Sample records for s1c prototype reactor

  1. Quantity and management of spent fuel from prototype and research reactors in Germany

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dorr, Sabine; Bollingerfehr, Wilhelm; Filbert, Wolfgang

    Within the scope of an R and D project (project identification number FKZ 02 S 8679) sponsored by BMBF (Federal Ministry of Education and Research), the current state of storage and management of fuel elements from prototype and research reactors was established, and an approach for their future storage/management was developed. The spent fuels from prototype and research reactors in Germany that require disposal were specified and were described in regard to their repository-relevant characteristics. As there are currently no casks licensed for disposal in Germany, descriptions of casks that were considered to be suitable were provided. Based on themore » information provided on the spent fuel from prototype and research reactors and the potential casks, a technical disposal concept was developed. In this context, concepts to integrate the spent fuel from prototype and research reactors into existing disposal concepts for spent fuel from German nuclear power plants and for waste from reprocessing were developed for salt and clay formations. (authors)« less

  2. Prototype development and demonstration for response, emergency staging, communications, uniform management, and evacuation (R.E.S.C.U.M.E.) : R.E.S.C.U.M.E. prototype system architecture.

    DOT National Transportation Integrated Search

    2014-01-01

    This document provides the high-level system architecture for the Prototype Development and Demonstration of a R.E.S.C.U.M.E. system. The requirements addressed in this document are based upon those that can be found in previous R.E.S.C.U.M.E. report...

  3. Space station prototype Sabatier reactor design verification testing

    NASA Technical Reports Server (NTRS)

    Cusick, R. J.

    1974-01-01

    A six-man, flight prototype carbon dioxide reduction subsystem for the SSP ETC/LSS (Space Station Prototype Environmental/Thermal Control and Life Support System) was developed and fabricated for the NASA-Johnson Space Center between February 1971 and October 1973. Component design verification testing was conducted on the Sabatier reactor covering design and off-design conditions as part of this development program. The reactor was designed to convert a minimum of 98 per cent hydrogen to water and methane for both six-man and two-man reactant flow conditions. Important design features of the reactor and test conditions are described. Reactor test results are presented that show design goals were achieved and off-design performance was stable.

  4. DOE`s annealing prototype demonstration projects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Warren, J.; Nakos, J.; Rochau, G.

    1997-02-01

    One of the challenges U.S. utilities face in addressing technical issues associated with the aging of nuclear power plants is the long-term effect of plant operation on reactor pressure vessels (RPVs). As a nuclear plant operates, its RPV is exposed to neutrons. For certain plants, this neutron exposure can cause embrittlement of some of the RPV welds which can shorten the useful life of the RPV. This RPV embrittlement issue has the potential to affect the continued operation of a number of operating U.S. pressurized water reactor (PWR) plants. However, RPV material properties affected by long-term irradiation are recoverable throughmore » a thermal annealing treatment of the RPV. Although a dozen Russian-designed RPVs and several U.S. military vessels have been successfully annealed, U.S. utilities have stated that a successful annealing demonstration of a U.S. RPV is a prerequisite for annealing a licensed U.S. nuclear power plant. In May 1995, the Department of Energy`s Sandia National Laboratories awarded two cost-shared contracts to evaluate the feasibility of annealing U.S. licensed plants by conducting an anneal of an installed RPV using two different heating technologies. The contracts were awarded to the American Society of Mechanical Engineers (ASME) Center for Research and Technology Development (CRTD) and MPR Associates (MPR). The ASME team completed its annealing prototype demonstration in July 1996, using an indirect gas furnace at the uncompleted Public Service of Indiana`s Marble Hill nuclear power plant. The MPR team`s annealing prototype demonstration was scheduled to be completed in early 1997, using a direct heat electrical furnace at the uncompleted Consumers Power Company`s nuclear power plant at Midland, Michigan. This paper describes the Department`s annealing prototype demonstration goals and objectives; the tasks, deliverables, and results to date for each annealing prototype demonstration; and the remaining annealing technology

  5. The moving-ring field-reversed mirror prototype reactor

    NASA Astrophysics Data System (ADS)

    Smith, A. C., Jr.; Carlson, G. A.; Fleischmann, H. H.; Grossman, W., Jr.; Kammash, T.; Schultz, K. R.; Woodall, D. M.

    1981-03-01

    A prototype fusion reactor was designed based on magnetic field reversed plasma confinement. A set of physics, technology, and mechanical design criteria were developed in order to make this concept attractive. Six major criteria guide the commercial prototype design. The prototype must: (1) produce net electricity decisively P sub net 70% of P sub gross; (2) scale to an economical commercial plant and have small physical size; (3) have all features required of a correcial upgrade plant (H-3 breeding, etc.); (4) minimize exotic technology and maintenance complexity; (5) promise significantly lower safety hazards than fission plants (environmentally and socially acceptable); and (6) be modular in design to permit repetitive production of components.

  6. Prototype development and demonstration for response, emergency staging, communications, uniform management, and evacuation (R.E.S.C.U.M.E.) : R.E.S.C.U.M.E. prototype system design document.

    DOT National Transportation Integrated Search

    2014-04-01

    This report documents the System Design Document (SDD) for the prototype development and demonstration of the Response, Emergency Staging, Communications, Uniform Management, and Evacuation (R.E.S.C.U.M.E.) application bundle, with a focus on the Inc...

  7. Test of a prototype neutron spectrometer based on diamond detectors in a fast reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Osipenko, M.; Ripani, M.; Ricco, G.

    2015-07-01

    A prototype of neutron spectrometer based on diamond detectors has been developed. This prototype consists of a {sup 6}Li neutron converter sandwiched between two CVD diamond crystals. The radiation hardness of the diamond crystals makes it suitable for applications in low power research reactors, while a low sensitivity to gamma rays and low leakage current of the detector permit to reach good energy resolution. A fast coincidence between two crystals is used to reject background. The detector was read out using two different electronic chains connected to it by a few meters of cable. The first chain was based onmore » conventional charge-sensitive amplifiers, the other used a custom fast charge amplifier developed for this purpose. The prototype has been tested at various neutron sources and showed its practicability. In particular, the detector was calibrated in a TRIGA thermal reactor (LENA laboratory, University of Pavia) with neutron fluxes of 10{sup 8} n/cm{sup 2}s and at the 3 MeV D-D monochromatic neutron source named FNG (ENEA, Rome) with neutron fluxes of 10{sup 6} n/cm{sup 2}s. The neutron spectrum measurement was performed at the TAPIRO fast research reactor (ENEA, Casaccia) with fluxes of 10{sup 9} n/cm{sup 2}s. The obtained spectra were compared to Monte Carlo simulations, modeling detector response with MCNP and Geant4. (authors)« less

  8. C3I Rapid Prototype Investigation.

    DTIC Science & Technology

    1986-01-01

    feasibility of applying rapid K prototyping techniques to Air Force C3 1 system developments . This report presents the technical progress during the...computer tunctions. The cost to use each in terms of hardware, software, analysis, and needed further developments was assessed. Prototyping approaches were...acquirer, and developer are the ". basis for problems in C3I system developments . These problems destabilize r-. the requirements determination process

  9. Efficient infectious cell culture systems of the hepatitis C virus (HCV) prototype strains HCV-1 and H77.

    PubMed

    Li, Yi-Ping; Ramirez, Santseharay; Mikkelsen, Lotte; Bukh, Jens

    2015-01-01

    The first discovered and sequenced hepatitis C virus (HCV) genome and the first in vivo infectious HCV clones originated from the HCV prototype strains HCV-1 and H77, respectively, both widely used in research of this important human pathogen. In the present study, we developed efficient infectious cell culture systems for these genotype 1a strains by using the HCV-1/SF9_A and H77C in vivo infectious clones. We initially adapted a genome with the HCV-1 5'UTR-NS5A (where UTR stands for untranslated region) and the JFH1 NS5B-3'UTR (5-5A recombinant), including the genotype 2a-derived mutations F1464L/A1672S/D2979G (LSG), to grow efficiently in Huh7.5 cells, thus identifying the E2 mutation S399F. The combination of LSG/S399F and reported TNcc(1a)-adaptive mutations A1226G/Q1773H/N1927T/Y2981F/F2994S promoted adaptation of the full-length HCV-1 clone. An HCV-1 recombinant with 17 mutations (HCV1cc) replicated efficiently in Huh7.5 cells and produced supernatant infectivity titers of 10(4.0) focus-forming units (FFU)/ml. Eight of these mutations were identified from passaged HCV-1 viruses, and the A970T/I1312V/C2419R/A2919T mutations were essential for infectious particle production. Using CD81-deficient Huh7 cells, we further demonstrated the importance of A970T/I1312V/A2919T or A970T/C2419R/A2919T for virus assembly and that the I1312V/C2419R combination played a major role in virus release. Using a similar approach, we found that NS5B mutation F2994R, identified here from culture-adapted full-length TN viruses and a common NS3 helicase mutation (S1368P) derived from viable H77C and HCV-1 5-5A recombinants, initiated replication and culture adaptation of H77C containing LSG and TNcc(1a)-adaptive mutations. An H77C recombinant harboring 19 mutations (H77Ccc) replicated and spread efficiently after transfection and subsequent infection of naive Huh7.5 cells, reaching titers of 10(3.5) and 10(4.4) FFU/ml, respectively. Hepatitis C virus (HCV) was discovered in 1989 with

  10. The prototype fast reactor at Dounreay, Scotland. Process and engineering development for sodium removal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mann, A.; Herrick, R.; Gunn, J.

    2007-07-01

    Dounreay was home to commercial fast reactor development in the UK. Following the construction and operation of the Dounreay Fast Reactor, a sodium-cooled Prototype Fast Reactor (PFR), was constructed. PFR started operating in 1974, closed in 1994 and is presently being decommissioned. To date the bulk of the sodium has been removed and treated. Due to the design of the existing extraction system however, a sodium pool will remain in the heel of the reactor. To remove this sodium, a pump/camera system was developed, tested and deployed. The Water Vapour Nitrogen (WVN) process has been selected to allow removal ofmore » the final sodium residues from the reactor. Due to the design of the reactor and potential for structural damage should Normal WVN (which produces hydrated sodium hydroxide) be used, Low Concentration WVN (LC WVN) has been developed. Pilot scale testing has shown that it is possible treat the reactor within 18 months at a WVN concentration of up to 4% v/v and temperature of 120 deg. C. At present the equipment that will be used to apply LC WVN to the reactor is being developed at the detail design stage. and is expected to be deployed within the next few years. (authors)« less

  11. Prototype development and demonstration for response, emergency staging, communications, uniform management, and evacuation (R.E.S.C.U.M.E.) : R.E.S.C.U.M.E. final functional and performance requirements.

    DOT National Transportation Integrated Search

    2014-01-01

    This document provides the high-level functional and performance requirements for the Prototype Development and Demonstration of a R.E.S.C.U.M.E. system. The requirements included in this document are based upon those that can be found in previous R....

  12. METHODS OF CALCULATION FOR THE TREATMENT OF SHIELD HETEROGENEITIES IN THE PROTOTYPE FAST REACTOR.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Broughton, J.; Butler, J.; Brimstone, M.

    1969-10-31

    The radial shield of the sodium-cooled Prototype Fast Reactor is composed of graphite rods enclosed in steel tubes which are arranged in a lattice of seven rows round the periphery of the breeder. The outside diameter of these rods increases by about a factor of 2 between the inner temperature of about 600 deg C. The dimensions of the steel, graphite and sodium regions are large compared with the mean free paths of the predomination neutrons at intermediate energies; and homogenisation of the shield seriously underestimates the penetration, which is also enhanced by the presence of numerous irregularities associated withmore » nucleonic instrument thimbels, refuelling mechanisms and the primary coolant circuit. Methods of calculation have been developed for the solution of these problems, using both diffusion-theory and Monte Carlo techniques. The diffusion calculations have been accomplished with the COMPRASH and ATTOW codes; and a prototype Monet Carlo code named MOB has been developed, which takes a proper account of the radial shield geometry. The theoretical predictions are compared with measurements made in typical shield arrays on LIDO at Harwell and on the zero-energy fast reactor, ZEBRA, at Winfrith. The diffusion-theory and Monte Carlo approaches are also assessed as design tools taking into consideration accuracy, data preparation and computing time requirements. (auth)« less

  13. Performance of a full scale prototype detector at the BR2 reactor for the SoLid experiment

    NASA Astrophysics Data System (ADS)

    Abreu, Y.; Amhis, Y.; Arnold, L.; Ban, G.; Beaumont, W.; Bongrand, M.; Boursette, D.; Castle, B. C.; Clark, K.; Coupé, B.; Cussans, D.; De Roeck, A.; D'Hondt, J.; Durand, D.; Fallot, M.; Ghys, L.; Giot, L.; Guillon, B.; Ihantola, S.; Janssen, X.; Kalcheva, S.; Kalousis, L. N.; Koonen, E.; Labare, M.; Lehaut, G.; Manzanillas, L.; Mermans, J.; Michiels, I.; Moortgat, C.; Newbold, D.; Park, J.; Pestel, V.; Petridis, K.; Piñera, I.; Pommery, G.; Popescu, L.; Pronost, G.; Rademacker, J.; Ryckbosch, D.; Ryder, N.; Saunders, D.; Schune, M.-H.; Simard, L.; Vacheret, A.; Van Dyck, S.; Van Mulders, P.; van Remortel, N.; Vercaemer, S.; Verstraeten, M.; Weber, A.; Yermia, F.

    2018-05-01

    The SoLid collaboration has developed a new detector technology to detect electron anti-neutrinos at close proximity to the Belgian BR2 reactor at surface level. A 288 kg prototype detector was deployed in 2015 and collected data during the operational period of the reactor and during reactor shut-down. Dedicated calibration campaigns were also performed with gamma and neutron sources. This paper describes the construction of the prototype detector with a high control on its proton content and the stability of its operation over a period of several months after deployment at the BR2 reactor site. All detector cells provide sufficient light yields to achieve a target energy resolution of better than 20%/√E(MeV). The capability of the detector to track muons is exploited to equalize the light response of a large number of channels to a precision of 3% and to demonstrate the stability of the energy scale over time. Particle identification based on pulse-shape discrimination is demonstrated with calibration sources. Despite a lower neutron detection efficiency due to triggering constraints, the main backgrounds at the reactor site were determined and taken into account in the shielding strategy for the main experiment. The results obtained with this prototype proved essential in the design optimization of the final detector.

  14. Benchmark Evaluation of Dounreay Prototype Fast Reactor Minor Actinide Depletion Measurements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hess, J. D.; Gauld, I. C.; Gulliford, J.

    2017-01-01

    Historic measurements of actinide samples in the Dounreay Prototype Fast Reactor (PFR) are of interest for modern nuclear data and simulation validation. Samples of various higher-actinide isotopes were irradiated for 492 effective full-power days and radiochemically assayed at Oak Ridge National Laboratory (ORNL) and Japan Atomic Energy Research Institute (JAERI). Limited data were available regarding the PFR irradiation; a six-group neutron spectra was available with some power history data to support a burnup depletion analysis validation study. Under the guidance of the Organisation for Economic Co-Operation and Development Nuclear Energy Agency (OECD NEA), the International Reactor Physics Experiment Evaluation Projectmore » (IRPhEP) and Spent Fuel Isotopic Composition (SFCOMPO) Project are collaborating to recover all measurement data pertaining to these measurements, including collaboration with the United Kingdom to obtain pertinent reactor physics design and operational history data. These activities will produce internationally peer-reviewed benchmark data to support validation of minor actinide cross section data and modern neutronic simulation of fast reactors with accompanying fuel cycle activities such as transportation, recycling, storage, and criticality safety.« less

  15. CCSDS SM and C Mission Operations Interoperability Prototype

    NASA Technical Reports Server (NTRS)

    Lucord, Steven A.

    2010-01-01

    This slide presentation reviews the prototype of the Spacecraft Monitor and Control (SM&C) Operations for interoperability among other space agencies. This particular prototype uses the German Space Agency (DLR) to test the ideas for interagency coordination.

  16. Helium Leak Detection of Vessels in Fuel Transfer Cell (FTC) of Prototype Fast Breeder Reactor (PFBR)

    NASA Astrophysics Data System (ADS)

    Dutta, N. G.

    2012-11-01

    Bharatiya Nabhikiya Vidyut Nigam (BHAVINI) is engaged in construction of 500MW Prototype Fast Breeder Reactor (PFBR) at Kalpak am, Chennai. In this very important and prestigious national programme Special Product Division (SPD) of M/s Kay Bouvet Engg.pvt. ltd. (M/s KBEPL) Satara is contributing in a major way by supplying many important sub-assemblies like- Under Water trolley (UWT), Airlocks (PAL, EAL) Container and Storage Rack (CSR) Vessels in Fuel Transfer Cell (FTC) etc for PFBR. SPD of KBEPL caters to the requirements of Government departments like - Department of Atomic Energy (DAE), BARC, Defense, and Government undertakings like NPCIL, BHAVINI, BHEL etc. and other precision Heavy Engg. Industries. SPD is equipped with large size Horizontal Boring Machines, Vertical Boring Machines, Planno milling, Vertical Turret Lathe (VTL) & Radial drilling Machine, different types of welding machines etc. PFBR is 500 MWE sodium cooled pool type reactor in which energy is produced by fissions of mixed oxides of Uranium and Plutonium pellets by fast neutrons and it also breeds uranium by conversion of thorium, put along with fuel rod in the reactor. In the long run, the breeder reactor produces more fuel then it consumes. India has taken the lead to go ahead with Fast Breeder Reactor Programme to produce electricity primarily because India has large reserve of Thorium. To use Thorium as further fuel in future, thorium has to be converted in Uranium by PFBR Technology.

  17. 77 FR 30518 - Support of Deployment of Prototype Small Modular Reactors at the Savannah River Site

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... DEPARTMENT OF ENERGY Support of Deployment of Prototype Small Modular Reactors at the Savannah River Site AGENCY: Savannah River Operations Office, Department of Energy (DOE). ACTION: Notice of availability. SUMMARY: DOE-Savannah River Operations Office (SR), in conjunction with the Savannah River...

  18. 10 CFR 32.102 - Schedule C-prototype tests for calibration or reference sources containing americium-241 or...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Schedule C-prototype tests for calibration or reference... Licensed Items § 32.102 Schedule C—prototype tests for calibration or reference sources containing..., conduct prototype tests, in the order listed, on each of five prototypes of the source, which contains...

  19. IMMR Phase 1 Prototyping Plan Inputs

    NASA Technical Reports Server (NTRS)

    Vowell, C. W.; Johnson-Throop, Kathy; Smith, Bryon; Darcy, Jeannette

    2006-01-01

    This viewgraph presentation reviews the phase I plan of the prototype of the IMMR by the Multilateral Medical Operations Panel (MMOP) Medical Informatics & Technology (MIT) Working Group. It reviews the Purpose of IMMR Prototype Phase 1 (IPP1); the IPP1 Plan Overview, the IMMR Prototype Phase 1 Plan for PDDs and MIC and MIC-DDs, Plan for MICs, a nd the IPP1 objectives

  20. Irradiation creep of various ferritic alloys irradiated at {approximately}400{degrees}C in the PFR and FFTF reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Toloczko, M.B.; Garner, F.A.; Eiholzer, C.R.

    1997-04-01

    Three ferritic alloys were irradiated in two fast reactors to doses of 50 dpa or more at temperatures near 400{degrees}C. One martensitic alloy, HT9, was irradiated in both the FFTF and PFR reactors. PFR is the Prototype Fast Reactor in Dourneay, Scotland, and FFTF is the Fast Flux Test Facility in Richland, WA. D57 is a developmental alloy that was irradiated in PFR only, and MA957 is a Y{sub 2}O{sub 3} dispersion-hardened ferritic alloy that was irradiated only in FFTF. These alloys exhibited little or no void swelling at {approximately}400{degrees}C. Depending on the alloy starting condition, these steels develop amore » variety of non-creep strains early in the irradiation that are associated with phase changes. Each of these alloys creeps at a rate that is significantly lower than that of austenitic steels irradiated in the same experiments. The creep compliance for ferritic alloys in general appears to be {approximately}0.5 x 10{sup {minus}6} MPa{sup {minus}1} dpa{sup {minus}1}, independent of both composition and starting state. The addition of Y{sub 2}O{sub 3} as a dispersoid does not appear to change the creep behavior.« less

  1. Prototype Interoperability Document between NASA-JSC and DLR-GSOC Describing the CCSDS SM and C Mission Operations Prototype

    NASA Technical Reports Server (NTRS)

    Lucord, Steve A.; Gully, Sylvain

    2009-01-01

    The purpose of the PROTOTYPE INTEROPERABILITY DOCUMENT is to document the design and interfaces for the service providers and consumers of a Mission Operations prototype between JSC-OTF and DLR-GSOC. The primary goal is to test the interoperability sections of the CCSDS Spacecraft Monitor & Control (SM&C) Mission Operations (MO) specifications between both control centers. An additional goal is to provide feedback to the Spacecraft Monitor and Control (SM&C) working group through the Review Item Disposition (RID) process. This Prototype is considered a proof of concept and should increase the knowledge base of the CCSDS SM&C Mission Operations standards. No operational capabilities will be provided. The CCSDS Mission Operations (MO) initiative was previously called Spacecraft Monitor and Control (SM&C). The specifications have been renamed to better reflect the scope and overall objectives. The working group retains the name Spacecraft Monitor and Control working group and is under the Mission Operations and Information Services Area (MOIMS) of CCSDS. This document will refer to the specifications as SM&C Mission Operations, Mission Operations or just MO.

  2. Photon transitions in {psi}(2S) decays to {chi}{sub cJ}(1P) and {eta}{sub c}(1S)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Athar, S.B.; Avery, P.; Breva-Newell, L.

    2004-12-01

    We have studied the inclusive photon spectrum in {psi}(2S) decays using the CLEO III detector. We present the most precise measurements of electric dipole (E1) photon transition rates for {psi}(2S){yields}{gamma}{chi}{sub cJ}(1P) (J=0,1,2). We also confirm the hindered magnetic dipole (M1) transition, {psi}(2S){yields}{gamma}{eta}{sub c}(1S). However, the direct M1 transition {psi}(2S){yields}{gamma}{eta}{sub c}(2S) observed by the Crystal Ball as a narrow peak at a photon energy of 91 MeV is not found in our data.

  3. Human Factors and Technical Considerations for a Computerized Operator Support System Prototype

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ulrich, Thomas Anthony; Lew, Roger Thomas; Medema, Heather Dawne

    2015-09-01

    A prototype computerized operator support system (COSS) has been developed in order to demonstrate the concept and provide a test bed for further research. The prototype is based on four underlying elements consisting of a digital alarm system, computer-based procedures, PI&D system representations, and a recommender module for mitigation actions. At this point, the prototype simulates an interface to a sensor validation module and a fault diagnosis module. These two modules will be fully integrated in the next version of the prototype. The initial version of the prototype is now operational at the Idaho National Laboratory using the U.S. Departmentmore » of Energy’s Light Water Reactor Sustainability (LWRS) Human Systems Simulation Laboratory (HSSL). The HSSL is a full-scope, full-scale glass top simulator capable of simulating existing and future nuclear power plant main control rooms. The COSS is interfaced to the Generic Pressurized Water Reactor (gPWR) simulator with industry-typical control board layouts. The glass top panels display realistic images of the control boards that can be operated by touch gestures. A section of the simulated control board was dedicated to the COSS human-system interface (HSI), which resulted in a seamless integration of the COSS into the normal control room environment. A COSS demonstration scenario has been developed for the prototype involving the Chemical & Volume Control System (CVCS) of the PWR simulator. It involves a primary coolant leak outside of containment that would require tripping the reactor if not mitigated in a very short timeframe. The COSS prototype presents a series of operator screens that provide the needed information and soft controls to successfully mitigate the event.« less

  4. Rearrangements of mycoreovirus 1 S1, S2 and S3 induced by the multifunctional protein p29 encoded by the prototypic hypovirus Cryphonectria hypovirus 1 strain EP713.

    PubMed

    Tanaka, Toru; Sun, Liying; Tsutani, Kouhei; Suzuki, Nobuhiro

    2011-08-01

    Mycoreovirus 1 (MyRV1), a member of the family Reoviridae possessing a genome consisting of 11 dsRNA segments (S1-S11), infects the chestnut blight fungus and reduces its virulence (hypovirulence). Studies have previously demonstrated reproducible induction of intragenic rearrangements of MyRV1 S6 (S6L: almost full-length duplication) and S10 (S10ss: internal deletion of three-quarters of the ORF), mediated by the multifunctional protein p29 encoded by the prototype hypovirus, Cryphonectria hypovirus 1 (CHV1) strain EP713, of the family Hypoviridae with ssRNA genomes. The current study showed that CHV1 p29 also induced rearrangements of the three largest MyRV1 segments, S1, S2 and S3, which encode structural proteins. These rearranged segments involved in-frame extensions of almost two-thirds of the ORFs (S1L, S2L and S3L, respectively), which is rare for a reovirus rearrangement. MyRV1 variants carrying S1L, S2L or S3L always contained S10ss (MyRV1/S1L+S10ss2, MyRV1/S2L+S10ss2 or MyRV1/S3L+S10ss2). Levels of mRNAs for the rearranged and co-existing unaltered genome segments in fungal colonies infected with each of the MyRV1 variants appeared to be comparable to those for the corresponding normal segments in wild-type MyRV1-infected colonies, suggesting that the rearranged segments were fully competent for packaging and transcription. Protein products of the rearranged segments were detectable in fungal colonies infected with S2L MyRV1/S2L+S10ss2 and S3L MyRV1/S3L+S10ss2, whilst S1L-encoded protein remained undetectable. S1L, S2L and S3L were associated with enhancement of the aerial hyphae growth rate. This study has provided additional examples of MyRV1 intragenic rearrangements induced by p29, and suggests that normal S1, S2 and S3 are required for the symptoms caused by MyRV1.

  5. 153. ARAIII Reactor building (ARA608) Foundation plan. Aerojetgeneral 880area/GCRE608S1. Date: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    153. ARA-III Reactor building (ARA-608) Foundation plan. Aerojet-general 880-area/GCRE-608-S-1. Date: February 1958. Ineel index code no. 063-0608-60-013-102653. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  6. Evaluation of serological cross-reactivity and cross-neutralization between the United States porcine epidemic diarrhea virus prototype and S-INDEL-variant strains.

    PubMed

    Chen, Qi; Thomas, Joseph T; Giménez-Lirola, Luis G; Hardham, John M; Gao, Qinshan; Gerber, Priscilla F; Opriessnig, Tanja; Zheng, Ying; Li, Ganwu; Gauger, Phillip C; Madson, Darin M; Magstadt, Drew R; Zhang, Jianqiang

    2016-04-05

    At least two genetically different porcine epidemic diarrhea virus (PEDV) strains have been identified in the United States (U.S. PEDV prototype and S-INDEL-variant strains). The current serological assays offered at veterinary diagnostic laboratories for detection of PEDV-specific antibody are based on the U.S. PEDV prototype strain. The objectives of this study were: 1) isolate the U.S. PEDV S-INDEL-variant strain in cell culture; 2) generate antisera against the U.S. PEDV prototype and S-INDEL-variant strains by experimentally infecting weaned pigs; 3) determine if the various PEDV serological assays could detect antibodies against the U.S. PEDV S-INDEL-variant strain and vice versa. A U.S. PEDV S-INDEL-variant strain was isolated in cell culture in this study. Three groups of PEDV-negative, 3-week-old pigs (five pigs per group) were inoculated orally with a U.S. PEDV prototype isolate (previously isolated in our lab), an S-INDEL-variant isolate or virus-negative culture medium. Serum samples collected at 0, 7, 14, 21 and 28 days post inoculation were evaluated by the following PEDV serological assays: 1) indirect fluorescent antibody (IFA) assays using the prototype and S-INDEL-variant strains as indicator viruses; 2) virus neutralization (VN) tests against the prototype and S-INDEL-variant viruses; 3) PEDV prototype strain whole virus based ELISA; 4) PEDV prototype strain S1-based ELISA; and 5) PEDV S-INDEL-variant strain S1-based ELISA. The positive antisera against the prototype strain reacted to and neutralized both prototype and S-INDEL-variant viruses, and the positive antisera against the S-INDEL-variant strain also reacted to and neutralized both prototype and S-INDEL-variant viruses, as examined by IFA antibody assays and VN tests. Antibodies against the two PEDV strains could be detected by all three ELISAs although detection rates varied to some degree. These data indicate that the antibodies against U.S. PEDV prototype and S-INDEL-variant strains

  7. Top shield temperatures, C and K Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Agar, J.D.

    1964-12-28

    A modification program is now in progress at the C and K Reactors consisting of an extensive renovation of the graphite channels in the vertical safety rod ststems. The present VSR channels are being enlarged by a graphite coring operation and channel sleeves will be installed in the larger channels. One problem associated with the coring operation is the danger of damaging top thermal shield cooling tubes located close to the VSR channels to such an extent that these tubes will have to be removed from service. If such a condition should exist at one or a number of locationsmore » in the top shield of the reactors after reactor startup, the question remains -- what would the resulting temperatures be of the various components of the top shields? This study was initiated to determine temperature distributions in the top shield complex at the C and K Reactors for various top thermal shield coolant system conditions. Since the top thermal shield cooling system at C Reactor is different than those at the K Reactors, the study was conducted separately for the two different systems.« less

  8. Extruder system for high-throughput/steady-state hydrogen ice supply and application for pellet fueling of reactor-scale fusion experiments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Combs, S.K.; Foust, C.R.; Qualls, A.L.

    Pellet injection systems for the next-generation fusion devices, such as the proposed International Thermonuclear Experimental Reactor (ITER), will require feed systems capable of providing a continuous supply of hydrogen ice at high throughputs. A straightforward concept in which multiple extruder units operate in tandem has been under development at the Oak Ridge National Laboratory. A prototype with three large-volume extruder units has been fabricated and tested in the laboratory. In experiments, it was found that each extruder could provide volumetric ice flow rates of up to {approximately}1.3 cm{sup 3}/s (for {approximately}10 s), which is sufficient for fueling fusion reactors atmore » the gigawatt power level. With the three extruders of the prototype operating in sequence, a steady rate of {approximately}0.33 cm{sup 3}/s was maintained for a duration of 1 h. Even steady-state rates approaching the full ITER design value ({approximately}1 cm{sup 3}/s) may be feasible with the prototype. However, additional extruder units (1{endash}3) would facilitate operations at the higher throughputs and reduce the duty cycle of each unit. The prototype can easily accommodate steady-state pellet fueling of present large tokamaks or other near-term plasma experiments.« less

  9. Anaerobic treatment for C and S removal in "zero-discharge" paper mills: effects of process design on S removal efficiencies.

    PubMed

    van Lier, J B; Lens, P N; Pol, L W

    2001-01-01

    Stringent environmental laws in Europe and Northern America lead to the development towards closure of the process water streams in pulp and paper mills. Application of a "zero-discharge" process is already a feasible option for the board and packaging paper industry, provided in-line treatment is applied. Concomitant energy conservation inside the mill results in process water temperatures of 50-60 degrees C. Thermophilic anaerobic treatment complemented with appropriate post-treatment is considered as the most cost-effective solution to meet re-use criteria of the process water and to keep its temperature. In the proposed closed-cycle, the anaerobic treatment step removes the largest fraction of the biodegradable COD and eliminates "S" as H2S from the process stream, without the use of additional chemicals. The anaerobic step is regarded as the only possible location to bleed "S" from the process water cycle. In laboratory experiments, the effect of upward liquid velocity (Vupw) and the specific gas loading rate (Vgas) on the S removal capacity of thermophilic anaerobic bio-reactors was investigated. Acidifying, sulphate reducing sludge bed reactors were fed with partly acidified synthetic paper mill wastewater and were operated at 55 degrees C and pH 6. The reactors were operated at organic loading rates up to 50 g COD.l-1.day-1 at COD/SO4(2-) ratios of 10. The effect of Vupw was researched by comparing the performance of a UASB reactor operated at 1.0 m.h-1 and an EGSB reactor, operated at 6.8 m.h-1. The Vupw had a strong effect on the fermentation patterns. In the UASB reactor, acidification yielded H2, acetate and propionate, leading to an accumulation of reducing equivalents. These were partly disposed of by the production of n-butyrate and n-valerate from propionate. In the EGSB reactor net acetate consumption was observed as well as high volumetric gas (CO2 and CH4) production rates. The higher gas production rates in the EGSB reactor resulted in higher S

  10. Characterization of 14C in Swedish light water reactors.

    PubMed

    Magnusson, Asa; Aronsson, Per-Olof; Lundgren, Klas; Stenström, Kristina

    2008-08-01

    This paper presents the results of a 4-y investigation of 14C in different waste streams of both boiling water reactors (BWRs) and pressurized water reactors (PWRs). Due to the potential impact of 14C on human health, minimizing waste and releases from the nuclear power industry is of considerable interest. The experimental data and conclusions may be implemented to select appropriate waste management strategies and practices at reactor units and disposal facilities. Organic and inorganic 14C in spent ion exchange resins, process water systems, ejector off-gas and replaced steam generator tubes were analyzed using a recently developed extraction method. Separate analysis of the chemical species is of importance in order to model and predict the fate of 14C within process systems as well as in dose calculations for disposal facilities. By combining the results of this investigation with newly calculated production rates, mass balance assessments were made of the 14C originating from production in the coolant. Of the 14C formed in the coolant of BWRs, 0.6-0.8% was found to be accumulated in the ion exchange resins (core-specific production rate in the coolant of a 2,500 MWth BWR calculated to be 580 GBq GW(e)(-1) y(-1)). The corresponding value for PWRs was 6-10% (production rate in a 2,775 MWth PWR calculated to be 350 GBq GW(e)(-1) y(-1)). The 14C released with liquid discharges was found to be insignificant, constituting less than 0.5% of the production in the coolant. The stack releases, routinely measured at the power plants, were found to correspond to 60-155% of the calculated coolant production, with large variations between the BWR units.

  11. Light Water Reactor Sustainability Program, U.S. Efforts in Support of Examinations at Fukushima Daiichi-2017 Evaluations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Farmer, Mitchell T.

    Although the accident signatures from each unit at the Fukushima Daiichi Nuclear Power Station (NPS) [Daiichi] differ, much is not known about the end-state of core materials within these units. Some of this uncertainty can be attributed to a lack of information related to cooling system operation and cooling water injection. There is also uncertainty in our understanding of phenomena affecting: a) in-vessel core damage progression during severe accidents in boiling water reactors (BWRs), and b) accident progression after vessel failure (ex-vessel progression) for BWRs and Pressurized Water Reactors (PWRs). These uncertainties arise due to limited full scale prototypic data.more » Similar to what occurred after the accident at Three Mile Island Unit 2, these Daiichi units offer the international community a means to reduce such uncertainties by obtaining prototypic data from multiple full-scale BWR severe accidents. Information obtained from Daiichi is required to inform Decontamination and Decommissioning activities, improving the ability of the Tokyo Electric Power Company Holdings, Incorporated (TEPCO Holdings) to characterize potential hazards and to ensure the safety of workers involved with cleanup activities. This document, which has been updated to include FY2017 information, summarizes results from U.S. efforts to use information obtained by TEPCO Holdings to enhance the safety of existing and future nuclear power plant designs. This effort, which was initiated in 2014 by the Reactor Safety Technologies Pathway of the Department of Energy Office of Nuclear Energy Light Water Reactor (LWR) Sustainability Program, consists of a group of U.S. experts in LWR safety and plant operations that have identified examination needs and are evaluating TEPCO Holdings information from Daiichi that address these needs. Each year, annual reports include examples demonstrating that significant safety insights are being obtained in the areas of component performance

  12. Chemical compatibility issues associated with use of SiC/SiC in advanced reactor concepts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilson, Dane F.

    2015-09-01

    Silicon carbide/silicon carbide (SiC/SiC) composites are of interest for components that will experience high radiation fields in the High Temperature Gas Cooled Reactor (HTGR), the Very High Temperature Reactor (VHTR), the Sodium Fast Reactor (SFR), or the Fluoride-cooled High-temperature Reactor (FHR). In all of the reactor systems considered, reactions of SiC/SiC composites with the constituents of the coolant determine suitability of materials of construction. The material of interest is nuclear grade SiC/SiC composites, which consist of a SiC matrix [high-purity, chemical vapor deposition (CVD) SiC or liquid phase-sintered SiC that is crystalline beta-phase SiC containing small amounts of alumina-yttria impurity],more » a pyrolytic carbon interphase, and somewhat impure yet crystalline beta-phase SiC fibers. The interphase and fiber components may or may not be exposed, at least initially, to the reactor coolant. The chemical compatibility of SiC/SiC composites in the three reactor environments is highly dependent on thermodynamic stability with the pure coolant, and on reactions with impurities present in the environment including any ingress of oxygen and moisture. In general, there is a dearth of information on the performance of SiC in these environments. While there is little to no excess Si present in the new SiC/SiC composites, the reaction of Si with O 2 cannot be ignored, especially for the FHR, in which environment the product, SiO 2, can be readily removed by the fluoride salt. In all systems, reaction of the carbon interphase layer with oxygen is possible especially under abnormal conditions such as loss of coolant (resulting in increased temperature), and air and/ or steam ingress. A global outline of an approach to resolving SiC/SiC chemical compatibility concerns with the environments of the three reactors is presented along with ideas to quickly determine the baseline compatibility performance of SiC/SiC.« less

  13. TRIGA Mark II nuclear reactor facility. Final report, 1 July 1980--30 June 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ryan, B.C.

    1997-05-01

    This report is a final culmination of activities funded through the Department of Energy`s (DOE) University Reactor Sharing Program, Grant DE-FG02-80ER10273, during the period 1 July 1980 through 30 June 1995. Progress reports have been periodically issued to the DOE, namely the Reactor Facility Annual Reports C00-2082/2219-7 through C00-2082/10723-21, which are contained as an appendix to this report. Due to the extent of time covered by this grant, summary tables are presented. Table 1 lists the fiscal year financial obligations of the grant. As listed in the original grant proposals, the DOE grant financed 70% of project costs, namely themore » total amount spent of these projects minus materials costs and technical support. Thus the bulk of funds was spent directly on reactor operations. With the exception of a few years, spending was in excess of the grant amount. As shown in Tables 2 and 3, the Reactor Sharing grant funded a immense number of research projects in nuclear engineering, geology, animal science, chemistry, anthropology, veterinary medicine, and many other fields. A list of these users is provided. Out of the average 3000 visitors per year, some groups participated in classes involving the reactor such as Boy Scout Merit Badge classes, teacher`s workshops, and summer internships. A large number of these projects met the requirements for the Reactor Sharing grant, but were funded by the University instead.« less

  14. HMB-45, S-100, NK1/C3, and MART-1 in metastatic melanoma.

    PubMed

    Zubovits, Judit; Buzney, Elizabeth; Yu, Lawrence; Duncan, Lyn M

    2004-02-01

    The diagnosis of melanoma metastatic to lymph node remains a difficult problem given its histological diversity. We examined the staining patterns of S-100, NK1/C3, HMB-45, and MART-1 (DC10) in melanoma metastases to lymph nodes. Immunohistochemical stains were performed on tissue sections of 126 formalin-fixed lymph nodes from 126 patients with an established diagnosis of metastatic melanoma. A total of 98% of cases (123 of 126) stained positive for S-100, 93% (117 of 125) stained positive for NK1/C3, 82% (103 of 126) stained positive for MART-1, and 76% (95 of 125) stained positive for HMB-45. The distribution and intensity of staining varied among these markers. A diffuse staining pattern, defined as >50% of tumor cells stained, was observed in 83% of MART-1-positive cases but in only 56% of S-100-positive cases, 48% of NK1/C3-positive cases, and 34% of HMB-45-positive cases. A maximally intense signal was almost always observed for MART-1 (83% of positive cases) but was rarely observed for NK1/C3 (20%). S-100 and HMB-45 showed maximally intense staining in 50% and 54% of cases, respectively. S-100 and NK1/C3 stained both histiocytes and melanocytes, whereas MART-1 and HMB-45 stained only melanocytes. Seventy-eight cases (63%) stained positive for all 4 markers, 17 cases (14%) stained for all markers except HMB-45, 13 cases (10%) stained for all markers except MART-1, 6 cases (5%) stained only with S-100 and NK1/C3, 4 cases (3%) stained only with S-100 and HMB-45, and 2 cases stained for all markers except S-100. One case each stained for the following: only S-100, only S-100 and HMB-45, and all markers except NK1/C3. One case exhibited absence of staining for any of these markers. We demonstrate that lymph node metastases of melanoma are heterogeneous with regard to tumor marker expression. S-100 and NK1/C3 were the most sensitive stains for detecting metastatic melanoma; however, they both also stain other nontumor cells in lymph nodes. MART-1 did not stain

  15. Prototype Learning and Dissociable Categorization Systems in Alzheimer’s Disease

    PubMed Central

    Heindel, William C.; Festa, Elena K.; Ott, Brian R.; Landy, Kelly M.; Salmon, David P.

    2015-01-01

    Recent neuroimaging studies suggest that prototype learning may be mediated by at least two dissociable memory systems depending on the mode of acquisition, with A/Not-A prototype learning dependent upon a perceptual representation system located within posterior visual cortex and A/B prototype learning dependent upon a declarative memory system associated with medial temporal and frontal regions. The degree to which patients with Alzheimer’s disease (AD) can acquire new categorical information may therefore critically depend upon the mode of acquisition. The present study examined A/Not-A and A/B prototype learning in AD patients using procedures that allowed direct comparison of learning across tasks. Despite impaired explicit recall of category features in all tasks, patients showed differential patterns of category acquisition across tasks. First, AD patients demonstrated impaired prototype induction along with intact exemplar classification under incidental A/Not-A conditions, suggesting that the loss of functional connectivity within visual cortical areas disrupted the integration processes supporting prototype induction within the perceptual representation system. Second, AD patients demonstrated intact prototype induction but impaired exemplar classification during A/B learning under observational conditions, suggesting that this form of prototype learning is dependent on a declarative memory system that is disrupted in AD. Third, the surprisingly intact classification of both prototypes and exemplars during A/B learning under trial-and-error feedback conditions suggests that AD patients shifted control from their deficient declarative memory system to a feedback-dependent procedural memory system when training conditions allowed. Taken together, these findings serve to not only increase our understanding of category learning in AD, but to also provide new insights into the ways in which different memory systems interact to support the acquisition of

  16. UAS C2 Radio System - Final Phase 1 Development and Testing

    NASA Technical Reports Server (NTRS)

    Kerczewski, Robert; Shalkhauser, Kurt

    2017-01-01

    Phase 1 of the Command and Control Communications (C2) Subproject of NASA's UAS Integration in the National Airspace System Project included the development and testing of prototype C2 radio systems. This information paper provides an overview of the functionality and testing of the fifth and final Phase 1 generation of the prototype radio system.

  17. OpenStreetMap Collaborative Prototype, Phase 1

    USGS Publications Warehouse

    Wolf, Eric B.; Matthews, Greg D.; McNinch, Kevin; Poore, Barbara S.

    2011-01-01

    Phase One of the OpenStreetMap Collaborative Prototype (OSMCP) attempts to determine if the open source software developed for the OpenStreetMap (OSM, http://www.openstreetmap.org) can be used for data contributions and improvements that meet or exceed the requirements for integration into The National Map (http://www.nationalmap.gov). OpenStreetMap Collaborative Prototype Phase One focused on road data aggregated at the state level by the Kansas Data Access and Support Center (DASC). Road data from the DASC were loaded into a system hosted by the U.S. Geological Survey (USGS) National Geospatial Technical Operations Center (NGTOC) in Rolla, Missouri. U.S. Geological Survey editing specifications were developed by NGTOC personnel (J. Walters and G. Matthews, USGS, unpub. report, 2010). Interstate and U.S. Highways in the dataset were edited to the specifications by NGTOC personnel while State roads were edited by DASC personnel. Resulting data were successfully improved to meet standards for The National Map once the system and specifications were in place. The OSM software proved effective in providing a usable platform for collaborative data editing

  18. An Ultrasonic Scanning Technique for In-Situ `Bowing' Measurement of Prototype Fast Breeder Reactor Fuel Sub-Assembly

    NASA Astrophysics Data System (ADS)

    Swaminathan, K.; Asokane, C.; Sylvia, J. I.; Kalyanasundaram, P.; Swaminathan, P.

    2012-02-01

    An ultrasonic under-sodium scanner has been developed for deployment in Prototype Fast Breeder Reactor (PFBR) which is in advanced stage of construction at Kalpakkam, India. Its purpose is to scan the above-core plenum for detection, if any, of displacement of sub-assemblies. During its burn-up in the reactor, the head of a Fuel Sub-Assembly (FSA) may undergo a lateral shift from its original position (called `bowing') due to the fast neutron induced damage on its structural material. A simple scanning technique has been developed for measuring the extent of bowing in-situ. This paper describes a PC-controlled mock-up of the scanner used to implement the scanning technique and the results obtained of scanning a mock-up FSA head under water. The details of the liquid-sodium proof transducer developed for use in the PFBR scanner and its performance are also discussed.

  19. Design Skills and Prototyping for Defense Systems

    DTIC Science & Technology

    2015-04-30

    however, the utility of prototyping has had a demonstrably mixed record in defense acquisition. Some programs, such as the Manhattan Project , were...almost completely undefined. The first production reactors for the Manhattan Project suffered a near- catastrophic engineering design flaw stemming...architecture, as was seen in the F-117 and Manhattan Project development efforts. Architectural Prototyping Simply maintaining design teams or developing

  20. Cleanup Verification Package for the 118-C-1, 105-C Solid Waste Burial Ground

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    M. J. Appel and J. M. Capron

    2007-07-25

    This cleanup verification package documents completion of remedial action for the 118-C-1, 105-C Solid Waste Burial Ground. This waste site was the primary burial ground for general wastes from the operation of the 105-C Reactor and received process tubes, aluminum fuel spacers, control rods, reactor hardware, spent nuclear fuel and soft wastes.

  1. IBD Selection for the 288kg Prototype SoLid Module

    NASA Astrophysics Data System (ADS)

    Saunders, D.; SoLid Collaboration

    2017-09-01

    The SoLid experiment aims to make a measurement of very short baseline neutrino oscillations using reactor antineutrinos. Key to its sensitivity are the experiment’s high spatial and energy resolution, combined with a very suitable reactor source and excellent background rejection. Placed on the surface at just 5 m from the reactor core, the cosmic flux and reactor output lead to a challenging environment. The fine segmentation of the detector, 5 cm cubes, allows the topology of events to be studied to previously unseen precision. This offers new and unexplored handles for tackling these backgrounds - a key requirement for SoLid physics aims. Using the most recent SoLid prototype (288 kg, 20% scale), we present the first selection to focus on IBD signals. This includes descriptions of SoLid signals and backgrounds, and demonstration that the segmentation can lead to gains in orders of magnitude in background rejection.

  2. Combined Ceria Reduction and Methane Reforming in a Solar-Driven Particle-Transport Reactor.

    PubMed

    Welte, Michael; Warren, Kent; Scheffe, Jonathan R; Steinfeld, Aldo

    2017-09-20

    We report on the experimental performance of a solar aerosol reactor for carrying out the combined thermochemical reduction of CeO 2 and reforming of CH 4 using concentrated radiation as the source of process heat. The 2 kW th solar reactor prototype utilizes a cavity receiver enclosing a vertical Al 2 O 3 tube which contains a downward gravity-driven particle flow of ceria particles, either co-current or counter-current to a CH 4 flow. Experimentation under a peak radiative flux of 2264 suns yielded methane conversions up to 89% at 1300 °C for residence times under 1 s. The maximum extent of ceria reduction, given by the nonstoichiometry δ (CeO 2-δ ), was 0.25. The solar-to-fuel energy conversion efficiency reached 12%. The syngas produced had a H 2 :CO molar ratio of 2, and its calorific value was solar-upgraded by 24% over that of the CH 4 reformed.

  3. Combined Ceria Reduction and Methane Reforming in a Solar-Driven Particle-Transport Reactor

    PubMed Central

    2017-01-01

    We report on the experimental performance of a solar aerosol reactor for carrying out the combined thermochemical reduction of CeO2 and reforming of CH4 using concentrated radiation as the source of process heat. The 2 kWth solar reactor prototype utilizes a cavity receiver enclosing a vertical Al2O3 tube which contains a downward gravity-driven particle flow of ceria particles, either co-current or counter-current to a CH4 flow. Experimentation under a peak radiative flux of 2264 suns yielded methane conversions up to 89% at 1300 °C for residence times under 1 s. The maximum extent of ceria reduction, given by the nonstoichiometry δ (CeO2−δ), was 0.25. The solar-to-fuel energy conversion efficiency reached 12%. The syngas produced had a H2:CO molar ratio of 2, and its calorific value was solar-upgraded by 24% over that of the CH4 reformed. PMID:28966440

  4. Sodium Based Heat Pipe Modules for Space Reactor Concepts: Stainless Steel SAFE-100 Core

    NASA Technical Reports Server (NTRS)

    Martin, James J.; Reid, Robert S.

    2004-01-01

    A heat pipe cooled reactor is one of several candidate reactor cores being considered for advanced space power and propulsion systems to support future space exploration applications. Long life heat pipe modules, with designs verified through a combination of theoretical analysis and experimental lifetime evaluations, would be necessary to establish the viability of any of these candidates, including the heat pipe reactor option. A hardware-based program was initiated to establish the infrastructure necessary to build heat pipe modules. This effort, initiated by Los Alamos National Laboratory and referred to as the Safe Affordable Fission Engine (SAFE) project, set out to fabricate and perform non-nuclear testing on a modular heat pipe reactor prototype that can provide 100 kilowatt from the core to an energy conversion system at 700 C. Prototypic heat pipe hardware was designed, fabricated, filled, closed-out and acceptance tested.

  5. Reactor Dosimetry State of the Art 2008

    NASA Astrophysics Data System (ADS)

    Voorbraak, Wim; Debarberis, Luigi; D'Hondt, Pierre; Wagemans, Jan

    2009-08-01

    Oral session 1: Retrospective dosimetry. Retrospective dosimetry of VVER 440 reactor pressure vessel at the 3rd unit of Dukovany NPP / M. Marek ... [et al.]. Retrospective dosimetry study at the RPV of NPP Greifswald unit 1 / J. Konheiser ... [et al.]. Test of prototype detector for retrospective neutron dosimetry of reactor internals and vessel / K. Hayashi ... [et al.]. Neutron doses to the concrete vessel and tendons of a magnox reactor using retrospective dosimetry / D. A. Allen ... [et al.]. A retrospective dosimetry feasibility study for Atucha I / J. Wagemans ... [et al.]. Retrospective reactor dosimetry with zirconium alloy samples in a PWR / L. R. Greenwood and J. P. Foster -- Oral session 2: Experimental techniques. Characterizing the Time-dependent components of reactor n/y environments / P. J. Griffin, S. M. Luker and A. J. Suo-Anttila. Measurements of the recoil-ion response of silicon carbide detectors to fast neutrons / F. H. Ruddy, J. G. Seidel and F. Franceschini. Measurement of the neutron spectrum of the HB-4 cold source at the high flux isotope reactor at Oak Ridge National Laboratory / J. L. Robertson and E. B. Iverson. Feasibility of cavity ring-down laser spectroscopy for dose rate monitoring on nuclear reactor / H. Tomita ... [et al.]. Measuring transistor damage factors in a non-stable defect environment / D. B. King ... [et al.]. Neutron-detection based monitoring of void effects in boiling water reactors / J. Loberg ... [et al.] -- Poster session 1: Power reactor surveillance, retrospective dosimetry, benchmarks and inter-comparisons, adjustment methods, experimental techniques, transport calculations. Improved diagnostics for analysis of a reactor pulse radiation environment / S. M. Luker ... [et al.]. Simulation of the response of silicon carbide fast neutron detectors / F. Franceschini, F. H. Ruddy and B. Petrović. NSV A-3: a computer code for least-squares adjustment of neutron spectra and measured dosimeter responses / J. G

  6. Pathogenesis comparison between the United States porcine epidemic diarrhoea virus prototype and S-INDEL-variant strains in conventional neonatal piglets.

    PubMed

    Chen, Qi; Gauger, Phillip C; Stafne, Molly R; Thomas, Joseph T; Madson, Darin M; Huang, Haiyan; Zheng, Ying; Li, Ganwu; Zhang, Jianqiang

    2016-05-01

    At least two genetically different porcine epidemic diarrhoea virus (PEDV) strains have been identified in the USA: US PEDV prototype and S-INDEL-variant strains. The objective of this study was to compare the pathogenicity differences of the US PEDV prototype and S-INDEL-variant strains in conventional neonatal piglets under experimental infections. Fifty PEDV-negative 5-day-old pigs were divided into five groups of ten pigs each and were inoculated orogastrically with three US PEDV prototype isolates (IN19338/2013, NC35140/2013 and NC49469/2013), an S-INDEL-variant isolate (IL20697/2014), and virus-negative culture medium, respectively, with virus titres of 104 TCID50 ml- 1, 10 ml per pig. All three PEDV prototype isolates tested in this study, regardless of their phylogenetic clades, had similar pathogenicity and caused severe enteric disease in 5-day-old pigs as evidenced by clinical signs, faecal virus shedding, and gross and histopathological lesions. Compared with pigs inoculated with the three US PEDV prototype isolates, pigs inoculated with the S-INDEL-variant isolate had significantly diminished clinical signs, virus shedding in faeces, gross lesions in small intestines, caeca and colons, histopathological lesions in small intestines, and immunohistochemistry staining in ileum. However, the US PEDV prototype and the S-INDEL-variant strains induced similar viraemia levels in inoculated pigs. Whole genome sequences of the PEDV prototype and S-INDEL-variant strains were determined, but the molecular basis of virulence differences between these PEDV strains remains to be elucidated using a reverse genetics approach.

  7. Potentiation of C1-esterase inhibitor by heparin and interactions with C1s protease as assessed by surface plasmon resonance.

    PubMed

    Rajabi, Mohsen; Struble, Evi; Zhou, Zhaohua; Karnaukhova, Elena

    2012-01-01

    Human C1-esterase inhibitor (C1-INH) is a multifunctional plasma protein with a wide range of inhibitory and non-inhibitory properties, mainly recognized as a key down-regulator of the complement and contact cascades. The potentiation of C1-INH by heparin and other glycosaminoglycans (GAGs) regulates a broad spectrum of C1-INH activities in vivo both in normal and disease states. SCOPE OF RESEARCH: We have studied the potentiation of human C1-INH by heparin using Surface Plasmon Resonance (SPR), circular dichroism (CD) and a functional assay. To advance a SPR for multiple-unit interaction studies of C1-INH we have developed a novel (consecutive double capture) approach exploring different immobilization and layout. Our SPR experiments conducted in three different design versions showed marked acceleration in C1-INH interactions with complement protease C1s as a result of potentiation of C1-INH by heparin (from 5- to 11-fold increase of the association rate). Far-UV CD studies suggested that heparin binding did not alter C1-INH secondary structure. Functional assay using chromogenic substrate confirmed that heparin does not affect the amidolytic activity of C1s, but does accelerate its consumption due to C1-INH potentiation. This is the first report that directly demonstrates a significant acceleration of the C1-INH interactions with C1s due to heparin by using a consecutive double capture SPR approach. The results of this study may be useful for further C-INH therapeutic development, ultimately for the enhancement of current C1-INH replacement therapies. Published by Elsevier B.V.

  8. 10 CFR 32.102 - Schedule C-prototype tests for calibration or reference sources containing americium-241 or...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Schedule C-prototype tests for calibration or reference sources containing americium-241 or radium-226. 32.102 Section 32.102 Energy NUCLEAR REGULATORY COMMISSION SPECIFIC DOMESTIC LICENSES TO MANUFACTURE OR TRANSFER CERTAIN ITEMS CONTAINING BYPRODUCT MATERIAL Generally...

  9. SIMS prototype system 1 test results: Engineering analysis

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The space and domestic water solar heating system designated SIMS Prototype Systems 1 was evaluated. The test system used 720 ft (gross) of Solar Energy Products Air Collectors, a Solar Control Corporation SAM 20 Air Handler with Model 75-175 control unit, a Jackson Solar Storage tank with Rho Sigma Mod 106 controller, and 20 tons of rack storage. The test data analysis performed evaluates the system performance and documents the suitability of SIMS Prototype System 1 hardware for field installation.

  10. Assessment of Silicon Carbide Composites for Advanced Salt-Cooled Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Katoh, Yutai; Wilson, Dane F; Forsberg, Charles W

    2007-09-01

    The Advanced High-Temperature Reactor (AHTR) is a new reactor concept that uses a liquid fluoride salt coolant and a solid high-temperature fuel. Several alternative fuel types are being considered for this reactor. One set of fuel options is the use of pin-type fuel assemblies with silicon carbide (SiC) cladding. This report provides (1) an initial viability assessment of using SiC as fuel cladding and other in-core components of the AHTR, (2) the current status of SiC technology, and (3) recommendations on the path forward. Based on the analysis of requirements, continuous SiC fiber-reinforced, chemically vapor-infiltrated SiC matrix (CVI SiC/SiC) compositesmore » are recommended as the primary option for further study on AHTR fuel cladding among various industrially available forms of SiC. Critical feasibility issues for the SiC-based AHTR fuel cladding are identified to be (1) corrosion of SiC in the candidate liquid salts, (2) high dose neutron radiation effects, (3) static fatigue failure of SiC/SiC, (4) long-term radiation effects including irradiation creep and radiation-enhanced static fatigue, and (5) fabrication technology of hermetic wall and sealing end caps. Considering the results of the issues analysis and the prospects of ongoing SiC research and development in other nuclear programs, recommendations on the path forward is provided in the order or priority as: (1) thermodynamic analysis and experimental examination of SiC corrosion in the candidate liquid salts, (2) assessment of long-term mechanical integrity issues using prototypical component sections, and (3) assessment of high dose radiation effects relevant to the anticipated operating condition.« less

  11. Representations of Nets of C*-Algebras over S 1

    NASA Astrophysics Data System (ADS)

    Ruzzi, Giuseppe; Vasselli, Ezio

    2012-11-01

    In recent times a new kind of representations has been used to describe superselection sectors of the observable net over a curved spacetime, taking into account the effects of the fundamental group of the spacetime. Using this notion of representation, we prove that any net of C*-algebras over S 1 admits faithful representations, and when the net is covariant under Diff( S 1), it admits representations covariant under any amenable subgroup of Diff( S 1).

  12. Reactor performance and microbial community of an EGSB reactor operated at 20 and 15 degrees C.

    PubMed

    Xing, W; Zuo, J-E; Dai, N; Cheng, J; Li, J

    2009-09-01

    To investigate the effects of low temperatures on the performance and microbial community of anaerobic wastewater treatment. An expanded granular sludge bed (EGSB) reactor was employed to treat synthetic brewery wastewater at 20 and 15 degrees C. Reactor performance was represented by chemical oxygen demand (COD) removal efficiency, while the microbial community was analysed using denaturing gradient gel electrophoresis (DGGE) and clone technology. When the hydraulic retention time (HRT) was maintained at 18 h, COD removal efficiencies above 85% were obtained at both 20 and 15 degrees C, with influent COD concentrations up to 7300 and 4100 mg l(-1), respectively. At 15 degrees C, the COD removal efficiency was more easily manipulated by increasing the influent COD concentration. DGGE and clone results for both temperatures revealed that Methanosaeta and Methanobacterium were two dominant methanogens, and that the majority of the eubacterial clones were represented by Firmicutes. When the temperature decreased from 20 to 15 degrees C, both archaeal and eubacterial communities had higher diversity, and the proportion of Methanosaeta (acetate-utilizing methanogens) decreased markedly from 60.0% to 49.3%, together with an increase in proportions of hydrogen-utilizing methanogens (especially Methanospirillum). The feasibility of psychrophilic anaerobic treatment of low and medium strength organic wastewaters was demonstrated, although lower temperature could significantly affect both reactor performance and the anaerobic microbial community. The findings enrich the theory involving the microbial community and the application of anaerobic treatment in a psychrophilic environment.

  13. 48 CFR 215.403-1 - Prohibition on obtaining cost or pricing data (10 U.S.C. 2306a and 41 U.S.C. 254b).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... cost or pricing data (10 U.S.C. 2306a and 41 U.S.C. 254b). 215.403-1 Section 215.403-1 Federal... METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 215.403-1 Prohibition on obtaining cost or pricing data (10 U.S.C. 2306a and 41 U.S.C. 254b). (b) Exceptions to cost or pricing data...

  14. Application of the 1:2,000,000-scale data base: A National Atlas sectional prototype

    USGS Publications Warehouse

    Dixon, Donna M.

    1985-01-01

    A study of the potential to produce a National Atlas sectional prototype from the 1:2,000,000-scale data base was concluded recently by the National Mapping Division, U. S. Geological Survey. This paper discusses the specific digital cartographic production procedures involved in the preparation of the prototype map, as well as the theoretical and practical cartographic framework for the study. Such items as data organization, data classification, digital techniques, data conversions, and modification of traditional design specifications for an automated environment are discussed. The bulk of the cartographic work for the production of the prototype was carried out in raster format on the Scitex Response-250 mapping system.

  15. Heat Pipe Reactor Dynamic Response Tests: SAFE-100 Reactor Core Prototype

    NASA Technical Reports Server (NTRS)

    Bragg-Sitton, Shannon M.

    2005-01-01

    The SAFE-I00a test article at the NASA Marshall Space Flight Center was used to simulate a variety of potential reactor transients; the SAFEl00a is a resistively heated, stainless-steel heat-pipe (HP)-reactor core segment, coupled to a gas-flow heat exchanger (HX). For these transients the core power was controlled by a point kinetics model with reactivity feedback based on core average temperature; the neutron generation time and the temperature feedback coefficient are provided as model inputs. This type of non-nuclear test is expected to provide reasonable approximation of reactor transient behavior because reactivity feedback is very simple in a compact fast reactor (simple, negative, and relatively monotonic temperature feedback, caused mostly by thermal expansion) and calculations show there are no significant reactivity effects associated with fluid in the HP (the worth of the entire inventory of Na in the core is .

  16. U.S. Nuclear Cooperation with India: Issues for Congress

    DTIC Science & Technology

    2008-11-03

    separation list: ! 8 indigenous Indian power reactors ! Fast Breeder test Reactor (FTBR) and Prototype Fast Breeder Reactors (PFBR) under construction...facilities like reprocessing and enrichment plants and breeder reactors could be viewed as providing a significant nonproliferation benefit because the... breeder reactors would support the 2002 U.S. National Strategy to Combat Weapons of Mass Destruction, in which the United States pledged to “continue to

  17. U.S. Nuclear Cooperation with India: Issues for Congress

    DTIC Science & Technology

    2008-10-02

    8 indigenous Indian power reactors ! Fast Breeder test Reactor (FTBR) and Prototype Fast Breeder Reactors (PFBR) under construction ! Enrichment... breeder reactors could be viewed as providing a significant nonproliferation benefit because the materials produced by these plants are a few steps closer...to potential use in a bomb. In addition, safeguards on enrichment, reprocessing plants, and breeder reactors would support the 2002 U.S. National

  18. CO2 Reduction Assembly Prototype Using Microlith-Based Sabatier Reactor for Ground Demonstration

    NASA Technical Reports Server (NTRS)

    Junaedi, Christian; Hawley, Kyle; Walsh, Dennis; Roychoudhury, Subir; Abney, Morgan B.; Perry, Jay L.

    2014-01-01

    The utilization of CO2 to produce life support consumables, such as O2 and H2O, via the Sabatier reaction is an important aspect of NASA's cabin Atmosphere Revitalization System (ARS) and In-Situ Resource Utilization (ISRU) architectures for both low-earth orbit and long-term manned space missions. Carbon dioxide can be reacted with H2, obtained from the electrolysis of water, via Sabatier reaction to produce methane and H2O. Methane can be stored and utilized as propellant while H2O can be either stored or electrolyzed to produce oxygen and regain the hydrogen atoms. Depending on the application, O2 can be used to replenish the atmosphere in human-crewed missions or as an oxidant for robotic and return missions. Precision Combustion, Inc. (PCI), with support from NASA, has previously developed an efficient and compact Sabatier reactor based on its Microlith® catalytic technology and demonstrated the capability to achieve high CO2 conversion and CH4 selectivity (i.e., =90% of the thermodynamic equilibrium values) at high space velocities and low operating temperatures. This was made possible through the use of high-heat-transfer and high-surface-area Microlith catalytic substrates. Using this Sabatier reactor, PCI designed, developed, and demonstrated a stand-alone CO2 Reduction Assembly (CRA) test system for ground demonstration and performance validation. The Sabatier reactor was integrated with the necessary balance-of-plant components and controls system, allowing an automated, single "push-button" start-up and shutdown. Additionally, the versatility of the test system prototype was demonstrated by operating it under H2-rich (H2/CO2 of >4), stoichiometric (ratio of 4), and CO2-rich conditions (ratio of <4) without affecting its performance and meeting the equilibrium-predicted water recovery rates. In this paper, the development of the CRA test system for ground demonstration will be discussed. Additionally, the performance results from testing the system at

  19. Z-1 Prototype Space Suit Testing Summary

    NASA Technical Reports Server (NTRS)

    Ross, Amy

    2013-01-01

    The Advanced Space Suit team of the NASA-Johnson Space Center performed a series of test with the Z-1 prototype space suit in 2012. This paper discusses, at a summary level, the tests performed and results from those tests. The purpose of the tests were two-fold: 1) characterize the suit performance so that the data could be used in the downselection of components for the Z-2 Space Suit and 2) develop interfaces with the suitport and exploration vehicles through pressurized suit evaluations. Tests performed included isolated and functional range of motion data capture, Z-1 waist and hip testing, joint torque testing, CO2 washout testing, fit checks and subject familiarizations, an exploration vehicle aft deck and suitport controls interface evaluation, delta pressure suitport tests including pressurized suit don and doff, and gross mobility and suitport ingress and egress demonstrations in reduced gravity. Lessons learned specific to the Z-1 prototype and to suit testing techniques will be presented.

  20. Z-1 Prototype Space Suit Testing Summary

    NASA Technical Reports Server (NTRS)

    Ross, Amy J.

    2012-01-01

    The Advanced Space Suit team of the NASA-Johnson Space Center performed a series of test with the Z-1 prototype space suit in 2012. This paper discusses, at a summary level, the tests performed and results from those tests. The purpose of the tests were two -fold: 1) characterize the suit performance so that the data could be used in the downselection of components for the Z -2 Space Suit and 2) develop interfaces with the suitport and exploration vehicles through pressurized suit evaluations. Tests performed included isolated and functional range of motion data capture, Z-1 waist and hip testing, joint torque testing, CO2 washout testing, fit checks and subject familiarizations, an exploration vehicle aft deck and suitport controls interface evaluation, delta pressure suitport tests including pressurized suit don and doff, and gross mobility and suitport ingress and egress demonstrations in reduced gravity. Lessons learned specific to the Z -1 prototype and to suit testing techniques will be presented.

  1. U.S. Nuclear Cooperation with India: Issues for Congress

    DTIC Science & Technology

    2008-10-17

    safeguards-irrelevant.” The following facilities and activities were not on the separation list: ! 8 indigenous Indian power reactors ! Fast Breeder ...test Reactor (FTBR) and Prototype Fast Breeder Reactors (PFBR) under construction ! Enrichment facilities ! Spent fuel reprocessing facilities (except...potential use in a bomb. In addition, safeguards on enrichment, reprocessing plants, and breeder reactors would support the 2002 U.S. National Strategy to

  2. Graphite distortion ``C`` Reactor. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wood, N.H.

    1962-02-08

    This report covers the efforts of the Laboratory in an investigation of the graphite distortion in the ``C`` reactor at Hanford. The particular aspects of the problem to be covered by the Laboratory were possible ``fixes`` to the control rod sticking problem caused by VSR channel distortion.

  3. Space reactor fuel element testing in upgraded TREAT

    NASA Astrophysics Data System (ADS)

    Todosow, M.; Bezler, P.; Ludewig, H.; Kato, W. Y.

    The testing of candidate fuel elements at prototypic operating conditions with respect to temperature, power density, hydrogen coolant flow rate, etc.; a crucial component in the development and qualification of nuclear rocket engines based on the Particle Bed Reactor (PBR); NERVA-derivative; and other concepts are discussed. Such testing may be performed at existing reactors, or at new facilities. A scoping study has been performed to assess the feasibility of testing PBR based fuel elements at the TREAT reactor. Initial results suggest that full-scale PBR elements could be tested at an average energy deposition of approximately 60-80 MW-s/L in the current TREAT reactor. If the TREAT reactor was upgraded to include fuel elements with a higher temperature limit, average energy deposition of approximately 100 MW/L may be achievable.

  4. Space reactor fuel element testing in upgraded TREAT

    NASA Astrophysics Data System (ADS)

    Todosow, Michael; Bezler, Paul; Ludewig, Hans; Kato, Walter Y.

    1993-01-01

    The testing of candidate fuel elements at prototypic operating conditions with respect to temperature, power density, hydrogen coolant flow rate, etc., is a crucial component in the development and qualification of nuclear rocket engines based on the Particle Bed Reactor (PBR), NERVA-derivative, and other concepts. Such testing may be performed at existing reactors, or at new facilities. A scoping study has been performed to assess the feasibility of testing PBR based fuel elements at the TREAT reactor. Initial results suggests that full-scale PBR elements could be tested at an average energy deposition of ˜60-80 MW-s/L in the current TREAT reactor. If the TREAT reactor was upgraded to include fuel elements with a higher temperture limit, average energy deposition of ˜100 MW/L may be achievable.

