Sample records for saarse siim veski

  1. Dating Kaali Crater (Estonia) based on charcoal emplaced within proximal ejecta blanket

    NASA Astrophysics Data System (ADS)

    Losiak, Anna; Wild, Eva Maria; Huber, Matthew S.; Wisniowski, Tomasz; Paavel, Kristiina; Jõeleht, Argo; Välja, Rudolf; Plado, Jüri; Kriiska, Aivar; Wilk, Jakob; Zanetti, Michael; Geppert, Wolf D.; Kulkov, Alexander; Steier, Peter; Pirkovic, Irena

    2015-04-01

    The Kaali impact field consists of nine identified craters located on the Saaremaa Island in Estonia. The largest crater is 110 m in diameter (centered around 58°22'21.94"N, 22°40'09.91" E). It was formed by impact of an IAB iron meteoroid into Silurian dolomite target rocks covered by up to a few meters of glacial till (Veski et al. 2007). The age of the Kaali impact structure is still a matter of debate, and the estimates provided by different authors vary considerably between ~6400 BC (Raukas et al. 1995, Moora et al. 2012) and ~400 BC (Rasmussen et al. 2000, Veski et al. 2001). These ages were derived by 14C dating of marker horizons, characterized by a slightly elevated iridium content within the nearby Piila bog yielding a calibrated age of 800-400 BC (Rasmussen et al. 2000, Veski et al. 2001) and occurrences of glassy siliceous material in the Piila bog (~6400 BC: Raukas et al. 1995) or iron microspherules in an organic-rich layer of the Reo gravel pit (6400 BC: Moora et al. 2012). However, the source of the foreign material within those layers was never unequivocally connected with the Kaali crater. 14C dating of material from post-impact organic sediments within Kaali impact craters yielded ages between 1800-1500 BC (Saarse et al. 1991, Veski et al. 2004) and 1450-400 BC (Aaloe et al. 1963). These dates underestimate the age of impact as organic sediments within the crater started to form at unknown period after the impact. On the other hand, Veski et al. (2004) suggested a reservoir effect that might have caused artificially "aging" of the organic matter because the crater was emplaced within Silurian dolomite which is rich in old carbon. The aim of this study is to determine the age of the Kaali crater by 14C dating of organic material covered by the continuous layer of proximal ejecta. This research was conducted in conjunction with a new structural investigation of Kaali Main (Zanetti et al. 2015). Ten samples collected from different locations

  2. Workflow Challenges of Enterprise Imaging: HIMSS-SIIM Collaborative White Paper.

    PubMed

    Towbin, Alexander J; Roth, Christopher J; Bronkalla, Mark; Cram, Dawn

    2016-10-01

    With the advent of digital cameras, there has been an explosion in the number of medical specialties using images to diagnose or document disease and guide interventions. In many specialties, these images are not added to the patient's electronic medical record and are not distributed so that other providers caring for the patient can view them. As hospitals begin to develop enterprise imaging strategies, they have found that there are multiple challenges preventing the implementation of systems to manage image capture, image upload, and image management. This HIMSS-SIIM white paper will describe the key workflow challenges related to enterprise imaging and offer suggestions for potential solutions to these challenges.

  3. A Novel Tool for Microbial Genome Editing Using the Restriction-Modification System.

    PubMed

    Bai, Hua; Deng, Aihua; Liu, Shuwen; Cui, Di; Qiu, Qidi; Wang, Laiyou; Yang, Zhao; Wu, Jie; Shang, Xiuling; Zhang, Yun; Wen, Tingyi

    2018-01-19

    Scarless genetic manipulation of genomes is an essential tool for biological research. The restriction-modification (R-M) system is a defense system in bacteria that protects against invading genomes on the basis of its ability to distinguish foreign DNA from self DNA. Here, we designed an R-M system-mediated genome editing (RMGE) technique for scarless genetic manipulation in different microorganisms. For bacteria with Type IV REase, an RMGE technique using the inducible DNA methyltransferase gene, bceSIIM (RMGE-bceSIIM), as the counter-selection cassette was developed to edit the genome of Escherichia coli. For bacteria without Type IV REase, an RMGE technique based on a restriction endonuclease (RMGE-mcrA) was established in Bacillus subtilis. These techniques were successfully used for gene deletion and replacement with nearly 100% counter-selection efficiencies, which were higher and more stable compared to conventional methods. Furthermore, precise point mutation without limiting sites was achieved in E. coli using RMGE-bceSIIM to introduce a single base mutation of A128C into the rpsL gene. In addition, the RMGE-mcrA technique was applied to delete the CAN1 gene in Saccharomyces cerevisiae DAY414 with 100% counter-selection efficiency. The effectiveness of the RMGE technique in E. coli, B. subtilis, and S. cerevisiae suggests the potential universal usefulness of this technique for microbial genome manipulation.

