact speeds of 1000 to 1500 m/s (3280 to 4920 ft/s) at camera framing rates of 250,000 and 17,000 fr/s, respectively.
NASA Astrophysics Data System (ADS)
Diddens, Heyke C.; Gillies, Robert; Hasan, Tayyaba
1994-08-01
Benzoporphyrin derivative, monoacid ring A (BPD-MA) is a second generation porphyrin photosensitizer, with a significant absorption at 692 nm. The ability of two different lasers (a high-intensity pulsed ruby laser, and a continuous wave (cw) argon-ion laser pumped dye laser) in producing photodynamic damage to human bladder carcinoma cells in vitro under similar conditions was compared. Cells incubated in 0.14 (mu) M BPD-MA for 3 hours were irradiated with 1 or 3 J/cm2 with either pulsed or cw irradiation at 694 nm. Cell survival was determined using an MTT assay. With the ruby laser essentially no phototoxicity was observed at the high intensity pulsed irradiances used, whereas 38% and 6% survival rates were observed for 1 and 3 J/cm2, respectively, using cw irradiation. Possible explanations for the lack of BPD-MA phototoxicity using the ruby laser are: rapid photodegradation, saturation and excitation into higher excited states of the sensitizer. No BPD-MA photodegradation was observed in 1.4 (mu) M BPD-MA in 10% fetal calf serum solutions using the ruby laser. However, an oxygen-dependent photodegradation with the formation of a chlorin-type photoproduct was observed in these solutions using cw irradiation. A simple calculation indicated that the high pulse irradiances used in this study (4.4 X 107 W/cm2) were approximately 3 orders of magnitude greater than required for the onset of saturation. If higher excited states (Sn or Tn) are populated, they do not undergo any photochemistry resulting in phototoxicity or in photoproduct formation. These results show that with the low saturation threshold of BPD-MA, the choice of source and irradiance are important considerations in planning a therapeutic regime.
The measurement of atmospheric visibility with Lidar: TSC field test results
DOT National Transportation Integrated Search
1974-03-01
The report represents a technical feasibility study of the use of lidar for determining the atmospheric extinction coefficient in low visibility. Measurements were made with three laser sources: a Q-switched ruby laser, a GaAlAs diode laser array, an...
Crowley, J.K.; Brickey, D.W.; Rowan, L.C.
1989-01-01
Airborne imaging spectrometer data collected in the near-infrared (1.2-2.4 ??m) wavelength range were used to study the spectral expression of metamorphic minerals and rocks in the Ruby Mountains of southwestern Montana. The data were analyzed by using a new data enhancement procedure-the construction of relative absorption band-depth (RBD) images. RBD images, like bandratio images, are designed to detect diagnostic mineral absorption features, while minimizing reflectance variations related to topographic slope and albedo differences. To produce an RBD image, several data channels near an absorption band shoulder are summed and then divided by the sum of several channels located near the band minimum. RBD images are both highly specific and sensitive to the presence of particular mineral absorption features. Further, the technique does not distort or subdue spectral features as sometimes occurs when using other data normalization methods. By using RBD images, a number of rock and soil units were distinguished in the Ruby Mountains including weathered quartz - feldspar pegmatites, marbles of several compositions, and soils developed over poorly exposed mica schists. The RBD technique is especially well suited for detecting weak near-infrared spectral features produced by soils, which may permit improved mapping of subtle lithologic and structural details in semiarid terrains. The observation of soils rich in talc, an important industrial commodity in the study area, also indicates that RBD images may be useful for mineral exploration. ?? 1989.
Effects of Process Parameters on Ultrasonic Micro-Hole Drilling in Glass and Ruby
DOE Office of Scientific and Technical Information (OSTI.GOV)
Schorderet, Alain; Deghilage, Emmanuel; Agbeviade, Kossi
2011-05-04
Brittle materials such as ceramics, glasses and oxide single crystals find increasing applications in advanced micro-engineering products. Machining small features in such materials represents a manufacturing challenge. Ultrasonic drilling constitutes a promising technique for realizing simple micro-holes of high diameter-to-depth ratio. The process involves impacting abrasive particles in suspension in a liquid slurry between tool and work piece. Among the process performance criteria, the drilling time (productivity) is one of the most important quantities to evaluate the suitability of the process for industrial applications.This paper summarizes recent results pertaining to the ultrasonic micro-drilling process obtained with a semi-industrial 3-axis machine.more » The workpiece is vibrated at 40 kHz frequency with an amplitude of several micrometers. A voice-coil actuator and a control loop based on the drilling force impose the tool feed. In addition, the tool is rotated at a prescribed speed to improve the drilling speed as well as the hole geometry. Typically, a WC wire serves as tool to bore 200 {mu}m diameter micro-holes of 300 to 1,000 {mu}m depth in glass and ruby. The abrasive slurry contains B4C particles of 1 {mu}m to 5 {mu}m diameter in various concentrations.This paper discusses, on the basis of the experimental results, the influence of several parameters on the drilling time. First, the results show that the control strategy based on the drilling force allows to reach higher feed rates (avoiding tool breakage). Typically, a 8 um/s feed rate is achieved with glass and 0.9 {mu}m/s with ruby. Tool rotation, even for values as low as 50 rpm, increases productivity and improves holes geometry. Drilling with 1 {mu}m and 5 {mu}m B4C particles yields similar productivity results. Our future research will focus on using the presented results to develop a model that can serve to optimize the process for different applications.« less
Lasers as an approach for promoting drug delivery via skin.
Lin, Chih-Hung; Aljuffali, Ibrahim A; Fang, Jia-You
2014-04-01
Using lasers can be an effective drug permeation-enhancement approach for facilitating drug delivery into or across the skin. The controlled disruption and ablation of the stratum corneum (SC), the predominant barrier for drug delivery, is achieved by the use of lasers. The possible mechanisms of laser-assisted drug permeation are the direct ablation of the skin barrier, optical breakdown by a photomechanical wave and a photothermal effect. It has been demonstrated that ablative approaches for enhancing drug transport provide some advantages, including increased bioavailability, fast treatment time, quick recovery of SC integrity and the fact that skin surface contact is not needed. In recent years, the concept of using laser techniques to treat the skin has attracted increasing attention. This review describes recent developments in using nonablative and ablative lasers for drug absorption enhancement. This review systematically introduces the concepts and enhancement mechanisms of lasers, highlighting the potential of this technique for greatly increasing drug absorption via the skin. Lasers with different wavelengths and types are employed to increase drug permeation. These include the ruby laser, the erbium:yttrium-gallium-garnet laser, the neodymium-doped yttrium-aluminum-garnet laser and the CO2 laser. Fractional modality is a novel concept for promoting topical/transdermal drug delivery. The laser is useful in enhancing the permeation of a wide variety of permeants, such as small-molecule drugs, macromolecules and nanoparticles. This potential use of the laser affords a new treatment for topical/transdermal application with significant efficacy. Further studies using a large group of humans or patients are needed to confirm and clarify the findings in animal studies. Although the laser fluence or output energy used for enhancing drug absorption is much lower than for treatment of skin disorders and rejuvenation, the safety of using lasers is still an issue
Revisiting the temperature dependence of the homogeneous R 1 linewidth in ruby
NASA Astrophysics Data System (ADS)
Riesen, Hans; Szabo, Alex
2010-01-01
Transient spectral-hole-burning studies of the R 1(±3/2) line ( E¯ ( 2E) ← 4A 2(±3/2)) in 20 ppm ruby were conducted between 2.4 and 50 K in a low magnetic field ( B|| = 9.15 mT) and the results were supplemented with the original data of McCumber and Sturge. A direct one-phonon process, 2A¯←E¯, is the main contribution to the linewidth up to 50 K whereas at higher temperatures two-phonon Raman scattering becomes dominant. The two processes are well described by ΔΓdirect=Γ0/(exp(Δ/kT)-1) and a non-perturbative expression for the electron-phonon interaction developed by Hsu and Skinner. The value of Γ0 = 141 (±4) MHz is in excellent agreement with the result of 142 ± 6 MHz previously obtained for the R 2 line.
NASA Astrophysics Data System (ADS)
Bertolotti, M.
2010-09-01
On July, 7, 1960 a press conference at Huyghes announced that Maiman had assembled and put into operation the first laser. It was the very pulsed ruby laser that everybody knows today. The announcement came as a bomb. Nobody expected that in an unknown laboratory, new to the race to build a laser, this result could be obtained. It was such an unexpected result that many still today mantain that the true laser was discovered at Bell by Shawlow. This result was achieved through a long story which passed by the Townes maser and many tentative experiments and discussions both in the USA and Soviet Union. In this special issue we present a collection of papers which provide further information as to what happened after Einstein introduced the concept of stimulated emission. The first paper is a short paper by Townes on the development of the physics of microwaves following the creation of the maser. When the laser came on the stage one of its properties was the inherent coherence of the emitted light. Emil Wolf's contribution enlights the early days of coherence to which he so much contributed and the very timely first Rochester Conference which was held on June 27-29, 1960 a few days before the Times announcement of the Maiman achievement. Important contributions were given by Soviet Scientists and, Svetlana Lukishova's contributions helps us understand the work of Valentin Fabrikant which was mostly unknown to western scientists. At the end of his life, Maiman went to Vancouver in Canada and Andrew H. Rawicz gives his testimoniancy of his friendship there. Coherence and the statistical properties of laser light were much studied and we have two exceptional papers by Roy Pike and Jan Perina discussing these arguments. The issue also contains three more papers presenting some earlier achievements in the construction of multiquantumwell laser (M. L. Dotor, P. Huertas, P. A. Postigo, D. Golmayo and F. Briones), the first measurements on very short pulses (H. P. Weber and
Michielsen, K.; De Raedt, H.; Stavenga, D. G.
2010-01-01
We present a comparison of the computer simulation data of gyroid nanostructures with optical measurements (reflectivity spectra and scattering diagrams) of ventral wing scales of the Green Hairstreak butterfly, Callophrys rubi. We demonstrate that the omnidirectional green colour arises from the gyroid cuticular structure grown in the domains of different orientation. We also show that this three-dimensional structure, operating as a biophotonic crystal, gives rise to various polarization effects. We briefly discuss the possible biological utility of the green coloration and polarization effects. PMID:19828506
Michielsen, K; De Raedt, H; Stavenga, D G
2010-05-06
We present a comparison of the computer simulation data of gyroid nanostructures with optical measurements (reflectivity spectra and scattering diagrams) of ventral wing scales of the Green Hairstreak butterfly, Callophrys rubi. We demonstrate that the omnidirectional green colour arises from the gyroid cuticular structure grown in the domains of different orientation. We also show that this three-dimensional structure, operating as a biophotonic crystal, gives rise to various polarization effects. We briefly discuss the possible biological utility of the green coloration and polarization effects.
NASA Astrophysics Data System (ADS)
Wilgus, J. T.; Schmandt, B.; Jiang, C.
2017-12-01
The relative importance of potential controls on crustal seismic anisotropy, such as deformational fabrics in polycrystalline crustal rocks and the contemporary state of stress, remain poorly constrained. Recent regional western US lithospheric seismic anisotropy studies have concluded that the distribution of strain in the lower crust is diffuse throughout the Basin and Range (BR) and that deformation in the crust and mantle are largely uncoupled. To further contribute to our understanding of crustal anisotropy we are conducting a detailed local study of seismic anisotropy within the BR using surface waves at the Ruby Mountain Core Complex (RMCC), located in northeast Nevada. The RMCC is one of many distinctive uplifts within the North American cordillera called metamorphic core complexes which consist of rocks exhumed from middle to lower crustal depths adjacent to mylonitic shear zones. The RMCC records exhumation depths up to 30 km indicating an anomalously high degree of extension relative to the BR average. This exhumation, the geologic setting of the RMCC, and the availability of dense broadband data from the Transportable Array (TA) and the Ruby Mountain Seismic Experiment (RMSE) coalesce to form an ideal opportunity to characterize seismic anisotropy as a function of depth beneath RMCC and evaluate the degree to which anisotropy deviates from regional scale properties of the BR. Preliminary azimuthal anisotropy results using Rayleigh waves reveal clear anisotropic signals at periods between 5-40 s, and demonstrate significant rotations of fast orientations relative to prior regional scale results. Moving forward we will focus on quantification of depth-dependent radial anisotropy from inversion of Rayleigh and Love waves. These results will be relevant to identification of the deep crustal distribution of strain associated with RMCC formation and may aid interpretation of controls on crustal anisotropy in other regions.
N and Cr ion implantation of natural ruby surfaces and their characterization
NASA Astrophysics Data System (ADS)
Rao, K. Sudheendra; Sahoo, Rakesh K.; Dash, Tapan; Magudapathy, P.; Panigrahi, B. K.; Nayak, B. B.; Mishra, B. K.
2016-04-01
Energetic ions of N and Cr were used to implant the surfaces of natural rubies (low aesthetic quality). Surface colours of the specimens were found to change after ion implantation. The samples without and with ion implantation were characterized by diffuse reflectance spectra in ultra violet and visible region (DRS-UV-Vis), field emission scanning electron microscopy (FESEM), selected area electron diffraction (SAED) and nano-indentation. While the Cr-ion implantation produced deep red surface colour (pigeon eye red) in polished raw sample (without heat treatment), the N-ion implantation produced a mixed tone of dark blue, greenish blue and violet surface colour in the heat treated sample. In the case of heat treated sample at 3 × 1017 N-ions/cm2 fluence, formation of colour centres (F+, F2, F2+ and F22+) by ion implantation process is attributed to explain the development of the modified surface colours. Certain degree of surface amorphization was observed to be associated with the above N-ion implantation.
Sanil, D; Shetty, N J
2009-06-01
Anopheles stephensi, an important vector of malaria continues to be distributed widely in the Indian subcontinent. The natural vigour of the species combined with its new tolerance, indeed resistance to insecticides has made it obligatory that we look for control methods involving genetic manipulation. Hence, there is an immediate need for greater understanding of the genetics of this vector species. One of the requirements for such genetic studies is the establishment of naturally occurring mutants, establishment of the genetic basis for the same and use of such mutants in the genetic transformation studies and other genetic control programme(s). This paper describes the isolation and genetic studies of a larval colour mutant, green thorax (gt), and linkage studies involving another autosomal recessive mutant ruby- eye (ru) in An. stephensi. After the initial discovery, the mutant green thorax was crossed inter se and pure homozygous stock of the mutant was established. The stock of the mutant ruby- eye, which has been maintained as a pure stock in the laboratory. Crosses were made between the wild type and mutant, green thorax to determine the mode of inheritance of green thorax. For linkage studies, crosses were made between the mutant green thorax and another autosomal recessive mutant ruby-eye. The percentage cross-over was calculated for the genes linkage relationship for gt and gt ru. Results of crosses between mutant and wild type showed that the inheritance of green thorax (gt) in An. stephensi is monofactorial in nature. The gt allele is recessive to wild type and is autosomal. The linkage studies showed no linkage between ru and gt. The mutant gt represents an excellent marker for An. stephensi as it is expressed in late III instar stage of larvae and is prominent in IV instar and pupal stages with complete penetrance and high viability. The said mutant could be easily identified without the aid of a microscope. This mutant can be used extensively to
Application Of Pulsed Laser Holography To Nondestructive Testing Of Aircraft Structures
NASA Astrophysics Data System (ADS)
Fagot, Hubert; Smigielski, Paul; Arnaud, Jean-Louis
1983-03-01
Subsequently to laboratory tests, experiments were conducted on an aircraft undergoing maintenance in order to assess the possible uses of holographic interferometry for non-destructive testing of large aircraft structures. A double ruby laser was used delivering two pulses with a duration of 20 ns each. The two pulses are separated by an arbitrary time interval At which is determined as a function of both the amplitude and frequency of the surface displacement. Shocks of the order of 100 mJ cause the structure under investigation to vibrate, the time interval At thereby ranging from 10 to 100 ps for a delay of a few ms after shock initiation. The method used is relatively insensitive to environmental disturbances. Although the laser delivers pulses of light of less than 100 mJ in energy, it is possible to visualize a field of 0.5 x1 m. Some results will be reported which have been obtained at the lower surface of an aerofoil, on a wheel well and on an air-brake. Finally a brief review will be made on the improvements envisaged on both the laser and the recording method in order to obtain an operational system for holographic non-destructive testing.
ERIC Educational Resources Information Center
Ahlquist, Roberta, Ed.; Gorski, Paul C., Ed.; Montano, Theresa, Ed.
2011-01-01
Hyper-accountability, corporatization, deficit ideology, and Ruby Payne's preparation of teachers to comply with these and other atrocities are not merely markers of philosophical shifts in education. They are manifestations of a neoliberal remaking of public schooling into a private and corporate enterprise. Collectively, these trends are seen…
USDA-ARS?s Scientific Manuscript database
60% of the $109 million processed by the U.S. red raspberry industry is in northern Washington. In 2012, late summer disease symptoms were observed in many raspberry fields. These symptoms were initially attributed to Verticillium dahliae, but other soilborne pathogens (Phytophthora rubi, Pratylench...
Experimental and clinical standards, and evolution of lasers in neurosurgery.
Devaux, B C; Roux, F X
1996-01-01
From initial experiments of ruby, argon and CO2 lasers on the nervous system so far, dramatic progress was made in delivery systems technology as well as in knowledge of laser-tissue interaction effects and hazards through various animal experiments and clinical experience. Most surgical effects of laser light on neural tissue and the central nervous system (CNS) are thermal lesions. Haemostasis, cutting and vaporization depend on laser emission parameters--wavelength, fluence and mode--and on the exposed tissues optical and thermal properties--water and haemoglobin content, thermal conductivity and specific heat. CO2 and Nd-YAG lasers have today a large place in the neurosurgical armamentarium, while new laser sources such as high power diode lasers will have one in the near future. Current applications of these lasers derive from their respective characteristics, and include CNS tumour and vascular malformation surgery, and stereotactic neurosurgery. Intracranial, spinal cord and intra-orbital meningiomas are the best lesions for laser use for haemostasis, dissection and tissue vaporization. Resection of acoustic neuromas, pituitary tumours, spinal cord neuromas, intracerebral gliomas and metastases may also benefit from lasers as accurate, haemostatic, non-contact instruments which reduce surgical trauma to the brain and eloquent structures such as brain stem and cranial nerves. Coagulative lasers (1.06 microns and 1.32 microns Nd-YAG, argon, or diode laser) will find an application for arteriovenous malformations and cavernomas. Any fiberoptic-guided laser will find a use during stereotactic neurosurgical procedures, including image-guided resection of tumours and vascular malformations and endoscopic tumour resection and cysts or entry into a ventricle. Besides these routine applications of lasers, laser interstitial thermotherapy (LITT) and photodynamic therapy (PDT) of brain tumours are still in the experimental stage. The choice of a laser in a
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tabita, F. Robert
2008-12-04
During the past years of this project we have made progress relative to the two major goals of the proposal: (1) to study the biochemistry and regulation of the reductive TCA cycle of CO 2 fixation and (2) to probe the physiological role of a RubisCO-like protein (RLP). Both studies primarily employ the green sulfur bacterium Chlorobium tepidum as well as other photosynthetic bacteria including Rhodospirillum rubrum and Rhodopseudomonas palustris.
Characteristics of laser-induced shock wave injury to the inner ear of rats
NASA Astrophysics Data System (ADS)
Kurioka, Takaomi; Matsunobu, Takeshi; Niwa, Katsuki; Tamura, Atsushi; Kawauchi, Satoko; Satoh, Yasushi; Sato, Shunichi; Shiotani, Akihiro
2014-12-01
Recently, the number of blast injuries of the inner ear has increased in the general population. In blast-induced inner ear injury, a shock wave (SW) component in the blast wave is considered to play an important role in sensorineural hearing loss. However, the mechanisms by which an SW affects inner ear tissue remain largely unknown. We aimed to establish a new animal model for SW-induced inner ear injury by using laser-induced SWs (LISWs) on rats. The LISWs were generated by irradiating an elastic laser target with 694-nm nanosecond pulses of a ruby laser. After LISW application to the cochlea through bone conduction, auditory measurements revealed the presence of inner ear dysfunction, the extent of which depended on LISW overpressure. A significantly lower survival rate of hair cells and spiral ganglion neurons, as well as severe oxidative damage, were observed in the inner ear exposed to an LISW. Although considerable differences in the pressure characteristics exist between LISWs and SWs in real blast waves, the functional and morphological changes shown by the present LISW-based model were similar to those observed in real blast-induced injury. Thus, our animal model is expected to be useful for laboratory-based research of blast-induced inner ear injury.
Defect Detection on Carbon Fibre Reinforced Plastics (cfrp) with Laser Generated Lamb Waves
NASA Astrophysics Data System (ADS)
Focke, O.; Huke, P.; Hildebrandt, A.
2011-06-01
Standard ultrasound methods using a phased-array or a single transducer are commonly used for non-destructive evaluation (NDE) during manufacturing of carbon fiber reinforced plastics (CFRP) parts and certificated testing schemes were developed for individual parts and geometries. However, most testing methods need direct contact, matching gels and remain therefore time consuming. Laser-Ultrasonics is advantageous due to the contactless measurement technology and high accessibility even on complex parts. Despite the non-destructive testing with body waves, we show that the NDE can be expanded using two-dimensional surface (Lamb) waves for detection of delaminations close to the surface or small deteriorations caused by e.g. impacts. Lamb waves have been excited with a single transducer and with a short-pulse Laser with additionally producing A0-and S0-Lamb waves. The waves were detected with a shearography setup that allows for measuring two-dimensionally the displacement of a surface. Short integration times of the camera were realized using a pulsed ruby laser for illumination. As a consequence to the anisotropy the propagation in different directions exhibits individual characteristics like amplitude, damping and velocity. This has motivated to build up models for the propagation of Lamb waves and to compare them with experimental results.
Characteristics of laser-induced shock wave injury to the inner ear of rats.
Kurioka, Takaomi; Matsunobu, Takeshi; Niwa, Katsuki; Tamura, Atsushi; Kawauchi, Satoko; Satoh, Yasushi; Sato, Shunichi; Shiotani, Akihiro
2014-12-01
Recently, the number of blast injuries of the inner ear has increased in the general population. In blast-induced inner ear injury, a shock wave (SW) component in the blast wave is considered to play an important role in sensorineural hearing loss. However, the mechanisms by which an SW affects inner ear tissue remain largely unknown. We aimed to establish a new animal model for SW-induced inner ear injury by using laser-induced SWs (LISWs) on rats. The LISWs were generated by irradiating an elastic laser target with 694-nm nanosecond pulses of a ruby laser. After LISW application to the cochlea through bone conduction, auditory measurements revealed the presence of inner ear dysfunction, the extent of which depended on LISW overpressure. A significantly lower survival rate of hair cells and spiral ganglion neurons, as well as severe oxidative damage, were observed in the inner ear exposed to an LISW. Although considerable differences in the pressure characteristics exist between LISWs and SWs in real blast waves, the functional and morphological changes shown by the present LISW-based model were similar to those observed in real blast-induced injury. Thus, our animal model is expected to be useful for laboratory-based research of blast-induced inner ear injury.
Holographic Cinematography With The Help Of A Pulse YAG Laser
NASA Astrophysics Data System (ADS)
Smigielski, P.; Fagot, H.; Albe, F.
1985-02-01
For many years opticists have tried to achieve 3D-cinematography with the help of holography. The term "cineholography" has been introduced in 1965. At that time the method consisted in superimposing on the same photographic plate various holograms recorded at different times. The image separation was achieved by rotating either the plate in its plane or the reference beam during both the recording and reconstructing processes. The number of views was limited by the principle itself, but a high repetition rate (100 kHz) has been obtained with a pulsed ruby laser. Then other experiments have been conducted by different authors, mainly in the Soviet Unions and in the United States of America, by using the principle of classical cinematography in which the image separation is obtained by translating the film. With this method we have recorded the first French holographic movies on 35 mm Agfa films with the help of a pulsed YAG laser built in our laboratory. This frequency doubled laser (X = 0.532 pm) delivers pulses of 20 ns with an energy of 30 HO at a repetition rate of 24 Hz. The experimental arrangements are described and some images of diffuse moving objects are presented. The volume of the recording scene is greater than one cubic meter. The coherence length of the laser is higher than one meter and remains steady during the recording process. Results are discussed and an outlook on the future is given with special respect to high repetition rate techniques.
50 years LASERS: in vitro diagnostics, clinical applications and perspectives.
Spyropoulos, Basile
2011-01-01
1960 Theodore Maiman built the first Ruby-LASER, starting-point for half a century of R&D on Biomedical LASER continuous improvement. The purpose of this paper is to contribute a review of the often disregarded, however, extremely important Industrial Property documents of LASER-based in vitro Diagnostics devices. It is an attempt to sketch-out the patent-trail leading towards the modern Biomedical Laboratory and to offer an introduction to the employment of "exotic" systems, such as the Free Electron LASER (FEL), that are expected to focus on the fundamental processes of life, following chemical reactions and biological processes as they happen, on unprecedented time and size scales. There are various in vitro LASER applications, however, the most important ones include: Hybrid Coulter Principle-LASER Hematology Analyzers. Flow Cytometry systems. Fluorescent in situ Hybridization (FISH Techniques). Confocal LASER Scanning Microscopy and Cytometry. From the first fluorescence-based flow Cytometry device developed in 1968 by Wolfgang Göhde until nowadays, numerous improvements and new features related to these devices appeared. The relevant industrial property milestone-documents and their overall numeral trends are presented. In 1971, J. Madey invented and developed the Free Electron LASER (FEL), a vacuum-tube that uses a beam of relativistic electrons passing through a periodic, transverse magnetic field (wiggler) to produce coherent radiation, contained in an optical cavity defined by mirrors. A resonance condition that involves the energy of the electron beam, the strength of the magnetic field, and the periodicity of the magnet determines the wavelength of the radiation. The FEL Coherent Light Sources like the Linac Coherent Light Source (LCLS) at Stanford, CA, USA or the Xray Free Electron LASER (XFEL) at Hamburg, Germany, will work much like a high-speed (< 100 femtoseconds) camera, enabling scientists to take stop-motion pictures, on the nanoscale, of atoms
Beryl-bearing pegmatites in the Ruby Mountains and other areas in Nevada and northwestern Arizona
Olson, Jerry C.; Hinrichs, E. Neal
1960-01-01
Pegmatite occurs widely in Nevada and northwestern Arizona, but little mining has been done for such pegmatite minerals as mica, feldspar, beryl, and lepidolite. Reconnaissance for beryl-bearing pegmatite in Nevada and in part of Mohave County, Ariz., and detailed studies in the Dawley Canyon area, Elko County, Nev., have shown that beryl occurs in at least 11 districts in the region. Muscovite has been prospected or mined in the Ruby and Virgin Mountains, Nev., and in Mohave County, Ariz. Feldspar has been mined in the southern part of the region near Kingman, Ariz., and in Clark County, Nev. The pegmatites in the region range in age from Precambrian to late Mesozoic or Tertiary. Among the pegmatite minerals found or reported in the districts studied are beryl, chrysoberyl, scheelite, wolframite, garnet, tourmaline, fluorite, apatite, sphene, allanite, samarskite, euxenite, gadolinite, monazite, autunite, columbite-tantalite, lepidolite, molybdenite, and pyrite and other sulflde minerals. The principal beryl-bearing pegmatites examined are in the Oreana and Lakeview (Humboldt Canyon) areas, Pershing County; the Dawley Canyon area in the Ruby Mountains, Elko County, Nev.; and on the Hummingbird claims in the Virgin Mountains, Mohave County, Ariz. Beryl has also been reported in the Marietta district, Mineral County; the Sylvania district, Esmeralda County; near Crescent Peak and near Searchlight, Clark County, Nev.; and in the Painted Desert near Hoover Dam, Mohave County, Ariz. Pegmatites are abundant in the Ruby Mountains, chiefly north of the granite stock at Harrison Pass. In the Dawley Canyon area of 2.6 square miles at least 350 pegmatite dikes more than 1 foot thick were mapped, and beryl was found in small quantities in at least 100 of these dikes. Four of these dikes exceed 20 feet in thickness, and 1 is 55 feet thick. A few pegmatites were also examined in the Corral Creek, Gilbert Canyon, and Hankins Canyon areas in the Ruby Mountains.The pegmatite dikes
Slowing light down by low magnetic fields: pulse delay by transient spectral hole-burning in ruby.
Riesen, Hans; Rebane, Aleksander K; Szabo, Alex; Carceller, Ivana
2012-08-13
We report on the observation of slow light induced by transient spectral hole-burning in a solid, that is based on excited-state population storage. Experiments were conducted in the R1-line (2E←4A2 transition) of a 2.3 mm thick pink ruby (Al2O3:Cr(III) 130 ppm). Importantly, the pulse delay can be controlled by the application of a low external magnetic field B||c≤9 mT and delays of up to 11 ns with minimal pulse distortion are observed for ~55 ns Gaussian pulses. The delay corresponds to a group velocity value of ~c/1400. The experiment is very well modelled by linear spectral filter theory and the results indicate the possibility of using transient hole-burning based slow light experiments as a spectroscopic technique.
Photothermal and photochemical effects of laser light absorption by indocyanine green (ICG)
NASA Astrophysics Data System (ADS)
Yaseen, Mohammad A.; Diagaradjane, Parmeswaran; Pikkula, Brian M.; Yu, Jie; Wong, Michael S.; Anvari, Bahman
2005-04-01
Indocyanine Green (ICG) is clinically used as a fluorescent dye for imaging purposes. Its rapid circulation kinetics and minimal toxicity has prompted investigation into ICG's utility as a photosentitizer for therapeutic applications. Traditionally, optically mediated tumor therapy has focused on photodynamic therapy, which employs a photochemical mechanism resulting from the absorption of low intensity CW laser light by localized photosensitizers such as Photofrin II, Benzoporphyrin Derivative (BPD), ICG. Treatment of cutaneous vascular malformations such as port-wine stains, on the other hand, is based on a photothermal mechanism resulting from the absorption of high intensity pulsed laser light by hemoglobin. In this study, we compared the effectiveness of combining photochemical and photothermal mechanisms during application of ICG in conjunction with laser irradiation with the intention that the combined approach may lead to a reduction in the threshold dose of pulsed laser light required to treat hypervascular malformations. The blood vessels in rabbit ears were used as an in vivo model for targeted vasculature. Irradiation of the ears with IR light (λ=785 nm, Δτ = 3 min, Io = 120 mW) was used to elicit photochemical damage, while photothermal damage was brought about using pulses from a ruby laser (λ=694 nm, τ = 3 ms) with different fluences. For the combined modality, photochemical damage was induced first and followed by photothermal irradiation. This modality was compared with photothermal irradiation alone. The effectiveness of each irradiation scheme was assessed using histopathological analysis. We present preliminary data that suggests that pretreatment with photodynamic therapy before photothermal coagulation results in more severe vascular damage with lower photothermal fluence levels. The results of this study provide the foundation work for further exploration of the therapeutic potentials of photochemical and photothermal effects during
Mid-crustal flow during Tertiary extension in the Ruby Mountains core complex, Nevada
MacCready, T.; Snoke, A.W.; Wright, J.E.; Howard, K.A.
1997-01-01
Structural analysis and geochronologic data indicate a nearly orthogonal, late Eocene-Oligocene flow pattern in migmatitic infrastructure immediately beneath the kilometer-thick, extensional, mylonitic shear zone of the Ruby Mountains metamorphic core complex, Nevada. New U-Pb radiometric dating indicates that the development of a northward-trending lineation in the infrastructure is partly coeval with the development of a pervasive, west-northwest-trending lineation in the mylonitic shear zone. U-Pb monazite data from the leucogranite orthogneiss of Thorpe Creek indicate a crystallization age of ca. 36-39 Ma. Zircon fractions from a biotite monzogranite dike yield an age of ca. 29 Ma. The three dated samples from these units exhibit a penetrative, approximately north-south-trending elongation lineation. This lineation is commonly defined by oriented bundles of sillimanite and/or elongated aggregates of quartz and feldspar, indicating a synmetamorphic and syndeformational origin. The elongation lineation can be interpreted as a slip line in the flow plane of the migmatitic, nonmylonitic infrastructural core of the northern Ruby Mountains. A portion of this midcrustal flow is coeval with the well-documented, west-northwest sense of slip in the structurally overlying kilometer-thick, mid-Tertiary mylonitic shear zone. Lineations in the mylonitic zone are orthogonal to those in the deeper infrastructure, suggesting fundamental plastic decoupling between structural levels in this core complex. Furthermore, the infrastructure is characterized by overlapping, oppositely verging fold nappes, which are rooted to the east and west. One of the nappes may be synkinematic with the intrusion of the late Eocene orthogneiss of Thorpe Creek. In addition, the penetrative, elongation lineation in the infrastructure is subparallel to hinge lines of parasitic folds developed synchronous with the fold nappes, suggesting a kinematically related evolution. The area is evaluated in terms
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-18
... machinery heat 80223. exchangers and laser components. Euro Marble & Granite, Inc.... 4552 N. Ruby Street, 10/7/2010 The firm manufactures cut stone and stone Schiller Park, IL products such as countertops...
The development of laser surgery and medicine in China
NASA Astrophysics Data System (ADS)
Chen, Mingzhe
2005-07-01
The first Chinese ruby laser was created in 1961 and it was adopted for the retina coagulation experiment in 1965. Since 1970's, lasers had been widely applied clinically including the diseases suitable to physical therapy or acupuncture. The Chinese HpD was first produced in 1981 and first case of PDT was treated using Chinese HpD and Chinese lasers in the same year. Its success brought attention establishing a research group supported by the government in 1982. A nationwide systemic research project on PDT was then carried out. The step taken for PDT also accelerated the development of various fields of laser medicine and surgery. Laser treatments had been commonly adopted in the clinics and hospitals for the diseases of the superficial lesions and the lesions can be reached by the endoscopes non-invasively in 1980's. Since 1990's, the interventional laser therapies adopted mainly were percutaneous laser angioplasty, laser treatments through laparoscope, thoracoscope, arthroscope, neuro-endoscope etc. Ultrasound guided percutaneous laser heat coagulation for small hepatic cancer revealed good results and ultrasound guided percutaneous PDT for advanced large liver cancer revealed unexpected results after five years follow-up. At present: There are more long-term follow-up patients in the clinical trial; more advanced commercial available lasers and new techniques are adopted. Since the popularization of scanning electron microscope, laser scanning confocal microscope, laser induced auto-fluorescence system, high sensitivity fluorescence microscopic imaging system etc. in the laboratories, the basic studies can be more advanced and some times, the sub-cellular level can be reached; ultra-structure histo-morphology and gene studies are involved. In dermatology, Q-switched Alexandrite laser and other Q-switched lasers are used mainly for the treatment of skin pigmentation and vascular diseases; pulsed dye laser, ultra-pulsed CO2 laser are used in resurfacing, facial
Koral, C; Dell'Aglio, M; Gaudiuso, R; Alrifai, R; Torelli, M; De Giacomo, A
2018-05-15
In this paper, Nanoparticle-Enhanced Laser Induced Breakdown Spectroscopy is applied to transparent samples and gemstones with the aim to overcome the laser induced damage on the sample. We propose to deposit a layer of AuNPs on the sample surface by drying a colloidal solution before ablating the sample with a 532 nm pulsed laser beam. This procedure ensures that the most significant fraction of the beam, being in resonance with the AuNP surface plasmon, is mainly absorbed by the NP layer, which in turn results the breakdown to be induced on NPs rather than on the sample itself. The fast explosion of the NPs and the plasma induction allow the ablation and the transfer in the plasma phase of the portion of sample surface where the NPs were placed. The employed AuNPs are prepared in milliQ water without the use of any chemical stabilizers by Pulsed Laser Ablation in Liquids (PLAL), in order to obtain a strict control of composition and impurities, and to limit possible spectral interferences (except from Au emission lines). Therefore with this technique it is possible to obtain, together with the emission signal of Au (coming from atomized NPs), the emission spectrum of the sample, by limiting or avoiding the direct interaction of the laser pulse with the sample itself. This approach is extremely useful for the elemental analysis by laser ablation of high refractive index samples, where the laser pulse on an untreated surface can otherwise penetrate inside the sample, generate breakdown events below the superficial layer, and consequently cause cracks and other damage. The results obtained with NELIBS on high refractive index samples like glasses, tourmaline, aquamarine and ruby are very promising, and demonstrate the potentiality of this approach for precious gemstones analysis. Copyright © 2018 Elsevier B.V. All rights reserved.
An Inexpensive Fast-Light Detector for Student Laboratories
ERIC Educational Resources Information Center
Sanders, Steven G.; and others
1969-01-01
An optical dectector consisting of a high-speed PIN diode and a transistor was evaluated for use in student experiments with a pulsed-ruby laser. Pulses with 36-nsec risetimes were clearly resolved. (LC)
Response to Laser Treatment of Café au Lait Macules Based on Morphologic Features.
Belkin, Daniel A; Neckman, Julia P; Jeon, Hana; Friedman, Paul; Geronemus, Roy G
2017-11-01
Response to laser treatment for café au lait macules (CALMs) is inconsistent and difficult to predict. To test the hypothesis that irregularly bordered CALMs of the "coast of Maine" subtype respond better to treatment than those of the smooth-bordered "coast of California" subtype. This retrospective case series included patients from 2 multiple-clinician US practices treated from 2005 through 2016. All patients had a clinical diagnosis of CALM and were treated with a Q-switched or picosecond laser. A total of 51 consecutive patients were eligible, 6 of whom were excluded owing to ambiguous lesion subtype. Observers were blinded to final patient groupings. Treatment with 755-nm alexandrite picosecond laser, Q-switched ruby laser, Q-switched alexandrite laser, or Q-switched 1064-nm Nd:YAG laser. Main outcome was grade in a visual analog scale (VAS) consisting of 4 levels of treatment response: poor (grade 1, 0%-25% improvement), fair (grade 2, 26%-50% improvement), good (grade 3, 51%-75% improvement), and excellent (grade 4, 76%-100% improvement). Forty-five patients were included in the series, 19 with smooth-bordered lesions and 26 with irregularly bordered lesions. Thirty-four (76%) of the participants were female; 33 (73%) were white; and the mean age at the time of laser treatment was 14.5 years (range, 0-44 years). Smooth-bordered lesions received a mean VAS score of 1.76, corresponding to a fair response on average (26%-50% pigmentary clearance). Irregularly bordered lesions received a mean VAS score of 3.67, corresponding to an excellent response on average (76%-100% clearance) (P < .001). CALMs with jagged or ill-defined borders of the coast of Maine subtype tend to respond well to laser treatment, whereas those with smooth and well-defined borders of the coast of California subtype tend to have poor response. Clinicians using Q-switched or picosecond lasers to treat CALMs can use morphologic characteristics to help predict response and more
NASA Astrophysics Data System (ADS)
Champagnon, B.; Pilla, O.
1989-09-01
A correlation has been proposed by Urošević Panić Jovanić, Zeković and Savić between the lifetimes of Cr 3+ in various environments and the Dq parameter of ligand field theory. We show that these observed lifetimes depend on various factors such as multisite effects, reabsorption, thermal excitation or 2E 4T 2 mixing. The correlation between lifetimes and pressure on ruby has to consider these different effects.
Optical Diagnostic System For Observation Of Laser-Produced Shock Waves
NASA Astrophysics Data System (ADS)
Wilke, Mark D.; Stone, Sidney N.
1980-11-01
Several standard plasma and gas dynamic diagnostic techniques have been integrated into a system for observing the formation and propagation of high-power Nd:glass-laser generated one- and two-dimensional shockwaves in air from 0.1 torr to atmospheric pres-sures. Diagnostics include either single-frame, two-wavelength holographic ruby-laser interferometry or single-frame, single-wavelength interferometry with ten frames of shadow-graphy. Streaks or ten frames of the early luminous shocked region also are taken on all shots, as well as time-resolved luminosity measurements using high-speed biplanar vacuum photodiodes with various wavelength interference filters. Shadowgraphy frames are 200-ns long at 1-μs intervals, while emission frames are variable with a maximum 10-ns exposure and 50-ns interval. Both the streak mode and emission measurements with the vacuum diode allow subnanosecond time resolution. The interferometry provides 20-ns exposures from 500 ns to late times. Methods for reducing and interpreting the data have been, or are currently being, developed. Interactive computer programs for digitizing the fringe patterns provide fringe-shift profiles for Abel inversion. This has provided neutral gas and electron density information in the spherical, one-dimensional cases. Diagrams and photographs of the experiment will be shown as well as examples of the data that have been taken. Methods for data reduction will be outlined and some of the results shown.
Vali, Faisal; Hong, Robert
2007-10-11
With the evolution of AJAX, ruby on rails, advanced dynamic XHTML technologies and the advent of powerful user interface libraries for javascript (EXT, Yahoo User Interface Library), developers now have the ability to provide truly rich interfaces within web browsers, with reasonable effort and without third-party plugins. We designed and developed an example of such a solution. The User Interface allows radiation oncology practices to intuitively manage different dose fractionation schemes by helping estimate total dose to irradiated organs.
Bamel, Kiran; Gupta, Rajendra; Gupta, Shrish C
2015-11-01
Nicotine promotes rooting in leaf explants of tomato (Lycopersicon esculentum Miller var. Pusa Ruby). Nicotine at 10(-9) to 10(-3) M concentrations was added to the MS basal medium. The optimum response (three-fold increase in rooting) was obtained at 10(-7) M nicotine-enriched MS medium. At the same level i.e. 10(-7) M Nicotine induced dramatic increase (11-fold) in the number of secondary roots per root. We have shown earlier that exogenous acetylcholine induces a similar response in tomato leaves. Since nicotine is an agonist of one of the two acetylcholine receptors in animals, its ability to simulate ACh action in a plant system suggests the presence of the same molecular mechanism operative in both, animal and plant cells. Copyright © 2015 Elsevier B.V. All rights reserved.
