Countermeasures That Work : A Highway Safety Countermeasure Guide For State Highway Safety Offices Sixth Edition, 2011

DOT National Transportation Integrated Search

2011-02-01

This edition of Countermeasures that Work was prepared by the University of North Carolina Highway Safety Research Center (HSRC). Researchers who contributed to this edition include Arthur H. Goodwin, Libby J. Thomas, William L. Hall, and Mary Ellen ...

76 FR 32863 - Guidance for Industry and Investigators on Enforcement of Safety Reporting Requirements for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-07

..., Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51...-40), Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike..., Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51...

An assessment of traffic safety culture related to engagement efforts to improve traffic safety : research programs.

DOT National Transportation Integrated Search

2016-12-01

The Center for Health and Safety Culture at Montana State University developed a survey to investigate the traffic safety culture related to engagement in traffic safety citizenship behaviors. The development of the survey was based on an augmented f...

Aviation Safety/Automation Program Conference

NASA Technical Reports Server (NTRS)

Morello, Samuel A. (Compiler)

1990-01-01

The Aviation Safety/Automation Program Conference - 1989 was sponsored by the NASA Langley Research Center on 11 to 12 October 1989. The conference, held at the Sheraton Beach Inn and Conference Center, Virginia Beach, Virginia, was chaired by Samuel A. Morello. The primary objective of the conference was to ensure effective communication and technology transfer by providing a forum for technical interchange of current operational problems and program results to date. The Aviation Safety/Automation Program has as its primary goal to improve the safety of the national airspace system through the development and integration of human-centered automation technologies for aircraft crews and air traffic controllers.

Ensuring the safety of future PCIVs : paper 09-0316.

DOT National Transportation Integrated Search

2009-06-01

NHTSA, in partnership with Federal agencies, industry, and academia, will support research on safety-centered design and performance modeling and validation to enable and foster superior, integrated safety performance of future light-weight Plastics ...

Safety of Highway-Railroad Grade Crossings : Research Needs Workshop. Volume 2. Appendices.

DOT National Transportation Integrated Search

1996-01-01

The John A. Volpe National Transportation Systems Center hosted and conducted the Highway-Railroad Grade Crossing Safety Research Needs Workshop on April 10 - 13, 1995. Seventy-five delegates participated in the workshop and identified ninety-two (92...

78 FR 6819 - Patient Safety Organizations: Voluntary Relinquishment From The Connecticut Hospital Association...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-31

..., Center for Quality Improvement and Patient Safety, AHRQ, 540 Gaither Road, Rockville, MD 20850; Telephone... DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Patient Safety Organizations: Voluntary Relinquishment From The Connecticut Hospital Association Federal Patient Safety...

Safety in the Chemical Laboratory

ERIC Educational Resources Information Center

Steere, Norman V.

1969-01-01

Presents the Safety Guide used in the Research Center at Monsanto Chemical Company (St. Louis). Topics include: general safety practices, safety glasses and shoes, respiratory protection, electrical wiring, solvent handling and waste disposal. Procedures are given for evacuating, "tagging out, and "locking out. Special mention is given to…

Engaging Community Health Centers (CHCs) in research partnerships: the role of prior research experience on perceived needs and challenges.

PubMed

Beeson, Tishra; Jester, Michelle; Proser, Michelle; Shin, Peter

2014-04-01

Despite community health centers' substantial role in local communities and in the broader safety-net healthcare system, very limited research has been conducted on community health center research experience, infrastructure, or needs from a national perspective. A national survey of 386 community health centers was conducted in 2011 and 2012 to assess research engagement among community health centers and their perceived needs, barriers, challenges, and facilitators with respect to their involvement in public health and health services research. This paper analyzes the differences between health centers that currently conduct or participate in research and health centers that have no prior research experience to determine whether prior research experience is indicative of different perceived challenges and research needs in community health center settings. © 2014 Wiley Periodicals, Inc.

Private highway-rail grade crossing safety research and inquiry

DOT National Transportation Integrated Search

2010-02-01

This report provides a summary of the private highway-rail grade crossing safety inquiry conducted by the United States Department of Transportation Federal Railroad Administration and the Volpe Center. The safety inquiry consisted of a series of pub...

ReactorHealth Physics operations at the NIST center for neutron research.

PubMed

Johnston, Thomas P

2015-02-01

Performing health physics and radiation safety functions under a special nuclear material license and a research and test reactor license at a major government research and development laboratory encompasses many elements not encountered by industrial, general, or broad scope licenses. This article reviews elements of the health physics and radiation safety program at the NIST Center for Neutron Research, including the early history and discovery of the neutron, applications of neutron research, reactor overview, safety and security of radiation sources and radioactive material, and general health physics procedures. These comprise precautions and control of tritium, training program, neutron beam sample processing, laboratory audits, inventory and leak tests, meter calibration, repair and evaluation, radioactive waste management, and emergency response. In addition, the radiation monitoring systems will be reviewed including confinement building monitoring, ventilation filter radiation monitors, secondary coolant monitors, gaseous fission product monitors, gas monitors, ventilation tritium monitor, and the plant effluent monitor systems.

NASA Range Safety Annual Report 2007

NASA Technical Reports Server (NTRS)

Dumont, Alan G.

2007-01-01

As always, Range Safety has been involved in a number of exciting and challenging activities and events. Throughout the year, we have strived to meet our goal of protecting the public, the workforce, and property during range operations. During the past year, Range Safety was involved in the development, implementation, and support of range safety policy. Range Safety training curriculum development was completed this year and several courses were presented. Tailoring exercises concerning the Constellation Program were undertaken with representatives from the Constellation Program, the 45th Space Wing, and the Launch Constellation Range Safety Panel. Range Safety actively supported the Range Commanders Council and it subgroups and remained involved in updating policy related to flight safety systems and flight safety analysis. In addition, Range Safety supported the Space Shuttle Range Safety Panel and addressed policy concerning unmanned aircraft systems. Launch operations at Kennedy Space Center, the Eastern and Western ranges, Dryden Flight Research Center, and Wallops Flight Facility were addressed. Range Safety was also involved in the evaluation of a number of research and development efforts, including the space-based range (formerly STARS), the autonomous flight safety system, the enhanced flight termination system, and the joint advanced range safety system. Flight safety system challenges were evaluated. Range Safety's role in the Space Florida Customer Assistance Service Program for the Eastern Range was covered along with our support for the Space Florida Educational Balloon Release Program. We hope you have found the web-based format both accessible and easy to use. Anyone having questions or wishing to have an article included in the 2008 Range Safety Annual Report should contact Alan Dumont, the NASA Range Safety Program Manager located at the Kennedy Space Center, or Michael Dook at NASA Headquarters.

78 FR 6819 - Patient Safety Organizations: Voluntary Relinquishment From the BREF PSO

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-31

..., Center for Quality Improvement and Patient Safety, AHRQ, 540 Gaither Road, Rockville, MD 20850; Telephone... DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Patient Safety... (AHRQ), HHS. ACTION: Notice of delisting. SUMMARY: The Patient Safety and Quality Improvement Act of...

Evaluating Patient-Centered Outcomes in Clinical Trials of Procedural Sedation, Part 2 Safety: Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research Recommendations.

PubMed

Ward, Denham S; Williams, Mark R; Berkenbosch, John W; Bhatt, Maala; Carlson, Douglas; Chappell, Phillip; Clark, Randall M; Constant, Isabelle; Conway, Aaron; Cravero, Joseph; Dahan, Albert; Dexter, Franklin; Dionne, Raymond; Dworkin, Robert H; Gan, Tong J; Gozal, David; Green, Steven; Irwin, Michael G; Karan, Suzanne; Kochman, Michael; Lerman, Jerrold; Lightdale, Jenifer R; Litman, Ronald S; Mason, Keira P; Miner, James; O'Connor, Robert E; Pandharipande, Pratik; Riker, Richard R; Roback, Mark G; Sessler, Daniel I; Sexton, Anne; Tobin, Joseph R; Turk, Dennis C; Twersky, Rebecca S; Urman, Richard D; Weiss, Mark; Wunsch, Hannah; Zhao-Wong, Anna

2018-05-17

The Sedation Consortium on Endpoints and Procedures for Treatment, Education, and Research, established by the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks, a public-private partnership with the US Food and Drug Administration, convened a second meeting of sedation experts from a variety of clinical specialties and research backgrounds to develop recommendations for procedural sedation research. The previous meeting addressed efficacy and patient- and/or family-centered outcomes. This meeting addressed issues of safety, which was defined as "the avoidance of physical or psychological harm." A literature review identified 133 articles addressing safety measures in procedural sedation clinical trials. After basic reporting of vital signs, the most commonly measured safety parameter was oxygen saturation. Adverse events were inconsistently defined throughout the studies. Only 6 of the 133 studies used a previously validated measure of safety. The meeting identified methodological problems associated with measuring infrequent adverse events. With a consensus discussion, a set of core and supplemental measures were recommended to code for safety in future procedural clinical trials. When adopted, these measures should improve the integration of safety data across studies and facilitate comparisons in systematic reviews and meta-analyses.

NASA-Langley Research Center's Aircraft Condition Analysis and Management System Implementation

NASA Technical Reports Server (NTRS)

Frye, Mark W.; Bailey, Roger M.; Jessup, Artie D.

2004-01-01

This document describes the hardware implementation design and architecture of Aeronautical Radio Incorporated (ARINC)'s Aircraft Condition Analysis and Management System (ACAMS), which was developed at NASA-Langley Research Center (LaRC) for use in its Airborne Research Integrated Experiments System (ARIES) Laboratory. This activity is part of NASA's Aviation Safety Program (AvSP), the Single Aircraft Accident Prevention (SAAP) project to develop safety-enabling technologies for aircraft and airborne systems. The fundamental intent of these technologies is to allow timely intervention or remediation to improve unsafe conditions before they become life threatening.

ETIB tests safety and effectiveness of Baricitinib for chronic GVHD | Center for Cancer Research

Cancer.gov

The Center for Cancer Research has launched a new clinical trial focusing on improving the treatment of chronic graft-versus-host disease, a common adverse reaction that may develop after certain bone marrow transplants.  Learn more...

Evaluation and review of the safety management system implementation in the Royal Thai Air Force

NASA Astrophysics Data System (ADS)

Chaiwan, Sakkarin

This study was designed to determine situation and effectiveness of the safety management system currently implemented in the Royal Thai Air Force. Reviewing the ICAO's SMS and the RTAF's SMS was conducted to identify similarities and differences between the two safety management systems. Later, the researcher acquired safety statistics from the RTAF Safety Center to investigate effectiveness of its safety system. The researcher also collected data to identify other factors affecting effectiveness of the safety system during conducting in-depth interviews. Findings and Conclusions: The study shows that the Royal Thai Air Force has never applied the International Civil Aviation Organization's Safety management System to its safety system. However, the RTAF's SMS and the ICAO's SMS have been developed based on the same concepts. These concepts are from Richard H. Woods's book, Aviation safety programs: A management handbook. However, the effectiveness of the Royal Thai Air Force's safety system is in good stance. An accident rate has been decreasing regularly but there are no known factors to describe the increasing rate, according to the participants' opinion. The participants have informed that there are many issues to be resolved to improve the RTAF's safety system. Those issues are cooperation among safety center's staffs, attitude toward safety of the RTAF senior commanders, and safety standards.

Private highway-rail grade crossing safety research and inquiry. Volume 2 : appendices

DOT National Transportation Integrated Search

2010-02-01

This report provides a summary of the private highway-rail grade crossing safety inquiry conducted by the United States Department of Transportation Federal Railroad Administration and the Volpe Center. The safety inquiry consisted of a series of pub...

From chemicals to cold plasma: Non-thermal food processing technologies research at the USDA's Eastern Regional Research Center

USDA-ARS?s Scientific Manuscript database

Foodborne pathogens cause millions of illnesses every year. At the US Department of Agriculture’s Eastern Regional Research Center, scientists and engineers have focused on developing new ways to improve food safety and shelf life while retaining quality and nutritional value. A variety of technolog...

Traveler Trustworthy Autonomy

NASA Technical Reports Server (NTRS)

Skoog, Mark A.

2016-01-01

NASAs Armstrong Flight Research Center has been engaged in the development of highly automatic safety systems for aviation since the mid 80s. For the past three years under Seedling and Center Innovation funding this work has moved toward the development of a software architecture applicable to autonomous safety. This work is now broadening and accelerating to address the airworthiness issues surrounding making a case for trustworthy autonomy. This software architecture is called the expandable variable-autonomy architecture (EVAA) and utilizes a run-time assurance approach to safety assurance.

USDOT Federal Railroad Administration's third research needs workshop on highway-rail grade crossing safety and trespass prevention : Volume 2 : appendices

DOT National Transportation Integrated Search

2010-01-01

On July 14-16, 2009 the Volpe Center hosted the United States Department of Transportation (US DOT) Federal Railroad Administrations (FRA) Third Research Needs Workshop on Highway-Rail Grade Crossing Safety and Trespass Prevention (workshop). The ...

USDOT Federal Railroad Administration's third research needs workshop on highway-rail grade crossing safety and trespass prevention : Volume I - summary of results

DOT National Transportation Integrated Search

2010-01-01

On July 14-16, 2009 the John A. Volpe National Transportation Center hosted the United States Department of Transportation (USDOT) Federal Railroad Administration's (FRA) Third Research Needs Workshop on Highway-Rail Grade Crossing Safety and Trespas...

First-in-human clinical trial evaluates safety of combination therapy to treat B-cell lymphomas | Center for Cancer Research

Cancer.gov

A new phase I clinical trial to evaluate the safety and maximum tolerated dosage of a five-drug targeted combination therapy called ViPOR for patients with relapsed and treatment-resistant, or refractory, B-cell lymphomas is open at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland. Read more…

Certification Processes for Safety-Critical and Mission-Critical Aerospace Software

NASA Technical Reports Server (NTRS)

Nelson, Stacy

2003-01-01

This document is a quick reference guide with an overview of the processes required to certify safety-critical and mission-critical flight software at selected NASA centers and the FAA. Researchers and software developers can use this guide to jumpstart their understanding of how to get new or enhanced software onboard an aircraft or spacecraft. The introduction contains aerospace industry definitions of safety and safety-critical software, as well as, the current rationale for certification of safety-critical software. The Standards for Safety-Critical Aerospace Software section lists and describes current standards including NASA standards and RTCA DO-178B. The Mission-Critical versus Safety-Critical software section explains the difference between two important classes of software: safety-critical software involving the potential for loss of life due to software failure and mission-critical software involving the potential for aborting a mission due to software failure. The DO-178B Safety-critical Certification Requirements section describes special processes and methods required to obtain a safety-critical certification for aerospace software flying on vehicles under auspices of the FAA. The final two sections give an overview of the certification process used at Dryden Flight Research Center and the approval process at the Jet Propulsion Lab (JPL).

Automated enforcement and highway safety : [tech summary].

DOT National Transportation Integrated Search

2013-11-01

The Louisiana Transportation Research Center (LTRC) funded the Automated Enforcement and Highway Safety project to evaluate : the advantages and disadvantages of automated enforcement at intersections, identify strategies to enhance public opinion re...

The Nanotoxicology Research Program in NIOSH

NASA Astrophysics Data System (ADS)

Castranova, Vincent

2009-01-01

The National Institute for Occupational Safety and Health through its Nanotechnology Research Center has developed a Strategic Plan for Nanotechnology Safety and Health Research. This Strategic Plan identified knowledge gaps and critical issues, which must be addressed to protect the health and safety of workers producing nanoparticles as well as those incorporating nanoparticles into commercial products or using nanomaterials in novel applications. This manuscript lists the projects that comprise the Nanotoxicology Program in NIOSH and provides a brief description of the goals and accomplishments of these projects.

T-34C in flight

NASA Image and Video Library

1997-03-21

A NASA T-34C aircraft, used for safety chase, is shown flying above the Dryden Flight Research Center, Edwards, California in March 1997. The aircraft was previously used at the Lewis Research Center in propulsion experiments involving turboprop engines, and was used as a chase aircraft at Dryden for smaller and slower research projects. Chase aircraft accompany research flights for photography and video purposes, and also as support for safety and research. At Dryden, the T-34 is used mainly for smaller remotely piloted vehicles which fly slower than NASA's F-18's, used for larger scale projects. This aircraft was returned to the U.S. Navy in May of 2002. The T-34C, built by Beech, carries a crew of 2 and is nicknamed the Mentor.

Motor vehicle attributes : status report

DOT National Transportation Integrated Search

1985-03-01

The Transportation Systems Center (TSC) was requested by the National Highway : Traffic Safety Administration's (NHTSA) Office of Vehicle Research to compile : and computerize a data base of vehicle safety attributes for automobiles and : trucks. The...

Improving driver safety with behavioral countermeasures.

DOT National Transportation Integrated Search

2011-09-30

"The purpose of this project was to provide MDOT with insight regarding the effectiveness of potential implementations of behavioral countermeasures for increasing driver safety in Michigan. The Center for Driver Evaluation, Education, and Research a...

42 CFR 87.1 - To which programs does this regulation apply?

Code of Federal Regulations, 2010 CFR

2010-10-01

... National Institute for Occupational Safety and Health, Centers for Disease Control, of the Public Health... Section 87.1 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH...

77 FR 73662 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-11

... announced below concerns Occupational Safety and Health Education and Research Centers (ERC) PAR 10-217... evaluation of applications received in response to ``Occupational Safety and Health Education and Research... Officer, CDC/NIOSH, 626 Cochrans Mill Road, Mailstop P-05, Pittsburgh, Pennsylvania 15236, Telephone: (412...

Deployment of sustainable fueling/charging systems at California highway safety roadside rest areas : a research report from the National Center for Sustainable Transportation.

DOT National Transportation Integrated Search

2016-12-01

The objectives of this research were to study the feasibility of the deployment of renewable hydrogen fueling/DC fast charging stations at California Safety Roadside Rest Areas (SRRAs), not at service areas with commercial activity, and the integrati...

Biosurveillance at the United States Meat Animal Research Center

USDA-ARS?s Scientific Manuscript database

The mission of the 50 scientists and 165 support staff at the U.S. Meat Animal Research Center (USMARC) is to develop new technologies to increase the efficiency of livestock production and improve meat safety, quality, and animal health to benefit consumers worldwide. The facilities include 35,000 ...

Developing the Safety of Atrial Fibrillation Ablation Registry Initiative (SAFARI) as a collaborative pan-stakeholder critical path registry model: a Cardiac Safety Research Consortium "Incubator" Think Tank.

PubMed

Al-Khatib, Sana M; Calkins, Hugh; Eloff, Benjamin C; Kowey, Peter; Hammill, Stephen C; Ellenbogen, Kenneth A; Marinac-Dabic, Danica; Waldo, Albert L; Brindis, Ralph G; Wilbur, David J; Jackman, Warren M; Yaross, Marcia S; Russo, Andrea M; Prystowsky, Eric; Varosy, Paul D; Gross, Thomas; Pinnow, Ellen; Turakhia, Mintu P; Krucoff, Mitchell W

2010-10-01

Although several randomized clinical trials have demonstrated the safety and efficacy of catheter ablation of atrial fibrillation (AF) in experienced centers, the outcomes of this procedure in routine clinical practice and in patients with persistent and long-standing persistent AF remain uncertain. Brisk adoption of this therapy by physicians with diverse training and experience highlights potential concerns regarding the safety and effectiveness of this procedure. Some of these concerns could be addressed by a national registry of AF ablation procedures such as the Safety of Atrial Fibrillation Ablation Registry Initiative that was initially proposed at a Cardiac Safety Research Consortium Think Tank meeting in April 2009. In January 2010, the Cardiac Safety Research Consortium, in collaboration with the Duke Clinical Research Institute, the US Food and Drug Administration, the American College of Cardiology, and the Heart Rhythm Society, held a follow-up meeting of experts in the field to review the construct and progress to date. Other participants included the National Heart, Lung, and Blood Institute; the Centers for Medicare and Medicaid Services; the Agency for Healthcare Research and Quality; the AdvaMed AF working group; and additional industry representatives. This article summarizes the discussions that occurred at the meeting of the state of the Safety of Atrial Fibrillation Ablation Registry Initiative, the identification of a clear pathway for its implementation, and the exploration of solutions to potential issues in the execution of this registry. Copyright © 2010 Mosby, Inc. All rights reserved.

Researchers studying alternative to bladder removal for bladder cancer patients | Center for Cancer Research

Cancer.gov

A new phase I clinical trial conducted by researchers at the Center for Cancer Research (CCR) is evaluating the safety and tolerability, or the degree to which any side effects can be tolerated by patients, of a two-drug combination as a potential alternative to bladder removal for bladder cancer patients. The trial targets patients with non-muscle invasive bladder cancer

Risk analysis based CWR track buckling safety evaluations

DOT National Transportation Integrated Search

2001-01-01

As part of the Federal Railroad Administrations (FRA) track systems research program, the US DOTS Volpe Center is conducting analytic and experimental investigations to evaluate track lateral strength and stability limits for improved safety an...

Calibration Laboratory Capabilities Listing as of April 2009

NASA Technical Reports Server (NTRS)

Kennedy, Gary W.

2009-01-01

This document reviews the Calibration Laboratory capabilities for various NASA centers (i.e., Glenn Research Center and Plum Brook Test Facility Kennedy Space Center Marshall Space Flight Center Stennis Space Center and White Sands Test Facility.) Some of the parameters reported are: Alternating current, direct current, dimensional, mass, force, torque, pressure and vacuum, safety, and thermodynamics parameters. Some centers reported other parameters.

Building Safer Systems With SpecTRM

NASA Technical Reports Server (NTRS)

2003-01-01

System safety, an integral component in software development, often poses a challenge to engineers designing computer-based systems. While the relaxed constraints on software design allow for increased power and flexibility, this flexibility introduces more possibilities for error. As a result, system engineers must identify the design constraints necessary to maintain safety and ensure that the system and software design enforces them. Safeware Engineering Corporation, of Seattle, Washington, provides the information, tools, and techniques to accomplish this task with its Specification Tools and Requirements Methodology (SpecTRM). NASA assisted in developing this engineering toolset by awarding the company several Small Business Innovation Research (SBIR) contracts with Ames Research Center and Langley Research Center. The technology benefits NASA through its applications for Space Station rendezvous and docking. SpecTRM aids system and software engineers in developing specifications for large, complex safety critical systems. The product enables engineers to find errors early in development so that they can be fixed with the lowest cost and impact on the system design. SpecTRM traces both the requirements and design rationale (including safety constraints) throughout the system design and documentation, allowing engineers to build required system properties into the design from the beginning, rather than emphasizing assessment at the end of the development process when changes are limited and costly.System safety, an integral component in software development, often poses a challenge to engineers designing computer-based systems. While the relaxed constraints on software design allow for increased power and flexibility, this flexibility introduces more possibilities for error. As a result, system engineers must identify the design constraints necessary to maintain safety and ensure that the system and software design enforces them. Safeware Engineering Corporation, of Seattle, Washington, provides the information, tools, and techniques to accomplish this task with its Specification Tools and Requirements Methodology (SpecTRM). NASA assisted in developing this engineering toolset by awarding the company several Small Business Innovation Research (SBIR) contracts with Ames Research Center and Langley Research Center. The technology benefits NASA through its applications for Space Station rendezvous and docking. SpecTRM aids system and software engineers in developing specifications for large, complex safety critical systems. The product enables engineers to find errors early in development so that they can be fixed with the lowest cost and impact on the system design. SpecTRM traces both the requirements and design rationale (including safety constraints) throughout the system design and documentation, allowing engineers to build required system properties into the design from the beginning, rather than emphasizing assessment at the end of the development process when changes are limited and costly.

Risk analysis based CWR track buckling safety evaluations

DOT National Transportation Integrated Search

1999-12-01

As part of the Federal Railroad Administration's (FRA) track systems research program, the US DOT'S Volpe Center is conducting analytic and experimental investigations to evaluate track lateral strength and stability limits for improved safety and pe...

Motor Carrier Safety Fitness Determination: An Improved Process

DOT National Transportation Integrated Search

1996-12-01

PREFACE This report was undertaken to define an improved process for motor carrier safety fitness determination. It was produced by the Research and Special Program Administration's (RSPA} John A. Volpe National Transportation Systems Center (the Vol...

A Process-Centered Tool for Evaluating Patient Safety Performance and Guiding Strategic Improvement

DTIC Science & Technology

2005-01-01

next patient safety steps in individual health care organizations. The low priority given to Category 3 (Focus on patients , other customers , and...presents a patient safety applicator tool for implementing and assessing patient safety systems in health care institutions. The applicator tool consists...the survey rounds. The study addressed three research questions: 1. What critical processes should be included in health care patient safety systems

75 FR 59935 - Investigational New Drug Safety Reporting Requirements for Human Drug and Biological Products and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... safety reporting for human drug products: Janet Norden, Center for Drug Evaluation and Research, Food and... for Biologics Evaluation and Research, Food and Drug Administration,1401 Rockville Pike, suite 200N..., 2003. At the request of industry, and to provide all interested persons additional time to comment, the...

Child contact centers and domestic abuse: victim safety and the challenge to neutrality.

PubMed

Morrison, Fiona; Wasoff, Fran

2012-06-01

Child contact with a nonresident father who has perpetrated domestic abuse has gained policy and research attention. Both feminist social policy and family law research identify the role child contact centers can play in facilitating contact in these circumstances. Drawing from a literature review carried out by the authors, this article examines the priorities that underpin feminist social policy and family law disciplines and how these manifest in research on contact centers and domestic abuse.

New clinical trial explores precision treatment for advanced pancreatic cancer | Center for Cancer Research

Cancer.gov

A new phase II clinical trial to assess the safety and efficacy of a drug called selumetinib for treating patients with advanced pancreatic cancer whose tumors harbor a specific genetic marker has opened at the Center for Cancer Research and is currently recruiting participants. Read more...

21 CFR 860.7 - Determination of safety and effectiveness.

Code of Federal Regulations, 2011 CFR

2011-04-01

... diagnosis with a control in such a fashion as to permit quantitative evaluation. The precise nature of the... Devices and Radiological Health, the Center for Biologics Evaluation and Research, or the Center for Drug Evaluation and Research, as applicable, need not be resubmitted, but may be incorporated by reference. [43 FR...

21 CFR 860.7 - Determination of safety and effectiveness.

Code of Federal Regulations, 2013 CFR

2013-04-01

... diagnosis with a control in such a fashion as to permit quantitative evaluation. The precise nature of the... Devices and Radiological Health, the Center for Biologics Evaluation and Research, or the Center for Drug Evaluation and Research, as applicable, need not be resubmitted, but may be incorporated by reference. [43 FR...

21 CFR 860.7 - Determination of safety and effectiveness.

Code of Federal Regulations, 2014 CFR

2014-04-01

... diagnosis with a control in such a fashion as to permit quantitative evaluation. The precise nature of the... Devices and Radiological Health, the Center for Biologics Evaluation and Research, or the Center for Drug Evaluation and Research, as applicable, need not be resubmitted, but may be incorporated by reference. [43 FR...

21 CFR 860.7 - Determination of safety and effectiveness.

Code of Federal Regulations, 2010 CFR

2010-04-01

... diagnosis with a control in such a fashion as to permit quantitative evaluation. The precise nature of the... Devices and Radiological Health, the Center for Biologics Evaluation and Research, or the Center for Drug Evaluation and Research, as applicable, need not be resubmitted, but may be incorporated by reference. [43 FR...

21 CFR 860.7 - Determination of safety and effectiveness.

Code of Federal Regulations, 2012 CFR

2012-04-01

... diagnosis with a control in such a fashion as to permit quantitative evaluation. The precise nature of the... Devices and Radiological Health, the Center for Biologics Evaluation and Research, or the Center for Drug Evaluation and Research, as applicable, need not be resubmitted, but may be incorporated by reference. [43 FR...

Corporate Average Fuel Economy Compliance and Effects Modeling System Documentation

DOT National Transportation Integrated Search

2009-04-01

The Volpe National Transportation Systems Center (Volpe Center) of the United States Department of Transportation's Research and Innovative Technology Administration has developed a modeling system to assist the National Highway Traffic Safety Admini...

