Sample records for safeguards acrs public
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-10
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on May 23, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to public...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-18
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on EPR The ACRS Subcommittee on EPR will hold a meeting on May 21, 2010, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to public attendance. The agenda for...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-16
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on May 22, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to public...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-29
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on June 20, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to public...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-17
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on AP-1000; Notice of Meeting The ACRS Subcommittee on AP-1000 will hold a meeting on January 18, 2013, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to public...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-12
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on US-APWR; Notice of Meeting The ACRS Subcommittee on US-APWR will hold a meeting on September 20, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to public...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-25
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Future Plant Designs; Notice of Meeting The ACRS Subcommittee on Future Plant Designs will hold a meeting on April 9, 2013, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to public attendance....
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-17
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Future Plant Designs; Notice of Meeting The ACRS Subcommittee on Future Plant Designs will hold a meeting on November 2, 2011, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to public...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-17
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Future Plant Designs; Notice of Meeting The ACRS Subcommittee on Future Plant Designs will hold a meeting on January 17, 2013, Room T-2B3, 11545 Rockville Pike, Rockville, Maryland. The meeting will be open to public attendance, wit...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-27
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Reliability & PRA; Notice of Meeting The ACRS Subcommittee on Reliability & PRA will hold a..., 2013. Cayetano Santos, Chief, Technical Support Branch, Advisory Committee on Reactor Safeguards. [FR...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-08
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Advanced Boiling Water Reactor The ACRS Subcommittee on Advanced Boiling Water Reactor (ABWR... Committee on Reactor Safeguards. [FR Doc. 2013-08131 Filed 4-5-13; 8:45 am] BILLING CODE 7590-01-P ...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-08
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Reliability and Probabilistic Risk Assessment The ACRS Subcommittee on Reliability and PRA will hold a meeting [[Page 55718
-
75 FR 55365 - Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Joint Subcommittee
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-10
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Joint Subcommittee The ACRS Subcommittees on Thermal Hydraulics Phenomena; Advanced Boiling Water Reactor (ABWR); and Materials, Metallurgy, and Reactor Fuels will hold a joint meeting on October 4, 2010...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-14
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS), Meeting of the ACRS Subcommittee on Fukushima; Cancellation of the January 18, 2013, ACRS Subcommittee Meeting The ACRS Subcommittee meeting on Fukushima scheduled for January 18, 2013 has been cancelled. The notice of this meeting...
-
10 CFR 52.87 - Referral to the Advisory Committee on Reactor Safeguards (ACRS).
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 2 2011-01-01 2011-01-01 false Referral to the Advisory Committee on Reactor Safeguards (ACRS). 52.87 Section 52.87 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS... Reactor Safeguards (ACRS). The Commission shall refer a copy of the application to the ACRS. The ACRS...
-
10 CFR 52.87 - Referral to the Advisory Committee on Reactor Safeguards (ACRS).
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 2 2010-01-01 2010-01-01 false Referral to the Advisory Committee on Reactor Safeguards (ACRS). 52.87 Section 52.87 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS... Reactor Safeguards (ACRS). The Commission shall refer a copy of the application to the ACRS. The ACRS...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-24
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels The ACRS Subcommittee on Materials, Metallurgy & Reactor... would result in a major inconvenience. Dated: September 17, 2010. Antonio Dias, Chief, Reactor Safety...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-08
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels The ACRS Subcommittee on Materials, Metallurgy & Reactor...'' for reactor coolant system (RCS) components, as mentioned in 10 CFR 50 Appendix A, GDC-4. The...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-28
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Advanced Boiling Water Reactor (ABWR); Notice of Meeting The ACRS Subcommittee on Advanced Boiling Water Reactor (ABWR) will hold a meeting on February 8, 2011, 11545 Rockville Pike, Rockville, MD...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-02
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Reliability and Probabilistic Risk Assessment (PRA); Notice of Meeting The ACRS Subcommittee on Reliability and Probabilistic Risk Assessment (PRA), Room T-2B1, 11545 Rockville Pike, Rockville, Maryland...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-24
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Plant License Renewal The ACRS Subcommittee on Plant License Renewal will hold a meeting on..., ``Generic Aging Lessons Learned (GALL) Report.'' The Subcommittee will hear presentations by and hold...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-29
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on September 5, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. [[Page 52372
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-01
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee On Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on August... Fukushima Near Term Task Force (NTTF) Recommendation 1: Enhanced Regulatory Framework. The Subcommittee will...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-30
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Thermal Hydraulics Phenomena; Notice of Meeting The ACRS Subcommittee on Thermal Hydraulics... Revision 4 to Regulatory Guide 1.82, ``Water Sources for Long-Term Recirculation Cooling Following a Loss...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-28
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on June 4, 2013, Room T-2B1, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-14
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS), Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on June 23, 2011, Room T-2B3, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-16
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS), Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on February 6, 2013, Room T-2B1, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-23
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on December 15, 2011, Room T-2B1, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-26
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Advanced Boiling Water Reactor; Notice of Meeting The ACRS Subcommittee on Advanced Boiling Water Reactor (ABWR) will hold a meeting on January 16, 2013, Room T-2B3, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-17
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on May 22, 2013, Room T-2B1, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-07
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Economic Simplified Boiling Water Reactor; Notice of Meeting The ACRS Subcommittee on Economic Simplified Boiling Water Reactor (ESBWR) will hold a meeting on November 30, 2011, Room T-2B1, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-10
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards (ACRS); Meeting of the Acrs Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on June 17, 2013, Room T-2B1, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-15
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on December 4, 2012, Room T-2B3, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-24
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on June 5, 2012, Room T-2B1, 11545 Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-12
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on September 18, 2012, Room T-2B3, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-27
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on August 17, 2011, Room T-2B3, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-26
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on December 3, 2013, Room T-2B1, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-25
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on April 9, 2013, Room T-2B3, 11545 Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-26
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on July 10, 2012, Room T-2B1, 11545 Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-07
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommitte on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on November 19, 2013, Room T-2B1, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-08
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on September 23, 2011, Room T-2B3, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-18
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on May 18, 2010, Room T-2B1, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-18
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on May 18, 2010, Room T-2B1, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-10
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on May 25, 2011, Room T-2B3, 11545 Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-14
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards (ACRS), Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on June 23, 2011, Room T-2B1, 11545 Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-24
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on October 22, 2010, Room T-2B1, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-02
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on April 21, 2010, Room T2-B3, at 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-08
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of The ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on September 22, 2011, Room T-2B1, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-29
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on January 11, 2011, Room T-2B3, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-29
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on February 17, 2010, Room T2-B1, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-29
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on January 12, 2011, Room T-2B3, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-27
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on January 16, 2014, Room T-2B1, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-03
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on October 4, 2011, Room T-2B1, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-20
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Thermal Hydraulics Phenomena The ACRS Subcommittee on Thermal Hydraulics Phenomena will hold a meeting on September 7, 2010, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-21
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Thermal Hydraulic Phenomena The ACRS Subcommittee on Thermal Hydraulic Phenomena will hold a meeting on October 18, 2010, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-25
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS), Meeting of the ACRS Subcommittee on Reliability and Probabilistic Risk Assessment; Notice of Meeting The ACRS Subcommittee on Reliability and Probabilistic Risk Assessment (PRA) will hold a meeting on May 11, 2011, Room T-2B3, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-18
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS), Meeting of the ACRS Subcommittee on Reliability and Probabilistic Risk Assessment; Notice of Meeting The ACRS Subcommittee on Reliability and Probabilistic Risk Assessment (PRA) will hold a meeting on December 14, 2011, Room T-2B3...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-17
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on January 16, 2013, Room T-2B3, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-13
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on September 19, 2013, Room T-2B3, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-27
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on January 14, 2014, Room T-2B1, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-26
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on December 4, 2013, Room T-2B1, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-02
... Nuclear Regulatory Commission Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on May 10, 2011, Room T-2B1, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-10
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on May 26....m. The Subcommittee will review recent events at the Fukushima site in Japan. The Subcommittee will...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-09
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittees on Reliability and PRA and Fukushima; Revision to Notice of Meetings The (ACRS) Subcommittee on Fukushima originally scheduled for the afternoon of August 14, 2012, has been moved to the morning of August...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-14
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on June 23....m. The Subcommittee will review recent events at the Fukushima site in Japan. The Subcommittee will...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-23
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Digital Instrumentation and Control Systems; Notice of Meeting The ACRS Subcommittee on Digital Instrumentation and Control Systems (DI&C) will hold a meeting on September 7, 2011, Room T-2B1, 11545 Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-28
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS), Meeting of the ACRS Subcommittee on Advanced Boiling Water Reactor; Notice of Meeting The ACRS Subcommittee on Advanced Boiling Water Reactor (ABWR) will hold a meeting on October 2, 2012, Room T-2B1, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-22
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of The ACRS Subcommittee on Materials, Metallurgy And Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy and Reactor Fuels will hold a meeting on April 6, 2011, Room T-2B3, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-13
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS), Meeting of the ACRS Subcommittee on Advanced Boiling Water Reactor; Notice of Meeting The ACRS Subcommittee on Advanced Boiling Water Reactor (ABWR) will hold a meeting on June 21, 2011, Room T-2B1, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-11
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Economic Simplified Boiling Water Reactor; Notice of Meeting The ACRS Subcommittee on Economic Simplified Boiling Water Reactor (ESBWR) will hold a meeting on October 21, 2011, Room T-2B1, 11545 Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-10
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Economic Simplified Boiling Water Reactor; Notice of Meeting The ACRS Subcommittee on Economic Simplified Boiling Water Reactor (ESBWR) will hold a meeting on May 26, 2011, Room T-2B1, 11545 Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-21
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Radiation Protection and Nuclear Materials Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on June 20, 2011, Room T-2B1, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-25
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS), Meeting of the ACRS Subcommittee on Thermal Hydraulic Phenomena; Notice of Meeting The ACRS Subcommittee on Thermal Hydraulic Phenomena will hold a meeting on May 8-9, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-04
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Reliability and Probabilistic Risk Assessment (PRA); Notice of Meeting The ACRS Subcommittee on Reliability and Probabilistic Risk Assessment (PRA) will hold a meeting on April 20, 2011, Room T-2B1, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-03
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Digital Instrumentation and Control Systems; Notice of Meeting The ACRS Subcommittee on Digital Instrumentation and Control Systems (DI&C) will hold a meeting on October 30, 2012, Room T-2B1, 11545 Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-01
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on August 14, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-15
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on December... flooding reevaluations requested in the March 2012 10 CFR 50.54(f) letters to address Fukushima Near-Term...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-30
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee On Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on November 5, 2013, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-25
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on August... task force review of the events at the Fukushima Dai-Ichi reactor site in Japan. The Subcommittee will...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-15
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on December 4, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-17
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on January 18, 2013, Room T-2B3, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-19
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on September 4, 2013, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-21
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on September 18, 2013, Room T-2B3, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-28
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on October 3, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-18
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on October 31, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to...
-
10 CFR 52.141 - Referral to the Advisory Committee on Reactor Safeguards (ACRS).
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 2 2010-01-01 2010-01-01 false Referral to the Advisory Committee on Reactor Safeguards (ACRS). 52.141 Section 52.141 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS... Committee on Reactor Safeguards (ACRS). The Commission shall refer a copy of the application to the ACRS...
-
10 CFR 52.53 - Referral to the Advisory Committee on Reactor Safeguards (ACRS).
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 2 2011-01-01 2011-01-01 false Referral to the Advisory Committee on Reactor Safeguards (ACRS). 52.53 Section 52.53 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS... Committee on Reactor Safeguards (ACRS). The Commission shall refer a copy of the application to the ACRS...
-
10 CFR 52.165 - Referral to the Advisory Committee on Reactor Safeguards (ACRS).
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 2 2010-01-01 2010-01-01 false Referral to the Advisory Committee on Reactor Safeguards (ACRS). 52.165 Section 52.165 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS... Committee on Reactor Safeguards (ACRS). The Commission shall refer a copy of the application to the ACRS...
-
10 CFR 52.165 - Referral to the Advisory Committee on Reactor Safeguards (ACRS).
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 2 2011-01-01 2011-01-01 false Referral to the Advisory Committee on Reactor Safeguards (ACRS). 52.165 Section 52.165 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS... Committee on Reactor Safeguards (ACRS). The Commission shall refer a copy of the application to the ACRS...
-
10 CFR 52.141 - Referral to the Advisory Committee on Reactor Safeguards (ACRS).
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 2 2011-01-01 2011-01-01 false Referral to the Advisory Committee on Reactor Safeguards (ACRS). 52.141 Section 52.141 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS... Committee on Reactor Safeguards (ACRS). The Commission shall refer a copy of the application to the ACRS...
-
10 CFR 52.53 - Referral to the Advisory Committee on Reactor Safeguards (ACRS).
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 2 2010-01-01 2010-01-01 false Referral to the Advisory Committee on Reactor Safeguards (ACRS). 52.53 Section 52.53 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS... Committee on Reactor Safeguards (ACRS). The Commission shall refer a copy of the application to the ACRS...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-03
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Digital Instrumentation and Control Systems; Notice of Meeting The ACRS Subcommittee on Digital Instrumentation and Control Systems (DI&C) will hold a meeting on June 7, 2011, Room T-2B1, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-29
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Evolutionary Power Reactor (EPR); Notice of Meeting The ACRS Subcommittee on EPR will hold a..., November 30, 2010--8:30 a.m. Until 2 p.m. The Subcommittee will review Selected Chapters of the US EPR...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-30
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Evolutionary Power Reactor; Notice of Meeting The ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR) will hold a meeting on November 6, 2013, Room T-2B1, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-15
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on May 22- 23, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open to...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-25
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Fukushima; Notice of Meeting The ACRS Subcommittee on Fukushima will hold a meeting on April 10... reevaluations requested in the March 2012 10 CFR 50.54(f) letters to address Fukushima Near-Term Task Force...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-07
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Advanced Boiling Water Reactor; Notice of Meeting The ACRS Subcommittee on Advanced Boiling Water Reactor (ABWR) will hold a meeting on November 22, 2013, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The meeting will be...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-21
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Advanced Boiling Water Reactor; Notice of Meeting The ACRS Subcommittee on Advanced Boiling Water Reactor (ABWR) will hold a meeting on July 9, 2013, Room T-2B3, 11545 Rockville Pike, Rockville, Maryland. The meeting will be open to...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-03
... Expanded Operating Domains-Power Distribution Validation and Pin-by-Pin Gamma Scan). The Subcommittee will... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting on the ACRS Subcommittee on Power Uprates Notice of Meeting The ACRS Subcommittee on Power Uprates will hold a meeting on...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-24
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee On Future Plant Designs The ACRS Subcommittee on Future Plant Designs will hold a meeting on..., 2010, 1 p.m. Until 5 p.m. The Subcommittee will review current Design Acceptance Criteria associated...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-03
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Planning and Procedures The ACRS Subcommittee on Planning and Procedures will hold a meeting on... adjusted by the Chairman as necessary to facilitate the conduct of the meeting, persons planning to attend...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-20
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Planning and Procedures The ACRS Subcommittee on Planning and Procedures will hold a meeting on... facilitate the conduct of the meeting, persons planning to attend should check with these references if such...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-23
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR); Notice of Meeting The ACRS Subcommittee on U.S. EPR... of the Safety Evaluation Report (SER) with open items associated with U.S. EPR Design Control...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-10
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on US-APWR; Notice of Meeting The ACRS Subcommittee on US-APWR will hold a meeting on January 15....'' Both Topical Reports are associated with the design certification of the US-APWR. The Subcommittee will...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-06
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on US-APWR; Notice of Meeting The ACRS Subcommittee on US-APWR will hold a meeting on September 17...) associated with the US-APWR design certification and the Comanche Peak Combined License Application (COLA...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-25
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on US-APWR; Notice of Meeting The ACRS Subcommittee on US-APWR will hold a meeting on October 1... cooling for the US-APWR design. The Subcommittee will hear presentations by and hold discussions with...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-05
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on US-APWR; Notice of Meeting The ACRS Subcommittee on US-APWR will hold a meeting on February 21... the Safety Evaluation Reports (SERs) associated with the US-APWR design certification and the Comanche...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-11
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee On US-APWR; Notice of Meeting The ACRS Subcommittee on US-APWR will hold a meeting on October 18... Subcommittee will review Chapter 4, ``Reactor,'' of the Safety Evaluation Reports associated with the US-APWR...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-19
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Advanced Pressurized Power Reactor; Notice of Meeting The ACRS Subcommittee on U.S. Advanced Pressurized Power Reactor (US-APWR) will hold a meeting on July 9-10, 2012, Room T-2B3, 11545...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-27
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Evolutionary Power Reactor; Notice of Meeting The ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR) will hold a meeting on August 18, 2011, Room T-2B3, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-26
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR); Notice of Meeting The ACRS Subcommittee on U.S. EPR... 6 and Chapter 15 of the U.S. EPR Safety Evaluation Report (SER) with Open Items. The Subcommittee...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-19
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on AP1000; Notice of Meeting The ACRS Subcommittee on the AP1000 will hold a meeting on April 22... Loss of Large Areas due to Fire/Explosions, and by Westinghouse on the subject of Shield Building...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-28
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Future Plant Designs The ACRS Subcommittee on Future Plant Designs will hold a meeting on February 9, 2011, at 11545 Rockville Pike, Room T-2B1, Rockville, Maryland. The entire meeting will be open...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-22
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Future Plant Designs The ACRS Subcommittee on Future Plant Designs will hold a meeting on April 5, 2011, at 11545 Rockville Pike, Room T-2B1, Rockville, Maryland. The entire meeting will be open...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-15
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on US-APWR; Notice of Meeting The ACRS Subcommittee on US-APWR will hold a meeting on November 20... Sections 3.7 and 3.8) of the Safety Evaluation Report (SER) associated with the US-APWR design...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-08
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on US-APWR The ACRS Subcommittee on US-APWR will hold a meeting on April 25- 26, 2013, Room T-2B1... 7, ``Instrumentation and Control,'' of the Safety Evaluation Report (SER) associated with the US...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-12
...: Draft Regulatory Guide DG-1237, ``Guidance on Making Changes to Emergency Plans for Nuclear Power Reactors,'' Interim Staff Guidance (ISG) NSIR/DPR-ISG-01, ``Emergency Planning for Nuclear Power Plants... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-23
... review Draft Final Regulatory Guide (RG) 1.93, ``Availability of Electric Power Sources,'' Revision 1 and new Draft Final RG 1.218, ``Condition Monitoring Techniques for Electric Cables Used in Nuclear Power... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-29
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR); Notice of Meeting The ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR) will hold a meeting on January 12, 2011, Room T-2B1, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-11
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Digital I&C Systems The ACRS Subcommittee on Digital Instrumentation & Control (DI&C) Systems will hold a meeting on February 23, 2011, Room T-2B3, 11545 Rockville Pike, Rockville, Maryland. The...
-
10 CFR 52.23 - Referral to the Advisory Committee on Reactor Safeguards (ACRS).
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 2 2011-01-01 2011-01-01 false Referral to the Advisory Committee on Reactor Safeguards (ACRS). 52.23 Section 52.23 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS... on Reactor Safeguards (ACRS). The Commission shall refer a copy of the application for an early site...
-
10 CFR 52.23 - Referral to the Advisory Committee on Reactor Safeguards (ACRS).
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 2 2010-01-01 2010-01-01 false Referral to the Advisory Committee on Reactor Safeguards (ACRS). 52.23 Section 52.23 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS... on Reactor Safeguards (ACRS). The Commission shall refer a copy of the application for an early site...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-20
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Digital I&C Systems The ACRS Subcommittee on Digital Instrumentation and Controls (I&C) Systems...: Wednesday, September 8, 2010--8:30 a.m. until 12 p.m. The Subcommittee will review Digital I&C Interim Staff...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-13
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Digital I&C; Notice of Meeting The ACRS Subcommittee on Digital I&C will hold a meeting on November 16, 2012, Room T-2B1, 11545 Rockville Pike, Rockville, Maryland. The entire meeting will be open...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-22
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards; Meeting of the ACRS Subcommittee on Digital Instrumentation & Control (DI&C); Revision to February 23, 2011, ACRS Meeting Federal Register Notice The Federal Register Notice for the ACRS Subcommittee Meeting on Digital Instrumentation...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-17
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards Meeting of the ACRS Subcommittee on Thermal-Hydraulics Phenomena; Revision to February 22, 2012, ACRS Meeting Federal Register Notice The Federal Register Notice for the ACRS Subcommittee meeting on Thermal-Hydraulics Phenomena...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-17
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards Meeting of the ACRS Subcommittee on Power Uprates; Revision to February 23, 2012, ACRS Meeting Federal Register Notice The Federal Register Notice for the ACRS Subcommittee meeting on Power Uprates, scheduled to be held on February 23...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-15
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards; Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels Revision to September 21, 2011, ACRS Meeting; Federal... Reactor Fuels is being revised to correct the meeting date to Wednesday, September 21, 2011. The notice of...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-07
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards Meeting of The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels Revision to December 15, 2011, ACRS Meeting Federal... & Reactor Fuels scheduled to be held on December 15, 2011, is being revised to notify the following: The...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-09
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards Meeting of the ACRS Subcommittee on EPR; Cancellation to May 11, 2011, ACRS Meeting-- Federal Register Notice The Federal Register Notice for the ACRS Subcommittee Meeting on the design certification application review of the U.S...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-09
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the Subcommittee on Advanced Boiling Water Reactor (ABWR); Notice of Meeting The ACRS Subcommittee on ABWR will... would result in major inconvenience. Dated: March 3, 2010. Antonio F. Dias, Chief, Reactor Safety Branch...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-04
... Westinghouse Electric Company, General Electric--Hitachi Nuclear Energy (GEH), and their contractors, pursuant... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards Meeting of the ACRS Subcommittee on Future Plant Designs; Revision to the September 24, 2010, ACRS Meeting Federal Register Notice...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-02
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the Subcommittee on Plant Operations and Fire Protection The ACRS Subcommittee on Plant Operations and Fire Protection will hold a meeting on July 29, 2010, at the U.S. NRC Region IV, Texas Health Resources Tower, 612...
-
78 FR 2694 - Meeting of the ACRS Subcommittee on Planning and Procedures; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-14
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS Subcommittee on Planning and Procedures; Notice of Meeting The ACRS Subcommittee on Planning and Procedures..., Advisory Committee on Reactor Safeguards. [FR Doc. 2013-00543 Filed 1-11-13; 8:45 am] BILLING CODE 7590-01...
-
75 FR 13611 - Meeting of the ACRS Subcommittee on Reliability and PRA; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-22
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS... rescheduling would result in major inconvenience. Dated: March 15, 2010. Antonio F. Dias, Chief, Reactor Safety Branch B, Advisory Committee on Reactor Safeguards. [FR Doc. 2010-6203 Filed 3-19-10; 8:45 am] BILLING...
-
10 CFR 1.13 - Advisory Committee on Reactor Safeguards.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 1 2011-01-01 2011-01-01 false Advisory Committee on Reactor Safeguards. 1.13 Section 1... Headquarters Panels, Boards, and Committees § 1.13 Advisory Committee on Reactor Safeguards. The Advisory Committee on Reactor Safeguards (ACRS) was established by section 29 of the Atomic Energy Act of 1954, as...
-
10 CFR 1.13 - Advisory Committee on Reactor Safeguards.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 1 2010-01-01 2010-01-01 false Advisory Committee on Reactor Safeguards. 1.13 Section 1... Headquarters Panels, Boards, and Committees § 1.13 Advisory Committee on Reactor Safeguards. The Advisory Committee on Reactor Safeguards (ACRS) was established by section 29 of the Atomic Energy Act of 1954, as...
-
76 FR 64126 - Advisory Committee on Reactor Safeguards; Procedures for Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-17
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards; Procedures for Meetings.... Nuclear Regulatory Commission's (NRC's) Advisory Committee on Reactor Safeguards (ACRS) pursuant to the... specified in the Federal Register Notice, care of the Advisory Committee on Reactor Safeguards, U.S. Nuclear...
-
78 FR 67205 - Advisory Committee on Reactor Safeguards; Procedures for Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-08
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards; Procedures for Meetings.... Nuclear Regulatory Commission's (NRC's) Advisory Committee on Reactor Safeguards (ACRS) pursuant to the... specified in the Federal Register Notice, care of the Advisory Committee on Reactor Safeguards, U.S. Nuclear...
-
75 FR 21046 - Advisory Committee on Reactor Safeguards
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-22
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards In accordance with the... on Reactor Safeguards (ACRS) will hold a meeting on May 6-8, 2010, 11545 Rockville Pike, Rockville....: Boiling Water Reactor (BWR) Owners Group (BWROG) Topical Report NEDC-33347P, ``Containment Overpressure...
-
75 FR 8154 - Advisory Committee on Reactor Safeguards
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-23
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards In accordance with the... on Reactor Safeguards (ACRS) will hold a meeting on March 4-6, 2010, 11545 Rockville Pike, Rockville....-12 p.m.: New Advanced Reactor Designs (Open)--The Committee will hear presentations by and hold...
-
75 FR 3501 - Advisory Committee on Reactor Safeguards
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-21
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards In accordance with the purposes of Sections 29 and 182b of the Atomic Energy Act (42 U.S.C. 2039, 2232b), the Advisory Committee on Reactor Safeguards (ACRS) will hold a meeting on February 4-6, 2010, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-17
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the ACRS, Subcommittee on U.S. Evolutionary Power Reactor; Notice of Meeting The ACRS Subcommittee on U.S. Evolutionary Power Reactor (U.S. EPR) will hold a meeting on January 17, 2013, Room T-2B1, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-05
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS) Meeting of the Joint ACRS Subcommittees on Thermal Hydraulic Phenomena and Materials, Metallurgy and Reactor Fuels; Notice... Reactor Fuels will hold a meeting on February 20, 2013, Room T-2B1, 11545 Rockville Pike, Rockville...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-04
.... ``Guidance on the Treatment of Uncertainties Associated with PRAs in Risk-Informed Decision Making.'' The... procedures for the conduct of and participation in ACRS meetings were published in the Federal Register on...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-24
... Renewal Application and the associated Safety Evaluation Report (SER) with Open Items prepared by the... participation in ACRS meetings were published in the Federal Register on October 14, 2009 (74 FR 58268-58269...
-
77 FR 64563 - Advisory Committee on Reactor Safeguards; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-22
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards; Notice of Meeting In... Advisory Committee on Reactor Safeguards (ACRS) will hold a meeting on November 1-3, 2012, 11545 Rockville...-Term Core Cooling Approach for the Advanced Boiling Water Reactor (ABWR) Design for South Texas Project...
-
76 FR 79229 - Advisory Committee on Reactor Safeguards; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-21
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards; Notice of Meeting In... Advisory Committee on Reactor Safeguards (ACRS) will hold a meeting on January 19-20, 2012, 11545 Rockville... Cooling Systems for Light- Water Nuclear Power Reactors'' (Open)--The Committee will hear presentations by...
-
77 FR 69900 - Advisory Committee on Reactor Safeguards; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-21
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards; Notice of Meeting In... Advisory Committee on Reactor Safeguards (ACRS) will hold a meeting on December 6-8, 2012, 11545 Rockville... Recommendations (SECY-12-0064), (3) Venting Systems for Boiling Water Reactors (BWRs) with Mark I and Mark II...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-01
... Subcommittee on Thermal-Hydraulics Phenomena; Notice of Meeting The ACRS Subcommittee on Thermal-Hydraulics... Regulatory Guide (1.79), ``Preoperational Testing of Emergency Core Cooling Systems for Pressurized Water... Water Reactors.'' The Subcommittee will hear presentations by and hold discussions with the NRC staff...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-23
... Modeling Application Guide.'' The Subcommittee will hear presentations by and hold discussions with the NRC staff and other interested persons regarding this matter. The Subcommittee will gather information.../acrs . Information regarding topics to be discussed, changes to the agenda, whether the meeting has...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-13
... Subcommittee on Digital Instrumentation and Control Systems; Notice of Meeting The ACRS Subcommittee on Digital... briefing on the results and status of new NRC nuclear power plant digital system research activities which deal with Inventory and Certification of digital systems, operating experience for digital systems, and...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-27
... Subcommittee on Materials, Metallurgy & Reactor Fuels; Notice of Meeting The ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels will hold a meeting on January 14, 2014, Room T-2B1, 11545 Rockville Pike... NRC's research activities in materials and metallurgy. The Subcommittee will hear presentations by and...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-04
... as technical reports related to the Gas Turbine Generator design. The Subcommittee will hear... Subcommittee on United States-Advanced Pressurized Water Reactor (US-APWR); Notice of Meeting The ACRS Subcommittee on United States-Advanced Pressurized Water Reactor (US-APWR) will hold a meeting on April 22...
-
78 FR 32279 - Advisory Committee On Reactor Safeguards; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-29
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards; Notice of Meeting In accordance with the purposes of Sections 29 and 182b of the Atomic Energy Act (42 U.S.C. 2039, 2232b), the Advisory Committee on Reactor Safeguards (ACRS) will hold a meeting on June 5-7, 2013, 11545 Rockville Pike...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-08
... Subcommittee on Reliability and Probabilistic Risk Assessment The ACRS Subcommittee on Reliability and Probabilistic Risk Assessment (PRA) will hold a meeting on September 20, 2011, Room T-2B1, 11545 Rockville Pike... Memorandum on Modifying the Risk-Informed Regulatory Guidance for New Reactors. The Subcommittee will hear...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-19
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Planning and Procedures The ACRS Subcommittee on Planning and Procedures will hold a meeting on May 5, 2010, in Room T-2B1, at 11545 Rockville Pike, Rockville, MD. The entire meeting will be open to...
-
75 FR 66168 - Seeks Qualified Candidates for the Advisory Committee on Reactor Safeguards
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-27
... NUCLEAR REGULATORY COMMISSION Seeks Qualified Candidates for the Advisory Committee on Reactor... Reactor Safeguards (ACRS). Submit r[eacute]sum[eacute]s to Ms. Brandi Hamilton, ACRS, Mail Stop T2E-26, U... of existing and proposed nuclear power plants and on the adequacy of proposed reactor safety...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-28
... Subcommittee On Digital I&C Systems The ACRS Subcommittee on Digital Instrumentation and Control (DI&C) Systems... the area of Digital Instrumentation and Control (DI&C) Probabilistic Risk Assessment (PRA). Topics... software reliability methods (QSRMs), NUREG/CR--6997, ``Modeling a Digital Feedwater Control System Using...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-19
... Subcommittee on Digital I&C; Notice of Meeting The ACRS Subcommittee on Digital I&C will hold a briefing on..., 2013-8:30 a.m. until 5:00 p.m. The Subcommittee will review the results and status of NRC research... handout should be provided to the DFO thirty minutes before the meeting. In addition, one electronic copy...
-
75 FR 4428 - Advisory Committee On Reactor Safeguards; Revised Meeting Notice
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-27
... NUCLEAR REGULATORY COMMISSION Advisory Committee On Reactor Safeguards; Revised Meeting Notice The Agenda for the 569th ACRS meeting, scheduled to be held on February 4-6, 2010, has been revised as noted below. Notice of this meeting was previously published in the Federal Register on Thursday, January 21...
-
75 FR 72844 - Advisory Committee on Reactor Safeguards; Revised Meeting Notice
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-26
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards; Revised Meeting Notice The Agenda for the 578th ACRS meeting, scheduled to be held on December 2-4, 2010, has been revised as noted below. Notice of this meeting was previously published in the Federal Register on Wednesday, November 17...