  5. Irradiation Microstructure of Austenitic Steels and Cast Steels Irradiated in the BOR-60 Reactor at 320°C

    NASA Astrophysics Data System (ADS)

    Yang, Yong; Chen, Yiren; Huang, Yina; Allen, Todd; Rao, Appajosula

    Reactor internal components are subjected to neutron irradiation in light water reactors, and with the aging of nuclear power plants around the world, irradiation-induced material degradations are of concern for reactor internals. Irradiation-induced defects resulting from displacement damage are critical for understanding degradation in structural materials. In the present work, microstructural changes due to irradiation in austenitic stainless steels and cast steels were characterized using transmission electron microscopy. The specimens were irradiated in the BOR-60 reactor, a fast breeder reactor, up to 40 dpa at 320°C. The dose rate was approximately 9.4x10-7 dpa/s. Void swelling and irradiation defects were analyzed for these specimens. A high density of faulted loops dominated the irradiated-altered microstructures. Along with previous TEM results, a dose dependence of the defect structure was established at 320°C.

  6. 46. C.P.S., photographer March 1936 MENDOCINO COUNTY, SECTION, HIGHWAY 1. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. C.P.S., photographer March 1936 MENDOCINO COUNTY, SECTION, HIGHWAY 1. MEN-1-J#135, 384+50 81TTC2, LOOKING SOUTH LANES FLAT, C.P.S., 36. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  7. 14C content in vegetation in the vicinities of Brazilian nuclear power reactors.

    PubMed

    Dias, Cíntia Melazo; Santos, Roberto Ventura; Stenström, Kristina; Nícoli, Iêda Gomes; Skog, Göran; da Silveira Corrêa, Rosangela

    2008-07-01

    (14)C specific activities were measured in grass samples collected around Brazilian nuclear power reactors. The specific activity values varied between 227 and 299 Bq/kg C. Except for two samples which showed (14)C specific activities 22% above background values, half of the samples showed background specific activities, and the other half had a (14)C excess of 1-18%. The highest specific activities were found close to the nuclear power plants and along the main wind directions (NE and NNE). The activity values were found to decrease with increasing distance from the reactors. The unexpectedly high (14)C excess values found in two samples were related to the local topography, which favors (14)C accumulation and limits the dispersion of the plume. The results indicate a clear (14)C anthropogenic signal within 5 km around the nuclear power plants which is most prominent along northeastwards, the prevailing wind direction.

  8. 45. C.P.S., photographer January 1936 MENDOCINO COUNTY, SECTION, HIGHWAY 1. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    45. C.P.S., photographer January 1936 MENDOCINO COUNTY, SECTION, HIGHWAY 1. MEN-I-J #132, 388+00 81TTC2, LOOKING SOUTH LANES FLAT, C.P.S., 1-36. - Redwood National & State Parks Roads, California coast from Crescent City to Trinidad, Crescent City, Del Norte County, CA

  9. Nitrifying moving bed biofilm reactor (MBBR) biofilm and biomass response to long term exposure to 1 °C.

    PubMed

    Hoang, V; Delatolla, R; Abujamel, T; Mottawea, W; Gadbois, A; Laflamme, E; Stintzi, A

    2014-02-01

    This study aims to investigate moving bed biofilm reactor (MBBR) nitrification rates, nitrifying biofilm morphology, biomass viability as well as bacterial community shifts during long-term exposure to 1 °C. Long-term exposure to 1 °C is the key operational condition for potential ammonia removal upgrade units to numerous northern region treatment systems. The average laboratory MBBR ammonia removal rate after long-term exposure to 1 °C was measured to be 18 ± 5.1% as compared to the average removal rate at 20 °C. Biofilm morphology and specifically the thickness along with biomass viability at various depths in the biofilm were investigated using variable pressure electron scanning microscope (VPSEM) imaging and confocal laser scanning microscope (CLSM) imaging in combination with viability live/dead staining. The biofilm thickness along with the number of viable cells showed significant increases after long-term exposure to 1 °C. Hence, this study observed nitrifying bacteria with higher activities at warm temperatures and a slightly greater quantity of nitrifying bacteria with lower activities at cold temperatures in nitrifying MBBR biofilms. Using DNA sequencing analysis, Nitrosomonas and Nitrosospira (ammonia oxidizers) as well as Nitrospira (nitrite oxidizer) were identified and no population shift was observed between 20 °C and after long-term exposure to 1 °C. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. 75 FR 82094 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR); Notice of Meeting The ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR) will hold a meeting on January 12, 2011, Room T-2B1, 11545 Rockville Pike...

  11. 77 FR 74697 - Meeting of the ACRS, Subcommittee on U.S. Evolutionary Power Reactor; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS, Subcommittee on U.S. Evolutionary Power Reactor; Notice of Meeting The ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR) will hold a meeting on January 17, 2013, Room T-2B1, 11545 Rockville Pike...

  12. Far-Ultraviolet Observations of Comet C 2012 S1 (ISON) From Fortis

    NASA Technical Reports Server (NTRS)

    Mccandiss, Stephan R.; Feldman, Paul D.; Weaver, Harold; Fleming, Brian; Redwine, Keith; Li, Mary J.; Kutyrev, Alexander; Moseley, S. Harvey

    2016-01-01

    We have used the unique far-UV imaging capability offered by a sounding-rocket-borne instrument to acquire observations of C/2012 S1 (ISON) when its angular separation with respect to the Sun was 26 deg.3 on 2013 November 20.49. At the time of observation, the comet's heliocentric distance and velocity relative to the Sun were r h = 0.43 au and r (sub h) = 62.7 km s)exp. -1). Images dominated by C Iota Lambda 1657 and H Iota Lambda 1216 were acquired over a 10(exp. 6) x 10(exp. 6) km(exp. 2) region. The water production rate implied by the Ly Alpha observations is constrained to be Q H2O is much greater than 8 x 10(exp. 29) s(exp. -1) while the neutral carbon production rate was Q(sub c) is much greater than 4 x 10(exp. 28) s(exp. -1). The radial profile of C I was consistent with it being a dissociation product of a parent molecule with a lifetime T is approx. 5 x 10(exp. 4) s, favoring a parent other than CO. We constrain the Q(sub co) production rate to 5(+1.5)(-7.5), 10(exp. 28) s(exp. -1) with 1 sigma errors derived from photon statistics. The upper limit on the Q (sub CO)/Q(sub H2O) is 6%.

  13. U.S., European ALMA Partners Award Prototype Antenna Contracts

    NASA Astrophysics Data System (ADS)

    2000-03-01

    The U.S. and European partners in the Atacama Large Millimeter Array (ALMA) project have awarded contracts to U.S. and Italian firms, respectively, for two prototype antennas. ALMA is a planned telescope array, expected to consist of 64 millimeter-wave antennas with 12-meter diameter dishes. The array will be built at a high-altitude, extremely dry mountain site in Chile's Atacama desert, and is scheduled to be completed sometime in this decade. On February 22, 2000, Associated Universities Inc. (AUI) signed an approximately $6.2 million contract with Vertex Antenna Systems, of Santa Clara, Calif., for construction of one prototype ALMA antenna. AUI operates the U.S. National Radio Astronomy Observatory (NRAO) for the National Science Foundation under a cooperative agreement. The European partners contracted with the consortium of European Industrial Engineering and Costamasnaga, of Mestre, Italy, on February 21, 2000, for the production of another prototype. (Mestre is located on the inland side of Venice.) The two antennas must meet identical specifications, but will inherently be of different designs. This will ensure that the best possible technologies are incorporated into the final production antennas. Only one of the designs will be selected for final production. Several technical challenges must be met for the antennas to perform to ALMA specifications. Each antenna must have extremely high surface accuracy (25 micrometers, or one-third the diameter of a human hair, over the entire 12-meter diameter). This means that, when completed, the surface accuracy of the ALMA dishes will be 20 times greater than that of the Very Large Array (VLA) antennas, and about 50 times greater than dish antennas for communications or radar. The ALMA antennas must also have extremely high pointing accuracy (0.6 arcseconds). An additional challenge is that the antennas, when installed at the ALMA site in Chile, will be exposed to the ravages of weather at 16,500 feet (5000 meters

  14. Prototype for Meta-Algorithmic, Content-Aware Image Analysis

    DTIC Science & Technology

    2015-03-01

    PROTOTYPE FOR META-ALGORITHMIC, CONTENT-AWARE IMAGE ANALYSIS UNIVERSITY OF VIRGINIA MARCH 2015 FINAL TECHNICAL REPORT...ALGORITHMIC, CONTENT-AWARE IMAGE ANALYSIS 5a. CONTRACT NUMBER FA8750-12-C-0181 5b. GRANT NUMBER N/A 5c. PROGRAM ELEMENT NUMBER 62305E 6. AUTHOR(S) S...approaches were studied in detail and their results on a sample dataset are presented. 15. SUBJECT TERMS Image Analysis , Computer Vision, Content

  15. Space reactor fuel element testing in upgraded TREAT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Todosow, M.; Bezler, P.; Ludewig, H.

    1993-01-14

    The testing of candidate fuel elements at prototypic operating conditions with respect to temperature, power density, hydrogen coolant flow rate, etc., a crucial component in the development and qualification of nuclear rocket engines based on the Particle Bed Reactor (PBR), NERVA-derivative, and other concepts. Such testing may be performed at existing reactors, or at new facilities. A scoping study has been performed to assess the feasibility of testing PBR based fuel elements at the TREAT reactor. initial results suggest that full-scale PBR, elements could be tested at an average energy deposition of {approximately}60--80 MW-s/L in the current TREAT reactor. Ifmore » the TREAT reactor was upgraded to include fuel elements with a higher temperature limit, average energy deposition of {approximately}100 MW/L may be achievable.« less

  16. Space reactor fuel element testing in upgraded TREAT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Todosow, M.; Bezler, P.; Ludewig, H.

    1993-05-01

    The testing of candidate fuel elements at prototypic operating conditions with respect to temperature, power density, hydrogen coolant flow rate, etc., a crucial component in the development and qualification of nuclear rocket engines based on the Particle Bed Reactor (PBR), NERVA-derivative, and other concepts. Such testing may be performed at existing reactors, or at new facilities. A scoping study has been performed to assess the feasibility of testing PBR based fuel elements at the TREAT reactor. initial results suggest that full-scale PBR, elements could be tested at an average energy deposition of {approximately}60--80 MW-s/L in the current TREAT reactor. Ifmore » the TREAT reactor was upgraded to include fuel elements with a higher temperature limit, average energy deposition of {approximately}100 MW/L may be achievable.« less

  17. 32 CFR 37.105 - Does this part cover all types of instruments that 10 U.S.C. 2371 authorizes?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... covers only TIAs, some of which use the authority of 10 U.S.C. 2371 (see appendix B to this part). This part does not cover assistance instruments other than TIAs that use the authority of 10 U.S.C. 2371. It also does not cover acquisition agreements for prototype projects that use 10 U.S.C. 2371 authority...

  18. 11 CFR 101.1 - Candidate designations (2 U.S.C. 432(e)(1)).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Candidate designations (2 U.S.C. 432(e)(1)). 101.1 Section 101.1 Federal Elections FEDERAL ELECTION COMMISSION GENERAL CANDIDATE STATUS AND... and address, party affiliation, and office sought, the District and State in which Federal office is...

  19. Design and Beam Test Results for the sPHENIX Electromagnetic and Hadronic Calorimeter Prototypes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aidala, C.A.; et al.

    The sPHENIX experiment at the Relativistic Heavy Ion Collider (RHIC) will perform high precision measurements of jets and heavy flavor observables for a wide selection of nuclear collision systems, elucidating the microscopic nature of strongly interacting matter ranging from nucleons to the strongly coupled quark-gluon plasma. A prototype of the sPHENIX calorimeter system was tested at the Fermilab Test Beam Facility as experiment T-1044 in the spring of 2016. The electromagnetic calorimeter (EMCal) prototype is composed of scintillating fibers embedded in a mixture of tungsten powder and epoxy. The hadronic calorimeter (HCal) prototype is composed of tilted steel plates alternating with plastic scintillator. Results of the test beam reveal the energy resolution for electrons in the EMCal ismore » $$2.8\\%\\oplus~15.5\\%/\\sqrt{E}$$ and the energy resolution for hadrons in the combined EMCal plus HCal system is $$13.5\\%\\oplus 64.9\\%/\\sqrt{E}$$. These results demonstrate that the performance of the proposed calorimeter system is consistent with \\geant simulations and satisfies the sPHENIX specifications.« less

  20. Prototypes and system test stands for the Phase 1 upgrade of the CMS pixel detector

    DOE PAGES

    Hasegawa, S.

    2016-04-23

    The CMS pixel phase-1 upgrade project replaces the current pixel detector with an upgraded system with faster readout electronics during the extended year-end technical stop of 2016/2017. New electronics prototypes for the system have been developed, and tests in a realistic environment for a comprehensive evaluation are needed. A full readout test stand with either the same hardware as used in the current CMS pixel detector or the latest prototypes of upgrade electronics has been built. The setup enables the observation and investigation of a jitter increase in the data line associated with trigger rate increases. This effect is duemore » to the way in which the clock and trigger distribution is implemented in CMS. A new prototype of the electronics with a PLL based on a voltage controlled quartz crystal oscillator (QPLL), which works as jitter filter, in the clock distribution path was produced. With the test stand, it was confirmed that the jitter increase is not seen with the prototype, and also good performance was confirmed at the expected detector operation temperature ($-$20 °C).« less

  1. Coma Morphology of Recent Comets: C/ISON (2012 S1), C/Pan-STARRS (2012 K1), C/Jacques (2014 E2), and C/Siding Spring (2013 A1)

    NASA Astrophysics Data System (ADS)

    Knight, Matthew M.; Schleicher, David G.

    2014-11-01

    We will present preliminary results from recent and upcoming imaging campaigns of four comets using Lowell Observatory’s 4.3-m Discovery Channel Telescope, 42-in Hall Telescope, and/or 31-in telescope: 1. Observations of C/ISON (2012 S1) were carried out from January through November 2013. A small, sunward fan was detected in dust images acquired in March, April, May, and September. Two faint CN features approximately orthogonal to the tail appeared on November 1 and were visible until our final night of data on November 12. This significantly predates their first reported appearance in broadband images on November 14 (Boehnhard et al., CBET 3715; Ye et al., CBET 3718) and suggests that the features were not caused by a catastrophic disruption of the nucleus at that time.2. We observed C/Pan-STARRS (2012 K1) regularly from October 2013 through June 2014 when it entered solar conjunction. Enhanced CN images in May and June 2014 exhibited a side-on pinwheel morphology that varied from night to night; similar morphology was not seen in concurrent dust images. Analysis of the rotation period is underway. 3. C/Jacques (2014 E2) was observed in April, May, and August 2014, and additional observations are scheduled through September 2014. After enhancement of the August images, Jacques exhibited two side-on CN corkscrews roughly orthogonal to the tail. The CN morphology was different from night to night but did not vary noticeably during ~1 hr of observations on a given night. Jacques also exhibited a smaller sunward dust feature in August that did not appear to vary during the observations. We will combine these data with our scheduled observations to investigate periodicity and compare the spatial distribution of multiple gas species. 4. Observations of C/Siding Spring (2013 A1) are scheduled around its close approach to Mars on October 19, 2014. This work is supported by NASA’s Planetary Astronomy Program grants NNX09AB51G and NNX11AD95G.

  2. Measurement of sigma chi c2 B(chi c2-->J/psi gamma)/sigma chi c1 B(chi c1 -->J/psi gamma) in pp collisions at square root s=1.96 TeV.

    PubMed

    Abulencia, A; Adelman, J; Affolder, T; Akimoto, T; Albrow, M G; Ambrose, D; Amerio, S; Amidei, D; Anastassov, A; Anikeev, K; Annovi, A; Antos, J; Aoki, M; Apollinari, G; Arguin, J-F; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Azfar, F; Azzi-Bacchetta, P; Azzurri, P; Bacchetta, N; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Baroiant, S; Bartsch, V; Bauer, G; Bedeschi, F; Behari, S; Belforte, S; Bellettini, G; Bellinger, J; Belloni, A; Benjamin, D; Beretvas, A; Beringer, J; Berry, T; Bhatti, A; Binkley, M; Bisello, D; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bolshov, A; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Budroni, S; Burkett, K; Busetto, G; Bussey, P; Byrum, K L; Cabrera, S; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carillo, S; Carlsmith, D; Carosi, R; Carron, S; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, I; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Ciljak, M; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Coca, M; Compostella, G; Convery, M E; Conway, J; Cooper, B; Copic, K; Cordelli, M; Cortiana, G; Crescioli, F; Cuenca Almenar, C; Cuevas, J; Culbertson, R; Cully, J C; Cyr, D; DaRonco, S; Datta, M; D'Auria, S; Davies, T; D'Onofrio, M; Dagenhart, D; de Barbaro, P; De Cecco, S; Deisher, A; De Lentdecker, G; Dell'Orso, M; Delli Paoli, F; Demortier, L; Deng, J; Deninno, M; De Pedis, D; Derwent, P F; Di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; DiTuro, P; Dörr, C; Donati, S; Donega, M; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, I; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Field, R; Flanagan, G; Foland, A; Forrester, S; Foster, G W; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garcia, J E; Garberson, F; Garfinkel, A F; Gay, C; Gerberich, H; Gerdes, D; Giagu, S; Giannetti, P; Gibson, A; Gibson, K; Gimmell, J L; Ginsburg, C; Giokaris, N; Giordani, M; Giromini, P; Giunta, M; Giurgiu, G; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Goldstein, J; Golossanov, A; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Griffiths, M; Grinstein, S; Grosso-Pilcher, C; Group, R C; Grundler, U; Guimaraes da Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, K; Hahn, S R; Halkiadakis, E; Hamilton, A; Han, B-Y; Han, J Y; Handler, R; Happacher, F; Hara, K; Hare, M; Harper, S; Harr, R F; Harris, R M; Hartz, M; Hatakeyama, K; Hauser, J; Heijboer, A; Heinemann, B; Heinrich, J; Henderson, C; Herndon, M; Heuser, J; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Holloway, A; Hou, S; Houlden, M; Hsu, S-C; Huffman, B T; Hughes, R E; Husemann, U; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ishizawa, Y; Ivanov, A; Iyutin, B; James, E; Jang, D; Jayatilaka, B; Jeans, D; Jensen, H; Jeon, E J; Jindariani, S; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Karchin, P E; Kato, Y; Kemp, Y; Kephart, R; Kerzel, U; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Klute, M; Knuteson, B; Ko, B R; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kovalev, A; Kraan, A C; Kraus, J; Kravchenko, I; Kreps, M; Kroll, J; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhlmann, S E; Kuhr, T; Kusakabe, Y; Kwang, S; Laasanen, A T; Lai, S; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; LeCompte, T; Lee, J; Lee, J; Lee, Y J; Lee, S W; Lefèvre, R; Leonardo, N; Leone, S; Levy, S; Lewis, J D; Lin, C; Lin, C S; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Loverre, P; Lu, R-S; Lucchesi, D; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Lytken, E; Mack, P; MacQueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Manca, G; Margaroli, F; Marginean, R; Marino, C; Marino, C P; Martin, A; Martin, M; Martin, V; Martínez, M; Maruyama, T; Mastrandrea, P; Masubuchi, T; Matsunaga, H; Mattson, M E; Mazini, R; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzemer, S; Menzione, A; Merkel, P; Mesropian, C; Messina, A; Miao, T; Miladinovic, N; Miles, J; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyamoto, A; Moed, S; Moggi, N; Mohr, B; Moore, R; Morello, M; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Nachtman, J; Nagano, A; Naganoma, J; Nakano, I; Napier, A; Necula, V; Neu, C; Neubauer, M S; Nielsen, J; Nigmanov, T; Nodulman, L; Norniella, O; Nurse, E; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Oldeman, R; Orava, R; Osterberg, K; Pagliarone, C; Palencia, E; Papadimitriou, V; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Piedra, J; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Portell, X; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ranjan, N; Rappoccio, S; Reisert, B; Rekovic, V; Renton, P; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Ruiz, A; Russ, J; Rusu, V; Saarikko, H; Sabik, S; Safonov, A; Sakumoto, W K; Salamanna, G; Saltó, O; Saltzberg, D; Sánchez, C; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savard, P; Savoy-Navarro, A; Scheidle, T; Schlabach, P; Schmidt, E E; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scott, A L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sfyrla, A; Shapiro, M D; Shears, T; Shepard, P F; Sherman, D; Shimojima, M; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Sinervo, P; Sisakyan, A; Sjolin, J; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soderberg, M; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spinella, F; Spreitzer, T; Squillacioti, P; Stanitzki, M; Staveris-Polykalas, A; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Stuart, D; Suh, J S; Sukhanov, A; Sun, H; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Takikawa, K; Tanaka, M; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thom, J; Thompson, A S; Thomson, E; Tipton, P; Tiwari, V; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Tourneur, S; Trischuk, W; Tsuchiya, R; Tsuno, S; Turini, N; Ukegawa, F; Unverhau, T; Uozumi, S; Usynin, D; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Veramendi, G; Veszpremi, V; Vidal, R; Vila, I; Vilar, R; Vine, T; Vollrath, I; Volobouev, I; Volpi, G; Würthwein, F; Wagner, P; Wagner, R G; Wagner, R L; Wagner, J; Wagner, W; Wallny, R; Wang, S M; Warburton, A; Waschke, S; Waters, D; Weinberger, M; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zhang, X; Zhou, J; Zucchelli, S

    2007-06-08

    We measure the ratio of cross section times branching fraction, Rp=sigma chi c2 B(chi c2-->J/psi gamma)/sigma chi c1 B(chi c1-->J/psi gamma), in 1.1 fb(-1) of pp collisions at square root s=1.96 TeV. This measurement covers the kinematic range pT(J/psi)>4.0 GeV/c, |eta(J/psi)<1.0, and pT(gamma)>1.0 GeV/c. For events due to prompt processes, we find Rp=0.395+/-0.016(stat)+/-0.015(syst). This result represents a significant improvement in precision over previous measurements of prompt chi c1,2 hadro production.

  3. Advance High Temperature Inspection Capabilities for Small Modular Reactors: Part 1 - Ultrasonics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bond, Leonard J.; Bowler, John R.

    The project objective was to investigate the development non-destructive evaluation techniques for advanced small modular reactors (aSMR), where the research sought to provide key enabling inspection technologies needed to support the design and maintenance of reactor component performance. The project tasks for the development of inspection techniques to be applied to small modular reactor are being addressed through two related activities. The first is focused on high temperature ultrasonic transducers development (this report Part 1) and the second is focused on an advanced eddy current inspection capability (Part 2). For both inspection techniques the primary aim is to develop in-servicemore » inspection techniques that can be carried out under standby condition in a fast reactor at a temperature of approximately 250°C in the presence of liquid sodium. The piezoelectric material and the bonding between layers have been recognized as key factors fundamental for development of robust ultrasonic transducers. Dielectric constant characterization of bismuth scantanate-lead titanate ((1-x)BiScO 3-xPbTiO 3) (BS-PT) has shown a high Curie temperature in excess of 450°C , suitable for hot stand-by inspection in liquid metal reactors. High temperature pulse-echo contact measurements have been performed with BS-PT bonded to 12.5 mm thick 1018-low carbon steel plate from 20C up to 260 C. High temperature air-backed immersion transducers have been developed with BS-PT, high temperature epoxy and quarter wavlength nickel plate, needed for wetting ability in liquid sodium. Ultrasonic immersion measurements have been performed in water up to 92C and in silicone oil up to 140C. Physics based models have been validated with room temperature experimental data with benchmark artifical defects.« less

  4. Courthouse Prototype Building

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Malhotra, Mini; New, Joshua Ryan; Im, Piljae

    As part of DOE's support of ANSI/ASHRAE/IES Standard 90.1 and IECC, researchers at Pacific Northwest National Laboratory (PNNL) apply a suite of prototype buildings covering 80% of the commercial building floor area in the U.S. for new construction. Efforts have started on expanding the prototype building suite to cover 90% of the commercial building floor area in the U.S., by developing prototype models for additional building types including place of worship, public order and safety, public assembly. Courthouse is courthouse is a sub-category under the “Public Order and Safety" building type category; other sub-categories include police station, fire station, andmore » jail, reformatory or penitentiary.ORNL used building design guides, databases, and documented courthouse projects, supplemented by personal communication with courthouse facility planning and design experts, to systematically conduct research on the courthouse building and system characteristics. This report documents the research conducted for the courthouse building type and proposes building and system characteristics for developing a prototype building energy model to be included in the Commercial Building Prototype Model suite. According to the 2012 CBECS, courthouses occupy a total of 436 million sqft of floor space or 0.5% of the total floor space in all commercial buildings in the US, next to fast food (0.35%), grocery store or food market (0.88%), and restaurant or cafeteria (1.2%) building types currently included in the Commercial Prototype Building Model suite. Considering aggregated average, courthouse falls among the larger with a mean floor area of 69,400 sqft smaller fuel consumption intensity building types and an average of 94.7 kBtu/sqft compared to 77.8 kBtu/sqft for office and 80 kBtu/sqft for all commercial buildings.Courthouses range in size from 1000 sqft to over a million square foot building gross square feet and 1 courtroom to over 100 courtrooms. Small courthouses

  5. Station Blackout Analysis of HTGR-Type Experimental Power Reactor

    NASA Astrophysics Data System (ADS)

    Syarip; Zuhdi, Aliq; Falah, Sabilul

    2018-01-01

    The National Nuclear Energy Agency of Indonesia has decided to build an experimental power reactor of high-temperature gas-cooled reactor (HTGR) type located at Puspiptek Complex. The purpose of this project is to demonstrate a small modular nuclear power plant that can be operated safely. One of the reactor safety characteristics is the reliability of the reactor to the station blackout (SBO) event. The event was observed due to relatively high disturbance frequency of electricity network in Indonesia. The PCTRAN-HTR functional simulator code was used to observe fuel and coolant temperature, and coolant pressure during the SBO event. The reactor simulated at 10 MW for 7200 s then the SBO occurred for 1-3 minutes. The analysis result shows that the reactor power decreases automatically as the temperature increase during SBO accident without operator’s active action. The fuel temperature increased by 36.57 °C every minute during SBO and the power decreased by 0.069 MW every °C fuel temperature rise at the condition of anticipated transient without reactor scram. Whilst, the maximum coolant (helium) temperature and pressure are 1004 °C and 9.2 MPa respectively. The maximum fuel temperature is 1282 °C, this value still far below the fuel temperature limiting condition i.e. 1600 °C, its mean that the HTGR has a very good inherent safety system.

  6. Post-irradiation examination of prototype Al-64 wt% U{sub 3}Si{sub 2} fuel rods from NRU

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sears, D.F.; Primeau, M.F.; Buchanan, C.

    1997-08-01

    Three prototype fuel rods containing Al-64 wt% U{sub 3}Si{sub 2} (3.15 gU/cm{sup 3}) have been irradiated to their design burnup in the NRU reactor without incident. The fuel was fabricated using production-scale equipment and processes previously developed for Al-U{sub 3}Si fuel fabrication at Chalk River Laboratories, and special equipment developed for U{sub 3}Si{sub 2} powder production and handling. The rods were irradiated in NRU up to 87 at% U-235 burnup under typical driver fuel conditions; i.e., nominal coolant inlet temperature 37{degrees}C, inlet pressure 654 kPa, mass flow 12.4 L/s, and element linear power ratings up to 73 kW/m. Post-irradiation examinationsmore » showed that the fuel elements survived the irradiation without defects. Fuel core diametral increases and volumetric swelling were significantly lower than that of Al-61 wt% U{sub 3}Si fuel irradiated under similar conditions. This irradiation demonstrated that the fabrication techniques are adequate for full-scale fuel manufacture, and qualified the fuel for use in AECL`s research reactors.« less

  7. Performance Characterization of a Prototype Ultra-Short Channel Monolith Catalytic Reactor for Air Quality Control Applications

    NASA Technical Reports Server (NTRS)

    Perry, J. L.; Tomes, K. M.; Roychoudhury, S.; Tatara, J. D.

    2005-01-01

    Contaminated air and process gases, whether in a crewed spacecraft cabin atmosphere, the working volume of a microgravity science or ground-based laboratory experiment facility, or the exhaust from an automobile, are pervasive problems that ultimately effect human health, performance, and well-being. The need for highly-effective, economical decontamination processes spans a wide range of terrestrial and space flight applications. Adsorption processes are used widely for process gas decontamination. Most industrial packed bed adsorption processes use activated carbon because it is cheap and highly effective. Once saturated, however, the adsorbent is a concentrated source of contaminants. Industrial applications either dump or regenerate the activated carbon. Regeneration may be accomplished in-situ or at an off-site location. In either case, concentrated contaminated waste streams must be handled appropriately to minimize environmental impact. As economic and regulatory forces drive toward minimizing waste and environmental impact, thermal catalytic oxidation is becoming more attractive. Through novel reactor and catalyst design, more complete contaminant destruction and greater resistance to poisoning can achieved leading to less waste handling, process down-time, and maintenance. Performance of a prototype thermal catalytic reactor, based on ultra-short channel monolith (USCM) catalyst substrate design, under a variety of process flow and contaminant loading conditions is discussed. The experimental results are evaluated against present and future air quality control and process gas purification processes used on board crewed spacecraft.

  8. Molecular characterization of a novel proto-type antimicrobial protein galectin-1 from striped murrel.

    PubMed

    Arasu, Abirami; Kumaresan, Venkatesh; Sathyamoorthi, Akila; Chaurasia, Mukesh Kumar; Bhatt, Prasanth; Gnanam, Annie J; Palanisamy, Rajesh; Marimuthu, Kasi; Pasupuleti, Mukesh; Arockiaraj, Jesu

    2014-11-01

    In this study, we reported a molecular characterization of a novel proto-type galectin-1 from the striped murrel Channa striatus (named as CsGal-1). The full length CsGal-1 was identified from an established striped murrel cDNA library and further we confirmed the sequence by cloning. The complete cDNA sequence of CsGal-1 is 590 base pairs (bp) in length and its coding region encoded a poly peptide of 135 amino acids. The polypeptide contains a galactoside binding lectin domain at 4-135. The domain carries a sugar binding site at 45-74 along with its signatures (H(45)-X-Asn(47)-X-Arg(49) and Trp(69)-X-X-Glu(72)-X-Arg(74)). CsGal-1 shares a highly conserved carbohydrate recognition domain (CRD) with galectin-1 from other proto-type galectin of teleosts. The mRNA expressions of CsGal-1 in healthy and various immune stimulants including Aphanomyces invadans, Aeromonas hydrophila, Escherchia coli lipopolysaccharide and poly I:C injected tissues of C. striatus were examined using qRT-PCR. CsGal-1 mRNA is highly expressed in kidney and is up-regulated with different immune stimulants at various time points. To understand its biological activity, the coding region of CsGal-1 gene was expressed in an E. coli BL21 (DE3) cloning system and its recombinant protein was purified. The recombinant CsGal-1 protein was agglutinated with mouse erythrocytes at a concentration of 4μg/mL in a calcium independent manner. CsGal-1 activity was inhibited by d-galactose at 25mM(-1) and d-glucose and d-fructose at 100mM(-1). The results of microbial binding assay showed that the recombinant CsGal-1 protein agglutinated only with the Gram-negative bacteria. Interestingly, we observed no agglutination against Gram-positive bacteria. Overall, the study showed that CsGal-1 is an important immune gene involved in the recognition and elimination of pathogens in C. striatus. Copyright © 2014 Elsevier GmbH. All rights reserved.

  9. EO-1 Prototyping for Environmental Applications

    NASA Astrophysics Data System (ADS)

    Campbell, P. K.; Middleton, E.; Ungar, S.; Zhang, Q.; Ong, L.; Huemmrich, K. F.

    2009-12-01

    The Earth Observing One (EO-1) Mission, launched in November, 2000 as part of NASA’s New Millennium Program, is in it’s eight year of operation. From the start it was recognized that a key criteria for evaluating the EO-1 technology and outlining future Earth science mission needs is the ability of the technology to characterize terrestrial surface state and processes. EO-1 is participating in a broad range of investigations, demonstrating the utility of imaging spectroscopy in applications relating to forestry, agriculture, species discrimination, invasive species, desertification, land-use, vulcanization, fire management, homeland security, natural and anthropogenic hazards and disaster assessments and has provided characterization for a variety of instruments on EOS platforms. By generating a high spectral and spatial resolution data set for the corral reefs and islands, it is contributing for realizing the goals of the National Decadal survey and providing an excellent platform for testing strategies to be employed in the HyspIRI mission. The EO1 Mission Science Office (MSO) is developing tools and prototypes for new science products, addressing the HyspIRI goals to assess vegetation status and health and provide vegetation spectral bio-indicators and biophysical parameters such as LAI and fAPAR at <100 m spatial resolution. These are being used to resolve variability in heterogeneous areas (e.g. agriculture, narrow shapes, urban and developed lands) and for managed ecosystems less than 10 km2. A set of invariable reference targets (e.g. sun, moon, deserts, Antarctica) are being characterised to allow cross-calibration of current and future EO sensors, comparison of land products generated by multiple sensors and retroactive processing of time series data. Such products are needed to develop Science Requirements for the next generation of hyperspectral satellite sensors and to address global societal needs.

  10. Technical Needs for Prototypic Prognostic Technique Demonstration for Advanced Small Modular Reactor Passive Components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meyer, Ryan M.; Coble, Jamie B.; Hirt, Evelyn H.

    2013-05-17

    This report identifies a number of requirements for prognostics health management of passive systems in AdvSMRs, documents technical gaps in establishing a prototypical prognostic methodology for this purpose, and describes a preliminary research plan for addressing these technical gaps. AdvSMRs span multiple concepts; therefore a technology- and design-neutral approach is taken, with the focus being on characteristics that are likely to be common to all or several AdvSMR concepts. An evaluation of available literature is used to identify proposed concepts for AdvSMRs along with likely operational characteristics. Available operating experience of advanced reactors is used in identifying passive components thatmore » may be subject to degradation, materials likely to be used for these components, and potential modes of degradation of these components. This information helps in assessing measurement needs for PHM systems, as well as defining functional requirements of PHM systems. An assessment of current state-of-the-art approaches to measurements, sensors and instrumentation, diagnostics and prognostics is also documented. This state-of-the-art evaluation, combined with the requirements, may be used to identify technical gaps and research needs in the development, evaluation, and deployment of PHM systems for AdvSMRs. A preliminary research plan to address high-priority research needs for the deployment of PHM systems to AdvSMRs is described, with the objective being the demonstration of prototypic prognostics technology for passive components in AdvSMRs. Greater efficiency in achieving this objective can be gained through judicious selection of materials and degradation modes that are relevant to proposed AdvSMR concepts, and for which significant knowledge already exists. These selections were made based on multiple constraints including the analysis performed in this document, ready access to laboratory-scale facilities for materials testing and measurement

  11. 46 CFR 68.5 - Requirements for citizenship under 46 U.S.C. App. 883-1.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Requirements for citizenship under 46 U.S.C. App. 883-1... Engaging in Limited Coastwise Trade § 68.5 Requirements for citizenship under 46 U.S.C. App. 883-1. A corporation seeking to establish its citizenship under the Act of September 2, 1958 (46 U.S.C. App. 883-1...

  12. 46 CFR 68.5 - Requirements for citizenship under 46 U.S.C. App. 883-1.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Requirements for citizenship under 46 U.S.C. App. 883-1... Engaging in Limited Coastwise Trade § 68.5 Requirements for citizenship under 46 U.S.C. App. 883-1. A corporation seeking to establish its citizenship under the Act of September 2, 1958 (46 U.S.C. App. 883-1...

  13. Integral Inherently Safe Light Water Reactor (I 2S-LWR)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Petrovic, Bojan; Memmott, Matthew; Boy, Guy

    This final report summarizes results of the multi-year effort performed during the period 2/2013- 12/2016 under the DOE NEUP IRP Project “Integral Inherently Safe Light Water Reactors (I 2S-LWR)”. The goal of the project was to develop a concept of a 1 GWe PWR with integral configuration and inherent safety features, at the same time accounting for lessons learned from the Fukushima accident, and keeping in mind the economic viability of the new concept. Essentially (see Figure 1-1) the project aimed to implement attractive safety features, typically found only in SMRs, to a larger power (1 GWe) reactor, to addressmore » the preference of some utilities in the US power market for unit power level on the order of 1 GWe.« less

  14. The U.S. Geological Survey's TRIGA® reactor

    USGS Publications Warehouse

    DeBey, Timothy M.; Roy, Brycen R.; Brady, Sally R.

    2012-01-01

    The U.S. Geological Survey (USGS) operates a low-enriched uranium-fueled, pool-type reactor located at the Federal Center in Denver, Colorado. The mission of the Geological Survey TRIGA® Reactor (GSTR) is to support USGS science by providing information on geologic, plant, and animal specimens to advance methods and techniques unique to nuclear reactors. The reactor facility is supported by programs across the USGS and is organizationally under the Associate Director for Energy and Minerals, and Environmental Health. The GSTR is the only facility in the United States capable of performing automated delayed neutron analyses for detecting fissile and fissionable isotopes. Samples from around the world are submitted to the USGS for analysis using the reactor facility. Qualitative and quantitative elemental analyses, spatial elemental analyses, and geochronology are performed. Few research reactor facilities in the United States are equipped to handle the large number of samples processed at the GSTR. Historically, more than 450,000 sample irradiations have been performed at the USGS facility. Providing impartial scientific information to resource managers, planners, and other interested parties throughout the world is an integral part of the research effort of the USGS.

  15. 97. ARAIII. ML1 reactor has been moved into GCRE reactor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    97. ARA-III. ML-1 reactor has been moved into GCRE reactor building (ARA-608) for examination of corrosion on its underside and repair. May 24, 1963. Ineel photo no. 63-3485. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  16. Calculation of the Ti(C y N1- y )-Ti4C2S2-MnS-austenite equilibrium in Ti-bearing steels

    NASA Astrophysics Data System (ADS)

    Liu, W. J.; Jonas, J. J.

    1989-08-01

    A thermodynamic model is presented for the equilibria among various precipitates (Ti(C y N1- y ), Ti4C2S2, and MnS) and austenite containing six alloying elements (C, Mn, N, S, Si, and Ti). This model is applied to four microalloyed steels with Ti levels of 0.05, 0.11, 0.18, and 0.25 pct. The calculations show that the Ti in these steels cannot be completely dissolved over the austenite temperature range. However, the compositions of the undissolved Ti carbonitrides differ significantly from pure TiN, as 10 to 40 pct of the nitrogen is replaced by carbon. An expression for the Gibbs energy for the formation of Ti4C2S2 in austenite is estimated. The present predictions are compared with those of the Hudd, Jones, and Kale (HJK) model; considerable differences are observed at temperatures below 1250°C.

  17. PT-IP-759, channel caulking tests: C Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cooke, J.P.; Russell, A.

    1965-03-19

    The graphite movement which has occurred at the various reactors has been characterized by two problems: (1) Crooked channels and (2) cracks and miscellaneous voids where pieces of blocks are missing. Of these problems, the cracks and voids have been the most serious in the case of ball drops. Alleviation of the crooked channels can sometimes be accomplished by graphite removal methods such as broaching, but unless some method is found to prevent the balls from entering cracks, the total effect of a ball drop would still be intolerable. Of the two methods of closing the cracks, a paste caulkingmore » procedure is anticipated to be less expensive than sleeving, both in terms of cost of the operation and the number of process tube channels which might be lost. If the VSR channel does not require drastic straightening or entry of large tooling, satisfactory caulking can be done without removal of the step plug. ``Poison`` chain may be considered as an alternative to caulking or sleeving for those outer VSR channels where the sole use of balls is for ``total control`` rather than ``speed of control.`` The objectives of this test are (1) to authorize the experimental crack filling of one or two of the VSR channels at C Reactor with a wet mixture of graphite and sugar, (2) to demonstrate the durability of this mixture in subsequent normal reactor operation, and (3) to demonstrate by testing (actual or simulated ball drops) and borescoping, that the channels are or are not again acceptable for use with the normal charge of balls.« less

  18. 42. ARAIII Prototype assembly and evaluation building ARA630 interior. Typical ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    42. ARA-III Prototype assembly and evaluation building ARA-630 interior. Typical view room partitions. Ineel photo no. 3-28. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  19. JEN-1 Reactor Control System; SISTEMA DE CONTROL DEL REACTOR JEN-1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cantillo, M.F.; Nuno, C.M.; Andreu, J.L.M.

    1963-01-01

    ABS>The JEN-1 3Mw power swimming pool reactor electrical control circuits are described. Start-up, power generation in the core, and shutdown are controlled by the reactor control system. This control system guarantees in each moment the safety conditions during reactor operation. Each circuit was represented by a scheme, complemented with a description of its function, components, and operation theory. Components described include: scram circuit; fission counter control circuit; servo control circuit; control circuit of safety sheets; control circuits of primary, secondary, and clean-up pump motors and tower fan motor; primary valve motor circuit; center cubicle alarm circuit; and process alarm circuit.more » (auth)« less

  20. A PC-based high temperature gas reactor simulator for Indonesian conceptual HTR reactor basic training

    NASA Astrophysics Data System (ADS)

    Syarip; Po, L. C. C.

    2018-05-01

    In planning for nuclear power plant construction in Indonesia, helium cooled high temperature reactor (HTR) is favorable for not relying upon water supply that might be interrupted by earthquake. In order to train its personnel, BATAN has cooperated with Micro-Simulation Technology of USA to develop a 200 MWt PC-based simulation model PCTRAN/HTR. It operates in Win10 environment with graphic user interface (GUI). Normal operation of startup, power maneuvering, shutdown and accidents including pipe breaks and complete loss of AC power have been conducted. A sample case of safety analysis simulation to demonstrate the inherent safety features of HTR was done for helium pipe break malfunction scenario. The analysis was done for the variation of primary coolant pipe break i.e. from 0,1% - 0,5 % and 1% - 10 % helium gas leakages, while the reactor was operated at the maximum constant power of 10 MWt. The result shows that the highest temperature of HTR fuel centerline and coolant were 1150 °C and 1296 °C respectively. With 10 kg/s of helium flow in the reactor core, the thermal power will back to the startup position after 1287 s of helium pipe break malfunction.

  1. C-H···O Hydrogen Bonding. The Prototypical Methane-Formaldehyde System: A Critical Assessment.

    PubMed

    Moore, Kevin B; Sadeghian, Keyarash; Sherrill, C David; Ochsenfeld, Christian; Schaefer, Henry F

    2017-11-14

    Distinguishing the functionality of C-H···O hydrogen bonds (HBs) remains challenging, because their properties are difficult to quantify reliably. Herein, we present a study of the model methane-formaldehyde complex (MFC). Six stationary points on the MFC potential energy surface (PES) were obtained at the CCSD(T)/ANO2 level. The CCSDT(Q)/CBS interaction energies of the conformers range from only -1.12 kcal mol -1 to -0.33 kcal mol -1 , denoting a very flat PES. Notably, only the lowest energy stationary point (MFC1) corresponds to a genuine minimum, whereas all other stationary points-including the previously studied ideal case of a e (C-H···O) = 180°-exhibit some degree of freedom that leads to MFC1. Despite the flat PES, we clearly see that the HB properties of MFC1 align with those of the prototypical water dimer O-H···O HB. Each HB property generally becomes less prominent in the higher-energy conformers. Only the MFC1 conformer prominently exhibits (1) elongated C-H donor bonds, (2) attractive C-H···O═C interactions, (3) n(O) → σ*(C-H) hyperconjugation, (4) critical points in the electron density from Bader's method and from the noncovalent interactions method, (5) positively charged donor hydrogen, and (6) downfield NMR chemical shifts and nonzero 2 J(C M -H M ···O F ) coupling constants. Based on this research, some issues merit further study. The flat PES hinders reliable determinations of the HB-induced shifts of the C-H stretches; a similarly difficult challenge is observed for the experiment. The role of charge transfer in HBs remains an intriguing open question, although our BLW and NBO computations suggest that it is relevant to the C-H···O HB geometries. These issues notwithstanding, the prominence of the HB properties in MFC1 serves as clear evidence that the MFC is predominantly bound by a C-H···O HB.

  2. ON THE ABSENCE OF EUV EMISSION FROM COMET C/2012 S1 (ISON)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bryans, Paul; Pesnell, W. Dean

    2016-05-10

    When the sungrazing comet C/2012 S1 (ISON) made its perihelion passage within two solar radii of the Sun’s surface, it was expected to be a bright emitter at extreme ultraviolet (EUV) wavelengths. However, despite solar EUV telescopes repointing to track the orbit of the comet, no emission was detected. This “null result” is interesting in its own right, offering the possibility of placing limits on the size and composition of the nucleus. We explain the lack of detection by considering the properties of the comet and the solar atmosphere that determine the intensity of EUV emission from sungrazing comets. Bymore » comparing these properties with those of sungrazing comet C/2011 W3 (Lovejoy), which did emit in the EUV, we conclude that the primary factor resulting in non-detectable EUV emission from C/2012 S1 (ISON) was an insufficiently large nucleus. We conclude that the radius of C/2012 S1 (ISON) was at least a factor of four less than that of C/2011 W3 (Lovejoy). This is consistent with white-light observations in the days before perihelion that suggested the comet was dramatically reducing in size on approach.« less

  3. Integration of the Execution Support System for the Computer-Aided Prototyping System (CAPS)

    DTIC Science & Technology

    1990-09-01

    SUPPORT SYSTEM FOR THE COMPUTER -AIDED PROTOTYPING SYSTEM (CAPS) by Frank V. Palazzo September 1990 Thesis Advisor: Luq± Approved for public release...ZATON REPOR ,,.VBE (, 6a NAME OF PERPORMING ORGAN ZAT7ON 6b OFF:CE SYVBOL 7a NAME OF MONITORINC O0-CA’Za- ON Computer Science Department (if applicable...Include Security Classification) Integration of the Execution Support System for the Computer -Aided Prototyping System (C S) 12 PERSONAL AUTHOR(S) Frank V

  4. An atmospheric pressure flow reactor: Gas phase kinetics and mechanism in tropospheric conditions without wall effects

    NASA Technical Reports Server (NTRS)

    Koontz, Steven L.; Davis, Dennis D.; Hansen, Merrill

    1988-01-01

    A new type of gas phase flow reactor, designed to permit the study of gas phase reactions near 1 atm of pressure, is described. A general solution to the flow/diffusion/reaction equations describing reactor performance under pseudo-first-order kinetic conditions is presented along with a discussion of critical reactor parameters and reactor limitations. The results of numerical simulations of the reactions of ozone with monomethylhydrazine and hydrazine are discussed, and performance data from a prototype flow reactor are presented.

  5. Use of statecharts in the modelling of dynamic behaviour in the ATLAS DAQ prototype-1

    NASA Astrophysics Data System (ADS)

    Croll, P.; Duval, P.-Y.; Jones, R.; Kolos, S.; Sari, R. F.; Wheeler, S.

    1998-08-01

    Many applications within the ATLAS DAQ prototype-1 system have complicated dynamic behaviour which can be successfully modelled in terms of states and transitions between states. Previously, state diagrams implemented as finite-state machines have been used. Although effective, they become ungainly as system size increases. Harel statecharts address this problem by implementing additional features such as hierarchy and concurrency. The CHSM object-oriented language system is freeware which implements Harel statecharts as concurrent, hierarchical, finite-state machines (CHSMs). An evaluation of this language system by the ATLAS DAQ group has shown it to be suitable for describing the dynamic behaviour of typical DAQ applications. The language is currently being used to model the dynamic behaviour of the prototype-1 run-control system. The design is specified by means of a CHSM description file, and C++ code is obtained by running the CHSM compiler on the file. In parallel with the modelling work, a code generator has been developed which translates statecharts, drawn using the StP CASE tool, into the CHSM language. C++ code, describing the dynamic behaviour of the run-control system, has been successfully generated directly from StP statecharts using the CHSM generator and compiler. The validity of the design was tested using the simulation features of the Statemate CASE tool.

  6. 40. ARAIII Prototype assembly and evaluation building ARA630. East end ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    40. ARA-III Prototype assembly and evaluation building ARA-630. East end and south side of building. Camera facing west. Roof railing is part of demolition preparations. Building beyond ARA-622 is ARA-621. In left of view is reactor building. ARA-607 is low-roofed portion, while high-bay portion is ARA-608. Ineel photo no. 3-27. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  7. On the Absence of EUV Emission from Comet C/2012 S1 (ISON)

    NASA Technical Reports Server (NTRS)

    Bryans, Paul; Pesnell, W. Dean

    2016-01-01

    When the sungrazing comet C2012 S1 (ISON) made its perihelion passage within two solar radii of the Sun's surface, it was expected to be a bright emitter at extreme ultraviolet (EUV) wavelengths. However, despite solar EUV telescopes repointing to track the orbit of the comet, no emission was detected. This null result is interesting in its own right, offering the possibility of placing limits on the size and composition of the nucleus. We explain the lack of detection by considering the properties of the comet and the solar atmosphere that determine the intensity of EUV emission from sungrazing comets. By comparing these properties with those of sungrazing comet C2011 W3 (Lovejoy), which did emit in the EUV, we conclude that the primary factor resulting in non-detectable EUV emission from C2012 S1 (ISON) was an insufficiently large nucleus. We conclude that the radius of C2012 S1 (ISON) was at least a factor of four less than that of C2011 W3 (Lovejoy). This is consistent with white-light observations in the days before perihelion that suggested the comet was dramatically reducing in size on approach.

  8. Assessment of Sensor Technologies for Advanced Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Korsah, Kofi; Kisner, R. A.; Britton Jr., C. L.

    This paper provides an assessment of sensor technologies and a determination of measurement needs for advanced reactors (AdvRx). It is a summary of a study performed to provide the technical basis for identifying and prioritizing research targets within the instrumentation and control (I&C) Technology Area under the Department of Energy’s (DOE’s) Advanced Reactor Technology (ART) program. The study covered two broad reactor technology categories: High Temperature Reactors and Fast Reactors. The scope of “High temperature reactors” included Gen IV reactors whose coolant exit temperatures exceed ≈650 °C and are moderated (as opposed to fast reactors). To bound the scope formore » fast reactors, this report reviewed relevant operating experience from US-operated Sodium Fast Reactor (SFR) and relevant test experience from the Fast Flux Test Facility (FFTF). For high temperature reactors the study showed that in many cases instrumentation have performed reasonably well in research and demonstration reactors. However, even in cases where the technology is “mature” (such as thermocouples), HTGRs can benefit from improved technologies. Current HTGR instrumentation is generally based on decades-old technology and adapting newer technologies could provide significant advantages. For sodium fast reactors, the study found that several key research needs arise around (1) radiation-tolerant sensor design for in-vessel or in-core applications, where possible non-invasive sensing approaches for key parameters that minimize the need to deploy sensors in-vessel, (2) approaches to exfiltrating data from in-vessel sensors while minimizing penetrations, (3) calibration of sensors in-situ, and (4) optimizing sensor placements to maximize the information content while minimizing the number of sensors needed.« less

  9. SL-1 Accident Briefing Report - 1961 Nuclear Reactor Meltdown Educational Documentary

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2013-09-25

    U.S. Atomic Energy Commission (Idaho Operations Office) briefing about the SL-1 Nuclear Reactor Meltdown. The SL-1, or Stationary Low-Power Reactor Number One, was a United States Army experimental nuclear power reactor which underwent a steam explosion and meltdown on January 3, 1961, killing its three operators. The direct cause was the improper withdrawal of the central control rod, responsible for absorbing neutrons in the reactor core. The event is the only known fatal reactor accident in the United States. The accident released about 80 curies (3.0 TBq) of Iodine-131, which was not considered significant due to its location in amore » remote desert of Idaho. About 1,100 curies (41 TBq) of fission products were released into the atmosphere. The facility, located at the National Reactor Testing Station approximately 40 miles (64 km) west of Idaho Falls, Idaho, was part of the Army Nuclear Power Program and was known as the Argonne Low Power Reactor (ALPR) during its design and build phase. It was intended to provide electrical power and heat for small, remote military facilities, such as radar sites near the Arctic Circle, and those in the DEW Line. The design power was 3 MW (thermal). Operating power was 200 kW electrical and 400 kW thermal for space heating. In the accident, the core power level reached nearly 20 GW in just four milliseconds, precipitating the reactor accident and steam explosion.« less

  10. SL-1 Accident Briefing Report - 1961 Nuclear Reactor Meltdown Educational Documentary

    ScienceCinema

    None

    2018-01-16

    U.S. Atomic Energy Commission (Idaho Operations Office) briefing about the SL-1 Nuclear Reactor Meltdown. The SL-1, or Stationary Low-Power Reactor Number One, was a United States Army experimental nuclear power reactor which underwent a steam explosion and meltdown on January 3, 1961, killing its three operators. The direct cause was the improper withdrawal of the central control rod, responsible for absorbing neutrons in the reactor core. The event is the only known fatal reactor accident in the United States. The accident released about 80 curies (3.0 TBq) of Iodine-131, which was not considered significant due to its location in a remote desert of Idaho. About 1,100 curies (41 TBq) of fission products were released into the atmosphere. The facility, located at the National Reactor Testing Station approximately 40 miles (64 km) west of Idaho Falls, Idaho, was part of the Army Nuclear Power Program and was known as the Argonne Low Power Reactor (ALPR) during its design and build phase. It was intended to provide electrical power and heat for small, remote military facilities, such as radar sites near the Arctic Circle, and those in the DEW Line. The design power was 3 MW (thermal). Operating power was 200 kW electrical and 400 kW thermal for space heating. In the accident, the core power level reached nearly 20 GW in just four milliseconds, precipitating the reactor accident and steam explosion.

  11. Development and Prototyping of the PROSPECT Antineutrino Detector

    NASA Astrophysics Data System (ADS)

    Commeford, Kelley; Prospect Collaboration

    2017-01-01

    The PROSPECT experiment will make the most precise measurement of the 235U reactor antineutrino spectrum as well as search for sterile neutrinos using a segmented Li-loaded liquid scintillator neutrino detector. Several prototype detectors of increasing size, complexity, and fidelity have been constructed and tested as part of the PROSPECT detector development program. The challenges to overcome include the efficient rejection of cosmogenic background and collection of optical photons in a compact volume. Design choices regarding segment structure and layout, calibration source deployment, and optical collection methods are discussed. Results from the most recent multi-segment prototype, PROSPECT-50, will also be shown.

  12. (Carbonyl-1κC)bis-[2,3(η)-cyclo-penta-dien-yl][μ(3)-(S-methyl trithio-carbonato)methylidyne-1:2:3κC,S'':C:C](triphenyl-phosphine-1κP)(μ(3)-sulfido-1:2:3κS)dicobalt(II)iron(II) trifluoro-methane-sulfonate.

    PubMed

    Manning, Anthony R; McAdam, C John; Palmer, Anthony J; Simpson, Jim

    2008-04-10

    The asymmetric unit of the title compound, [FeCo(2)(C(5)H(5))(2)(C(3)H(3)S(3))S(C(18)H(15)P)(CO)]CF(3)SO(3), consists of a triangular irondicobalt cluster cation and a trifluoro-methane-sulfonate anion. In the cation, the FeCo(2) triangle is symmetrically capped on one face by an S atom and on the other by a C atom linked to a methyl trithio-carbonate residue that bridges the Fe-C bond. Each Co atom carries a cyclo-penta-dienyl ligand while the Fe atom coordinates to one carbonyl and one triphenyl-phosphine ligand. In the crystal structure, the cation is linked to the anion by a number of weak non-classical C-H⋯O and C-H⋯F hydrogen bonds and weak S⋯O (3.317 Å) and S⋯F (3.198 Å) inter-actions. The structure is further stabilized by additional inter-molecular C-H⋯O, C-H⋯F and O⋯O (2.942 Å) contacts, together with an unusual S⋯π(Cp) inter-action (S⋯centroid distance = 3.385 Å), generating an extended network.

  13. 41. ARAIII Prototype assembly and evaluation building ARA630. West end ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    41. ARA-III Prototype assembly and evaluation building ARA-630. West end and south side of building. Camera facing northeast. Ineel photo no. 3-22. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  14. Hydrogeological Analysis and Groundwater Flow for C-Reactor Area with Contaminant Transport for C-Reactor Seepage Basins (CRSB) and C-Area Burning/Rubble Pit (CBRP)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    FLACH, GREGORYP.

    1999-12-01

    A groundwater flow model encompassing approximately 4 mi2 within C Reactor area has been developed. The objectives and goals of the C Reactor Area groundwater model are to: Provide a common hydrogeologic and groundwater flow modeling framework for C Area that can be easily updated as additional field data is collected from waste site investigations. Provide a baseline groundwater flow model for use in subsequent flow and transport simulations for remedial/feasibility studies for C Area waste sites. Provide baseline transport simulations for CBRP and CRSB that reconstruct historical contaminant distributions and simulate future plume migration from each waste unit. Providemore » a working groundwater flow model for particle tracking and analysis to guide subsequent field characterization activities. The model incorporates historical and current field characterization data up through spring 1999. The model simulates groundwater flow within the area bounded to the west and north by Fourmile Branch, to the south by Caster Creek, and to the east by a line between Fourmile Branch and the headwaters of Caster Creek. Vertically the model extends from ground surface to the top of the Gordon aquifer. The chosen areal grid is 14,600 by 13,200 feet with a resolution of 200 feet. The model accurately reproduces groundwater flow directions from the CBRP and CRSB, and matches targets for hydraulic head, recharge and baseflow within calibration goals. The hydrogeologic model reflects aquifer heterogeneity as derived from CPT lithologic data.« less

  15. Saturn V First Stage (S-1C) At MSFC

    NASA Technical Reports Server (NTRS)

    1960-01-01

    This small group of unidentified officials is dwarfed by the gigantic size of the Saturn V first stage (S-1C) at the shipping area of the Manufacturing Engineering Laboratory at Marshall Space Flight Center in Huntsville, Alabama. The towering 363-foot Saturn V was a multi-stage, multi-engine launch vehicle standing taller than the Statue of Liberty. Altogether, the Saturn V engines produced as much power as 85 Hoover Dams.

  16. Implementation of a quantum cascade laser-based gas sensor prototype for sub-ppmv H2S measurements in a petrochemical process gas stream.

    PubMed

    Moser, Harald; Pölz, Walter; Waclawek, Johannes Paul; Ofner, Johannes; Lendl, Bernhard

    2017-01-01

    The implementation of a sensitive and selective as well as industrial fit gas sensor prototype based on wavelength modulation spectroscopy with second harmonic detection (2f-WMS) employing an 8-μm continuous-wave distributed feedback quantum cascade laser (CW-DFB-QCL) for monitoring hydrogen sulfide (H 2 S) at sub-ppm levels is reported. Regarding the applicability for analytical and industrial process purposes aimed at petrochemical environments, a synthetic methane (CH 4 ) matrix of up to 1000 ppmv together with a varying H 2 S content was chosen as the model environment for the laboratory-based performance evaluation performed at TU Wien. A noise-equivalent absorption sensitivity (NEAS) for H 2 S targeting the absorption line at 1247.2 cm -1 was found to be 8.419 × 10 -10  cm -1  Hz -1/2 , and a limit of detection (LOD) of 150 ppbv H 2 S could be achieved. The sensor prototype was then deployed for on-site measurements at the petrochemical research hydrogenation platform of the industrial partner OMV AG. In order to meet the company's on-site safety regulations, the H 2 S sensor platform was installed in an industry rack and equipped with the required safety infrastructure for protected operation in hazardous and explosive environments. The work reports the suitability of the sensor prototype for simultaneous monitoring of H 2 S and CH 4 content in the process streams of a research hydrodesulfurization (HDS) unit. Concentration readings were obtained every 15 s and revealed process dynamics not observed previously.

  17. [Hepatitis C virus: sequence homology of a European isolate and divergence from the prototype].

    PubMed

    Seelig, R; Seelig, H P; Renz, M

    1991-08-01

    The polymerase chain reaction (PCR) detected specific hepatitis C viral (HCV) RNA sequences in liver biopsies from two patients with chronic hepatitis, in the tissue of a liver implantate, in plasma from four chronic non-A, non-B hepatitis (NANBH) patients and, for the first time, in an infectious anti-D-immunoglobulin preparation. A comparison of the viral sequences coding for a region for the nonstructural NS3 protein from the liver tissues revealed only a very small degree of sequence divergence on the cDNA as well as on the amino acid level (between 0 and 5%). The sequence similarities of the RNA isolated from plasma of the four chronic NANBH patients and the anti-D-immunoglobulin preparation were partly somewhat lower but altogether also high (between 90 and 100%). In contrast, all eight cDNA and amino acid sequences exhibited a significantly higher degree of divergence in comparison with the HCV prototype sequence (between 29 and 32%) than among themselves (between 0 and 10%). This unexpected high sequence similarity of the eight European isolates and their low homology to the Northamerican prototype sequence is indicative for the existence of different types of HCV. This will be important not only for epidemiological studies but also for the development of effective diagnostic procedures and vaccines. Concerning the pathogenesis of NANBH, a double infection or a helper mechanism has to be considered: in addition to the C virus, sequences of an other virus particle were found in the infectious IgG preparation as well as in the liver biopsies.

  18. 11 CFR 105.1 - Place of filing; House candidates and their authorized committees (2 U.S.C. 432(g)(1)).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Place of filing; House candidates and their authorized committees (2 U.S.C. 432(g)(1)). 105.1 Section 105.1 Federal Elections FEDERAL ELECTION COMMISSION GENERAL DOCUMENT FILING (2 U.S.C. 432(g)) § 105.1 Place of filing; House candidates and their authorized...

  19. 11 CFR 105.1 - Place of filing; House candidates and their authorized committees (2 U.S.C. 432(g)(1)).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 11 Federal Elections 1 2011-01-01 2011-01-01 false Place of filing; House candidates and their authorized committees (2 U.S.C. 432(g)(1)). 105.1 Section 105.1 Federal Elections FEDERAL ELECTION COMMISSION GENERAL DOCUMENT FILING (2 U.S.C. 432(g)) § 105.1 Place of filing; House candidates and their authorized...

  20. SmoXYB1C1Z of Mycobacterium sp. Strain NBB4: a Soluble Methane Monooxygenase (sMMO)-Like Enzyme, Active on C2 to C4 Alkanes and Alkenes

    PubMed Central

    Martin, Kiri E.; Ozsvar, Jazmin

    2014-01-01

    Monooxygenase (MO) enzymes initiate the aerobic oxidation of alkanes and alkenes in bacteria. A cluster of MO genes (smoXYB1C1Z) of thus-far-unknown function was found previously in the genomes of two Mycobacterium strains (NBB3 and NBB4) which grow on hydrocarbons. The predicted Smo enzymes have only moderate amino acid identity (30 to 60%) to their closest homologs, the soluble methane and butane MOs (sMMO and sBMO), and the smo gene cluster has a different organization from those of sMMO and sBMO. The smoXYB1C1Z genes of NBB4 were cloned into pMycoFos to make pSmo, which was transformed into Mycobacterium smegmatis mc2-155. Cells of mc2-155(pSmo) metabolized C2 to C4 alkanes, alkenes, and chlorinated hydrocarbons. The activities of mc2-155(pSmo) cells were 0.94, 0.57, 0.12, and 0.04 nmol/min/mg of protein with ethene, ethane, propane, and butane as substrates, respectively. The mc2-155(pSmo) cells made epoxides from ethene, propene, and 1-butene, confirming that Smo was an oxygenase. Epoxides were not produced from larger alkenes (1-octene and styrene). Vinyl chloride and 1,2-dichloroethane were biodegraded by cells expressing Smo, with production of inorganic chloride. This study shows that Smo is a functional oxygenase which is active against small hydrocarbons. M. smegmatis mc2-155(pSmo) provides a new model for studying sMMO-like monooxygenases. PMID:25015887

  1. Characterizing the biotransformation of sulfur-containing wastes in simulated landfill reactors.

    PubMed

    Sun, Wenjie; Sun, Mei; Barlaz, Morton A

    2016-07-01

    Landfills that accept municipal solid waste (MSW) in the U.S. may also accept a number of sulfur-containing wastes including residues from coal or MSW combustion, and construction and demolition (C&D) waste. Under anaerobic conditions that dominate landfills, microbially mediated processes can convert sulfate to hydrogen sulfide (H2S). The presence of H2S in landfill gas is problematic for several reasons including its low odor threshold, human toxicity, and corrosive nature. The objective of this study was to develop and demonstrate a laboratory-scale reactor method to measure the H2S production potential of a range of sulfur-containing wastes. The H2S production potential was measured in 8-L reactors that were filled with a mixture of the target waste, newsprint as a source of organic carbon required for microbial sulfate reduction, and leachate from decomposed residential MSW as an inoculum. Reactors were operated with and without N2 sparging through the reactors, which was designed to reduce H2S accumulation and toxicity. Both H2S and CH4 yields were consistently higher in reactors that were sparged with N2 although the magnitude of the effect varied. The laboratory-measured first order decay rate constants for H2S and CH4 production were used to estimate constants that were applicable in landfills. The estimated constants ranged from 0.11yr(-1) for C&D fines to 0.38yr(-1) for a mixed fly ash and bottom ash from MSW combustion. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. 33 CFR 110.72c - Lake Murray, S.C.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Lake Murray, S.C. 110.72c Section 110.72c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.72c Lake Murray, S.C. (a) The area beginning at the 125...

  3. 33 CFR 110.72c - Lake Murray, S.C.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Lake Murray, S.C. 110.72c Section 110.72c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.72c Lake Murray, S.C. (a) The area beginning at the 125...

  4. 33 CFR 110.72c - Lake Murray, S.C.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Lake Murray, S.C. 110.72c Section 110.72c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.72c Lake Murray, S.C. (a) The area beginning at the 125...

  5. 33 CFR 110.72c - Lake Murray, S.C.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Lake Murray, S.C. 110.72c Section 110.72c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.72c Lake Murray, S.C. (a) The area beginning at the 125...

  6. 33 CFR 110.72c - Lake Murray, S.C.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Lake Murray, S.C. 110.72c Section 110.72c Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.72c Lake Murray, S.C. (a) The area beginning at the 125...

  7. Functional Design for Air Intercept Controller Prototype Training System.

    DTIC Science & Technology

    1981-12-01

    DEC 81 E REGELSON. 0 SLENON, R VERSTEE6 N61339-?-C-OIG* UNCLASSIFIED G61I-A009 NAVTRAEUIPC-70-C-0182-B 14. . !EEEEEEEEEEElIEEIIIEEIIEEI IEIIEIIIEIIII...INTERCEPT CON4TROLLER PROTOTYPE TRAINING SYSTEK E . Regelson, G. Slemon, R. VerSteeg, R. Halley Logicon, Inc. Tactical & Training Systems Division Post...Final epr 7. AUTWOaN( L CONTRACT OR GONI’?MUMBILN(s) E . Regelson, G. Slemon, R. VerSteeg, R. Halley N61339-78-C-0182 9. P6141ORMING ORGANIZATION

  8. Nuclear design of a vapor core reactor for space nuclear propulsion

    NASA Astrophysics Data System (ADS)

    Dugan, Edward T.; Watanabe, Yoichi; Kuras, Stephen A.; Maya, Isaac; Diaz, Nils J.

    1993-01-01

    Neutronic analysis methodology and results are presented for the nuclear design of a vapor core reactor for space nuclear propulsion. The Nuclear Vapor Thermal Reactor (NVTR) Rocket Engine uses modified NERVA geometry and systems which the solid fuel replaced by uranium tetrafluoride vapor. The NVTR is an intermediate term gas core thermal rocket engine with specific impulse in the range of 1000-1200 seconds; a thrust of 75,000 lbs for a hydrogen flow rate of 30 kg/s; average core exit temperatures of 3100 K to 3400 K; and reactor thermal powers of 1400 to 1800 MW. Initial calculations were performed on epithermal NVTRs using ZrC fuel elements. Studies are now directed at thermal NVTRs that use fuel elements made of C-C composite. The large ZrC-moderated reactors resulted in thrust-to-weight ratios of only 1 to 2; the compact C-C composite systems yield thrust-to-weight ratios of 3 to 5.

  9. Lifetime Neutron Fluence Analysis of the Ringhals Unit 1 Boiling Water Reactor

    NASA Astrophysics Data System (ADS)

    Kulesza, Joel A.; Roudén, Jenny; Green, Eva-Lena

    2016-02-01

    This paper describes a neutron fluence assessment considering the entire commercial operating history (35 cycles or ˜ 25 effective full power years) of the Ringhals Unit 1 reactor pressure vessel beltline region. In this assessment, neutron (E >1.0 MeV) fluence and iron atom displacement distributions were calculated on the moderator tank and reactor pressure vessel structures. To validate those calculations, five in-vessel surveillance chain dosimetry sets were evaluated as well as material samples taken from the upper core grid and wide range neutron monitor tubes to act as a form of retrospective dosimetry. During the analysis, it was recognized that delays in characterizing the retrospective dosimetry samples reduced the amount of reactions available to be counted and complicated the material composition determination. However, the comparisons between the surveillance chain dosimetry measurements (M) and calculated (C) results show similar and consistent results with the linear average M/C ratio of 1.13 which is in good agreement with the resultant least squares best estimate (BE)/C ratios of 1.10 for both neutron (E >1.0 MeV) flux and iron atom displacement rate.