  4. Hair Zinc Level in Down Syndrome

    ERIC Educational Resources Information Center

    Yenigun, Ayse; Ozkinay, Ferda; Cogulu, Ozgur; Coker, Canan; Cetiner, Nurten; Ozden, Gonca; Aksu, Oguz; Ozkinay, Cihangir

    2004-01-01

    Immunological, endocrinological, and haematological abnormalities are relatively common in people with Down syndrome (Cuadrado & Barrena, 1996; Decoq & Vincker, 1995; Hestnes et al., 1991; Sustrova & Strbak, 1994; Nespoli, Burgio, Ugazio & Maccario, 1993; Kempski, Chessells & Reeves, 1997; Kivivuori, Rajantie, & Siimes, 1996; David et al., 1996;…

  5. New Automated System Available for Reporting Safety Concerns | Poster

    Cancer.gov

    A new system has been developed for reporting safety issues in the workplace. The Environment, Health, and Safety’s (EHS’) Safety Inspection and Issue Management System (SIIMS) is an online resource where any employee can report a problem or issue, said Siobhan Tierney, program manager at EHS.

  6. Quantitative summer and winter temperature reconstructions from pollen and chironomid data in the Baltic-Belarus area

    NASA Astrophysics Data System (ADS)

    Veski, Siim; Seppä, Heikki; Stančikaitė, Migle; Zernitskaya, Valentina; Reitalu, Triin; Gryguc, Gražyna; Heinsalu, Atko; Stivrins, Normunds; Amon, Leeli; Vassiljev, Jüri; Heiri, Oliver

    2015-04-01

    Quantitative reconstructions based on fossil pollen and chironomids are widely used and useful for long-term climate variability estimations. The Lateglacial and early Holocene period (15-8 ka BP) in the Baltic-Belarus (BB) area between 60°-51° N was characterized by sudden shifts in climate due to various climate forcings affecting the climate of the northern hemisphere and North Atlantic, including the proximity of receding ice sheets. Climate variations in BB during the LG were eminent as the southern part of the region was ice free during the Last Glacial Maximum over 19 ka BP, whereas northern Estonia became ice free no sooner than 13 ka BP. New pollen based reconstructions of summer (May-to-August) and winter (December-to-February) temperatures between 15-8 ka BP along a S-N transect in the BB area display trends in temporal and spatial changes in climate variability. These results are completed by two chironomid-based July mean temperature reconstructions (Heiri et al. 2014). The magnitude of change compared with modern temperatures was more prominent in the northern part of BB area than in the southern part. The 4 °C winter and 2 °C summer warming at the start of GI-1 was delayed in the BB area and Lateglacial maximum temperatures were reached at ca 13.6 ka BP, being 4 °C colder than the modern mean. The Younger Dryas cooling in the area was 5 °C colder than present as inferred by all proxies (Veski et al. in press). In addition, our analyses show an early Holocene divergence in winter temperature trends with modern values reaching 1 ka earlier (10 ka BP) in southern BB compared to the northern part of the region (9 ka BP). Heiri, O., Brooks, S.J., Renssen, H., Bedford, A., Hazekamp, M., Ilyashuk, B., Jeffers, E.S., Lang, B., Kirilova, E., Kuiper, S., Millet, L., Samartin, S., Toth, M., Verbruggen, F., Watson, J.E., van Asch, N., Lammertsma, E., Amon, L., Birks, H.H., Birks, J.B., Mortensen, M.F., Hoek, W.Z., Magyari, E., Muñoz Sobrino, C., Seppä, H

  7. American Security and the International Energy Situation. Volume 4. Collected Papers

    DTIC Science & Technology

    1975-04-15

    piograms as jet engine sales Wheat shipments may permit the Soviets to keep chemical industries onenled l.siim.«,, ,1 Pi.l.vs.., I...security and economic interde- pendence among Western advanced industrialized countries. Periodic con- flicts have been replaced by a "security... industrialized countries, creating an "interpenetration of econ- omies." Each development affects the dimensions of the access-to- resources

  8. Enterprise Imaging Governance: HIMSS-SIIM Collaborative White Paper.

    PubMed

    Roth, Christopher J; Lannum, Louis M; Joseph, Carol L

    2016-10-01

    Enterprise imaging governance is an emerging need in health enterprises today. This white paper highlights the decision-making body, framework, and process for optimal enterprise imaging governance inclusive of five areas of focus: program governance, technology governance, information governance, clinical governance, and financial governance. It outlines relevant parallels and differences when forming or optimizing imaging governance as compared with other established broad horizontal governance groups, such as for the electronic health record. It is intended for CMIOs and health informatics leaders looking to grow and govern a program to optimally capture, store, index, distribute, view, exchange, and analyze the images of their enterprise.