-
ERIC Educational Resources Information Center
Peckover, Sue
2013-01-01
This study examines the location of British health visiting in contemporary policy discourses concerned with public health and safeguarding children. It argues that professional identity and orientation can be understood through health visiting's long history of public health work with children and families, which has included an engagement with…
-
76 FR 61118 - Advisory Committee on Reactor Safeguards; Revised Meeting Notice
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-03
... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards; Revised Meeting Notice The Agenda for the 587th ACRS meeting, scheduled to be held on October 6-8, 2011, has been revised as noted below. Notice of this meeting was previously published in the Federal Register on September 26, 2011 (76...
-
Expression of acrA and acrB Genes in Esherichia coli Mutants with or without marR or acrR Mutations
Pourahmad Jaktaji, Razieh; Jazayeri, Nasim
2013-01-01
Objective(s): The major antibiotic efflux pump of Esherichia coli is AcrAB-TolC. The first part of the pump, AcrAB, is encoded by acrAB operon. The expression of this operon can be kept elevated by overexpression of an activator, MarA following inactivation of MarR and AcrR repressors due to mutation in encoding genes, marR and acrR, respectively. The aims of this research were to use E. coli mutants with or without mutation in marR to search for the presence of possible mutation in acrR and to quantify the expression of acrAB. Materials and Methods: The DNA binding region of acrR gene in these mutants were amplified by PCR and sequenced. The relative expression of acrA and acrB were determined by real time PCR. Results: Results showed that W26 and C14 had the same mutation in acrR, but none of the mutants overexpressed acrA and acrB in comparison with wild type strain. Conclusions: The effect of marR or acrR mutation on acrAB overexpression is dependent on levels of resistance to tetracycline and ciprofloxacin. PMID:24570831
-
Expression of acrA and acrB Genes in Esherichia coli Mutants with or without marR or acrR Mutations.
Pourahmad Jaktaji, Razieh; Jazayeri, Nasim
2013-12-01
The major antibiotic efflux pump of Esherichia coli is AcrAB-TolC. The first part of the pump, AcrAB, is encoded by acrAB operon. The expression of this operon can be kept elevated by overexpression of an activator, MarA following inactivation of MarR and AcrR repressors due to mutation in encoding genes, marR and acrR, respectively. The aims of this research were to use E. coli mutants with or without mutation in marR to search for the presence of possible mutation in acrR and to quantify the expression of acrAB. The DNA binding region of acrR gene in these mutants were amplified by PCR and sequenced. The relative expression of acrA and acrB were determined by real time PCR. RESULTS showed that W26 and C14 had the same mutation in acrR, but none of the mutants overexpressed acrA and acrB in comparison with wild type strain. The effect of marR or acrR mutation on acrAB overexpression is dependent on levels of resistance to tetracycline and ciprofloxacin.
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-23
... Compliance with Packaging Requirements for Shipment and Receipt of Radioactive Material.'' The Subcommittee... Subcommittee on Radiation Protection and Nuclear Materials; Notice of Meeting The ACRS Subcommittee on Radiation Protection and Nuclear Materials will hold a meeting on January 18, 2012, Room T-2B3, 11545...
-
10 CFR 71.11 - Protection of Safeguards Information.
Code of Federal Regulations, 2012 CFR
2012-01-01
... public health and safety or the common defense and security, shall protect Safeguards Information against... 10 Energy 2 2012-01-01 2012-01-01 false Protection of Safeguards Information. 71.11 Section 71.11... General Provisions § 71.11 Protection of Safeguards Information. Each licensee, certificate holder, or...
-
10 CFR 71.11 - Protection of Safeguards Information.
Code of Federal Regulations, 2011 CFR
2011-01-01
... public health and safety or the common defense and security, shall protect Safeguards Information against... 10 Energy 2 2011-01-01 2011-01-01 false Protection of Safeguards Information. 71.11 Section 71.11... General Provisions § 71.11 Protection of Safeguards Information. Each licensee, certificate holder, or...
-
10 CFR 71.11 - Protection of Safeguards Information.
Code of Federal Regulations, 2010 CFR
2010-01-01
... public health and safety or the common defense and security, shall protect Safeguards Information against... 10 Energy 2 2010-01-01 2010-01-01 false Protection of Safeguards Information. 71.11 Section 71.11... General Provisions § 71.11 Protection of Safeguards Information. Each licensee, certificate holder, or...
-
10 CFR 71.11 - Protection of Safeguards Information.
Code of Federal Regulations, 2013 CFR
2013-01-01
... public health and safety or the common defense and security, shall protect Safeguards Information against... 10 Energy 2 2013-01-01 2013-01-01 false Protection of Safeguards Information. 71.11 Section 71.11... General Provisions § 71.11 Protection of Safeguards Information. Each licensee, certificate holder, or...
-
45 CFR 164.310 - Physical safeguards.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 1 2011-10-01 2011-10-01 false Physical safeguards. 164.310 Section 164.310... Information § 164.310 Physical safeguards. A covered entity must, in accordance with § 164.306: (a)(1) Standard: Facility access controls. Implement policies and procedures to limit physical access to its...
-
45 CFR 164.310 - Physical safeguards.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 1 2012-10-01 2012-10-01 false Physical safeguards. 164.310 Section 164.310... Information § 164.310 Physical safeguards. A covered entity must, in accordance with § 164.306: (a)(1) Standard: Facility access controls. Implement policies and procedures to limit physical access to its...
-
45 CFR 164.310 - Physical safeguards.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 1 2013-10-01 2013-10-01 false Physical safeguards. 164.310 Section 164.310... Information § 164.310 Physical safeguards. A covered entity or business associate must, in accordance with... physical access to its electronic information systems and the facility or facilities in which they are...
-
45 CFR 164.310 - Physical safeguards.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 1 2010-10-01 2010-10-01 false Physical safeguards. 164.310 Section 164.310... Information § 164.310 Physical safeguards. A covered entity must, in accordance with § 164.306: (a)(1) Standard: Facility access controls. Implement policies and procedures to limit physical access to its...
-
45 CFR 164.310 - Physical safeguards.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 1 2014-10-01 2014-10-01 false Physical safeguards. 164.310 Section 164.310... Information § 164.310 Physical safeguards. A covered entity or business associate must, in accordance with... physical access to its electronic information systems and the facility or facilities in which they are...
-
Update Of The ACR-NEMA Standard Committee
NASA Astrophysics Data System (ADS)
Wang, Yen; Best, D. E.; Morse, R. R.; Horii, S. C.; Lehr, J. L.; Lodwick, G. S.; Fuscoe, C.; Nelson, O. L.; Perry, J. R.; Thompson, B. G.; Wessell, W. R.
1988-06-01
In January, 1984, the American College of Radiology (ACR) representing the users of imaging equipment and the National Electrical Manufacturers Association (NEMA) representing the manufacturers of imaging equipment joined forces to create a committee that could solve the compatibility issues surrounding the exchange of digital medical images. This committee, the ACR-NEMA Digital Imaging and Communication Standards Committee was composed of radiologists and experts from industry who addressed the problems involved in interfacing different digital imaging modalities. In just two years, the committee and three of its working groups created an industry standard interface, ACR-NEMA Digital Imaging and Communications Standard, Publication No. 300-1985. The ACR-NEMA interface allows digital medical images and related information to be communicated between different imaging devices, regardless of manufacturer or use of differing image formats. The interface is modeled on the International Standards Organization's Open Systems Interconnection sever-layer reference model. It is believed that the development of the Interface was the first step in the development of standards for Medical Picture Archiving and Communications Systems (PACS). Developing the interface Standard has required intensive technical analysis and examination of the future trends for digital imaging in order to design a model which would not be quickly outmoded. To continue the enhancement and future development of image management systems, various working groups have been created under the direction of the ACR-NEMA Committee.
-
45 CFR 605.36 - Procedural safeguards.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION... Preschool, Elementary, and Secondary Education § 605.36 Procedural safeguards. A recipient that operates a public elementary or secondary education program shall establish and implement, with respect to actions...
-
45 CFR 605.36 - Procedural safeguards.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION... Preschool, Elementary, and Secondary Education § 605.36 Procedural safeguards. A recipient that operates a public elementary or secondary education program shall establish and implement, with respect to actions...
-
45 CFR 605.36 - Procedural safeguards.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION... Preschool, Elementary, and Secondary Education § 605.36 Procedural safeguards. A recipient that operates a public elementary or secondary education program shall establish and implement, with respect to actions...
-
45 CFR 605.36 - Procedural safeguards.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION... Preschool, Elementary, and Secondary Education § 605.36 Procedural safeguards. A recipient that operates a public elementary or secondary education program shall establish and implement, with respect to actions...
-
42 CFR 431.305 - Types of information to be safeguarded.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 42 Public Health 4 2011-10-01 2011-10-01 false Types of information to be safeguarded. 431.305... Information on Applicants and Recipients § 431.305 Types of information to be safeguarded. (a) The agency must have criteria that govern the types of information about applicants and recipients that are safeguarded...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-11
... Subcommittee on Reliability and PRA; Revision to March 24, 2010, ACRS Meeting Federal Register Notice The... scheduled to be held on March 24, 2011, has been cancelled. The notice of this meeting was previously published in the Federal Register on Wednesday, March 2, 2011, [75 FR 11525]. Further information regarding...
-
42 CFR 438.58 - Conflict of interest safeguards.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 4 2010-10-01 2010-10-01 false Conflict of interest safeguards. 438.58 Section 438... (CONTINUED) MEDICAL ASSISTANCE PROGRAMS MANAGED CARE State Responsibilities § 438.58 Conflict of interest... safeguards against conflict of interest on the part of State and local officers and employees and agents of...
-
45 CFR 164.312 - Technical safeguards.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 1 2014-10-01 2014-10-01 false Technical safeguards. 164.312 Section 164.312 Public Welfare Department of Health and Human Services ADMINISTRATIVE DATA STANDARDS AND RELATED REQUIREMENTS SECURITY AND PRIVACY Security Standards for the Protection of Electronic Protected Health...
-
41 CFR 109-28.306-5 - Safeguards.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Safeguards. 109-28.306-5 Section 109-28.306-5 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF ENERGY PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 28-STORAGE...
-
42 CFR 431.305 - Types of information to be safeguarded.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 42 Public Health 4 2013-10-01 2013-10-01 false Types of information to be safeguarded. 431.305... Information on Applicants and Beneficiaries § 431.305 Types of information to be safeguarded. (a) The agency must have criteria that govern the types of information about applicants and beneficiaries that are...
-
Lessons Learned: Public Health Nurses Practice in Safeguarding Children in the Republic of Ireland.
Phelan, Amanda; Davis, Michaela
2015-01-01
The public health nurses' scope of practice explicitly includes child protection within their role, which places them in a prime position to identify child protection concerns. This role compliments that of other professions and voluntary agenices who work with children. Public health nurses are in a privileged position as they form a relationship with the child's parent(s)/guardian(s) and are able to see the child in its own environment, which many professionals cannot. Child protection in Ireland, while influenced by other countries, has progressed through a distinct pathway that streamlined protocols and procedures. However, despite the above serious failures have occurred in the Irish system, and inquiries over the past 20 years persistently present similar contributing factors, namely, the lack of standardized and comprehensive service responses. Moreover, poor practice is compounded by the lack of recognition of the various interactional processes taking place within and between the different agencies of child protection, leading to psychological barriers in communication. This article will explore the lessons learned for public health nurses practice in safeguarding children in the Republic of Ireland.
-
45 CFR 400.27 - Safeguarding and sharing of information.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 2 2010-10-01 2010-10-01 false Safeguarding and sharing of information. 400.27 Section 400.27 Public Welfare Regulations Relating to Public Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM...
-
Coarse-grained Simulations of Substrate Export through Multidrug Efflux Transporter AcrB
NASA Astrophysics Data System (ADS)
Jewel, Yead; Dutta, Prashanta; Liu, Jin
2017-11-01
The treatment of bacterial infectious diseases hampered by the overexpression of multidrug resistance (MDR) systems. The MDR system actively pumps the antibiotic drugs as well as other toxic compounds out of the cells. During the pumping, AcrB (one of the key MDR components) undergoes a series of large-scale proton/substrate dependent conformational changes. In this work, we implement a hybrid coarse-grained PACE force field that couples the united-atom protein model with the coarse-grained MARTINI water/lipid, to investigate the conformational changes of AcrB. We first develop the substrate force field which is compatible with PACE, then we implement the force field to explore large scale structural changes of AcrB in microsecond simulations. The effects of the substrate and the protonation states of two key residues: Asp407 and Asp408, are investigated. Our results show that the drug export through AcrB is proton as well as substrate dependent. Our simulations explain molecular mechanisms of substrate transport through AcrB complex, as well as provide valuable insights for designing proper antibiotic drugs. Research reported in this publication was supported by the National Institute of General Medical Sciences of the National Institutes of Health under Award Number R01GM122081.
-
An expanded safeguards role for the DOE safeguards analytical laboratory
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bingham, C.D.
The New Brunswick Laboratory (NBL) is a Government-owned, Government-operated (GOGO) laboratory, with the mission to provide and maintain a nuclear material measurements and standards laboratory. The functional responsibilities of NBL serve as a technical response to the statutory responsibility of the Department of Energy (DOE) to assure the safeguarding of nuclear materials. In the execution of its mission, NBL carries out activities in six safeguards-related programs: measurement development, measurement evaluation, measurement services, safeguards assessment, reference and calibration materials and site-specific assistance. These program activities have been implemented by NBL for many years; their relative emphases, however, have been changed recentlymore » to address the priorities defined by the DOE Office of Safeguards and Security, Defense Programs (OSS/DP). As a consequence, NBL operations are in the ''mainstream'' of domestic safeguards activities. This expanded safeguards role for NBL is discussed in this paper.« less
-
MO-AB-207-02: ACR Update in MR
DOE Office of Scientific and Technical Information (OSTI.GOV)
Price, R.
2015-06-15
A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date asmore » the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.« less
-
MO-AB-207-04: ACR Update in Mammography
DOE Office of Scientific and Technical Information (OSTI.GOV)
Berns, E.
2015-06-15
A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date asmore » the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.« less
-
MO-AB-207-01: ACR Update in CT
DOE Office of Scientific and Technical Information (OSTI.GOV)
McNitt-Gray, M.
2015-06-15
A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date asmore » the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.« less
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-13
...-3, 2010, 11545 Rockville Pike, Room T2-B1, Rockville, Maryland. The meeting will be open to public... the Draft Safety Evaluation Report associated with the amendment to the Westinghouse AP1000 Design...
-
45 CFR 205.50 - Safeguarding information for the financial assistance programs.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 2 2013-10-01 2012-10-01 true Safeguarding information for the financial assistance programs. 205.50 Section 205.50 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH...
-
45 CFR 205.50 - Safeguarding information for the financial assistance programs.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 2 2012-10-01 2012-10-01 false Safeguarding information for the financial assistance programs. 205.50 Section 205.50 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH...
-
45 CFR 205.50 - Safeguarding information for the financial assistance programs.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 2 2014-10-01 2012-10-01 true Safeguarding information for the financial assistance programs. 205.50 Section 205.50 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH...
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Frazar, Sarah L.; Gastelum, Zoe N.; Olson, Jarrod
2009-10-06
The U.S. Department of Energy/National Nuclear Security Administration (DOE/NNSA) hosted a workshop from May 4-22, 2009, on the fundamental elements of international safeguards. Entitled "A Technical Training Workshop on International Safeguards," the workshop introduced post-graduate students from Malaysia, Vietnam, Indonesia, Thailand, Morocco, Egypt, Algeria and Tunisia to the fundamental issues and best practices associated with international safeguards and encouraged them to explore potential career paths in safeguards. Workshops like these strengthen the international safeguards regime by promoting the development of a "safeguards culture" among young nuclear professionals within nascent nuclear countries. While this concept of safeguards culture is sometimes hardmore » to define and even harder to measure, this paper will demonstrate that the promotion of safeguards cultures through workshops like these justifies the investment of U.S. taxpayer dollars.« less
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Toquam, J.L.; Morris, F.A.
This is the second of two reports prepared to assist the International Atomic Energy Agency (IAEA or Agency) in enhancing the effectiveness of its international safeguards inspections through inspector training in {open_quotes}Observational Skills{close_quotes}. The first (Phase 1) report was essentially exploratory. It defined Observational Skills broadly to include all appropriate cognitive, communications, and interpersonal techniques that have the potential to help IAEA safeguards inspectors function more effectively. It identified 10 specific Observational Skills components, analyzed their relevance to IAEA safeguards inspections, and reviewed a variety of inspection programs in the public and private sectors that provide training in one ormore » more of these components. The report concluded that while it should be possible to draw upon these other programs in developing Observational Skills training for IAEA inspectors, the approaches utilized in these programs will likely require significant adaption to support the specific job requirements, policies, and practices that define the IAEA inspector`s job. The overall objective of this second (Phase 2) report is to provide a basis for the actual design and delivery of Observational Skills training to IAEA inspectors. The more specific purposes of this report are to convey a fuller understanding of the potential application of Observational Skills to the inspector`s job, describe inspector perspectives on the relevance and importance of particular Observational Skills, identify the specific Observational Skill components that are most important and relevant to enhancing safeguards inspections, and make recommendations as to Observational Skills training for the IAEA`s consideration in further developing its Safeguards training program.« less
-
MO-AB-207-03: ACR Update in Nuclear Medicine
DOE Office of Scientific and Technical Information (OSTI.GOV)
Harkness, B.
A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date asmore » the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.« less
-
7 CFR 1412.21 - Election of base acres.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 10 2011-01-01 2011-01-01 false Election of base acres. 1412.21 Section 1412.21... CROP REVENUE ELECTION PROGRAM FOR THE 2008 AND SUBSEQUENT CROP YEARS Establishment of Base Acres for a Farm for Covered Commodities § 1412.21 Election of base acres. (a) Subject to adjustments in paragraph...
-
7 CFR 1412.21 - Election of base acres.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 10 2013-01-01 2013-01-01 false Election of base acres. 1412.21 Section 1412.21... CROP REVENUE ELECTION PROGRAM FOR THE 2008 AND SUBSEQUENT CROP YEARS Establishment of Base Acres for a Farm for Covered Commodities § 1412.21 Election of base acres. (a) Subject to adjustments in paragraph...
-
7 CFR 1412.21 - Election of base acres.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 10 2012-01-01 2012-01-01 false Election of base acres. 1412.21 Section 1412.21... CROP REVENUE ELECTION PROGRAM FOR THE 2008 AND SUBSEQUENT CROP YEARS Establishment of Base Acres for a Farm for Covered Commodities § 1412.21 Election of base acres. (a) Subject to adjustments in paragraph...
-
7 CFR 1412.21 - Election of base acres.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 10 2010-01-01 2010-01-01 false Election of base acres. 1412.21 Section 1412.21... CROP REVENUE ELECTION PROGRAM FOR THE 2008 AND SUBSEQUENT CROP YEARS Establishment of Base Acres for a Farm for Covered Commodities § 1412.21 Election of base acres. (a) Subject to adjustments in paragraph...
-
7 CFR 1412.44 - Notification of base acres.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 10 2012-01-01 2012-01-01 false Notification of base acres. 1412.44 Section 1412.44... through 2012 § 1412.44 Notification of base acres. The operator and owners of record of a farm will be notified in writing of the number of base acres eligible for enrollment in a contract, unless such operator...
-
7 CFR 1412.44 - Notification of base acres.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 10 2011-01-01 2011-01-01 false Notification of base acres. 1412.44 Section 1412.44... through 2012 § 1412.44 Notification of base acres. The operator and owners of record of a farm will be notified in writing of the number of base acres eligible for enrollment in a contract, unless such operator...
-
7 CFR 1412.44 - Notification of base acres.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 10 2013-01-01 2013-01-01 false Notification of base acres. 1412.44 Section 1412.44... Through 2012 § 1412.44 Notification of base acres. The operator and owners of record of a farm will be notified in writing of the number of base acres eligible for enrollment in a contract, unless such operator...
-
7 CFR 1412.44 - Notification of base acres.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 10 2010-01-01 2010-01-01 false Notification of base acres. 1412.44 Section 1412.44... through 2012 § 1412.44 Notification of base acres. The operator and owners of record of a farm will be notified in writing of the number of base acres eligible for enrollment in a contract, unless such operator...
-
41 CFR 105-64.108 - How does GSA safeguard personal information?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How does GSA safeguard personal information? 105-64.108 Section 105-64.108 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General...
-
Permitting program with best management practices for shale gas wells to safeguard public health.
Centner, Terence J; Petetin, Ludivine
2015-11-01
The development of shale gas resources in the United States has been controversial as governments have been tardy in devising sufficient safeguards to protect both people and the environment. Alleged health and environmental damages suggest that other countries around the world that decide to develop their shale gas resources can learn from these problems and take further actions to prevent situations resulting in the release of harmful pollutants. Looking at U.S. federal regulations governing large animal operations under the permitting provisions of the Clean Water Act, the idea of a permitting program is proposed to respond to the risks of pollution by shale gas development activities. Governments can require permits before allowing the drilling of a new gas well. Each permit would include fluids and air emissions reduction plans containing best management practices to minimize risks and releases of pollutants. The public availability of permits and permit applications, as occurs for water pollution under various U.S. permitting programs, would assist governments in protecting public health. The permitting proposals provide governments a means for providing further assurances that shale gas development projects will not adversely affect people and the environment. Copyright © 2015 Elsevier Ltd. All rights reserved.
-
7 CFR 1412.23 - Base acres and Conservation Reserve Program.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 10 2012-01-01 2012-01-01 false Base acres and Conservation Reserve Program. 1412.23... Base Acres for a Farm for Covered Commodities § 1412.23 Base acres and Conservation Reserve Program. (a... year, adjust the base acres for covered commodities and peanuts with respect to the farm by the number...
-
7 CFR 1412.23 - Base acres and Conservation Reserve Program.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 10 2011-01-01 2011-01-01 false Base acres and Conservation Reserve Program. 1412.23... Base Acres for a Farm for Covered Commodities § 1412.23 Base acres and Conservation Reserve Program. (a... year, adjust the base acres for covered commodities and peanuts with respect to the farm by the number...
-
7 CFR 1412.23 - Base acres and Conservation Reserve Program.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 10 2010-01-01 2010-01-01 false Base acres and Conservation Reserve Program. 1412.23... Base Acres for a Farm for Covered Commodities § 1412.23 Base acres and Conservation Reserve Program. (a... year, adjust the base acres for covered commodities and peanuts with respect to the farm by the number...
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Frazar, Sarah L.; Winters, Samuel T.; Kreyling, Sean J.
In 2016, the Office of International Nuclear Safeguards at the National Nuclear Security Administration (NNSA) within the Department of Energy (DOE) commissioned the Pacific Northwest National Laboratory (PNNL) to explore the potential implications of the digital currency bitcoin and its underlying technologies on the safeguards system. The authors found that one category of technologies referred to as Shared Ledger Technology (SLT) offers a spectrum of benefits to the safeguards system. While further research is needed to validate assumptions and findings in the paper, preliminary analysis suggests that both the International Atomic Energy Agency (IAEA) and Member States can use SLTmore » to promote efficient, effective, accurate, and timely reporting, and increase transparency in the safeguards system without sacrificing confidentiality of safeguards data. This increased transparency and involvement of Member States in certain safeguards transactions could lead to increased trust and cooperation among States and the public, which generates a number of benefits. This paper describes these benefits and the analytical framework for assessing SLT applications for specific safeguards problems. The paper will also describe other national security areas where SLT could provide benefits.« less
-
The Automated Conflict Resolution System (ACRS)
NASA Technical Reports Server (NTRS)
Kaplan, Ted; Musliner, Andrew; Wampler, David
1993-01-01
The Automated Conflict Resolution System (ACRS) is a mission-current scheduling aid that predicts periods of mutual interference when two or more orbiting spacecraft are scheduled to communicate with the same Tracking and Data Relay Satellite (TDRS) at the same time. The mutual interference predicted has the potential to degrade or prevent communications. Thus the ACRS system is a useful tool for aiding in the scheduling of Space Network (SN) communications.
-
The Automated Conflict Resolution System (ACRS)
NASA Astrophysics Data System (ADS)
Kaplan, Ted; Musliner, Andrew; Wampler, David
1993-11-01
The Automated Conflict Resolution System (ACRS) is a mission-current scheduling aid that predicts periods of mutual interference when two or more orbiting spacecraft are scheduled to communicate with the same Tracking and Data Relay Satellite (TDRS) at the same time. The mutual interference predicted has the potential to degrade or prevent communications. Thus the ACRS system is a useful tool for aiding in the scheduling of Space Network (SN) communications.
-
Cho, Seon; Kim, Suyoung; Cho, Han-Ik
2017-01-01
Background Albuminuria is generally known as a sensitive marker of renal and cardiovascular dysfunction. It can be used to help predict the occurrence of nephropathy and cardiovascular disorders in diabetes. Individuals with prediabetes have a tendency to develop macrovascular and microvascular pathology, resulting in an increased risk of retinopathy, cardiovascular diseases, and chronic renal diseases. We evaluated the clinical value of a strip test for measuring the urinary albumin-to-creatinine ratio (ACR) in prediabetes and diabetes. Methods Spot urine samples were obtained from 226 prediabetic and 275 diabetic subjects during regular health checkups. Urinary ACR was measured by using strip and laboratory quantitative tests. Results The positive rates of albuminuria measured by using the ACR strip test were 15.5% (microalbuminuria, 14.6%; macroalbuminuria, 0.9%) and 30.5% (microalbuminuria, 25.1%; macroalbuminuria, 5.5%) in prediabetes and diabetes, respectively. In the prediabetic population, the sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy of the ACR strip method were 92.0%, 94.0%, 65.7%, 99.0%, and 93.8%, respectively; the corresponding values in the diabetic population were 80.0%, 91.6%, 81.0%, 91.1%, and 88.0%, respectively. The median [interquartile range] ACR values in the strip tests for measurement ranges of <30, 30-300, and >300 mg/g were 9.4 [6.3-15.4], 46.9 [26.5-87.7], and 368.8 [296.2-575.2] mg/g, respectively, using the laboratory method. Conclusions The ACR strip test showed high sensitivity, specificity, and negative predictive value, suggesting that the test can be used to screen for albuminuria in cases of prediabetes and diabetes. PMID:27834062
-
Heidary, Mohsen; Bahramian, Aghil; Hashemi, Ali; Goudarzi, Mehdi; Omrani, Vahid Fallah; Eslami, Gita; Goudarzi, Hossein
2017-03-01
The distribution of drug resistance among clinical isolates of Escherichia coli and Klebsiella pneumoniae has limited the therapeutic options. The aim of this study was to report the prevalence of quinolone resistance genes among E. coli and K. pneumoniae clinical strains isolated from three educational hospitals of Tehran, Iran. A total of 100 strains of E. coli from Labbafinejad and Taleghani Hospitals and 100 strains of K. pneumoniae from Mofid Children and Taleghani Hospitals were collected between January 2013 and May 2014. Antimicrobial susceptibility tests were done by disk diffusion method based on Clinical and Laboratory Standards Institute guidelines. Detection of qepA, aac(6')-Ib-cr, acrA, and acrB genes was done by polymerase chain reaction (PCR). In this study, fosfomycin and imipenem against E. coli and fosfomycin and tigecycline against K. pneumoniae had the best effect in antimicrobial susceptibility tests. PCR assay using specific primers demonstrated that the prevalence of qepA, aac(6')-Ib-cr, acrA, and acrB genes among the 100 E. coli isolates was 0 (0%), 87 (87%), 92 (92%), and 84 (84%), respectively. The prevalence of qepA, aac(6')-Ib-cr, acrA, and acrB genes among the 100 K. pneumoniae isolates was 4 (4%), 85 (85%), 94 (94%), and 87 (87%), respectively. The distribution of qepA, aac(6')-Ib-cr, acrA, and acrB resistance determinants in E. coli and K. pneumoniae is a great concern. Therefore, infection control and prevention of spread of drug-resistant bacteria need careful management of medication and identification of resistant isolates.
-
A compilation of reports of the Advisory Committee on reactor safeguards. 1996 Annual report
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1997-04-01
This compilation contains 47 ACRS reports submitted to the Commission, or to the Executive Director for Operations, during calendar year 1996. It also includes a report to the Congress on the NRC Safety Research Program. All reports have been made available to the public through the NRC Public Document Room, the U.S. Library of Congress, and the Internet at http://www.nrc.gov/ACRSACNW. The reports are divided into two groups: Part 1 contains ACRS reports by project name and by chronological order within project name. Part 2 categorizes the reports by the most appropriate generic subject area and by chronological order within subjectmore » area.« less
-
Unfolding study of a trimeric membrane protein AcrB.
Ye, Cui; Wang, Zhaoshuai; Lu, Wei; Wei, Yinan
2014-07-01
The folding of a multi-domain trimeric α-helical membrane protein, Escherichia coli inner membrane protein AcrB, was investigated. AcrB contains both a transmembrane domain and a large periplasmic domain. Protein unfolding in sodium dodecyl sulfate (SDS) and urea was monitored using the intrinsic fluorescence and circular dichroism spectroscopy. The SDS denaturation curve displayed a sigmoidal profile, which could be fitted with a two-state unfolding model. To investigate the unfolding of separate domains, a triple mutant was created, in which all three Trp residues in the transmembrane domain were replaced with Phe. The SDS unfolding profile of the mutant was comparable to that of the wild type AcrB, suggesting that the observed signal change was largely originated from the unfolding of the soluble domain. Strengthening of trimer association through the introduction of an inter-subunit disulfide bond had little effect on the unfolding profile, suggesting that trimer dissociation was not the rate-limiting step in unfolding monitored by fluorescence emission. Under our experimental condition, AcrB unfolding was not reversible. Furthermore, we experimented with the refolding of a monomeric mutant, AcrBΔloop , from the SDS unfolded state. The CD spectrum of the refolded AcrBΔloop superimposed well onto the spectra of the original folded protein, while the fluorescence spectrum was not fully recovered. In summary, our results suggested that the unfolding of the trimeric AcrB started with a local structural rearrangement. While the refolding of secondary structure in individual monomers could be achieved, the re-association of the trimer might be the limiting factor to obtain folded wild-type AcrB. © 2014 The Protein Society.
-
Safeguards by Design Challenge
DOE Office of Scientific and Technical Information (OSTI.GOV)
Alwin, Jennifer Louise
The International Atomic Energy Agency (IAEA) defines Safeguards as a system of inspection and verification of the peaceful uses of nuclear materials as part of the Nuclear Nonproliferation Treaty. IAEA oversees safeguards worldwide. Safeguards by Design (SBD) involves incorporation of safeguards technologies, techniques, and instrumentation during the design phase of a facility, rather that after the fact. Design challenge goals are the following: Design a system of safeguards technologies, techniques, and instrumentation for inspection and verification of the peaceful uses of nuclear materials. Cost should be minimized to work with the IAEA’s limited budget. Dose to workers should always bemore » as low are reasonably achievable (ALARA). Time is of the essence in operating facilities and flow of material should not be interrupted significantly. Proprietary process information in facilities may need to be protected, thus the amount of information obtained by inspectors should be the minimum required to achieve the measurement goal. Then three different design challenges are detailed: Plutonium Waste Item Measurement System, Marine-based Modular Reactor, and Floating Nuclear Power Plant (FNPP).« less
-
Safeguards Considerations for Thorium Fuel Cycles
Worrall, Louise G.; Worrall, Andrew; Flanagan, George F.; ...