  10. Synthesis of 1,2,4-Triazoles via Oxidative Heterocyclization: Selective C-N Bond Over C-S Bond Formation.

    PubMed

    Gogoi, Anupal; Guin, Srimanta; Rajamanickam, Suresh; Rout, Saroj Kumar; Patel, Bhisma K

    2015-09-18

    The higher propensity of C-N over C-S bond forming ability was demonstrated, through formal C-H functionalization during the construction of 4,5-disubstituted 1,2,4-triazole-3-thiones from arylidenearylthiosemicarbazides catalyzed by Cu(II). However, steric factors imparted by the o-disubstituted substrates tend to change the reaction path giving thiodiazole as the major or an exclusive product. Upon prolonging the reaction time, the in situ generated thiones are transformed to 4,5-disubstituted 1,2,4-triazoles via a desulfurization process. Two classes of heterocycles viz. 4,5-disubstituted 1,2,4-triazole-3-thiones and 4,5-disubstituted 1,2,4-triazoles can be synthesized from arylidenearylthiosemicarbazides by simply adjusting the reaction time. Desulfurization of 1,2,4-triazole-3-thiones is assisted by thiophilic Cu to provide 1,2,4-triazoles with concomitant formation of CuS and polynuclear sulfur anions as confirmed from scanning electron microscope and energy dispersive X-ray spectroscopy measurements. A one-pot synthesis of an antimicrobial compound has been successfully achieved following this strategy.

  11. 10 CFR 1.44 - Office of New Reactors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Office of New Reactors. 1.44 Section 1.44 Energy NUCLEAR... Office of New Reactors. The Office of New Reactors— (a) Develops, promulgates and implements regulations... safeguarding of nuclear reactor facilities licensed under part 52 of this chapter prior to initial commencement...

  12. 10 CFR 1.44 - Office of New Reactors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Office of New Reactors. 1.44 Section 1.44 Energy NUCLEAR... Office of New Reactors. The Office of New Reactors— (a) Develops, promulgates and implements regulations... safeguarding of nuclear reactor facilities licensed under part 52 of this chapter prior to initial commencement...

  13. 10 CFR 1.44 - Office of New Reactors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Office of New Reactors. 1.44 Section 1.44 Energy NUCLEAR... safeguarding of nuclear reactor facilities licensed under part 52 of this chapter prior to initial commencement... Office of New Reactors. The Office of New Reactors— (a) Develops, promulgates and implements regulations...

  14. 10 CFR 1.44 - Office of New Reactors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Office of New Reactors. 1.44 Section 1.44 Energy NUCLEAR... safeguarding of nuclear reactor facilities licensed under part 52 of this chapter prior to initial commencement... Office of New Reactors. The Office of New Reactors— (a) Develops, promulgates and implements regulations...

  15. 10 CFR 1.44 - Office of New Reactors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Office of New Reactors. 1.44 Section 1.44 Energy NUCLEAR... safeguarding of nuclear reactor facilities licensed under part 52 of this chapter prior to initial commencement... Office of New Reactors. The Office of New Reactors— (a) Develops, promulgates and implements regulations...

  16. 47 CFR 1.736 - Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B). (a) Where a complaint is filed pursuant to 47 U.S.C. 271... deadline contained in 47 U.S.C. 271(d)(6)(B) in the following manner: (1) The complainant shall so indicate... filed pursuant to 47 U.S.C. 271(d)(6)(B) will not be entertained by the Commission staff subsequent to...

  17. 47 CFR 1.736 - Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B). (a) Where a complaint is filed pursuant to 47 U.S.C. 271... deadline contained in 47 U.S.C. 271(d)(6)(B) in the following manner: (1) The complainant shall so indicate... filed pursuant to 47 U.S.C. 271(d)(6)(B) will not be entertained by the Commission staff subsequent to...

  18. 47 CFR 1.736 - Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B). (a) Where a complaint is filed pursuant to 47 U.S.C. 271... deadline contained in 47 U.S.C. 271(d)(6)(B) in the following manner: (1) The complainant shall so indicate... filed pursuant to 47 U.S.C. 271(d)(6)(B) will not be entertained by the Commission staff subsequent to...

  19. 47 CFR 1.736 - Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B). (a) Where a complaint is filed pursuant to 47 U.S.C. 271... deadline contained in 47 U.S.C. 271(d)(6)(B) in the following manner: (1) The complainant shall so indicate... filed pursuant to 47 U.S.C. 271(d)(6)(B) will not be entertained by the Commission staff subsequent to...

  20. 47 CFR 1.736 - Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Complaints filed pursuant to 47 U.S.C. 271(d)(6)(B). (a) Where a complaint is filed pursuant to 47 U.S.C. 271... deadline contained in 47 U.S.C. 271(d)(6)(B) in the following manner: (1) The complainant shall so indicate... filed pursuant to 47 U.S.C. 271(d)(6)(B) will not be entertained by the Commission staff subsequent to...

  1. Software Prototyping

    PubMed Central

    Del Fiol, Guilherme; Hanseler, Haley; Crouch, Barbara Insley; Cummins, Mollie R.

    2016-01-01

    Summary Background Health information exchange (HIE) between Poison Control Centers (PCCs) and Emergency Departments (EDs) could improve care of poisoned patients. However, PCC information systems are not designed to facilitate HIE with EDs; therefore, we are developing specialized software to support HIE within the normal workflow of the PCC using user-centered design and rapid prototyping. Objective To describe the design of an HIE dashboard and the refinement of user requirements through rapid prototyping. Methods Using previously elicited user requirements, we designed low-fidelity sketches of designs on paper with iterative refinement. Next, we designed an interactive high-fidelity prototype and conducted scenario-based usability tests with end users. Users were asked to think aloud while accomplishing tasks related to a case vignette. After testing, the users provided feedback and evaluated the prototype using the System Usability Scale (SUS). Results Survey results from three users provided useful feedback that was then incorporated into the design. After achieving a stable design, we used the prototype itself as the specification for development of the actual software. Benefits of prototyping included having 1) subject-matter experts heavily involved with the design; 2) flexibility to make rapid changes, 3) the ability to minimize software development efforts early in the design stage; 4) rapid finalization of requirements; 5) early visualization of designs; 6) and a powerful vehicle for communication of the design to the programmers. Challenges included 1) time and effort to develop the prototypes and case scenarios; 2) no simulation of system performance; 3) not having all proposed functionality available in the final product; and 4) missing needed data elements in the PCC information system. PMID:27081404

  2. Search for ammonia in comet C/2012 S1 (ISON)

    NASA Astrophysics Data System (ADS)

    Faggi, S.; Codella, C.; Tozzi, G. P.; Comoretto, G.; Crovisier, J.; Nesti, R.; Panella, D.; Boissier, J.; Brucato, J. R.; Bolli, P.; Massi, F.; Tofani, G.

    2015-12-01

    Comets are uniquely pristine bodies providing unique insights about the formation of our Solar System. In this work, we focus on a dynamically new comet as it enters the inner Solar System for the first time after residing for billion of years in the Oort Cloud. Such comets are particularly important because they are thought to be not differentiated by solar radiation and they are supposed to have a large quantity of organic matter close to the surface. Here we report the results of a search for NH3(1,1) emission at 23.7 GHz towards comet C/2012 S1 (ISON) using a new dual-feed K band receiver mounted on the Medicina 32-m antenna. We observed the comet close to its perihelion, from 25 to 29 November 2013, when its heliocentric distance changed from 0.25 AU to 0.03 AU. We derive an upper limit of Q(NH3) of about 2.5×1029 mol s-1 on 26 November, that is consistent with the last peak of water production rate of ∼2×1030 mol s-1 within the last few days before the perihelion.

  3. Experimental design and analysis for irradiation of SiC/SiC composite tubes under a prototypic high heat flux

    NASA Astrophysics Data System (ADS)

    Petrie, Christian M.; Koyanagi, Takaaki; McDuffee, Joel L.; Deck, Christian P.; Katoh, Yutai; Terrani, Kurt A.

    2017-08-01

    The purpose of this work is to design an irradiation vehicle for testing silicon carbide (SiC) fiber-reinforced SiC matrix composite cladding materials under conditions representative of a light water reactor in order to validate thermo-mechanical models of stress states in these materials due to irradiation swelling and differential thermal expansion. The design allows for a constant tube outer surface temperature in the range of 300-350 °C under a representative high heat flux (∼0.66 MW/m2) during one cycle of irradiation in an un-instrumented ;rabbit; capsule in the High Flux Isotope Reactor. An engineered aluminum foil was developed to absorb the expansion of the cladding tubes, due to irradiation swelling, without changing the thermal resistance of the gap between the cladding and irradiation capsule. Finite-element analyses of the capsule were performed, and the models used to calculate thermal contact resistance were validated by out-of-pile testing and post-irradiation examination of the foils and passive SiC thermometry. Six irradiated cladding tubes (both monoliths and composites) were irradiated and subsequently disassembled in a hot cell. The calculated temperatures of passive SiC thermometry inside the capsules showed good agreement with temperatures measured post-irradiation, with two calculated temperatures falling within 10 °C of experimental measurements. The success of this design could lead to new opportunities for irradiation applications with materials that suffer from irradiation swelling, creep, or other dimensional changes that can affect the specimen temperature during irradiation.

  4. Experimental design and analysis for irradiation of SiC/SiC composite tubes under a prototypic high heat flux

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Petrie, Christian M.; Koyanagi, Takaaki; McDuffee, Joel L.

    The purpose of this work is to design an irradiation vehicle for testing silicon carbide (SiC) fiber-reinforced SiC matrix composite cladding materials under conditions representative of a light water reactor in order to validate thermo-mechanical models of stress states in these materials due to irradiation swelling and differential thermal expansion. The design allows for a constant tube outer surface temperature in the range of 300–350 °C under a representative high heat flux (~0.66 MW/m 2) during one cycle of irradiation in an un-instrumented “rabbit” capsule in the High Flux Isotope Reactor. An engineered aluminum foil was developed to absorb themore » expansion of the cladding tubes, due to irradiation swelling, without changing the thermal resistance of the gap between the cladding and irradiation capsule. Finite-element analyses of the capsule were performed, and the models used to calculate thermal contact resistance were validated by out-of-pile testing and post-irradiation examination of the foils and passive SiC thermometry. Six irradiated cladding tubes (both monoliths and composites) were irradiated and subsequently disassembled in a hot cell. The calculated temperatures of passive SiC thermometry inside the capsules showed good agreement with temperatures measured post-irradiation, with two calculated temperatures falling within 10 °C of experimental measurements. Furthermore, the success of this design could lead to new opportunities for irradiation applications with materials that suffer from irradiation swelling, creep, or other dimensional changes that can affect the specimen temperature during irradiation.« less

  5. Reactor Materials Program - Baseline Material Property Handbook - Mechanical Properties of 1950's Vintage Stainless Steel Weldment Components, Task Number 89-23-A-1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stoner, K.J.

    1999-11-05

    The Process Water System (primary coolant) piping of the nuclear production reactors constructed in the 1950''s at Savannah River Site is comprised primarily of Type 304 stainless steel with Type 308 stainless steel weld filler. A program to measure the mechanical properties of archival PWS piping and weld materials (having approximately six years of service at temperatures between 25 and 100 degrees C) has been completed. The results from the mechanical testing has been synthesized to provide a mechanical properties database for structural analyses of the SRS piping.

  6. NASA Reactor Facility Hazards Summary. Volume 1

    NASA Technical Reports Server (NTRS)

    1959-01-01

    The Lewis Research Center of the National Aeronautics and Space Administration proposes to build a nuclear research reactor which will be located in the Plum Brook Ordnance Works near Sandusky, Ohio. The purpose of this report is to inform the Advisory Committee on Reactor Safeguards of the U. S. Atomic Energy Commission in regard to the design Lq of the reactor facility, the characteristics of the site, and the hazards of operation at this location. The purpose of this research reactor is to make pumped loop studies of aircraft reactor fuel elements and other reactor components, radiation effects studies on aircraft reactor materials and equipment, shielding studies, and nuclear and solid state physics experiments. The reactor is light water cooled and moderated of the MTR-type with a primary beryllium reflector and a secondary water reflector. The core initially will be a 3 by 9 array of MTR-type fuel elements and is designed for operation up to a power of 60 megawatts. The reactor facility is described in general terms. This is followed by a discussion of the nuclear characteristics and performance of the reactor. Then details of the reactor control system are discussed. A summary of the site characteristics is then presented followed by a discussion of the larger type of experiments which may eventually be operated in this facility. The considerations for normal operation are concluded with a proposed method of handling fuel elements and radioactive wastes. The potential hazards involved with failures or malfunctions of this facility are considered in some detail. These are examined first from the standpoint of preventing them or minimizing their effects and second from the standpoint of what effect they might have on the reactor facility staff and the surrounding population. The most essential feature of the design for location at the proposed site is containment of the maximum credible accident.

  7. Biological oxidation of hydrogen sulfide in mineral media using a biofilm airlift suspension reactor.

    PubMed

    Moghanloo, G M Mojarrad; Fatehifar, E; Saedy, S; Aghaeifar, Z; Abbasnezhad, H

    2010-11-01

    Hydrogen sulfide (H(2)S) removal in mineral media using Thiobacillus thioparus TK-1 in a biofilm airlift suspension reactor (BAS) was investigated to evaluate the relationship between biofilm formation and changes in inlet loading rates. Aqueous sodium sulfide was fed as the substrate into the continuous BAS-reactor. The reactor was operated at a constant temperature of 30 degrees C and a pH of 7, the optimal temperature and pH for biomass growth. The startup of the reactor was performed with basalt carrier material. Optimal treatment performance was obtained at a loading rate of 4.8 mol S(2-) m(-3) h(-1) at a conversion efficiency as high as 100%. The main product of H(2)S oxidation in the BAS-reactor was sulfate because of high oxygen concentrations in the airlift reactor. The maximum sulfide oxidation rate was 6.7 mol S(2-) m(-3) h(-1) at a hydraulic residence time of 3.3 h in the mineral medium. The data showed that the BAS-reactor with this microorganism can be used for sulfide removal from industrial effluent. Copyright 2010 Elsevier Ltd. All rights reserved.

  8. Silica-Immobilized Enzyme Reactors; Application to Cholinesterase-Inhibition Studies

    DTIC Science & Technology

    2006-03-01

    a i a i e v b c a m p l 1 d Journal of Chromatography B, 843 (2006) 310–316 Silica-immobilized enzyme reactors; application to...however, have specific omat d t t i w i h c u C p R n t o t fl p f o l p d v t o s fl t t c t a b f c i h a t s m i b 2 2 ≈ c s 0 c A R I H l 2 b p a y ε c...b r T p d ( m 2 w

  9. TOPAZ II Anti-Criticality Device Rapid Prototype

    NASA Astrophysics Data System (ADS)

    Campbell, Donald R.; Otting, William D.

    1994-07-01

    The Ballistic Missile Defense Organization (BMDO) has been working on a Nuclear Electric Propulsion Space Test Project (NEPSTP) using an existing Russian Topaz II reactor system to power the NEPSTP satellite. Safety investigations have shown that it will be possible to safely launch the Topaz II system in the United States with some modification to preclude water flooded criticality. A ``fuel-out'' water subcriticality concept was selected by the Los Alamos National Laboratory (LANL) as the baseline concept. A fuel-out anti-criticality device (ACD) conceptual design was developed by Rockwell. The concept functions to hold the fuel from the four centermost thermionic fuel elements (TFEs) outside the reactor during launch and reliably inserts the fuel into the reactor once the operational orbit is achieved. A four-tenths scale ACD rapid prototype model, fabricated from the CATIA solids design model, clearly shows in three dimensions the relative size and spatial relationship of the ACD components.

  10. Improving High-Temperature Measurements in Nuclear Reactors with Mo/Nb Thermocouples

    NASA Astrophysics Data System (ADS)

    Villard, J.-F.; Fourrez, S.; Fourmentel, D.; Legrand, A.

    2008-10-01

    Many irradiation experiments performed in research reactors are used to assess the effects of nuclear radiations on material or fuel sample properties, and are therefore a crucial stage in most qualification and innovation studies regarding nuclear technologies. However, monitoring these experiments requires accurate and reliable instrumentation. Among all measurement systems implemented in irradiation devices, temperature—and more particularly high-temperature (above 1000°C)—is a major parameter for future experiments related, for example, to the Generation IV International Forum (GIF) Program or the International Thermonuclear Experimental Reactor (ITER) Project. In this context, the French Commissariat à l’Energie Atomique (CEA) develops and qualifies innovative in-pile instrumentation for its irradiation experiments in current and future research reactors. Logically, a significant part of these research and development programs concerns the improvement of in-pile high-temperature measurements. This article describes the development and qualification of innovative high-temperature thermocouples specifically designed for in-pile applications. This key study has been achieved with technical contributions from the Thermocoax Company. This new kind of thermocouple is based on molybdenum and niobium thermoelements, which remain nearly unchanged by thermal neutron flux even under harsh nuclear environments, whereas typical high-temperature thermocouples such as Type C or Type S are altered by significant drifts caused by material transmutations under the same conditions. This improvement has a significant impact on the temperature measurement capabilities for future irradiation experiments. Details of the successive stages of this development are given, including the results of prototype qualification tests and the manufacturing process.

  11. Detector evaluation of a prototype amorphous selenium-based full field digital mammography system

    NASA Astrophysics Data System (ADS)

    Jesneck, Jonathan L.; Saunders, Robert S.; Samei, Ehsan; Xia, Jessie Q.; Lo, Joseph Y.

    2005-04-01

    This study evaluated the physical performance of a selenium-based direct full-field digital mammography prototype detector (Siemens Mammomat NovationDR), including the pixel value vs. exposure linearity, the modulation transfer function (MTF), the normalized noise power spectrum (NNPS), and the detective quantum efficiency (DQE). The current detector is the same model which received an approvable letter from FDA for release to the US market. The results of the current prototype are compared to those of an earlier prototype. Two IEC standard beam qualities (RQA-M2: Mo/Mo, 28 kVp, 2 mm Al; RQA-M4: Mo/Mo, 35 kVp, 2 mm Al) and two additional beam qualities (MW2: W/Rh, 28 kVp, 2 mm Al; MW4: W/Rh, 35 kVp, 2 mm Al) were investigated. To calculate the modulation transfer function (MTF), a 0.1 mm Pt-Ir edge was imaged at each beam quality. Detector pixel values responded linearly against exposure values (R2 0.999). As before, above 6 cycles/mm Mo/Mo MTF was slightly higher along the chest-nipple axis compared to the left-right axis. MTF was comparable to the previously reported prototype, with slightly reduced resolution. The DQE peaks ranged from 0.71 for 3.31 μC/kg (12.83 mR) to 0.4 for 0.48 μC/kg (1.86 mR) at 1.75 cycles/mm for Mo/Mo at 28 kVp. The DQE range for W/Rh at 28 kVP was 0.81 at 2.03 μC/kg (7.87 mR) to 0.50 at 0.50 μC/kg (1.94 mR) at 1 cycle/mm. NNPS tended to increase with greater exposures, while all exposures had a significant low-frequency component. Bloom and detector edge artifacts observed previously were no longer present in this prototype. The new detector shows marked noise improvement, with slightly reduced resolution. There remain artifacts due to imperfect gain calibration, but at a reduced magnitude compared to a prototype detector.

  12. Final report, PT IP-535-C: Test of smaller VSR`s in DR reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vaughn, A.D.

    1963-04-17

    Because of rod-sticking problems at DR Reactor, a knuckle rod of B Reactor design was installed in vertical safety channel number 28. The substitute VSR, which has a smaller diameter than the original DR rod, has been tested for its operational feasibility including both drop time and reactivity effect. The reactivity effect of the rod was estimated by comparison of the reactivity transient caused by insertion of the specific B-type rod after scramming into the pile, with similar transients caused by normal vertical safety rod in an adjacent channel. This document lists the indicated relative control strength of the rodmore » as an empirical basis for future safety calculations. Results indicate that the B-type knuckel rod in DR reactor is about 80% as strong as a normal DR vertical safety rod if used in equivalent flux distribution and location; this makes it reasonable to assume that the local control strength of the B-type knuckel rod is 98 {mu}b.« less

  13. 10 CFR 1.43 - Office of Nuclear Reactor Regulation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Office of Nuclear Reactor Regulation. 1.43 Section 1.43 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Headquarters Program Offices § 1.43 Office of Nuclear Reactor Regulation. The Office of Nuclear Reactor Regulation— (a...

  14. 10 CFR 1.43 - Office of Nuclear Reactor Regulation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Office of Nuclear Reactor Regulation. 1.43 Section 1.43 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Headquarters Program Offices § 1.43 Office of Nuclear Reactor Regulation. The Office of Nuclear Reactor Regulation— (a...

  15. 10 CFR 1.43 - Office of Nuclear Reactor Regulation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Office of Nuclear Reactor Regulation. 1.43 Section 1.43 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Headquarters Program Offices § 1.43 Office of Nuclear Reactor Regulation. The Office of Nuclear Reactor Regulation— (a...

  16. 10 CFR 1.43 - Office of Nuclear Reactor Regulation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Office of Nuclear Reactor Regulation. 1.43 Section 1.43 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Headquarters Program Offices § 1.43 Office of Nuclear Reactor Regulation. The Office of Nuclear Reactor Regulation— (a...

  17. 10 CFR 1.43 - Office of Nuclear Reactor Regulation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Office of Nuclear Reactor Regulation. 1.43 Section 1.43 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Headquarters Program Offices § 1.43 Office of Nuclear Reactor Regulation. The Office of Nuclear Reactor Regulation— (a...

  18. Microsatellite-based fine mapping of the Van der Woude syndrome locus to an interval of 4.1 cM between D1S245 and D1S414

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sander, A.; Schmelzle, R.; Murray, J.C.

    1995-01-01

    Van der Woude syndrome (VWS) is an autosomal dominant craniofacial disorder characterized by lip pits, clefting of the primary or secondary palate, and hypodontia. The gene has been localized, by RFLP-based linkage studies, to region 1q32-41 between D1S65-REN and D1S65-TGFB2. In this study we report the linkage analysis of 15 VWS families, using 18 microsatellite markers. Multipoint linkage analysis places the gene, with significant odds of 2,344:1, in a 4.1-cM interval flanked by D1S245 and D1S414. Two-point linkage analysis demonstrates close linkage of VWS with D1S205 (lod score [Z] = 24.41 at {theta} = .00) and with D1S491 (Z =more » 21.23 at {theta} = .00). The results revise the previous assignment of the VWS locus and show in an integrated map of the region 1q32-42 that the VWS gene resides more distally than previously suggested. When information about heterozygosity of the closely linked marker D1S491 in the affected members of the VWS family with a microdeletion is taken into account, the VWS critical region can be further narrowed, to the 3.6-cM interval between D1S491 and D1S414. 38 refs., 3 figs., 2 tabs.« less

  19. Measurement of 14C emission rates from a pressurised heavy water reactor.

    PubMed

    Joshi, M L; Ramamirtham, B; Soman, S D

    1987-06-01

    Carbon-14 is produced in pressurised heavy water reactors (PHWR), mainly as an activation product in the fuel. It is also produced in the heavy water used as the primary coolant and moderator, and is produced in the air in the annular space between the pressure tube and calandria tubes as well as in the free space in the calandria vault. The production rates in different systems of a PHWR are calculated on the basis of design parameters. During a period of 3 y, 14C released through the gaseous route has been measured at Rajasthan Atomic Power Station, Kota, India, a PHWR unit. These releases have been found to be mainly 14CO2. This reduced form of 14C is less than 5% of the releases. The normalised releases of 14C have a geometric mean of 5.17 TBq GWe-1 y-1 and a geometric standard deviation of 1.52. The 14C present in the form of carbonates in liquid effluents has also been measured and is 0.14% of the gaseous releases.

  20. Where does the removal of H₂S from biogas occur in microaerobic reactors?

    PubMed

    Ramos, I; Peña, M; Fdz-Polanco, M

    2014-08-01

    In order to maximise the efficiency of biogas desulphurisation and reduce the oxygen cost during microaerobic digestion, it is essential to know how the process occurs. For this purpose, a reactor with a total volume of 266 L, treating 10 L/d of sewage sludge, was operated with 25.0 L and without headspace. Under anaerobic conditions, the H2S concentration in the biogas varied between 0.21 and 0.38%v/v. Next, O2 was supplied from the bottom of the reactor. At 0.25-0.30 NLO₂/Lfed, the biogas was entirely desulphurised, and its O₂ content remained below 1.03%v/v, when the digester had 25.0 L of gas space. However, with almost no headspace, the H2S content in the biogas fluctuated from 0.08 to 0.21%v/v, while the average O2 concentration was 1.66%v/v. The removed H2S accumulated in the outlet pipe of the biogas in the form of S(0) due to the insufficient headspace. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Alcohol binding in the C1 (C1A + C1B) domain of protein kinase C epsilon

    PubMed Central

    Pany, Satyabrata; Das, Joydip

    2015-01-01

    Background Alcohol regulates the expression and function of protein kinase C epsilon (PKCε). In a previous study we identified an alcohol binding site in the C1B, one of the twin C1 subdomains of PKCε. Methods In this study, we investigated alcohol binding in the entire C1 domain (combined C1A and C1B) of PKCε. Fluorescent phorbol ester, SAPD and fluorescent diacylglycerol (DAG) analog, dansyl-DAG were used to study the effect of ethanol, butanol, and octanol on the ligand binding using fluorescence resonance energy transfer (FRET). To identify alcohol binding site(s), PKCεC1 was photolabeled with 3-azibutanol and 3-azioctanol, and analyzed by mass spectrometry. The effects of alcohols and the azialcohols on PKCε were studied in NG108-15 cells. Results In the presence of alcohol, SAPD and dansyl-DAG showed different extent of FRET, indicating differential effects of alcohol on the C1A and C1B subdomains. Effects of alcohols and azialcohols on PKCε in NG108-15 cells were comparable. Azialcohols labeled Tyr-176 of C1A and Tyr-250 of C1B. Inspection of the model structure of PKCεC1 reveals that these residues are 40 Å apart from each other indicating that these residues form two different alcohol binding sites. Conclusions The present results provide evidence for the presence of multiple alcohol-binding sites on PKCε and underscore the importance of targeting this PKC isoform in developing alcohol antagonists. PMID:26210390

  2. Cooling Performance Analysis of ThePrimary Cooling System ReactorTRIGA-2000Bandung

    NASA Astrophysics Data System (ADS)

    Irianto, I. D.; Dibyo, S.; Bakhri, S.; Sunaryo, G. R.

    2018-02-01

    The conversion of reactor fuel type will affect the heat transfer process resulting from the reactor core to the cooling system. This conversion resulted in changes to the cooling system performance and parameters of operation and design of key components of the reactor coolant system, especially the primary cooling system. The calculation of the operating parameters of the primary cooling system of the reactor TRIGA 2000 Bandung is done using ChemCad Package 6.1.4. The calculation of the operating parameters of the cooling system is based on mass and energy balance in each coolant flow path and unit components. Output calculation is the temperature, pressure and flow rate of the coolant used in the cooling process. The results of a simulation of the performance of the primary cooling system indicate that if the primary cooling system operates with a single pump or coolant mass flow rate of 60 kg/s, it will obtain the reactor inlet and outlet temperature respectively 32.2 °C and 40.2 °C. But if it operates with two pumps with a capacity of 75% or coolant mass flow rate of 90 kg/s, the obtained reactor inlet, and outlet temperature respectively 32.9 °C and 38.2 °C. Both models are qualified as a primary coolant for the primary coolant temperature is still below the permitted limit is 49.0 °C.

  3. A prototype hybrid 7π quinone-fused 1,3,2-dithiazolyl radical.

    PubMed

    Decken, A; Mailman, A; Passmore, J; Rautiainen, J M; Scherer, W; Scheidt, E-W

    2011-01-28

    Reaction of 1,4-naphthoquinone and SNSMF(6) (M = As, Sb) in SO(2) solution in a 1 : 2 molar ratio led to the naphthoquinone fused 1,3,2-dithiazolylium salts, 3MF(6) quantitatively by multinuclear NMR (87% isolated yield of 3SbF(6)) via the cycloaddition and oxidative dehydrogenation chemistry of SNS(+) with formation of NH(4)SbF(6) and S(8). The product 3SbF(6) was fully characterized by IR, Raman, multinuclear {(1)H, (13)C, (14)N} NMR, elemental analysis, cyclic voltammetry and single crystal X-ray crystallography. The reduction of 3SbF(6) with ferrocene (Cp(2)Fe) in refluxing acetonitrile (CH(3)CN) led to the first isolation of a fused quinone-thiazyl radical, 3˙ in 73% yield. The prototype hybrid quinone-thiazyl radical 3˙ was fully characterized by IR, Raman microscopy, EI-MS, elemental analysis, solution and solid state EPR, magnetic susceptibility (2-370 K) and was found to form π*-π* dimers in the solid state as determined by single crystal X-ray crystallography. Furthermore, the thermal decomposition of 3˙ led to a novel quinone-fused 1,2,3,4-tetrathiine, 10 (x = 2) and the known 1,2,5-thiadiazole, 11. The energetics of the cycloadditon and oxidative dehydrogenation chemistry of SNS(+) and 1,4-naphthoquinone leading to 3SbF(6) were estimated in the gas phase and SO(2) solution by DFT calculations (PBE0/6-311G(d)) and lattice enthalpies obtained by the volume based thermodynamic (VBT) approach in the solid state. The gas phase ion energetics (ionization potential (IP) and electron affinity (EA)) of 3˙ are compared to related 1,3,2- and 1,2,3-dithiazolyl radicals.

  4. A Graphics Environment Supporting the Rapid Prototyping of Pictorial Cockpit Displays

    DTIC Science & Technology

    1986-12-01

    0 - niDi cO 3 FIL .OF I A GRAPHICS ENVIRONMENT SUPPORTING THE RAPID PROTOTYPING OF PICTORIAL COCKPIT DISPLAYS THESIS Alan J. Braaten Captain, USAF...COCKPIT DISPLAYS THESIS Alan J. Braaten Captain, USAF AFIT/GCS/IA/86D- 1 Appram:ed for public release; distribution unlimited AFIT/GCS/MA/80- 1 A...GRAPHICS ENVIROWNT SUPPORTING THE RAPID PROTOTYPING OF PICTORIAL COCKPIT DISPLAYS THESIS Preented to the Faculty Of the School of Engineering of the Air

  5. 10 CFR 72.108 - Spent fuel, high-level radioactive waste, or reactor-related greater than Class C waste...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Spent fuel, high-level radioactive waste, or reactor... RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Siting Evaluation Factors § 72.108 Spent fuel, high-level radioactive waste, or reactor-related greater than Class C waste transportation. The...

  6. 10 CFR 72.108 - Spent fuel, high-level radioactive waste, or reactor-related greater than Class C waste...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Spent fuel, high-level radioactive waste, or reactor... RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Siting Evaluation Factors § 72.108 Spent fuel, high-level radioactive waste, or reactor-related greater than Class C waste transportation. The...

  7. VizieR Online Data Catalog: C/2012 F6 (Lemmon) and C/2012 S1 (ISON) maps (Cordiner+, 2014)

    NASA Astrophysics Data System (ADS)

    Cordiner, M. A.; Remijan, A. J.; Boissier, J.; Milam, S. N.; Mumma, M. J.; Charnley, S. B.; Paganini, L.; Villanueva, G.; Bockelee-Morvan, D.; Kuan, Y.-J.; Chuang, Y.-L.; Lis, D. C.; Biver, N.; Crovisier, J.; Minniti, D.; Coulson, I. M.

    2017-04-01

    WCS-calibrated fits image files of the molecular flux maps shown in Figure 1 for HCN, HNC and H2CO observed in comets C/2012 F6 (Lemmon) and C/2012 S1 (ISON) using ALMA. The files are labeled with the corresponding comet and molecule names. The files are standard two-dimensional fits images, which can be opened in fits image viewers such as SAOimage DS9, CASA viewer, or Starlink Gaia. GIMP and Adobe Photoshop can also be used, provided the appropriate plugins are present. The images contain flux values (in units of Jansky km/s per beam), as a function of celestial coordinate in the J2000 equatorial system. Due to the cometary motions, the absolute coordinate systems are accurate only at the start of the observations (dates and times are given in Table 1). These images are the result of integrating the (3D) ALMA data cubes over the full widths of the observed spectral lines (equivalent to collapsing the data cubes along their respective spectral/velocity axes). The beam dimensions (BMAJ and BMIN), corresponding to the angular resolution of the images, are given in the image headers in units of degrees. object.dat : -------------------------------------------------------------------------------- Code Name Elem q e i H1 d AU deg mag -------------------------------------------------------------------------------- C/2012 F6 Lemmon 2456375.5 0.7312461 0.9985125 82.607966 7.96 C/2012 S1 Ison 2456624.5 0.0124515 0.9998921 64.401571 6.11 (2 data files).

  8. 10 CFR 1.13 - Advisory Committee on Reactor Safeguards.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Advisory Committee on Reactor Safeguards. 1.13 Section 1... Headquarters Panels, Boards, and Committees § 1.13 Advisory Committee on Reactor Safeguards. The Advisory Committee on Reactor Safeguards (ACRS) was established by section 29 of the Atomic Energy Act of 1954, as...

  9. 10 CFR 1.13 - Advisory Committee on Reactor Safeguards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Advisory Committee on Reactor Safeguards. 1.13 Section 1... Headquarters Panels, Boards, and Committees § 1.13 Advisory Committee on Reactor Safeguards. The Advisory Committee on Reactor Safeguards (ACRS) was established by section 29 of the Atomic Energy Act of 1954, as...

  10. Prototype development and demonstration for response, emergency staging, communications, uniform management, and evacuation (R.E.S.C.U.M.E.) : technical report on prototype development and field testing of R.E.S.C.U.M.E. applications.

    DOT National Transportation Integrated Search

    2015-04-01

    This document is the final project technical report for the development and field testing of the Response, Emergency Staging, Communications, Uniform Management, and Evacuation (R.E.S.C.U.M.E.) application bundle, with a focus on the Incident Zone (I...

  11. Comparison of Newly Assembled Full Length HIV-1 Integrase With Prototype Foamy Virus Integrase: Structure-Function Prospective.

    PubMed

    Dayer, Mohammad Reza

    2016-05-01

    Drug design against human immunodeficiency virus type 1 (HIV-1) integrase through its mechanistic study is of great interest in the area in biological research. The main obstacle in this area is the absence of the full-length crystal structure for HIV-1 integrase to be used as a model. A complete structure, similar to HIV-1 of a prototype foamy virus integrase in complex with DNA, including all conservative residues, is available and has been extensively used in recent investigations. The aim of this study was to determine whether the above model is precisely representative of HIV-1 integrase. This would critically determine the success of any designed drug using the model in deactivation of integrase and AIDS treatment. Primarily, a new structure for HIV-1 was constructed, using a crystal structure of prototype foamy virus as the starting structure. The constructed structure of HIV-1 integrase was simultaneously simulated with a prototype foamy virus integrase on a separate occasion. Our results indicate that the HIV-1 system behaves differently from the prototype foamy virus in terms of folding, hydration, hydrophobicity of binding site and stability. Based on our findings, we can conclude that HIV-1 integrase is vastly different from the prototype foamy virus integrase and does not resemble it, and the modeling output of the prototype foamy virus simulations could not be simply generalized to HIV-1 integrase. Therefore, our HIV-1 model seems to be more representative and more useful for future research.

  12. Reconceiving ISD: Three Perspectives on Rapid Prototyping as a Paradigm Shift.

    ERIC Educational Resources Information Center

    Rathbun, Gail A.; And Others

    Confronting recent design challenges, instructional designers have latched onto adaptive procedural techniques from outside the Instructional Systems Design (ISD) field. This discussion of rapid prototyping (RP) examines the perspectives of: (1) the prototype as the designer"s cognitive tool; (2) the designer as co-inquirer; and (3) the…

  13. Mechanical properties of SiC composites neutron irradiated under light water reactor relevant temperature and dose conditions

    DOE PAGES

    Koyanagi, Takaaki; Katoh, Yutai

    2017-07-04

    Silicon carbide (SiC) fiber–reinforced SiC matrix (SiC/SiC) composites are being actively investigated for use in accident-tolerant core structures of light water reactors (LWRs). Owing to the limited number of irradiation studies previously conducted at LWR-coolant temperature, this paper examined SiC/SiC composites following neutron irradiation at 230–340 °C to 2.0 and 11.8 dpa in the High Flux Isotope Reactor. The investigated materials were chemical vapor infiltrated (CVI) SiC/SiC composites with three different reinforcement fibers. The fiber materials were monolayer pyrolytic carbon (PyC) -coated Hi-Nicalon™ Type-S (HNS), Tyranno™ SA3 (SA3), and SCS-Ultra™ (SCS) SiC fibers. The irradiation resistance of these composites wasmore » investigated based on flexural behavior, dynamic Young's modulus, swelling, and microstructures. There was no notable mechanical properties degradation of the irradiated HNS and SA3 SiC/SiC composites except for reduction of the Young's moduli by up to 18%. The microstructural stability of these composites supported the absence of degradation. In addition, no progressive swelling from 2.0 to 11.8 dpa was confirmed for these composites. On the other hand, the SCS composite showed significant mechanical degradation associated with cracking within the fiber. Finally, this study determined that SiC/SiC composites with HNS or SA3 SiC/SiC fibers, a PyC interphase, and a CVI SiC matrix retain their properties beyond the lifetime dose for LWR fuel cladding at the relevant temperature.« less

  14. Mechanical properties of SiC composites neutron irradiated under light water reactor relevant temperature and dose conditions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koyanagi, Takaaki; Katoh, Yutai

    Silicon carbide (SiC) fiber–reinforced SiC matrix (SiC/SiC) composites are being actively investigated for use in accident-tolerant core structures of light water reactors (LWRs). Owing to the limited number of irradiation studies previously conducted at LWR-coolant temperature, this paper examined SiC/SiC composites following neutron irradiation at 230–340 °C to 2.0 and 11.8 dpa in the High Flux Isotope Reactor. The investigated materials were chemical vapor infiltrated (CVI) SiC/SiC composites with three different reinforcement fibers. The fiber materials were monolayer pyrolytic carbon (PyC) -coated Hi-Nicalon™ Type-S (HNS), Tyranno™ SA3 (SA3), and SCS-Ultra™ (SCS) SiC fibers. The irradiation resistance of these composites wasmore » investigated based on flexural behavior, dynamic Young's modulus, swelling, and microstructures. There was no notable mechanical properties degradation of the irradiated HNS and SA3 SiC/SiC composites except for reduction of the Young's moduli by up to 18%. The microstructural stability of these composites supported the absence of degradation. In addition, no progressive swelling from 2.0 to 11.8 dpa was confirmed for these composites. On the other hand, the SCS composite showed significant mechanical degradation associated with cracking within the fiber. Finally, this study determined that SiC/SiC composites with HNS or SA3 SiC/SiC fibers, a PyC interphase, and a CVI SiC matrix retain their properties beyond the lifetime dose for LWR fuel cladding at the relevant temperature.« less

  15. Mechanical properties of SiC composites neutron irradiated under light water reactor relevant temperature and dose conditions

    NASA Astrophysics Data System (ADS)

    Koyanagi, Takaaki; Katoh, Yutai

    2017-10-01

    Silicon carbide (SiC) fiber-reinforced SiC matrix (SiC/SiC) composites are being actively investigated for use in accident-tolerant core structures of light water reactors (LWRs). Owing to the limited number of irradiation studies previously conducted at LWR-coolant temperature, this study examined SiC/SiC composites following neutron irradiation at 230-340 °C to 2.0 and 11.8 dpa in the High Flux Isotope Reactor. The investigated materials were chemical vapor infiltrated (CVI) SiC/SiC composites with three different reinforcement fibers. The fiber materials were monolayer pyrolytic carbon (PyC) -coated Hi-Nicalon™ Type-S (HNS), Tyranno™ SA3 (SA3), and SCS-Ultra™ (SCS) SiC fibers. The irradiation resistance of these composites was investigated based on flexural behavior, dynamic Young's modulus, swelling, and microstructures. There was no notable mechanical properties degradation of the irradiated HNS and SA3 SiC/SiC composites except for reduction of the Young's moduli by up to 18%. The microstructural stability of these composites supported the absence of degradation. In addition, no progressive swelling from 2.0 to 11.8 dpa was confirmed for these composites. On the other hand, the SCS composite showed significant mechanical degradation associated with cracking within the fiber. This study determined that SiC/SiC composites with HNS or SA3 SiC/SiC fibers, a PyC interphase, and a CVI SiC matrix retain their properties beyond the lifetime dose for LWR fuel cladding at the relevant temperature.

  16. Remediation of 1,2,3-trichlorobenzene contaminated soil using a combined thermal desorption-molten salt oxidation reactor system.

    PubMed

    Li, Jin-hui; Sun, Xiao-fei; Yao, Zhi-tong; Zhao, Xiang-yang

    2014-02-01

    A combined thermal desorption (TD)-molten salt oxidation (MSO) reactor system was applied to remediate the 1,2,3-trichlorobenzene (1,2,3-TCB) contaminated soil. The TD reactor was used to enrich the contaminant from soil, and its dechlorination of the contaminant was achieved in the MSO reactor. The optimum operating conditions of TD, and the effects of MSO reactor temperatures, additive amounts of the TCB on destruction and removal efficiency (DRE) of TCB and chlorine retention efficiency (CRE) were investigated. The reaction mechanism and pathway were proposed as well. The combined system could remediate the contaminated soil at a large scale of concentration from 5 to 25gkg(-1), and the DRE and CRE reached more than 99% and 95%, respectively, at temperatures above 850°C. The reaction emissions included C6H6, CH4, CO and CO2, and chlorinated species were not detected. It was found that a little increase in the temperature can considerably reduce the emission of C6H6, CH4, and CO, while the CO2 level increased. Copyright © 2014. Published by Elsevier Ltd.

  17. Performance and microbial community composition dynamics of aerobic granular sludge from sequencing batch bubble column reactors operated at 20 degrees C, 30 degrees C, and 35 degrees C.

    PubMed

    Ebrahimi, Sirous; Gabus, Sébastien; Rohrbach-Brandt, Emmanuelle; Hosseini, Maryam; Rossi, Pierre; Maillard, Julien; Holliger, Christof

    2010-07-01

    Two bubble column sequencing batch reactors fed with an artificial wastewater were operated at 20 degrees C, 30 degrees C, and 35 degrees C. In a first stage, stable granules were obtained at 20 degrees C, whereas fluffy structures were observed at 30 degrees C. Molecular analysis revealed high abundance of the operational taxonomic unit 208 (OTU 208) affiliating with filamentous bacteria Leptothrix spp. at 30 degrees C, an OTU much less abundant at 20 degrees C. The granular sludge obtained at 20 degrees C was used for the second stage during which one reactor was maintained at 20 degrees C and the second operated at 30 degrees C and 35 degrees C after prior gradual increase of temperature. Aerobic granular sludge with similar physical properties developed in both reactors but it had different nutrient elimination performances and microbial communities. At 20 degrees C, acetate was consumed during anaerobic feeding, and biological phosphorous removal was observed when Rhodocyclaceae-affiliating OTU 214 was present. At 30 degrees C and 35 degrees C, acetate was mainly consumed during aeration and phosphorous removal was insignificant. OTU 214 was almost absent but the Gammaproteobacteria-affiliating OTU 239 was more abundant than at 20 degrees C. Aerobic granular sludge at all temperatures contained abundantly the OTUs 224 and 289 affiliating with Sphingomonadaceae indicating that this bacterial family played an important role in maintaining stable granular structures.

  18. Search for ammonia in comet C/2012 S1 (ISON)

    NASA Astrophysics Data System (ADS)

    Faggi, S.; Codella, C.; Tozzi, G.; Comoretto, G.; Crovisier, J.; Nesti, R.; Panella, D.; Boissier, J.; Bolli, P.; Brucato, J.; Massi, F.; Tofani, G.

    2014-07-01

    Comets are pristine bodies of the Solar System and their studies can give precious hints on the formation of the Solar System itself. New comets, coming form the Oort Colud at their first passage close to the Sun, are particularly important, because they are not differentiated by the Solar radiation and they are supposed to have a large quantity of organic matter close to the surface. Here we report the results of a search for NH_3(1,1) emission at 23.7 GHz in comet C/2012 S1 ISON using a new dual-feed K-band receiver mounted on the Medicina 32-m antenna. We observed the comet once close to its perihelion, from 2013 Nov. 25 to Nov. 28, when its heliocentric distance changed from 0.25 au to 0.03 au. We integrated about 6 hrs per day, obtaining high-spectral-resolution (1 km/s) spectra with a typical rms noise of 10 mK. Such sensitivity allowed us to derive an upper limit of Q(NH_3) of about 2.5 ×10^{29} mol/s on November 26. This upper limit would correspond to a Q(H_2O) of about 2.5 ×10^{31} mol/s, assuming the typical Q(H_2O)/Q(NH_3) ratio of 100. These findings confirm that no significant Q(H_2O) enhancement happened near the perihelion, consistent with a definitive decrease of molecules production rate.

  19. Identification of tertiary butyl alcohol (TBA)-utilizing organisms in BioGAC reactors using 13C-DNA stable isotope probing.

    PubMed

    Aslett, Denise; Haas, Joseph; Hyman, Michael

    2011-09-01

    Biodegradation of the gasoline oxygenates methyl tertiary-butyl ether (MTBE) and ethyl tertiary-butyl ether (ETBE) can cause tertiary butyl alcohol (TBA) to accumulate in gasoline-impacted environments. One remediation option for TBA-contaminated groundwater involves oxygenated granulated activated carbon (GAC) reactors that have been self-inoculated by indigenous TBA-degrading microorganisms in ground water extracted from contaminated aquifers. Identification of these organisms is important for understanding the range of TBA-metabolizing organisms in nature and for determining whether self-inoculation of similar reactors is likely to occur at other sites. In this study (13)C-DNA-stable isotope probing (SIP) was used to identify TBA-utilizing organisms in samples of self-inoculated BioGAC reactors operated at sites in New York and California. Based on 16S rRNA nucleotide sequences, all TBA-utilizing organisms identified were members of the Burkholderiales order of the β-proteobacteria. Organisms similar to Cupriavidus and Methylibium were observed in both reactor samples while organisms similar to Polaromonas and Rhodoferax were unique to the reactor sample from New York. Organisms similar to Hydrogenophaga and Paucibacter strains were only detected in the reactor sample from California. We also analyzed our samples for the presence of several genes previously implicated in TBA oxidation by pure cultures of bacteria. Genes Mpe_B0532, B0541, B0555, and B0561 were all detected in (13)C-metagenomic DNA from both reactors and deduced amino acid sequences suggested these genes all encode highly conserved enzymes. One gene (Mpe_B0555) encodes a putative phthalate dioxygenase-like enzyme that may be particularly appropriate for determining the potential for TBA oxidation in contaminated environmental samples.

  20. Possible Dust Models for C/2012 S1

    NASA Astrophysics Data System (ADS)

    Yanamandra-Fisher, P. A.

    2014-12-01

    Comet C/2012 S1 (ISON) provided a great opportunity to study a dynamically new Oort-cloud comet on its initial and only passage through the inner solar system. Contrary to expectations, the comet's activity fluctuated from high through a quiescent phase, and a major outburst days before its perihelion passage, ending in a dramatic race to complete disintegration on perihelion day, 28 November 2013. Amateur observations to professional ground-based, sub-orbital telescopes indicate the various changes of visible factors such as Afrho, a proxy for dust activity, and the measured production rates for water, consistent with the disintegration of the nucleus. Hines et al. (2013; ApJ Lett. 780) detected positive polarization in the inner coma and negative polarization in the outer coma, indicative of a jet, independently confirmed by Li et al. (2013, ApJ Lett., 779). Thermal emission observations of the comet pre-perihelion from NAOJ/Subaru/COMICS, a mid-infrared spectrometer, indicated a body with an equivalent brightness temperature of 265K (Ootsubo et al., 2013, ACM, Helsinki,FI); thermal observations acquired at the NASA/Infrared Telescope Facility (IRTF) with The Aerospace Corporation spectrometer (BASS, PI. R. Russell), before and after the November 12, 2013 outburst observed by the CIOC_ISON amateur network, indicates a brightness temperature of 330K and the presence, albeit weak, of the 11.3-micron crystalline silicate feature (Sitko et al., 2014, LPI abstract 1537). A Monte Carlo comet dust tail model, applied to extract the dust environment parameters of comet C/2012 S1 (ISON) from both Earth-based and Solar and Heliospheric Observatory (SOHO) calibrated observations, performed from about 6 AU (inbound), to right after perihelion passage, when just a small portion of the original comet nucleus survived in the form of a cloud of tiny particles, indicates that particles underwent disintegration and fragmentation (Moreno et al., 2014, ApJ Lett., 791). Ongoing work

  1. Automated Work Packages Prototype: Initial Design, Development, and Evaluation. Light Water Reactor Sustainability Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Oxstrand, Johanna Helene; Ahmad Al Rashdan; Le Blanc, Katya Lee

    The goal of the Automated Work Packages (AWP) project is to demonstrate how to enhance work quality, cost management, and nuclear safety through the use of advanced technology. The work described in this report is part of the digital architecture for a highly automated plant project of the technical program plan for advanced instrumentation, information, and control (II&C) systems technologies. This report addresses the DOE Milestone M2LW-15IN0603112: Describe the outcomes of field evaluations/demonstrations of the AWP prototype system and plant surveillance and communication framework requirements at host utilities. A brief background to the need for AWP research is provided, thenmore » two human factors field evaluation studies are described. These studies focus on the user experience of conducting a task (in this case a preventive maintenance and a surveillance test) while using an AWP system. The remaining part of the report describes an II&C effort to provide real time status updates to the technician by wireless transfer of equipment indications and a dynamic user interface.« less

  2. Titer-plate formatted continuous flow thermal reactors: Design and performance of a nanoliter reactor

    PubMed Central

    Chen, Pin-Chuan; Park, Daniel S.; You, Byoung-Hee; Kim, Namwon; Park, Taehyun; Soper, Steven A.; Nikitopoulos, Dimitris E.; Murphy, Michael C.

    2010-01-01

    Arrays of continuous flow thermal reactors were designed, configured, and fabricated in a 96-device (12 × 8) titer-plate format with overall dimensions of 120 mm × 96 mm, with each reactor confined to a 8 mm × 8 mm footprint. To demonstrate the potential, individual 20-cycle (740 nL) and 25-cycle (990 nL) reactors were used to perform the continuous flow polymerase chain reaction (CFPCR) for amplification of DNA fragments of different lengths. Since thermal isolation of the required temperature zones was essential for optimal biochemical reactions, three finite element models, executed with ANSYS (v. 11.0, Canonsburg, PA), were used to characterize the thermal performance and guide system design: (1) a single device to determine the dimensions of the thermal management structures; (2) a single CFPCR device within an 8 mm × 8 mm area to evaluate the integrity of the thermostatic zones; and (3) a single, straight microchannel representing a single loop of the spiral CFPCR device, accounting for all of the heat transfer modes, to determine whether the PCR cocktail was exposed to the proper temperature cycling. In prior work on larger footprint devices, simple grooves between temperature zones provided sufficient thermal resistance between zones. For the small footprint reactor array, 0.4 mm wide and 1.2 mm high fins were necessary within the groove to cool the PCR cocktail efficiently, with a temperature gradient of 15.8°C/mm, as it flowed from the denaturation zone to the renaturation zone. With temperature tolerance bands of ±2°C defined about the nominal temperatures, more than 72.5% of the microchannel length was located within the desired temperature bands. The residence time of the PCR cocktail in each temperature zone decreased and the transition times between zones increased at higher PCR cocktail flow velocities, leading to less time for the amplification reactions. Experiments demonstrated the performance of the CFPCR devices as a function of flow

  3. Convective cooling in a pool-type research reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sipaun, Susan, E-mail: susan@nm.gov.my; Usman, Shoaib, E-mail: usmans@mst.edu

    2016-01-22

    A reactor produces heat arising from fission reactions in the nuclear core. In the Missouri University of Science and Technology research reactor (MSTR), this heat is removed by natural convection where the coolant/moderator is demineralised water. Heat energy is transferred from the core into the coolant, and the heated water eventually evaporates from the open pool surface. A secondary cooling system was installed to actively remove excess heat arising from prolonged reactor operations. The nuclear core consists of uranium silicide aluminium dispersion fuel (U{sub 3}Si{sub 2}Al) in the form of rectangular plates. Gaps between the plates allow coolant to passmore » through and carry away heat. A study was carried out to map out heat flow as well as to predict the system’s performance via STAR-CCM+ simulation. The core was approximated as porous media with porosity of 0.7027. The reactor is rated 200kW and total heat density is approximately 1.07+E7 Wm{sup −3}. An MSTR model consisting of 20% of MSTR’s nuclear core in a third of the reactor pool was developed. At 35% pump capacity, the simulation results for the MSTR model showed that water is drawn out of the pool at a rate 1.28 kg s{sup −1} from the 4” pipe, and predicted pool surface temperature not exceeding 30°C.« less

  4. 77 FR 67688 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Digital I&C...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-13

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Digital I&C; Notice of Meeting The ACRS Subcommittee on Digital I&C will hold a meeting on November 16, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open...

  5. C1q Protein Binds to the Apoptotic Nucleolus and Causes C1 Protease Degradation of Nucleolar Proteins*

    PubMed Central

    Cai, Yitian; Teo, Boon Heng Dennis; Yeo, Joo Guan; Lu, Jinhua

    2015-01-01

    In infection, complement C1q recognizes pathogen-congregated antibodies and elicits complement activation. Among endogenous ligands, C1q binds to DNA and apoptotic cells, but whether C1q binds to nuclear DNA in apoptotic cells remains to be investigated. With UV irradiation-induced apoptosis, C1q initially bound to peripheral cellular regions in early apoptotic cells. By 6 h, binding concentrated in the nuclei to the nucleolus but not the chromatins. When nucleoli were isolated from non-apoptotic cells, C1q also bound to these structures. In vivo, C1q exists as the C1 complex (C1qC1r2C1s2), and C1q binding to ligands activates the C1r/C1s proteases. Incubation of nucleoli with C1 caused degradation of the nucleolar proteins nucleolin and nucleophosmin 1. This was inhibited by the C1 inhibitor. The nucleoli are abundant with autoantigens. C1q binding and C1r/C1s degradation of nucleolar antigens during cell apoptosis potentially reduces autoimmunity. These findings help us to understand why genetic C1q and C1r/C1s deficiencies cause systemic lupus erythematosus. PMID:26231209

  6. C1q protein binds to the apoptotic nucleolus and causes C1 protease degradation of nucleolar proteins.

    PubMed

    Cai, Yitian; Teo, Boon Heng Dennis; Yeo, Joo Guan; Lu, Jinhua

    2015-09-11

    In infection, complement C1q recognizes pathogen-congregated antibodies and elicits complement activation. Among endogenous ligands, C1q binds to DNA and apoptotic cells, but whether C1q binds to nuclear DNA in apoptotic cells remains to be investigated. With UV irradiation-induced apoptosis, C1q initially bound to peripheral cellular regions in early apoptotic cells. By 6 h, binding concentrated in the nuclei to the nucleolus but not the chromatins. When nucleoli were isolated from non-apoptotic cells, C1q also bound to these structures. In vivo, C1q exists as the C1 complex (C1qC1r2C1s2), and C1q binding to ligands activates the C1r/C1s proteases. Incubation of nucleoli with C1 caused degradation of the nucleolar proteins nucleolin and nucleophosmin 1. This was inhibited by the C1 inhibitor. The nucleoli are abundant with autoantigens. C1q binding and C1r/C1s degradation of nucleolar antigens during cell apoptosis potentially reduces autoimmunity. These findings help us to understand why genetic C1q and C1r/C1s deficiencies cause systemic lupus erythematosus. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  7. Mass tracking and material accounting in the Integral Fast Reactor (IFR)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Orechwa, Y.; Adams, C.H.; White, A.M.

    1991-01-01

    The Integral Fast Reactor (IFR) is a generic advanced liquid metal cooled reactor concept being developed at Argonne National Laboratory (ANL). There are a number of technical features of the IFR which contribute to its potential as a next-generation reactor. These are associated with large safety margins with regard to off-normal events involving the heat transport system, and the use of metallic fuel which makes possible the utilization of innovative fuel cycle processes. The latter feature permits fuel cycle closure the compact, low-cost reprocessing facilities, collocated with the reactor plant. These primary features are being demonstrated in the facilities atmore » ANL-West, utilizing Experimental Breeder Reactor 2 and the associated Fuel Cycle Facility (FCF) as an IFR prototype. The demonstration of this IFR prototype includes the design and implementation of the Mass-Tracking System (MTG). In this system, data from the operations of the FCF, including weights and batch-process parameters, are collected and maintained by the MTG running on distributed workstations. The components of the MTG System include: (1) an Oracle database manager with a Fortran interface, (2) a set of MTG Tasks'' which collect, manipulate and report data, (3) a set of MTG Terminal Sessions'' which provide some interactive control of the Tasks, and (4) a set of servers which manage the Tasks and which provide the communications link between the MTG System and Operator Control Stations, which control process equipment and monitoring devices within the FCF.« less

  8. A Language Translator for a Computer Aided Rapid Prototyping System.

    DTIC Science & Technology

    1988-03-01

    PROBLEM ................... S B. THE TRADITIONAL "WATERFALL LIFE CYCLE" .. ............... 14 C. RAPID PROTOTYPING...feature of everyday life for almost the entire industrialized world. Few governments or businesses function without the aid of computer systems. Com...engineering. B. TIE TRADITIONAL "WATERFALL LIFE CYCLE" I. Characteristics The traditional method of software engineering is the "waterfall life cycle

  9. 10 CFR 72.128 - Criteria for spent fuel, high-level radioactive waste, reactor-related greater than Class C waste...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., reactor-related greater than Class C waste, and other radioactive waste storage and handling. 72.128... STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Design Criteria § 72.128 Criteria for spent fuel, high-level radioactive waste, reactor...

  10. 10 CFR 72.128 - Criteria for spent fuel, high-level radioactive waste, reactor-related greater than Class C waste...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., reactor-related greater than Class C waste, and other radioactive waste storage and handling. 72.128... STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Design Criteria § 72.128 Criteria for spent fuel, high-level radioactive waste, reactor...

  11. Revised Atomistic Models of the Crystal Structure of C-S-H with high C/S Ratio

    NASA Astrophysics Data System (ADS)

    Kovačević, Goran; Nicoleau, Luc; Nonat, André; Veryazov, Valera

    2016-09-01

    The atomic structure of calcium-silicate-hydrate (C1.67-S-Hx) has been studied. Atomistic C-S-H models suggested in our previous study have been revised in order to perform a direct comparison of energetic stability of the different structures. An extensive set of periodic structures of C-S-H with variation of water content was created, and then optimized using molecular dynamics with reactive force field ReaxFF and quantum chemical semiempirical method PM6. All models show organization of water molecules inside the structure of C-S-H. The new geometries of C-S-H, reported in this paper, show lower relative energy with respect to the geometries from the original definition of C-S-H models. Model that corresponds to calcium enriched tobermorite structure has the lowest relative energy and the density closest to the experimental values.

  12. Observation of e + e → Φ χ c 1 and Φ χ c 2 at s = 4.600 GeV

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ablikim, M.; Achasov, M. N.; Ahmed, S.

    Using a data sample collected with the BESIII detector operating at the BEPCII storage ring at a centerof- mass energy of √s = 4.600 GeV, we search for the production of e +e - → φχ c0,1,2. A search is also performed for the charmonium-like state X(4140) in the radiative transition e +e - → γX(4140) with X(4140) subsequently decaying into φJ/ψ. The processes e +e - → φχ c1 and φχ c2 are observed for the first time, each with a statistical significance ofmore than 10σ, and the Born cross sections are measuredmore » to be (4.2+1.7 -1.0±0.3) pb and (6.7+3.4 -1.7 ± 0.5) pb, respectively, where the first uncertainties are statistical and the second systematic. No significant signals are observed for e +e - → φχ c0 and e +e - → γX(4140) and upper limits on the Born cross sections at 90% confidence level are provided at √s = 4.600 GeV.« less

  13. Observation of e + e → Φ χ c 1 and Φ χ c 2 at s = 4.600 GeV

    DOE PAGES

    Ablikim, M.; Achasov, M. N.; Ahmed, S.; ...

    2018-02-12

    Using a data sample collected with the BESIII detector operating at the BEPCII storage ring at a centerof- mass energy of √s = 4.600 GeV, we search for the production of e +e - → φχ c0,1,2. A search is also performed for the charmonium-like state X(4140) in the radiative transition e +e - → γX(4140) with X(4140) subsequently decaying into φJ/ψ. The processes e +e - → φχ c1 and φχ c2 are observed for the first time, each with a statistical significance ofmore than 10σ, and the Born cross sections are measuredmore » to be (4.2+1.7 -1.0±0.3) pb and (6.7+3.4 -1.7 ± 0.5) pb, respectively, where the first uncertainties are statistical and the second systematic. No significant signals are observed for e +e - → φχ c0 and e +e - → γX(4140) and upper limits on the Born cross sections at 90% confidence level are provided at √s = 4.600 GeV.« less

  14. Wide-range structurally optimized channel for monitoring the certified power of small-core reactors

    NASA Astrophysics Data System (ADS)

    Koshelev, A. S.; Kovshov, K. N.; Ovchinnikov, M. A.; Pikulina, G. N.; Sokolov, A. B.

    2016-12-01

    The results of tests of a prototype version of a channel for monitoring the certified power of small-core reactors performed at the BR-K1 reactor at the All-Russian Scientific Research Institute of Experimental Physics are reported. An SNM-11 counter and commercial KNK-4 and KNK-3 compensated ion chambers were used as neutron detectors in the tested channel, and certified NCMM and CCMM measurement modules controlled by a PC with specialized software were used as measuring instruments. The specifics of metrological assurance of calibration of the channel in the framework of reactor power monitoring are discussed.

  15. Wide-range structurally optimized channel for monitoring the certified power of small-core reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koshelev, A. S., E-mail: alexsander.coshelev@yandex.ru; Kovshov, K. N.; Ovchinnikov, M. A.

    The results of tests of a prototype version of a channel for monitoring the certified power of small-core reactors performed at the BR-K1 reactor at the All-Russian Scientific Research Institute of Experimental Physics are reported. An SNM-11 counter and commercial KNK-4 and KNK-3 compensated ion chambers were used as neutron detectors in the tested channel, and certified NCMM and CCMM measurement modules controlled by a PC with specialized software were used as measuring instruments. The specifics of metrological assurance of calibration of the channel in the framework of reactor power monitoring are discussed.

  16. MQ-1C Gray Eagle Unmanned Aircraft System (MQ-1C Gray Eagle)

    DTIC Science & Technology

    2015-12-01

    Selected Acquisition Report ( SAR ) RCS: DD-A&T(Q&A)823-420 MQ-1C Gray Eagle Unmanned Aircraft System (MQ-1C Gray Eagle) As of FY 2017 President’s...Budget Defense Acquisition Management Information Retrieval (DAMIR) March 21, 2016 17:33:19 UNCLASSIFIED MQ-1C Gray Eagle December 2015 SAR March 21...Gray Eagle December 2015 SAR March 21, 2016 17:33:19 UNCLASSIFIED 3 PB - President’s Budget PE - Program Element PEO - Program Executive Officer PM

  17. A Circadian Rhythm in both Complement Cascade (ComC) Activation and Sphingosine-1-Phosphate (S1P) Levels in Human Peripheral Blood Supports a Role for the ComC-S1P Axis in Circadian Changes in the Number of Stem Cells Circulating in Peripheral Blood.

    PubMed

    Budkowska, Marta; Ostrycharz, Ewa; Wojtowicz, Adrianna; Marcinowska, Zuzanna; Woźniak, Jarosław; Ratajczak, Mariusz Z; Dołęgowska, Barbara

    2018-06-17

    The number of hematopoietic stem/progenitor cells (HSPCs) circulating in peripheral blood (PB) is regulated by a circadian rhythm, and more HSPCs circulate in PB in the morning hours than at night. Different mechanisms have been proposed that might regulate this process, including changes in tonus of β-adrenergic innervation of bone marrow (BM) tissue. Our group reported that in mice circadian changes in the number of HSPCs circulating in PB correlates with diurnal activation of the complement cascade (ComC) and that the mice deficient in C5 component of ComC (C5-KO mice) do not show circadian changes in the number of circulating HSPCs in PB. We also reported the existence of a gradient between PB and BM of a bioactive phosphosphingolipid, sphingosine-1-phosphate (S1P), which is a major PB chemottractant for BM-residing HSPCs. Based on these observations, we investigated activation of the ComC and the level of S1P in the PB of 66 healthy volunteers. We found that both ComC activation and the S1P level undergo changes in a circadian cycle. While the ComC becomes highly activated during deep sleep at 2 am, S1P becomes activated later, and its highest level is observed at 8 am, which precedes circadian egress of HSPCs from BM into PB. In sum, circadian activation of the ComC-S1P axis releases HSPCs from BM into PB.

  18. Kinetics of the R + NO2 reactions (R = i-C3H7, n-C3H7, s-C4H9, and t-C4H9) in the temperature range 201-489 K.

    PubMed

    Rissanen, Matti P; Arppe, Suula L; Eskola, Arkke J; Tammi, Matti M; Timonen, Raimo S

    2010-04-15

    The bimolecular rate coefficients of four alkyl radical reactions with NO(2) have been measured in direct time-resolved experiments. Reactions were studied under pseudo-first-order conditions in a temperature-controlled tubular flow reactor coupled to a laser photolysis/photoionization mass spectrometer (LP-PIMS). The measured reaction rate coefficients are independent of helium bath gas pressure within the experimental ranges covered and exhibit negative temperature dependence. For i-C(3)H(7) + NO(2) and t-C(4)H(9) + NO(2) reactions, the dependence of ordinate (logarithm of reaction rate coefficients) on abscissa (1/T or log(T)) was nonlinear. The obtained results (in cm(3) s(-1)) can be expressed by the following equations: k(n-C(3)H(7) + NO(2)) = ((4.34 +/- 0.08) x 10(-11)) (T/300 K)(-0.14+/-0.08) (203-473 K, 1-7 Torr), k(i-C(3)H(7) + NO(2)) = ((3.66 +/- 2.54) x 10(-12)) exp(656 +/- 201 K/T)(T/300 K)(1.26+/-0.68) (220-489 K, 1-11 Torr), k(s-C(4)H(9) + NO(2)) = ((4.99 +/- 0.16) x 10(-11))(T/300 K)(-1.74+/-0.12) (241-485 K, 2 - 12 Torr) and k(t-C(4)H(9) + NO(2)) = ((8.64 +/- 4.61) x 10(-12)) exp(413 +/- 154 K/T)(T/300 K)(0.51+/-0.55) (201-480 K, 2-11 Torr), where the uncertainties shown refer only to the 1 standard deviations obtained from the fitting procedure. The estimated overall uncertainty in the determined bimolecular rate coefficients is about +/-20%.

  19. Prototyping Control and Data Acquisition for the ITER Neutral Beam Test Facility

    NASA Astrophysics Data System (ADS)

    Luchetta, Adriano; Manduchi, Gabriele; Taliercio, Cesare; Soppelsa, Anton; Paolucci, Francesco; Sartori, Filippo; Barbato, Paolo; Breda, Mauro; Capobianco, Roberto; Molon, Federico; Moressa, Modesto; Polato, Sandro; Simionato, Paola; Zampiva, Enrico

    2013-10-01

    The ITER Neutral Beam Test Facility will be the project's R&D facility for heating neutral beam injectors (HNB) for fusion research operating with H/D negative ions. Its mission is to develop technology to build the HNB prototype injector meeting the stringent HNB requirements (16.5 MW injection power, -1 MeV acceleration energy, 40 A ion current and one hour continuous operation). Two test-beds will be built in sequence in the facility: first SPIDER, the ion source test-bed, to optimize the negative ion source performance, second MITICA, the actual prototype injector, to optimize ion beam acceleration and neutralization. The SPIDER control and data acquisition system is under design. To validate the main architectural choices, a system prototype has been assembled and performance tests have been executed to assess the prototype's capability to meet the control and data acquisition system requirements. The prototype is based on open-source software frameworks running under Linux. EPICS is the slow control engine, MDSplus is the data handler and MARTe is the fast control manager. The prototype addresses low and high-frequency data acquisition, 10 kS/s and 10 MS/s respectively, camera image acquisition, data archiving, data streaming, data retrieval and visualization, real time fast control with 100 μs control cycle and supervisory control.

  20. Health Physics State of the RA-1 Reactor, Period Between 1-1-62 and 10-8- 62. Report No. 87; ESTADO RADIOSANIT ARIO DEL REACTOR R.A. 1, PERIODO COMPRENDIDO ENTRE EL 1-1-62 Y EL 10-8-62. Informe No. 87

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gaspar, R.; Moll, O.; Hermelo, C.

    1963-01-01

    The methods used to measure the irradiation levels and the radiation exposure of personnel of the RA-1 reactor are described. The criteria used to evaluate the risks from this exposure are reported. Typical graphs are shown of the radiation levels measured in the control room. (J.S.R.)