USSR and Eastern Europe Scientific Abstracts, Physics and Mathematics, Number 34
1977-04-27
Russian abstract provided by the source] [Text] The relationship of duration and intensity of ultrashort pulses in a mode-locked ruby laser with Q...Excess charge carriers have been found to appear in pure Ge and Si crystals irradiated with short pulses from a C02 laser . The high purity and perfection...Illustrations 2; References 15: 8 Russian, 7 Western. USSR UDC 621.378.325 CONTROL OF DURATION OF ULTRASHORT PULSES IN MODE-LOCKED LASERS ZHURNAL
Fayne, Rachel A; Perper, Marina; Eber, Ariel E; Aldahan, Adam S; Nouri, Keyvan
2018-04-01
Unwanted facial and body hair presents as a common finding in many patients, such as females with hirsutism. With advances in laser and light technology, a clinically significant reduction in hair can be achieved in patients with light skin. However, in patients with darker skin, Fitzpatrick skin types (FST) IV-VI, the higher melanin content of the skin interferes with the proposed mechanism of laser-induced selective photothermolysis, which is to target the melanin in the hair follicle to cause permanent destruction of hair bulge stem cells. Many prospective and retrospective studies have been conducted with laser and light hair-removal devices, but most exclude patients with darkly pigmented skin, considering them a high-risk group for unwanted side effects, including pigmentation changes, blisters, and crust formation. We reviewed the published literature to obtain studies that focused on hair reduction for darker skin types. The existing literature for this patient population identifies longer wavelengths as a key element of the treatment protocol and indicates neodymium-doped yttrium aluminum garnet (Nd:YAG), diode, alexandrite, and ruby lasers as well as certain intense pulsed light sources for safe hair reduction with minimal side effects in patients with FST IV-VI, so long as energy settings and wavelengths are appropriate. Based on the findings in this review, safe and effective hair reduction for patients with FST IV-VI is achievable under proper treatment protocols and energy settings.
Starratt, Scott W.
2014-01-01
As paleolimnologists, we often look at the world through a 5-cm-diameter hole in the bottom of a lake, and although a number of studies have shown that a single core in the deepest part of a lake does not necessarily reflect the entire diatom flora, time and money often limit our ability to collect more than one core from a given site. This preliminary study is part of a multidisciplinary research project to understand Holocene climate variability in alpine regions of the Great Basin, and ultimately, to compare these high elevation records to the better studied pluvial records from adjacent valleys, in this case, the Ruby Valley.
Uranium plasma radiates in the UV spectrum
NASA Technical Reports Server (NTRS)
Williams, M. D.
1973-01-01
Description of an experiment designed to produce and spectroscopically analyze a simulated gas core reactor plasma in the spectral range from 300 to 1300 A. The plasma was produced by focusing the radiation of a Q-spoiled ruby laser onto the flat surface of a pure U-238 specimen.
NASA Astrophysics Data System (ADS)
Starratt, S.; Wahl, D.; Wan, E.; Anderson, L.; Wanket, J.; Olson, H.; Lloyd-Davies, T.; Kusler, J.
2009-12-01
Little is known about Holocene climate variability in north-central Nevada. This study aims to assess changes in watershed vegetation, fire history, lake levels and limnological conditions in order to understand secular to millennial-scale changes in regional climate. Favre Lake (2,899 m a.s.l.; 12 m deep; 7.7 hectares) is a flow-through lake in the northern Ruby Mountains. The primary sources of influent, both of which appear to be intermittent, are Castle Lake (2,989 m a.s.l.) and Liberty Lake (3,077 m a.s.l.). The bedrock of the three lake basins is early Paleozoic marble and Mesozoic granite and metamorphic rocks. Bathymetric maps and temperature, pH, salinity, and conductivity profiles have been generated for Favre Lake. Surface samples and a series of cores were also collected using a modified Livingstone piston corer. The presence of the Mazama ash in the basal sediment (~4 m below the sediment/water interface) indicates the record extends to ~7,700 cal yr B.P. Magnetic susceptibility (MS) and loss-on-ignition data indicate that the sediments in the lowest part of the core contain primary and reworked Mazama ash. About 2,000 years ago CaCO3 increased from 2 to 3% of the inorganic sediment. The upper 25 cm of the core are marked by an increase in MS which may indicate increased erosion due to grazing. Between about 7,700 and 6,000 cal yr B.P. the diatom flora is dominated by a diverse assemblage of benthic species. The remainder of the core is dominated by Fragilaria, suggesting that lake level rose and flooded the shelf that surrounds the depocenter of the lake. This is supported by changes in the abundance of the aquatic fern Isoetes. Pinus and Artemisia dominate the pollen record, followed by subordinate levels of Poaceae, Asteraceae, Amaranthaceae, and Sarcobatus. The late early Holocene (7,700-6,000 cal yr B.P.) is dominated by Pinus which is present in reduced amounts during the middle Holocene (6,000-3,000 cal yr B.P.) and then returns to dominance in
The chiral structure of porous chitin within the wing-scales of Callophrys rubi.
Schröder-Turk, G E; Wickham, S; Averdunk, H; Brink, F; Fitz Gerald, J D; Poladian, L; Large, M C J; Hyde, S T
2011-05-01
The structure of the porous three-dimensional reticulated pattern in the wing scales of the butterfly Callophrys rubi (the Green Hairstreak) is explored in detail, via scanning and transmission electron microscopy. A full 3D tomographic reconstruction of a section of this material reveals that the predominantly chitin material is assembled in the wing scale to form a structure whose geometry bears a remarkable correspondence to the srs net, well-known in solid state chemistry and soft materials science. The porous solid is bounded to an excellent approximation by a parallel surface to the Gyroid, a three-periodic minimal surface with cubic crystallographic symmetry I4₁32, as foreshadowed by Stavenga and Michielson. The scale of the structure is commensurate with the wavelength of visible light, with an edge of the conventional cubic unit cell of the parallel-Gyroid of approximately 310 nm. The genesis of this structure is discussed, and we suggest it affords a remarkable example of templating of a chiral material via soft matter, analogous to the formation of mesoporous silica via surfactant assemblies in solution. In the butterfly, the templating is achieved by the lipid-protein membranes within the smooth endoplasmic reticulum (while it remains in the chrysalis), that likely form cubic membranes, folded according to the form of the Gyroid. The subsequent formation of the chiral hard chitin framework is suggested to be driven by the gradual polymerisation of the chitin precursors, whose inherent chiral assembly in solution (during growth) promotes the formation of a single enantiomer. Copyright © 2011 Elsevier Inc. All rights reserved.
Coexistence of both gyroid chiralities in individual butterfly wing scales of Callophrys rubi.
Winter, Benjamin; Butz, Benjamin; Dieker, Christel; Schröder-Turk, Gerd E; Mecke, Klaus; Spiecker, Erdmann
2015-10-20
The wing scales of the Green Hairstreak butterfly Callophrys rubi consist of crystalline domains with sizes of a few micrometers, which exhibit a congenitally handed porous chitin microstructure identified as the chiral triply periodic single-gyroid structure. Here, the chirality and crystallographic texture of these domains are investigated by means of electron tomography. The tomograms unambiguously reveal the coexistence of the two enantiomeric forms of opposite handedness: the left- and right-handed gyroids. These two enantiomers appear with nonequal probabilities, implying that molecularly chiral constituents of the biological formation process presumably invoke a chiral symmetry break, resulting in a preferred enantiomeric form of the gyroid structure. Assuming validity of the formation model proposed by Ghiradella H (1989) J Morphol 202(1):69-88 and Saranathan V, et al. (2010) Proc Natl Acad Sci USA 107(26):11676-11681, where the two enantiomeric labyrinthine domains of the gyroid are connected to the extracellular and intra-SER spaces, our findings imply that the structural chirality of the single gyroid is, however, not caused by the molecular chirality of chitin. Furthermore, the wing scales are found to be highly textured, with a substantial fraction of domains exhibiting the <001> directions of the gyroid crystal aligned parallel to the scale surface normal. Both findings are needed to completely understand the photonic purpose of the single gyroid in gyroid-forming butterflies. More importantly, they show the level of control that morphogenesis exerts over secondary features of biological nanostructures, such as chirality or crystallographic texture, providing inspiration for biomimetic replication strategies for synthetic self-assembly mechanisms.
Hutchens, Thomas C; Darafsheh, Arash; Fardad, Amir; Antoszyk, Andrew N; Ying, Howard S; Astratov, Vasily N; Fried, Nathaniel M
2014-01-01
Vitreoretinal surgery is performed using mechanical dissection that sometimes results in iatrogenic complications, including vitreous hemorrhage, retinal breaks, incomplete membrane delamination, retinal distortion, microscopic damage, etc. An ultraprecise laser probe would be an ideal tool for cutting away pathologic membranes; however, the depth of surgery should be precisely controlled to protect the sensitive underlying retina. The ultraprecise surgical microprobe formed by chains of dielectric spheres for use with the erbium:YAG laser source (λ=2940 nm), with extremely short optical penetration depth in tissue, was optimized. Numerical modeling demonstrated a potential advantage of five-sphere focusing chains of sapphire spheres with index n=1.71 for ablating the tissue with self-limited depth around 10 to 20 μm. Novel detachable microsphere scalpel tips formed by chains of 300 μm sapphire (or ruby) spheres were tested on ophthalmic tissues, ex vivo. Detachable scalpel tips could allow for reusability of expensive mid-infrared trunk fibers between procedures, and offer more surgical customization by interchanging various scalpel tip configurations. An innovative method for aiming beam integration into the microsphere scalpel to improve the illumination of the surgical site was also shown. Single Er:YAG pulses of 0.2 mJ and 75-μs duration produced ablation craters in cornea epithelium for one, three, and five sphere structures with the latter generating the smallest crater depth (10 μm) with the least amount of thermal damage depth (30 μm). Detachable microsphere laser scalpel tips may allow surgeons better precision and safety compared to mechanical scalpels when operating on delicate or sensitive areas like the retina.
NASA Astrophysics Data System (ADS)
Achiwawanich, S.; James, B. D.; Liesegang, J.
2008-12-01
Surface effects on Mong Hsu rubies and Kanchanaburi sapphires after heat treatment in a controlled reducing atmosphere (5 mol% H 2/Ar) have been investigated using advanced surface science techniques including X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (ToF-SIMS). Visual appearance of the gemstones is clearly affected by the heat treatment in a reducing atmosphere. Kanchanaburi sapphires, in particular, exhibit Fe-containing precipitates after the heat treatment which have not been observed in previous studies under an inert atmosphere. Significant correlation between changes in visual appearance of the gemstones and variations in surface concentration of trace elements, especially Ti and Fe are observed. The XPS and ToF-SIMS results suggest that; (1) a reducing atmosphere affects the oxidation state of Fe; (2) dissociation of Fe-Ti interaction may occur during heat treatment.
Gorinstein, Shela; Leontowicz, Hanna; Leontowicz, Maria; Drzewiecki, Jerzy; Jastrzebski, Zenon; Tapia, María S; Katrich, Elena; Trakhtenberg, Simon
2005-09-23
Bioactive compounds of peels and peeled red Star Ruby (Sunrise) and blond qualities of Jaffa grapefruits were analyzed and their antioxidant potential was assessed. The dietary fibers were determined according to Prosky et al., the total polyphenol content by Folin-Ciocalteu method and measured at 765 nm, minerals and trace elements by atomic absorption spectrometer, phenolic and ascorbic acids by HPLC and the antioxidant potential by two different antioxidant assays (DPPH and beta-carotene linoleate model system). It was found that the contents of most studied bioactive compounds in both qualities are comparable. Only the contents of total polyphenols and flavonoids were higher in red grapefruits, but not significant. The antioxidant potentials of red peeled grapefruits and their peels were significantly higher than of blond peeled grapefruits and their peels (P<0.05 in both cases). Diets supplemented with peeled red and blond qualities of Jaffa grapefruits and their peels have increased the plasma antioxidant capacity and improved plasma lipid levels, especially in rats fed with cholesterol added diet. In conclusion, both qualities of Jaffa grapefruits contain high quantities of bioactive compounds, but the antioxidant potential of red grapefruits is significantly higher. Diets supplemented with both qualities of Jaffa grapefruits improve the plasma lipid levels and increase the plasma antioxidant activity, especially in rats fed with cholesterol added diets. Jaffa grapefruits, especially their red Star Ruby quality, could be a valuable supplementation for diseases-preventing diets.
Coexistence of both gyroid chiralities in individual butterfly wing scales of Callophrys rubi
Winter, Benjamin; Butz, Benjamin; Dieker, Christel; Schröder-Turk, Gerd E.; Mecke, Klaus; Spiecker, Erdmann
2015-01-01
The wing scales of the Green Hairstreak butterfly Callophrys rubi consist of crystalline domains with sizes of a few micrometers, which exhibit a congenitally handed porous chitin microstructure identified as the chiral triply periodic single-gyroid structure. Here, the chirality and crystallographic texture of these domains are investigated by means of electron tomography. The tomograms unambiguously reveal the coexistence of the two enantiomeric forms of opposite handedness: the left- and right-handed gyroids. These two enantiomers appear with nonequal probabilities, implying that molecularly chiral constituents of the biological formation process presumably invoke a chiral symmetry break, resulting in a preferred enantiomeric form of the gyroid structure. Assuming validity of the formation model proposed by Ghiradella H (1989) J Morphol 202(1):69–88 and Saranathan V, et al. (2010) Proc Natl Acad Sci USA 107(26):11676–11681, where the two enantiomeric labyrinthine domains of the gyroid are connected to the extracellular and intra-SER spaces, our findings imply that the structural chirality of the single gyroid is, however, not caused by the molecular chirality of chitin. Furthermore, the wing scales are found to be highly textured, with a substantial fraction of domains exhibiting the <001> directions of the gyroid crystal aligned parallel to the scale surface normal. Both findings are needed to completely understand the photonic purpose of the single gyroid in gyroid-forming butterflies. More importantly, they show the level of control that morphogenesis exerts over secondary features of biological nanostructures, such as chirality or crystallographic texture, providing inspiration for biomimetic replication strategies for synthetic self-assembly mechanisms. PMID:26438839
Intracavity brillouin scattering from passive Q-spoiling cells.
Wick, R V; Guenther, A H
1968-01-01
Stimulated Brillouin scattering from the methanol solvent used in conjunction with cryptocyanine bleachable dye in a ruby laser cavity has been observed at low megawatt output powers. The frequency shifts of the Brillouin scattered radiation produced within the laser cavity are slightly less than frequency shifts produced in an external methanol cell. The Brillouin radiation was eliminated even at output power levels in excess of 250 MW when a 3-mm length cell was used in place of the 25.4-mm commercial cell.
Pulse Width Dependence Of Pigment Cell Damage At 694 nm In Guinea Pig Skin
NASA Astrophysics Data System (ADS)
Dover, Jeffrey S.; Polla, Luigi L.; Margolis, Randall J.; Whitaker, Diana; Watanabe, Schinichi; Murphy, George F.; Parrish, John A.; Anderson, R. R.
1987-03-01
351 nm, 20-nsec XeF excimer laser irradiation has previously been shown to selectively target and damage melanosomes in human skin. In the following studies selective targeting with melanosomal photodisruption has been demonstrated in pigmented guinea pig skin with a Q-switched 40-nsec ruby laser, and a 750-nsec pulsed dye laser but not with a 400-usec pulsed dye laser. The pulse width dependence of melanosomal disruption, occurring only at pulsewidths shorter than the thermal relaxation time of the melanosome (0.5 - 1.0 usec), is in accordance with the theory of selective photothermolysis. Possible mechanisms of melanosomal photodisruption include development of sudden thermal gradients leading to cavitation or shock wave production.
Pulsed laser annealing of high-dose Ag+-ion implanted Si layer
NASA Astrophysics Data System (ADS)
Batalov, R. I.; Nuzhdin, V. I.; Valeev, V. F.; Vorobev, V. V.; Osin, Yu N.; Ivlev, G. D.; Stepanov, A. L.
2018-01-01
The formation of a crystalline composite Ag:Si material with Ag nanoparticles by low-energy (E = 30 keV) high-dose (D = 1.5 × 1017 ion cm-2) Ag+ implantation into a monocrystalline c-Si substrate followed by nanosecond pulsed laser annealing (PLA) is demonstrated. Compared to traditional thermal annealing, PLA allows us to perform local heating of the sample both for its depth and area, and eliminate implantation-induced defects more efficiently, due to rapid liquid-phase recrystallization. Moreover, dopant diffusion during a nanosecond laser pulse is mainly limited by the molten region, where the dopant diffusion coefficient is several orders of magnitude higher than in the solid state. During PLA by a ruby laser (λ = 0.694 µm), the optical probing of the irradiated zone at λ = 1.064 µm with registration of time-dependent reflectivity R(t) was carried out. By scanning electron microscopy, it was established that Ag+ implantation leads to the creation of a thin amorphous Ag:Si layer of porous structure, containing Ag nanoparticles with sizes of 10-30 nm. PLA with energy density W = 1.2-1.8 J cm-2 results in the melting of the implanted layer (d ~ 60 nm) and the topmost layers of the c-Si substrate (d < 400 nm), followed by the rapid recrystallization of the Si matrix containing Ag nanoparticles with dominate sizes of 5-15 nm and some fraction of larger particles of 40-60 nm. Energy dispersive x-ray (EDX) spectroscopy did not show a noticeable change of Ag atomic concentration in the implanted layer after PLA. Spectral dependence R(λ) of Ag:Si layers showed the partial recovery of c-Si bands with maxima at 275 and 365 nm with simultaneous weakening of plasmon band for Ag nanoparticles in Si at 835 nm.
Hilton, B.; Miller, M.W.
2003-01-01
We estimated annual apparent survival, recruitment, and rate of population growth of breeding Ruby-throated Hummingbirds (Archilochus colubris), while controlling for transients, by using 18 years of capture-mark-recapture data collected during 1984-2001 at Hilton Pond Center for Piedmont Natural History near York, South Carolina. Resident males had lower apparent survival (0.30 +/- 0.05 SE) than females (0.43 +/- 0.04). Estimates of apparent survival did not differ by age. Point estimates suggested that newly banded males were less likely than females to be residents, but standard errors of these estimates overlapped (males: 0.60 +/- 0.14 SE; females: 0.67 +/- 0.09). Estimated female recruitment was 0.60 +/- 0.06 SE, meaning that 60% of adult females present in any given year had entered the population during the previous year. Our estimate for rate of change indicated the population of female hummingbirds was stable during the study period (1.04 +/- 0.04 SE). We suggest an annual goal of greater than or equal to 64 adult females and greater than or equal to 64 immature females released per banding area to enable rigorous future tests for effects of covariates on population dynamics. Development of a broader cooperating network of hummingbird banders in eastern North America could allow tests for regional or metapopulation dynamics in this species.
Wannamaker, Philip E.; Doerner, William M.; Stodt, John A.; Sodergen, Timothy L.; Rodriguez, Brian D.
2002-01-01
We have collected about 150 magnetotelluric (MT) soundings in northeastern Nevada in the region of the Ruby Mountains metamorphic core complex uplift and southern Carlin mineral trend, in an effort to illuminate controls on core complex evolution and deposition of world-class gold deposits. The region has experienced a broad range of tectonic events including several periods of compressional and extensional deformation, which have contributed to the total expression of electrical resistivity. Most of the soundings are in three east-west profiles across increasing degrees of core uplift to the north (Bald Mountain, Harrison Pass and Secret Pass latitudes). Two shorter lines cross a prominent east-west structure to the north of the northern profile. MT impedance tensor and vertical magnetic field rotations imply a N-NNE average regional geoelectric strike, similar to surface geologic trends. Model resistivity cross sections were derived using a 2-D inversion algorithm, which damps departures of model parameters from an a priori structure, emphasizing the transverse magnetic (TM) mode and vertical magnetic field data. Geological interpretation of the resistivity combines previous seismic, potential field and isotope models, structural and petrological models for regional compression and extension, and detailed structural/stratigraphic interpretations incorporating drilling for petroleum and mineral exploration. To first order, the resistivity structure is one of a moderately conductive, Phanerozoic sedimentary section fundamentally disrupted by intrusion and uplift of resistive crystalline rocks. Late Devonian and early Mississippian shales of the Pilot and Chainman Formations together form an important conductive marker sequence in the stratigraphy and show pronounced increases in conductance (conductivity-thickness product) from east to west. These increases in conductance are attributed to graphitization caused by Elko-Sevier era compressional shear deformation and
Welch, Kenneth C.; Allalou, Amina; Sehgal, Prateek; Cheng, Jason; Ashok, Aarthi
2013-01-01
Glucose transporter (GLUT) proteins play a key role in the transport of monosaccharides across cellular membranes, and thus, blood sugar regulation and tissue metabolism. Patterns of GLUT expression, including the insulin-responsive GLUT4, have been well characterized in mammals. However, relatively little is known about patterns of GLUT expression in birds with existing data limited to the granivorous or herbivorous chicken, duck and sparrow. The smallest avian taxa, hummingbirds, exhibit some of the highest fasted and fed blood glucose levels and display an unusual ability to switch rapidly and completely between endogenous fat and exogenous sugar to fuel energetically expensive hovering flight. Despite this, nothing is known about the GLUT transporters that enable observed rapid rates of carbohydrate flux. We examined GLUT (GLUT1, 2, 3, & 4) expression in pectoralis, leg muscle, heart, liver, kidney, intestine and brain from both zebra finches (Taeniopygia guttata) and ruby-throated hummingbirds (Archilochus colubris). mRNA expression of all four transporters was probed using reverse-transcription PCR (RT-PCR). In addition, GLUT1 and 4 protein expression were assayed by western blot and immunostaining. Patterns of RNA and protein expression of GLUT1-3 in both species agree closely with published reports from other birds and mammals. As in other birds, and unlike in mammals, we did not detect GLUT4. A lack of GLUT4 correlates with hyperglycemia and an uncoupling of exercise intensity and relative oxidation of carbohydrates in hummingbirds. The function of GLUTs present in hummingbird muscle tissue (e.g. GLUT1 and 3) remain undescribed. Thus, further work is necessary to determine if high capillary density, and thus surface area across which cellular-mediated transport of sugars into active tissues (e.g. muscle) occurs, rather than taxon-specific differences in GLUT density or kinetics, can account for observed rapid rates of sugar flux into these tissues. PMID
Bamel, Kiran; Gupta, Rajendra; Gupta, Shirish C
2016-06-02
We present experimental evidence to show that acetylcholine (ACh) causes decrease in shoot formation in leaf explants of tomato (Lycopersicon esculentum Miller var Pusa Ruby) when cultured on shoot regeneration medium. The optimum response was obtained at 10(-4) M ACh-enriched medium. ACh also causes decrease in percentage of cultures forming callus and reduces the callus mass. Inhibitors of enzymatic hydrolysis of ACh, neostigmine and physostigmine, also suppresses callogenesis and caulogenesis. On the other hand, the breakdown products of Ach, choline and acetate, do not alter the morphogenic response induced on the shoot regeneration medium. Neostigmine showed optimal reduction in shoot formation at 10(-5) M. The explants cultured on neostigmine augmented medium showed decline in the activity of ACh hydrolyzing enzyme acetylcholinesterase. ACh and neostigmine added together showed marked reduction in callus mass. These results strongly support the role of ACh as a natural regulator of morphogenesis in tomato plants.
Bamel, Kiran; Gupta, Rajendra; Gupta, Shirish C.
2016-01-01
ABSTRACT We present experimental evidence to show that acetylcholine (ACh) causes decrease in shoot formation in leaf explants of tomato (Lycopersicon esculentum Miller var Pusa Ruby) when cultured on shoot regeneration medium. The optimum response was obtained at 10−4 M ACh-enriched medium. ACh also causes decrease in percentage of cultures forming callus and reduces the callus mass. Inhibitors of enzymatic hydrolysis of ACh, neostigmine and physostigmine, also suppresses callogenesis and caulogenesis. On the other hand, the breakdown products of Ach, choline and acetate, do not alter the morphogenic response induced on the shoot regeneration medium. Neostigmine showed optimal reduction in shoot formation at 10−5 M. The explants cultured on neostigmine augmented medium showed decline in the activity of ACh hydrolyzing enzyme acetylcholinesterase. ACh and neostigmine added together showed marked reduction in callus mass. These results strongly support the role of ACh as a natural regulator of morphogenesis in tomato plants. PMID:27348536
Wahl, David B.; Starratt, Scott W.; Anderson, Lysanna; Kusler, Jennifer E.; Fuller, Christopher C.; Addison, Jason A.; Wan, Elmira
2015-01-01
Multi-proxy analyses were conducted on a sediment core from Favre Lake, a high elevation cirque lake in the northern Ruby Mountains, Nevada, and provide a ca. 7600 year record of local and regional environmental change. Data indicate that lake levels were lower from 7600-5750 cal yr BP, when local climate was warmer and/or drier than today. Effective moisture increased after 5750 cal yr BP and remained relatively wet, and possibly cooler, until ca. 3750 cal yr BP. Results indicate generally dry conditions but also enhanced climatic variability from 3750-1750 cal yr BP, after which effective moisture increased. The timing of major changes in the Favre Lake proxy data are roughly coeval and in phase with those recorded in several paleoclimate studies across the Great Basin, suggesting regional climatic controls on local conditions and similar responses at high and low altitudes.
Laser Materials and Laser Spectroscopy - A Satellite Meeting of IQEC '88
NASA Astrophysics Data System (ADS)
Wang, Zhijiang; Zhang, Zhiming
1989-03-01
The Table of Contents for the book is as follows: * Laser Materials * Laser Site Spectroscopy of Transition Metal Ions in Glass * Spectroscopy of Chromium Doped Tunable Laser Materials * Spectroscopic Properties of Nd3+ Ions in LaMgAl11O19 Crystal * Spectral Study and 2.938 μm Laser Emission of Er3+ in the Y3Al5O12 Crystal * Raman-infrared Spectra and Radiationless Relaxation of Laser Crystal NdAl3(BO3)4 * A Study on HB and FLN in BaFCl0.5Br0.5:Sm2+ at 77K * Pair-pumped Upconversion Solid State Lasers * CW Upconversion Laser Action in Neodymium and Erbium doped Solids * Ultra-high Sensitive Upconversion Fluorescence of YbF3 Doped with Trace Tm3+ and Er3+ * The Growth and Properties of NYAB and EYAB Multifunctional Crystal * Study on Fluorescence and Laser Light of Er3+ in Glass * Growth and Properties of Single Crystal Fibers for Laser Materials * A Study on the Quality of Sapphire, Ruby and Ti3+ Doped Sapphire Grown by Temperature Gradient Technique (TGT) and Czochralski Technique (CZ) * The Measurement of Output Property of Ti3+ Al2O3 Laser Crystal * An Xα Study of the Laser Crystal MgF2 : V2+ * Q-switched NAB Laser * Miniature YAG Lasers * Study of High Efficiency {LiF}:{F}^-_2 Color Center Crystals * Study on the Formation Conditions and Optical Properties of (F2+)H Color Center in NaCl:OH- Crystals * Novel Spectroscopic Properties of {LiF}:{F}^+_3 - {F}_2 Mixed Color Centers Laser Crystals * Terraced Substrate Visible GaAlAs Semiconductor Lasers with a Large Optical Cavity * The Temperature Dependence of Gain Spectra, Threshold Current and Auger Recombination in InGaAsP-InP Double Heterojunction Laser diode * Time-resolved Photoluminescence and Energy Transfer of Bound Excitons in GaP:N Crystals * Optical Limiting with Semiconductors * A Critical Review of High-efficiency Crystals for Tunable Lasers * Parametric Scattering in β - BaB2O4 Crystal Induced by Picosecond Pulses * Generation of Picosecond Pulses at 193 nm by Frequency Mixing in β - BaB2O4
A peek into the history of sapphire crystal growth
NASA Astrophysics Data System (ADS)
Harris, Daniel C.
2003-09-01
After the chemical compositions of sapphire and ruby were unraveled in the middle of the 19th century, chemists set out to grow artificial crystals of these valuable gemstones. In 1885 a dealer in Geneva began to sell ruby that is now believed to have been created by flame fusion. Gemnologists rapidly concluded that the stones were artificial, but the Geneva ruby stimulated A. V. L. Verneuil in Paris to develop a flame fusion process to produce higher quality ruby and sapphire. By 1900 there was brisk demand for ruby manufactured by Verneuil's method, even though Verneuil did not publicly announce his work until 1902 and did not publish details until 1904. The Verneuil process was used with little alteration for the next 50 years. From 1932-1953, S. K. Popov in the Soviet Union established a capability for manufacturing high quality sapphire by the Verneuil process. In the U.S., under government contract, Linde Air Products Co. implemented the Verneuil process for ruby and sapphire when European sources were cut off during World War II. These materials were essential to the war effort for jewel bearings in precision instruments. In the 1960s and 1970s, the Czochralski process was implemented by Linde and its successor, Union Carbide, to make higher crystal quality material for ruby lasers. Stimulated by a government contract for structural fibers in 1966, H. LaBelle invented edge-defined film-fed growth (EFG). The Saphikon company, which is currently owned by Saint-Gobain, evolved from this effort. Independently and simultaneously, Stepanov developed edge-defined film-fed growth in the Soviet Union. In 1967 F. Schmid and D. Viechnicki at the Army Materials Research Lab grew sapphire by the heat exchanger method (HEM). Schmid went on to establish Crystal Systems, Inc. around this technology. Rotem Industries, founded in Israel in 1969, perfected the growth of sapphire hemispheres and near-net-shape domes by gradient solidification. In the U.S., growth of near
Pulsed Holographic Nondestructive Testing On Aircraft
NASA Astrophysics Data System (ADS)
Fagot, Hubert; Smigielski, Paul; Albe, Felix; Arnaud, Jean-Louis
1983-06-01
An holographic camera composed of two ruby lasers was built at ISL. It provides double exposure holograms with an adjustable time interval ranging from few ns to infinity. Various aircraft structures were first tested at ISL in laboratory conditions: honeycomb panels, wings ... The industrial tests on a military aircraft in maintenance checking were performed in a hangar of the SNIAS at Saint-Nazaire: wings, trap-door of the rear landing gear, air-brake... Electromechanical shocks were used to make the structure vibrate and to allow a fast trigger of the lasers. This avoids disturbance due to ambiant noises and vibrations.
Particle sizing in rocket motor studies utilizing hologram image processing
NASA Technical Reports Server (NTRS)
Netzer, David; Powers, John
1987-01-01
A technique of obtaining particle size information from holograms of combustion products is described. The holograms are obtained with a pulsed ruby laser through windows in a combustion chamber. The reconstruction is done with a krypton laser with the real image being viewed through a microscope. The particle size information is measured with a Quantimet 720 image processing system which can discriminate various features and perform measurements of the portions of interest in the image. Various problems that arise in the technique are discussed, especially those that are a consequence of the speckle due to the diffuse illumination used in the recording process.
Timing of the last glaciation and subsequent deglaciation in the Ruby Mountains, Great Basin, USA
NASA Astrophysics Data System (ADS)
Laabs, Benjamin J. C.; Munroe, Jeffrey S.; Best, Laura C.; Caffee, Marc W.
2013-01-01
The timing of the last Pleistocene glaciation in western North America is becoming increasingly well understood, largely due to improved methods of obtaining numerical ages of glacial deposits and landforms. Among these, cosmogenic radionuclide surface-exposure dating has been widely applied to moraines of mountain glaciers, providing the framework for understanding terrestrial climate change during and since the last glaciation in western North America. During the Late Pleistocene, the Great Basin of the western United States hosted numerous mountain glaciers, the deposits of which can provide valuable records of past climate changes if their ages can be precisely determined. In this study, twenty-nine cosmogenic radionuclide 10Be surface-exposure ages from a suite of moraines in Seitz Canyon, western Ruby Mountains, limit the timing of the last glacial episode in the interior Great Basin, known as the Angel Lake Glaciation. Results indicate that deposition of a terminal moraine and two recessional moraines began just prior to ˜20.5 ka and continued until ˜20.0 ka. Retreat from the next younger recessional moraine began at ˜17.2 ka, and final deglaciation began at ˜14.8 ka. These ages are broadly consistent with cosmogenic surface-exposure ages from the eastern Sierra Nevada and the western Wasatch Mountains, in the western and eastern extremes of the Great Basin respectively. Furthermore, these ages suggest that the valley glacier in Seitz Canyon was at or near its maximum extent before and during the hydrologic maxima of Pleistocene lakes in the Great Basin, supporting previous suggestions that a cool and wet climate persisted in this region during the early part of the last glacial-interglacial transition.
NASA Astrophysics Data System (ADS)
Patton, Wayne F.; Berggren, Kiera N.; Lopez, Mary F.
2001-04-01
Facilities engaged in proteome analysis differ significantly in the degree that they implement automated systems for high-throughput protein characterization. Though automated workstation environments are becoming more routine in the biotechnology and pharmaceutical sectors of industry, university-based laboratories often perform these tasks manually, submitting protein spots excised from polyacrylamide gels to institutional core facilities for identification. For broad compatibility with imaging platforms, an optimized fluorescent dye developed for proteomics applications should be designed taking into account that laser scanners use visible light excitation and that charge-coupled device camera systems and gas discharge transilluminators rely upon UV excitation. The luminescent ruthenium metal complex, SYPRO Ruby protein gel stain, is compatible with a variety of excitation sources since it displays intense UV (280 nm) and visible (470 nm) absorption maxima. Localization is achieved by noncovalent, electrostatic and hydrophobic binding of dye to proteins, with signal being detected at 610 nm. Since proteins are not covalently modified by the dye, compatibility with downstream microchemical characterization techniques such as matrix-assisted laser desorption/ionization-mass spectrometry is assured. Protocols have been devised for optimizing fluorophore intensity. SYPRO Ruby dye outperforms alternatives such as silver staining in terms of quantitative capabilities, compatibility with mass spectrometry and ease of integration into automated work environments.
Lado, Joanna; Rodrigo, María Jesús; Zacarías, Lorenzo
2015-10-01
Grapefruits are among the citrus species more sensitive to cold and develop chilling injury symptoms during prolonged postharvest storage at temperatures lower than 8 ℃-10 ℃. The plant hormone ethylene has been described either to protect or potentiate chilling injury development in citrus whereas little is known about transcriptional regulation of ethylene biosynthesis, perception and response during cold storage and how the hormone is regulating its own perception and signaling cascade. Then, the objective of the present study was to explore the transcriptional changes in the expression of ethylene biosynthesis, receptors and response genes during cold storage of the white Marsh and the red Star Ruby grapefruits. The effect of the ethylene action inhibitor, 1-MCP, was evaluated to investigate the involvement of ethylene in the regulation of the genes of its own biosynthesis and perception pathway. Ethylene production was very low at the harvest time in fruits of both varieties and experienced only minor changes during storage. By contrast, inhibition of ethylene perception by 1-MCP markedly induced ethylene production, and this increase was highly stimulated during shelf-life at 20 ℃, as well as transcription of ACS and ACO. These results support the auto-inhibitory regulation of ethylene in grapefruits, which acts mainly at the transcriptional level of ACS and ACO genes. Moreover, ethylene receptor1 and ethylene receptor3 were induced by cold while no clear role of ethylene was observed in the induction of ethylene receptors. However, ethylene appears to be implicated in the transcriptional regulation of ERFs both under cold storage and shelf-life. © The Author(s) 2014.
NASA Technical Reports Server (NTRS)
Yariv, A.
1972-01-01
A theoretical investigation revealed that a steady state mode-locked solution appropriate to ultrashort pulses is induced by Kerr liquids. An experimental investigation using a Q-switched ruby laser passively mode-locked by the insertion of a Kerr liquid verified the theory. Pulses of about 10 to the -11th power sec were generated when the relaxation time of the liquid was temperature tuned to approximately 10 to the -11th power sec.
1991-03-01
series of experiments have been performed to create a plane of light with a ruby pulse laser and photograph demonstrate the application of Particle...using a SIT 1. INTRODUCTION (silicon intensified tube) camera developed 6y Wernet at NASA Lewis (1989). Optical diagnostics have now become essential...lens for the PIV tests. Fig 2 shows a photograph of the As a result of this the potential sensitivity of the technique has nozzle guide vanes
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wrighton, Kelly C.; Castelle, Cindy J.; Varaljay, Vanessa A.
Metagenomic studies recently uncovered form II/III RubisCO genes, originally thought to only occur in archaea, from uncultivated bacteria of the candidate phyla radiation (CPR). There are no isolated CPR bacteria and these organisms are predicted to have limited metabolic capacities. Here we expand the known diversity of RubisCO from CPR lineages. We report a form of RubisCO, distantly similar to the archaeal form III RubisCO, in some CPR bacteria from the Parcubacteria (OD1), WS6 and Microgenomates (OP11) phyla. In addition, we significantly expand the Peregrinibacteria (PER) II/III RubisCO diversity and report the first II/III RubisCO sequences from the Microgenomates andmore » WS6 phyla. To provide a metabolic context for these RubisCOs, we reconstructed near-complete ( > 93%) PER genomes and the first closed genome for a WS6 bacterium, for which we propose the phylum name Dojkabacteria. Genomic and bioinformatic analyses suggest that the CPR RubisCOs function in a nucleoside pathway similar to that proposed in Archaea. Detection of form II/III RubisCO and nucleoside metabolism gene transcripts from a PER supports the operation of this pathway in situ. We demonstrate that the PER form II/III RubisCO is catalytically active, fixing CO 2 to physiologically complement phototrophic growth in a bacterial photoautotrophic RubisCO deletion strain. We propose that the identification of these RubisCOs across a radiation of obligately fermentative, small-celled organisms hints at a widespread, simple metabolic platform in which ribose may be a prominent currency.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ranson, W.A.; Garihan, J.M.; Ulmer, K.E.
1992-01-01
Amphibolite outcrops of unusual mineralogy within the Chunky Gal Mountain mafic-ultramafic complex display cm-scale rhythmic layers with moderate-steep dips. Layers are troctolitic, gabbroic, and anorthositic in composition, locally in contact with dunite of the Buck Creek ultramafic body. Meta-gabbroic layers contain striking bladed, emerald green amphibole as the chief mafic phase and relict bronzite with reacted margins. An additional major phase is plagioclase, [approximately]An 95 based on microprobe analysis. Ruby corundum is a minor (> 5%) constituent, which in some of the gabbroic rocks is mantled by a reaction rim of fibrolite. The clinoamphibole has optical properties resembling magnesio-cummingtonite: colorlessmore » to pale green in plane light with (+) sign and 2V = 60--70[degree]. However, microprobe analysis of the clinoamphibole indicates alumino-magnesio-hornblende. Although the texture of the bronzite shows that it is breaking down, it is clear that the clinoamphibole and corundum could not be the reaction products without the addition of Al, Ca, and Si in an aqueous fluid. Associated meta-troctolitic layers contain plagioclase and coarse, anhedral olivines displaying an inner corona of bladed orthopyroxene, rimmed by symplectite. The granulite facies reactions is: plagioclase + olivine = clinopyroxene + garnet. The mesoscopic-scale proximity of troctolitic and gabbroic rhythmic layers indicates both underwent granulite facies metamorphism. Retrogression to amphibolite grade is apparent only in the gabbroic layers, resulting in assemblages distinguished locally by abundant emerald green clinoamphibole and corundum porphyroblasts rimmed by fibrolite.« less
Innocenzi, P J; Hall, D R; Cross, J V
2001-06-01
The strawberry blossom weevil, Anthonomus rubi, is a major pest of strawberries in the United Kingdom and continental Europe. As part of a project to develop noninsecticidal control methods, the pheromone system of this species was investigated. Comparison of volatiles produced by field-collected, overwintering individuals of each sex led to identification of three male-specific compounds--(Z)-2-(3,3-dimethylcyclohexylidene)ethanol, (cis)-1-methyl-2-(1-methylethenyl)cyclobutaneethanol, and 2-(1-methylethenyl)-5-methyl-4-hexen-1-ol (lavandulol)--in amounts of 6.1, 1.2, and 0.82 microg/day/ male. The first two compounds are components of the aggregation pheromone of the boll weevil, Anthonomus grandis, grandlure II and grandlure I, respectively. Grandlure I was the (1R,2S)-(+) enantiomer and lavandulol was a single enantiomer, although the absolute configuration was not determined. Trace amounts of the other two grandlure components (Z)-(3,3-dimethylcyclohexylidene)acetaldehyde (grandlure III) and (E)-(3,3-dimethylcyclohexylidene)acetaldehyde (grandlure IV) were also detected. (E,E)-1-(1-Methylethyl)-4-methylene-8-methyl-2,7-cyclo-decadiene (germacrene-D), a known volatile from strawberry plants, Fragaria ananassa, was collected in increased amounts in the presence of pheromone-producing weevils. Male weevils only produced pheromone on F. ananassa and not on scented mayweed, Matracaria recutita, or cow parsley, Anthriscus sylvestris, although these are known food sources. In field trials using various combinations of synthetic grandlures I, II, III, and IV and lavandulol, significantly more weevils were caught in traps baited with blends containing grandlure I and II and lavandulol than in those baited with blends without lavandulol or unbaited controls. Addition of grandlure III and IV had no significant effect on attractiveness. Horizontal sticky traps were found to be more effective than vertical sticky traps or standard boll weevil traps. In mid-season females
Optical Spectroscopy Of Materials With Restricted Dimensions
NASA Astrophysics Data System (ADS)
Yen, William M...