2016-04-21
We report that by around 2025, thorium-based fuel cycles are likely to be deployed internationally. States such as China and India are pursuing research, development, and deployment pathways toward a number of commercial-scale thorium fuel cycles, and they are already building test reactors and the associated fuel cycle infrastructure. In the future, the potential exists for these emerging programs to sell, export, and deploy thorium fuel cycle technology in other states. Without technically adequate international safeguards protocols and measures in place, any future potential clandestine misuse of these fuel cycles could go undetected, compromising the deterrent value of these protocolsmore » and measures. The development of safeguards approaches for thorium-based fuel cycles is therefore a matter of some urgency. Yet, the focus of the international safeguards community remains mainly on safeguarding conventional 235U- and 239Pu-based fuel cycles while the safeguards challenges of thorium-uranium fuel cycles remain largely uninvestigated. This raises the following question: Is the International Atomic Energy Agency and international safeguards system ready for thorium fuel cycles? Furthermore, is the safeguards technology of today sufficiently mature to meet the verification challenges posed by thorium-based fuel cycles? In defining these and other related research questions, the objectives of this paper are to identify key safeguards considerations for thorium-based fuel cycles and to call for an early dialogue between the international safeguards and the nuclear fuel cycle communities to prepare for the potential safeguards challenges associated with these fuel cycles. In this paper, it is concluded that directed research and development programs are required to meet the identified safeguards challenges and to take timely action in preparation for the international deployment of thorium fuel cycles.« less
-
Women's Leadership in the ACR, 2001-2015.
Patel, Amy K; Fielding, Julia; Macura, Katarzyna J; Applegate, Kimberly E; Zackula, Rosalee; Arleo, Elizabeth Kagan
2017-06-01
To assess the trends of women in voluntary leadership roles in the ACR from 2001 to 2015. Retrospective leadership records from 2001 to 2015 were collected from the ACR Membership Database based on member demographics, gender, and participation in leadership roles at the national and state level. Data were sorted by gender and year to assess the proportion of women in each leadership position relative to total member/representation counts. Overall, there were increasing numbers of women represented in ACR leadership. From 2001 to 2015, there were increasing rates of women achieving fellowship in the College (7%-11%), now at parity with male member rates. Representation by women has risen from 7% to 21% for state chapter presidents and from 14% to 18% for state councilors. Comparing rolling 5-year averages from 2001-2005 and 2011-2015 showed statistically significant increases (P < .05) in these leadership roles. Women members of the council steering committee rose from 13% in 2001 to 19% in 2015, peaking at 24% in 2014. The Board of Chancellors (BOC) showed the largest increase in women, from 9% to 33%, with a peak at 37% in 2014. However, no BOC chairs were women, one council speaker was a woman, two women were ACR presidents, and two women were vice presidents. Women's participation in ACR leadership has increased significantly at the state level and in fellowship recognition. Although there are increasing numbers of women on the BOC, top positions remain male-dominated at the national level. Published by Elsevier Inc.
-
Converting standard seeding rates for grasses to actual seeding rates per acre.
Joseph F. Pechanec
1950-01-01
Standard rates specifying the amount of grass seed to sow per acre are stated in most of the more recent publications as pounds of live pure seed (lps) to be used. For a seeding project these rates must be converted to the actual amount of seed to sow because seed as purchased from the dealer or grower is never all live pure seed. Even the best lots of seed contain...
-
19 CFR 206.36 - Public report.
Code of Federal Regulations, 2013 CFR
2013-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations Relating to Bilateral Safeguard Actions § 206.36 Public report. Upon making...
-
19 CFR 206.36 - Public report.
Code of Federal Regulations, 2014 CFR
2014-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations Relating to Bilateral Safeguard Actions § 206.36 Public report. Upon making...
-
19 CFR 206.36 - Public report.
Code of Federal Regulations, 2012 CFR
2012-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations Relating to Bilateral Safeguard Actions § 206.36 Public report. Upon making...
-
19 CFR 206.36 - Public report.
Code of Federal Regulations, 2011 CFR
2011-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations Relating to Bilateral Safeguard Actions § 206.36 Public report. Upon making...
-
19 CFR 206.36 - Public report.
Code of Federal Regulations, 2010 CFR
2010-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations Relating to Bilateral Safeguard Actions § 206.36 Public report. Upon making...
-
Transmembrane topology of the arsenite permease Acr3 from Saccharomyces cerevisiae.
Wawrzycka, Donata; Markowska, Katarzyna; Maciaszczyk-Dziubinska, Ewa; Migocka, Magdalena; Wysocki, Robert
2017-01-01
Acr3 is a plasma membrane transporter, a member of the bile/arsenite/riboflavin transporter (BART) superfamily, which confers high-level resistance to arsenicals in the yeast Saccharomyces cerevisiae. We have previously shown that the yeast Acr3 acts as a low affinity As(III)/H + and Sb(III)/H + antiporter. We have also identified several amino acid residues that are localized in putative transmembrane helices (TM) and appeared to be critical for the Acr3 activity. In the present study, the topology of Acr3 was investigated by insertion of glycosylation and factor Xa protease cleavage sites at predicted hydrophilic regions. The analysis of the glycosylation pattern and factor Xa cleavage products of resulting Acr3 fusion constructs provide evidence supporting a topological model of Acr3 with 10 TM segments and cytoplasmically oriented N- and C-terminal domains. Next, we investigated the role of the hydrophilic loop connecting TM8 and TM9, the large size of which is unique to members of the yeast Acr3 family of metalloid transporters. We found that a 28 amino acid deletion in this region does not affect Acr3 folding, trafficking substrate binding, or transport activity. Finally, we constructed a homology-based structural model of Acr3 using the crystal structure of the Yersinia frederiksenii homologue of the human bile acid sodium symporter ASBT. Copyright © 2016 Elsevier B.V. All rights reserved.
-
19 CFR 206.19 - Public report.
Code of Federal Regulations, 2013 CFR
2013-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations Relating to Global Safeguard Actions § 206.19 Public report. Upon making a...
-
19 CFR 206.19 - Public report.
Code of Federal Regulations, 2014 CFR
2014-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations Relating to Global Safeguard Actions § 206.19 Public report. Upon making a...
-
19 CFR 206.19 - Public report.
Code of Federal Regulations, 2012 CFR
2012-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations Relating to Global Safeguard Actions § 206.19 Public report. Upon making a...
-
19 CFR 206.19 - Public report.
Code of Federal Regulations, 2010 CFR
2010-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations Relating to Global Safeguard Actions § 206.19 Public report. Upon making a...
-
19 CFR 206.19 - Public report.
Code of Federal Regulations, 2011 CFR
2011-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations Relating to Global Safeguard Actions § 206.19 Public report. Upon making a...
-
acr-23 Encodes a Monepantel-Sensitive Channel in Caenorhabditis elegans
Rufener, Lucien; Bedoni, Nicola; Baur, Roland; Rey, Samantha; Glauser, Dominique A.; Bouvier, Jacques; Beech, Robin; Sigel, Erwin; Puoti, Alessandro
2013-01-01
Monepantel is a member of the recently identified class of anthelmintics known as the amino-acetonitrile derivatives (AADs). Monepantel controls all major gastro-intestinal nematodes in sheep including those that are resistant to the classical anthelmintics. Previous studies have shown that the Caenorhabditis elegans acr-23 and the Haemonchus contortus Hco-mptl-1 genes may be prominent targets of monepantel. With this discovery it became possible to investigate the mode of action of monepantel in nematodes at the molecular level. In the present study, we show that a C. elegans mutant acr-23 strain is fully rescued by expressing the wild-type acr-23 gene. Moreover, we present a new mutant allele, and characterize acr-23 alleles genetically. We also show that acr-23 is expressed in body wall muscle cells, and provide therefore a possible explanation for the paralysis caused by monepantel. Furthermore, genetic evidence suggests that the chaperone RIC-3 is required for expression of full monepantel resistance. Finally, we present reconstitution of the C. elegans ACR-23 receptor in Xenopus laevis oocytes and provide direct evidence of its modulation by monepantel. Conversely, co-injection of the chaperone RIC-3 had no impact for channel reconstitution in X. laevis oocytes. These results reinforce the involvement of the ACR-23 family in the mode of action of monepantel and advance our understanding of this new class of anthelmintics. PMID:23950710
-
Jeong, Hyeongseop; Kim, Jin-Sik; Song, Saemee; Shigematsu, Hideki; Yokoyama, Takeshi; Hyun, Jaekyung; Ha, Nam-Chul
2016-02-02
The resistance-nodulation-division type tripartite pump AcrAB-TolC and its homologs are responsible for multidrug resistance in Gram-negative bacteria by expelling a wide variety of toxic substrates. The three essential components, AcrA, AcrB, and TolC, must function in concert with each respective binding partner within the complex. In this study, we report an 8.2-Å resolution cryo-electron microscopy (cryo-EM) 3D reconstruction of the complex that consists of an AcrAB fusion protein and a chimeric TolC protein. The pseudoatomic structure derived from the cryo-EM reconstruction clearly demonstrates a model only compatible with the adaptor bridging mechanism, wherein the funnel-like AcrA hexamer forms an intermeshing cogwheel-like interaction with the α-barrel tip region of TolC. These observations provide a structural milestone for understanding multidrug resistance in pathogenic Gram-negative bacteria, and may also lead to the design of new antibacterial drugs. Copyright © 2016 Elsevier Ltd. All rights reserved.
-
Nuclear materials safeguards for the future
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tape, J.W.
Basic concepts of domestic and international safeguards are described, with an emphasis on safeguards systems for the fuel cycles of commercial power reactors. Future trends in institutional and technical measures for nuclear materials safeguards are outlined. The conclusion is that continued developments in safeguards approaches and technology, coupled with institutional measures that facilitate the global management and protection of nuclear materials, are up to the challenge of safeguarding the growing inventories of nuclear materials in commercial fuel cycles in technologically advanced States with stable governments that have signed the nonproliferation treaty. These same approaches also show promise for facilitating internationalmore » inspection of excess weapons materials and verifying a fissile materials cutoff convention.« less
-
Defending the social value of knowledge as a safeguard for public trust.
Holzer, Felicitas S
2017-09-01
The 'socially valuable knowledge' (SVK) principle has been widely acknowledged as one of the most important guiding principles for biomedical research involving human subjects. The principle states that the potential of producing socially valuable knowledge is a necessary requirement, although not sufficient, for the ethical conduct of research projects. This is due to the assumption that the social value of knowledge avoids exploitation of research subjects and justifies the use of health resources. However, more recently, several authors have started interrogating the validity of SVK in research and offered various lines of argument against the SVK principle as a necessary constraint to research. In this article, I will reconstruct the main arguments of this discussion between defenders and debunkers of the SVK principle and offer a third way to consider the social value of knowledge in research studies. I will argue that the social value of knowledge can be supported by an independent justification. This justification of the SVK principle addresses the rationality and common interest of researchers. Thus, I will introduce the SVK principle as a safeguarding principle for public trust based on a conceptual framework by Alex John London. My approach justifies keeping the principle as a precautionary and rational requirement for human health research that all rational stakeholders can agree upon. © 2017 John Wiley & Sons Ltd.
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Janssens-Maenhout, Greet; Kusumi, R.; Daures, Pascal A.
2010-06-16
The renaissance of efforts to expand the use of nuclear energy requires the parallel development of a renewed and more sophisticated work force. Growth in the nuclear sector with high standard of safety, safeguards and security requires skilled staff for design, operations, inspections etc. High-quality nuclear technology educational programs are diminished from past years, and the ability of universities to attract students and to meet future staffing requirements of the nuclear industry is becoming seriously compromised. Thus, education and training in nuclear engineering and sciences is one of the cornerstones for the nuclear sector. Teaching in the nuclear field stillmore » seems strongly influenced by national history but it is time to strengthen resources and collaborate. Moreover with the current nuclear security threats it becomes critical that nuclear technology experts master the basic principles not only of safety, but also of nuclear safeguards, nonproliferation and nuclear security. In Europe the European Nuclear Education Network (ENEN) Association has established the certificate 'European Master of Science in Nuclear Engineering (EMSNE)' as the classic nuclear engineering program covering reactor operation and nuclear safety. However, it does not include courses on nonproliferation, safeguards, or dual-use technologies. The lack of education in nuclear safeguards was tackled by the European Safeguards Research and Development Association (ESARDA), through development and implementation of safeguards course modules. Since 2005 the ESARDA Working Group, called the Training and Knowledge Management Working Group, (TKMWG) has worked with the Joint Research Centre (JRC) in Ispra, Italy to organize a Nuclear Safeguards and Nonproliferation course. This five-day course is held each spring at the JRC, and continues to show increasing interest as evidenced by the positive responses of international lecturers and students. The standard set of lectures covers
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Robert Bean; Casey Durst
2009-10-01
This report is the second in a series of guidelines on international safeguards requirements and practices, prepared expressly for the designers of nuclear facilities. The first document in this series is the description of generic international nuclear safeguards requirements pertaining to all types of facilities. These requirements should be understood and considered at the earliest stages of facility design as part of a new process called “Safeguards-by-Design.” This will help eliminate the costly retrofit of facilities that has occurred in the past to accommodate nuclear safeguards verification activities. The following summarizes the requirements for international nuclear safeguards implementation at enrichmentmore » plants, prepared under the Safeguards by Design project, and funded by the U.S. Department of Energy (DOE) National Nuclear Security Administration (NNSA), Office of NA-243. The purpose of this is to provide designers of nuclear facilities around the world with a simplified set of design requirements and the most common practices for meeting them. The foundation for these requirements is the international safeguards agreement between the country and the International Atomic Energy Agency (IAEA), pursuant to the Treaty on the Non-proliferation of Nuclear Weapons (NPT). Relevant safeguards requirements are also cited from the Safeguards Criteria for inspecting enrichment plants, found in the IAEA Safeguards Manual, Part SMC-8. IAEA definitions and terms are based on the IAEA Safeguards Glossary, published in 2002. The most current specification for safeguards measurement accuracy is found in the IAEA document STR-327, “International Target Values 2000 for Measurement Uncertainties in Safeguarding Nuclear Materials,” published in 2001. For this guide to be easier for the designer to use, the requirements have been restated in plainer language per expert interpretation using the source documents noted. The safeguards agreement is
-
Improving the Transparency of IAEA Safeguards Reporting
DOE Office of Scientific and Technical Information (OSTI.GOV)
Toomey, Christopher; Hayman, Aaron M.; Wyse, Evan T.
2011-07-17
In 2008, the Standing Advisory Group on Safeguards Implementation (SAGSI) indicated that the International Atomic Energy Agency's (IAEA) Safeguards Implementation Report (SIR) has not kept pace with the evolution of safeguards and provided the IAEA with a set of recommendations for improvement. The SIR is the primary mechanism for providing an overview of safeguards implementation in a given year and reporting on the annual safeguards findings and conclusions drawn by the Secretariat. As the IAEA transitions to State-level safeguards approaches, SIR reporting must adapt to reflect these evolutionary changes. This evolved report will better reflect the IAEA's transition to amore » more qualitative and information-driven approach, based upon State-as-a-whole considerations. This paper applies SAGSI's recommendations to the development of multiple models for an evolved SIR and finds that an SIR repurposed as a 'safeguards portal' could significantly enhance information delivery, clarity, and transparency. In addition, this paper finds that the 'portal concept' also appears to have value as a standardized information presentation and analysis platform for use by Country Officers, for continuity of knowledge purposes, and the IAEA Secretariat in the safeguards conclusion process. Accompanying this paper is a fully functional prototype of the 'portal' concept, built using commercial software and IAEA Annual Report data.« less
-
MO-AB-207-00: ACR Update in MR, CT, Nuclear Medicine, and Mammography
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date asmore » the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.« less
-
Masoner, J.R.; Mladinich, C.S.; Konduris, A.M.; Smith, S. Jerrod
2003-01-01
Increased demand for water in the Lake Altus drainage basin requires more accurate estimates of water use for irrigation. The U.S. Geological Survey, in cooperation with the U.S. Bureau of Reclamation, is investigating new techniques to improve water-use estimates for irrigation purposes in the Lake Altus drainage basin. Empirical estimates of reference evapotranspiration, crop evapotranspiration, and crop irrigation water requirements for nine major crops were calculated from September 1999 to October 2000 using a solar radiation-based evapotranspiration model. Estimates of irrigation water use were calculated using remotely sensed irrigated crop acres derived from Landsat 7 Enhanced Thematic Mapper Plus imagery and were compared with irrigation water-use estimates calculated from irrigated crop acres reported by the Oklahoma Water Resources Board and the Texas Water Development Board for the 2000 growing season. The techniques presented will help manage water resources in the Lake Altus drainage basin and may be transferable to other areas with similar water management needs. Irrigation water use calculated from the remotely sensed irrigated acres was estimated at 154,920 acre-feet; whereas, irrigation water use calculated from state reported irrigated crop acres was 196,026 acre-feet, a 23 percent difference. The greatest difference in irrigation water use was in Carson County, Texas. Irrigation water use for Carson County, Texas, calculated from the remotely sensed irrigated acres was 58,555 acrefeet; whereas, irrigation water use calculated from state reported irrigated acres was 138,180 acre-feet, an 81 percent difference. The second greatest difference in irrigation water use occurred in Beckham County, Oklahoma. Differences between the two irrigation water use estimates are due to the differences of irrigated crop acres derived from the mapping process and those reported by the Oklahoma Water Resources Board and Texas Water Development Board.
-
Safeguards and retrievability from waste forms
DOE Office of Scientific and Technical Information (OSTI.GOV)
Danker, W.
1996-05-01
This report describes issues discussed at a session from the PLutonium Stabilization and Immobilization Workshop related to safeguards and retrievability from waste forms. Throughout the discussion, the group probed the goals of disposition efforts, particularly an understanding of the {open_quotes}spent fuel standard{close_quotes}, since the disposition material form derives from these goals. The group felt strongly that not only the disposition goals but safeguards to meet these goals could affect the material form. Accordingly, the Department was encouraged to explore and apply safeguards as early in the implementation process as possible. It was emphasized that this was particularly true for anymore » planned use of existing facilities. It is much easier to build safeguards approaches into the development of new facilities, than to backfit existing facilities. Accordingly, special safeguards challenges are likely to be encountered, given the cost and schedule advantages offered by use of existing facilities.« less
-
7 CFR 400.408 - Safeguards and storage.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 6 2013-01-01 2013-01-01 false Safeguards and storage. 400.408 Section 400.408... and Storage of Social Security Account Numbers and Employer Identification Numbers § 400.408 Safeguards and storage. Records must be maintained in secured storage with proper safeguards sufficient to...
-
7 CFR 400.408 - Safeguards and storage.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 6 2011-01-01 2011-01-01 false Safeguards and storage. 400.408 Section 400.408... and Storage of Social Security Account Numbers and Employer Identification Numbers § 400.408 Safeguards and storage. Records must be maintained in secured storage with proper safeguards sufficient to...
-
7 CFR 400.408 - Safeguards and storage.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 6 2012-01-01 2012-01-01 false Safeguards and storage. 400.408 Section 400.408... and Storage of Social Security Account Numbers and Employer Identification Numbers § 400.408 Safeguards and storage. Records must be maintained in secured storage with proper safeguards sufficient to...
-
Code of Federal Regulations, 2011 CFR
2011-01-01
... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Safeguarding. 2500.9 Section 2500.9 Administrative Personnel OFFICE OF ADMINISTRATION, EXECUTIVE OFFICE OF THE PRESIDENT INFORMATION SECURITY REGULATION § 2500.9 Safeguarding. The Office of Administration shall protect information in its custody...
-
Code of Federal Regulations, 2010 CFR
2010-01-01
... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Safeguarding. 2500.9 Section 2500.9 Administrative Personnel OFFICE OF ADMINISTRATION, EXECUTIVE OFFICE OF THE PRESIDENT INFORMATION SECURITY REGULATION § 2500.9 Safeguarding. The Office of Administration shall protect information in its custody...
-
Visualizing Safeguards: Software for Conceptualizing and Communicating Safeguards Data
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gallucci, N.
2015-07-12
The nuclear programs of states are complex and varied, comprising a wide range of fuel cycles and facilities. Also varied are the types and terms of states’ safeguards agreements with the IAEA, each placing different limits on the inspectorate’s access to these facilities. Such nuances make it difficult to draw policy significance from the ground-level nuclear activities of states, or to attribute ground-level outcomes to the implementation of specific policies or initiatives. While acquiring a firm understanding of these relationships is critical to evaluating and formulating effective policy, doing so requires collecting and synthesizing large bodies of information. Maintaining amore » comprehensive working knowledge of the facilities comprising even a single state’s nuclear program poses a challenge, yet marrying this information with relevant safeguards and verification information is more challenging still. To facilitate this task, Brookhaven National Laboratory has developed a means of capturing the development, operation, and safeguards history of all the facilities comprising a state’s nuclear program in a single graphic. The resulting visualization offers a useful reference tool to policymakers and analysts alike, providing a chronology of states’ nuclear development and an easily digestible history of verification activities across their fuel cycles.« less
-
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Safeguards. 947.55 Section 947.55 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... safeguards to prevent shipments pursuant to § 947.54 from entering channels of trade and other outlets for...
-
TU-A-18C-01: ACR Accreditation Updates in CT, Ultrasound, Mammography and MRI
DOE Office of Scientific and Technical Information (OSTI.GOV)
Price, R; Berns, E; Hangiandreou, N
2014-06-15
A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, the ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-datemore » as the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, mammography, ultrasound, and computed tomography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program. To understand the new requirements of the ACR ultrasound accreditation program, and roles the physicist can play in annual equipment surveys and setting up and supervising the routine QC program. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process.« less
-
43 CFR 2462.1 - Publication of notice of, and public hearings on, proposed classification.
Code of Federal Regulations, 2011 CFR
2011-10-01
... hearings on, proposed classification. 2462.1 Section 2462.1 Public Lands: Interior Regulations Relating to... (2000) BUREAU INITIATED CLASSIFICATION SYSTEM Disposal Classification Procedure: Over 2,560 Acres § 2462.1 Publication of notice of, and public hearings on, proposed classification. The authorized officer...
-
Regional Cooperation to Strengthen Safeguards
DOE Office of Scientific and Technical Information (OSTI.GOV)
Minnini, Margot; Elkhamri, Oksana O.
2016-06-06
President Obama’s decision over four years ago to ”pivot” toward Asia represented an important strategic shift in American foreign policy and a rebalancing of U.S. economic and security engagement in the Asia-Pacific countries. The United States has since supported a variety of regional initiatives aimed at promoting nuclear security and safeguards. When a new regional organization, the Asia-Pacific Safeguards Network (APSN) was established in 2010, DOE/NNSA became an early member and enthusiastic advocate. Launched on the initiative of Australia, Japan, Republic of Korea, and Indonesia, the APSN aims to strengthen the quality and effectiveness of safeguards implementation in the Asia-Pacificmore » region.« less
-
Updated hazard rate equations for dual safeguard systems.
Rothschild, Marc
2007-04-11
A previous paper by this author [M.J. Rothschild, Updated hazard rate equation for single safeguards, J. Hazard. Mater. 130 (1-2) (2006) 15-20] showed that commonly used analytical methods for quantifying failure rates overestimates the risk in some circumstances. This can lead the analyst to mistakenly believe that a given operation presents an unacceptable risk. For a single safeguard system, a formula was presented in that paper that accurately evaluates the risk over a wide range of conditions. This paper expands on that analysis by evaluating the failure rate for dual safeguard systems. The safeguards can be activated at the same time or at staggered times, and the safeguard may provide an indication whether it was successful upon a challenge, or its status may go undetected. These combinations were evaluated using a Monte Carlo simulation. Empirical formulas for evaluating the hazard rate were developed from this analysis. It is shown that having the safeguards activate at the same time while providing positive feedback of their individual actions is the most effective arrangement in reducing the hazard rate. The hazard rate can also be reduced by staggering the testing schedules of the safeguards.
-
Strengthening IAEA Safeguards for Research Reactors
DOE Office of Scientific and Technical Information (OSTI.GOV)
Reid, Bruce D.; Anzelon, George A.; Budlong-Sylvester, Kory
During their December 10-11, 2013, workshop in Grenoble France, which focused on the history and future of safeguarding research reactors, the United States, France and the United Kingdom (UK) agreed to conduct a joint study exploring ways to strengthen the IAEA’s safeguards approach for declared research reactors. This decision was prompted by concerns about: 1) historical cases of non-compliance involving misuse (including the use of non-nuclear materials for production of neutron generators for weapons) and diversion that were discovered, in many cases, long after the violations took place and as part of broader pattern of undeclared activities in half amore » dozen countries; 2) the fact that, under the Safeguards Criteria, the IAEA inspects some reactors (e.g., those with power levels under 25 MWt) less than once per year; 3) the long-standing precedent of States using heavy water research reactors (HWRR) to produce plutonium for weapons programs; 4) the use of HEU fuel in some research reactors; and 5) various technical characteristics common to some types of research reactors that could provide an opportunity for potential proliferators to misuse the facility or divert material with low probability of detection by the IAEA. In some research reactors it is difficult to detect diversion or undeclared irradiation. In addition, infrastructure associated with research reactors could pose a safeguards challenge. To strengthen the effectiveness of safeguards at the State level, this paper advocates that the IAEA consider ways to focus additional attention and broaden its safeguards toolbox for research reactors. This increase in focus on the research reactors could begin with the recognition that the research reactor (of any size) could be a common path element on a large number of technically plausible pathways that must be considered when performing acquisition pathway analysis (APA) for developing a State Level Approach (SLA) and Annual Implementation Plan
-
7 CFR 760.632 - Payment acres.
Code of Federal Regulations, 2010 CFR
2010-01-01
... acreage of a crop produced on land that is not eligible for crop insurance or NAP. (h) For any crop acreage for which crop insurance or NAP coverage is canceled, those acres will no longer be considered the...
-
LANL Safeguards and Security Assurance Program. Revision 6
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1995-04-03
The Safeguards and Security (S and S) Assurance Program provides a continuous quality improvement approach to ensure effective, compliant S and S program implementation throughout the Los Alamos National Laboratory. Any issues identified through the various internal and external assessments are documented, tracked and closed using the Safeguards and Security Issue Management Program. The Laboratory utilizes an integrated S and S systems approach to protect US Department of Energy (DOE) interests from theft or diversion of special nuclear material (SNM), sabotage, espionage, loss or theft of classified/controlled matter or government property, and other hostile acts that may cause unacceptable impactsmore » on national security, health and safety of employees and the public, and the environment. This document explains the basis, scope, and conduct of the S and S process to include: self-assessments, issue management, risk assessment, and root cause analysis. It also provides a discussion of S and S topical areas, roles and responsibilities, process flow charts, minimum requirements, methodology, terms, and forms.« less
-
10 CFR 75.7 - Notification of IAEA safeguards.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 2 2011-01-01 2011-01-01 false Notification of IAEA safeguards. 75.7 Section 75.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) SAFEGUARDS ON NUCLEAR MATERIAL-IMPLEMENTATION OF US/IAEA AGREEMENT General Provisions § 75.7 Notification of IAEA safeguards. (a) The licensee must inform the NRC...
-
10 CFR 75.7 - Notification of IAEA safeguards.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 2 2010-01-01 2010-01-01 false Notification of IAEA safeguards. 75.7 Section 75.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) SAFEGUARDS ON NUCLEAR MATERIAL-IMPLEMENTATION OF US/IAEA AGREEMENT General Provisions § 75.7 Notification of IAEA safeguards. (a) The licensee must inform the NRC...
-
32 CFR 154.68 - Safeguarding procedures.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 1 2012-07-01 2012-07-01 false Safeguarding procedures. 154.68 Section 154.68 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE SECURITY DEPARTMENT OF DEFENSE... Safeguarding procedures. Personnel security investigative reports and personnel security determination...
-
Training to raise staff awareness about safeguarding children.
Fleming, Jane
2015-04-01
To improve outcomes for children and young people health organisations are required to train all staff in children's safeguarding. This creates difficulties for large complex organisations where most staff provide services to the adult population. Heart of England NHS Foundation Trust is a large acute and community trust that had difficulties in engaging staff in children's safeguarding training. Compliance rates for clinical staff who were trained in children's safeguarding were low and needed to be addressed. This article sets out why safeguarding training is important for all staff and how the trust achieved staff engagement and improved compliance rates. To evaluate, maintain and develop safeguarding knowledge, understanding, skills, attitude and behaviour further resources are planned to allow access to learning resources in a variety of formats.
-
The evolution of information-driven safeguards
DOE Office of Scientific and Technical Information (OSTI.GOV)
Budlong-sylvester, Kory W; Pilat, Joseph F
2010-10-14
From the adoption of the Model Additional Protocol and integrated safeguards in the 1990s, to current International Atomic Energy Agency (IAEA) efforts to deal with cases of noncompliance, the question of how the Agency can best utilize all the information available to it remains of great interest and increasing importance. How might the concept of 'information-driven' safeguards (IDS) evolve in the future? The ability of the Agency to identify and resolve anomalies has always been important and has emerged as a core Agency function in recent years as the IAEA has had to deal with noncompliance in Iran and themore » Democratic People's Republic of Korea (DPRK). Future IAEA safeguards implementation should be designed with the goal of facilitating and enhancing this vital capability. In addition, the Agency should utilize all the information it possesses, including its in-house assessments and expertise, to direct its safeguards activities. At the State level, knowledge of proliferation possibilities is currently being used to guide the analytical activities of the Agency and to develop inspection plans. How far can this approach be extended? Does it apply across State boundaries? Should it dictate a larger fraction of safeguards activities? Future developments in IDS should utilize the knowledge resident within the Agency to ensure that safeguards resources flow to where they are most needed in order to address anomalies first and foremost, but also to provide greater confidence in conclusions regarding the absence of undeclared nuclear activities. The elements of such a system and related implementation issues are assessed in this paper.« less
-
Perrot, Serge; Peixoto, Mariana; Dieudé, Philippe; Hachulla, Eric; Avouac, Jerome; Ottaviani, Sebastien; Allanore, Yannick
2017-01-01
Fibromyalgia (FM) may occur with rheumatoid arthritis (RA) and systemic sclerosis (SSc), and debate remains about its diagnosis. We aimed to use three FM tools (a screening tool (FiRST), diagnostic criteria (ACR 1990 and revised 2010), to compare FM prevalence between RA and SSc patients, to describe the phenotypes of patients with comorbid FM, and to analyze links between FM and secondary Sjögren's syndrome (SS). Consecutive adult patients with confirmed RA or SSc from four university hospitals were tested with the three FM tools. FiRST detected FM in 22.6% of the 172 RA patients, with confirmation in 22.1% (ACR1990) and 19.1% (ACR2010). ACR1990FM+ RA patients had more diffuse pain, whereas ACR2010FM+ RA patients had higher BMI and pain intensity, more diffuse pain, active disease, disability, and associated SS. FiRST detected FM in 27.8% of the 122 SSc patients, with confirmation in 30.3% (ACR1990) and 23.7% (ACR2010). ACR1990FM+ SSc patients had greater disability and pain intensity, and more diffuse pain, whereas ACR2010FM+ SSc patients had higher BMI, pain intensity, more disability and diffuse pain, and associated SS. Correlations between FM diagnostic and screening tool results were modest in both conditions. Secondary SS was associated with comorbid FM. The prevalence of FM is high in SSc and RA, whatever the FM diagnostic tool used. Secondary SS is associated with FM in both RA and SSc. The revised ACR 2010 FM criteria and FiRST screening tool reveal specific phenotypes potentially useful for improving disease management.