  1. Mass spectra for q c q ¯ c ¯, s c s ¯ c ¯, q b q ¯ ¯, s b s ¯ ¯ tetraquark states with JP C=0++ and 2++

    NASA Astrophysics Data System (ADS)

    Chen, Wei; Chen, Hua-Xing; Liu, Xiang; Steele, T. G.; Zhu, Shi-Lin

    2017-12-01

    We have studied the mass spectra of the hidden-charm/bottom q c q ¯c ¯, s c s ¯c ¯ and q b q ¯b ¯, s b s ¯b ¯ tetraquark states with JP C=0++ and 2++ in the framework of QCD sum rules. We construct ten scalar and four tensor interpolating currents in a systematic way and calculate the mass spectra for these tetraquark states. The X*(3860 ) may be either an isoscalar tetraquark state or χc 0(2 P ). If the X*(3860 ) is a tetraquark candidate, our results prefer the 0++ option over the 2++ one. The X (4160 ) may be classified as either the scalar or tensor q c q ¯c ¯ tetraquark state, while the X (3915 ) favors a 0++ q c q ¯c ¯ or s c s ¯c ¯ tetraquark assignment over the tensor one. The X (4350 ) cannot be interpreted as a s c s ¯c ¯ tetraquark with either JP C=0++ or 2++.

  2. Mass tracking and material accounting in the integral fast reactor (IFR)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Orechwa, Y.; Adams, C.H.; White, A.M.

    1991-01-01

    This paper reports on the Integral Fast Reactor (IFR) which is a generic advanced liquid metal cooled reactor concept being developed at Argonne National Laboratory. There are a number of technical features of the IFR which contribute to its potential as a next-generation reactor. These are associated with large safety margins with regard to off-normal events involving the heat transport system, and the use of metallic fuel which makes possible the utilization of innovative fuel cycle processes. The latter feature permits fuel cycle closure with compact, low-cost reprocessing facilities, collocated with the reactor plant. These primary features are being demonstratedmore » in the facilities at ANL-West, utilizing Experimental Breeder Reactor II and the associated Fuel Cycle Facility (FCF) as an IFR prototype. The demonstration of this IFR prototype includes the design and implementation of the Mass-tracking System (MTG). In this system, data from the operations of the FCF, including weights and batch-process parameters, are collected and maintained by the MTG running on distributed workstations.« less

  3. Observation of e+e-→ϕ χc 1 and ϕ χc 2 at √{s }=4.600 GeV

    NASA Astrophysics Data System (ADS)

    Ablikim, M.; Achasov, M. N.; Ahmed, S.; Albrecht, M.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Bai, Y.; Bakina, O.; Baldini Ferroli, R.; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Berger, N.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chai, J.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, J. C.; Chen, M. L.; Chen, P. L.; Chen, S. J.; Chen, X. R.; Chen, Y. B.; Chu, X. K.; Cibinetto, G.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; de Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Dou, Z. L.; Du, S. X.; Duan, P. F.; Fang, J.; Fang, S. S.; Fang, Y.; Farinelli, R.; Fava, L.; Fegan, S.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. L.; Gao, Y.; Gao, Y. G.; Gao, Z.; Garzia, I.; Goetzen, K.; Gong, L.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guo, A. Q.; Guo, R. P.; Guo, Y. P.; Haddadi, Z.; Han, S.; Hao, X. Q.; Harris, F. A.; He, K. L.; He, X. Q.; Heinsius, F. H.; Held, T.; Heng, Y. K.; Holtmann, T.; Hou, Z. L.; Hu, H. M.; Hu, T.; Hu, Y.; Huang, G. S.; Huang, J. S.; Huang, X. T.; Huang, X. Z.; Huang, Z. L.; Hussain, T.; Ikegami Andersson, W.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, X. S.; Jiang, X. Y.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Jin, Y.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Khan, T.; Khoukaz, A.; Kiese, P.; Kliemt, R.; Koch, L.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kuemmel, M.; Kuessner, M.; Kuhlmann, M.; Kupsc, A.; Kühn, W.; Lange, J. S.; Lara, M.; Larin, P.; Lavezzi, L.; Leithoff, H.; Leng, C.; Li, C.; Li, Cheng; Li, D. M.; Li, F.; Li, F. Y.; Li, G.; Li, H. B.; Li, H. J.; Li, J. C.; Li, Jin; Li, K. J.; Li, Kang; Li, Ke; Li, Lei; Li, P. L.; Li, P. R.; Li, Q. Y.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B.; Liu, B. J.; Liu, C. X.; Liu, D.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. M.; Liu, Huanhuan; Liu, Huihui; Liu, J. B.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, Ke; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqing; Long, Y. F.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, X. L.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, M. M.; Ma, Q. M.; Ma, T.; Ma, X. N.; Ma, X. Y.; Ma, Y. M.; Maas, F. E.; Maggiora, M.; Malik, Q. A.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Meng, Z. X.; Messchendorp, J. G.; Mezzadri, G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales Morales, C.; Muchnoi, N. Yu.; Muramatsu, H.; Musiol, P.; Mustafa, A.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pan, Y.; Papenbrock, M.; Patteri, P.; Pelizaeus, M.; Pellegrino, J.; Peng, H. P.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Pitka, A.; Poling, R.; Prasad, V.; Qi, H. R.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, N.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Richter, M.; Ripka, M.; Rolo, M.; Rong, G.; Rosner, Ch.; Sarantsev, A.; Savrié, M.; Schnier, C.; Schoenning, K.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Song, J. J.; Song, W. M.; Song, X. Y.; Sosio, S.; Sowa, C.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, L.; Sun, S. S.; Sun, X. H.; Sun, Y. J.; Sun, Y. K.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, G. Y.; Tang, X.; Tapan, I.; Tiemens, M.; Tsednee, B.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, D.; Wang, D. Y.; Wang, Dan; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, Meng; Wang, P.; Wang, P. L.; Wang, W. P.; Wang, X. F.; Wang, Y.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. Y.; Wang, Zongyuan; Weber, T.; Wei, D. H.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, L. J.; Wu, Z.; Xia, L.; Xia, Y.; Xiao, D.; Xiao, H.; Xiao, Y. J.; Xiao, Z. J.; Xie, Y. G.; Xie, Y. H.; Xiong, X. A.; Xiu, Q. L.; Xu, G. F.; Xu, J. J.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. J.; Yang, H. X.; Yang, L.; Yang, Y. H.; Yang, Y. X.; Ye, M.; Ye, M. H.; Yin, J. H.; You, Z. Y.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zeng, Y.; Zeng, Z.; Zhang, B. X.; Zhang, B. Y.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, S. Q.; Zhang, X. Y.; Zhang, Y. H.; Zhang, Y. T.; Zhang, Yang; Zhang, Yao; Zhang, Yu; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhou, Y. X.; Zhu, J.; Zhu, J.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, S. H.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zou, B. S.; Zou, J. H.; Besiii Collaboration

    2018-02-01

    Using a data sample collected with the BESIII detector operating at the BEPCII storage ring at a center-of-mass energy of √{s }=4.600 GeV , we search for the production of e+e-→ϕ χc 0 ,1 ,2 . A search is also performed for the charmonium-like state X (4140 ) in the radiative transition e+e-→γ X (4140 ) with X (4140 ) subsequently decaying into ϕ J /ψ . The processes e+e-→ϕ χc 1 and ϕ χc 2 are observed for the first time, each with a statistical significance of more than 10 σ , and the Born cross sections are measured to be (4. 2-1.0+1.7±0.3 ) and (6. 7-1.7+3.4±0.5 ) pb , respectively, where the first uncertainties are statistical and the second systematic. No significant signals are observed for e+e-→ϕ χc 0 and e+e-→γ X (4140 ) and upper limits on the Born cross sections at 90% C.L. are provided at √{s }=4.600 GeV .

  4. Design of the AFGL Prototype Long Baseline Tiltmeter.

    DTIC Science & Technology

    1985-08-29

    331 row Design of the AFGL Prototype Long Baseline Tiltmeter Ik KENNETH 0. POHLIG, ILt, USAF SCHARINE KIRCHOFF ~ 29 August 1985 ilL Approved for... Tiltmeter 9ATRT,rI,f,’, Kent 0. ,se." 11A de’. I, , andIl ,,,,’.cho, Shr seso eliltrCoic s andEC ineEae and -1- res th oue cssema isd inlded. Reslt ofoc...aubr twoda ts arer described. theeina prototyp elnba lie tiltmetershows ah hdpedneupns temper~ature variation. Trhis must be eliminated if the tiltmeter

  5. Lattice potential energy and standard molar enthalpy in the formation of 1—dodecylamine hydrobromide (1-C12H25NH3·Br)(s)

    NASA Astrophysics Data System (ADS)

    Liu, Yu-Pu; Di, You-Ying; Dan, Wen-Yan; He, Dong-Hua; Kong, Yu-Xia; Yang, Wei-Wei

    2011-02-01

    This paper reports that 1-dodecylamine hydrobromide (1-C12H25NH3·Br)(s) has been synthesized using the liquid phase reaction method. The lattice potential energy of the compound 1-C12H25NH3·Br and the ionic volume and radius of the 1-C12H25NH3+ cation are obtained from the crystallographic data and other auxiliary thermodynamic data. The constant-volume energy of combustion of 1-C12H25NH3·Br(s) is measured to be ΔcUmo(1-C12H25NH3·Br, s) = -(7369.03±3.28) kJ·mol-1 by means of an RBC-II precision rotating-bomb combustion calorimeter at T = (298.15±0.001) K. The standard molar enthalpy of combustion of the compound is derived to be ΔcHmo(1-C12H25NH3·Br, s) = -(7384.52±3.28) kJ·mol-1 from the constant-volume energy of combustion. The standard molar enthalpy of formation of the compound is calculated to be ΔfHmo(1-C12H25NH3·Br, s)=-(1317.86±3.67) kJ·mol-1 from the standard molar enthalpy of combustion of the title compound and other auxiliary thermodynamic quantities through a thermochemical cycle.

  6. Prototype diagnosis of psychiatric syndromes

    PubMed Central

    WESTEN, DREW

    2012-01-01

    The method of diagnosing patients used since the early 1980s in psychiatry, which involves evaluating each of several hundred symptoms for their presence or absence and then applying idiosyncratic rules for combining them for each of several hundred disorders, has led to great advances in research over the last 30 years. However, its problems have become increasingly apparent, particularly for clinical practice. An alternative approach, designed to maximize clinical utility, is prototype matching. Instead of counting symptoms of a disorder and determining whether they cross an arbitrary cutoff, the task of the diagnostician is to gauge the extent to which a patient’s clinical presentation matches a paragraph-length description of the disorder using a simple 5-point scale, from 1 (“little or no match”) to 5 (“very good match”). The result is both a dimensional diagnosis that captures the extent to which the patient “has” the disorder and a categorical diagnosis, with ratings of 4 and 5 corresponding to presence of the disorder and a rating of 3 indicating “subthreshold” or “clinically significant features”. The disorders and criteria woven into the prototypes can be identified empirically, so that the prototypes are both scientifically grounded and clinically useful. Prototype diagnosis has a number of advantages: it better captures the way humans naturally classify novel and complex stimuli; is clinically helpful, reliable, and easy to use in everyday practice; facilitates both dimensional and categorical diagnosis and dramatically reduces the number of categories required for classification; allows for clinically richer, empirically derived, and culturally relevant classification; reduces the gap between research criteria and clinical knowledge, by allowing clinicians in training to learn a small set of standardized prototypes and to develop richer mental representations of the disorders over time through clinical experience; and can help

  7. FRACTURE STRENGTH AND TIME DEPENDENT PROPERTIES OF 0/90 AND ±55-BRAIDED WEAVE SiC/SiC TYPE-S FIBER COMPOSITES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Henager, Charles H.

    PNNL has performed mechanical property tests on two types of Hi-Nicalon Type-S fiber SiC/SiC composites for the general purpose of evaluating such composites for control rod guide tube applications in the NGNP high-temperature gas-cooled reactor design. The mechanical testing consisted of 4-point bend strength, 4-point single-edge notched bend fracture toughness, and 4-point bend slow crack growth testing on both composites from ambient to 1600°C (1873K). The two composite materials that were tested included a ±55°-braided-weave composite with Type-S fibers inclined at 55° to the principal composite axes to simulate a braided tube architecture and a Type-S 0/90 satin-weave composite asmore » a reference material.« less

  8. Anomalous 13C isotope abundances in C3S and C4H observed toward the cold interstellar cloud, Taurus Molecular Cloud-1.

    PubMed

    Sakai, Nami; Takano, Shuro; Sakai, Takeshi; Shiba, Shoichi; Sumiyoshi, Yoshihiro; Endo, Yasuki; Yamamoto, Satoshi

    2013-10-03

    We have studied the abundances of the (13)C isotopic species of C3S and C4H in the cold molecular cloud, Taurus Molecular Cloud-1 (Cyanopolyyne Peak), by radioastronomical observations of their rotational emission lines. The CCCS/(13)CCCS and CCCS/C(13)CCS ratios are determined to be >206 and 48 ± 15, respectively. The CC(13)CS line is identified with the aid of laboratory microwave spectroscopy, and the range of the CCCS/CC(13)CS ratio is found to be from 30 to 206. The abundances of at least two (13)C isotopic species of C3S are thus found to be different. Similarly, it is found that the abundances of the four (13)C isotopic species of C4H are not equivalent. The CCCCH/(13)CCCCH, CCCCH/C(13)CCCH, CCCCH/CC(13)CCH, and CCCCH/CCC(13)CH ratios are evaluated to be 141 ± 44, 97 ± 27, 82 ± 15, and 118 ± 23, respectively. Here the errors denote 3 times the standard deviation. These results will constrain the formation pathways of C3S and C4H, if the nonequivalence is caused during the formation processes of these molecules. The exchange reactions after the formation of these two molecules may also contribute to the nonequivalence. In addition, we have confirmed that the (12)C/(13)C ratio of some species are significantly higher than the interstellar elemental (12)C/(13)C ratio of 60-70. The observations of the (13)C isotopic species provide us with rich information on chemical processes in cold interstellar clouds.

  9. Successive and large-scale synthesis of InP/ZnS quantum dots in a hybrid reactor and their application to white LEDs

    NASA Astrophysics Data System (ADS)

    Kim, Kyungnam; Jeong, Sohee; Woo, Ju Yeon; Han, Chang-Soo

    2012-02-01

    We report successive and large-scale synthesis of InP/ZnS core/shell nanocrystal quantum dots (QDs) using a customized hybrid flow reactor, which is based on serial combination of a batch-type mixer and a flow-type furnace. InP cores and InP/ZnS core/shell QDs were successively synthesized in the hybrid reactor in a simple one-step process. In this reactor, the flow rate of the solutions was typically 1 ml min-1, 100 times larger than that of conventional microfluidic reactors. In order to synthesize high-quality InP/ZnS QDs, we controlled both the flow rate and the crystal growth temperature. Finally, we obtained high-quality InP/ZnS QDs in colors from bluish green to red, and we demonstrated that these core/shell QDs could be incorporated into white-light-emitting diode (LED) devices to improve color rendering performance.

  10. Successive and large-scale synthesis of InP/ZnS quantum dots in a hybrid reactor and their application to white LEDs.

    PubMed

    Kim, Kyungnam; Jeong, Sohee; Woo, Ju Yeon; Han, Chang-Soo

    2012-02-17

    We report successive and large-scale synthesis of InP/ZnS core/shell nanocrystal quantum dots (QDs) using a customized hybrid flow reactor, which is based on serial combination of a batch-type mixer and a flow-type furnace. InP cores and InP/ZnS core/shell QDs were successively synthesized in the hybrid reactor in a simple one-step process. In this reactor, the flow rate of the solutions was typically 1 ml min(-1), 100 times larger than that of conventional microfluidic reactors. In order to synthesize high-quality InP/ZnS QDs, we controlled both the flow rate and the crystal growth temperature. Finally, we obtained high-quality InP/ZnS QDs in colors from bluish green to red, and we demonstrated that these core/shell QDs could be incorporated into white-light-emitting diode (LED) devices to improve color rendering performance.

  11. Development of a Prototype Algal Reactor for Removing CO2 from Cabin Air

    NASA Technical Reports Server (NTRS)

    Patel, Vrajen; Monje, Oscar

    2013-01-01

    Controlling carbon dioxide in spacecraft cabin air may be accomplished using algal photobioreactors (PBRs). The purpose of this project was to evaluate the use of a commercial microcontroller, the Arduino Mega 2560, for measuring key photioreactor variables: dissolved oxygen, pH, temperature, light, and carbon dioxide. The Arduino platform is an opensource physical computing platform composed of a compact microcontroller board and a C++/C computer language (Arduino 1.0.5). The functionality of the Arduino platform can be expanded by the use of numerous add-ons or 'shields'. The Arduino Mega 2560 was equipped with the following shields: datalogger, BNC shield for reading pH sensor, a Mega Moto shield for controlling CO2 addition, as well as multiple sensors. The dissolved oxygen (DO) probe was calibrated using a nitrogen bubbling technique and the pH probe was calibrated via an Omega pH simulator. The PBR was constructed using a 2 L beaker, a 66 L box for addition of CO2, a micro porous membrane, a diaphragm pump, four 25 watt light bulbs, a MasterFiex speed controller, and a fan. The algae (wild type Synechocystis PCC6803) was grown in an aerated flask until the algae was dense enough to used in the main reactor. After the algae was grown, it was transferred to the 2 L beaker where CO2 consumption and O2 production was measured using the microcontroller sensor suite. The data was recorded via the datalogger and transferred to a computer for analysis.

  12. Nucleotide sequences of bovine alpha S1- and kappa-casein cDNAs.

    PubMed Central

    Stewart, A F; Willis, I M; Mackinlay, A G

    1984-01-01

    The nucleotide sequences corresponding to bovine alpha S1- and kappa-casein mRNAs are presented. An unusual alpha S1-casein cDNA has been characterised whose 5' end commences upstream from its putative TATA box. The alpha S1-casein mRNA is compared to rat alpha-casein mRNA and two components of divergence are identified. Firstly, the two sequences have diverged at a high point mutation rate and the rate of amino acid replacement by this mechanism is at least as great as the rate of divergence of any other part of the mRNAs. Secondly, the protein coding sequence has been subjected to several insertion/deletion events, one of which may be an example of exon shuffling . The kappa-casein mRNA sequence verifies the proposition that it has arisen from a different ancestral gene to the other caseins. Images PMID:6328443

  13. Design and Delivery of HMT Half-Shaft Prototype

    DTIC Science & Technology

    2012-11-01

    spindle welded to the outer joint output is ease of Design  and Delivery of HMT Half‐ Shaft  Prototype    24    assembly. Flange 1 contains threaded... spindle , and splined shafts . Also, the spindle of the production design is splined to match the splines of the hub internals. 2.2. Analysis The...inner-joint (Figure 33). Design  and Delivery of HMT Half‐ Shaft  Prototype    27      Figure 33: FBD of Flange/ Spindle Applying Newton’s Laws to the

  14. Experiment for search for sterile neutrino at SM-3 reactor

    NASA Astrophysics Data System (ADS)

    Serebrov, A. P.; Ivochkin, V. G.; Samoylov, R. M.; Fomin, A. K.; Zinoviev, V. G.; Neustroev, P. V.; Golovtsov, V. L.; Gruzinsky, N. V.; Solovey, V. A.; Cherniy, A. V.; Zherebtsov, O. M.; Martemyanov, V. P.; Zinoev, V. G.; Tarasenkov, V. G.; Aleshin, V. I.; Petelin, A. L.; Pavlov, S. V.; Izhutov, A. L.; Sazontov, S. A.; Ryazanov, D. K.; Gromov, M. O.; Afanasiev, V. V.; Matrosov, L. N.; Matrosova, M. Yu.

    2016-11-01

    In connection with the question of possible existence of sterile neutrino the laboratory on the basis of SM-3 reactor was created to search for oscillations of reactor antineutrino. A prototype of a neutrino detector with scintillator volume of 400 l can be moved at the distance of 6-11 m from the reactor core. The measurements of background conditions have been made. It is shown that the main experimental problem is associated with cosmic radiation background. Test measurements of dependence of a reactor antineutrino flux on the distance from a reactor core have been made. The prospects of search for oscillations of reactor antineutrino at short distances are discussed.

  15. Junctional Adhesion Molecule A Serves as a Receptor for Prototype and Field-Isolate Strains of Mammalian Reovirus

    PubMed Central

    Campbell, Jacquelyn A.; Schelling, Pierre; Wetzel, J. Denise; Johnson, Elizabeth M.; Forrest, J. Craig; Wilson, Greame A. R.; Aurrand-Lions, Michel; Imhof, Beat A.; Stehle, Thilo; Dermody, Terence S.

    2005-01-01

    Reovirus infections are initiated by the binding of viral attachment protein σ1 to receptors on the surface of host cells. The σ1 protein is an elongated fiber comprised of an N-terminal tail that inserts into the virion and a C-terminal head that extends from the virion surface. The prototype reovirus strains type 1 Lang/53 (T1L/53) and type 3 Dearing/55 (T3D/55) use junctional adhesion molecule A (JAM-A) as a receptor. The C-terminal half of the T3D/55 σ1 protein interacts directly with JAM-A, but the determinants of receptor-binding specificity have not been identified. In this study, we investigated whether JAM-A also mediates the attachment of the prototype reovirus strain type 2 Jones/55 (T2J/55) and a panel of field-isolate strains representing each of the three serotypes. Antibodies specific for JAM-A were capable of inhibiting infections of HeLa cells by T1L/53, T2J/55, and T3D/55, demonstrating that strains of all three serotypes use JAM-A as a receptor. To corroborate these findings, we introduced JAM-A or the structurally related JAM family members JAM-B and JAM-C into Chinese hamster ovary cells, which are poorly permissive for reovirus infection. Both prototype and field-isolate reovirus strains were capable of infecting cells transfected with JAM-A but not those transfected with JAM-B or JAM-C. A sequence analysis of the σ1-encoding S1 gene segment of the strains chosen for study revealed little conservation in the deduced σ1 amino acid sequences among the three serotypes. This contrasts markedly with the observed sequence variability within each serotype, which is confined to a small number of amino acids. Mapping of these residues onto the crystal structure of σ1 identified regions of conservation and variability, suggesting a likely mode of JAM-A binding via a conserved surface at the base of the σ1 head domain. PMID:15956543

  16. 11 CFR 111.4 - Complaints (2 U.S.C. 437g(a)(1)).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 11 Federal Elections 1 2012-01-01 2012-01-01 false Complaints (2 U.S.C. 437g(a)(1)). 111.4 Section... knowledge and statements based upon information and belief. (d) The complaint should conform to the... accompanied by an identification of the source of information which gives rise to the complainants belief in...

  17. 11 CFR 111.4 - Complaints (2 U.S.C. 437g(a)(1)).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Complaints (2 U.S.C. 437g(a)(1)). 111.4 Section... knowledge and statements based upon information and belief. (d) The complaint should conform to the... accompanied by an identification of the source of information which gives rise to the complainants belief in...

  18. 11 CFR 111.4 - Complaints (2 U.S.C. 437g(a)(1)).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 11 Federal Elections 1 2011-01-01 2011-01-01 false Complaints (2 U.S.C. 437g(a)(1)). 111.4 Section... knowledge and statements based upon information and belief. (d) The complaint should conform to the... accompanied by an identification of the source of information which gives rise to the complainants belief in...

  19. 11 CFR 111.4 - Complaints (2 U.S.C. 437g(a)(1)).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 11 Federal Elections 1 2014-01-01 2014-01-01 false Complaints (2 U.S.C. 437g(a)(1)). 111.4 Section... knowledge and statements based upon information and belief. (d) The complaint should conform to the... accompanied by an identification of the source of information which gives rise to the complainants belief in...

  20. Support vector machines for nuclear reactor state estimation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zavaljevski, N.; Gross, K. C.

    2000-02-14

    Validation of nuclear power reactor signals is often performed by comparing signal prototypes with the actual reactor signals. The signal prototypes are often computed based on empirical data. The implementation of an estimation algorithm which can make predictions on limited data is an important issue. A new machine learning algorithm called support vector machines (SVMS) recently developed by Vladimir Vapnik and his coworkers enables a high level of generalization with finite high-dimensional data. The improved generalization in comparison with standard methods like neural networks is due mainly to the following characteristics of the method. The input data space is transformedmore » into a high-dimensional feature space using a kernel function, and the learning problem is formulated as a convex quadratic programming problem with a unique solution. In this paper the authors have applied the SVM method for data-based state estimation in nuclear power reactors. In particular, they implemented and tested kernels developed at Argonne National Laboratory for the Multivariate State Estimation Technique (MSET), a nonlinear, nonparametric estimation technique with a wide range of applications in nuclear reactors. The methodology has been applied to three data sets from experimental and commercial nuclear power reactor applications. The results are promising. The combination of MSET kernels with the SVM method has better noise reduction and generalization properties than the standard MSET algorithm.« less

  1. ARMY GAS-COOLED REACTOR SYSTEMS PROGRAM. Quarterly Progress Report, October 1-December 31, 1963

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1964-02-15

    The ML-1 power plant did not operate during the report period; low power reactor physics and shielding experiments were conducted with the ML-1 reactor. Evaluation of moderate corrosion observed on aluminum parts exposed to the ML-1 shield solution indicated no loss of performance capability. Preliminary tests showed that the corrosion probably was caused by heavy metal ions or chlorides in the solution, Massive corrosion observed on the ML-1 fuel element lower spiders was attributed to sub-standard material; failure of some spiders was attributed to a combination of corrosion and sub-standard fabrication. Evaluation indicated that the upper spiders will perform satisfactorilymore » for the design lifetime. Modification, repair, and reassembly of the CSN-1A t-c set was completed. Operation demonstrated bearing stability, but showed that the turbine effective flow area was too large. A bypass flow path in the turbine was being corrected. The TCS-670 t-c set will be stored indefinitely. Since a commercial alternator will be used for the ML-1A, further development of the brushless alternator was postponed indefinitely. Evaluation revealed that the ML-1 improved precooler design was not compatible with ML-1A requirements. Operntion of the IB-17R-2 and -3 test elements in the GETR continued without incident. Preliminary design of the ML-1A power plant was initiated. Design of modifications to the GCRE facility to adapt it to testing the ML-1 reactor skid was initiated. (auth)« less

  2. A failure management prototype: DR/Rx

    NASA Technical Reports Server (NTRS)

    Hammen, David G.; Baker, Carolyn G.; Kelly, Christine M.; Marsh, Christopher A.

    1991-01-01

    This failure management prototype performs failure diagnosis and recovery management of hierarchical, distributed systems. The prototype, which evolved from a series of previous prototypes following a spiral model for development, focuses on two functions: (1) the diagnostic reasoner (DR) performs integrated failure diagnosis in distributed systems; and (2) the recovery expert (Rx) develops plans to recover from the failure. Issues related to expert system prototype design and the previous history of this prototype are discussed. The architecture of the current prototype is described in terms of the knowledge representation and functionality of its components.

  3. C 1 s ionization in C sub 2 H sub 2 studied by asymmetric ( e ,2 e ) experiments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Avaldi, L.; Camilloni, R.; Stefani, G.

    1990-01-01

    The dynamics of core ionization by electron impact is investigated through the measurement of the triply differential cross section of the C {sigma}1{ital s} orbital in the molecule C{sub 2}H{sub 2}. The ({ital e},2{ital e}) experiments have been performed under asymmetric conditions and at small scattering angles, with a scattered electron energy of 1500 eV and low energies of the ejected electrons (9.6 and 41.0 eV). The measured angular distributions are characterized by large-size recoil lobes, breaking of the symmetry around the momentum-transfer direction, and unusual deviations of the maxima of the recoil peaks towards smaller deflection angles. In themore » ({ital e},2{ital e}) energy spectrum a shift is observed in the position of the C {sigma}1{ital s} peak with respect to the expected value as measured by x-ray photoelectron spectroscopy. The amplitude of the shift amounts to 0.46{plus minus}0.23 eV at 9.6 eV excess energy, and it is too large to be explained only in terms of postcollision interactions.« less

  4. Prototype Solid State Induction Modulator for SLAC NLC

    NASA Astrophysics Data System (ADS)

    Cassel, R. L.; DeLamare, J. E.; Nguyen, M. N.; Pappas, G. C.; Cook, E.

    2002-08-01

    The Next Linear Collider accelerator proposal at SLAC requires a high efficiency, highly reliable, and low cost pulsed power modulator to drive the X band klystrons. The present NLC envisions a solid-state induction modulator design to drive up to 8 klystrons to 500kV for 3muS at 120 PPS with one modulator (>1,000 megawatt pulse, 500kW average). A prototype modulator is presently under construction, which well power 4 each 5045 SLAC klystron to greater than 380 kV for 3muS (>600 megawatt pulse, >300 kW Ave.). The modulator will be capable of driving the 8 each X band klystrons when they become available. The paper covers the design, construction, fabrication and preliminary testing of the prototype modulator.

  5. Synthesis, structural characterization and conversion of dinuclear iron-sulfur clusters containing the disulfide ligand: [Cp*Fe(μ-η2:η2-bdt)(cis-μ-η11-S2)FeCp*], [Cp*Fe(μ-S(C6H4S2))(cis-μ-η11-S2)FeCp*], and [{Cp*Fe(bdt)}2(trans-μ-η11-S2)].

    PubMed

    Ji, Xiaoxiao; Tong, Peng; Yang, Dawei; Wang, Baomin; Zhao, Jinfeng; Li, Yang; Qu, Jingping

    2017-03-21

    The treatment of [Cp*Fe(μ-η 2 :η 4 -bdt)FeCp*] (1, Cp* = η 5 -C 5 Me 5 , bdt = benzene-1,2-dithiolate) with 1/4 equiv. of elemental sulfur (S 8 ) gave a dinuclear iron-sulfur cluster [Cp*Fe(μ-η 2 :η 2 -bdt)(cis-μ-η 11 -S 2 )FeCp*] (2), which contains a cis-1,2-disulfide ligand. When complex 2 further interacted with 1/8 equiv. of S 8 , another sulfur atom inserted into an Fe-S bond to give a rare product [Cp*Fe(μ-S(C 6 H 4 S 2 ))(cis-μ-η 11 -S 2 )FeCp*] (3). Unexpectedly, a trans-1,2 disulfide-bridged diiron complex [{Cp*Fe(bdt)} 2 (trans-μ-η 11 -S 2 )] (4) was isolated from the reaction of complex 1 with 1/2 equiv. of S 8 , which represents a structural isomer of [2Fe-2S] ferredoxin-type clusters. In addition, cis-1,2-disulfide-bridged complex 3 can slowly convert into trans-1,2-disulfide-bridged complex 4 and the complex [Cp*Fe(μ-η 2 :η 2 -S 2 )(cis-μ-η 11 -S 2 )FeCp*] (5) by self-assembly reaction at ambient temperature, which is evidenced by time-dependent 1 H NMR spectroscopy.

  6. 76 FR 44964 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Evolutionary Power Reactor; Notice of Meeting The ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR) will hold a meeting on August 18, 2011, Room T-2B3, 11545 Rockville Pike...

  7. Evaluation of a prototype flow cytometry test for serodiagnosis of canine visceral leishmaniasis.

    PubMed

    Ker, Henrique Gama; Coura-Vital, Wendel; Aguiar-Soares, Rodrigo Dian de Oliveira; Roatt, Bruno Mendes; das Dores Moreira, Nádia; Carneiro, Cláudia Martins; Machado, Evandro Marques de Menezes; Teixeira-Carvalho, Andréa; Martins-Filho, Olindo Assis; Giunchetti, Rodolfo Cordeiro; Araújo, Márcio Sobreira Silva; Coelho, Eduardo Antonio Ferraz; da Silveira-Lemos, Denise; Reis, Alexandre Barbosa

    2013-12-01

    Diagnosing canine visceral leishmaniasis (CVL) is a critical challenge since conventional immunoserological tests still present some deficiencies. The current study evaluated a prototype flow cytometry serology test, using antigens and fluorescent antibodies that had been stored for 1 year at 4°C, on a broad range of serum samples. Noninfected control dogs and Leishmania infantum-infected dogs were tested, and the prototype test showed excellent performance in differentiating these groups with high sensitivity, specificity, positive and negative predictive values, and accuracy (100% in all analyses). When the CVL group was evaluated according to the dogs' clinical status, the prototype test showed outstanding accuracy in all groups with positive serology (asymptomatic II, oligosymptomatic, and symptomatic). However, in dogs which had positive results by PCR-restriction fragment length polymorphism (RFLP) but negative results by conventional serology (asymptomatic I), serological reactivity was not observed. Additionally, sera from 40 dogs immunized with different vaccines (Leishmune, Leish-Tec, or LBSap) did not present serological reactivity in the prototype test. Eighty-eight dogs infected with other pathogens (Trypanosoma cruzi, Leishmania braziliensis, Ehrlichia canis, and Babesia canis) were used to determine cross-reactivity and specificity, and the prototype test performed well, particularly in dogs infected with B. canis and E. canis (100% and 93.3% specificities, respectively). In conclusion, our data reinforce the potential of the prototype test for use as a commercial kit and highlight its outstanding performance even after storage for 1 year at 4°C. Moreover, the prototype test efficiently provided accurate CVL serodiagnosis with an absence of false-positive results in vaccinated dogs and minor cross-reactivity against other canine pathogens.

  8. Electrically Heated Testing of the Kilowatt Reactor Using Stirling Technology (KRUSTY) Experiment Using a Depleted Uranium Core

    NASA Technical Reports Server (NTRS)

    Briggs, Maxwell H.; Gibson, Marc A.; Sanzi, James

    2017-01-01

    The Kilopower project aims to develop and demonstrate scalable fission-based power technology for systems capable of delivering 110 kW of electric power with a specific power ranging from 2.5 - 6.5 Wkg. This technology could enable high power science missions or could be used to provide surface power for manned missions to the Moon or Mars. NASA has partnered with the Department of Energys National Nuclear Security Administration, Los Alamos National Labs, and Y-12 National Security Complex to develop and test a prototypic reactor and power system using existing facilities and infrastructure. This technology demonstration, referred to as the Kilowatt Reactor Using Stirling TechnologY (KRUSTY), will undergo nuclear ground testing in the summer of 2017 at the Nevada Test Site. The 1 kWe variation of the Kilopower system was chosen for the KRUSTY demonstration. The concept for the 1 kWe flight system consist of a 4 kWt highly enriched Uranium-Molybdenum reactor operating at 800 degrees Celsius coupled to sodium heat pipes. The heat pipes deliver heat to the hot ends of eight 125 W Stirling convertors producing a net electrical output of 1 kW. Waste heat is rejected using titanium-water heat pipes coupled to carbon composite radiator panels. The KRUSTY test, based on this design, uses a prototypic highly enriched uranium-molybdenum core coupled to prototypic sodium heat pipes. The heat pipes transfer heat to two Advanced Stirling Convertors (ASC-E2s) and six thermal simulators, which simulate the thermal draw of full scale power conversion units. Thermal simulators and Stirling engines are gas cooled. The most recent project milestone was the completion of non-nuclear system level testing using an electrically heated depleted uranium (non-fissioning) reactor core simulator. System level testing at the Glenn Research Center (GRC) has validated performance predictions and has demonstrated system level operation and control in a test configuration that replicates the one

  9. Pyrite-H2S/SO4 S isotope exchange at hydrothermal conditions: An experimental study at 300°C and 500 bars

    NASA Astrophysics Data System (ADS)

    Syverson, D. D.; Ono, S.; Seyfried, W. E., Jr.

    2017-12-01

    The rate of exchange and multiple S isotope fractionation between pyrite and dissolved H2S and SO4 was determined at 300°C and 500 bars at physiochemical conditions indicative of natural MOR hydrothermal systems by using the flexible gold cell reactor system [1]. A 34S enriched solution was designed to track reaction progress and to not significantly perturb mass dependent relationships between 33S and 36S, allowing for observations of natural mass dependent fractionation between pyrite and dissolved species during dissolution and recrystallization. The experimental data are compared with previously determined experimental constraints of S isotope exchange between fluid species [2] and with Fe and S isotope experiments conducted at higher temperature and where pyrite was precipitated rapidly from solution at 300 and 350°C and 500 bars [3, 4]. Briefly, the 34S isotope data indicate that the rate of exchange between pyrite and dissolved aqueous species is sluggish, where insignificant exchange occurred after the course of 4000 hours at 300°C, approximately 4%. Furthermore, the 33,36S mineral-fluid data indicate that upon pyrite dissolution, the light isotopes are preferentially removed into solution and incorporated as H2S and SO4-. These data are consistent with natural observations of pyrite-dissolved S disequilibrium and provide important insight towards mineral reactivity and retentiveness of recording mineral formation conditions. [1] Seyfried Jr., W.E., Janecky, D.R. & Berndt, M.E. 1987 Rocking autoclaves for hydrothermal experiments: II. The flexible reaction-cell system. Hydrothermal Experimental Techniques 216-239. [2] Ohmoto, H. & Lasaga, A.C. 1982 Kinetics of reactions between aqueous sulfates and sulfides in hydrothermal systems. Geochimica et Cosmochimica Acta 46, 1727-1745. [3] Syverson, D.D., Borrok, D.M. & Seyfried Jr., W.E. 2013 Experimental determination of equilibrium Fe isotopic fractionation between pyrite and dissolved Fe under hydrothermal

  10. Measurement of /sup 14/C emission rates from a pressurized heavy water reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Joshi, M.L.; Ramamirtham, B.; Soman, S.D.

    Carbon-14 is produced in pressurized heavy water reactors (PHWR), mainly as an activation product in the fuel. It is also produced in the heavy water used as the primary coolant and moderator, and is produced in the air in the annular space between the pressure tube and calandria tubes as well as in the free space in the calandria vault. The production rates in different systems of a PHWR are calculated on the basis of design parameters. During a period of 3 y, /sup 14/C released through the gaseous route has been measured at Rajasthan Atomic Power Station, Kota, India,more » a PHWR unit. These releases have been found to be mainly /sup 14/CO/sub 2/. This reduced form of /sup 14/C is less than 5% of the releases. The normalized releases of /sup 14/C have a geometric mean of 5.17 TBq GWe-1 y-1 and a geometric standard deviation of 1.52. The /sup 14/C present in the form of carbonates in liquid effluents has also been measured and is 0.14% of the gaseous releases.« less

  11. Evaluation of an optimal fill strategy to biodegrade inhibitory wastewater using an industrial prototype discontinuous reactor.

    PubMed

    Buitrón, G; Moreno-Andrade, I; Linares-García, J A; Pérez, J; Betancur, M J; Moreno, J A

    2007-01-01

    This work presents the results and discussions of the application of an optimally controlled influent flow rate strategy to biodegrade, in a discontinuous reactor, a synthetic wastewater constituted by 4-chlorophenol. An aerobic automated discontinuous reactor system of 1.3 m3, with a useful volume of 0.75 m3 and an exchange volume of 60% was used. As part of the control strategy influent is fed into the reactor in such a way as to obtain the maximal degradation rate avoiding inhibition of microorganisms. Such an optimal strategy was able to manage increments of 4-chlorophenol concentrations in the influent between 250 and 1000 mg/L. it was shown that the optimally controlled influent flow rate strategy brings savings in reaction time and flexibility in treating high concentrations of an influent with toxic characteristics.

  12. Requirement of ClC-3 in G0/G1 to S Phase Transition Induced by IGF-1 via ERK1/2-Cyclins Cascade in Multiple Myeloma Cells.

    PubMed

    Du, Yu; Tu, Yong-Sheng; Tang, Yong-Bo; Huang, Yun-Ying; Zhou, Fang-Min; Tian, Tian; Li, Xiao-Yan

    2018-06-01

    ClC-3 is involved in the proliferation and migration of several cancer cells. However, ClC-3 expression and its role of cell-cycle control in multiple myeloma (MM) has not yet been investigated. MM cells were treated with different concentrations of IGF (30, 100, 300 ng/mL), and their proliferation was examined by CCK-8. The effects of ClC-3 on cell cycle progression was detected by flow cytometry. Western blot was used to analyze the relative levels of ClC3, CD138, P21, P27, CDK, p-Erk1/2, and t-Erk1/2 protein expression. Transfection of RPMI8226 with gpClC-3 cDNA and siRNA alters the expression of ClC-3. We compared the expression of ClC-3 in primary myeloma cells and in MM cell lines (U266 and RPMI8266) with that in normal plasma cells (PCs) from normal subjects and found that myeloma cells from patients and MM cell lines had significantly higher expression of ClC-3. Additionally, silencing of ClC-3 with the small interfering RNA (siRNA) that targets human ClC-3 decreased proliferation of RPMI8226 after IGF-1 treatment and slowed cell cycle progression from G0/G1 to S phase, which was associated with diminished phosphorylation of ERK1/2, down-expression of cyclin E, cyclin D1 and up-regulation of p27 and p21. By contrast, overexpression of ClC-3 potentiated cell proliferation induced by IGF-1, raised the percentage of S phase cells, enhanced phosphorylation of ERK1/2, downregulated p27 and p21 and upregulated cyclin E and cyclin D1. ClC-3 accelerated G0/G1 to S phase transition in the cell cycle by modulating ERK1/2 kinase activity and expression of G1/S transition related proteins, making ClC-3 an attractive therapeutic target in MM.

  13. 12. 'Portal Strut for 1 208'101/2' C. to C. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. 'Portal Strut for 1 - 208'-10-1/2' C. to C. End Pins S. Tr. Thro. Skew Span, 6th Crossing of Sacramento River, So. Pac. Co., The Phoenix Bridge Co., C.O. 836D, Drawing No. 12, Scale - 1' = 1', Engineer - B.M. Krohn, May 22nd `01, J.C.S.' - Southern Pacific Railroad Shasta Route, Bridge No. 301.85, Milepost 301.85, Pollard Flat, Shasta County, CA

  14. Studies of Implicit Prototype Extraction In Patients with Mild Cognitive Impairment and Early Alzheimer’s Disease

    PubMed Central

    Nosofsky, Robert M.; Denton, Stephen E.; Zaki, Safa R.; Murphy-Knudsen, Anne F.; Unverzagt, Frederick W.

    2013-01-01

    Studies of incidental category learning support the hypothesis of an implicit prototype-extraction system which is distinct from explicit memory (Smith, 2008). In those studies, patients with explicit-memory impairments due to damage to the medial-temporal lobe performed normally in implicit categorization tasks (Bozoki, Grossman, & Smith, 2006; Knowlton & Squire, 1993). However, alternative interpretations are that: i) even people with impairments to a single memory system have sufficient resources to succeed on the particular categorization tasks that have been tested (Nosofsky & Zaki, 1998; Zaki & Nosofsky, 2001); and ii) working memory can be used at time of test to learn the categories (Palmeri & Flanery, 1999). In the present experiments, patients with amnestic mild cognitive impairment or early Alzheimer’s disease were tested in prototype-extraction tasks to examine these possibilities. In a categorization task involving discrete-feature stimuli, the majority of subjects relied on memories for exceedingly few features, even when the task structure strongly encouraged reliance on broad-based prototypes. In a dot-pattern categorization task, even the memory-impaired patients were able to use working memory at time of test to extract the category structure (at least for the stimulus set used in past work). We argue that the results weaken the past case made in favor of a separate system of implicit-prototype extraction. PMID:22746953

  15. Axisymmetric computational fluid dynamics analysis of Saturn V/S1-C/F1 nozzle and plume

    NASA Technical Reports Server (NTRS)

    Ruf, Joseph H.

    1993-01-01

    An axisymmetric single engine Computational Fluid Dynamics calculation of the Saturn V/S 1-C vehicle base region and F1 engine plume is described. There were two objectives of this work, the first was to calculate an axisymmetric approximation of the nozzle, plume and base region flow fields of S1-C/F1, relate/scale this to flight data and apply this scaling factor to a NLS/STME axisymmetric calculations from a parallel effort. The second was to assess the differences in F1 and STME plume shear layer development and concentration of combustible gases. This second piece of information was to be input/supporting data for assumptions made in NLS2 base temperature scaling methodology from which the vehicle base thermal environments were being generated. The F1 calculations started at the main combustion chamber faceplate and incorporated the turbine exhaust dump/nozzle film coolant. The plume and base region calculations were made for ten thousand feet and 57 thousand feet altitude at vehicle flight velocity and in stagnant freestream. FDNS was implemented with a 14 species, 28 reaction finite rate chemistry model plus a soot burning model for the RP-1/LOX chemistry. Nozzle and plume flow fields are shown, the plume shear layer constituents are compared to a STME plume. Conclusions are made about the validity and status of the analysis and NLS2 vehicle base thermal environment definition methodology.

  16. The process of S-nitrosation in sGC β1(1-194) revealed by infrared spectroscopy

    NASA Astrophysics Data System (ADS)

    Liu, Li; Wang, Dandan; Xu, Haoran; Mi, Mengdan; Li, Zhengqiang

    2015-06-01

    Soluble guanylate cyclase (sGC) is the most important receptor for the signaling molecule NO. NO activates sGC by binding to its heme cofactor and reacts with free thiols in the protein itself. The S-nitrosation of cysteine thiols affects the activity of soluble guanylate cyclase (sGC). In this study, infrared (IR) spectroscopy and site-directed mutagenesis were used to investigate S-H vibration and the process of S-nitrosation in the β1 subunit (amino acids 1-194) of sGC. Fourier transform IR spectroscopy revealed that wild-type and mutants (C78S and C122S) of sGC β1(1-194) exhibited S-H peaks around 2560 cm-1. The signals were attenuated in the IR spectra of S-nitrosoglutathione-treated mutants, demonstrating that S-nitrosation in sGC β1(1-194) occured at residues C78 and C122, and the process of the reaction was GSNO concentration-dependent.

  17. Discrepancies Between Prototype International Data Centre, International Seismological Centre & USGS Seismic Magnitudes

    DTIC Science & Technology

    2007-03-01

    International Seismological C -DTRA 01-00-C-0074 Centre & USGS Seismic Magnitudes PE - 462D PR- AE TA - EJ 6. AUTHOR(S) WU - DH0203 9 Paul G. Richards, John P...Defense Threat Reduction Agency 8725 John J. Kingman Road, MS 6201 "a Fort Belvoir, VA 22060-6201 ’ DTRA-TR-06-15 Discrepancies Between Prototype...0 Z March 2007 "I 20070420395 Li DTRA 01 -00-C-0074 M Paul G. Richards, et al. Prepared by: Columbia University Lamont-Doherty Earth Observatory 61

  18. Joule-Heated Molten Regolith Electrolysis Reactor Concepts for Oxygen and Metals Production on the Moon and Mars

    NASA Technical Reports Server (NTRS)

    Sibille, Laurent; Dominques, Jesus A.

    2012-01-01

    The maturation of Molten Regolith Electrolysis (MRE) as a viable technology for oxygen and metals production on explored planets relies on the realization of the self-heating mode for the reactor. Joule heat generated during regolith electrolysis creates thermal energy that should be able to maintain the molten phase (similar to electrolytic Hall-Heroult process for aluminum production). Self-heating via Joule heating offers many advantages: (1) The regolith itself is the crucible material, it protects the vessel walls (2) Simplifies the engineering of the reactor (3) Reduces power consumption (no external heating) (4) Extends the longevity of the reactor. Predictive modeling is a tool chosen to perform dimensional analysis of a self-heating reactor: (1) Multiphysics modeling (COMSOL) was selected for Joule heat generation and heat transfer (2) Objective is to identify critical dimensions for first reactor prototype.

  19. Rapid preparation of high electrochemical performance LiFePO4/C composite cathode material with an ultrasonic-intensified micro-impinging jetting reactor.

    PubMed

    Dong, Bin; Huang, Xiani; Yang, Xiaogang; Li, Guang; Xia, Lan; Chen, George

    2017-11-01

    A joint chemical reactor system referred to as an ultrasonic-intensified micro-impinging jetting reactor (UIJR), which possesses the feature of fast micro-mixing, was proposed and has been employed for rapid preparation of FePO 4 particles that are amalgamated by nanoscale primary crystals. As one of the important precursors for the fabrication of lithium iron phosphate cathode, the properties of FePO 4 nano particles significantly affect the performance of the lithium iron phosphate cathode. Thus, the effects of joint use of impinging stream and ultrasonic irradiation on the formation of mesoporous structure of FePO 4 nano precursor particles and the electrochemical properties of amalgamated LiFePO 4 /C have been investigated. Additionally, the effects of the reactant concentration (C=0.5, 1.0 and 1.5molL -1 ), and volumetric flow rate (V=17.15, 51.44, and 85.74mLmin -1 ) on synthesis of FePO 4 ·2H 2 O nucleus have been studied when the impinging jetting reactor (IJR) and UIJR are to operate in nonsubmerged mode. It was affirmed from the experiments that the FePO 4 nano precursor particles prepared using UIJR have well-formed mesoporous structures with the primary crystal size of 44.6nm, an average pore size of 15.2nm, and a specific surface area of 134.54m 2 g -1 when the reactant concentration and volumetric flow rate are 1.0molL -1 and 85.74mLmin -1 respectively. The amalgamated LiFePO 4 /C composites can deliver good electrochemical performance with discharge capacities of 156.7mAhg -1 at 0.1C, and exhibit 138.0mAhg -1 after 100 cycles at 0.5C, which is 95.3% of the initial discharge capacity. Copyright © 2017. Published by Elsevier B.V.

  20. CATALYTIC HYDRODECHLORINATION OF 1,3-DICHLOROPROPENE. (R826694C626)

    EPA Science Inventory

    The hydrodechlorination reactions of 1,3-dichloropropene, a component of the waste stream from epichlorohydrin manufacturing, were examined over a variety of catalysts in a packed-bed microreactor. The reactor operated between 7.5–9 Mpa and 325°C and rates of ...

  1. Thoracoscopic anatomical subsegmentectomy of the right S2b + S3 using a 3D printing model with rapid prototyping.

    PubMed

    Nakada, Takeo; Akiba, Tadashi; Inagaki, Takuya; Morikawa, Toshiaki

    2014-10-01

    Thoracoscopic segmentectomies and subsegmentectomies are more difficult than lobectomy because of the complexity of the procedure; therefore, preoperative decision-making and surgical procedure planning are essential. In the literature, we could successfully perform thoracoscopic anatomical subsegmentectomy of the right S2b + S3 using a 3D printing model with rapid prototyping. This innovative surgical support model is extremely useful for planning a surgical procedure and identifying the surgical margin. © The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  2. Reactor for exothermic reactions

    DOEpatents

    Smith, Jr., Lawrence A.; Hearn, Dennis; Jones, Jr., Edward M.

    1993-01-01

    A liquid phase process for oligomerization of C.sub.4 and C.sub.5 isoolefins or the etherification thereof with C.sub.1 to C.sub.6 alcohols wherein the reactants are contacted in a reactor with a fixed bed acid cation exchange resin catalyst at an LHSV of 5 to 20, pressure of 0 to 400 psig and temperature of 120.degree. to 300.degree. F. Wherein the improvement is the operation of the reactor at a pressure to maintain the reaction mixture at its boiling point whereby at least a portion but less than all of the reaction mixture is vaporized. By operating at the boiling point and allowing a portion of the reaction mixture to vaporize, the exothermic heat of reaction is dissipated by the formation of more boil up and the temperature in the reactor is controlled.

  3. Reactor for exothermic reactions

    DOEpatents

    Smith, L.A. Jr.; Hearn, D.; Jones, E.M. Jr.

    1993-03-02

    A liquid phase process is described for oligomerization of C[sub 4] and C[sub 5] isoolefins or the etherification thereof with C[sub 1] to C[sub 6] alcohols wherein the reactants are contacted in a reactor with a fixed bed acid cation exchange resin catalyst at an LHSV of 5 to 20, pressure of 0 to 400 psig and temperature of 120 to 300 F. Wherein the improvement is the operation of the reactor at a pressure to maintain the reaction mixture at its boiling point whereby at least a portion but less than all of the reaction mixture is vaporized. By operating at the boiling point and allowing a portion of the reaction mixture to vaporize, the exothermic heat of reaction is dissipated by the formation of more boil up and the temperature in the reactor is controlled.

  4. Development and evaluation of a prototype life preserver.

    DOT National Transportation Integrated Search

    1985-09-01

    The purpose of this study was to develop a prototype life preserver that included provisions for: : 1.increased thermal protection in the event of accidental immersion in cold water, : 2.35 pounds of buoyancy, : 3.a doning [sic] time of 15 s for an a...

  5. 49 CFR 372.205 - Charleston, S.C.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... from a point beyond such zone, is partially exempt from regulation under 49 U.S.C. 13506(b)(1) includes and is comprised of all points as follows: (a) The municipality of Charleston, S.C., itself; (b) All... Charleston County, S.C., which are not within the areas described in paragraph (b) of this section; and those...

  6. A Prototype Indicators System for U.S. Climate Changes, Impacts, Vulnerabilities, and Responses

    NASA Astrophysics Data System (ADS)

    Kenney, M. A.; Janetos, A.; Gerst, M.; Lloyd, A.; Wolfinger, J. F.; Reyes, J. J.; Anderson, S. M.; Pouyat, R. V.

    2015-12-01

    Indicators are observations or calculations that are used to systematically report or forecast social and biophysical conditions over time. When the purpose of indicators is to, in part, provide complex scientific information that is understood by non-scientists and included in decision processes, the choice of indicators requires a structured process that includes co-production among a range of actors, including scientists, decision-makers, and a range of stakeholders. Here we describe recommendations on a vision and a prototype created for an indicators system, we term the National Climate Indicators System (NCIS). The goal of the NCIS is to create a system of physical, natural, and societal indicators to communicate and inform decisions about climate changes, impacts, vulnerabilities, and responses. The process of generating the indicator system involved input from over 200 subject-matter experts. Organized into 13 teams, experts created conceptual models of their respective sectors to generate an initial recommended set of indicators. A subset of indicators, which could be immediately implemented, were prototyped for the U.S. Global Change Research Program (USGCRP) a Federal program that coordinates and supports integration of global change research across the government. USGCRP reviewed the recommendations (Kenney et al., 2014) and prototypes provided by the scientific experts, and recently launched 14 indicators as proof-of-concept in support of a sustained National Climate Assessment and to solicit feedback from the users. Social science research is currently being undertaken in order to evaluate how well the prototype indicators communicate science to non-scientists, the usability of indicator system portal by scientists and decision-makers, and the development of information visualization guidelines to improve visual communication effectiveness. The goal of such efforts would be to provide input into the development of a more comprehensive USGCRP indicator

  7. Hemoglobin C, S-C, and E Diseases

    MedlinePlus

    ... quickly than others, resulting in chronic anemia. Hemoglobin C disease Hemoglobin C disease occurs mostly in blacks. ... a common complication of hemoglobin C disease. Hemoglobin S-C disease Hemoglobin S-C disease occurs in people who ...

  8. Comet C2012 S1 (ISON)s Carbon-rich and Micron-size-dominated Coma Dust

    NASA Technical Reports Server (NTRS)

    Wooden, D.; De Buizer, J.; Kelley, M.; Sitko, M.; Woodward, C.; Harker, D.; Reach, W.; Russell, R.; Kim, D.; Yanamadra-Fisher, P.; hide

    2014-01-01

    Comet C/2012 S1 (ISON) was unique in that it was a dynamically new comet derived from the Nearly Isotropic Oort cloud reservoir of comets with a sun-grazing orbit. We present thermal models for comet ISON (rh approx.1.15 AU, 2013-Oct-25 11:30 UT) that reveal comet ISON's dust was carbon-rich and dominated by a narrow size distribution dominated by approx. micron-sized grains. We constrained the models by our SOFIA FORCAST photometry at 11.1, 19.7 and 31.5 microns and by a silicate feature strength of approx.1.1 and an 8-13microns continuum greybody color temperature of approx. 275-280 K (using Tbb ? r-0.5 h and Tbb approx. 260-265 K from Subaru COMICS, 2013-Oct-19 UT)[1,2]. N-band spectra of comet ISON with the BASS instrument on the NASA IRTF (2013-Nov-11-12 UT) show a silicate feature strength of approx. 1.1 and an 11.2microns forsterite peak.[3] Our thermal models yield constraints the dust composition as well as grain size distribution parameters: slope, peak grain size, porosity. Specifically, ISON's dust has a low silicate-to- amorphous carbon ratio (approx. 1:9), and the coma size distribution has a steep slope (N4.5) such that the coma is dominated by micron-sized, moderately porous, carbon-rich dust grains. The N-band continuum color temperature implies submicronto micron-size grains and the steep fall off of the SOFIA far-IR photometry requires the size distribution to have fewer relative numbers of larger and cooler grains compared to smaller and hotter grains. A proxy for the dust production rate is f? approx.1500 cm, akin to Af?. ISON has a moderate-to-low dust-to-gas ratio. Comet ISON's dust grain size distribution does not appear similar to the few well-studied long-period Nearly Isotropic Comets (NICs), namely C/1995 O1 (Hale-Bopp) and C/2001 Q4 (NEAT) that had smaller and/or more highly porous grains and larger sizes, or C/2007 N4 (Lulin) and C/2006 P1 (McNaught) that had large and/or compact grains. Radial transport to comet-forming disk distances

  9. 45 CFR 704.1 - Material available pursuant to 5 U.S.C. 552.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Section 704.1 Public Welfare Regulations Relating to Public Welfare (Continued) COMMISSION ON CIVIL RIGHTS... Civil Rights implementing the Freedom of Information Act, 5 U.S.C. 552. These regulations inform the... following terms are defined as indicated: Commission means the United States Commission on Civil Rights...

  10. Bethe-Salpeter wave functions of ηc(1S, 2S) and ψ(1S, 2S) states: local-potential description of the charmonium system revisited

    NASA Astrophysics Data System (ADS)

    Nochi, Kazuki; Kawanai, Taichi; Sasaki, Shoichi

    2018-03-01

    The quark potential models with an energy-independent central potential have been successful for understanding the conventional charmonium states especially below the open charm threshold. As one might consider, however, the interquark potential is in general energy-dependent, and its tendency gets stronger in higher lying states. Confirmation of whether the interquark potential is energy-independent is also important to verify the validity of the quark potential models. In this talk, we examine the energy dependence of the charmonium potential, which can be determined from the Bethe-Salpeter (BS) amplitudes of cc̅ mesons in lattice QCD.We first calculate the BS amplitudes of radially excited charmonium states, the ηc(2S) and ψ(2S) states, using the variational method and then determine both the quark kinetic mass and the charmonium potential within the HAL QCD method. Through a direct comparison of charmonium potentials determined from both the 1S and 2S states, we confirm that neither the central nor spin-spin potential shows visible energy dependence at least up to 2S state.

  11. Prototype to measure bracket debonding force in vivo

    PubMed Central

    Tonus, Jéssika Lagni; Manfroi, Fernanda Borguetti; Borges, Gilberto Antonio; Grigolo, Eduardo Correa; Helegda, Sérgio; Spohr, Ana Maria

    2017-01-01

    ABSTRACT Introduction: Material biodegradation that occurs in the mouth may interfere in the bonding strength between the bracket and the enamel, causing lower bond strength values in vivo, in comparison with in vitro studies. Objective: To develop a prototype to measure bracket debonding force in vivo and to evaluate, in vitro, the bond strength obtained with the prototype. Methods: A original plier (3M Unitek) was modified by adding one strain gauge directly connected to its claw. An electronic circuit performed the reading of the strain gauge, and the software installed in a computer recorded the values of the bracket debonding force, in kgf. Orthodontic brackets were bonded to the facial surface of 30 bovine incisors with adhesive materials. In Group 1 (n = 15), debonding was carried out with the prototype, while tensile bond strength testing was performed in Group 2 (n = 15). A universal testing machine was used for the second group. The adhesive remnant index (ARI) was recorded. Results: According to Student’s t test (α = 0.05), Group 1 (2.96 MPa) and Group 2 (3.08 MPa) were not significantly different. ARI score of 3 was predominant in the two groups. Conclusion: The prototype proved to be reliable for obtaining in vivo bond strength values for orthodontic brackets. PMID:28444011

  12. Comet C/2012 S1 (ISON)'s carbon-rich and micron-size-dominated coma dust

    NASA Astrophysics Data System (ADS)

    Wooden, D.; De Buizer, J.; Kelley, M.; Sitko, M.; Woodward, C.; Harker, D.; Reach, W.; Russell, R.; Kim, D.; Yanamadra-Fisher, P.; Lisse, C.; de Pater, I.; Gehrz, R.; Kolokolova, L.

    2014-07-01

    Comet C/2012 S1 (ISON) was unique in that it was a dynamically new comet derived from the Nearly Isotropic Oort cloud reservoir of comets with a sun-grazing orbit. We present thermal models for comet ISON (r_h ˜ 1.15 au, 2013-Oct-25 11:30 UT) that reveal comet ISON's dust was carbon-rich and dominated by a steep (and therefor narrow) grain size distribution (GSD) dominated by ˜ micron-sized grains. We constrained the models by our SOFIA FORCAST photometry at 11.1, 19.7 and 31.5 μ m and by a silicate feature strength of ˜1.1 and an 8-13 μ m continuum greybody color temperature of ˜275-280 K (using T_{bb}∝ {r}_h^{-0.5} and T_{bb}˜260-265 K from Subaru+COMICS, 2013-Oct-19 UT) [1,2]. Spectra of comet ISON with IRTF+BASS (2013-Nov-11-12 UT) also show a silicate feature strength of ˜1.1 as well as an 11.2 μ m forsterite peak [3]. Our thermal models [6], which employ 0.1-1000 μ m grains, yield constraints for the dust composition as well as GSD parameters of slope, peak grain size, porosity: ISON's dust has a low silicate-to-amorphous carbon ratio (˜1:9), the GSD has a steep slope (N≃4.5), a peak grain radius of ˜0.7 μ m, and moderately porous grains. Specifically, the 8-13 μ m continuum color temperature implies submicron- to micron-size grains and the steep fall off of the SOFIA far-IR photometry requires the GSD to have fewer relative numbers of larger and cooler grains compared to smaller and hotter grains. A IR proxy for the dust production rate is ɛ f ρ ˜ 1500 cm [4], which is akin to but larger than Afρ in scattered light (2013-Oct-20 UT, Afρ=796 cm(±5 %) in V-band from Swift) [5]. Also, ISON had a moderate-to-low dust-to-gas ratio [6]. Comet ISON's dust composition and GSD properties are distinct from the few well-studied long-period Nearly Isotropic Comets (NICs) that all had 'typical' GSD slopes (3.4≤N≤3.7) and silicate-to-amorphous carbon ratios ≫1 as well as the following properties: C/1995 O1 (Hale-Bopp)[7,8,9,10] and C/2001 Q4

  13. Lessons Learned about Liquid Metal Reactors from FFTF Experience

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wootan, David W.; Casella, Andrew M.; Omberg, Ronald P.

    2016-09-20

    The Fast Flux Test Facility (FFTF) is the most recent liquid-metal reactor (LMR) to operate in the United States, from 1982 to 1992. FFTF is located on the DOE Hanford Site near Richland, Washington. The 400-MWt sodium-cooled, low-pressure, high-temperature, fast-neutron flux, nuclear fission test reactor was designed specifically to irradiate Liquid Metal Fast Breeder Reactor (LMFBR) fuel and components in prototypical temperature and flux conditions. FFTF played a key role in LMFBR development and testing activities. The reactor provided extensive capability for in-core irradiation testing, including eight core positions that could be used with independent instrumentation for the test specimens.more » In addition to irradiation testing capabilities, FFTF provided long-term testing and evaluation of plant components and systems for LMFBRs. The FFTF was highly successful and demonstrated outstanding performance during its nearly 10 years of operation. The technology employed in designing and constructing this reactor, as well as information obtained from tests conducted during its operation, can significantly influence the development of new advanced reactor designs in the areas of plant system and component design, component fabrication, fuel design and performance, prototype testing, site construction, and reactor operations. The FFTF complex included the reactor, as well as equipment and structures for heat removal, containment, core component handling and examination, instrumentation and control, and for supplying utilities and other essential services. The FFTF Plant was designed using a “system” concept. All drawings, specifications and other engineering documentation were organized by these systems. Efforts have been made to preserve important lessons learned during the nearly 10 years of reactor operation. A brief summary of Lessons Learned in the following areas will be discussed: Acceptance and Startup Testing of FFTF FFTF Cycle Reports« less

  14. NUCLEAR REACTOR CORE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Preece, G.E.; Bell, F.R.; Page, R.W.

    1963-03-01

    A nuclear reactor core is described. It contains fuel in the form of blocks or pellets that have a grooved, wrinkled, or corrugated surface to provide a greater radiating surface area. The surfaces of spaces in the core are correspondingly corrugated for maximum heat exchange area. (C.E.S.)

  15. Simultaneous C and N removal from saline salmon effluents in filter reactors comprising anoxic-anaerobic-aerobic processes: effect of recycle ratio.

    PubMed

    Giustinianovich, Elisa A; Aspé, Estrella R; Huiliñir, César E; Roeckel, Marlene D

    2014-01-01

    Salmon processing generates saline effluents with high protein load. To treat these effluents, three compact tubular filter reactors were installed and an integrated anoxic/anaerobic/aerobic process was developed with recycling flow from the reactor's exit to the inlet stream in order to save organic matter (OM) for denitrification. The reactors were aerated in the upper section with recycle ratios (RR) of 0, 2, and 10, respectively, at 30°C. A tubular reactor behave as a plug flow reactor when RR = 0, and as a mixed flow reactor when recycle increases, thus, different RR values were used to evaluate how it affects the product distribution and the global performance. Diluted salmon process effluent was prepared as substrate. Using loads of 1.0 kg COD m(-3)d(-1) and 0.15 kg total Kjeldahl nitrogen (TKN) m(-3)d(-1) at HRT of 2 d, 100% removal efficiencies for nitrite and nitrate were achieved in the anoxic-denitrifying section without effect of the dissolved oxygen in the recycled flow on denitrification. Removals >98% for total organic carbon (TOC) was achieved in the three reactors. The RR had no effect on the TOC removal; nevertheless a higher efficiency in total nitrogen removal in the reactor with the highest recycle ratio was observed: 94.3% for RR = 10 and 46.6% for RR = 2. Results showed that the proposed layout with an alternative distribution in a compact reactor can efficiently treat high organic carbon and nitrogen concentrations from a saline fish effluent with OM savings in denitrification.

  16. US NDC Modernization Iteration E1 Prototyping Report: Processing Control Framework

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Prescott, Ryan; Hamlet, Benjamin R.

    2014-12-01

    During the first iteration of the US NDC Modernization Elaboration phase (E1), the SNL US NDC modernization project team developed an initial survey of applicable COTS solutions, and established exploratory prototyping related to the processing control framework in support of system architecture definition. This report summarizes these activities and discusses planned follow-on work.

  17. sCO2 Brayton Cycle: Roadmap to sCO2 Power Cycles NE Commercial Applications.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mendez Cruz, Carmen Margarita; Rochau, Gary E.

    The mission of the Energy Conversion (EC) area of the Advanced Reactor Technology (ART) program is to commercialize the sCO2 Brayton cycle for Advance Reactors and for the Supercritical Transformational Electric Production (STEP) program. The near-term objective of the EC team efforts is to support the development of a commercially scalable Recompression Closed Brayton Cycle (RCBC) to be constructed for the first STEP demonstration system with the lowest risk possible. This document details the status of technology, policy and market considerations, documentation of gaps and needs, and outlines the steps necessary for the successful development and deployment of commercial sCO2more » Brayton Power Systems along the path to nuclear reactor applications. Document Control Version Creation Date Revisions Created By Release Date 1.0 2/29/2016 Preliminary Draft Mendez, C. 3/2/2016 2.0 7/29/2016 Preliminaty/Partial Report -- updated Focus Area structure, added commercial path forward Mendez, C. 8/10/16 3.0 5/1/2018 Updated Roadmap supports timeline changes and inclusion of grid qualification goals Mendez, C. 6/6/18« less

  18. Prototypic chromatin insulator cHS4 protects retroviral transgene from silencing in Schistosoma mansoni

    PubMed Central

    Suttiprapa, Sutas; Rinaldi, Gabriel; Brindley, Paul J.