Macroergonomics in Healthcare Quality and Patient Safety

PubMed Central

Carayon, Pascale; Karsh, Ben-Tzion; Gurses, Ayse P.; Holden, Richard; Hoonakker, Peter; Hundt, Ann Schoofs; Montague, Enid; Rodriguez, Joy; Wetterneck, Tosha B.

2014-01-01

The US Institute of Medicine and healthcare experts have called for new approaches to manage healthcare quality problems. In this chapter, we focus on macroergonomics, a branch of human factors and ergonomics that is based on the systems approach and considers the organizational and sociotechnical context of work activities and processes. Selected macroergonomic approaches to healthcare quality and patient safety are described such as the SEIPS model of work system and patient safety and the model of healthcare professional performance. Focused reviews on job stress and burnout, workload, interruptions, patient-centered care, health IT and medical devices, violations, and care coordination provide examples of macroergonomics contributions to healthcare quality and patient safety. Healthcare systems and processes clearly need to be systematically redesigned; examples of macroergonomic approaches, principles and methods for healthcare system redesign are described. Further research linking macroergonomics and care processes/patient outcomes is needed. Other needs for macroergonomics research are highlighted, including understanding the link between worker outcomes (e.g., safety and well-being) and patient outcomes (e.g., patient safety), and macroergonomics of patient-centered care and care coordination. PMID:24729777

Women's Health and Complementary Approaches

MedlinePlus

... Information Center Ongoing Medical Studies Find Active Medical Research Studies on Cranberry (ClinicalTrials.gov) Find Active Medical Research Studies on Menopause (ClinicalTrials.gov) Safety Information Dream Body ...

Combination products regulation at the FDA.

PubMed

Lauritsen, K J; Nguyen, T

2009-05-01

The US Food and Drug Administration (FDA) is responsible for protecting the public health by assuring the safety, efficacy, and security of drugs, biological products, and medical devices. As single-entity products, drugs are generally regulated by the Center for Drug Evaluation and Research (CDER), devices by the Center for Devices and Radiological Health (CDRH), and biologics by the Center for Biologics Evaluation and Research (CBER). In recent years, technological advances have led to a blurring of the historical lines of separation between the centers.

Report of the workshop on Aviation Safety/Automation Program

NASA Technical Reports Server (NTRS)

Morello, Samuel A. (Editor)

1990-01-01

As part of NASA's responsibility to encourage and facilitate active exchange of information and ideas among members of the aviation community, an Aviation Safety/Automation workshop was organized and sponsored by the Flight Management Division of NASA Langley Research Center. The one-day workshop was held on October 10, 1989, at the Sheraton Beach Inn and Conference Center in Virginia Beach, Virginia. Participants were invited from industry, government, and universities to discuss critical questions and issues concerning the rapid introduction and utilization of advanced computer-based technology into the flight deck and air traffic controller workstation environments. The workshop was attended by approximately 30 discipline experts, automation and human factors researchers, and research and development managers. The goal of the workshop was to address major issues identified by the NASA Aviation Safety/Automation Program. Here, the results of the workshop are documented. The ideas, thoughts, and concepts were developed by the workshop participants. The findings, however, have been synthesized into a final report primarily by the NASA researchers.

Parametric study of track response

DOT National Transportation Integrated Search

1977-12-01

This report was prepared as part of the Improved Track Structures Research Program : managed by the Transportation Systems Center. This program is sponsored by the : Office of Rail Safety Research, Improved Track Structures Research Division, of : th...

2012 - 2016 Corporate Average Fuel Economy compliance and effects modeling system documentation

DOT National Transportation Integrated Search

2010-03-01

The Volpe National Transportation Systems Center (Volpe Center) of the United States Department of Transportation's Research and Innovative Technology Administration has developed a modeling system to assist the National Highway Traffic Safety Admini...

2017 - 2025 Corporate Average Fuel Economy Compliance and Effects Modeling System Documentation.

DOT National Transportation Integrated Search

2012-08-31

The Volpe National Transportation Systems Center (Volpe Center) of the United States Department of Transportations Research and Innovative Technology Administration has developed a modeling system to assist the National Highway Traffic Safety Admi...

Student Work Safety Guidelines in Roadside Applications and Work Zones : Safety Guidelines for Transportation Researchers

DOT National Transportation Integrated Search

2018-01-01

The Smart City Demonstration Program is intended to improve access through expanded mobility options in major job centers, enhance visitor experience by better connecting visitors to transportation options, stimulate regional economic prosperity and ...

Aviation safety and automation technology for subsonic transports

NASA Technical Reports Server (NTRS)

Albers, James A.

1991-01-01

Discussed here are aviation safety human factors and air traffic control (ATC) automation research conducted at the NASA Ames Research Center. Research results are given in the areas of flight deck and ATC automations, displays and warning systems, crew coordination, and crew fatigue and jet lag. Accident investigation and an incident reporting system that is used to guide the human factors research is discussed. A design philosophy for human-centered automation is given, along with an evaluation of automation on advanced technology transports. Intelligent error tolerant systems such as electronic checklists are discussed along with design guidelines for reducing procedure errors. The data on evaluation of Crew Resource Management (CRM) training indicates highly significant positive changes in appropriate flight deck behavior and more effective use of available resources for crew members receiving the training.

Research and technology at the Kennedy Space Center

NASA Technical Reports Server (NTRS)

1983-01-01

Cryogenic engineering, hypergolic engineering, hazardous warning, structures and mechanics, computer sciences, communications, meteorology, technology applications, safety engineering, materials analysis, biomedicine, and engineering management and training aids research are reviewed.

Use of the Home Safety Self-Assessment Tool (HSSAT) within Community Health Education to Improve Home Safety.

PubMed

Horowitz, Beverly P; Almonte, Tiffany; Vasil, Andrea

2016-10-01

This exploratory research examined the benefits of a health education program utilizing the Home Safety Self-Assessment Tool (HSSAT) to increase perceived knowledge of home safety, recognition of unsafe activities, ability to safely perform activities, and develop home safety plans of 47 older adults. Focus groups in two senior centers explored social workers' perspectives on use of the HSSAT in community practice. Results for the health education program found significant differences between reported knowledge of home safety (p = .02), ability to recognize unsafe activities (p = .01), safely perform activities (p = .04), and develop a safety plan (p = .002). Social workers identified home safety as a major concern and the HSSAT a promising assessment tool. Research has implications for reducing environmental fall risks.

Sandia National Laboratories: Cooperative Monitoring Center

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Icing Research Tunnel (IRT) Force Measurement System (FMS)

NASA Technical Reports Server (NTRS)

Roberts, Paul W.

2012-01-01

An Electronics Engineer at the Glenn Research Center (GRC), requested the NASA Engineering and Safety Center (NESC) provide technical support for an evaluation of the existing force measurement system (FMS) at the GRC's Icing Research Tunnel (IRT) with the intent of developing conceptual designs to improve the tunnel's force measurement capability in order to better meet test customer needs. This report contains the outcome of the NESC technical review.

Large trucks involved in fatal crashes : the North Carolina data 1993-1997

DOT National Transportation Integrated Search

1999-03-01

An analysis of large, truck-involved crash outcomes in North Carolina for the period 1993-1997 was conducted by the UNC Highway Safety Research Center (HSRC) for the purpose of establishing an empirical basis for subsequent Governor's Highway Safety ...

Researchers studying alternative to bladder removal for bladder cancer patients | Center for Cancer Research

Cancer.gov

A new phase I clinical trial conducted by researchers at the Center for Cancer Research (CCR) is evaluating the safety and tolerability, or the degree to which any side effects can be tolerated by patients, of a two-drug combination as a potential alternative to bladder removal for bladder cancer patients. The trial targets patients with non-muscle invasive bladder cancer (NMIBC) whose cancers have stopped responding to traditional therapies. Read more...

Sandia National Laboratories: Microsystems Science & Technology Center

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Proceedings of Twenty-Seventh Annual Institute on Mining Health, Safety and Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bockosh, G.R.; Langton, J.; Karmis, M.

1996-12-31

This Proceedings contains the presentations made during the program of the Twenty-Seventh Annual Institute on Mining Health, Safety and Research held at Virginia Polytechnic Institute and State University, Blacksburg, Virginia, on August 26-28, 1996. The Twenty-Seventh Annual Institute on Mining, Health, Safety and Research was the latest in a series of conferences held at Virginia Polytechnic Institute and State University, cosponsored by the Mine Safety and Health Administration, United States Department of Labor, and the Pittsburgh Research Center, United States Department of Energy (formerly part of the Bureau of Mines, U. S. Department of Interior). The Institute provides an informationmore » forum for mine operators, managers, superintendents, safety directors, engineers, inspectors, researchers, teachers, state agency officials, and others with a responsible interest in the important field of mining health, safety and research. In particular, the Institute is designed to help mine operating personnel gain a broader knowledge and understanding of the various aspects of mining health and safety, and to present them with methods of control and solutions developed through research. Selected papers have been processed separately for inclusion in the Energy Science and Technology database.« less

NASA aviation safety program aircraft engine health management data mining tools roadmap

DOT National Transportation Integrated Search

2000-04-01

Aircraft Engine Health Management Data Mining Tools is a project led by NASA Glenn Research Center in support of the NASA Aviation Safety Program's Aviation System Monitoring and Modeling Thrust. The objective of the Glenn-led effort is to develop en...

Industrial Hygiene Issues

NASA Technical Reports Server (NTRS)

Brisbin, Steven G.

1999-01-01

This breakout session is a traditional conference instrument used by the NASA industrial hygiene personnel as a method to convene personnel across the Agency with common interests. This particular session focused on two key topics, training systems and automation of industrial hygiene data. During the FY 98 NASA Occupational Health Benchmarking study, the training system under development by the U.S. Environmental Protection Agency (EPA) was deemed to represent a "best business practice." The EPA has invested extensively in the development of computer based training covering a broad range of safety, health and environmental topics. Currently, five compact disks have been developed covering the topics listed: Safety, Health and Environmental Management Training for Field Inspection Activities; EPA Basic Radiation Training Safety Course; The OSHA 600 Collateral Duty Safety and Health Course; and Key program topics in environmental compliance, health and safety. Mr. Chris Johnson presented an overview of the EPA compact disk-based training system and answered questions on its deployment and use across the EPA. This training system has also recently been broadly distributed across other Federal Agencies. The EPA training system is considered "public domain" and, as such, is available to NASA at no cost in its current form. Copies of the five CD set of training programs were distributed to each NASA Center represented in the breakout session. Mr. Brisbin requested that each NASA Center review the training materials and determine whether there is interest in using the materials as it is or requesting that EPA tailor the training modules to suit NASA's training program needs. The Safety, Health and Medical Services organization at Ames Research Center has completed automation of several key program areas. Mr. Patrick Hogan, Safety Program Manager for Ames Research Center, presented a demonstration of the automated systems, which are described by the following: (1) Safety, Health and Environmental Training. This system includes an assessment of training needs for every NASA Center organization, course descriptions, schedules and automated course scheduling, and presentation of training program metrics; (2) Safety and Health Inspection Information. This system documents the findings from each facility inspection, tracks abatement status on those findings and presents metrics on each department for senior management review; (3) Safety Performance Evaluation Profile. The survey system used by NASA to evaluate employee and supervisory perceptions of safety programs is automated in this system; and (4) Documentation Tracking System. Electronic archive and retrieval of all correspondence and technical reports generated by the Safety, Health and Medical Services Office are provided by this system.

Comparative assessment of crash causal factors and IVHS countermeasures

DOT National Transportation Integrated Search

1994-01-01

The National Highway Traffic Safety Administrations Office of Crash Avoidance Research, in : conjunction with the Research and Special Programs Administrations Volpe National : Transportation Systems Center, has underway a multi-disciplinary pr...

Safety climate and attitude as evaluation measures of organizational safety.

PubMed

Isla Díaz, R; Díaz Cabrera, D

1997-09-01

The main aim of this research is to develop a set of evaluation measures for safety attitudes and safety climate. Specifically it is intended: (a) to test the instruments; (b) to identify the essential dimensions of the safety climate in the airport ground handling companies; (c) to assess the quality of the differences in the safety climate for each company and its relation to the accident rate; (d) to analyse the relationship between attitudes and safety climate; and (e) to evaluate the influences of situational and personal factors on both safety climate and attitude. The study sample consisted of 166 subjects from three airport companies. Specifically, this research was centered on ground handling departments. The factor analysis of the safety climate instrument resulted in six factors which explained 69.8% of the total variance. We found significant differences in safety attitudes and climate in relation to type of enterprise.

Beyond the classroom: a case study of immigrant safety liaisons in residential construction.

PubMed

Ochsner, Michele; Marshall, Elizabeth G; Martino, Carmen; Pabelón, Marién Casillas; Kimmel, Louis; Rostran, Damaris

2012-01-01

Latino day laborers often work at dangerous construction sites with little power to change conditions. We describe the development, implementation, and early-stage results of a program to train immigrant day laborers as safety liaisons. These are construction workers prepared to recognize and respond to health and safety hazards. Based in Newark, NJ, the project involves collaboration between New Labor, a membership-based worker center, and university researchers and labor educators. Safety liaisons undergo training and receive ongoing support for their roles. Both qualitative and quantitative data are collected to monitor progress. Although lacking in formal authority, safety liaisons have prompted improvements at specific sites, filed OSHA complaints, and developed a local worker council. Participatory training methods, opportunities for leadership outside the classroom, and participation in project planning have strengthened liaisons' effectiveness, leadership skills, and commitment. The safety liaison approach could be adapted by worker centers and their partner organizations.

Assessment of Tribal Bison Worker Hazards Using Trusted Research Facilitators.

PubMed

Duysen, Ellen; Irvine, Kelsey; Yoder, Aaron; Topliff, Christina; Kelling, Clayton; Rajaram, Shireen

2017-01-01

Agriculture is one of the most hazardous industries in the United States. Within agriculture, livestock handling is particularly dangerous. While injury and fatality rates for bison handlers have not been reported, workers in many of the newly established tribal bison herds have limited safety training and animal handling experience, making this a vulnerable workforce. Veterinarians and herd managers, working with tribal bison herds, recognized the need for improvement in the working environment and for worker safety training. In response, partnerships were established and a pilot project was developed in order to characterize risks and hazards associated with bison handling under contemporary reservation field conditions. Individuals and organizations working as change agents included veterinarians at the University of Nebraska - Lincoln School of Veterinary Medicine, a tribal advocacy organization, the Intertribal Buffalo Council and researchers at the Central States Center for Agricultural Safety and Health at the University of Nebraska Medical Center. This is a mixed-methods study and data were gathered through closed and open-ended questions pertaining to bison worker safety hazards. A veterinarian gathered data through observational safety audits at bison herding locations. American Indian bison herd managers completed surveys using a convenience sampling method. Findings indicate that the most common worker safety risks are associated with the use of high-stress handling methods and substandard facilities and equipment. Adverse environmental conditions also contribute to worker health risks. Most common causes of injuries included those caused by equipment and tools, adverse weather, and direct contact with animals. This collaborative research study contributes to a better understanding of hazards faced by tribal bison workers. Findings from this research influenced the ITBC in their decision to add worker safety and health training to the agenda of their yearly conference and promote tailgate trainings for their workers. UNL veterinarians have taken the lessons learned from this research and provided safety and health information to mangers of other non-tribal bison herds. This research partnership will continue with a 5-year research study focusing on best management practices and establishing training to improve the health and safety bison workers.

Safety management of a complex R and D ground operating system

NASA Technical Reports Server (NTRS)

Connors, J. F.; Maurer, R. A.

1975-01-01

A perspective on safety program management was developed for a complex R&D operating system, such as the NASA-Lewis Research Center. Using a systems approach, hazardous operations are subjected to third-party reviews by designated-area safety committees and are maintained under safety permit controls. To insure personnel alertness, emergency containment forces and employees are trained in dry-run emergency simulation exercises. The keys to real safety effectiveness are top management support and visibility of residual risks.

Safety management of a complex R&D ground operating system

NASA Technical Reports Server (NTRS)

Connors, J. F.; Maurer, R. A.

1975-01-01

A perspective on safety program management has been developed for a complex R&D operating system, such as the NASA-Lewis Research Center. Using a systems approach, hazardous operations are subjected to third-party reviews by designated area safety committees and are maintained under safety permit controls. To insure personnel alertness, emergency containment forces and employees are trained in dry-run emergency simulation exercises. The keys to real safety effectiveness are top management support and visibility of residual risks.

Cognitive engineering in aerospace applications

NASA Technical Reports Server (NTRS)

Woods, David D.

1993-01-01

The progress that was made with respect to the objectives and goals of the research that is being carried out in the Cognitive Systems Engineering Laboratory (CSEL) under a Cooperative Agreement with NASA Ames Research Center is described. The major objective of this project is to expand the research base in Cognitive Engineering to be able to support the development and human-centered design of automated systems for aerospace applications. This research project is in support of the Aviation Safety/Automation Research plan and related NASA research goals in space applications.

Engineers and technicians in the control room at the Dryden Flight Research Center must constantly monitor critical operations and checks during research projects like NASA's hypersonic X-43A

NASA Image and Video Library

2004-01-24

Engineers and technicians in the control room at the Dryden Flight Research Center must constantly monitor critical operations and checks during research projects like NASA's hypersonic X-43A. Visible in the photo, taken two days before the X-43's captive carry flight in January 2004, are [foreground to background]; Tony Kawano (Range Safety Officer), Brad Neal (Mission Controller), and Griffin Corpening (Test Conductor).

Enforcement, adjudication and public information strategies for the general deterrence of driving while intoxicated : information for potential field site participants

DOT National Transportation Integrated Search

1982-10-01

The National Highway Traffic Safety Administration (NHTSA) through a contract with the University of North Carolina Highway Safety Research Center (HSRC) is intending to field test the effectiveness of selected general deterrence programs directed at...

Safety, Reliability, and Quality Assurance Provisions for the Office of Aeronautics, Exploration and Technology Centers

NASA Technical Reports Server (NTRS)

1991-01-01

This Handbook establishes general safety, reliability, and quality assurance (SR&QA) guidelines for use on flight and ground-based projects conducted at the Ames, Langley, and Lewis Research Centers, hereafter identified as the Office of Aeronautics, Exploration and Technology (OAET) Centers. This document is applicable to all projects and operations conducted at these Centers except for those projects covered by more restrictive provisions such as the Space Shuttle, Space Station, and unmanned spacecraft programs. This Handbook is divided into two parts. The first (Chapters 1 and 2) establishes the SR&QA guidelines applicable to the OAET Centers, and the second (Appendices A, B, C, and D) provides examples and definitions for the total SR&QA program. Each center should implement SR&QA programs using these guidelines with tailoring appropriate to the special projects conducted by each Center. This Handbook is issued in loose-leaf form and will be revised by page changes.

Mitigating Motion Base Safety Issues: The NASA LaRC CMF Implementation

NASA Technical Reports Server (NTRS)

Bryant, Richard B., Jr.; Grupton, Lawrence E.; Martinez, Debbie; Carrelli, David J.

2005-01-01

The NASA Langley Research Center (LaRC), Cockpit Motion Facility (CMF) motion base design has taken advantage of inherent hydraulic characteristics to implement safety features using hardware solutions only. Motion system safety has always been a concern and its implementation is addressed differently by each organization. Some approaches rely heavily on software safety features. Software which performs safety functions is subject to more scrutiny making its approval, modification, and development time consuming and expensive. The NASA LaRC's CMF motion system is used for research and, as such, requires that the software be updated or modified frequently. The CMF's customers need the ability to update the simulation software frequently without the associated cost incurred with safety critical software. This paper describes the CMF engineering team's approach to achieving motion base safety by designing and implementing all safety features in hardware, resulting in applications software (including motion cueing and actuator dynamic control) being completely independent of the safety devices. This allows the CMF safety systems to remain intact and unaffected by frequent research system modifications.

Electronic availability of microgravity experiments safety and integration requirements documents

NASA Technical Reports Server (NTRS)

Hogan, Jean M.

1995-01-01

This follow-on to NASA Contractor Report 195447, Microgravity Experiments Safety and Integration Requirements Document Tree, provides the details for accessing the systems that contain the official, electronic versions of the documents initially researched in NASA Contractor Report 195447. The data in this report serves as a valuable information source for the NASA Lewis Research Center Project Documentation Center (PDC), as well as for all developers of space experiments. The PDC has acquired the hardware, software, ID's, and passwords necessary to access most of these systems and is now able to provide customers with current document information as well as immediate delivery of available documents in either electronic or hard copy format.

School-Based Health Care and the District of Columbia Safety Net. Medical Homes DC Report

ERIC Educational Resources Information Center

21st Century School Fund, 2004

2004-01-01

This report provides the results of research into the variety of health care services currently offered in the public schools in the District of Columbia, with a particular focus on school-based health centers. Also provided are the results of research into the practice of utilizing school-based health centers nationally in the U.S. The report is…

Introduction to HACCP.

USDA-ARS?s Scientific Manuscript database

Introduction to HACCP Deana R. Jones, Ph.D. Egg Safety and Quality Research Unit USDA-Agricultural Research Service Russell Research Center Athens, GA Deana.Jones@ars.usda.gov HACCP is an acronym for Hazard Analysis and Critical Control Point and was initially developed by the Pillsbury Company a...

21 CFR 814.100 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-04-01

... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... public health and safety and with ethical standards, to encourage the discovery and use of devices...), Center for Devices and Radiological Health (CDRH), the Center for Biologics Evaluation and Research (CBER...

Development and Validation of a Short-Form Safety Net Medical Home Scale.

PubMed

Nocon, Robert S; Gunter, Kathryn E; Gao, Yue; Lee, Sang Mee; Chin, Marshall H

2017-12-01

To develop a short-form Safety Net Medical Home Scale (SNMHS) for assessing patient-centered medical home (PCMH) capability in safety net clinics. National surveys of federally qualified health centers (FQHCs). Interviews with FQHC directors. We constructed three short-form SNMHS versions and examined correlations with full SNMHS and related primary care assessments. We tested usability with FQHC directors and reviewed scale development with an advisory group. Federally qualified health center surveys were administered in 2009 and 2013, by mail and online. Usability testing was conducted through telephone interviews with FQHC directors in 2013. Six-, 12-, and 18-question short-form SNMHS versions had Pearson correlations with full scale of 0.84, 0.92, and 0.96, respectively. All versions showed a level of convergent validity with other primary care assessment scales comparable to the full SNMHS. User testers found short forms to be low-burden, though missing some PCMH concepts. Advisory group members expressed caution over missing concepts and appropriate use of short-form self-assessments. Short-form versions of SNMHS showed strong correlations with full scale and may be useful for brief assessment of safety net PCMH capability. Each short-form SNMHS version may be appropriate for different research, quality improvement, and assessment purposes. © Health Research and Educational Trust.

Airline Safety and Economy

NASA Technical Reports Server (NTRS)

1993-01-01

This video documents efforts at NASA Langley Research Center to improve safety and economy in aircraft. Featured are the cockpit weather information needs computer system, which relays real time weather information to the pilot, and efforts to improve techniques to detect structural flaws and corrosion, such as the thermal bond inspection system.

Field studies of safety security rescue technologies through training and response activities

NASA Astrophysics Data System (ADS)

Murphy, Robin R.; Stover, Sam

2006-05-01

This paper describes the field-oriented philosophy of the Institute for Safety Security Rescue Technology (iSSRT) and summarizes the activities and lessons learned during calendar year 2005 of its two centers: the Center for Robot-Assisted Search and Rescue and the NSF Safety Security Rescue industry/university cooperative research center. In 2005, iSSRT participated in four responses (La Conchita, CA, Mudslides, Hurricane Dennis, Hurricane Katrina, Hurricane Wilma) and conducted three field experiments (NJTF-1, Camp Hurricane, Richmond, MO). The lessons learned covered mobility, operator control units, wireless communications, and general reliability. The work has collectively identified six emerging issues for future work. Based on these studies, a 10-hour, 1 continuing education unit credit course on rescue robotics has been created and is available. Rescue robots and sensors are available for loan upon request.

Restructuring within an academic health center to support quality and safety: the development of the Center for Quality and Safety at the Massachusetts General Hospital.

PubMed

Bohmer, Richard M J; Bloom, Jonathan D; Mort, Elizabeth A; Demehin, Akinluwa A; Meyer, Gregg S

2009-12-01

Recent focus on the need to improve the quality and safety of health care has created new challenges for academic health centers (AHCs). Whereas previously quality was largely assumed, today it is increasingly quantifiable and requires organized systems for improvement. Traditional structures and cultures within AHCs, although well suited to the tripartite missions of teaching, research, and clinical care, are not easily adaptable to the tasks of measuring, reporting, and improving quality. Here, the authors use a case study of Massachusetts General Hospital's efforts to restructure quality and safety to illustrate the value of beginning with a focus on organizational culture, using a systematic process of engaging clinical leadership, developing an organizational framework dependent on proven business principles, leveraging focus events, and maintaining executive dedication to execution of the initiative. The case provides a generalizable example for AHCs of how applying explicit management design can foster robust organizational change with relatively modest incremental financial resources.

Sandia National Laboratories: Research

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

The operating room of the future: white paper summation.

PubMed

Moses, Gerald R; Farr, James O

2003-01-01

On November 8 and 9, 2001, leading experts in patient safety, medical informatics, advanced surgical devices, telesurgery, and surgical facilities met to formulate strategic directions for the "OR of the Future" in both military and civilian healthcare. The meeting was co-hosted by the Telemedicine and Advanced Technology Research Center (TATRC) part of the U.S. Army Medical Research and Materiel Command at Fort Detrick, and the University of Maryland Medical Center. Researchers, surgeons, and experts in the field of operating room (OR) technology addressed the current state of research and technological developments. Experts in (1) patient safety, (2) medical informatics, (3) advanced surgical devices, (4) telesurgery, and (5) surgical facilities met in focused work groups to develop a proposed research agenda for each content area. Afterwards, each focused group agreed to develop a 'White Paper' on each specific area, addressing the current and future prospectus. In addition, they attempted to provide a recommended research roadmap for the 'OR of the Future.'

Evaluation of Education and Outreach Methods and Strategies - A Case Study of a Web-Based Rail Safety Education Initiative

DOT National Transportation Integrated Search

2014-04-01

The U. S. Department of Transportations (U.S. DOT) Research and Innovative Technology Administrations (RITA) John A. Volpe National Transportation Systems Center (Volpe Center), under the direction of the U.S. DOT Federal Railroad Administratio...

A Model of Low Grazing Angle Sea Clutter for Coherent Radar Performance Analysis

DTIC Science & Technology

2013-06-01

Navy Communications & Information Warfare Doc. Data Sheet Director General Navy Certification and Safety Doc. Data Sheet Director General Submarine...Abstracts, US 1 Documents Librarian , The Center for Research Libraries, US 1 International Technology and Science Center (ITSC) Library 1 Spare Copies 4

[Study of post marketing safety reevaluation of shenqi fuzheng injection].

PubMed

Ai, Qing-Hua; Li, Yuan-Yuan; Xie, Yan-Ming

2014-09-01

In order to promote the Shenqifuzheng injection (SQFZ) clinical medication safety, this study reevaluate on SQFZ post marketing safety study systematically. Including multi center large sample registration type safety monitoring research, the analysis based on national spontaneous reporting system data, the analysis based on the 20 national hospital information system data and literature research. Above the analysis, it suggests that SQFZ has good security. The more adverse drug reaction (ADR) as allergic reactions, mainly involved in the damage of skin, appendages and its systemic damage, serious person can appear allergic shock. ADR/E is more common in the elderly, may be related to medication (tumor) populations. Early warning analysis based on SRS data and literature research are of the view that "phlebitis" has a strong association with SQFZ used.

Proposal for continued research in intelligent machines at the Center for Engineering Systems Advanced Research (CESAR) for FY 1988 to FY 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weisbin, C.R.

1987-03-01

This document reviews research accomplishments achieved by the staff of the Center for Engineering Systems Advanced Research (CESAR) during the fiscal years 1984 through 1987. The manuscript also describes future CESAR objectives for the 1988-1991 planning horizon, and beyond. As much as possible, the basic research goals are derived from perceived Department of Energy (DOE) needs for increased safety, productivity, and competitiveness in the United States energy producing and consuming facilities. Research areas covered include the HERMIES-II Robot, autonomous robot navigation, hypercube computers, machine vision, and manipulators.

Urban construction and safety project

NASA Technical Reports Server (NTRS)

Hogarth, P. T.