-
78 FR 52561 - Public Land Order No. 7820; Partial Modification, Public Water Reserve No. 107; Utah
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-23
...-52455] Public Land Order No. 7820; Partial Modification, Public Water Reserve No. 107; Utah AGENCY: Bureau of Land Management, Interior. ACTION: Public Land Order. SUMMARY: This order partially modifies a withdrawal created by an Executive Order insofar as it affects 264.21 acres of public lands withdrawn from...
-
Jordan, Suzana; Maurer, Britta; Toniolo, Martin; Michel, Beat; Distler, Oliver
2015-08-01
The preliminary classification criteria for SSc lack sensitivity for mild/early SSc patients, therefore, the new ACR/EULAR classification criteria for SSc were developed. The objective of this study was to evaluate the performance of the new classification criteria for SSc in clinical practice in a cohort of mild/early patients. Consecutive patients with a clinical diagnosis of SSc, based on expert opinion, were prospectively recruited and assessed according to the EULAR Scleroderma Trials and Research group (EUSTAR) and very early diagnosis of SSc (VEDOSS) recommendations. In some patients, missing values were retrieved retrospectively from the patient's records. Patients were grouped into established SSc (fulfilling the old ACR criteria) and mild/early SSc (not fulfilling the old ACR criteria). The new ACR/EULAR criteria were applied to all patients. Of the 304 patients available for the final analysis, 162/304 (53.3%) had established SSc and 142/304 (46.7%) had mild/early SSc. All 162 established SSc patients fulfilled the new ACR/EULAR classification criteria. The remaining 142 patients had mild/early SSc. Eighty of these 142 patients (56.3%) fulfilled the new ACR/EULAR classification criteria. Patients with mild/early SSc not fulfilling the new classification criteria were most often suffering from RP, had SSc-characteristic autoantibodies and had an SSc pattern on nailfold capillaroscopy. Taken together, the sensitivity of the new ACR/EULAR classification criteria for the overall cohort was 242/304 (79.6%) compared with 162/304 (53.3%) for the ACR criteria. In this cohort with a focus on mild/early SSc, the new ACR/EULAR classification criteria showed higher sensitivity and classified more patients as definite SSc patients than the ACR criteria. © The Author 2015. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
-
Safeguards Workforce Repatriation, Retention and Utilization
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gallucci, Nicholas; Poe, Sarah
Brookhaven National Laboratory was tasked by NA-241 to assess the transition of former IAEA employees back to the United States, investigating the rate of retention and overall smoothness of the repatriation process among returning safeguards professionals. Upon conducting several phone interviews, study authors found that the repatriation process went smoothly for the vast majority and that workforce retention was high. However, several respondents expressed irritation over the minimal extent to which their safeguards expertise had been leveraged in their current positions. This sentiment was pervasive enough to prompt a follow-on study focusing on questions relating to the utilization rather thanmore » the retention of safeguards professionals. A second, web-based survey was conducted, soliciting responses from a larger sample pool. Results suggest that the safeguards workforce may be oversaturated, and that young professionals returning to the United States from Agency positions may soon encounter difficulties finding jobs in the field.« less
-
Update of the ACR-NEMA digital imaging and communications in medicine standard
NASA Astrophysics Data System (ADS)
Best, David E.; Horii, Steven C.; Bennett, William C.; Parisot, Charles R.
1992-07-01
The American College of Radiology and the National Electrical Manufacturers Association published the ACR-NEMA Digital Imaging and Communications Standard in 1985. Implementations are just now becoming available. Working groups of the committee have been very active. An expanded version of the Standard was published in 1988 and in a third version, to be known as Digital Imaging and Communications in Medicine (DICOM), is being prepared for publication in 1992. This paper briefly reviews the history of the Standard, describes the participation of the committee in international radiological imaging standards activities, and outlines the extensions planned for the DICOM Standard.
-
Wang, Beibei; Weng, Jingwei; Fan, Kangnian; Wang, Wenning
2012-03-15
The membrane fusion protein (MFP) AcrA is proposed to link the inner membrane transporter AcrB and outer membrane protein TolC, forming the tripartite AcrAB-TolC efflux pump, and was shown to be functionally indispensible. Structural and EPR studies showed that AcrA has high conformational flexibility and exhibited pH-induced conformational change. In this study, we built the complete structure of AcrA through homology modeling and performed atomistic simulations of AcrA at different pH values. It was shown that the conformational flexibility of AcrA originates from the motions of α-hairpin and MP domains. The conformational dynamics of AcrA is sensitive to specific point mutations and pH values. In agreement with the EPR experiments, the interdomain motions were restrained upon lowering pH from 7.0 to 5.0 in the simulations. It was found that the protonation/deprotonation of His285 underlies the pH-regulated conformational dynamics of AcrA by disturbing the local hydrogen bond interactions, suggesting that the changes of pH in the periplasm accompanying the drug efflux could act as a signal to trigger the action of AcrA, which undergoes reversible conformational rearrangement. © 2012 American Chemical Society
-
Sagebrush Rebellion. [Proposed transfer of 175 million acres of Federal lands to states
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shay, R.
1980-01-01
The Sagebrush Rebellion concerns a proposal to transfer 175 million acres of Federally-owned wildlands to state governments, an idea with political appeal for many an opportunity to replace decades of conservation and wilderness planning with development and speculation. The project is seen as a way to grab public lands for private profit, its supporters largely drawn from the group which will gain either financially or politically. The movement grew out of government efforts to cut back on overgrazing on public lands and alert the public to the environmental impacts of grazing policies. Although legislative efforts have not succeeded, the movementmore » has hindered the Bureau of Land Management and has championed private interests to the point where use violations and efforts to discredit government management are flagrant. A concerted lobbying effort is called for to prevent a massive land transfer. (DCK)« less
-
16 CFR 314.3 - Standards for safeguarding customer information.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Standards for safeguarding customer... OF CONGRESS STANDARDS FOR SAFEGUARDING CUSTOMER INFORMATION § 314.3 Standards for safeguarding customer information. (a) Information security program. You shall develop, implement, and maintain a...
-
Kim, Hong-Man; Xu, Yongbin; Lee, Minho; Piao, Shunfu; Sim, Se-Hoon; Ha, Nam-Chul; Lee, Kangseok
2010-01-01
Tripartite efflux pumps found in Gram-negative bacteria are involved in antibiotic resistance and toxic-protein secretion. In this study, we show, using site-directed mutational analyses, that the conserved residues located in the tip region of the α-hairpin of the membrane fusion protein (MFP) AcrA play an essential role in the action of the tripartite efflux pump AcrAB-TolC. In addition, we provide in vivo functional data showing that both the length and the amino acid sequence of the α-hairpin of AcrA can be flexible for the formation of a functional AcrAB-TolC pump. Genetic-complementation experiments further indicated functional interrelationships between the AcrA hairpin tip region and the TolC aperture tip region. Our findings may offer a molecular basis for understanding the multidrug resistance of pathogenic bacteria. PMID:20581201
-
34 CFR 300.150 - SEA implementation of procedural safeguards.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 34 Education 2 2012-07-01 2012-07-01 false SEA implementation of procedural safeguards. 300.150... EDUCATION OF CHILDREN WITH DISABILITIES State Eligibility Sea Responsibility for General Supervision and Implementation of Procedural Safeguards § 300.150 SEA implementation of procedural safeguards. The SEA (and any...
-
34 CFR 300.150 - SEA implementation of procedural safeguards.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 34 Education 2 2013-07-01 2013-07-01 false SEA implementation of procedural safeguards. 300.150... EDUCATION OF CHILDREN WITH DISABILITIES State Eligibility Sea Responsibility for General Supervision and Implementation of Procedural Safeguards § 300.150 SEA implementation of procedural safeguards. The SEA (and any...
-
34 CFR 300.150 - SEA implementation of procedural safeguards.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 34 Education 2 2014-07-01 2013-07-01 true SEA implementation of procedural safeguards. 300.150... EDUCATION OF CHILDREN WITH DISABILITIES State Eligibility Sea Responsibility for General Supervision and Implementation of Procedural Safeguards § 300.150 SEA implementation of procedural safeguards. The SEA (and any...
-
34 CFR 300.150 - SEA implementation of procedural safeguards.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 34 Education 2 2011-07-01 2010-07-01 true SEA implementation of procedural safeguards. 300.150... EDUCATION OF CHILDREN WITH DISABILITIES State Eligibility Sea Responsibility for General Supervision and Implementation of Procedural Safeguards § 300.150 SEA implementation of procedural safeguards. The SEA (and any...
-
34 CFR 300.150 - SEA implementation of procedural safeguards.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 34 Education 2 2010-07-01 2010-07-01 false SEA implementation of procedural safeguards. 300.150... EDUCATION OF CHILDREN WITH DISABILITIES State Eligibility Sea Responsibility for General Supervision and Implementation of Procedural Safeguards § 300.150 SEA implementation of procedural safeguards. The SEA (and any...
-
Safeguards: The past present, and future
DOE Office of Scientific and Technical Information (OSTI.GOV)
Seaton, M.B.
1987-07-01
The non-destructive assay techniques developed at Los Alamos have become a primary means for verification by the IAEA and most important for domestic safeguards. We must challenge our assumptions, e.g., that inventory differences are a valid measure of safeguards performance, that more money is the solution, and the threats are much exaggerated. A human reliability program will be initiated. Material control, accounting, and physical protection need further integration. A serious effort involving scholarships, internships, etc. is needed to attract and motivate young people. Increased emphasis will be placed on designing safeguards into new systems such as laser isotope separation. Finally,more » continuing generous support for the IAEA is most important.« less
-
10 CFR Appendix G to Part 73 - Reportable Safeguards Events
Code of Federal Regulations, 2010 CFR
2010-01-01
... vulnerability in a safeguard system that could allow unauthorized or undetected access to a protected area... the safeguards event log. (a) Any failure, degradation, or discovered vulnerability in a safeguards...
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Beyer, Brian David; Beddingfield, David H; Durst, Philip
2010-01-01
The design of the Pebble Bed Modular Reactor (PBMR) does not fit or seem appropriate to the IAEA safeguards approach under the categories of light water reactor (LWR), on-load refueled reactor (OLR, i.e. CANDU), or Other (prismatic HTGR) because the fuel is in a bulk form, rather than discrete items. Because the nuclear fuel is a collection of nuclear material inserted in tennis-ball sized spheres containing structural and moderating material and a PBMR core will contain a bulk load on the order of 500,000 spheres, it could be classified as a 'Bulk-Fuel Reactor.' Hence, the IAEA should develop unique safeguardsmore » criteria. In a multi-lab DOE study, it was found that an optimized blend of: (i) developing techniques to verify the plutonium content in spent fuel pebbles, (ii) improving burn-up computer codes for PBMR spent fuel to provide better understanding of the core and spent fuel makeup, and (iii) utilizing bulk verification techniques for PBMR spent fuel storage bins should be combined with the historic IAEA and South African approaches of containment and surveillance to verify and maintain continuity of knowledge of PBMR fuel. For all of these techniques to work the design of the reactor will need to accommodate safeguards and material accountancy measures to a far greater extent than has thus far been the case. The implementation of Safeguards-by-Design as the PBMR design progresses provides an approach to meets these safeguards and accountancy needs.« less
-
The radiology job market: analysis of the ACR jobs board.
Prabhakar, Anand M; Oklu, Rahmi; Harvey, H Benjamin; Harisinghani, Mukesh G; Rosman, David A
2014-05-01
The aim of this study was to assess the status of the radiology job market as represented by the ACR Jobs Board from October 2010 to June 2013. With the assistance of the ACR, data from the ACR Jobs Board from October 2010 through June 2013, including the numbers of monthly new job seekers, new job postings, and job posting clicks, were gathered and used to calculate a monthly competitive index, defined as the ratio of new job seekers to new job postings. During the study period, the mean number of new job seekers was 168 per month, which was significantly greater than the 84 average new job postings for any given month (P = .0002). There was no significant difference between 2011 and 2012 with regard to the number of new job seekers or job postings. Over the time period assessed, more new job seekers registered in October and November 2010, August to November 2011, and October and November 2012. These periods were also associated with the highest competitive index values. There were less job seekers in the winter and spring of 2011, 2012, and 2013, periods associated with lower competitive index values. ACR Jobs Board activity, measured by job posting clicks, was significantly higher in 2012 than in 2011 (P < .004). On the basis of the ACR Jobs Board, there were consistently more new job seekers than job postings throughout the study period, and fall is the period in the year most associated with the highest competitive index for radiologist employment. Copyright © 2014 American College of Radiology. Published by Elsevier Inc. All rights reserved.
-
University of Texas Safeguards by Design Problem Statement
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rauch, Eric Benton; Scherer, Carolynn P.; Ruggiero, Christy E.
This document describes the problem statement that students at the University of Texas will use for their senior level capstone design class. The purpose of this project is to introduce students to Safeguards by Design concepts as part of their capstone design course at the culmination of their degree program. This work is supported by Los Alamos National Laboratory with FY17 and FY18 programmatic funding from the U. S. Department of Energy’s (DOE) National Nuclear Security Administration (NNSA), through the Office of Defense Nuclear Nonproliferation (DNN), Office of International Nuclear Safeguards (INS), Next Generation Safeguards Initiative (NGSI), Human Resource Developmentmore » Program, Safeguards by Design Project.« less
-
Ip, Hermia; Stratton, Kelly; Zgurskaya, Helen; Liu, Jun
2003-12-12
The multidrug efflux system AcrA-AcrB-TolC of Escherichia coli expels a wide range of drugs directly into the external medium from the bacterial cell. The mechanism of the efflux process is not fully understood. Of an elongated shape, AcrA is thought to span the periplasmic space coordinating the concerted operation of the inner and outer membrane proteins AcrB and TolC. In this study, we used site-directed spin labeling (SDSL) EPR (electron paramagnetic resonance) spectroscopy to investigate the molecular conformations of AcrA in solution. Ten AcrA mutants, each with an alanine to cysteine substitution, were engineered, purified, and labeled with a nitroxide spin label. EPR analysis of spin-labeled AcrA variants indicates that the side chain mobilities are consistent with the predicted secondary structure of AcrA. We further demonstrated that acidic pH induces oligomerization and conformational change of AcrA, and that the structural changes are reversible. These results suggest that the mechanism of action of AcrA in drug efflux is similar to the viral membrane fusion proteins, and that AcrA actively mediates the efflux of substrates.
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-05
...] Public Land Order No. 7790; Withdrawal of Public Lands for the Parting of the Ways National Historic Site; Wyoming AGENCY: Bureau of Land Management, Interior. ACTION: Public land order. SUMMARY: This order withdraws 40 acres of public land from settlement, sale, location, and entry under the general land laws...
-
USSP-IAEA WORKSHOP ON ADVANCED SENSORS FOR SAFEGUARDS.
DOE Office of Scientific and Technical Information (OSTI.GOV)
PEPPER,S.; QUEIROLO, A.; ZENDEL, M.
2007-11-13
The IAEA Medium Term Strategy (2006-2011) defines a number of specific goals in respect to the IAEA's ability to provide assurances to the international community regarding the peaceful use of nuclear energy through States adherences to their respective non-proliferation treaty commitments. The IAEA has long used and still needs the best possible sensors to detect and measure nuclear material. The Department of Safeguards, recognizing the importance of safeguards-oriented R&D, especially targeting improved detection capabilities for undeclared facilities, materials and activities, initiated a number of activities in early 2005. The initiatives included letters to Member State Support Programs (MSSPs), personal contactsmore » with known technology holders, topical meetings, consultant reviews of safeguards technology, and special workshops to identify new and novel technologies and methodologies. In support of this objective, the United States Support Program to IAEA Safeguards hosted a workshop on ''Advanced Sensors for Safeguards'' in Santa Fe, New Mexico, from April 23-27, 2007. The Organizational Analysis Corporation, a U.S.-based management consulting firm, organized and facilitated the workshop. The workshop's goal was to help the IAEA identify and plan for new sensors for safeguards implementation. The workshop, which was attended by representatives of seven member states and international organizations, included presentations by technology holders and developers on new technologies thought to have relevance to international safeguards, but not yet in use by the IAEA. The presentations were followed by facilitated breakout sessions where the participants considered two scenarios typical of what IAEA inspectors might face in the field. One scenario focused on an enrichment plant; the other scenario focused on a research reactor. The participants brainstormed using the technologies presented by the participants and other technologies known to them to propose
-
Effectiveness of urban stormwater control measures in a 100-acre test site
Kansas City, Missouri chose a test area (100 acres) and a control area (80 acres) to test the effectiveness of urban stormwater control (SCM) deployment in conjunction with the USEPA, University of Alabama, University of Missouri-Kansas City and TetraTech. Both the test and cont...
-
Modeling and Simulation for Safeguards and Nonproliferation Workshop
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gilligan, Kimberly V.; Kirk, Bernadette Lugue
2015-01-01
The Modeling and Simulation for Safeguards and Nonproliferation Workshop was held December 15–18, 2014, at Oak Ridge National Laboratory. This workshop was made possible by the Next Generation Safeguards Initiative Human Capital Development (NGSI HCD) Program. The idea of the workshop was to move beyond the tried-and-true boot camp training of nonproliferation concepts to spend several days on the unique perspective of applying modeling and simulation (M&S) solutions to safeguards challenges.
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-19
... textile and apparel safeguard provision, provided for in Article 4.1 of the United States-Korea Free Trade... elimination of a customs duty under the Agreement, a Korean textile or apparel article is being imported into... for that article, and under such conditions as to cause serious damage or actual threat thereof to a U...
-
32 CFR 635.2 - Safeguarding official information.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 4 2010-07-01 2010-07-01 true Safeguarding official information. 635.2 Section 635.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS LAW ENFORCEMENT REPORTING Records Administration § 635.2 Safeguarding official information. (a) Military police...
-
7 CFR 352.10 - Inspection; safeguards; disposal.
Code of Federal Regulations, 2010 CFR
2010-01-01
... facilities for immediate exportation. (x) Any other related factor which should be considered, such as intent...; safeguards; disposal. (a) Inspection and release. Prohibited and restricted products and articles subject to... restricted products and articles under this part shall be subject to such safeguards as may be prescribed in...
-
ACEHSA accreditation safeguards the public interest.
Sundre, Steven M
2004-01-01
Daily, we are reminded that the public's investment in attaining quality health and medical care is among the most important priorities of our nation's citizens. Central to realizing that attainment is the level of professional competence of those charged with managing the nation's health resources. The not-for-profit Accrediting Commission on Education for Health Services Administration is the sole national organization governing the standards by which future health managers, administrators, and executives are educated and trained in accredited graduate programs. The impact of the ACEHSA is growing as health and medical leaders, government and regulatory policy-makers, insurance executives, special interest groups, and, of course, members of the public increasingly realize that top-flight healthcare delivery requires excellence in the management of health resources.
-
Wahlgren, Lina; Schantz, Peter
2011-01-17
Route environments can positively influence people's active commuting and thereby contribute to public health. The Active Commuting Route Environment Scale (ACRES) was developed to study active commuters' perceptions of their route environments. However, bicycle commuters represent a small portion of the population in many cities and thus are difficult to study using population-based material. Therefore, the aim of this study is to expand the state of knowledge concerning the criterion-related validity of the ACRES and the representativity using an advertisement-recruited sample. Furthermore, by comparing commuting route environment profiles of inner urban and suburban areas, we provide a novel basis for understanding the relationship between environment and bikeability. Bicycle commuters from Greater Stockholm, Sweden, advertisement- (n = 1379) and street-recruited (n = 93), responded to the ACRES. Traffic planning and environmental experts from the Municipality of Stockholm (n = 24) responded to a modified version of the ACRES. The criterion-related validity assessments were based on whether or not differences between the inner urban and the suburban route environments, as indicated by the experts and by four existing objective measurements, were reflected by differences in perceptions of these environments. Comparisons of ratings between advertisement- and street-recruited participants were used for the assessments of representativity. Finally, ratings of inner urban and suburban route environments were used to evaluate commuting route environment profiles. Differences in ratings of the inner urban and suburban route environments by the advertisement-recruited participants were in accord with the existing objective measurements and corresponded reasonably well with those of the experts. Overall, there was a reasonably good correspondence between the advertisement- and street-recruited participants' ratings. Distinct differences in commuting route environment
-
2011-01-01
Background Route environments can positively influence people's active commuting and thereby contribute to public health. The Active Commuting Route Environment Scale (ACRES) was developed to study active commuters' perceptions of their route environments. However, bicycle commuters represent a small portion of the population in many cities and thus are difficult to study using population-based material. Therefore, the aim of this study is to expand the state of knowledge concerning the criterion-related validity of the ACRES and the representativity using an advertisement-recruited sample. Furthermore, by comparing commuting route environment profiles of inner urban and suburban areas, we provide a novel basis for understanding the relationship between environment and bikeability. Methods Bicycle commuters from Greater Stockholm, Sweden, advertisement- (n = 1379) and street-recruited (n = 93), responded to the ACRES. Traffic planning and environmental experts from the Municipality of Stockholm (n = 24) responded to a modified version of the ACRES. The criterion-related validity assessments were based on whether or not differences between the inner urban and the suburban route environments, as indicated by the experts and by four existing objective measurements, were reflected by differences in perceptions of these environments. Comparisons of ratings between advertisement- and street-recruited participants were used for the assessments of representativity. Finally, ratings of inner urban and suburban route environments were used to evaluate commuting route environment profiles. Results Differences in ratings of the inner urban and suburban route environments by the advertisement-recruited participants were in accord with the existing objective measurements and corresponded reasonably well with those of the experts. Overall, there was a reasonably good correspondence between the advertisement- and street-recruited participants' ratings. Distinct differences in
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dreicer, M; Anzelon, G; Essner, J
2008-10-17
Key component of the Next Generation Safeguards Initiative (NGSI) launched by the National Nuclear Security Administration is the development of human capital to meet present and future challenges to the safeguards regime. An effective university-level education in safeguards and related disciplines is an essential element in a layered strategy to rebuild the safeguards human resource capacity. Two pilot programs at university level, involving 44 students, were initiated and implemented in spring-summer 2008 and linked to hands-on internships at LANL or LLNL. During the internships, students worked on specific safeguards-related projects with a designated Laboratory Mentor to provide broader exposure tomore » nuclear materials management and information analytical techniques. The Safeguards and Nuclear Material Management pilot program was a collaboration between the Texas A&M University (TAMU), Los Alamos National Laboratory (LANL) and Lawrence Livermore National Laboratory (LLNL). It included a 16-lecture course held during a summer internship program. The instructors for the course were from LANL together with TAMU faculty and LLNL experts. The LANL-based course was shared with the students spending their internship at LLNL via video conference. A week-long table-top (or hands-on) exercise on was also conducted at LANL. The student population was a mix of 28 students from a 12 universities participating in a variety of summer internship programs held at LANL and LLNL. A large portion of the students were TAMU students participating in the NGSI pilot. The International Nuclear Safeguards Policy and Information Analysis pilot program was implemented at the Monterey Institute for International Studies (MIIS) in cooperation with LLNL. It included a two-week intensive course consisting of 20 lectures and two exercises. MIIS, LLNL, and speakers from other U.S. national laboratories (LANL, BNL) delivered lectures for the audience of 16 students. The majority of
-
Reactor safeguards system assessment and design. Volume I
DOE Office of Scientific and Technical Information (OSTI.GOV)
Varnado, G.B.; Ericson, D.M. Jr.; Daniel, S.L.
1978-06-01
This report describes the development and application of a methodology for evaluating the effectiveness of nuclear power reactor safeguards systems. Analytic techniques are used to identify the sabotage acts which could lead to release of radioactive material from a nuclear power plant, to determine the areas of a plant which must be protected to assure that significant release does not occur, to model the physical plant layout, and to evaluate the effectiveness of various safeguards systems. The methodology was used to identify those aspects of reactor safeguards systems which have the greatest effect on overall system performance and which, therefore,more » should be emphasized in the licensing process. With further refinements, the methodology can be used by the licensing reviewer to aid in assessing proposed or existing safeguards systems.« less
-
30 CFR 77.1013 - Air drills; safeguards.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Air drills; safeguards. 77.1013 Section 77.1013... Control § 77.1013 Air drills; safeguards. Air shall be turned off and bled from the air hoses before hand-held air drills are moved from one working area to another. ...
-
30 CFR 77.1013 - Air drills; safeguards.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Air drills; safeguards. 77.1013 Section 77.1013... Control § 77.1013 Air drills; safeguards. Air shall be turned off and bled from the air hoses before hand-held air drills are moved from one working area to another. ...
-
30 CFR 77.1013 - Air drills; safeguards.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Air drills; safeguards. 77.1013 Section 77.1013... Control § 77.1013 Air drills; safeguards. Air shall be turned off and bled from the air hoses before hand-held air drills are moved from one working area to another. ...
-
30 CFR 77.1013 - Air drills; safeguards.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Air drills; safeguards. 77.1013 Section 77.1013... Control § 77.1013 Air drills; safeguards. Air shall be turned off and bled from the air hoses before hand-held air drills are moved from one working area to another. ...
-
30 CFR 77.1013 - Air drills; safeguards.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Air drills; safeguards. 77.1013 Section 77.1013... Control § 77.1013 Air drills; safeguards. Air shall be turned off and bled from the air hoses before hand-held air drills are moved from one working area to another. ...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-28
...] Public Land Order No. 7773; Emergency Withdrawal of Public and National Forest System Lands, Coconino and... Forest System lands from location and entry under the 1872 Mining Law for a period of 6 months under the... described above aggregate approximately 1,010,776 acres public and National Forest System lands in Coconino...
-
Savoy/TMA Public Education Campus Plan
ERIC Educational Resources Information Center
21st Century School Fund, 2006
2006-01-01
The Savoy/TMA Public Education Campus encompasses the 3.5 acres that includes the Savoy Elementary School and the former Nichols Avenue School, now the fully modernized Thurgood Marshall Academy Public Charter High School (TMA) and a recreation center sponsored by the Department of Parks and Recreation. As a part of public initiatives to better…
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-18
... in Title III, Subtitle B, Section 321 through Section 328 of the United States-Peru Trade Promotion.... Background Title III, Subtitle B, Section 321 through Section 328 of the United States-Peru Trade Promotion... Promotion Agreement Implementation Act, the Committee has determined that actions taken under this safeguard...
-
Safeguardability of the vitrification option for disposal of plutonium
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pillay, K.K.S.
1996-05-01
Safeguardability of the vitrification option for plutonium disposition is rather complex and there is no experience base in either domestic or international safeguards for this approach. In the present treaty regime between the US and the states of the former Soviet Union, bilaterial verifications are considered more likely with potential for a third-party verification of safeguards. There are serious technological limitations to applying conventional bulk handling facility safeguards techniques to achieve independent verification of plutonium in borosilicate glass. If vitrification is the final disposition option chosen, maintaining continuity of knowledge of plutonium in glass matrices, especially those containing boron andmore » those spike with high-level wastes or {sup 137}Cs, is beyond the capability of present-day safeguards technologies and nondestructive assay techniques. The alternative to quantitative measurement of fissile content is to maintain continuity of knowledge through a combination of containment and surveillance, which is not the international norm for bulk handling facilities.« less
-
NASA Astrophysics Data System (ADS)
Podimata, M. V.; Bekri, E. S.; Yannopoulos, P. C.
2012-04-01
Framework Directive (WFD) 2000/60, but a practical necessity for the safeguarding of public health and ecosystem health, in general. The present study aims at developing a simple methodology for assessing spatial distribution characteristics of pollution in Erymanthos catchment. Pollution loads at various sites in Erymanthos watershed were illustrated with Geographical Information System (GIS). Flow rates of Erymanthos River were also taken into consideration. Based on previous studies, in situ river discharges have been compared to simulated discharges in order to calibrate the rainfall-runoff model ENNS which can then predict future scenarios regarding the river flow rates with consideration of climate change effects. The goal of this study is to detect the pertinent points and suggest a) suitable buffer zones in areas with high pollution risk and b) simple technical works in order to prevent the main channel of Erymanthos River from direct polluting discharges. The above systems could also act supportively in groundwater enrichment, forest protection and soil erosion prevention. Authors believe that the results of the study could assist authorities and engineers to design and develop strategies of improving river water quality and safeguarding public health. The proposed measures may be applicable to other catchments as well.
-
The 2017 ACR Workforce Survey: Management Trends and Strategic Needs.
Harolds, Jay A; Bluth, Edward I
2018-03-01
The 2017 ACR Workforce Survey included questions for group leaders about management trends and areas in which they need more help from the ACR. Respondents identified point of care ultrasound as the area in which they need the most help. Most respondents gave positive or neutral answers regarding their role in the management of radiology allied health professionals and radiology information technology, and most believed their role and influence in decision making in the organization were not decreasing. Copyright © 2017 American College of Radiology. Published by Elsevier Inc. All rights reserved.
-
5 CFR 293.106 - Safeguarding information about individuals.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Safeguarding information about individuals. 293.106 Section 293.106 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Basic Policies on Maintenance of Personnel Records § 293.106 Safeguarding...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-18
... 35138] Public Land Order No. 7787; Withdrawal of Public and National Forest System Lands in the Grand...: This order withdraws approximately 1,006,545 acres of public and National Forest System lands from... National Forest, 800 South 6th Street, Williams, Arizona 86046, (928) 635-8367. Persons who use a...
-
43 CFR 2462.2 - Publication of notice of classification.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Publication of notice of classification... CLASSIFICATION SYSTEM Disposal Classification Procedure: Over 2,560 Acres § 2462.2 Publication of notice of classification. After having considered the comments received as the result of publication, the authorized...
-
International Safeguards and the Pacific Northwest National Laboratory
DOE Office of Scientific and Technical Information (OSTI.GOV)
Olsen, Khris B.; Smith, Leon E.; Frazar, Sarah L.
Established in 1965, Pacific Northwest National Laboratory’s (PNNL) strong technical ties and shared heritage with the nearby U.S. Department of Energy Hanford Site were central to the early development of expertise in nuclear fuel cycle signatures, separations chemistry, plutonium chemistry, environmental monitoring, modeling and analysis of reactor systems, and nuclear material safeguards and security. From these Hanford origins, PNNL has grown into a multi-program science and engineering enterprise that utilizes this diversity to strengthen the international safeguards regime. Today, PNNL supports the International Atomic Energy Agency (IAEA) in its mission to provide assurances to the international community that nations domore » not use nuclear materials and equipment outside of peaceful uses. PNNL also serves in the IAEA’s Network of Analytical Laboratories (NWAL) by providing analysis of environmental samples gathered around the world. PNNL is involved in safeguards research and development activities in support of many U.S. Government programs such as the National Nuclear Security Administration’s (NNSA) Office of Research and Development, NNSA Office of Nonproliferation and Arms Control, and the U.S. Support Program to IAEA Safeguards. In addition to these programs, PNNL invests internal resources including safeguards-specific training opportunities for staff, and laboratory-directed research and development funding to further ideas that may grow into new capabilities. This paper and accompanying presentation highlight some of PNNL’s contributions in technology development, implementation concepts and approaches, policy, capacity building, and human capital development, in the field of international safeguards.« less
-
Gastelum, Zoe Nellie; Matzen, Laura E.; Smartt, Heidi A.; ...