    2011-01-01

    Vesicular stomatitis virus glycoprotein (VSVG) pseudotyped murine leukemia virus (MLV) virions can transduce schistosomes, leading to chromosomal integration of reporter transgenes. To develop VSVG-MLV for functional genomics in schistosomes, the influence of the chicken β-globin cHS4 element, a prototypic chromatin insulator, on transgene expression was examined. Plasmid pLNHX encoding the MLV 5′- and 3′-Long Terminal Repeats (LTRs) flanking the neomycin phosphotransferase gene (neo) was modified to include, within the U3 region of the 3′-LTR, active components of cHS4 insulator, the 250 bp core fused to the 400 bp 3′-region. Cultured larvae of Schistosoma mansoni were transduced with virions from producer cells transfected with control or cHS4-bearing plasmids. Schistosomules transduced with cHS4 virions expressed two to 20 times higher levels of neo than controls, while carrying comparable numbers of integrated proviral transgenes. The findings not only demonstrated that cHS4 was active in schistosomes but also they represent the first report of activity of cHS4 in any Lophotrochozoan species, which has significant implications for evolutionary conservation of heterochromatin regulation. The findings advance prospects for transgenesis in functional genomics of the schistosome genome to discover intervention targets because they provide the means to enhance and extend transgene activity including for vector based RNA interference. PMID:21918820

  19. Performance of intermittent aeration reactor on NH4-N removal from groundwater resources.

    PubMed

    Khanitchaidecha, W; Nakamura, T; Sumino, T; Kazama, F

    2010-01-01

    To study the effect of intermittent aeration period on ammonium-nitrogen (NH4-N) removal from groundwater resources, synthetic groundwater was prepared and three reactors were operated under different conditions--"reactor A" under continuous aeration, "reactor B" under 6 h intermittent aeration, and "reactor C" under 2 h intermittent aeration. To facilitate denitrification simultaneously with nitrification, "acetate" was added as an external carbon source with step-wise increase from 0.5 to 1.5 C/N ratio, where C stands for total carbon content in the system, and N for NH4-N concentration in the synthetic groundwater. Results show that complete NH4-N removal was obtained in "reactor B" and "reactor C" at 1.3 and 1.5 C/N ratio respectively; and partial NH4-N removal in "reactor A". These results suggest that intermittent aeration at longer interval could enhance the reactor performance on NH4-N removal in terms of efficiency and low external carbon requirement. Because of consumption of internal carbon by the process, less amount of external carbon is required. Further increase in carbon in a form of acetate (1.5 to 2.5 C/N ratios) increases removal rate (represented by reaction rate coefficient (k) of kinetic equation) as well as occurrence of free cells. It suggests that the operating condition at reactor B with 1.3 C/N ratio is more appropriate for long-term operation at a pilot-scale.

  20. US NDC Modernization Iteration E1 Prototyping Report: User Interface Framework

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lober, Randall R.

    2014-12-01

    During the first iteration of the US NDC Modernization Elaboration phase (E1), the SNL US NDC modernization project team completed an initial survey of applicable COTS solutions, and established exploratory prototyping related to the User Interface Framework (UIF) in support of system architecture definition. This report summarizes these activities and discusses planned follow-on work.

  1. US NDC Modernization Iteration E1 Prototyping Report: Common Object Interface

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lewis, Jennifer E.; Hess, Michael M.

    2014-12-01

    During the first iteration of the US NDC Modernization Elaboration phase (E1), the SNL US NDC modernization project team completed an initial survey of applicable COTS solutions, and established exploratory prototyping related to the Common Object Interface (COI) in support of system architecture definition. This report summarizes these activities and discusses planned follow-on work.

  2. 77 FR 36581 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Advanced Pressurized Power Reactor; Notice of Meeting The ACRS Subcommittee on U.S. Advanced Pressurized Power Reactor (US-APWR) will hold a meeting on July 9-10, 2012, Room T-2B3, 11545...

  3. Far-UV observations of comet C/2012 S1 (ISON) with FORTIS

    NASA Astrophysics Data System (ADS)

    McCandliss, Stephan R.; Feldman, Paul D.; Weaver, Harold A.; Fleming, Brian; Redwine, Keith; Li, Mary J.; Kutyrev, Alexander; Moseley, Samuel H.

    2015-01-01

    Far-UV imagery and objective grating spectroscopy of comet C/2012 S1 (ISON) were acquired from NASA sounding rocket 36.296 UG, launched on 20 November 2013 at 04:40 MST (20.48 Nov 2013 UT), 8.32 days pre-perihelion, from the White Sands Missile Range, NM. The comet was 0.1° below ground horizon, 0.44 AU from the Sun, 0.86 AU from the Earth, and at a solar elongation of 26.3°. The payload reached an apogee of 279 km and the total time pointed at the comet was 353 s. At the time of launch ISON was undergoing a factor of 5 increase in water production rate, going from 3.5e29 to 19.6e29 molecules s-1between 19.6 and 21.6 Nov (Combi et al. 2014), marking what is thought to be a final fragmentation event (Sekanina & Kracht 2014). Our instrument, a wide-field multi-object spectro-telescope called FORTIS (Far-UV Off Rowland-circle Telescope for Imaging and Spectroscopy), observed Lyα emissions in an objective grating mode through an open microshutter array, developed at the Goddard Space Flight Center, over a (1/2°)2 field-of-view. After accounting for slit losses and deadtime corrections we find a preliminary lower limit to the Lyα surface brightness of ~ 400 kilorayleighs, yielding a hydrogen production rate of QH ~ 5e29 atoms s-1, in reasonable agreement with the Combi result. We also acquired a broadband image of the comet in the 1280 to 1900 Å bandpass. This image shows a drop in count rate proportional to altitude caused by increased absorption of cometary emissions by terrestrial O2 located in the lower thermosphere. O2 absorption acts as a selective time dependent filter that attenuates cometary emissions from different atomic and molecular species at different rates during descent. Preliminary analysis suggests that the dominant species in a (1e5 km)2 nuclear region is neutral carbon. The radial profile in comparison to a Haser model suggests that the C parent molecule had a lifetime (at 1 AU) ~ 105 s; much shorter than the expected lifetime of CO. We

  4. Morpheus Campaign 1C

    NASA Image and Video Library

    2014-03-05

    CAPE CANAVERAL, Fla. – Engineers and technicians prepare the Project Morpheus prototype lander for its sixth free flight test from a launch pad at the north end of the Shuttle Landing Facility at NASA’s Kennedy Space Center in Florida. The 82-second test began at 11:32 a.m. EST with the Morpheus lander launching from the ground over a flame trench and ascending to 465 feet. The lander flew forward, covering 633 feet while performing a 55-foot divert to emulate a hazard avoidance maneuver before descending and landing on a dedicated pad inside the automated landing and hazard avoidance technology, or ALHAT, hazard field. Morpheus landed 10 inches west of its intended target. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, or green propellants, into a fully-operational lander that could deliver cargo to other planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Kim Shiflett

  5. Morpheus Campaign 1C

    NASA Image and Video Library

    2014-03-05

    CAPE CANAVERAL, Fla. – The Project Morpheus prototype lander begins to ascend on its sixth free flight test at the north end of the Shuttle Landing Facility at NASA’s Kennedy Space Center in Florida. The 82-second test began at 11:32 a.m. EST with the Morpheus lander launching from the ground over a flame trench and ascending to 465 feet. The lander flew forward, covering 633 feet while performing a 55-foot divert to emulate a hazard avoidance maneuver before descending and landing on a dedicated pad inside the automated landing and hazard avoidance technology, or ALHAT, hazard field. Morpheus landed 10 inches west of its intended target. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, or green propellants, into a fully-operational lander that could deliver cargo to other planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Kim Shiflett

  6. Morpheus Campaign 1C

    NASA Image and Video Library

    2014-03-05

    CAPE CANAVERAL, Fla. – The Project Morpheus prototype lander soars high after launching on its sixth free flight test at the north end of the Shuttle Landing Facility at NASA’s Kennedy Space Center in Florida. The 82-second test began at 11:32 a.m. EST with the Morpheus lander launching from the ground over a flame trench and ascending to 465 feet. The lander flew forward, covering 633 feet while performing a 55-foot divert to emulate a hazard avoidance maneuver before descending and landing on a dedicated pad inside the automated landing and hazard avoidance technology, or ALHAT, hazard field. Morpheus landed 10 inches west of its intended target. Project Morpheus tests NASA’s ALHAT and an engine that runs on liquid oxygen and methane, or green propellants, into a fully-operational lander that could deliver cargo to other planetary surfaces. The landing facility provides the lander with the kind of field necessary for realistic testing, complete with rocks, craters and hazards to avoid. Morpheus’ ALHAT payload allows it to navigate to clear landing sites amidst rocks, craters and other hazards during its descent. Project Morpheus is being managed under the Advanced Exploration Systems, or AES, Division in NASA’s Human Exploration and Operations Mission Directorate. The efforts in AES pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. For more information on Project Morpheus, visit http://morpheuslander.jsc.nasa.gov/. Photo credit: NASA/Kim Shiflett

  7. Application of a Virtual Reactivity Feedback Control Loop in Non-Nuclear Testing of a Fast Spectrum Reactor

    NASA Technical Reports Server (NTRS)

    Bragg-Sitton, Shannon M.; Forsbacka, Matthew

    2004-01-01

    For a compact, fast-spectrum reactor, reactivity feedback is dominated by core deformation at elevated temperature. Given the use of accurate deformation measurement techniques, it is possible to simulate nuclear feedback in non-nuclear electrically heated reactor tests. Implementation of simulated reactivity feedback in response to measured deflection is being tested at the NASA Marshall Space Flight Center Early Flight Fission Test Facility (EFF-TF). During tests of the SAFE-100 reactor prototype, core deflection was monitored using a high resolution camera. "virtual" reactivity feedback was accomplished by applying the results of Monte Carlo calculations (MCNPX) to core deflection measurements; the computational analysis was used to establish the reactivity worth of van'ous core deformations. The power delivered to the SAFE-100 prototype was then dusted accordingly via kinetics calculations, The work presented in this paper will demonstrate virtual reactivity feedback as core power was increased from 1 kilowatt(sub t), to 10 kilowatts(sub t), held approximately constant at 10 kilowatts (sub t), and then allowed to decrease based on the negative thermal reactivity coefficient.

  8. MATERNAL REPRESENTATIONS AND INFANT ATTACHMENT: AN EXAMINATION OF THE PROTOTYPE HYPOTHESIS.

    PubMed

    Madigan, Sheri; Hawkins, Erinn; Plamondon, Andre; Moran, Greg; Benoit, Diane

    2015-01-01

    The prototype hypothesis suggests that attachment representations derived in infancy continue to influence subsequent relationships over the life span, including those formed with one's own children. In the current study, we test the prototype hypothesis by exploring (a) whether child-specific representations following actual experience in interaction with a specific child impacts caregiver-child attachment over and above the prenatal forecast of that representation and (b) whether maternal attachment representations exert their influence on infant attachment via the more child-specific representation of that relationship. In a longitudinal study of 84 mother-infant dyads, mothers' representations of their attachment history were obtained prenatally with the Adult Attachment Interview (AAI; M. Main, R. Goldwyn, & E. Hesse, 2002), representations of relationship with a specific child were assessed with the Working Model of the Child Interview (WMCI; C.H. Zeanah, D. Benoit, & L. Barton, 1986), collected both prenatally and again at infant age 11 months, and infant attachment was assessed in the Strange Situation Procedure (M.D.S. Ainsworth, M.C. Blehar, E. Walters, & S. Wall, 1978) when infants were 11 months of age. Consistent with the prototype hypothesis, considerable correspondence was found between mothers' AAI and WMCI classifications. A mediation analysis showed that WMCI fully accounted for the association between AAI and infant attachment. Postnatal WMCI measured at 11 months' postpartum did not add to the prediction of infant attachment, over and above that explained by the prenatal WMCI. Implications for these findings are discussed. © 2015 Michigan Association for Infant Mental Health.

  9. Examination of Surface Deposits on Oldbury Reactor Core Graphite to Determine the Concentration and Distribution of 14C.

    PubMed

    Payne, Liam; Heard, Peter J; Scott, Thomas B

    2016-01-01

    Pile Grade A graphite was used as a moderator and reflector material in the first generation of UK Magnox nuclear power reactors. As all of these reactors are now shut down there is a need to examine the concentration and distribution of long lived radioisotopes, such as 14C, to aid in understanding their behaviour in a geological disposal facility. A selection of irradiated graphite samples from Oldbury reactor one were examined where it was observed that Raman spectroscopy can distinguish between underlying graphite and a surface deposit found on exposed channel wall surfaces. The concentration of 14C in this deposit was examined by sequentially oxidising the graphite samples in air at low temperatures (450°C and 600°C) to remove the deposit and then the underlying graphite. The gases produced were captured in a series of bubbler solutions that were analysed using liquid scintillation counting. It was observed that the surface deposit was relatively enriched with 14C, with samples originating lower in the reactor exhibiting a higher concentration of 14C. Oxidation at 600°C showed that the remaining graphite material consisted of two fractions of 14C, a surface associated fraction and a graphite lattice associated fraction. The results presented correlate well with previous studies on irradiated graphite that suggest there are up to three fractions of 14C; a readily releasable fraction (corresponding to that removed by oxidation at 450°C in this study), a slowly releasable fraction (removed early at 600°C in this study), and an unreleasable fraction (removed later at 600°C in this study).

  10. Examination of Surface Deposits on Oldbury Reactor Core Graphite to Determine the Concentration and Distribution of 14C

    PubMed Central

    Payne, Liam; Heard, Peter J.; Scott, Thomas B.

    2016-01-01

    Pile Grade A graphite was used as a moderator and reflector material in the first generation of UK Magnox nuclear power reactors. As all of these reactors are now shut down there is a need to examine the concentration and distribution of long lived radioisotopes, such as 14C, to aid in understanding their behaviour in a geological disposal facility. A selection of irradiated graphite samples from Oldbury reactor one were examined where it was observed that Raman spectroscopy can distinguish between underlying graphite and a surface deposit found on exposed channel wall surfaces. The concentration of 14C in this deposit was examined by sequentially oxidising the graphite samples in air at low temperatures (450°C and 600°C) to remove the deposit and then the underlying graphite. The gases produced were captured in a series of bubbler solutions that were analysed using liquid scintillation counting. It was observed that the surface deposit was relatively enriched with 14C, with samples originating lower in the reactor exhibiting a higher concentration of 14C. Oxidation at 600°C showed that the remaining graphite material consisted of two fractions of 14C, a surface associated fraction and a graphite lattice associated fraction. The results presented correlate well with previous studies on irradiated graphite that suggest there are up to three fractions of 14C; a readily releasable fraction (corresponding to that removed by oxidation at 450°C in this study), a slowly releasable fraction (removed early at 600°C in this study), and an unreleasable fraction (removed later at 600°C in this study). PMID:27706228

  11. Posttest data analysis of FIST experimental TRAC-BD1/MOD1 power transient experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wheatley, P.D.; Wagner, K.C.

    The FIST power transient test 6PMC2 was analyzed to further the understanding of the FIST facility and provide an assessment of TRAC-BD1/MOD1. FIST power transient 6PMC2 investigated the thermal-hydraulic response following inadvertent closure of the main steam isolation valve and the subsequent failure of the reactor to scram. Failure of the high pressure core spray system was also assumed, resulting in only the reactor core isolation cooling flow for inventory makeup during the transient. The experiment was a sensitivity study with relatively high core power and low makeup rates. This study provides one of the first opportunities to assess TRAC-BD1/MOD1more » under power transient and natural circulation conditions with data from a facility with prototypical BWR geometry. The power transient test was analyzed with emphasis on the following phenomena: (a) the system pressure response, (b) the natural circulation flows and rates, and (c) the heater rod cladding temperature response. Based on the results of this study, TRAC-BD1/MOD1 can be expected to calculate the thermal-hydraulic behavior of a BWR during a power transient.« less

  12. NAD(P)H:quinone oxidoreductase 1 (NQO1) competes with 20S proteasome for binding with C/EBPα leading to its stabilization and protection against radiation-induced myeloproliferative disease.

    PubMed

    Xu, Junkang; Jaiswal, Anil K

    2012-12-07

    NAD(P)H:quinone oxidoreductase 1 (NQO1) is a flavoprotein that protects cells against radiation and chemical-induced oxidative stress. Disruption of NQO1 gene in mice leads to increased susceptibility to myeloproliferative disease. In this report, we demonstrate that NQO1 controls the stability of myeloid differentiation factor C/EBPα against 20S proteasomal degradation during radiation exposure stress. Co-immunoprecipitation studies showed that NQO1, C/EBPα, and 20S all interacted with each other. C/EBPα interaction with 20S led to the degradation of C/EBPα. NQO1 in presence of its cofactor NADH protected C/EBPα against 20S degradation. Deletion and site-directed mutagenesis demonstrated that NQO1 and 20S competed for the same binding region (268)SGAGAGKAKKSV(279) in C/EBPα. Mutagenesis studies also revealed that NQO1Y127/Y129 required for NADH binding is essential for NQO1 stabilization of C/EBPα. Exposure of mice and HL-60 cells to 3 Grays of γ-radiation led to increased NQO1 that stabilized C/EBPα against 20S proteasomal degradation. This mechanism of NQO1 regulation of C/EBPα may provide protection to bone marrow against adverse effects of radiation exposure. The studies have significance for human individuals carrying hetero- or homozygous NQO1P187S mutation and are deficient or lack NQO1 protein.

  13. Grumman S2F-1 Tracker at NACA Lewis

    NASA Image and Video Library

    1956-08-21

    The NACA’s Lewis Flight Propulsion Laboratory acquired the Grumman S2F-1 Tracker from the Navy in 1955 to study icing instrumentation. Lewis’s icing research program was winding down at the time. The use of jet engines was increasing thus reducing the threat of ice accumulation. Nonetheless Lewis continued research on the instrumentation used to detect icing conditions. The S2F-1 Tracker was a carrier-based submarine hunter for the Navy. Grumman developed the Tracker as a successor to its Korean War-era Guardian patrol aircraft. Prototypes first flew in late 1952 and battle-ready versions entered Naval service in early 1954. The Navy utilized the Trackers to protect fleets from attack.

  14. U.S. Department of Energy Accident Resistant SiC Clad Nuclear Fuel Development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    George W. Griffith

    2011-10-01

    A significant effort is being placed on silicon carbide ceramic matrix composite (SiC CMC) nuclear fuel cladding by Light Water Reactor Sustainability (LWRS) Advanced Light Water Reactor Nuclear Fuels Pathway. The intent of this work is to invest in a high-risk, high-reward technology that can be introduced in a relatively short time. The LWRS goal is to demonstrate successful advanced fuels technology that suitable for commercial development to support nuclear relicensing. Ceramic matrix composites are an established non-nuclear technology that utilizes ceramic fibers embedded in a ceramic matrix. A thin interfacial layer between the fibers and the matrix allows formore » ductile behavior. The SiC CMC has relatively high strength at high reactor accident temperatures when compared to metallic cladding. SiC also has a very low chemical reactivity and doesn't react exothermically with the reactor cooling water. The radiation behavior of SiC has also been studied extensively as structural fusion system components. The SiC CMC technology is in the early stages of development and will need to mature before confidence in the developed designs can created. The advanced SiC CMC materials do offer the potential for greatly improved safety because of their high temperature strength, chemical stability and reduced hydrogen generation.« less

  15. Power Balance Analysis of the Prototype-Material Plasma Exposure eXperiment

    NASA Astrophysics Data System (ADS)

    Showers, M. A.; Biewer, T. M.; Caneses, J. F.; Caughman, J. B. O.; Lumsdaine, A.; Owen, L.; Rapp, J.; Youchison, D.; Beers, C. J.; Donovan, D. C.; Kafle, N.; Ray, H. B.

    2017-10-01

    The Prototype-Material Plasma Exposure eXperiment (Proto-MPEX) is a test bed for the plasma source concept for the planned Material Plasma Exposure eXperiment (MPEX), a steady-state linear device studying plasma material interactions for fusion reactors. A power balance of Proto-MPEX attempts to identify machine operating parameters that will improve Proto-MPEX's performance, potentially impacting the MPEX design concept. A power balance has been performed utilizing an extensive diagnostic suite to identify mechanisms and locations of power loss from the main plasma. The diagnostic package includes infrared cameras, double Langmuir probes, fluoroptic probes, Mach probes, a Thomson scattering diagnostic, a McPherson spectrometer and in-vessel thermocouples. Radiation losses are estimated with absolute calibrated spectroscopic signals. This work was supported by the U.S. D.O.E. contract DE-AC05-00OR22725.

  16. The Chip-Scale Atomic Clock - Prototype Evaluation

    DTIC Science & Technology

    2007-11-01

    39th Annual Precise Time and Time Interval (PTTI) Meeting THE CHIP-SCALE ATOMIC CLOCK – PROTOTYPE EVALUATION R. Lutwak *, A. Rashed...been supported by the Defense Advanced Research Projects Agency, Contract # NBCHC020050. REFERENCES [1] R. Lutwak , D. Emmons, W. Riley, and...D.C.), pp. 539-550. [2] R. Lutwak , D. Emmons, T. English, W. Riley, A. Duwel, M. Varghese, D. K. Serkland, and G. M. Peake, 2004, “The Chip-Scale

  17. Optical memory development. Volume 1: prototype memory system

    NASA Technical Reports Server (NTRS)

    Cosentino, L. S.; Mezrich, R. S.; Nagle, E. M.; Stewart, W. C.; Wendt, F. S.

    1972-01-01

    The design, development, and implementation of a prototype, partially populated, million bit read-write holographic memory system using state-of-the-art components are described. The system employs an argon ion laser, acoustooptic beam deflectors, a holographic beam splitter (hololens), a nematic liquid crystal page composer, a photoconductor-thermoplastic erasable storage medium, a silicon P-I-N photodiode array, with lenses and electronics of both conventional and custom design. Operation of the prototype memory system was successfully demonstrated. Careful attention is given to the analysis from which the design criteria were developed. Specifications for the major components are listed, along with the details of their construction and performance. The primary conclusion resulting from this program is that the basic principles of read-write holographic memory system are well understood and are reducible to practice.

  18. New Ωc0 baryons discovered by LHCb as the members of 1 P and 2 S states

    NASA Astrophysics Data System (ADS)

    Chen, Bing; Liu, Xiang

    2017-11-01

    Inspired by the recently observed Ωc0 states at LHCb, we decode their properties by performing an analysis of their mass spectrum and decay behavior. Our studies show that the five narrow states, i.e., Ωc(3000 )0, Ωc(3050 )0, Ωc(3066 )0, Ωc(3090 )0, and Ωc(3119 )0, could be grouped into the 1 P states with negative parity. Among them, the Ωc(3000 )0 and Ωc(3090 )0 states could be the JP=1 /2- candidates, while Ωc(3050 )0 and Ωc(3119 )0 are suggested as the JP=3 /2- states. Ωc(3066 )0 could be regarded as a JP=5 /2- state. Since the spin-parity, electromagnetic transitions, and possible hadronic decay channels Ωc(*)π have not been measured yet, other explanations are also probable for these narrow Ωc0 states. Additionally, we discuss the possibility of the broad structure Ωc(3188 )0 as a 2 S state with JP=1 /2+ or JP=3 /2+. In our scheme, Ωc(3119 )0 cannot be a 2 S candidate.

  19. 75 FR 3501 - Advisory Committee on Reactor Safeguards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards In accordance with the purposes of Sections 29 and 182b of the Atomic Energy Act (42 U.S.C. 2039, 2232b), the Advisory Committee on Reactor Safeguards (ACRS) will hold a meeting on February 4-6, 2010, 11545 Rockville Pike...

  20. Prototype Systems for Measuring Outdoor Air Intake Rates in Rooftop Air Handlers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fisk, William J.; Chan, Wanyu R.; Hotchi, Toshifumi

    2015-01-01

    The widespread absence of systems for real-time measurement and feedback control, of minimum outdoor air intake rates in HVAC systems contributes to the poor control of ventilation rates in commercial buildings. Ventilation rates affect building energy consumption and influence occupant health. The project designed fabricated and tested four prototypes of systems for measuring rates of outdoor air intake into roof top air handlers. All prototypes met the ±20% accuracy target at low wind speeds, with all prototypes accurate within approximately ±10% after application of calibration equations. One prototype met the accuracy target without a calibration. With two of four prototypemore » measurement systems, there was no evidence that wind speed or direction affected accuracy; however, winds speeds were generally below usually 3.5 m s -1 (12.6 km h -1) and further testing is desirable. The airflow resistance of the prototypes was generally less than 35 Pa at maximum RTU air flow rates. A pressure drop of this magnitude will increase fan energy consumption by approximately 4%. The project did not have resources necessary to estimate costs of mass produced systems. The retail cost of components and materials used to construct prototypes ranged from approximately $1,200 to $1,700. The test data indicate that the basic designs developed in this project, particularly the designs of two of the prototypes, have considerable merit. Further design refinement, testing, and cost analysis would be necessary to fully assess commercial potential. The designs and test results will be communicated to the HVAC manufacturing community.« less

  1. Cold Trap Dismantling and Sodium Removal at a Fast Breeder Reactor - 12327

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Graf, A.; Petrick, H.; Stutz, U.

    2012-07-01

    The first German prototype Fast Breeder Nuclear Reactor (KNK) is currently being dismantled after being the only operating Fast Breeder-type reactor in Germany. As this reactor type used sodium as a coolant in its primary and secondary circuit, seven cold traps containing various amounts of partially activated sodium needed to be disposed of as part of the dismantling. The resulting combined difficulties of radioactive contamination and high chemical reactivity were handled by treating the cold traps differently depending on their size and the amount of sodium contained inside. Six small cold traps were processed onsite by cutting them up intomore » small parts using a band saw under a protective atmosphere. The sodium was then converted to sodium hydroxide by using water. The remaining large cold trap could not be handled in the same way due to its dimensions (2.9 m x 1.1 m) and the declared amount of sodium inside (1,700 kg). It was therefore manually dismantled inside a large box filled with a protective atmosphere, while the resulting pieces were packaged for later burning in a special facility. The experiences gained by KNK during this process may be advantageous for future dismantling projects in similar sodium-cooled reactors worldwide. The dismantling of a prototype fast breeder reactor provides the challenge not only to dismantle radioactive materials but also to handle sodium-contaminated or sodium-containing components. The treatment of sodium requires additional equipment and installations to ensure a safe handling. Since it is not permitted to bring sodium into a repository, all sodium has to be neutralized either through a controlled reaction with water or by incinerating. The resulting components can be disposed of as normal radioactive waste with no further conditions. The handling of sodium needs skilled and experienced workers to minimize the inherent risks. And the example of the disposal of the large KNK cold trap shows the interaction with

  2. Installation package - SIMS prototype system 1A

    NASA Technical Reports Server (NTRS)

    1976-01-01

    This report consists of details for the installation, operation and maintenance of a prototype heating and hot water system, designed for residential or light commercial applications. This system consists of the following subsystems: air type collectors, pebble bed thermal storage, air handling unit, air to water heat exchanger, hot water preheat tank, auxiliary energy, ducting system.

  3. Expanded Owens Valley Solar Array (EOVSA) Testbed and Prototype

    NASA Astrophysics Data System (ADS)

    Gary, Dale E.; Nita, G. M.; Sane, N.

    2012-05-01

    NJIT is engaged in constructing a new solar-dedicated radio array, the Expanded Owens Valley Solar Array (EOVSA), which is slated for completion in late 2013. An initial 3-antenna array, the EOVSA Subsystem Testbed (EST), is now in operation from 1-9 GHz based on three of the old OVSA antennas, to test certain design elements of the new array. We describe this instrument and show some results from recent solar flares observed with it. We also describe plans for an upcoming prototype of EOVSA, which will use three antennas of the new design over the full 1-18 GHz signal chain of the entirely new system. The EOVSA prototype will be in operation by late 2012. Highlights of the new design are ability to cover the entire 1-18 GHz in less than 1 s, simultaneous dual polarization, and improved sensitivity and stability. We discuss what can be expected from the prototype, and how it will compare with the full 13-antenna EOVSA. This work was supported by NSF grants AGS-0961867 and AST-0908344, and NASA grant NNX11AB49G to New Jersey Institute of Technology.

  4. 51. Photocopy of Title Sheet, Booklet of General Plans, U.S.C.G.C ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    51. Photocopy of Title Sheet, Booklet of General Plans, U.S.C.G.C White Heath, WLM-545, U.S. Coast Guard Naval Engineering Department, U.S.C.G. Headquarters, Washington, D.C. Coast Guard Headquarters Drawing No. 540-WAGL-0103-019 C. sheet 1 of 7, dated May 1967; revised June 1971, December 1976, and April 1989. Original drawing property of the U.S. Coast Guard. - U.S. Coast Guard Cutter WHITE HEATH, USGS Integrated Support Command Boston, 427 Commercial Street, Boston, Suffolk County, MA

  5. 76 FR 16458 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR); Notice of Meeting The ACRS Subcommittee on U.S. EPR... of the Safety Evaluation Report (SER) with open items associated with U.S. EPR Design Control...

  6. ``Sleeping reactor`` irradiations: Shutdown reactor determination of short-lived activation products

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jerde, E.A.; Glasgow, D.C.

    1998-09-01

    At the High-Flux Isotope Reactor (HFIR) at the Oak Ridge National Laboratory, the principal irradiation system has a thermal neutron flux ({phi}) of {approximately} 4 {times} 10{sup 14} n/cm{sup 2} {center_dot} s, permitting the detection of elements via irradiation of 60 s or less. Irradiations of 6 or 7 s are acceptable for detection of elements with half-lives of as little as 30 min. However, important elements such as Al, Mg, Ti, and V have half-lives of only a few minutes. At HFIR, these can be determined with irradiation times of {approximately} 6 s, but the requirement of immediate countingmore » leads to increased exposure to the high activity produced by irradiation in the high flux. In addition, pneumatic system timing uncertainties (about {+-} 0.5 s) make irradiations of < 6 s less reliable. Therefore, the determination of these ultra-short-lived species in mixed matrices has not generally been made at HFIR. The authors have found that very short lived activation products can be produced easily during the period after reactor shutdown (SCRAM), but prior to the removal of spent fuel elements. During this 24- to 36-h period (dubbed the ``sleeping reactor``), neutrons are produced in the beryllium reflector by the reaction {sup 9}Be({gamma},n){sup 8}Be, the gamma rays principally originating in the spent fuel. Upon reactor SCRAM, the flux drops to {approximately} 1 {times} 10{sup 10} n/cm{sup 2} {center_dot} s within 1 h. By the time the fuel elements are removed, the flux has dropped to {approximately} 6 {times} 10{sup 8}. Such fluxes are ideal for the determination of short-lived elements such as Al, Ti, Mg, and V. An important feature of the sleeping reactor is a flux that is not constant.« less

  7. 76 FR 22935 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-25

    ... Power Reactor (U.S. EPR) will hold a meeting on May 11, 2011, Room T-2B1, 11545 Rockville Pike.... EPR Design Control Document (DCD). The Subcommittee will hear presentations by and hold discussions...

  8. 10 CFR Appendix A to Part 52 - Design Certification Rule for the U.S. Advanced Boiling Water Reactor

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Water Reactor A Appendix A to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES... Rule for the U.S. Advanced Boiling Water Reactor I. Introduction Appendix A constitutes the standard design certification for the U.S. Advanced Boiling Water Reactor (ABWR) design, in accordance with 10 CFR...

  9. 10 CFR Appendix A to Part 52 - Design Certification Rule for the U.S. Advanced Boiling Water Reactor

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Water Reactor A Appendix A to Part 52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES... Rule for the U.S. Advanced Boiling Water Reactor I. Introduction Appendix A constitutes the standard design certification for the U.S. Advanced Boiling Water Reactor (ABWR) design, in accordance with 10 CFR...

  10. c-Abl phosphorylation of Yin Yang 1's conserved tyrosine 254 in the spacer region modulates its transcriptional activity.

    PubMed

    Daraiseh, Susan I; Kassardjian, Ari; Alexander, Karen E; Rizkallah, Raed; Hurt, Myra M

    2018-05-25

    Yin Yang 1 (YY1) is a multifunctional transcription factor that can activate or repress transcription depending on the promotor and/or the co-factors recruited. YY1 is phosphorylated in various signaling pathways and is critical for different biological functions including embryogenesis, apoptosis, proliferation, cell-cycle regulation and tumorigenesis. Here we report that YY1 is a substrate for c-Abl kinase phosphorylation at conserved residue Y254 in the spacer region. Pharmacological inhibition of c-Abl kinase by imatinib, nilotinib and GZD824, knock-down of c-Abl using siRNA, and the use of c-Abl kinase-dead drastically reduces tyrosine phosphorylation of YY1. Both radioactive and non-radioactive in vitro kinase assays, as well as co-immunoprecipitation in different cell lines, show that the target of c-Abl phosphorylation is tyrosine residue 254. c-Abl phosphorylation has little effect on YY1 DNA binding ability or cellular localization in asynchronous cells. However, functional studies reveal that c-Abl mediated phosphorylation of YY1 regulates YY1's transcriptional ability in vivo. In conclusion, we demonstrate the novel role of c-Abl kinase in regulation of YY1's transcriptional activity, linking YY1 regulation with c-Abl tyrosine kinase signaling pathways. Copyright © 2018. Published by Elsevier B.V.

  11. A prototype experiment for cooperative monitoring of nuclear reactors with cubic meter scale antineutrino detectors

    NASA Astrophysics Data System (ADS)

    Bernstein, A.; Allen, M.; Bowden, N.; Brennan, J.; Carr, D. J.; Estrada, J.; Hagmann, C.; Lund, J. C.; Madden, N. W.; Winant, C. D.

    2005-09-01

    Our Lawrence Livermore National Laboratory/Sandia National Laboratories collaboration has deployed a cubic-meter-scale antineutrino detector to demonstrate non-intrusive and automatic monitoring of the power levels and plutonium content of a nuclear reactor. Reactor monitoring of this kind is required for all non-nuclear weapons states under the Nuclear Nonproliferation Treaty (NPT), and is implemented by the International Atomic Energy Agency (IAEA). Since the antineutrino count rate and energy spectrum depend on the relative yields of fissioning isotopes in the reactor core, changes in isotopic composition can be observed without ever directly accessing the core. Data from a cubic meter scale antineutrino detector, coupled with the well-understood principles that govern the core's evolution in time, can be used to determine whether the reactor is being operated in an illegitimate way. Our group has deployed a detector at the San Onofre reactor site in California to demonstrate this concept. This paper describes the concept and shows preliminary results from 8 months of operation.

  12. 76 FR 4739 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-26

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR); Notice of Meeting The ACRS Subcommittee on U.S. EPR... 6 and Chapter 15 of the U.S. EPR Safety Evaluation Report (SER) with Open Items. The Subcommittee...

  13. Equipment for neutron measurements at VR-1 Sparrow training reactor.

    PubMed

    Kolros, Antonin; Huml, Ondrej; Kríz, Martin; Kos, Josef

    2010-01-01

    The VR-1 sparrow reactor is an experimental nuclear facility for training, student education and teaching purposes. The sparrow reactor is an educational platform for the basic experiments at the reactor physic and dosimetry. The aim of this article is to describe the new experimental equipment EMK310 features and possibilities for neutron detection by different gas filled detectors at VR-1 reactor. Among the EMK310 equipment typical attributes belong precise set-up, simple control, resistance to electromagnetic interference, high throughput (counting rate), versatility and remote controllability. The methods for non-linearity correction of pulse neutron detection system and reactimeter application are presented. Copyright 2009. Published by Elsevier Ltd.

  14. Ethanol Production from Wet-Exploded Wheat Straw Hydrolysate by Thermophilic Anaerobic Bacterium Thermoanaerobacter BG1L1 in a Continuous Immobilized Reactor

    NASA Astrophysics Data System (ADS)

    Georgieva, Tania I.; Mikkelsen, Marie J.; Ahring, Birgitte K.

    Thermophilic ethanol fermentation of wet-exploded wheat straw hydrolysate was investigated in a continuous immobilized reactor system. The experiments were carried out in a lab-scale fluidized bed reactor (FBR) at 70°C. Undetoxified wheat straw hydrolysate was used (3-12% dry matter), corresponding to sugar mixtures of glucose and xylose ranging from 12 to 41 g/1. The organism, thermophilic anaerobic bacterium Thermoanaerobacter BG1L1, exhibited significant resistance to high levels of acetic acid (up to 10 g/1) and other metabolic inhibitors present in the hydrolysate. Although the hydrolysate was not detoxified, ethanol yield in a range of 0.39-0.42 g/g was obtained. Overall, sugar efficiency to ethanol was 68-76%. The reactor was operated continuously for approximately 143 days, and no contamination was seen without the use of any agent for preventing bacterial infections. The tested microorganism has considerable potential to be a novel candidate for lignocellulose bioconversion into ethanol. The work reported here also demonstrates that the use of FBR configuration might be a viable approach for thermophilic anaerobic ethanol fermentation.

  15. Comparative use of the computer-aided angiography and rapid prototyping technology versus conventional imaging in the management of the Tile C pelvic fractures.

    PubMed

    Li, Baofeng; Chen, Bei; Zhang, Ying; Wang, Xinyu; Wang, Fei; Xia, Hong; Yin, Qingshui

    2016-01-01

    Computed tomography (CT) scan with three-dimensional (3D) reconstruction has been used to evaluate complex fractures in pre-operative planning. In this study, rapid prototyping of a life-size model based on 3D reconstructions including bone and vessel was applied to evaluate the feasibility and prospect of these new technologies in surgical therapy of Tile C pelvic fractures by observing intra- and perioperative outcomes. The authors conducted a retrospective study on a group of 157 consecutive patients with Tile C pelvic fractures. Seventy-six patients were treated with conventional pre-operative preparation (A group) and 81 patients were treated with the help of computer-aided angiography and rapid prototyping technology (B group). Assessment of the two groups considered the following perioperative parameters: length of surgical procedure, intra-operative complications, intra- and postoperative blood loss, postoperative pain, postoperative nausea and vomiting (PONV), length of stay, and type of discharge. The two groups were homogeneous when compared in relation to mean age, sex, body weight, injury severity score, associated injuries and pelvic fracture severity score. Group B was performed in less time (105 ± 19 minutes vs. 122 ± 23 minutes) and blood loss (31.0 ± 8.2 g/L vs. 36.2 ± 7.4 g/L) compared with group A. Patients in group B experienced less pain (2.5 ± 2.3 NRS score vs. 2.8 ± 2.0 NRS score), and PONV affected only 8 % versus 10 % of cases. Times to discharge were shorter (7.8 ± 2.0 days vs. 10.2 ± 3.1 days) in group B, and most of patients were discharged to home. In our study, patients of Tile C pelvic fractures treated with computer-aided angiography and rapid prototyping technology had a better perioperative outcome than patients treated with conventional pre-operative preparation. Further studies are necessary to investigate the advantages in terms of clinical results in the short and long run.

  16. Temporal HbA1c patterns amongst patients with type 2 diabetes referred for specialist care: Data from the S4S-DINGO-Diabetes Informatics Group.

    PubMed

    Lam, Teresa; Hoffman, David M; Cukier, Kimberly; Darnell, David; Greenfield, Jerry R; Harrison, Natalie; Hng, Tien-Ming; Morrow, Anthony F; Cheung, N Wah

    2016-06-01

    To evaluate the achievement of HbA1c targets in patients with type 2 diabetes mellitus in specialist practice. This audit was undertaken by members of the S4S Diabetes Informatics Group (DINGO), a consortium of Australian endocrinologists in private practice who contribute de-identified data from their electronic medical record, Audit 4 (Software 4 Specialists, S4S, Australia & New Zealand) for audit purposes. Data from patients with type 2 diabetes was extracted. Inclusion criteria were: initial age<70years, baseline HbA1c>7% (53mmol/mol), with at least another HbA1c recorded in the next 2years, and a minimum of 2years follow-up. Data was analysed using a linear mixed effects model. Of the 4796 patients in the dataset with type 2 diabetes mellitus, 1379 patients fulfilled inclusion criteria. The median age at initial consultation was 57 (49-64)years. The median baseline HbA1c was 8.7 (7.8-9.8)% (72mmol/mol). There was a 1.0% reduction in HbA1c to 7.7 (7.1-8.6)% (61mmol/mol) (p<0.0001) in the first 3-6months following referral, after which there were no further changes. The initial reduction was maintained with minimal loss of control at 4years. By 3-6months, 24% of patients achieved the target HbA1c. Referral of patients with type 2 diabetes to an endocrinologist reduces HbA1c, and the effect is sustained over the medium term; however only a minority of patients reach targets. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  17. Creation of Prototype Aircrew Protection Equipment Based on Face Anthropometry

    DTIC Science & Technology

    1993-12-01

    AD-A273 865 AFIT/GSE/ENY/93D-2AD 27 86 DTIC ELECTE SDE.C 161993 A : CREATION OF PROTOTYPE AIRCREW PROTECTION EQUIPMENT BASED ON FACE ANTHROPOMETRY ...AIRCREW PROTECTION EQUIPMENT BASED ON FACE ANTHROPOMETRY THESIS Presented to the Faculty of the Graduate School of Engineering of the Air Force Institute...trans- form anthropomorphic surfaces into a prototype mask mold. xix CREATION OF PROTOTYPE AIRCREW PROTECTION EQUIPMENT BASED ON FACE ANTHROPOMETRY L

  18. The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions.

    PubMed

    Hegde, Muralidhar L; Tsutakawa, Susan E; Hegde, Pavana M; Holthauzen, Luis Marcelo F; Li, Jing; Oezguen, Numan; Hilser, Vincent J; Tainer, John A; Mitra, Sankar

    2013-07-10

    NEIL1 [Nei (endonuclease VIII)-like protein 1], one of the five mammalian DNA glycosylases that excise oxidized DNA base lesions in the human genome to initiate base excision repair, contains an intrinsically disordered C-terminal domain (CTD; ~100 residues), not conserved in its Escherichia coli prototype Nei. Although dispensable for NEIL1's lesion excision and AP lyase activities, this segment is required for efficient in vivo enzymatic activity and may provide an interaction interface for many of NEIL1's interactions with other base excision repair proteins. Here, we show that the CTD interacts with the folded domain in native NEIL1 containing 389 residues. The CTD is poised for local folding in an ordered structure that is induced in the purified fragment by osmolytes. Furthermore, deletion of the disordered tail lacking both Tyr and Trp residues causes a red shift in NEIL1's intrinsic Trp-specific fluorescence, indicating a more solvent-exposed environment for the Trp residues in the truncated protein, which also exhibits reduced stability compared to the native enzyme. These observations are consistent with stabilization of the native NEIL1 structure via intramolecular, mostly electrostatic, interactions that were disrupted by mutating a positively charged (Lys-rich) cluster of residues (amino acids 355-360) near the C-terminus. Small-angle X-ray scattering (SAXS) analysis confirms the flexibility and dynamic nature of NEIL1's CTD, a feature that may be critical to providing specificity for NEIL1's multiple, functional interactions. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Scram recoveries---C Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Constable, D.W.; Pierce, J.R.; Wood, S.A.

    1962-04-26

    The purpose of this report is to discuss the observations made on two equilibrium scram recovery startups (April 5 and April 16). Normally, the two startups would have little significance but unusual ruptures were experienced in the top near section of the reactor shortly after both startups, which indicates that some similarity could exist between the two. The ruptures were unusual in that the two tubes involved both had multiple ruptures. One tube contained two E{sup 2} ruptures and the other tube contained three overbore metal ruptures. The overbore tube also contained three incipient ruptures (uranium split under the can).more » The initial rise to power on both startups appeared to be normal with the flux peaking on the near side as expected. On the April 16 startup the maximum level reached was 1050 at which time a rupture in overbore tube 3062 caused on increase in pressure resulting in a high trip on the Panellit gauge. A level of 1600 was reached on the April 5 startup which was held for approximately 14 hours at which time the reactor was shut down due to rupture indications on row 29.« less

  20. Kaiser Permanente-Sandia National Health Care Model: Phase 1 prototype final report. Part 2 -- Domain analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Edwards, D.; Yoshimura, A.; Butler, D.

    This report describes the results of a Cooperative Research and Development Agreement between Sandia National Laboratories and Kaiser Permanente Southern California to develop a prototype computer model of Kaiser Permanente`s health care delivery system. As a discrete event simulation, SimHCO models for each of 100,000 patients the progression of disease, individual resource usage, and patient choices in a competitive environment. SimHCO is implemented in the object-oriented programming language C{sup 2}, stressing reusable knowledge and reusable software components. The versioned implementation of SimHCO showed that the object-oriented framework allows the program to grow in complexity in an incremental way. Furthermore, timingmore » calculations showed that SimHCO runs in a reasonable time on typical workstations, and that a second phase model will scale proportionally and run within the system constraints of contemporary computer technology.« less

  1. Monte-Carlo Simulations of the Nuclear Energy Deposition Inside the CARMEN-1P Differential Calorimeter Irradiated into OSIRIS Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Amharrak, H.; Reynard-Carette, C.; Carette, M.

    The nuclear heating measurements in Material Testing Reactors (MTRs) are crucial for the study of nuclear materials and fuels under irradiation. The reference measurements of this nuclear heating are especially performed by a differential calorimeter including a graphite sample material. These measurements are then used for other experimental conditions in order to predict the nuclear heating and thermal conditions induced in the irradiation devices. Nuclear heating is a great deal of interest at the moment as the measurement of such heating is an important issue for MTRs reactors. This need is especially generated by the new Jules Horowitz Reactor (JHR),more » under construction at CEA/Cadarache 'French Alternative Energies and Atomic Energy Commission'. This new reactor, that will be operational in late 2019, is a new facility for the nuclear research on materials and fuels. Indeed the expected nuclear heating rate is about 20 W/g for nominal capacity of 100 MW. The present Monte Carlo calculation works belong to the IN-CORE (Instrumentation for Nuclear radiation and Calorimetry On line in Reactor): a joint research program between the CEA and Aix- Marseille University in 2009. One scientific aim of this program is to design and develop a multi-sensors device, called CARMEN, dedicated to the measurements of main physical parameters simultaneously encountered inside JHR's experimental channels (core and reflector) such as neutron fluxes, photon fluxes, temperature, and nuclear heating. A first prototype was already developed. This prototype includes two mock-ups dedicated respectively to neutronic measurements (CARMEN-1N) and to photonic measurements (CARMEN-1P) with in particular a specific differential calorimeter. Two irradiation campaigns were performed successfully in the periphery of OSIRIS reactor (a MTR located at Saclay, France) in 2012 for nuclear heating levels up to 2 W/g. First Monte Carlo calculations reduced to the graphite sample of the

  2. Rapid prototyping and stereolithography in dentistry

    PubMed Central

    Nayar, Sanjna; Bhuminathan, S.; Bhat, Wasim Manzoor

    2015-01-01

    The word rapid prototyping (RP) was first used in mechanical engineering field in the early 1980s to describe the act of producing a prototype, a unique product, the first product, or a reference model. In the past, prototypes were handmade by sculpting or casting, and their fabrication demanded a long time. Any and every prototype should undergo evaluation, correction of defects, and approval before the beginning of its mass or large scale production. Prototypes may also be used for specific or restricted purposes, in which case they are usually called a preseries model. With the development of information technology, three-dimensional models can be devised and built based on virtual prototypes. Computers can now be used to create accurately detailed projects that can be assessed from different perspectives in a process known as computer aided design (CAD). To materialize virtual objects using CAD, a computer aided manufacture (CAM) process has been developed. To transform a virtual file into a real object, CAM operates using a machine connected to a computer, similar to a printer or peripheral device. In 1987, Brix and Lambrecht used, for the first time, a prototype in health care. It was a three-dimensional model manufactured using a computer numerical control device, a type of machine that was the predecessor of RP. In 1991, human anatomy models produced with a technology called stereolithography were first used in a maxillofacial surgery clinic in Viena. PMID:26015715

  3. Rapid prototyping and stereolithography in dentistry.

    PubMed

    Nayar, Sanjna; Bhuminathan, S; Bhat, Wasim Manzoor

    2015-04-01

    The word rapid prototyping (RP) was first used in mechanical engineering field in the early 1980s to describe the act of producing a prototype, a unique product, the first product, or a reference model. In the past, prototypes were handmade by sculpting or casting, and their fabrication demanded a long time. Any and every prototype should undergo evaluation, correction of defects, and approval before the beginning of its mass or large scale production. Prototypes may also be used for specific or restricted purposes, in which case they are usually called a preseries model. With the development of information technology, three-dimensional models can be devised and built based on virtual prototypes. Computers can now be used to create accurately detailed projects that can be assessed from different perspectives in a process known as computer aided design (CAD). To materialize virtual objects using CAD, a computer aided manufacture (CAM) process has been developed. To transform a virtual file into a real object, CAM operates using a machine connected to a computer, similar to a printer or peripheral device. In 1987, Brix and Lambrecht used, for the first time, a prototype in health care. It was a three-dimensional model manufactured using a computer numerical control device, a type of machine that was the predecessor of RP. In 1991, human anatomy models produced with a technology called stereolithography were first used in a maxillofacial surgery clinic in Viena.

  4. Convective cooling in a pool-type research reactor

    NASA Astrophysics Data System (ADS)

    Sipaun, Susan; Usman, Shoaib

    2016-01-01

    A reactor produces heat arising from fission reactions in the nuclear core. In the Missouri University of Science and Technology research reactor (MSTR), this heat is removed by natural convection where the coolant/moderator is demineralised water. Heat energy is transferred from the core into the coolant, and the heated water eventually evaporates from the open pool surface. A secondary cooling system was installed to actively remove excess heat arising from prolonged reactor operations. The nuclear core consists of uranium silicide aluminium dispersion fuel (U3Si2Al) in the form of rectangular plates. Gaps between the plates allow coolant to pass through and carry away heat. A study was carried out to map out heat flow as well as to predict the system's performance via STAR-CCM+ simulation. The core was approximated as porous media with porosity of 0.7027. The reactor is rated 200kW and total heat density is approximately 1.07+E7 Wm-3. An MSTR model consisting of 20% of MSTR's nuclear core in a third of the reactor pool was developed. At 35% pump capacity, the simulation results for the MSTR model showed that water is drawn out of the pool at a rate 1.28 kg s-1 from the 4" pipe, and predicted pool surface temperature not exceeding 30°C.

  5. Pebble Bed Reactors Design Optimization Methods and their Application to the Pebble Bed Fluoride Salt Cooled High Temperature Reactor (PB-FHR)

    NASA Astrophysics Data System (ADS)

    Cisneros, Anselmo Tomas, Jr.

    The Fluoride salt cooled High temperature Reactor (FHR) is a class of advanced nuclear reactors that combine the robust coated particle fuel form from high temperature gas cooled reactors, direct reactor auxillary cooling system (DRACS) passive decay removal of liquid metal fast reactors, and the transparent, high volumetric heat capacitance liquid fluoride salt working fluids---flibe (33%7Li2F-67%BeF)---from molten salt reactors. This combination of fuel and coolant enables FHRs to operate in a high-temperature low-pressure design space that has beneficial safety and economic implications. In 2012, UC Berkeley was charged with developing a pre-conceptual design of a commercial prototype FHR---the Pebble Bed- Fluoride Salt Cooled High Temperature Reactor (PB-FHR)---as part of the Nuclear Energy University Programs' (NEUP) integrated research project. The Mark 1 design of the PB-FHR (Mk1 PB-FHR) is 236 MWt flibe cooled pebble bed nuclear heat source that drives an open-air Brayton combine-cycle power conversion system. The PB-FHR's pebble bed consists of a 19.8% enriched uranium fuel core surrounded by an inert graphite pebble reflector that shields the outer solid graphite reflector, core barrel and reactor vessel. The fuel reaches an average burnup of 178000 MWt-d/MT. The Mk1 PB-FHR exhibits strong negative temperature reactivity feedback from the fuel, graphite moderator and the flibe coolant but a small positive temperature reactivity feedback of the inner reflector and from the outer graphite pebble reflector. A novel neutronics and depletion methodology---the multiple burnup state methodology was developed for an accurate and efficient search for the equilibrium composition of an arbitrary continuously refueled pebble bed reactor core. The Burnup Equilibrium Analysis Utility (BEAU) computer program was developed to implement this methodology. BEAU was successfully benchmarked against published results generated with existing equilibrium depletion codes VSOP

  6. SCW Pressure-Channel Nuclear Reactor Some Design Features

    NASA Astrophysics Data System (ADS)

    Pioro, Igor L.; Khan, Mosin; Hopps, Victory; Jacobs, Chris; Patkunam, Ruban; Gopaul, Sandeep; Bakan, Kurtulus

    Concepts of nuclear reactors cooled with water at supercritical pressures were studied as early as the 1950s and 1960s in the USA and Russia. After a 30-year break, the idea of developing nuclear reactors cooled with SuperCritical Water (SCW) became attractive again as the ultimate development path for water cooling. The main objectives of using SCW in nuclear reactors are: 1) to increase the thermal efficiency of modern Nuclear Power Plants (NPPs) from 30-35% to about 45-48%, and 2) to decrease capital and operational costs and hence decrease electrical energy costs (˜1000 US/kW or even less). SCW NPPs will have much higher operating parameters compared to modern NPPs (pressure about 25 MPa and outlet temperature up to 625°C), and a simplified flow circuit, in which steam generators, steam dryers, steam separators, etc., can be eliminated. Also, higher SCW temperatures allow direct thermo-chemical production of hydrogen at low cost, due to increased reaction rates. Pressure-tube or pressure-channel SCW nuclear reactor concepts are being developed in Canada and Russia for some time. Some design features of the Canadian concept related to fuel channels are discussed in this paper. The main conclusion is that the development of SCW pressure-tube nuclear reactors is feasible and significant benefits can be expected over other thermal-energy systems.

  7. Observation of e+e-→ω χc 1 ,2 near √{s }=4.42 and 4.6 GeV

    NASA Astrophysics Data System (ADS)

    Ablikim, M.; Achasov, M. N.; Ai, X. C.; Albayrak, O.; Albrecht, M.; Ambrose, D. J.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Baldini Ferroli, R.; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, H. Y.; Chen, J. C.; Chen, M. L.; Chen, S. J.; Chen, X.; Chen, X. R.; Chen, Y. B.; Cheng, H. P.; Chu, X. K.; Cibinetto, G.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; de Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Dou, Z. L.; Du, S. X.; Duan, P. F.; Eren, E. E.; Fan, J. Z.; Fang, J.; Fang, S. S.; Fang, X.; Fang, Y.; Farinelli, R.; Fava, L.; Fedorov, O.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. L.; Gao, X. Y.; Gao, Y.; Gao, Z.; Garzia, I.; Goetzen, K.; Gong, L.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guan, Y. H.; Guo, A. Q.; Guo, L. B.; Guo, Y.; Guo, Y. P.; Haddadi, Z.; Hafner, A.; Han, S.; Hao, X. Q.; Harris, F. A.; He, K. L.; Held, T.; Heng, Y. K.; Hou, Z. L.; Hu, C.; Hu, H. M.; Hu, J. F.; Hu, T.; Hu, Y.; Huang, G. S.; Huang, J. S.; Huang, X. T.; Huang, Y.; Hussain, T.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. W.; Jiang, X. S.; Jiang, X. Y.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Kiese, P.; Kliemt, R.; Kloss, B.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kuehn, W.; Kupsc, A.; Lange, J. S.; Lara, M.; Larin, P.; Leng, C.; Li, C.; Li, C. H.; Li, Cheng; Li, D. M.; Li, F.; Li, F. Y.; Li, G.; Li, H. B.; Li, J. C.; Li, Jin; Li, K.; Li, K.; Li, Lei; Li, P. R.; Li, Q. Y.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. M.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B. J.; Liu, C. X.; Liu, D.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. H.; Liu, H. H.; Liu, H. M.; Liu, J.; Liu, J. B.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqing; Loehner, H.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, Q. M.; Ma, T.; Ma, X. N.; Ma, X. Y.; Ma, Y. M.; Maas, F. E.; Maggiora, M.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Messchendorp, J. G.; Min, J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales Morales, C.; Muchnoi, N. Yu.; Muramatsu, H.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pan, Y.; Patteri, P.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Poling, R.; Prasad, V.; Qi, H. R.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, L. Q.; Qin, N.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Ripka, M.; Rong, G.; Rosner, Ch.; Ruan, X. D.; Santoro, V.; Sarantsev, A.; Savrié, M.; Schoenning, K.; Schumann, S.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Song, W. M.; Song, X. Y.; Sosio, S.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, X.; Tapan, I.; Thorndike, E. H.; Tiemens, M.; Ullrich, M.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, D.; Wang, D. Y.; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, S. G.; Wang, W.; Wang, W. P.; Wang, X. F.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. H.; Wang, Z. Y.; Weber, T.; Wei, D. H.; Wei, J. B.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, Z.; Xia, L.; Xia, L. G.; Xia, Y.; Xiao, D.; Xiao, H.; Xiao, Z. J.; Xie, Y. G.; Xiu, Q. L.; Xu, G. F.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. J.; Yang, H. X.; Yang, L.; Yang, Y. X.; Ye, M.; Ye, M. H.; Yin, J. H.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, W. L.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zallo, A.; Zeng, Y.; Zeng, Z.; Zhang, B. X.; Zhang, B. Y.; Zhang, C.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J. J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, X. Y.; Zhang, Y.; Zhang, Y. H.; Zhang, Y. N.; Zhang, Y. T.; Zhang, Yu; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, Q. W.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, S. H.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zotti, L.; Zou, B. S.; Zou, J. H.; Besiii Collaboration

    2016-01-01

    Based on data samples collected with the BESIII detector operating at the BEPCII storage ring at center-of-mass energies √{s }>4.4 GeV , the processes e+e-→ω χc 1 ,2 are observed for the first time. With an integrated luminosity of 1074 pb-1 near √{s }=4.42 GeV , a significant ω χc 2 signal is found, and the cross section is measured to be (20.9 ±3.2 ±2.5 ) pb . With 567 pb-1 near √{s }=4.6 GeV , a clear ω χc 1 signal is seen, and the cross section is measured to be (9.5 ±2.1 ±1.3 ) pb , while evidence is found for an ω χc 2 signal. The first errors are statistical, and the second are systematic. Due to low luminosity or low cross section at other energies, no significant signals are observed. In the ω χc 2 cross section, an enhancement is seen around √{s }=4.42 GeV . Fitting the cross section with a coherent sum of the ψ (4415 ) Breit-Wigner function and a phase-space term, the branching fraction B (ψ (4415 )→ω χc 2) is obtained to be of the order of 1 0-3.

  8. M2-F1 in flight being towed by a C-47

    NASA Technical Reports Server (NTRS)

    1964-01-01

    The M2-F1 Lifting Body is seen here being towed behind a C-47 at the Flight Research Center (later redesignated the Dryden Flight Research Center), Edwards, California. In this rear view, the M2-F1 is flying above and to one side of the C-47. This was done to avoid wake turbulence from the towplane. Lacking wings, the M2-F1 used an unusual configuration for its control surfaces. It had two rudders on the fins, two elevons (called 'elephant ears') mounted on the outsides of the fins, and two body flaps on the upper rear fuselage. The wingless, lifting body aircraft design was initially concieved as a means of landing an aircraft horizontally after atmospheric reentry. The absence of wings would make the extreme heat of re-entry less damaging to the vehicle. In 1962, Dryden management approved a program to build a lightweight, unpowered lifting body as a prototype to flight test the wingless concept. It would look like a 'flying bathtub,' and was designated the M2-F1, the 'M' referring to 'manned' and 'F' referring to 'flight' version. It featured a plywood shell placed over a tubular steel frame crafted at Dryden. Construction was completed in 1963. The first flight tests of the M2-F1 were over Rogers Dry Lake at the end of a tow rope attached to a hopped-up Pontiac convertible driven at speeds up to about 120 mph. These initial tests produced enough flight data about the M2-F1 to proceed with flights behind the C-47 tow plane at greater altitudes. The C-47 took the craft to an altitude of 12,000 where free flights back to Rogers Dry Lake began. Pilot for the first series of flights of the M2-F1 was NASA research pilot Milt Thompson. Typical glide flights with the M2-F1 lasted about two minutes and reached speeds of 110 to l20 mph. More than 400 ground tows and 77 aircraft tow flights were carried out with the M2-F1. The success of Dryden's M2-F1 program led to NASA's development and construction of two heavyweight lifting bodies based on studies at NASA's Ames and

  9. U-PuO2, U-PuC, U-PuN cermet fuel for fast reactor

    NASA Astrophysics Data System (ADS)

    Mishra, Sudhir; Kaity, Santu; Banerjee, Joydipta; Nandi, Chiranjeet; Dey, G. K.; Khan, K. B.

    2018-02-01

    Cermet fuel combines beneficial properties of both ceramic and metal and attracts global interest for research as a candidate fuel for nuclear reactors. In the present study, U matrix PuC/PuN/PuO2 cermet for fast reactor have been fabricated on laboratory scale by the powder metallurgy route. Characterization of the fuel has been carried out using Dilatometer, Differential Thermal analysis (DTA), X-ray diffractometer and Optical microscope. X ray diffraction study of the fuel reveals presence of different phases. The PuN dispersed cermet was observed to have high solidus temperature as compared to PuC and PuO2 dispersed cermet. Swelling was observed in U matrix PuO2 cermet which also showed higher thermal expansion. Among the three cermets studied, U matrix PuC cermet showed maximum thermal conductivity.

  10. 37 CFR 1.75 - Claim(s).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Claim(s). 1.75 Section 1.75... GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions Specification § 1.75 Claim(s). (a.... (35 U.S.C. 6; 15 U.S.C. 1113, 1126) [31 FR 12922, Oct. 4, 1966, as amended at 36 FR 12690, July 3...

  11. Simultaneous Synchrotron WAXD and Fast Scanning (Chip) Calorimetry: On the (Isothermal) Crystallization of HDPE and PA11 at High Supercoolings and Cooling Rates up to 200 °C s(-1).

    PubMed

    Baeten, Dorien; Mathot, Vincent B F; Pijpers, Thijs F J; Verkinderen, Olivier; Portale, Giuseppe; Van Puyvelde, Peter; Goderis, Bart

    2015-06-01

    An experimental setup, making use of a Flash DSC 1 prototype, is presented in which materials can be studied simultaneously by fast scanning calorimetry (FSC) and synchrotron wide angle X-ray diffraction (WAXD). Accumulation of multiple, identical measurements results in high quality, millisecond WAXD patterns. Patterns at every degree during the crystallization and melting of high density polyethylene at FSC typical scanning rates from 20 up to 200 °C s(-1) are discussed in terms of the temperature and scanning rate dependent material crystallinities and crystal densities. Interestingly, the combined approach reveals FSC thermal lag issues, for which can be corrected. For polyamide 11, isothermal solidification at high supercooling yields a mesomorphic phase in less than a second, whereas at very low supercooling crystals are obtained. At intermediate supercooling, mixtures of mesomorphic and crystalline material are generated at a ratio proportional to the supercooling. This ratio is constant over the isothermal solidification time. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Reticulated Vitreous Carbon Electrodes for Gas Phase Pulsed Corona Reactors.

    DTIC Science & Technology

    1999-01-01

    AFRL-ML-TY-TP-1999-4546 RETICULATED VITREOUS CARBON ELECTRODES FOR GAS PHASE PULSED CORONA REACTORS B.R. LOCKE M. KIRKPATRICK H. HANSON W.C...SUBTITLE Reticulated Vitreous Carbon Electrodes for Gas Phase Pulsed Corona Reactors 6. AUTHOR(S) B.R. Locke, M. Kirkpatrick, H. Hanson, and W.C. Finney...incorporating reticulated vitreous carbon electrodes is demonstrated to be effective for the removal of nitrogen oxides from synthetic air mixtures

  13. (1S,2E,4S,7E,11E)-2,7,11-Cembratriene-4,6-diol semisynthetic analogs as novel c-Met inhibitors for the control of c-Met-dependent breast malignancies.

    PubMed

    Ebrahim, Hassan Y; Mohyeldin, Mohamed M; Hailat, Mohammad M; El Sayed, Khalid A

    2016-11-15

    (1S,2E,4S,6R,7E,11E)-2,7,11-Cembratriene-4,6-diol (1) and its 4-epi-analog (2) are the cembranoid precursors to several key flavor ingredients in most Nicotiana (tobacco) species. Nearly 40-60% of 1 and 2 are purposely degraded during the commercial tobacco fermentation. However, 1 and 2 display promising bioactivities, including anticancer. Breast cancer is the most diagnosed cancer in women and ranked second female disease killer. The receptor tyrosine kinase c-Met correlates with aggressiveness of certain breast cancer phenotypes and thus considered a valid therapeutic target. This study reports the discovery and optimization of the tobacco-based cembranoid 1 as a novel c-Met inhibitory scaffold using combined structure- and ligand-based approaches. 1 displayed antiproliferative, anti-migratory and anti-invasive effects against the c-Met overexpressing MDA-MB-231 breast cancer cells at moderate μM concentrations. The Z'-LYTE kinase platform and Western blot analysis identified c-Met as a potential macromolecular target. Rationally designed carbamate analogs were proposed to probe additional targeted c-Met interactions and improve the cellular potency. The 6-phenyl carbamate 3 showed enhanced c-Met inhibitory activity. Structure-activity relationships of different substituents on the 3's phenyl moiety were studied. The most active analog 20 showed potent in vitro anticancer activity against the MDA-MB-231 breast cancer cells at low μM concentrations, with minimal toxicity on the non-tumorigenic MCF-10A mammary epithelial cells. Cembranoid 20 potently inhibited the c-Met catalytic activity in Z'-LYTE kinase assay and various cellular c-Met-driven signaling pathways. Furthermore, 20 displayed a robust antitumor activity in a breast cancer xenograft athymic mouse model and thus promoted to the lead rank. Cembranoids are novel c-Met inhibitors appropriate for future use to control c-Met dependent malignancies. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease

    PubMed Central

    1992-01-01

    Serum mannose-binding protein (MBP) is a C-type lectin that binds to terminal mannose and N-acetylglucosamine moieties present on surfaces of certain pathogens and activates the classical complement pathway. In the present study, we describe the mechanism underlying the activation triggered by MBP. The human serum MBP fraction was obtained by sequential affinity chromatography on mannan-Sepharose, anti-IgM- Sepharose and anti-MBP-Sepharose in the presence of calcium ions. This fraction contained a C1s-like serine protease as assessed by C4 consumption. The C1s-like serine protease, designated MBP-associated serine protease (MASP), was separated from MBP by rechromatography on anti-MBP-Sepharose in the presence of ethylenediaminetetraacetic acid. MASP exhibited both C4- and C2-consuming activities. The molecular mass of MASP was estimated to be 83 kD with two polypeptides of heavy (66 kD) and light (L) (31 kD) chains linked by disulfide bonds. The serine residue responsible for protease activity is located on the L chain. Reconstitution experiments using MASP and MBP revealed that combination of the two components restores C4- and C2-activating capacity on mannan. Based on analyses of molecular size, antigenicity, and 11 NH2- terminal amino acid sequences of the L chain, we conclude that MASP is a novel protein different from C1r or C1s. Our findings are not in accord with a proposed mechanism by which MBP utilizes the C1r2-C1s2 complex to initiate the classical complement pathway. PMID:1460414

  15. Magnetic Polarizability of Virtual (s\\bar{s}) and (c\\bar{c}) Pairs in the Nucleon

    NASA Astrophysics Data System (ADS)

    Filip, Peter

    2017-12-01

    We suggest 3 P 0 quantum state of virtual (s\\bar{s}) pairs in the nucleon can be polarised by the internal fields permeating the volume of the nucleon (proton or neutron). Due to the quadratic Zeeman interaction, 3 P 0 wavefunction of virtual (q\\bar{q}) pairs acquires the admixture of 1 P 10 quantum state in the magnetic field, which generates the antiparallel polarization of s and \\bar{s} quarks (in the nucleon). Considering the internal magnetic fields of neutron and proton (originating from their measured magnetic dipole moments), we suggest the induced s-quark polarization in the neutron to be of the oposite direction compared to the proton case. We mention the influence of the internal chromo-magnetic fields on the quantum state of (q\\bar{q}) pairs in the nucleon and we discuss also the expected behaviour of virtual (c\\bar{c}) pairs.

  16. NUCLEAR REACTOR AS THE OBJECT OF CONTROL. AUTOMATIC CONTROL OF AIRCRAFT ENGINES . B.S. Voronkev Collection of Articles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    BS> The dynamics of a power reactor is treated in some detail. Although the reactor is described by a nonlinear differential equation of the seventh order, a two-group approximstion with prompt neutrons and one averaged group of delayed neutrons may be used. When the reactor is in equilibrium, the reactor equation may be linearized in two ways. The effects of positive and negative coefficients of tins of the reactor are discussed. The nonlinear character of the control rods is trested. (D.L.C.)

  17. Implicit face prototype learning from geometric information.

    PubMed

    Or, Charles C-F; Wilson, Hugh R

    2013-04-19

    There is evidence that humans implicitly learn an average or prototype of previously studied faces, as the unseen face prototype is falsely recognized as having been learned (Solso & McCarthy, 1981). Here we investigated the extent and nature of face prototype formation where observers' memory was tested after they studied synthetic faces defined purely in geometric terms in a multidimensional face space. We found a strong prototype effect: The basic results showed that the unseen prototype averaged from the studied faces was falsely identified as learned at a rate of 86.3%, whereas individual studied faces were identified correctly 66.3% of the time and the distractors were incorrectly identified as having been learned only 32.4% of the time. This prototype learning lasted at least 1 week. Face prototype learning occurred even when the studied faces were further from the unseen prototype than the median variation in the population. Prototype memory formation was evident in addition to memory formation of studied face exemplars as demonstrated in our models. Additional studies showed that the prototype effect can be generalized across viewpoints, and head shape and internal features separately contribute to prototype formation. Thus, implicit face prototype extraction in a multidimensional space is a very general aspect of geometric face learning. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. CONTROL IN NUCLEAR REACTORS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bell, F.R.

    1963-01-16

    An arrangement was described for scramming a reactor in an emergency. Control rods were position adjusted by an electric motor and transmission. A locking system kept the control rods in position but was arranged to be released in an emergency to allow the rods to drop into their shutdown position. (C.E.S.)