  9. A Foundation for Enterprise Imaging: HIMSS-SIIM Collaborative White Paper.

    PubMed

    Roth, Christopher J; Lannum, Louis M; Persons, Kenneth R

    2016-10-01

    Care providers today routinely obtain valuable clinical multimedia with mobile devices, scope cameras, ultrasound, and many other modalities at the point of care. Image capture and storage workflows may be heterogeneous across an enterprise, and as a result, they often are not well incorporated in the electronic health record. Enterprise Imaging refers to a set of strategies, initiatives, and workflows implemented across a healthcare enterprise to consistently and optimally capture, index, manage, store, distribute, view, exchange, and analyze all clinical imaging and multimedia content to enhance the electronic health record. This paper is intended to introduce Enterprise Imaging as an important initiative to clinical and informatics leadership, and outline its key elements of governance, strategy, infrastructure, common multimedia content, acquisition workflows, enterprise image viewers, and image exchange services.

  10. Technical Challenges of Enterprise Imaging: HIMSS-SIIM Collaborative White Paper.

    PubMed

    Clunie, David A; Dennison, Don K; Cram, Dawn; Persons, Kenneth R; Bronkalla, Mark D; Primo, Henri Rik

    2016-10-01

    This white paper explores the technical challenges and solutions for acquiring (capturing) and managing enterprise images, particularly those involving visible light applications. The types of acquisition devices used for various general-purpose photography and specialized applications including dermatology, endoscopy, and anatomic pathology are reviewed. The formats and standards used, and the associated metadata requirements and communication protocols for transfer and workflow are considered. Particular emphasis is placed on the importance of metadata capture in both order- and encounter-based workflow. The benefits of using DICOM to provide a standard means of recording and accessing both metadata and image and video data are considered, as is the role of IHE and FHIR.

  11. Fermentative production of high titer citric acid from corn stover feedstock after dry dilute acid pretreatment and biodetoxification.

    PubMed

    Zhou, Ping-Ping; Meng, Jiao; Bao, Jie

    2017-01-01

    The aim of this work is to study the citric acid fermentation by a robust strain Aspergillus niger SIIM M288 using corn stover feedstock after dry dilute sulfuric acid pretreatment and biodetoxification. Citric acid at 100.04g/L with the yield of 94.11% was obtained, which are comparable to the starch or sucrose based citric acid fermentation. No free wastewater was generated in the overall process from the pretreatment to citric acid fermentation. Abundant divalent metal ions as well as high titer of potassium, phosphate, and nitrogen were found in corn stover hydrolysate. Further addition of extra nutrients showed no impact on increasing citric acid formation except minimum nitrogen source was required. Various fermentation parameters were tested and only minimum regulation was required during the fermentation. This study provided a biorefining process for citric acid fermentation from lignocellulose feedstock with the maximum citric acid titer and yield. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Cyber-Security Issues in Healthcare Information Technology.

    PubMed

    Langer, Steve G

    2017-02-01

    In 1999-2003, SIIM (then SCAR) sponsored the creation of several special topic Primers, one of which was concerned with computer security. About the same time, a multi-society collaboration authored an ACR Guideline with a similar plot; the latter has recently been updated. The motivation for these efforts was the launch of Health Information Portability and Accountability Act (HIPAA). That legislation directed care providers to enable the portability of patient medical records across authorized medical centers, while simultaneously protecting patient confidentiality among unauthorized agents. These policy requirements resulted in the creation of numerous technical solutions which the above documents described. While the mathematical concepts and algorithms in those papers are as valid today as they were then, recent increases in the complexity of computer criminal applications (and defensive countermeasures) and the pervasiveness of Internet connected devices have raised the bar. This work examines how a medical center can adapt to these evolving threats.

  13. The role of fire in the Central European lowlands during the Holocene: what we know so far

    NASA Astrophysics Data System (ADS)