2017-06-01
Today’s international nuclear safeguards inspectors have access to an increasing volume of supplemental information about the facilities under their purview, including commercial satellite imagery, nuclear trade data, open source information, and results from previous safeguards activities. In addition to completing traditional in-field safeguards activities, inspectors are now responsible for being able to act upon this growing corpus of supplemental safeguards-relevant data and for maintaining situational awareness of unusual activities taking place in their environment. However, cognitive science research suggests that maintaining too much information can be detrimental to a user’s understanding, and externalizing information (for example, to a mobile device)more » to reduce cognitive burden can decrease cognitive function related to memory, navigation, and attention. Given this dichotomy, how can international nuclear safeguards inspectors better synthesize information to enhance situational awareness, decision making, and performance in the field? This paper examines literature from the fields of cognitive science and human factors in the areas of wayfinding, situational awareness, equipment and technical assistance, and knowledge transfer, and describes the implications for the provision of, and interaction with, safeguards-relevant information for international nuclear safeguards inspectors working in the field.« less
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gastelum, Zoe Nellie; Matzen, Laura E.; Smartt, Heidi A.
Today’s international nuclear safeguards inspectors have access to an increasing volume of supplemental information about the facilities under their purview, including commercial satellite imagery, nuclear trade data, open source information, and results from previous safeguards activities. In addition to completing traditional in-field safeguards activities, inspectors are now responsible for being able to act upon this growing corpus of supplemental safeguards-relevant data and for maintaining situational awareness of unusual activities taking place in their environment. However, cognitive science research suggests that maintaining too much information can be detrimental to a user’s understanding, and externalizing information (for example, to a mobile device)more » to reduce cognitive burden can decrease cognitive function related to memory, navigation, and attention. Given this dichotomy, how can international nuclear safeguards inspectors better synthesize information to enhance situational awareness, decision making, and performance in the field? This paper examines literature from the fields of cognitive science and human factors in the areas of wayfinding, situational awareness, equipment and technical assistance, and knowledge transfer, and describes the implications for the provision of, and interaction with, safeguards-relevant information for international nuclear safeguards inspectors working in the field.« less
-
43 CFR 2462.4 - Segregative effect of publication.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Segregative effect of publication. 2462.4... Disposal Classification Procedure: Over 2,560 Acres § 2462.4 Segregative effect of publication. (a) Publication in the Federal Register of a notice of proposed classification pursuant to § 2462.1 or of a notice...
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pepper, Susan E.; Pickett, Chris A.; Queirolo, Al
The U.S Department of Energy (DOE) National Nuclear Security Administration (NNSA) Next Generation Safeguards Initiative (NGSI) and the International Atomic Energy Agency (IAEA) convened a workshop on Software Sustainability for Safeguards Instrumentation in Vienna, Austria, May 6-8, 2014. Safeguards instrumentation software must be sustained in a changing environment to ensure existing instruments can continue to perform as designed, with improved security. The approaches to the development and maintenance of instrument software used in the past may not be the best model for the future and, therefore, the organizers’ goal was to investigate these past approaches and to determine an optimalmore » path forward. The purpose of this report is to provide input for the DOE NNSA Office of International Nuclear Safeguards (NA-241) and other stakeholders that can be utilized when making decisions related to the development and maintenance of software used in the implementation of international nuclear safeguards. For example, this guidance can be used when determining whether to fund the development, upgrade, or replacement of a particular software product. The report identifies the challenges related to sustaining software, and makes recommendations for addressing these challenges, supported by summaries and detailed notes from the workshop discussions. In addition the authors provide a set of recommendations for institutionalizing software sustainability practices in the safeguards community. The term “software sustainability” was defined for this workshop as ensuring that safeguards instrument software and algorithm functionality can be maintained efficiently throughout the instrument lifecycle, without interruption and providing the ability to continue to improve that software as needs arise.« less
-
ERIC Educational Resources Information Center
Holland, Sally; Tannock, Stuart; Collicott, Hayley
2011-01-01
The paper reviews public discourses and research on the safeguarding of other people's children by adults at the neighbourhood level. There is much empirical evidence pointing to the existence of thriving informal communities of support and informal childcare for parents across the social classes. There appears to be less empirical evidence…
-
WE-AB-206-02: ACR Ultrasound Accreditation: Requirements and Pitfalls
DOE Office of Scientific and Technical Information (OSTI.GOV)
Walter, J.
The involvement of medical physicists in diagnostic ultrasound imaging service is increasing due to QC and accreditation requirements. The goal of this ultrasound hands-on workshop is to demonstrate quality control (QC) testing in diagnostic ultrasound and to provide updates in ACR ultrasound accreditation requirements. The first half of this workshop will include two presentations reviewing diagnostic ultrasound QA/QC and ACR ultrasound accreditation requirements. The second half of the workshop will include live demonstrations of basic QC tests. An array of ultrasound testing phantoms and ultrasound scanners will be available for attendees to learn diagnostic ultrasound QC in a hands-on environmentmore » with live demonstrations and on-site instructors. The targeted attendees are medical physicists in diagnostic imaging. Learning Objectives: Gain familiarity with common elements of a QA/QC program for diagnostic ultrasound imaging dentify QC tools available for testing diagnostic ultrasound systems and learn how to use these tools Learn ACR ultrasound accreditation requirements Jennifer Walter is an employee of American College of Radiology on Ultrasound Accreditation.« less
-
NORTHROP REACTOR. REVISION NO. 1 TO THE FINAL SAFEGUARDS REPORT
DOE Office of Scientific and Technical Information (OSTI.GOV)
Duncan, J.M.; Shimizu, B.; Romine, R.A.
1962-10-01
Additions and changes related to the original application concerning construction and operation of the Northrop Reactor are given. Answers to 13 questions relative to the Final Safeguards Report are included. Answers are also included concerning 12 questions regarding receipt, possession, and storage of fuel elements. Other information is included concerning personnel changes and changes from Al-clad fuel elements to improved stainless steelclad hydride elements. It is concluded that the improved Northrop Reactor does not present any undue hazard to the health and safety of the operating personnel or the public. (J.R.D.)
-
Superfund Record of Decision (EPA Region 1): Salem Acres Site, Salem, MA, March 1993
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
This decision document represents the selected remedial action for the Salem Acres Site in Salem, Massachusetts. The remedial action for the Salem Acres Site, as described in this ROD, addresses the principal threats to the human health and the environment posed by exposure of humans to contaminated soils from the Salem Acres Site. This remedy addresses all principal threats to human health and the environment posed by the sources of contamination at the Site resulting from dermal absorption and incidental ingestion of contaminants in surficial soils.
-
Using the ACR/NEMA standard with TCP/IP and Ethernet
NASA Astrophysics Data System (ADS)
Chimiak, William J.; Williams, Rodney C.
1991-07-01
There is a need for a consolidated picture archival and communications system (PACS) in hospitals. At the Bowman Gray School of Medicine of Wake Forest University (BGSM), the authors are enhancing the ACR/NEMA Version 2 protocol using UNIX sockets and TCP/IP to greatly improve connectivity. Initially, nuclear medicine studies using gamma cameras are to be sent to PACS. The ACR/NEMA Version 2 protocol provides the functionality of the upper three layers of the open system interconnection (OSI) model in this implementation. The images, imaging equipment information, and patient information are then sent in ACR/NEMA format to a software socket. From there it is handed to the TCP/IP protocol, which provides the transport and network service. TCP/IP, in turn, uses the services of IEEE 802.3 (Ethernet) to complete the connectivity. The advantage of this implementation is threefold: (1) Only one I/O port is consumed by numerous nuclear medicine cameras, instead of a physical port for each camera. (2) Standard protocols are used which maximize interoperability with ACR/NEMA compliant PACSs. (3) The use of sockets allows a migration path to the transport and networking services of OSIs TP4 and connectionless network service as well as the high-performance protocol being considered by the American National Standards Institute (ANSI) and the International Standards Organization (ISO) -- the Xpress Transfer Protocol (XTP). The use of sockets also gives access to ANSI's Fiber Distributed Data Interface (FDDI) as well as other high-speed network standards.
-
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-21
... textile and apparel safeguard provisions, provided for in Article 3.1 of the United States-Oman Free Trade... customs duty under the Agreement, an Omani textile or apparel article is being imported into the United... article, and under such conditions as to cause serious damage or actual threat thereof to a U.S. industry...
-
Inhibition Mechanism of an Anti-CRISPR Suppressor AcrIIA4 Targeting SpyCas9.
Yang, Hui; Patel, Dinshaw J
2017-07-06
Prokaryotic CRISPR-Cas adaptive immune systems utilize sequence-specific RNA-guided endonucleases to defend against infection by viruses, bacteriophages, and mobile elements, while these foreign genetic elements evolve diverse anti-CRISPR proteins to overcome the CRISPR-Cas-mediated defense of the host. Recently, AcrIIA2 and AcrIIA4, encoded by Listeria monocytogene prophages, were shown to block the endonuclease activity of type II-A Streptococcus pyogene Cas9 (SpyCas9). We now report the crystal structure of AcrIIA4 in complex with single-guide RNA-bound SpyCas9, thereby establishing that AcrIIA4 preferentially targets critical residues essential for PAM duplex recognition, as well as blocks target DNA access to key catalytic residues lining the RuvC pocket. These structural insights, validated by biochemical assays on key mutants, demonstrate that AcrIIA4 competitively occupies both PAM-interacting and non-target DNA strand cleavage catalytic pockets. Our studies provide insights into anti-CRISPR-mediated suppression mechanisms for inactivating SpyCas9, thereby broadening the applicability of CRISPR-Cas regulatory tools for genome editing. Published by Elsevier Inc.
-
Improving Transparency in the Reporting of Safeguards Implementation: FY11 Update
DOE Office of Scientific and Technical Information (OSTI.GOV)
Toomey, Christopher; Odlaug, Christopher S.; Wyse, Evan T.
2011-09-30
In 2008, the Standing Advisory Group on Safeguards Implementation (SAGSI) indicated that the International Atomic Energy Agency's (IAEA) Safeguards Implementation Report (SIR) has not kept pace with the evolution of safeguards and provided the IAEA with a set of recommendations for improvement. The SIR is the primary mechanism for providing an overview of safeguards implementation in a given year and reporting on the annual safeguards findings and conclusions drawn by the Secretariat. As the IAEA transitions to State-level safeguards approaches, SIR reporting must adapt to reflect these evolutionary changes. This evolved report will better reflect the IAEA's transition to amore » more qualitative and information-driven approach, based upon State-as-a-whole considerations. This paper applies SAGSI's recommendations to the development of multiple models for an evolved SIR and finds that an SIR repurposed as a 'safeguards portal' could significantly enhance information delivery, clarity, and transparency. In addition, this paper finds that the 'portal concept' also appears to have value as a standardized information presentation and analysis platform for use by Country Officers, for continuity of knowledge purposes, and the IAEA Secretariat in the safeguards conclusion process. Accompanying this paper is a fully functional prototype of the 'portal' concept, built using commercial software and IAEA Annual Report data and available for viewing at http://safeguardsportal.pnnl.gov.« less
-
THE NEXT GENERATION SAFEGUARDS PROFESSIONAL NETWORK: PROGRESS AND NEXT STEPS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhernosek, Alena V; Lynch, Patrick D; Scholz, Melissa A
2011-01-01
President Obama has repeatedly stated that the United States must ensure that the international safeguards regime, as embodied by the International Atomic Energy Agency (IAEA), has 'the authority, information, people, and technology it needs to do its job.' The U.S. Department of Energy (DOE) National Nuclear Security Administration (NNSA) works to implement the President's vision through the Next Generation Safeguards Initiative (NGSI), a program to revitalize the U.S. DOE national laboratories safeguards technology and human capital base so that the United States can more effectively support the IAEA and ensure that it meets current and emerging challenges to the internationalmore » safeguards system. In 2009, in response to the human capital development goals of NGSI, young safeguards professionals within the Global Nuclear Security Technology Division at Oak Ridge National Laboratory launched the Next Generation Safeguards Professional Network (NGSPN). The purpose of this initiative is to establish working relationships and to foster collaboration and communication among the next generation of safeguards leaders. The NGSPN is an organization for, and of, young professionals pursuing careers in nuclear safeguards and nonproliferation - as well as mid-career professionals new to the field - whether working within the U.S. DOE national laboratory complex, U.S. government agencies, academia, or industry or at the IAEA. The NGSPN is actively supported by the NNSA, boasts more than 70 members, maintains a website and newsletter, and has held two national meetings as well as an NGSPN session and panel at the July 2010 Institute of Nuclear Material Management Annual Meeting. This paper discusses the network; its significance, goals and objectives; developments and progress to date; and future plans.« less
-
Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium
Wang-Kan, Xuan; Chirullo, Barbara; Betts, Jonathan; La Ragione, Roberto M.; Ivens, Alasdair; Ricci, Vito; Opperman, Timothy J.
2017-01-01
ABSTRACT AcrAB-TolC is the paradigm resistance-nodulation-division (RND) multidrug resistance efflux system in Gram-negative bacteria, with AcrB being the pump protein in this complex. We constructed a nonfunctional AcrB mutant by replacing D408, a highly conserved residue essential for proton translocation. Western blotting confirmed that the AcrB D408A mutant had the same native level of expression of AcrB as the parental strain. The mutant had no growth deficiencies in rich or minimal medium. However, compared with wild-type SL1344, the mutant had increased accumulation of Hoechst 33342 dye and decreased efflux of ethidium bromide and was multidrug hypersusceptible. The D408A mutant was attenuated in vivo in mouse and Galleria mellonella models and showed significantly reduced invasion into intestinal epithelial cells and macrophages in vitro. A dose-dependent inhibition of invasion was also observed when two different efflux pump inhibitors were added to the wild-type strain during infection of epithelial cells. RNA sequencing (RNA-seq) revealed downregulation of bacterial factors necessary for infection, including those in the Salmonella pathogenicity islands 1, 2, and 4; quorum sensing genes; and phoPQ. Several general stress response genes were upregulated, probably due to retention of noxious molecules inside the bacterium. Unlike loss of AcrB protein, loss of efflux function did not induce overexpression of other RND efflux pumps. Our data suggest that gene deletion mutants are unsuitable for studying membrane transporters and, importantly, that inhibitors of AcrB efflux function will not induce expression of other RND pumps. PMID:28720734
-
Health Information Security in Hospitals: the Application of Security Safeguards.
Mehraeen, Esmaeil; Ayatollahi, Haleh; Ahmadi, Maryam
2016-02-01
A hospital information system has potentials to improve the accessibility of clinical information and the quality of health care. However, the use of this system has resulted in new challenges, such as concerns over health information security. This paper aims to assess the status of information security in terms of administrative, technical and physical safeguards in the university hospitals. This was a survey study in which the participants were information technology (IT) managers (n=36) who worked in the hospitals affiliated to the top ranked medical universities (university A and university B). Data were collected using a questionnaire. The content validity of the questionnaire was examined by the experts and the reliability of the questionnaire was determined using Cronbach's coefficient alpha (α=0.75). The results showed that the administrative safeguards were arranged at a medium level. In terms of the technical safeguards and the physical safeguards, the IT managers rated them at a strong level. According to the results, among three types of security safeguards, the administrative safeguards were assessed at the medium level. To improve it, developing security policies, implementing access control models and training users are recommended.
-
Safeguards and security research and development: Progress report, October 1994--September 1995
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rutherford, D.R.; Henriksen, P.W.
The primary goal of the Los Alamos Safeguards and Security Technology Development Program, International Safeguards, and other Safeguards and Security Programs is to continue to be the center of excellence in the field of Safeguards and Security. This annual report for 1995 describes those scientific and engineering projects that contribute to all of the aforementioned programs. The authors have presented the information in a different format from previous annual reports. Part I is devoted to Nuclear Material Measurement Systems. Part II contains projects that are specific to Integrated Safeguards Systems. Part III highlights Safeguards Systems Effectiveness Evaluations and Part IVmore » is a compilation of highlights from Information Assurance projects. Finally Part V highlights work on the projects at Los Alamos for International Safeguards. The final part of this annual report lists titles and abstracts of Los Alamos Safeguards and Security Technology Development reports, technical journal articles, and conference papers that were presented and published in 1995. This is the last annual report in this format. The authors wish to thank all of the individuals who have contributed to this annual report and made it so successful over the years.« less
-
Pletzer, Daniel; Weingart, Helge
2014-01-21
Multidrug efflux pumps are membrane translocases that have the ability to extrude a variety of structurally unrelated compounds from the cell. AcrD, a resistance-nodulation-cell division (RND) transporter, was shown to be involved in efflux of highly hydrophilic aminoglycosides and a limited number of amphiphilic compounds in E. coli. Here, a homologue of AcrD in the plant pathogen and causal agent of fire blight disease Erwinia amylovora was identified. The substrate specificity of AcrD was studied by overexpression of the corresponding gene from a high-copy plasmid in E. amylovora Ea1189-3, which is hypersensitive to many drugs due to a deficiency of the major multidrug pump AcrB. AcrD mediated resistance to several amphiphilic compounds including clotrimazole and luteolin, two compounds hitherto not described as substrates of AcrD in enterobacteria. However, AcrD was not able to expel aminoglycosides. An acrD mutant exhibited full virulence on apple rootstock and immature pear fruits. RT-PCR analysis revealed an induction of acrD expression in infected apple tissue but not on pear fruits. Moreover, a direct binding of BaeR, the response regulator of the two-component regulatory system BaeSR, to the acrD promoter was observed as has already been shown in other enterobacteria. AcrD from E. amylovora is involved in resistance to a limited number of amphiphilic compounds, but in contrast to AcrD of E. coli, it is not involved in resistance to aminoglycosides. The expression of acrD was up-regulated by addition of the substrates deoxycholate, naringenin, tetracycline and zinc. AcrD appears to be regulated by the BaeSR two-component system, an envelope stress signal transduction pathway.
-
2014-01-01
Background Multidrug efflux pumps are membrane translocases that have the ability to extrude a variety of structurally unrelated compounds from the cell. AcrD, a resistance-nodulation-cell division (RND) transporter, was shown to be involved in efflux of highly hydrophilic aminoglycosides and a limited number of amphiphilic compounds in E. coli. Here, a homologue of AcrD in the plant pathogen and causal agent of fire blight disease Erwinia amylovora was identified. Results The substrate specificity of AcrD was studied by overexpression of the corresponding gene from a high-copy plasmid in E. amylovora Ea1189-3, which is hypersensitive to many drugs due to a deficiency of the major multidrug pump AcrB. AcrD mediated resistance to several amphiphilic compounds including clotrimazole and luteolin, two compounds hitherto not described as substrates of AcrD in enterobacteria. However, AcrD was not able to expel aminoglycosides. An acrD mutant exhibited full virulence on apple rootstock and immature pear fruits. RT-PCR analysis revealed an induction of acrD expression in infected apple tissue but not on pear fruits. Moreover, a direct binding of BaeR, the response regulator of the two-component regulatory system BaeSR, to the acrD promoter was observed as has already been shown in other enterobacteria. Conclusions AcrD from E. amylovora is involved in resistance to a limited number of amphiphilic compounds, but in contrast to AcrD of E. coli, it is not involved in resistance to aminoglycosides. The expression of acrD was up-regulated by addition of the substrates deoxycholate, naringenin, tetracycline and zinc. AcrD appears to be regulated by the BaeSR two-component system, an envelope stress signal transduction pathway. PMID:24443882
-
McDonald, Katherine E; Conroy, Nicole E; Kim, Carolyn I; LoBraico, Emily J; Prather, Ellis M; Olick, Robert S
2016-12-01
Human subjects research has a core commitment to participant well-being. This obligation is accentuated for once exploited populations such as adults with intellectual disability. Yet we know little about the public's views on appropriate safeguards for this population. We surveyed adults with intellectual disability, family members and friends, disability service providers, researchers, and Institutional Review Board (IRB) members to compare views on safeguards. We found many points of convergence of views, particularly for decision-making and participation. One trend is that adults with intellectual disability perceive greater safety in being engaged directly in recruitment, and recruitment by specific individuals. Researchers and IRB members need to consider community views to facilitate the safe and respectful inclusion of adults with intellectual disability.
-
NASA Astrophysics Data System (ADS)
Alzner, Edgar; Murphy, Laura
1986-06-01
The growing digital nature of radiology images led to a recognition that compatibility of communication between imaging, display and data storage devices of different modalities and different manufacturers is necessary. The ACR-NEMA Digital Imaging and Communications Standard Committee was formed to develop a communications standard for radiological images. This standard includes the overall structure of a communication message and the protocols for bi-directional communication using end-to-end connections. The evolution and rationale of the ACR-NEMA Digital Imaging and Communication Standard are described. An overview is provided and sane practical implementation considerations are discussed. PACS will became reality only if the medical community accepts and implements the ACR-NEMA Standard.
-
30 CFR 77.1008 - Relocation of drills; safeguards.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Relocation of drills; safeguards. 77.1008... COAL MINES Ground Control § 77.1008 Relocation of drills; safeguards. (a) When a drill is being moved from one drilling area to another, drill steel, tools, and other equipment shall be secured and the...
-
30 CFR 77.1008 - Relocation of drills; safeguards.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Relocation of drills; safeguards. 77.1008... COAL MINES Ground Control § 77.1008 Relocation of drills; safeguards. (a) When a drill is being moved from one drilling area to another, drill steel, tools, and other equipment shall be secured and the...
-
30 CFR 77.1008 - Relocation of drills; safeguards.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Relocation of drills; safeguards. 77.1008... COAL MINES Ground Control § 77.1008 Relocation of drills; safeguards. (a) When a drill is being moved from one drilling area to another, drill steel, tools, and other equipment shall be secured and the...
-
30 CFR 77.1008 - Relocation of drills; safeguards.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Relocation of drills; safeguards. 77.1008... COAL MINES Ground Control § 77.1008 Relocation of drills; safeguards. (a) When a drill is being moved from one drilling area to another, drill steel, tools, and other equipment shall be secured and the...
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
The Salem Acres, Incorporated site is a 235 acre parcel located in Salem, Essex County, Massachusetts. There are pits at the site which have apparently been filled with sewage sludge and tannery wastes. Organic compounds and metals have been found in the sludge in the pits, generally in the high parts-per-million range in very limited testing. Compounds detected in sludge included PCB-1254, lead, chromium, and mercury. Soil samples in the area did not show evident contamination. Off-site surface water had elevated levels of lead; two measurements were 64 ug/l and 89 ug/l, approximately. An oil sheen in surface water andmore » vegetation typical of polluted areas indicated water quality degradation. The site is considered to be of potential public health concern because of the risk to human health caused by the possibility of exposure to hazardous substances via continued direct exposure to soils, sediments and sludge residues in marginal areas of the site, and any consumption of any fish from the streams draining the site.« less
-
Discos de acresção em sistemas Be-X
NASA Astrophysics Data System (ADS)
Lopes de Oliveira, R.; Janot-Pacheco, E.
2003-08-01
Alguns fenômenos de outbursts em Be-X sugerem a existência, mesmo que temporária, de um disco de acresção quando da passagem do objeto compacto pelo periastro orbital. Neste trabalho avaliamos a possibilidade de formação do disco de acresção em sistemas Be+estrela de neutrons e Be+anã branca, e a influência da excentricidade orbital na ocorrência deste fenômeno. Utilizamos a expressão analítica para o momento angular específico da matéria constituinte de um meio em expansão lenta, como é o caso do disco circunstelar das estrelas Be, proposta por Wang(1981), sob a condição básica de que o raio de circularização deva ser maior do que o raio de Alfvén. Concluímos que existe um limite para o período orbital do sistema acima do qual não é possível a formação do disco de acresção, e que este valor aumenta para sistemas com excentricidade orbital maior.
-
19 CFR 206.46 - Public report.
Code of Federal Regulations, 2011 CFR
2011-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations for Relief From Market Disruption § 206.46 Public report. Upon making a...
-
19 CFR 206.46 - Public report.
Code of Federal Regulations, 2013 CFR
2013-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations for Relief From Market Disruption § 206.46 Public report. Upon making a...
-
19 CFR 206.46 - Public report.
Code of Federal Regulations, 2012 CFR
2012-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations for Relief From Market Disruption § 206.46 Public report. Upon making a...
-
19 CFR 206.46 - Public report.
Code of Federal Regulations, 2010 CFR
2010-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations for Relief From Market Disruption § 206.46 Public report. Upon making a...
-
19 CFR 206.46 - Public report.
Code of Federal Regulations, 2014 CFR
2014-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS Investigations for Relief From Market Disruption § 206.46 Public report. Upon making a...
-
Billings, M; Amin Hadavand, M; Alevizos, I
2018-03-01
The introduction of new classification criteria for Sjögren's syndrome, known as the 2016 American College of Rheumatology/European League against Rheumatism Classification Criteria (ACR-EULAR), created a need for the evaluation of its performance in an external cohort. The purpose of this study was to compare the performance of the 2016 ACR-EULAR classification set with the widely used American-European Consensus Group Classification criteria (AECG) in the cohort at the National Institutes of Health, USA, and to compare the performance of the sets in classifying both primary and secondary Sjögren's syndrome (pSS and sSS). The study cohort at the NIH (N = 1,303) was enrolled for clinical suspicion of SS. Participants were classified as SS, pSS, and sSS according to both classification sets. Performance of 2016 ACR-EULAR and AECG sets was compared holding each as gold standard to the other. Statistical analysis of test diagnostics and agreement between the two sets were undertaken. By the AECG set, 701 were classified as having SS (627 pSS, 74 sSS) and 714 were classified with SS (647 pSS, 67 sSS) by the 2016 ACR-EULAR set. Sensitivity and specificity of the two sets were comparable in classifying SS, pSS, and sSS. There was high agreement between the two sets for classifying SS (κ = 0.79), pSS (κ = 0.81), and sSS (κ = 0.87). The specificity of the 2016 ACR-EULAR set was significantly higher for classifying sSS than pSS, while the sensitivity was similar for the two disease groups. However, this pattern was also exhibited by the AECG set. There was high agreement between the two classification sets with comparable performance diagnostics. There was no evidence of superior performance value by the new 2016 ACR-EULAR set over the AECG set, and the two sets were found to be equivalent. Findings from our cohort indicate that 2016 ACR-EULAR classification could be extended to classification of sSS. Published 2018. This article is a U.S. Government work and
-
Chen, Yanshan; Xu, Wenzhong; Shen, Hongling; Yan, Huili; Xu, Wenxiu; He, Zhenyan; Ma, Mi
2013-08-20
Arsenic (As) pollution is a global problem, and the plant-based cleanup of contaminated soils, called phytoremediation, is therefore of great interest. Recently, transgenic approaches have been designed to develop As phytoremediation technologies. Here, we used a one-gene transgenic approach for As tolerance and accumulation in Arabidopsis thaliana . PvACR3, a key arsenite [As(III)] antiporter in the As hyperaccumulator fern Pteris vittata , was expressed in Arabidopsis , driven by the CaMV 35S promoter. In response to As treatment, PvACR3 transgenic plants showed greatly enhanced tolerance. PvACR3 transgenic seeds could even germinate and grow in the presence of 80 μM As(III) or 1200 μM arsenate [As(V)] treatments that were lethal to wild-type seeds. PvACR3 localizes to the plasma membrane in Arabidopsis and increases arsenite efflux into external medium in short-term experiments. Arsenic determination showed that PvACR3 substantially reduced As concentrations in roots and simultaneously increased shoot As under 150 μM As(V). When cultivated in As(V)-containing soil (10 ppm As), transgenic plants accumulated approximately 7.5-fold more As in above-ground tissues than wild-type plants. This study provides important insights into the behavior of PvACR3 and the physiology of As metabolism in plants. Our work also provides a simple and practical PvACR3 transgenic approach for engineering As-tolerant and -hyperaccumulating plants for phytoremediation.
-
Biofilm formation ability of Salmonella enterica serovar Typhimurium acrAB mutants.
Schlisselberg, Dov B; Kler, Edna; Kisluk, Guy; Shachar, Dina; Yaron, Sima
2015-10-01
Recent studies offer contradictory findings about the role of multidrug efflux pumps in bacterial biofilm development. Thus, the aim of this study was to investigate the involvement of the AcrAB efflux pump in biofilm formation by investigating the ability of AcrB and AcrAB null mutants of Salmonella enterica serovar Typhimurium to produce biofilms. Three models were used to compare the ability of S. Typhimurium wild-type and its mutants to form biofilms: formation of biofilm on polystyrene surfaces; production of biofilm (mat model) on the air/liquid interface; and expression of curli and cellulose on Congo red-supplemented agar plates. All three investigated genotypes formed biofilms with similar characteristics. However, upon exposure to chloramphenicol, formation of biofilms on solid surfaces as well as the production of curli were either reduced or were delayed more significantly in both mutants, whilst there was no visible effect on pellicle formation. It can be concluded that when no selective pressure is applied, S. Typhimurium is able to produce biofilms even when the AcrAB efflux pumps are inactivated, implying that the use of efflux pump inhibitors to prevent biofilm formation is not a general solution and that combined treatments might be more efficient. Other factors that affect the ability to produce biofilms depending on efflux pump activity are yet to be identified. Copyright © 2015 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.
-
2009-12-01
high standards of integrity, conduct, and concern for the public interest. 5. The Federal work force should be used efficiently and effectively . 6...NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) U.S. Government Accountability Office,441 G Street...in its implementation of DCIPS, DOD has taken some positive steps to incorporate 10 internal safeguards to help ensure the fair, effective , and
-
Safeguards Approaches for Black Box Processes or Facilities
DOE Office of Scientific and Technical Information (OSTI.GOV)
Diaz-Marcano, Helly; Gitau, Ernest TN; Hockert, John
2013-09-25
The objective of this study is to determine whether a safeguards approach can be developed for “black box” processes or facilities. These are facilities where a State or operator may limit IAEA access to specific processes or portions of a facility; in other cases, the IAEA may be prohibited access to the entire facility. The determination of whether a black box process or facility is safeguardable is dependent upon the details of the process type, design, and layout; the specific limitations on inspector access; and the restrictions placed upon the design information that can be provided to the IAEA. Thismore » analysis identified the necessary conditions for safeguardability of black box processes and facilities.« less
-
10 CFR 73.71 - Reporting of safeguards events.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 10 Energy 2 2014-01-01 2014-01-01 false Reporting of safeguards events. 73.71 Section 73.71 Energy... § 73.71 Reporting of safeguards events. (a)(1) Each licensee subject to the provisions of §§ 73.25, 73... revised information. Each licensee shall maintain a copy of the written report of an event submitted under...
-
10 CFR 73.71 - Reporting of safeguards events.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 2 2012-01-01 2012-01-01 false Reporting of safeguards events. 73.71 Section 73.71 Energy... § 73.71 Reporting of safeguards events. (a)(1) Each licensee subject to the provisions of §§ 73.25, 73... revised information. Each licensee shall maintain a copy of the written report of an event submitted under...
-
10 CFR 73.71 - Reporting of safeguards events.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 2 2013-01-01 2013-01-01 false Reporting of safeguards events. 73.71 Section 73.71 Energy... § 73.71 Reporting of safeguards events. (a)(1) Each licensee subject to the provisions of §§ 73.25, 73... revised information. Each licensee shall maintain a copy of the written report of an event submitted under...
-
Schneiders, T.; Amyes, S. G. B.; Levy, S. B.