  19. HIV-1 low copy viral sequencing-A prototype assay.

    PubMed

    Mellberg, Tomas; Krabbe, Jon; Gisslén, Magnus; Svennerholm, Bo

    2016-01-01

    In HIV-1 patients with low viral burden, sequencing is often problematic, yet important. This study presents a sensitive, sub-type independent system for sequencing of low level viremia. Sequencing data from 32 HIV-1 infected patients with low level viremia were collected longitudinally. A combination of ViroSeq® HIV-1 Genotyping System and an in-house nesting protocol was used. Eight sub-types were represented. The success-rate of amplification of both PR and RT in the same sample was 100% in samples with viral loads above 100 copies/ml. Below 100 copies/ml, this study managed to amplify both regions in 7/13 (54%) samples. The assays were able to amplify either PR or RT in all sub-types included but one sub-type A specimen. In conclusion, this study presents a promising, simple assay to increase the ability to perform HIV-1 resistance testing at low level viremia. This is a prototype assay and the method needs further testing to evaluate clinical performance.

  20. Mesophilic and thermophilic biotreatment of BTEX-polluted air in reactors.

    PubMed

    Mohammad, Balsam T; Veiga, María C; Kennes, Christian

    2007-08-15

    This study compares the removal of a mixture of benzene, toluene, ethylbenzene, and all three xylene isomers (BTEX) in mesophilic and thermophilic (50 degrees C) bioreactors. In the mesophilic reactor fungi became dominant after long-term operation, while bacteria dominated in the thermophilic unit. Microbial acclimation was achieved by exposing the biofilters to initial BTEX loads of 2-15 g m(-3) h(-1), at an empty bed residence time of 96 s. After adaptation, the elimination capacities ranged from 3 to 188 g m(-3) h(-1), depending on the inlet load, for the mesophilic biofilter with removal efficiencies reaching 96%. On the other hand, in the thermophilic reactor the average removal efficiency was 83% with a maximum elimination capacity of 218 g m(-3) h(-1). There was a clear positive relationship between temperature gradients as well as CO(2) production and elimination capacities across the biofilters. The gas phase was sampled at different depths along the reactors observing that the percentage pollutant removal in each section was strongly dependant on the load applied. The fate of individual alkylbenzene compounds was checked, showing the unusually high biodegradation rate of benzene at high loads under thermophilic conditions (100%) compared to its very low removal in the mesophilic reactor at such load (<10%). Such difference was less pronounced for the other pollutants. After 210 days of operation, the dry biomass content for the mesophilic and thermophilic reactors were 0.300 and 0.114 g g(-1) (support), respectively, reaching higher removals under thermophilic conditions with a lower biomass accumulation, that is, lower pressure drop. (c) 2007 Wiley Periodicals, Inc.

  1. NASA's Kilopower Reactor Development and the Path to Higher Power Missions

    NASA Technical Reports Server (NTRS)

    Gibson, Marc A.; Oleson, Steven R.; Poston, David I.; McClure, Patrick

    2017-01-01

    The development of NASAs Kilopower fission reactor is taking large strides toward flight development with several successful tests completed during its technology demonstration trials. The Kilopower reactors are designed to provide 1-10 kW of electrical power to a spacecraft which could be used for additional science instruments as well as the ability to power electric propulsion systems. Power rich nuclear missions have been excluded from NASA proposals because of the lack of radioisotope fuel and the absence of a flight qualified fission system. NASA has partnered with the Department of Energy's National Nuclear Security Administration to develop the Kilopower reactor using existing facilities and infrastructure to determine if the design is ready for flight development. The 3-year Kilopower project started in 2015 with a challenging goal of building and testing a full-scale flight prototypic nuclear reactor by the end of 2017. As the date approaches, the engineering team shares information on the progress of the technology as well as the enabling capabilities it provides for science and human exploration.

  2. NASA's Kilopower Reactor Development and the Path to Higher Power Missions

    NASA Technical Reports Server (NTRS)

    Gibson, Marc A.; Oleson, Steven R.; Poston, Dave I.; McClure, Patrick

    2017-01-01

    The development of NASA's Kilopower fission reactor is taking large strides toward flight development with several successful tests completed during its technology demonstration trials. The Kilopower reactors are designed to provide 1-10 kW of electrical power to a spacecraft which could be used for additional science instruments as well as the ability to power electric propulsion systems. Power rich nuclear missions have been excluded from NASA proposals because of the lack of radioisotope fuel and the absence of a flight qualified fission system. NASA has partnered with the Department of Energy's National Nuclear Security Administration to develop the Kilopower reactor using existing facilities and infrastructure to determine if the design is ready for flight development. The 3-year Kilopower project started in 2015 with a challenging goal of building and testing a full-scale flight prototypic nuclear reactor by the end of 2017. As the date approaches, the engineering team shares information on the progress of the technology as well as the enabling capabilities it provides for science and human exploration.

  3. Building on knowledge base of sodium cooled fast spectrum reactors to develop materials technology for fusion reactors

    NASA Astrophysics Data System (ADS)

    Raj, Baldev; Rao, K. Bhanu Sankara

    2009-04-01

    The alloys 316L(N) and Mod. 9Cr-1Mo steel are the major structural materials for fabrication of structural components in sodium cooled fast reactors (SFRs). Various factors influencing the mechanical behaviour of these alloys and different modes of deformation and failure in SFR systems, their analysis and the simulated tests performed on components for assessment of structural integrity and the applicability of RCC-MR code for the design and validation of components are highlighted. The procedures followed for optimal design of die and punch for the near net shape forming of petals of main vessel of 500 MWe prototype fast breeder reactor (PFBR); the safe temperature and strain rate domains established using dynamic materials model for forming of 316L(N) and 9Cr-1Mo steels components by various industrial processes are illustrated. Weldability problems associated with 316L(N) and Mo. 9Cr-1Mo are briefly discussed. The utilization of artificial neural network models for prediction of creep rupture life and delta-ferrite in austenitic stainless steel welds is described. The usage of non-destructive examination techniques in characterization of deformation, fracture and various microstructural features in SFR materials is briefly discussed. Most of the experience gained on SFR systems could be utilized in developing science and technology for fusion reactors. Summary of the current status of knowledge on various aspects of fission and fusion systems with emphasis on cross fertilization of research is presented.

  4. Hybrid C-nanotubes/Si 3D nanostructures by one-step growth in a dual-plasma reactor

    NASA Astrophysics Data System (ADS)

    Toschi, Francesco; Orlanducci, Silvia; Guglielmotti, Valeria; Cianchetta, Ilaria; Magni, Corrado; Terranova, Maria Letizia; Pasquali, Matteo; Tamburri, Emanuela; Matassa, Roberto; Rossi, Marco

    2012-06-01

    Hybrid nanostructures consisting of Si polycrystalline nanocones, with an anemone-like termination coated with C-nanotubes bundles, have been generated on a (1 0 0) Si substrate in a dual mode microwave/radio-frequency plasma reactor. The substrate is both heated and bombarded by energetic H ions during the synthesis process. The nanocones growth is explained considering pull of the growing Si nanocrystalline phase along the lines of the electrical field, likely via a molten/recrystallization mechanism. The one-step building of the achieved complex 3D architectures is described in terms of dynamic competition between Si and C nanotubes growth under the peculiar conditions of kinetically driven processes.

  5. 76 FR 39254 - Airworthiness Directives; Schweizer Aircraft Corporation (Schweizer) Model 269A, A-1, B, C, C-1...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-06

    ... Airworthiness Directives; Schweizer Aircraft Corporation (Schweizer) Model 269A, A-1, B, C, C-1, and TH-55... reviewed Schweizer Service Bulletins No. B-295 for Model 269A, A-1, B, and C helicopters, and No. C1B-032... citation for Part 39 continues to read as follows: Authority: 49 U.S.C. 106(g), 40113, 44701. Sec. 39.13...

  6. Phosphatidylserine Stimulates Ceramide 1-Phosphate (C1P) Intermembrane Transfer by C1P Transfer Proteins.

    PubMed

    Zhai, Xiuhong; Gao, Yong-Guang; Mishra, Shrawan K; Simanshu, Dhirendra K; Boldyrev, Ivan A; Benson, Linda M; Bergen, H Robert; Malinina, Lucy; Mundy, John; Molotkovsky, Julian G; Patel, Dinshaw J; Brown, Rhoderick E

    2017-02-10

    Genetic models for studying localized cell suicide that halt the spread of pathogen infection and immune response activation in plants include Arabidopsis accelerated-cell-death 11 mutant ( acd11 ). In this mutant, sphingolipid homeostasis is disrupted via depletion of ACD11, a lipid transfer protein that is specific for ceramide 1-phosphate (C1P) and phyto-C1P. The C1P binding site in ACD11 and in human ceramide-1-phosphate transfer protein (CPTP) is surrounded by cationic residues. Here, we investigated the functional regulation of ACD11 and CPTP by anionic phosphoglycerides and found that 1-palmitoyl-2-oleoyl-phosphatidic acid or 1-palmitoyl-2-oleoyl-phosphatidylglycerol (≤15 mol %) in C1P source vesicles depressed C1P intermembrane transfer. By contrast, replacement with 1-palmitoyl-2-oleoyl-phosphatidylserine stimulated C1P transfer by ACD11 and CPTP. Notably, "soluble" phosphatidylserine (dihexanoyl-phosphatidylserine) failed to stimulate C1P transfer. Also, none of the anionic phosphoglycerides affected transfer action by human glycolipid lipid transfer protein (GLTP), which is glycolipid-specific and has few cationic residues near its glycolipid binding site. These findings provide the first evidence for a potential phosphoglyceride headgroup-specific regulatory interaction site(s) existing on the surface of any GLTP-fold and delineate new differences between GLTP superfamily members that are specific for C1P versus glycolipid. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  7. Rapid Prototyping of Computer-Based Presentations Using NEAT, Version 1.1.

    ERIC Educational Resources Information Center

    Muldner, Tomasz

    NEAT (iNtegrated Environment for Authoring in ToolBook) provides templates and various facilities for the rapid prototyping of computer-based presentations, a capability that is lacking in current authoring systems. NEAT is a specialized authoring system that can be used by authors who have a limited knowledge of computer systems and no…

  8. Saturn V First Stage (S-1C) Ready for Assembly AT KSC

    NASA Technical Reports Server (NTRS)

    1968-01-01

    This photograph shows the Saturn V first stage (S-1C) in the Vehicle Assembly Building at Kennedy Space Center ready to be mated with the second and third stages to complete the assembly of a Saturn V launch vehicle. This particular Saturn V was used for Apollo 6, which was a systems test flight. The towering 363-foot Saturn V was a multi-stage, multi-engine launch vehicle standing taller than the Statue of Liberty. Altogether, the Saturn V engines produced as much power as 85 Hoover Dams.

  9. A poly-epoxy surface explored by Hartree-Fock ΔSCF simulations of C1s XPS spectra

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gavrielides, A.; Duguet, T., E-mail: thomas.duguet@ensiacet.fr, E-mail: Paul.Bagus@unt.edu; Esvan, J.

    Whereas poly-epoxy polymers represent a class of materials with a wide range of applications, the structural disorder makes them difficult to model. In the present work, we use good experimental model samples in the sense that they are pure, fully polymerized, flat and smooth, defect-free, and suitable for ultrahigh vacuum x-ray photoelectron spectroscopy, XPS, experiments. In parallel, we perform Hartree-Fock, HF, calculations of the binding energies, BEs, of the C1s electrons in a model molecule composed of the two constituents of the poly-epoxy sample. These C1s BEs were determined using the HF ΔSCF method, which is known to yield accuratemore » values, especially for the shifts of the BEs, ΔBEs. We demonstrate the benefits of combining rigorous theory with careful XPS measurements in order to obtain correct assignments of the C1s XPS spectra of the polymer sample. Both the relative binding energies—by the ΔSCF method—and relative intensities—in the sudden approximation, SA, are calculated. It results in an excellent match with the experimental spectra. We are able to identify 9 different chemical environments under the C1s peak, where an exclusively experimental work would have found only 3 contributions. In addition, we observe that some contributions are localized at discrete binding energies, whereas others allow a much wider range because of the variation of their second neighbor bound polarization. Therefore, HF-ΔSCF simulations significantly increase the spectral resolution of XPS and thus offer a new avenue for the exploration of the surface of polymers.« less

  10. Regional groundwater flow model for C, K. L. and P reactor areas, Savannah River Site, Aiken, SC

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Flach, G.P.

    2000-02-11

    A regional groundwater flow model encompassing approximately 100 mi2 surrounding the C, K, L, and P reactor areas has been developed. The reactor flow model is designed to meet the planning objectives outlined in the General Groundwater Strategy for Reactor Area Projects by providing a common framework for analyzing groundwater flow, contaminant migration and remedial alternatives within the Reactor Projects team of the Environmental Restoration Department. The model provides a quantitative understanding of groundwater flow on a regional scale within the near surface aquifers and deeper semi-confined to confined aquifers. The model incorporates historical and current field characterization data upmore » through Spring 1999. Model preprocessing is automated so that future updates and modifications can be performed quickly and efficiently. The CKLP regional reactor model can be used to guide characterization, perform scoping analyses of contaminant transport, and serve as a common base for subsequent finer-scale transport and remedial/feasibility models for each reactor area.« less

  11. Characteristics of laser clad α-Ti/TiC+(Ti,W)C1-x/Ti2SC+TiS composite coatings on TA2 titanium alloy

    NASA Astrophysics Data System (ADS)

    Zhai, Yong-Jie; Liu, Xiu-Bo; Qiao, Shi-Jie; Wang, Ming-Di; Lu, Xiao-Long; Wang, Yong-Guang; Chen, Yao; Ying, Li-Xia

    2017-03-01

    TiC reinforced Ti matrix composite coating with Ti2SC/TiS lubricant phases in-situ synthesized were prepared on TA2 titanium alloy by laser cladding with different powder mixtures: 40%Ti-19.5%TiC-40.5%WS2, 40%Ti-25.2%TiC-34.8%WS2, 40%Ti-29.4%TiC-30.6%WS2 (wt%). The phase compositions, microstructure, microhardness and tribological behaviors and wear mechanisms of coatings were investigated systematically. Results indicate that the main phase compositions of three coatings are all continuous matrix α-Ti, reinforced phases of (Ti,W)C1-x and TiC, lubricant phases of Ti2SC and TiS. The microhardness of the three different coatings are 927.1 HV0.5, 1007.5 HV0.5 and 1052.3 HV0.5, respectively. Compared with the TA2 titanium alloy (approximately 180 HV0.5), the microhardness of coatings have been improved dramatically. The coefficients of friction and the wear rates of those coatings are 0.41 and 30.98×10-5 mm3 N-1 m-1, 0.30 and 18.92×10-5 mm3 N-1 m-1, 0.34 and 15.98×10-5 mm3 N-1 m-1, respectively. Comparatively speaking, the coating fabricated with the powder mixtures of 40%Ti-25.2%TiC-34.8%WS2 presents superior friction reduction and anti-wear properties and the main wear mechanisms of that are slight plastic deformation and adhesive wear.

  12. Synthesis of superior fast charging-discharging nano-LiFePO4/C from nano-FePO4 generated using a confined area impinging jet reactor approach.

    PubMed

    Liu, Xiao-min; Yan, Pen; Xie, Yin-Yin; Yang, Hui; Shen, Xiao-dong; Ma, Zi-Feng

    2013-06-14

    LiFePO4/C nanocomposites with excellent electrochemical performance is synthesized from nano-FePO4, generated by a novel method using a confined area impinging jet reactor (CIJR). When discharged at 80 C (13.6 Ag(-1)), the LiFePO4/C delivers a discharge capacity of 95 mA h g(-1), an energy density of 227 W h kg(-1) and a power density of 34 kW kg(-1).

  13. A Computational Model of Public Support for Insurgency and Terrorism: A Prototype for More-General Social-Science Modeling

    DTIC Science & Technology

    2013-01-01

    PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) RAND...prototype model illustrating concretely a new approach. The prototype model itself should be seen not as a definitive end point, but rather as a...9 1 4 8 1 4 8 1 1 1 1 2 2 1 2 2 2 8 9 2 8 9 3 9 9 2 8 8 2 8 9 2 9 9 1 1 3 1 2 4 1 2 4 xviii A Computational Model of Public Support for Insurgency

  14. Photoionization and ionic dissociation of the C3 H3 NS molecule induced by soft X-ray near the C1s edge.

    PubMed

    Lago, A F; Januário, R D; Cavasso Filho, R L; Simon, M; Dávalos, J Z

    2017-10-01

    Time of flight mass spectrometry, electron-ion coincidence, and ion yield spectroscopy were employed to investigate for the first time the thiazole (C 3 H 3 NS) molecule in the gas phase excited by synchrotron radiation in the soft X-ray domain. Total ion yield (TIY) and photoelectron-photoion coincidence (PEPICO) spectra were recorded as a function of the photon energy in the vicinity of the carbon K edge (C1s). The C1s resonant transitions as well as the core ionization thresholds have been determined from the profile of TIY spectrum, and the features were discussed. The corresponding partial ion yields were determined from the PEPICO spectra for the cation species produced upon the molecular photodissociation. Additional ab initio calculations have also been performed from where relevant structural and electronic configuration parameters were obtained for this molecule. Copyright © 2017 John Wiley & Sons, Ltd.

  15. Reversal of OFI and CHF in Research Reactors Operating at 1 to 50 Bar. Version 1.0

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kalimullah, M.; Olson, A. P.; Dionne, B.

    2014-02-28

    The conditions at which the critical heat flux (CHF) and the heat flux at the onset of Ledinegg flow instability (OFI) are equal, are determined for a coolant channel with uniform heat flux as a function of five independent parameters: the channel exit pressure (P), heated length (Lh) , heated diameter (Dh), inlet temperature (Tin), and mass flux (G). A diagram is made by plotting the mass flux and heat flux at the OFI-CHF intersection (reversal from CHF > OFI to CHF < OFI as G increases) as a function of P (1 to 50 bar), for 36 combinations ofmore » the remaining three parameters (Lh , Dh , Tin): Lh = 0.28, 0.61, 1.18 m; Dh = 3, 4, 6, 8 mm; Tin = 30, 50, 70 °C. The use of the diagram to scope whether a research reactor is OFI-limited (below the curve) or CHF-limited based on the five parameters of its coolant channel is described. Justification for application of the diagram to research reactors with axially non-uniform heat flux is provided. Due to its limitations (uncertainties not included), the diagram cannot replace the detailed thermal-hydraulic analysis required for a reactor safety analysis. In order to make the OFI-CHF intersection diagram, two world-class CHF prediction methods (the Hall-Mudawar correlation and the extended Groeneveld 2006 table) are compared for 216 combinations of the five independent parameters. The two widely used OFI correlations (the Saha- Zuber and the Whittle-Forgan with η = 32.5) are also compared for the same combinations of the five parameters. The extended Groeneveld table and the Whittle-Forgan OFI correlation are selected for use in making the diagram. Using the above five design parameters, a research reactor can be represented by a point on the reversal diagram, and the diagram can be used to scope, without a thermal-hydraulic calculation, whether the OFI will occur before the CHF, or the CHF will occur before the OFI when the reactor power is increased keeping the five parameters fixed.« less

  16. Prototyping for surgical and prosthetic treatment.

    PubMed

    Goiato, Marcelo Coelho; Santos, Murillo Rezende; Pesqueira, Aldiéris Alves; Moreno, Amália; dos Santos, Daniela Micheline; Haddad, Marcela Filié

    2011-05-01

    Techniques of rapid prototyping were introduced in the 1980s in the field of engineering for the fabrication of a solid model based on a computed file. After its introduction in the biomedical field, several applications were raised for the fabrication of models to ease surgical planning and simulation in implantology, neurosurgery, and orthopedics, as well as for the fabrication of maxillofacial prostheses. Hence, the literature has described the evolution of rapid prototyping technique in health care, which allowed easier technique, improved surgical results, and fabrication of maxillofacial prostheses. Accordingly, a literature review on MEDLINE (PubMed) database was conducted using the keywords rapid prototyping, surgical planning, and maxillofacial prostheses and based on articles published from 1981 to 2010. After reading the titles and abstracts of the articles, 50 studies were selected owing to their correlations with the aim of the current study. Several studies show that the prototypes have been used in different dental-medical areas such as maxillofacial and craniofacial surgery; implantology; neurosurgery; orthopedics; scaffolds of ceramic, polymeric, and metallic materials; and fabrication of personalized maxillofacial prostheses. Therefore, prototyping has been an indispensable tool in several studies and helpful for surgical planning and fabrication of prostheses and implants.

  17. A prototype retinal prosthesis for visual stimulation.

    PubMed

    Abu-Faraj, Ziad O; Rjeily, Dany M Abou; Nasreddine, Rayan W; Andari, Majid A; Taok, Habib H

    2007-01-01

    Vision loss has severe impacts on its victims, carrying with it physiological, psychological, social, and economic consequences thereby degrading the quality of life and depriving the individual from performing many of the daily living activities. This article describes the design and development of a prototype retinal prosthesis for visual stimulation. The system consists of a webcam, a notebook computer, and a prototype excitatory circuit. The system is driven by a MATLAB-based custom-built software. Live webcam images are converted to an 8 x 8 mosaic of 256 gray scale shades. Subsequently, electrical impulses are generated by the excitatory circuit in real-time to topographically stimulate the corresponding epiretinal cells. Following their conversion to gray scale, recorded data from the central pixel of the mosaic yielded: 36.24 nC for black, 48.48 nC for red, 55.68 nC for green, 67.68 nC for blue, and 91.92 nC for white. These results correlate well with data reported in the literature. The hallmark of this work is in the potential of partial restoration of sight that would add quality to the life of individuals with vision loss.

  18. The shape of the Sc2(μ2-S) unit trapped in C82: crystallographic, computational, and electrochemical studies of the isomers, Sc2(μ2-S)@C(s)(6)-C82 and Sc2(μ2-S)@C(3v)(8)-C82.

    PubMed

    Mercado, Brandon Q; Chen, Ning; Rodríguez-Fortea, Antonio; Mackey, Mary A; Stevenson, Steven; Echegoyen, Luis; Poblet, Josep M; Olmstead, Marilyn M; Balch, Alan L

    2011-05-04

    Single-crystal X-ray diffraction studies of Sc(2)(μ(2)-S)@C(s)(6)-C(82)·Ni(II)(OEP)·2C(6)H(6) and Sc(2)(μ(2)-S)@C(3v)(8)-C(82)·Ni(II)(OEP)·2C(6)H(6) reveal that both contain fully ordered fullerene cages. The crystallographic data for Sc(2)(μ(2)-S)@C(s)(6)-C(82)·Ni(II)(OEP)·2C(6)H(6) show two remarkable features: the presence of two slightly different cage sites and a fully ordered molecule Sc(2)(μ(2)-S)@C(s)(6)-C(82) in one of these sites. The Sc-S-Sc angles in Sc(2)(μ(2)-S)@C(s)(6)-C(82) (113.84(3)°) and Sc(2)(μ(2)-S)@C(3v)(8)-C(82) differ (97.34(13)°). This is the first case where the nature and structure of the fullerene cage isomer exerts a demonstrable effect on the geometry of the cluster contained within. Computational studies have shown that, among the nine isomers that follow the isolated pentagon rule for C(82), the cage stability changes markedly between 0 and 250 K, but the C(s)(6)-C(82) cage is preferred at temperatures ≥250 °C when using the energies obtained with the free encapsulated model (FEM). However, the C(3v)(8)-C(82) cage is preferred at temperatures ≥250 °C using the energies obtained by rigid rotor-harmonic oscillator (RRHO) approximation. These results corroborate the fact that both cages are observed and likely to trap the Sc(2)(μ(2)-S) cluster, whereas earlier FEM and RRHO calculations predicted only the C(s)(6)-C(82) cage is likely to trap the Sc(2)(μ(2)-O) cluster. We also compare the recently published electrochemistry of the sulfide-containing Sc(2)(μ(2)-S)@C(s)(6)-C(82) to that of corresponding oxide-containing Sc(2)(μ(2)-O)@C(s)(6)-C(82). © 2011 American Chemical Society

  19. Investigating the role of implicit prototypes in the prototype willingness model.

    PubMed

    Howell, Jennifer L; Ratliff, Kate A

    2017-06-01

    One useful theory to predict health behavior is the prototype-willingness model (PWM), which posits that people are more willing to engage in behavior to the extent that they have a positive view of the prototypical person who performs that behavior. The goal of the present research is to test whether adding an implicit measure of prototype favorability might improve explanatory power in the PWM. Two studies examined whether implicit prototype favorability uniquely predicted White women's intentions to engage in healthy sun behavior over the next 3-6 months, and their willingness to engage in risky sun behavior, should the opportunity arise. The results suggested that implicit prototype favorability, particularly implicit prototypes of those who engage in risky UV-related behaviors, uniquely predicted intentions to engage in healthy sun behavior and willingness to engage in risky sun behavior in the PWM.

  20. Development of a prototype infrared imaging bolometer for NSTX-U

    NASA Astrophysics Data System (ADS)

    van Eden, G. G.; Delgado-Aparicio, L. F.; Gray, T. K.; Jaworski, M. A.; Morgan, T. W.; Peterson, B. J.; Reinke, M. L.; Sano, R.; Mukai, K.; Differ/Pppl Collaboration; Nifs/Pppl Collaboration

    2015-11-01

    Measurements of the radiated power in fusion reactors are of high importance for studying detachment and the overall power balance. A prototype Infrared Video Bolometer (IRVB) is being developed for NSTX-U complementing resistive bolometer and AXUV diode diagnostics. The IRVB has proven to be a powerful tool on LHD and JT-60U for its 2D imaging quality and reactor environment compatibility. For NSTX-U, a poloidal view of the lower center stack and lower divertor are envisaged for the 2016 run campaign. The IRVB concept images radiation from the plasma onto a 2.5 μm thick 9 x 7 cm2 calibrated Pt foil and monitors its temperature evolution using an IR camera (SB focal plane, 2-12 μm, 128x128 pixels, 1.6 kHz). The power incident on the foil is calculated by solving the 2D +time heat diffusion equation. Benchtop characterization is presented, demonstrating a sensitivity of approximately 20 mK and a noise equivalent power density of 71.5 μW cm-2 for 4x20 bolometer super-pixels and a 50 Hz time response. The hardware design, optimization of camera and detector settings as well as first results of both synthetic and experimental origin are discussed.

  1. High confidence in falsely recognizing prototypical faces.

    PubMed

    Sampaio, Cristina; Reinke, Victoria; Mathews, Jeffrey; Swart, Alexandra; Wallinger, Stephen

    2018-06-01

    We applied a metacognitive approach to investigate confidence in recognition of prototypical faces. Participants were presented with sets of faces constructed digitally as deviations from prototype/base faces. Participants were then tested with a simple recognition task (Experiment 1) or a multiple-choice task (Experiment 2) for old and new items plus new prototypes, and they showed a high rate of confident false alarms to the prototypes. Confidence and accuracy relationship in this face recognition paradigm was found to be positive for standard items but negative for the prototypes; thus, it was contingent on the nature of the items used. The data have implications for lineups that employ match-to-suspect strategies.

  2. Analysis of supercritical CO{sub 2} cycle control strategies and dynamic response for Generation IV Reactors.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moisseytsev, A.; Sienicki, J. J.

    2011-04-12

    cycle efficiency of 49.3 %. The other approach involves reducing the minimum cycle pressure significantly below the critical pressure such that the temperature drop in the turbine is increased while the minimum cycle temperature is maintained above the critical temperature to prevent the formation of a liquid phase. The latter approach also involves the addition of a precooler and a third compressor before the main compressor to retain the benefits of compression near the critical point with the main compressor. For a minimum cycle pressure of 1 MPa, a cycle efficiency of 49.5% is achieved. Either approach opens up the door to applying the SCO{sub 2} cycle to the VHTR. In contrast, the SFR system typically has a core outlet-inlet temperature difference of about 150 C such that the standard recompression cycle is ideally suited for direct application to the SFR. The ANL Plant Dynamics Code has been modified for application to the VHTR and SFR when the reactor side dynamic behavior is calculated with another system level computer code such as SAS4A/SYSSYS-1 in the SFR case. The key modification involves modeling heat exchange in the RHX, accepting time dependent tabular input from the reactor code, and generating time dependent tabular input to the reactor code such that both the reactor and S-CO{sub 2} cycle sides can be calculated in a convergent iterative scheme. This approach retains the modeling benefits provided by the detailed reactor system level code and can be applied to any reactor system type incorporating a S-CO{sub 2} cycle. This approach was applied to the particular calculation of a scram scenario for a SFR in which the main and intermediate sodium pumps are not tripped and the generator is not disconnected from the electrical grid in order to enhance heat removal from the reactor system thereby enhancing the cooldown rate of the Na-to-CO{sub 2} RHX. The reactor side is calculated with SAS4A/SASSYS-1 while the S-CO{sub 2} cycle is calculated with the Plant

  3. Using EO-1 Hyperion Images to Prototype Environmental Products for Hyspiri

    NASA Technical Reports Server (NTRS)

    Middleton, Elizabeth M.; Campbell, Petya K. E.; Ungar, Stephen G.; Ong, Lawrence; Zhang, Qingyuan; Huemmrich, K. Fred; Mandl, Daniel J.; Frye, Stuart W.

    2011-01-01

    In November 2010, the Earth Observing One (EO-1) Satellite Mission will successfully complete a decade of Earth imaging by its two unique instruments, the Hyperion and the Advanced Land Imager (ALI). Both instruments are serving as prototypes for new orbital sensors, and the EO-1 is a heritage platform for the upcoming German mission, EnMAP. We provide an overview of the mission's lifetime. We briefly describe calibration & validation activities and overview the technical and scientific accomplishments of this mission. Some examples of the Mission Science Office (MSO) products are provided, as is an example of a image collected for disaster monitoring.

  4. Observations of CO2 in Comets C/2012 S1 ISON and C/2012 K1 PANSTARRS

    NASA Astrophysics Data System (ADS)

    McKay, Adam; Kelley, Michael; DiSanti, Michael; Cochran, Anita; Dello Russo, Neil; Lisse, Carey; Chanover, Nancy

    2013-10-01

    Comets have undergone very little thermal evolution in their lifetimes, resulting in a primitive composition. This primitive composition makes observations of comets very important tools for understanding the origin of the Solar System. The ices H2O, CO2, and CO are the primary ices present in cometary nuclei, and constraining their abundances has tremendous implications for the formation and evolutionary history of comets. Of these ices, H2O and CO can be observed from the ground, while CO2 cannot. A potentially effective tracer for CO2 in comets that is accessible from the ground is atomic oxygen. However, the relationship between these ices and atomic oxygen is only understood at a qualitative level. We propose to use Spitzer observations in IRAC's 4.5 micron band pass to observe the CO2 v3 band at 4.26 microns in comets C/2012 S1 ISON and C/2012 K1 PANSTARRS. These observations will be coordinated with observations of atomic oxygen obtained at Apache Point Observatory and McDonald Observatory and observations of H2O and CO at Keck and IRTF. These observations of H2O, CO2, and atomic oxygen in a cometary coma will increase our understanding of the link between these primary ices and atomic oxygen. With a complete understanding of the relationship between atomic oxygen and the primary ices on the nucleus, observations of atomic oxygen can serve as a powerful proxy for the production of CO2. In addition, ISON is the target of an extensive observing campaign led by NASA, and the proposed Spitzer observations fill a vital niche as the only observatory that can observe CO2 during both the near-perihelion time frame and significantly (months) after perihelion. Understanding the evolution of the CO2 abundance over the apparition is a key piece to understanding how the volatile compostion of the comet changes over the apparition.

  5. Laparoscopic prototype for optical sealing of renal blood vessels

    NASA Astrophysics Data System (ADS)

    Hardy, Luke A.; Hutchens, Thomas C.; Larson, Eric R.; Gonzalez, David A.; Chang, Chun-Hung; Nau, William H.; Fried, Nathaniel M.

    2017-02-01

    Energy-based, radiofrequency and ultrasonic devices provide rapid sealing of blood vessels during laparoscopic procedures. We are exploring infrared lasers as an alternative for vessel sealing with less collateral thermal damage. Previous studies demonstrated vessel sealing in an in vivo porcine model using a 1470-nm laser. However, the initial prototype was designed for open surgery and featured tissue clasping and light delivery mechanisms incompatible with laparoscopic surgery. In this study, a laparoscopic prototype similar to devices in surgical use was developed, and tests were conducted on porcine renal blood vessels. The 5-mm-OD prototype featured a traditional Maryland jaw configuration. Laser energy was delivered through a 550-μm-core fiber and side-delivery from the lower jaw, with beam dimensions of 18-mm-length x 1.2-mm-width. The 1470-nm diode laser delivered 68 W with 3 s activation time. A total of 69 porcine renal vessels with mean diameter of 3.3 +/- 1.7 mm were tested, ex vivo. Vessels smaller than 5 mm were consistently sealed (48/51) with burst pressures greater than malignant hypertension blood pressure (180 mmHg), averaging 1038 +/- 474 mmHg. Vessels larger than 5 mm were not consistently sealed (6/18), yielding burst pressures of only 174 +/- 221 mmHg. Seal width, thermal damage zone, and thermal spread averaged 1.7 +/- 0.8, 3.4 +/- 0.7, and 1.0 +/- 0.4 mm. A novel optical laparoscopic prototype with 5-mm- OD shaft integrated within a standard Maryland jaw design consistently sealed vessels less than 5 mm with minimal thermal spread. Further in vivo studies are planned to test performance across a variety of vessels and tissues.

  6. DANSS: Detector of the reactor AntiNeutrino based on Solid Scintillator

    NASA Astrophysics Data System (ADS)

    Alekseev, I.; Belov, V.; Brudanin, V.; Danilov, M.; Egorov, V.; Filosofov, D.; Fomina, M.; Hons, Z.; Kazartsev, S.; Kobyakin, A.; Kuznetsov, A.; Machikhiliyan, I.; Medvedev, D.; Nesterov, V.; Olshevsky, A.; Ponomarev, D.; Rozova, I.; Rumyantseva, N.; Rusinov, V.; Salamatin, A.; Shevchik, Ye.; Shirchenko, M.; Shitov, Yu.; Skrobova, N.; Starostin, A.; Svirida, D.; Tarkovsky, E.; Tikhomirov, I.; Vlášek, J.; Zhitnikov, I.; Zinatulina, D.

    2016-11-01

    The DANSS project is aimed at creating a relatively compact neutrino spectrometer which does not contain any flammable or other dangerous liquids and may therefore be located very close to the core of an industrial power reactor. As a result, it is expected that high neutrino flux would provide about 15,000 IBD interactions per day in the detector with a sensitive volume of 1 m3. High segmentation of the plastic scintillator will allow to suppress a background down to a ~1% level. Numerous tests performed with a simplified pilot prototype DANSSino under a 3 GWth reactor of the Kalinin NPP have demonstrated operability of the chosen design. The DANSS detector surrounded with a composite shield is movable by means of a special lifting gear, varying the distance to the reactor core in a range from 10 m to 12 m. Due to this feature, it could be used not only for the reactor monitoring, but also for fundamental research including short-range neutrino oscillations to the sterile state. Supposing one-year measurement, the sensitivity to the oscillation parameters is expected to reach a level of sin2(2θnew) ~ 5 × 10-3 with Δ m2 ⊂ (0.02-5.0) eV2.

  7. The HD(CP)2 Observational Prototype Experiment HOPE - Overview and Examples

    NASA Astrophysics Data System (ADS)

    Macke, Andreas

    2017-04-01

    The "HD(CP)2 Observational Prototype Experiment" (HOPE) was executed as a major 2-month field experiment in Jülich, Germany, performed in April and May 2013, followed by a smaller campaign in Melpitz, Germany in September 2013. HOPE has been designed to provide information on land-surface-atmospheric boundary layer exchange, aerosol, cloud and precipitation pattern for process studies and model evaluation with a focuses on the onset of clouds and precipitation in the convective atmospheric boundary layer. HOPE-Jülich instrumentation included a radio sounding station, 4 Doppler lidars, 4 Raman lidars,1 water vapour differential absorption lidar, 3 cloud radars, 5 microwave radiometers, 3 rain radars, 6 sky imagers, 99 pyranometers, and 4 Sun photometers operated in synergy at different supersites. The HOPE-Melpitz campaign combined ground-based remote sensing of aerosols and clouds with helicopter- and ballon-based in-situ observations in the atmospheric column and at the surface. HOPE provided an unprecedented collection of atmospheric dynamical, thermodynamical, and micro- and macrophysical properties of aerosols, clouds and precipitation with high spatial and temporal resolution within a cube of approximately 10 x 10 x 10 km3. HOPE data will significantly contribute to our understanding of boundary layer dynamics and the formation of clouds and precipitation. The datasets are made available through the Standardized Atmospheric Measurement Data SAMD archive at https://icdc.cen.uni-hamburg.de/index.php?id=samd. The presentation is based on an overview paper in ACP where results published in an ACP HOPE special issue are summarized, see http://www.atmos-chem-phys.net/special_issue366.html. Citation: Macke, A., Seifert, P., Baars, H., Beekmans, C., Behrendt, A., Bohn, B., Bühl, J., Crewell, S., Damian, T., Deneke, H., Düsing, S., Foth, A., Di Girolamo, P., Hammann, E., Heinze, R., Hirsikko, A., Kalisch, J., Kalthoff, N., Kinne, S., Kohler, M., Löhnert, U

  8. Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice[S

    PubMed Central

    Li, Shili; Choi, Hwa Y.; Fang, Fei; Fukasawa, Masashi; Uyeda, Kosaku; Hammer, Robert E.; Horton, Jay D.; Engelking, Luke J.; Liang, Guosheng

    2018-01-01

    Lipogenesis in liver is highest in the postprandial state; insulin activates SREBP-1c, which transcriptionally activates genes involved in FA synthesis, whereas glucose activates carbohydrate-responsive element-binding protein (ChREBP), which activates both glycolysis and FA synthesis. Whether SREBP-1c and ChREBP act independently of one another is unknown. Here, we characterized mice with liver-specific deletion of ChREBP (L-Chrebp−/− mice). Hepatic ChREBP deficiency resulted in reduced mRNA levels of glycolytic and lipogenic enzymes, particularly in response to sucrose refeeding following fasting, a dietary regimen that elicits maximal lipogenesis. mRNA and protein levels of SREBP-1c, a master transcriptional regulator of lipogenesis, were also reduced in L-Chrebp−/− livers. Adeno-associated virus-mediated restoration of nuclear SREBP-1c in L-Chrebp−/− mice normalized expression of a subset of lipogenic genes, while not affecting glycolytic genes. Conversely, ChREBP overexpression alone failed to support expression of lipogenic genes in the livers of mice lacking active SREBPs as a result of Scap deficiency. Together, these data show that SREBP-1c and ChREBP are both required for coordinated induction of glycolytic and lipogenic mRNAs. Whereas SREBP-1c mediates insulin’s induction of lipogenic genes, ChREBP mediates glucose’s induction of both glycolytic and lipogenic genes. These overlapping, but distinct, actions ensure that the liver synthesizes FAs only when insulin and carbohydrates are both present. PMID:29335275

  9. Conformational characterization of peptides rich in the cycloaliphatic C alpha,alpha-disubstituted glycine 1-aminocyclononane-1-carboxylic acid.

    PubMed

    Gatos, M; Formaggio, F; Crisma, M; Valle, G; Toniolo, C; Bonora, G M; Saviano, M; Iacovino, R; Menchise, V; Galdiero, S; Pedone, C; Benedetti, E

    1997-01-01

    A series of N- and C-protected, monodispersed homo-oligopeptides (to the pentamer level) from the cycloaliphatic C alpha,alpha-dialkylated glycine 1-aminocyclononane-1-carboxylic acid (Ac9c) and two Ala/Ac9c tripeptides have been synthesized by solution methods and fully characterized. The conformational preferences of all the model peptides were determined in deuterochloroform solution by FT-IR absorption and 1H-NMR. The molecular structures of the amino acid derivatives mCIAc-Ac9c-OH and Z-Ac9c-OtBu, the dipeptide pBrBz-(Ac9c)2-OtBu, the tetrapeptide Z-(Ac9c)4-OtBu, and the pentapeptide Z-(Ac9c)5-OtBu were determined in the crystal state by X-ray diffraction. Based on this information, the average geometry and the preferred conformation for the cyclononyl moiety of the Ac9c residue have been assessed. The backbone conformational data are strongly in favour of the conclusion that the Ac9c residue is a strong beta-turn and helix former. A comparison with the structural propensity of alpha-aminoisobutyric acid, the prototype of C alpha,alpha-dialkylated glycines, and the other extensively investigated members of the family of 1-aminocycloalkane-1-carboxylic acids (Acnc, with n = 3-8) is made and the implications for the use of the Ac9c residue in conformationally constrained analogues of bioactive peptides are briefly examined.

  10. Modelling of the anti-neutrino production and spectra from a Magnox reactor

    NASA Astrophysics Data System (ADS)

    Mills, Robert W.; Mountford, David J.; Coleman, Jonathon P.; Metelko, Carl; Murdoch, Matthew; Schnellbach, Yan-Jie

    2018-01-01

    The anti-neutrino source properties of a fission reactor are governed by the production and beta decay of the radionuclides present and the summation of their individual anti-neutrino spectra. The fission product radionuclide production changes during reactor operation and different fissioning species give rise to different product distributions. It is thus possible to determine some details of reactor operation, such as power, from the anti-neutrino emission to confirm safeguards records. Also according to some published calculations, it may be feasible to observe different anti-neutrino spectra depending on the fissile contents of the reactor fuel and thus determine the reactor's fissile material inventory during operation which could considerable improve safeguards. In mid-2014 the University of Liverpool deployed a prototype anti-neutrino detector at the Wylfa R1 station in Anglesey, United Kingdom based upon plastic scintillator technology developed for the T2K project. The deployment was used to develop the detector electronics and software until the reactor was finally shutdown in December 2015. To support the development of this detector technology for reactor monitoring and to understand its capabilities, the National Nuclear Laboratory modelled this graphite moderated and natural uranium fuelled reactor with existing codes used to support Magnox reactor operations and waste management. The 3D multi-physics code PANTHER was used to determine the individual powers of each fuel element (8×6152) during the year and a half period of monitoring based upon reactor records. The WIMS/TRAIL/FISPIN code route was then used to determine the radionuclide inventory of each nuclide on a daily basis in each element. These nuclide inventories were then used with the BTSPEC code to determine the anti-neutrino spectra and source strength using JEFF-3.1.1 data. Finally the anti-neutrino source from the reactor for each day during the year and a half of monitored reactor

  11. 13. 'Transverse Bracing for 1 208'101/2' C. to C. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. 'Transverse Bracing for 1 - 208'-10-1/2' C. to C. End Pins S. Tr. Thro. Skew Span, 6th Crossing of Sacramento River, So. Pac. Co., The Phoenix Bridge Co., C.O. 836D, Drawing No. 7, Scale - 1' = 1', Engineer - B.M. Krohn, May 11th `01, Slaughter' - Southern Pacific Railroad Shasta Route, Bridge No. 301.85, Milepost 301.85, Pollard Flat, Shasta County, CA

  12. SiC layer microstructure in AGR-1 and AGR-2 TRISO fuel particles and the influence of its variation on the effective diffusion of key fission products

    DOE PAGES

    Gerczak, Tyler J.; Hunn, John D.; Lowden, Richard A.; ...

    2016-08-15

    Tristructural isotropic (TRISO) coated particle fuel is a promising fuel form for advanced reactor concepts such as high temperature gas-cooled reactors (HTGR) and is being developed domestically under the US Department of Energy’s Nuclear Reactor Technologies Initiative in support of Advanced Reactor Technologies. The fuel development and qualification plan includes a series of fuel irradiations to demonstrate fuel performance from the laboratory to commercial scale. The first irradiation campaign, AGR-1, included four separate TRISO fuel variants composed of multiple, laboratory-scale coater batches. The second irradiation campaign, AGR-2, included TRISO fuel particles fabricated by BWX Technologies with a larger coater representativemore » of an industrial-scale system. The SiC layers of as-fabricated particles from the AGR-1 and AGR-2 irradiation campaigns have been investigated by electron backscatter diffraction (EBSD) to provide key information about the microstructural features relevant to fuel performance. The results of a comprehensive study of multiple particles from all constituent batches are reported. The observations indicate that there were microstructural differences between variants and among constituent batches in a single variant. Finally, insights on the influence of microstructure on the effective diffusivity of key fission products in the SiC layer are also discussed.« less

  13. Detector, collimator and real-time reconstructor for a new scanning-beam digital x-ray (SBDX) prototype.

    PubMed

    Speidel, Michael A; Tomkowiak, Michael T; Raval, Amish N; Dunkerley, David A P; Slagowski, Jordan M; Kahn, Paul; Ku, Jamie; Funk, Tobias

    Scanning-beam digital x-ray (SBDX) is an inverse geometry fluoroscopy system for low dose cardiac imaging. The use of a narrow scanned x-ray beam in SBDX reduces detected x-ray scatter and improves dose efficiency, however the tight beam collimation also limits the maximum achievable x-ray fluence. To increase the fluence available for imaging, we have constructed a new SBDX prototype with a wider x-ray beam, larger-area detector, and new real-time image reconstructor. Imaging is performed with a scanning source that generates 40,328 narrow overlapping projections from 71 × 71 focal spot positions for every 1/15 s scan period. A high speed 2-mm thick CdTe photon counting detector was constructed with 320×160 elements and 10.6 cm × 5.3 cm area (full readout every 1.28 μs), providing an 86% increase in area over the previous SBDX prototype. A matching multihole collimator was fabricated from layers of tungsten, brass, and lead, and a multi-GPU reconstructor was assembled to reconstruct the stream of captured detector images into full field-of-view images in real time. Thirty-two tomosynthetic planes spaced by 5 mm plus a multiplane composite image are produced for each scan frame. Noise equivalent quanta on the new SBDX prototype measured 63%-71% higher than the previous prototype. X-ray scatter fraction was 3.9-7.8% when imaging 23.3-32.6 cm acrylic phantoms, versus 2.3-4.2% with the previous prototype. Coronary angiographic imaging at 15 frame/s was successfully performed on the new SBDX prototype, with live display of either a multiplane composite or single plane image.

  14. High performance C/S composite cathodes with conventional carbonate-based electrolytes in Li-S battery.

    PubMed

    Zheng, Shiyou; Han, Pan; Han, Zhuo; Zhang, Huijuan; Tang, Zhihong; Yang, Junhe

    2014-04-29

    High stable C/S composites are fabricated by a novel high-temperature sulfur infusion into micro-mesoporous carbon method following with solvent cleaning treatment. The C/S composite cathodes show high Coulombic efficiency, long cycling stability and good rate capability in the electrolyte of 1.0 M LiPF6 + EC/DEC (1:1 v/v), for instance, the reversible capacity of the treated C/S-50 (50% S) cathode retains around 860 mAh/g even after 500 cycles and the Coulombic efficiency is close to 100%, which demonstrates the best electrochemical performance of carbon-sulfur composite cathodes using the carbonate-based electrolyte reported to date. It is believed that the chemical bond of C-S is responsible for the superior electrochemical properties in Li-S battery, that is, the strong interaction between S and carbon matrix significantly improves the conductivity of S, effectively buffers the structural strain/stress caused by the large volume change during lithiation/delithiation, completely eliminates the formation of high-order polysulfide intermediates, and substantially avoids the shuttle reaction and the side reaction between polysulfide anions and carbonate solvent, and thus enables the C/S cathode to use conventional carbonate-based electrolytes and achieve outstanding electrochemical properties in Li-S battery. The results may substantially contribute to the progress of the Li-S battery technology.

  15. 5 CFR 2640.301 - Waivers issued pursuant to 18 U.S.C. 208(b)(1).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...(b)(1). 2640.301 Section 2640.301 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS INTERPRETATION, EXEMPTIONS AND WAIVER GUIDANCE CONCERNING 18 U.S.C. 208 (ACTS AFFECTING A PERSONAL... profit or loss or cost of the matter to the company issuing the stock, the change in the value of real...

  16. [Circulating levels of MCP-1, VEGF-A, sICAM-1, sVCAM-1, sE-selectin and sVE-cadherin: Relationship with components of metabolic syndrome in young population].

    PubMed

    Guzmán-Guzmán, Iris Paola; Zaragoza-García, Oscar; Vences-Velázquez, Amalia; Castro-Alarcón, Natividad; Muñoz-Valle, José Francisco; Parra-Rojas, Isela

    2016-11-18

    Inflammation and endothelial dysfunction are considered the primary manifestations of the cardiovascular disease. Studies have established a relationship among components of metabolic syndrome (MetS) with inflammatory markers and the loss of permeability, vasoconstriction and vasodilatation endothelial. To determine the relationship among the concentrations of soluble endothelial dysfunction molecules and inflammation cytokines and components of the metabolic syndrome in young population. A study was performed in 240 young adult students ages 18-28 years. To define the presence of clinical and metabolic alterations and MetS the modified ATP-III criteria was considered. In all subjects were determined sociodemographic characteristics, anthropometric measures and the metabolic profile. Circulating levels of MCP-1, VEGF-A, sICAM-1, sVCAM-1, sE-selectin and sVE-cadherin were determined by ELISA immunoassay (Bioscience). Statistical analysis was performed using STATA statistical software v. 9.2. From all the participants, 44.6% had obesity, 59.9% had abdominal obesity, 49.6% low HDL-c and 16.7% high levels triglycerids. The 16.25% of the population showed 3 or more components of the MetS. Elevated MCP-1, sICAM-1 and sE-selectin levels were linked to the presence of obesity. In a model adjusted by age-gender, high soluble levels of MCP-1 and VEGF-A were linked with abdominal obesity (OR=1.83; 1.02-3.28 and OR=2.03; 1.15-3.56, respectively), as well as to the presence of the 2 components of MetS. sVCAM-1 levels were associated with impaired glucose (OR=4.74; 1.32-17.0); sE-selectin with low HDL-c (OR=1.99; 1.05-3.75), although sICAM-1 and sVE-cadherin were associated with impaired systolic blood pressure (OR=4.04; 1.24-13.1 and OR=6.28; 1.90-20.7, respectively). Levels of circulating MCP-1 and VEGF-A were associated with adiposity, levels of sVCAM-1 with the presence of impaired glucose, sE-selectin with low HDL-c, while the levels of sICAM-1 and sVE-cadherin were

  17. Wireless, in-vessel neutron monitor for initial core-loading of advanced breeder reactors

    NASA Technical Reports Server (NTRS)

    Delorenzo, J. T.; Kennedy, E. J.; Blalock, T. V.; Rochelle, J. M.; Chiles, M. M.; Valentine, K. H.

    1981-01-01

    An experimental wireless, in-vessel neutron monitor was developed to measure the reactivity of an advanced breeder reactor as the core is loaded for the first time to preclude an accidental critically incident. The environment is liquid sodium at a temperature of approx. 220 C, with negligible gamma or neutron radiation. With ultrasonic transmission of neutron data, no fundamental limitation was observed after tests at 230 C for 2000 h. The neutron sensitivity was approx. 1 count/s-nv, and the potential data transmission rate was approx. 10,000 counts/s.

  18. Tricyclic Pyrazoles. Part 5. Novel 1,4-Dihydroindeno[1,2-c]pyrazole CB2 Ligands Using Molecular Hybridization Based on Scaffold Hopping

    PubMed Central

    Murineddu, Gabriele; Asproni, Battistina; Ruiu, Stefania; Deligia, Francesco; Falzoi, Matteo; Pau, Amedeo; Thomas, Brian F; Zhang, Yanan; Pinna, Gérard A; Pani, Luca; Lazzari, Paolo

    2012-01-01

    In search of new selective CB2 ligands, the synthesis and preliminary biological evaluation of novel 1,4-dihydroindeno[1,2-c]pyrazole hybrids of the highly potent prototypicals 5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)-N-fenchyl-1H-pyrazole-3-carboxamide 1 and 1-(2,4-dichlorophenyl)-6-methyl-N-(piperidin-1-yl)-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide 2 are detailed. We postulated that the introduction of those pharmacophoric elements essential for activity of 1 in the tricyclic core of 2 might provide CB2 ligands with further improved receptor selectivity and biological activity. Among the compounds, 6-chloro-7-methyl-1-(2,4-dichlorophenyl)-N-fenchyl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide (22) exhibited low two digit nanomolar affinity for the cannabinoid CB2R and maintained a high level of CB2-selectivity. PMID:22876271

  19. Temporal integration of soil N2O fluxes: validation of IPNOA station automatic chamber prototype.

    PubMed

    Laville, P; Bosco, S; Volpi, I; Virgili, G; Neri, S; Continanza, D; Bonari, E

    2017-09-04

    The assessment of nitrous oxide (N 2 O) fluxes from agricultural soil surfaces still poses a major challenge to the scientific community. The evaluations of integrated soil fluxes of N 2 O are difficult owing to their lower emissions when compared with CO 2 . These emissions are also sporadic as environmental conditions act as a limiting factor. A station prototype was developed to integrate annual N 2 O and CO 2 emissions using an automatic chamber technique and infrared spectrometers within the LIFE project (IPNOA: LIFE11 ENV/IT/00032). It was installed from June 2014 to October 2015 in an experimental maize field in Tuscany. The detection limits for the fluxes were evaluated up to 1.6 ng N-N 2 O m 2  s -1 and 0.3 μg C-CO 2  m 2  s -1 . A cross-comparison carried out in September 2015 with the "mobile IPNOA prototype"; a high-sensibility transportable instrument already validated provided evidence of very similar values and highlighted flux assessment limitations according to the gas analyzers used. The permanent monitoring device showed that temporal distribution of N 2 O fluxes can be very large and discontinuous over short periods of less than 10 days and that N 2 O fluxes were below the detection limit of the instrumentation during approximately 70% of the measurement time. The N 2 O emission factors were estimated to 1.9% in 2014 and 1.7% in 2015, within the range of IPCC assessments.

  20. Constructing a dispersed fringe sensor prototype for the Giant Magellan Telescope

    NASA Astrophysics Data System (ADS)

    Frostig, Danielle; McLeod, Brian; AGWS Team

    2018-01-01

    The Giant Magellan Telescope (GMT) will be the world’s largest telescope upon completion. The GMT employs seven 8 m primary mirror segments and seven 1 m secondary mirror segments. One challenge of the GMT is keeping the seven pairs of mirror segments on the GMT in phase. In this project, we developed and began assembly on a design for a dispersed fringe sensor prototype consisting of an optical and basic mechanical layout. The prototype design will be tested on the Magellan Clay Telescope as an experiment for future phasing methods to be used on the GMT.

  1. Surface heat flux feedback controlled impurity seeding experiments with Alcator C-Mod’s high-Z vertical target plate divertor: performance, limitations and implications for fusion power reactors

    NASA Astrophysics Data System (ADS)

    Brunner, D.; Wolfe, S. M.; LaBombard, B.; Kuang, A. Q.; Lipschultz, B.; Reinke, M. L.; Hubbard, A.; Hughes, J.; Mumgaard, R. T.; Terry, J. L.; Umansky, M. V.; The Alcator C-Mod Team

    2017-08-01

    The Alcator C-Mod team has recently developed a feedback system to measure and control surface heat flux in real-time. The system uses real-time measurements of surface heat flux from surface thermocouples and a pulse-width modulated piezo valve to inject low-Z impurities (typically N2) into the private flux region. It has been used in C-Mod to mitigate peak surface heat fluxes  >40 MW m-2 down to  <10 MW m-2 while maintaining excellent core confinement, H 98  >  1. While the system works quite well under relatively steady conditions, use of it during transients has revealed important limitations on feedback control of impurity seeding in conventional vertical target plate divertors. In some cases, the system is unable to avoid plasma reattachment to the divertor plate or the formation of a confinement-damaging x-point MARFE. This is due to the small operational window for mitigated heat flux in the parameters of incident plasma heat flux, plasma density, and impurity density as well as the relatively slow response of the impurity gas injection system compared to plasma transients. Given the severe consequences for failure of such a system to operate reliably in a reactor, there is substantial risk that the conventional vertical target plate divertor will not provide an adequately controllable system in reactor-class devices. These considerations motivate the need to develop passively stable, highly compliant divertor configurations and experimental facilities that can test such possible solutions.

  2. A Prototype Silicon Compiler in Prolog

    DTIC Science & Technology

    1988-12-01

    A Prototype Silicon Compiler in Prolog 04 William Bush Gino Cheng Partrick C. McGeer Alvin M. Despain DTIC ELECTV JUL 281989 B Report No. UCB/CSD 88...the same register to variables in the same positions in invo- cation and head. Thus in ... g(A, B ),.. and g(X, Y) A and X share one register, and B ...example for a one-bit adder is given below. x = compl(or(and(c,or(a, b )),and(a, b ))). y = compl(or(and(x,or(a, b ,c)),and(a2b,c))). sum = compl(y). carry

  3. Measurement of the 1s2s ^1S0 - 1s2p ^3P1 interval in helium-like silicon.

    NASA Astrophysics Data System (ADS)

    Redshaw, M.; Harry, R.; Myers, E. G.; Weatherford, C. A.

    2001-05-01

    Accurate calculation of the energy levels of helium-like ions is a basic problem in relativistic atomic theory. For the n=3D2 levels at moderate Z, published calculations give all ``structure'' but not all explicit QED contributions to order (Zα)^4 a.u.(D.R. Plante, W.R. Johnson and J. Sapirstein, Phys. Rev. A 49), 3519 (1994).^, (K.T. Cheng, M.H. Chen, W.R. Johnson and J. Sapirstein, Phys. Rev. A 50), 247 (1994).. Measurements of the 1s2p ^3P - 1s2s ^3S transitions, which lie in the vacuum ultra-violet, are barely precise enough to challenge the theory. However, the intercombination 1s2s ^1S0 - 1s2p ^3P1 interval lies in the infra-red for Z<40 and enables precision measurements using laser spectroscopy(E.G. Myers, J.K. Thompson, E.P. Gavathas, N.R. Claussen, J.D. Silver and D.J.H. Howie, Phys. Rev. Lett. 75), 3637 (1995).. We aim to measure this interval in Si^12+ using a foil-stripped 1 MeV/u ion beam from the Florida State Van de Graaff accelerator and a single-mode c.w. Nd:YAG laser at 1.319 μm. To obtain a sufficient transition probability, the Si^12+ beam is merged co-linearly with the laser light inside an ultra-high finesse build-up cavity. The results should provide a clear test of current and developing calculations of QED contributions in two-electron ions.

  4. 11. 'Erection Plan, 1 208'101/2' C. to C. End ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. 'Erection Plan, 1 - 208'-10-1/2' C. to C. End Pins S. Tr. Thro. Skew Span, 6th Crossing Sacramento River, Pacific System, Southern Pacific Company, The Phoenix Bridge Co., C.O. 836D, Drawing No. 13, Scale 1/8' = 1'0', Engineer, B.M. Krohn, Draftsman, W.L. Clegg, Date, May 25th 1901' - Southern Pacific Railroad Shasta Route, Bridge No. 301.85, Milepost 301.85, Pollard Flat, Shasta County, CA

  5. Biodegradation of Jet Fuel-4 (JP-4) in Sequencing Batch Reactors

    DTIC Science & Technology

    1992-06-01

    nalw~eo %CUMENTATION PAGE__ _ _ _ _ _ _ _ _O 74S Ab -A258 020 L AW POi~W6 DATI .~ TYP AIMqm ,-& 0 U. glbs A~ I ma"&LFUN Mu BIODEGRADATION OF JET FUEL...Specific Objectives of This Proposal Are: 1. To assess the ability of C. resinae , P. chrysosporium and selected bacterial consortia to degrade individual...chemical components of JP-4. 2. To develop a sequencing batch reactor that utilizes C. resinae to degrade chemical components of JP-4 in contaminated

  6. Muon data from a water Cherenkov detector prototype at Colorado State University

    NASA Astrophysics Data System (ADS)

    Longo, Megan; Mostafa, Miguel

    2013-04-01

    The High Altitude Water Cherenkov (HAWC) Observatory is a very high energy gamma-ray experiment currently under construction in Sierra Negra in the state of Puebla, Mexico, at an altitude of 4,100 m a.s.l. The HAWC Observatory will consist of 300 water Cherenkov detectors (WCDs), each instrumented with three 8'' photomultiplier tubes (PMTs) and one 10'' high efficiency (HE) PMT. The PMTs are upward facing, anchored to the bottom of a 5 m deep by 7.3 m diameter steel tank, containing a multilayer hermetic plastic bag holding 200,000 L of purified water. The only full size WCD prototype outside of the HAWC site is located at Colorado State University (CSU) in Fort Collins, CO at an altitude of 1,525 m a.s.l. This prototype is instrumented with six 8'' PMTs, one 10'' HE PMT, and the same laser calibration system, electronics, and data acquisition system as the WCDs at the HAWC site. The CSU prototype is additionally equipped with scintillator paddles both under and above the volume of water, temperature probes (in the water, outside, and in the DAQ room), and one covered PMT. Preliminary results for muon rates and their temperature dependance using data collected with the CSU prototype will be presented.

  7. Improving Clinical Workflow in Ambulatory Care: Implemented Recommendations in an Innovation Prototype for the Veteran’s Health Administration

    PubMed Central

    Patterson, Emily S.; Lowry, Svetlana Z.; Ramaiah, Mala; Gibbons, Michael C.; Brick, David; Calco, Robert; Matton, Greg; Miller, Anne; Makar, Ellen; Ferrer, Jorge A.

    2015-01-01

    Introduction: Human factors workflow analyses in healthcare settings prior to technology implemented are recommended to improve workflow in ambulatory care settings. In this paper we describe how insights from a workflow analysis conducted by NIST were implemented in a software prototype developed for a Veteran’s Health Administration (VHA) VAi2 innovation project and associated lessons learned. Methods: We organize the original recommendations and associated stages and steps visualized in process maps from NIST and the VA’s lessons learned from implementing the recommendations in the VAi2 prototype according to four stages: 1) before the patient visit, 2) during the visit, 3) discharge, and 4) visit documentation. NIST recommendations to improve workflow in ambulatory care (outpatient) settings and process map representations were based on reflective statements collected during one-hour discussions with three physicians. The development of the VAi2 prototype was conducted initially independently from the NIST recommendations, but at a midpoint in the process development, all of the implementation elements were compared with the NIST recommendations and lessons learned were documented. Findings: Story-based displays and templates with default preliminary order sets were used to support scheduling, time-critical notifications, drafting medication orders, and supporting a diagnosis-based workflow. These templates enabled customization to the level of diagnostic uncertainty. Functionality was designed to support cooperative work across interdisciplinary team members, including shared documentation sessions with tracking of text modifications, medication lists, and patient education features. Displays were customized to the role and included access for consultants and site-defined educator teams. Discussion: Workflow, usability, and patient safety can be enhanced through clinician-centered design of electronic health records. The lessons learned from implementing

  8. Design and testing of the reactor-internal hydraulic control rod drive for the nuclear heating plant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Batheja, P.; Meier, W.J.; Rau, P.J.

    A hydraulically driven control rod is being developed at Kraftwerk Union for integration in the primary system of a small nuclear district heating reactor. An elaborate test program, under way for --3 yr, was initiated with a plexiglass rig to understand the basic principles. A design specification list was prepared, taking reactor boundary conditions and relevant German rules and regulations into account. Subsequently, an atmospheric loop for testing of components at 20 to 90/sup 0/C was erected. The objectives involved optimization of individual components such as a piston/cylinder drive unit, electromagnetic valves, and an ultrasonic position indication system as wellmore » as verification of computer codes. Based on the results obtained, full-scale components were designed and fabricated for a prototype test rig, which is currently in operation. Thus far, all atmospheric tests in this rig have been completed. Investigations under reactor temperature and pressure, followed by endurance tests, are under way. All tests to date have shown a reliable functioning of the hydraulic drive, including a novel ultrasonic position indication system.« less

  9. The Ongoing Impact of the U.S. Fast Reactor Integral Experiments Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    John D. Bess; Michael A. Pope; Harold F. McFarlane

    2012-11-01

    The creation of a large database of integral fast reactor physics experiments advanced nuclear science and technology in ways that were unachievable by less capital intensive and operationally challenging approaches. They enabled the compilation of integral physics benchmark data, validated (or not) analytical methods, and provided assurance of future rector designs The integral experiments performed at Argonne National Laboratory (ANL) represent decades of research performed to support fast reactor design and our understanding of neutronics behavior and reactor physics measurements. Experiments began in 1955 with the Zero Power Reactor No. 3 (ZPR-3) and terminated with the Zero Power Physics Reactormore » (ZPPR, originally the Zero Power Plutonium Reactor) in 1990 at the former ANL-West site in Idaho, which is now part of the Idaho National Laboratory (INL). Two additional critical assemblies, ZPR-6 and ZPR-9, operated at the ANL-East site in Illinois. A total of 128 fast reactor assemblies were constructed with these facilities [1]. The infrastructure and measurement capabilities are too expensive to be replicated in the modern era, making the integral database invaluable as the world pushes ahead with development of liquid metal cooled reactors.« less

  10. The Simulator Development for RDE Reactor

    NASA Astrophysics Data System (ADS)

    Subekti, Muhammad; Bakhri, Syaiful; Sunaryo, Geni Rina

    2018-02-01

    BATAN is proposing the construction of experimental power reactor (RDE reactor) for increasing the public acceptance on NPP development plan, proofing the safety level of the most advanced reactor by performing safety demonstration on the accidents such as Chernobyl and Fukushima, and owning the generation fourth (G4) reactor technology. For owning the reactor technology, the one of research activities is RDE’s simulator development that employing standard equation. The development utilizes standard point kinetic and thermal equation. The examination of the simulator carried out comparison in which the simulation’s calculation result has good agreement with assumed parameters and ChemCAD calculation results. The transient simulation describes the characteristic of the simulator to respond the variation of power increase of 1.5%/min, 2.5%/min, and 3.5%/min.

  11. Development of a prototype regenerable carbon dioxide absorber for portable life support systems. [for astronaut EVA

    NASA Technical Reports Server (NTRS)

    Onischak, M.; Baker, B.

    1977-01-01

    The design and development of a prototype carbon dioxide absorber using potassium carbonate (K2CO3) is described. Absorbers are constructed of thin, porous sheets of supported K2CO3 that are spirally wound to form a cylindrical reactor. Axial gas passages are formed between the porous sheets by corrugated screen material. Carbon dioxide and water in an enclosed life support system atmosphere react with potassium carbonate to form potassium bicarbonate. The potassium carbonate is regenerated by heating the potassium bicarbonate to 150 C at ambient pressure. The extravehicular mission design conditions are for one man for 8 h. Results are shown for a subunit test module investigating the effects of heat release, length-to-diameter ratio, and active cooling upon performance. The most important effect upon carbon dioxide removal is the temperature of the potassium carbonate.

  12. Sentinel-2 Level 2A Prototype Processor: Architecture, Algorithms And First Results

    NASA Astrophysics Data System (ADS)

    Muller-Wilm, Uwe; Louis, Jerome; Richter, Rudolf; Gascon, Ferran; Niezette, Marc

    2013-12-01

    Sen2Core is a prototype processor for Sentinel-2 Level 2A product processing and formatting. The processor is developed for and with ESA and performs the tasks of Atmospheric Correction and Scene Classification of Level 1C input data. Level 2A outputs are: Bottom-Of- Atmosphere (BOA) corrected reflectance images, Aerosol Optical Thickness-, Water Vapour-, Scene Classification maps and Quality indicators, including cloud and snow probabilities. The Level 2A Product Formatting performed by the processor follows the specification of the Level 1C User Product.

  13. Development of Thermoacoustic Sensors for Sodium-cooled Fast Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Heibel, Michael D.; Carvajal, Jorge V.; Ferroni, Paolo

    -scale facility was intended to be used to investigate the effect of sodium on the sensor and its performance (Subtask 4b). The Mechanism Engineering Test Loop (METL) large-scale facility was instead intended to be used to assess the additional effect of prototypical SFR structures, such as fuel assembly mockup or parts of the core restrain structure, on sensor performance (Subtask 4c). As discussed in Section 3.2.2.7, unexpected issues during the TAPS manufacturing process resulted in some activities being delayed, with the TAPS and USV facility developed to the point to be ready for testing in sodium, however without the possibility to actually perform such testing (including the testing in METL) due to the end of the program’s performance period. Overall, through the development and testing (in water only) of two TAPS devices (a First-Generation TAPS followed by an optimized Second-Generation TAPS), the project confirmed the capability of this technology to generate acoustic signals proportional to temperature, which can be detected through a network of accelerometers identified as the best-suited type of receivers for acoustic signal detection. Moreover, the project also developed a computational model to predict the characteristics of the acoustic signals being generated, which combines thermal analysis of the TAPS with Finite Element Modeling (FEM)-aided acoustic characterization of the system. This model was benchmarked against experimental data collected during the project and, although general agreement was obtained, some limitations of the modeling methods were identified, which require additional development. Additional testing is needed in order to assess the effect, on TAPS operation and performance, of environmental changes resulting from the transition from water to liquid sodium. Such testing, which is suggested to be performed in the future, should look specifically at 1) both the effect resulting from the different thermoacoustic behavior of sodium (relative

  14. Serrated Flow Behavior of Aisi 316l Austenitic Stainless Steel for Nuclear Reactors

    NASA Astrophysics Data System (ADS)

    Li, Qingshan; Shen, Yinzhong; Han, Pengcheng

    2017-10-01

    AISI 316L austenitic stainless steel is a candidate material for Generation IV reactors. In order to investigate the influence of temperature on serrated flow behavior, tensile tests were performed at temperatures ranging from 300 to 700 °C at an initial strain rate of 2×10-4 s-1. Another group of tensile tests were carried out at strain rates ranging from 1×10-4 to 1×10-2 s-1 at 600 °C to examine the influence of strain rates on serrated flow behavior. The steel exhibited serrated flow, suggesting the occurrence of dynamic strain ageing at 450-650°C. No plateau of yield stresses of the steel was observed at an initial strain rate of 2×10-4 s-1. The effective activation energy for serrated flow occurrence was calculated to be about 254.72 kJ/mol-1. Cr, Mn, Ni and Mo solute atoms are expected to be responsible for dynamic strain ageing at high temperatures of 450-650 °C in the steel.