1976-01-01

Technology utilization projects in the area of urban construction and safety included the following: development of undercarpet and baseboard flat conductor cables, flood insurance studies, tornado safety engineering, the Project TECH house at the Langley Research Center, assistance to the City of Atlanta in their environmental habitability and resource allocation program, and market assessment of a solid state diesel engine controller. The flat conductor cable and the flood insurance studies are given particular attention.

The NHTSA & NCSDR program to combat drowsy driving : a report to the House and Senate Appropriations Committees describing collaboration between National Highway Traffic Safety Administration and National Center on Sleep Disorders Research, National Heart, Lung and Blood Institute, National Institutes of Health

DOT National Transportation Integrated Search

1999-03-15

In 1996, the National Highway Traffic Safety Administration (NHTSA) embarked on a congressionally mandated effort to develop educational countermeasures to the effects of fatigue, sleep disorders, and inattention on highway safety. In collaboration w...

2001 Research Reports NASA/ASEE Summer Faculty Fellowship Program

NASA Technical Reports Server (NTRS)

2001-01-01

This document is a collection of technical reports on research conducted by the participants in the 2001 NASA/ASEE Summer Faculty Fellowship Program at the Kennedy Space Center (KSC). Research areas are broad. Some of the topics addressed include: project management, space shuttle safety risks induced by human factor errors, body wearable computers as a feasible delivery system for 'work authorization documents', gas leak detection using remote sensing technologies, a history of the Kennedy Space Center, and design concepts for collabsible cyrogenic storage vessels.

Development of the Sealzall Machine : Upgrade to the TTLS (Pavement Crack Sealer)

DOT National Transportation Integrated Search

2009-10-31

The AHMCT Research Center, together with Caltrans, has been leading a multi-year research effort to develop : innovative high production crack sealing equipment, which improves safety while reducing costs. The Sealzall : Machine development project i...

Sandia National Laboratories: Visiting Research Scholars

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Sandia National Laboratories: Research: Biodefense

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Sandia National Laboratories: Research: Bioscience

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Evaluating the appropriate level of service for Michigan rest areas and welcome centers considering safety and economic factors.

DOT National Transportation Integrated Search

2012-04-30

Research was performed to determine the value of public rest areas in Michigan, including welcome : centers. A benefit/cost (B/C) economic analysis procedure was utilized to assess rest areas both : individually and as a system. The benefits associat...

The safety and physiologic effects of the anticoccidial drugs monensin and clazuril in sandhill cranes (Grus canadensis)

USGS Publications Warehouse

Carpenter, J.W.; Novilla, M.N.; Hatfield, J.S.

1992-01-01

Because crane chick mortality from disseminated visceral coccidiosis (DVC) at the Patuxent Wildlife Research Center increased in 1988, suggesting that the parasite may be developing a resistance to amprolium, a target animal safety study using coccidiostats, monensin and clazuril, was conducted on 27 subadult sandhill cranes.

Food safety concerns in the U.S. and research on Shiga Toxin-producing E. coli

USDA-ARS?s Scientific Manuscript database

In the U.S., there are several government agencies that deal with food safety. Under the Department of Health and Human Services, there are the Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC). The CDC collaborates with state agencies, private organizatio...

Career Profile: Flight Operations Engineer (Airborne Science) Matthew Berry

NASA Image and Video Library

2014-11-05

Operations engineers at NASA's Armstrong Flight Research Center help to advance science, technology, aeronautics, and space exploration by managing operational aspects of a flight research project. They serve as the governing authority on airworthiness related to the modification, operation, or maintenance of specialized research or support aircraft so those aircraft can be flown safely without jeopardizing the pilots, persons on the ground or the flight test project. With extensive aircraft modifications often required to support new research and technology development efforts, operations engineers are key leaders from technical concept to flight to ensure flight safety and mission success. Other responsibilities of an operations engineer include configuration management, performing systems design and integration, system safety analysis, coordinating flight readiness activities, and providing real-time flight support. This video highlights the responsibilities and daily activities of NASA Armstrong operations engineer Matthew Berry during the preparation and execution of flight tests in support of aeronautics research. http://www.nasa.gov/centers/armstrong/home/ http://www.nasa.gov/

Career Profile: Flight Operations Engineer (Aeronautics) Brian Griffin

NASA Image and Video Library

2014-10-17

Operations engineers at NASA's Armstrong Flight Research Center help to advance science, technology, aeronautics, and space exploration by managing operational aspects of a flight research project. They serve as the governing authority on airworthiness related to the modification, operation, or maintenance of specialized research or support aircraft so those aircraft can be flown safely without jeopardizing the pilots, persons on the ground or the flight test project. With extensive aircraft modifications often required to support new research and technology development efforts, operations engineers are key leaders from technical concept to flight to ensure flight safety and mission success. Other responsibilities of an operations engineer include configuration management, performing systems design and integration, system safety analysis, coordinating flight readiness activities, and providing real-time flight support. This video highlights the responsibilities and daily activities of NASA Armstrong operations engineer Brian Griffin during the preparation and execution of flight tests in support of aeronautics research. http://www.nasa.gov/centers/armstrong/home/ http://www.nasa.gov/

Patient Safety Center Organization

DTIC Science & Technology

2006-06-01

Enterectomy Bariatric 7/20/05 4 hours/course (28 hours/year) Surgery R 7 Dr. Karen Horvath R5 Lap Enterectomy & Colectomy 11/30/05 4...areas in the UW Schools of Nursing and Dentistry, at the Harborview Research Center Microvascular Surgery lab, with the Seattle Children’s Hospital and...1 laboratory complex (2500 sq ft) has been designed within the University of Washington Medical Center, in the Surgery Pavilion complex

The Armstrong Institute: An Academic Institute for Patient Safety and Quality Improvement, Research, Training, and Practice.

PubMed

Pronovost, Peter J; Holzmueller, Christine G; Molello, Nancy E; Paine, Lori; Winner, Laura; Marsteller, Jill A; Berenholtz, Sean M; Aboumatar, Hanan J; Demski, Renee; Armstrong, C Michael

2015-10-01

Academic medical centers (AMCs) could advance the science of health care delivery, improve patient safety and quality improvement, and enhance value, but many centers have fragmented efforts with little accountability. Johns Hopkins Medicine, the AMC under which the Johns Hopkins University School of Medicine and the Johns Hopkins Health System are organized, experienced similar challenges, with operational patient safety and quality leadership separate from safety and quality-related research efforts. To unite efforts and establish accountability, the Armstrong Institute for Patient Safety and Quality was created in 2011.The authors describe the development, purpose, governance, function, and challenges of the institute to help other AMCs replicate it and accelerate safety and quality improvement. The purpose is to partner with patients, their loved ones, and all interested parties to end preventable harm, continuously improve patient outcomes and experience, and eliminate waste in health care. A governance structure was created, with care mapped into seven categories, to oversee the quality and safety of all patients treated at a Johns Hopkins Medicine entity. The governance has a Patient Safety and Quality Board Committee that sets strategic goals, and the institute communicates these goals throughout the health system and supports personnel in meeting these goals. The institute is organized into 13 functional councils reflecting their behaviors and purpose. The institute works daily to build the capacity of clinicians trained in safety and quality through established programs, advance improvement science, and implement and evaluate interventions to improve the quality of care and safety of patients.

Development of the Sealzall Machine : upgrade to the TTLS (pavement crack sealer).

DOT National Transportation Integrated Search

2009-10-01

The AHMCT Research Center, together with Caltrans, has been leading a multi-year research effort to develop innovative high production crack sealing equipment, which improves safety while reducing costs. The Sealzall Machine development project is th...

77 FR 11625 - Child Restraint Systems

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-27

...),'' Stammen; Vehicle Research and Test Center, National Highway Traffic Safety Administration (September 2004... exceeded. However, during extensive post-NPRM booster seat testing, inconsistencies in the test protocol... substantial rulemaking and research efforts to try to address test variability. NHTSA investigated the ATD's...

A Milestone of aeromedical research contributions to civil aviation safety : the 1000th report in the CARI/OAM series : final report.

DOT National Transportation Integrated Search

2005-03-01

A historical, largely photographic retrospective is presented in recognition of the 1000th published report emanating from the FAA aeromedical research center officially established as the Civil Aeromedical Research Institute (CARI) in August 1960. T...

Food safety research at Delaware State University: keeping the runs from slowing you down

USDA-ARS?s Scientific Manuscript database

For more than a decade, the USDA ARS Center of Excellence located within the Delaware State University College of Agriculture and Related Sciences has been focused on foodborne virus research with special emphasis on bivalve shellfish. Research accomplishments include: 1) development of expedient e...

January, 2018 Mission Success is in Our Hands.

NASA Image and Video Library

2018-01-18

Vernon "Bill" Wessel, former associate director of NASA's Glenn Research Center from 2006-2011, addresses team members at NASA's Marshall Space Flight Center Jan. 19 as part of the "Mission Success in in Our Hands" Shared Experiences forum. Wessel, currently senior vice president of Ares Corp. and deputy of the Huntsville-based company's Space & Defense Division, spoke about his 30-year NASA career and the importance of workplace safety. "Keep in your head every day and in every way that safety is number one," he said. "When you meet people, ask them, 'How are you doing today? How's the job? How are you staying safe?' These are the things that are important." The bimonthly Shared Experiences forum, a Marshall safety initiative to promote and strengthen mission assurance and flight safety, is sponsored by NASA partner Jacobs Engineering of Huntsville.

Microgravity Experiments Safety and Integration Requirements Document Tree

NASA Technical Reports Server (NTRS)

Hogan, Jean M.

1995-01-01

This report is a document tree of the safety and integration documents required to develop a space experiment. Pertinent document information for each of the top level (tier one) safety and integration documents, and their applicable and reference (tier two) documents has been identified. This information includes: document title, revision level, configuration management, electronic availability, listed applicable and reference documents, source for obtaining the document, and document owner. One of the main conclusions of this report is that no single document tree exists for all safety and integration documents, regardless of the Shuttle carrier. This document also identifies the need for a single point of contact for customers wishing to access documents. The data in this report serves as a valuable information source for the NASA Lewis Research Center Project Documentation Center, as well as for all developers of space experiments.

Mitigation of Oil in Water Column: Mitigation Prototype Tests

DTIC Science & Technology

2017-06-01

distribution is unlimited. The study was funded in part by the U.S. Department of the Interior, Bureau of Safety and Environmental Enforcement (BSEE) through...James E. Fletcher Environment &Waterways Branch Chief United States Coast Guard Research & Development Center 1 Chelsea Street New London, CT...Research and Development Center 1 Chelsea Street New London, CT 06320 10. Work Unit No. (TRAIS) 11. Contract or Grant No. Task Order #HSCG32-17-J

NASA Software Safety Standard

NASA Technical Reports Server (NTRS)

Rosenberg, Linda

1997-01-01

If software is a critical element in a safety critical system, it is imperative to implement a systematic approach to software safety as an integral part of the overall system safety programs. The NASA-STD-8719.13A, "NASA Software Safety Standard", describes the activities necessary to ensure that safety is designed into software that is acquired or developed by NASA, and that safety is maintained throughout the software life cycle. A PDF version, is available on the WWW from Lewis. A Guidebook that will assist in the implementation of the requirements in the Safety Standard is under development at the Lewis Research Center (LeRC). After completion, it will also be available on the WWW from Lewis.

46 CFR 50.10-23 - Marine Safety Center.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Marine Safety Center. 50.10-23 Section 50.10-23 Shipping... Definition of Terms Used in This Subchapter § 50.10-23 Marine Safety Center. The term Marine Safety Center refers to the Commanding Officer, U.S. Coast Guard Marine Safety Center, 1900 Half Street, SW., Suite...

76 FR 46814 - Medicare Program; Evaluation Criteria and Standards for Quality Improvement Program Contracts...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-03

... Work) The Patient Safety initiatives are designed to help achieve the goals of improving individual... coordinating center, the Center for Medicare and Medicaid Innovation, and the Agency for Healthcare Research... outreach activities required to complete all Aims of the 10th SOW successfully. The CRISP Model is designed...

Haimei Zheng

Science.gov Websites

Investigators Division Staff Facilities and Centers Staff Jobs Safety Personnel Resources Committees In Case of ; Finance Templates Travel One-Stop Investigators Division Staff Facilities and Centers Staff Jobs Haimei Zheng Staff Scientist hmzheng@lbl.gov 510-486-4110 Research profile » A U.S. Department of Energy

Data Mining Tools Make Flights Safer, More Efficient

NASA Technical Reports Server (NTRS)

2014-01-01

A small data mining team at Ames Research Center developed a set of algorithms ideal for combing through flight data to find anomalies. Dallas-based Southwest Airlines Co. signed a Space Act Agreement with Ames in 2011 to access the tools, helping the company refine its safety practices, improve its safety reviews, and increase flight efficiencies.

New clinical trial opens to determine safety and efficacy of PROSTVAC, nivolumab and ipilimumab in men with localized prostate cancer | Center for Cancer Research

Cancer.gov

A new study is now open to evaluate the safety and effectiveness of a treatment regimen that combines PROSTVAC with ipilimumab and/or nivolumab in men with localized prostate cancer who have elected to undergo surgical resection (prostatectomy).  Learn more...

Safety and tolerability of combination therapy vs. standard treatment alone for patients with previously treated non-small cell lung cancer | Center for Cancer Research

Cancer.gov

Dr. James Gulley is leading a team to test the safety and tolerability of the combination of nivolumab and CV301 to see if it can improve the survival for patientis with metastatic non-small cell lung cancer.  Learn more...

78 FR 45930 - Guidance for Industry: Safety Labeling Changes-Implementation of Section 505(o)(4) of the Federal...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-30

...] Guidance for Industry: Safety Labeling Changes--Implementation of Section 505(o)(4) of the Federal Food...: The Food and Drug Administration (FDA) is announcing the availability of a guidance for industry..., Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51...

Criticality Safety Evaluation of the LLNL Inherently Safe Subcritical Assembly (ISSA)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Percher, Catherine

2012-06-19

The LLNL Nuclear Criticality Safety Division has developed a training center to illustrate criticality safety and reactor physics concepts through hands-on experimental training. The experimental assembly, the Inherently Safe Subcritical Assembly (ISSA), uses surplus highly enriched research reactor fuel configured in a water tank. The training activities will be conducted by LLNL following the requirements of an Integration Work Sheet (IWS) and associated Safety Plan. Students will be allowed to handle the fissile material under the supervision of LLNL instructors. This report provides the technical criticality safety basis for instructional operations with the ISSA experimental assembly.

Translating Health Care–Associated Urinary Tract Infection Prevention Research into Practice via the Bladder Bundle

PubMed Central

Saint, Sanjay; Olmsted, Russell N.; Fakih, Mohamad G.; Kowalski, Christine P.; Watson, Sam R.; Sales, Anne E.; Krein, Sarah L.

2009-01-01

Article-at-a-Glance Background: Catheter-associated urinary tract infection (CAUTI), a frequent health care–associated infection (HAI), is a costly and common condition resulting in patient discomfort, activity restriction, and hospital discharge delays. The Centers for Medicare & Medicaid Services (CMS) no longer reimburses hospitals for the extra cost of caring for patients who develop CAUTI. The Michigan Health and Hospital Association (MHA) Keystone Center for Patient Safety & Quality has initiated a statewide initiative, MHA Keystone HAI, to help ameliorate the burden of disease associated with indwelling catheterization. In addition, a long-term research project is being conducted to evaluate the current initiative and to identify practical strategies to ensure the effective use of proven infection prevention and patient safety practices. Overview of the Bladder Bundle Initiative in Michigan: The bladder bundle as conceived by MHA Keystone HAI focuses on preventing CAUTI by optimizing the use of urinary catheters with a specific emphasis on continual assessment and catheter removal as soon as possible, especially for patients without a clear indication. Collaboration Between Researchers and State wide Patient Safety Organizations: A synergistic collaboration between patient safety researchers and a statewide patient safety organization is aimed at identifying effective strategies to move evidence from peer-reviewed literature to the bedside. Practical strategies that facilitate implementation of the bundle will be developed and tested using mixed quantitative and qualitative methods. Discussion: Simply disseminating scientific evidence is often ineffective in changing clinical practice. Therefore, learning how to implement these findings is critically important to promoting high-quality care and a safe health care environment. PMID:19769204

75 FR 4407 - Science Board to the Food and Drug Administration; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-27

... subcommittee reviewing research at the Center for Food Safety and Applied Nutrition. The Science Board will... appropriate research agenda, and on upgrading its scientific and research facilities to keep pace with these... scientific research programs. Date and Time: The meeting will be held on Monday, February 22, 2010, from 8 a...

The United States Does CAIR About Cultural Safety: Examining Cultural Safety Within Indigenous Health Contexts in Canada and the United States.

PubMed

Darroch, Francine; Giles, Audrey; Sanderson, Priscilla; Brooks-Cleator, Lauren; Schwartz, Anna; Joseph, Darold; Nosker, Roger

2017-05-01

This article examines the concept and use of the term cultural safety in Canada and the United States. To examine the uptake of cultural awareness, cultural sensitivity, cultural competence, and cultural safety between health organizations in Canada and the United States, we reviewed position statements/policies of health care associations. The majority of selected health associations in Canada include cultural safety within position statements or organizational policies; however, comparable U.S. organizations focused on cultural sensitivity and cultural competence. Through the work of the Center for American Indian Resilience, we demonstrate that U.S. researchers engage with the tenets of cultural safety-despite not using the language. We recommend that health care providers and health researchers consider the tenets of cultural safety. To address health disparities between American Indian populations and non-American Indians, we urge the adoption of the term and tenets of cultural safety in the United States.

Human performance cognitive-behavioral modeling: a benefit for occupational safety.

PubMed

Gore, Brian F

2002-01-01

Human Performance Modeling (HPM) is a computer-aided job analysis software methodology used to generate predictions of complex human-automation integration and system flow patterns with the goal of improving operator and system safety. The use of HPM tools has recently been increasing due to reductions in computational cost, augmentations in the tools' fidelity, and usefulness in the generated output. An examination of an Air Man-machine Integration Design and Analysis System (Air MIDAS) model evaluating complex human-automation integration currently underway at NASA Ames Research Center will highlight the importance to occupational safety of considering both cognitive and physical aspects of performance when researching human error.

Human performance cognitive-behavioral modeling: a benefit for occupational safety

NASA Technical Reports Server (NTRS)

Gore, Brian F.

2002-01-01

Human Performance Modeling (HPM) is a computer-aided job analysis software methodology used to generate predictions of complex human-automation integration and system flow patterns with the goal of improving operator and system safety. The use of HPM tools has recently been increasing due to reductions in computational cost, augmentations in the tools' fidelity, and usefulness in the generated output. An examination of an Air Man-machine Integration Design and Analysis System (Air MIDAS) model evaluating complex human-automation integration currently underway at NASA Ames Research Center will highlight the importance to occupational safety of considering both cognitive and physical aspects of performance when researching human error.

Veterinary pharmacovigilance in India: A need of hour.

PubMed

Kumar, Rishi; Kalaiselvan, Vivekanandan; Verma, Ravendra; Kaur, Ismeet; Kumar, Pranay; Singh, G N

2017-01-01

Veterinary pharmacovigilance (PV) is important for the Medicine which are used for treating disease in animals. It becomes more important when these animals are further used for producing food. Adverse drug reactions (ADRs) have a direct impact on animals and indirect impact on human beings, for example, through milk products, other animal producing food products. Currently, PV program of India is playing a vital role in assessing the safety of medicines in Indian Population. The safety of medicine in animals can be assessed by veterinary PV. The research institutes involved in animal research and veterinary hospitals can be considered as ADR monitoring centers to assess the safety of medicines on animals.

Flights of Discovery: 50 Years at the NASA Dryden Flight Research Center

NASA Technical Reports Server (NTRS)

Wallace, Lance E.

1996-01-01

As part of the NASA History Series, this report (NASA SP-4309) describes fifty years of aeronautical research at the NASA Dryden Flight Research Center. Starting with early efforts to exceed the speed of sound with the X-1 aircraft, and continuing through to the X-31 research aircraft, the report covers the flight activities of all of the major research aircraft and lifting bodies studied by NASA. Chapter One, 'A Place for Discovery', describes the facility itself and the surrounding Mojave Desert. Chapter Two, 'The Right Stuff', is about the people involved in the flight research programs. Chapter Three, 'Higher, Faster' summarizes the early years of transonic flight testing and the development of several lifting bodies. Chapter Four, 'Improving Efficiency, Maneuverability & Systems', outlines the development of aeronautical developments such as the supercritical wing, the mission adaptive wing, and various techniques for improving maneuverability fo winged aircraft. Chapter 5, 'Supporting National Efforts', shows how the research activities carried out at Dryden fit into NASA's programs across the country in supporting the space program, in safety and in problem solving related to aircraft design and aviation safety in general. Chapter Six, ' Future Directions' looks to future research building on the fifty year history of aeronautical research at the Dryden Flight Research Center. A glossary of acronyms and an appendix covering concepts and innovations are included. The report also contains many photographs providing a graphical perspective to the historical record.

Development of the Runway Incursion Advisory and Alerting System (RIAAS): Research Summary

NASA Technical Reports Server (NTRS)

Jones, Denise R. (Technical Monitor); Cassell, Rick

2005-01-01

This report summarizes research conducted on an aircraft based Runway Incursion Advisory and Alerting System (RIAAS) developed under a cooperative agreement between Rannoch Corporation and the NASA Langley Research Center. A summary of RIAAS is presented along with results from simulation and flight testing, safety benefits, and key technical issues.

Human Systems Integration at NASA Ames Research Center

NASA Technical Reports Server (NTRS)

McCandless, Jeffrey

2017-01-01

The Human Systems Integration Division focuses on the design and operations of complex aerospace systems through analysis, experimentation and modeling. With over a dozen labs and over 120 people, the division conducts research to improve safety, efficiency and mission success. Areas of investigation include applied vision research which will be discussed during this seminar.

Knowledge management: Role of the the Radiation Safety Information Computational Center (RSICC)

NASA Astrophysics Data System (ADS)

Valentine, Timothy

2017-09-01

The Radiation Safety Information Computational Center (RSICC) at Oak Ridge National Laboratory (ORNL) is an information analysis center that collects, archives, evaluates, synthesizes and distributes information, data and codes that are used in various nuclear technology applications. RSICC retains more than 2,000 software packages that have been provided by code developers from various federal and international agencies. RSICC's customers (scientists, engineers, and students from around the world) obtain access to such computing codes (source and/or executable versions) and processed nuclear data files to promote on-going research, to ensure nuclear and radiological safety, and to advance nuclear technology. The role of such information analysis centers is critical for supporting and sustaining nuclear education and training programs both domestically and internationally, as the majority of RSICC's customers are students attending U.S. universities. Additionally, RSICC operates a secure CLOUD computing system to provide access to sensitive export-controlled modeling and simulation (M&S) tools that support both domestic and international activities. This presentation will provide a general review of RSICC's activities, services, and systems that support knowledge management and education and training in the nuclear field.

Health care work environments, employee satisfaction, and patient safety: Care provider perspectives.

PubMed

Rathert, Cheryl; May, Douglas R

2007-01-01

Experts continue to decry the lack of progress made in decreasing the alarming frequency of medical errors in health care organizations (Leape, L. L., & Berwick, D. M. (2005). Five years after to err is human: What have we learned?. Journal of the American Medical Association, 293(19), 2384-2390). At the same time, other experts are concerned about the lack of job satisfaction and turnover among nurses (. Keeping patients safe: Transforming the work environment of nurses. Washington, DC: National Academy Press). Research and theory suggest that a work environment that facilitates patient-centered care should increase patient safety and nurse satisfaction. The present study began with a conceptual model that specifies how work environment variables should be related to both nurse and patient outcomes. Specifically, we proposed that health care work units with climates for patient-centered care should have nurses who are more satisfied with their jobs. Such units should also have higher levels of patient safety, with fewer medication errors. We examined perceptions of nurses from three acute care hospitals in the eastern United States. Nurses who perceived their work units as more patient centered were significantly more satisfied with their jobs than were those whose units were perceived as less patient centered. Those whose work units were more patient centered reported that medication errors occurred less frequently in their units and said that they felt more comfortable reporting errors and near-misses than those in less patient-centered units. Patients and quality leaders continue to call for delivery of patient-centered care. If climates that facilitate such care are also related to improved patient safety and nurse satisfaction, proactive, patient-centered management of the work environment could result in improved patient, employee, and organizational outcomes.

Pilot Ed Lewis with T-34C aircraft on ramp

NASA Image and Video Library

1998-03-04

NASA pilot Ed Lewis with the T-34C aircraft on the Dryden Flight Research Center Ramp. The aircraft was previously used at the Lewis Research Center in propulsion experiments involving turboprop engines, and was used as a chase aircraft at Dryden for smaller and slower research projects. Chase aircraft accompany research flights for photography and video purposes, and also as support for safety and research. At Dryden, the T-34 is used mainly for smaller remotely piloted vehicles which fly slower than NASA's F-18's, used for larger scale projects. This aircraft was returned to the U.S. Navy in May of 2002.

International Conference on Harmonisation; Electronic Transmission of Postmarket Individual Case Safety Reports for Drugs and Biologics, Excluding Vaccines; Availability of Food and Drug Administration Regional Implementation Specifications for ICH E2B(R3) Reporting to the Food and Drug Administration Adverse Event Reporting System. Notice of Availability.

PubMed

2016-06-23

The Food and Drug Administration (FDA) is announcing the availability of its FDA Adverse Event Reporting System (FAERS) Regional Implementation Specifications for the International Conference on Harmonisation (ICH) E2B(R3) Specification. FDA is making this technical specifications document available to assist interested parties in electronically submitting individual case safety reports (ICSRs) (and ICSR attachments) to the Center for Drug Evaluation and Research (CDER) and the Center for Biologics Evaluation and Research (CBER). This document, entitled "FDA Regional Implementation Specifications for ICH E2B(R3) Implementation: Postmarket Submission of Individual Case Safety Reports (ICSRs) for Drugs and Biologics, Excluding Vaccines" supplements the "E2B(R3) Electronic Transmission of Individual Case Safety Reports (ICSRs) Implementation Guide--Data Elements and Message Specification" final guidance for industry and describes FDA's technical approach for receiving ICSRs, for incorporating regionally controlled terminology, and for adding region-specific data elements when reporting to FAERS.

Alex Pines

Science.gov Websites

@berkeley.edu 510-642-1220 Research profile » A U.S. Department of Energy National Laboratory Operated by the Computational Study of Excited-State Phenomena in Energy Materials Center for X-ray Optics MSD Facilities Ion Investigators Division Staff Facilities and Centers Staff Jobs Safety Personnel Resources Committees In Case of

Clinical trial shows safety and effectiveness of new combination immunotherapy for advanced liver cancer | Center for Cancer Research

Cancer.gov

A recently completed phase I clinical trial at the NIH Clinical Center in Bethesda, Maryland, demonstrates that a combination of two immunotherapy drugs to target hepatocellular carcinoma (HCC) was well-tolerated and shrunk tumors in a larger percentage of patients than the standard monotherapy.  Read more...

Indiana crash facts 2008

DOT National Transportation Integrated Search

2008-01-01

Designing and implementing effective traffic safety policies : requires data-driven analysis of traffic collisions. To help in the : policy-making process, the Indiana University Public Policy : Institute, Center for Criminal Justice Research (CCJR o...

Indiana crash facts 2006

DOT National Transportation Integrated Search

2006-01-01

Designing and implementing effective traffic safety policies : requires data-driven analysis of traffic collisions. To help in the : policy-making process, the Indiana University Public Policy : Institute, Center for Criminal Justice Research (CCJR o...

Indiana crash facts 1998

DOT National Transportation Integrated Search

1998-01-01

Designing and implementing effective traffic safety policies : requires data-driven analysis of traffic collisions. To help in the : policy-making process, the Indiana University Public Policy : Institute, Center for Criminal Justice Research (CCJR o...

Indiana crash facts 2007

DOT National Transportation Integrated Search

2007-01-01

Designing and implementing effective traffic safety policies : requires data-driven analysis of traffic collisions. To help in the : policy-making process, the Indiana University Public Policy : Institute, Center for Criminal Justice Research (CCJR o...

The occupational safety of health professionals working at community and family health centers.