2003-01-01
The MICs of ciprofloxacin for 33 clinical isolates of K. pneumoniae resistant to extended-spectrum cephalosporins from three hospitals in Singapore ranged from 0.25 to >128 μg/ml. Nineteen of the isolates were fluoroquinolone resistant according to the NCCLS guidelines. Strains for which the ciprofloxacin MIC was ≥0.5 μg/ml harbored a mutation in DNA gyrase A (Ser83→Tyr, Leu, or IIe), and some had a secondary Asp87→Asn mutation. Isolates for which the MIC was 16 μg/ml possessed an additional alteration in ParC (Ser80→IIe, Trp, or Arg). Tolerance of the organic solvent cyclohexane was observed in 10 of the 19 fluoroquinolone-resistant strains; 3 of these were also pentane tolerant. Five of the 10 organic solvent-tolerant isolates overexpressed AcrA and also showed deletions within the acrR gene. Complementation of the mutated acrR gene with the wild-type gene decreased AcrA levels and produced a two- to fourfold reduction in the fluoroquinolone MICs. None of the organic solvent-tolerant clinical isolates overexpressed another efflux-related gene, acrE. While marA and soxS were not overexpressed, another marA homologue, ramA, was overexpressed in 3 of 10 organic solvent-tolerant isolates. These findings indicate that multiple target and nontarget gene changes contribute to fluoroquinolone resistance in K. pneumoniae. Besides AcrR mutations, ramA overexpression (but not marA or soxS overexpression) was related to increased AcrAB efflux pump expression in this collection of isolates. PMID:12936981
-
19 CFR 206.68 - Public report.
Code of Federal Regulations, 2013 CFR
2013-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF... Public report. Upon making a report to the President of the results of an investigation under section 422...
-
19 CFR 206.68 - Public report.
Code of Federal Regulations, 2010 CFR
2010-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF... Public report. Upon making a report to the President of the results of an investigation under section 422...
-
19 CFR 206.68 - Public report.
Code of Federal Regulations, 2011 CFR
2011-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF... Public report. Upon making a report to the President of the results of an investigation under section 422...
-
19 CFR 206.68 - Public report.
Code of Federal Regulations, 2012 CFR
2012-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF... Public report. Upon making a report to the President of the results of an investigation under section 422...
-
19 CFR 206.68 - Public report.
Code of Federal Regulations, 2014 CFR
2014-04-01
... RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF... Public report. Upon making a report to the President of the results of an investigation under section 422...
-
5 CFR 293.107 - Special safeguards for automated records.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Special safeguards for automated records. 293.107 Section 293.107 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL RECORDS Basic Policies on Maintenance of Personnel Records § 293.107 Special safeguards...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-17
... Partial Change of Use of Public Lands in Clark County, NV AGENCY: Bureau of Land Management, Interior.... The city proposes to change the use of 10 acres from a public park and police substation to a safety village. DATES: Interested parties may submit written comments regarding the proposed change of use of the...
-
Exploratory study on potential safeguards applications for shared ledger technology
DOE Office of Scientific and Technical Information (OSTI.GOV)
Frazar, Sarah L.; Jarman, Kenneth D.; Joslyn, Cliff A.
The International Atomic Energy Agency (IAEA) is responsible for providing credible assurance that countries are meeting their obligations not to divert or misuse nuclear materials and facilities for non-peaceful purposes. To this end, the IAEA integrates information about States’ nuclear material inventories and transactions with other types of data to draw its safeguards conclusions. As the amount and variety of data and information has increased, the IAEA’s data acquisition, management, and analysis processes have greatly benefited from advancements in computer science, data management, and cybersecurity during the last 20 years. Despite these advancements, inconsistent use of advanced computer technologies asmore » well as political concerns among certain IAEA Member States centered on trust, transparency, and IAEA authorities limit the overall effectiveness and efficiency of IAEA safeguards. As a result, there is an ongoing need to strengthen the effectiveness and efficiency of IAEA safeguards while improving Member State cooperation and trust in the safeguards system. These chronic safeguards needs could be met with some emerging technologies, specifically those associated with the digital currency bitcoin.« less
-
Pakzad, Iraj; Zayyen Karin, Maasoume; Taherikalani, Morovat; Boustanshenas, Mina; Lari, Abdolaziz Rastegar
2013-01-01
Resistance to fluoroquinolones has been recently increased among bacterial strains isolated from outpatients. Multidrug-resistant K. pneumoniae is one of the major organisms isolated from burn patients and the AcrAB efflux pump is the principal pump contributing to the intrinsic resistance in K. pneumoniae against multiple antimicrobial agents including ciprofloxacin and other fluoroquinolones. Fifty-two K. pneumoniae isolated from burn patients in Shahid Motahari hospital and confirmed by conventional biochemical tests. Antimicrobial susceptibility testing was done according to CLSI 2011 guidelines, to determine the antimicrobial resistance pattern of isolates. AcrA gene was detected among ciprofloxacin-resistant isolates by PCR assay. MICs to ciprofloxacin were measured with and without carbonyl cyanide 3-chlorophenylhydrazone (CCCP). Forty out of the 52 K. pneumoniae isolated from burn patients in Shahid Motahari hospital were resistant to ciprofloxacin according to breakpoint of CLSI guideline. PCR assay for acrA gene demonstrated that all ciprofloxacin-resistant isolates harbored acrA gene coding the membrane fusion protein AcrA and is a part of AcrAB efflux system. Among these isolates, 19 strains (47.5%) showed 2 to 32 fold reduction in MICs after using CCCP as an efflux pump inhibitor. The other 21 strains (52.5%) showed no disparity in MICs before and after using CCCP. In conclusion, the AcrAB efflux system is one of the principal mechanisms contribute in ciprofloxacin resistance among K. pneumoniae isolates but there are some other mechanisms interfere with ciprofloxacin resistance such as mutation in target proteins of DNA gyrase of topoisomerase IV enzymes.
-
10 CFR 1304.114 - Responsibility for maintaining adequate safeguards.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 4 2011-01-01 2011-01-01 false Responsibility for maintaining adequate safeguards. 1304.114 Section 1304.114 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.114 Responsibility for maintaining adequate safeguards. The Board has the responsibility for maintaining adequate...
-
10 CFR 1304.114 - Responsibility for maintaining adequate safeguards.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 10 Energy 4 2014-01-01 2014-01-01 false Responsibility for maintaining adequate safeguards. 1304.114 Section 1304.114 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.114 Responsibility for maintaining adequate safeguards. The Board has the responsibility for maintaining adequate...
-
10 CFR 1304.114 - Responsibility for maintaining adequate safeguards.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 4 2012-01-01 2012-01-01 false Responsibility for maintaining adequate safeguards. 1304.114 Section 1304.114 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.114 Responsibility for maintaining adequate safeguards. The Board has the responsibility for maintaining adequate...
-
10 CFR 1304.114 - Responsibility for maintaining adequate safeguards.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 4 2013-01-01 2013-01-01 false Responsibility for maintaining adequate safeguards. 1304.114 Section 1304.114 Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.114 Responsibility for maintaining adequate safeguards. The Board has the responsibility for maintaining adequate...
-
5 CFR 293.107 - Special safeguards for automated records.
Code of Federal Regulations, 2014 CFR
2014-01-01
... for automated records. (a) In addition to following the security requirements of § 293.106 of this... security safeguards for data about individuals in automated records, including input and output documents, reports, punched cards, magnetic tapes, disks, and on-line computer storage. The safeguards must be in...
-
5 CFR 293.107 - Special safeguards for automated records.
Code of Federal Regulations, 2013 CFR
2013-01-01
... for automated records. (a) In addition to following the security requirements of § 293.106 of this... security safeguards for data about individuals in automated records, including input and output documents, reports, punched cards, magnetic tapes, disks, and on-line computer storage. The safeguards must be in...
-
5 CFR 293.107 - Special safeguards for automated records.
Code of Federal Regulations, 2012 CFR
2012-01-01
... for automated records. (a) In addition to following the security requirements of § 293.106 of this... security safeguards for data about individuals in automated records, including input and output documents, reports, punched cards, magnetic tapes, disks, and on-line computer storage. The safeguards must be in...
-
5 CFR 293.107 - Special safeguards for automated records.
Code of Federal Regulations, 2011 CFR
2011-01-01
... for automated records. (a) In addition to following the security requirements of § 293.106 of this... security safeguards for data about individuals in automated records, including input and output documents, reports, punched cards, magnetic tapes, disks, and on-line computer storage. The safeguards must be in...
-
Safeguards Knowledge Management & Retention at U.S. National Laboratories.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Haddal, Risa; Jones, Rebecca; Bersell, Bridget
In 2017, four U.S. National Laboratories collaborated on behalf of DOE/NNSA to explore the safeguards knowledge retention problem, identify possible approaches, and develop a strategy to address it. The one-year effort consisted of four primary tasks. First, the project sought to identify critical safeguards information at risk of loss. Second, a survey and workshop were conducted to assess nine U.S. National Laboratories' efforts to determine current safeguards knowledge retention practices and challenges, and identify best practices. Third, specific tools were developed to identify and predict critical safeguards knowledge gaps and how best to recruit in order to fill those gaps.more » Finally, based on findings from the first three tasks and research on other organizational approaches to address similar issues, a strategy was developed on potential knowledge retention methods, customized HR policies, and best practices that could be implemented across the National Laboratory Complex.« less
-
48 CFR 52.239-1 - Privacy or Security Safeguards.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Privacy or Security....239-1 Privacy or Security Safeguards. As prescribed in 39.107, insert a clause substantially the same as the following: Privacy or Security Safeguards (AUG 1996) (a) The Contractor shall not publish or...
-
48 CFR 52.239-1 - Privacy or Security Safeguards.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Privacy or Security....239-1 Privacy or Security Safeguards. As prescribed in 39.107, insert a clause substantially the same as the following: Privacy or Security Safeguards (AUG 1996) (a) The Contractor shall not publish or...
-
48 CFR 52.239-1 - Privacy or Security Safeguards.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Privacy or Security....239-1 Privacy or Security Safeguards. As prescribed in 39.107, insert a clause substantially the same as the following: Privacy or Security Safeguards (AUG 1996) (a) The Contractor shall not publish or...
-
48 CFR 52.239-1 - Privacy or Security Safeguards.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Privacy or Security....239-1 Privacy or Security Safeguards. As prescribed in 39.107, insert a clause substantially the same as the following: Privacy or Security Safeguards (AUG 1996) (a) The Contractor shall not publish or...
-
48 CFR 52.239-1 - Privacy or Security Safeguards.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Privacy or Security....239-1 Privacy or Security Safeguards. As prescribed in 39.107, insert a clause substantially the same as the following: Privacy or Security Safeguards (AUG 1996) (a) The Contractor shall not publish or...
-
17 CFR 37.1400 - Core Principle 14-System safeguards.
Code of Federal Regulations, 2014 CFR
2014-04-01
... procedures, and automated systems, that: (1) Are reliable and secure; and (2) Have adequate scalable capacity... 17 Commodity and Securities Exchanges 1 2014-04-01 2014-04-01 false Core Principle 14-System... SWAP EXECUTION FACILITIES System Safeguards § 37.1400 Core Principle 14—System safeguards. The swap...
-
ACR Electrical Systems. Teacher Edition [and] Student Edition.
ERIC Educational Resources Information Center
Clemons, Mark
This document contains a teacher's guide and student guide for a high school-level competency-based course in air conditioning and refrigeration (ACR) equipment electrical systems. Presented in the teacher's guide are the following: explanation of the instructional units' use; competency profile for recording students' performance of the tasks in…
-
Potential application of LIBS to NNSA next generation safeguards initiative (NGSI)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Barefield Ii, James E; Clegg, Samuel M; Veirs, Douglas K
2009-01-01
In a climate in which states and nations have been and perhaps currently are involved in the prol iferation of nuclear materials and technologies, advanced methodologies and improvements in current measurement techniques are needed to combat new threats and increased levels of sophistication. The Department of Energy through the National Nuclear Security Administration (NNSA) has undertaken a broad review of International Safeguards. The conclusion from that review was that a comprehensive initiative to revitalize international safeguards technology and the human resource base was urgently needed to keep pace with demands and increasingly sophisticated emerging safeguards challenges. To address these challenges,more » NNSA launched the Next Generation Safeguards Initiative (NGSI) to develop policies, concepts, technologies, expertise, and infrastructure necessary to sustain the international safeguards system as its mission evolves for the next 25 years. NGSI is designed to revitalize and strengthen the U.S. safeguards technical base, recognizing that without a robust program the United States of America will not be in a position to exercise leadership or provide the necessary support to the IAEA (International Atomic Energy Agency). International safeguards as administrated by the IAEA are the primary vehicle for verifying compliance with the peaceful use and nonproliferation of nuclear materials and technologies. Laser Induced Breakdown Spectroscopy or LIBS has the potential to support the goals of NGSI as follows: by providing (1) automated analysis in complex nuclear processing or reprocessing facilities in real-time or near real-time without sample preparation or removal, (2) isotopic and important elemental ratio (Cm/Pu, Cm/U, ... etc) analysis, and (3) centralized remote control, process monitoring, and analysis of nuclear materials in nuclear facilities at multiple locations within the facility. Potential application of LIBS to international safeguards as
-
Deterring Nuclear Proliferation: The Importance of IAEA Safeguards: A TEXTBOOK
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rosenthal, M.D.; Fishbone, L.G.; Gallini, L.
2012-03-13
Nuclear terrorism and nuclear proliferation are among the most pressing challenges to international peace and security that we face today. Iran and Syria remain in non-compliance with the safeguards requirements of the NPT, and the nuclear ambitions of North Korea remain unchecked. Despite these challenges, the NPT remains a cornerstone of the nuclear non-proliferation regime, and the safeguards implemented by the International Atomic Energy Agency (IAEA) under the NPT play a critical role in deterring nuclear proliferation.How do they work? Where did they come from? And what is their future? This book answers these questions. Anyone studying the field ofmore » nuclear non-proliferation will benefit from reading this book, and for anyone entering the field, the book will enable them to get a running start. Part I describes the foundations of the international safeguards system: its origins in the 1930s - when new discoveries in physics made it clear immediately that nuclear energy held both peril and promise - through the entry into force in 1970 of the NPT, which codified the role of IAEA safeguards as a means to verify states NPT commitments not to acquire nuclear weapons. Part II describes the NPT safeguards system, which is based on a model safeguards agreement developed specifically for the NPT, The Structure and Content of Agreements between the Agency and States required in connection with the Treaty on the Non-Proliferation of Nuclear Weapons, which has been published by the IAEA as INFCIRC/153. Part III describes events, especially in South Africa, the DPRK, and Iraq in the early 1990s, that triggered a transformation in the way in which safeguards were conceptualized and implemented.« less
-
"Capacity is key": investigating new legal provisions in England and Wales for adult safeguarding.
Manthorpe, Jill; Samsi, Kritika; Rapaport, Joan
2013-01-01
This study aimed to investigate the views and experiences of local Safeguarding Adults Coordinators of the newly implemented Mental Capacity Act 2005. This legislation in England and Wales has both protection and empowerment as its dual goals. Fifteen Safeguarding Adults Coordinators (SACs) employed by local authorities in the London area were interviewed in 2008, and again 2 years later. A total of 12 SACs participated in the 2010 follow-up interviews. The findings are reported here, covering experiences and views on the implementation and uses of the Act. There was overwhelming support for the Act as enhancing people's rights to a life free from abuse, of providing a framework for the assessment of decision-making capacity, and of assisting practitioners in reducing risks and responding to abusive situations. Participants urged better publicity about the Act, more detailed guidance on the new offenses, and greater attention to the interactions with other government policy goals.
-
A Priority-Based View of Future Challenges in International Nuclear Safeguards.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Matteucci, Kayla
The international nuclear safeguards community is faced with a host of challenges in the coming years, many of which have been outlined but have not been described in terms of their urgency. Literature regarding safeguards challenges is either broad and devoid of any reference to prioritization or tailored to a specific problem and removed from the overall goals of the safeguards community. For example, developing new methods of environmental sampling, improving containment and surveillance (C/S) technologies to increase efficiency and decrease inspection time, advancing nuclear material accountancy (NMA) techniques, and planning safeguards approaches for new types of nuclear facilities aremore » all important. They have not, however, been distinctly prioritized at a high level within the safeguards community. Based on a review of existing literature and interviews with experts on these upcoming challenges, this paper offers a high-level summary of present and future priorities in safeguards, with attention both to what is feasible and to what is most imperative. In doing so, the paper addresses the potential repercussions for failing to prioritize, with a focus on the risk of diversion of nuclear material. Within the context of shifts in the American political landscape, and keeping in mind that nonproliferation issues may take a backseat to others in the near future, a prioritized view of safeguards objectives will be vital. In the interest of expanding upon this work, the paper offers several potential conceptual models for prioritization which can be explored in greater depth upon further research.« less
-
Multidrug efflux transporter, AcrB--the pumping mechanism.
Murakami, Satoshi
2008-08-01
Resistance nodulation cell division (RND) transporters are one of the main causes of the bacterial multidrug resistance. They pump a wide range of antibiotics out of the cell by proton motive force. AcrB is the major RND transporter in Escherichia coli. Recently, the crystal structures of AcrB have been determined by different space groups. All these structures are consistent with asymmetric trimer. Each monomer has different conformation corresponding to one of the three functional states of the transport cycle. Transporting hydrophobic drug was bound in the periplasmic domain on one of the three monomers. The transport pathway with alternating access mechanism is located at the hydrophilic domain protruded into the periplasmic space while this mechanism of other transporter families like ATP binding cassette (ABC) and major facilitator superfamily (MFS) transporter is located in the membrane-embedded region. For the RND, protonation might also take place asymmetrically at the functionally important charged residues in the transmembrane (TM) region. The structures indicate that drugs are transported by a three-step functional rotation in which substrates undergo ordered binding change.
-
National Woodland Owner Survey: family forest ownerships with 1 to 9 acres, 2011-2013
Brett J. Butler; Stephanie A. Snyder
2017-01-01
This report summarizes results from the 2011-2013 National Woodland Owner Survey (NWOS) conducted by the U.S. Forest Service, Forest Inventory and Analysis program for family forest ownerships with forest holdings of 1-9 acres. Summaries are based on responses from 1,025 family ownerships with 1-9 acres of forest across 39 U.S. states. Survey summary tables are...
-
Implementation of IT-based applications in the safeguards field
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ekenstam, G.C. af; Sallstrom, M.
1995-12-31
For many years the Swedish Nuclear Power Inspectorate, SKI, has used computers as a tool within nuclear material control and accountancy. Over the last five years a lot of effort has been put into projects related to the increasing possibilities of fast and reliable data transfer over large distances. The paper discusses related administrative and technical issues and presents experience gained in tasks of the Swedish Support Program to IAEA Safeguards and during the alternative Safeguards trials carried out by SKI. The following topics will be presented: (1) Main Safeguards purposes and data transfer; (2) Administrative systems and requirements; (3)more » Technical possibilities and experiences; and (4) The cost aspect.« less
-
Keynote Address: ACR-NEMA standards and their implications for teleradiology
NASA Astrophysics Data System (ADS)
Horii, Steven C.
1990-06-01
The ACR-NEMA Standard was developed initially as an interface standard for the interconnection of two pieces of imaging equipment Essentially the Standard defmes a point-to-point hardware connection with the necessary protocol and data structure so that two differing devices which meet the specification will be able to communicate with each other. The Standard does not defme a particular PACS architecture nor does it specify a database structure. In part these are the reasons why implementers have had difficulty in using the Standard in a full PACS. Recent activity of the Working Groups formed by the Committee overseeing work on the ACR-NEMA Standard has changed some of the " flavor" of the Standard. It was realized that connection of PACS with hospital and radiology information systems (HIS and RIS) is necessary if a PACS is ever to be succesful. The idea of interconnecting heterogeneous computer systems has pushed Standards development beyond the scope of the original work. Teleradiology which inherenfly involves wide-area networking may be a direct beneficiary of the new directions taken by the Standards Working Groups. This paper will give a brief history of the ACR-NEMA effort describe the " parent" Standard and its " offspring" and describe the activity of the current Working Groups with particular emphasis on the potential impacts on teleradiology.
-
Gray squirrels reproduce in a 2-acre enclosure
H. Reed Sanderson; Larry A. Berry
1973-01-01
A 2-acre enclosure was built in a 40-year-old hardwood stand, and 5 to 19 gray squirrels (Sciurus carolinensis) were confined in it during 3 years. Reproductive behavior of the squirrels was the same at all population densities, but densities above 12 may have reduced productivity. For 10 to 12 squirrels, behavior was about normal and productivity...
-
14 CFR 1212.605 - Safeguarding information in systems of records.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Safeguarding information in systems of records. 1212.605 Section 1212.605 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS Instructions for NASA Employees § 1212.605 Safeguarding information in...
-
RECRUITMENT OF U.S. CITIZENS FOR VACANCIES IN IAEA SAFEGUARDS
DOE Office of Scientific and Technical Information (OSTI.GOV)
PEPPER,S.E.; DECARO,D.; WILLIAMS,G.
The International Atomic Energy Agency (IAEA) relies on its member states to assist with recruiting qualified individuals for positions within the IAEA's secretariat. It is important that persons within and outside the US nuclear and safeguards industries become aware of career opportunities available at the IAEA, and informed about important vacancies. The IAEA has established an impressive web page to advertise opportunities for employment. However, additional effort is necessary to ensure that there is sufficient awareness in the US of these opportunities, and assistance for persons interested in taking positions at the IAEA. In 1998, the Subgroup on Safeguards Technicalmore » Support (SSTS) approved a special task under the US Support Program to IAEA Safeguards (USSP) for improving US efforts to identify qualified candidates for vacancies in IAEA's Department of Safeguards. The International Safeguards Project Office (ISPO) developed a plan that includes increased advertising, development of a web page to support US recruitment efforts, feedback from the US Mission in Vienna, and interaction with other recruitment services provided by US professional organizations. The main purpose of this effort is to educate US citizens about opportunities at the IAEA so that qualified candidates can be identified for the IAEA's consideration.« less
-
IMPACT OF THE U.S. SUPPORT PROGRAM SAFEGUARDS INTERNSHIP PROGRAM.
DOE Office of Scientific and Technical Information (OSTI.GOV)
PEPPER, S.; OSIECKI, C.
2006-07-16
The U.S. Support Program began funding an internship program in the IAEA Department of Safeguards in 2002. Since that time, 39 U.S. citizens and permanent residents have been placed in one-year, paid internships with the IAEA. The management of the internship program was originally the responsibility of the International Safeguards Project Office but was transferred to the Office of Educational Programs at Brookhaven National Laboratory in 2004. Feedback on the internship program from the U.S. government and the IAEA has been positive. The interns have completed basic yet essential work for the Department of Safeguards and freed IAEA staff membersmore » to perform more complex tasks. The cost of an intern is low relative to other forms of human resources support. After the conclusion of their assignments, many of the interns go on to work for the U.S. government, the national laboratories, or companies in international safeguards and nonproliferation. This paper will discuss the work done by the interns for the IAEA, factors influencing the success of the internship program, and the effects the program has had on the careers of interns, in preparing the next generation to work in the nuclear industry, participation in INMM activities, and recruitment for U.S. citizens for safeguards positions.« less
-
ERIC Educational Resources Information Center
Earls, Alan R.
2003-01-01
Justin S. Morrill of Vermont began advocating for the Land Grant Act in the 1850s. The act's passage in 1862 provided a grant of 30,000 acres of public land for each member of a state's congressional delegation, to be sold to raise funds for the creation of agricultural and engineering colleges. While the original Land Grant provided grants of…
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pepper, Susan E.
2014-10-10
Brookhaven National Laboratory’s (BNL’s) Nonproliferation and National Security Department contributes to the National Nuclear Security Administration Office of Nonproliferation and International Security Next Generation Safeguards Initiative (NGSI) through university engagement, safeguards internships, safeguards courses, professional development, recruitment, and other activities aimed at ensuring the next generation of international safeguards professionals is adequately prepared to support the U.S. safeguards mission. This report is a summary of BNL s work under the NGSI program in Fiscal Year 2014.
-
10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 2 2011-01-01 2011-01-01 false Compliance with requirements of US/IAEA Safeguards... Authority in Agreement States § 150.17a Compliance with requirements of US/IAEA Safeguards Agreement. (a... shall take other action as may be necessary to implement the US/IAEA Safeguards Agreement, as described...
-
10 CFR 150.17a - Compliance with requirements of US/IAEA Safeguards Agreement.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 2 2010-01-01 2010-01-01 false Compliance with requirements of US/IAEA Safeguards... Authority in Agreement States § 150.17a Compliance with requirements of US/IAEA Safeguards Agreement. (a... shall take other action as may be necessary to implement the US/IAEA Safeguards Agreement, as described...
-
Code of Federal Regulations, 2011 CFR
2011-04-01
... Relations DEPARTMENT OF STATE GENERAL SECURITY INFORMATION REGULATIONS § 9.13 Safeguarding. Specific controls on the use, processing, storage, reproduction, and transmittal of classified information within the Department to provide protection for such information and to prevent access by unauthorized...
-
Code of Federal Regulations, 2010 CFR
2010-04-01
... Relations DEPARTMENT OF STATE GENERAL SECURITY INFORMATION REGULATIONS § 9.13 Safeguarding. Specific controls on the use, processing, storage, reproduction, and transmittal of classified information within the Department to provide protection for such information and to prevent access by unauthorized...
-
Safeguards-by-Design: Guidance for Independent Spent Fuel Dry Storage Installations (ISFSI)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Trond Bjornard; Philip C. Durst
2012-05-01
This document summarizes the requirements and best practices for implementing international nuclear safeguards at independent spent fuel storage installations (ISFSIs), also known as Away-from- Reactor (AFR) storage facilities. These installations may provide wet or dry storage of spent fuel, although the safeguards guidance herein focuses on dry storage facilities. In principle, the safeguards guidance applies to both wet and dry storage. The reason for focusing on dry independent spent fuel storage installations is that this is one of the fastest growing nuclear installations worldwide. Independent spent fuel storage installations are typically outside of the safeguards nuclear material balance area (MBA)more » of the reactor. They may be located on the reactor site, but are generally considered by the International Atomic Energy Agency (IAEA) and the State Regulator/SSAC to be a separate facility. The need for this guidance is becoming increasingly urgent as more and more nuclear power plants move their spent fuel from resident spent fuel ponds to independent spent fuel storage installations. The safeguards requirements and best practices described herein are also relevant to the design and construction of regional independent spent fuel storage installations that nuclear power plant operators are starting to consider in the absence of a national long-term geological spent fuel repository. The following document has been prepared in support of two of the three foundational pillars for implementing Safeguards-by-Design (SBD). These are: i) defining the relevant safeguards requirements, and ii) defining the best practices for meeting the requirements. This document was prepared with the design of the latest independent dry spent fuel storage installations in mind and was prepared specifically as an aid for designers of commercial nuclear facilities to help them understand the relevant international requirements that follow from a country’s safeguards agreement
-
Changing Landscapes in Safeguarding Babies and Young Children in England
ERIC Educational Resources Information Center
Lumsden, Eunice
2014-01-01
The importance of safeguarding children from violence is internationally recognised. However, detecting, intervening and protecting children from abuse both within the family and in institutions is complex. This paper specifically focuses on safeguarding in England and how workforce reform in the early years offers the opportunity to forge new…
-
Furfural and hydroxymethylfurfural tolerance in Escherichia coli ΔacrR regulatory mutants.
Luhe, Annette Lin; Lim, Chan Yuen; Gerken, Henri; Wu, Jinchuan; Zhao, Hua
2015-01-01
The presence of the highly toxic furfural and hydroxymethylfurfural (HMF) in the hydrolysate of lignocellulosic biomass prompted the investigation of the Escherichia coli ΔacrR regulatory mutant for higher tolerance to these compounds, to facilitate the production of biofuels and biochemicals, and further biocatalytic conversions. In comparison with the parental strain, the regulatory mutant with the upregulated efflux pump AcrAB-TolC produced moderately better growth and higher tolerance to concentrations of furfural and HMF between 1 and 2 g L(-1) . © 2014 International Union of Biochemistry and Molecular Biology, Inc.
-
Long-term proliferation and safeguards issues in future technologies
DOE Office of Scientific and Technical Information (OSTI.GOV)
Keisch, B.; Auerbach, C.; Fainberg, A.
1986-02-01
The purpose of the task was to assess the effect of potential new technologies, nuclear and non-nuclear, on safeguards needs and non-proliferation policies, and to explore possible solutions to some of the problems envisaged. Eight subdivisions were considered: New Enrichment Technologies; Non-Aqueous Reprocessing Technologies; Fusion; Accelerator-Driven Reactor Systems; New Reactor Types; Heavy Water and Deuterium; Long-Term Storage of Spent Fuel; and Other Future Technologies (Non-Nuclear). For each of these subdivisions, a careful review of the current world-wide effort in the field provided a means of subjectively estimating the viability and qualitative probability of fruition of promising technologies. Technologies for whichmore » safeguards and non-proliferation requirements have been thoroughly considered by others were not restudied here (e.g., the Fast Breeder Reactor). The time scale considered was 5 to 40 years for possible initial demonstration although, in some cases, a somewhat optimistic viewpoint was embraced. Conventional nuclear-material safeguards are only part of the overall non-proliferation regime. Other aspects are international agreements, export controls on sensitive technologies, classification of information, intelligence gathering, and diplomatic initiatives. The focus here is on safeguards, export controls, and classification.« less
-
Mazzariol, A; Tokue, Y; Kanegawa, T M; Cornaglia, G; Nikaido, H
2000-12-01
Immunoblotting with antibody against AcrA, an obligatory component of the AcrAB multidrug efflux system, showed that this protein was overexpressed by >/=170% in 9 of 10 clinical isolates of Esherichia coli with high-level ciprofloxacin resistance (MICs, >/=32 microg/ml) but not in any of the 15 isolates for which the MIC was
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Davis, G.; Mansur, D.L.; Ruhter, W.D.
1994-01-01
The Lawrence Livermore National Laboratory (LLNL) carries out safeguards and security activities for the Department of Energy (DOE), Office of Safeguards and Security (OSS), as well as other organizations, both within and outside the DOE. This document summarizes the activities conducted for the OSS during the first quarter of fiscal year 1994 (October through December, 1993). The nature and scope of the activities carried out for OSS at LLNL require a broad base of technical expertise. To assure projects are staffed and executed effectively, projects are conducted by the organization at LLNL best able to supply the needed technical expertise.more » These projects are developed and managed by senior program managers. Institutional oversight and coordination is provided through the LLNL Deputy Director`s office. At present, the Laboratory is supporting OSS in five areas: (1) Safeguards Technology, (2) Safeguards and Decision Support, (3) Computer Security, (4) DOE Automated Physical Security, and (5) DOE Automated Visitor Access Control System. This report describes the activities in each of these five areas. The information provided includes an introduction which briefly describes the activity, summary of major accomplishments, task descriptions with quarterly progress, summaries of milestones and deliverables and publications published this quarter.« less
-
Abdali, Narges; Parks, Jerry M.; Haynes, Keith M.; ...
2016-10-21
Antibiotic resistance is a major threat to human welfare. Inhibitors of multidrug efflux pumps (EPIs) are promising alternative therapeutics that could revive activities of antibiotics and reduce bacterial virulence. Identification of new druggable sites for inhibition is critical for developing effective EPIs, especially in light of constantly emerging resistance. We describe new EPIs that interact with and possibly inhibit the function of periplasmic membrane fusion proteins, critical components of efflux pumps that are responsible for the activation of the transporter and the recruitment of the outer-membrane channel. The discovered EPIs bind to AcrA, a component of the prototypical AcrAB-TolC pump,more » change its structure in vivo, inhibit efflux of fluorescent probes and potentiate the activities of antibiotics in Escherichia coli cells. These findings expand the chemical and mechanistic diversity of EPIs, suggest the mechanism for regulation of the efflux pump assembly and activity, and provide a promising path for reviving the activities of antibiotics in resistant bacteria.« less
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Abdali, Narges; Parks, Jerry M.; Haynes, Keith M.