1989-05-01
In this paper, we discuss various experimental advantages which are gained by using samples which have special dimensions and/or geometries. We limit our discussion here to the cylindrical geometry appropriate for optical fibers which are employed for various optoelectronic applications. We present results of laser spectroscopic studies of nominally pure and activated single crystal and glass fibers to illustrate some of these advantages. For example, we have succeeded for the first time in obtaining the dependence of the ruby R-lines and of the Raman spectra of sapphire on tensile stress. We further discuss a novel laser spectroscopic method, Dilution Narrowed Laser Spectroscopy or DNLS; we demonstrate this form of spectroscopy on single mode glass fibers activated with rare earth ions and consider the possibilities inherent in this technique.
A description of the lunar ranging station at McDonald Observatory.
NASA Technical Reports Server (NTRS)
Silverberg, E. C.; Currie, D. G.
1972-01-01
The equipment of this station which has been in operation since the deployment of the first corner reflector by the Apollo 11 astronauts. The McDonald 2.7-m telescope is used for both transmission and reception of pulsed ruby laser light during three 45-minute daily laser runs about three weeks in a month. The present laser pulse width, timing system, calibration procedures, and signal levels are designed to achieve ranging with an accuracy to 1 nanosecond. The data rates obtained since September, 1970, are consistent with the scientific commitments of the lunar ranging program. Most of the over 200 acquisitions obtained have an accuracy to better than plus or minus 30 cm. Details of the telescope matching optics, guiding and timing equipment, and calibration procedures are discussed. Representative lunar range data are included.
Different lasers and techniques for proliferative diabetic retinopathy.
Moutray, Tanya; Evans, Jennifer R; Lois, Noemi; Armstrong, David J; Peto, Tunde; Azuara-Blanco, Augusto
2018-03-15
Diabetic retinopathy (DR) is a chronic progressive disease of the retinal microvasculature associated with prolonged hyperglycaemia. Proliferative DR (PDR) is a sight-threatening complication of DR and is characterised by the development of abnormal new vessels in the retina, optic nerve head or anterior segment of the eye. Argon laser photocoagulation has been the gold standard for the treatment of PDR for many years, using regimens evaluated by the Early Treatment of Diabetic Retinopathy Study (ETDRS). Over the years, there have been modifications of the technique and introduction of new laser technologies. To assess the effects of different types of laser, other than argon laser, and different laser protocols, other than those established by the ETDRS, for the treatment of PDR. We compared different wavelengths; power and pulse duration; pattern, number and location of burns versus standard argon laser undertaken as specified by the ETDRS. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (which contains the Cochrane Eyes and Vision Trials Register) (2017, Issue 5); Ovid MEDLINE; Ovid Embase; LILACS; the ISRCTN registry; ClinicalTrials.gov and the ICTRP. The date of the search was 8 June 2017. We included randomised controlled trials (RCTs) of pan-retinal photocoagulation (PRP) using standard argon laser for treatment of PDR compared with any other laser modality. We excluded studies of lasers that are not in common use, such as the xenon arc, ruby or Krypton laser. We followed Cochrane guidelines and graded the certainty of evidence using the GRADE approach. We identified 11 studies from Europe (6), the USA (2), the Middle East (1) and Asia (2). Five studies compared different types of laser to argon: Nd:YAG (2 studies) or diode (3 studies). Other studies compared modifications to the standard argon laser PRP technique. The studies were poorly reported and we judged all to be at high risk of bias in at least one domain. The sample size
Metal silicides with energetic pulses
NASA Astrophysics Data System (ADS)
D'Anna, E.; Leggieri, G.; Luches, A.; Majni, G.; Nava, F.; Ottaviani, G.
1986-07-01
Samples formed of a thin metal film deposited on silicon single crystal were annealed with electron and laser (ruby and excimer) pulses over a wide range of fluences. From a comparison of the experimental results with the temperature profiles of the irradiated samples, it turns out that suicide formation starts when the metal/silicon interface reaches the lowest eutectic temperature of the binary metal/silicon system. The growth rate of reacted layers is of the order of 1 m/s.
Survey of Beamed Energy Propulsion Concepts by the MSFC Space Environmental Effects Team
NASA Technical Reports Server (NTRS)
Gray, P. A.; Nehls, M. K.; Edwards, D. L.; Carruth, M. R., Jr.; Munafo, Paul M. (Technical Monitor)
2002-01-01
This will be a survey paper of work that was performed by the Space Environmental Effects Team at NASA's Marshall Space Flight Center in the area of laser energy propulsion concepts. Two types of laser energy propulsion techniques were investigated. The first was ablative propulsion, which used a pulsed ruby laser impacting on single layer coatings and films. The purpose of this investigation was to determine the laser power density that produced an optimum coupling coefficient for each type of material tested. A commercial off-the-shelf multi-layer film was also investigated for possible applications in ablative micro-thrusters, and its optimum coupling coefficient was determined. The second type of study measured the purely photonic force provided by a 300W CW YAG laser. In initial studies, the photon force resulting from the momentum of incident photons was measured directly using a vacuum compatible microbalance and these results were compared to theory. Follow-on work used the same CW laser to excite a stable optical cavity for the purpose of amplifying the available force from incident photons.
Stimulated low-frequency Raman scattering in plant virus suspensions
NASA Astrophysics Data System (ADS)
Donchenko, E. K.; Karpova, O. V.; Kudryavtseva, A. D.; Pershin, S. M.; Savichev, V. I.; Strokov, M. A.; Tcherniega, N. V.; Zemskov, K. I.
2017-11-01
The study deals with laser pulse interaction with plant viruses: we investigated tobacco mosaic virus (TMV) and two types of potato viruses (PVX and PVA) in Tris-HCl pH7.5 buffer and in water. We used 20 ns ruby laser pulses for excitation. We employed Fabry-Pérot interferometers to record spectra of the light passing through the sample and reflected from it. For TMV and PVX in Tris-HCl pH7.5 buffer, same as for PVA in water, we observed additional spectral lines corresponding to the stimulated low-frequency Raman scattering (SLFRS). We believe we were the first to measure SLFRS frequency shifts, conversion efficiency and threshold. High conversion efficiency of the scattered light is evidence of laser pulses efficiently exciting gigahertz vibrations in viruses. SLFRS can be used to identify and affect biological nanoparticles.
Photographic laboratory studies of explosions.
NASA Technical Reports Server (NTRS)
Kamel, M. M.; Oppenheim, A. K.
1973-01-01
Description of a series of cinematographic studies of explosions made with a high-speed rotating-mirror streak camera which uses a high-frequency stroboscopic ruby laser as the light source. The results obtained mainly concern explosions initiated by focused laser irradiation from a pulsed neodymium laser in a detonating gas consisting essentially of an equimolar mixture of acetylene and oxygen at an initial pressure of 100 torr at room temperature. Among the most significant observations were observations of a spherical blast wave preceded by a Chapman-Jouguet detonation which is stabilized immediately after initiation, the merging of a spherical flame with a shock front of the blast wave in which the flame is propagating, the division of a spherical detonation front into a shock wave and flame, and the generation of shock waves by a network of spherical flames.
ERIC Educational Resources Information Center
Schewe, Phillip F.
1981-01-01
Examines the nature of laser light. Topics include: (1) production and characteristics of laser light; (2) nine types of lasers; (3) five laser techniques including holography; (4) laser spectroscopy; and (5) laser fusion and other applications. (SK)
2008-04-01
have genes that encode enzymes of the Calvin-Benson cycle, specifically for the key enzyme ribulose 1,5-bisphosphate carboxylase ( RubisCO ) which...Closer examination of the gene sequence annotated as RubisCO revealed that is more closely related to RubisCO -like (Hanson and Tabita 2001) proteins than...to RubisCO and is likely not involved in the Calvin-Benson cycle. Ionic Strength A recent paper (Müller, Walter et al. 2006) explored the
High efficiency laser-pumped emerald lasers
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lai, S.T.
1987-09-25
Highly efficient laser operation has been achieved in emerald. In a quasi-cw laser-pumped emerald laser, 64% output slope efficiency has been measured at 768 nm, corresponding to a laser quantum yield of 76%. An output power of 1.6 W was reached at 3.6 W of pump power at 647.1 nm from a krypton laser, and was pump power limited. The emerald laser has a tuning range of 720 to 842 nm. The round trip loss excluding the excited state absorption (ESA) is 0.4%/cm. These results indicate the high laser efficiency and the high optical quality of the emerald attainable inmore » the present laser.« less
UV lidar measurements of the stratospheric aerosol layer and comparison with other optical data
NASA Technical Reports Server (NTRS)
Uchino, O.
1985-01-01
After the violent volcanic eruptions of El Chichon in Mexico (17.33 deg. N, 93.20 deg. W) in late March and early April 1982, enhanced stratospheric aerosols have been monitored by ruby (lasing wavelength lambda=694.3 nm) or Nd:YAG lidars (lambda=1064 or 532 nm). By these lidars, visible or near-infrared optical informations of stratospheric aerosols and their space-time variations can be obtained. It is usually difficult to measure the background level of stratospheric aerosols by an ultraviolet (UV) lidar, since Rayleigh scattering prevails over Mie scattering in the stratosphere. However, after the large volcanic eruptions, UV lidar measurements of stratospheric aerosols are possible. In order to obtain UV optical properties of stratospheric aerosols, measurements have been made at Fukuoka (33.65 deg. N, 130.35 deg. E) by a p-terphenyl dye laser at a wavelength of 340.5 nm. Observational results during October 1982, through May 1983, are shown and are compared with the results obtained by a ruby lidar at Tsukuba (36.05 deg. N, 140.13 deg. E).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Collins, C.B.
1982-01-01
Progress in lasers is discussed. The subjects addressed include: excimer lasers, surface spectroscopy, modern laser spectroscopy, free electron lasers, cavities and propagation, lasers in medicine, X-ray and gamma ray lasers, laser spectroscopy of small molecules and clusters, optical bistability, excitons, nonlinear optics in the X-ray and gamma ray regions, collective atomic phenomena, tunable IR lasers, far IR/submillimeter lasers, and laser-assisted collisions. Also treated are: special applications, multiphoton processes in atoms and small molecules, nuclear pumped lasers, material processing and applications, polarization, high energy lasers, laser chemistry, IR molecular lasers, laser applications of collision and dissociation phenomena, solid state laser materials,more » phase conjugation, advances in laser technology for fusion, metal vapor lasers, picosecond phenomena, laser ranging and geodesy, and laser photochemistry of complex molecules.« less
Optical SETI: Moving Toward the Light
NASA Astrophysics Data System (ADS)
Ross, Monte; Kingsley, Stuart
In 2009, the SETI community celebrated a half-century since the classic paper by Giuseppe Cocconi and Philip Morrison in Nature, that described how we might look for radio transmissions from extraterrestrial civilizations. It is propitious that the publication of this book in 2010 marks both the 50th anniversary of Frank Drake's Project Ozma, and the 50th anniversary of the demonstration of the first (ruby) laser by Theodore Maiman. The invention of the laser was based on the maser work by Arthur Schawlow and Charles Townes and the simultaneous work of Gordon Gould. During this first half-century of SETI, most observing has been carried out in the radio spectrum, during which time there have been enormous developments in laser technology. Only during the past two decades has the optical approach to SETI, otherwise known as optical SETI, been given the attention it deserves.
Phased laser array for generating a powerful laser beam
Holzrichter, John F.; Ruggiero, Anthony J.
2004-02-17
A first injection laser signal and a first part of a reference laser beam are injected into a first laser element. At least one additional injection laser signal and at least one additional part of a reference laser beam are injected into at least one additional laser element. The first part of a reference laser beam and the at least one additional part of a reference laser beam are amplified and phase conjugated producing a first amplified output laser beam emanating from the first laser element and an additional amplified output laser beam emanating from the at least one additional laser element. The first amplified output laser beam and the additional amplified output laser beam are combined into a powerful laser beam.
Stimulated low-frequency Raman scattering in aqueous suspension of nanoparticles
NASA Astrophysics Data System (ADS)
Averyushkin, Anatolii S.; Baranov, Anatoly N.; Bulychev, Nikolay A.; Kazaryan, Mishik A.; Kudryavtseva, Anna D.; Shevchenko, Mikhail A.; Strokov, Maxim A.; Tcherniega, Nikolay V.; Zemskov, Konstantin I.
2018-04-01
The low-frequency acoustic mode in nanoparticles of different nature in aqueous suspension has been studied by stimulated low-frequency Raman scattering (SLFRS). Nanoparticles investigated (CuO, Ag, Au, ZnS) had different dimensions and different vibrational properties. Synthesis of cupric oxide nanoparticles in acoustoplasma discharge is described in details. SLFRS has been excited by nanosecond pulses of ruby laser. Spectra of the scattered light had been registered with the help of Fabry-Perot interferometer. SLFRS conversion efficiency, threshold and frequency shift of the scattered light are measured.
1994-04-01
Physics, Vol.72, No.12, 1992, pp.5535-5538. (12] Ragan, D.R., Gustavsen, R., and Schiferl , D., "Calibration of the Ruby R2 and R2 Fluorescence Shifts... Schiferl , D., "Pressure and Temperature Dependence of Laser-Induced Fluorescence of Sm:YAG to 100 kbar and 7000 C and an Empirical Model," Journal of...1964). IS. H. D’Amour. D. Schiferl , W. Denner, H. Schulz and 20. J. W. McCauley and G. V. Gibbs. Z. Knistallogr. 135, W, B. Holzapfel, J. appl. Phys. 49
Optical Production and Detection of Ultrasonic Waves in Metals for Nondestructive Testing
NASA Technical Reports Server (NTRS)
Morrison, R. A.
1972-01-01
Ultrasonic waves were produced by striking the surface of a metal with the focused one-joule pulse of a Q-switched ruby laser. Rayleigh (surface) waves and longitudinal waves were detected with conventional transducers. Optical methods of detection were tested and developed. Rayleigh waves were produced with an oscillator and transducer. They were optically detected on curved polished surfaces, and on unpolished surfaces. The technique uses a knife edge to detect small angle changes of the surface as the wave pulse passes the illuminated spot. Optical flaw detection using pulse echo and attenuation is demonstrated.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shand, M.L.; Lai, S.T.
1984-02-01
A CW laser-pumped emerald laser is reported. A 34 percent output power slope efficiency is observed with longitudinal pumping by a krypton laser in a nearly concentric cavity. The laser has been tuned from 728.8 to 809.0 nm. Losses in emerald are larger than those of alexandrite determined in a similar cavity. The present data also indicate that the excited state absorption minimum is shifted from that of alexandrite. 13 references.
New laser materials for laser diode pumping
NASA Technical Reports Server (NTRS)
Jenssen, H. P.
1990-01-01
The potential advantages of laser diode pumped solid state lasers are many with high overall efficiency being the most important. In order to realize these advantages, the solid state laser material needs to be optimized for diode laser pumping and for the particular application. In the case of the Nd laser, materials with a longer upper level radiative lifetime are desirable. This is because the laser diode is fundamentally a cw source, and to obtain high energy storage, a long integration time is necessary. Fluoride crystals are investigated as host materials for the Nd laser and also for IR laser transitions in other rare earths, such as the 2 micron Ho laser and the 3 micron Er laser. The approach is to investigate both known crystals, such as BaY2F8, as well as new crystals such as NaYF8. Emphasis is on the growth and spectroscopy of BaY2F8. These two efforts are parallel efforts. The growth effort is aimed at establishing conditions for obtaining large, high quality boules for laser samples. This requires numerous experimental growth runs; however, from these runs, samples suitable for spectroscopy become available.
Bajar, Bryce T.; Wang, Emily S.; Lam, Amy J.; Kim, Bongjae B.; Jacobs, Conor L.; Howe, Elizabeth S.; Davidson, Michael W.; Lin, Michael Z.; Chu, Jun
2016-01-01
Many genetically encoded biosensors use Förster resonance energy transfer (FRET) to dynamically report biomolecular activities. While pairs of cyan and yellow fluorescent proteins (FPs) are most commonly used as FRET partner fluorophores, respectively, green and red FPs offer distinct advantages for FRET, such as greater spectral separation, less phototoxicity, and lower autofluorescence. We previously developed the green-red FRET pair Clover and mRuby2, which improves responsiveness in intramolecular FRET reporters with different designs. Here we report the engineering of brighter and more photostable variants, mClover3 and mRuby3. mClover3 improves photostability by 60% and mRuby3 by 200% over the previous generation of fluorophores. Notably, mRuby3 is also 35% brighter than mRuby2, making it both the brightest and most photostable monomeric red FP yet characterized. Furthermore, we developed a standardized methodology for assessing FP performance in mammalian cells as stand-alone markers and as FRET partners. We found that mClover3 or mRuby3 expression in mammalian cells provides the highest fluorescence signals of all jellyfish GFP or coral RFP derivatives, respectively. Finally, using mClover3 and mRuby3, we engineered an improved version of the CaMKIIα reporter Camuiα with a larger response amplitude. PMID:26879144
Bajar, Bryce T; Wang, Emily S; Lam, Amy J; Kim, Bongjae B; Jacobs, Conor L; Howe, Elizabeth S; Davidson, Michael W; Lin, Michael Z; Chu, Jun
2016-02-16
Many genetically encoded biosensors use Förster resonance energy transfer (FRET) to dynamically report biomolecular activities. While pairs of cyan and yellow fluorescent proteins (FPs) are most commonly used as FRET partner fluorophores, respectively, green and red FPs offer distinct advantages for FRET, such as greater spectral separation, less phototoxicity, and lower autofluorescence. We previously developed the green-red FRET pair Clover and mRuby2, which improves responsiveness in intramolecular FRET reporters with different designs. Here we report the engineering of brighter and more photostable variants, mClover3 and mRuby3. mClover3 improves photostability by 60% and mRuby3 by 200% over the previous generation of fluorophores. Notably, mRuby3 is also 35% brighter than mRuby2, making it both the brightest and most photostable monomeric red FP yet characterized. Furthermore, we developed a standardized methodology for assessing FP performance in mammalian cells as stand-alone markers and as FRET partners. We found that mClover3 or mRuby3 expression in mammalian cells provides the highest fluorescence signals of all jellyfish GFP or coral RFP derivatives, respectively. Finally, using mClover3 and mRuby3, we engineered an improved version of the CaMKIIα reporter Camuiα with a larger response amplitude.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kertzscher, G; Beddar, S
Purpose: To study the promising potential of inorganic scintillator detectors (ISDs) and investigate various unwanted luminescence properties which may compromise their accuracy. Methods: The ISDs were comprised of a ruby crystal coupled to a polymethyl methacrylate (PMMA) fiber-optic cable and a charged coupled device camera. A new type of ISD was manufactured and included a long-pass filter that was sandwiched between the crystal and the fiber-optic cable. The purpose of the filter was to suppress the Cerenkov and fluorescence background light induced in the PMMA (the stem signal) from striking the ruby crystal, generating unwanted ruby excitation. A variety ofmore » experiments were performed to characterize the ruby based ISDs. The relative contribution of the induced ruby signal and the stem signal were quantified while exposing the detector and a bare fiber-optic cable to a high dose rate (HDR) brachytherapy (BT) source, respectively. The unwanted ruby excitation was quantified while irradiating the fiber-optic cable with the detector volume shielded. Other experiments addressed time-dependent luminescence properties and a comparison to other commonly used organic scintillator detectors (BCF-12, BCF-60). Results: When the BT source dwelled 0.5 cm away from the fiber-optic cable, the unwanted ruby excitation amounted to >5% of the total signal if the source-distance from the scintillator was >7 cm. However, the unwanted excitation was suppressed to <1% if the ISD incorporated an optic filter. The stem signal was suppressed with a 20 nm band-pass filter and was <3% as long as the source-distance was <7 cm. The ruby based ISDs generated signal up to 20(40) times that of BCF-12(BCF-60). Conclusion: The study presents solutions to unwanted luminescence properties of ruby based ISDs for HDR BT. An optic filter should be sandwiched between the scintillator volume and the fiber-optic cable to prevent the stem signal to excite the ruby crystal.« less
Laser system using ultra-short laser pulses
Dantus, Marcos [Okemos, MI; Lozovoy, Vadim V [Okemos, MI; Comstock, Matthew [Milford, MI
2009-10-27
A laser system using ultrashort laser pulses is provided. In another aspect of the present invention, the system includes a laser, pulse shaper and detection device. A further aspect of the present invention employs a femtosecond laser and binary pulse shaping (BPS). Still another aspect of the present invention uses a laser beam pulse, a pulse shaper and a SHG crystal.
Biological applications and effects of optical masers
NASA Astrophysics Data System (ADS)
Ham, William T., Jr.; Mueller, Harold A.; Williams, Ray C.; Geeraets, Walter J.; Ruffolo, John J., Jr.
1988-02-01
Research experiments and projects pertaining to the ocular hazards of lasers and other optical sources are reviewed and discussed in some detail. Early studies to determine threshold retinal damage in the rabbit from ruby and neodymium lasers are described and followed by more elaborate experiments with monkeys using the He;Ne laser. A comparison between threshold retinal lesions in human volunteers, monkeys and rabbits is given. Retinal damage in the rhesus monkey is evaluated in terms of visual acuity. Quantitative data on solar retinitis as determined in the rhesus monkey are provided and the effects of wavelength on light toxicity are evaluated for eight monochromatic laser lines. Experiments performed at Los Alamos to evaluate the ocular effects and hazards of picosecond and nanosecond pulses of radiation from CO2 and HF lasers are described. A list of published papers describing the above research is included. The HF laser effects on the rabbit cornea were very similar to those caused by exposure to the CO2 laser. The energy from the CO2 and HF lasers is completely absorbed in the superficial layers of the cornea, creating a sharp sonic or shock wave which can disrupt the epithelial cells but does not penetrate to the stroma.
Application of CO laser for laser balloon angioplasty
NASA Astrophysics Data System (ADS)
Miyamoto, Akira; Sakurada, Masami; Mizuno, Kyoichi; Kurita, Akira; Nakamura, Haruo; Suda, Akira; Arai, Tsunenori; Kikuchi, Makoto
1990-07-01
CO laser may be efficient for thermal fusion of intima of arterial wall without adventitial tissue damage because of high tissue absorption. To investigate the efficacy of CO laser as a laser bam for laser balloon angioplasty (LBA). CO laser was irradiated to aortic tissue through 3Oim polyethylene membrane and tissue temperature was measured by a thermistor. At 2Owatt/cm2 200joules/cm2 continuous laser exposure (CE), tissue temperature was above 100°C within a depth of 1mm and rapidly decreased to 60 °C or below between 2 and 3mm in depth. Moreover, adventitial temperature could be decreased by changing duty ratio (exposure duration/interval) of intermittent laser exposure (IE) despite of the same laser energy. Light microscopy showed high degree of medial coagulation necrosis in CE, however thermal coagulation was observed only at the surface of intima of aortic tissue in IE at duty ratio 1 / 2. These findings suggested CO laser could coagulate intimal layer with less deep thermal damage compared to Nd- YAG laser and that IE was better for superficial welding than CE at the same energy. We concluded that CO laser might be more efficient as a laser beam for LBA than Nd-YAG laser.
Laser Wakefield Acceleration Experiments Using HERCULES Laser
DOE Office of Scientific and Technical Information (OSTI.GOV)
Matsuoka, T.; McGuffey, C.; Dollar, F.
2009-07-25
Laser wakefield acceleration (LWFA) in a supersonic gas-jet using a self-guided laser pulse was studied by changing laser power and plasma electron density. The recently upgraded HERCULES laser facility equipped with wavefront correction enables a peak intensity of 6.1x10{sup 19} W/cm{sup 2} at laser power of 80 TW to be delivered to the gas-jet using F/10 focusing optics. We found that electron beam charge was increased significantly with an increase of laser power from 30 TW to 80 TW and showed density threshold behavior at a fixed laser power. We also studied the influence of laser focusing conditions by changingmore » the f-number of the optics to F/15 and found an increase in density threshold for electron production compared to the F/10 configuration. The analysis of different phenomena such as betatron motion of electrons, side scattering of the laser pulse for different focusing conditions, the influence of plasma density down ramp on LWFA are shown.« less
25 years of pulsed laser deposition
NASA Astrophysics Data System (ADS)
Lorenz, Michael; Ramachandra Rao, M. S.
2014-01-01
It is our pleasure to introduce this special issue appearing on the occasion of the 25th anniversary of pulsed laser deposition (PLD), which is today one of the most versatile growth techniques for oxide thin films and nanostructures. Ever since its invention, PLD has revolutionized the research on advanced functional oxides due to its ability to yield high-quality thin films, multilayers and heterostructures of a variety of multi-element material systems with rather simple technical means. We appreciate that the use of lasers to deposit films via ablation (now termed PLD) has been known since the 1960s after the invention of the first ruby laser. However, in the first two decades, PLD was something of a 'sleeping beauty' with only a few publications per year, as shown below. This state of hibernation ended abruptly with the advent of high T c superconductor research when scientists needed to grow high-quality thin films of multi-component high T c oxide systems. When most of the conventional growth techniques failed, the invention of PLD by T (Venky) Venkatesan clearly demonstrated that the newly discovered high-T c superconductor, YBa2Cu3O7-δ , could be stoichiometrically deposited as a high-quality nm-thin film with PLD [1]. As a remarkable highlight of this special issue, Venkatesan gives us his very personal reminiscence on these particularly innovative years of PLD beginning in 1986 [2]. After Venky's first paper [1], the importance of this invention was realized worldwide and the number of publications on PLD increased exponentially, as shown in figure 1. Figure 1. Figure 1. Published items per year with title or topic PLD. Data from Thomson Reuters Web of Knowledge in September 2013. After publication of Venky's famous paper in 1987 [1], the story of PLD's success began with a sudden jump in the number of publications, about 25 years ago. A first PLD textbook covering its basic understanding was soon published, in 1994, by Chrisey and Hubler [3]. Within a
Howard, Keith A.; Wooden, J.L.; Barnes, C.G.; Premo, W.R.; Snoke, A.W.; Lee, S.-Y.
2011-01-01
Gneissic pegmatitic leucogranite forms a dominant component (>600 km3) of the midcrustal infrastructure of the Ruby Mountains–East Humboldt Range core complex (Nevada, USA), and was assembled and modified episodically into a batholithic volume by myriad small intrusions from ca. 92 to 29 Ma. This injection complex consists of deformed sheets and other bodies emplaced syntectonically into a stratigraphic framework of marble, calc-silicate rocks, quartzite, schist, and other granitoids. Bodies of pegmatitic granite coalesce around host-rock remnants, which preserve relict or ghost stratigraphy, thrusts, and fold nappes. Intrusion inflated but did not disrupt the host-rock structure. The pegmatitic granite increases proportionally downward from structurally high positions to the bottoms of 1-km-deep canyons where it constitutes 95%–100% of the rock. Zircon and monazite dated by U-Pb (sensitive high-resolution ion microprobe, SHRIMP) for this rock type cluster diffusely at ages near 92, 82(?), 69, 38, and 29 Ma, and indicate successive or rejuvenated igneous crystallization multiple times over long periods of the Late Cretaceous and the Paleogene. Initial partial melting of unexposed pelites may have generated granite forerunners, which were remobilized several times in partial melting events. Sources for the pegmatitic granite differed isotopically from sources of similar-aged interleaved equigranular granites. Dominant Late Cretaceous and fewer Paleogene ages recorded from some pegmatitic granite samples, and Paleogene-only ages from the two structurally deepest samples, together with varying zircon trace element contents, suggest several disparate ages of final emplacement or remobilization of various small bodies. Folded sills that merge with dikes that cut the same folds suggest that there may have been in situ partial remobilization. The pegmatitic granite intrusions represent prolonged and recurrent generation, assembly, and partial melting modification of a
Frequency stabilization of diode-laser-pumped solid state lasers
NASA Technical Reports Server (NTRS)
Byer, Robert L.
1988-01-01
The goal of the NASA Sunlite program is to fly two diode-laser-pumped solid-state lasers on the space shuttle and while doing so to perform a measurement of their frequency stability and temporal coherence. These measurements will be made by combining the outputs of the two lasers on an optical radiation detector and spectrally analyzing the beat note. Diode-laser-pumped solid-state lasers have several characteristics that will make them useful in space borne experiments. First, this laser has high electrical efficiency. Second, it is of a technology that enables scaling to higher powers in the future. Third, the laser can be made extremely reliable, which is crucial for many space based applications. Fourth, they are frequency and amplitude stable and have high temporal coherence. Diode-laser-pumped solid-state lasers are inherently efficient. Recent results have shown 59 percent slope efficiency for a diode-laser-pumped solid-state laser. As for reliability, the laser proposed should be capable of continuous operation. This is possible because the diode lasers can be remote from the solid state gain medium by coupling through optical fibers. Diode lasers are constructed with optical detectors for monitoring their output power built into their mounting case. A computer can actively monitor the output of each diode laser. If it sees any variation in the output power that might indicate a problem, the computer can turn off that diode laser and turn on a backup diode laser. As for stability requirements, it is now generally believed that any laser can be stabilized if the laser has a frequency actuator capable of tuning the laser frequency as far as it is likely to drift in a measurement time.
Dual photon effects in nitrogen dioxide photolysis
NASA Technical Reports Server (NTRS)
Hakala, D.; Harteck, P.; Reeves, R. R.
1974-01-01
A previous study demonstrated two-photon consecutive absorption as being the most probable mechanism for the photodissociation of NO2 using a pulsed ruby laser at 6943 A. Additional data discussed here confirmed this and also examined an associated phenomenon, that of multiphoton induced fluorescence. The dissociation of NO2 by ON-O bond cleavage requires 3.4 eV, while the laser energy corresponds to 1.785 eV. The pooling of the energy of two photons would give more than enough energy to dissociate the NO2 into NO + O. Several mechanisms including (1) simultaneous absorption of two photons; (2) reaction of two singly excited NO2; (3) reaction of a singly excited NO2 with a ground state NO2; and (4) consecutive absorption of two photons were examined.
NASA Astrophysics Data System (ADS)
Dixit, S. K.
The field of gas lasers, started with the invention of He-Ne laser in 1961, has witnessed tremendous growth in terms of technology development, research into gaseous gain medium, resonator physics and application in widely diverse arenas. This was possible due to high versatility of gas lasers in terms of operating wavelengths, power, beam quality and mode of operation. In recent years, there is a definite trend to replace the gas lasers, wherever possible, by more efficient and compact solid-state lasers. However, for many industrial, medical and military applications, the gas lasers still rule the roost due to their high-power capabilities with good beam quality at specific wavelengths. This chapter presents a short review covering the operating principle, important technical details and application potential of all the important gas lasers such as He-Ne, CO2, argon ion, copper vapour, excimer and chemical lasers. These neutral atoms, ions and molecule gas lasers are discussed as per applicable electrical, chemical and optical excitation schemes. The optically pumped gas lasers, recently experiencing resurgence, are discussed in the context of far infrared THz molecular lasers, diode-pumped alkali lasers and optically pumped gas-filled hollow-core fibre lasers.
Bogdan Allemann, Inja; Kaufman, Joely
2011-01-01
Since the construction of the first laser in the 1960s, the role that lasers play in various medical specialities, including dermatology, has steadily increased. However, within the last 2 decades, the technological advances and the use of lasers in the field of dermatology have virtually exploded. Many treatments have only become possible with the use of lasers. Especially in aesthetic medicine, lasers are an essential tool in the treatment armamentarium. Due to better research and understanding of the physics of light and skin, there is now a wide and increasing array of different lasers and devices to choose from. The proper laser selection for each indication and treatment requires a profound understanding of laser physics and the basic laser principles. Understanding these principles will allow the laser operator to obtain better results and help avoid complications. This chapter will give an in-depth overview of the physical principles relevant in cutaneous laser surgery. Copyright © 2011 S. Karger AG, Basel.
Prototype laser-diode-pumped solid state laser transmitters
NASA Technical Reports Server (NTRS)
Kane, Thomas J.; Cheng, Emily A. P.; Wallace, Richard W.
1989-01-01
Monolithic, diode-pumped Nd:YAG ring lasers can provide diffraction-limited, single-frequency, narrow-linewidth, tunable output which is adequate for use as a local oscillator in a coherent communication system. A laser was built which had a linewidth of about 2 kHz, a power of 5 milliwatts, and which was tunable over a range of 30 MHz in a few microseconds. This laser was phase-locked to a second, similar laser. This demonstrates that the powerful technique of heterodyne detection is possible with a diode-pumped laser used as the local oscillator. Laser diode pumping of monolithic Nd:YAG rings can lead to output powers of hundreds of milliwatts from a single laser. A laser was built with a single-mode output of 310 mW. Several lasers can be chained together to sum their power, while maintaining diffraction-limited, single frequency operation. This technique was demonstrated with two lasers, with a total output of 340 mW, and is expected to be practical for up to about ten lasers. Thus with lasers of 310 mW, output of up to 3 W is possible. The chaining technique, if properly engineered, results in redundancy. The technique of resonant external modulation and doubling is designed to efficiently convert the continuous wave, infrared output of our lasers into low duty-cycle pulsed green output. This technique was verified through both computer modeling and experimentation. Further work would be necessary to develop a deliverable system using this technique.
Are Einstein's transition probabilities for spontaneous emission constant in plasmas?
NASA Technical Reports Server (NTRS)
Griem, H. R.; Huang, Y. W.; Wang, J.-S.; Moreno, J. C.
1991-01-01
An investigation is conducted with a ruby laser to experimentally confirm the quenching of spontaneous emission coefficients and propose a mechanism for the phenomenon. Results of previous experiments are examined to determine the consistency and validity of interpretations of the spontaneous emissions. For the C IV 3s-3p and 2s-3p transitions, the line-intensity ratios are found to be dependent on the separation of the laser from the target. Density gradients and Stark broadening are proposed to interpret the results in a way that does not invalidate the Einstein A values. The interpretation is extended to C III and N V, both of which demonstrate similar changes in A values in previous experiments. The apparent quenching of Ar II by photon collisions is explained by Rabi oscillations and power broadening in the argon-ion laser cavity. It is concluded that the changes in A values cannot result from dense plasma effects.
Zhou, H L; Hu, B; Zhang, C
2016-07-01
Melasma is a common acquired and distressing pigmentary disorder presenting to dermatology clinics. It is notably difficult to cure and has a tendency to relapse. The efficacy of classical Q-switched laser in treatment of melasma remains controversial. This study aims to investigate the efficacy and safety of 694-nm fractional QSRL combined with sonophoresis on levorotatory vitamin C for the treatment of melasma patients. Twenty-six patients with melasma were enrolled. Each patient received four to six fractional QSRL treatments at pulse energies of 2.5 to 4 J/cm(2) combined with sonophoresis on levorotatory vitamin C at 2-week intervals. The severity and the area of melasma were assessed by two investigators using the melasma area and severity index (MASI). Side effects were documented. Mean MASI score decreased from 15.51 ± 3.00 before treatment to 10.02 ± 4.39 3 months after the final treatment (P < 0.01). Side effects were few and transient. High-density coverage fractional QSRL combined with sonophoresis on levorotatory vitamin C is safe and effective for the treatment of melasma in Chinese patients.
Investigation of Laser Parameters in Silicon Pulsed Laser Conduction Welding
NASA Astrophysics Data System (ADS)
Shayganmanesh, Mahdi; Khoshnoud, Afsaneh
2016-03-01
In this paper, laser welding of silicon in conduction mode is investigated numerically. In this study, the effects of laser beam characteristics on the welding have been studied. In order to model the welding process, heat conduction equation is solved numerically and laser beam energy is considered as a boundary condition. Time depended heat conduction equation is used in our calculations to model pulsed laser welding. Thermo-physical and optical properties of the material are considered to be temperature dependent in our calculations. Effects of spatial and temporal laser beam parameters such as laser beam spot size, laser beam quality, laser beam polarization, laser incident angle, laser pulse energy, laser pulse width, pulse repetition frequency and welding speed on the welding characteristics are assessed. The results show that how the temperature dependent thermo-physical and optical parameters of the material are important in laser welding modeling. Also the results show how the parameters of the laser beam influence the welding characteristics.
Scott, Jill R [Idaho Falls, ID; Tremblay, Paul L [Idaho Falls, ID
2007-07-10
A laser device includes a target position, an optical component separated a distance J from the target position, and a laser energy source separated a distance H from the optical component, distance H being greater than distance J. A laser source manipulation mechanism exhibits a mechanical resolution of positioning the laser source. The mechanical resolution is less than a spatial resolution of laser energy at the target position as directed through the optical component. A vertical and a lateral index that intersect at an origin can be defined for the optical component. The manipulation mechanism can auto align laser aim through the origin during laser source motion. The laser source manipulation mechanism can include a mechanical index. The mechanical index can include a pivot point for laser source lateral motion and a reference point for laser source vertical motion. The target position can be located within an adverse environment including at least one of a high magnetic field, a vacuum system, a high pressure system, and a hazardous zone. The laser source and an electro-mechanical part of the manipulation mechanism can be located outside the adverse environment. The manipulation mechanism can include a Peaucellier linkage.
Scott, Jill R.; Tremblay, Paul L.
2004-11-23
A laser device includes a target position, an optical component separated a distance J from the target position, and a laser energy source separated a distance H from the optical component, distance H being greater than distance J. A laser source manipulation mechanism exhibits a mechanical resolution of positioning the laser source. The mechanical resolution is less than a spatial resolution of laser energy at the target position as directed through the optical component. A vertical and a lateral index that intersect at an origin can be defined for the optical component. The manipulation mechanism can auto align laser aim through the origin during laser source motion. The laser source manipulation mechanism can include a mechanical index. The mechanical index can include a pivot point for laser source lateral motion and a reference point for laser source vertical motion. The target position can be located within an adverse environment including at least one of a high magnetic field, a vacuum system, a high pressure system, and a hazardous zone. The laser source and an electro-mechanical part of the manipulation mechanism can be located outside the adverse environment. The manipulation mechanism can include a Peaucellier linkage.
Meesters, Arne A; Nieboer, Marilin J; Kezic, Sanja; de Rie, Menno A; Wolkerstorfer, Albert
2018-05-07
Efficacy of topical anesthetics can be enhanced by pretreatment of the skin with ablative fractional lasers. However, little is known about the role of parameters such as laser modality and laser density settings in this technique. Aims of this study were to compare the efficacy of pretreatment with two different ablative fractional laser modalities, a CO 2 laser and an Er:YAG laser, and to assess the role of laser density in ablative fractional laser assisted topical anesthesia. In each of 15 healthy subjects, four 10 × 10 mm test regions on the back were randomized to pretreatment (70-75 μm ablation depth) with CO 2 laser at 5% density, CO 2 laser at 15% density, Er:YAG laser at 5% density or Er:YAG laser at 15% density. Articaine hydrochloride 40 mg/ml + epinephrine 10 μg/ml solution was applied under occlusion to all four test regions. After 15 minutes, a pass with the CO 2 laser (1,500 μm ablation depth) was administered as pain stimulus to each test region. A reference pain stimulus was given on unanesthetized skin. The main outcome parameter, pain, was scored on a 0-10 visual analogue scale (VAS) after each pain stimulus. Median VAS scores were 1.50 [CO 2 5%], 0.50 [CO 2 15%], 1.50 [Er:YAG 5%], 0.43 [Er:YAG 15%], and 4.50 [unanesthetized reference]. VAS scores for all pretreated test regions were significantly lower compared to the untreated reference region (P < 0.01). We found no significant difference in VAS scores between the CO 2 and the Er:YAG laser pretreated regions. However, VAS scores were significantly lower at 15% density compared to 5% density for both for the CO 2 laser (P < 0.05) and the Er:YAG laser (P < 0.01). Pretreatment with the CO 2 laser was considered slightly more painful than pretreatment with Er:YAG laser by the subjects. Fractional laser assisted topical anesthesia is effective even with very low energy settings and an occlusion time of only 15 minutes. Both the CO 2 laser and the Er:YAG laser can
Veligdan, James T.
2000-11-14
A microphone for detecting sound pressure waves includes a laser resonator having a laser gain material aligned coaxially between a pair of first and second mirrors for producing a laser beam. A reference cell is disposed between the laser material and one of the mirrors for transmitting a reference portion of the laser beam between the mirrors. A sensing cell is disposed between the laser material and one of the mirrors, and is laterally displaced from the reference cell for transmitting a signal portion of the laser beam, with the sensing cell being open for receiving the sound waves. A photodetector is disposed in optical communication with the first mirror for receiving the laser beam, and produces an acoustic signal therefrom for the sound waves.
Biology of Symbioses between Marine Invertebrates and Intracellular Bacteria
1990-01-30
bisphosphate carboxylase We designed from published sequence information oligonucleotide primers which are complementary to conserved regions on RubisCO ...large and small subunit genes. These primers were used successfully to amplify using polymerase chain reaction (PCR) specific regions of RubisCO ...for the large subunit of ribulose bisphosphate carboxylase/oxygenase ( RubisCO ) to symbiont DNA shows that the symbionts from both deep-sea and shallow
Early, James W.; Lester, Charles S.