PubMed

Ozturk, Havva; Babacan, Elif

2014-10-01

Healthcare professionals encounter many medical risks while providing healthcare services to individuals and the community. Thus, occupational safety studies are very important in health care organizations. They involve studies performed to establish legal, technical, and medical measures that must be taken to prevent employees from sustaining physical or mental damage because of work hazards. This study was conducted to determine if the occupational safety of health personnel at community and family health centers (CHC and FHC) has been achieved. The population of this cross-sectional study comprised 507 nurses, 199 physicians, and 237 other medical personnel working at a total of 18 family health centers (FHC) and community health centers (CHC) in Trabzon, Turkey. The sample consisted of a total of 418 nurses, 156 physicians, and 123 other medical personnel. Sampling method was not used, and the researchers tried to reach the whole population. Data were gathered with the Occupational Safety Scale (OSS) and a questionnaire regarding demographic characteristics and occupational safety. According to the evaluations of all the medical personnel, the mean ± SD of total score of the OSS was 3.57 ± 0.98; of the OSS's subscales, the mean ± SD of the health screening and registry systems was 2.76 ± 1.44, of occupational diseases and problems was 3.04 ± 1.3 and critical fields control was 3.12 ± 1.62. In addition, occupational safety was found more insufficient by nurses (F = 14.18; P < 0.001). All healthcare personnel, particularly nurses working in CHCs and FHCs found occupational safety to be insufficient as related to protective and supportive activities.

Renewable energy and occupational health and safety research directions: a white paper from the Energy Summit, Denver Colorado, April 11-13, 2011.

PubMed

Mulloy, Karen B; Sumner, Steven A; Rose, Cecile; Conway, George A; Reynolds, Stephen J; Davidson, Margaret E; Heidel, Donna S; Layde, Peter M

2013-11-01

Renewable energy production may offer advantages to human health by way of less pollution and fewer climate-change associated ill-health effects. Limited data suggests that renewable energy will also offer benefits to workers in the form of reduced occupational injury, illness and deaths. However, studies of worker safety and health in the industry are limited. The Mountain and Plains Education and Research Center (MAP ERC) Energy Summit held in April 2011 explored issues concerning worker health and safety in the renewable energy industry. The limited information on hazards of working in the renewable energy industry emphasizes the need for further research. Two basic approaches to guiding both prevention and future research should include: (1) applying lessons learned from other fields of occupational safety and health, particularly the extractive energy industry; and (2) utilizing knowledge of occupational hazards of specific materials and processes used in the renewable energy industry. © 2013 Wiley Periodicals, Inc.

Possible safety hazards associated with the operation of the 0.3-m transonic cryogenic tunnel at the NASA Langley Research Center

NASA Technical Reports Server (NTRS)

Webster, T. J.

1982-01-01

The 0.3 m Transonic Cryogenic Tunnel (TCT) at the NASA Langley Research Center was built in 1973 as a facility intended to be used for no more than 60 hours in order to verify the validity of the cryogenic wind tunnel concept at transonic speeds. The role of the 0.3 m TCT has gradually changed until now, after over 3000 hours of operation, it is classified as a major NASA research facility and, under the administration of the Experimental Techniques Branch, it is used extensively for the testing of airfoils at high Reynolds numbers and for the development of various technologies related to the efficient operation and use of cryogenic wind tunnels. The purpose of this report is to document the results of a recent safety analysis of the 0.3 m TCT facility. This analysis was made as part of an on going program with the Experimental Techniques Branch designed to ensure that the existing equipment and current operating procedures of the 0.3 m TCT facility are acceptable in terms of today's standards of safety for cryogenic systems.

Space Operations Center system analysis study extension. Volume 4, book 2: SOC system analysis report

NASA Technical Reports Server (NTRS)

1982-01-01

The Space Operations Center (SOC) orbital space station research missions integration, crew requirements, SOC operations, and configurations are analyzed. Potential research and applications missions and their requirements are described. The capabilities of SOC are compared with user requirements. The SOC/space shuttle and shuttle-derived vehicle flight support operations and SOC orbital operations are described. Module configurations and systems options, SOC/external tank configurations, and configurations for geostationary orbits are described. Crew and systems safety configurations are summarized.

My Summer Experience as an Administrative Officer Assistant

NASA Technical Reports Server (NTRS)

Jones, Janelle C.

2004-01-01

The motto of the Safety and Assurance Directorate (SAAD) at NASA Glenn Research Center is "mission success starts with safety." SAAD has the functions of providing reliability, quality assurance, and system safety management to all GRC projects, programs and offices. Product assurance personnel within SAAD supervise the product assurance efforts by contractors on major contracts within GRC. The directorate includes five division offices and the Plum brook Decommissioning Office. SAAD oversees Glenn's Emergency Preparedness Program which handles security, hazmat, and disaster response and supervision.

Ozone Layer Protection

MedlinePlus

... Offices Labs and Research Centers Contact Us Share Ozone Layer Protection The stratospheric ozone layer is Earth’s “ ... to ozone-depleting substances, and sun safety. Stratospheric Ozone Layer Basic Ozone Layer Science Health and Environmental ...

42 CFR 88.14 - Standard for determining medical necessity.

Code of Federal Regulations, 2011 CFR

2011-10-01

... SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES WORLD TRADE CENTER HEALTH PROGRAM § 88.14 Standard for... which is reasonable and appropriate; based on scientific evidence, professional standards of care...

History of the Animal Care Program at Johnson Space Center

NASA Technical Reports Server (NTRS)

Khan-Mayberry, Noreen; Bassett, Stephanie

2010-01-01

NASA has a rich history of scientific research that has been conducted throughout our numerous manned spaceflight programs. This scientific research has included animal test subjects participating in various spaceflight missions, including most recently, Space Shuttle mission STS-131. The Animal Care Program at Johnson Space Center (JSC) in Houston, Texas is multi-faceted and unique in scope compared to other centers within the agency. The animal care program at JSC has evolved from strictly research to include a Longhorn facility and the Houston Zoo's Attwater Prairie Chicken refuge, which is used to help repopulate this endangered species. JSC is home to more than 300 species of animals including home of hundreds of white-tailed deer that roam freely throughout the center which pose unique issues in regards to population control and safety of NASA workers, visitors and tourists. We will give a broad overview of our day to day operations, animal research, community outreach and protection of animals at NASA Johnson Space Center.

Ensuring Payload Safety in Missions with Special Partnerships

NASA Technical Reports Server (NTRS)

Staubus, Calvert A.; Willenbring, Rachel C.; Blankenship, Michael D.

2016-01-01

The National Aeronautics and Space Administration (NASA) Expendable Launch Vehicle (ELV) payload space flight missions involve cooperative work between NASA and partners including spacecraft (or payload) contractors, universities, nonprofit research centers, Agency payload organization, Range Safety organization, Agency launch service organizations, and launch vehicle contractors. The role of NASA's Safety and Mission Assurance (SMA) Directorate is typically fairly straightforward, but when a mission's partnerships become more complex, to realize cost and science benefits (e.g., multi-agency payload(s) or cooperative international missions), the task of ensuring payload safety becomes much more challenging. This paper discusses lessons learned from NASA safety professionals working multiple-agency missions and offers suggestions to help fellow safety professionals working multiple-agency missions.

Spaceflight Safety on the North Coast of America

NASA Technical Reports Server (NTRS)

Ciancone, Michael L.; Havenhill, Maria T.; Terlep, Judith A.

1996-01-01

Spaceflight Safety (SFS) engineers at NASA Lewis Research Center (LeRC) are responsible for evaluating the microgravity fluids and combustion experiments, payloads and facilities developed at NASA LeRC which are manifested for spaceflight on the Space Shuttle, the Russian space station Mir, and/or the International Space Station (ISS). An ongoing activity at NASA LeRC is the comprehensive training of its SFS engineers through the creation and use of safety tools and processes. Teams of SFS engineers worked on the development of an Internet website (containing a spaceflight safety knowledge database and electronic templates of safety products) and the establishment of a technical peer review process (known as the Safety Assurance for Lewis Spaceflight Activities (SALSA) review).

Shared Decision Making in the Emergency Department: Development of a Policy-Relevant Patient-Centered Research Agenda

PubMed Central

Grudzen, Corita R.; Anderson, Jana R.; Carpenter, Christopher R.; Hess, Erik P.

2016-01-01

SUMMARY SDM in emergency medicine has the potential to improve the quality, safety, and outcomes of ED patients. Given that the ED is the gateway to care for patients with a variety of illnesses and injuries, SDM in the ED is relevant to numerous healthcare disciplines. We conducted a patient-centered one-day conference to define and develop a high-priority, timely research agenda. Participants included researchers, patients, stakeholder organizations, and content experts across many areas of medicine, health policy agencies, and federal and foundation funding organizations. The results of this conference published in this issue of Academic Emergency Medicine will provide an essential summary of the future research priorities for SDM to increase quality of care and patient-centered outcomes. PMID:27396583

The private funding of public research. New directions in the administration of occupational and environmental health research.

PubMed

Cullen, M R; Upton, A; Buffler, P; Robins, T; Schenker, M; Fine, L; Wiencek, R; Widess, E; Chiazze, L

1994-12-01

Dr. Cullen: The experience with the new research models, starting with the prototypic experience of the rubber industry studies of the 1970s and expanding to diverse sectors of American industry in the 1980s, has yielded some important lessons for the future. In closing this symposium I shall try to summarize these briefly. Certain strengths of the evolving process seem common to each of the models. Alone and collectively, the new research arrangements have quite apparently served to increase substantially the pool of funds available to the academic sector for the study of occupational health and safety problems. As a consequence, a larger pool of investigators has participated in the research process, greatly strengthening the future academic capability and experience of our fragilely supported teaching centers. Combined with the involvement of the academic centers in the review process, there has been an undeniable broadening and deepening of the nation's research output and long-term capability in occupational health. On the side of the private sector, the new relationships have led to marked progress in the knowledge base about health and safety problems, with a heavily directed focus on those of greatest relevance to the industries involved. The credibility of the knowledge acquired has been enhanced, an important achievement in a society in which perception of truth is often as important as the truth itself! Because of the requirements of the process for broad involvement by the organizations which undertake these activities, health and safety have achieved far greater visibility and attention by corporate and union leaders who may have previously had no involvement in issues of health and safety.(ABSTRACT TRUNCATED AT 250 WORDS)

Preventing accidents

DOT National Transportation Integrated Search

2005-08-01

As the most effective strategy for improving safety is to prevent accidents from occurring at all, the Volpe Center applies a broad range of research techniques and capabilities to determine causes and consequences of accidents and to identify, asses...

Alternative Fuels Data Center: Biodiesel Codes, Standards, and Safety

Science.gov Websites

Codes, Standards, and Safety to someone by E-mail Share Alternative Fuels Data Center: Biodiesel Codes, Standards, and Safety on Facebook Tweet about Alternative Fuels Data Center: Biodiesel Codes , Standards, and Safety on Twitter Bookmark Alternative Fuels Data Center: Biodiesel Codes, Standards, and

46 CFR 50.10-23 - Marine Safety Center.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 2 2014-10-01 2014-10-01 false Marine Safety Center. 50.10-23 Section 50.10-23 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING GENERAL PROVISIONS Definition of Terms Used in This Subchapter § 50.10-23 Marine Safety Center. The term Marine Safety Center...

46 CFR 50.10-23 - Marine Safety Center.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 2 2013-10-01 2013-10-01 false Marine Safety Center. 50.10-23 Section 50.10-23 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING GENERAL PROVISIONS Definition of Terms Used in This Subchapter § 50.10-23 Marine Safety Center. The term Marine Safety Center...

46 CFR 50.10-23 - Marine Safety Center.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 2 2011-10-01 2011-10-01 false Marine Safety Center. 50.10-23 Section 50.10-23 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING GENERAL PROVISIONS Definition of Terms Used in This Subchapter § 50.10-23 Marine Safety Center. The term Marine Safety Center...

46 CFR 50.10-23 - Marine Safety Center.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 2 2012-10-01 2012-10-01 false Marine Safety Center. 50.10-23 Section 50.10-23 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING GENERAL PROVISIONS Definition of Terms Used in This Subchapter § 50.10-23 Marine Safety Center. The term Marine Safety Center...

Regulatory concerns in the development of biologic-biomaterial combinations. United States Food and Drug Administration.

PubMed

Chapekar, M S

1996-01-01

Several biologic-biomaterial combinations are currently under development in an attempt to modulate tissue or organ function in patients. The FDA regulations on combination products and the intercenter agreements among the Center for Biologics Evaluation and Research (CBER), the Center for Devices and Radiological Health (CDRH), and the Center for Drugs Evaluation and Research (CDER) provide further guidance on center jurisdiction of combination products and other products where there are jurisdictional concerns. The biological component of biologic-biomaterial combinations raises a number of issues that relate to the safety and bioactivity of the final product. For example, transmission of adventitious agents to patients via somatic cells, tissue, or cell-derived products is a major safety concern as are in vivo inflammatory responses elicited by the biomaterial component. CBER has drafted a number of "Points to Consider" documents to provide further guidance in the development of biological products. The intent of this article is to provide the highlights of the FDA regulations for combination products and the intercenter agreement between CBER and CDRH delineating the responsibilities of each center for medical device activities. In addition, the article focuses on the CBER's concerns related to the development of somatic cell-biomaterial combinations for therapeutic use.

KSC-2012-1545

NASA Image and Video Library

2012-02-23

ORLANDO, Fla. -- The winners of NASA’s Quality and Safety Achievement Recognition, or QASAR, awards for 2011 pose for a group portrait during NASA’s ninth annual Project Management Challenge. From left are Teri Hamlin, Johnson Space Center Joseph B. Hamilton, Kennedy Space Center Francis “Frank” Merceret, Kennedy Space Center and Venki Venkat, Langley Research Center. Kennedy retiree Humberto "Bert" T. Garrido, not pictured, also received the award. NASA's QASAR award recognizes individual government and contractor employees who have demonstrated exemplary performance in contributing to the quality or safety of products, services, processes, or management programs and activities. PM Challenge 2012 was held at the Caribe Royale Hotel and Convention Center in Orlando, Fla., on February 22-23, to provide a forum for all stakeholders in the project management community to meet and share stories, lessons learned and new uses of technology in the industry. The PM Challenge is sponsored by NASA's Office of the Chief Engineer. For additional information, visit http://www.nasa.gov/offices/oce/pmchallenge/index.html. Photo credit: NASA/Jim Grossmann

Person-centered work environments, psychological safety, and positive affect in healthcare: a theoretical framework.

PubMed

Rathert, Cheryl; May, Douglas R

2008-01-01

We propose that in order to systematically improve healthcare quality, healthcare organizations (HCOs) need work environments that are person-centered: environments that support the careprovider as well as the patient. We further argue that HCOs have a moral imperative to provide a workplace where professional care standards can be achieved. We draw upon a large body of research from several disciplines to propose and articulate a theoretical framework that explains how the work environment should be related to the well-being of patients and careproviders, that is, the potential mediating mechanisms. Person-centered work environments include: 1. Climates for patient-centered care. 2. Climates for quality improvement. 3. Benevolent ethical climates. Such a work environment should support the provision of patient-centered care, and should lead to positive psychological states for careproviders, including psychological safety and positive affect. The model contributes to theory by specifying relationships between important organizational variables. The model can potentially contribute to practice by linking specific work environment attributes to outcomes for careproviders and patients.

Budget estimates: Fiscal year 1994. Volume 3: Research and program management

NASA Technical Reports Server (NTRS)

1994-01-01

The research and program management (R&PM) appropriation provides the salaries, other personnel and related costs, and travel support for NASA's civil service workforce. This FY 1994 budget funds costs associated with 23,623 full-time equivalent (FTE) work years. Budget estimates are provided for all NASA centers by categories such as space station and new technology investments, space flight programs, space science, life and microgravity sciences, advanced concepts and technology, center management and operations support, launch services, mission to planet earth, tracking and data programs, aeronautical research and technology, and safety, reliability, and quality assurance.

Advanced and recurring thymic carcinoma is target of new clinical trial | Center for Cancer Research

Cancer.gov

Adults diagnosed with thymic carcinoma who overexpress the protein mesothelin may be eligible to participate in a new clinical trial at the NIH Clinical Center. The study will look at the safety and effectiveness of an investigational drug, anetumab ravtansine, developed by Bayer HealthCare Pharmaceuticals. The drug works by binding to mesothelin, therefore overexpression of

Flight Test Approach to Adaptive Control Research

NASA Technical Reports Server (NTRS)

Pavlock, Kate Maureen; Less, James L.; Larson, David Nils

2011-01-01

The National Aeronautics and Space Administration s Dryden Flight Research Center completed flight testing of adaptive controls research on a full-scale F-18 testbed. The validation of adaptive controls has the potential to enhance safety in the presence of adverse conditions such as structural damage or control surface failures. This paper describes the research interface architecture, risk mitigations, flight test approach and lessons learned of adaptive controls research.

Funding and Strategic Alignment Guidance for Infusing Small Business Innovation Research Technology Into Aeronautics Research Mission Directorate Projects at NASA Glenn Research Center for 2015

NASA Technical Reports Server (NTRS)

Nguyen, Hung D.; Steele, Gynelle C.; Morris, Jessica R.

2015-01-01

This document is intended to enable the more effective transition of NASA Glenn Research Center (GRC) SBIR technologies funded by the Small Business Innovation Research (SBIR) program as well as its companion, the Small Business Technology Transfer (STTR) program into NASA Aeronautics Research Mission Directorate (ARMD) projects. Primarily, it is intended to help NASA program and project managers find useful technologies that have undergone extensive research and development (RRD), through Phase II of the SBIR program; however, it can also assist non-NASA agencies and commercial companies in this process. aviation safety, unmanned aircraft, ground and flight test technique, low emissions, quiet performance, rotorcraft

Geometric Design Laboratory Fact Sheet

DOT National Transportation Integrated Search

2006-08-02

This fact sheet provides concise information about the Geometric Design Laboratory (GDL) at the Turner-Fairbank Highway Research Center. The mission of the GDL is to provide technical support to the Federal Highway Administration's Office of Safety R...

Passenger vehicle crashes into stationary large trucks : incidence and possible countermeasures.

DOT National Transportation Integrated Search

2003-01-01

House Joint Resolution No. 23, 2002 Session of Virginia's General Assembly, requested that the Virginia Transportation Research Council and the Crash Investigation Team of Virginia Commonwealth University's Transportation Safety Training Center condu...

North Carolina "Sealed Corridor" phase IV assessment -- private crossings

DOT National Transportation Integrated Search

2012-07-31

The U.S. Department of Transportations (USDOT) Federal Railroad Administration tasked the USDOT Research and Innovative Technology Administrations John A. Volpe National Transportation Systems Center to document the success of the safety improv...

Locomotive crash energy management test plans

DOT National Transportation Integrated Search

2015-03-23

The Office of Research, Development, and Technology of the Federal Railroad Administration (FRA) and the Volpe Center are continuing to evaluate new technologies for increasing the safety of passengers and operators in rail equipment. The results of ...

Safety and Environment- Masterplan 2020 of DLR's Rocket Test Center Lampoldhausen

NASA Astrophysics Data System (ADS)

Haberzettl, Andreas; Dommers, Michael

2013-09-01

The German Aerospace Center DLR is the German research institute with approximately 7000 employees in 16 domestic locations. Among the research priorities of the German Aerospace Center DLR includes aerospace, energy and transport. DLR is institutionally supported by federal and state governments.Next funding sources arise in the context of third-party funds business (contract research and public contracts and subsidiaries). Main activities of the test center Lampoldshausen are testing of ARIANE's main and upper stage engines in the frame of ESA contracts.In the last years the test center of the DLR in Lampoldshausen has grown strongly, so that the number of employees is actually of about 230. The testing department is mainly responsible for rocket combustion testing according to customer requirements.Two kinds of test facilities are operated, sea level test benches and the altitude simulation test facilities.In addition to the DLR's growth also the activities of the industrial partner ASTRIUM has been elevated so that actually nearly 600 employees are present on site Lampoldshausen.The management of the site in relation to safety and security requires special measures with special respect to the presence of more people inside the testing area in order to guarantee trouble-free and safe experimental operation onsite the DLR's test plants. In order to meet with the future needs of continuing growth, the security and safety requirements have to be adopted.This report gives comprehensive outlook information about future possible scenarios of our coming tasks.Main driving force for future requests is the evolution of the rocket ARIANE. The testing of the new upper stage test facility for ARIANE 5 midlife evolution has been started. A new test position P5.2 is foreseen to perform the qualification of the new upper stage with the VINCI engine. This project will be very complex, in parallel running operation processes will require special procedures related to the overall safety of the test center.The site of Lampoldshausen with its test and supply facilities is subject to the restrictions of the German law BundesImissionsSchutzGesetz (derived from the European SEVESO-II directive) and its relevant ordinances, especially the Hazardous Incident Ordinance. Because of the complex framework effort which guarantees safety and security, Lampoldshausen has invested in people and processes in order to respect the restrictions of all relevant laws and ordinances as well as to guarantee the protection of people and the environment.Therefor a very special Master plan has been developed, with the goal to rearrange the complete testing area in order to be able to divide the area in certain sectors (testing range, technology and bureau) so that future testing enterprises will not affect almost free testing activities inside the site as it is in the present status.The paper provides comprehensive information related to the planned innovations including detailed background facts related to the foreseen safety and security standard applications.

Alternative Fuels Data Center: Natural Gas Safety after a Traffic Accident

Science.gov Websites

Natural Gas Safety after a Traffic Accident to someone by E-mail Share Alternative Fuels Data Center: Natural Gas Safety after a Traffic Accident on Facebook Tweet about Alternative Fuels Data Center : Natural Gas Safety after a Traffic Accident on Twitter Bookmark Alternative Fuels Data Center: Natural Gas

21 CFR 118.8 - Testing methodology for Salmonella Enteritidis (SE).

Code of Federal Regulations, 2010 CFR

2010-04-01

... Salmonella Web site is located at http://www.fda.gov/Food/ScienceResearch/LaboratoryMethods/ucm114716.htm... you may examine a copy at the Center for Food Safety and Applied Nutrition's Library, 5100 Paint... Edition, is located at http://www.fda.gov/Food/ScienceResearch/LaboratoryMethods/BacteriologicalAnalytical...

JDD, Inc. Database

NASA Technical Reports Server (NTRS)

Miller, David A., Jr.

2004-01-01

JDD Inc, is a maintenance and custodial contracting company whose mission is to provide their clients in the private and government sectors "quality construction, construction management and cleaning services in the most efficient and cost effective manners, (JDD, Inc. Mission Statement)." This company provides facilities support for Fort Riley in Fo,rt Riley, Kansas and the NASA John H. Glenn Research Center at Lewis Field here in Cleveland, Ohio. JDD, Inc. is owned and operated by James Vaughn, who started as painter at NASA Glenn and has been working here for the past seventeen years. This summer I worked under Devan Anderson, who is the safety manager for JDD Inc. in the Logistics and Technical Information Division at Glenn Research Center The LTID provides all transportation, secretarial, security needs and contract management of these various services for the center. As a safety manager, my mentor provides Occupational Health and Safety Occupation (OSHA) compliance to all JDD, Inc. employees and handles all other issues (Environmental Protection Agency issues, workers compensation, safety and health training) involving to job safety. My summer assignment was not as considered "groundbreaking research" like many other summer interns have done in the past, but it is just as important and beneficial to JDD, Inc. I initially created a database using a Microsoft Excel program to classify and categorize data pertaining to numerous safety training certification courses instructed by our safety manager during the course of the fiscal year. This early portion of the database consisted of only data (training field index, employees who were present at these training courses and who was absent) from the training certification courses. Once I completed this phase of the database, I decided to expand the database and add as many dimensions to it as possible. Throughout the last seven weeks, I have been compiling more data from day to day operations and been adding the information to the database. It now consists of seven different categories of data (carpet cleaning, forms, NASA Event Schedules, training certifications, wall and vent cleaning, work schedules, and miscellaneous) . I also did some field inspecting with the supervisors around the site and was present at all of the training certification courses that have been scheduled since June 2004. My future outlook for the JDD, Inc. database is to have all of company s information from future contract proposals, weekly inventory, to employee timesheets all in this same database.

Biomedical applications of tissue engineering technology: regulatory issues.

PubMed

Hellman, K B

1995-01-01

Novel emerging technologies such as tissue engineering, which utilize the approaches of molecular and cell biology, biotechnology, as well as materials science and engineering, are being used in the development of a wide range of biomedical products developed by industries regulated by the U.S. Food and Drug Administration (FDA). The FDA's mission is to promote and protect the public health by ensuring the safety and effectiveness of pharmaceuticals and medical devices, including those manufactured by novel technology, as assessed by scientific principles and methods. Regulatory review is conducted on a product-by-product basis. To accomplish its mission over the wide range of products in its regulatory purview, the FDA has six centers, each staffed with the scientific and regulatory expertise to evaluate the products in the center's jurisdiction. Recent legislative and regulatory changes are designed to simplify and facilitate the administrative process for evaluating novel combination products emanating from such interdisciplinary technology as tissue engineering and to resolve questions of product regulatory jurisdiction. Under the new procedures, the FDA may designate a lead FDA center for product review based on the primary mode of action of the combination product, with additional center(s) designated to assist in the evaluation in a collaborative or consultative capacity. In addition, FDA centers have increased their cooperation and information sharing with regard to evolving interdisciplinary technology. The FDA InterCenter Tissue Engineering Initiative was established to develop information on intercenter efforts in the evaluation of tissue engineering applications and to identify areas for further consideration. The FDA InterCenter Tissue Engineering Working Group, comprised of staff from the Center for Biologies Evaluation and Research (CBER), Center for Devices and Radiological Health (CDRH), Center for Drug Evaluation and Research (CDER), and Center for Veterinary Medicine (CVM) has developed a Draft Report considering recent developments in tissue engineering and scientific and regulatory issues in the product application areas. The Working Group has identified generic safety and effectiveness issues for consideration by the research and development community in its development of products. The FDA centers are using multiple approaches at their disposal in the evaluation of tissue engineered products including research, data and information monitoring, regulatory guidance, training and education, and cooperation with public and private groups.

Doppler Radar Profiler for Launch Winds at the Kennedy Space Center (Phase 1a)

NASA Technical Reports Server (NTRS)

Murri, Daniel G.

2011-01-01

The NASA Engineering and Safety Center (NESC) received a request from the, NASA Technical Fellow for Flight Mechanics at Langley Research Center (LaRC), to develop a database from multiple Doppler radar wind profiler (DRWP) sources and develop data processing algorithms to construct high temporal resolution DRWP wind profiles for day-of-launch (DOL) vehicle assessment. This document contains the outcome of Phase 1a of the assessment including Findings, Observations, NESC Recommendations, and Lessons Learned.

Preliminary Evaluation of an Aviation Safety Thesaurus' Utility for Enhancing Automated Processing of Incident Reports

NASA Technical Reports Server (NTRS)

Barrientos, Francesca; Castle, Joseph; McIntosh, Dawn; Srivastava, Ashok

2007-01-01

This document presents a preliminary evaluation the utility of the FAA Safety Analytics Thesaurus (SAT) utility in enhancing automated document processing applications under development at NASA Ames Research Center (ARC). Current development efforts at ARC are described, including overviews of the statistical machine learning techniques that have been investigated. An analysis of opportunities for applying thesaurus knowledge to improving algorithm performance is then presented.

UAB UT Annual Report : 2010-2011

DOT National Transportation Integrated Search

2011-01-01

The UAB UTC's theme, Traffic Safety and Injury Control was an excellent fit for the UAB Injury Control : Research Centers (ICRC) faculty, because it complemented the ICRCs Mission, which was: To help the : nation achieve a significant reduct...

Promising transit applications of fuel cells and alternative fuels

DOT National Transportation Integrated Search

2002-06-01

For over a decade, the Volpe Center has been providing technical support to the Federal Transit Administration (FTA) Office of Research, Demonstration and Innovation towards the development, deployment, field test and safety evaluation of advanced tr...

Track buckling prevention : theory, safety concepts, and applications

DOT National Transportation Integrated Search

2013-03-31

This report is a part of the John A. Volpe National Transportation Systems Centers Track Stability Research Program for the Federal Railroad Administration on thermal buckling of continuous welded rail (CWR) track and its prevention. Presented in ...