    Dietze, Elisabeth; Theuerkauf, Martin; Słowiński, Michał; Brauer, Achim

    2017-04-01

    The modern landscape of the Central European lowlands results from the complex interaction between its geological and geomorphological configuration that developed during and after the last glaciation as well as its Holocene vegetation history, climate evolution and human activity. Although also fire is known to play a fundamental role in many ecosystems of the world and to be one of the major tools for anthropogenic land cover change, Holocene paleofire history has only marginally been studied in the area of the Central European lowlands so far. Here, we will present the first attempt to establish a Holocene fire synthesis for the Central European lowlands. In a first step, we aim to reconstruct the regional Holocene fire history by comparing available sedimentary charcoal records from lakes and peatlands of northern Germany, northern Poland and the Baltic countries. We will present the current knowledge on the role of fire during different time windows such as the Neolithic period, the Medieval time and the onset of industrialization. In addition, we will discuss the interaction between fire, human activity, vegetation and climate change during the last 250 years in more detail using high-resolution records of sedimentary charcoal and the fire biomarkers levoglucosan, mannosan and galactosan from the annually laminated lake sediments of Lake Czechowskie, northern Poland. Teams: CEL synthesis - A. Feurdean, M. Obremska, M. Lamentowicz, K. Marcisz, W. Dörfler, I. Feeser, N. Dräger, F. Ott, T. Giesecke, S. Jahns, L. Shumilovskikh, S. Veski, M. Wieckowska-Lüth, J. Wiethold; Czechowskie fire biomarkers - E.C. Hopmans, L.T. Schreuder, M. Obremska, A. Pieńczewska, O. Blarquez, F. Ott, D. Brykala, S. Schouten

  14. The Current State and Path Forward For Enterprise Image Viewing: HIMSS-SIIM Collaborative White Paper.

    PubMed

    Roth, Christopher J; Lannum, Louis M; Dennison, Donald K; Towbin, Alexander J

    2016-10-01

    Clinical specialties have widely varied needs for diagnostic image interpretation, and clinical image and video image consumption. Enterprise viewers are being deployed as part of electronic health record implementations to present the broad spectrum of clinical imaging and multimedia content created in routine medical practice today. This white paper will describe the enterprise viewer use cases, drivers of recent growth, technical considerations, functionality differences between enterprise and specialty viewers, and likely future states. This white paper is aimed at CMIOs and CIOs interested in optimizing the image-enablement of their electronic health record or those who may be struggling with the many clinical image viewers their enterprises may employ today.

  15. Prototypes for Content-Based Image Retrieval in Clinical Practice

    PubMed Central

    Depeursinge, Adrien; Fischer, Benedikt; Müller, Henning; Deserno, Thomas M

    2011-01-01

    Content-based image retrieval (CBIR) has been proposed as key technology for computer-aided diagnostics (CAD). This paper reviews the state of the art and future challenges in CBIR for CAD applied to clinical practice. We define applicability to clinical practice by having recently demonstrated the CBIR system on one of the CAD demonstration workshops held at international conferences, such as SPIE Medical Imaging, CARS, SIIM, RSNA, and IEEE ISBI. From 2009 to 2011, the programs of CADdemo@CARS and the CAD Demonstration Workshop at SPIE Medical Imaging were sought for the key word “retrieval” in the title. The systems identified were analyzed and compared according to the hierarchy of gaps for CBIR systems. In total, 70 software demonstrations were analyzed. 5 systems were identified meeting the criterions. The fields of application are (i) bone age assessment, (ii) bone fractures, (iii) interstitial lung diseases, and (iv) mammography. Bridging the particular gaps of semantics, feature extraction, feature structure, and evaluation have been addressed most frequently. In specific application domains, CBIR technology is available for clinical practice. While system development has mainly focused on bridging content and feature gaps, performance and usability have become increasingly important. The evaluation must be based on a larger set of reference data, and workflow integration must be achieved before CBIR-CAD is really established in clinical practice. PMID:21892374

  16. Pleistocene lake level changes in Western Mongolia

    NASA Astrophysics Data System (ADS)

    Borodavko, P. S.

    2009-04-01

    .Petersburg, Nauka, 304 p. 4. Tarasov, P.E., Harrison, S.P., Saarse, L., Pushenko, M.Ya., Andreev, A.A., Aleshinskaya, Z.V., Davydova, N.N., Dorofeyuk, N.I., Efremov, Yu.V., Khomutova, V.I., Sevastyanov, D.V., Tamosaitis, J., Dorofeyuk, N.I., Efremov, Yu.V., Khomutova, V.I., Sevastyanov, D.V., Tamosaitis, J.,Uspenskaya, O.N., Yakushko, O.F. and Tarasova, I.V., 1994. Lake status records from the Former Soviet Union and Mongolia: Data Base Documentation, World Data Center -A for Paleoclimatology NOAA Paleoclimatology Program, Paleoclimatology Publications Series Report No 2, Boulder, Colorado USA, 274 p. 5. Tserensodnom, Zh., 1971. Mongol orny Nuur. Ulaanbaatar, TUAH, 202 p. 6. Vipper, P., Dorofeyuk, N., Liiva, A., Meteltseva, E., and Sokolovskaya, V., 1981. Palaeogeography of the Central Mongolia during the upper Pleistocene and Holocene. Izv. Akad. Nauk ESSR, Ser. Biol., vol. 30, no. 1, pp. 74-82.