2004-01-13
Sequenced pulses of light from an excitation laser with at least two resonator cavities with separate output couplers are directed through a light modulator and a first polarzing analyzer. A portion of the light not rejected by the first polarizing analyzer is transported through a first optical fiber into a first ignitor laser rod in an ignitor laser. Another portion of the light is rejected by the first polarizing analyzer and directed through a halfwave plate into a second polarization analyzer. A first portion of the output of the second polarization analyzer passes through the second polarization analyzer to a second, oscillator, laser rod in the ignitor laser. A second portion of the output of the second polarization analyzer is redirected by the second polarization analyzer to a second optical fiber which delays the beam before the beam is combined with output of the first ignitor laser rod. Output of the second laser rod in the ignitor laser is directed into the first ignitor laser rod which was energized by light passing through the first polarizing analyzer. Combined output of the first ignitor laser rod and output of the second optical fiber is focused into a combustible fuel where the first short duration, high peak power pulse from the ignitor laser ignites the fuel and the second long duration, low peak power pulse directly from the excitation laser sustains the combustion.
Safe laser application requires more than laser safety
NASA Astrophysics Data System (ADS)
Frevel, A.; Steffensen, B.; Vassie, L.
1995-02-01
An overview is presented concerning aspects of laser safety in European industrial laser use. Surveys indicate that there is a large variation in the safety strategies amongst industrial laser users. Some key problem areas are highlighted. Emission of hazardous substances is a major problem for users of laser material processing systems where the majority of the particulate is of a sub-micrometre size, presenting a respiratory hazard. Studies show that in many cases emissions are not frequently monitored in factories and uncertainty exists over the hazards. Operators of laser machines do not receive adequate job training or safety training. The problem is compounded by a plethora of regulations and standards which are difficult to interpret and implement, and inspectors who are not conversant with the technology or the issues. A case is demonstrated for a more integrated approach to laser safety, taking into account the development of laser applications, organizational and personnel development, in addition to environmental and occupational health and safety aspects. It is necessary to achieve a harmonization between these elements in any organization involved in laser technology. This might be achieved through establishing technology transfer centres in laser technology.
Laser Safety: A Laser Alignment Practical Training Course
DOE Office of Scientific and Technical Information (OSTI.GOV)
Woods, Michael; Edstrom, Steve; /SLAC
2011-01-26
SLAC National Accelerator Laboratory has developed a Laser Alignment Practical Training Course as one of its core laser safety classes. The course is taught to small groups of up to three students and takes 1-3 hours to complete. This practical course is not a substitute for site-specific On-the-Job Training; it does, however, provide a good introduction in core laser safety practices that can be broadly applied. Alignment and diagnostic tasks are performed with low power lasers. Students learn safe alignment and diagnostic techniques and how to avoid common mistakes that might lead to an accident. The class is taught bymore » laser supervisors, enabling them to assess the skill level of new laser personnel and determine the subsequent level of supervision needed. The course has six alignment tasks. For each task, discussion points are given for the instructor to review with the students. The optics setup includes different wavelength lasers, a beam expander, mirrors, irises, a periscope, a beam-splitting polarizer and a diffraction grating. Diagnostic tools include viewing cards, an IR viewer and a ccd camera. Laser eyewear is available to block some laser wavelengths in the setup.« less
Lasers and laser-like devices: part one.
Stewart, Nicholas; Lim, Adrian C; Lowe, Patricia M; Goodman, Greg
2013-08-01
Lasers have been used in dermatology for nearly 50 years. Through their selective targeting of skin chromophores they have become the preferred treatment for many skin conditions, including vascular malformations, photorejuvenation and acne scars. The technology and design of lasers continue to evolve, allowing greater control of laser parameters and resulting in increased safety and efficacy for patients. Innovations have allowed the range of conditions and the skin types amenable to treatment, in both general and cosmetic dermatology, to expand over the last decade. Integrated skin cooling and laser beam fractionation, for example, have improved safety, patient tolerance and decreased downtime. Furthermore, the availability and affordability of quality devices continues to increase, allowing clinicians not only to access laser therapies more readily but also to develop their personal experience in this field. As a result, most Australian dermatologists now have access to laser therapies, either in their own practice or within referable proximity, and practical knowledge of these technologies is increasingly required and expected by patients. Non-laser energy devices utilising intense pulsed light, plasma, radiofrequency, ultrasound and cryolipolysis contribute to the modern laser practitioners' armamentarium and will also be discussed. © 2013 The Authors. Australasian Journal of Dermatology © 2013 The Australasian College of Dermatologists.
Laser surgery: using the carbon dioxide laser.
Wright, V. C.
1982-01-01
In 1917 Einstein theorized tha through an atomic process a unique kind of electromagnetic radiation could be produced by stimulated emission. When such radiation is in the optical or infrared spectrum it is termed laser (light amplification by stimulated emission of radiation) light. A laser, a high-intensity light source, emits a nearly parallel electromagnetic beam of energy at a given wavelength that can be captured by a lens and concentrated in the focal spot. The wavelength determines how the laser will be used. The carbon dioxide laser is now successfully employed for some surgical procedures in gynecology, otorhinolaryngology, neurosurgery, and plastic and general surgery. The CO2 laser beam is directed through the viewing system of an operating microscope or through a hand-held laser component. Its basic action in tissue is thermal vaporization; it causes minimal damage to adjacent tissues. Surgeons require special training in the basic methods and techniques of laser surgery, as well as in the safety standards that must be observed. Images FIG. 5 PMID:7074503
Early, James W.; Lester, Charles S.
2003-01-01
In the apparatus of the invention, a first excitation laser or other excitation light source is used in tandem with an ignitor laser to provide a compact, durable, engine deployable fuel ignition laser system. Reliable fuel ignition is provided over a wide range of fuel conditions by using a single remote excitation light source for one or more small lasers located proximate to one or more fuel combustion zones. In a third embodiment, alternating short and long pulses of light from the excitation light source are directed into the ignitor laser. Each of the embodiments of the invention can be multiplexed so as to provide laser light energy sequentially to more than one ignitor laser.
Transurethral vaporesection of prostate: diode laser or thulium laser?
Tan, Xinji; Zhang, Xiaobo; Li, Dongjie; Chen, Xiong; Dai, Yuanqing; Gu, Jie; Chen, Mingquan; Hu, Sheng; Bai, Yao; Ning, Yu
2018-05-01
This study compared the safety and effectiveness of the diode laser and thulium laser during prostate transurethral vaporesection for treating benign prostate hyperplasia (BPH). We retrospectively analyzed 205 patients with BPH who underwent a diode laser or thulium laser technique for prostate transurethral vaporesection from June 2016 to June 2017 and who were followed up for 3 months. Baseline characteristics of the patients, perioperative data, postoperative outcomes, and complications were compared. We also assessed the International Prostate Symptom Score (IPSS), quality of life (QoL), maximum flow rate (Q max ), average flow rate (AFR), and postvoid residual volume (PVR) at 1 and 3 months postoperatively to evaluate the functional improvement of each group. There were no significant differences between the diode laser and thulium laser groups related to age, prostate volume, operative time, postoperative hospital stays, hospitalization costs, or perioperative data. The catheterization time was 3.5 ± 0.8 days for the diode laser group and 4.7 ± 1.8 days for the thulium laser group (p < 0.05). Each group had dramatic improvements in IPSS, QoL, Q max , AFR, and PVR compared with the preoperative values (p < 0.05), although there were no significant differences between the two groups. Use of both diode laser and thulium laser contributes to safe, effective transurethral vaporesection in patients with symptomatic BPH. Diode laser, however, is better than thulium laser for prostate transurethral vaporesection because of its shorter catheterization time. The choice of surgical approach is more important than the choice of laser types during clinical decision making for transurethral laser prostatectomy.
Laser safety considerations for a mobile laser program
NASA Astrophysics Data System (ADS)
Flor, Mary
1997-05-01
An increased demand for advanced laser technology, especially in the area of cutaneous and cosmetic procedures has prompted physicians to use mobile laser services. Utilization of a mobile laser service allows physicians to provide the latest treatments for their patients while minimizing overhead costs. The high capital expense of laser systems is often beyond the financial means of individual clinicians, group practices, free-standing clinics and smaller community hospitals. Historically rapid technology turnover with laser technology places additional risk which is unacceptable to many institutions. In addition, health care reform is mandating consolidation of equipment within health care groups to keep costs at a minimum. In 1994, Abbott Northwestern Hospital organized an in-house mobile laser technology service which employs a group of experienced laser specialists to deliver and support laser treatments for hospital outreach and other regional physicians and health care facilities. Many of the hospital's internal safety standards and policies are applicable to the mobile environment. A significant challenge is client compliance because of the delicate balance of managing risk while avoiding being viewed as a regulator. The clinics and hospitals are assessed prior to service to assure minimum laser safety standards for both the patient and the staff. A major component in assessing new sites is to inform them of applicable regulatory standards and their obligations to assure optimum laser safety. In service training is provided and hospital and procedures are freely shared to assist the client in establishing a safe laser environment. Physician and nursing preceptor programs are also made available.
X-ray laser system, x-ray laser and method
London, Richard A.; Rosen, Mordecai D.; Strauss, Moshe
1992-01-01
Disclosed is an x-ray laser system comprising a laser containing generating means for emitting short wave length radiation, and means external to said laser for energizing said generating means, wherein when the laser is in an operative mode emitting radiation, the radiation has a transverse coherence length to width ratio of from about 0.05 to 1. Also disclosed is a method of adjusting the parameters of the laser to achieve the desired coherence length to laser width ratio.
Rigrod laser-pumped-laser resonator model: II. Application to thin and optically-dilute laser media
NASA Astrophysics Data System (ADS)
Brown, D. C.
2014-08-01
In part I of this paper, and to set the foundation for this part II, we derived the resonator equations describing the normalized intensities, output power, gain, and extraction efficiency for a standard resonator incorporating two dielectric mirrors and a gain element. We then generalized the results to include an absorbing region representing a second laser crystal characterized by a small-signal transmission T0. Explicit expressions were found for the output power extracted into absorption by the second laser crystal and the extraction efficiency, and the limits to each were discussed. It was shown that efficient absorption by a thin or dilute second laser crystal can be realized in resonators in which the mirror reflectivities were high and in which the single-pass absorption was low, due to the finite photon lifetime and multi-passing of the absorbing laser element. In this paper, we apply the model derived in part I to thin or dilute laser materials, concentrating on a Yb, Er:glass intracavity pumped by a 946 nm Nd:YAG laser, a Yb, Er:glass laser-pumped intracavity by a 977 nm diode laser, and an Er:YAG laser-pumped intracavity to a 1530 nm diode laser. It is shown that efficient absorption can be obtained in all cases examined.
Biogeochemical Cycling of Manganese at Hydrothermal Vents
1990-01-01
from an anoxic basin) contain the gene for the large subunit of Ribulose- 1,5-bisphosphate Carboxylase Oxygenase ( RubisCO ) suggestive of autotrophy... RubisCO gene probing on the bacterial isolates obtained from the hydrothermal vent environments as part of an ongoing ONR contract. In addition, we have...to test the feasibility of using gene probes for Ribulose-l,5- bisphosphate Carboxylase Oxygenase ( RubisCO ) for identifying autotrophic Mn(II
The Geoscience Laser Altimeter System Laser Transmitter
NASA Technical Reports Server (NTRS)
Afzal, R. S.; Dallas, J. L.; Yu, A. W.; Mamakos, W. A.; Lukemire, A.; Schroeder, B.; Malak, A.
2000-01-01
The Geoscience Laser Altimeter System (GLAS), scheduled to launch in 2001, is a laser altimeter and lidar for tile Earth Observing System's (EOS) ICESat mission. The laser transmitter requirements, design and qualification test results for this space- based remote sensing instrument are presented.
Auto-simultaneous laser treatment and Ohshiro's classification of laser treatment
NASA Astrophysics Data System (ADS)
Ohshiro, Toshio
2005-07-01
When the laser was first applied in medicine and surgery in the late 1960"s and early 1970"s, early adopters reported better wound healing and less postoperative pain with laser procedures compared with the same procedure performed with the cold scalpel or with electrothermy, and multiple surgical effects such as incision, vaporization and hemocoagulation could be achieved with the same laser beam. There was thus an added beneficial component which was associated only with laser surgery. This was first recognized as the `?-effect", was then classified by the author as simultaneous laser therapy, but is now more accurately classified by the author as part of the auto-simultaneous aspect of laser treatment. Indeed, with the dramatic increase of the applications of the laser in surgery and medicine over the last 2 decades there has been a parallel increase in the need for a standardized classification of laser treatment. Some classifications have been machine-based, and thus inaccurate because at appropriate parameters, a `low-power laser" can produce a surgical effect and a `high power laser", a therapeutic one . A more accurate classification based on the tissue reaction is presented, developed by the author. In addition to this, the author has devised a graphical representation of laser surgical and therapeutic beams whereby the laser type, parameters, penetration depth, and tissue reaction can all be shown in a single illustration, which the author has termed the `Laser Apple", due to the typical pattern generated when a laser beam is incident on tissue. Laser/tissue reactions fall into three broad groups. If the photoreaction in the tissue is irreversible, then it is classified as high-reactive level laser treatment (HLLT). If some irreversible damage occurs together with reversible photodamage, as in tissue welding, the author refers to this as mid-reactive level laser treatment (MLLT). If the level of reaction in the target tissue is lower than the cells
Studies on lasers and laser devices
NASA Technical Reports Server (NTRS)
Harris, S. E.; Siegman, A. E.; Young, J. F.
1983-01-01
The goal of this grant was to study lasers, laser devices, and uses of lasers for investigating physical phenomena are studied. The active projects included the development of a tunable, narrowband XUV light source and its application to the spectroscopy of core excited atomic states, and the development of a technique for picosecond time resolution spectroscopy of fast photophysical processes.
The Geoscience Laser Altimeter System (GLAS) Laser Transmitter
NASA Technical Reports Server (NTRS)
Afzal, Robert S.; Yu, Anthony W.; Dallas, Joseph L.; Melak, Anthony; Lukemir, Alan; Ramos-Izqueirdo, L.; Mamakos, William
2007-01-01
The Geoscience Laser Altimeter System (GLAS), launched in January 2003, is a laser altimeter and lidar for the Earth Observing System's (EOS) ICESat mission. GLAS accommodates three, sequentially operated, diode-pumped, solid-state, Nd:YAG laser transmitters. The laser transmitter requirements, design and qualification test results for this space-based remote sensing instrument is summarized and presented
Femtosecond laser in laser in situ keratomileusis
Salomão, Marcella Q.; Wilson, Steven E.
2014-01-01
Flap creation is a critical step in laser in situ keratomileusis (LASIK). Efforts to improve the safety and predictability of the lamellar incision have fostered the development of femtosecond lasers. Several advantages of the femtosecond laser over mechanical microkeratomes have been reported in LASIK surgery. In this article, we review common considerations in management and complications of this step in femtosecond laser–LASIK and concentrate primarily on the IntraLase laser because most published studies relate to this instrument. PMID:20494777
Laser plasma interaction at an early stage of laser ablation
NASA Astrophysics Data System (ADS)
Lu, Y. F.; Hong, M. H.; Low, T. S.
1999-03-01
Laser scattering and its interaction with plasma during KrF excimer laser ablation of silicon are investigated by ultrafast phototube detection. There are two peaks in an optical signal with the first peak attributed to laser scattering and the second one to plasma generation. For laser fluence above 5.8 J/cm2, the second peak rises earlier to overlap with the first one. The optical signal is fitted by a pulse distribution for the scattered laser light and a drifted Maxwell-Boltzmann distribution with a center-of-mass velocity for the plasma. Peak amplitude and its arrival time, full width at half maximum (FWHM), starting time, and termination time of the profiles are studied for different laser fluences and detection angles. Laser pulse is scattered from both the substrate and the plasma with the latter part as a dominant factor during the laser ablation. Peak amplitude of the scattered laser signal increases but its FWHM decreases with the laser fluence. Angular distribution of the peak amplitude can be fitted with cosn θ(n=4) while the detection angle has no obvious influence on the FWHM. In addition, FWHM and peak amplitude of plasma signal increase with the laser fluence. However, starting time and peak arrival time of plasma signal reduce with the laser fluence. The time interval between plasma starting and scattered laser pulse termination is proposed as a quantitative parameter to characterize laser plasma interaction. Threshold fluence for the interaction is estimated to be 3.5 J/cm2. For laser fluence above 12.6 J/cm2, the plasma and scattered laser pulse distributions tend to saturate.
Ort, R J; Anderson, R R
1999-06-01
Traditional methods of hair removal have proven unsatisfactory for many individuals with excessive or unwanted hair. In the last few years, several lasers and xenon flashlamps have been developed that promise to fulfill the need for a practical, safe, and long-lasting method of hair removal. Aggressive marketing of these has contributed to their popularity among patients and physicians. However, significant controversy and confusion surrounds this field. This article provides a detailed explanation of the scientific underpinnings for optical hair removal and explores the advantages and disadvantages of the various devices currently available (Nd:YAG, ruby, alexandrite, diode lasers, and xenon flashlamp). Treatment and safety guidelines are provided to assist the practitioner in the use of these devices. Although the field of optical hair removal is still in its infancy, initial reports of long-term efficacy are encouraging.
Environmental testing of a diode-laser-pumped Nd:YAG laser and a set of diode-laser-arrays
NASA Technical Reports Server (NTRS)
Hemmati, H.; Lesh, J. R.
1989-01-01
Results of the environmental test of a compact, rigid and lightweight diode-laser-pumped Nd:YAG laser module are discussed. All optical elements are bonded onto the module using space applicable epoxy, and two 200 mW diode laser arrays for pump sources are used to achieve 126 mW of CW output with about 7 percent electrical-to-optical conversion efficiency. This laser assembly and a set of 20 semiconductor diode laser arrays were environmentally tested by being subjected to vibrational and thermal conditions similar to those experienced during launch of the Space Shuttle, and both performed well. Nevertheless, some damage to the laser front facet in diode lasers was observed. Significant degradation was observed only on lasers which performed poorly in the life test. Improvements in the reliability of the Nd:YAG laser are suggested.
NASA Technical Reports Server (NTRS)
1973-01-01
Laser communication technology and laser communication performance are reviewed. The subjects discussed are: (1) characteristics of laser communication systems, (2) laser technology problems, (3) means of overcoming laser technology problems, and (4) potential schedule for including laser communications into data acquisition networks. Various types of laser communication systems are described and their capabilities are defined.
Lewis, Owen; Stogran, Edmund M.
1980-01-01
Laser apparatus is described wherein an active laser element, such as the disc of a face-pumped laser, is mounted in a housing such that the weight of the element is supported by glass spheres which fill a chamber defined in the housing between the walls of the housing and the edges of the laser element. The uniform support provided by the spheres enable the chamber and the pump side of the laser element to be sealed without affecting the alignment or other optical properties of the laser element. Cooling fluid may be circulated through the sealed region by way of the interstices between the spheres. The spheres, and if desired also the cooling fluid may contain material which absorbs radiation at the wavelength of parasitic emissions from the laser element. These parasitic emissions enter the spheres through the interface along the edge surface of the laser element and it is desirable that the index of refraction of the spheres and cooling fluid be near the index of refraction of the laser element. Thus support, cooling, and parasitic suppression functions are all accomplished through the use of the arrangement.
Early, James W.; Lester, Charles S.
2002-01-01
In the apparatus of the invention, a first excitation laser or other excitation light source is used in tandem with an ignitor laser to provide a compact, durable, engine deployable fuel ignition laser system. The beam from the excitation light source is split with a portion of it going to the ignitor laser and a second portion of it being recombined with the first portion after a delay before injection into the ignitor laser. Reliable fuel ignition is provided over a wide range of fuel conditions by using a single remote excitation light source for one or more small lasers located proximate to one or more fuel combustion zones.
Consistency analysis on laser signal in laser guided weapon simulation
NASA Astrophysics Data System (ADS)
Yin, Ruiguang; Zhang, Wenpan; Guo, Hao; Gan, Lin
2015-10-01
The hardware-in-the-loop simulation is widely used in laser semi-active guidance weapon experiments, the authenticity of the laser guidance signal is the key problem of reliability. In order to evaluate the consistency of the laser guidance signal, this paper analyzes the angle of sight, laser energy density, laser spot size, atmospheric back scattering, sun radiation and SNR by comparing the different working state between actual condition and hardware-in-the-loop simulation. Based on measured data, mathematical simulation and optical simulation result, laser guidance signal effects on laser seeker are determined. By using Monte Carlo method, the laser guided weapon trajectory and impact point distribution are obtained, the influence of the systematic error are analyzed. In conclusion it is pointed out that the difference between simulation system and actual system has little influence in normal guidance, has great effect on laser jamming. The research is helpful to design and evaluation of laser guided weapon simulation.
Design and comparison of laser windows for high-power lasers
NASA Astrophysics Data System (ADS)
Niu, Yanxiong; Liu, Wenwen; Liu, Haixia; Wang, Caili; Niu, Haisha; Man, Da
2014-11-01
High-power laser systems are getting more and more widely used in industry and military affairs. It is necessary to develop a high-power laser system which can operate over long periods of time without appreciable degradation in performance. When a high-energy laser beam transmits through a laser window, it is possible that the permanent damage is caused to the window because of the energy absorption by window materials. So, when we design a high-power laser system, a suitable laser window material must be selected and the laser damage threshold of the window must be known. In this paper, a thermal analysis model of high-power laser window is established, and the relationship between the laser intensity and the thermal-stress field distribution is studied by deducing the formulas through utilizing the integral-transform method. The influence of window radius, thickness and laser intensity on the temperature and stress field distributions is analyzed. Then, the performance of K9 glass and the fused silica glass is compared, and the laser-induced damage mechanism is analyzed. Finally, the damage thresholds of laser windows are calculated. The results show that compared with K9 glass, the fused silica glass has a higher damage threshold due to its good thermodynamic properties. The presented theoretical analysis and simulation results are helpful for the design and selection of high-power laser windows.
Operation of Ho:YAG ultrafast laser inscribed waveguide lasers.
McDaniel, Sean; Thorburn, Fiona; Lancaster, Adam; Stites, Ronald; Cook, Gary; Kar, Ajoy
2017-04-20
We report fabrication and operation of multi-watt level waveguide lasers utilizing holmium-doped yttrium aluminum garnet (Ho:YAG). The waveguides were fabricated using ultrafast laser inscription, which relies on a chirped pulse ytterbium fiber laser to create depressed cladding structures inside the material. A variety of waveguides were created inside the Ho:YAG samples. We demonstrate output powers of ∼2 W from both a single-mode 50 μm waveguide laser and a multimode 80 μm waveguide laser. In addition, laser action from a co-doped Yb:Ho:YAG sample under in-band pumping conditions was demonstrated.
Biology of Symbioses between Marine Invertebrates and Intracellular Bacteria
1991-01-21
bisphosphate carboxylase ( RubisCO ) from symbiotic bacteria of various origins, b) To continue methods development for 16S rRNA sequencing from symbionts in...frozen and badly preserved specimens, and c) To use these new techniques to sequence 16s DNA from a variety of symbionts a) RubisCO We have cloned the...gene coding for RubisCO from the sulfur oxidixing symbiont of the gastropod Alvinochoncha hessleri. Nucleotide sequence analysis of the cloned fragment
Laser propulsion for orbit transfer - Laser technology issues
NASA Technical Reports Server (NTRS)
Horvath, J. C.; Frisbee, R. H.
1985-01-01
Using reasonable near-term mission traffic models (1991-2000 being the assumed operational time of the system) and the most current unclassified laser and laser thruster information available, it was found that space-based laser propulsion orbit transfer vehicles (OTVs) can outperform the aerobraked chemical OTV over a 10-year life-cycle. The conservative traffic models used resulted in an optimum laser power of about 1 MW per laser. This is significantly lower than the power levels considered in other studies. Trip time was taken into account only to the extent that the system was sized to accomplish the mission schedule.
Laser frequency modulator for modulating a laser cavity
Erbert, Gaylen V.
1992-01-01
The present invention relates to a laser frequency modulator for modulating a laser cavity. It is known in the prior art to utilize a PZT (piezoelectric transducer) element in combination with a mirror to change the cavity length of a laser cavity (which changes the laser frequency). Using a PZT element to drive the mirror directly is adequate at frequencies below 10 kHz. However, in high frequency applications (100 kHz and higher) PZT elements alone do not provide a sufficient change in the cavity length. The present invention utilizes an ultrasonic concentrator with a PZT element and mirror to provide modulation of the laser cavity. With an ultrasonic concentrator, the mirror element at the end of a laser cavity can move at larger amplitudes and higher frequencies.
ERIC Educational Resources Information Center
Gauger, Robert
1993-01-01
Describes lasers and indicates that learning about laser technology and creating laser technology activities are among the teacher enhancement processes needed to strengthen technology education. (JOW)
Early, James W.; Lester, Charles S.
2002-01-01
In the apparatus of the invention, a first excitation laser or other excitation light source is used in tandem with an ignitor laser to provide a compact, durable, engine deployable fuel ignition laser system. Reliable fuel ignition is provided over a wide range of fuel conditions by using a single remote excitation light source for one or more small lasers located proximate to one or more fuel combustion zones. In the embodiment of the invention claimed herein, the beam from the excitation light source is split with a portion of it going to the ignitor laser and a second portion of it being combined with either the first portion after a delay before injection into the ignitor laser.
High throughput laser processing
DOE Office of Scientific and Technical Information (OSTI.GOV)
Harley, Gabriel; Pass, Thomas; Cousins, Peter John
A solar cell is formed using a solar cell ablation system. The ablation system includes a single laser source and several laser scanners. The laser scanners include a master laser scanner, with the rest of the laser scanners being slaved to the master laser scanner. A laser beam from the laser source is split into several laser beams, with the laser beams being scanned onto corresponding wafers using the laser scanners in accordance with one or more patterns. The laser beams may be scanned on the wafers using the same or different power levels of the laser source.
Phasing surface emitting diode laser outputs into a coherent laser beam
Holzrichter, John F [Berkeley, CA
2006-10-10
A system for generating a powerful laser beam includes a first laser element and at least one additional laser element having a rear laser mirror, an output mirror that is 100% reflective at normal incidence and <5% reflective at an input beam angle, and laser material between the rear laser mirror and the output mirror. The system includes an injector, a reference laser beam source, an amplifier and phase conjugater, and a combiner.
Ytterbium-doped borate fluoride laser crystals and lasers
Schaffers, Kathleen I.; DeLoach, Laura D.; Payne, Stephen A.; Keszler, Douglas A.
1997-01-01
A new class of solid state laser crystals and lasers are formed from Yb-doped borate fluoride host crystals. The general formula for the host crystals is MM'(BO.sub.3)F, where M, M' are monovalent, divalent aria trivalent metal cations. A particular embodiment of the invention is Yb-doped BaCaBO.sub.3 F (Yb:BCBF). BCBF and some of the related derivative crystals are capable of nonlinear frequency conversion, whereby the fundamental of the laser is converted to a longer or shorter wavelength. In this way, these new crystals can simultaneously serve as self-frequency doubling crystals and laser materials within the laser resonator.
NASA Astrophysics Data System (ADS)
Kushina, Mark E.; Heberle, Geoff; Hope, Michael; Hall, David; Bethel, Michael; Calmes, Lonnie K.
2003-06-01
The ALMDS (Airborne Laser Mine Detection System) has been developed utilizing a solid-state laser operating at 532nm for naval mine detection. The laser system is integrated into a pod that mounts externally on a helicopter. This laser, along with other receiver systems, enables detailed underwater bathymetry. CEO designs and manufactures the laser portion of this system. Arete Associates integrates the laser system into the complete LIDAR package that utilizes sophisticated streak tube detection technology. Northrop Grumman is responsible for final pod integration. The laser sub-system is comprised of two separate parts: the LTU (Laser Transmitter Unit) and the LEU (Laser Electronics Unit). The LTU and LEU are undergoing MIL-STD-810 testing for vibration, shock, temperature storage and operation extremes, as well as MIL-STD-704E electrical power testing and MIL-STD-461E EMI testing. The Nd:YAG MOPA laser operates at 350 Hz pulse repetition frequency at 45 Watts average 532nm power and is controlled at the system level from within the helicopter. Power monitor circuits allow real time laser health monitoring, which enables input parameter adjustments for consistent laser behavior.
Histologic evaluation of laser lipolysis: pulsed 1064-nm Nd:YAG laser versus cw 980-nm diode laser.
Mordon, Serge; Eymard-Maurin, Anne Françoise; Wassmer, Benjamin; Ringot, Jean
2007-01-01
The use of the laser as an auxiliary tool has refined the traditional technique for lipoplasty. During laser lipolysis, the interaction between the laser and the fat produced direct cellular destruction before the suction, reduced bleeding, and promoted skin tightening. This study sought to perform a comparative histologic evaluation of laser lipolysis with the pulsed 1064-nm Nd:YAG laser versus a continuous 980-nm diode laser. A pulsed 1064-nm Nd:YAG (Smart-Lipo; Deka, Italy) and a CW 980-nm diode laser (Pharaon, Osyris, France) were evaluated at different energy settings for lipolysis on the thighs of a fresh cadaver. The lasers were coupled to a 600-microm optical fiber inserted in a 1-mm diameter cannula. Biopsy specimens were taken on irradiated and non-irradiated areas. Hematoxylin-erythrosin-safran staining and immunostaining (anti-PS100 polyclonal antibody) were performed to identify fat tissue damage. In the absence of laser exposures (control specimens), cavities created by cannulation were seen; adipocytes were round in appearance and not deflated. At low energy settings, tumescent adipocytes were observed. At higher energy settings, cytoplasmic retraction, disruption of membranes, and heat-coagulated collagen fibers were noted; coagulated blood cells were also present. For the highest energy settings, carbonization of fat tissue involving fibers and membranes was clearly seen. For equivalent energy settings, 1064-nm and 980-nm wavelengths gave similar histologic results. Laser lipolysis is a relatively new technique that is still under development. Our histologic findings suggest several positive benefits of the laser, including skin retraction and a reduction in intraoperative bleeding. The interaction of the laser with the tissue is similar at 980 nm and 1064 nm with the same energy settings. Because higher volumes of fat are removed with higher total energy, a high-power 980-nm diode laser could offer an interesting alternative to the 1064-nm Nd
Passeron, T
2012-12-01
Lasers are a very effective approach for treating many hyperpigmented lesions. They are the gold standard treatment for actinic lentigos and dermal hypermelanocytosis, such as Ota nevus. Becker nevus, hyperpigmented mosaicisms, and lentigines can also be successfully treated with lasers, but they could be less effective and relapses can be observed. However, lasers cannot be proposed for all types of hyperpigmentation. Thus, freckles and café-au-lait macules should not be treated as the relapses are nearly constant. Due to its complex pathophysiology, melasma has a special place in hyperpigmented dermatoses. Q-switched lasers (using standard parameters or low fluency) should not be used because of consistent relapses and the high risk of post-inflammatory hyperpigmentation. Paradoxically, targeting the vascular component of the melasma lesion with lasers could have a beneficial effect. However, these results have yet to be confirmed. In all cases, a precise diagnosis of the type of hyperpigmentation is mandatory before any laser treatment, and the limits and the potential side effects of the treatment must be clearly explained to patients. Copyright © 2012 Elsevier Masson SAS. All rights reserved.
Passeron, T
2012-11-01
Lasers are a very effective approach for treating many hyperpigmented lesions. They are the gold standard treatment for actinic lentigos and dermal hypermelanocytosis, such as Ota nevus. Becker nevus, hyperpigmented mosaicisms, and lentigines can also be successfully treated with lasers, but they could be less effective and relapses can be observed. However, lasers cannot be proposed for all types of hyperpigmentation. Thus, freckles and café-au-lait macules should not be treated as the relapses are nearly constant. Due to its complex pathophysiology, melasma has a special place in hyperpigmented dermatoses. Q-switched lasers (using standard parameters or low fluency) should not be used because of consistent relapses and the high risk of post-inflammatory hyperpigmentation. Paradoxically, targeting the vascular component of the melasma lesion with lasers could have a beneficial effect. However, these results have yet to be confirmed. In all cases, a precise diagnosis of the type of hyperpigmentation is mandatory before any laser treatment, and the limits and the potential side effects of the treatment must be clearly explained to patients. Copyright © 2012 Elsevier Masson SAS. All rights reserved.
Laser coagulation; Laser eye surgery; Photocoagulation; Laser photocoagulation - diabetic eye disease; Laser photocoagulation - diabetic retinopathy; Focal photocoagulation; Scatter (or pan retinal) photocoagulation; Proliferative ...
Cantrell, Cyrus D.; Carbone, Robert J.; Cooper, Ralph S.
1977-01-01
An infrared laser system and method for isotope separation may comprise a molecular gas laser oscillator to produce a laser beam at a first wavelength, Raman spin flip means for shifting the laser to a second wavelength, a molecular gas laser amplifier to amplify said second wavelength laser beam to high power, and optical means for directing the second wavelength, high power laser beam against a desired isotope for selective excitation thereof in a mixture with other isotopes. The optical means may include a medium which shifts the second wavelength high power laser beam to a third wavelength, high power laser beam at a wavelength coincidental with a corresponding vibrational state of said isotope and which is different from vibrational states of other isotopes in the gas mixture.
Cantrell, Cyrus D.; Carbone, Robert J.; Cooper, Ralph
1982-01-01
An infrared laser system and method for isotope separation may comprise a molecular gas laser oscillator to produce a laser beam at a first wavelength, Raman spin flip means for shifting the laser to a second wavelength, a molecular gas laser amplifier to amplify said second wavelength laser beam to high power, and optical means for directing the second wavelength, high power laser beam against a desired isotope for selective excitation thereof in a mixture with other isotopes. The optical means may include a medium which shifts the second wavelength high power laser beam to a third wavelength, high power laser beam at a wavelength coincidental with a corresponding vibrational state of said isotope and which is different from vibrational states of other isotopes in the gas mixture.
Sanghera, Jasbinder; Kim, Woohong; Villalobos, Guillermo; Shaw, Brandon; Baker, Colin; Frantz, Jesse; Sadowski, Bryan; Aggarwal, Ishwar
2012-01-01
Ceramic laser materials have come a long way since the first demonstration of lasing in 1964. Improvements in powder synthesis and ceramic sintering as well as novel ideas have led to notable achievements. These include the first Nd:yttrium aluminum garnet (YAG) ceramic laser in 1995, breaking the 1 KW mark in 2002 and then the remarkable demonstration of more than 100 KW output power from a YAG ceramic laser system in 2009. Additional developments have included highly doped microchip lasers, ultrashort pulse lasers, novel materials such as sesquioxides, fluoride ceramic lasers, selenide ceramic lasers in the 2 to 3 μm region, composite ceramic lasers for better thermal management, and single crystal lasers derived from polycrystalline ceramics. This paper highlights some of these notable achievements. PMID:28817044
Laser-diode pumped 40-W Yb:YAG ceramic laser.
Hao, Qiang; Li, Wenxue; Pan, Haifeng; Zhang, Xiaoyi; Jiang, Benxue; Pan, Yubai; Zeng, Heping
2009-09-28
We demonstrated a high-power continuous-wave (CW) polycrystalline Yb:YAG ceramic laser pumped by fiber-pigtailed laser diode at 968 nm with 400 mum fiber core. The Yb:YAG ceramic laser performance was compared for different Yb(3+) ion concentrations in the ceramics by using a conventional end-pump laser cavity consisting of two flat mirrors with output couplers of different transmissions. A CW laser output of 40 W average power with M(2) factor of 5.8 was obtained with 5 mol% Yb concentration under 120 W incident pump power. This is to the best of our knowledge the highest output power in end-pumped bulk Yb:YAG ceramic laser.
Laser cutting: industrial relevance, process optimization, and laser safety
NASA Astrophysics Data System (ADS)
Haferkamp, Heinz; Goede, Martin; von Busse, Alexander; Thuerk, Oliver
1998-09-01
Compared to other technological relevant laser machining processes, up to now laser cutting is the application most frequently used. With respect to the large amount of possible fields of application and the variety of different materials that can be machined, this technology has reached a stable position within the world market of material processing. Reachable machining quality for laser beam cutting is influenced by various laser and process parameters. Process integrated quality techniques have to be applied to ensure high-quality products and a cost effective use of the laser manufacturing plant. Therefore, rugged and versatile online process monitoring techniques at an affordable price would be desirable. Methods for the characterization of single plant components (e.g. laser source and optical path) have to be substituted by an omnivalent control system, capable of process data acquisition and analysis as well as the automatic adaptation of machining and laser parameters to changes in process and ambient conditions. At the Laser Zentrum Hannover eV, locally highly resolved thermographic measurements of the temperature distribution within the processing zone using cost effective measuring devices are performed. Characteristic values for cutting quality and plunge control as well as for the optimization of the surface roughness at the cutting edges can be deducted from the spatial distribution of the temperature field and the measured temperature gradients. Main influencing parameters on the temperature characteristic within the cutting zone are the laser beam intensity and pulse duration in pulse operation mode. For continuous operation mode, the temperature distribution is mainly determined by the laser output power related to the cutting velocity. With higher cutting velocities temperatures at the cutting front increase, reaching their maximum at the optimum cutting velocity. Here absorption of the incident laser radiation is drastically increased due to
Ultrafast pulsed laser utilizing broad bandwidth laser glass
Payne, Stephen A.; Hayden, Joseph S.
1997-01-01
An ultrafast laser uses a Nd-doped phosphate laser glass characterized by a particularly broad emission bandwidth to generate the shortest possible output pulses. The laser glass is composed primarily of P.sub.2 O.sub.5, Al.sub.2 O.sub.3 and MgO, and possesses physical and thermal properties that are compatible with standard melting and manufacturing methods. The broad bandwidth laser glass can be used in modelocked oscillators as well as in amplifier modules.
NASA Technical Reports Server (NTRS)
Lucas, John F.; Hornef, James
2016-01-01
This project's goal is the design of a Raman spectroscopy instrument to be utilized by NASA in an integrated spectroscopy strategy that will include Laser-Induced Breakdown Spectroscopy (LIBS) and Laser-Induced Florescence Spectroscopy (LIFS) for molecule and element identification on Mars Europa, and various asteroids. The instrument is to be down scaled from a dedicated rover mounted instrument into a compact unit with the same capabilities and accuracy as the larger instrument. The focus for this design is a spectrometer that utilizes Raman spectroscopy. The spectrometer has a calculated range of 218 nm wavelength spectrum with a resolution of 1.23 nm. To filter out the laser source wavelength of 532 nm the spectrometer design utilizes a 532 nm wavelength dichroic mirror and a 532 nm wavelength notch filter. The remaining scatter signal is concentrated by a 20 x microscopic objective through a 25-micron vertical slit into a 5mm diameter, 1cm focal length double concave focusing lens. The light is then diffracted by a 1600 Lines per Millimeter (L/mm) dual holographic transmission grating. This spectrum signal is captured by a 1-inch diameter double convex 3 cm focal length capture lens. An Intensified Charge Couple Device (ICCD) is placed within the initial focal cone of the capture lens and the Raman signal captured is to be analyzed through spectroscopy imaging software. This combination allows for accurate Raman spectroscopy to be achieved. The components for the spectrometer have been bench tested in a series of prototype developments based on theoretical calculations, alignment, and scaling strategies. The mounting platform is 2.5 cm wide by 8.8 cm long by 7 cm height. This platform has been tested and calibrated with various sources such as a neon light source and ruby crystal. This platform is intended to be enclosed in a ruggedized enclosure for mounting on a rover platform. The size and functionality of the Raman spectrometer allows for the rover to
Ytterbium-doped borate fluoride laser crystals and lasers
Schaffers, K.I.; DeLoach, L.D.; Payne, S.A.; Keszler, D.A.
1997-10-14
A new class of solid state laser crystals and lasers are formed from Yb-doped borate fluoride host crystals. The general formula for the host crystals is MM{prime}(BO{sub 3})F, where M, M{prime} are monovalent, divalent aria trivalent metal cations. A particular embodiment of the invention is Yb-doped BaCaBO{sub 3}F (Yb:BCBF). BCBF and some of the related derivative crystals are capable of nonlinear frequency conversion, whereby the fundamental of the laser is converted to a longer or shorter wavelength. In this way, these new crystals can simultaneously serve as self-frequency doubling crystals and laser materials within the laser resonator. 6 figs.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dr. Alan Chodos; Elizabeth A. Rogan
LaserFest was the yearlong celebration, during 2010, of the 50th anniversary of the demonstration of the first working laser. The goals of LaserFest were: to highlight the impact of the laser in its manifold commercial, industrial and medical applications, and as a tool for ongoing scientific research; to use the laser as one example that illustrates, more generally, the route from scientific innovation to technological application; to use the laser as a vehicle for outreach, to stimulate interest among students and the public in aspects of physical science; to recognize and honor the pioneers who developed the laser and itsmore » many applications; to increase awareness among policymakers of the importance of R&D funding as evidenced by such technology as lasers. One way in which LaserFest sought to meet its goals was to encourage relevant activities at a local level all across the country -- and also abroad -- that would be identified with the larger purposes of the celebration and would carry the LaserFest name. Organizers were encouraged to record and advertise these events through a continually updated web-based calendar. Four projects were explicitly detailed in the proposals: 1) LaserFest on the Road; 2) Videos; 3) Educational material; and 4) Laser Days.« less
Laser Ablation of Biological Tissue Using Pulsed CO{sub 2} Laser
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hashishin, Yuichi; Sano, Shu; Nakayama, Takeyoshi
2010-10-13
Laser scalpels are currently used as a form of laser treatment. However, their ablation mechanism has not been clarified because laser excision of biological tissue occurs over a short time scale. Biological tissue ablation generates sound (laser-induced sound). This study seeks to clarify the ablation mechanism. The state of the gelatin ablation was determined using a high-speed video camera and the power reduction of a He-Ne laser beam. The aim of this study was to clarify the laser ablation mechanism by observing laser excision using the high-speed video camera and monitoring the power reduction of the He-Ne laser beam. Wemore » simulated laser excision of a biological tissue by irradiating gelatin (10 wt%) with radiation from a pulsed CO{sub 2} laser (wavelength: 10.6 {mu}m; pulse width: 80 ns). In addition, a microphone was used to measure the laser-induced sound. The first pulse caused ablation particles to be emitted in all directions; these particles were subsequently damped so that they formed a mushroom cloud. Furthermore, water was initially evaporated by laser irradiation and then tissue was ejected.« less
Observation of laser beam profile progression inside an extended laser cavity
NASA Astrophysics Data System (ADS)
Wu, Frank F.; Farrell, Thomas C.