Antibiotic resistance is a major threat to human welfare. Inhibitors of multidrug efflux pumps (EPIs) are promising alternative therapeutics that could revive activities of antibiotics and reduce bacterial virulence. Identification of new druggable sites for inhibition is critical for developing effective EPIs, especially in light of constantly emerging resistance. We describe new EPIs that interact with and possibly inhibit the function of periplasmic membrane fusion proteins, critical components of efflux pumps that are responsible for the activation of the transporter and the recruitment of the outer-membrane channel. The discovered EPIs bind to AcrA, a component of the prototypical AcrAB-TolC pump,more » change its structure in vivo, inhibit efflux of fluorescent probes and potentiate the activities of antibiotics in Escherichia coli cells. These findings expand the chemical and mechanistic diversity of EPIs, suggest the mechanism for regulation of the efflux pump assembly and activity, and provide a promising path for reviving the activities of antibiotics in resistant bacteria.« less
-
Code of Federal Regulations, 2014 CFR
2014-01-01
... first file applications with the committee to ship such onions; (2) Handlers shall obtain inspection... AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE ONIONS GROWN IN CERTAIN DESIGNATED...) The committee, with the approval of the Secretary, may prescribe adequate safeguards to prevent onions...
-
Code of Federal Regulations, 2013 CFR
2013-01-01
... first file applications with the committee to ship such onions; (2) Handlers shall obtain inspection... AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE ONIONS GROWN IN CERTAIN DESIGNATED...) The committee, with the approval of the Secretary, may prescribe adequate safeguards to prevent onions...
-
Code of Federal Regulations, 2012 CFR
2012-01-01
... first file applications with the committee to ship such onions; (2) Handlers shall obtain inspection... and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE ONIONS GROWN IN CERTAIN DESIGNATED...) The committee, with the approval of the Secretary, may prescribe adequate safeguards to prevent onions...
-
Code of Federal Regulations, 2011 CFR
2011-01-01
... first file applications with the committee to ship such onions; (2) Handlers shall obtain inspection... and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE ONIONS GROWN IN CERTAIN DESIGNATED...) The committee, with the approval of the Secretary, may prescribe adequate safeguards to prevent onions...
-
14 CFR 1212.605 - Safeguarding information in systems of records.
Code of Federal Regulations, 2010 CFR
2010-01-01
... requirements applicable to the system of records. (c) When records or copies of records are distributed to... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Safeguarding information in systems of... systems of records. (a) Safeguards appropriate for a NASA system of records shall be developed by the...
-
The Role of School Psychologists in Child Protection and Safeguarding
ERIC Educational Resources Information Center
Woods, Kevin; Bond, Caroline; Tyldesley, Kath; Farrell, Peter; Humphrey, Neil
2011-01-01
Child protection and safeguarding are important aspects of work for all professionals working with children. The current article outlines the international context of school psychologists' work in relation to child protection and safeguarding and describes the United Kingdom context in more detail. Given the relatively recent broadening of the UK…
-
Investigating staff knowledge of safeguarding and pressure ulcers in care homes.
Ousey, K; Kaye, V; McCormick, K; Stephenson, J
2016-01-01
To investigate whether nursing/care home staff regard pressure ulceration as a safeguarding issue; and to explore reporting mechanisms for pressure ulcers (PUs) in nursing/care homes. Within one clinical commissioning group, 65 staff members from 50 homes completed a questionnaire assessing their experiences of avoidable and unavoidable PUs, grading systems, and systems in place for referral to safeguarding teams. Understanding of safeguarding was assessed in depth by interviews with 11 staff members. Staff observed an average of 2.72 PUs in their workplaces over the previous 12 months, judging 45.6% to be avoidable. Only a minority of respondents reported knowledge of a grading system (mostly the EPUAP/NPUAP system). Most respondents would refer PUs to the safeguarding team: the existence of a grading system, or guidance, appeared to increase that likelihood. Safeguarding was considered a priority in most homes; interviewees were familiar with the term safeguarding, but some confusion over its meaning was apparent. Quality of written documentation and verbal communication received before residents returned from hospital was highlighted. However, respondents expressed concern over lack of information regarding skin integrity. Most staff had received education regarding ulcer prevention or wound management during training, but none reported post-registration training or formal education programmes; reliance was placed on advice of district nurses or tissue viability specialists. Staff within nursing/care homes understand the fundamentals of managing skin integrity and the importance of reporting skin damage; however, national education programmes are needed to develop knowledge and skills to promote patient health-related quality of life, and to reduce the health-care costs of pressure damage. Further research to investigate understanding, knowledge and skills of nursing/care home staff concerning pressure ulcer development and safeguarding will become increasingly
-
Simulation Enabled Safeguards Assessment Methodology
DOE Office of Scientific and Technical Information (OSTI.GOV)
Robert Bean; Trond Bjornard; Thomas Larson
2007-09-01
It is expected that nuclear energy will be a significant component of future supplies. New facilities, operating under a strengthened international nonproliferation regime will be needed. There is good reason to believe virtual engineering applied to the facility design, as well as to the safeguards system design will reduce total project cost and improve efficiency in the design cycle. Simulation Enabled Safeguards Assessment MEthodology (SESAME) has been developed as a software package to provide this capability for nuclear reprocessing facilities. The software architecture is specifically designed for distributed computing, collaborative design efforts, and modular construction to allow step improvements inmore » functionality. Drag and drop wireframe construction allows the user to select the desired components from a component warehouse, render the system for 3D visualization, and, linked to a set of physics libraries and/or computational codes, conduct process evaluations of the system they have designed.« less
-
Menezes, Regina Andrade; Pimentel, Catarina; Silva, Ana Rita Courelas; Amaral, Catarina; Merhej, Jawad; Devaux, Frédéric; Rodrigues-Pousada, Claudina
2017-04-01
Response to arsenic stress in Saccharomyces cerevisiae is orchestrated by the regulatory protein Yap8, which mediates transcriptional activation of ACR2 and ACR3. This study contributes to the state of art knowledge of the molecular mechanisms underlying yeast stress response to arsenate as it provides the genetic and biochemical evidences that Yap8, through cysteine residues 132, 137, and 274, is the sensor of presence of arsenate in the cytosol. Moreover, it is here reported for the first time the essential role of the Mediator complex in the transcriptional activation of ACR2 by Yap8. Based on our data, we propose an order-of-function map to recapitulate the sequence of events taking place in cells injured with arsenate. Modification of the sulfhydryl state of these cysteines converts Yap8 in its activated form, triggering the recruitment of the Mediator complex to the ACR2/ACR3 promoter, through the interaction with the tail subunit Med2. The Mediator complex then transfers the regulatory signals conveyed by Yap8 to the core transcriptional machinery, which culminates with TBP occupancy, ACR2 upregulation and cell adaptation to arsenate stress. Additional co-factors are required for the transcriptional activation of ACR2 by Yap8, particularly the nucleosome remodeling activity of SWI/SNF and SAGA complexes. Copyright © 2017. Published by Elsevier B.V.
-
6. View northeast of Ten Acre Lot with Joseph Fry ...
6. View northeast of Ten Acre Lot with Joseph Fry Farm complex (center) and Beehive House (right)in the background - Joseph Fry Farm Landscape, 2153 South County Trail Road (U.S. Route 2), East Greenwich, Kent County, RI
-
SARS: Safeguards Accounting and Reporting Software
NASA Astrophysics Data System (ADS)
Mohammedi, B.; Saadi, S.; Ait-Mohamed, S.
In order to satisfy the requirements of the SSAC (State System for Accounting and Control of nuclear materials), for recording and reporting objectives; this computer program comes to bridge the gape between nuclear facilities operators and national inspection verifying records and delivering reports. The SARS maintains and generates at-facility safeguards accounting records and generates International Atomic Energy Agency (IAEA) safeguards reports based on accounting data input by the user at any nuclear facility. A database structure is built and BORLAND DELPHI programming language has been used. The software is designed to be user-friendly, to make extensive and flexible management of menus and graphs. SARS functions include basic physical inventory tacking, transaction histories and reporting. Access controls are made by different passwords.
-
10 CFR 76.39 - Public meeting.
Code of Federal Regulations, 2010 CFR
2010-01-01
..., unless otherwise specified by the Director. (3) A public meeting will be open to all interested members... Data, Classified National Security Information, Unclassified Controlled Nuclear Information, Safeguards Information, Proprietary Data, or other withholdable information may be introduced at the meeting. [59 FR...
-
10 CFR 76.39 - Public meeting.
Code of Federal Regulations, 2011 CFR
2011-01-01
..., unless otherwise specified by the Director. (3) A public meeting will be open to all interested members... Data, Classified National Security Information, Unclassified Controlled Nuclear Information, Safeguards Information, Proprietary Data, or other withholdable information may be introduced at the meeting. [59 FR...
-
19 CFR 206.65 - Public hearing.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 19 Customs Duties 3 2013-04-01 2013-04-01 false Public hearing. 206.65 Section 206.65 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF...
-
19 CFR 206.65 - Public hearing.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 19 Customs Duties 3 2014-04-01 2014-04-01 false Public hearing. 206.65 Section 206.65 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF...
-
19 CFR 206.65 - Public hearing.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 19 Customs Duties 3 2010-04-01 2010-04-01 false Public hearing. 206.65 Section 206.65 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF...
-
78 FR 37849 - Advisory Committee on Reactor Safeguards; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-24
... teleconferencing link. The availability of video teleconferencing services is not guaranteed. Dated: June 18, 2013... participation in ACRS meetings were published in the Federal Register on October 18, 2012, (76 FR 64146-64147.../ . Video teleconferencing service is available for observing open sessions of ACRS meetings. Those wishing...
-
78 FR 65009 - Advisory Committee On Reactor Safeguards; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-30
... of and participation in ACRS meetings were published in the Federal Register on October 18, 2012, (77... http://www.nrc.gov/reading-rm/doc-collections/ACRS/ . Video teleconferencing service is available for... facilities that they use to establish the video teleconferencing link. The availability of video...
-
78 FR 53485 - Advisory Committee on Reactor Safeguards; Notice of Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-29
... of and participation in ACRS meetings were published in the Federal Register on October 18, 2012, (77... http://www.nrc.gov/reading-rm/doc-collections/ACRS/ . Video teleconferencing service is available for... facilities that they use to establish the video teleconferencing link. The availability of video...
-
Informational privacy and the public's health: the Model State Public Health Privacy Act.
Gostin, L O; Hodge, J G; Valdiserri, R O
2001-09-01
Protecting public health requires the acquisition, use, and storage of extensive health-related information about individuals. The electronic accumulation and exchange of personal data promises significant public health benefits but also threatens individual privacy; breaches of privacy can lead to individual discrimination in employment, insurance, and government programs. Individuals concerned about privacy invasions may avoid clinical or public health tests, treatments, or research. Although individual privacy protections are critical, comprehensive federal privacy protections do not adequately protect public health data, and existing state privacy laws are inconsistent and fragmented. The Model State Public Health Privacy Act provides strong privacy safeguards for public health data while preserving the ability of state and local public health departments to act for the common good.
-
Patsios, Demi; Carpenter, John
2010-01-01
Background Joint training for interagency working is carried out by Local Safeguarding Children Boards in England to promote effective local working to safeguard and promote the welfare of children. Purpose This paper reports on the findings of the outputs and outcomes of interagency training to safeguard children in eight Local Safeguarding Children Boards. Methods A review of Local Safeguarding Children Board documentation, observations of Local Safeguarding Children Board training sub-group meetings and a series of interviews with training key stakeholders in each Local Safeguarding Children Board were used to assess how partner agencies in the Local Safeguarding Children Boards carried out their statutory responsibilities to organise interagency training. ‘Realistic Evaluation’ was used to evaluate the mechanisms by which a central government mandate produced particular inter-agency training outputs (number of courses, training days) and joint working outcomes (effective partnerships), within particular Local Safeguarding Children Board contexts. Results The ‘mandated partnership’ imposed on Local Safeguarding Children Boards by central government left little choice but for partner agencies to work together to deliver joint training, which in turn affected the dynamics of working partnerships across the various sites. The effectiveness of the training sub group determined the success of the organisation and delivery of training for joint working. Despite having a central mandate, Local Safeguarding Children Boards had heterogeneous funding and training arrangements. These resulted in significant variations in the outputs in terms of the number of courses per ‘children in need’ in the locality and in the cost per course. Conclusions Interagency training which takes account of the context of the Local Safeguarding Children Board is more likely to produce better trained staff, effective partnership working, and lead to better integrated safeguarding
-
Termination of Safeguards for Accountable Nuclear Materials at the Idaho National Laboratory
DOE Office of Scientific and Technical Information (OSTI.GOV)
Michael Holzemer; Alan Carvo
2012-04-01
Termination of safeguards ends requirements of Nuclear Material Control and Accountability (MC&A) and thereby removes the safeguards basis for applying physical protection requirements for theft and diversion of nuclear material, providing termination requirements are met as described. Department of Energy (DOE) M 470.4 6 (Nuclear Material Control and Accountability [8/26/05]) stipulates: 1. Section A, Chapter I (1)( q) (1): Safeguards can be terminated on nuclear materials provided the following conditions are met: (a) 'If the material is special nuclear material (SNM) or protected as SNM, it must be attractiveness level E and have a measured value.' (b) 'The material hasmore » been determined by DOE line management to be of no programmatic value to DOE.' (c) 'The material is transferred to the control of a waste management organization where the material is accounted for and protected in accordance with waste management regulations. The material must not be collocated with other accountable nuclear materials.' Requirements for safeguards termination depend on the safeguards attractiveness levels of the material. For attractiveness level E, approval has been granted from the DOE Idaho Operations Office (DOE ID) to Battelle Energy Alliance, LLC (BEA) Safeguards and Security (S&S). In some cases, it may be necessary to dispose of nuclear materials of attractiveness level D or higher. Termination of safeguards for such materials must be approved by the Departmental Element (this is the DOE Headquarters Office of Nuclear Energy) after consultation with the Office of Security.« less
-
75 FR 442 - Notice of Proposed Withdrawal Extension and Opportunity for Public Meeting; South Dakota
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-05
... (PLO) No. 6782 for an additional 20-year term. PLO No. 6782 withdrew 2,387.22 acres of National Forest... contains 2,387.22 acres in Custer County as follows: Black Hills Meridian Black Hills National Forest T. 3... withdrawal would not alter the applicability of those public land laws governing the use of National Forest...
-
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Safeguards. 958.56 Section 958.56 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... dehydrators into dehydrated onion products, from entering channels of trade for other than the purpose...
-
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Safeguards. 946.55 Section 946.55 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... channels of trade and other outlets for other than the specific purposes authorized therefor, and the...
-
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Safeguards. 966.56 Section 966.56 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... from entering channels of trade for other than the specific purpose authorized therefor, and rules...
-
The US Support Program to IAEA Safeguards Priority of Training and Human Resources
DOE Office of Scientific and Technical Information (OSTI.GOV)
Queirolo,A.
2008-06-13
The U.S. Support Program to IAEA Safeguards (USSP) priority of training and human resources is aimed at providing the Department of Safeguards with an appropriate mixture of regular staff and extrabudgetary experts who are qualified to meet the IAEA's technical needs and to provide personnel with appropriate instruction to improve the technical basis and specific skills needed to perform their job functions. The equipment and methods used in inspection activities are unique, complex, and evolving. New and experienced safeguards inspectors need timely and effective training to perform required tasks and to learn new skills prescribed by new safeguards policies ormore » agreements. The role of the inspector has changed from that of strictly an accountant to include that of a detective. New safeguards procedures are being instituted, and therefore, experienced inspectors must be educated on these new procedures. The USSP also recognizes the need for training safeguards support staff, particularly those who maintain and service safeguards equipment (SGTS), and those who perform information collection and analysis (SGIM). The USSP is committed to supporting the IAEA with training to ensure the effectiveness of all staff members and will continue to offer its assistance in the development and delivery of basic, refresher, and advanced training courses. This paper will discuss the USSP ongoing support in the area of training and IAEA staffing.« less
-
International Safeguards Technology and Policy Education and Training Pilot Programs
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dreicer, M; Anzelon, G A; Essner, J T
2009-06-16
A major focus of the National Nuclear Security Administration-led Next Generation Safeguards Initiative (NGSI) is the development of human capital to meet present and future challenges to the safeguards regime. An effective university-level education in safeguards and related disciplines is an essential element in a layered strategy to rebuild the safeguards human resource capacity. NNSA launched two pilot programs in 2008 to develop university level courses and internships in association with James, Martin Center for Nonproliferation Studies (CNS) at the Monterey Institute of International Studies (MIIS) and Texas A&M University (TAMU). These pilot efforts involved 44 students in total andmore » were closely linked to hands-on internships at Los Alamos National Laboratory (LANL) and Lawrence Livermore National Laboratory (LLNL). The Safeguards and Nuclear Material Management pilot program was a collaboration between TAMU, LANL, and LLNL. The LANL-based coursework was shared with the students undertaking internships at LLNL via video teleconferencing. A weeklong hands-on exercise was also conducted at LANL. A second pilot effort, the International Nuclear Safeguards Policy and Information Analysis pilot program was implemented at MIIS in cooperation with LLNL. Speakers from MIIS, LLNL, and other U.S. national laboratories (LANL, BNL) delivered lectures for the audience of 16 students. The majority of students were senior classmen or new master's degree graduates from MIIS specializing in nonproliferation policy studies. The two pilots programs concluded with an NGSI Summer Student Symposium, held at LLNL, where 20 students participated in LLNL facility tours and poster sessions. The value of bringing together the students from the technical and policy pilots was notable and will factor into the planning for the continued refinement of the two programs in the coming years.« less
-
10 CFR Appendix G to Part 73 - Reportable Safeguards Events
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 2 2013-01-01 2013-01-01 false Reportable Safeguards Events G Appendix G to Part 73.... G Appendix G to Part 73—Reportable Safeguards Events Pursuant to the provisions of 10 CFR 73.71 (b.... (b) Any other threatened, attempted, or committed act not previously defined in appendix G with the...
-
10 CFR Appendix G to Part 73 - Reportable Safeguards Events
Code of Federal Regulations, 2014 CFR
2014-01-01
... 10 Energy 2 2014-01-01 2014-01-01 false Reportable Safeguards Events G Appendix G to Part 73.... G Appendix G to Part 73—Reportable Safeguards Events Pursuant to the provisions of 10 CFR 73.71 (b.... (b) Any other threatened, attempted, or committed act not previously defined in appendix G with the...
-
10 CFR Appendix G to Part 73 - Reportable Safeguards Events
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 2 2011-01-01 2011-01-01 false Reportable Safeguards Events G Appendix G to Part 73.... G Appendix G to Part 73—Reportable Safeguards Events Pursuant to the provisions of 10 CFR 73.71 (b.... (b) Any other threatened, attempted, or committed act not previously defined in appendix G with the...
-
10 CFR Appendix G to Part 73 - Reportable Safeguards Events
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 2 2012-01-01 2012-01-01 false Reportable Safeguards Events G Appendix G to Part 73.... G Appendix G to Part 73—Reportable Safeguards Events Pursuant to the provisions of 10 CFR 73.71 (b.... (b) Any other threatened, attempted, or committed act not previously defined in appendix G with the...
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-11
... the remaining 27,825 acres of National Forest System lands withdrawn for the Bureau of Reclamation's...,600 acres National Forest System lands in Sublette County, Wyoming, for the Bureau of Reclamation's.... The lands will not be opened to the public land or mining laws until completion of an analysis to...
-
Taylor, Mark J.
2015-01-01
The disclosure of confidential patient data without an individual's explicit consent should be for purposes that persons have reason to both expect and accept. We do not currently have the required level of clarity or consistency in understanding regarding the disclosure of confidential patient information for public health purposes to support effective public dialogue. The Health Service (Control of Patient Information) Regulations 2002 establish a legal basis in England and Wales for data to be disclosed for public health purposes without patient consent. Under the Regulations, there is more than one potential route towards lawful processing: Data may be processed for public health purposes under both Regulations 3 and 5. The alternatives have different safeguards and conditions attached, and their respective applicability to processing for purposes of public health improvement is currently unclear and subject to review. Beyond the need for clarity regarding the safeguards applicable to processing for particular public health purposes, there are reasons to prefer recognition that Regulation 5 is the most appropriate legal basis for disclosure when the purpose is public health improvement rather than public health protection. Where health improvement, rather than protection, is the aim, there is no justification for discarding the additional safeguards associated with processing under Regulation 5. PMID:25995294
-
Assessing the effectiveness of safeguards at a medium-sized spent-fuel reprocessing facility
DOE Office of Scientific and Technical Information (OSTI.GOV)
Higinbotham, W.; Fishbone, L.G.; Suda, S.
1983-01-01
In order to evaluate carefully and systematically the effectiveness of safeguards at nuclear-fuel-cycle facilities, the International Atomic Energy Agency has adopted a safeguards effectiveness assessment methodology. The methodology has been applied to a well-characterized, medium-sized, spent-fuel reprocessing plant to understand how explicit safeguards inspection procedures would serve to expose conceivable nuclear materials diversion schemes, should such diversion occur.
-
17 CFR 160.30 - Procedures to safeguard customer records and information.
Code of Federal Regulations, 2010 CFR
2010-04-01
... customer records and information. 160.30 Section 160.30 Commodity and Securities Exchanges COMMODITY... Date § 160.30 Procedures to safeguard customer records and information. Every futures commission... physical safeguards for the protection of customer records and information. These policies and procedures...
-
Nuclear safeguards in Brazil and Argentina: 25 years of ABACC
NASA Astrophysics Data System (ADS)
Kassenova, Togzhan
2017-11-01
As possessors of advanced nuclear technology, Brazil and Argentina bear special responsibility for helping the international community and neighbors in their region feel confident that their nuclear programs are peaceful, secure, and safe. Over the past 25 years, the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials (ABACC) has played an indispensable role in strengthening such confidence by implementing nuclear safeguards in the two countries. Today, ABACC carries out safeguards inspections at a total of 76 nuclear facilities in Brazil and Argentina. This article describes how Brazil and Argentina view trends in the global nonproliferation regime and international nuclear safeguards, and explains how these trends relate to unique challenges and opportunities facing Brazil, Argentina, and ABACC.
-
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Safeguards. 945.56 Section 945.56 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... prevent shipments pursuant to § 945.53 from entering channels of trade and other outlets for other than...
-
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Safeguards. 948.24 Section 948.24 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... entering trade channels other than those authorized by regulations and by such rules as may be necessary...
-
19 CFR 206.5 - Public hearing.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 19 Customs Duties 3 2013-04-01 2013-04-01 false Public hearing. 206.5 Section 206.5 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS...
-
19 CFR 206.5 - Public hearing.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 19 Customs Duties 3 2014-04-01 2014-04-01 false Public hearing. 206.5 Section 206.5 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS...
-
19 CFR 206.5 - Public hearing.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 19 Customs Duties 3 2010-04-01 2010-04-01 false Public hearing. 206.5 Section 206.5 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW OF RELIEF ACTIONS...
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Davis, G.; Mansur, D.L.; Ruhter, W.D.
The Lawrence Livermore National Laboratory (LLNL) carries out safeguards and security activities for the Department of Energy (DOE), Office of Safeguards and Security (OSS), as well as other organizations, both within and outside the DOE. This document summarizes the activities conducted for the OSS during the First Quarter of Fiscal Year 1997 (October through December, 1996). The nature and scope of the activities carried out for OSS at LLNL require a broad base of technical expertise. To assure projects are staffed and executed effectively, projects are conducted by the organization at LLNL best able to supply the needed technical expertise.more » These projects are developed and managed by senior program managers. Institutional oversight and coordination is provided through the LLNL Deputy Director`s office. At present, the Laboratory is supporting OSS in four areas: (1) safeguards technology; (2) safeguards and material accountability; (3) computer security--distributed systems; and (4) physical and personnel security support. The remainder of this report describes the activities in each of these four areas. The information provided includes an introduction which briefly describes the activity, summary of major accomplishments, task descriptions with quarterly progress, summaries of milestones and deliverables and publications published this quarter.« less
-
Machine safety: proper safeguarding techniques.
Martin, K J
1992-06-01
1. OSHA mandates certain safeguarding of machinery to prevent accidents and protect machine operators. OSHA specifies moving parts that must be guarded and sets criteria for the guards. 2. A 1989 OSHA standard for lockout/tagout requires locking the energy source during maintenance, periodically inspecting for power transmission, and training maintenance workers. 3. In an amputation emergency, first aid for cardiopulmonary resuscitation, shock, and bleeding are the first considerations. The amputated part should be wrapped in moist gauze, placed in a sealed plastic bag, and placed in a container of 50% water and 50% ice for transport. 4. The role of the occupational health nurse in machine safety is to conduct worksite analyses to identify proper safeguarding and to communicate deficiencies to appropriate personnel; to train workers in safe work practices and observe compliance in the use of machine guards; to provide care to workers injured by machines; and to reinforce safe work practices among machine operators.
-
Safeguarding and Protecting Children in Maternity Services: Implications for Practice
ERIC Educational Resources Information Center
Lazenbatt, Anne; Greer, Jean
2009-01-01
This article debates the issues involved in safeguarding and protecting children in maternity services and offers implications for professional practice. Midwives and other staff who work as members of the maternity team have a safeguarding role to play in the identification of babies and children who have been abused, or are at risk of abuse, and…
-
Joven, Beatriz E; Escribano, Pilar; Andreu, Jose Luis; Loza, Estibaliz; Jimenez, Carmen; de Yebenes, M Jesus Garcia; Ruiz-Cano, M Jose; Carmona, Loreto; Carreira, Patricia E
2018-06-01
To analyze the performance of the 1980 ACR and new 2013 ACR/EULAR criteria for systemic sclerosis (SSc) in cutaneous SSc (lcSSc) patients, especially those affected by lcSSc and pulmonary arterial hypertension (PAH). All patients with a clinical lcSSc diagnosis from a prospective observational SSc cohort were included. Sociodemographic and disease-related variables were collected, and PAH confirmed by right heart catheterization (RHC). Performance of the 2013 and 1980 SSc criteria was analyzed in terms of clinical diagnosis. Descriptive and between-group analyses were performed as to the fulfillment of criterion sets, including comparison of survival. Overall, 321 patients were included, 63% of whom fulfilled the 1980 ACR and 93% the 2013 ACR/EULAR criteria. Agreement between both criteria sets proved poor (κ = 0.23). LcSSC patients fulfilling both criterion sets were significantly younger at diagnosis, whilst presenting organ involvement, calcinosis, fingertip digital ulcers, and pitting scars more frequently than those who met the 2013 criteria only. Patients who fulfilled the 2013 but not the 1980 criteria presented a higher degree of ACA positivity and PAH. Nearly 12% of patients developed PAH. Patients who did not meet the 1980 criteria were affected by a milder disease from but demonstrated higher pulmonary vascular resistance and lower cardiac index than those fulfilling both criterion sets. Whereas patients with PAH met the 2013 criteria, only 47% fulfilled the 1980 criteria. Regardless of criterion set fulfillment, high mortality was observed in PAH patients, with no significant between-patient difference based on criterion set. The new 2013 ARC/EULAR criteria prove more accurate than the former 1980 ACR criteria in identifying and differentiating patients with lcSSc, especially those with associated PAH. Since PAH exhibits a better prognosis if treated early, all SSc patients should undergo PAH screening. Copyright © 2018 Elsevier Inc. All rights
-
Soparkar, Ketaki; Kinana, Alfred D.; Weeks, Jon W.; Morrison, Keith D.; Nikaido, Hiroshi
2015-01-01
ABSTRACT The AcrB protein of Escherichia coli, together with TolC and AcrA, forms a contiguous envelope conduit for the capture and extrusion of diverse antibiotics and cellular metabolites. In this study, we sought to expand our knowledge of AcrB by conducting genetic and functional analyses. We began with an AcrB mutant bearing an F610A substitution in the drug binding pocket and obtained second-site substitutions that overcame the antibiotic hypersusceptibility phenotype conferred by the F610A mutation. Five of the seven unique single amino acid substitutions—Y49S, V127A, V127G, D153E, and G288C—mapped in the periplasmic porter domain of AcrB, with the D153E and G288C mutations mapping near and at the distal drug binding pocket, respectively. The other two substitutions—F453C and L486W—were mapped to transmembrane (TM) helices 5 and 6, respectively. The nitrocefin efflux kinetics data suggested that all periplasmic suppressors significantly restored nitrocefin binding affinity impaired by the F610A mutation. Surprisingly, despite increasing MICs of tested antibiotics and the efflux of N-phenyl-1-naphthylamine, the TM suppressors did not improve the nitrocefin efflux kinetics. These data suggest that the periplasmic substitutions act by influencing drug binding affinities for the distal binding pocket, whereas the TM substitutions may indirectly affect the conformational dynamics of the drug binding domain. IMPORTANCE The AcrB protein and its homologues confer multidrug resistance in many important human bacterial pathogens. A greater understanding of how these efflux pump proteins function will lead to the development of effective inhibitors against them. The research presented in this paper investigates drug binding pocket mutants of AcrB through the isolation and characterization of intragenic suppressor mutations that overcome the drug susceptibility phenotype of mutations affecting the drug binding pocket. The data reveal a remarkable structure
-
75 FR 19999 - Public Land Order No. 7739; Extension of Public Land Order No. 6776; Washington
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-16
...-Wenatchee National Forest, 215 Melody Lane, Wenatchee, Washington 98801, (509) 664-9262, or Charles R. Roy... Wenatchee National Forest. The United States Forest Service will continue to manage the lands to protect.... Public Land Order No. 6776 (55 FR 14422, (1990)) that withdrew 8,950 acres of National Forest System...
-
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Safeguards. 906.44 Section 906.44 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... pursuant to § 906.41 or § 906.42 from entering channels of trade for other than the specific purpose...
-
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Safeguards. 956.66 Section 956.66 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Onions shipped, pursuant to §§ 956.63 and 956.64, from entering channels of trade for other than the...
-
14 CFR § 1212.605 - Safeguarding information in systems of records.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Safeguarding information in systems of records. § 1212.605 Section § 1212.605 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE... Technology Security Officer for electronic records maintained in automated systems. Safeguards must insure...
-
30 CFR 77.203 - Use of material or equipment overhead; safeguards.
Code of Federal Regulations, 2010 CFR
2010-07-01
...; safeguards. 77.203 Section 77.203 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS...; safeguards. Where overhead repairs are being made at surface installations and equipment or material is taken...
-
13 CFR 108.506 - Safeguarding the NMVC Company's assets/Internal controls.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Safeguarding the NMVC Company's assets/Internal controls. 108.506 Section 108.506 Business Credit and Assistance SMALL BUSINESS... safeguard your assets and monitor the reliability of your financial data, personnel, Portfolio, funds and...
-
13 CFR 108.506 - Safeguarding the NMVC Company's assets/Internal controls.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Safeguarding the NMVC Company's assets/Internal controls. 108.506 Section 108.506 Business Credit and Assistance SMALL BUSINESS... safeguard your assets and monitor the reliability of your financial data, personnel, Portfolio, funds and...
-
13 CFR 108.506 - Safeguarding the NMVC Company's assets/Internal controls.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Safeguarding the NMVC Company's assets/Internal controls. 108.506 Section 108.506 Business Credit and Assistance SMALL BUSINESS... safeguard your assets and monitor the reliability of your financial data, personnel, Portfolio, funds and...
-
13 CFR 108.506 - Safeguarding the NMVC Company's assets/Internal controls.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Safeguarding the NMVC Company's assets/Internal controls. 108.506 Section 108.506 Business Credit and Assistance SMALL BUSINESS... safeguard your assets and monitor the reliability of your financial data, personnel, Portfolio, funds and...