  15. Influencing Gameplay in Support of Early Synthetic Prototyping Studies

    DTIC Science & Technology

    2016-06-01

    Synthetic Prototyping, acquisition, video games, crowdsourcing, Engineering Resilient Systems, science and technology, game environment 15. NUMBER OF...even though he did not play video games for entertainment, he would find time to participate in ESP (Vogt, Megiveron, & Smith, 2015). Meckler’s...reward used in video games: 1) score systems, 2) experience points, 3) item granting, 4) collectible resources, 5) achievement systems, 6) feedback

  16. C&S Enterprise, L.L.C.

    EPA Pesticide Factsheets

    The EPA is providing notice of a proposed Administrative Penalty Assessment against C & S Enterprise, L.L.C. (“Respondent”), a business located at 2454 480th Ave, Deep River, IA 52222, for alleged violations of the Clean Water Act at property owned by Resp

  17. Tyr115, gln165 and trp209 contribute to the 1, 2-epoxy-3-(p-nitrophenoxy)propane-conjugating activity of glutathione S-transferase cGSTM1-1.

    PubMed

    Chern, M K; Wu, T C; Hsieh, C H; Chou, C C; Liu, L F; Kuan, I C; Yeh, Y H; Hsiao, C D; Tam, M F

    2000-07-28

    We investigated the epoxidase activity of a class mu glutathione S-transferase (cGSTM1-1), using 1,2-epoxy-3-(p-nitrophenoxy)propane (EPNP) as substrate. Trp209 on the C-terminal tail, Arg107 on the alpha4 helix, Asp161 and Gln165 on the alpha6 helix of cGSTM1-1 were selected for mutagenesis and kinetic studies. A hydrophobic side-chain at residue 209 is needed for the epoxidase activity of cGSTM1-1. Replacing Trp209 with histidine, isoleucine or proline resulted in a fivefold to 28-fold decrease in the k(cat)(app) of the enzyme, while a modest 25 % decrease in the k(cat)(app) was observed for the W209F mutant. The rGSTM1-1 enzyme has serine at the correponding position. The k(cat)(app) of the S209W mutant is 2. 5-fold higher than that of the wild-type rGSTM1-1. A charged residue is needed at position 107 of cGSTM1-1. The K(m)(app)(GSH) of the R107L mutant is 38-fold lower than that of the wild-type enzyme. On the contrary, the R107E mutant has a K(m)(app)(GSH) and a k(cat)(app) that are 11-fold and 35 % lower than those of the wild-type cGSTM1-1. The substitutions of Gln165 with Glu or Leu have minimal effect on the affinity of the mutants towards GSH or EPNP. However, a discernible reduction in k(cat)(app) was observed. Asp161 is involved in maintaining the structural integrity of the enzyme. The K(m)(app)(GSH) of the D161L mutant is 616-fold higher than that of the wild-type enzyme. In the hydrogen/deuterium exchange experiments, this mutant has the highest level of deuteration among all the proteins tested. We also elucidated the structure of cGSTM1-1 co-crystallized with the glutathionyl-conjugated 1, 2-epoxy-3-(p-nitrophenoxy)propane (EPNP) at 2.8 A resolution. The product found in the active site was 1-hydroxy-2-(S-glutathionyl)-3-(p-nitrophenoxy)propane, instead of the conventional 2-hydroxy isomer. The EPNP moiety orients towards Arg107 and Gln165 in dimer AB, and protrudes into a hydrophobic region formed by the loop connecting beta1 and alpha1 and part

  18. Phase Equilibria of a S- and C-Poor Lunar Core

    NASA Technical Reports Server (NTRS)

    Righter, K.; Pando, K.; Go, B. M.; Danielson, L. R.; Habermann, M.

    2016-01-01

    The composition of the lunar core can have a large impact on its thermal evolution, possible early dynamo creation, and physical state. Geochemical measurements have placed better constraints on the S and C content of the lunar mantle. In this study we have carried out phase equilibrium studies of geochemically plausible S- and C-poor lunar core compositions in the Fe-Ni-S-C system, and apply them to the early history of the Moon. We chose two bulk core compositions, with differing S and C content based on geochemical analyses of S and C trapped melts in Apollo samples, and on the partitioning of S and C between metal and silicate. This approach allowed calculation of core S and C contents - 90% Fe, 9% Ni, 0.5% C, and 0.375% S by weight; a second composition contained 1% each of S and C. Experiments were carried out from 1473K to 1973K and 1 GPa to 5 GPa, in piston cylinder and multi- anvil apparatuses. Combination of the thermal model of with our results, shows that a solid inner core (and therefore initiation of a dynamo) may have been possible in the earliest history of the Moon (approximately 4.2 Ga ago), in agreement with. Thus a volatile poor lunar core may explain the thermal and magnetic history of the Moon.

  19. Design and development of a prototype wet oxidation system for the reclamation of water and the disposition of waste residues onboard space vehicles

    NASA Technical Reports Server (NTRS)

    Jagow, R. B.

    1972-01-01

    Laboratory investigations to define optimum process conditions for oxidation of fecal/urine slurries were conducted in a one-liter batch reactor. The results of these tests formed the basis for the design, fabrication, and testing of an initial prototype system, including a 100-hour design verification test. Areas of further development were identified during this test. Development of a high pressure slurry pump, materials corrosion studies, oxygen supply trade studies, comparison of salt removal water recovery devices, ammonia removal investigation, development of a solids grinder, reactor design studies and bearing life tests, and development of shutoff valves and a back pressure regulator were undertaken. The development work has progressed to the point where a prototype system suitable for manned chamber testing can be fabricated and tested with a high degree of confidence of success.

  20. Use of Nitrogen Trifluoride To Purify Molten Salt Reactor Coolant and Heat Transfer Fluoride Salts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scheele, Randall D.; Casella, Andrew M.; McNamara, Bruce K.

    2017-05-02

    Abstract: The molten salt cooled nuclear reactor is included as one of the Generation IV reactor types. One of the challenges with the implementation of this reactor is purifying and maintaining the purity of the various molten fluoride salts that will be used as coolants. The method used for Oak Ridge National Laboratory’s molten salt experimental test reactor was to treat the coolant with a mixture of H2 and HF at 600°C. In this article we evaluate thermal NF3 treatment for purifying molten fluoride salt coolant candidates based on NF3’s 1) past use to purify fluoride salts, 2) other industrialmore » uses, 3) commercial availability, 4) operational, chemical, and health hazards, 5) environmental effects and environmental risk management methods, 6) corrosive properties, and 7) thermodynamic potential to eliminate impurities that could arise due to exposure to water and oxygen. Our evaluation indicates that nitrogen trifluoride is a viable and safer alternative to the previous method.« less

  1. 52. ARAII. Support piers for SL1 reactor building. September 5, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    52. ARA-II. Support piers for SL-1 reactor building. September 5, 1957. Ineel photo no. 57-4398. Photographer: Ken Mansfield. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  2. Fourier Transform Spectroscopy of Carbonyl Sulfide from 4800 to 8000 cm -1and New Global Analysis of 16O 12C 32S

    NASA Astrophysics Data System (ADS)

    Rbaihi, E.; Belafhal, A.; Vander Auwera, J.; Naı̈m, S.; Fayt, A.

    1998-09-01

    We have measured the FT spectrum of natural OCS from 4800 to 8000 cm-1with a near Doppler resolution and a line-position accuracy between 2 and 8 × 10-4cm-1. For the normal isotopic species16O12C32S, 37 vibrational transitions have been analyzed for both frequencies and intensities. We also report six bands of16O12C34S, five bands of16O13C32S, two bands of16O12C33S, and two bands of18O12C32S. Important effective Herman-Wallis terms are explained by the anharmonic resonances between closely spaced states. As those results complete the study of the Fourier transform spectra of natural carbonyl sulfide from 1800 to 8000 cm-1, a new global rovibrational analysis of16O12C32S has been performed. We have determined a set of 148 molecular parameters, and a statistical agreement is obtained with all the available experimental data.

  3. Development Status for a Combined Solid Oxide Co-Electrolyzer and Carbon Formation Reactor System for Oxygen Regeneration

    NASA Technical Reports Server (NTRS)

    Green, Robert D.; Matter, Paul H.; Holt, Chris; Beachy, Michael; Gaydos, James; Farmer, Serene C.; Setlock, John

    2016-01-01

    A critical component in spacecraft life support loop closure is the removal of carbon dioxide (CO2, produced by the crew) from the cabin atmosphere and chemical reduction of this CO2 to recover the oxygen. In 2015, we initiated development of an oxygen recovery system for life support applications consisting of a solid oxide co-electrolyzer (SOCE) and a carbon formation reactor (CFR). The SOCE electrolyzes a combined stream of carbon dioxide (CO2) and water (H2O) gas mixtures to produce synthesis gas (e.g., CO and H2 gas) and pure dry oxygen as separate products. This SOCE is being developed from a NASA GRC solid oxide fuel cell and stack design originally developed for aeronautics long-duration power applications. The CFR, being developed by pHMatter LLC, takes the CO and H2 output from the SOCE, and converts it primarily to solid carbon (C(s)) and H2O and CO2. Although the solid carbon accumulates in the CFR, the innovative design allows easy removal of the carbon product, requiring minimal crew member (CM) time and low resupply mass (1.0 kg/year/CM) for replacement of the solid carbon catalyst, a significant improvement over previous Bosch reactor approaches. In this work, we will provide a status of our Phase I efforts in the development and testing of both the SOCE and CFR prototype units, along with an initial assessment of the combined SOCE-CFR system, including a mass and power projections, along with an estimate of the oxygen recovery rate.

  4. Posttest data analysis and assessment of TRAC-BD1/MOD1 with data from a Full Integral Simulation Test (FIST) power transient experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wheatley, P.D.; Wagner, K.C.

    The FIST power transient test 6PMC2 was analyzed to further the understanding of the FIST facility and provide an assessment of TRAC-BD1/MOD1. FIST power transient 6PMC2 investigated the thermal-hydraulic response following inadvertent closure of the main steam isolation valve and the subsequent failure of the reactor to scram. Failure of the high pressure core spray system was also assumed, resulting on only the reactor core isolation cooling flow for inventory makeup during the transient. The experiment was a sensitivity study with relatively high core power and low makeup rates. This study provides one of the first opportunities to assess TRAC-BD1/MOD1more » under power transient and natural circulation conditions with data from a facility with prototypical BWR geometry. The power transient test was analyzed with emphasis on the following phenomena; (a) the system pressure response, (b) the natural circulation flows and rates, and (c) the heater rod cladding temperature response. Based on the results of this study, TRAC-BD1/MOD1 can be expected to calculate the thermal-hydraulic behavior of a BWR during a power transient.« less

  5. The PreS2 activator MHBst of hepatitis B virus activates c-raf-1/Erk2 signaling in transgenic mice

    PubMed Central

    Hildt, Eberhard; Munz, Barbara; Saher, Gesine; Reifenberg, Kurt; Hofschneider, Peter Hans

    2002-01-01

    The large hepatitis B virus (HBV) surface protein (LHBs) and C-terminally truncated middle size surface proteins (MHBst) form the family of the PreS2 activator proteins of HBV. Their transcriptional activator function is based on the cytoplasmic orientation of the PreS2 domain. MHBst activators are paradigmatic for this class of activators. Here we report that MHBst is protein kinase C (PKC)-dependently phosphorylated at Ser28. The integrity of the phosphorylation site is essential for the activator function. MHBst triggers PKC-dependent activation of c-Raf-1/Erk2 signaling that is a prerequisite for MHBst-dependent activation of AP-1 and NF-κB. To analyze the pathophysiological relevance of these data in vivo, transgenic mice were established that produce the PreS2 activator MHBst specifically in the liver. In these mice, a permanent PreS2-dependent specific activation of c-Raf-1/Erk2 signaling was observed, resulting in an increased hepatocyte proliferation rate. In transgenics older than 15 months, an increased incidence of liver tumors occurs. These data suggest that PreS2 activators LHBs and MHBst exert a tumor promoter-like function by activation of key enzymes of proliferation control. PMID:11847101

  6. Design of a prototype flow microreactor for synthetic biology in vitro.

    PubMed

    Boehm, Christian R; Freemont, Paul S; Ces, Oscar

    2013-09-07

    As a reference platform for in vitro synthetic biology, we have developed a prototype flow microreactor for enzymatic biosynthesis. We report the design, implementation, and computer-aided optimisation of a three-step model pathway within a microfluidic reactor. A packed bed format was shown to be optimal for enzyme compartmentalisation after experimental evaluation of several approaches. The specific substrate conversion efficiency could significantly be improved by an optimised parameter set obtained by computational modelling. Our microreactor design provides a platform to explore new in vitro synthetic biology solutions for industrial biosynthesis.

  7. 78 FR 32279 - Advisory Committee On Reactor Safeguards; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards; Notice of Meeting In accordance with the purposes of Sections 29 and 182b of the Atomic Energy Act (42 U.S.C. 2039, 2232b), the Advisory Committee on Reactor Safeguards (ACRS) will hold a meeting on June 5-7, 2013, 11545 Rockville Pike...

  8. Application of Cognitive Task Analysis in User Requirements and Prototype Design Presentation/Briefing

    DTIC Science & Technology

    2005-10-01

    AFRL-HE-WP-TP-2005-0030 AIR FORCE RESEARCH LABORATORY Application of Cognitive Task Analysis in User Requirements and Prototype Design Presentation...TITLE AND SUBTITLE 5a. CONTRACT NUMBER FA8650-04-C-6406 Application of Cognitive Task Analysis in User Requirements 5b.GRANTNUMBER and Prototype...maintainer experience 21 21 Questions & Answers Application of Cognitive Task Analysis in User Requirements Definition and Prototype Design Christopher Curtis

  9. Precise measurement of spin-averaged {chi}{sub cJ}(1P) mass using photon conversions in {psi}(2S){yields}{gamma}{chi}{sub cJ}

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ablikim, M.; Bai, J.Z.; Bian, J.G.

    2005-05-01

    Using photon conversions to e{sup +}e{sup -} pairs, the energy spectrum of inclusive photons from {psi}(2S) radiative decays is measured with photon energy resolution ({sigma}{sub E{sub {gamma}}}) in the range from 2.3 to 3.8 MeV by BESII at the Beijing Electron-Positron Collider. The {chi}{sub cJ}(1P) states (J=0,1,2) are clearly observed, and their masses and the spin-averaged {chi}{sub cJ} mass are determined to be M{sub {chi}{sub c}{sub 0}}=3414.21{+-}0.39{+-}0.27, M{sub {chi}{sub c}{sub 1}}=3510.30{+-}0.14{+-}0.16, M{sub {chi}{sub c}{sub 2}}=3555.70{+-}0.59{+-}0.39, and M({sup 3}P{sub cog})=3524.85{+-}0.32{+-}0.30 MeV/c{sup 2}, respectively.

  10. 19 CFR 10.91 - Prototypes used exclusively for product development and testing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... prototypes or any part(s) of the prototypes may be sold as scrap, waste, or for recycling, as prescribed in..., or for recycling. This includes a prototype or any part thereof that is incorporated into another product, as scrap, waste, or recycled material. If sold as scrap, waste, or for recycling, applicable duty...

  11. 19 CFR 10.91 - Prototypes used exclusively for product development and testing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... prototypes or any part(s) of the prototypes may be sold as scrap, waste, or for recycling, as prescribed in..., or for recycling. This includes a prototype or any part thereof that is incorporated into another product, as scrap, waste, or recycled material. If sold as scrap, waste, or for recycling, applicable duty...

  12. 19 CFR 10.91 - Prototypes used exclusively for product development and testing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... prototypes or any part(s) of the prototypes may be sold as scrap, waste, or for recycling, as prescribed in..., or for recycling. This includes a prototype or any part thereof that is incorporated into another product, as scrap, waste, or recycled material. If sold as scrap, waste, or for recycling, applicable duty...

  13. 19 CFR 10.91 - Prototypes used exclusively for product development and testing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... prototypes or any part(s) of the prototypes may be sold as scrap, waste, or for recycling, as prescribed in..., or for recycling. This includes a prototype or any part thereof that is incorporated into another product, as scrap, waste, or recycled material. If sold as scrap, waste, or for recycling, applicable duty...

  14. 19 CFR 10.91 - Prototypes used exclusively for product development and testing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... prototypes or any part(s) of the prototypes may be sold as scrap, waste, or for recycling, as prescribed in..., or for recycling. This includes a prototype or any part thereof that is incorporated into another product, as scrap, waste, or recycled material. If sold as scrap, waste, or for recycling, applicable duty...

  15. An APC/C-Cdh1 Biosensor Reveals the Dynamics of Cdh1 Inactivation at the G1/S Transition.

    PubMed

    Ondracka, Andrej; Robbins, Jonathan A; Cross, Frederick R

    2016-01-01

    B-type cyclin-dependent kinase activity must be turned off for mitotic exit and G1 stabilization. B-type cyclin degradation is mediated by the anaphase-promoting complex/cyclosome (APC/C); during and after mitotic exit, APC/C is dependent on Cdh1. Cdh1 is in turn phosphorylated and inactivated by cyclin-CDK at the Start transition of the new cell cycle. We developed a biosensor to assess the cell cycle dynamics of APC/C-Cdh1. Nuclear exit of the G1 transcriptional repressor Whi5 is a known marker of Start; APC/C-Cdh1 is inactivated 12 min after Whi5 nuclear exit with little measurable cell-to-cell timing variability. Multiple phosphorylation sites on Cdh1 act in a redundant manner to repress its activity. Reducing the number of phosphorylation sites on Cdh1 can to some extent be tolerated for cell viability, but it increases variability in timing of APC/C-Cdh1 inactivation. Mutants with minimal subsets of phosphorylation sites required for viability exhibit striking stochasticity in multiple responses including budding, nuclear division, and APC/C-Cdh1 activity itself. Multiple cyclin-CDK complexes, as well as the stoichiometric inhibitor Acm1, contribute to APC/C-Cdh1 inactivation; this redundant control is likely to promote rapid and reliable APC/C-Cdh1 inactivation immediately following the Start transition.

  16. Preliminary design of a prototype particulate stack sampler. [For stack gas temperature under 300/sup 0/C

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Elder, J.C.; Littlefield, L.G.; Tillery, M.I.

    1978-06-01

    A preliminary design of a prototype particulate stack sampler (PPSS) has been prepared, and development of several components is under way. The objective of this Environmental Protection Agency (EPA)-sponsored program is to develop and demonstrate a prototype sampler with capabilities similar to EPA Method 5 apparatus but without some of the more troublesome aspects. Features of the new design include higher sampling flow; display (on demand) of all variables and periodic calculation of percent isokinetic, sample volume, and stack velocity; automatic control of probe and filter heaters; stainless steel surfaces in contact with the sample stream; single-point particle size separationmore » in the probe nozzle; null-probe capability in the nozzle; and lower weight in the components of the sampling train. Design considerations will limit use of the PPSS to stack gas temperatures under approximately 300/sup 0/C, which will exclude sampling some high-temperature stacks such as incinerators. Although need for filter weighing has not been eliminated in the new design, introduction of a variable-slit virtual impactor nozzle may eliminate the need for mass analysis of particles washed from the probe. Component development has shown some promise for continuous humidity measurement by an in-line wet-bulb, dry-bulb psychrometer.« less

  17. Flight Test of GL-1 Glider Half Scale Prototype

    NASA Astrophysics Data System (ADS)

    Fikri Zulkarnain, Muhammad; Fazlur Rahman, Muhammad; Luthfi Imam Nurhakim, Muhammad; Arifianto, Ony; Mulyanto, Taufiq

    2018-04-01

    GL-1 is a single-seat mid-performance glider, designed to be Indonesian National Glider. The Glider have been developing since 2014. The development produced a half scale prototype called BL-1, which had accomplished static test in 2016, then followed by first flight test at April 20th 2017, and second flight test at May 21st 2017. The purpose of the flight test was to obtain familiarization of the aircraft, aerodynamics characteristics and flow visualization, with data from flight recorded in FDR. The flight test resulted in two flights with total length of 21 minutes. The data from FDR and flight test documents extracted to analyze the characteristics and behavior of the aircraft during flight test. The aerodynamics characteristic was close to analytical results. The control was good; however, the effectiveness of control surface may need to be further analyzed. The result of the flight test will be used as a reference for further improvements and may need further testing.

  18. Prototyping the E-ELT M1 local control system communication infrastructure

    NASA Astrophysics Data System (ADS)

    Argomedo, J.; Kornweibel, N.; Grudzien, T.; Dimmler, M.; Andolfato, L.; Barriga, P.

    2016-08-01

    The primary mirror of the E-ELT is composed of 798 hexagonal segments of about 1.45 meters across. Each segment can be moved in piston and tip-tilt using three position actuators. Inductive edge sensors are used to provide feedback for global reconstruction of the mirror shape. The E-ELT M1 Local Control System will provide a deterministic infrastructure for collecting edge sensor and actuators readings and distribute the new position actuators references while at the same time providing failure detection, isolation and notification, synchronization, monitoring and configuration management. The present paper describes the prototyping activities carried out to verify the feasibility of the E-ELT M1 local control system communication architecture design and assess its performance and potential limitations.

  19. Inactivation of Bacteria S. aureus ATCC 25923 and S. Thyphimurium ATCC 14 028 Influence of UV-HPEF

    NASA Astrophysics Data System (ADS)

    Bakri, A.; Hariono, B.; Utami, M. M. D.; Sutrisno

    2018-01-01

    The research was objected to study the performance of the UV unit - HPEF in inactivating bacteria population of Gram-positive (S aureus ATCC 25923) and Gram-negative (S Thyphimurium ATCC 14028) inoculated in sterilized goat’s milk. UV pasteurization instrument employed three reactors constructed in series UV-C system at 10 W, 253.7 nm wavelength made in Kada (USA) Inc. with 1.8 J/cm2 dose per reactor. HPEF instrument used high pulsed electric field at 31.67 kV/cm, 15 Hz and goat’s milk rate at 4:32 ± 0.71 cc/second. Pathogenic bacteria was observed According to Indonesian National Standard 01-2782-1998. Inactivation rate of pathogenic bacteria ie S Thyphimurium ATCC 14028 and S. aureus ATCC 25923 was 0.28 and 0.19 log cycle or 6.35 and 4.34 log cfu/ml/hour, respectively; D value was 0.16 and 0.23 hour with k value was 14.62 and 10 hour-1 respectively.

  20. Far-ultraviolet observations of comet C/2012 S1 (ISON) with a sounding-rocket-borne instrument

    NASA Astrophysics Data System (ADS)

    Feldman, P.; McCandliss, S.; Weaver, H.; Fleming, B.; Redwine, K.; Li, M.; Kutyrev, A.; Moseley, S.

    2014-07-01

    We report on a far-ultraviolet observation of comet C/2012 S1 (ISON) made from a Black Brant IX sounding rocket that was launched on 20 November 2013 at 04:40 MST from the White Sands Missile Range, New Mexico, when the comet was 0.44 au from the Sun, 0.86 au from the Earth, and at a solar elongation of 26.3 degrees pre-perihelion. At the time of launch the comet was 0.1 degrees below ground horizon. The payload reached an apogee of 279 km and the total time pointed at the comet was 353 s. The sounding rocket borne instrument was our wide-field multi-object spectro-telescope called FORTIS (Far-UV Off Rowland-circle Telescope for Imaging and Spectroscopy), which is a Gregorian telescope (concave primary and secondary optics) with a triaxial figured diffractive secondary that provides an on-axis imaging channel and two off-axis spectral channels in a common focal plane. A multi-object spectroscopic capability is provided by an array of microshutters placed at the prime focus of the telescope. Our microshutter array (MSA) is based on prototype devices of the large area arrays developed at Goddard Space Flight Center (GSFC) for use in the Near Infrared Spectrograph (NIRSpec) on the James Webb Space Telescope (JWST). The imaging channel on FORTIS has a field-of-view (FOV) of 0.5 degrees square. The MSA allows selection of up to 43 individual regions, each with a solid angle of 12.4'' × 36.9'', for spectral acquisition over the 800--1950 Ångstroms bandpass at a resolution of 6 Ångstroms. However a problem with addressing the MSA prevented the acquisition of spectra through individual slits. Nonetheless spectrally confused images, dominated by Lyman-alpha emission from the comet, were acquired in both off-axis spectral channels. The imaging channel uses a CaF_2/MgF_2 cylindrical doublet to correct for astigmatism introduced by the triaxial secondary, which restricts the bandpass to wavelengths longward of 1280 Ångstroms. The corrected imaging resolution is

  1. Recent results obtained on the APEX 12 m antenna with the ArTeMiS prototype camera

    NASA Astrophysics Data System (ADS)

    Talvard, M.; André, P.; Rodriguez, L.; Le-Pennec, Y.; De Breuck, C.; Revéret, V.; Agnèse, P.; Boulade, O.; Doumayrou, E.; Dubreuil, D.; Ercolani, E.; Gallais, P.; Horeau, B.; Lagage, PO; Leriche, B.; Lortholary, M.; Martignac, J.; Minier, V.; Pantin, E.; Rabanus, D.; Relland, J.; Willmann, G.

    2008-07-01

    ArTeMiS is a camera designed to operate on large ground based submillimetric telescopes in the 3 atmospheric windows 200, 350 and 450 µm. The focal plane of this camera will be equipped with 5760 bolometric pixels cooled down at 300 mK with an autonomous cryogenic system. The pixels have been manufactured, based on the same technology processes as used for the Herschel-PACS space photometer. We review in this paper the present status and the future plans of this project. A prototype camera, named P-ArTeMiS, has been developed and successfully tested on the KOSMA telescope in 2006 at Gornergrat 3100m, Switzerland. Preliminary results were presented at the previous SPIE conference in Orlando (Talvard et al, 2006). Since then, the prototype camera has been proposed and successfully installed on APEX, a 12 m antenna operated by the Max Planck Institute für Radioastronomie, the European Southern Observatory and the Onsala Space Observatory on the Chajnantor site at 5100 m altitude in Chile. Two runs have been achieved in 2007, first in March and the latter in November. We present in the second part of this paper the first processed images obtained on star forming regions and on circumstellar and debris disks. Calculated sensitivities are compared with expectations. These illustrate the improvements achieved on P-ArTeMiS during the 3 experimental campaigns.

  2. Reactor antineutrino detector iDREAM.

    NASA Astrophysics Data System (ADS)

    Gromov, M. B.; Lukyanchenko, G. A.; Novikova, G. J.; Obinyakov, B. A.; Oralbaev, A. Y.; Skorokhvatov, M. D.; Sukhotin, S. V.; Chepurnov, A. S.; Etenko, A. V.

    2017-09-01

    Industrial Detector for Reactor Antineutrino Monitoring (iDREAM) is a compact (≈ 3.5m 2) industrial electron antineutrino spectrometer. It is dedicated for remote monitoring of PWR reactor operational modes by neutrino method in real-time. Measurements of antineutrino flux from PWR allow to estimate a fuel mixture in active zone and to check the status of the reactor campaign for non-proliferation purposes. LAB-based gadolinium doped scintillator is exploited as a target. Multizone architecture of the detector with gamma-catcher surrounding fiducial volume and plastic muon veto above and below ensure high efficiency of IBD detection and background suppression. DAQ is based on Flash ADC with PSD discrimination algorithms while digital trigger is programmable and flexible due to FPGA. The prototype detector was started up in 2014. Preliminary works on registration Cerenkov radiation produced by cosmic muons were established with distilled water inside the detector in order to test electronic and slow control systems. Also in parallel a long-term measurements with different scintillator samples were conducted.

  3. IMPROVEMENTS RELATING TO NUCLEAR REACTOR CORE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bell, F.R.

    1963-03-01

    A nuclear reactor core composed of a number of stacked horizontal layers is described. Each layer is made up of elements of moderator material of equal height and of generally hexagonal cross-section. Each element has holes containing nuclear fuel and separate ones for coolant. (C.E.S.)

  4. Utilization survey of prototype structural test article

    NASA Technical Reports Server (NTRS)

    Baber, S.; Mcdaniel, H. M.; Berry, M. J.

    1974-01-01

    A survey was conducted of six aerospace companies and two NASA agencies to determine how prototype structural test articles are used in flight operations. The prototype structures are airframes and similar devices which are used for testing and generally are not flown. The survey indicated the following: (1) prototype test articles are not being discarded after development testing is complete, but are used for other purposes, (2) only two cases of prototypes being refurbished and flown were identified, (3) protective devices and inspection techniques are available to prevent or minimize test article damage, (4) substitute programs from design verification are availabel in lieu of using prototype structural articles, and (5) there is a trend away from dedicated test articles. Four options based on these study results were identified to reduce test and hardware costs without compromising reliability of the flight program.

  5. Tritium resources available for fusion reactors

    NASA Astrophysics Data System (ADS)

    Kovari, M.; Coleman, M.; Cristescu, I.; Smith, R.

    2018-02-01

    The tritium required for ITER will be supplied from the CANDU production in Ontario, but while Ontario may be able to supply 8 kg for a DEMO fusion reactor in the mid-2050s, it will not be able to provide 10 kg at any realistic starting time. The tritium required to start DEMO will depend on advances in plasma fuelling efficiency, burnup fraction, and tritium processing technology. It is in theory possible to start up a fusion reactor with little or no tritium, but at an estimated cost of 2 billion per kilogram of tritium saved, it is not economically sensible. Some heavy water reactor tritium production scenarios with varying degrees of optimism are presented, with the assumption that only Canada, the Republic of Korea, and Romania make tritium available to the fusion community. Results for the tritium available for DEMO in 2055 range from zero to 30 kg. CANDU and similar heavy water reactors could in theory generate additional tritium in a number of ways: (a) adjuster rods containing lithium could be used, giving 0.13 kg per year per reactor; (b) a fuel bundle with a burnable absorber has been designed for CANDU reactors, which might be adapted for tritium production; (c) tritium production could be increased by 0.05 kg per year per reactor by doping the moderator with lithium-6. If a fusion reactor is started up around 2055, governments in Canada, Argentina, China, India, South Korea and Romania will have the opportunity in the years leading up to that to take appropriate steps: (a) build, refurbish or upgrade tritium extraction facilities; (b) extend the lives of heavy water reactors, or build new ones; (c) reduce tritium sales; (d) boost tritium production in the remaining heavy water reactors. All of the alternative production methods considered have serious economic and regulatory drawbacks, and the risk of diversion of tritium or lithium-6 would also be a major concern. There are likely to be serious problems with supplying tritium for future

  6. Kaiser Permanente/Sandia National health care model. Phase I prototype final report. Part 1 - model overview

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Edwards, D.; Yoshimura, A.; Butler, D.

    1996-11-01

    This report describes the results of a Cooperative Research and Development Agreement between Sandia National Laboratories and Kaiser Permanente Southern California to develop a prototype computer model of Kaiser Permanente`s health care delivery system. As a discrete event simulation, SimHCO models for each of 100,000 patients the progression of disease, individual resource usage, and patient choices in a competitive environment. SimHCO is implemented in the object-oriented programming language C++, stressing reusable knowledge and reusable software components. The versioned implementation of SimHCO showed that the object-oriented framework allows the program to grow in complexity in an incremental way. Furthermore, timing calculationsmore » showed that SimHCO runs in a reasonable time on typical workstations, and that a second phase model will scale proportionally and run within the system constraints of contemporary computer technology. This report is published as two documents: Model Overview and Domain Analysis. A separate Kaiser-proprietary report contains the Disease and Health Care Organization Selection Models.« less

  7. 75 FR 51499 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Digital I&C...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Digital I&C Systems The ACRS Subcommittee on Digital Instrumentation and Controls (I&C) Systems...: Wednesday, September 8, 2010--8:30 a.m. until 12 p.m. The Subcommittee will review Digital I&C Interim Staff...

  8. A prototype piecewise-linear dynamic attenuator

    NASA Astrophysics Data System (ADS)

    Hsieh, Scott S.; Peng, Mark V.; May, Christopher A.; Shunhavanich, Picha; Fleischmann, Dominik; Pelc, Norbert J.

    2016-07-01

    The piecewise-linear dynamic attenuator has been proposed as a mechanism in CT scanning for personalizing the x-ray illumination on a patient- and application-specific basis. Previous simulations have shown benefits in image quality, scatter, and dose objectives. We report on the first prototype implementation. This prototype is reduced in scale and speed and is integrated into a tabletop CT system with a smaller field of view (25 cm) and longer scan time (42 s) compared to a clinical system. Stainless steel wedges were machined and affixed to linear actuators, which were in turn held secure by a frame built using rapid prototyping technologies. The actuators were computer-controlled, with characteristic noise of about 100 microns. Simulations suggest that in a clinical setting, the impact of actuator noise could lead to artifacts of only 1 HU. Ring artifacts were minimized by careful design of the wedges. A water beam hardening correction was applied and the scan was collimated to reduce scatter. We scanned a 16 cm water cylinder phantom as well as an anthropomorphic pediatric phantom. The artifacts present in reconstructed images are comparable to artifacts normally seen with this tabletop system. Compared to a flat-field reference scan, increased detectability at reduced dose is shown and streaking is reduced. Artifacts are modest in our images and further refinement is possible. Issues of mechanical speed and stability in the challenging clinical CT environment will be addressed in a future design.

  9. Industri-Plex, OU-1, Master Cover Certification Report: Industri-Plex Site: September 30, 2008: Appendix C, C.1-C.2

    EPA Pesticide Factsheets

    2012-04-22

    ... Sincerely, \\ -/) I iJ/;5.~~.k. -r--7~.~~- ... 2.i:<c 0l.-'v<.. ';Q -v.....e. +r, f' ;; 0 J:'. \\- C\\. ~., S V"o€. n:: VcO-T :; I,....Ai'lZ G"'. .\\k (-lL0'-"- ,1....0L '\\0 ...

  10. Cocrystal assembled by 1,4-diiodotetrafluorobenzene and phenothiazine based on C-I...π/N/S halogen bond and other assisting interactions.

    PubMed

    Wang, Hui; Jin, Wei Jun

    2017-04-01

    The halogen-bonded cocrystal of 1,4-diiodotetrafluorobenzene (1,4-DITFB) with the butterfly-shape non-planar heterocyclic compound phenothiazine (PHT) was successfully assembled by the conventional solution-based method. X-ray single-crystal diffraction analysis reveals a 3:2 stoichiometric ratio for the cocrystal (1,4-DITFB/PHT), and the cocrystal structure is constructed via C-I...π, C-I...N and C-I...S halogen bonds as well as other assisting interactions (e.g. C-H...F/S hydrogen bond, C-H...H-C and C-F...F-C bonds). The small shift of the 1,4-DITFB vibrational band to lower frequencies in FT-IR and Raman spectroscopies provide evidence to confirm the existence of the halogen bond. In addition, the non-planarity of the PHT molecule in the cocrystal results in PHT emitting weak phosphorescence and relatively strong delayed fluorescence. Thus, a wide range of delayed fluorescence and weak phosphorescence could play a significant role in selecting a proper π-conjugated system to engineer functional cocrystal and luminescent materials by halogen bonds.

  11. MIRK/DYRK1B MEDIATES SURVIVAL DURING THE DIFFERENTIATION OF C2C12 MYOBLASTS 1

    PubMed Central

    Mercer, Stephen E.; Ewton, Daina Z.; Deng, Xiaobing; Lim, Seunghwan; Mazur, Thomas R.; Friedman, Eileen

    2005-01-01

    The kinase Mirk/dyrk1B is essential for the differentiation of C2C12 myoblasts. Mirk reinforces the G0/G1 arrest state in which differentiation occurs by directly phosphorylating and stabilizing p27kip1 and destabilizing cyclin D1. We now demonstrate that Mirk is anti-apoptotic in myoblasts. Knockdown of endogenous Mirk by RNA interference activated caspase 3 and decreased myoblast survival by 75%, while transient overexpression of Mirk increased cell survival. Mirk exerts its anti-apoptotic effects during muscle differentiation at least in part through effects on the cell cycle inhibitor and pro-survival molecule p21cip1. Overexpression and RNA interference experiments demonstrated that Mirk phosphorylates p21 within its nuclear localization domain at Ser153 causing a portion of the typically nuclear p21 to localize in the cytoplasm. Phosphomimetic GFP-p21-S153D was pancellular in both cycling C2C12 myoblasts and NIH3T3 cells. Endogenous Mirk in myotubes, and overexpressed Mirk in NIH3T3 cells were able to cause the pancellular localization of wild-type GFP-p21, but not the non-phosphorylatable mutant GFP-p21-S153A. Translocation to the cytoplasm enables p21 to block apoptosis through inhibitory interaction with pro-apoptotic molecules. Phosphomimetic p21-S153D was more effective than wild-type p21 in blocking the activation of caspase 3. Transient expression of p21-S153D also increased myoblast viability in colony forming assays, while the p21-S153A mutant had no effect. This Mirk-dependent change in p21 intracellular localization is a natural part of myoblast differentiation. Endogenous p21 localized exclusively to the nuclei of proliferating myoblasts, but was also found in the cytoplasm of post-mitotic multinucleated myotubes and adult human skeletal myofibers. PMID:15851482

  12. Integrated intelligent systems in advanced reactor control rooms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beckmeyer, R.R.

    1989-01-01

    An intelligent, reactor control room, information system is designed to be an integral part of an advanced control room and will assist the reactor operator's decision making process by continuously monitoring the current plant state and providing recommended operator actions to improve that state. This intelligent system is an integral part of, as well as an extension to, the plant protection and control systems. This paper describes the interaction of several functional components (intelligent information data display, technical specifications monitoring, and dynamic procedures) of the overall system and the artificial intelligence laboratory environment assembled for testing the prototype. 10 refs.,more » 5 figs.« less

  13. Nuclear reactors built, being built, or planned 1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-08-01

    This publication contains unclassified information about facilities, built, being built, or planned in the United States for domestic use or export as of December 31, 1996. The Office of Scientific and Technical Information, U.S. Department of Energy, gathers this information annually from Washington headquarters, and field offices of DOE; from the U.S. Nuclear Regulatory Commission (NRC); from the U. S. reactor manufacturers who are the principal nuclear contractors for foreign reactor locations; from U.S. and foreign embassies; and from foreign governmental nuclear departments. The book consists of three divisions, as follows: (1) a commercial reactor locator map and tables ofmore » the characteristic and statistical data that follow; a table of abbreviations; (2) tables of data for reactors operating, being built, or planned; and (3) tables of data for reactors that have been shut down permanently or dismantled.« less

  14. WILL COMET ISON (C/2012 S1) SURVIVE PERIHELION?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Knight, Matthew M.; Walsh, Kevin J., E-mail: knight@lowell.edu

    2013-10-10

    On 2013 November 28 Comet ISON (C/2012 S1) will pass by the Sun with a perihelion distance of 2.7 solar radii. Understanding the possible outcomes for the comet's response to such a close passage by the Sun is important for planning observational campaigns and for inferring ISON's physical properties. We present new numerical simulations and interpret them in context with the historical track record of comet disruptions and of sungrazing comet behavior. Historical data suggest that sizes below ∼200 m are susceptible to destruction by sublimation driven mass loss, while we find that for ISON's perihelion distance, densities lower thanmore » 0.1 g cm{sup –3} are required to tidally disrupt a retrograde or non-spinning body. Such low densities are substantially below the range of the best-determined comet nucleus densities, though dynamically new comets such as ISON have few measurements of physical properties. Disruption may occur for prograde rotation at densities up to 0.7 g cm{sup –3}, with the chances of disruption increasing for lower density, faster prograde rotation, and increasing elongation of the nucleus. Given current constraints on ISON's nucleus properties and the typically determined values for these properties among all comets, we find tidal disruption to be unlikely unless other factors (e.g., spin-up via torquing) affect ISON substantially. Whether or not disruption occurs, the largest remnant must be big enough to survive subsequent mass loss due to sublimation in order for ISON to remain a viable comet well after perihelion.« less

  15. Health physics aspects of advanced reactor licensing reviews

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hinson, C.S.

    1995-03-01

    The last Construction Permit to be issued by the U.S. Nuclear Regulatory Commission (NRC) for a U.S. light water reactor (LWR) was granted in the late 1970s. In 1989 the NRC issued 10 CFR Part 52 which is intended to serve as a framework for the licensing of future reactor designs. The NRC is currently reviewing four different future on {open_quotes}next-generation{close_quotes} reactor designs. Two of these designs are classified as evolutionary designs (modified versions of current generation LWRs) and two are advanced designs (reactors incorporating simplified designs and passive means for accident mitigation). These {open_quotes}next-generation{close_quotes} reactor designs incorporate many innovativemore » design features which are intended to maintain personnel doses ALARA and ensure that the annual average collective dose at these reactors does not exceed 100 person-rems (1 person-sievert) per year. This paper discusses some of the ALARA design features which are incorporated in the four {open_quotes}next-generation{close_quotes} reactor designs incorporate many innovative design features which are intended to maintain personnel doses ALARA and ensure that the annual average collective dose at these reactors does not exceed 100 person-rems (1 person-sievert) per year. This paper discusses some of the ALARA design features which are incorporated in the four {open_quotes}next-generation{close_quotes} reactor designs currently being reviewed by the NRC.« less

  16. A search for neutrino oscillations using the CHOOZ 1 km baseline reactor neutrino experiment

    NASA Astrophysics Data System (ADS)

    George, Jean

    1999-10-01

    Neutrino oscillation searches are an active field of research due to the implications their discovery may have for the solar neutrino anomaly as well as for the atmospheric neutrino anomaly. Their discovery may also have broad ramifications for the Standard Model of Particle Physics as a whole. Results from an oscillation search using the CHOOZ long baseline reactor neutrino experiment are presented in this thesis. These results are based on the data taken from June 1997 through April 1998 when the two reactors ran at combined thermal power levels ranging from zero power to their full power level of 8.5 GW. Electron flavored antineutrinos emanating from the reactors were detected through the inverse beta decay channel using a liquid scintillating calorimeter located at a distance of approximately 1 km from the reactor sources. The underground experimental site (300 MWE) provided natural shielding from the background of cosmic ray muons-leading to a background rate more than an order of magnitude lower than the full power signal rate. From the agreement between the detected and expected neutrino event rates no evidence for neutrino oscillations was found (at the 90% C.L.) for the oscillation parameter space governed by Δm 2 > 0.8 × 10-3 eV2 for maximal mixing and by sin2 2Θ > 0.18 for large values of Δm2.

  17. 40-MW(E) PROTOTYPE HIGH-TEMPERATURE GAS-COOLED REACTOR RESEARCH AND DEVELOPMENT PROGRAM. Quarterly Progress Report for the Period Ending June 30, 1962

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1963-10-31

    Research and development progress specifically directed toward the construction of a 40-Mw(e) prototype power plant employing a high-temperature, gas-cooled, graphitemoderated reactor known as the HTGR is reported. Irradiation of element III-B in the in-pile loop continued satisfactorily. The element has generated a total of l36.3 Mw-hr of fission heat. The gross activity in the purge stream increased slightly to about 350 mu C/cm/sup 3/. By taking larger gas samples than were previously taken, a value of 0.02 VC/cm/sup 3/ was obtained for the gross activity of the primary loop. Element III-A, which was removed from the loop after generating 133more » Mw-hr of fission heat, was disassembled and examined. No fuel-compact damage of any type was visible. Determination of the distribution of fission products in the element is under way, Fissionproduct- release data for in-pile-loop element III-A were calculated. During the 133 Mw- hr of operation, the release fraction increased by approximately one order of magnitude. Also calculated were the xenon and krypton release data for the first 100 Mw-hr of III-B operation. The release rate for the longer-lived isotopes increased bv about a factor of 10 and that of the shorter-lived isotopes by about a factor of 100. A test was run in which the in-pileloop purge flow, was stopped. The primariy-loop activity level rose sharply during the first hour, increased at a slower rate for the next 11 hr, and then appeared to level off. When purge flow was resumed, the gross activity in the primary loop was cleaned up with a half life of about 2.2 hr. An attempt was made to identify Cs/sup 137/ and Ba/ sup 140/ plateout in portions of the in-pile loop. A very small amount of cesium (less than a monolayer) was found, but no barium could be detected. The validity of two basic assumptions made in the one-dimensional burnup code FEVER was investigated. As a result of extensive lifetime studies and power-distribution and

  18. Design of boron carbide-shielded irradiation channel of the outer irradiation channel of the Ghana Research Reactor-1 using MCNP.

    PubMed

    Abrefah, R G; Sogbadji, R B M; Ampomah-Amoako, E; Birikorang, S A; Odoi, H C; Nyarko, B J B

    2011-01-01

    The MCNP model for the Ghana Research Reactor-1 was redesigned to incorporate a boron carbide-shielded irradiation channel in one of the outer irradiation channels. Extensive investigations were made before arriving at the final design of only one boron carbide covered outer irradiation channel; as all the other designs that were considered did not give desirable results of neutronic performance. The concept of redesigning a new MCNP model, which has a boron carbide-shielded channel is to equip the Ghana Research Reactor-1 with the means of performing efficient epithermal neutron activation analysis. After the simulation, a comparison of the results from the original MCNP model for the Ghana Research Reactor-1 and the new redesigned model of the boron carbide shielded channel was made. The final effective criticality of the original MCNP model for the GHARR-1 was recorded as 1.00402 while that of the new boron carbide designed model was recorded as 1.00282. Also, a final prompt neutron lifetime of 1.5245 × 10(-4)s was recorded for the new boron carbide designed model while a value of 1.5571 × 10(-7)s was recorded for the original MCNP design of the GHARR-1. Copyright © 2010 Elsevier Ltd. All rights reserved.

  19. In service inspection and repair of sodium cooled ASTRID prototype

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baque, F.; Jadot, F.; Marlier, R.

    2015-07-01

    In the frame of the large R and D work which is performed for the future ASTRID sodium cooled prototype, In Service Inspection and Repair (ISI and R) has been identified as a major issue to be taken into account in order to enlarge the plant safety, to consolidate its availability and to protect the associated investment. After the first part of pre-conceptual design phase (2008-2012), the running second part of pre-conceptual phase (2013-2015) allows to increase the ISI and R tool ability for immersed sodium structures of ASTRID, at about 200 deg. C, on the basis of consolidated specificationsmore » and thanks to their qualification through more and more realistic laboratory tests and simulation with CIVA code. ISI and R items are being developed and qualified during a pluri-annual program which mainly deals with the reactor block structures, the primary components and circuit, and the Power Conversion System. It ensures a strong connection between the reactor designers and inspection specialists, as the optimization of inspectability and repairability is looked at: this already induced specific rules for design, in order to shorten and ease the ISI and R operations, which have been merged into RCC-MRx rules. In the frame of increasing technology readiness level with corresponding performance demonstration, this paper presents R and D dealing with the ISI and R items: it highlights the sensor development (both ultrasonic and electromagnetic concepts, compatible with sodium at 200 deg. C), then their applications for ASTRID structure control (under sodium telemetry, imaging and NDE). Activity for repair is also presented (a single laser tool for sodium sweeping, machining and welding), and finally the effort for associated robotic (generic program for ASTRID applications, specific technological tools for sodium medium, tight immersed bell). The main results of testing and simulation are given for telemetry, vision, NDE applications, laser process repair and under

  20. Ghana watershed prototype products

    USGS Publications Warehouse

    ,

    2007-01-01

    A number of satellite data sets are available through the U.S. Geological Survey (USGS) for monitoring land surface features. Representative data sets include Landsat, Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER), and Shuttle Radar Topography Mission (SRTM). The Ghana Watershed Prototype Products cover an area within southern Ghana, Africa, and include examples of the aforementioned data sets along with sample SRTM derivative data sets.

  1. Structural analysis of the starfish SALMFamide neuropeptides S1 and S2: the N-terminal region of S2 facilitates self-association.

    PubMed

    Otara, Claire B; Jones, Christopher E; Younan, Nadine D; Viles, John H; Elphick, Maurice R

    2014-02-01

    The neuropeptides S1 (GFNSALMFamide) and S2 (SGPYSFNSGLTFamide), which share sequence similarity, were discovered in the starfish Asterias rubens and are prototypical members of the SALMFamide family of neuropeptides in echinoderms. SALMFamide neuropeptides act as muscle relaxants and both S1 and S2 cause relaxation of cardiac stomach and tube foot preparations in vitro but S2 is an order of magnitude more potent than S1. Here we investigated a structural basis for this difference in potency using spectroscopic techniques. Circular dichroism spectroscopy showed that S1 does not have a defined structure in aqueous solution and this was supported by 2D nuclear magnetic resonance experiments. In contrast, we found that S2 has a well-defined conformation in aqueous solution. However, the conformation of S2 was concentration dependent, with increasing concentration inducing a transition from an unstructured to a structured conformation. Interestingly, this property of S2 was not observed in an N-terminally truncated analogue of S2 (short S2 or SS2; SFNSGLTFamide). Collectively, the data obtained indicate that the N-terminal region of S2 facilitates peptide self-association at high concentrations, which may have relevance to the biosynthesis and/or bioactivity of S2 in vivo. © 2013.

  2. Enrichment of acetogenic bacteria in high rate anaerobic reactors under mesophilic and thermophilic conditions.

    PubMed

    Ryan, P; Forbes, C; McHugh, S; O'Reilly, C; Fleming, G T A; Colleran, E

    2010-07-01

    The objective of the current study was to expand the knowledge of the role of acetogenic Bacteria in high rate anaerobic digesters. To this end, acetogens were enriched by supplying a variety of acetogenic growth supportive substrates to two laboratory scale high rate upflow anaerobic sludge bed (UASB) reactors operated at 37 degrees C (R1) and 55 degrees C (R2). The reactors were initially fed a glucose/acetate influent. Having achieved high operational performance and granular sludge development and activity, both reactors were changed to homoacetogenic bacterial substrates on day 373 of the trial. The reactors were initially fed with sodium vanillate as a sole substrate. Although % COD removal indicated that the 55 degrees C reactor out performed the 37 degrees C reactor, effluent acetate levels from R2 were generally higher than from R1, reaching values as high as 5023 mg l(-1). Homoacetogenic activity in both reactors was confirmed on day 419 by specific acetogenic activity (SAA) measurement, with higher values obtained for R2 than R1. Sodium formate was introduced as sole substrate to both reactors on day 464. It was found that formate supported acetogenic activity at both temperatures. By the end of the trial, no specific methanogenic activity (SMA) was observed against acetate and propionate indicating that the methane produced was solely by hydrogenotrophic Archaea. Higher SMA and SAA values against H(2)/CO(2) suggested development of a formate utilising acetogenic population growing in syntrophy with hydrogenotrophic methanogens. Throughout the formate trial, the mesophilic reactor performed better overall than the thermophilic reactor. Copyright 2010 Elsevier Ltd. All rights reserved.

  3. [Investigation of bacterial diversity in the biological desulfurization reactor for treating high salinity wastewater by the 16S rDNA cloning method].

    PubMed

    Liu, Wei-Guo; Liang, Cun-Zhen; Yang, Jin-Sheng; Wang, Gui-Ping; Liu, Miao-Miao

    2013-02-01

    The bacterial diversity in the biological desulfurization reactor operated continuously for 1 year was studied by the 16S rDNA cloning and sequencing method. Forty clones were randomly selected and their partial 16S rDNA genes (ca. 1,400 bp) were sequenced and blasted. The results indicated that there were dominant bacterias in the biological desulfurization reactor, where 33 clones belonged to 3 different published phyla, while 1 clone belonged to unknown phylum. The dominant bacterial community in the system was Proteobacteria, which accounted for 85.3%. The bacterial community succession was as follows: the gamma-Proteobacteria(55.9%), beta-Proteobacteria(17.6%), Actinobacteridae (8.8%), delta-Proteobacteria (5.9%) , alpha-Proteobacteria(5.9%), and Sphingobacteria (2.9%). Halothiobacillus sp. ST15 and Thiobacillus sp. UAM-I were the major desulfurization strains.

  4. Flavonoids from the grains of C1/R-S transgenic rice, the transgenic Oryza sativa spp. japonica, and their radical scavenging activities.

    PubMed

    Cho, Jin-Gyeong; Song, Na-Young; Nam, Tae-Gyu; Shrestha, Sabina; Park, Hee-Jung; Lyu, Ha-Na; Kim, Dae-Ok; Lee, Gihwan; Woo, Young-Min; Jeong, Tae-Sook; Baek, Nam-In

    2013-10-30

    The transgenic rice cultivar of Oryza sativa spp. japonica cv. Hwa-Young, C1/R-S transgenic rice (C1/R-S rice), is a flavonoid-rich cultivar of rice. The grains of C1/R-S rice were extracted with aqueous MeOH, and the concentrated extract was partitioned with EtOAc, n-BuOH, and H2O, successively. Repeated silica gel, octadecyl silica gel (ODS), and Sephadex LH-20 column chromatographies for the EtOAc and n-BuOH fractions afforded four new flavonoids (compounds 2, 3, 7, and 8) along with four known flavonoids: (+)-3'-O-methyltaxifolin (1), brassicin (4), isorhamnetin-4'-O-β-D-glucosyranoside (5), and 3'-O-methyltaxifolin-5-O-β-D-glucopyranoside (6). The new flavonoids were identified as 3'-O-methyltaxifolin-7-O-β-D-glucopyranoside (2), 3'-O-methyltaxifolin-4'-O-β-D-glucopyranoside (3), isorhamnetin-7-O-β-D-cellobioside (brassicin-4″-O-β-D-glucopyranoside) (7), and brassicin-4'-O-β-D-glucosyranoside (8) from the result of spectroscopic data including nuclear magnetic resonance spectrometry (NMR), mass spectrometry (MS), and infrared spectroscopy (IR). Also, quantitative analysis of major flavonoids (compounds 2, 3, and 8) in C1/R-S rice, O. sativa spp. japonica cv. Hwa-Young (HY), and a hybrid of two cultivar (C1/R-S rice/HY) extracts was performed using HPLC experiment. The isolated flavonoids were evaluated for their radical-scavenging effect on DPPH and ABTS radicals.

  5. Isomerization, Perturbations, Calculations and the S_{1} State of C_{2}H_{2}

    NASA Astrophysics Data System (ADS)

    Baraban, J. H.; Changala, P. B.; Berk, J. R. P.; Field, R. W.; Stanton, J. F.; Merer, A. J.

    2013-06-01

    Preliminary analysis of the energy region of the cis-trans isomerization transition state on the S_{1} surface of C_{2}H_{2} has revealed novel patterns and surprising perturbations, including unusually large (and high-order) anharmonicities, as well as K-staggerings of several vibrational levels. These effects complicate the analysis considerably, and require new models and calculations to account for and predict features of the observed spectra. The ˜{A}-˜{X} spectrum of acetylene has been studied both experimentally and theoretically for almost a century, and this cycle of unexpected phenomena eliciting innovative responses is found throughout its history. Especially in the last ten years, progress in understanding the S_{1} state rovibrational level structure and cis-trans isomerization has been accelerated by combining the information available from both ab initio computation and spectroscopic observations. The resulting dialogue has then frequently suggested fruitful avenues for further experiments and calculations. Current challenges and recent results in understanding the cis-trans isomerization transition state region will be discussed in this context.

  6. MODIFIED N.R.C. VERSION OF THE U.S.G.S. SOLUTE TRANSPORT MODEL. VOLUME 1. MODIFICATIONS

    EPA Science Inventory

    The methods described in the report can be used with the modified N.R.C. version of the U.S.G.S. Solute Transport Model to predict the concentration of chemical parameters in a contaminant plume. The two volume report contains program documentation and user's manual. The program ...

  7. NEET Enhanced Micro-Pocket Fission Detector for High Temperature Reactors - FY16 Status Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Unruh, Troy; Reichenberger, Michael; Stevenson, Sarah

    2016-09-01

    A collaboration between the Idaho National Laboratory (INL), the Kansas State University (KSU), and the French Atomic Energy Agency, Commissariat à l'Énergie Atomique et aux Energies Alternatives, (CEA), has been initiated by the Nuclear Energy Enabling Technologies (NEET) Advanced Sensors and Instrumentation (ASI) program for developing and testing High Temperature Micro-Pocket Fission Detectors (HT MPFD), which are compact fission chambers capable of simultaneously measuring thermal neutron flux, fast neutron flux and temperature within a single package for temperatures up to 800 °C. The MPFD technology utilizes a small, multi-purpose, robust, in-core fission chambers and thermocouple. As discussed within this report,more » the small size, variable sensitivity, and increased accuracy of the MPFD technology represent a revolutionary improvement over current methods used to support irradiations in US Material Test Reactors (MTRs). Previous research conducted through NEET ASI1-3 has shown that the MPFD technology could be made robust and was successfully tested in a reactor core. This new project will further the MPFD technology for higher temperature regimes and other reactor applications by developing a HT MPFD suitable for temperatures up to 800 °C. This report summarizes the research progress for year two of this three year project. Highlights from research accomplishments include: • Continuation of a joint collaboration between INL, KSU, and CEA. Note that CEA is participating at their own expense because of interest in this unique new sensor. • An updated parallel wire HT MPFD design was developed. • Program support for HT MPFD deployments was given to Accident Tolerant Fuels (ATF) and Advanced Gas-cooled Reactor (AGR) irradiation test programs. • Quality approved materials for HT MPFD construction were procured by irradiation test programs for upcoming deployments. • KSU improved and performed electrical contact and fissile material plating.

  8. A Blueprint for GNEP Advanced Burner Reactor Startup Fuel Fabrication Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    S. Khericha

    2010-12-01

    The purpose of this article is to identify the requirements and issues associated with design of GNEP Advanced Burner Reactor Fuel Facility. The report was prepared in support of providing data for preparation of a NEPA Environmental Impact Statement in support the U. S. Department of Energy (DOE) Global Nuclear Energy Partnership (GNEP). One of the GNEP objectives was to reduce the inventory of long lived actinide from the light water reactor (LWR) spent fuel. The LWR spent fuel contains Plutonium (Pu) -239 and other transuranics (TRU) such as Americium-241. One of the options is to transmute or burn thesemore » actinides in fast neutron spectra as well as generate the electricity. A sodium-cooled Advanced Recycling Reactor (ARR) concept was proposed to achieve this goal. However, fuel with relatively high TRU content has not been used in the fast reactor. To demonstrate the utilization of TRU fuel in a fast reactor, an Advanced Burner Reactor (ABR) prototype of ARR was proposed, which would necessarily be started up using weapons grade (WG) Pu fuel. The WG Pu is distinguished by relatively highest proportions of Pu-239 and lesser amount of other actinides. The WG Pu was assumed to be used as the startup fuel along with TRU fuel in lead test assemblies. Because such fuel is not currently being produced in the US, a new facility (or new capability in an existing facility) was being considered for fabrication of WG Pu fuel for the ABR. It was estimated that the facility will provide the startup fuel for 10-15 years and would take 3 to 5 years to construct.« less

  9. Word Frequency Analysis. MOS: 51C. Skill Levels 1 & 2.

    DTIC Science & Technology

    1981-05-01

    FF-TCR1NG I RESTS 2 RESULT I RESJLTS I VETA I NS 3 it 0Up N I R~vERS-1L. I F E VtS ZNG I PEVELVIKG MOS WORDo LISTINGASCENDIIG SECUEME C.ATE 93259 t39...1 0 J CACCUPULATEG 1 J fiCID I * ?L4CoS 1 j & T.CrC$S 2 0 J tAnJUSTASLE I J rC.Ff ER 8 J E .11:-COflOITIOING 5 *J CALL 1 0 J LALLOM I J (A~LLOW~S 4 *J...ALCMj 3 *J &:.L" VS 1 0 3 12 0 j ...’Jo I *J W Git Z I ., 1 4 J fNVIL I ’ . lUV I J E C.PPEAJRS I I J E .*,PL! CATION 2 2 C. PPLY I 3 C.;PPPtovEo a 3

  10. A novel approach for toluene gas treatment using a downflow hanging sponge reactor.

    PubMed

    Yamaguchi, Tsuyoshi; Nakamura, Syoichiro; Hatamoto, Masashi; Tamura, Eisuke; Tanikawa, Daisuke; Kawakami, Shuji; Nakamura, Akinobu; Kato, Kaoru; Nagano, Akihiro; Yamaguchi, Takashi

    2018-05-01

    A novel gas-scrubbing bioreactor based on a downflow hanging sponge (DHS) reactor was developed as a new volatile organic compound (VOC) treatment system. In this study, the effects of varying the space velocity and gas/liquid ratio were investigated to assess the effectiveness of using toluene gas as a model VOC. Under optimal conditions, the toluene removal rate was greater than 80%, and the maximum elimination capacity was observed at approximately 13 g-C m -3  h -1 . The DHS reactor demonstrated slight pressure loss (20 Pa) and a high concentration of suspended solids (up to 30,000 mg/L-sponge). Cloning analysis of the 16S rRNA and functional genes of toluene degradation pathways (tmoA, todC, tbmD, xylA, and bssA) revealed that the clones belonging to the toluene-degrading bacterium Pseudomonas putida constituted the predominant species detected at the bottom of the DHS reactor. The toluene-degrading bacteria Pseudoxanthomonas spadix and Pseudomonas sp. were also detected by tmoA- and todC-targeted cloning analyses, respectively. These results demonstrate the potential for the industrial application of this novel DHS reactor for toluene gas treatment.

  11. Engineering Porous Polymer Hollow Fiber Microfluidic Reactors for Sustainable C-H Functionalization.

    PubMed

    He, Yingxin; Rezaei, Fateme; Kapila, Shubhender; Rownaghi, Ali A

    2017-05-17

    Highly hydrophilic and solvent-stable porous polyamide-imide (PAI) hollow fibers were created by cross-linking of bare PAI hollow fibers with 3-aminopropyl trimethoxysilane (APS). The APS-grafted PAI hollow fibers were then functionalized with salicylic aldehyde for binding catalytically active Pd(II) ions through a covalent postmodification method. The catalytic activity of the composite hollow fiber microfluidic reactors (Pd(II) immobilized APS-grafted PAI hollow fibers) was tested via heterogeneous Heck coupling reaction of aryl halides under both batch and continuous-flow reactions in polar aprotic solvents at high temperature (120 °C) and low operating pressure. X-ray photoelectron spectroscopy (XPS) and inductively coupled plasma (ICP) analyses of the starting and recycled composite hollow fibers indicated that the fibers contain very similar loadings of Pd(II), implying no degree of catalyst leaching from the hollow fibers during reaction. The composite hollow fiber microfluidic reactors showed long-term stability and strong control over the leaching of Pd species.

  12. 38 CFR 8.1 - Effective date for an insurance policy issued under section 1922(a) of title 38 U.S.C. (Service...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Effective date for an insurance policy issued under section 1922(a) of title 38 U.S.C. (Service-Disabled Veterans' Insurance). 8.1... 38 U.S.C. (Service-Disabled Veterans' Insurance). (a) What is the effective date of the policy? The...

  13. 38 CFR 8.1 - Effective date for an insurance policy issued under section 1922(a) of title 38 U.S.C. (Service...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Effective date for an insurance policy issued under section 1922(a) of title 38 U.S.C. (Service-Disabled Veterans' Insurance). 8.1... 38 U.S.C. (Service-Disabled Veterans' Insurance). (a) What is the effective date of the policy? The...

  14. 38 CFR 8.1 - Effective date for an insurance policy issued under section 1922(a) of title 38 U.S.C. (Service...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false Effective date for an insurance policy issued under section 1922(a) of title 38 U.S.C. (Service-Disabled Veterans' Insurance). 8.1... 38 U.S.C. (Service-Disabled Veterans' Insurance). (a) What is the effective date of the policy? The...

  15. 38 CFR 8.1 - Effective date for an insurance policy issued under section 1922(a) of title 38 U.S.C. (Service...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Effective date for an insurance policy issued under section 1922(a) of title 38 U.S.C. (Service-Disabled Veterans' Insurance). 8.1... 38 U.S.C. (Service-Disabled Veterans' Insurance). (a) What is the effective date of the policy? The...

  16. 38 CFR 8.1 - Effective date for an insurance policy issued under section 1922(a) of title 38 U.S.C. (Service...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Effective date for an insurance policy issued under section 1922(a) of title 38 U.S.C. (Service-Disabled Veterans' Insurance). 8.1... 38 U.S.C. (Service-Disabled Veterans' Insurance). (a) What is the effective date of the policy? The...

  17. The LANDFIRE Prototype Project: nationally consistent and locally relevant geospatial data for wildland fire management

    Treesearch

    Matthew G. Rollins; Christine K. Frame

    2006-01-01

    The Landscape Fire and Resource Management Planning Tools Prototype Project, or LANDFIRE Prototype Project, began in April of 2002 and ended in April of 2005. The project was funded by the U.S. Department of Agriculture Forest Service and U.S. Department of the Interior. The objectives of the LANDFIRE Prototype Project were to develop the methods, tools, and protocols...

  18. An Experimental Examination of the Loss-of-Flow Accident Phenomenon for Prototypical ITER Divertor Channels of Y = 0 and Y = 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marshall, Theron D.; McDonald, Jimmie M.; Cadwallader, Lee C.

    2000-01-15

    This paper discusses the thermal response of two prototypical International Thermonuclear Experimental Reactor (ITER) divertor channels during simulated loss-of-flow-accident (LOFA) experiments. The thermal response was characterized by the time-to-burnout (TBO), which is a figure of merit on the mockups' survivability. Data from the LOFA experiments illustrate that (a) the pre-LOFA inlet velocity does not significantly influence the TBO, (b) the incident heat flux (IHF) does influence the TBO, and (c) a swirl tape insert significantly improves the TBO and promotes the initiation of natural circulation. This natural circulation enabled the mockup to absorb steady-state IHFs after the coolant circulation pumpmore » was disabled. Several methodologies for thermal-hydraulic modeling of the LOFA were attempted.« less

  19. An experimental examination of the loss-of-flow accident phenomenon for prototypical ITER divertor channels of Y=0 and Y=2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marshall, T.D.; McDonald, J.M.; Cadwallader, L.C.

    2000-01-01

    This paper discusses the thermal response of two prototypical International Thermonuclear Experimental Reactor (ITER) divertor channels during simulated loss-of-flow-accident (LOFA) experiments. The thermal response was characterized by the time-to-burnout (TBO), which is a figure of merit on the mockups' survivability. Data from the LOFA experiments illustrate that (a) the pre-LOFA inlet velocity does not significantly influence the TBO, (b) the incident heat flux (IHF) does influence the TBO, and (c) a swirl tape insert significantly improves the TBO and promotes the initiation of natural circulation. This natural circulation enabled the mockup to absorb steady-state IHFs after the coolant circulation pumpmore » was disabled. Several methodologies for thermal-hydraulic modeling of the LOFA were attempted.« less

  20. [Kinetics of catalytic wet air oxidation of phenol in trickle bed reactor].

    PubMed

    Li, Guang-ming; Zhao, Jian-fu; Wang, Hua; Zhao, Xiu-hua; Zhou, Yang-yuan

    2004-05-01

    By using a trickle bed reactor which was designed by the authors, the catalytic wet air oxidation reaction of phenol on CuO/gamma-Al2O3 catalyst was studied. The results showed that in mild operation conditions (at temperature of 180 degrees C, pressure of 3 MPa, liquid feed rate of 1.668 L x h(-1) and oxygen feed rate of 160 L x h(-1)), the removal of phenol can be over 90%. The curve of phenol conversion is similar to "S" like autocatalytic reaction, and is accordance with chain reaction of free radical. The kinetic model of pseudo homogenous reactor fits the catalytic wet air oxidation reaction of phenol. The effects of initial concentration of phenol, liquid feed rate and temperature for reaction also were investigated.

  1. Nuclear propulsion apparatus with alternate reactor segments

    DOEpatents

    Szekely, Thomas

    1979-04-03

    1. Nuclear propulsion apparatus comprising: A. means for compressing incoming air; B. nuclear fission reactor means for heating said air; C. means for expanding a portion of the heated air to drive said compressing means; D. said nuclear fission reactor means being divided into a plurality of radially extending segments; E. means for directing a portion of the compressed air for heating through alternate segments of said reactor means and another portion of the compressed air for heating through the remaining segments of said reactor means; and F. means for further expanding the heated air from said drive means and the remaining heated air from said reactor means through nozzle means to effect reactive thrust on said apparatus.

  2. The Full-Scale Prototype for the Fluorescence Detector Array of Single-Pixel Telescopes

    NASA Astrophysics Data System (ADS)

    Fujii, T.; Malacari, M.; Bellido, J. A.; Farmer, J.; Galimova, A.; Horvath, P.; Hrabovsky, M.; Mandat, D.; Matalon, A.; Matthews, J. N.; Merolle, M.; Ni, X.; Nozka, L.; Palatka, M.; Pech, M.; Privitera, P.; Schovanek, P.; Thomas, S. B.; Travnicek, P.