2013-03-01
This report presents the result of the laser beam profile progression in target-in-the-loop (TIL) system. This simulation experiment is to verify whether it is possible to form a tight hot spot similar to a single transversal mode in an extended laser cavity. Therefore, it is very important to observe the progression of the laser profile at a laser cavity mirror when a seeded high energy laser pulse is injected into the TIL system. The extended laser cavity is formed with a high reflectivity mirror on one end and an optical phase conjugated mirror as the second mirror, with potential disturbance media inside. The laser oscillation occurs only when it is triggered with a single frequency high energy laser pulse to overcome the threshold condition. With a laser cavity length of around 11 meters and a seeded laser pulse of 10 ns, we have been able to acquire and distinguish the laser beam profiles of each round-trip. Inserting a scattering media and other distortion elements can simulate atmospheric effects.
Development of high-power CO2 lasers and laser material processing
NASA Astrophysics Data System (ADS)
Nath, Ashish K.; Choudhary, Praveen; Kumar, Manoj; Kaul, R.
2000-02-01
Scaling laws to determine the physical dimensions of the active medium and optical resonator parameters for designing convective cooled CO2 lasers have been established. High power CW CO2 lasers upto 5 kW output power and a high repetition rate TEA CO2 laser of 500 Hz and 500 W average power incorporated with a novel scheme for uniform UV pre- ionization have been developed for material processing applications. Technical viability of laser processing of several engineering components, for example laser surface hardening of fine teeth of files, laser welding of martensitic steel shroud and titanium alloy under-strap of turbine, laser cladding of Ni super-alloy with stellite for refurbishing turbine blades were established using these lasers. Laser alloying of pre-placed SiC coating on different types of aluminum alloy, commercially pure titanium and Ti-6Al-4V alloy, and laser curing of thermosetting powder coating have been also studied. Development of these lasers and results of some of the processing studies are briefly presented here.
Ultrafast pulsed laser utilizing broad bandwidth laser glass
Payne, S.A.; Hayden, J.S.
1997-09-02
An ultrafast laser uses a Nd-doped phosphate laser glass characterized by a particularly broad emission bandwidth to generate the shortest possible output pulses. The laser glass is composed primarily of P{sub 2}O{sub 5}, Al{sub 2}O{sub 3} and MgO, and possesses physical and thermal properties that are compatible with standard melting and manufacturing methods. The broad bandwidth laser glass can be used in modelocked oscillators as well as in amplifier modules. 7 figs.
Cyanobacterial-based approaches to improving photosynthesis in plants.
Zarzycki, Jan; Axen, Seth D; Kinney, James N; Kerfeld, Cheryl A
2013-01-01
Plants rely on the Calvin-Benson (CB) cycle for CO(2) fixation. The key carboxylase of the CB cycle is ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO). Efforts to enhance carbon fixation in plants have traditionally focused on RubisCO or on approaches that can help to remedy RubisCO's undesirable traits: its low catalytic efficiency and photorespiration. Towards reaching the goal of improving plant photosynthesis, cyanobacteria may be instrumental. Because of their evolutionary relationship to chloroplasts, they represent ideal model organisms for photosynthesis research. Furthermore, the molecular understanding of cyanobacterial carbon fixation provides a rich source of strategies that can be exploited for the bioengineering of chloroplasts. These strategies include the cyanobacterial carbon concentrating mechanism (CCM), which consists of active and passive transporter systems for inorganic carbon and a specialized organelle, the carboxysome. The carboxysome encapsulates RubisCO together with carbonic anhydrase in a protein shell, resulting in an elevated CO(2) concentration around RubisCO. Moreover, cyanobacteria differ from plants in the isoenzymes involved in the CB cycle and the photorespiratory pathways as well as in mechanisms that can affect the activity of RubisCO. In addition, newly available cyanobacterial genome sequence data from the CyanoGEBA project, which has more than doubled the amount of genomic information available for cyanobacteria, increases our knowledge on the CCM and the occurrence and distribution of genes of interest.
Long term productivity of canvasbacks (Aythya valisineria) in a snowpack-driven desert marsh
Kruse, Kammie L.; Lovvorn, James R.; Takekawa, John Y.; Mackay, Jeffrey
2003-01-01
Ruby Lake, Nevada, is a large palustrine wetland that hosts the southern-most major breeding population of Canvasbacks (Aythya valisineria). That arid marsh, fed by springs derived from mountain snowpack, differs in climate and hydrology from glaciated potholes of the northern prairies where most Canvasbacks breed. Fourteen years of nesting data on Canvasbacks over a 31 year period (1970–2000) were analyzed to determine factors affecting breeding performance at Ruby Lake and whether they differed from those in the prairies. Long-term Mayfield nest success at Ruby Lake (50% of all nests) was in the range of that in the northern prairies (21–65%). Of all Canvasback nests, 73% were parasitized (mostly by Redheads [Aythya americana]) as compared to 83–97% in a large Manitoba marsh and 57–65% in Manitoba potholes. However, as in the northern prairies, nest parasitism generally had little or no effect on either nest success or percentage of host eggs that hatched. In Manitoba potholes, nest success was unrelated to habitat variables measured; but successful nests at Ruby Lake were over shallower water, farther from shore, in wider bands of emergent vegetation, and surrounded by lower stem densities than unsuccessful nests. Water level is the key factor in breeding performance of Canvasbacks at both Ruby Lake and the northern prairies; however, the source of water differs (mountain snowpack at Ruby Lake, direct precipitation in the prairies) and effects of water-level variations are reversed. In small prairie potholes (mostly <0.4 ha) with many mammalian predators, productivity of Canvasbacks (which build floating nests) is increased by high water that floods the emergent fringe. At Ruby Lake, a very large marsh (2,830 ha) with mostly avian predators, Canvasback productivity is decreased by high water that floods interior emergent stands too deeply. Water level at Ruby Lake was highly correlated (multiple R2 = 0.91) with mountain snowpack up to three years earlier
Laser application in neurosurgery
Belykh, Evgenii; Yagmurlu, Kaan; Martirosyan, Nikolay L.; Lei, Ting; Izadyyazdanabadi, Mohammadhassan; Malik, Kashif M.; Byvaltsev, Vadim A.; Nakaji, Peter; Preul, Mark C.
2017-01-01
Background: Technological innovations based on light amplification created by stimulated emission of radiation (LASER) have been used extensively in the field of neurosurgery. Methods: We reviewed the medical literature to identify current laser-based technological applications for surgical, diagnostic, and therapeutic uses in neurosurgery. Results: Surgical applications of laser technology reported in the literature include percutaneous laser ablation of brain tissue, the use of surgical lasers in open and endoscopic cranial surgeries, laser-assisted microanastomosis, and photodynamic therapy for brain tumors. Laser systems are also used for intervertebral disk degeneration treatment, therapeutic applications of laser energy for transcranial laser therapy and nerve regeneration, and novel diagnostic laser-based technologies (e.g., laser scanning endomicroscopy and Raman spectroscopy) that are used for interrogation of pathological tissue. Conclusion: Despite controversy over the use of lasers for treatment, the surgical application of lasers for minimally invasive procedures shows promising results and merits further investigation. Laser-based microscopy imaging devices have been developed and miniaturized to be used intraoperatively for rapid pathological diagnosis. The multitude of ways that lasers are used in neurosurgery and in related neuroclinical situations is a testament to the technological advancements and practicality of laser science. PMID:29204309
Development of Laser Propulsion and Tracking System for Laser-Driven Micro-Airplane
NASA Astrophysics Data System (ADS)
Ishikawa, Hiroyasu; Kajiwara, Itsuro; Hoshino, Kentaro; Yabe, Takashi; Uchida, Shigeaki; Shimane, Yoshichika
2004-03-01
The purposes of this paper are to improve the control performance of the developed laser tracking system and to develop an integrated laser propulsion/tracking system for realizing a continuous flight and control of the micro-airplane. The laser propulsion is significantly effective to achieve the miniaturization and lightening of the micro-airplane. The laser-driven micro-airplane has been studied with a paper-craft airplane and YAG laser, resulting in a successful glide of the airplane. In the next stage of the laser-driven micro-airplane development, the laser tracking is expected as key technologies to achieve continuous propulsion. Furthermore, the laser propulsion system should be combined with the laser tracking system to supply continuous propulsion. Experiments are carried out to evaluate the performance of the developed laser tracking system and integrated laser propulsion/tracking system.
Hutchinson, Donald P.; Richards, Roger K.
2003-07-22
A micro-laser is disclosed which includes a waveguide, a first and a second subwavelength resonant grating in the waveguide, and at least one photonic band gap resonant structure (PBG) in the waveguide and at least one amplifying medium in the waveguide. PBG features are positioned between the first and second subwavelength resonant gratings and allow introduction of amplifying mediums into the highly resonant guided micro-laser microcavity. The micro-laser may be positioned on a die of a bulk substrate material with one or more electronic and optical devices and may be communicably connected to the same. A method for fabricating a micro-laser is disclosed. A method for tuning the micro-laser is also disclosed. The micro-laser may be used as an optical regenerator, or a light source for data transfer or for optical computing.
Research investigation directed toward extending the useful range of the electromagnetic spectrum
NASA Technical Reports Server (NTRS)
Hartmann, S. R.
1971-01-01
The lifetimes and fine structure of He(-) were studied using time-of-flight techniques and quenching by a static axial magnetic field. Using level-crossing spectroscopy the hyperfine constants A and B and the lifetime of the 3 2P3/2 state of Li-7 were measured. Polarization of the Ru 7S level was created as a first step in determining the hyperfine structure of the alkali excited S state. The parametric interaction between light and microwaves in optically pumped Rb-87 vapor were investigated. Measurements and analyses of transitions in formaldehyde and its isotopic species and in the lowest two excited vibrational states of H2CO were also made, as well as of transitions in furan, pyrrole, formic acid, and cyanoacetylene. The Hanle effect was studied in the NO molecule, and RF oscillators were developed with flat, wideband output to observe excited state hyperfine transitions at zero field. Data was generated on the time-dependent behavior of photon echoes in ruby. Stimulated Raman scattering was studied in atomic Tl vapor. A Q switched, temperature-tuned ruby laser was developed which operates between 6934 and 6938 A. The frequency shift due to resonant interaction between identical radiating atoms was calculated.
Fiber Optic Laser Accelerometer
2007-11-06
embodiment of a fiber laser accelerometer 10. The fiber laser accelerometer 10 includes a fiber laser 12. Fiber laser 12 can be either a Fabry - Perot type...cavity fiber laser or a distributed feedback fiber laser. In a 4 Attorney Docket No. 97966 Fabry - Perot type fiber laser, the laser cavity is a length...type of signal. A receiver 26 receives the phase shifted signal. Receiver 26 is capable of demodulating and detecting the signal from the fiber laser by
Fornaini, Carlo; Passaretti, Francesca; Villa, Elena; Rocca, Jean-Paul; Merigo, Elisabetta; Vescovi, Paolo; Meleti, Marco; Manfredi, Maddalena; Nammour, Samir
2011-07-01
The Nd:YAG laser has been used since 1970 in dental laboratories to weld metals on dental prostheses. Recently in several clinical cases, we have suggested that the Nd:YAG laser device commonly utilized in the dental office could be used to repair broken fixed, removable and orthodontic prostheses and to weld metals directly in the mouth. The aim of this work was to evaluate, using scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS) and dynamic mechanical analysis (DMA), the quality of the weld and its mechanical strength, comparing a device normally used in dental laboratory and a device normally used in the dental office for oral surgery, the same as that described for intraoral welding. Metal plates of a Co-Cr-Mo dental alloy and steel orthodontic wires were subjected to four welding procedures: welding without filler metal using the laboratory laser, welding with filler metal using the laboratory laser, welding without filler metal using the office laser, and welding with filler metal using the office laser. The welded materials were then analysed by SEM, EDS and DMA. SEM analysis did not show significant differences between the samples although the plates welded using the office laser without filler metal showed a greater number of fissures than the other samples. EDS microanalysis of the welding zone showed a homogeneous composition of the metals. Mechanical tests showed similar elastic behaviours of the samples, with minimal differences between the samples welded with the two devices. No wire broke even under the maximum force applied by the analyser. This study seems to demonstrate that the welds produced using the office Nd:YAG laser device and the laboratory Nd:YAG laser device, as analysed by SEM, EDS and DMA, showed minimal and nonsignificant differences, although these findings need to be confirmed using a greater number of samples.
NASA Astrophysics Data System (ADS)
Pais Clemente, Manuel P.
1992-03-01
Lasers are now commonly accepted and widely used surgical instruments in otorhinolaryngology. There have been a great number of technological advances with lasers that have contributed to the expansion of this new surgical modality with an increased number of medical applications. Surgical strategies have also changed and are more favorable toward conservative surgery in which less tissues is removed than with more radical resections. This combination of improving technology and medical attitudes has changed the field of otorhinolaryngology, and resulted in an expanding use of laser surgery. Since 1973 we have been using the carbon dioxide laser in the treatment of diseases of the upper aero digestive systems, learning this new surgical technique from the pioneer work of Strong, Jako, and Vaughan. It is our conviction that a laser surgeon must have a thorough knowledge of laser biophysics, instrumentation, safety protocols, and surgical indications, and have the technical skills to perform laser surgery. Laser technology continues to improve at an increased speed, and it is imperative to update knowledge of current and potential applications of lasers in our specialty. It is the purpose of this article to present our clinical experience of 18 years with the use of lasers in surgery of ORL, emphasizing the carbon dioxide laser.
Compact Hybrid Laser Rod and Laser System
NASA Technical Reports Server (NTRS)
Pierrottet, Diego F. (Inventor); Busch, George E. (Inventor); Amzajerdian, Farzin (Inventor)
2017-01-01
A hybrid fiber rod includes a fiber core and inner and outer cladding layers. The core is doped with an active element. The inner cladding layer surrounds the core, and has a refractive index substantially equal to that of the core. The outer cladding layer surrounds the inner cladding layer, and has a refractive index less than that of the core and inner cladding layer. The core length is about 30 to 2000 times the core diameter. A hybrid fiber rod laser system includes an oscillator laser, modulating device, the rod, and pump laser diode(s) energizing the rod from opposite ends. The rod acts as a waveguide for pump radiation but allows for free-space propagation of laser radiation. The rod may be used in a laser resonator. The core length is less than about twice the Rayleigh range. Degradation from single-mode to multi-mode beam propagation is thus avoided.
Theoretical comparison of maser materials for a 32-GHz maser amplifier
NASA Technical Reports Server (NTRS)
Lyons, James R.
1988-01-01
The computational results of a comparison of maser materials for a 32 GHz maser amplifier are presented. The search for a better maser material is prompted by the relatively large amount of pump power required to sustain a population inversion in ruby at frequencies on the order of 30 GHz and above. The general requirements of a maser material and the specific problems with ruby are outlined. The spin Hamiltonian is used to calculate energy levels and transition probabilities for ruby and twelve other materials. A table is compiled of several attractive operating points for each of the materials analyzed. All the materials analyzed possess operating points that could be superior to ruby. To complete the evaluation of the materials, measurements of inversion ratio and pump power requirements must be made in the future.
Kulikov, Alexei N; Maltsev, Dmitrii S; Boiko, Ernest V
2016-01-01
Purpose . To compare three 360°-laser retinopexy (LRP) approaches (using navigated pattern laser system, single-spot slit-lamp (SL) laser delivery, and single-spot indirect ophthalmoscope (IO) laser delivery) in regard to procedure duration, procedural pain score, technical difficulties, and the ability to achieve surgical goals. Material and Methods . Eighty-six rhegmatogenous retinal detachment patients (86 eyes) were included in this prospective randomized study. The mean procedural time, procedural pain score (using 4-point Verbal Rating Scale), number of laser burns, and achievement of the surgical goals were compared between three groups (pattern LRP (Navilas® laser system), 36 patients; SL-LRP, 28 patients; and IO-LRP, 22 patients). Results . In the pattern LRP group, the amount of time needed for LRP and pain level were statistically significantly lower, whereas the number of applied laser burns was higher compared to those in the SL-LRP group and in the IO-LRP group. In the pattern LRP, SL-LRP, and IO-LRP groups, surgical goals were fully achieved in 28 (77.8%), 17 (60.7%), and 13 patients (59.1%), respectively ( p > 0.05). Conclusion . The navigated pattern approach allows improving the treatment time and pain in postoperative 360° LRP. Moreover, 360° pattern LRP is at least as effective in achieving the surgical goal as the conventional (slit-lamp or indirect ophthalmoscope) approaches with a single-spot laser.
Laser beam-plasma plume interaction during laser welding
NASA Astrophysics Data System (ADS)
Hoffman, Jacek; Moscicki, Tomasz; Szymanski, Zygmunt
2003-10-01
Laser welding process is unstable because the keyhole wall performs oscillations which results in the oscillations of plasma plume over the keyhole mouth. The characteristic frequencies are equal to 0.5-4 kHz. Since plasma plume absorbs and refracts laser radiation, plasma oscillations modulate the laser beam before it reaches the workpiece. In this work temporary electron densities and temperatures are determined in the peaks of plasma bursts during welding with a continuous wave CO2 laser. It has been found that during strong bursts the plasma plume over the keyhole consists of metal vapour only, being not diluted by the shielding gas. As expected the values of electron density are about two times higher in peaks than their time-averaged values. Since the plasma absorption coefficient scales as ~N2e/T3/2 (for CO2 laser radiation) the results show that the power of the laser beam reaching the metal surface is modulated by the plasma plume oscillations. The attenuation factor equals 4-6% of the laser power but it is expected that it is doubled by the refraction effect. The results, together with the analysis of the colour pictures from streak camera, allow also interpretation of the dynamics of the plasma plume.
Research on the laser angle deception jamming technology of laser countermeasure
NASA Astrophysics Data System (ADS)
Ma, Shi-wei; Chen, Wen-jian; Gao, Wei; Duan, Yuan-yuan
2015-10-01
In recent years , laser guided weapons behave very well at destroying the military goals in the local wars, the single-shot probability, effective range and hitting precision getting better. And the semi-active laser guided weapons are the most widely used laser guided weapons. In order to improve the viability and protect important military goals, it's necessary to study the technology to against the semi-active guided weapons. This paper studies the working principle, the advantages and disadvantages of the semi-active guided weapons at first, and analyze the possibility of laser angle deception jamming system working. Then it analyzes the working principle and process of laser angle deception jamming technology. Finally it designs a half-real simulation system of laser angle deception jamming, which consists of semi-active laser guided weapons simulation system and laser angle deception jamming system. The simulation system demonstrates the working process of the laser angle deception jamming system. This paper provides fundamental base for the research on the countermeasure technology of semi-active laser guided weapons.
Fiber Based Seed Laser for CO 2 Ultrafast Laser Systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen, Yuchuan
A compact and effective 10-micron femtosecond laser with pulse duration <500fs and repetition rate of >100Hz or smaller is desirable by DOE for seeding CO 2 ultrafast laser systems to improve the stability, reliability and efficiency in generating 10-micron laser from GW up to 100TW peak power, which is irreplaceable in driving an accelerator for particle beam generation due to the efficiency proportional to the square of the laser wavelength. Agiltron proposes a fiber based ultrafast 10-micron seed laser that can provide the required specifications and high performance. Its success will directly benefit DOE’s compact proton and ion sources. Themore » innovative technology can be used for ultrafast laser generation over the whole mid-IR range, and speed up the development of mid-IR laser applications. Agiltron, Inc. has successfully completed all tasks and demonstrated the feasibility of a fiber based 10-micron ultrafast laser in Phase I of the Program. We built a mode-locked fiber laser that generated < 400fs ultrafast laser pulses and successfully controlled the repetition rate to be the required 100Hz. Using this mode-locked laser, we demonstrated the feasibility of parametric femtosecond laser generation based on frequency down conversion. The experimental results agree with our simulation results. The investigation results of Phase I will be used to optimize the design of the laser system and build a fully functional prototype for delivery to the DOE in the Phase II program. The prototype development in Phase II program will be in the collaboration with Professor Chandrashekhar Joshi, the leader of UCLA Laser-Plasma group. Prof. Joshi discovered a new mechanism for generation of monoenergetic proton/ion beams: Shock Wave Acceleration in a near critical density plasma and demonstrated that high-energy proton beams using CO 2 laser driven collisionless shocks in a gas jet plasma, which opened an opportunity to develop a rather compact high-repetition rate
Nd:GdVO4 ring laser pumped by laser diodes
NASA Astrophysics Data System (ADS)
Hao, E. J.; Li, T.; Wang, Z. D.; Zhang, Y.
2013-02-01
The design and operation of a laser diode-pumped Nd:GdVO4 ring laser is described. A composite crystal (Nd:GdVO4/YVO4) with undoped ends is single-end pumped by a fiber-coupled laser diode (LD) at 808 nm. A four-mirror ring cavity is designed to keep the laser operating unidirectionally, which eliminates spatial hole burning in the standing-wave cavity. This laser can operate either as continuous wave (CW) or Q-switched. The single-frequency power obtained was 9.1 W at 1063 nm. Q-switched operation produced 0.23 mJ/pulse at 20 kHz in the fundamental laser.
In-Flight Performance of the Mercury Laser Altimeter Laser Transmitter
NASA Technical Reports Server (NTRS)
Yu, Anthony W.; Sun, Xiaoli; Li, Steven X.; Cavanaugh, John F.; Neumann, Gregory A.
2014-01-01
The Mercury Laser Altimeter (MLA) is one of the payload instruments on the MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) spacecraft, which was launched on August 3, 2004. MLA maps Mercury's shape and topographic landforms and other surface characteristics using a diode-pumped solid-state laser transmitter and a silicon avalanche photodiode receiver that measures the round-trip time of individual laser pulses. The laser transmitter has been operating nominally during planetary flyby measurements and in orbit about Mercury since March 2011. In this paper, we review the MLA laser transmitter telemetry data and evaluate the performance of solid-state lasers under extended operation in a space environment.
NASA Astrophysics Data System (ADS)
Michaelis, M. M.; Forbes, A.; Bingham, R.; Kellett, B. J.; Mathye, A.
2008-05-01
A variety of laser applications in space, past, present, future and far future are reviewed together with the contributions of some of the scientists and engineers involved, especially those that happen to have South African connections. Historically, two of the earliest laser applications in space, were atmospheric LIDAR and lunar ranging. These applications involved atmospheric physicists, several astronauts and many of the staff recruited into the Soviet and North American lunar exploration programmes. There is a strong interest in South Africa in both LIDAR and lunar ranging. Shortly after the birth of the laser (and even just prior) theoretical work on photonic propulsion and space propulsion by laser ablation was initiated by Georgii Marx, Arthur Kantrowitz and Eugen Saenger. Present or near future experimental programs are developing in the following fields: laser ablation propulsion, possibly coupled with rail gun or gas gun propulsion; interplanetary laser transmission; laser altimetry; gravity wave detection by space based Michelson interferometry; the de-orbiting of space debris by high power lasers; atom laser interferometry in space. Far future applications of laser-photonic space-propulsion were also pioneered by Carl Sagan and Robert Forward. They envisaged means of putting Saenger's ideas into practice. Forward also invented a laser based method for manufacturing solid antimatter or SANTIM, well before the ongoing experiments at CERN with anti-hydrogen production and laser-trapping. SANTIM would be an ideal propellant for interstellar missions if it could be manufactured in sufficient quantities. It would be equally useful as a power source for the transmission of information over light year distances. We briefly mention military lasers. Last but not least, we address naturally occurring lasers in space and pose the question: "did the Big Bang lase?"
Information computer program for laser therapy and laser puncture
NASA Astrophysics Data System (ADS)
Badovets, Nadegda N.; Medvedev, Andrei V.
1995-03-01
An informative computer program containing laser therapy and puncture methods has been developed. It was used successfully in connection with the compact Russian medical laser apparatus HELIOS-O1M in laser treatment and the education process.
The pulsed dye laser versus the Q-switched Nd:YAG laser in laser-induced shock-wave lithotripsy.
Thomas, S; Pensel, J; Engelhardt, R; Meyer, W; Hofstetter, A G
1988-01-01
To date, there are two fairly well-established alternatives for laser-induced shock-wave lithotripsy in clinical practice. The Q-switched Nd:YAG laser is distinguished by the high-stone selectivity of its coupler systems. The necessity of a coupler system and its fairly small conversion rate of light energy into mechanical energy present serious drawbacks. Furthermore, the minimal outer diameter of the transmission system is 1.8 mm. The pulsed-dye laser can be used with a highly flexible and uncomplicated 200-micron fiber. However, the laser system itself is more complicated than the Q-switched Nd:YAG laser and requires a great deal of maintenance. Biological evaluation of damage caused by direct irradiation shows that both laser systems produce minor damage of different degrees. YAG laser lithotripsy with the optomechanical coupler was assessed in 31 patients with ureteral calculi. The instability and limited effectiveness of the fiber application system necessitated auxiliary lithotripsy methods in 14 cases. Dye-laser lithotripsy is currently being tested in clinical application. Further development, such as systems for blind application or electronic feedback mechanisms to limit adverse tissue effects, have yet to be optimized. Nevertheless, laser-induced shock-wave lithotripsy has the potential to become a standard procedure in the endourologic management of stone disease.
Pulsed-laser capabilities at the Laser-Hardened Materials Evaluation Laboratory (LHMEL)
NASA Astrophysics Data System (ADS)
Royse, Robert W.; Seibert, Daniel B., II; Lander, Michael L.; Eric, John J.
2000-08-01
Pulsed laser capabilities at the Laser Hardened Material Evaluation Laboratory are described relevant to optical coupling, impulse generation and laser propulsion. Capabilities of the Nd:Glass laser are presented as well as supporting test systems.
Effects of laser fluence on silicon modification by four-beam laser interference
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhao, Le; Li, Dayou; JR3CN and IRAC, University of Bedfordshire, Luton LU1 3JU
2015-12-21
This paper discusses the effects of laser fluence on silicon modification by four-beam laser interference. In this work, four-beam laser interference was used to pattern single crystal silicon wafers for the fabrication of surface structures, and the number of laser pulses was applied to the process in air. By controlling the parameters of laser irradiation, different shapes of silicon structures were fabricated. The results were obtained with the single laser fluence of 354 mJ/cm{sup 2}, 495 mJ/cm{sup 2}, and 637 mJ/cm{sup 2}, the pulse repetition rate of 10 Hz, the laser exposure pulses of 30, 100, and 300, the laser wavelength of 1064 nm, andmore » the pulse duration of 7–9 ns. The effects of the heat transfer and the radiation of laser interference plasma on silicon wafer surfaces were investigated. The equations of heat flow and radiation effects of laser plasma of interfering patterns in a four-beam laser interference distribution were proposed to describe their impacts on silicon wafer surfaces. The experimental results have shown that the laser fluence has to be properly selected for the fabrication of well-defined surface structures in a four-beam laser interference process. Laser interference patterns can directly fabricate different shape structures for their corresponding applications.« less
Laser safety research and modeling for high-energy laser systems
NASA Astrophysics Data System (ADS)
Smith, Peter A.; Montes de Oca, Cecilia I.; Kennedy, Paul K.; Keppler, Kenneth S.
2002-06-01
The Department of Defense has an increasing number of high-energy laser weapons programs with the potential to mature in the not too distant future. However, as laser systems with increasingly higher energies are developed, the difficulty of the laser safety problem increases proportionally, and presents unique safety challenges. The hazard distance for the direct beam can be in the order of thousands of miles, and radiation reflected from the target may also be hazardous over long distances. This paper details the Air Force Research Laboratory/Optical Radiation Branch (AFRL/HEDO) High-Energy Laser (HEL) safety program, which has been developed to support DOD HEL programs by providing critical capability and knowledge with respect to laser safety. The overall aim of the program is to develop and demonstrate technologies that permit safe testing, deployment and use of high-energy laser weapons. The program spans the range of applicable technologies, including evaluation of the biological effects of high-energy laser systems, development and validation of laser hazard assessment tools, and development of appropriate eye protection for those at risk.
Martin, John C.; Buican, Tudor N.
1989-01-01
Method and apparatus for sorting particles, such as biological particles. A first laser defines an optical path having an intensity gradient which is effective to propel the particles along the path but which is sufficiently weak that the particles are not trapped in an axial direction. A probe laser beam interrogates the particles to identify predetermined phenotypical characteristics of the particles. A second laser beam intersects the driving first laser beam, wherein the second laser beam is activated by an output signal indicative of a predetermined characteristic. The second laser beam is switchable between a first intensity and a second intensity, where the first intensity is effective to displace selected particles from the driving laser beam and the second intensity is effective to propel selected particles along the deflection laser beam. The selected particles may then be propelled by the deflection beam to a location effective for further analysis.
Optical radiation hazards of laser welding processes. Part II: CO2 laser.
Rockwell, R J; Moss, C E
1989-08-01
There has been an extensive growth within the last five years in the use of high-powered lasers in various metalworking processes. The two types of lasers used most frequently for laser welding/cutting processes are the Neodymium-yttrium-aluminum-garnet (Nd:YAG) and the carbon dioxide (CO2) systems. When such lasers are operated in an open beam configuration, they are designated as a Class IV laser system. Class IV lasers are high-powered lasers that may present an eye and skin hazard under most common exposure conditions, either directly or when the beam has been diffusely scattered. Significant control measures are required for unenclosed (open beam), Class IV laser systems since workers may be exposed to scattered or reflected beams during the operation, maintenance, and service of these lasers. In addition to ocular and/or skin exposure hazards, such lasers also may present a multitude of nonlaser beam occupational concerns. Radiant energy measurements are reported for both the scattered laser radiation and the plasma-related plume radiations released during typical high-powered CO2 laser-target interactions. In addition, the application of the nominal hazard zone (NHZ) and other control measures also are discussed with special emphasis on Class IV industrial CO2 laser systems.
Nalcaci, Ruhi; Cokakoglu, Serpil
2013-01-01
Many types of dental lasers are currently available that can be efficiently used for soft and hard tissue applications in the field of orthodontics. For achieving the desired effects in the target tissue, knowledge of laser characteristics such as power, wavelength and timing, is necessary. Laser therapy is advantageous because it often avoids bleeding, can be pain free, is non-invasive and is relatively quick. The high cost is its primary disadvantage. It is very important to take the necessary precautions to prevent possible tissue damage when using laser dental systems. Here, we reviewed the main types and characteristics of laser systems used in dental practice and discuss the applications of lasers in orthodontics, harmful effects and laser system safety. PMID:24966719
NASA Astrophysics Data System (ADS)
Bednyakova, Anastasia; Turitsyn, Sergei K.
2015-03-01
The key to generating stable optical pulses is mastery of nonlinear light dynamics in laser resonators. Modern techniques to control the buildup of laser pulses are based on nonlinear science and include classical solitons, dissipative solitons, parabolic pulses (similaritons) and various modifications and blending of these methods. Fiber lasers offer remarkable opportunities to apply one-dimensional nonlinear science models for the design and optimization of very practical laser systems. Here, we propose a new concept of a laser based on the adiabatic amplification of a soliton pulse in the cavity—the adiabatic soliton laser. The adiabatic change of the soliton parameters during evolution in the resonator relaxes the restriction on the pulse energy inherent in traditional soliton lasers. Theoretical analysis is confirmed by extensive numerical modeling.
Qualification of Laser Diode Arrays for Mercury Laser Altimeter
NASA Technical Reports Server (NTRS)
Stephen, Mark; Vasilyev, Aleksey; Schafer, John; Allan, Graham R.
2004-01-01
NASA's requirements for high reliability, high performance satellite laser instruments have driven the investigation of many critical components; specifically, 808 nm laser diode array (LDA) pump devices. Performance of Quasi-CW, High-power, laser diode arrays under extended use is presented. We report the optical power over several hundred million pulse operation and the effect of power cycling and temperature cycling of the laser diode arrays. Data on the initial characterization of the devices is also presented.
Laser-diode-pumped 1319-nm monolithic non-planar ring single-frequency laser
NASA Astrophysics Data System (ADS)
Wang, Qing; Gao, Chunqing; Zhao, Yan; Yang, Suhui; Wei, Guanghui; 2, Dongmei Hong
2003-10-01
Single-frequency 1319-nm laser was obtained by using a laser-diode-pumped monolithic Nd:YAG crystal with a non-planar ring oscillator (NPRO). When the NPRO laser was pumped by an 800-?m fiber coupled laser diode, the output power of the single-frequency 1319-nm laser was 220 mW, and the slope efficiency was 16%. With a 100-1m fiber coupled diode laser pumped, 99-mW single-frequency 1319-nm laser was obtained with a slope efficiency of 29%.
Early, James W.; Lester, Charles S.
2002-01-01
In the apparatus of the invention, a first excitation laser or other excitation light source capable of producing alternating beams of light having different wavelengths is used in tandem with one or more ignitor lasers to provide a compact, durable, engine deployable fuel ignition laser system. Reliable fuel ignition is provided over a wide range of fuel conditions by using the single remote excitation light source for pumping one or more small lasers located proximate to one or more fuel combustion zones with alternating wavelengths of light.
Two-color hybrid laser wakefield and direct laser accelerator
NASA Astrophysics Data System (ADS)
Zhang, Xi; Khudik, V.; Bernstein, A.; Downer, M.; Shvets, G.
2017-03-01
We propose and investigate the concept of two-color laser wakefield and direct acceleration (LWDA) scheme in the regime of moderate (10 TW scale) laser powers. The concept utilizes two unequal frequency laser pulses: the leading long-wavelength (λ0 = 0.8 µm) wakefield laser pulse driving a nonlinear plasma wake, and a trailing short-wavelength (λDLA = λ0/2) DLA laser pulse. The combination of the large electric field, yet small ponderomotive pressure of the DLA pulse is shown to be advantageous for producing a higher energy and larger charge electron beam compared with the single frequency LWDA. The sensitivity of the dual-frequency LWDA to synchronization time jitter is also reduced.
Four-Pass Coupler for Laser-Diode-Pumped Solid-State Laser
NASA Technical Reports Server (NTRS)
Coyle, Donald B.
2008-01-01
A four-pass optical coupler affords increased (in comparison with related prior two-pass optical couplers) utilization of light generated by a laser diode in side pumping of a solid-state laser slab. The original application for which this coupler was conceived involves a neodymium-doped yttrium aluminum garnet (Nd:YAG) crystal slab, which, when pumped by a row of laser diodes at a wavelength of 809 nm, lases at a wavelength of 1,064 nm. Heretofore, typically, a thin laser slab has been pumped in two passes, the second pass occurring by virtue of reflection of pump light from a highly reflective thin film on the side opposite the side through which the pump light enters. In two-pass pumping, a Nd:YAG slab having a thickness of 2 mm (which is typical) absorbs about 84 percent of the 809-nm pump light power, leaving about 16 percent of the pump light power to travel back toward the laser diodes. This unused power can cause localized heating of the laser diodes, thereby reducing their lifetimes. Moreover, if the slab is thinner than 2 mm, then even more unused power travels back toward the laser diodes. The four-pass optical coupler captures most of this unused pump light and sends it back to the laser slab for two more passes. As a result, the slab absorbs more pump light, as though it were twice as thick. The gain and laser cavity beam quality of a smaller laser slab in conjunction with this optical coupler can thus be made comparable to those of a larger two-pass-pumped laser slab.
Martin, J.C.; Buican, T.N.
1987-11-30
Method and apparatus are provided for sorting particles, such as biological particles. A first laser is used to define an optical path having an intensity gradient which is effective to propel the particles along the path but which is sufficiently weak that the particles are not trapped in an axial direction. A probe laser beam is provided for interrogating the particles to identify predetermined phenotypical characteristics of the particles. A second laser beam is provided to intersect the driving first laser beam, wherein the second laser beam is activated by an output signal indicative of a predetermined characteristic. The second laser beam is switchable between a first intensity and a second intensity, where the first intensity is effective to displace selected particles from the driving laser beam and the second intensity is effective to propel selected particles along the deflection laser beam. The selected particles may then be propelled by the deflection beam to a location effective for further analysis. 2 figs.
High power diode lasers for solid-state laser pumps
NASA Technical Reports Server (NTRS)
Linden, Kurt J.; Mcdonnell, Patrick N.
1994-01-01
The development and commercial application of high power diode laser arrays for use as solid-state laser pumps is described. Such solid-state laser pumps are significantly more efficient and reliable than conventional flash-lamps. This paper describes the design and fabrication of diode lasers emitting in the 780 - 900 nm spectral region, and discusses their performance and reliability. Typical measured performance parameters include electrical-to-optical power conversion efficiencies of 50 percent, narrow-band spectral emission of 2 to 3 nm FWHM, pulsed output power levels of 50 watts/bar with reliability values of over 2 billion shots to date (tests to be terminated after 10 billion shots), and reliable operation to pulse lengths of 1 ms. Pulse lengths up to 5 ms have been demonstrated at derated power levels, and CW performance at various power levels has been evaluated in a 'bar-in-groove' laser package. These high-power 1-cm stacked-bar arrays are now being manufactured for OEM use. Individual diode laser bars, ready for package-mounting by OEM customers, are being sold as commodity items. Commercial and medical applications of these laser arrays include solid-state laser pumping for metal-working, cutting, industrial measurement and control, ranging, wind-shear/atmospheric turbulence detection, X-ray generation, materials surface cleaning, microsurgery, ophthalmology, dermatology, and dental procedures.
An overview of the laser ranging method of space laser altimeter
NASA Astrophysics Data System (ADS)
Zhou, Hui; Chen, Yuwei; Hyyppä, Juha; Li, Song
2017-11-01
Space laser altimeter is an active remote sensing instrument to measure topographic map of Earth, Moon and planetary. The space laser altimeter determines the range between the instrument and laser footprint by measuring round trip time of laser pulse. The return pulse reflected from ground surface is gathered by the receiver of space laser altimeter, the pulsewidth and amplitude of which are changeable with the variability of the ground relief. Meantime, several kinds of noise overlapped on the return pulse signal affect its signal-to-noise ratio. To eliminate the influence of these factors that cause range walk and range uncertainty, the reliable laser ranging methods need to be implemented to obtain high-precision range results. Based on typical space laser altimeters in the past few decades, various ranging methods are expounded in detail according to the operational principle of instruments and timing method. By illustrating the concrete procedure of determining time of flight of laser pulse, this overview provides the comparison of the employed technologies in previous and undergoing research programs and prospect innovative technology for space laser altimeters in future.
NASA Astrophysics Data System (ADS)
Lipchak, A. I.; Solomonov, V. I.; Tel'nov, V. A.; Osipov, V. V.
1995-04-01
An experimental investigation was made of the spectral and temporal characteristics of a laser plasma formed by the interaction of a CO2 laser pulse with a target in atmospheric air. The results obtained indicate that the main role in the process of filling the excited states in a laser plasma is played by a recombination cascade and that both atoms and molecules of the atmospheric gases are excited. The result also show that a laser plasma can be used in spectroscopic analysis of multicomponent samples. The solution of the thermophysical problem of heating of a target by laser radiation supports the existing ideas on the process of formation of a plasma near the target surface in air.
Laser And Nonlinear Optical Materials For Laser Remote Sensing
NASA Technical Reports Server (NTRS)
Barnes, Norman P.
2005-01-01
NASA remote sensing missions involving laser systems and their economic impact are outlined. Potential remote sensing missions include: green house gasses, tropospheric winds, ozone, water vapor, and ice cap thickness. Systems to perform these measurements use lanthanide series lasers and nonlinear devices including second harmonic generators and parametric oscillators. Demands these missions place on the laser and nonlinear optical materials are discussed from a materials point of view. Methods of designing new laser and nonlinear optical materials to meet these demands are presented.
Publications - GMC 191 | Alaska Division of Geological & Geophysical
(3,489'-3,511') from the Union Oil Co. of California Ruby State #1 well Authors: Unknown Publication Date the Union Oil Co. of California Ruby State #1 well: Alaska Division of Geological & Geophysical
Backus, S.; Kapteyn, H.C.; Murnane, M.M.
1997-07-01
Laser amplifiers and methods for amplifying a laser beam are disclosed. A representative embodiment of the amplifier comprises first and second curved mirrors, a gain medium, a third mirror, and a mask. The gain medium is situated between the first and second curved mirrors at the focal point of each curved mirror. The first curved mirror directs and focuses a laser beam to pass through the gain medium to the second curved mirror which reflects and recollimates the laser beam. The gain medium amplifies and shapes the laser beam as the laser beam passes therethrough. The third mirror reflects the laser beam, reflected from the second curved mirror, so that the laser beam bypasses the gain medium and return to the first curved mirror, thereby completing a cycle of a ring traversed by the laser beam. The mask defines at least one beam-clipping aperture through which the laser beam passes during a cycle. The gain medium is pumped, preferably using a suitable pumping laser. The laser amplifier can be used to increase the energy of continuous-wave or, especially, pulsed laser beams including pulses of femtosecond duration and relatively high pulse rate. 7 figs.