-
13 CFR 108.506 - Safeguarding the NMVC Company's assets/Internal controls.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Safeguarding the NMVC Company's assets/Internal controls. 108.506 Section 108.506 Business Credit and Assistance SMALL BUSINESS... safeguard your assets and monitor the reliability of your financial data, personnel, Portfolio, funds and...
-
NASA Astrophysics Data System (ADS)
Brown, I. F.
2015-12-01
Southwestern Amazonia, where Bolivia, Brazil and Peru meet, faces numerous challenges to the sustainable utilization of land and water resources as the region experiences rapid population and economic growth, expanding agriculture, transportation and energy sectors, along with frequent flooding and droughts. It is also predicted to be one of the most susceptible areas for climate change in the coming decade. The Acre River Basin, one of the few trinational basins in Amazonia, lies at the center of the Madre de Dios Region (Peru), Acre State (Brazil) and Pando Department (Bolivia) or MAP Region. It covers approximately 7,500 km2 and its inhabitants range from indigenous groups avoiding contact with industrial society to more than 60,000 dwellers of a binational urban center. The basin incorporates most the challenges facing the region and this paper discusses steps underway to address the basin's vulnerability to climate-related threats. A trinational group of professionals used GIS databases and local knowledge to classify these threats and possible societal responses. To prioritize threats and to propose responses, this group adapted a method proposed by the Queensland Climate Change Centre of Excellence of Australia to develop climate risk matrices for assessing impacts, adaptation, risk and vulnerability. The three priority climate variables were prolonged and more frequent droughts, more intense flooding, and more days with temperatures > 35oC. The final matrix proposed two areas of concentration - 1) Reduce the vulnerability of communities to hydro-meteorological extreme events and 2) Protect and restore ecosystems that maintain critical water-related resources with actions in public policy, capacity-building, and immediate activities. These results are being incorporated into the Amazon Project of the Global Environment Fund of the United Nations Environment Program, administered by the Amazon Cooperation Treaty Organization (ACTO).
-
The U.S./IAEA Workshop on Software Sustainability for Safeguards Instrumentation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pepper S. E.; .; Worrall, L.
2014-08-08
The U.S. National Nuclear Security Administration’s Next Generation Safeguards Initiative, the U.S. Department of State, and the International Atomic Energy Agency (IAEA) organized a a workshop on the subject of ”Software Sustainability for Safeguards Instrumentation.” The workshop was held at the Vienna International Centre in Vienna, Austria, May 6-8, 2014. The workshop participants included software and hardware experts from national laboratories, industry, government, and IAEA member states who were specially selected by the workshop organizers based on their experience with software that is developed for the control and operation of safeguards instrumentation. The workshop included presentations, to orient the participantsmore » to the IAEA Department of Safeguards software activities related to instrumentation data collection and processing, and case studies that were designed to inspire discussion of software development, use, maintenance, and upgrades in breakout sessions and to result in recommendations for effective software practices and management. This report summarizes the results of the workshop.« less
-
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-14
... Public Lands in Clark County, NV AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Realty... sale and mineral conveyance regulations. The proposed sale also includes one 5-acre parcel in Clark... described contains 1.25 acres, more or less, in Clark County. The map delineating the proposed sale parcel...
-
"Forty Acres and a Mule" as a Pedagogical Motif
ERIC Educational Resources Information Center
Burch, Kerry
2008-01-01
This essay revisits an iconic yet now languishing phrase in United States political culture--"Forty Acres and a Mule"--to clarify the meaning of freedom and to assess the contemporary meaning of its betrayal by the U.S. government immediately after the Civil War. Among the few citizens for whom the phrase still retains a semblance of…
-
Evolution of Safeguards over Time: Past, Present, and Projected Facilities, Material, and Budget
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kollar, Lenka; Mathews, Caroline E.
This study examines the past trends and evolution of safeguards over time and projects growth through 2030. The report documents the amount of nuclear material and facilities under safeguards from 1970 until present, along with the corresponding budget. Estimates for the future amount of facilities and material under safeguards are made according to non-nuclear-weapons states’ (NNWS) plans to build more nuclear capacity and sustain current nuclear infrastructure. Since nuclear energy is seen as a clean and economic option for base load electric power, many countries are seeking to either expand their current nuclear infrastructure, or introduce nuclear power. In ordermore » to feed new nuclear power plants and sustain existing ones, more nuclear facilities will need to be built, and thus more nuclear material will be introduced into the safeguards system. The projections in this study conclude that a zero real growth scenario for the IAEA safeguards budget will result in large resource gaps in the near future.« less
-
Safeguards for healthy volunteers in drug studies.
Smith, R N
1975-09-06
Safeguards for healthy volunteers in drug studies have not been as strict as those involving patients. The shortcomings include the lack of surveillance over the scientific validity of the protocol and its ethical review, and over the financial inducements to volunteers. Recruitment is open to abuse because the volunteers may have some allegiance to the investigators. There is an urgent need to institute checks on these aspects. Most important, however, is the lack of legal safeguards for volunteers taking part in research done outside the pharmaceutical industry. The suggested procedure for obtaining consent, for health checks, and for providing compensation can be equitable to all concerned, and yet not restrict initiative, nor curtail research aims.
-
Lana, Raquel Martins; Gomes, Marcelo Ferreira da Costa; Lima, Tiago França Melo de; Honório, Nildimar Alves; Codeço, Cláudia Torres
2017-11-01
Human mobility, presence and passive transportation of Aedes aegypti mosquito, and environmental characteristics are a group of factors which contribute to the success of dengue spread and establishment. To understand this process, we assess data from dengue national and municipal basins regarding population and demographics, transportation network, human mobility, and Ae. aegypti monitoring for the Brazilian state of Acre since the first recorded dengue case in the year 2000 to the year 2015. During this period, several changes in Acre's transport infrastructure and urbanization have been started. To reconstruct the process of dengue introduction in Acre, we propose an analytic framework based on concepts used in malaria literature, namely vulnerability and receptivity, to inform risk assessments in dengue-free regions as well as network theory concepts for disease invasion and propagation. We calculate the probability of dengue importation to Acre from other Brazilian states, the evolution of dengue spread between Acrean municipalities and dengue establishment in the state. Our findings suggest that the landscape changes associated with human mobility have created favorable conditions for the establishment of dengue virus transmission in Acre. The revitalization of its major roads, as well as the increased accessibility by air to and within the state, have increased dengue vulnerability. Unplanned urbanization and population growth, as observed in Acre during the period of study, contribute to ideal conditions for Ae. aegypti mosquito establishment, increase the difficulty in mosquito control and consequently its local receptivity.
-
The Use of Performance Metrics for the Assessment of Safeguards Effectiveness at the State Level
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bachner K. M.; George Anzelon, Lawrence Livermore National Laboratory, Livermore, CA Yana Feldman, Lawrence Livermore National Laboratory, Livermore, CA Mark Goodman,Department of State, Washington, DC Dunbar Lockwood, National Nuclear Security Administration, Washington, DC Jonathan B. Sanborn, JBS Consulting, LLC, Arlington, VA.
In the ongoing evolution of International Atomic Energy Agency (IAEA) safeguards at the state level, many safeguards implementation principles have been emphasized: effectiveness, efficiency, non-discrimination, transparency, focus on sensitive materials, centrality of material accountancy for detecting diversion, independence, objectivity, and grounding in technical considerations, among others. These principles are subject to differing interpretations and prioritizations and sometimes conflict. This paper is an attempt to develop metrics and address some of the potential tradeoffs inherent in choices about how various safeguards policy principles are implemented. The paper carefully defines effective safeguards, including in the context of safeguards approaches that take accountmore » of the range of state-specific factors described by the IAEA Secretariat and taken note of by the Board in September 2014, and (2) makes use of performance metrics to help document, and to make transparent, how safeguards implementation would meet such effectiveness requirements.« less
-
Amoco unit acquires two blocks covering 2. 7 million acres in Poland
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1992-10-12
This paper reports that an Amoco Production Co. unit has signed the first agreement by a western company for conventional petroleum exploration rights in Poland. The agreement between Amoco Poland Ltd. and Poland's Ministry of Environmental Protection, Natural Resources, and Forestry calls for Amoco to make an initial $20 million investment to conduct seismic surveys and drill wildcats on two blocks. Block A is a 1,695,750 acre spread southwest of Warsaw in the heart of the Polish trough. Block B covers about 979,000 acres southeast of Lublin on the Polish-Ukrainian border. The state has an option to acquire as muchmore » as 30% interest in future hydrocarbon development.« less
-
Gordillo, S; Guirado, E; Gil, O; Díaz, J; Amat, I; Molinos, S; Vilaplana, C; Ausina, V; Cardona, P-J
2006-07-01
Real-time RT-PCR was used to quantify the expression of genes possibly involved in Mycobacterium tuberculosis latency in in vitro and murine models. Exponential and stationary phase (EP and SP) bacilli were exposed to decreasing pH levels (from 6.5 to 4.5) in an unstirred culture, and mRNA levels for 16S rRNA, sigma factors sigA,B,E,F,G,H and M, Rv0834c, icl, nirA, narG, fpbB, acr, rpoA, recA and cysH were quantified. The expression of acr was the one that best correlated with the CFU decrease observed in SP bacilli. In the murine model, the expressions of icl, acr and sigF tended to decrease when bacillary counts increased and vice versa. Values from immunodepressed mice (e.g. alpha/beta T cells, TNF, IFN-gamma and iNOs knock out strains), with accelerated bacillary growth rate, confirmed this fact. Finally, the expression of acr was maintained in mice following long-term treatment with antibiotics. The quantification of acr expression could be useful for monitoring the presence of latent bacilli in some murine models of tuberculosis.
-
Long-Term Information Management (LTIM) of Safeguards Data at Repositories: Phase II
DOE Office of Scientific and Technical Information (OSTI.GOV)
Haddal, Risa N.
One of the challenges of implementing safeguards for geological repositories will be the long-term preservation of safeguards-related data for 100 years or more. While most countries considering the construction and operation of such facilities agree that safeguards information should be preserved, there are gaps with respect to standardized requirements, guidelines, timescales, and approaches. This study analyzes those gaps and explores research to clarify stakeholder needs, identify current policies, approaches, best practices and international standards, and explores existing safeguards information management infrastructure. The study also attempts to clarify what a safeguards data classification system might look like, how long data shouldmore » be retained, and how information should be exchanged between stakeholders at different phases of a repository’s life cycle. The analysis produced a variety of recommendations on what information to preserve, how to preserve it, where to store it, retention options and how to exchange information in the long term. Key findings include the use of the globally recognized international records management standard, ISO15489, for guidance on the development of information management systems, and the development of a Key Information File (KIF). The KIF could be used to identify only the most relevant, high-level safeguards information and the history of decision making about the repository. The study also suggests implementing on-site and off-site records storage in digital and physical form; developing a safeguards data classification system; long-term records retention with periodic reviews every 5 to 10 years during each phase of the repository life cycle; and establishing transition procedures well in advance so that data shepherds and records officers can transfer information with incoming facility managers effectively and efficiently. These and other recommendations are further analyzed in this study.« less
-
Usui, Chie; Hatta, Kotaro; Aratani, Satoko; Yagishita, Naoko; Nishioka, Kenya; Kanazawa, Teruhisa; Itoh, Kenji; Yamano, Yoshihisa; Nakamura, Hiroyuki; Nakajima, Toshihiro; Nishioka, Kusuki
2013-09-01
The aim of this study is to investigate the reliability and validity of the Japanese version of the modified American College of Rheumatology (ACR) Preliminary Diagnostic Criteria for Fibromyalgia (mACR 2010-J) and the Fibromyalgia Symptom Scale (mFS-J). According to the ACR 1990 classification criteria, patients with chronic pain were divided into the fibromyalgia group and nonfibromyalgia group (rheumatoid arthritis and osteoarthritis). Patients in both groups were assessed using mACR 2010-J and mFS-J. 294 of 462 (64 %) patients in the fibromyalgia group met mACR 2010-J, whereas 4 % (9/231) of the nonfibromyalgia group did, with sensitivity of 64 %, specificity of 96 %, positive predictive value of 97 %, negative predictive value of 56 %, and positive likelihood ratio of 16.3. Mean total scores on mFS-J significantly differentiated the fibromyalgia from the nonfibromyalgia group. According to the value of the Youden index, the best cutoff score for the mFS-J was 9/10. Our findings indicate that mACR 2010-J as a positive test and mFS-J as a quantification scale might be suitable for assessing fibromyalgia among Japanese chronic pain populations.
-
DOE Office of Scientific and Technical Information (OSTI.GOV)
Moran, B.; Stern, W.; Colley, J.
International Atomic Energy Agency (IAEA) safeguards involves verification activities at a wide range of facilities in a variety of operational phases (e.g., under construction, start-up, operating, shutdown, closed-down, and decommissioned). Safeguards optimization for each different facility type and operational phase is essential for the effectiveness of safeguards implementation. The IAEA’s current guidance regarding safeguards for the different facility types in the various lifecycle phases is provided in its Design Information Examination (DIE) and Verification (DIV) procedure. 1 Greater efficiency in safeguarding facilities that are shut down or closed down, including those being decommissioned, could allow the IAEA to use amore » greater portion of its effort to conduct other verification activities. Consequently, the National Nuclear Security Administration’s Office of International Nuclear Safeguards sponsored this study to evaluate whether there is an opportunity to optimize safeguards approaches for facilities that are shutdown or closed-down. The purpose of this paper is to examine existing safeguards approaches for shutdown and closed-down facilities, including facilities being decommissioned, and to seek to identify whether they may be optimized.« less
-
30 CFR 75.1101-20 - Safeguards for dry powder chemical systems.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Safeguards for dry powder chemical systems. 75...-20 Safeguards for dry powder chemical systems. Adequate guards shall be provided along all belt conveyors in the vicinity of each dry powder chemical system to protect persons whose vision is restricted...
-
30 CFR 75.1101-20 - Safeguards for dry powder chemical systems.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Safeguards for dry powder chemical systems. 75...-20 Safeguards for dry powder chemical systems. Adequate guards shall be provided along all belt conveyors in the vicinity of each dry powder chemical system to protect persons whose vision is restricted...
-
30 CFR 75.1101-20 - Safeguards for dry powder chemical systems.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Safeguards for dry powder chemical systems. 75...-20 Safeguards for dry powder chemical systems. Adequate guards shall be provided along all belt conveyors in the vicinity of each dry powder chemical system to protect persons whose vision is restricted...
-
30 CFR 75.1101-20 - Safeguards for dry powder chemical systems.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Safeguards for dry powder chemical systems. 75...-20 Safeguards for dry powder chemical systems. Adequate guards shall be provided along all belt conveyors in the vicinity of each dry powder chemical system to protect persons whose vision is restricted...
-
76 FR 24514 - Public Land Order No. 7764; Partial Revocation of Public Land Order No. 1479; Idaho
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-02
... acres of National Forest System land withdrawn on behalf of the United States Forest Service for Priest Lake Recreation Areas within the Kaniksu National Forest. The order also opens the land to disposition.... 1714, it is ordered as follows: 1. Public Land Order No. 1479, which withdrew National Forest System...
-
Safeguards-by-Design:Guidance for High Temperature Gas Reactors (HTGRs) With Prismatic Fuel
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mark Schanfein; Casey Durst
2012-11-01
Introduction and Purpose The following is a guidance document from a series prepared for the U.S. Department of Energy (DOE) National Nuclear Security Administration (NNSA), under the Next Generation Safeguards Initiative (NGSI), to assist facility designers and operators in implementing international Safeguards-by-Design (SBD). SBD has two main objectives: (1) to avoid costly and time consuming redesign work or retrofits of new nuclear fuel cycle facilities and (2) to make the implementation of international safeguards more effective and efficient at such facilities. In the long term, the attainment of these goals would save industry and the International Atomic Energy Agency (IAEA)more » time, money, and resources and be mutually beneficial. This particular safeguards guidance document focuses on prismatic fuel high temperature gas reactors (HTGR). The purpose of the IAEA safeguards system is to provide credible assurance to the international community that nuclear material and other specified items are not diverted from peaceful nuclear uses. The safeguards system consists of the IAEA’s statutory authority to establish safeguards; safeguards rights and obligations in safeguards agreements and additional protocols; and technical measures implemented pursuant to those agreements. Of foremost importance is the international safeguards agreement between the country and the IAEA, concluded pursuant to the Treaty on the Non-Proliferation of Nuclear Weapons (NPT). According to a 1992 IAEA Board of Governors decision, countries must: notify the IAEA of a decision to construct a new nuclear facility as soon as such decision is taken; provide design information on such facilities as the designs develop; and provide detailed design information based on construction plans at least 180 days prior to the start of construction, and on "as-built" designs at least 180 days before the first receipt of nuclear material. Ultimately, the design information will be captured in an
-
Ćwiklińska, Agnieszka; Dąbrowska, Hanna; Kowalski, Robert; Kuchta, Agnieszka; Kortas-Stempak, Barbara; Fijałkowska, Aleksandra; Bednarczuk, Gabriela; Jankowski, Maciej
2018-05-11
The ratio of albumin to creatinine (ACR) is an important parameter used for detection of albuminuria in patients with early kidney damage. The aim of the study was to evaluate the harmonization of ACR results among Polish participants in an international external quality assessment (EQA) program, and to evaluate the impact of albumin and creatinine analytical performance on the harmonization of ACR results. We analyzed 182 results of albumin, 202 of creatinine, and 180 of ACR obtained from Polish laboratories in an EQA program organized by Labquality. The dispersion of the results in surveys and percentage differences between the results and target values were calculated. Moreover, differences between method groups were assessed. The inter-laboratory coefficient of variation (CV) for ACR was 36%. Only 74% of results of Polish laboratories were within the target limits; for 11% of the results, an incorrect albuminuria category would have been reported. The inter-laboratory CV for albumin was 20%, 2.6-fold higher than for creatinine. Significant differences between method groups for albumin determination have been observed, even when the same measurement technique was used. The greatest difference between two groups was 23%, 2.5-fold greater in comparison to creatinine. There is an insufficient harmonization of ACR values among Polish laboratories, caused mainly by urine albumin analytical performance. Given the important role of ACR in the classification, monitoring and treatment of kidney damage, the harmonization of albumin measurements is crucial and urgently needed.
-
Safeguards Technology Strategic Planning Pentachart
DOE Office of Scientific and Technical Information (OSTI.GOV)
Carroll, C. J.
Builds on earlier strategic planning workshops conducted for SGIT, SGTS, and SGCP. Many of recommendations from these workshops have been successfully implemented at the IAEA. Provide a context for evaluating new approaches for anticipated safeguards challenges of the future. Approach used by government and military to plan for an uncertain future. Uses consensus decision-making.
-
Far-field Wireless Energy Harvesting for Increased Safeguards Equipment Battery Life.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hymel, Ross W.
Modern unattended safeguards equipment (e.g. seals) incorporates many low-power electronic circuits, which are typically powered by expensive and toxic lithium thionyl chloride (LiSOCL2) batteries. The limited life of these batteries necessitates their periodic replacement. This replacement must be performed before total battery discharge to avoid potential loss of continuity of knowledge. Thus, the effective battery capacity becomes significantly less than the actual usable capacity. Additionally, such maintenance is a radiological hazard to personnel, as well as a monetary burden to a safeguards inspectorate. Energy harvesting, a commercially available technology, could extend the operational life of batterypowered equipment to achieve significantmore » efficiencies for safeguards deployments. Energy harvesting is the scavenging and storage of ambient energy sources, such as solar, thermal, and kinetic for use in lowpower electronic applications. While the amount of scavenged energy per unit time may be small, it most often comes from a source that will not be depleted throughout the deployment of the harvesting device. The best-known energy harvesters are solar panels and wind turbines. Recently, far-field wireless energy harvesting has become a commercially available option. Far-field wireless energy harvesting provides consistent, predictable, and un-tethered power over distances up to 50 feet. This process converts radio frequency (RF) energy, both intentionally emitted and ambient, into usable direct current (DC) power. Incorporating far-field wireless energy harvesting into safeguards equipment can significantly extend the equipment’s battery life and perhaps make it indefinite. Furthermore, additional functionality can be added to safeguards equipment without lowering its operational life expectancy. This paper explores the benefits and drawbacks of integrating far-field wireless energy harvesting into a chosen safeguards seal: the Remotely Monitored
-
77 FR 51496 - Federal Acquisition Regulation; Basic Safeguarding of Contractor Information Systems
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-24
... Federal Acquisition Regulation; Basic Safeguarding of Contractor Information Systems AGENCY: Department of... Acquisition Regulation (FAR) to add a new subpart and contract clause for the basic safeguarding of contractor... information) that will be resident on or transiting through contractor information systems. DATES: Interested...
-
Lim, Siew Ping; Nikaido, Hiroshi
2010-01-01
The multidrug efflux transporter AcrAB-TolC is known to pump out a diverse range of antibiotics, including β-lactams. However, the kinetic constants of the efflux process, needed for the quantitative understanding of resistance, were not available until those accompanying the efflux of some cephalosporins were recently determined by combining efflux with the hydrolysis of drugs by the periplasmic β-lactamase. In the present study we extended this approach to the study of a wide range of penicillins, from ampicillin and penicillin V to ureidopenicillins and isoxazolylpenicillins, by combining efflux with hydrolysis with the OXA-7 penicillinase. We found that the penicillins had a much stronger apparent affinity to AcrB and higher maximum rates of efflux than the cephalosporins. All penicillins showed strong positive cooperativity kinetics for export. The kinetic constants obtained were validated, as the MICs theoretically predicted on the basis of efflux and hydrolysis kinetics were remarkably similar to the observed MICs (except for the isoxazolylpenicillins). Surprisingly, however, the efflux kinetics of cloxacillin, for example, whose MIC decreased 512-fold in Escherichia coli upon the genetic deletion of the acrB gene, were quite similar to those of ampicillin, whose MIC decreased only 2-fold with the same treatment. Analysis of this phenomenon showed that the extensive decrease in the MIC for the acrB mutant is primarily due to the low permeation of the drug and that comparison of the MICs between the parent and the acrB strains is a very poor measure of the ability of AcrB to pump a drug out. PMID:20160052
-
10 CFR 2.809 - Participation by the Advisory Committee on Reactor Safeguards.
Code of Federal Regulations, 2010 CFR
2010-01-01
... will give its reasons for doing so. Both the ACRS recommendation and the Commission's response will be... under development by the NRC Staff, the Staff will ensure that the ACRS is given an opportunity to provide advice at appropriate stages and to identify issues to be considered during rulemaking hearings...
-
75 FR 57061 - Public Land Order No. 7749; Extension of Public Land Order Nos. 6801 and 6812; Arizona
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-17
... National Forest System lands from location or entry under the United States mining laws (30 U.S.C. chapter... Service Coronado National Forest Office, Federal Building, 300 West Congress Street, Tucson, Arizona 85701.... Public Land Order No. 6801 (55 FR 38550, (1990)) that withdrew 61.356 acres of National Forest System...
-
InfAcrOnt: calculating cross-ontology term similarities using information flow by a random walk.
Cheng, Liang; Jiang, Yue; Ju, Hong; Sun, Jie; Peng, Jiajie; Zhou, Meng; Hu, Yang
2018-01-19
Since the establishment of the first biomedical ontology Gene Ontology (GO), the number of biomedical ontology has increased dramatically. Nowadays over 300 ontologies have been built including extensively used Disease Ontology (DO) and Human Phenotype Ontology (HPO). Because of the advantage of identifying novel relationships between terms, calculating similarity between ontology terms is one of the major tasks in this research area. Though similarities between terms within each ontology have been studied with in silico methods, term similarities across different ontologies were not investigated as deeply. The latest method took advantage of gene functional interaction network (GFIN) to explore such inter-ontology similarities of terms. However, it only used gene interactions and failed to make full use of the connectivity among gene nodes of the network. In addition, all existent methods are particularly designed for GO and their performances on the extended ontology community remain unknown. We proposed a method InfAcrOnt to infer similarities between terms across ontologies utilizing the entire GFIN. InfAcrOnt builds a term-gene-gene network which comprised ontology annotations and GFIN, and acquires similarities between terms across ontologies through modeling the information flow within the network by random walk. In our benchmark experiments on sub-ontologies of GO, InfAcrOnt achieves a high average area under the receiver operating characteristic curve (AUC) (0.9322 and 0.9309) and low standard deviations (1.8746e-6 and 3.0977e-6) in both human and yeast benchmark datasets exhibiting superior performance. Meanwhile, comparisons of InfAcrOnt results and prior knowledge on pair-wise DO-HPO terms and pair-wise DO-GO terms show high correlations. The experiment results show that InfAcrOnt significantly improves the performance of inferring similarities between terms across ontologies in benchmark set.
-
Boggess, Durward Hoye; Missimer, T.M.
1975-01-01
Lehigh Acres, a residential community with a population of about 13,500 and comprising an area of about 94 square miles (243 square kilometres) in the eastern part of Lee County, has been under development since 1954. Prior to development the area was poorly drained. By 1974, more than 150 miles (241 kilometres) of drainageways had been constructed to drain the area. The water-bearing formations underlying Lehigh Acres include the water-table, sandstone, lower Hawthorn, and Suwannee aquifers. The water-table aquifer is usually not more than 30 feet (9 metres) thick; it contains water of relatively good quality, except for iron and color. Water levels in this aquifer probably have been affected by construction of drainage canals. The sandstone aquifer, used extensively throughout the area as a source of water supply usually contains water of good quality although the water is hard and in places may contain concentrations of dissolved solids and iron which exceed the recommended limits of the U.S. Public Health Service and the State of Florida for drinking water. The lower Hawthorn and Suwannee aquifers, usually encountered at depths between 440 and 850 feet (135 and 262 metres), contains water with relatively high concentrations of sodium, sulfate, chloride, and dissolved solids. Three streams, the Orange River, Hickey Creek, and Bedman Creek and the canals connected to them, provide drainage of the area. Except for the Orange River, where the water is of good chemical quality, little is known of the water quality. Similarly, little information is available on stream discharge except for the Orange River where the average annual discharge was 41.1 cubic feet per second (11.6 cubic metres per second) between 1935-46. Most lakes and ponds in Lehigh Acres are hydraulically connected to the water-table aquifer such that factors which affect one also affect the other. Theoretical drawdown curves indicate that the drainage canals may affect ground-water levels to a
-
Project Report on Development of a Safeguards Approach for Pyroprocessing
DOE Office of Scientific and Technical Information (OSTI.GOV)
Robert Bean
The Idaho National Laboratory has undertaken an effort to develop a standard safeguards approach for international commercial pyroprocessing facilities. This report details progress for the fiscal year 2010 effort. A component by component diversion pathway analysis has been performed, and has led to insight on the mitigation needs and equipment development needed for a valid safeguards approach. The effort to develop an in-hot cell detection capability led to the digital cloud chamber, and more importantly, the significant potential scientific breakthrough of the inverse spectroscopy algorithm, including the ability to identify energy and spatial location of gamma ray emitting sources withmore » a single, non-complex, stationary radiation detector system. Curium measurements were performed on historical and current samples at the FCF to attempt to determine the utility of using gross neutron counting for accountancy measurements. A solid cost estimate of equipment installation at FCF has been developed to guide proposals and cost allocations to use FCF as a test bed for safeguards measurement demonstrations. A combined MATLAB and MCNPX model has been developed to perform detector placement calculations around the electrorefiner. Early harvesting has occurred wherein the project team has been requested to provide pyroprocessing technology and safeguards short courses.« less
-
Nuclear proliferation-resistance and safeguards for future nuclear fuel cycle
NASA Astrophysics Data System (ADS)
Kuno, Y.; Inoue, N.; Senzaki, M.
2009-03-01
Corresponding to the world nuclear security concerns, future nuclear fuel cycle (NFC) should have high proliferation-resistance (PR) and physical protection (PP), while promotion of the peaceful use of the nuclear energy must not be inhibited. In order to accomplish nuclear non-proliferation from NFC, a few models of the well-PR systems should be developed so that international community can recognize them as worldwide norms. To find a good balance of 'safeguard-ability (so-called extrinsic measure or institutional barrier)' and 'impede-ability (intrinsic feature or technical barrier)' will come to be essential for NFC designers to optimize civilian nuclear technology with nuclear non-proliferation, although the advanced safeguards with high detectability can still play a dominant role for PR in the states complying with full institutional controls. Accomplishment of such goal in a good economic efficiency is a future key challenge.
-
43 CFR 2524.7 - Disposal of lands in excess of 160 acres.
Code of Federal Regulations, 2012 CFR
2012-10-01
... LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Desert-Land Entries Within a Reclamation Project § 2524.7 Disposal of lands in excess of 160 acres. Desert...
-
43 CFR 2524.7 - Disposal of lands in excess of 160 acres.
Code of Federal Regulations, 2011 CFR
2011-10-01
... LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Desert-Land Entries Within a Reclamation Project § 2524.7 Disposal of lands in excess of 160 acres. Desert...
-
43 CFR 2524.7 - Disposal of lands in excess of 160 acres.
Code of Federal Regulations, 2014 CFR
2014-10-01
... LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Desert-Land Entries Within a Reclamation Project § 2524.7 Disposal of lands in excess of 160 acres. Desert...
-
43 CFR 2524.7 - Disposal of lands in excess of 160 acres.
Code of Federal Regulations, 2013 CFR
2013-10-01
... LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Desert-Land Entries Within a Reclamation Project § 2524.7 Disposal of lands in excess of 160 acres. Desert...
-
International Atomic Energy Agency Safeguards: Challenge and response
NASA Astrophysics Data System (ADS)
Spector, Leonard S.
2017-11-01
This article provides a critical review of the nuclear accounting and inspection system of the International Atomic Energy Agency (IAEA), known as "IAEA safeguards." The article focuses on the multiple challenges the Agency confronts in verifying that all nuclear activities in the countries under its safeguards system are being pursued for exclusively peaceful purposes. The principal challenges noted are those posed by: undeclared facilities, the development of enrichment and reprocessing capabilities, illicit procurement activities, denial of inspector access, difficulties in verifying absence of weaponization activities, and difficulties in establishing that all nuclear-relevant activities in a state are peaceful. The article is in the form of annotated PowerPoint briefing slides.
-
34 CFR 300.121 - Procedural safeguards.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 34 Education 2 2010-07-01 2010-07-01 false Procedural safeguards. 300.121 Section 300.121 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION OF...
-
10 CFR 54.25 - Report of the Advisory Committee on Reactor Safeguards.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 2 2011-01-01 2011-01-01 false Report of the Advisory Committee on Reactor Safeguards. 54.25 Section 54.25 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REQUIREMENTS FOR RENEWAL OF... Reactor Safeguards. Each renewal application will be referred to the Advisory Committee on Reactor...
-
10 CFR 54.25 - Report of the Advisory Committee on Reactor Safeguards.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 2 2010-01-01 2010-01-01 false Report of the Advisory Committee on Reactor Safeguards. 54.25 Section 54.25 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) REQUIREMENTS FOR RENEWAL OF... Reactor Safeguards. Each renewal application will be referred to the Advisory Committee on Reactor...
-
40 CFR 2.211 - Safeguarding of business information; penalty for wrongful disclosure.
Code of Federal Regulations, 2010 CFR
2010-07-01
... for his or her private gain or advantage, any business information which came into his or her... any security procedures for handling and safeguarding business information which are contained in any... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Safeguarding of business information...
-
10 CFR 72.46 - Public hearings.
Code of Federal Regulations, 2010 CFR
2010-01-01
... taking the action, the Director or the Director's designee shall promptly publish a notice in the Federal... public interest, a notice of hearing in accordance with § 2.104 of this chapter. (2) The Director, Office of Nuclear Material Safety and Safeguards, or the Director's designee may dispense with a notice of...