    The Fluorescence detector Array of Single-pixel Telescopes (FAST) is a design concept for the next generation of ultrahigh-energy cosmic ray (UHECR) observatories, addressing the requirements for a large-area, low-cost detector suitable for measuring the properties of the highest energy cosmic rays. In the FAST design, a large field of view is covered by a few pixels at the focal plane of a mirror or Fresnel lens. Motivated by the successful detection of UHECRs using a prototype comprised of a single 200 mm photomultiplier-tube and a 1 m2 Fresnel lens system, we have developed a new "full-scale" prototype consisting of four 200 mm photomultiplier-tubes at the focus of a segmented mirror of 1.6 m in diameter. We report on the status of the full-scale prototype, including test measurements made during first light operation at the Telescope Array site in central Utah, U.S.A.

  3. Power API Prototype

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2014-12-04

    The software serves two purposes. The first purpose of the software is to prototype the Sandia High Performance Computing Power Application Programming Interface Specification effort. The specification can be found at http://powerapi.sandia.gov . Prototypes of the specification were developed in parallel with the development of the specification. Release of the prototype will be instructive to anyone who intends to implement the specification. More specifically, our vendor collaborators will benefit from the availability of the prototype. The second is in direct support of the PowerInsight power measurement device, which was co-developed with Penguin Computing. The software provides a cluster wide measurementmore » capability enabled by the PowerInsight device. The software can be used by anyone who purchases a PowerInsight device. The software will allow the user to easily collect power and energy information of a node that is instrumented with PowerInsight. The software can also be used as an example prototype implementation of the High Performance Computing Power Application Programming Interface Specification.« less

  4. 65. ARAII. Interior view of SL1 reactor building control piping ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    65. ARA-II. Interior view of SL-1 reactor building control piping for water purification system. On operating floor of building. March 21, 1958. Ineel photo no. 58-1360. Photographer: Jack L. Anderson. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  5. Microneedle Device Prototype

    DTIC Science & Technology

    2014-05-01

    Defense Threat Reduction Agency Research and Development Counter WMD Technologies Test Support Division 1680 Texas Street SE Kirtland AFB, NM...Device Prototype Final Report iv | List of Figures List of Figures Figure 3-1. Print screen of the STL file of a hollow microneedle design in Alibre...electrochemical characterization of gold electrode (n = 8) array with oxide dielectric defined working electrodes with 1 mM [Fe(CN)6] 3- in 0.1 M potassium

  6. Application of 1D and 2D MFR reactor technology for the isolation of insecticidal and anti-microbial properties from pyrolysis bio-oils.

    PubMed

    Hossain, Mohammad M; Scott, Ian M; Berruti, Franco; Briens, Cedric

    2016-12-01

    Valuable chemicals can be separated from agricultural residues by chemical or thermochemical processes. The application of pyrolysis has already been demonstrated as an efficient means to produce a liquid with a high concentration of desired product. The objective of this study was to apply an insect and microorganism bioassay-guided approach to separate and isolate pesticidal compounds from bio-oil produced through biomass pyrolysis. Tobacco leaf (Nicotianata bacum), tomato plant (Solanum lycopersicum), and spent coffee (Coffea arabica) grounds were pyrolyzed at 10°C/min from ambient to 565°C using the mechanically fluidized reactor (MFR). With one-dimensional (1D) MFR pyrolysis, the composition of the product vapors varied as the reactor temperature was raised allowing for the selection of the temperature range that corresponds to vapors with a high concentration of pesticidal properties. Further product separation was performed in a fractional condensation train, or 2D MFR pyrolysis, thus allowing for the separation of vapor components according to their condensation temperature. The 300-400°C tobacco and tomato bio-oil cuts from the 1D MFR showed the highest insecticidal and anti-microbial activity compared to the other bio-oil cuts. The 300-350 and 350-400°C bio-oil cuts produced by 2D MFR had the highest insecticidal activity when the bio-oil was collected from the 210°C condenser. The tobacco and tomato bio-oil had similar insecticidal activity (LC 50 of 2.1 and 2.2 mg/mL) when the bio-oil was collected in the 210°C condenser from the 300-350°C reactor temperature gases. The 2D MFR does concentrate the pesticidal products compared to the 1D MFR and thus can reduce the need for further separation steps such as solvent extraction.

  7. Complete ISOPHOT (C200) Maps of a Nearby Prototypical GMC: W3 (Spring) or NGC7538 (Fall)

    NASA Technical Reports Server (NTRS)

    Sanders, David B.

    2001-01-01

    We were originally awarded Priority 3 time (approximately 60,000 sec) with Infrared Space Observatory (ISO) to obtain a complete ISOPHOT (PHT32-C200) map of a nearby prototypical giant molecular cloud (GMC). Following the FALL launch and revised estimates for the sensitivity of the ISOPHOT detectors, our program was modified to fit within the time constraints while still carrying out the main science requirements. The revised program requested long strip maps of our FALL target (NGC7538) using sequences of PHT37/38/39 observations with LWS observations of the brightest regions. The large number of AOTs required to cover each GMC required that our observations be spread over four separate proposals (PROP-01, PROP-02, PROP-03, PROP-04) which together comprise a single observing program. Our program was executed in early 1997; nearly 50,000 sec of data were obtained, including all of our requested ISOPHOT C200 observations. None of the LWS data were taken.

  8. Evaporation Mechanism of Cu from Liquid Fe Containing C and S

    NASA Astrophysics Data System (ADS)

    Jung, Sung-Hoon; Kang, Youn-Bae

    2016-08-01

    A number of liquid-gas experiments were carried out in order to elucidate evaporation mechanism of Cu from liquid Fe containing C and S. Rate of Cu evaporation in liquid Fe droplets at 1873 K (1600 °C) was determined using electromagnetic levitation equipment. Evaporation rate of the Cu under various conditions (flow rate of gas mixtures, initial C, and S concentrations) was examined. It was found from a series of kinetic analyses of the experimental data that Cu evaporates in forms of Cu(g) and CuS(g). As was reported for the Sn evaporation from liquid iron (Jung et al. Met. Mater. Trans. 46B, 250-258, 2014), S plays two roles for the evaporation of Cu: accelerating the rate by forming CuS(g) and decelerating the rate by blocking evaporation sites. As a result of these combinatorial effects, the evaporation of Cu is decelerated at low S content, but is accelerated at high S content. Based on the elucidated mechanism, an evaporation model equation for Cu was developed in the present study, which takes into account (1) evaporation of Cu in the two forms (Cu(g) and CuS(g)), (2) surface blocking by S using ideal Langmuir adsorption, and (3) effect of C. The obtained rate constant of a reaction Cu i + S i = CuS i (g), k CuS R , is 1.37 × 10-9 m4 mol-1 s-1, and the residual rate constant, k CuS r , is 4.11 × 10-10 m4 mol-1 s-1 at 1873 K (1600 °C). Both of them were found to be one order lower than those for Sn evaporation.

  9. Effect of temperature on selenium removal from wastewater by UASB reactors.

    PubMed

    Dessì, Paolo; Jain, Rohan; Singh, Satyendra; Seder-Colomina, Marina; van Hullebusch, Eric D; Rene, Eldon R; Ahammad, Shaikh Ziauddin; Carucci, Alessandra; Lens, Piet N L

    2016-05-01

    The effect of temperature on selenium (Se) removal by upflow anaerobic sludge blanket (UASB) reactors treating selenate and nitrate containing wastewater was investigated by comparing the performance of a thermophilic (55 °C) versus a mesophilic (30 °C) UASB reactor. When only selenate (50 μM) was fed to the UASB reactors (pH 7.3; hydraulic retention time 8 h) with excess electron donor (lactate at 1.38 mM corresponding to an organic loading rate of 0.5 g COD L(-1) d(-1)), the thermophilic UASB reactor achieved a higher total Se removal efficiency (94.4 ± 2.4%) than the mesophilic UASB reactor (82.0 ± 3.8%). When 5000 μM nitrate was further added to the influent, total Se removal was again better under thermophilic (70.1 ± 6.6%) when compared to mesophilic (43.6 ± 8.8%) conditions. The higher total effluent Se concentration in the mesophilic UASB reactor was due to the higher concentrations of biogenic elemental Se nanoparticles (BioSeNPs). The shape of the BioSeNPs observed in both UASB reactors was different: nanospheres and nanorods, respectively, in the mesophilic and thermophilic UASB reactors. Microbial community analysis showed the presence of selenate respirers as well as denitrifying microorganisms. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Reactor-Scale Cultivation of the Hyperthermophilic Methanarchaeon Methanococcus jannaschii to High Cell Densities

    PubMed Central

    Mukhopadhyay, Biswarup; Johnson, Eric F.; Wolfe, Ralph S.

    1999-01-01

    For the hyperthermophilic and barophilic methanarchaeon Methanococcus jannaschii, we have developed a medium and protocols for reactor-scale cultivation that improved the final cell yield per liter from ∼0.5 to ∼7.5 g of packed wet cells (∼1.8 g dry cell mass) under autotrophic growth conditions and to ∼8.5 g of packed wet cells (∼2 g dry cell mass) with yeast extract (2 g liter−1) and tryptone (2 g liter−1) as medium supplements. For growth in a sealed bottle it was necessary to add Se to the medium, and a level of 2 μM for added Se gave the highest final cell yield. In a reactor M. jannaschii grew without added Se in the medium; it is plausible that the cells received Se as a contaminant from the reactor vessel and the H2S supply. But, for the optimal performance of a reactor culture, an addition of Se to a final concentration of 50 to 100 μM was needed. Also, cell growth in a reactor culture was inhibited at much higher Se concentrations. These observations and the data from previous work with methanogen cell extracts (B. C. McBride and R. S. Wolfe, Biochemistry 10:4312–4317, 1971) suggested that from a continuously sparged reactor culture Se was lost in the exhaust gas as volatile selenides, and this loss raised the apparent required level of and tolerance for Se. In spite of having a proteinaceous cell wall, M. jannaschii withstood an impeller tip speed of 235.5 cms−1, which was optimal for achieving high cell density and also was the higher limit for the tolerated shear rate. The organism secreted one or more acidic compounds, which lowered pH in cultures without pH control; this secretion continued even after cessation of growth. PMID:10543823

  11. A comparison of prototype compound parabolic collector-reactors (CPC) on the road to SOLARDETOX technology.

    PubMed

    Funken, K H; Sattler, C; Milow, B; De Oliveira, L; Blanco, J; Fernández, P; Malato, S; Brunott, M; Dischinge, N; Tratzky, S; Musci, M; de Oliveira, J C

    2001-01-01

    Solar photocatalytic detoxification of non-biodegradable chlorinated hydrocarbon solvents (NBCS) is carried out in different concentrating and non concentrating devices using TiO2 as a photocatalyst fixed on the inner surface of the reaction tubes or as a slurry catalyst which has to be removed from the treated water. The reaction is most effective using 200 mg/l of TiO2 as a slurry in a non concentrating CPC reactor. The concentrating parabolic trough reactor has a poor activity because of its minor irradiated reactor surface. Catalyst coated glass tubes are less efficient then the used slurry catalyst. Their advantage is that no catalyst has not to be removed from the treated water and there is no loss of activity during treatment. Yet their physical stability is not sufficient to be competitive to the slurry catalyst. Nevertheless the degradation results are very promising and will possibly lead to commercial applications of this technology.

  12. The Perils of Prototyping.

    ERIC Educational Resources Information Center

    Lowry, Christina; Little, Robert

    1985-01-01

    The benefits of prototyping as a basis for system design include better specifications, earlier discovery of omissions and extensions, and the likelihood of salvaging much of the effort expended on the prototype. Risks and methods of prototyping during rapid systems development are also noted. (Author/MLW)

  13. Reactor Simulator Testing Overview

    NASA Technical Reports Server (NTRS)

    Schoenfeld, Michael P.

    2013-01-01

    Test Objectives Summary: a) Verify operation of the core simulator, the instrumentation & control system, and the ground support gas and vacuum test equipment. b) Examine cooling & heat regeneration performance of the cold trap purification. c) Test the ALIP pump at voltages beyond 120V to see if the targeted mass flow rate of 1.75 kg/s can be obtained in the RxSim. Testing Highlights: a) Gas and vacuum ground support test equipment performed effectively for operations (NaK fill, loop pressurization, and NaK drain). b) Instrumentation & Control system effectively controlled loop temperature and flow rates or pump voltage to targeted settings and ramped within prescribed constraints. It effectively interacted with reactor simulator control model and defaulted back to temperature control mode if the transient fluctuations didn't dampen. c) Cold trap design was able to obtain the targeted cold temperature of 480 K. An outlet temperature of 636 K was obtained which was lower than the predicted 750 K but 156 K higher than the minimum temperature indicating the design provided some heat regeneration. d) ALIP produce a maximum flow rate of 1.53 kg/s at 800 K when operated at 150 V and 53 Hz.

  14. The PreS2 activator MHBs(t) of hepatitis B virus activates c-raf-1/Erk2 signaling in transgenic mice.

    PubMed

    Hildt, Eberhard; Munz, Barbara; Saher, Gesine; Reifenberg, Kurt; Hofschneider, Peter Hans

    2002-02-15

    The large hepatitis B virus (HBV) surface protein (LHBs) and C-terminally truncated middle size surface proteins (MHBs(t)) form the family of the PreS2 activator proteins of HBV. Their transcriptional activator function is based on the cytoplasmic orientation of the PreS2 domain. MHBs(t) activators are paradigmatic for this class of activators. Here we report that MHBs(t) is protein kinase C (PKC)-dependently phosphorylated at Ser28. The integrity of the phosphorylation site is essential for the activator function. MHBs(t) triggers PKC-dependent activation of c-Raf-1/Erk2 signaling that is a prerequisite for MHBs(t)-dependent activation of AP-1 and NF-kappaB. To analyze the pathophysiological relevance of these data in vivo, transgenic mice were established that produce the PreS2 activator MHBs(t) specifically in the liver. In these mice, a permanent PreS2-dependent specific activation of c-Raf-1/Erk2 signaling was observed, resulting in an increased hepatocyte proliferation rate. In transgenics older than 15 months, an increased incidence of liver tumors occurs. These data suggest that PreS2 activators LHBs and MHBs(t) exert a tumor promoter-like function by activation of key enzymes of proliferation control.

  15. Career Line Prototypes.

    ERIC Educational Resources Information Center

    Otto, Luther B.; And Others

    This reference volume on career lines provides two sets of information for 384 different occupations or jobs. Two discussions preface the prototypes: (1) illustration of a career line and elaboration on the concepts and (2) discussion of job and worker characteristics that provide detailed information about each occupational grouping examined. The…

  16. Recent development on the realization of a 1-inch VSiPMT prototype

    NASA Astrophysics Data System (ADS)

    Barbato, F. C. T.; Barbarino, G.; Campajola, L.; Di Capua, F.; Mollo, C. M.; Valentini, A.; Vivolo, D.

    2017-03-01

    The VSiPMT (Vacuum Silicon PhotoMultiplier Tube) is an innovative design for a revolutionary hybrid photodetector. The idea, born with the purpose to use a SiPM for large detection volumes, consists in replacing the classical dynode chain with a SiPM. In this configuration, we match the large sensitive area of a photocathode with the performances of the SiPM technology, which therefore acts like an electron detector and so like a current amplifier. The excellent photon counting capability, fast response, low power consumption and great stability are among the most attractive features of the VSiPMT. In order to realize such a device we first studied the feasibility of this detector both from theoretical and experimental point of view, by implementing a Geant4-based simulation and studying the response of a special non-windowed MPPC by Hamamatsu with an electron beam. Thanks to this result Hamamatsu realized two VSiPMT industrial prototypes with a photocathode of 3mm diameter. We present the progress on the realization of a 1-inch prototype and the preliminary tests we are performing on it.

  17. SiC/SiC Cladding Materials Properties Handbook

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snead, Mary A.; Katoh, Yutai; Koyanagi, Takaaki

    When a new class of material is considered for a nuclear core structure, the in-pile performance is usually assessed based on multi-physics modeling in coordination with experiments. This report aims to provide data for the mechanical and physical properties and environmental resistance of silicon carbide (SiC) fiber–reinforced SiC matrix (SiC/SiC) composites for use in modeling for their application as accidenttolerant fuel cladding for light water reactors (LWRs). The properties are specific for tube geometry, although many properties can be predicted from planar specimen data. This report presents various properties, including mechanical properties, thermal properties, chemical stability under normal and offnormalmore » operation conditions, hermeticity, and irradiation resistance. Table S.1 summarizes those properties mainly for nuclear-grade SiC/SiC composites fabricated via chemical vapor infiltration (CVI). While most of the important properties are available, this work found that data for the in-pile hydrothermal corrosion resistance of SiC materials and for thermal properties of tube materials are lacking for evaluation of SiC-based cladding for LWR applications.« less

  18. Temperature-dependent thermal and thermoelectric properties of n -type and p -type S c1 -xM gxN

    NASA Astrophysics Data System (ADS)

    Saha, Bivas; Perez-Taborda, Jaime Andres; Bahk, Je-Hyeong; Koh, Yee Rui; Shakouri, Ali; Martin-Gonzalez, Marisol; Sands, Timothy D.

    2018-02-01

    Scandium Nitride (ScN) is an emerging rocksalt semiconductor with octahedral coordination and an indirect bandgap. ScN has attracted significant attention in recent years for its potential thermoelectric applications, as a component material in epitaxial metal/semiconductor superlattices, and as a substrate for defect-free GaN growth. Sputter-deposited ScN thin films are highly degenerate n -type semiconductors and exhibit a large thermoelectric power factor of ˜3.5 ×10-3W /m -K2 at 600-800 K. Since practical thermoelectric devices require both n- and p-type materials with high thermoelectric figures-of-merit, development and demonstration of highly efficient p-type ScN is extremely important. Recently, the authors have demonstrated p-type S c1 -xM gxN thin film alloys with low M gxNy mole-fractions within the ScN matrix. In this article, we demonstrate temperature dependent thermal and thermoelectric transport properties, including large thermoelectric power factors in both n- and p-type S c1 -xM gxN thin film alloys at high temperatures (up to 850 K). Employing a combination of temperature-dependent Seebeck coefficient, electrical conductivity, and thermal conductivity measurements, as well as detailed Boltzmann transport-based modeling analyses of the transport properties, we demonstrate that p-type S c1 -xM gxN thin film alloys exhibit a maximum thermoelectric power factor of ˜0.8 ×10-3W /m -K2 at 850 K. The thermoelectric properties are tunable by adjusting the M gxNy mole-fraction inside the ScN matrix, thereby shifting the Fermi energy in the alloy films from inside the conduction band in case of undoped n -type ScN to inside the valence band in highly hole-doped p -type S c1 -xM gxN thin film alloys. The thermal conductivities of both the n- and p-type films were found to be undesirably large for thermoelectric applications. Thus, future work should address strategies to reduce the thermal conductivity of S c1 -xM gxN thin-film alloys, without affecting

  19. LENS: Prototyping Program

    NASA Astrophysics Data System (ADS)

    Rountree, S. Derek

    2013-04-01

    The Low-Energy Neutrino Spectrometer (LENS) prototyping program is broken into two phases. The first of these is μLENS, a small prototype to study the light transmission in the as built LENS scintillation lattice--- a novel detector method of high segmentation in a large liquid scintillation detector. The μLENS prototype is currently deployed and taking data at the Kimballton Underground Research Facility (KURF) near Virginia Tech. I will discuss the Scintillation Lattice construction methods and schemes of the μLENS program for running with minimal channels instrumented to date ˜41 compared to full coverage 216). The second phase of prototyping is the miniLENS detector for which construction is under way. I will discuss the overall design from the miniLENS Scintillation Lattice to the shielding.

  20. Are C1 chondrites chemically fractionated - A trace element study

    NASA Technical Reports Server (NTRS)

    Ebihara, M.; Wolf, R.; Anders, E.

    1982-01-01

    Six C1 chondrite samples and a C2 xenolith from the Plainview H5 chondrite were analyzed by radiochemical neutron activation for a large variety of elements, including rare earths. The sample processing is described, including the irradiation, chemical procedure, rare earths separation, counting techniques, radiochemical purity check, and chemical yields. The results of consistency checks on a number of elements are discussed. Abundances for siderophiles, volatiles, and rare earths are presented and discussed. Tests are presented for fractionation of rare earths and other refractories, compositional uniformity of C1's, and interelement correlations. There is no conclusive evidence for nebular fractionation affecting C1's. Three fractionation-prone rare earths have essentially the same relative abundances in C1's and all other chondrite classes, and hence are apparently not fractionated in C1's.

  1. A prototype analysis of forgiveness.

    PubMed

    Kearns, Jill N; Fincham, Frank D

    2004-07-01

    Many definitions of forgiveness currently exist in the literature. The current research adds to this discussion by utilizing a prototype approach to examine lay conceptions of forgiveness. A prototype approach involves categorizing objects or events in terms of their similarity to a good example, whereas a classical approach requires that there are essential elements that must be present. In Study 1, participants listed the features of forgiveness. Study 2 obtained centrality ratings for these features. In Studies 3 and 4, central features were found to be more salient in memory than peripheral features. Study 5 showed that feature centrality influenced participants' ratings of victims involved in hypothetical transgressions. Thus, the two criteria for demonstrating prototype structure (that participants find it meaningful to judge features in terms of their centrality and that centrality affects cognition) were met.

  2. Load characteristics of a suspended carbon nanotube film heater and the fabrication of a fast-response thermochromic display prototype.

    PubMed

    Liu, Peng; Zhou, Duanliang; Wei, Yang; Jiang, Kaili; Wang, Jiaping; Zhang, Lina; Li, Qunqing; Fan, Shoushan

    2015-04-28

    The influence of heating load on the thermal response of a CNT film heater has been studied. Two kinds of heat dissipation modes, thermal radiation in a vacuum and convection in the atmosphere, are investigated, respectively. It is found that the thermal response slows down with the load quantities in the both cases. We have further studied the thermal response of a CNT film loaded with thermochromic pigment, which is a kind of phase change material. In addition to the thermal response slowing down with the load quantity, it is also found that the phase change of the thermochromic pigments can also slow down the thermal response. With a suspended CNT film heater structure, we have fabricated a thermochromic display prototype, which can switch from room temperature to 50 °C in about 1 s with a brightness contrast of 4.8 under normal indoor illumination. A 16 × 16 pixel thermochromic display prototype can dynamically display Chinese characters driven by a homemade circuit.

  3. Application of X-ray micro-CT for micro-structural characterization of APCVD deposited SiC coatings on graphite conduit.

    PubMed

    Agrawal, A K; Sarkar, P S; Singh, B; Kashyap, Y S; Rao, P T; Sinha, A

    2016-02-01

    SiC coatings are commonly used as oxidation protective materials in high-temperature applications. The operational performance of the coating depends on its microstructure and uniformity. This study explores the feasibility of applying tabletop X-ray micro-CT for the micro-structural characterization of SiC coating. The coating is deposited over the internal surface of pipe structured graphite fuel tube, which is a prototype of potential components of compact high-temperature reactor (CHTR). The coating is deposited using atmospheric pressure chemical vapor deposition (APCVD) and properties such as morphology, porosity, thickness variation are evaluated. Micro-structural differences in the coating caused by substrate distance from precursor inlet in a CVD reactor are also studied. The study finds micro-CT a potential tool for characterization of SiC coating during its future course of engineering. We show that depletion of reactants at larger distances causes development of larger pores in the coating, which affects its morphology, density and thickness. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. A complex of cardiac cytochrome c1 and cytochrome c.

    PubMed

    Chiang, Y L; Kaminsky, L S; King, T E

    1976-01-10

    The interactions of cytochrome c1 and cytochrome c from bovine cardiac mitochondria were investigated. Cytochrome c1 and cytochrome c formed a 1:1 molecular complex in aqueous solutions of low ionic strength. The complex was stable to Sephadex G-75 chromatography. The formation and stability of the complex were independent of the oxidation state of the cytochrome components as far as those reactions studied were concerned. The complex was dissociated in solutions of ionic strength higher than 0.07 or pH exceeding 10 and only partially dissociated in 8 M urea. No complexation occurred when cytochrome c was acetylated on 64% of its lysine residues or photooxidized on its 2 methionine residues. Complexes with molecular ratios of less than 1:1 (i.e. more cytochrome c) were obtained when polymerized cytochrome c, or cytochrome c with all lysine residues guanidinated, or a "1-65 heme peptide" from cyanogen bromide cleavage of cytochrome c was used. These results were interpreted to imply that the complex was predominantly maintained by ionic interactions probably involving some of the lysine residues of cytochrome c but with major stabilization dependent on the native conformations of both cytochromes. The reduced complex was autooxidizable with biphasic kinetics with first order rate constants of 6 X 10(-5) and 5 X U0(-5) s-1 but did not react with carbon monoxide. The complex reacted with cyanide and was reduced by ascorbate at about 32% and 40% respectively, of the rates of reaction with cytochrome c alone. The complex was less photoreducible than cytochrome c1 alone. The complex exhibited remarkably different circular dichroic behavior from that of the summation of cytochrome c1 plus cytochrome c. We concluded that when cytochromes c1 and c interacted they underwent dramatic conformational changes resulting in weakening of their heme crevices. All results available would indicate that in the complex cytochrome c1 was bound at the entrance to the heme crevice of

  5. Placental Expressions of CDKN1C and KCNQ1OT1 in Monozygotic Twins with Selective Intrauterine Growth Restriction.

    PubMed

    Gou, Chenyu; Liu, Xiangzhen; Shi, Xiaomei; Chai, Hanjing; He, Zhi-Ming; Huang, Xuan; Fang, Qun

    2017-10-01

    CDKN1C and KCNQ1OT1 are imprinted genes that might be potential regulators of placental development. This study investigated placental expressions of CDKN1C and KCNQ1OT1 in monozygotic twins with and without selective intrauterine growth restriction (sIUGR). Seventeen sIUGR and fifteen normal monozygotic(MZ) twin pairs were examined. Placental mRNA expressions of CDKN1C and KCNQ1OT1 were detected by real-time fluorescent quantitative PCR. CDKN1C protein expression was detected by immunohistochemical assay and Western-blotting. In the sIUGR group, smaller fetuses had a smaller share of the placenta, and CDKN1C protein expression was significantly increased while KCNQ1OT1 mRNA expression was significantly decreased. The CDKN1C/KCNQ1OT1 mRNA ratio was lower in the larger fetus than in the smaller fetus (p < .05). In the control group, CDKN1C protein expression showed no difference between larger and smaller fetuses, while KCNQ1OT1 mRNA expression was significantly lower in the larger fetus, and the CDKN1C/KCNQ1OT1 mRNA ratio was higher in the larger fetus than in the smaller fetus (p < .05). Our findings showed that pathogenesis of sIUGR may be related to the co-effect of the up-regulated protein expression of CDKN1C and down-regulated mRNA expression of KCNQ1OT1 in the placenta.

  6. Efficient Computational Prototyping of Mixed Technology Microfluidic Components and Systems

    DTIC Science & Technology

    2002-08-01

    AFRL-IF-RS-TR-2002-190 Final Technical Report August 2002 EFFICIENT COMPUTATIONAL PROTOTYPING OF MIXED TECHNOLOGY MICROFLUIDIC...SUBTITLE EFFICIENT COMPUTATIONAL PROTOTYPING OF MIXED TECHNOLOGY MICROFLUIDIC COMPONENTS AND SYSTEMS 6. AUTHOR(S) Narayan R. Aluru, Jacob White...Aided Design (CAD) tools for microfluidic components and systems were developed in this effort. Innovative numerical methods and algorithms for mixed

  7. Determine Operating Reactor to Use for the 2016 PCI Level 1 Milestone

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Clarno, Kevin T.

    2016-01-30

    The Consortium for Advanced Simulation of Light Water Reactors (LWRs) (CASL) Level 1 milestone to “Assess the analysis capability for core-wide [pressurized water reactor] PWR Pellet- Clad Interaction (PCI) screening and demonstrate detailed 3-D analysis on selected sub-region” (L1:CASL.P13.03) requires a particular type of nuclear power plant for the assessment. This report documents the operating reactor and cycles chosen for this assessment in completion of the physics integration (PHI) milestone to “Determine Operating Reactor to use for PCI L1 Milestone” (L3:PHI.CMD.P12.02). Watts Bar Unit 1 experienced (at least) one fuel rod failure in each of cycles 6 and 7, andmore » at least one was deemed to be duty related rather than being primarily related to a manufacturing defect or grid effects. This brief report documents that the data required to model cycles 1–12 of Watts Bar Unit 1 using VERA-CS contains sufficient data to model the PHI portion of the PCI challenge problem. A list of additional data needs is also provided that will be important for verification and validation of the BISON results.« less

  8. Synthesis and crystal structure of (S, S, S, S)-N, N′-bis[N-(P-toluenesulfonamido)-1,2-diphenylethyl]ethylenediamine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, X.-G.; Zhang, T.; Hu, Y.-Y.

    2013-12-15

    (S, S, S, S)-N,N′-bis[N-(p-toluenesulfonamido)-1,2-diphenylethyl] ethylenediamine (C{sub 44}H{sub 46}N{sub 4}O{sub 4}S{sub 2}), has been synthesized and structurally characterized by elemental analysis, {sup 1}H-NMR, MS, IR and single-crystal X-ray diffraction. The title compound contains four chiral centers with C atoms in S configuration. Molecules are connected to one another by hydrogen bonds between sulfonamide nitrogen and sulfonyl oxygen to form chains alone a axis.

  9. Flux effect analysis in WWER-440 reactor pressure vessel steels

    NASA Astrophysics Data System (ADS)

    Kryukov, A.; Blagoeva, D.; Debarberis, L.

    2013-11-01

    The results of long term research programme concerning the determination of irradiation embrittlement dependence on fast neutron flux for WWER-440 reactor pressure vessel steels before and after annealing are presented in this paper. The study of flux effect was carried out on commercial WWER-440 steels which differ significantly in phosphorous (0.013-0.036 wt%) and copper (0.08-0.20 wt%) contents. All specimens were irradiated in surveillance channel positions under similar conditions at high ˜4 × 1012 сm-2 s-1 and low ˜6 × 1011 сm-2 s-1 fluxes (E > 0.5 MeV) at a temperature of 270 °С. The radiation embrittlement was evaluated by transition temperature shift on the basis of Charpy specimens test results. In case of low flux, the measured Tk shifts could be 25-50 °C bigger than the Tk shifts obtained from high flux data. A significant flux effect is observed in WWER-440 reactor pressure vessel steels with higher copper content (>0.13 wt%).

  10. Accelerator based fusion reactor

    NASA Astrophysics Data System (ADS)

    Liu, Keh-Fei; Chao, Alexander Wu

    2017-08-01

    A feasibility study of fusion reactors based on accelerators is carried out. We consider a novel scheme where a beam from the accelerator hits the target plasma on the resonance of the fusion reaction and establish characteristic criteria for a workable reactor. We consider the reactions d+t\\to n+α,d+{{}3}{{H}\\text{e}}\\to p+α , and p+{{}11}B\\to 3α in this study. The critical temperature of the plasma is determined from overcoming the stopping power of the beam with the fusion energy gain. The needed plasma lifetime is determined from the width of the resonance, the beam velocity and the plasma density. We estimate the critical beam flux by balancing the energy of fusion production against the plasma thermo-energy and the loss due to stopping power for the case of an inert plasma. The product of critical flux and plasma lifetime is independent of plasma density and has a weak dependence on temperature. Even though the critical temperatures for these reactions are lower than those for the thermonuclear reactors, the critical flux is in the range of {{10}22}-{{10}24}~\\text{c}{{\\text{m}}-2}~{{\\text{s}}-1} for the plasma density {ρt}={{10}15}~\\text{c}{{\\text{m}}-3} in the case of an inert plasma. Several approaches to control the growth of the two-stream instability are discussed. We have also considered several scenarios for practical implementation which will require further studies. Finally, we consider the case where the injected beam at the resonance energy maintains the plasma temperature and prolongs its lifetime to reach a steady state. The equations for power balance and particle number conservation are given for this case.

  11. 76 FR 7882 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Digital I&C...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Digital I&C Systems The ACRS Subcommittee on Digital Instrumentation & Control (DI&C) Systems will hold a meeting on February 23, 2011, Room T-2B3, 11545 Rockville Pike, Rockville, Maryland. The...

  12. Measurement of the relative prompt production rate of χ c2 and χ c1 in pp collisions at $$\\sqrt{s} = 7\\ \\mathrm{TeV}$$

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chatrchyan, S.; Khachatryan, V.; Sirunyan, A. M.

    A measurement is presented of the relative prompt production rate of chi(c2) and chi(c1) with 4.6 inverse femtobarns of data collected by the CMS experiment at the LHC in pp collisions at sqrt(s) = 7 TeV. The two states are measured via their radiative decays chi(c) to J/psi + gamma, with the photon converting into a dielectron pair for J/psi rapidity abs(y(J/psi)) < 1.0 and photon transverse momentum pt(gamma) > 0.5 GeV. The measurement is given for six intervals of pt(J/psi) between 7 and 25 GeV. The results are compared to theoretical predictions.

  13. IEA-R1 Nuclear Research Reactor: 58 Years of Operating Experience and Utilization for Research, Teaching and Radioisotopes Production

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cardenas, Jose Patricio Nahuel; Filho, Tufic Madi; Saxena, Rajendra

    IEA-R1 research reactor at the Instituto de Pesquisas Energeticas e Nucleares (Nuclear and Energy Research Institute) IPEN, Sao Paulo, Brazil is the largest power research reactor in Brazil, with a maximum power rating of 5 MWth. It is being used for basic and applied research in the nuclear and neutron related sciences, for the production of radioisotopes for medical and industrial applications, and for providing services of neutron activation analysis, real time neutron radiography, and neutron transmutation doping of silicon. IEA-R1 is a swimming pool reactor, with light water as the coolant and moderator, and graphite and beryllium as reflectors.more » The reactor was commissioned on September 16, 1957 and achieved its first criticality. It is currently operating at 4.5 MWth with a 60-hour cycle per week. In the early sixties, IPEN produced {sup 131}I, {sup 32}P, {sup 198}Au, {sup 24}Na, {sup 35}S, {sup 51}Cr and labeled compounds for medical use. During the past several years, a concerted effort has been made in order to upgrade the reactor power to 5 MWth through refurbishment and modernization programs. One of the reasons for this decision was to produce {sup 99}Mo at IPEN. The reactor cycle will be gradually increased to 120 hours per week continuous operation. It is anticipated that these programs will assure the safe and sustainable operation of the IEA-R1 reactor for several more years, to produce important primary radioisotopes {sup 99}Mo, {sup 125}I, {sup 131}I, {sup 153}Sm and {sup 192}Ir. Currently, all aspects of dealing with fuel element fabrication, fuel transportation, isotope processing, and spent fuel storage are handled by IPEN at the site. The reactor modernization program is slated for completion by 2015. This paper describes 58 years of operating experience and utilization of the IEA-R1 research reactor for research, teaching and radioisotopes production. (authors)« less

  14. Ultra-High-Resolution Computed Tomography of the Lung: Image Quality of a Prototype Scanner.

    PubMed

    Kakinuma, Ryutaro; Moriyama, Noriyuki; Muramatsu, Yukio; Gomi, Shiho; Suzuki, Masahiro; Nagasawa, Hirobumi; Kusumoto, Masahiko; Aso, Tomohiko; Muramatsu, Yoshihisa; Tsuchida, Takaaki; Tsuta, Koji; Maeshima, Akiko Miyagi; Tochigi, Naobumi; Watanabe, Shun-Ichi; Sugihara, Naoki; Tsukagoshi, Shinsuke; Saito, Yasuo; Kazama, Masahiro; Ashizawa, Kazuto; Awai, Kazuo; Honda, Osamu; Ishikawa, Hiroyuki; Koizumi, Naoya; Komoto, Daisuke; Moriya, Hiroshi; Oda, Seitaro; Oshiro, Yasuji; Yanagawa, Masahiro; Tomiyama, Noriyuki; Asamura, Hisao

    2015-01-01

    The image noise and image quality of a prototype ultra-high-resolution computed tomography (U-HRCT) scanner was evaluated and compared with those of conventional high-resolution CT (C-HRCT) scanners. This study was approved by the institutional review board. A U-HRCT scanner prototype with 0.25 mm x 4 rows and operating at 120 mAs was used. The C-HRCT images were obtained using a 0.5 mm x 16 or 0.5 mm x 64 detector-row CT scanner operating at 150 mAs. Images from both scanners were reconstructed at 0.1-mm intervals; the slice thickness was 0.25 mm for the U-HRCT scanner and 0.5 mm for the C-HRCT scanners. For both scanners, the display field of view was 80 mm. The image noise of each scanner was evaluated using a phantom. U-HRCT and C-HRCT images of 53 images selected from 37 lung nodules were then observed and graded using a 5-point score by 10 board-certified thoracic radiologists. The images were presented to the observers randomly and in a blinded manner. The image noise for U-HRCT (100.87 ± 0.51 Hounsfield units [HU]) was greater than that for C-HRCT (40.41 ± 0.52 HU; P < .0001). The image quality of U-HRCT was graded as superior to that of C-HRCT (P < .0001) for all of the following parameters that were examined: margins of subsolid and solid nodules, edges of solid components and pulmonary vessels in subsolid nodules, air bronchograms, pleural indentations, margins of pulmonary vessels, edges of bronchi, and interlobar fissures. Despite a larger image noise, the prototype U-HRCT scanner had a significantly better image quality than the C-HRCT scanners.

  15. Ultra-High-Resolution Computed Tomography of the Lung: Image Quality of a Prototype Scanner

    PubMed Central

    Kakinuma, Ryutaro; Moriyama, Noriyuki; Muramatsu, Yukio; Gomi, Shiho; Suzuki, Masahiro; Nagasawa, Hirobumi; Kusumoto, Masahiko; Aso, Tomohiko; Muramatsu, Yoshihisa; Tsuchida, Takaaki; Tsuta, Koji; Maeshima, Akiko Miyagi; Tochigi, Naobumi; Watanabe, Shun-ichi; Sugihara, Naoki; Tsukagoshi, Shinsuke; Saito, Yasuo; Kazama, Masahiro; Ashizawa, Kazuto; Awai, Kazuo; Honda, Osamu; Ishikawa, Hiroyuki; Koizumi, Naoya; Komoto, Daisuke; Moriya, Hiroshi; Oda, Seitaro; Oshiro, Yasuji; Yanagawa, Masahiro; Tomiyama, Noriyuki; Asamura, Hisao

    2015-01-01

    Purpose The image noise and image quality of a prototype ultra-high-resolution computed tomography (U-HRCT) scanner was evaluated and compared with those of conventional high-resolution CT (C-HRCT) scanners. Materials and Methods This study was approved by the institutional review board. A U-HRCT scanner prototype with 0.25 mm x 4 rows and operating at 120 mAs was used. The C-HRCT images were obtained using a 0.5 mm x 16 or 0.5 mm x 64 detector-row CT scanner operating at 150 mAs. Images from both scanners were reconstructed at 0.1-mm intervals; the slice thickness was 0.25 mm for the U-HRCT scanner and 0.5 mm for the C-HRCT scanners. For both scanners, the display field of view was 80 mm. The image noise of each scanner was evaluated using a phantom. U-HRCT and C-HRCT images of 53 images selected from 37 lung nodules were then observed and graded using a 5-point score by 10 board-certified thoracic radiologists. The images were presented to the observers randomly and in a blinded manner. Results The image noise for U-HRCT (100.87 ± 0.51 Hounsfield units [HU]) was greater than that for C-HRCT (40.41 ± 0.52 HU; P < .0001). The image quality of U-HRCT was graded as superior to that of C-HRCT (P < .0001) for all of the following parameters that were examined: margins of subsolid and solid nodules, edges of solid components and pulmonary vessels in subsolid nodules, air bronchograms, pleural indentations, margins of pulmonary vessels, edges of bronchi, and interlobar fissures. Conclusion Despite a larger image noise, the prototype U-HRCT scanner had a significantly better image quality than the C-HRCT scanners. PMID:26352144

  16. Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer.

    PubMed

    Ahmad, Rehan; Alam, Maroof; Hasegawa, Masanori; Uchida, Yasumitsu; Al-Obaid, Omar; Kharbanda, Surender; Kufe, Donald

    2017-02-02

    Colorectal cancer is third most common malignancy and is the second most common cause of cancer-related death. The MUC1 heterodimeric protein is aberrantly overexpressed in colorectal cancer and has been linked to poor outcomes in this disease. Here, we investigate the effects of the MUC1-C subunit inhibitor (GO-203), which disrupts MUC1-C homo-oligomerization, on human colorectal cancer cells. TIGAR mRNA level was determined using qRT-PCR. Western blotting was used to measure TIGAR protein level and AKT-mTOR-S6K1 pathways. Reactive oxygen species and apoptosis were measured by flow cytometry. Effect of MUC1-C peptide, GO-203 was studied on colorectal xenograft tumors. Immunohistochemistry was utilized for TIGAR staining. Treatment of MUC1-overexpressing SKCO-1 and Colo-205 colon cancer cells with GO-203 was associated with downregulation of the TP53-inducible glycolysis and apoptosis regulator (TIGAR) protein. TIGAR promotes the shunting of glycolytic intermediates into the pentose phosphate pathway and thus is of importance for maintaining redox balance. We show that GO-203-induced suppression of TIGAR is mediated by inhibition of AKT and the downstream mTOR pathway. The results also demonstrate that targeting MUC1-C blocks eIF4A cap-dependent translation of TIGAR. In concert with these results, GO-203-induced suppression of TIGAR was associated with decreases in GSH levels. GO-203 treatment also resulted in increases in reactive oxygen species (ROS) and loss of mitochondrial transmembrane potential. Consistent with these results, GO-203 inhibited the growth of colon cancer cells in vitro and as xenografts in nude mice. Inhibition of MUC1-C also downregulated TIGAR expression in xenograft tissues. These findings indicate that MUC1-C is a potential target for the treatment of colorectal cancer. Colorectal cancer patients who overexpress MUC1-C may be candidates for treatment with the MUC1-C inhibitor alone or in combination therapy with other agents.

  17. 10 CFR 72.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.1 Purpose. The... receive, transfer, and possess power reactor spent fuel, power reactor-related Greater than Class C (GTCC... reactor spent fuel, high-level radioactive waste, power reactor-related GTCC waste, and other radioactive...

  18. 10 CFR 72.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.1 Purpose. The... receive, transfer, and possess power reactor spent fuel, power reactor-related Greater than Class C (GTCC... reactor spent fuel, high-level radioactive waste, power reactor-related GTCC waste, and other radioactive...

  19. Cultivation of E. coli in single- and ten-stage tower-loop reactors.

    PubMed

    Adler, I; Schügerl, K

    1983-02-01

    E. Coli was cultivated in batch and continuous operations in the presence of an antifoam agent in stirred-tank and in single- and ten-stage airlift tower reactors with an outer loop. The maximum specific growth rate, mu(m), the substrate yield coefficient, Y(x/s), the respiratory quotient, RQ, substrate conversion, U(s), the volumetric mass transfer coefficient, K(L)a, the specific interfacial area, a, and the specific power input, P/V(L), were measured and compared. If a medium is used with a concentration of complex substrates (extracts) 2.5 times higher than that of glucose, a spectrum of C sources is available and cell regulation influences reactor performance. Both mu(m) and Y(X/S), which were evaluated in batch reactors, cannot be used for continuous reactors or, when measured in stirred-tank reactors, cannot be employed for tower-loop reactors: mu(m) is higher in the stirred-tank batch than in the tower-loop batch reactor, mu(m) and Y(x/s) are higher in the continuous reactor than in the batch single-stage tower-loop reactor. The performance of the single-stage is better than that of the ten-stage reactor due to the inefficient trays employed. A reduction of the medium recirculation rate reduces OTR, U(s), Pr, and Y(X/S) and causes cell sedimentation and flocculation. The volumetric mass transfer coefficient is reduced with increasing cultivation time; the Sauter bubble diameter, d(s), remains constant and does not depend on operational conditions. An increase in the medium recirculation rate reduces k(L)a. The specific power input, P/V(L), for the single-stage tower loop is much lower with the same k(L)a value than for a stirred tank. The relationship k(L)a vs. P/V(L) evaluated for model media in stirred tanks, can also be used for cultivations in these reactors.

  20. 11 CFR 100.2 - Election (2 U.S.C. 431(1)).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... office as independent candidates, or without nomination by a major party (as defined in 26 U.S.C. 9002(6..., as a direct result of which candidates are nominated, in accordance with applicable State law, for... candidate: (i) The day prescribed by applicable State law as the last day to qualify for a position on the...

  1. Thermos reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Labrousse, M.; Lerouge, B.; Dupuy, G.

    1978-04-01

    THERMOS is a water reactor designed to provide hot water up to 120/sup 0/C for district heating or for desalination applications. It is a 100-MW reactor based on proven technology: oxide fuel plate elements, integrated primary circuit, and reactor vessel located in the bottom of a pool. As in swimming pool reactors, the pool is used for biological shielding, emergency core cooling, and fission product filtering (in case of an accident). Before economics, safety is the main characteristic of the concept: no fuel failure admitted, core under water in any accidental configuration, inspection of every ''nuclear'' component, and double-wall containment.

  2. CONTROL RODS FOR NUCLEAR REACTORS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bell, F.R.

    1963-01-16

    A means for controlling the control rod in emergency, when it is desired to shutdown the reactor with the shortest possible delay, is described. When the emergency occurs the control rod is allowed to drop freely under gravity from the control rod support tube into the bore in the reactor core. A normal shutdown is reached almost at the lowest rod position. In the shut-down position and also below it, the control rod had its full effect of reducing the level of activity in the core. When the shut-down position was reached, a brake came into action to decelerate themore » rod and reduce shock and the likelihood of damage. (C.E.S.)« less

  3. A Front-End Electronics Prototype Based on Gigabit Ethernet for the ATLAS Small-Strip Thin Gap Chamber

    NASA Astrophysics Data System (ADS)

    Hu, Kun; Lu, Houbing; Wang, Xu; Li, Feng; Wang, Xinxin; Geng, Tianru; Yang, Hang; Liu, Shengquan; Han, Liang; Jin, Ge

    2017-06-01

    A front-end electronics prototype for the ATLAS small-strip Thin Gap Chamber (sTGC) based on gigabit Ethernet has been developed. The prototype is designed to read out signals of pads, wires, and strips of the sTGC detector. The prototype includes two VMM2 chips developed to read out the signals of the sTGC, a Xilinx Kintex-7 field-programmable gate array (FPGA) used for the VMM2 configuration and the events storage, and a gigabit Ethernet transceiver PHY chip for interfacing with a computer. The VMM2 chip is designed for the readout of the Micromegas detector and sTGC detector, which is composed of 64 linear front-end channels. Each channel integrates a charge-sensitive amplifier, a shaper, several analog-to-digital converters, and other digital functions. For a bunch-crossing interval of 25 ns, events are continuously read out by the FPGA and forwarded to the computer. The interface between the computer and the prototype has been measured to reach an error-free rate of 900 Mb/s, therefore making a very effective use of the available bandwidth. Additionally, the computer can control several prototypes of this kind simultaneously via the Ethernet interface. At present, the prototype will be used for the sTGC performance test. The features of the prototype are described in detail.

  4. Feasibility study of a magnetic fusion production reactor

    NASA Astrophysics Data System (ADS)

    Moir, R. W.

    1986-12-01

    A magnetic fusion reactor can produce 10.8 kg of tritium at a fusion power of only 400 MW —an order of magnitude lower power than that of a fission production reactor. Alternatively, the same fusion reactor can produce 995 kg of plutonium. Either a tokamak or a tandem mirror production plant can be used for this purpose; the cost is estimated at about 1.4 billion (1982 dollars) in either case. (The direct costs are estimated at 1.1 billion.) The production cost is calculated to be 22,000/g for tritium and 260/g for plutonium of quite high purity (1%240Pu). Because of the lack of demonstrated technology, such a plant could not be constructed today without significant risk. However, good progress is being made in fusion technology and, although success in magnetic fusion science and engineering is hard to predict with assurance, it seems possible that the physics basis and much of the needed technology could be demonstrated in facilities now under construction. Most of the remaining technology could be demonstrated in the early 1990s in a fusion test reactor of a few tens of megawatts. If the Magnetic Fusion Energy Program constructs a fusion test reactor of approximately 400 MW of fusion power as a next step in fusion power development, such a facility could be used later as a production reactor in a spinoff application. A construction decision in the late 1980s could result in an operating production reactor in the late 1990s. A magnetic fusion production reactor (MFPR) has four potential advantages over a fission production reactor: (1) no fissile material input is needed; (2) no fissioning exists in the tritium mode and very low fissioning exists in the plutonium mode thus avoiding the meltdown hazard; (3) the cost will probably be lower because of the smaller thermal power required; (4) and no reprocessing plant is needed in the tritium mode. The MFPR also has two disadvantages: (1) it will be more costly to operate because it consumes rather than sells

  5. A novel method of C1-C2 transarticular screw insertion for symptomatic atlantoaxial instability using a customized guiding block: A case report and a technical note.

    PubMed

    Huang, Kuo-Yuan; Lin, Ruey-Mo; Fang, Jing-Jing

    2016-10-01

    Atlantoaxial instability treated with the C1-2 transarticular screw fixation is biomechanically more stable; however, the technique demanding and the potential risk of neurovascular injury create difficulties for clinical usage, and there is still lack of clinical experience till now.We reported an adult female patient with symptomatic atlantoaxial instability due to rheumatoid arthritis that was successfully treated with a bilateral C1-C2 transarticular screw fixation using a customized guiding block. We preoperatively determined the trajectories for bilateral C1-C2 transarticular screws on a 3-dimensional reconstruction model from the computed tomography (CT) and self-developed computer software, and designed a rapid prototyping customized guiding block in order to offer a guide for the entry point and insertion angle of the C1-C2 transarticular screws.The clinical outcome was good, and the follow-up period was >3 years. The accuracy of the screws is good in comparison with preoperative and postoperative CT findings, and no neurovascular injury occurred.The patient was accurately and successfully treated with a bilateral C1-C2 transarticular screw fixation using a customized guiding block.

  6. Assessment of Sensor Technologies for Advanced Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Korsah, Kofi; Ramuhalli, Pradeep; Vlim, R.

    2016-10-01

    Sensors and measurement technologies provide information on processes, support operations and provide indications of component health. They are therefore crucial to plant operations and to commercialization of advanced reactors (AdvRx). This report, developed by a three-laboratory team consisting of Argonne National Laboratory (ANL), Oak Ridge National Laboratory (ORNL) and Pacific Northwest National Laboratory (PNNL), provides an assessment of sensor technologies and a determination of measurement needs for AdvRx. It provides the technical basis for identifying and prioritizing research targets within the instrumentation and control (I&C) Technology Area under the Department of Energy’s (DOE’s) Advanced Reactor Technology (ART) program and contributesmore » to the design and implementation of AdvRx concepts.« less

  7. REACTOR PHYSICS CONSTANTS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1963-07-01

    This second edition is based on data available on March 15, 1961. Sections on constants necessary for the interpretation of experimental data and on digital computer programs for reactor design and reactor physics have been added. 1344 references. (D.C.W.)

  8. CHANDRA OBSERVATIONS OF COMETS C/2012 S1 (ISON) AND C/2011 L4 (PanSTARRS)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snios, Bradford; Kharchenko, Vasili; Lisse, Carey M.

    2016-02-20

    We present our results on the Chandra X-ray Observatory Advanced CCD Imaging Spectrometer (ACIS) observations of the bright Oort Cloud comets C/2012 S1 (ISON) and C/2011 L4 (PanSTARRS). ISON was observed between 2013 October 31–November 06 during variable speed solar wind (SW), and PanSTARRS was observed between 2013 April 17–23 during fast SW. ISON produced an extended parabolic X-ray morphology consistent with a collisionally thick coma, while PanSTARRS demonstrated only a diffuse X-ray-emitting region. We consider these emissions to be from charge exchange (CX) and model each comet's emission spectrum from first principles accordingly. Our model agrees with the observationalmore » spectra and also generates composition ratios for heavy, highly charged SW ions interacting with the cometary atmosphere. We compare our derived SW ion compositions to observational data and find a strong agreement between them. These results further demonstrate the utility of CX emissions as a remote diagnostics tool of both astrophysical plasma interaction and SW composition. In addition, we observe potential soft X-ray emissions via ACIS around 0.2 keV from both comets that are correlated in intensity to the hard X-ray emissions between 0.4–1.0 keV. We fit our CX model to these emissions, but our lack of a unique solution at low energies makes it impossible to conclude if they are cometary CX in origin. Finally, we discuss probable emission mechanism sources for the soft X-rays and explore new opportunities these findings present in understanding cometary emission processes via Chandra.« less

  9. Applications of organocatalytic asymmetric synthesis to drug prototypes--dual action and selective inhibitors of n-nitric oxide synthase with activity against the 5-HT1D/1B subreceptors.

    PubMed

    Hanessian, Stephen; Stoffman, Eli; Mi, Xueling; Renton, Paul

    2011-03-04

    The scope of MacMillan's organocatalytic asymmetric conjugate addition reaction of indoles and electron-rich aromatics to α,β-unsaturated aldehydes has been extended to the use of 3-amino crotonaldehydes as substrates. The aromatics used include indoles as well as an aniline and a furan. The scope and effect of the groups on nitrogen (R, R') has also been studied. The method has been applied to the concise synthesis of an advanced precursor to S-(+)-1, a drug prototype for the treatment of migraine headaches.

  10. Study of the B + c → J/ΨD + s and B + c → J/ΨD* s + decays with the ATLAS detector

    DOE PAGES

    Aad, G.; Abbott, B.; Abdallah, J.; ...

    2016-01-05

    The decays B + c → J/ΨD + s and B + c → J/ΨD* s + are studied with the ATLAS detector at the LHC using a dataset corresponding to integrated luminosities of 4.9 and 20.6 fb –1 of pp collisions collected at centre-of-mass energies √s = 7 TeV and 8 TeV, respectively. Furthermore, signal candidates are identified through J/ψ → μ +μ - and D (*)+ s → Φπ +(γ/π 0) decays.

  11. Photometric follow-up of sungrazing comet C/2012 S1 ISON from OAdM and other observatories

    NASA Astrophysics Data System (ADS)

    Trigo-Rodríguez, J. M.; Moyano-Cambero, C. E.; Meech, K. J.; Rodríguez, D.; Sánchez, A.; Lacruz, J.

    2013-09-01

    Comet C/2012 S1 ISON was discovered on Sept. 21st, 2012 by Russian amateur astronomers Vitaly Nevski and Artyom Novichonok in the framework of a monitoring program called the International Scientific Optical Network (giving the acronym ISON from which the comet has been named). At discovery the comet was at a heliocentric distance of 6.29 A.U. and its magnitude was +18.8, but the computed orbit indicated that the comet was following a nearly parabolic orbit. The current orbit brings C/2012 S1 ISON to an extremely small perihelion distance of about 1 milion km on Nov. 28th, 2013. We have set up a multiband photometric monitoring of this sungrazing comet using 0.8m Telescope Joan Oró of the Montsec Astronomical Observatory (OAdM: www.oadm.cat) and several medium-size amateur telescopes with dedicated experience in cometary photometry [1, 2]. Comet sungrazers are interesting objects as they probably originate from the dynamical evolution of long period comets that typically end their lives colliding with the Sun [3]. They are though to be fragments of primitive ice-rich bodies gravitationally dispersed during the early stages of solar system evolution [4].

  12. Biomechanical Evaluation of a Prototype Foot/Ankle Prosthesis

    PubMed Central

    Quesada, P. M.; Pitkin, M.; Colvin, J.

    2016-01-01

    In this paper, we report on our pilot evaluation of a prototype foot/ankle prosthesis. This prototype has been designed and fabricated with the intention of providing decreased ankle joint stiffness during the middle portion of the stance phase of gait, and increased (i.e., more normal) knee range of motion during stance. Our evaluation involved fitting the existing prototype foot/ankle prosthesis, as well as a traditional solid ankle cushioned heel (SACH) foot, to an otherwise healthy volunteer with a below-knee (BK) amputation. We measured this individual’s lower extremity joint kinematics and kinetics during walking using a video motion analysis system and force platform. These measurements permitted direct comparison of prosthetic ankle joint stiffness and involved side knee joint motion, as well as prosthetic ankle joint moment and power. PMID:10779119

  13. An evaluation of TRAC-PF1/MOD1 computer code performance during posttest simulations of Semiscale MOD-2C feedwater line break transients

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hall, D.G.: Watkins, J.C.

    This report documents an evaluation of the TRAC-PF1/MOD1 reactor safety analysis computer code during computer simulations of feedwater line break transients. The experimental data base for the evaluation included the results of three bottom feedwater line break tests performed in the Semiscale Mod-2C test facility. The tests modeled 14.3% (S-FS-7), 50% (S-FS-11), and 100% (S-FS-6B) breaks. The test facility and the TRAC-PF1/MOD1 model used in the calculations are described. Evaluations of the accuracy of the calculations are presented in the form of comparisons of measured and calculated histories of selected parameters associated with the primary and secondary systems. In additionmore » to evaluating the accuracy of the code calculations, the computational performance of the code during the simulations was assessed. A conclusion was reached that the code is capable of making feedwater line break transient calculations efficiently, but there is room for significant improvements in the simulations that were performed. Recommendations are made for follow-on investigations to determine how to improve future feedwater line break calculations and for code improvements to make the code easier to use.« less

  14. Thermoelectric and structural correlations in (S r1 -x -yC axN dy) Ti O3 perovskites

    NASA Astrophysics Data System (ADS)

    Somaily, H.; Kolesnik, S.; Dabrowski, B.; Chmaissem, O.

    2017-08-01

    Structural and thermoelectric properties are reported for a specially designed class of A -site substituted perovskite titanates, (S r1 -x -yC axN dy) Ti O3 . Two series synthesized with various A -site Sr-rich or Ca-rich (Sr-poor) concentrations were investigated using high-resolution neutron powder diffraction as a function of temperature and Nd doping. Each series was designed to have a nominally constant tolerance factor at room temperature. We determine the room temperature structures as tetragonal I 4 /m c m and orthorhombic P b n m for the Sr-rich and Ca-rich series, respectively. Three low-temperature orthorhombic structures, P b n m , I b m m , and P b c m were also observed for the Sr-rich series, whereas the symmetry of the Ca-rich series remains unchanged throughout the full measured temperature range. Thermoelectric properties of (S r1 -x -yC axN dy) Ti O3 were investigated and correlated with the structural variables. We succeeded in achieving a relatively high figure of merit Z T =0.07 at ˜400 K in the Sr-rich S r0.76C a0.16N d0.08Ti O3 composition which is comparable to that of the best n -type TE SrT i0.80N b0.20O3 oxide material reported to date. For a fixed tolerance factor, the Nd doping enhances the carrier density and effective mass at the expense of the Seebeck coefficient. Thermal conductivity greatly reduces upon Nd doping in the Ca-rich series. With an enhanced Seebeck coefficient at elevated temperatures and reduced thermal conductivity, we predict that S r0.76C a0.16N d0.08Ti O3 and similar compositions have the potential to become some of the best materials in their class of thermoelectric oxides.

  15. Prototype of NASA's Global Precipitation Measurement Mission Ground Validation System

    NASA Technical Reports Server (NTRS)

    Schwaller, M. R.; Morris, K. R.; Petersen, W. A.

    2007-01-01

    NASA is developing a Ground Validation System (GVS) as one of its contributions to the Global Precipitation Mission (GPM). The GPM GVS provides an independent means for evaluation, diagnosis, and ultimately improvement of GPM spaceborne measurements and precipitation products. NASA's GPM GVS consists of three elements: field campaigns/physical validation, direct network validation, and modeling and simulation. The GVS prototype of direct network validation compares Tropical Rainfall Measuring Mission (TRMM) satellite-borne radar data to similar measurements from the U.S. national network of operational weather radars. A prototype field campaign has also been conducted; modeling and simulation prototypes are under consideration.

  16. Evidence for the η(b)(2S) and observation of h(b)(1P)→η(b)(1S)γ and h(b)(2P)→η(b)(1S)γ.

    PubMed

    Mizuk, R; Asner, D M; Bondar, A; Pedlar, T K; Adachi, I; Aihara, H; Arinstein, K; Aulchenko, V; Aushev, T; Aziz, T; Bakich, A M; Bay, A; Belous, K; Bhardwaj, V; Bhuyan, B; Bischofberger, M; Bonvicini, G; Bozek, A; Bračko, M; Brodzicka, J; Browder, T E; Chekelian, V; Chen, A; Chen, P; Cheon, B G; Chilikin, K; Chistov, R; Cho, I-S; Cho, K; Choi, S-K; Choi, Y; Dalseno, J; Danilov, M; Doležal, Z; Drásal, Z; Drutskoy, A; Eidelman, S; Epifanov, D; Fast, J E; Gaur, V; Gabyshev, N; Garmash, A; Golob, B; Haba, J; Hara, T; Hayasaka, K; Hayashii, H; Horii, Y; Hoshi, Y; Hou, W-S; Hsiung, Y B; Hyun, H J; Iijima, T; Ishikawa, A; Itoh, R; Iwabuchi, M; Iwasaki, Y; Iwashita, T; Jaegle, I; Julius, T; Kang, J H; Kapusta, P; Kawasaki, T; Kim, H J; Kim, H O; Kim, J H; Kim, K T; Kim, M J; Kim, Y J; Kinoshita, K; Ko, B R; Koblitz, S; Kodyš, P; Korpar, S; Kouzes, R T; Križan, P; Krokovny, P; Kuhr, T; Kumita, T; Kuzmin, A; Kwon, Y-J; Lange, J S; Lee, S-H; Li, J; Libby, J; Liu, C; Liu, Y; Liu, Z Q; Liventsev, D; Louvot, R; Matvienko, D; McOnie, S; Miyabayashi, K; Miyata, H; Mohanty, G B; Mohapatra, D; Moll, A; Muramatsu, N; Mussa, R; Nakao, M; Natkaniec, Z; Ng, C; Nishida, S; Nishimura, K; Nitoh, O; Nozaki, T; Ohshima, T; Okuno, S; Olsen, S L; Onuki, Y; Pakhlov, P; Pakhlova, G; Park, C W; Park, H; Pestotnik, R; Petrič, M; Piilonen, L E; Poluektov, A; Röhrken, M; Sakai, Y; Sandilya, S; Santel, D; Sanuki, T; Sato, Y; Schneider, O; Schwanda, C; Senyo, K; Seon, O; Sevior, M E; Shapkin, M; Shen, C P; Shibata, T-A; Shiu, J-G; Shwartz, B; Sibidanov, A; Simon, F; Smerkol, P; Sohn, Y-S; Sokolov, A; Solovieva, E; Stanič, S; Starič, M; Sumihama, M; Sumiyoshi, T; Tanida, K; Tatishvili, G; Teramoto, Y; Tikhomirov, I; Trabelsi, K; Tsuboyama, T; Uchida, M; Uehara, S; Uglov, T; Unno, Y; Uno, S; Vanhoefer, P; Varner, G; Varvell, K E; Vinokurova, A; Vorobyev, V; Wang, C H; Wang, M-Z; Wang, P; Wang, X L; Watanabe, M; Watanabe, Y; Williams, K M; Won, E; Yabsley, B D; Yamaoka, J; Yamashita, Y; Yuan, C Z; Zhang, Z P; Zhilich, V

    2012-12-07

    We report the first evidence for the η(b)(2S) using the h(b)(2P)→η(b)(2S)γ transition and the first observation of the h(b)(1P)→η(b)(1S)γ and h(b)(2P)→η(b)(1S)γ transitions. The mass and width of the η(b)(1S) and η(b)(2S) are measured to be m(η(b)(1S))=(9402.4±1.5±1.8) MeV/c(2), m(η(b)(2S))=(9999.0±3.5(-1.9)(+2.8)) MeV/c(2), and Γ(η(b)(1S))=(10.8(-3.7-2.0)(+4.0+4.5)) MeV. We also update the h(b)(1P) and h(b)(2P) mass measurements. We use a 133.4 fb(-1) data sample collected at energies near the Υ(5S) resonance with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider.

  17. MELCOR computer code manuals: Primer and user`s guides, Version 1.8.3 September 1994. Volume 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Summers, R.M.; Cole, R.K. Jr.; Smith, R.C.

    1995-03-01

    MELCOR is a fully integrated, engineering-level computer code that models the progression of severe accidents in light water reactor nuclear power plants. MELCOR is being developed at Sandia National Laboratories for the US Nuclear Regulatory Commission as a second-generation plant risk assessment tool and the successor to the Source Term Code Package. A broad spectrum of severe accident phenomena in both boiling and pressurized water reactors is treated in MELCOR in a unified framework. These include: thermal-hydraulic response in the reactor coolant system, reactor cavity, containment, and confinement buildings; core heatup, degradation, and relocation; core-concrete attack; hydrogen production, transport, andmore » combustion; fission product release and transport; and the impact of engineered safety features on thermal-hydraulic and radionuclide behavior. Current uses of MELCOR include estimation of severe accident source terms and their sensitivities and uncertainties in a variety of applications. This publication of the MELCOR computer code manuals corresponds to MELCOR 1.8.3, released to users in August, 1994. Volume 1 contains a primer that describes MELCOR`s phenomenological scope, organization (by package), and documentation. The remainder of Volume 1 contains the MELCOR Users` Guides, which provide the input instructions and guidelines for each package. Volume 2 contains the MELCOR Reference Manuals, which describe the phenomenological models that have been implemented in each package.« less

  18. Computational and Experimental Investigations of the Coolant Flow in the Cassette Fissile Core of a KLT-40S Reactor

    NASA Astrophysics Data System (ADS)

    Dmitriev, S. M.; Varentsov, A. V.; Dobrov, A. A.; Doronkov, D. V.; Pronin, A. N.; Sorokin, V. D.; Khrobostov, A. E.

    2017-07-01

    Results of experimental investigations of the local hydrodynamic and mass-exchange characteristics of a coolant flowing through the cells in the characteristic zones of a fuel assembly of a KLT-40S reactor plant downstream of a plate-type spacer grid by the method of diffusion of a gas tracer in the coolant flow with measurement of its velocity by a five-channel pneumometric probe are presented. An analysis of the concentration distribution of the tracer in the coolant flow downstream of a plate-type spacer grid in the fuel assembly of the KLT-40S reactor plant and its velocity field made it possible to obtain a detailed pattern of this flow and to determine its main mechanisms and features. Results of measurement of the hydraulic-resistance coefficient of a plate-type spacer grid depending on the Reynolds number are presented. On the basis of the experimental data obtained, recommendations for improvement of the method of calculating the flow rate of a coolant in the cells of the fissile core of a KLT-40S reactor were developed. The results of investigations of the local hydrodynamic and mass-exchange characteristics of the coolant flow in the fuel assembly of the KLT-40S reactor plant were accepted for estimating the thermal and technical reliability of the fissile cores of KLT-40S reactors and were included in the database for verification of computational hydrodynamics programs (CFD codes).

  19. Prototype operational earthquake prediction system

    USGS Publications Warehouse

    Spall, Henry

    1986-01-01

    An objective if the U.S. Earthquake Hazards Reduction Act of 1977 is to introduce into all regions of the country that are subject to large and moderate earthquakes, systems for predicting earthquakes and assessing earthquake risk. In 1985, the USGS developed for the Secretary of the Interior a program for implementation of a prototype operational earthquake prediction system in southern California.

  20. The Effects of Sleep Deprivation on Dissociable Prototype Learning Systems

    PubMed Central

    Maddox, W. Todd; Glass, Brian D.; Zeithamova, Dagmar; Savarie, Zachary R.; Bowen, Christopher; Matthews, Michael D.; Schnyer, David M.

    2011-01-01

    Background: The cognitive neural underpinnings of prototype learning are becoming clear. Evidence points to 2 different neural systems, depending on the learning parameters. A/not-A (AN) prototype learning is mediated by posterior brain regions that are involved in early perceptual learning, whereas A/B (AB) is mediated by frontal and medial temporal lobe regions. Study Objectives: To investigate the effects of sleep deprivation on AN and AB prototype learning and to use established prototype models to provide insights into the cognitive-processing locus of sleep-deprivation deficits. Design: Participants performed an AN and an AB prototype learning task twice, separated by a 24-hour period, with or without sleep between testing sessions. Participants: Eighteen West Point cadets participated in the sleep-deprivation group, and 17 West Point cadets participated in a control group. Measurements and Results: Sleep deprivation led to an AN, but not an AB, performance deficit. Prototype model analyses indicated that the AN deficit was due to changes in attentional focus and a decrease in confidence that is reflected in an increased bias to respond non-A. Conclusions: The findings suggest that AN, but not AB, prototype learning is affected by sleep deprivation. Prototype model analyses support the notion that the effect of sleep deprivation on AN is consistent with lapses in attentional focus that are more detrimental to AN than to AB. This finding adds to a growing body of work that suggests that different performance changes associated with sleep deprivation can be attributed to a common mechanism of changes in simple attention and vigilance. Citation: Maddox WT; Glass BD; Zeithamova D; Savarie ZR; Bowen C; Matthews MD; Schnyer DM. The effects of sleep deprivation on dissociable prototype learning systems. SLEEP 2011;34(3):253-260. PMID:21358842