Backus, Sterling; Kapteyn, Henry C.; Murnane, Margaret M.
1997-01-01
Laser amplifiers and methods for amplifying a laser beam are disclosed. A representative embodiment of the amplifier comprises first and second curved mirrors, a gain medium, a third mirror, and a mask. The gain medium is situated between the first and second curved mirrors at the focal point of each curved mirror. The first curved mirror directs and focuses a laser beam to pass through the gain medium to the second curved mirror which reflects and recollimates the laser beam. The gain medium amplifies and shapes the laser beam as the laser beam passes therethough. The third mirror reflects the laser beam, reflected from the second curved mirror, so that the laser beam bypasses the gain medium and return to the first curved mirror, thereby completing a cycle of a ring traversed by the laser beam. The mask defines at least one beam-clipping aperture through which the laser beam passes during a cycle. The gain medium is pumped, preferably using a suitable pumping laser. The laser amplifier can be used to increase the energy of continuous-wave or, especially, pulsed laser beams including pulses of femtosecond duration and relatively high pulse rate.
Barkana, Y; Belkin, M
2000-01-01
Laser instruments are used in many spheres of human activity, including medicine, industry, laboratory research, entertainment, and, notably, the military. This widespread use of lasers has resulted in many accidental injuries. Injuries are almost always retinal, because of the concentration of visible and near-infrared radiation on the retina. The retina is therefore the body tissue most vulnerable to laser radiation. The nature and severity of this type of retinal injury is determined by multiple laser-related and eye-related factors, the most important being the duration and amount of energy delivered and the retinal location of the lesion. The clinical course of significant retinal laser injuries is characterized by sudden loss of vision, often followed by marked improvement over a few weeks, and occasionally severe late complications. Medical and surgical treatment is limited. Laser devices hazardous to the human eye are currently in widespread use by armed forces. Furthermore, lasers may be employed specifically for visual incapacitation on future battlefields. Adherence to safety practices effectively prevents accidental laser-induced ocular injuries. However, there is no practical way to prevent injuries that are maliciously inflicted, as expected from laser weapons.
Design of diode-pumped solid-state laser applied in laser fuses
NASA Astrophysics Data System (ADS)
Deng, FangLin; Zhang, YiFei
2005-04-01
The function of laser fuzes which are parts of certain weapon systems is to control the blasting height of warheads. Commonly the battle environment these weapon systems are confronted with is very complicated and the tactical demand for them is very rigor, so laser fuzes equipped for them must fulfill some special technical requirements, such as high repetition rate, long ranging scope, etc. Lasers are one of key components which constitute fuze systems. Whether designed lasers are advanced and reasonable will determine whether laser fuzes can be applied in these weapon systems or not. So we adopt the novel technology of diode-pumped solid-state laser (DPSSL) to design lasers applied in fuzes. Nd:YVO4 crystal is accepted as gain material, which has wide absorption band and large absorption efficient for 808nm pumping laser. As warhead's temperature is usually very high, wider absorption band is beneficial to reduce the influence of temperature fluctuation. Passive Q-switching with Cr4+:YAG is used to reduce the power consumption farthest. Design the end-pumped microchip sandwich-architecture to decrease lasers' size and increase the reliability, further it's advantageous to produce short pulses and increase peak power of lasers. The designed DPSSL features small size and weight, high repetition rate and peak power, robustness, etc. The repetition rate is expected to reach 1 kHz; peak power will exceed 300 kW; pulse width is only 5 ns; and divergence angle of laser beams is less than 5 mrad. So DPSSL is suitable for laser fuzes as an emitter.
Only lasers can be used for low level laser therapy
Moskvin, Sergey Vladimirovich
2017-01-01
The question of lasers' exclusivity, as well as the degree of influence of special properties of low-intensity laser illumination (LILI), such as coherence, polarity and monochromaticity, on the effectiveness of low level laser therapy (LLLT) continues to cause arguments. The study analyzes publications from 1973 to 2016, in which laser and conventional light sources are compared, and the following conclusions are drawn. First, there are a lot of publications with incorrect comparison or unfounded statements. Secondly, other sources of light are often meant by LILI without any justification. Thirdly, all studies, in which the comparison is carried out correctly and close parameters of the impact and the model are used, have a firm conclusion that laser light is much more effective. Fourthly, it is uniquely identified that the most important parameter that determines the efficiency of lasers is monochromaticity, i.e., a much narrower spectral width than for all other light sources. Only laser light sources can be used for LLLT! PMID:29130447
NASA Astrophysics Data System (ADS)
1991-12-01
The major results of an experimental study of a slab Nd:YAG laser are reported in the article; the laser was successfully developed by the authors. The major findings include the following: (1) a method for cooling the blended flowing air and water, as well the related experimental parameters; (2) by using a crossed lens cavity, the authors further improved the anomalous capability within the compensation cavity of the slab laser, as well as higher insensitivity of the system to maladjustment; and (3) a processing technique and major points of slab YAG laser medium.
Comparison of four different lasers for acne scars: Resurfacing and fractional lasers.
You, Hi-Jin; Kim, Deok-Woo; Yoon, Eul-Sik; Park, Seung-Ha
2016-04-01
Acne scars are common and cause cosmetic problems. There is a multitude of treatment options for acne scars, including dermabrasion, chemical peeling, and fillers, but the advent of laser technology has greatly improved the treatment of acne scars. Although several laser systems are available, studies comparing their efficacy are limited. This study compares the results of treatments using resurfacing (carbon dioxide, CO2; erbium-doped yttrium aluminum garnet, Er:YAG) versus fractional (nonablative fractional laser, NAFL; ablative fractional laser, AFL) lasers. A retrospective photographic analysis of 58 patients who underwent laser treatment for facial atrophic acne scars was performed. Clinical improvement was assessed by six blinded investigators with a scale graded from 0 to 10. Adverse events were also noted. Mean improvement scores of the CO2, Er:YAG, NAFL, and AFL groups were 6.0, 5.8, 2.2, and 5.2, respectively. The NAFL group showed a significantly lower score than the other groups. The mean number of treatments was significantly greater in the fractional laser groups than in the resurfacing laser groups. The resurfacing laser groups had a prolonged recovery period and high risk of complications. The Er:YAG laser caused less erythema or pigmentation compared to the CO2 laser. Although the CO2 laser, Er:YAG laser, and AFL improved the acne scars, the CO2 laser had a greater downtime. Three consecutive AFL treatments are as effective as a single treatment with resurfacing lasers, with shorter social downtime periods and less adverse effects. Copyright © 2016 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
Design and Construction of Simple, Nitrogen-Laser-Pumped, Tunable Dye Lasers
ERIC Educational Resources Information Center
Hilborn, Robert C.
1978-01-01
The basic physical principles of dye lasers are discussed and used to analyze the design and operation of tunable dye lasers pumped by pulsed nitrogen lasers. Details of the design and construction of these dye lasers are presented. Some simple demonstration experiments are described. (BB)
... Cancer Treatment On This Page What is laser light? What is laser therapy, and how is it ... future hold for laser therapy? What is laser light? The term “ laser ” stands for light amplification by ...
Heterodyne laser spectroscopy system
Wyeth, Richard W.; Paisner, Jeffrey A.; Story, Thomas
1990-01-01
A heterodyne laser spectroscopy system utilizes laser heterodyne techniques for purposes of laser isotope separation spectroscopy, vapor diagnostics, processing of precise laser frequency offsets from a reference frequency, and provides spectral analysis of a laser beam.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, Shuo; Chen, Rongzhang; Nelsen, Bryan
2016-03-15
This paper reports the development of a compact and portable actively Q-switched Nd:YAG laser and its applications in laser-induced breakdown spectroscopy (LIBS). The laser was end-pumped by a vertical-cavity surface-emitting laser (VCSEL). The cavity lases at a wavelength of 1064 nm and produced pulses of 16 ns with a maximum pulse energy of 12.9 mJ. The laser exhibits a reliable performance in terms of pulse-to-pulse stability and timing jitter. The LIBS experiments were carried out using this laser on NIST standard alloy samples. Shot-to-shot LIBS signal stability, crater profile, time evolution of emission spectra, plasma electron density and temperature, andmore » limits of detection were studied and reported in this paper. The test results demonstrate that the VCSEL-pumped solid-state laser is an effective and compact laser tool for laser remote sensing applications.« less
Laser myringotomy with the CO2 Otoscan laser
NASA Astrophysics Data System (ADS)
Sedlmaier, Benedikt W.; Jivanjee, Antonio; Schoenfeld, Uwe; Jovanovic, Sergije
2000-06-01
Tympanic ventilation is the treatment of choice for otitis media with effusion (OME). CO2 laser myringotomy has already proven its value and is finding increasing clinical application. The ventilation time in the middle ear is essentially determined by the size of the laser perforation. Perforations exceeding 2 mm in diameter enable tympanic ventilation for about three weeks and thus compete with the ventilation tube in the treatment of OME. IN a prospective study, laser myringotomy is performed in 84 children with OME with the new CO2 laser otoscope Otoscan. The closure time was 17 days in average for a preformation diameter of 2 mm. In the further clinical course, the ear-drums healed without atrophic scar formation. In an observation period of six month the recurrency rate of effusion was approximately 10 percent. Laser myringotomy seems to be an useful method in the operative therapy of secretory otitis media.
2016-10-31
microchip laser : (top) schematic and (bottom) photograph of working device mounted on 12.7-mm- dia. post. switch 17 (355-nm UV ), 1.5 µJ of fourth......USA E-mail: zayhowski@ll.mit.edu Abstract Microchip lasers are a rich family of solid-state lasers defined by their small size, robust integration
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bohn, Willy L.
First, an introductory overview of the different types of laser propulsion techniques will be given and illustrated by some historical examples. Second, laser devices available for basic experiments will be reviewed ranging from low power lasers sources to inertial confinement laser facilities. Subsequently, a status of work will show the impasse in which the laser propulsion community is currently engaged. Revisiting the basic relations leads to new avenues in ablative and direct laser propulsion for ground based and space based applications. Hereby, special attention will be devoted to the impact of emerging ultra-short pulse lasers on the coupling coefficient andmore » specific impulse. In particular, laser sources and laser propulsion techniques will be tested in microgravity environment. A novel approach to debris removal will be discussed with respect to the Satellite Laser Ranging (SRL) facilities. Finally, some non technical issues will be raised aimed at the future prospects of laser propulsion in the international community.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
The open source Project Haystack initiative defines meta data and communication standards related to data from buildings and intelligent devices. The Project Haystack REST API defines standard formats and operations for exchanging Haystack tagged data over HTTP. The HaystackRuby gem wraps calls to this REST API to enable Ruby application to easily integrate data hosted on a Project Haystack compliant server. The HaystackRuby gem was developed at the National Renewable Energy Lab to support applications related to campus energy. We hope that this tool may be useful to others.
Scott, Jill R.; Tremblay, Paul L.
2008-08-19
A laser device includes a virtual source configured to aim laser energy that originates from a true source. The virtual source has a vertical rotational axis during vertical motion of the virtual source and the vertical axis passes through an exit point from which the laser energy emanates independent of virtual source position. The emanating laser energy is collinear with an orientation line. The laser device includes a virtual source manipulation mechanism that positions the virtual source. The manipulation mechanism has a center of lateral pivot approximately coincident with a lateral index and a center of vertical pivot approximately coincident with a vertical index. The vertical index and lateral index intersect at an index origin. The virtual source and manipulation mechanism auto align the orientation line through the index origin during virtual source motion.
Coherent laser radar at 2 microns using solid-state lasers
NASA Technical Reports Server (NTRS)
Henderson, Sammy W.; Suni, Paul J. M.; Hale, Charley P.; Hannon, Stephen M.; Magee, James R.; Bruns, Dale L.; Yuen, Eric H.
1993-01-01
Coherent laser radar systems using 2-micron Tm- and Tm, Ho-doped solid-state lasers are useful for the remote range-resolved measurement of atmospheric winds, aerosol backscatter, and DIAL measurements of atmospheric water vapor and CO2 concentrations. Recent measurements made with a 2-micron coherent laser radar system, advances in the laser technology, and atmospheric propagation effects on 2-micron coherent lidar performance are described.
Heterodyne laser spectroscopy system
Wyeth, Richard W.; Paisner, Jeffrey A.; Story, Thomas
1989-01-01
A heterodyne laser spectroscopy system utilizes laser heterodyne techniques for purposes of laser isotope separation spectroscopy, vapor diagnostics, processing of precise laser frequency offsets from a reference frequency and the like, and provides spectral analysis of a laser beam.
Laser Safety Evaluation of the MILES and Mini MILES Laser Emitting Components
DOE Office of Scientific and Technical Information (OSTI.GOV)
AUGUSTONI, ARNOLD L.
Laser safety evaluation and output emission measurements were performed (during October and November 2001) on SNL MILES and Mini MILES laser emitting components. The purpose, to verify that these components, not only meet the Class 1 (eye safe) laser hazard criteria of the CDRH Compliance Guide for Laser Products and 21 CFR 1040 Laser Product Performance Standard; but also meet the more stringent ANSI Std. z136.1-2000 Safe Use of Lasers conditions for Class 1 lasers that govern SNL laser operations. The results of these measurements confirmed that all of the Small Arms Laser Transmitters, as currently set (''as is''), meetmore » the Class 1 criteria. Several of the Mini MILES Small Arms Transmitters did not. These were modified and re-tested and now meet the Class 1 laser hazard criteria. All but one System Controllers (hand held and rifle stock) met class 1 criteria for single trigger pulls and all presented Class 3a laser hazard levels if the trigger is held (continuous emission) for more than 5 seconds on a single point target. All units were Class 3a for ''aided'' viewing. These units were modified and re-tested and now meet the Class 1 hazard criteria for both ''aided'' as well as ''unaided'' viewing. All the Claymore Mine laser emitters tested are laser hazard Class 1 for both ''aided'' as well as ''unaided'' viewing.« less
NASA Astrophysics Data System (ADS)
Yang, Weijian; Adair Gerke, Stephen; Wei Ng, Kar; Rao, Yi; Chase, Christopher; Chang-Hasnain, Connie J.
2015-09-01
Cavity optomechanics explores the interaction between optical field and mechanical motion. So far, this interaction has relied on the detuning between a passive optical resonator and an external pump laser. Here, we report a new scheme with mutual coupling between a mechanical oscillator supporting the mirror of a laser and the optical field generated by the laser itself. The optically active cavity greatly enhances the light-matter energy transfer. In this work, we use an electrically-pumped vertical-cavity surface-emitting laser (VCSEL) with an ultra-light-weight (130 pg) high-contrast-grating (HCG) mirror, whose reflectivity spectrum is designed to facilitate strong optomechanical coupling, to demonstrate optomechanically-induced regenerative oscillation of the laser optomechanical cavity. We observe >550 nm self-oscillation amplitude of the micromechanical oscillator, two to three orders of magnitude larger than typical, and correspondingly a 23 nm laser wavelength sweep. In addition to its immediate applications as a high-speed wavelength-swept source, this scheme also offers a new approach for integrated on-chip sensors.
ERIC Educational Resources Information Center
John, Phillip
1982-01-01
Selected infrared laser chemistry topics are discussed including carbon dioxide lasers, infrared quanta and molecules, laser-induced chemistry, structural isomerization (laser purification, sensitized reactions, and dielectric breakdown), and fundamental principles of laser isotope separation, focusing on uranium isotope separation. (JN)
Laser Safety and Hazardous Analysis for the ARES (Big Sky) Laser System
DOE Office of Scientific and Technical Information (OSTI.GOV)
AUGUSTONI, ARNOLD L.
A laser safety and hazard analysis was performed for the ARES laser system based on the 2000 version of the American National Standards Institute's (ANSI) Standard Z136.1,for Safe Use of Lasers and the 2000 version of the ANSI Standard Z136.6, for Safe Use of Lasers Outdoors. The ARES laser system is a Van/Truck based mobile platform, which is used to perform laser interaction experiments and tests at various national test sites.
Micro-scanning mirrors for high-power laser applications in laser surgery
NASA Astrophysics Data System (ADS)
Sandner, Thilo; Kimme, Simon; Grasshoff, Thomas; Todt, Ulrich; Graf, Alexander; Tulea, Cristian; Lenenbach, Achim; Schenk, Harald
2014-03-01
We present two novel micro scanning mirrors with large aperture and HR dielectric coatings suitable for high power laser applications in a miniaturized laser-surgical instrument for neurosurgery to cut skull tissue. An electrostatic driven 2D-raster scanning mirror with 5x7.1mm aperture is used for dynamic steering of a ps-laser beam of the laser cutting process. A second magnetic 2D-beam steering mirror enables a static beam correction of a hand guided laser instrument. Optimizations of a magnetic gimbal micro mirror with 6 mm x 8 mm mirror plate are presented; here static deflections of 3° were reached. Both MEMS devices were successfully tested with a high power ps-laser at 532nm up to 20W average laser power.
Optimal laser wavelength for efficient laser power converter operation over temperature
DOE Office of Scientific and Technical Information (OSTI.GOV)
Höhn, O., E-mail: oliver.hoehn@ise.fraunhofer.de; Walker, A. W.; Bett, A. W.
2016-06-13
A temperature dependent modeling study is conducted on a GaAs laser power converter to identify the optimal incident laser wavelength for optical power transmission. Furthermore, the respective temperature dependent maximal conversion efficiencies in the radiative limit as well as in a practically achievable limit are presented. The model is based on the transfer matrix method coupled to a two-diode model, and is calibrated to experimental data of a GaAs photovoltaic device over laser irradiance and temperature. Since the laser wavelength does not strongly influence the open circuit voltage of the laser power converter, the optimal laser wavelength is determined tomore » be in the range where the external quantum efficiency is maximal, but weighted by the photon flux of the laser.« less
NASA Technical Reports Server (NTRS)
Bufton, Jack L.; Harding, David J.; Ramos-Izquierdo, Luis
1993-01-01
Laser altimetry provides a high-resolution, high-accuracy method for measurement of the elevation and horizontal variability of Earth-surface topography. The basis of the measurement is the timing of the round-trip propagation of short-duration pulses of laser radiation between a spacecraft and the Earth's surface. Vertical resolution of the altimetry measurement is determined primarily by laser pulsewidth, surface-induced spreading in time of the reflected pulse, and the timing precision of the altimeter electronics. With conventional gain-switched pulses from solid-state lasers and sub-nsec resolution electronics, sub-meter vertical range resolution is possible from orbital attitudes of several hundred kilometers. Horizontal resolution is a function of laser beam footprint size at the surface and the spacing between successive laser pulses. Laser divergence angle and altimeter platform height above the surface determine the laser footprint size at the surface, while laser pulse repetition-rate, laser transmitter beam configuration, and altimeter platform velocity determine the space between successive laser pulses. Multiple laser transitters in a singlaltimeter instrument provide across-track and along-track coverage that can be used to construct a range image of the Earth's surface. Other aspects of the multi-beam laser altimeter are discussed.
Color vision deficits and laser eyewear protection for soft tissue laser applications.
Teichman, J M; Vassar, G J; Yates, J T; Angle, B N; Johnson, A J; Dirks, M S; Thompson, I M
1999-03-01
Laser safety considerations require urologists to wear laser eye protection. Laser eye protection devices block transmittance of specific light wavelengths and may distort color perception. We tested whether urologists risk color confusion when wearing laser eye protection devices for laser soft tissue applications. Subjects were tested with the Farnsworth-Munsell 100-Hue Test without (controls) and with laser eye protection devices for carbon dioxide, potassium titanyl phosphate (KTP), neodymium (Nd):YAG and holmium:YAG lasers. Color deficits were characterized by error scores, polar graphs, confusion angles, confusion index, scatter index and color axes. Laser eye protection device spectral transmittance was tested with spectrophotometry. Mean total error scores plus or minus standard deviation were 13+/-5 for controls, and 44+/-31 for carbon dioxide, 273+/-26 for KTP, 22+/-6 for Nd:YAG and 14+/-8 for holmium:YAG devices (p <0.001). The KTP laser eye protection polar graphs, and confusion and scatter indexes revealed moderate blue-yellow and red-green color confusion. Color axes indicated no significant deficits for controls, or carbon dioxide, Nd:YAG or holmium:YAG laser eye protection in any subject compared to blue-yellow color vision deficits in 8 of 8 tested with KTP laser eye protection (p <0.001). Spectrophotometry demonstrated that light was blocked with laser eye protection devices for carbon dioxide less than 380, holmium:YAG greater than 850, Nd:YAG less than 350 and greater than 950, and KTP less than 550 and greater than 750 nm. The laser eye protection device for KTP causes significant blue-yellow and red-green color confusion. Laser eye protection devices for carbon dioxide, holmium:YAG and Nd:YAG cause no significant color confusion compared to controls. The differences are explained by laser eye protection spectrophotometry characteristics and visual physiology.
Laser one-dimensional range profile and the laser two-dimensional range profile of cylinders
NASA Astrophysics Data System (ADS)
Gong, Yanjun; Wang, Mingjun; Gong, Lei
2015-10-01
Laser one-dimensional range profile, that is scattering power from pulse laser scattering of target, is a radar imaging technology. The laser two-dimensional range profile is two-dimensional scattering imaging of pulse laser of target. Laser one-dimensional range profile and laser two-dimensional range profile are called laser range profile(LRP). The laser range profile can reflect the characteristics of the target shape and surface material. These techniques were motivated by applications of laser radar to target discrimination in ballistic missile defense. The radar equation of pulse laser is given in this paper. This paper demonstrates the analytical model of laser range profile of cylinder based on the radar equation of the pulse laser. Simulations results of laser one-dimensional range profiles of some cylinders are given. Laser range profiles of cylinder, whose surface material with diffuse lambertian reflectance, is given in this paper. Laser range profiles of different pulse width of cylinder are given in this paper. The influences of geometric parameters, pulse width, attitude on the range profiles are analyzed.
NASA Technical Reports Server (NTRS)
Rines, Glen A. (Inventor); Moulton, Peter F. (Inventor); Harrison, James (Inventor)
1993-01-01
A wavelength-tunable, injection-seeded, dispersion-compensated, dispersively-pumped solid state laser includes a lasing medium; a highly reflective mirror; an output coupler; at least one isosceles Brewster prism oriented to the minimum deviation angle between the medium and the mirror for directing light of different wavelengths along different paths; means for varying the angle of the highly reflective mirror relative to the light from at least one Brewster angle for selecting a predetermined laser operating wavelength; a dispersion compensation apparatus associated with the lasing medium; a laser injection seeding port disposed between the dispersion compensation apparatus and one of the mirror and coupler and including a reflective surface at an acute non-Brewster angle to the laser beam for introducing a seed input; a dispersion compensation apparatus associated with the laser medium including opposite chirality optical elements; the lasing medium including a pump surface disposed at an acute angle to the laser beam to define a discrete path for the pumping laser beam separate from the pumped laser beam.
NASA Astrophysics Data System (ADS)
Shafeev, Georgii A.; Pimenov, S. M.; Lubnin, Evgenii N.; Smolin, A. A.; Konov, Vitalii I.; Laptev, V. A.
1995-02-01
An experimental investigation was made of laser activation of diamond surfaces (single crystals and polycrystalline diamond films) prior to electroless before catalytic deposition of metals from solutions. The activation was carried out by a copper vapour laser or a KrF excimer laser in two ways: decomposition of a thin film of palladium acetylacetonate and local laser stimulated modification of the diamond surface by laser evaporation. An ohmic contact (Cu or Ni) with an adhesive strength of 3 N mm-2 was formed and the spatial resolution achieved was 10 μm.
Stokowski, S.E.
1987-10-20
A laser medium is particularly useful in high average power solid state lasers. The laser medium includes a chromium dopant and preferably neodymium ions as codopant, and is primarily a gadolinium scandium gallium garnet, or an analog thereof. Divalent cations inhibit spiral morphology as large boules from which the laser medium is derived are grown, and a source of ions convertible between a trivalent state and a tetravalent state at a low ionization energy are in the laser medium to reduce an absorption coefficient at about one micron wavelength otherwise caused by the divalent cations. These divalent cations and convertible ions are dispersed in the laser medium. Preferred convertible ions are provided from titanium or cerium sources.
Stokowski, Stanley E.
1989-01-01
A laser medium is particularly useful in high average power solid state lasers. The laser medium includes a chormium dopant and preferably neodymium ions as codopant, and is primarily a gadolinium scandium gallium garnet, or an analog thereof. Divalent cations inhibit spiral morphology as large boules from which the laser medium is derived are grown, and a source of ions convertible between a trivalent state and a tetravalent state at a low ionization energy are in the laser medium to reduce an absorption coefficient at about one micron wavelength otherwise caused by the divalent cations. These divalent cations and convertible ions are dispersed in the laser medium. Preferred convertible ions are provided from titanium or cerium sources.
NASA Technical Reports Server (NTRS)
Dutta, S.
1983-01-01
Applications of laser-based processing techniques to solar cell metallization are discussed. Laser-assisted thermal or photolytic maskless deposition from organometallic vapors or solutions may provide a viable alternative to photovoltaic metallization systems currently in use. High power, defocused excimer lasers may be used in conjunction with masks as an alternative to direct laser writing to provide higher throughput. Repeated pulsing with excimer lasers may eliminate the need for secondary plating techniques for metal film buildup. A comparison between the thermal and photochemical deposition processes is made.
NASA Astrophysics Data System (ADS)
McLear, Mark
1996-04-01
Laser technology has significantly impacted our everyday life. Lasers are now used to correct your vision, clear your arteries, and are used in the manufacturing of such diverse products as automobiles, cigarettes, and computers. Lasers are no longer a research tool looking for an application. They are now an integral part of manufacturing. In the case of Class IV lasers, this explosion in laser applications has exposed thousands of individuals to potential safety hazards including eye damage. Specific protective eyewear designed to attenuate the energy of the laser beam below the maximum permissible exposure is required for Class 3B and Class IV lasers according to laser safety standards.
Jallo, George I; Kothbauer, Karl F; Epstein, Fred J
2002-07-01
Lasers are commonly understood as instruments that produce a freestanding light beam that can cut or vaporize tissue. In contrast, a contact laser is an instrument where the laser beam resides entirely within a coated sapphire crystal probe tip. The authors describe the use of the contact laser for a variety of intraspinal procedures. The probe is mounted on a curved handpiece and can be used in the same way as any microsurgical instrument. The laser energy is delivered only at the probe tip and only on contact of the tip with tissue. Different probe sizes and shapes allow for sharp cutting or tissue vaporization with minimal tissue penetration. We have used this laser in 95 operations for dysraphic conditions, and intradural (both intra- and extramedullary) spinal tumors. It was easy to use for the microsurgically trained neurosurgeon. It is safer than a freestanding, noncontact, laser beam. To lyse scar tissue, evaporate lipomatous tissue, perform a precise myelotomy, and dissect, cut and debulk firm and fibrous intradural spinal lesions this instrument is superior to microscissors, suction, or the ultrasonic aspirator. The contact laser is a useful microsurgical instrument for use in neurosurgery. It combines the advantages of lasers with those of microinstruments and avoids most shortcomings of both.
Hagelstein, P.L.
1984-06-25
A short wavelength laser is provided that is driven by conventional-laser pulses. A multiplicity of panels, mounted on substrates, are supported in two separated and alternately staggered facing and parallel arrays disposed along an approximately linear path. When the panels are illuminated by the conventional-laser pulses, single pass EUV or soft x-ray laser pulses are produced.
Laser processing with specially designed laser beam
NASA Astrophysics Data System (ADS)
Asratyan, A. A.; Bulychev, N. A.; Feofanov, I. N.; Kazaryan, M. A.; Krasovskii, V. I.; Lyabin, N. A.; Pogosyan, L. A.; Sachkov, V. I.; Zakharyan, R. A.
2016-04-01
The possibility of using laser systems to form beams with special spatial configurations has been studied. The laser systems applied had a self-conjugate cavity based on the elements of copper vapor lasers (LT-5Cu, LT-10Cu, LT-30Cu) with an average power of 5, 10, or 30 W. The active elements were pumped by current pulses of duration 80-100 ns. The duration of laser generation pulses was up to 25 ns. The generator unit included an unstable cavity, where one reflector was a special mirror with a reflecting coating. Various original optical schemes used were capable of exploring spatial configurations and energy characteristics of output laser beams in their interaction with micro- and nanoparticles fabricated from various materials. In these experiments, the beam dimensions of the obtained zones varied from 0.3 to 5 µm, which is comparable with the minimum permissible dimensions determined by the optical elements applied. This method is useful in transforming a large amount of information at the laser pulse repetition rate of 10-30 kHz. It was possible to realize the high-precision micromachining and microfabrication of microscale details by direct writing, cutting and drilling (with the cutting width and through-hole diameters ranging from 3 to 100 µm) and produce microscale, deep, intricate and narrow grooves on substrate surfaces of metals and nonmetal materials. This system is used for producing high-quality microscale details without moving the object under treatment. It can also be used for microcutting and microdrilling in a variety of metals such as molybdenum, copper and stainless steel, with a thickness of up to 300 µm, and in nonmetals such as silicon, sapphire and diamond with a thickness ranging from 10 µm to 1 mm with different thermal parameters and specially designed laser beam.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Berns, M.W.
These proceedings collect papers on laser biomedicine. Topics include: light distributions on tissue; chemical byproducts of laser/tissue interactions; laser applications in ophthalmology; phododynamic therapy; diode pumped solid state lasers at two and three micrometers; and applications of excimer lasers to peripheral nerve repair.
Practical application of pulsed "eye-safe" microchip laser to laser rangefinders
NASA Astrophysics Data System (ADS)
Młyńczak, J.; Kopczyński, K.; Mierczyk, Z.; Zygmunt, M.; Natkański, S.; Muzal, M.; Wojtanowski, J.; Kirwil, P.; Jakubaszek, M.; Knysak, P.; Piotrowski, W.; Zarzycka, A.; Gawlikowski, A.
2013-09-01
The paper describes practical application of pulsed microchip laser generating at 1535-nm wavelength to a laser rangefinder. The complete prototype of a laser rangefinder was built and investigated in real environmental conditions. The measured performance of the device is discussed. To build the prototype of a laser rangefinder at a reasonable price and shape a number of basic considerations had to be done. These include the mechanical and optical design of a microchip laser and the opto-mechanical construction of the rangefinder.
Only lasers can be used for low level laser therapy.
Moskvin, Sergey Vladimirovich
2017-12-01
The question of lasers' exclusivity, as well as the degree of influence of special properties of low-intensity laser illumination (LILI), such as coherence, polarity and monochromaticity, on the effectiveness of low level laser therapy (LLLT) continues to cause arguments. The study analyzes publications from 1973 to 2016, in which laser and conventional light sources are compared, and the following conclusions are drawn. First, there are a lot of publications with incorrect comparison or unfounded statements. Secondly, other sources of light are often meant by LILI without any justification. Thirdly, all studies, in which the comparison is carried out correctly and close parameters of the impact and the model are used, have a firm conclusion that laser light is much more effective. Fourthly, it is uniquely identified that the most important parameter that determines the efficiency of lasers is monochromaticity, i.e., a much narrower spectral width than for all other light sources. Only laser light sources can be used for LLLT! © Author(s) 2017. This article is published with open access by China Medical University.
Standoff analysis of laser-produced plasmas using laser-induced fluorescence
DOE Office of Scientific and Technical Information (OSTI.GOV)
Harilal, S. S.; Brumfield, B. E.; Phillips, M. C.
We report the use of laser-induced fluorescence (LIF) of laser ablation plumes for standoff applications. The standoff analysis of Al species, as major and minor species in samples, is performed in a nanosecond laser-produced plasma created at a distance ~10 m. The LIF analysis is performed by resonantly exciting an Al transition at 394.4 nm using a continuous wave (cw) tunable laser and by collecting the direct-line fluorescence signal at 396.15 nm. The spectral resolution of LIF is obtained by scanning the cw tunable LIF laser across the selected Al transition. Our results highlight that LIF provides enhanced signal intensity,more » emission persistence, and spectral resolution when compared to thermally-excited emission, and these are crucial considerations for using laser-produced plasma for standoff isotopic analysis.« less
Nilsen, Joseph
1991-01-01
An X-ray laser (10) that lases between the K edges of carbon and oxygen, i.e. between 44 and 23 Angstroms, is provided. The laser comprises a silicon (12) and dysprosium (14) foil combination (16) that is driven by two beams (18, 20) of intense line focused (22, 24) optical laser radiation. Ground state nickel-like dysprosium ions (34) are resonantly photo-pumped to their upper X-ray laser state by line emission from hydrogen-like silicon ions (32). The novel X-ray laser should prove especially useful for the microscopy of biological specimens.
Laser safety and hazard analysis for the temperature stabilized BSLT ARES laser system.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Augustoni, Arnold L.
A laser safety and hazard analysis was performed for the temperature stabilized Big Sky Laser Technology (BSLT) laser central to the ARES system based on the 2000 version of the American National Standards Institute's (ANSI) Standard Z136.1, for Safe Use of Lasers and the 2000 version of the ANSI Standard Z136.6, for Safe Use of Lasers Outdoors. As a result of temperature stabilization of the BSLT laser the operating parameters of the laser had changed requiring a hazard analysis based on the new operating conditions. The ARES laser system is a Van/Truck based mobile platform, which is used to performmore » laser interaction experiments and tests at various national test sites.« less
Kronenberg, Peter; Traxer, Olivier
2015-04-01
The purpose of the study was to review the existing literature on holmium:yttrium-aluminum-garnet laser lithotripsy regarding lithotripter settings and laser fibers. An online search of current and past peer-reviewed literature on holmium laser lithotripsy was performed on several databases, including PubMed, SciElo, and Google Scholar. Relevant studies and original articles about lithotripter settings and laser fibers were examined, and the most important information is summarized and presented here. We examine how the choice of lithotripter settings and laser fibers influences the performance of holmium laser lithotripsy. Traditional laser lithotripter settings are analyzed, including pulse energy, pulse frequency, and power levels, as well as newly developed long-pulse modes. The impact of these settings on ablation volume, fragment size, and retropulsion is also examined. Advantages of small- and large-diameter laser fibers are discussed, and controversies are highlighted. Additionally, the influence of the laser fiber is examined, specifically the fiber tip preparation and the lithotripter settings' influence on tip degradation. Many technical factors influence the performance of holmium laser lithotripsy. Knowing and understanding these controllable parameters allows the urologist to perform a laser lithotripsy procedure safely, efficiently, and with few complications.
Large laser projection displays utilizing all-solid-state RGB lasers
NASA Astrophysics Data System (ADS)
Xu, Zuyan; Bi, Yong
2005-01-01
RGB lasers projection displays have the advantages of producing large color triangle, high color saturation and high image resolution. In this report, with more than 4W white light synthesized by red (671nm), green (532nm) and blue (473nm) lasers, a RGB laser projection display system based on diode pumped solid-state lasers is developed and the performance of brilliant and vivid DVD dynamitic pictures on 60 inch screen is demonstrated.
NASA Technical Reports Server (NTRS)
Anthony, Thomas R. (Inventor)
1984-01-01
This invention provides a method for laser drilling small diameter, closely-spaced, and accurately located holes in a body of material which is transparent or substantially transparent to the laser radiation employed whereby the holes are drilled through the thickness of the body from the surface opposite to that on which the laser beam impinges to the surface of laser beam impingement.
NASA Technical Reports Server (NTRS)
1983-01-01
NASA-developed space shuttle technology is used in a laser wire stripper designed by Raytheon Company. Laser beams cut through insulation on a wire without damaging conductive metal, because laser radiation that melts plastic insulation is reflected by the metal. The laser process is fast, clean, precise and repeatable. It eliminates quality control problems and the expense of rejected wiring.
Heterodyne laser diagnostic system
Globig, Michael A.; Johnson, Michael A.; Wyeth, Richard W.
1990-01-01
The heterodyne laser diagnostic system includes, in one embodiment, an average power pulsed laser optical spectrum analyzer for determining the average power of the pulsed laser. In another embodiment, the system includes a pulsed laser instantaneous optical frequency measurement for determining the instantaneous optical frequency of the pulsed laser.
1992-09-01
This Guidance Article is an update of an article published in a special issue of Health Devices entitled "Lasers in Medicine--An Introduction" (13[8], June 1984). Although surgical lasers have a good overall safety record, they do expose patients, physicians, and other clinical staff to serious risks. Laser hazards can cause injury, disability, or even death: hospital staff have been burned by misdirected laser beams, technicians and maintenance personnel have received eye injuries while working on lasers and have been exposed to hazardous chemicals while changing laser dyes, and patients have died from injuries resulting from fires ignited by laser energy. Laser accidents most commonly result from misdirection of the laser beam. Direct or reflected radiation can burn skin, hair, or, more seriously, the cornea or retina, causing permanent damage. Misdirected laser energy can also cause ignition of surgical drapes, tracheal tubes, or the patient's hair. Also, a frequent by-product of laser-tissue interactions is laser plume, or smoke. Its acrid smell and particulate matter irritate the eyes, nose, and lungs and cause nausea; it is also a suspected vector for transmitting infectious materials, such as the human papilloma virus (HPV) associated with condyloma (a wartlike lesion) and cervical cancer. The risks are not limited to patients and those directly involved in using and maintaining lasers. Many laser procedures are performed in areas outside the controlled environment of the surgical suite; patients in a waiting area or even passersby could conceivably walk into an accessible laser treatment room, such as a doctor's office, and inadvertently be exposed to a direct or reflected beam.(ABSTRACT TRUNCATED AT 250 WORDS)
Salamu, Gabriela; Jipa, Florin; Zamfirescu, Marian; Pavel, Nicolaie
2014-03-10
We report on realization of buried waveguides in Nd:YAG ceramic media by direct femtosecond-laser writing technique and investigate the waveguides laser emission characteristics under the pump with fiber-coupled diode lasers. Laser pulses at 1.06 μm with energy of 2.8 mJ for the pump with pulses of 13.1-mJ energy and continuous-wave output power of 0.49 W with overall optical efficiency of 0.13 were obtained from a 100-μm diameter circular cladding waveguide realized in a 0.7-at.% Nd:YAG ceramic. A circular waveguide of 50-μm diameter yielded laser pulses at 1.3 μm with 1.2-mJ energy.
Laser Doppler velocimetry for continuous flow solar-pumped iodine laser system
NASA Technical Reports Server (NTRS)
Tabibi, Bagher M.; Lee, Ja H.
1991-01-01
A laser Doppler velocimetry (LDV) system was employed to measure the flow velocity profile of iodide vapor inside laser tubes of 36 mm ID and 20 mm ID. The LDV, which was operated in the forward scatter mode used a low power (15 mW) He-Ne laser beam. Velocity ranges from 1 m/s was measured to within one percent accuracy. The flow velocity profile across the laser tube was measured and the intensity of turbulence was determined. The flow of iodide inside the laser tube demonstrated a mixture of both turbulence and laminar flow. The flowmeter used for the laser system previously was calibrated with the LDV and found to be in good agreement.
Transversely bounded DFB lasers. [bounded distributed-feedback lasers
NASA Technical Reports Server (NTRS)
Elachi, C.; Evans, G.; Yeh, C.
1975-01-01
Bounded distributed-feedback (DFB) lasers are studied in detail. Threshold gain and field distribution for a number of configurations are derived and analyzed. More specifically, the thin-film guide, fiber, diffusion guide, and hollow channel with inhomogeneous-cladding DFB lasers are considered. Optimum points exist and must be used in DFB laser design. Different-modes feedback and the effects of the transverse boundaries are included. A number of applications are also discussed.
Effect of wavelength on cutaneous pigment using pulsed irradiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sherwood, K.A.; Murray, S.; Kurban, A.K.
Several reports have been published over the last two decades describing the successful removal of benign cutaneous pigmented lesions such as lentigines, cafe au lait macules' nevi, nevus of Ota, and lentigo maligna by a variety of lasers such as the excimer (351 nm), argon (488,514 nm), ruby (694 nm), Nd:YAG (1060 nm), and CO/sub 2/ (10,600 nm). Laser treatment has been applied to lesions with a range of pigment depths from superficial lentigines in the epidermis to the nevus of Ota in the reticular dermis. Widely divergent laser parameters of wavelength, pulse duration, energy density, and spotsizes have beenmore » used, but the laser parameters used to treat this range of lesions have been arbitrary, with little effort focused on defining optimal laser parameters for removal of each type. In this study, miniature black pig skin was exposed to five wavelengths (504, 590, 694, 720, and 750 nm) covering the absorption spectrum of melanin. At each wavelength, a range of energy densities was examined. Skin biopsies taken from laser-exposed sites were examined histologically in an attempt to establish whether optimal laser parameters exist for destroying pigment cells in skin. Of the five wavelengths examined, 504 nm produced the most pigment specific injury; this specificity being maintained even at the highest energy density of 7.0 J/cm2. Thus, for the destruction of melanin-containing cells in the epidermal compartment, 504 nm wavelength appears optimal.« less
Mathematical modeling of a photovoltaic-laser energy converter for iodine laser radiation
NASA Technical Reports Server (NTRS)
Walker, Gilbert H.; Heinbockel, John H.