Hydrogen flammability limits and implications on fire safety of transportation vehicles

DOT National Transportation Integrated Search

2008-01-01

The recent establishment of the National University Transportation Center at MST under the "Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users," expands the research and education activities to include alternative tr...

Threat Assessment of Hazardous Materials Transportation in Aircraft Cargo Compartments.

DOT National Transportation Integrated Search

1999-12-01

The Volpe National Transportation Systems Center of the U.S. Department of Transportation's (DOT's) Research and Special Programs Administration (RSPA) has conducted a quantitative threat assessment for RSPA's Office of Hazardous Materials Safety (OH...

Sandia National Laboratories: National Security Missions: International

Science.gov Websites

Weapons Safety & Security Weapons Science & Technology Defense Systems & Assessments About Directed Research & Development Technology Deployment Centers Working With Sandia Working With Sandia Payable Contract Information Construction & Facilities Contract Audit Sandia's Economic Impact

Full-Scale Dynamic Testing of Locomotive Crashworthy Components.

DOT National Transportation Integrated Search

2015-10-01

The Office of Research, Development, and Technology of the Federal Railroad Administration (FRA) and the Volpe Center are evaluating new occupant protection technologies to increase the safety of passengers and operators in rail equipment. In view of...

Sandia National Laboratories: News

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Sandia National Laboratories: Locations

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Sandia National Laboratories: Careers

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Sandia National Laboratories: Mission

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Sandia National Laboratories:

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Sandia National Laboratories: Feedback

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

A study of NASA occupational injuries and property damage at Goddard Space Flight Center, Langley Research Center and Headquarters

NASA Technical Reports Server (NTRS)

1976-01-01

Analysis of NASA's accident/injury/illness and health data was performed. The analysis included: (1) an on-site study of the existing data; (2) evaluation of the findings to develop criteria for the subsequent implementation of safety and health standards; (3) preparation of a graphical loss control assessment; and (4) recommendations to reduce accident rates.

Enhancing the usability of CRT displays in test flight monitoring

NASA Astrophysics Data System (ADS)

Granaas, Michael M.; Sredinski, Victoria E.

1991-01-01

Enhancing the usability of Mission Control Center (MCC) CRT displays stands to improve the quality, productivity, and safety of flight-test research at the NASA Ames-Dryden Flight Research Facility. The results of this research suggests that much can be done to assist the user and improve the quality of flight research through the enhancement of current displays. This research has applications to a variety of flight data monitoring displays.

Propulsion Controls and Health Management Research at NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Garg, Sanjay

2002-01-01

With the increased emphasis on aircraft safety, enhanced performance and affordability, and the need to reduce the environmental impact of aircraft, there are many new challenges being faced by the designers of aircraft propulsion systems. The Controls and Dynamics Technology Branch at NASA Glenn Research Center (GRC) in Cleveland, Ohio, is leading and participating in various projects in partnership with the U.S. aerospace industry and academia to develop advanced controls and health management technologies that will help meet these challenges. These technologies are being developed with a view towards making the concept of "Intelligent Engines" a reality. The major research activities of the Controls and Dynamics Technology Branch are described in the following.

Propulsion Controls and Diagnostics Research at NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Garg, Sanjay

2007-01-01

With the increased emphasis on aircraft safety, enhanced performance and affordability, and the need to reduce the environmental impact of aircraft, there are many new challenges being faced by the designers of aircraft propulsion systems. Also the propulsion systems required to enable the National Aeronautics and Space Administration (NASA) Vision for Space Exploration in an affordable manner will need to have high reliability, safety and autonomous operation capability. The Controls and Dynamics Branch (CDB) at NASA Glenn Research Center (GRC) in Cleveland, Ohio, is leading and participating in various projects in partnership with other organizations within GRC and across NASA, the U.S. aerospace industry, and academia to develop advanced controls and health management technologies that will help meet these challenges through the concept of Intelligent Propulsion Systems. This paper describes the current activities of the CDB under the NASA Aeronautics Research and Exploration Systems Missions. The programmatic structure of the CDB activities is described along with a brief overview of each of the CDB tasks including research objectives, technical challenges, and recent accomplishments. These tasks include active control of propulsion system components, intelligent propulsion diagnostics and control for reliable fault identification and accommodation, distributed engine control, and investigations into unsteady propulsion systems.

Evolution of International Space Station Program Safety Review Processes and Tools

NASA Technical Reports Server (NTRS)

Ratterman, Christian D.; Green, Collin; Guibert, Matt R.; McCracken, Kristle I.; Sang, Anthony C.; Sharpe, Matthew D.; Tollinger, Irene V.

2013-01-01

The International Space Station Program at NASA is constantly seeking to improve the processes and systems that support safe space operations. To that end, the ISS Program decided to upgrade their Safety and Hazard data systems with 3 goals: make safety and hazard data more accessible; better support the interconnection of different types of safety data; and increase the efficiency (and compliance) of safety-related processes. These goals are accomplished by moving data into a web-based structured data system that includes strong process support and supports integration with other information systems. Along with the data systems, ISS is evolving its submission requirements and safety process requirements to support the improved model. In contrast to existing operations (where paper processes and electronic file repositories are used for safety data management) the web-based solution provides the program with dramatically faster access to records, the ability to search for and reference specific data within records, reduced workload for hazard updates and approval, and process support including digital signatures and controlled record workflow. In addition, integration with other key data systems provides assistance with assessments of flight readiness, more efficient review and approval of operational controls and better tracking of international safety certifications. This approach will also provide new opportunities to streamline the sharing of data with ISS international partners while maintaining compliance with applicable laws and respecting restrictions on proprietary data. One goal of this paper is to outline the approach taken by the ISS Progrm to determine requirements for the new system and to devise a practical and efficient implementation strategy. From conception through implementation, ISS and NASA partners utilized a user-centered software development approach focused on user research and iterative design methods. The user-centered approach used on the new ISS hazard system utilized focused user research and iterative design methods employed by the Human Computer Interaction Group at NASA Ames Research Center. Particularly, the approach emphasized the reduction of workload associated with document and data management activities so more resources can be allocated to the operational use of data in problem solving, safety analysis, and recurrence control. The methods and techniques used to understand existing processes and systems, to recognize opportunities for improvement, and to design and review improvements are described with the intent that similar techniques can be employed elsewhere in safety operations. A second goal of this paper is to provide and overview of the web-based data system implemented by ISS. The software selected for the ISS hazard systemMission Assurance System (MAS)is a NASA-customized vairant of the open source software project Bugzilla. The origin and history of MAS as a NASA software project and the rationale for (and advantages of) using open-source software are documented elsewhere (Green, et al., 2009).

Airport Simulations Using Distributed Computational Resources

NASA Technical Reports Server (NTRS)

McDermott, William J.; Maluf, David A.; Gawdiak, Yuri; Tran, Peter; Clancy, Daniel (Technical Monitor)

2002-01-01

The Virtual National Airspace Simulation (VNAS) will improve the safety of Air Transportation. In 2001, using simulation and information management software running over a distributed network of super-computers, researchers at NASA Ames, Glenn, and Langley Research Centers developed a working prototype of a virtual airspace. This VNAS prototype modeled daily operations of the Atlanta airport by integrating measured operational data and simulation data on up to 2,000 flights a day. The concepts and architecture developed by NASA for this prototype are integral to the National Airspace Simulation to support the development of strategies improving aviation safety, identifying precursors to component failure.

What we know and don't know about the bioeffects of nanoparticles: developing experimental approaches for safety assessment.

PubMed

Stratmeyer, Mel E; Goering, Peter L; Hitchins, Victoria M; Umbreit, Thomas H

2010-08-01

The Center for Devices and Radiological Health (CDRH) of the US Food and Drug Administration (FDA) regulates nano-based medical products and therefore is required to address the safety and biological effects of nano-scale materials used in these products. Both in vitro and in vivo toxicological research studies are being conducted at the FDA to help determine the risks versus benefits of these new products. This article will briefly summarize some of the initial research findings from FDA-CDRH studies using TiO(2), polystyrene, and silicon nanoparticles.

Research and development program plan for the Center for Engineering Systems Advanced Research (CESAR)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weisbin, C.R.; Hamel, W.R.; Barhen, J.

1986-02-01

The Oak Ridge National Laboratory has established the Center for Engineering Systems Advanced Research (CESAR) for the purpose of addressing fundamental problems of intelligent machine technologies. The purpose of this document is to establish a framework and guidelines for research and development within ORNL's CESAR program in areas pertaining to intelligent machines. The specific objective is to present a CESAR Research and Development Plan for such work with a planning horizon of five to ten years, i.e., FY 1985 to FY 1990 and beyond. As much as possible, the plan is based on anticipated DOE needs in the area ofmore » productivity increase and safety to the end of this century.« less

Vehicle-to-vehicle communications in mixed passenger-freight convoys : [research brief].

DOT National Transportation Integrated Search

2016-09-01

Freight traffic in California depends, to a large degree, on trucks, due to their flexibility in : visiting warehouses, distribution centers, and terminals. However, trucks pose major challenges : to traffic and road safety. Accidents involving truck...

The development of a rail passenger coach car crush zone

DOT National Transportation Integrated Search

2002-03-21

There is currently an active program within the United States to improve the passive safety of train systems. In particular, the Volpe Center is supporting the Federal Railroad Administrations research that includes numerous analytical studies and...

Cambridge Safer Truck Initiative : Vehicle-Based Strategies to Protect Pedestrians and Bicyclists

DOT National Transportation Integrated Search

2016-03-01

This report summarizes Volpe, The National Transportation Systems Centers (Volpes) research and recommendations for the City of Cambridge for implementing a number of proven vehicle safety strategies, including truck side guards, blind spot mir...

Preliminary finite element analysis of locomotive crashworthy components

DOT National Transportation Integrated Search

2011-09-21

The Office of Research and Development of the Federal Railroad Administration (FRA) and the Volpe Center are continuing to evaluate new technologies for increasing the safety of passengers and operators in rail equipment. In recognition of the import...

A Preliminary Review of English Proficiency and Safe Commercial Motor Vehicle Operation.

DOT National Transportation Integrated Search

2008-07-01

Under sponsorship from the U.S. Department of Transportation Federal Motor Carrier Safety Administration, Office of Bus and Truck Standards and Operations, the John A. Volpe National Transportation Systems Center performed a preliminary research stud...

Sandia National Laboratories: Search Results

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Sandia National Laboratories: Social Media

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Sandia National Laboratories: News: Videos

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Sandia National Laboratories: About Sandia

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Sandia National Laboratories: News: Image Gallery

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Sandia National Laboratories: Privacy and Security

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Sandia National Laboratories: Sandia Digital Media

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Sandia National Laboratories: Careers: Special Programs

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Sandia National Laboratories: Integrated Military Systems

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Sandia National Laboratories: News: Image Gallery

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Environmental Management System Pollution Prevention History 60 impacts Diversity Locations Facts & Figures Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers

Food safety intervention research at the Eastern Regional Research Center: innovative sanitizers, natural antimicrobials and nonthermal processing technologies

USDA-ARS?s Scientific Manuscript database

Foodborne pathogens such as Salmonella, Listeria monocytogenes and Escherichia coli O157:H7cause millions of illnesses every year. A variety of technologies have been advanced in recent years to expand on the suite of tools available to food processors. At the US Department of Agriculture’s Eastern ...

Demystifying the U.S. Food and Drug Administration: I. Understanding agency structure and function.

PubMed

Levi, Benjamin; Lisiecki, Jeffrey; Rubin, Peter; D'Amico, Richard A; Hume, Keith M; Seward, Bill; Cederna, Paul S

2014-06-01

The U.S. Food and Drug Administration is the government agency responsible for oversight of the safety and efficacy of pharmaceuticals and devices, including biologics and devices that combine biologics with other materials. Within the U.S. Food and Drug Administration, the Center for Biologics Evaluation and Research is specifically responsible for the evaluation and approval of biological products. This department of the U.S. Food and Drug Administration has a series of mechanisms in place to aid researchers in the process of developing new biologics. This article outlines the study phases involved in developing new biologics and how the Center for Biologics Evaluation and Research and investigators can work together to facilitate this process. It also discusses issues specific to biologics that have been encountered in the past and that investigators should consider when developing and obtaining approval for new biologics. The equivalent center within the U.S. Food and Drug Administration for approving medical devices is the Center for Devices and Radiological Health. The equivalent process of development and approval of medical devices is similarly discussed. Finally, essential contacts for investigators within the Center for Biologics Evaluation and Research and the Center for Devices and Radiological Health are provided.

The use of high-fidelity human patient simulation as an evaluative tool in the development of clinical research protocols and procedures.

PubMed

Wright, Melanie C; Taekman, Jeffrey M; Barber, Linda; Hobbs, Gene; Newman, Mark F; Stafford-Smith, Mark

2005-12-01

Errors in clinical research can be costly, in terms of patient safety, data integrity, and data collection. Data inaccuracy in early subjects of a clinical study may be associated with problems in the design of the protocol, procedures, and data collection tools. High-fidelity patient simulation centers provide an ideal environment to apply human-centered design to clinical trial development. A draft of a complex clinical protocol was designed, evaluated and modified using a high-fidelity human patient simulator in the Duke University Human Simulation and Patient Safety Center. The process included walk-throughs, detailed modifications of the protocol and development of procedural aids. Training of monitors and coordinators provided an opportunity for observation of performance that was used to identify further improvements to the protocol. Evaluative steps were used to design the research protocol and procedures. Iterative modifications were made to the protocol and data collection tools. The success in use of human simulation in the preparation of a complex clinical drug trial suggests the benefits of human patient simulation extend beyond training and medical equipment evaluation. Human patient simulation can provide a context for informal expert evaluation of clinical protocol design and for formal "rehearsal" to evaluate the efficacy of procedures and support tools.

Science and technology issues in spacecraft fire safety

NASA Technical Reports Server (NTRS)

Friedman, Robert; Sacksteder, Kurt R.

1987-01-01

The space station, a permanently-inhabited orbiting laboratory, places new demands on spacecraft fire safety. Long-duration missions may call for more-constrained fire controls, but the accessibility of the space station to a variety of users may call for less-restrictive measures. This paper discusses fire safety issues through a review of the state of the art and a presentation of key findings from a recent NASA Lewis Research Center Workshop. The subjects covered are the fundamental science of low-gravity combustion and the technology advances in fire detection, extinguishment, materials assessment, and atmosphere selection. Key concerns are for the adoption of a fire-safe atmosphere and the substitution for the effective but toxic extinguishant, halon 1301. The fire safety studies and reviews provide several recommendations for further action. One is the expanded research in combustion, sensors, and materials in the low-gravity environment of space. Another is the development of generalized fire-safety standards for spacecraft through cooperative endeavors with aerospace and outside Government and industry sources.

M-CASTL 2008 synthesis report : volume 1, older adult mobility.

DOT National Transportation Integrated Search

2008-04-01

The theme of the Michigan Center for Advancing Safe Transportation throughout the Lifespan (M-CASTL) is Safety : and Mobility throughout the Lifespan. The purpose of the annual synthesis report is to identify short and long-term : research needs that...

Finite element analysis and full-scale testing of locomotive crashworthy components

DOT National Transportation Integrated Search

2013-04-15

The Office of Research and Development of the Federal Railroad Administration (FRA) and the Volpe Center are continuing to evaluate new technologies for increasing the safety of passengers and operators in rail equipment. In recognition of the import...

5. VIEW NORTH OF TEST SECTION IN FULLSCALE WIND TUNNEL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. VIEW NORTH OF TEST SECTION IN FULL-SCALE WIND TUNNEL WITH FREE-FLIGHT MODEL OF A BOEING 737 SUSPENDED FROM A SAFETY CABLE. - NASA Langley Research Center, Full-Scale Wind Tunnel, 224 Hunting Avenue, Hampton, Hampton, VA

Sandia National Laboratories: News: Publications: Environmental Reports

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Sandia National Laboratories: Sandia National Laboratories: News: Events

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Sandia National Laboratories: About Sandia: Environmental Responsibility

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Sandia National Laboratories: About Sandia: Community Involvement

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Sandia National Laboratories: News: Publications: HPC Reports

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Sandia National Laboratories: Community Involvement: Volunteer Programs

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Sandia National Laboratories: National Security Missions: International

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Weapons Safety & Security Weapons Science & Technology Defense Systems & Assessments About Directed Research & Development Technology Deployment Centers Working With Sandia Working With Sandia Licensing & Technology Transfer Browse Technology Portfolios Technology Partnerships Business, Industry

Sandia National Laboratories: News: Search Sandia Publications

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Sandia National Laboratories: Working with Sandia: Small Business

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Sandia National Laboratories: News: Publications: Strategic Plan

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Sandia National Laboratories: News: Media Resources: Media Contacts

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Sandia National Laboratories: Sandia Enabled Communications and

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Sandia National Laboratories: Employee & Retiree Resources: Technical

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Sandia National Laboratories: Z Pulsed Power Facility

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Sandia National Laboratories: Advanced Simulation and Computing

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Sandia National Laboratories: News: Publications: Annual Report

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Sandia National Laboratories: Employee & Retiree Resources: Remote Access

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Sandia National Laboratories: National Security Missions: International

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Prevention History 60 impacts Diversity Locations Facts & Figures Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Defense Systems & Assessments About Directed Research & Development Technology Deployment Centers Working With Sandia Working With Sandia

Advanced research workshop: nuclear materials safety

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jardine, L J; Moshkov, M M

The Advanced Research Workshop (ARW) on Nuclear Materials Safety held June 8-10, 1998, in St. Petersburg, Russia, was attended by 27 Russian experts from 14 different Russian organizations, seven European experts from six different organizations, and 14 U.S. experts from seven different organizations. The ARW was conducted at the State Education Center (SEC), a former Minatom nuclear training center in St. Petersburg. Thirty-three technical presentations were made using simultaneous translations. These presentations are reprinted in this volume as a formal ARW Proceedings in the NATO Science Series. The representative technical papers contained here cover nuclear material safety topics on themore » storage and disposition of excess plutonium and high enriched uranium (HEU) fissile materials, including vitrification, mixed oxide (MOX) fuel fabrication, plutonium ceramics, reprocessing, geologic disposal, transportation, and Russian regulatory processes. This ARW completed discussions by experts of the nuclear materials safety topics that were not covered in the previous, companion ARW on Nuclear Materials Safety held in Amarillo, Texas, in March 1997. These two workshops, when viewed together as a set, have addressed most nuclear material aspects of the storage and disposition operations required for excess HEU and plutonium. As a result, specific experts in nuclear materials safety have been identified, know each other from their participation in t he two ARW interactions, and have developed a partial consensus and dialogue on the most urgent nuclear materials safety topics to be addressed in a formal bilateral program on t he subject. A strong basis now exists for maintaining and developing a continuing dialogue between Russian, European, and U.S. experts in nuclear materials safety that will improve the safety of future nuclear materials operations in all the countries involved because of t he positive synergistic effects of focusing these diverse backgrounds of nuclear experience on a common objectiveÑthe safe and secure storage and disposition of excess fissile nuclear materials.« less

77 FR 75016 - Safety Zone: Gilmerton Bridge Center Span Float-in, Elizabeth River; Norfolk, Portsmouth, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-19

...-AA00 Safety Zone: Gilmerton Bridge Center Span Float-in, Elizabeth River; Norfolk, Portsmouth, and... final rule establishing a safety zone around the Gilmerton Bridge center span barge. Inadvertently, this... Gilmerton Bridge center span barge (77 FR 73541). Inadvertently, this rule included an error in the...

77 FR 44544 - Safety Zone; Gilmerton Bridge Center Span Float-In, Elizabeth River; Norfolk, Portsmouth, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

...-AA00 Safety Zone; Gilmerton Bridge Center Span Float-In, Elizabeth River; Norfolk, Portsmouth, and... withdrawing its proposed rule concerning the Gilmerton Bridge Center Span Float-in and bridge construction of... ``Safety Zone; Gilmerton Bridge Center Span Float-in, Elizabeth River; Norfolk, Portsmouth, and Chesapeake...

General aviation crash safety program at Langley Research Center

NASA Technical Reports Server (NTRS)

Thomson, R. G.

1976-01-01

The purpose of the crash safety program is to support development of the technology to define and demonstrate new structural concepts for improved crash safety and occupant survivability in general aviation aircraft. The program involves three basic areas of research: full-scale crash simulation testing, nonlinear structural analyses necessary to predict failure modes and collapse mechanisms of the vehicle, and evaluation of energy absorption concepts for specific component design. Both analytical and experimental methods are being used to develop expertise in these areas. Analyses include both simplified procedures for estimating energy absorption capabilities and more complex computer programs for analysis of general airframe response. Full-scale tests of typical structures as well as tests on structural components are being used to verify the analyses and to demonstrate improved design concepts.

The Public Health Impact of Herbs and Nutritional Supplements.

PubMed

Cassileth, Barrie R; Heitzer, Marjet; Wesa, Kathleen

2009-08-01

Dietary supplement use has increased exponentially in recent years despite the lack of regulatory oversight and in the face of growing safety concerns. This paper provides an overview of the public health implications and safety concerns associated with dietary supplement use, especially by cancer patients. Botanical research is actively pursued at the Memorial Sloan-Kettering Cancer Center (MSKCC) Integrative Medicine department. Work of the MSKCC Center for the Study of Botanical Immunomodulators is described, and guidelines for cancer patients' use of dietary supplements outlined. Herbs and other botanicals are complex, physiologically active agents, but little is known about most of the popular, widely available dietary supplements. Herb-drug interactions, a major concern, are exacerbated in the cancer setting. Biologically active agents may interfere with chemotherapy and other prescription medications. They may exert anti-coagulant activity at rather inconvenient times such as during surgery, and create other serious problems. Research on the bioavailability, effective dosage, safety and benefits of these complex agents is sorely needed. Oncology professionals and other healthcare providers should educate themselves and their patients about these issues. Probably the largest, continuously-updated free information resource is MSKCC's AboutHerbs website (www.mskcc.org/AboutHerbs).

The Kaiser Permanente implant registries: effect on patient safety, quality improvement, cost effectiveness, and research opportunities.

PubMed

Paxton, Elizabeth W; Inacio, Maria Cs; Kiley, Mary-Lou

2012-01-01

Considering the high cost, volume, and patient safety issues associated with medical devices, monitoring of medical device performance is critical to ensure patient safety and quality of care. The purpose of this article is to describe the Kaiser Permanente (KP) implant registries and to highlight the benefits of these implant registries on patient safety, quality, cost effectiveness, and research. Eight KP implant registries leverage the integrated health care system's administrative databases and electronic health records system. Registry data collected undergo quality control and validation as well as statistical analysis. Patient safety has been enhanced through identification of affected patients during major recalls, identification of risk factors associated with outcomes of interest, development of risk calculators, and surveillance programs for infections and adverse events. Effective quality improvement activities included medical center- and surgeon-specific profiles for use in benchmarking reports, and changes in practice related to registry information output. Among the cost-effectiveness strategies employed were collaborations with sourcing and contracting groups, and assistance in adherence to formulary device guidelines. Research studies using registry data included postoperative complications, resource utilization, infection risk factors, thromboembolic prophylaxis, effects of surgical delay on concurrent injuries, and sports injury patterns. The unique KP implant registries provide important information and affect several areas of our organization, including patient safety, quality improvement, cost-effectiveness, and research.

Informatics for patient safety: a nursing research perspective.

PubMed

Bakken, Suzanne

2006-01-01

In Crossing the Quality Chasm, the Institute of Medicine (IOM) Committee on Quality of Health Care in America identified the critical role of information technology in designing a health system that produces care that is "safe, effective, patient-centered, timely, efficient, and equitable" (Committee on Quality of Health Care in America, 2001, p. 164). A subsequent IOM report contends that improved information systems are essential to a new health care delivery system that "both prevents errors and learns from them when they occur" (Committee on Data Standards for Patient Safety, 2004, p. 1). This review specifically highlights the role of informatics processes and information technology in promoting patient safety and summarizes relevant nursing research. First, the components of an informatics infrastructure for patient safety are described within the context of the national framework for delivering consumer-centric and information-rich health care and using the National Health Information Infrastructure (NHII) (Thompson & Brailer, 2004). Second, relevant nursing research is summarized; this includes research studies that contributed to the development of selected infrastructure components as well as studies specifically focused on patient safety. Third, knowledge gaps and opportunities for nursing research are identified for each main topic. The health information technologies deployed as part of the national framework must support nursing practice in a manner that enables prevention of medical errors and promotion of patient safety and contributes to the development of practice-based nursing knowledge as well as best practices for patient safety. The seminal work that has been completed to date is necessary, but not sufficient, to achieve this objective.

Alternative Fuels Data Center: Maintenance and Safety of Hybrid and Plug-In

Science.gov Websites

Electric Vehicles Maintenance and Safety of Hybrid and Plug-In Electric Vehicles to someone by E-mail Share Alternative Fuels Data Center: Maintenance and Safety of Hybrid and Plug-In Electric Vehicles on Facebook Tweet about Alternative Fuels Data Center: Maintenance and Safety of Hybrid and Plug

Implementation of the Enhanced Flight Termination System at National Aeronautics and Space Administration Dryden Flight Research Center

NASA Technical Reports Server (NTRS)

Tow, David

2010-01-01

This paper discusses the methodology, requirements, tests, and results of the implementation of the current operating capability for the Enhanced Flight Termination System (EFTS) at the National Aeronautics and Space Administration (NASA) Dryden Flight Research Center (DFRC). The implementation involves the development of the EFTS at NASA DFRC starting from the requirements to system safety review to full end to end system testing, and concluding with the acceptance of the system as an operational system. The paper discusses the first operational usage and subsequent flight utilizing EFTS successfully.

Chemical research projects office: An overview and bibliography, 1975-1980

NASA Technical Reports Server (NTRS)

Kourtides, D. A.; Heimbuch, A. H.; Parker, J. A.

1980-01-01

The activities of the Chemical Research Projects Office at Ames Research Center, Moffett Field, California are reported. The office conducts basic and applied research in the fields of polymer chemistry, computational chemistry, polymer physics, and physical and organic chemistry. It works to identify the chemical research and technology required for solutions to problems of national urgency, synchronous with the aeronautic and space effort. It conducts interdisciplinary research on chemical problems, mainly in areas of macromolecular science and fire research. The office also acts as liaison with the engineering community and assures that relevant technology is made available to other NASA centers, agencies, and industry. Recent accomplishments are listed in this report. Activities of the three research groups, Polymer Research, Aircraft Operating and Safety, and Engineering Testing, are summarized. A complete bibliography which lists all Chemical Research Projects Office publications, contracts, grants, patents, and presentations from 1975 to 1980 is included.

Assessment of Ocean Wave Model used to Analyze the Constellation Program (CxP) Orion Project Crew Module Water Landing Conditions

NASA Technical Reports Server (NTRS)

Smith, Bryan K.; Bouchard, Richard; Teng, Chung-Chu; Dyson, Rodger; Jenson, Robert; OReilly, William; Rogers, Erick; Wang, David; Volovoi, Vitali

2009-01-01

Mr. Christopher Johnson, NASA's Systems Manager for the Orion Project Crew Module (CM) Landing and Recovery at the Johnson Space Center (JSC), and Mr. James Corliss, Project Engineer for the Orion CM Landing System Advanced Development Project at the Langley Research Center (LaRC) requested an independent assessment of the wave model that was developed to analyze the CM water landing conditions. A NASA Engineering and Safety Center (NESC) initial evaluation was approved November 20, 2008. Mr. Bryan Smith, NESC Chief Engineer at the NASA Glenn Research Center (GRC), was selected to lead this assessment. The Assessment Plan was presented and approved by the NESC Review Board (NRB) on December 18, 2008. The Assessment Report was presented to the NRB on March 12, 2009. This document is the final Assessment Report.

Defining Safety in the Nursing Home Setting: Implications for Future Research.