1987-01-01
Space-based laser power systems will require converters to change laser radiation into electricity. Vertical junction photovoltaic converters are promising devices for this use. A promising laser for the laser power station is the t-C4F9I laser which emits radiation at a wavelength of 1.315 microns. This paper describes the results of mathematical modeling of a photovoltaic-laser energy converter for use with this laser. The material for this photovoltaic converter is Ga(53)In(47)As which has a bandgap energy of 0.94 eV, slightly below the energy of the laser photons (0.943 eV). Results of a study optimizing the converter parameters are presented. Calculated efficiency for a 1000 vertical junction converter is 42.5 percent at a power density of 1 x 10 to the 3d power w/sq cm.
NASA Astrophysics Data System (ADS)
Sentis, Marc L.; Delaporte, Philippe C.; Marine, Wladimir; Uteza, Olivier P.
2000-04-01
The application of excimer laser ablation process to the decontamination of radioactive surfaces is discussed. This technology is very attractive because it allows to efficiently remove the contaminated particles without secondary waste production. To demonstrate the capability of such technology to efficiently decontaminate large area, we studied and developed a prototype which include a XeCl laser, an optical fiber delivery system and an ablated particles collection cell. The main physical processes taking place during UV laser ablation will be explained. The influence of laser wavelength, pulse duration and absorption coefficient of material will be discussed. Special studies have been performed to understand the processes which limit the transmission of high average power excimer laser through optical fiber, and to determine the laser conditions to optimize the value of this transmission. An in-situ spectroscopic analysis of laser ablation plasma allows the real time control of the decontamination. The results obtained for painting or metallic oxides removal from stainless steel surfaces will be presented.
In space performance of the lunar orbiter laser altimeter (LOLA) laser transmitter
NASA Astrophysics Data System (ADS)
Yu, Anthony W.; Shaw, George B.; Novo-Gradac, Ann Marie; Li, Steven X.; Cavanaugh, John
2011-11-01
In this paper we present the final configuration of the space flight laser transmitter as delivered to the Lunar Orbiter Laser Altimeter (LOLA) instrument along with some in-space operation performance data. The LOLA instrument is designed to map the lunar surface and provide unprecedented data products in anticipation of future manned flight missions. The laser transmitter has been operating on orbit at the Moon continuously since July 2009 and accumulated over 1.8 billion laser shots in space. The LOLA laser transmitter design has heritage dated back to the MOLA laser transmitter launched more than 10 years ago and incorporates lessons learned from previous laser altimeter missions at NASA Goddard Space Flight Center.
The distribution of the scattered laser light in laser-plate-target coupling
NASA Astrophysics Data System (ADS)
Xiao-bo, Nie; Tie-qiang, Chang; Dong-xian, Lai; Shen-ye, Liu; Zhi-jian, Zheng
1997-04-01
Theoretical and experimental studies of the angular distributions of scattered laser light in laser-Au-plate-target coupling are reported. A simple model that describes three-dimensional plasmas and scattered laser light is presented. The approximate shape of critical density surface has been given and the three-dimensional laser ray tracing is applied in the model. The theoretical results of the model are consistent with the experimental data for the scattered laser light in the polar angle range of 25° to 145° from the laser beam.
Ultraviolet laser transverse profile shaping for improving x-ray free electron laser performance
Li, S.; Alverson, S.; Bohler, D.; ...
2017-08-17
The photocathode rf gun is one of the most critical components in x-ray free electron lasers. The drive laser strikes the photocathode surface, which emits electrons with properties that depend on the shape of the drive laser. Most free electron lasers use photocathodes with work function in the ultraviolet, a wavelength where direct laser manipulation becomes challenging. In this paper, we present a novel application of a digital micromirror device (DMD) for the 253 nm drive laser at the Linear Coherent Light Source. Laser profile shaping is accomplished through an iterative algorithm that takes into account shaping error and efficiency.more » Next, we use laser shaping to control the X-ray laser output via an online optimizer, which shows improvement in FEL pulse energy. Lastly, as a preparation for electron beam shaping, we use the DMD to measure the photocathode quantum efficiency across cathode surface with an averaged laser rms spot size of 59 μm. In conclusion, our experiments demonstrate promising outlook of using DMD to shape ultraviolet lasers for photocathode rf guns with various applications.« less
Ultraviolet laser transverse profile shaping for improving x-ray free electron laser performance
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, S.; Alverson, S.; Bohler, D.
The photocathode rf gun is one of the most critical components in x-ray free electron lasers. The drive laser strikes the photocathode surface, which emits electrons with properties that depend on the shape of the drive laser. Most free electron lasers use photocathodes with work function in the ultraviolet, a wavelength where direct laser manipulation becomes challenging. In this paper, we present a novel application of a digital micromirror device (DMD) for the 253 nm drive laser at the Linear Coherent Light Source. Laser profile shaping is accomplished through an iterative algorithm that takes into account shaping error and efficiency.more » Next, we use laser shaping to control the X-ray laser output via an online optimizer, which shows improvement in FEL pulse energy. Lastly, as a preparation for electron beam shaping, we use the DMD to measure the photocathode quantum efficiency across cathode surface with an averaged laser rms spot size of 59 μm. In conclusion, our experiments demonstrate promising outlook of using DMD to shape ultraviolet lasers for photocathode rf guns with various applications.« less
Ultraviolet laser transverse profile shaping for improving x-ray free electron laser performance
NASA Astrophysics Data System (ADS)
Li, S.; Alverson, S.; Bohler, D.; Egger, A.; Fry, A.; Gilevich, S.; Huang, Z.; Miahnahri, A.; Ratner, D.; Robinson, J.; Zhou, F.
2017-08-01
The photocathode rf gun is one of the most critical components in x-ray free electron lasers. The drive laser strikes the photocathode surface, which emits electrons with properties that depend on the shape of the drive laser. Most free electron lasers use photocathodes with work function in the ultraviolet, a wavelength where direct laser manipulation becomes challenging. In this paper, we present a novel application of a digital micromirror device (DMD) for the 253 nm drive laser at the Linear Coherent Light Source. Laser profile shaping is accomplished through an iterative algorithm that takes into account shaping error and efficiency. Next, we use laser shaping to control the X-ray laser output via an online optimizer, which shows improvement in FEL pulse energy. Lastly, as a preparation for electron beam shaping, we use the DMD to measure the photocathode quantum efficiency across cathode surface with an averaged laser rms spot size of 59 μ m . Our experiments demonstrate promising outlook of using DMD to shape ultraviolet lasers for photocathode rf guns with various applications.
NASA Technical Reports Server (NTRS)
Jalufka, N. W.
1989-01-01
The conversion of laser energy to other, more useful, forms is an important element of any space power transmission system employing lasers. In general the user, at the receiving sight, will require the energy in a form other than laser radiation. In particular, conversion to rocket power and electricity are considered to be two major areas where one must consider various conversion techniques. Three systems (photovoltaic cells, MHD generators, and gas turbines) have been identified as the laser-to-electricity conversion systems that appear to meet most of the criteria for a space-based system. The laser thruster also shows considerable promise as a space propulsion system. At this time one cannot predict which of the three laser-to-electric converters will be best suited to particular mission needs. All three systems have some particular advantages, as well as disadvantages. It would be prudent to continue research on all three systems, as well as the laser rocket thruster. Research on novel energy conversion systems, such as the optical rectenna and the reverse free-electron laser, should continue due to their potential for high payoff.
ERIC Educational Resources Information Center
Gibson, A. F.
1980-01-01
Discusses the present status and future prospects of laser-driven fusion. Current research (which is classified under three main headings: laser-matter interaction processes, compression, and laser development) is also presented. (HM)
Laser-driven plasma photonic crystals for high-power lasers
NASA Astrophysics Data System (ADS)
Lehmann, G.; Spatschek, K. H.
2017-05-01
Laser-driven plasma density gratings in underdense plasma are shown to act as photonic crystals for high power lasers. The gratings are created by counterpropagating laser beams that trap electrons, followed by ballistic ion motion. This leads to strong periodic plasma density modulations with a lifetime on the order of picoseconds. The grating structure is interpreted as a plasma photonic crystal time-dependent property, e.g., the photonic band gap width. In Maxwell-Vlasov and particle-in-cell simulations it is demonstrated that the photonic crystals may act as a frequency filter and mirror for ultra-short high-power laser pulses.
Laser demonstration and performance characterization of optically pumped Alkali Laser systems
NASA Astrophysics Data System (ADS)
Sulham, Clifford V.
Diode Pumped Alkali Lasers (DPALs) offer a promising approach for high power lasers in military applications that will not suffer from the long logistical trails of chemical lasers or the thermal management issues of diode pumped solid state lasers. This research focuses on characterizing a DPAL-type system to gain a better understanding of using this type of laser as a directed energy weapon. A rubidium laser operating at 795 nm is optically pumped by a pulsed titanium sapphire laser to investigate the dynamics of DPALs at pump intensities between 1.3 and 45 kW/cm2. Linear scaling as high as 32 times threshold is observed, with no evidence of second order kinetics. Comparison of laser characteristics with a quasi-two level analytic model suggests performance near the ideal steady-state limit, disregarding the mode mis-match. Additionally, the peak power scales linearly as high as 1 kW, suggesting aperture scaling to a few cm2 is sufficient to achieve tactical level laser powers. The temporal dynamics of the 100 ns pump and rubidium laser pulses are presented, and the continually evolving laser efficiency provides insight into the bottlenecking of the rubidium atoms in the 2P3/2 state. Lastly, multiple excited states of rubidium and cesium were accessed through two photon absorption in the red, yielding a blue and an IR photon through amplified stimulated emission. Threshold is modest at 0.3 mJ/pulse, and slope efficiencies increase dramatically with alkali concentrations and peak at 0.4%, with considerable opportunity for improvement. This versatile system might find applications for IR countermeasures or underwater communications.
Kozak, Igor; Luttrull, Jeffrey K.
2014-01-01
Medicinal lasers are a standard source of light to produce retinal tissue photocoagulation to treat retinovascular disease. The Diabetic Retinopathy Study and the Early Treatment Diabetic Retinopathy Study were large randomized clinical trials that have shown beneficial effect of retinal laser photocoagulation in diabetic retinopathy and have dictated the standard of care for decades. However, current treatment protocols undergo modifications. Types of lasers used in treatment of retinal diseases include argon, diode, dye and multicolor lasers, micropulse lasers and lasers for photodynamic therapy. Delivery systems include contact lens slit-lamp laser delivery, indirect ophthalmocope based laser photocoagulation and camera based navigated retinal photocoagulation with retinal eye-tracking. Selective targeted photocoagulation could be a future alternative to panretinal photocoagulation. PMID:25892934
Laser-Material Interaction of Powerful Ultrashort Laser Pulses
DOE Office of Scientific and Technical Information (OSTI.GOV)
Komashko, A
2003-01-06
Laser-material interaction of powerful (up to a terawatt) ultrashort (several picoseconds or shorter) laser pulses and laser-induced effects were investigated theoretically in this dissertation. Since the ultrashort laser pulse (USLP) duration time is much smaller than the characteristic time of the hydrodynamic expansion and thermal diffusion, the interaction occurs at a solid-like material density with most of the light energy absorbed in a thin surface layer. Powerful USLP creates hot, high-pressure plasma, which is quickly ejected without significant energy diffusion into the bulk of the material, Thus collateral damage is reduced. These and other features make USLPs attractive for amore » variety of applications. The purpose of this dissertation was development of the physical models and numerical tools for improvement of our understanding of the process and as an aid in optimization of the USLP applications. The study is concentrated on two types of materials - simple metals (materials like aluminum or copper) and wide-bandgap dielectrics (fused silica, water). First, key physical phenomena of the ultrashort light interaction with metals and the models needed to describe it are presented. Then, employing one-dimensional plasma hydrodynamics code enhanced with models for laser energy deposition and material properties at low and moderate temperatures, light absorption was self-consistently simulated as a function of laser wavelength, pulse energy and length, angle of incidence and polarization. Next, material response on time scales much longer than the pulse duration was studied using the hydrocode and analytical models. These studies include examination of evolution of the pressure pulses, effects of the shock waves, material ablation and removal and three-dimensional dynamics of the ablation plume. Investigation of the interaction with wide-bandgap dielectrics was stimulated by the experimental studies of the USLP surface ablation of water (water is a
Laser-Tissue Interaction in Tattoo Removal by Q-Switched Lasers
Barua, Shyamanta
2015-01-01
Q-switched (QS) lasers are widely considered the gold standard for tattoo removal, with excellent clinical results, impressive predictability, and a good safety profile. The generation of giant pulses by the method of Q-switching is responsible for the unique laser-tissue interaction that is seen in tattoo removal by QS lasers. The QS lasers work by impaction and dissolution of the tattoo pigments. Mechanical fragmentation of the tattoo pigments encased in intracellular lamellated organelles followed by their phagocytosis by macrophages is thought to be the major event in the clearance of pigments by QS lasers. A few novel techniques have been tried in recent times to hasten the clearance of tattoo pigments. PMID:25949016
Laser-tissue interaction in tattoo removal by q-switched lasers.
Barua, Shyamanta
2015-01-01
Q-switched (QS) lasers are widely considered the gold standard for tattoo removal, with excellent clinical results, impressive predictability, and a good safety profile. The generation of giant pulses by the method of Q-switching is responsible for the unique laser-tissue interaction that is seen in tattoo removal by QS lasers. The QS lasers work by impaction and dissolution of the tattoo pigments. Mechanical fragmentation of the tattoo pigments encased in intracellular lamellated organelles followed by their phagocytosis by macrophages is thought to be the major event in the clearance of pigments by QS lasers. A few novel techniques have been tried in recent times to hasten the clearance of tattoo pigments.
McKenzie, A L
1984-01-01
As the sales of surgical lasers continue to grow, the problem of laser safety in hospitals becomes increasingly more urgent. This article considers both the principles and the practice of laser safety, and indicates how safety codes should be organized within a hospital. Eye safety is of paramount importance, and the effects of different wavelengths of laser radiation on the eye are described, both for intrabeam and extended-source exposure. An account is given of the concept of Maximum Permissible Exposure (MPE) and how it depends upon wavelength and exposure duration. The standard laser classification is developed in relation to MPE. The use of laser protective eyewear is discussed for the surgeon, other theatre staff and the patient. Finally, the role of the Laser Protection Supervisor and of the Laser Protection Adviser are explained in the context of establishing a local laser safety code.
Sher, Mark H.; Macklin, John J.; Harris, Stephen E.
1989-09-26
A traveling-wave, laser-produced-plasma, energy source used to obtain single-pass gain saturation of a photoionization pumped laser. A cylindrical lens is used to focus a pump laser beam to a long line on a target. Grooves are cut in the target to present a surface near normal to the incident beam and to reduce the area, and hence increase the intensity and efficiency, of plasma formation.
5W intracavity frequency-doubled green laser for laser projection
NASA Astrophysics Data System (ADS)
Yan, Boxia; Bi, Yong; Li, Shu; Wang, Dongdong; Wang, Dongzhou; Qi, Yan; Fang, Tao
2014-11-01
High power green laser has many applications such as high brightness laser projection and large screen laser theater. A compact and high power green-light source has been developed in diode-pumped solid-state laser based on MgO doped periodically poled LiNbO3 (MgO:PPLN). 5W fiber coupled green laser is achieved by dual path Nd:YVO4/MgO:PPLN intra-cacity frequency-doubled. Single green laser maximum power 2.8W at 532nm is obtained by a 5.5W LD pumped, MgO:PPLN dimensions is 5mm(width)×1mm(thickness)×2mm(length), and the optical to optical conversion efficiency is 51%. The second LD series connected with the one LD, the second path green laser is obtained using the same method. Then the second path light overlap with the first path by the reflection mirrors, then couple into the fiber with a focus mirror. Dual of LD, Nd:YVO4, MgO:PPLN are placed on the same heat sink using a TEC cooling, the operating temperature bandwidth is about 12°C and the stablity is 5% in 96h. A 50×50×17mm3 laser module which generated continuous-wave 5 W green light with high efficiency and width temperature range is demonstrated.
Laser chirp effect on femtosecond laser filamentation generated for pulse compression.
Park, Juyun; Lee, Jae-Hwan; Nam, Chang H
2008-03-31
The influence of laser chirp on the formation of femtosecond laser filamentation in Ar was investigated for the generation of few-cycle high-power laser pulses. The condition for the formation of a single filament has been carefully examined using 28-fs laser pulses with energy over 3 mJ. The filament formation and output spectrum changed very sensitively to the initial laser chirp and gas pressure. Much larger spectral broadening was obtained with positively chirped pulses, compared to the case of negatively chirped pulses that generated much longer filament, and compressed pulses of 5.5 fs with energy of 0.5 mJ were obtained from the filamentation of positively chirped 30-fs laser pulses in a single Ar cell.
High-speed micro-scale laser shock peening using a fiber laser (Conference Presentation)
NASA Astrophysics Data System (ADS)
Zhang, Chenfei; Deng, Leimin; Sun, Shiding; Lu, Yongfeng
2017-03-01
Laser shock peening using low-energy nanosecond (ns) fiber lasers was investigated in this study to realize high-speed micro-scale laser shock peening on selected positions without causing surface damage. Due to the employment of a fiber laser with high-frequency and prominent environmental adaptability, the laser peening system is able to work with a much higher speed compared to traditional peening systems using Nd:YAG lasers and is promising for in-situ applications in harsh environments. Detailed surface morphology investigations both on sacrificial coatings and Al alloy surfaces after the fiber laser peening revealed the effects of focal position, pulse duration, peak power density, and impact times. Micro-dent arrays were also obtained with different spot-to-spot distances. Obvious micro-hardness improvement was observed inside the laser-peening-induced microdents after the fiber laser shock peening.
Transition-metal doped sulfide, selenide, and telluride laser crystal and lasers
Krupke, W.F.; Page, R.H.; DeLoach, L.D.; Payne, S.A.
1996-07-30
A new class of solid state laser crystals and lasers are formed of transition metal doped sulfide, selenide, and telluride host crystals which have four fold coordinated substitutional sites. The host crystals include II-VI compounds. The host crystal is doped with a transition metal laser ion, e.g., chromium, cobalt or iron. In particular, Cr{sup 2+}-doped ZnS and ZnSe generate laser action near 2.3 {micro}m. Oxide, chloride, fluoride, bromide and iodide crystals with similar structures can also be used. Important aspects of these laser materials are the tetrahedral site symmetry of the host crystal, low excited state absorption losses and high luminescence efficiency, and the d{sup 4} and d{sup 6} electronic configurations of the transition metal ions. The same materials are also useful as saturable absorbers for passive Q-switching applications. The laser materials can be used as gain media in amplifiers and oscillators; these gain media can be incorporated into waveguides and semiconductor lasers. 18 figs.
Transition-metal doped sulfide, selenide, and telluride laser crystal and lasers
Krupke, William F.; Page, Ralph H.; DeLoach, Laura D.; Payne, Stephen A.
1996-01-01
A new class of solid state laser crystals and lasers are formed of transition metal doped sulfide, selenide, and telluride host crystals which have four fold coordinated substitutional sites. The host crystals include II-VI compounds. The host crystal is doped with a transition metal laser ion, e.g., chromium, cobalt or iron. In particular, Cr.sup.2+ -doped ZnS and ZnSe generate laser action near 2.3 .mu.m. Oxide, chloride, fluoride, bromide and iodide crystals with similar structures can also be used. Important aspects of these laser materials are the tetrahedral site symmetry of the host crystal, low excited state absorption losses and high luminescence efficiency, and the d.sup.4 and d.sup.6 electronic configurations of the transition metal ions. The same materials are also useful as saturable absorbers for passive Q-switching applications. The laser materials can be used as gain media in amplifiers and oscillators; these gain media can be incorporated into waveguides and semiconductor lasers.
A laser is used for many medical purposes. Because the laser beam is so small and precise, it enables ... without injuring surrounding tissue. Some uses of the laser are retinal surgery, excision of lesions, and cauterization ...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dougherty, Thomas J
A workpiece cutting apparatus includes a laser source, a first suction system, and a first finger configured to guide a workpiece as it moves past the laser source. The first finger includes a first end provided adjacent a point where a laser from the laser source cuts the workpiece, and the first end of the first finger includes an aperture in fluid communication with the first suction system.
Weil, Bradley S.; Wetherington, Jr., Grady R.
1985-01-01
Laser beam monitoring systems include laser-transparent plates set at an angle to the laser beam passing therethrough and light sensor for detecting light reflected from an object on which the laser beam impinges.
Weil, B.S.; Wetherington, G.R. Jr.
Laser beam monitoring systems include laser-transparent plates set at an angle to the laser beam passing therethrough and light sensor for detecting light reflected from an object on which the laser beam impinges.
On-Chip Laser-Power Delivery System for Dielectric Laser Accelerators
NASA Astrophysics Data System (ADS)
Hughes, Tyler W.; Tan, Si; Zhao, Zhexin; Sapra, Neil V.; Leedle, Kenneth J.; Deng, Huiyang; Miao, Yu; Black, Dylan S.; Solgaard, Olav; Harris, James S.; Vuckovic, Jelena; Byer, Robert L.; Fan, Shanhui; England, R. Joel; Lee, Yun Jo; Qi, Minghao
2018-05-01
We propose an on-chip optical-power delivery system for dielectric laser accelerators based on a fractal "tree-network" dielectric waveguide geometry. This system replaces experimentally demanding free-space manipulations of the driving laser beam with chip-integrated techniques based on precise nanofabrication, enabling access to orders-of-magnitude increases in the interaction length and total energy gain for these miniature accelerators. Based on computational modeling, in the relativistic regime, our laser delivery system is estimated to provide 21 keV of energy gain over an acceleration length of 192 μ m with a single laser input, corresponding to a 108-MV/m acceleration gradient. The system may achieve 1 MeV of energy gain over a distance of less than 1 cm by sequentially illuminating 49 identical structures. These findings are verified by detailed numerical simulation and modeling of the subcomponents, and we provide a discussion of the main constraints, challenges, and relevant parameters with regard to on-chip laser coupling for dielectric laser accelerators.
Laser beam temporal and spatial tailoring for laser shock processing
Hackel, Lloyd; Dane, C. Brent
2001-01-01
Techniques are provided for formatting laser pulse spatial shape and for effectively and efficiently delivering the laser energy to a work surface in the laser shock process. An appropriately formatted pulse helps to eliminate breakdown and generate uniform shocks. The invention uses a high power laser technology capable of meeting the laser requirements for a high throughput process, that is, a laser which can treat many square centimeters of surface area per second. The shock process has a broad range of applications, especially in the aerospace industry, where treating parts to reduce or eliminate corrosion failure is very important. The invention may be used for treating metal components to improve strength and corrosion resistance. The invention has a broad range of applications for parts that are currently shot peened and/or require peening by means other than shot peening. Major applications for the invention are in the automotive and aerospace industries for components such as turbine blades, compressor components, gears, etc.
Design of micro-second pulsed laser mode for ophthalmological CW self-raman laser
NASA Astrophysics Data System (ADS)
Mota, Alessandro D.; Rossi, Giuliano; Ortega, Tiago A.; Costal, Glauco Z.; Fontes, Yuri C.; Yasuoka, Fatima M. M.; Stefani, Mario A.; de Castro N., Jarbas C.; Paiva, Maria S. V.
2011-02-01
This work presents the mechanisms adopted for the design of micro-second pulsed laser mode for a CW Self-Raman laser cavity in 586nm and 4W output power. The new technique for retina disease treatment discharges laser pulses on the retina tissue, in laser sequences of 200 μs pulse duration at each 2ms. This operation mode requires the laser to discharge fast electric pulses, making the system control velocity of the electronic system cavity vital. The control procedures to keep the laser output power stable and the laser head behavior in micro-second pulse mode are presented.
Nanocrystal waveguide (NOW) laser
Simpson, John T.; Simpson, Marcus L.; Withrow, Stephen P.; White, Clark W.; Jaiswal, Supriya L.
2005-02-08
A solid state laser includes an optical waveguide and a laser cavity including at least one subwavelength mirror disposed in or on the optical waveguide. A plurality of photoluminescent nanocrystals are disposed in the laser cavity. The reflective subwavelength mirror can be a pair of subwavelength resonant gratings (SWG), a pair of photonic crystal structures (PC), or a distributed feedback structure. In the case of a pair of mirrors, a PC which is substantially transmissive at an operating wavelength of the laser can be disposed in the laser cavity between the subwavelength mirrors to improve the mode structure, coherence and overall efficiency of the laser. A method for forming a solid state laser includes the steps of providing an optical waveguide, creating a laser cavity in the optical waveguide by disposing at least one subwavelength mirror on or in the waveguide, and positioning a plurality of photoluminescent nanocrystals in the laser cavity.
ERIC Educational Resources Information Center
Hill, P. D.
1989-01-01
Described are the characteristics of the laser and its effects on the body. Discussed are examples of laser treatments, including angioplasty, ophthalmology, and dermatology. A discussion of lasers of clinical interest and their applications is presented. (YP)
EDITORIAL: Laser and plasma accelerators Laser and plasma accelerators
NASA Astrophysics Data System (ADS)
Bingham, Robert
2009-02-01
This special issue on laser and plasma accelerators illustrates the rapid advancement and diverse applications of laser and plasma accelerators. Plasma is an attractive medium for particle acceleration because of the high electric field it can sustain, with studies of acceleration processes remaining one of the most important areas of research in both laboratory and astrophysical plasmas. The rapid advance in laser and accelerator technology has led to the development of terawatt and petawatt laser systems with ultra-high intensities and short sub-picosecond pulses, which are used to generate wakefields in plasma. Recent successes include the demonstration by several groups in 2004 of quasi-monoenergetic electron beams by wakefields in the bubble regime with the GeV energy barrier being reached in 2006, and the energy doubling of the SLAC high-energy electron beam from 42 to 85 GeV. The electron beams generated by the laser plasma driven wakefields have good spatial quality with energies ranging from MeV to GeV. A unique feature is that they are ultra-short bunches with simulations showing that they can be as short as a few femtoseconds with low-energy spread, making these beams ideal for a variety of applications ranging from novel high-brightness radiation sources for medicine, material science and ultrafast time-resolved radiobiology or chemistry. Laser driven ion acceleration experiments have also made significant advances over the last few years with applications in laser fusion, nuclear physics and medicine. Attention is focused on the possibility of producing quasi-mono-energetic ions with energies ranging from hundreds of MeV to GeV per nucleon. New acceleration mechanisms are being studied, including ion acceleration from ultra-thin foils and direct laser acceleration. The application of wakefields or beat waves in other areas of science such as astrophysics and particle physics is beginning to take off, such as the study of cosmic accelerators considered
Holographic studies of shock waves within transonic fan rotors
NASA Technical Reports Server (NTRS)
Benser, W. A.; Bailey, E. E.; Gelder, T. F.
1974-01-01
NASA has funded two separate contracts to apply pulsed laser holographic interferometry to the detection of shock patterns in the outer span regions of high tip speed transonic rotors. The first holographic approach used ruby laser light reflected from a portion of the centerbody just ahead of the rotor. These holograms showed the bow wave patterns upstream of the rotor and the shock patterns just inside the blade row near the tip. The second holographic approach, on a different rotor, used light transmitted diagonally across the inlet annulus past the centerbody. This approach gave a more extensive view of the region bounded by the blade leading and trailing edges, by the part span shroud and by the blade tip. These holograms showed the passage shock emanating from the blade leading edge and a moderately strong conical shock originating at the intersection of the part span shroud leading edge and the blade suction surface.
Laser rods with undoped, flanged end-caps for end-pumped laser applications
Meissner, Helmuth E.; Beach, Raymond J.; Bibeau, Camille; Sutton, Steven B.; Mitchell, Scott; Bass, Isaac; Honea, Eric
1999-01-01
A method and apparatus for achieving improved performance in a solid state laser is provided. A flanged, at least partially undoped end-cap is attached to at least one end of a laserable medium. Preferably flanged, undoped end-caps are attached to both ends of the laserable medium. Due to the low scatter requirements for the interface between the end-caps and the laser rod, a non-adhesive method of bonding is utilized such as optical contacting combined with a subsequent heat treatment of the optically contacted composite. The non-bonded end surfaces of the flanged end-caps are coated with laser cavity coatings appropriate for the lasing wavelength of the laser rod. A cooling jacket, sealably coupled to the flanged end-caps, surrounds the entire length of the laserable medium. Radiation from a pump source is focussed by a lens duct and passed through at least one flanged end-cap into the laser rod.
Laser rods with undoped, flanged end-caps for end-pumped laser applications
Meissner, H.E.; Beach, R.J.; Bibeau, C.; Sutton, S.B.; Mitchell, S.; Bass, I.; Honea, E.
1999-08-10
A method and apparatus for achieving improved performance in a solid state laser is provided. A flanged, at least partially undoped end-cap is attached to at least one end of a laserable medium. Preferably flanged, undoped end-caps are attached to both ends of the laserable medium. Due to the low scatter requirements for the interface between the end-caps and the laser rod, a non-adhesive method of bonding is utilized such as optical contacting combined with a subsequent heat treatment of the optically contacted composite. The non-bonded end surfaces of the flanged end-caps are coated with laser cavity coatings appropriate for the lasing wavelength of the laser rod. A cooling jacket, sealably coupled to the flanged end-caps, surrounds the entire length of the laserable medium. Radiation from a pump source is focused by a lens duct and passed through at least one flanged end-cap into the laser rod. 14 figs.
Improved Characteristics of Laser Source of Ions Using a Frequency Mode Laser
DOE Office of Scientific and Technical Information (OSTI.GOV)
Khaydarov, R. T.
2008-04-07
We used a mass-spectrometric method to investigate the characteristics of laser-produced plasma ions depending on the nature of the target and on the parameters of the laser radiation. Experiments are carried out on porous Y{sub 2}O{sub 3} targets with different densities {rho}, subjected to a laser radiation, where the laser works in a frequency mode (v = l-12 Hz). We found that the laser frequency has a significant effect on the parameters of plasma ions: with increasing the frequency of the laser the charge, energy and intensity of ions increase for a given parameters of the target. This effect ismore » more pronounced for small densities of the target. We related these two effects to a non-linear ionization process in the plasma due to the formation of dense plasma volume inside the sample absorbing the laser radiation and to the change of the focusing conditions in the case of the frequency mode laser.« less
Over 0.5 MW green laser from sub-nanosecond giant pulsed microchip laser
NASA Astrophysics Data System (ADS)
Zheng, Lihe; Taira, Takunori
2016-03-01
A sub-nanosecond green laser with laser head sized 35 × 35 × 35 mm3 was developed from a giant pulsed microchip laser for laser processing on organic superconducting transistor with a flexible substrate. A composite monolithic Y3Al5O12 (YAG) /Nd:YAG/Cr4+:YAG/YAG crystal was designed for generating giant pulsed 1064 nm laser. A fibercoupled 30 W laser diode centered at 808 nm was used with pump pulse duration of 245 μs. The 532 nm green laser was obtained from a LiB3O5 (LBO) crystal with output energy of 150 μJ and pulse duration of 268 ps. The sub-nanosecond green laser is interesting for 2-D ablation patterns.
Laser shock microforming of aluminum foil with fs laser
NASA Astrophysics Data System (ADS)
Ye, Yunxia; Feng, Yayun; Xuan, Ting; Hua, Xijun; Hua, Yinqun
2014-12-01
Laser shock microforming of Aluminum(Al) foil through fs laser has been researched in this paper. The influences of confining layer, clamping method and impact times on induced dent depths were investigated experimentally. Microstructure of fs laser shock forming Al foil was observed through Transmission electron microscopy (TEM). Under the condition of tightly clamping, the dent depths increase with impact times and finally tend to saturating. Another new confining layer, the main component of which is polypropylene, was applied and the confining effect of it is better because of its higher impedance. TEM results show that dislocation is one of the main deformation mechanisms of fs laser shock forming Al foil. Specially, most of dislocations exist in the form of short and discrete dislocation lines. Parallel straight dislocation slip line also were observed. We analyzed that these unique dislocation arrangements are due to fs laser-induced ultra high strain rate.
NASA Technical Reports Server (NTRS)
Bufton, Jack L.; Harding, David J.; Garvin, James B.
1999-01-01
The Shuttle Laser Altimeter (SLA) is a Hitchhiker experiment that has flown twice; first on STS-72 in January 1996 and then on STS-85 in August 1997. Both missions produced successful laser altimetry and surface lidar data products from approximately 80 hours per mission of SLA data operations. A total of four Shuttle missions are planned for the SLA series. This paper documents SLA mission results and explains SLA pathfinder accomplishments at the mid-point in this series of Hitchhiker missions. The overall objective of the SLA mission series is the transition of the Goddard Space Flight Center airborne laser altimeter and lidar technology to low Earth orbit as a pathfinder for NASA operational space-based laser remote sensing devices. Future laser altimeter sensors will utilize systems and approaches being tested with SLA, including the Multi-Beam Laser Altimeter (MBLA) and the Geoscience Laser Altimeter System (GLAS). MBLA is the land and vegetation laser sensor for the NASA Earth System Sciences Pathfinder Vegetation Canopy Lidar (VCL) Mission, and GLAS is the Earth Observing System facility instrument on the Ice, Cloud, and Land Elevation Satellite (ICESat). The Mars Orbiting Laser Altimeter, now well into a multi-year mapping mission at the red planet, is also directly benefiting from SLA data analysis methods, just as SLA benefited from MOLA spare parts and instrument technology experience [5] during SLA construction in the early 1990s.
ERIC Educational Resources Information Center
Hawkins, Harry
2004-01-01
This article describes how to construct a laser level. This laser level can be made using a typical 4' (or shorter) bubble level and a small laser point. The laser unit is detachable, so the bubble level can also be used in the conventional way. However, the laser level works better than a simple bubble level. Making this inexpensive device is an…
The study of laser beam riding guided system based on 980nm diode laser
NASA Astrophysics Data System (ADS)
Qu, Zhou; Xu, Haifeng; Sui, Xin; Yang, Kun
2015-10-01
With the development of science and technology, precision-strike weapons has been considered to be important for winning victory in military field. Laser guidance is a major method to execute precision-strike in modern warfare. At present, the problems of primary stage of Laser guidance has been solved with endeavors of countries. Several technical aspects of laser-beam riding guided system have been mature, such as atmosphere penetration of laser beam, clutter inhibition on ground, laser irradiator, encoding and decoding of laser beam. Further, laser beam quality, equal output power and atmospheric transmission properties are qualified for warfare situation. Riding guidance instrument is a crucial element of Laser-beam riding guided system, and is also a vital element of airborne, vehicle-mounted and individual weapon. The optical system mainly consist of sighting module and laser-beam guided module. Photoelectric detector is the most important sensing device of seeker, and also the key to acquire the coordinate information of target space. Currently, in consideration of the 1.06 u m of wavelength applied in all the semi-active laser guided weapons systems, lithium drifting silicon photodiode which is sensitive to 1.06 u m of wavelength is used in photoelectric detector. Compared to Solid and gas laser, diode laser has many merits such as small volume, simple construction, light weight, long life, low lost and easy modulation. This article introduced the composition and operating principle of Laser-beam riding guided system based on 980 nm diode laser, and made a analysis of key technology; for instance, laser irradiator, modulating disk of component, laser zooming system. Through the use of laser diode, Laser-beam riding guided system is likely to have smaller shape and very light.
Nguyen, D.C.; Faulkner, G.E.
1990-08-14
A blue-green laser (450--550 nm) uses a host crystal doped with Tm[sup 3+]. The Tm[sup 3+] is excited through upconversion by a red pumping laser and an IR pumping laser to a state which transitions to a relatively lower energy level through emissions in the blue-green band, e.g., 450.20 nm at 75 K. The exciting laser may be tunable dye lasers or may be solid-state semiconductor laser, e.g., GaAlAs and InGaAlP. 3 figs.
Nguyen, Dinh C.; Faulkner, George E.
1990-01-01
A blue-green laser (450-550 nm) uses a host crystal doped with Tm.sup.3+. The Tm.sup.+ is excited through upconversion by a red pumping laser and an IR pumping laser to a state which transitions to a relatively lower energy level through emissions in the blue-green band, e.g., 450.20 nm at 75 K. The exciting laser may be tunable dye lasers or may be solid-state semiconductor laser, e.g., GaAlAs and InGaAlP.
Changes in Anthocyanin Production during Domestication of Citrus1[OPEN
Garcia-Lor, Andrés; Licciardello, Concetta; Las Casas, Giuseppina; Ramadugu, Chandrika; Krueger, Robert; Fanciullino, Anne-Laure; Froelicher, Yann
2017-01-01
Mandarin (Citrus reticulata), citron (Citrus medica), and pummelo (Citrus maxima) are important species of the genus Citrus and parents of the interspecific hybrids that constitute the most familiar commercial varieties of Citrus: sweet orange, sour orange, clementine, lemon, lime, and grapefruit. Citron produces anthocyanins in its young leaves and flowers, as do species in genera closely related to Citrus, but mandarins do not, and pummelo varieties that produce anthocyanins have not been reported. We investigated the activity of the Ruby gene, which encodes a MYB transcription factor controlling anthocyanin biosynthesis, in different accessions of a range of Citrus species and in domesticated cultivars. A white mutant of lemon lacks functional alleles of Ruby, demonstrating that Ruby plays an essential role in anthocyanin production in Citrus. Almost all the natural variation in pigmentation by anthocyanins in Citrus species can be explained by differences in activity of the Ruby gene, caused by point mutations and deletions and insertions of transposable elements. Comparison of the allelic constitution of Ruby in different species and cultivars also helps to clarify many of the taxonomic relationships in different species of Citrus, confirms the derivation of commercial varieties during domestication, elucidates the relationships within the subgenus Papeda, and allows a new genetic classification of mandarins. PMID:28196843
Space-qualified laser system for the BepiColombo Laser Altimeter.
Kallenbach, Reinald; Murphy, Eamonn; Gramkow, Bodo; Rech, Markus; Weidlich, Kai; Leikert, Thomas; Henkelmann, Reiner; Trefzger, Boris; Metz, Bodo; Michaelis, Harald; Lingenauber, Kay; DelTogno, Simone; Behnke, Thomas; Thomas, Nicolas; Piazza, Daniele; Seiferlin, Karsten
2013-12-20
The space-qualified design of a miniaturized laser for pulsed operation at a wavelength of 1064 nm and at repetition rates up to 10 Hz is presented. This laser consists of a pair of diode-laser pumped, actively q-switched Nd:YAG rod oscillators hermetically sealed and encapsulated in an environment of dry synthetic air. The system delivers at least 300 million laser pulses with 50 mJ energy and 5 ns pulse width (FWHM). It will be launched in 2017 aboard European Space Agency's Mercury Planetary Orbiter as part of the BepiColombo Laser Altimeter, which, after a 6-years cruise, will start recording topographic data from orbital altitudes between 400 and 1500 km above Mercury's surface.
NASA Technical Reports Server (NTRS)
Taghavi-Larigani, Shervin (Inventor); Vanzyl, Jakob J. (Inventor); Yariv, Amnon (Inventor)
2006-01-01
Tunable semiconductor lasers are disclosed requiring minimized coupling regions. Multiple laser embodiments employ ring resonators or ring resonator pairs using only a single coupling region with the gain medium are detailed. Tuning can be performed by changing the phase of the coupling coefficient between the gain medium and a ring resonator of the laser. Another embodiment provides a tunable laser including two Mach-Zehnder interferometers in series and a reflector coupled to a gain medium.
Laser physics and a review of laser applications in dentistry for children.
Martens, L C
2011-04-01
The aim of this introduction to this special laser issue is to describe some basic laser physics and to delineate the potential of laser-assisted dentistry in children. A brief review of the available laser literature was performed within the scope of paediatric dentistry. Attention was paid to soft tissue surgery, caries prevention and diagnosis, cavity preparation, comfort of the patient, effect on bacteria, long term pulpal vitality, endodontics in primary teeth, dental traumatology and low level laser therapy. Although there is a lack of sufficient evidence taking into account the highest standards for evidence-based dentistry, it is clear that laser application in a number of different aetiologies for soft tissue surgery in children has proven to be successful. Lasers provide a refined diagnosis of caries combined with the appropriate preventive adhesive dentistry after cavity preparation. This will further lead to a new wave of micro-dentistry based on 'filling without drilling'. It has become clear from a review of the literature that specific laser applications in paediatric dentistry have gained increasing importance. It can be concluded that children should be considered as amongst the first patients for receiving laser-assisted dentistry.
Laser-assisted bremsstrahlung and electron-positron pair creation in relativistic laser fields
DOE Office of Scientific and Technical Information (OSTI.GOV)
Loetstedt, Erik
2009-07-25
An electron submitted to a relativistically strong laser field emits Compton harmonics at frequencies satisfying the nonlinear Compton formula. We investigate the scenario when in addition to the laser field, also a nuclear Coulomb field is present to accelerate the electron. In this case we may speak about laser-assisted bremsstrahlung, with radiation resulting from the combined effect of the Coulomb and laser field. The theoretical method employed is fully relativistic quantum electrodynamics, where in particular the laser-dressed Dirac-Volkov propagator requires proper treatment. Electron-positron pair creation is a physical process related to bremsstrahlung by a crossing symmetry of quantum electrodynamics. Wemore » consider pair creation in the combined fields of a laser, a nucleus and a high-frequency photon. We show that the total number of created pairs is not affected by the laser, provided the energy of the high-energy photon exceeds the pair creation threshold, but that the differential cross section is strongly enhanced in a particular direction, making a small angle with the laser beam. The physical picture is that the electron-positron pair is created by the high-energy photon, and subsequently accelerated by the laser field.« less
NASA Astrophysics Data System (ADS)
Kuusela, Tom A.