PubMed

Simmons, Sandra F; Schnelle, John F; Sathe, Nila A; Slagle, Jason M; Stevenson, David G; Carlo, Maria E; McPheeters, Melissa L

2016-06-01

Currently, the Agency for Healthcare Research and Quality (AHRQ) Common Format for nursing homes (NHs) accommodates voluntary reporting for 4 adverse events: falls with injury, pressure ulcers, medication errors, and infections. In 2015, AHRQ funded a technical brief to describe the state of the science related to safety in the NH setting to inform a research agenda. Thirty-six recent systematic reviews evaluated NH safety-related interventions to address these 4 adverse events and reported mostly mixed evidence about effective approaches to ameliorate them. Furthermore, these 4 events are likely inadequate to capture safety issues that are unique to the NH setting and encompass other domains related to residents' quality of care and quality of life. Future research needs include expanding our definition of safety in the NH setting, which differs considerably from that of hospitals, to include contributing factors to adverse events as well as more resident-centered care measures. Second, future research should reflect more rigorous implementation science to include objective measures of care processes related to adverse events, intervention fidelity, and staffing resources for intervention implementation to inform broader uptake of efficacious interventions. Weaknesses in implementation contribute to the current inconclusive and mixed evidence base as well as remaining questions about what outcomes are even achievable in the NH setting, given the complexity of most resident populations. Also related to implementation, future research should determine the effects of specific staffing models on care processes related to safety outcomes. Last, future efforts should explore the potential for safety issues in other care settings for older adults, most notably dementia care within assisted living. Copyright © 2016 AMDA – The Society for Post-Acute and Long-Term Care Medicine. All rights reserved.

Norms Versus Security: What is More Important to Japan’s View of Nuclear Weapons

DTIC Science & Technology

2017-03-01

objectives: “1) prevent the spread of nuclear weapons and weapons technology, 2) promote cooperation in the peaceful uses of nuclear energy , and 3...http://www.world- nuclear.org/information-library/safety-and-security/safety-of-plants/fukushima-accident.aspx. 40 “Japanese Wary of Nuclear Energy ...PewResearchCenter, accessed February 22, 2017. http://www.pewglobal.org/2012/06/05/japanese-wary-of- nuclear - energy / 41 Malcolm Foster, “Thousands

Bibliography of reports on research sponsored by the NRC Office of Nuclear Regulatory Research, July--December 1976

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buchanan, J.R.

A bibliography of 148 reports published by contractors of the NRC Office of Nuclear Regulatory Research during the period July through December 1976 is presented along with abstracts from the Nuclear Safety Information Center computer file. The bibliography has been sorted into the subject categories used by NRC to organize the research program. Within the subject categories, the reports are sorted by contractor organization and then chronologically. A brief description of the NRC research program precedes the bibliography.

78 FR 23158 - Organization and Delegation of Duties

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-18

... management actions of major significance, such as those relating to changes in basic organization pattern... regard to rulemaking, enforcement, vehicle safety research and statistics and data analysis, provides... Administrator for the National Center for Statistics and Analysis, and the Associate Administrator for Vehicle...

Sandia National Laboratories: What Sandia Looks For In Our Suppliers

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Sandia National Laboratories: Working with Sandia: What Does Sandia Buy?

Science.gov Websites

Programs Nuclear Weapons About Nuclear Weapons Safety & Security Weapons Science & Technology Robotics R&D 100 Awards Laboratory Directed Research & Development Technology Deployment Centers Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios

Closing the information gap: informing better medical decisionmaking through the use of post-market safety and comparative effectiveness information.

PubMed

Fox, Bethany

2012-01-01

While FDA gathers vast amounts of data about prescription drugs prior to their marketing approval, important information about the relative effectiveness and long term safety of products is not required for approval, and often is never collected. Increased postmarket research on the safety and comparative effectiveness of products would improve medical decisionmaking and lead to better clinical outcomes. Fortunately, Congress has recognized the value of this information for healthcare professionals. In response to a congressional mandate in the FDA Amendments Act (FDAAA), FDA is developing the Sentinel Initiative, an active surveillance system for monitoring postmarket drug safety issues. FDAAA also authorized FDA to require a drug sponsor to conduct postmarket safety studies or clinical trials to address a specific safety concern. To increase the repository of comparative effectiveness information, Congress established the Patient-Centered Outcomes Research Institute (PCORI) in the Patient Protection and Affordable Care Act (PPACA), directing it to manage comparative effectiveness research (CER). This article discusses the need for better safety and comparative effectiveness information and outlines methods to efficiently conduct the research and communicate it effectively to healthcare professionals. Coordination between FDA and the PCORI in gathering and communicating postmarket information is recommended. Medical source data collected by the Sentinel Initiative should be used for CER in addition to postmarket safety surveillance, and FDA and the PCORI should adopt identical standards for the distribution and communication of CER. Coordination between the two entities is recommended to save costs, reduce duplication of efforts, and to generate and communicate more information on prescription drugs for medical decisionmakers.

Advanced and recurring thymic carcinoma is target of new clinical trial | Center for Cancer Research

Cancer.gov

Adults diagnosed with thymic carcinoma who overexpress the protein mesothelin may be eligible to participate in a new clinical trial at the NIH Clinical Center. The study will look at the safety and effectiveness of an investigational drug, anetumab ravtansine, developed by Bayer HealthCare Pharmaceuticals. The drug works by binding to mesothelin, therefore overexpression of the protein could be useful for targeting cancer cells. Read more...

Report of the Defense Science Board Task Force on Department of Defense Biological Safety and Security Program

DTIC Science & Technology

2009-05-01

Three (NAMRU-3) - Lima, Peru : Naval Medical Research Center Detachment (NMRCD) *These labs are co-located. To provide some measure of the scope and...Aceh, Indonesia and the more recent earthquakes in central Java and Peru . Edgewood Chemical Biological Center (ECBC) ECBC’s science and technology... diabetes , obesity, cancer, psychiatric disorders, problems of pregnancy, AIDS, hepatitis, malaria, parasitic infections, and a host of other

Glenn Extreme Environments Rig (GEER) Independent Review

NASA Technical Reports Server (NTRS)

Jankovsky, Robert S.; Smiles, Michael D.; George, Mark A.; Ton, Mimi C.; Le, Son K.

2015-01-01

The Chief of the Space Science Project Office at Glenn Research Center (GRC) requested support from the NASA Engineering and Safety Center (NESC) to satisfy a request from the Science Mission Directorate (SMD) Associate Administrator and the Planetary Science Division Chief to obtain an independent review of the Glenn Extreme Environments Rig (GEER) and the operational controls in place for mitigating any hazard associated with its operation. This document contains the outcome of the NESC assessment.

Bandwidth Enabled Flight Operations: Examining the Possibilities

NASA Technical Reports Server (NTRS)

Pisanich, Greg; Renema, Fritz; Clancy, Dan (Technical Monitor)

2002-01-01

The Bandwidth Enabled Flight Operations project is a research effort at the NASA Ames Research Center to investigate the use of satellite communications to improve aviation safety and capacity. This project is a follow on to the AeroSAPIENT Project, which demonstrated methods for transmitting high bandwidth data in various configurations. For this research, we set a goal to nominally use only 10 percent of the available bandwidth demonstrated by AeroSAPIENT or projected by near-term technology advances. This paper describes the results of our research, including available satellite bandwidth, commercial and research efforts to provide these services, and some of the limiting factors inherent with this communications medium. It also describes our investigation into the needs of the stakeholders (Airlines, Pilots, Cabin Crews, ATC, Maintenance, etc). The paper also describes our development of low-cost networked flight deck and airline operations center simulations that were used to demonstrate two application areas: Providing real time weather information to the commercial flight deck, and enhanced crew monitoring and control for airline operations centers.

Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) Project KDP-C Review

NASA Technical Reports Server (NTRS)

Grindle, Laurie; Sakahara, Robert; Hackenberg, Davis; Johnson, William

2017-01-01

The topics discussed are the UAS-NAS project life-cycle and ARMD thrust flow down, as well as the UAS environments and how we operate in those environments. NASA's Armstrong Flight Research Center at Edwards, CA, is leading a project designed to help integrate unmanned air vehicles into the world around us. The Unmanned Aircraft Systems Integration in the National Airspace System project, or UAS in the NAS, will contribute capabilities designed to reduce technical barriers related to safety and operational challenges associated with enabling routine UAS access to the NAS. The project falls under the Integrated Systems Research Program office managed at NASA Headquarters by the agency's Aeronautics Research Mission Directorate. NASA's four aeronautics research centers - Armstrong, Ames Research Center, Langley Research Center, and Glenn Research Center - are part of the technology development project. With the use and diversity of unmanned aircraft growing rapidly, new uses for these vehicles are constantly being considered. Unmanned aircraft promise new ways of increasing efficiency, reducing costs, enhancing safety and saving lives 460265main_ED10-0132-16_full.jpg Unmanned aircraft systems such as NASA's Global Hawks (above) and Predator B named Ikhana (below), along with numerous other unmanned aircraft systems large and small, are the prime focus of the UAS in the NAS effort to integrate them into the national airspace. Credits: NASA Photos 710580main_ED07-0243-37_full.jpg The UAS in the NAS project envisions performance-based routine access to all segments of the national airspace for all unmanned aircraft system classes, once all safety-related and technical barriers are overcome. The project will provide critical data to such key stakeholders and customers as the Federal Aviation Administration and RTCA Special Committee 203 (formerly the Radio Technical Commission for Aeronautics) by conducting integrated, relevant system-level tests to adequately address safety and operational challenges of national airspace access by unmanned aircraft systems, or UAS. In the process, the project will work with other key stakeholders to define necessary deliverables and products to help enable such access. Within the project, NASA is focusing on five sub-projects. These five focus areas include assurance of safe separation of unmanned aircraft from manned aircraft when flying in the national airspace; safety-critical command and control systems and radio frequencies to enable safe operation of UAS; human factors issues for ground control stations; airworthiness certification standards for UAS avionics and integrated tests and evaluation designed to determine the viability of emerging UAS technology. Five Focus Areas of the UAS Integration in the NAS Project Separation Assurance Provide an assessment of how planned Next Generation Air Transportation System (NextGen) separation assurance systems, with different functional allocations, perform for UAS in mixed operations with manned aircraft Assess the applicability to UAS and the performance of NASA NextGen separation assurance systems in flight tests with realistic latencies and uncertain trajectories Assess functional allocations ranging from today's ground-based, controller-provided aircraft separation to fully autonomous airborne self-separation Communications Develop data and rationale to obtain appropriate frequency spectrum allocations to enable safe and efficient operation of UAS in the NAS Develop and validate candidate secure safety-critical command and control system/subsystem test equipment for UAS that complies with UAS international/national frequency regulations, standards and recommended practices and minimum operational and aviation system performance standards for UAS Perform analysis to support recommendations for integration of safety-critical command and control systems and air traffic control communications to ensure safe and efficient operation of UAS in the NAS Human Systems Integration Develop a research test bed and database to provide data and proof of concept for GCS - ground control station - operations in the NAS Coordinate with standards organizations to develop human-factors guidelines for GCS operation in the NAS Certification Define a UAS classification scheme and approach to determining Federal Aviation Regulation airworthiness requirements applicable to all UAS digital avionics Provide hazard and risk-related data to support development of type design criteria and best development practices Integrated Tests and Evaluation Integrate and test mature concepts from technical elements to demonstrate and test viability Evaluate the performance of technology development in a relevant environment (full-mission, human-in-the-loop simulations and flight tests)

Patient safety goals for the proposed Federal Health Information Technology Safety Center.

PubMed

Sittig, Dean F; Classen, David C; Singh, Hardeep

2015-03-01

The Office of the National Coordinator for Health Information Technology is expected to oversee creation of a Health Information Technology (HIT) Safety Center. While its functions are still being defined, the center is envisioned as a public-private entity focusing on promotion of HIT related patient safety. We propose that the HIT Safety Center leverages its unique position to work with key administrative and policy stakeholders, healthcare organizations (HCOs), and HIT vendors to achieve four goals: (1) facilitate creation of a nationwide 'post-marketing' surveillance system to monitor HIT related safety events; (2) develop methods and governance structures to support investigation of major HIT related safety events; (3) create the infrastructure and methods needed to carry out random assessments of HIT related safety in complex HCOs; and (4) advocate for HIT safety with government and private entities. The convening ability of a federally supported HIT Safety Center could be critically important to our transformation to a safe and effective HIT enabled healthcare system. © The Author 2014. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Electrical Characterizations of Lightning Strike Protection Techniques for Composite Materials

NASA Technical Reports Server (NTRS)

Szatkowski, George N.; Nguyen, Truong X.; Koppen, Sandra V.; Ely, Jay J.; Mielnik, John J.

2009-01-01

The growing application of composite materials in commercial aircraft manufacturing has significantly increased the risk of aircraft damage from lightning strikes. Composite aircraft designs require new mitigation strategies and engineering practices to maintain the same level of safety and protection as achieved by conductive aluminum skinned aircraft. Researchers working under the NASA Aviation Safety Program s Integrated Vehicle Health Management (IVHM) Project are investigating lightning damage on composite materials to support the development of new mitigation, diagnosis & prognosis techniques to overcome the increased challenges associated with lightning protection on composite aircraft. This paper provides an overview of the electrical characterizations being performed to support IVHM lightning damage diagnosis research on composite materials at the NASA Langley Research Center.

Hospital-Based Comparative Effectiveness Centers: Translating Research into Practice to Improve the Quality, Safety and Value of Patient Care

PubMed Central

Williams, Kendal; Brennan, Patrick J.

2010-01-01

Hospital-based comparative effectiveness (CE) centers provide a model that clinical leaders can use to improve evidence-based practice locally. The model is used by integrated health systems outside the US, but is less recognized in the US. Such centers can identify and adapt national evidence-based policies for the local setting, create local evidence-based policies in the absence of national policies, and implement evidence into practice through health information technology (HIT) and quality initiatives. Given the increasing availability of CE evidence and incentives to meaningfully use HIT, the relevance of this model to US practitioners is increasing. This is especially true in the context of healthcare reform, which will likely reduce reimbursements for care deemed unnecessary by published evidence or guidelines. There are challenges to operating hospital-based CE centers, but many of these challenges can be overcome using solutions developed by those currently leading such centers. In conclusion, these centers have the potential to improve the quality, safety and value of care locally, ultimately translating into higher quality and more cost-effective care nationally. To better understand this potential, the current activity and impact of hospital-based CE centers in the US should be rigorously examined. PMID:20697961

NASA Langley Research Center's Simulation-To-Flight Concept Accomplished through the Integration Laboratories of the Transport Research Facility

NASA Technical Reports Server (NTRS)

Martinez, Debbie; Davidson, Paul C.; Kenney, P. Sean; Hutchinson, Brian K.

2004-01-01

The Flight Simulation and Software Branch (FSSB) at NASA Langley Research Center (LaRC) maintains the unique national asset identified as the Transport Research Facility (TRF). The TRF is a group of facilities and integration laboratories utilized to support the LaRC's simulation-to-flight concept. This concept incorporates common software, hardware, and processes for both groundbased flight simulators and LaRC s B-757-200 flying laboratory identified as the Airborne Research Integrated Experiments System (ARIES). These assets provide Government, industry, and academia with an efficient way to develop and test new technology concepts to enhance the capacity, safety, and operational needs of the ever-changing national airspace system. The integration of the TRF enables a smooth continuous flow of the research from simulation to actual flight test.

FY 1991 safety program status report

NASA Technical Reports Server (NTRS)

1991-01-01

In FY 1991, the NASA Safety Division continued efforts to enhance the quality and productivity of its safety oversight function. Recent initiatives set forth in areas such as training, risk management, safety assurance, operational safety, and safety information systems have matured into viable programs contributing to the safety and success of activities throughout the Agency. Efforts continued to develop a centralized intra-agency safety training program with establishment of the NASA Safety Training Center at the Johnson Space Center (JSC). The objective is to provide quality training for NASA employees and contractors on a broad range of safety-related topics. Courses developed by the Training Center will be presented at various NASA locations to minimize travel and reach the greatest number of people at the least cost. In FY 1991, as part of the ongoing efforts to enhance the total quality of NASA's safety work force, the Safety Training Center initiated development of a Certified Safety Professional review course. This course provides a comprehensive review of the skills and knowledge that well-rounded safety professionals must possess to qualify for professional certification. FY 1992 will see the course presented to NASA and contractor employees at all installations via the NASA Video Teleconference System.

Engaging Stakeholders in Patient-Centered Outcomes Research Regarding School-Based Sealant Programs.

PubMed

Chi, Donald L; Milgrom, Peter; Gillette, Jane

2018-02-01

Purpose: The purpose of this study was to use qualitative methods to describe the key lessons learned during the stakeholder engagement stage of planning a randomized clinical trial comparing outcomes of silver diamine fluoride (SDF) as an alternative to pit-and-fissure sealants in a school-based delivery system. Methods: Eighteen caregivers and community-based stakeholders with involvement in the school-based sealant program Sealants for Smiles from the state of Montana, were recruited for this qualitative study. United States (U.S.) Patient-Centered Outcomes Research Institute (PCORI) methodology standards were used to develop two semi-structured interview guides consisting of 6 questions. One interview guide was used for telephone interviews with caregivers and the second was used for a stakeholder focus group. Content analytic methods were used to analyze the data. Results: All participants believed that a study comparing SDF and sealants was clinically relevant. Non-caregiver stakeholders agreed with the proposed primary outcome of the study (caries prevention) whereas caregivers also emphasized the importance of child-centered outcomes such as minimizing dental anxiety associated with dental care. Stakeholders described potential concerns associated with SDF such as staining and perceptions of safety and discussed ways to address these concerns through community engagement, appropriate framing of the study, proper consent procedures, and ongoing safety monitoring during the trial. Finally, stakeholders suggested dissemination strategies such as direct communication of findings through professional organizations and encouraging insurance plans to incentivize SDF use by reimbursing dental providers. Conclusions: Involving key stakeholders in early planning is essential in developing patient-centered research questions, outcomes measures, study protocols, and dissemination plans for oral health research involving a school-based delivery system. Copyright © 2018 The American Dental Hygienists’ Association.

Providing Quality Therapeutics in Switzerland: Role of the Stakeholders and Recent Incentives for Further Improvements.

PubMed

Besson, Marie; Samer, Caroline; Rollason, Victoria; Dayer, Pierre; Desmeules, Jules

2015-07-01

Quality therapeutics play an important role in Switzerland's health care and economy. Switzerland holds a key position in the world of research and development, as well as in drug production. Recently, new emphasis has been placed on promoting clinical research and maintaining Switzerland's position as a center of excellence in the field. Recent revisions to the law regarding medical trials in human research allow for better allocation of regulatory resources and simplified procedures for drugs already authorized in Switzerland. The country has its own regulatory agency, the Swiss Agency for Therapeutic Products (Swissmedic), which is a public institution of the Swiss government. Swissmedic is responsible for ensuring safety in medicines, particularly regarding authorizations and market surveillance in the sector of medicinal products and medical devices. Although the centralized authorization procedure of the European Union for medicines does not apply to Switzerland, there are mutual recognition mechanisms between the Swiss medicine regulatory authority and the European Medicines Agency. Swissmedic is also in charge of postmarketing safety and oversees the national pharmacovigilance center, which collaborates closely with the World Health Organization center in Uppsala. In addition, university hospital-based clinical pharmacologists, who are involved in basic science and clinical research, regulatory affairs, ethics committees, and pharmacovigilance, promote quality therapeutics. This article discusses the role of the various stakeholders and the recent efforts made to provide a better allocation of resources aimed at further improving quality therapeutics in Switzerland. Copyright © 2015 Elsevier HS Journals, Inc. All rights reserved.

The National Heart, Lung, and Blood Institute Recipient Epidemiology and Donor Evaluation Study (REDS-III): A research program striving to improve blood donor and transfusion recipient outcomes

PubMed Central

Kleinman, Steven; Busch, Michael P; Murphy, Edward L; Shan, Hua; Ness, Paul; Glynn, Simone A.

2014-01-01

Background The Recipient Epidemiology and Donor Evaluation Study -III (REDS-III) is a 7-year multicenter transfusion safety research initiative launched in 2011 by the National Heart, Lung, and Blood Institute. Study design The domestic component involves 4 blood centers, 12 hospitals, a data coordinating center, and a central laboratory. The international component consists of distinct programs in Brazil, China, and South Africa which involve US and in-country investigators. Results REDS-III is using two major methods to address key research priorities in blood banking/transfusion medicine. First, there will be numerous analyses of large “core” databases; the international programs have each constructed a donor/donation database while the domestic program has established a detailed research database that links data from blood donors and their donations, the components made from these donations, and data extracts from the electronic medical records of the recipients of these components. Secondly, there are more than 25 focused research protocols involving transfusion recipients, blood donors, or both that are either in progress or scheduled to begin within the next 3 years. Areas of study include transfusion epidemiology and blood utilization; transfusion outcomes; non-infectious transfusion risks; HIV-related safety issues (particularly in the international programs); emerging infectious agents; blood component quality; donor health and safety; and other donor issues. Conclusions It is intended that REDS-III serve as an impetus for more widespread recipient and linked donor-recipient research in the US as well as to help assure a safe and available blood supply in the US and in international locations. PMID:24188564

NASA is with you when you fly on This Week @NASA - November 21, 2014NASA invited social media members Nov. 18 and 19 to the agency’s Armstrong Flight Research Center for a two-day event highlighting the ways NASA is with you when you fly. The NASA social gave participants an exclusive look at the latest tools and technologies being developed to improve the efficiency, safety and adaptability of air transportation. Also, Next ISS crew trains, 3D printer installed in space, Asteroid capture technology test, Journey to Mars media day and more!

NASA Image and Video Library

2014-11-21

NASA invited social media members Nov. 18 and 19 to the agency’s Armstrong Flight Research Center for a two-day event highlighting the ways NASA is with you when you fly. The NASA social gave participants an exclusive look at the latest tools and technologies being developed to improve the efficiency, safety and adaptability of air transportation. Also, Next ISS crew trains, 3D printer installed in space, Asteroid capture technology test, Journey to Mars media day and more!

Joint NASA/USAF Airborne Field Mill Program - Operation and safety considerations during flights of a Lear 28 airplane in adverse weather

NASA Technical Reports Server (NTRS)

Fisher, Bruce D.; Phillips, Michael R.; Maier, Launa M.

1992-01-01

A NASA Langley Research Center Learjet 28 research airplane was flown in various adverse weather conditions in the vicinity of the NASA Kennedy Space Center from 1990-1992 to measure airborne electric fields during the Joint NASA/USAF Airborne Field Mill Program. The objective of this program was to characterize the electrical activity in various weather phenomena common to the NASA-Kennedy area in order to refine Launch Commit Criteria for natural and triggered lightning. The purpose of the program was to safely relax the existing launch commit criteria, thereby increasing launch availability and reducing the chance for weather holds and delays. This paper discusses the operational conduct of the flight test, including environmental/safety considerations, aircraft instrumentation and modification, test limitations, flight procedures, and the procedures and responsibilities of the personnel in the ground station. Airborne field mill data were collected for all the Launch Commit Criteria during two summer and two winter deployments. These data are now being analyzed.

Safety assessment in primary Mycobacterium tuberculosis smear microscopy centres in Blantyre Malawi: a facility based cross sectional survey.

PubMed

Majamanda, J; Ndhlovu, P; Shawa, I T

2013-12-01

Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is transmitted mainly through aerosolization of infected sputum which puts laboratory workers at risk in spite of the laboratory workers' risk of infection being at 3 to 9 times higher than the general public. Laboratory safety should therefore be prioritized and optimized to provide sufficient safety to laboratory workers. To assess the safety for the laboratory workers in TB primary microscopy centres in Blantyre urban. TB primary microscopy centers in Blantyre urban were assessed in aspects of equipment availability, facility layout, and work practice, using a standardized WHO/AFRO ISO 15189 checklist for the developing countries which sets the minimum safety score at ≥80%. Each center was graded according to the score it earned upon assessment. Only one (1) microscopy center out nine (9) reached the minimum safety requirement. Four (4) centers were awarded 1 star level, four (4) centers were awarded 2 star level and only one (1) center was awarded 3 star level. In Blantyre urban, 89% of the Tuberculosis microscopy centers are failing to provide the minimum safety to the laboratory workers. Government and other stake holders should be committed in addressing the safety challenges of TB microscopy centres in the country to ensure safety for the laboratory workers. It is recommended that the study be conducted at the regional or national level for both public and private laboratories in order to have a general picture of safety in Tb microscopy centres possibly across the country.

21 CFR 80.21 - Request for certification.

Code of Federal Regulations, 2010 CFR

2010-04-01

... (HFS-100), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint...-100), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch... _____ Office of Cosmetics and Colors (HFS-100), Center for Food Safety and Applied Nutrition, Food and Drug...

21 CFR 80.21 - Request for certification.

Code of Federal Regulations, 2011 CFR

2011-04-01

... (HFS-100), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint...-100), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch... _____ Office of Cosmetics and Colors (HFS-100), Center for Food Safety and Applied Nutrition, Food and Drug...

'Picture me healthy': a pilot study using photovoice to explore health perceptions among migrant youth in Beijing, China.

PubMed

Leung, May May; Jun, Jing; Tseng, Anna; Bentley, Margaret

2017-09-01

Globalization has resulted in an influx of migrant families from rural provinces into the urban areas of China. Although the migrant population may live in the same cities as urban residents, they experience different lives because of restricted access to job opportunities, social services, and schools for children. Limited research exists with Chinese rural-to-urban migrant youth, particularly using community-based approaches. This study explored migrant youths' perceptions of their nutrition, physical activity, and health environment, using the community-based participatory research method of photovoice. Twelve migrant youth (6 boys and 6 girls) in Beijing, China, participated in two photovoice assignments focused on personal safety, nutrition, and physical activity. The photographs taken by the youth guided group discussions and semi-structured interviews. Inductive and deductive processes were used to identify codes (ideas emerging from text); similar codes were grouped into themes. Pedestrian safety was the most common personal safety concern. Another safety issue was the excess garbage in the community. Garbage was also a barrier to nutrition and physical activity as it was a food sanitation concern and limited the physical environments where children could play. Schools and community recreation centers were perceived as facilitators of physical activity. However, community centers were also a barrier as a limited number of them caused overcrowding, resulting in safety concerns. Photovoice enables youth to express their health perceptions. Our data provide interesting preliminary insight into the lives of Chinese migrant youth, which could help inform the development of interventions and advocate for positive environmental changes for this marginalized population.

Probing Aircraft Flight Test Hazard Mitigation for the Alternative Fuel Effects on Contrails & Cruise Emissions (ACCESS) Research Team

NASA Technical Reports Server (NTRS)

Kelly, Michael J.

2013-01-01

The Alternative Fuel Effects on Contrails & Cruise Emissions (ACCESS) Project Integration Manager requested in July 2012 that the NASA Engineering and Safety Center (NESC) form a team to independently assess aircraft structural failure hazards associated with the ACCESS experiment and to identify potential flight test hazard mitigations to ensure flight safety. The ACCESS Project Integration Manager subsequently requested that the assessment scope be focused predominantly on structural failure risks to the aircraft empennage raft empennage.

Cockpit Displays for Enhancing Terminal-Area Situational Awareness and Runway Safety

NASA Technical Reports Server (NTRS)

Hyer, Paul V.; Otero, Sharon; Jones, Denise R. (Technical Monitor)

2007-01-01

HUD and PFD displays have been developed to enhance situational awareness and improve runway safety. These displays were designed to seamlessly transition through all phases of flight providing guidance and information to the pilot. This report describes the background of the Langley Research Center (LaRC) HUD and PFD work, the steps required to integrate the displays with those of other LaRC programs, the display characteristics of the several operational modes and the transitional logic governing the transition between displays.

Multi-tiered system of support incorporating the R.E.N.E.W. process and its relationship to perception of school safety and office discipline referrals

NASA Astrophysics Data System (ADS)

Flood, Molly M.

This study examined the relationship between the fidelity of multi-tier school-wide positive behavior interventions and supports (SWPBIS) and staff perception of school safety and office discipline referrals. This research provided a case study on multi-tier supports and interventions, and the RENEW person-centered planning process in an alternative special education center following the implementation of a multi-tier SWPBIS model. Pennsylvania is one of several states looking to adopt an effective Tier III behavioral tool. The research described the results of an analysis of implementation fidelity on a multi-tiered school-wide positive behavior support model developed at a special education center operated by a public school system entity. This research explored the fidelity of SWPBIS implementation; analyzed the relationship of SWPBIS to school climate as measured by staff perceptions and reduction of office discipline referrals (ODR); explored tier III supports incorporating a process Rehabilitation and Empowerment, Natural Supports, Education and Work (RENEW); and investigated the potential sustainability of the RENEW process as a multi-tier system of support. This study investigated staff perceptions on integrated supports between schools and communities and identified the degree of relationship to school risk factors, school protective factors, and office discipline referrals following the building of cooperative partnerships between Systems of Care and Local Education Agencies.