2017-09-01
A He-Ne laser is an example of a class A laser, which can be described by a single nonlinear differential equation of the complex electric field. This laser system has only one degree of freedom and is thus inherently stable. A He-Ne laser can be driven to the chaotic condition when a large fraction of the output beam is injected back to the laser. In practice, this can be done simply by adding an external mirror. In this situation, the laser system has infinite degrees of freedom and therefore it can have a chaotic attractor. We show the fundamental laser equations and perform elementary stability analysis. In experiments, the laser intensity variations are measured by a simple photodiode circuit. The laser output intensity time series is studied using nonlinear analysis tools which can be found freely on the internet. The results show that the laser system with feedback has an attractor of a reasonably high dimension and that the maximal Lyapunov exponent is positive, which is clear evidence of chaotic behaviour. The experimental setup and analysis steps are so simple that the studies can even be implemented in the undergraduate physics laboratory.
NASA Technical Reports Server (NTRS)
1990-01-01
The principal method of dealing with coronary artery blockage is bypass surgery. A non-surgical alternative available to some patients is balloon angioplasty. For several years, medical researchers have been exploring another alternative that would help a wider circle of patients than the balloon treatment and entail less risk than bypass surgery. A research group is on the verge of an exciting development: laser angioplasty with a 'cool' type of laser, called an excimer laser, that does not damage blood vessel walls and offers non-surgical cleansing of clogged arteries with extraordinary precision. The system is the Dymer 200+ Excimer Laser Angioplasty System, developed by Advanced Intraventional Systems. Used in human clinical tests since 1987, the system is the first fully integrated 'cool' laser capable of generating the requisite laser energy and delivering the energy to target arteries. Thirteen research hospitals in the U.S. have purchased Dymer 200+ systems and used them in clinical trials in 121 peripheral and 555 coronary artery cases. The success rate in opening blocked coronary arteries is 85 percent, with fewer complications than in balloon angioplasty. Food and Drug Administration approval for the system is hoped for in the latter part of 1990. * Advanced Intraventional Systems became Spectranetics in 1994 and discontinued the product.
Femtosecond laser inscribed cladding waveguide lasers in Nd:LiYF4 crystals
NASA Astrophysics Data System (ADS)
Li, Shi-Ling; Huang, Ze-Ping; Ye, Yong-Kai; Wang, Hai-Long
2018-06-01
Depressed circular cladding, buried waveguides were fabricated in Nd:LiYF4 crystals with an ultrafast Yb-doped fiber master-oscillator power amplifier laser. Waveguides were optimized by varying the laser writing conditions, such as pulse energy, focus depth, femtosecond laser polarization and scanning velocity. Under optical pump at 799 nm, cladding waveguides showed continuous-wave laser oscillation at 1047 nm. Single- and multi-transverse modes waveguide laser were realized by varying the waveguide diameter. The maximum output power in the 40 μm waveguide is ∼195 mW with a slope efficiency of 34.3%. The waveguide lasers with hexagonal and cubic cladding geometry were also realized.
[Navigated retinal laser therapy].
Kernt, M; Ulbig, M; Kampik, A; Neubauer, A S
2013-08-01
Navigated laser therapy introduces for the first time computerized assistance systems for retinal laser therapy. The Navilas system offers high precision and safety and provides additional benefits regarding standardization of planning, execution, documentation and quality assurance. The current focus of clinical application for navigated laser therapy besides laser treatment after retinal vein occlusion and panretinal laser photocoagulation in proliferative diabetic retinopathy (PDR) is diabetic macular edema. Recent data indicate that combined initial anti-vascular endothelial growth factor (anti-VEGF) and navigated macular laser therapy allows achievement and maintenance of treatment success with a minimum number of interventions. Despite very promising results the current assessment of navigated laser therapy is still limited by the evidence available worldwide.
Ishii, Katsunori; Saiki, Masayuki; Hazama, Hisanao; Awazu, Kunio
2010-01-01
Mid-infrared (MIR) laser with a specific wavelength can excite the corresponding biomolecular site to regulate chemical, thermal and mechanical interactions to biological molecules and tissues. In laser surgery and medicine, tunable MIR laser irradiation can realize the selective and less-invasive treatments and the special diagnosis by vibrational spectroscopic information. This paper showed a novel selective therapeutic technique for a laser angioplasty of atherosclerotic plaques and a laser dental surgery of a carious dentin using a MIR tunable nanosecond pulsed laser.
Advanced Laser Architecture for Two-Step Laser Tandem Mass Spectrometer
NASA Technical Reports Server (NTRS)
Fahey, Molly E.; Li, Steven X.; Yu, Anthony W.; Getty, Stephanie A.
2016-01-01
Future astrobiology missions will focus on planets with significant astrochemical or potential astrobiological features, such as small, primitive bodies and the icy moons of the outer planets that may host diverse organic compounds. These missions require advanced instrument techniques to fully and unambiguously characterize the composition of surface and dust materials. Laser desorptionionization mass spectrometry (LDMS) is an emerging instrument technology for in situ mass analysis of non-volatile sample composition. A recent Goddard LDMS advancement is the two-step laser tandem mass spectrometer (L2MS) instrument to address the need for future flight instrumentation to deconvolve complex organic signatures. The L2MS prototype uses a resonance enhanced multi-photon laser ionization mechanism to selectively detect aromatic species from a more complex sample. By neglecting the aliphatic and inorganic mineral signatures in the two-step mass spectrum, the L2MS approach can provide both mass assignments and clues to structural information for an in situ investigation of non-volatile sample composition. In this paper we will describe our development effort on a new laser architecture that is based on the previously flown Lunar Orbiter Laser Altimeter (LOLA) laser transmitter for the L2MS instrument. The laser provides two discrete midinfrared wavelengths (2.8 m and 3.4 m) using monolithic optical parametric oscillators and ultraviolet (UV) wavelength (266 nm) on a single laser bench with a straightforward development path toward flight readiness.
Optical radiation hazards of laser welding processes. Part 1: Neodymium-YAG laser.
Rockwell, R J; Moss, C E
1983-08-01
High power laser devices are being used for numerous metalworking processes such as welding, cutting and heat treating. Such laser devices are totally enclosed either by the manufacturer or the end-user. When this is done, the total laser system is usually certified by the manufacturer following the federal requirements of the Code of Federal Regulations (CFR) 1040.10 and 10.40.11 as a Class I laser system. Similarly, the end-user may also reclassify an enclosed high-power laser into the Class I category following the requirements of the American National Standards Institute (ANSI) Z-136.1 (1980) standard. There are, however, numerous industrial laser applications where Class IV systems are required to be used in an unenclosed manner. In such applications, there is concern for both ocular and skin hazards caused by direct and scattered laser radiation, as well as potential hazards caused by the optical radiation created by the laser beam's interaction with the metal (i.e. the plume radiation). Radiant energy measurements are reported for both the scattered laser radiation and the resultant plume radiations which were produced during typical unenclosed Class IV Neodymium-YAG laser welding processes. Evaluation of the plume radiation was done with both radiometric and spectroradiometric measurement equipment. The data obtained were compared to applicable safety standards.
Lasers in endodontics: an overview
NASA Astrophysics Data System (ADS)
Frentzen, Matthias; Braun, Andreas; Koort, Hans J.
2002-06-01
The interest in endodontic use of dental laser systems is increasing. Developing laser technology and a better understanding of laser effects widened the spectrum of possible endodontic indications. Various laser systems including excimer-, argon+-, diode-, Nd:YAG-, Er:YAG- and CO2-lasers are used in pulp diagnosis, treatment of hypersensitivity, pulp capping, sterilization of root canals, root canal shaping and obturation or apicoectomy. With the development of new delivery systems - thin and flexible fibers - for many different wavelengths laser applications in endodontics may increase. Since laser devices are still relatively costly, access to them is limited. Most of the clinical applications are laser assisted procedures such as the removing of pulp remnants and debris or disinfection of infected root canals. The essential question is whether a laser can provide improved treatment over conventional care. To perform laser therapy in endodontics today different laser types with adopted wavelengths and pulse widths are needed, each specific to a particular application. Looking into the future we will need endodontic laser equipment providing optimal laser parameters for different treatment modalities. Nevertheless, the quantity of research reports from the last decade promises a genuine future for lasers in endodontics.
NASA Technical Reports Server (NTRS)
Stein, Alexander
1988-01-01
A method of determining the emissivity of a hot target from a laser-based reflectance measurement which is conducted simultaneously with a measurement of the target radiance is described. Once the correct radiance and emissivity are determined, one calculates the true target temperature from these parameters via the Planck equations. The design and performance of a laser pyrometer is described. The accuracy of laser pyrometry and the effect of ambient radiance are addressed.
Bidirectional light-scattering image processing method for high-concentration jet sprays
NASA Astrophysics Data System (ADS)
Shimizu, I.; Emori, Y.; Yang, W.-J.; Shimoda, M.; Suzuki, T.
1985-01-01
In order to study the distributions of droplet size and volume density in high-concentration jet sprays, a new technique is developed, which combines the forward and backward light scattering method and an image processing method. A pulsed ruby laser is used as the light source. The Mie scattering theory is applied to the results obtained from image processing on the scattering photographs. The time history is obtained for the droplet size and volume density distributions, and the method is demonstrated by diesel fuel sprays under various injecting conditions. The validity of the technique is verified by a good agreement in the injected fuel volume distributions obtained by the present method and by injection rate measurements.
NASA Technical Reports Server (NTRS)
Kittleson, John K.; Yu, Yung H.
1987-01-01
Holographic interferometry and computerized aided tomography (CAT) are used to determine the transonic velocity field of a model rotor blade in hover. A pulsed ruby laser recorded 40 interferograms with a 2 ft dia view field near the model rotor blade tip operating at a tip Mach number of 0.90. After digitizing the interferograms and extracting the fringe order functions, the data are transferred to a CAT code. The CAT code then calculates the perturbation velocity in several planes above the blade surface. The values from the holography-CAT method compare favorably with previously obtained numerical computations in most locations near the blade tip. The results demonstrate the technique's potential for three dimensional transonic rotor flow studies.
1047 nm laser diode master oscillator Nd:YLF power amplifier laser system
NASA Technical Reports Server (NTRS)
Yu, A. W.; Krainak, M. A.; Unger, G. L.
1993-01-01
A master oscillator power amplifier (MOPA) laser transmitter system at 1047 nm wavelength using a semiconductor laser diode and a diode pumped solid state (Nd:YLF) laser (DPSSL) amplifier is described. A small signal gain of 23 dB, a near diffraction limited beam, 1 Gbit/s modulation rates and greater than 0.6 W average power are achieved. This MOPA laser has the advantage of amplifying the modulation signal from the laser diode master oscillator (MO) with no signal degradation.
CO laser angioplasty system: efficacy of manipulatable laser angioscope catheter
NASA Astrophysics Data System (ADS)
Arai, Tsunenori; Kikuchi, Makoto; Mizuno, Kyoichi; Sakurada, Masami; Miyamoto, Akira; Arakawa, Koh; Kurita, Akira; Nakamura, Haruo; Takeuchi, Kiyoshi; Utsumi, Atsushi; Akai, Yoshiro
1992-08-01
A percutaneous transluminal coronary angioplasty system using a unique combination of CO laser (5 micrometers ) and As-S infrared glass fiber under the guidance of a manipulatable laser angioscope catheter is described. The ablation and guidance functions of this system are evaluated. The angioplasty treatment procedure under angioscope guidance was studied by in vitro model experiment and in vivo animal experiment. The whole angioplasty system is newly developed. That is, a transportable compact medical CO laser device which can emit up to 10 W, a 5 F manipulatable laser angioscope catheter, a thin CO laser cable of which the diameter is 0.6 mm, an angioscope imaging system for laser ablation guidance, and a system controller were developed. Anesthetized adult mongrel dogs (n equals 5) with an artificial complete occlusion in the femoral artery and an artificial human vessel model including occluded or stenotic coronary artery were used. The manipulatability of the catheter was drastically improved (both rotation and bending), therefore, precise control of ablation to expand stenosis was obtained. A 90% artificial stenosis made of human yellow plaque in 4.0 mm diameter in the vessel was expanded to 70% stenosis by repetitive CO laser ablations of which total energy was 220 J. All procedures were performed and controlled under angioscope visualization.
Laser aircraft. [using kerosene
NASA Technical Reports Server (NTRS)
Hertzberg, A.; Sun, K.; Jones, W. S.
1979-01-01
The concept of a laser-powered aircraft is discussed. Laser flight would be completely compatible with existing airports and air-traffic control, with the airplane using kerosene only power, up to a cruising altitude of 9 km where the laser satellite would lock on and beam laser energy to it. Two major components make up the laser turbofan, a heat exchanger for converting laser radiation into thermal energy, and conventional turbomachinery. The laser power satellite would put out 42 Mw using a solar-powered thermal engine to generate electrical power for the closed-cycle supersonic electric discharge CO laser, whose radiators, heat exchangers, supersonic diffuser, and ducting will amount to 85% of the total subsystem mass. Relay satellites will be used to intercept the beam from the laser satellite, correct outgoing beam aberrations, and direct the beam to the next target. A 300-airplane fleet with transcontinental range is projected to save enough kerosene to equal the energy content of the entire system, including power and relay satellites, in one year.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-23
... non- Burmese covered articles, affirming that an established system of verified controls from the mine... Importation of Burmese and Non- Burmese Covered Articles of Jadeite, Rubies, and Articles of Jewelry... importation of Burmese and non-Burmese covered articles of jadeite, rubies, and articles of jewelry containing...
Longitudinal discharge laser baffles
Warner, Bruce E.; Ault, Earl R.
1994-01-01
The IR baffles placed between the window and the electrode of a longitudinal discharge laser improve laser performance by intercepting off-axis IR radiation from the laser and in doing so reduce window heating and subsequent optical distortion of the laser beam.
NASA Astrophysics Data System (ADS)
Zhou, Wenzhen; Gong, Yanjun; Wang, Mingjun; Gong, Lei
2016-10-01
technology. Laser one-dimensional range profile can reflect the characteristics of the target shape and surface material. These techniques were motivated by applications of laser radar to target discrimination in ballistic missile defense. The radar equation of pulse laser about cone is given in this paper. This paper demonstrates the analytical model of laser one-dimensional range profile of cone based on the radar equation of the pulse laser. Simulations results of laser one-dimensional range profiles of some cones are given. Laser one-dimensional range profiles of cone, whose surface material with diffuse lambertian reflectance, is given in this paper. Laser one-dimensional range profiles of cone, whose surface mater with diffuse materials whose retroreflectance can be modeled closely with an exponential term that decays with increasing incidence angles, is given in this paper. Laser one-dimensional range profiles of different pulse width of cone is given in this paper. The influences of surface material, pulse width, attitude on the one-dimensional range are analyzed. The laser two-dimensional range profile is two-dimensional scattering imaging of pulse laser of target. The two-dimensional range profile of roughness target can provide range resolved information. An analytical model of two-dimensional laser range profile of cone is proposed. The simulations of two-dimensional laser range profiles of some cones are given. Laser two-dimensional range profiles of cone, whose surface mater with diffuse lambertian reflectance, is given in this paper. Laser two-dimensional range profiles of cone, whose surface mater with diffuse materials whose retroreflectance can be modeled closely with an exponential term that decays with increasing incidence angles, is given in this paper. The influence of pulse width, surface material on laser two-dimensional range profile is analyzed. Laser one-dimensional range profile and laser two-dimensional range profile are called as laser
Color speckle in laser displays
NASA Astrophysics Data System (ADS)
Kuroda, Kazuo
2015-07-01
At the beginning of this century, lighting technology has been shifted from discharge lamps, fluorescent lamps and electric bulbs to solid-state lighting. Current solid-state lighting is based on the light emitting diodes (LED) technology, but the laser lighting technology is developing rapidly, such as, laser cinema projectors, laser TVs, laser head-up displays, laser head mounted displays, and laser headlamps for motor vehicles. One of the main issues of laser displays is the reduction of speckle noise1). For the monochromatic laser light, speckle is random interference pattern on the image plane (retina for human observer). For laser displays, RGB (red-green-blue) lasers form speckle patterns independently, which results in random distribution of chromaticity, called color speckle2).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Myers, J. D.
1985-06-25
A simplified, relatively inexpensive laser device, wherein the laser elements are fixed in a body exoskeleton of electrical insulating material having a low coefficient of thermal expansion. The preferred embodiment includes a shotgun type laser filter having parallel bores which receive the laser flashlamp and laser rod in fixed relation in a body chamber. The reflector surrounds the laser filter and retains the filter within the body chamber. In the preferred method of this invention, several controlled lasing pulses are generated with each illumination pulse of the flashlamp, substantially increasing the efficiency of the laser device. The number of pulsesmore » is generally controlled by increasing the voltage to the flashlamp. The rapid multiple lasing pulses generate an elongated plasma in a fluid medium, such as the vitreous fluid body of an eye which makes the laser device extemely efficient for treating glaucoma and other medical treatments.« less
Vibration Analysis Of Automotive Structures Using Holographic Interferometry
NASA Astrophysics Data System (ADS)
Brown, G. M.; Wales, R. R.
1983-10-01
Since 1979, Ford Motor Company has been developing holographic interferometry to supplement more conventional test methods to measure vehicle component vibrations. An Apollo PHK-1 Double Pulse Holographic Laser System was employed to visualize a variety of complex vibration modes, primarily on current production and prototype powertrain components. Design improvements to reduce powertrain response to problem excitations have been deter-mined through pulsed laser holography, and have, in several cases, been put into production in Ford vehicles. Whole-field definition of vibration related deflections provide continuity of information missed by accelerometer/modal analysis techniaues. Certain opera-tional problems, common among pulsed ruby holographic lasers, have reauired ongoing hardware and electronics improvements to minimize system downtime. Real-time, time-averaged and stroboscopic C. W. laser holographic techniques are being developed at Ford to complement the double pulse capabilities and provide rapid identification of modal frequencies and nodal lines for analysis of powertrain structures. Methods for mounting and exciting powertrains to minimize rigid body motions are discussed. Work at Ford will continue toward development of C. W. holographic techniques to provide refined test methodology dedicated to noise and vibration diagnostics with particular emphasis on semi-automated methods for quantifying displacement and relative phase using high resolution digitized video and computers. Continued use of refined pulsed and CW laser holographic interferometry for the analysis of complex structure vibrations seems assured.
NASA Technical Reports Server (NTRS)
1990-01-01
The Titan-CW Ti:sapphire (titanium-doped sapphire) tunable laser is an innovation in solid-state laser technology jointly developed by the Research and Solid State Laser Divisions of Schwartz Electro-optics, Inc. (SEO). SEO is producing the laser for the commercial market, an outgrowth of a program sponsored by Langley Research Center to develop Ti:sapphire technology for space use. SEO's Titan-CW series of Ti:sapphire tunable lasers have applicability in analytical equipment designed for qualitative analysis of carbohydrates and proteins, structural analysis of water, starch/sugar analyses, and measurements of salt in meat. Further applications are expected in semiconductor manufacture, in medicine for diagnosis and therapy, and in biochemistry.
Development of lasers optimized for pumping Ti:Al2O3 lasers
NASA Technical Reports Server (NTRS)
Rines, Glen A.; Schwarz, Richard A.
1994-01-01
Laboratory demonstrations that were completed included: (1) an all-solid-state, broadly tunable, single-frequency, Ti:Al2O3 master oscillator, and (2) a technique for obtaining 'long' (nominally 100- to 200-ns FWHM) laser pulses from a Q-switched, Nd oscillator at energy levels commensurate with straightforward amplification to the joule level. A diode-laser-pumped, Nd:YLF laser with intracavity SHG was designed, constructed, and evaluated. With this laser greater than 0.9 W of CW, output power at 523.5 nm with 10 W of diode-laser pump power delivered to the Nd:YLF crystal was obtained. With this laser as a pump source, for the first time, to our knowledge, an all solid-state, single frequency, Ti:Al203 laser with sufficient output power to injection seed a high-energy oscillator over a 20-nm bandwidth was demonstrated. The pulsed laser work succeeded in demonstrating pulse-stretching in a Q-switched Nd:YAG oscillator. Pulse energies greater than 50-mJ were obtained in pulses with 100- to 200-ns pulsewidths (FWHM).
Nd:YLF laser for airborne/spaceborne laser ranging
NASA Technical Reports Server (NTRS)
Dallas, Joseph L.; Selker, Mark D.
1993-01-01
In order to meet the need for light weight, long lifetime, efficient, short pulse lasers, a diode-pumped, Nd:YLF oscillator and regenerative amplifier is being developed. The anticipated output is 20 mJ per 10 picosecond pulse, running at a repetition rate of 40 Hz. The fundamental wavelength is at 1047 nm. The oscillator is pumped by a single laser diode bar and mode locked using an electro-optic, intra-cavity phase modulator. The output from the oscillator is injected as a seed into the regenerative amplifier. The regenerative amplifier laser crystal is optically pumped by two 60W quasi-cw laser diode bars. Each diode is collimated using a custom designed micro-lens bar. The injected 10 ps pulse from the oscillator is kept circulating within the regenerative amplifier until this nanojoule level seed pulse is amplified to 2-3 millijoules. At this point the pulse is ejected and sent on to a more standard single pass amplifier where the energy is boosted to 20 mJ. The footprint of the entire laser (oscillator-regenerative amplifier-amplifier) will fit on a 3 by 4 ft. optical pallet.
Molina, Wilson R; Marchini, Giovanni S; Pompeo, Alexandre; Sehrt, David; Kim, Fernando J; Monga, Manoj
2014-04-01
To evaluate the association of preoperative noncontrast computed tomography stone characteristics, laser settings, and stone composition with cumulative holmium:yttrium-aluminum-garnet (Ho:YAG) laser time/energy. We retrospectively reviewed patients who underwent semirigid/flexible ureteroscopy and Ho:YAG laser lithotripsy (200 or 365 μm laser fiber; 0.8-1.0 J energy; and 8-10 Hz rate) at 2 tertiary care centers (April 2010-May 2012). Studied parameters were as follows: patient's characteristics; stone characteristics (location, burden, hardness, and composition); total laser time and energy; and surgical outcomes. One hundred patients met our inclusion criteria. Mean stone size was 1.01 ± 0.42 cm and volume 0.33 ± 0.04 cm(3). Mean stone radiodensity was 990 ± 296 HU, and Hounsfield units density 13.8 ± 6.0 HU/mm. All patients were considered stone free. Stone size and volume had a significant positive correlation with laser energy (R = 0.516, P <.001; R = 0.621, P <.001) and laser time (R = 0.477, P <.001; R = 0.567, P <.001). When controlling for stone size, only the correlation between HU and laser time was significant (R = 0.262, P = .011). In the multivariate analysis, with exception of stone composition (P = .103), all parameters significantly increased laser energy (R(2) = 0.524). Multivariate analysis revealed a positive significant association of laser time with stone volume (P <.001) and Hounsfield units density (P <.001; R(2) = 0.512). In multivariate analysis for laser energy, only calcium phosphate stones required less energy to fragment compared with uric acid stones. No significant differences were found in the multivariate laser time model. Ho:YAG laser cumulative energy and total time are significantly affected by stone dimensions, hardness location, fiber size, and power. Kidney location, laser fiber size, and laser power have more influence on the final laser energy than on the total laser time. Calcium phosphate stones require less laser
A low-cost, tunable laser lock without laser frequency modulation
NASA Astrophysics Data System (ADS)
Shea, Margaret E.; Baker, Paul M.; Gauthier, Daniel J.
2015-05-01
Many experiments in optical physics require laser frequency stabilization. This can be achieved by locking to an atomic reference using saturated absorption spectroscopy. Often, the laser frequency is modulated and phase sensitive detection used. This method, while well-proven and robust, relies on expensive components, can introduce an undesirable frequency modulation into the laser, and is not easily frequency tuned. Here, we report a simple locking scheme similar to those implemented previously. We modulate the atomic resonances in a saturated absorption setup with an AC magnetic field created by a single solenoid. The same coil applies a DC field that allows tuning of the lock point. We use an auto-balanced detector to make our scheme more robust against laser power fluctuations and stray magnetic fields. The coil, its driver, and the detector are home-built with simple, cheap components. Our technique is low-cost, simple to setup, tunable, introduces no laser frequency modulation, and only requires one laser. We gratefully acknowledge the financial support of the NSF through Grant # PHY-1206040.
Injection-controlled laser resonator
Chang, J.J.
1995-07-18
A new injection-controlled laser resonator incorporates self-filtering and self-imaging characteristics with an efficient injection scheme. A low-divergence laser signal is injected into the resonator, which enables the injection signal to be converted to the desired resonator modes before the main laser pulse starts. This injection technique and resonator design enable the laser cavity to improve the quality of the injection signal through self-filtering before the main laser pulse starts. The self-imaging property of the present resonator reduces the cavity induced diffraction effects and, in turn, improves the laser beam quality. 5 figs.
Injection-controlled laser resonator
Chang, Jim J.
1995-07-18
A new injection-controlled laser resonator incorporates self-filtering and self-imaging characteristics with an efficient injection scheme. A low-divergence laser signal is injected into the resonator, which enables the injection signal to be converted to the desired resonator modes before the main laser pulse starts. This injection technique and resonator design enable the laser cavity to improve the quality of the injection signal through self-filtering before the main laser pulse starts. The self-imaging property of the present resonator reduces the cavity induced diffraction effects and, in turn, improves the laser beam quality.
Advances in laser and tissue interactions: laser microbeams and optical trapping (Invited Paper)
NASA Astrophysics Data System (ADS)
Serafetinides, Alexander A.; Makropoulou, Mersini; Papadopoulos, Dimitris; Papagiakoumou, Eirini; Pietreanu, D.
2005-04-01
The increasing use of lasers in biomedical research and clinical praxis leads to the development and application of new, non-invasive, therapeutic, surgical and diagnostic techniques. In laser surgery, the theory of ablation dictates that pulsed mid-infrared laser beams exhibit strong absorption by soft and hard tissues, restricting residual thermal damage to a minimum zone. Therefore, the development of high quality 3 μm lasers is considered to be an alternative for precise laser ablation of tissue. Among them are the high quality oscillator-two stages amplifier lasers developed, which will be described in this article. The beam quality delivered by these lasers to the biological tissue is of great importance in cutting and ablating operations. As the precision of the ablation is increased, the cutting laser interventions could well move to the microsurgery field. Recently, the combination of a laser scalpel with an optical trapping device, under microscopy control, is becoming increasingly important. Optical manipulation of microscopic particles by focused laser beams, is now widely used as a powerful tool for 'non-contact' micromanipulation of cells and organelles. Several laser sources are employed for trapping and varying laser powers are used in a broad range of applications of optical tweezers. For most of the lasers used, the focal spot of the trapping beam is of the order of a micron. As the trapped objects can vary in size from hundreds of nanometres to hundreds of microns, the technique has recently invaded in to the nanocosomos of genes and molecules. However, the use of optical trapping for quantitative research into biophysical processes requires accurate calculation of the optical forces and torques acting within the trap. The research and development efforts towards a mid-IR microbeam laser system, the design and realization efforts towards a visible laser trapping system and the first results obtained using a relatively new calibration method to
NASA Technical Reports Server (NTRS)
Lee, J. H.; Hohl, F.; Weaver, W. R. (Inventor)
1984-01-01
A solar pumped laser is described in which the lasant is a gas that will photodissociate and lase when subjected to sunrays. Sunrays are collected and directed onto the gas lasant to cause it to lase. Applications to laser propulsion and laser power transmission are discussed.
The Role of the CO2 Laser and Fractional CO2 Laser in Dermatology
Omi, Tokuya; Numano, Kayoko
2014-01-01
Background: Tremendous advances have been made in the medical application of the laser in the past few decades. Many diseases in the dermatological field are now indications for laser treatment that qualify for reimbursement by many national health insurance systems. Among laser types, the carbon dioxide (CO2) laser remains an important system for the dermatologist. Rationale: The lasers used in photosurgery have wavelengths that differ according to their intended use and are of various types, but the CO2 laser is one of the most widely used lasers in the dermatology field. With its wavelength in the mid-infrared at 10,600 nm, CO2 laser energy is wellabsorbed in water. As skin contains a very high water percentage, this makes the CO2 laser ideal for precise, safe ablation with good hemostasis. In addition to its efficacy in ablating benign raised lesions, the CO2 laser has been reported to be effective in the field of esthetic dermatology in the revision of acne scars as well as in photorejuvenation. With the addition of fractionation of the beam of energy into myriad microbeams, the fractional CO2 laser has offered a bridge between the frankly full ablative indications and the nonablative skin rejuvenation systems of the 2000s in the rejuvenation of photoaged skin on and off the face. Conclusions: The CO2 laser remains an efficient, precise and safe system for the dermatologist. Technological advances in CO2 laser construction have meant smaller spot sizes and greater precision for laser surgery, and more flexibility in tip sizes and protocols for fractional CO2 laser treatment. The range of dermatological applications of the CO2 laser is expected to continue to increase in the future. PMID:24771971
The Role of the CO2 Laser and Fractional CO2 Laser in Dermatology.
Omi, Tokuya; Numano, Kayoko
2014-03-27
Tremendous advances have been made in the medical application of the laser in the past few decades. Many diseases in the dermatological field are now indications for laser treatment that qualify for reimbursement by many national health insurance systems. Among laser types, the carbon dioxide (CO2) laser remains an important system for the dermatologist. The lasers used in photosurgery have wavelengths that differ according to their intended use and are of various types, but the CO2 laser is one of the most widely used lasers in the dermatology field. With its wavelength in the mid-infrared at 10,600 nm, CO2 laser energy is wellabsorbed in water. As skin contains a very high water percentage, this makes the CO2 laser ideal for precise, safe ablation with good hemostasis. In addition to its efficacy in ablating benign raised lesions, the CO2 laser has been reported to be effective in the field of esthetic dermatology in the revision of acne scars as well as in photorejuvenation. With the addition of fractionation of the beam of energy into myriad microbeams, the fractional CO2 laser has offered a bridge between the frankly full ablative indications and the nonablative skin rejuvenation systems of the 2000s in the rejuvenation of photoaged skin on and off the face. The CO2 laser remains an efficient, precise and safe system for the dermatologist. Technological advances in CO2 laser construction have meant smaller spot sizes and greater precision for laser surgery, and more flexibility in tip sizes and protocols for fractional CO2 laser treatment. The range of dermatological applications of the CO2 laser is expected to continue to increase in the future.
Qualification of Laser Diode Arrays for Mercury Laser Altimeter Mission
NASA Technical Reports Server (NTRS)
Stephen, Mark; Vasilyev, Aleksey; Schafer, John; Allan, Graham R.
2004-01-01
NASA's requirements for high reliability, high performance satellite laser instruments have driven the investigation of many critical components; specifically, 808 nm laser diode array (LDA) pump devices. The MESSENGER mission is flying the Mercury Laser Altimeter (MLA) which is a diode-pumped Nd:YAG laser instrument designed to map the topography of Mercury. The environment imposed on the instrument by the orbital dynamics places special requirements on the laser diode arrays. In order to limit the radiative heating of the satellite from the surface of Mercury, the satellite is designed to have a highly elliptical orbit. The satellite will heat near perigee and cool near apogee. The laser power is cycled during these orbits so that the laser is on for only 30 minutes (perigee) in a 12 hour orbit. The laser heats 10 C while powered up and cools while powered down. In order to simulate these operational conditions, we designed a test to measure the LDA performance while being temperature and power cycled. Though the mission requirements are specific to NASA and performance requirements are derived from unique operating conditions, the results are general and widely applicable. We present results on the performance of twelve LDAs operating for several hundred million pulses. The arrays are 100 watt, quasi-CW, conductively-cooled, 808 nm devices. Prior to testing, we fully characterize each device to establish a baseline for individual array performance and status. Details of this characterization can be found in reference. Arrays are divided into four groups and subjected to the temperature and power cycling matrix are shown.
Laser-induced reduction of graphene oxide powders by high pulsed ultraviolet laser irradiations
NASA Astrophysics Data System (ADS)
Yang, Chii-Rong; Tseng, Shih-Feng; Chen, Yu-Ting
2018-06-01
This study aims to develop a laser-induced reduction approach for graphene oxide (GO) powders fabricated by using high pulsed ultraviolet laser irradiations. Before and after the laser irradiation with different fluences, the physical and electrical properties of homemade GO powders and reduced graphene oxide (rGO) powders were measured and analyzed using Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), surface area analyzer, and four-point probe instrument. The laser irradiation parameters included the pulse repetition frequency of 100 kHz, the scanning speed of galvanometers of 50 mm/s, the number of laser irradiated cycles of 10, and the laser fluences of ranging from 0.153 mJ/cm2 to 0.525 mJ/cm2. The laser reduction experiments of GO powders demonstrated that the largest relative intensity of the 2D peak and specific surface area were found at the laser fluence of 0.438 mJ/cm2. Moreover, the electrical resistance sharply decreased from 280 MΩ in the initial GO powders to 0.267 MΩ in rGO powders at a laser irradiation fluence of 0.438. The C/O ratio was increased from 0.232 in the initial GO powders to 1.86 in the rGO powders at a laser irradiation fluence of 0.525 mJ/cm2; furthermore, the C/O ratios increased with increasing the laser fluences.
Distributed ultrafast fibre laser
Liu, Xueming; Cui, Yudong; Han, Dongdong; Yao, Xiankun; Sun, Zhipei
2015-01-01
A traditional ultrafast fibre laser has a constant cavity length that is independent of the pulse wavelength. The investigation of distributed ultrafast (DUF) lasers is conceptually and technically challenging and of great interest because the laser cavity length and fundamental cavity frequency are changeable based on the wavelength. Here, we propose and demonstrate a DUF fibre laser based on a linearly chirped fibre Bragg grating, where the total cavity length is linearly changeable as a function of the pulse wavelength. The spectral sidebands in DUF lasers are enhanced greatly, including the continuous-wave (CW) and pulse components. We observe that all sidebands of the pulse experience the same round-trip time although they have different round-trip distances and refractive indices. The pulse-shaping of the DUF laser is dominated by the dissipative processes in addition to the phase modulations, which makes our ultrafast laser simple and stable. This laser provides a simple, stable, low-cost, ultrafast-pulsed source with controllable and changeable cavity frequency. PMID:25765454
Dynamics of Superradiant Lasers
NASA Astrophysics Data System (ADS)
Thompson, James
2014-05-01
A superradiant laser has been shown to operate with less than one photon on average inside of the optical cavity. In this regime, almost all of the phase information of the laser is stored in the atoms rather than the cavity field. As a result, the laser's phase is highly insensitive to both technical and fundamental thermal cavity mirror vibrations. This vibration noise presently limits the coherence of the best lasers as well as the precision of the optical lattice clocks that these lasers interrogate. We have explored the physics of superradiant lasers utilizing Raman transitions between hyperfine states in rubidium to mimic narrow optical transitions. In this talk, we will discuss the amplitude stability of our superradiant Raman laser, and the dynamics of phase synchronization in our system. We will also consider the prospects for future superradiant lasers that would lase on the same highly-forbidden transitions used in optical lattice clocks. We acknowledge support from DARPA QUASAR, ARO, NIST, and the NSF PFC.
NASA Astrophysics Data System (ADS)
Faria Junior, Paulo E.; Xu, Gaofeng; Chen, Yang-Fang; Sipahi, Guilherme M.; Žutić, Igor
2017-03-01
Semiconductor lasers are strongly altered by adding spin-polarized carriers. Such spin lasers could overcome many limitations of their conventional (spin-unpolarized) counterparts. While the vast majority of experiments in spin lasers employed zinc-blende semiconductors, the room-temperature electrical manipulation was first demonstrated in wurtzite GaN-based lasers. However, the underlying theoretical description of wurtzite spin lasers is still missing. To address this situation, focusing on (In,Ga)N-based wurtzite quantum wells, we develop a theoretical framework in which the calculated microscopic spin-dependent gain is combined with a simple rate equation model. A small spin-orbit coupling in these wurtzites supports simultaneous spin polarizations of electrons and holes, providing unexplored opportunities to control spin lasers. For example, the gain asymmetry, as one of the key figures of merit related to spin amplification, can change the sign by simply increasing the carrier density. The lasing threshold reduction has a nonmonotonic dependence on electron-spin polarization, even for a nonvanishing hole spin polarization.
Diode lasers optimized in brightness for fiber laser pumping
NASA Astrophysics Data System (ADS)
Kelemen, M.; Gilly, J.; Friedmann, P.; Hilzensauer, S.; Ogrodowski, L.; Kissel, H.; Biesenbach, J.
2018-02-01
In diode laser applications for fiber laser pumping and fiber-coupled direct diode laser systems high brightness becomes essential in the last years. Fiber coupled modules benefit from continuous improvements of high-power diode lasers on chip level regarding output power, efficiency and beam characteristics resulting in record highbrightness values and increased pump power. To gain high brightness not only output power must be increased, but also near field widths and far field angles have to be below a certain value for higher power levels because brightness is proportional to output power divided by beam quality. While fast axis far fields typically show a current independent behaviour, for broadarea lasers far-fields in the slow axis suffer from a strong current and temperature dependence, limiting the brightness and therefore their use in fibre coupled modules. These limitations can be overcome by carefully optimizing chip temperature, thermal lensing and lateral mode structure by epitaxial and lateral resonator designs and processing. We present our latest results for InGaAs/AlGaAs broad-area single emitters with resonator lengths of 4mm emitting at 976nm and illustrate the improvements in beam quality over the last years. By optimizing the diode laser design a record value of the brightness for broad-area lasers with 4mm resonator length of 126 MW/cm2sr has been demonstrated with a maximum wall-plug efficiency of more than 70%. From these design also pump modules based on 9 mini-bars consisting of 5 emitters each have been realized with 360W pump power.
Investigation of laser-tissue interaction in medicine by means of laser spectroscopic measurements
NASA Astrophysics Data System (ADS)
Lademann, Juergen; Weigmann, Hans-Juergen
1995-01-01
Toxic and carcinogenic substances were produced during laser application in medicine for the cutting and evaporation of tissue. The laser smoke presents a danger potential for the medical staff and the patients. The laser tissue interaction process was investigated by means of laser spectroscopic measurements which give the possibility of measuring metastable molecular states directly as a prerequisite to understand and to influence fundamental laser tissue interaction processes in order to reduce the amount of harmful chemicals. Highly excited atomic and molecular states and free radicals (CN, OH, C2, CH, CH2) have been detected applying spontaneous and laser induced fluorescence methods. It was found that the formation of harmful substances in the laser plumes can be reduced significantly by optimization of the surrounding gas atmosphere. A high content of oxygen or water in the interaction zone has been found, in agreement with the results of classical and analytical methods, as a suitable way to decrease pollutant emission. The experimental methods and the principal results are applicable not only in laser medicine but in laser material treatment generally.
NASA Astrophysics Data System (ADS)
d'Orgeville, C.; Fetzer, G.
This presentation recalls the history of sodium guide star laser systems used in astronomy and space situational awareness adaptive optics, analysing the impact that sodium laser technology evolution has had on routine telescope operations. While it would not be practical to describe every single sodium guide star laser system developed to date, it is possible to characterize their evolution in broad technology terms. The first generation of sodium lasers used dye laser technology to create the first sodium laser guide stars in Hawaii, California, and Spain in the late 1980's and 1990's. These experimental systems were turned into the first laser guide star facilities to equip medium-to-large diameter adaptive optics telescopes, opening a new era of LGS AO-enabled diffraction-limited imaging from the ground. Although they produced exciting scientific results, these laser guide star facilities were large, power-hungry and messy. In the USA, a second-generation of sodium lasers was developed in the 2000's that used cleaner, yet still large and complex, solid-state laser technology. These are the systems in routine operation at the 8-10m class astronomical telescopes and 4m-class satellite imaging facilities today. Meanwhile in Europe, a third generation of sodium lasers was being developed using inherently compact and efficient fiber laser technology, and resulting in the only commercially available sodium guide star laser system to date. Fiber-based sodium lasers will be deployed at two astronomical telescopes and at least one space debris tracking station this year. Although highly promising, these systems remain significantly expensive and they have yet to demonstrate high performance in the field. We are proposing to develop a fourth generation of sodium lasers: based on semiconductor technology, these lasers could provide the final solution to the problem of sodium laser guide star adaptive optics for all astronomy and space situational awareness applications.
Soviet chemical laser research: pulsed lasers. Report for 1963--1970
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ksander, Y.
1971-11-01
The document reviews Soviet work on pulsed chemical lasers published in the open litarature in 1963-1970. Whereas U. S. research combines the approaches of physics, quantum electrodynamics, and aerodynamics, Soviet laser research is heavily (and expertly) oriented to understanding the chemical reactions. They prefer pulsed to cw systems, concentrating on kinetics of vibrationally excited diatomic systems. The documents describe gas lasers with discharge, photolytic, and other initiation and includes research on HN/sub 3/ + CO/sub 2/ mixtures, and means of controlling reaction rates by resonant coupling and selective heating. The report also proposes a laser based on photorecombination of atoms.
Laser fusion neutron source employing compression with short pulse lasers
Sefcik, Joseph A; Wilks, Scott C
2013-11-05
A method and system for achieving fusion is provided. The method includes providing laser source that generates a laser beam and a target that includes a capsule embedded in the target and filled with DT gas. The laser beam is directed at the target. The laser beam helps create an electron beam within the target. The electron beam heats the capsule, the DT gas, and the area surrounding the capsule. At a certain point equilibrium is reached. At the equilibrium point, the capsule implodes and generates enough pressure on the DT gas to ignite the DT gas and fuse the DT gas nuclei.