Community-based pedestrian safety training in virtual reality: A pragmatic trial.

PubMed

Schwebel, David C; Combs, Tabitha; Rodriguez, Daniel; Severson, Joan; Sisiopiku, Virginia

2016-01-01

Child pedestrian injuries are a leading cause of mortality and morbidity across the United States and the world. Repeated practice at the cognitive-perceptual task of crossing a street may lead to safer pedestrian behavior. Virtual reality offers a unique opportunity for repeated practice without the risk of actual injury. This study conducted a pre-post within-subjects trial of training children in pedestrian safety using a semi-mobile, semi-immersive virtual pedestrian environment placed at schools and community centers. Pedestrian safety skills among a group of 44 seven- and eight-year-old children were assessed in a laboratory, and then children completed six 15-minute training sessions in the virtual pedestrian environment at their school or community center following pragmatic trial strategies over the course of three weeks. Following training, pedestrian safety skills were re-assessed. Results indicate improvement in delay entering traffic following training. Safe crossings did not demonstrate change. Attention to traffic and time to contact with oncoming vehicles both decreased somewhat, perhaps an indication that training was incomplete and children were in the process of actively learning to be safer pedestrians. The findings suggest virtual reality environments placed in community centers hold promise for teaching children to be safer pedestrians, but future research is needed to determine the optimal training dosage. Copyright © 2015 Elsevier Ltd. All rights reserved.

Looming Discontinuities in U.S. Military Strategy and Defense Planning: Colliding RMAs Necessitate a New Strategy

DTIC Science & Technology

2011-01-01

CARE INFRASTRUCTURE AND TRANSPORTATION INTERNATIONAL AFFAIRS LAW AND BUSINESS NATIONAL SECURITY POPULATION AND AGING PUBLIC SAFETY SCIENCE AND...research was conducted within the International Security and Defense Policy Center of the RAND National Defense Research Institute, a federally funded...Marine Corps, the defense agencies, and the defense Intelligence Community. For more information on the International Security and Defense Policy

Develop a Normative or Descriptive Model of the International/Domestic Civil Aviation Industry. Volume 3.

DTIC Science & Technology

1982-09-30

agencies, and airports, conducting aviation safety related- research and development, and managing and operating the national air space system. At the end of...1978 there were almost 800,000 active FAA certificated , t including slightly over 200,000 student pilots.2 Mechanics, control tower operators, and...U.S., and 107 overseas. The FAA operates and maintains 25 air route traffic control centers, 428 airport traffic control centers, 21 ccmbined stations

Development of a Research Participants’ Perception Survey to Improve Clinical Research

PubMed Central

Yessis, Jennifer L.; Kost, Rhonda G.; Lee, Laura M.; Coller, Barry S.; Henderson, David K.

2012-01-01

Abstract Introduction: Clinical research participants’ perceptions regarding their experiences during research protocols provide outcome‐based insights into the effectiveness of efforts to protect rights and safety, and opportunities to enhance participants’ clinical research experiences. Use of validated surveys measuring patient‐centered outcomes is standard in hospitals, yet no instruments exist to assess outcomes of clinical research processes. Methods: We derived survey questions from data obtained from focus groups comprised of research participants and professionals. We assessed the survey for face/content validity, and privacy/confidentiality protections and fielded it to research participants at 15 centers. We conducted analyses of response rates, sample characteristics, and psychometrics, including survey and item completion and analysis, internal consistency, item internal consistency, criterion‐related validity, and item usefulness. Responses were tested for fit into existing patient‐centered dimensions of care and new clinical research dimensions using Cronbach's alpha coefficient. Results: Surveys were mailed to 18,890 individuals; 4,961 were returned (29%). Survey completion was 89% overall; completion rates exceeded 90% for 88 of 93 evaluable items. Questions fit into three dimensions of patient‐centered care and two novel clinical research dimensions (Cronbach's alpha for dimensions: 0.69–0.85). Conclusions: The validated survey offers a new method for assessing and improving outcomes of clinical research processes. Clin Trans Sci 2012; Volume 5: 452–460 PMID:23253666

Center Director Bridges opens Super Safety and Health Day at KSC.

NASA Technical Reports Server (NTRS)

1999-01-01

Center Director Roy Bridges opens the second Super Safety and Health Day at Kennedy Space Center, an entire day when most normal work activities are suspended to allow personnel to attend safety- and health-related activities. The theme, 'Safety and Health Go Hand in Hand,' emphasized KSC's commitment to place the safety and health of the public, astronauts, employees and space- related resources first and foremost. Events included a keynote address, a panel session about related issues, vendor exhibits, and safety training in work groups. The keynote address and panel session were also broadcast internally over NASA television.

Research Technology

NASA Image and Video Library

1997-02-01

Researchers at the Marshall Space Flight Center (MSFC) have designed, fabricated, and tested the first solar thermal engine, a non-chemical rocket engine that produces lower thrust but has better thrust efficiency than a chemical combustion engine. This photograph shows components for the thermal propulsion engine being laid out prior to assembly. MSFC turned to solar thermal propulsion in the early 1990s due to its simplicity, safety, low cost, and commonality with other propulsion systems. As part of MSFC's Space Transportation Directorate, the Propulsion Research Center serves as a national resource for research of advanced, revolutionary propulsion technologies. The mission is to move the Nation's capabilities beyond the confines of conventional chemical propulsion into an era of aircraft-like access to Earth-orbit, rapid travel throughout the solar system, and exploration of interstellar space.

A PC-based simulation of the National Transonic Facitity's safety microprocessor

NASA Technical Reports Server (NTRS)

Thibodeaux, J. J.; Kilgore, W. A.; Balakrishna, S.

1993-01-01

A brief study was undertaken to demonstrate the feasibility of using a state-of-the-art off-the-shelf high speed personal computer for simulating a microprocessor presently used for wind tunnel safety purposes at Langley Research Center's National Transonic Facility (NTF). Currently, there is no active display of tunnel alarm/alert safety information provided to the tunnel operators, but rather such information is periodically recorded on a process monitoring computer printout. This does not provide on-line situational information nor permit rapid identification of safety operational violations which are able to halt tunnel operations. It was therefore decided to simulate the existing algorithms and briefly evaluate a real-time display which could provide both position and trouble shooting information.

78 FR 37228 - Cooperative Agreement To Support the Western Center for Food Safety

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-20

... Davis main campus and experimental stations provide invaluable access to one of the leading food... sites for experimental trials is instrumental to FDA receiving the most current scientifically validated... facilitate industry compliance with preventive control standards. Information gleaned from this research has...

The NASA Aviation Safety Program: Overview

NASA Technical Reports Server (NTRS)

Shin, Jaiwon

2000-01-01

In 1997, the United States set a national goal to reduce the fatal accident rate for aviation by 80% within ten years based on the recommendations by the Presidential Commission on Aviation Safety and Security. Achieving this goal will require the combined efforts of government, industry, and academia in the areas of technology research and development, implementation, and operations. To respond to the national goal, the National Aeronautics and Space Administration (NASA) has developed a program that will focus resources over a five year period on performing research and developing technologies that will enable improvements in many areas of aviation safety. The NASA Aviation Safety Program (AvSP) is organized into six research areas: Aviation System Modeling and Monitoring, System Wide Accident Prevention, Single Aircraft Accident Prevention, Weather Accident Prevention, Accident Mitigation, and Synthetic Vision. Specific project areas include Turbulence Detection and Mitigation, Aviation Weather Information, Weather Information Communications, Propulsion Systems Health Management, Control Upset Management, Human Error Modeling, Maintenance Human Factors, Fire Prevention, and Synthetic Vision Systems for Commercial, Business, and General Aviation aircraft. Research will be performed at all four NASA aeronautics centers and will be closely coordinated with Federal Aviation Administration (FAA) and other government agencies, industry, academia, as well as the aviation user community. This paper provides an overview of the NASA Aviation Safety Program goals, structure, and integration with the rest of the aviation community.

76 FR 64353 - Request for Public Comment on Draft Document: “Criteria for a Recommended Standard: Occupational...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-18

... Institute for Occupational Safety and Health (NIOSH) of the Centers for Disease Control and Prevention (CDC...: The National Institute for Occupational Safety and Health (NIOSH) of the Centers for Disease Control..., Director, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention...

KSC-03pp0148

NASA Image and Video Library

2003-01-16

KENNEDY SPACE CENTER, FLA. - STS-107 Pilot William "Willie" McCool (center) gets help with his launch and entry suit from the Closeout Crew in the White Room. The environmentally controlled chamber is mated to Space Shuttle Columbia for entry into the Shuttle. In the foreground, left, is Mission Specialist David Brown. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST.

Bibliography of reports on research sponsored by the NRC office of nuclear regulatory research, July--December 1977

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buchanan, J.R.

A bibliography of 198 reports published by contractors of the NRC Office of Nuclear Regulatory Research during the period July through December 1977 is presented along with abstracts from the Nuclear Safety Information Center computer file. The bibliography has been sorted into the subject categories used by NRC to organize the research program. Within the subject categories, the reports are arranged first by contractor organization and then chronologically. A brief description of the NRC research program precedes the bibliography.

Bibliography of reports on research sponsored by the NRC Office of Nuclear Regulatory Research, November 1975--June 1976

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buchanan, J.R.

1976-09-30

A bibliography of 152 reports published by contractors of the NRC Office of Nuclear Regulatory Research during the period November 1975 through June 1976 is presented along with abstracts from the Nuclear Safety Information Center computer file. The bibliography has been sorted into the subject categories used by NRC to organize the research program. Within the subject categories, the reports are sorted by contractor organization and then chronologically. A brief description of the NRC research program precedes the bibliography.

47 CFR 0.192 - Emergency Response Interoperability Center.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Organization Public Safety and Homeland Security Bureau § 0.192 Emergency Response Interoperability Center. (a... Public Safety and Homeland Security Bureau to develop, recommend, and administer policy goals, objectives... and procedures for the 700 MHz public safety broadband wireless network and other public safety...

47 CFR 0.192 - Emergency Response Interoperability Center.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Organization Public Safety and Homeland Security Bureau § 0.192 Emergency Response Interoperability Center. (a... Public Safety and Homeland Security Bureau to develop, recommend, and administer policy goals, objectives... and procedures for the 700 MHz public safety broadband wireless network and other public safety...

Alcohol and highway safety in a public health perspective.

PubMed Central

Dickman, F B

1988-01-01

The Public Health Service and the National Highway Traffic Safety Administration share the responsibility for problems related to injury prevention and control regarding the alcohol-impaired operation of motor vehicles. NHTSA activities have evolved over several decades within a general framework which emphasizes community-based systems. The National Highway Traffic Safety Administration is promoting program activities that stress community-level involvement in problems of alcohol and highway use. The public health approach to the mortality and morbidity resulting from alcohol use and motor vehicle operation entails examining and promoting those activities that address human factors. Techniques for Effective Alcohol Management (TEAM) is a cooperative effort representing sports, entertainment, insurance, vehicle manufacturer, and other organizations and agencies building community coalitions. The Centers for Disease Control is establishing research and collaborating centers to stimulate studies and exchange information on injury-related research. Alcohol countermeasures programs include training for law enforcement and legal officials, technology development efforts, and changes in laws applied to use of alcohol and other drugs. Outreach and networking activities have encouraged the initiation and coordination of community level groups active in promoting highway safety with regard to the use of alcohol. Statistical method changes are being discussed for surveillance of motor vehicle-related injuries for Health Objectives for the Nation for the Year 2000. NHTSA data systems being discussed are thought to be more timely and more sensitive to crash activity than methods now in use.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:3141961

An innovative approach to interdisciplinary occupational safety and health education.

PubMed

Rosen, Mitchel A; Caravanos, Jack; Milek, Debra; Udasin, Iris

2011-07-01

The New York and New Jersey Education and Research Center (ERC) provides a range of graduate continuing education for occupational safety and health (OSH) professionals in training. A key element of the education is to provide interdisciplinary training to industrial hygienists, ergonomists, occupational medicine physicians and other health and safety trainees to prepare them for the collaboration required to solve the complex occupational health and safety problems they will face in their careers. This center has developed an innovative interdisciplinary training approach that provides an historical aspect, while allowing the graduate students to identify solutions to occupational issues from a multi-disciplinary approach. The ERC developed a tour that brings students to sites of historical and/or contemporary significance in the occupational safety and health and environmental fields. The ERC has conducted five tours, and has included 85 students and residents as participants. 80% of participants rated the tour as providing a high amount of OSH knowledge gained. 98% of the participants felt the goal of providing interdisciplinary education was achieved. This tour has been successful in bridging the OSH fields to better understand how occupational and environmental exposures have occurred, in order to prevent future exposures so that workplace conditions and health can be improved. Copyright © 2011 Wiley-Liss, Inc.

Media Messages and Tools to Reduce Serious Single Vehicle Run-Off-the-Road Crashes Resulting from Impaired Driving

DOT National Transportation Integrated Search

2012-09-01

The Center for Health and Safety Culture conducted research for the Idaho Transportation Department to develop media messages and tools to reduce fatalities and serious injuries related to Run-Off-the-Road, single-vehicle crashes in Idaho using the P...

Pediatric clinical trial studies antibody treatment for various types of solid tumors | Center for Cancer Research

Cancer.gov

A clinical trial for pediatric patients will test the safety and efficacy of enoblituzumab in solid tumors that express a specific protein, including neuroblastoma, rhabdomyosarcoma, osteosarcoma, Ewing sarcoma, Wilms tumor, or desmoplastic small round cell tumor. Read more... 

Integrating Biopsychosocial Intervention Research in a Changing Health Care Landscape

ERIC Educational Resources Information Center

Ell, Kathleen; Oh, Hyunsung; Wu, Shinyi

2016-01-01

Objective: Safety net care systems are experiencing unprecedented change from the "Affordable Care Act," Patient-Centered Medical Home (PCMH) uptake, health information technology application, and growing of mental health care integration within primary care. This article provides a review of previous and current efforts in which social…

EVALUATION OF WATER MONITORING INSTRUMENTATION AT EPA'S WATER AWARENESS TECHNOLOGY EVALUATION RESEARCH SECURITY CENTER

EPA Science Inventory

The safety and security of distribution systems has come under reassessment in the past year. Several chemical and biological agents have been identified that might constitute a credible threat against water supply systems. There have also been a few reported threats against wate...

Intimate Partner Survivors' Help-Seeking and Protection Efforts: A Person-Oriented Analysis

ERIC Educational Resources Information Center

Nurius, Paula S.; Macy, Rebecca J.; Nwabuzor, Ijeoma; Holt, Victoria L.

2011-01-01

Domestic violence advocates and researchers advocate for a survivor-centered approach for assisting women experiencing intimate partner violence (IV), with individualized safety plans and services; yet little empirical work has been done to determine IV survivors' specific combinations of vulnerabilities and assets that might inform such an…

NWS Turn Around Don't Drown Program, Signs and Resources

Science.gov Websites

Temperatures Records Astronomical Data WEATHER SAFETY Safety Campaigns Air Quality Cold Drought Floods Fog Heat Wind Safety Wildland Fires Winter Weather INFORMATION CENTER Weather-Ready Nation StormReady Centers Products and Services Contact Us Glossary flood navigation bar-top Flood Safety Flood Safety Flood

Shock Absorbing System

NASA Technical Reports Server (NTRS)

1982-01-01

A lightweight, inexpensive shock-absorbing system, developed by Langley Research Center 20 years ago, is now in service as safety device for an automated railway at Duke University Medical Center. The transportation system travels at about 25 miles per hour, carrying patients, visitors, staff and cargo. At the end of each guideway of the system are "frangible," (breakable) tube "buffers." If a slowing car fails to make a complete stop at the terminal, it would bump and shatter the tubes, absorbing energy that might otherwise jolt the passengers or damage the vehicle.

Research and Development in Support of the Navy Technology Center for Safety and Survivability

DTIC Science & Technology

1990-10-26

Patterson AFB, OH. W. E.; Naegeli , D. W.; Valtierra, M. L. An Alternate Test Proce-Black, B. H, M.S. Thesis, Southeastern Massachusetts University, dure to...Cuellar, Jr., J. P.; Dodge, L. G.; Likos, W. E.; Naegeli , D. W.; Valtierra, M. L. "An Alternative Test Procedure to Qualify Fuels for Navy Aircraft...Likos, W.E., Naegeli , D.W., Valtierra, M.L.; "An Alternative Test Proure to Qualify Fuels for Navy Aircraft," Final Report, Naval Air Propulsion Center

Clinical trial uses combination therapy for certain types of non-Hodgkin lymphoma | Center for Cancer Research

Cancer.gov

Researchers are testing the safety of the combination of an experimental drug with rituximab, a standard treatment, for patients with indolent or diffuse large B-cell lymphoma. The antibody is designed to target and block a protein that is present on cancer cells and is used by those cells to protect themselves from your body’s immune system. Blocking the protein may enable

77 FR 73541 - Safety Zone: Gilmerton Bridge Center Span Float-in, Elizabeth River; Norfolk, Portsmouth, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-11

...-AA00 Safety Zone: Gilmerton Bridge Center Span Float-in, Elizabeth River; Norfolk, Portsmouth, and... Gilmerton Bridge Center Span Float- in and bridge construction of span placement. This action is intended to... rulemaking (NPRM) proposing a safety zone in the Gilmerton Bridge Area (77 FR 43557) on September 5-9, 2012...

To make or buy patient safety solutions: a resource dependence and transaction cost economics perspective.

PubMed

Fareed, Naleef; Mick, Stephen S

2011-01-01

For almost a decade, public and private organizations have pressured hospitals to improve their patient safety records. Since 2008, the Centers for Medicare & Medicaid Services has no longer been reimbursing hospitals for secondary diagnoses not reported during the point of admission. This ruling has motivated some hospitals to engage in safety-oriented programs to decrease adverse events. This study examined which hospitals may engage in patient safety solutions and whether they create these patient safety solutions within their structures or use suppliers in the market. We used a theoretical model that incorporates the key constructs of resource dependence theory and transaction cost economics theory to predict a hospital's reaction to Centers for Medicare & Medicaid Services "never event" regulations. We present propositions that speculate on how forces conceptualized from the resource dependence theory may affect adoption of patient safety innovations and, when they do, whether the adopting hospitals will do so internally or externally according to the transaction cost economics theory. On the basis of forces identified by the resource dependence theory, we predict that larger, teaching, safety net, horizontally integrated, highly interdependent, and public hospitals in concentrated, high public payer presence, competitive, and resource-rich environments will be more likely to engage in patient safety innovations. Following the logic of the transaction cost economics theory, we predict that of the hospitals that react positively to the never event regulation, most will internalize their innovations in patient safety solutions rather than approach the market, a choice that helps hospitals economize on transaction costs. This study helps hospital managers in their strategic thinking and planning in relation to current and future regulations related to patient safety. For researchers and policy analysts, our propositions provide the basis for empirical testing.

Recruiting community health centers into pragmatic research: Findings from STOP CRC.

PubMed

Coronado, Gloria D; Retecki, Sally; Schneider, Jennifer; Taplin, Stephen H; Burdick, Tim; Green, Beverly B

2016-04-01

Challenges of recruiting participants into pragmatic trials, particularly at the level of the health system, remain largely unexplored. As part of Strategies and Opportunities to STOP Colon Cancer in Priority Populations (STOP CRC), we recruited eight separate community health centers (consisting of 26 individual safety net clinics) into a large comparative effectiveness pragmatic study to evaluate methods of raising the rates of colorectal cancer screening. In partnership with STOP CRC's advisory board, we defined criteria to identify eligible health centers and applied these criteria to a list of health centers in Washington, Oregon, and California affiliated with Oregon Community Health Information Network, a 16-state practice-based research network of federally sponsored health centers. Project staff contacted centers that met eligibility criteria and arranged in-person meetings of key study investigators with health center leadership teams. We used the Consolidated Framework for Implementation Research to thematically analyze the content of discussions during these meetings to identify major facilitators of and barriers to health center participation. From an initial list of 41 health centers, 11 met the initial inclusion criteria. Of these, leaders at three centers declined and at eight centers (26 clinic sites) agreed to participate (73%). Participating and nonparticipating health centers were similar with respect to clinic size, percent Hispanic patients, and percent uninsured patients. Participating health centers had higher proportions of Medicaid patients and higher baseline colorectal cancer screening rates. Common facilitators of participation were perception by center leadership that the project was an opportunity to increase colorectal cancer screening rates and to use electronic health record tools for population management. Barriers to participation were concerns of center leaders about ability to provide fecal testing to and assure follow-up of uninsured patients, limited clinic capacity to prepare mailings required by the study protocol, discomfort with randomization, and concerns about delaying program implementation at some clinics due to the research requirements. Our findings address an important research gap and may inform future efforts to recruit community health centers into pragmatic research. © The Author(s) 2015.

Recruiting community health centers into pragmatic research: Findings from STOP CRC

PubMed Central

Coronado, Gloria D; Retecki, Sally; Schneider, Jennifer; Taplin, Stephen H; Burdick, Tim; Green, Beverly B

2015-01-01

Background Challenges of recruiting participants into pragmatic trials, particularly at the level of the health system, remain largely unexplored. As part of Strategies and Opportunities to STOP Colon Cancer in Priority Populations (STOP CRC), we recruited eight separate community health centers (consisting of 26 individual safety net clinics) into a large comparative effectiveness pragmatic study to evaluate methods of raising the rates of colorectal cancer screening. Methods In partnership with STOP CRC’s advisory board, we defined criteria to identify eligible health centers and applied these criteria to a list of health centers in Washington, Oregon, and California affiliated with OCHIN (formerly Oregon Community Health Information Network), a 16-state practice-based research network of federally sponsored health centers. Project staff contacted centers that met eligibility criteria and arranged in-person meetings of key study investigators with health center leadership teams. We used the Consolidated Framework for Implementation Research to thematically analyze the content of discussions during these meetings to identify major facilitators of and barriers to health center participation. Results From an initial list of 41 health centers, 11 met the initial inclusion criteria. Of these, leaders at three centers declined and at eight centers (26 clinic sites) agreed to participate (73%). Participating and nonparticipating health centers were similar with respect to clinic size, percent Hispanic patients, and percent uninsured patients. Participating health centers had higher proportions of Medicaid patients and higher baseline colorectal cancer screening rates. Common facilitators of participation were perception by center leadership that the project was an opportunity to increase colorectal cancer screening rates and to use electronic health record tools for population management. Barriers to participation were concerns of center leaders about ability to provide fecal testing to and assure follow up of uninsured patients, limited clinic capacity to prepare mailings required by the study protocol, discomfort with randomization, and concerns about delaying program implementation at some clinics due to the research requirements. Conclusion Our findings address an important research gap and may inform future efforts to recruit community health centers into pragmatic research. PMID:26419905

Air Breathing Propulsion Controls and Diagnostics Research at NASA Glenn Under NASA Aeronautics Research Mission Programs

NASA Technical Reports Server (NTRS)

Garg, Sanjay

2014-01-01

The Intelligent Control and Autonomy Branch (ICA) at NASA (National Aeronautics and Space Administration) Glenn Research Center (GRC) in Cleveland, Ohio, is leading and participating in various projects in partnership with other organizations within GRC and across NASA, the U.S. aerospace industry, and academia to develop advanced controls and health management technologies that will help meet the goals of the NASA Aeronautics Research Mission Directorate (ARMD) Programs. These efforts are primarily under the various projects under the Fundamental Aeronautics Program (FAP) and the Aviation Safety Program (ASP). The ICA Branch is focused on advancing the state-of-the-art of aero-engine control and diagnostics technologies to help improve aviation safety, increase efficiency, and enable operation with reduced emissions. This paper describes the various ICA research efforts under the NASA Aeronautics Research Mission Programs with a summary of motivation, background, technical approach, and recent accomplishments for each of the research tasks.

Air Breathing Propulsion Controls and Diagnostics Research at NASA Glenn Under NASA Aeronautics Research Mission Programs

NASA Technical Reports Server (NTRS)

Garg, Sanjay

2015-01-01

The Intelligent Control and Autonomy Branch (ICA) at NASA (National Aeronautics and Space Administration) Glenn Research Center (GRC) in Cleveland, Ohio, is leading and participating in various projects in partnership with other organizations within GRC and across NASA, the U.S. aerospace industry, and academia to develop advanced controls and health management technologies that will help meet the goals of the NASA Aeronautics Research Mission Directorate (ARMD) Programs. These efforts are primarily under the various projects under the Advanced Air Vehicles Program (AAVP), Airspace Operations and Safety Program (AOSP) and Transformative Aeronautics Concepts Program (TAC). The ICA Branch is focused on advancing the state-of-the-art of aero-engine control and diagnostics technologies to help improve aviation safety, increase efficiency, and enable operation with reduced emissions. This paper describes the various ICA research efforts under the NASA Aeronautics Research Mission Programs with a summary of motivation, background, technical approach, and recent accomplishments for each of the research tasks.

Nuclear Safety Information Center, Its Products and Services

ERIC Educational Resources Information Center

Buchanan, J. R.

1970-01-01

The Nuclear Safety Information Center (NSIC) serves as a focal point for the collection, analysis and dissemination of information related to safety problems encountered in the design, analysis, and operation of nuclear facilities. (Author/AB)

Results From the John Glenn Biomedical Engineering Consortium. A Success Story for NASA and Northeast Ohio

NASA Technical Reports Server (NTRS)

Nall, Marsha M.; Barna, Gerald J.

2009-01-01

The John Glenn Biomedical Engineering Consortium was established by NASA in 2002 to formulate and implement an integrated, interdisciplinary research program to address risks faced by astronauts during long-duration space missions. The consortium is comprised of a preeminent team of Northeast Ohio institutions that include Case Western Reserve University, the Cleveland Clinic, University Hospitals Case Medical Center, The National Center for Space Exploration Research, and the NASA Glenn Research Center. The John Glenn Biomedical Engineering Consortium research is focused on fluid physics and sensor technology that addresses the critical risks to crew health, safety, and performance. Effectively utilizing the unique skills, capabilities and facilities of the consortium members is also of prime importance. Research efforts were initiated with a general call for proposals to the consortium members. The top proposals were selected for funding through a rigorous, peer review process. The review included participation from NASA's Johnson Space Center, which has programmatic responsibility for NASA's Human Research Program. The projects range in scope from delivery of prototype hardware to applied research that enables future development of advanced technology devices. All of the projects selected for funding have been completed and the results are summarized. Because of the success of the consortium, the member institutions have extended the original agreement to continue this highly effective research collaboration through 2011.

The International C2 Journal, Volume 2 Number 1, 2008. Special Issue: Awareness. Tightly Coupling Cognition: Understanding How Communication and Awareness Drive Coordination in Teams

DTIC Science & Technology

2008-01-01

such organizational configurations are high so are the consequences for failure. From decades of research on teams and team or group problem solving...TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Office of Naval Research ,One Liberty Center,875 North Randolph...Naval Postgraduate School Ross Pigeau (CAN), Defence Research and Development Canada (DRDC) Mink Spaans (NED), TNO Defence, Security and Safety About

Selected Examples of NACA/NASA Supersonic Flight Research

NASA Technical Reports Server (NTRS)

Saltzman, Edwin J.; Ayers, Theodore G.

1995-01-01

The present Dryden Flight Research Center, a part of the National Aeronautics and Space Administration, has a flight research history that extends back to the mid-1940's. The parent organization was a part of the National Advisory Committee for Aeronautics and was formed in 1946 as the Muroc Flight Test Unit. This document describes 13 selected examples of important supersonic flight research conducted from the Mojave Desert location of the Dryden Flight Research Center over a 4 decade period beginning in 1946. The research described herein was either obtained at supersonic speeds or enabled subsequent aircraft to penetrate or traverse the supersonic region. In some instances there accrued from these research efforts benefits which are also applicable at lower or higher speed regions. A major consideration in the selection of the various research topics was the lasting impact they have had, or will have, on subsequent supersonic flight vehicle design, efficiency, safety, and performance or upon improved supersonic research techniques.

The 2016 Academic Emergency Medicine Consensus Conference, Shared Decision Making in the Emergency Department: Development of a Policy-relevant Patient-centered Research Agenda May 10, 2016, New Orleans, LA.

PubMed

Grudzen, Corita R; Anderson, Jana R; Carpenter, Christopher R; Hess, Erik P

2016-12-01

Shared decision making in emergency medicine has the potential to improve the quality, safety, and outcomes of emergency department (ED) patients. Given that the ED is the gateway to care for patients with a variety of illnesses and injuries and the safety net for patients otherwise unable to access care, shared decision making in the ED is relevant to numerous disciplines and the interests of the United States (U.S.) public. On May 10, 2016 the 16th annual Academic Emergency Medicine (AEM) consensus conference, "Shared Decision Making: Development of a Policy-Relevant Patient-Centered Research Agenda" was held in New Orleans, Louisiana. During this one-day conference clinicians, researchers, policy-makers, patient and caregiver representatives, funding agency representatives, trainees, and content experts across many areas of medicine interacted to define high priority areas for research in 1 of 6 domains: 1) diagnostic testing; 2) policy, 3) dissemination/implementation and education, 4) development and testing of shared decision making approaches and tools in practice, 5) palliative care and geriatrics, and 6) vulnerable populations and limited health literacy. This manuscript describes the current state of shared decision making in the ED context, provides an overview of the conference planning process, the aims of the conference, the focus of each respective breakout session, the roles of patient and caregiver representatives and an overview of the conference agenda. The results of this conference published in this issue of AEM provide an essential summary of the future research priorities for shared decision making to increase quality of care and patient-centered outcomes. © 2016 by the Society for Academic Emergency Medicine.

NASA's Human Research Program at The Glenn Research Center: Progress and Opportunities

NASA Technical Reports Server (NTRS)

Nall, Marsha; Griffin, DeVon; Myers, Jerry; Perusek, Gail

2008-01-01

The NASA Human Research Program is aimed at correcting problems in critical areas that place NASA human spaceflight missions at risk due to shortfalls in astronaut health, safety and performance. The Glenn Research Center (GRC) and partners from Ohio are significant contributors to this effort. This presentation describes several areas of GRC emphasis, the first being NASA s path to creating exercise hardware requirements and protocols that mitigate the effects of long duration spaceflight. Computational simulations will be a second area that is discussed. This includes deterministic models that simulate the effects of spaceflight on the human body, as well as probabilistic models that bound and quantify the probability that adverse medical incidents will happen during an exploration mission. Medical technology development for exploration will be the final area to be discussed.

21 CFR Appendix A to Part 101 - Monier-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and...

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Monier-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and Applied Nutrition, Food and Drug Administration (November 1985...-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and Applied Nutrition...

21 CFR Appendix A to Part 101 - Monier-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Monier-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and Applied Nutrition, Food and Drug Administration (November 1985...-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and Applied Nutrition...

21 CFR Appendix A to Part 101 - Monier-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and...

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Monier-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and Applied Nutrition, Food and Drug Administration (November 1985...-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and Applied Nutrition...

21 CFR Appendix A to Part 101 - Monier-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Monier-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and Applied Nutrition, Food and Drug Administration (November 1985...-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and Applied Nutrition...

21 CFR Appendix A to Part 101 - Monier-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and...

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Monier-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and Applied Nutrition, Food and Drug Administration (November 1985...-Williams Procedure (With Modifications) for Sulfites in Food, Center for Food Safety and Applied Nutrition...

Career Profile: Flight Operations Engineer (Airborne Science) Robert Rivera

NASA Image and Video Library

2015-05-14

Operations engineers at NASA's Armstrong Flight Research Center help to advance science, technology, aeronautics, and space exploration by managing operational aspects of a flight research project. They serve as the governing authority on airworthiness related to the modification, operation, or maintenance of specialized research or support aircraft so those aircraft can be flown safely without jeopardizing the pilots, persons on the ground or the flight test project. With extensive aircraft modifications often required to support new research and technology development efforts, operations engineers are key leaders from technical concept to flight to ensure flight safety and mission success. Other responsibilities of an operations engineer include configuration management, performing systems design and integration, system safety analysis, coordinating flight readiness activities, and providing real-time flight support. This video highlights the responsibilities and daily activities of NASA Armstrong operations engineer Robert Rivera during the preparation and execution of the Global Hawk airborne missions under NASA's Science Mission Directorate.

Patient Safety Threat - Syringe Reuse

MedlinePlus

... Fingerstick Devices Clinical Reminder: Insulin Pens Publications Infection Control Assessment of Ambulatory Surgical Centers Meetings Insurance Stakeholders Meeting – December 2011 Ambulatory Surgical Centers – October 2010 Safety by Design – May 2010 Sticking with Safety – May 2010 Injection ...

KENNEDY SPACE CENTER, FLA. - Before the start of the kickoff presentation for Spaceport Super Safety and Health Day, Center Director Jim Kennedy (left) chats with guest speaker Capt. Charles Plumb (USNR retired) and United Space Alliance Vice President and Deputy Program Manager, Florida Operations, Bill Pickavance. Spaceport Super Safety and Health Day is an annual event at KSC and Cape Canaveral Air Force Station dedicated to reinforcing safe and healthful behaviors in the workforce. Safety Awards were also given to individuals and groups.

NASA Image and Video Library

2003-10-15

KENNEDY SPACE CENTER, FLA. - Before the start of the kickoff presentation for Spaceport Super Safety and Health Day, Center Director Jim Kennedy (left) chats with guest speaker Capt. Charles Plumb (USNR retired) and United Space Alliance Vice President and Deputy Program Manager, Florida Operations, Bill Pickavance. Spaceport Super Safety and Health Day is an annual event at KSC and Cape Canaveral Air Force Station dedicated to reinforcing safe and healthful behaviors in the workforce. Safety Awards were also given to individuals and groups.

Optimizing Safety, Fidelity and Usability of an Intelligent Clinical Support Tool (ICST) For Acute Hospital Care: an Australian Case Study Using a Multi-Method Delphi Process.

PubMed

Botti, Mari; Redley, Bernice; Nguyen, Lemai; Coleman, Kimberley; Wickramasinghe, Nilmini

2015-01-01

This research focuses on a major health priority for Australia by addressing existing gaps in the implementation of nursing informatics solutions in healthcare. It serves to inform the successful deployment of IT solutions designed to support patient-centered, frontline acute healthcare delivery by multidisciplinary care teams. The outcomes can guide future evaluations of the contribution of IT solutions to the efficiency, safety and quality of care delivery in acute hospital settings.

Improving Safety and Reliability of Space Auxiliary Power Units

NASA Technical Reports Server (NTRS)

Viterna, Larry A.

1998-01-01

Auxiliary Power Units (APU's) play a critical role in space vehicles. On the space shuttle, APU's provide the hydraulic power for the aerodynamic control surfaces, rocket engine gimballing, landing gear, and brakes. Future space vehicles, such as the Reusable Launch Vehicle, will also need APU's to provide electrical power for flight control actuators and other vehicle subsystems. Vehicle designers and mission managers have identified safety, reliability, and maintenance as the primary concerns for space APU's. In 1997, the NASA Lewis Research Center initiated an advanced technology development program to address these concerns.

Technology and Tool Development to Support Safety and Mission Assurance

NASA Technical Reports Server (NTRS)

Denney, Ewen; Pai, Ganesh

2017-01-01

The Assurance Case approach is being adopted in a number of safety-mission-critical application domains in the U.S., e.g., medical devices, defense aviation, automotive systems, and, lately, civil aviation. This paradigm refocuses traditional, process-based approaches to assurance on demonstrating explicitly stated assurance goals, emphasizing the use of structured rationale, and concrete product-based evidence as the means for providing justified confidence that systems and software are fit for purpose in safely achieving mission objectives. NASA has also been embracing assurance cases through the concepts of Risk Informed Safety Cases (RISCs), as documented in the NASA System Safety Handbook, and Objective Hierarchies (OHs) as put forth by the Agency's Office of Safety and Mission Assurance (OSMA). This talk will give an overview of the work being performed by the SGT team located at NASA Ames Research Center, in developing technologies and tools to engineer and apply assurance cases in customer projects pertaining to aviation safety. We elaborate how our Assurance Case Automation Toolset (AdvoCATE) has not only extended the state-of-the-art in assurance case research, but also demonstrated its practical utility. We have successfully developed safety assurance cases for a number of Unmanned Aircraft Systems (UAS) operations, which underwent, and passed, scrutiny both by the aviation regulator, i.e., the FAA, as well as the applicable NASA boards for airworthiness and flight safety, flight readiness, and mission readiness. We discuss our efforts in expanding AdvoCATE capabilities to support RISCs and OHs under a project recently funded by OSMA under its Software Assurance Research Program. Finally, we speculate on the applicability of our innovations beyond aviation safety to such endeavors as robotic, and human spaceflight.

Explore The NASA Safety Center

NASA Image and Video Library

2015-07-01

The NASA Safety Center (NSC) reports to NASA’s Office of Safety and Mission Assurance and supports the Safety and Mission Assurance (SMA) requirements of NASA’s portfolio of programs and projects. The NSC focuses on development of the personnel, processes and tools needed for the safe and successful achievement of NASA’s strategic goals.

University building safety index measurement using risk and implementation matrix

NASA Astrophysics Data System (ADS)

Rahman, A.; Arumsari, F.; Maryani, A.

2018-04-01

Many high rise building constructed in several universities in Indonesia. The high-rise building management must provide the safety planning and proper safety equipment in each part of the building. Unfortunately, most of the university in Indonesia have not been applying safety policy yet and less awareness on treating safety facilities. Several fire accidents in university showed that some significant risk should be managed by the building management. This research developed a framework for measuring the high rise building safety index in university The framework is not only assessed the risk magnitude but also designed modular building safety checklist for measuring the safety implementation level. The safety checklist has been developed for 8 types of the university rooms, i.e.: office, classroom, 4 type of laboratories, canteen, and library. University building safety index determined using risk-implementation matrix by measuring the risk magnitude and assessing the safety implementation level. Building Safety Index measurement has been applied in 4 high rise buildings in ITS Campus. The building assessment showed that the rectorate building in secure condition and chemical department building in beware condition. While the library and administration center building was in less secure condition.

Toxic substances alert program

NASA Technical Reports Server (NTRS)

Junod, T. L.

1978-01-01

A toxicity profile is provided, of 187 toxic substances procured by NASA Lewis Research Center during a 3 1/2 year period, including 27 known or suspected carcinogens. The goal of the program is to assure that the center's health and safety personnel are aware of the procurement and use of toxic substances and to alert and inform the users of these materials as to the toxic characteristics and the control measures needed to ensure their safe use. The program also provides a continuing record of the toxic substances procured, who procured them, what other toxic substances the user has obtained in the past, and where similar materials have been used elsewhere at the center.

KSC All Hands

NASA Image and Video Library

2018-01-11

Russ DeLoach, director of Safety and Mission Assurance, speaks to Kennedy Space Center employees about plans for the coming year. The event took place in the Lunar Theater at the Kennedy Space Center Visitor Complex’s Apollo Saturn V Center. The year will be highlighted with NASA's partners preparing test flights for crewed missions to the International Space Station as part of the agency's Commercial Crew Program and six launches by the Launch Services Program. Exploration Ground Systems will be completing facilities to support the Space Launch System rocket and Orion spacecraft. Exploration Research and Technology Programs will continue to provide supplies to the space station launched as part of the Commercial Resupply Services effort.

First NASA Workshop on Wiring for Space Applications

NASA Technical Reports Server (NTRS)

Hammond, Ahmad (Compiler); Stavnes, Mark W. (Compiler)

1994-01-01

This document contains the proceedings of the First NASA Workshop on Wiring for Space Applications held at NASA Lewis Research Center in Cleveland, OH, July 23-24, 1991. The workshop was sponsored by NASA Headquarters Code QE Office of Safety and Mission Quality, Technical Standards Division and hosted by the NASA Lewis Research Center, Power Technology Division, Electrical Components and Systems Branch. The workshop addressed key technology issues in the field of electrical power wiring for space applications. Speakers from government, industry and academia presented and discussed topics on arc tracking phenomena, wiring applications and requirements, and new candidate insulation materials and constructions. Presentation materials provided by the various speakers are included in this document.

Safety climate and workplace violence prevention in state-run residential addiction treatment centers.

PubMed

Lipscomb, Jane A; London, M; Chen, Y M; Flannery, K; Watt, M; Geiger-Brown, J; Johnson, J V; McPhaul, K

2012-01-01

To examine the association between violence prevention safety climate measures and self reported violence toward staff in state-run residential addiction treatment centers. In mid-2006, 409 staff from an Eastern United States state agency that oversees a system of thirteen residential addiction treatment centers (ATCs) completed a self-administered survey as part of a comprehensive risk assessment. The survey was undertaken to identify and measure facility-level risk factors for violence, including staff perceptions of the quality of existing US Occupational Safety and Health Administration (OSHA) program elements, and ultimately to guide violence prevention programming. Key informant interviews and staff focus groups provided researchers with qualitative data with which to understand safety climate and violence prevention efforts within these work settings. The frequency with which staff reported experiencing violent behavior ranged from 37% for "clients raised their voices in a threatening way to you" to 1% for "clients pushed, hit, kicked, or struck you". Findings from the staff survey included the following significant predictors of violence: "client actively resisting program" (OR=2.34, 95% CI=1.35, 4.05), "working with clients for whom the history of violence is unknown" (OR=1.91, 95% CI=1.18, 3.09) and "management commitment to violence prevention" reported as "never/hardly ever" and "seldom or sometimes" (OR=4.30 and OR=2.31 respectively), while controlling for other covariates. We utilized a combination of qualitative and quantitative research methods to begin to describe the risk and potential for violence prevention in this setting. The prevalence of staff physical violence within the agency's treatment facilities was lower than would be predicted. Possible explanations include the voluntary nature of treatment programs; strong policies and consequences for resident behavior and ongoing quality improvement efforts. Quantitative data identified low management commitment to violence prevention as a significant predictor of staff reported violence.

Diabetes and Hypertension Quality Measurement in Four Safety-Net Sites

PubMed Central

Benkert, R.; Dennehy, P.; White, J.; Hamilton, A.; Tanner, C.

2014-01-01

Summary Background In this new era after the Health Information Technology for Economic and Clinical Health (HITECH) Act of 2009, the literature on lessons learned with electronic health record (EHR) implementation needs to be revisited. Objectives Our objective was to describe what implementation of a commercially available EHR with built-in quality query algorithms showed us about our care for diabetes and hypertension populations in four safety net clinics, specifically feasibility of data retrieval, measurements over time, quality of data, and how our teams used this data. Methods A cross-sectional study was conducted from October 2008 to October 2012 in four safety-net clinics located in the Midwest and Western United States. A data warehouse that stores data from across the U.S was utilized for data extraction from patients with diabetes or hypertension diagnoses and at least two office visits per year. Standard quality measures were collected over a period of two to four years. All sites were engaged in a partnership model with the IT staff and a shared learning process to enhance the use of the quality metrics. Results While use of the algorithms was feasible across sites, challenges occurred when attempting to use the query results for research purposes. There was wide variation of both process and outcome results by individual centers. Composite calculations balanced out the differences seen in the individual measures. Despite using consistent quality definitions, the differences across centers had an impact on numerators and denominators. All sites agreed to a partnership model of EHR implementation, and each center utilized the available resources of the partnership for Center-specific quality initiatives. Conclusions Utilizing a shared EHR, a Regional Extension Center-like partnership model, and similar quality query algorithms allowed safety-net clinics to benchmark and improve the quality of care across differing patient populations and health care delivery models. PMID:25298815

Unveiling of sign for Walter C. Williams Research Aircraft Integration Facility

NASA Technical Reports Server (NTRS)

1995-01-01

In a brief ceremony following a memorial service for the late Walter C. Williams on November 17, 1995, the Integrated Test Facility (ITF) at the NASA Dryden Flight Research Center at Edwards, California, was formally renamed the Walter C. Williams Research Aircraft Integration Facility. Shown is the family of Walt Williams: Helen, his widow, sons Charles and Howard, daughter Elizabeth Williams Powell, their spouses and children unveiling the new sign redesignating the Facility. The test facility provides state-of-the-art capabilities for thorough ground testing of advanced research aircraft. It allows researchers and technicians to integrate and test aircraft systems before each research flight, which greatly enhances the safety of each mission. In September 1946 Williams became engineer-in-charge of a team of five engineers who arrived at Muroc Army Air Base (now Edwards AFB) from the National Advisory Committee for Aeronautics's Langley Memorial Aeronautical Laboratory, Hampton, Virginia (now NASA's Langley Research Center), to prepare for supersonic research flights in a joint NACA-Army Air Forces program involving the rocket-powered X-1. This established the first permanent NACA presence at the Mojave Desert site although initially the five engineers and others who followed them were on temporary assignment. Over time, Walt continued to be in charge during the many name changes for the NACA-NASA organization, with Williams ending his stay as Chief of the NASA Flight Research Center in September 1959 (today NASA's Dryden Flight Research Center).

Complexity and Safety (FAA)

DTIC Science & Technology

2016-10-27

Software Engineering Institute Carnegie Mellon University Pittsburgh, PA 15213 © 2016 Carnegie Mellon University [DISTRIBUTION STATEMENT A: This... Carnegie Mellon University [DISTRIBUTION STATEMENT A: This material has been approved for public release and unlimited distribution] Copyright 2016 Carnegie ... Carnegie Mellon University for the operation of the Software Engineering Institute, a federally funded research and development center sponsored by

Clinical trial studies safety and efficacy of adding a kinase inhibitor to chemotherapy with topotecan in small cell lung cancer | Center for Cancer Research

Cancer.gov

Dr. Anish Thomas, Staff Clinician in the Thoracic and Gastrointestinal Oncology Branch (TGIB), is leading a trial of combination therapy in small cell lung cancer (SCLC), a fast-growing malignancy that occurs most commonly in smokers. Learn more...

Nonthermal processing technologies to improve the safety of raw meat and poultry products and ready-to-eat foods

USDA-ARS?s Scientific Manuscript database

Newly emerging nonthermal and advanced thermal processing technologies are now being adopted by the food processing industry for the purpose of providing safe and high quality food products to consumers. Scientists and engineers at USDA’s Eastern Regional Research Center in Wyndmoor, PA are activel...

A bill to authorize the appropriation of funds to the Centers for Disease Control and Prevention for conducting or supporting research on firearms safety or gun violence prevention.

THOMAS, 113th Congress

Sen. Markey, Edward J. [D-MA

2014-05-21

Senate - 05/21/2014 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Management of Library Security. SPEC Kit 247 and SPEC Flyer 247.

ERIC Educational Resources Information Center

Soete, George J., Comp.; Zimmerman, Glen, Comp.

This SPEC (Systems and Procedures Exchange Center) Kit and Flyer reports results of a survey conducted in January 1999 that examined how ARL (Association of Research Libraries) member libraries assure the safety and security of persons, library materials, physical facilities, furnishings, computer equipment, etc. Forty-five of the 122 ARL member…

Young Children Can Be Key to Fire-Safe Families

ERIC Educational Resources Information Center

Kourofsky, Carolyn E.; Cole, Robert E.

2010-01-01

For more than 15 years, preschool programs nationwide have worked with Fireproof Children/Prevention First, an international center for injury prevention research and education, to bring fire safety education to young children and their families. The "play safe! be safe!"[R] curriculum includes lessons that young children can learn and understand,…

Performance measurement evaluation framework and co-benefit / tradeoff analysis for connected and automated vehicles (CAV) applications : a survey : a research report from the National Center for Sustainable Transportation.

DOT National Transportation Integrated Search

2017-09-01

A number of Connected and/or Automated Vehicle (CAV) applications have recently been designed to improve the performance of our transportation system. Safety, mobility and environmental sustainability are three cornerstone performance metrics when ev...

Combat Fluid Resuscitation Interoperable Capability (Capacite Interoperable de Liquides de Reanimation en Situation de Combat)

DTIC Science & Technology

2010-10-01

biological samples from 120 patients (generating > 1 million data points) for the determination of biomarkers. An independent Data Safety and...total of 2,184 patients (853 Shock patients and 1,331 TBI patients). Concurrently, DRDC analyzed over 500 biological samples obtained from 120...Center for Biologics Evaluation and Research and Office of Blood Research and Review. The FDA also reviewed the plan for community notification and

Fire Safety Aspects of Polymeric Materials. Volume 2. Test Methods, Specifications and Standards

DTIC Science & Technology

1979-01-01

San Francisco, California. RAYMOND R. HINDERSINN, Section Manager, Research Center, Hooker Chemi- cal Co., Niagara Falls, New York. WILLIAM C ...Administration, Washington, D. C . DANIEL F. SHEEHAN, DoT, U. S. Coast Guard, Washington, D. C . WILLIAM J. WERNER, Department of Housing and Urban Development...Executive Scientists and Director Advances Research Program Laboratory 3M Company P. 0. Box 33221 St. Paul, MIM 55133 Mr. William D. Manly

16 CFR Figure 10 to Part 1203 - Center of Gravity for Drop Assembly

Code of Federal Regulations, 2012 CFR

2012-01-01

... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Center of Gravity for Drop Assembly 10 Figure 10 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Fig. 10 Figure 10 to Part 1203—Center of Gravity for Drop Assembly ER10MR98.01...

16 CFR Figure 10 to Part 1203 - Center of Gravity for Drop Assembly

Code of Federal Regulations, 2013 CFR

2013-01-01

... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Center of Gravity for Drop Assembly 10 Figure 10 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Fig. 10 Figure 10 to Part 1203—Center of Gravity for Drop Assembly ER10MR98.01...

16 CFR Figure 10 to Part 1203 - Center of Gravity for Drop Assembly

Code of Federal Regulations, 2011 CFR

2011-01-01

... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Center of Gravity for Drop Assembly 10 Figure 10 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Fig. 10 Figure 10 to Part 1203—Center of Gravity for Drop Assembly ER10MR98.01...

16 CFR Figure 10 to Part 1203 - Center of Gravity for Drop Assembly

Code of Federal Regulations, 2014 CFR

2014-01-01

... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Center of Gravity for Drop Assembly 10 Figure 10 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Fig. 10 Figure 10 to Part 1203—Center of Gravity for Drop Assembly ER10MR98.01...

16 CFR Figure 10 to Part 1203 - Center of Gravity for Drop Assembly

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Center of Gravity for Drop Assembly 10 Figure 10 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Fig. 10 Figure 10 to Part 1203—Center of Gravity for Drop Assembly ER10MR98.01...

Research on ignition and flame spread of solid materials in Japan

NASA Technical Reports Server (NTRS)

Ito, Kenichi; Fujita, Osamu

1995-01-01

Fire safety is one of the main concerns for crewed missions such as the space station. Materials used in spacecraft may burn even if metalic. There are severe restrictions on the materials used in spacecraft from the view of fire safety. However, such restrictions or safety standards are usually determined based on experimental results under normal gravity, despite large differences between the phenomena under normal and microgravity. To evaluate the appropriateness of materials for use in space, large amount of microgravity fire-safety combustion data is urgently needed. Solid material combustion under microgravity, such as ignition and flame spread, is a relatively new research field in Japan. As the other reports in this workshop describe, most of microgravity combustion research in Japan is droplet combustion as well as some research on gas phase combustion. Since JAMIC, the Japan Microgravity Center, (which offers 10 seconds microgravity time) opened in 1992, microgravity combustion research is robust, and many drop tests relating to solid combustion (paper combustion, cotton string combustion, metal combustion with Aluminium or Magnesium) have been performed. These tests proved that the 10 seconds of microgravity time at JAMIC is useful for solid combustion research. Some experiments were performed before JAMIC opened. For example, latticed paper was burned under microgravity by using a 50 m drop tower to simulate porous material combustion under microgravity. A 50 m tower provides only 2 seconds microgravity time however, and it was not long enough to investigate the solid combustion phenomena.

Moving Toward Improved Teamwork in Cancer Care: The Role of Psychological Safety in Team Communication.

PubMed

Jain, Anshu K; Fennell, Mary L; Chagpar, Anees B; Connolly, Hannah K; Nembhard, Ingrid M

2016-11-01

Effective communication is a requirement in the teamwork necessary for improved coordination to deliver patient-centered, value-based cancer care. Communication is particularly important when care providers are geographically distributed or work across organizations. We review organizational and teams research on communication to highlight psychological safety as a key determinant of high-quality communication within teams. We first present the concept of psychological safety, findings about its communication effects for teamwork, and factors that affect it. We focus on five factors applicable to cancer care delivery: familiarity, clinical hierarchy-related status differences, geographic dispersion, boundary spanning, and leader behavior. To illustrate how these factors facilitate or hinder psychologically safe communication and teamwork in cancer care, we review the case of a patient as she experiences the treatment-planning process for early-stage breast cancer in a community setting. Our analysis is summarized in a key principle: Teamwork in cancer care requires high-quality communication, which depends on psychological safety for all team members, clinicians and patients alike. We conclude with a discussion of the implications of psychological safety in clinical care and suggestions for future research.

Does Employee Safety Matter for Patients Too? Employee Safety Climate and Patient Safety Culture in Health Care.

PubMed

Mohr, David C; Eaton, Jennifer Lipkowitz; McPhaul, Kathleen M; Hodgson, Michael J

2015-04-22

We examined relationships between employee safety climate and patient safety culture. Because employee safety may be a precondition for the development of patient safety, we hypothesized that employee safety culture would be strongly and positively related to patient safety culture. An employee safety climate survey was administered in 2010 and assessed employees' views and experiences of safety for employees. The patient safety survey administered in 2011 assessed the safety culture for patients. We performed Pearson correlations and multiple regression analysis to examine the relationships between a composite measure of employee safety with subdimensions of patient safety culture. The regression models controlled for size, geographic characteristics, and teaching affiliation. Analyses were conducted at the group level using data from 132 medical centers. Higher employee safety climate composite scores were positively associated with all 9 patient safety culture measures examined. Standardized multivariate regression coefficients ranged from 0.44 to 0.64. Medical facilities where staff have more positive perceptions of health care workplace safety climate tended to have more positive assessments of patient safety culture. This suggests that patient safety culture and employee safety climate could be mutually reinforcing, such that investments and improvements in one domain positively impacts the other. Further research is needed to better understand the nexus between health care employee and patient safety to generalize and act upon findings.

Status of the Space-Rated Lithium-Ion Battery Advanced Development Project in Support of the Exploration Vision

NASA Technical Reports Server (NTRS)

Miller, Thomas

2007-01-01

The NASA Glenn Research Center (GRC), along with the Goddard Space Flight Center (GSFC), Jet Propulsion Laboratory (JPL), Johnson Space Center (JSC), Marshall Space Flight Center (MSFC), and industry partners, is leading a space-rated lithium-ion advanced development battery effort to support the vision for Exploration. This effort addresses the lithium-ion battery portion of the Energy Storage Project under the Exploration Technology Development Program. Key discussions focus on the lithium-ion cell component development activities, a common lithium-ion battery module, test and demonstration of charge/discharge cycle life performance and safety characterization. A review of the space-rated lithium-ion battery project will be presented highlighting the technical accomplishments during the past year.

NASA Dryden's UAS Service Capabilities

NASA Technical Reports Server (NTRS)

Bauer, Jeff

2007-01-01

The vision of NASA s Dryden Flight Research Center is to "fly what others only imagine." Its mission is to advance technology and science through flight. Objectives supporting the mission include performing flight research and technology integration to revolutionize aviation and pioneer aerospace technology, validating space exploration concepts, conducting airborne remote sensing and science missions, and supporting operations of the Space Shuttle and the International Space Station. A significant focus of effort in recent years has been on Unmanned Aircraft Systems (UAS), both in support of the Airborne Science Program and as research vehicles to advance the state of the art in UAS. Additionally, the Center has used its piloted aircraft in support of UAS technology development. In order to facilitate greater access to the UAS expertise that exists at the Center, that expertise has been organized around three major capabilities. The first is access to high-altitude, long-endurance UAS. The second is the establishment of a test range for small UAS. The third is safety case assessment support.

77 FR 35900 - Safety Zone; Gilmerton Bridge Center Span Float-in, Elizabeth River; Norfolk, Portsmouth, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-15

...-AA00 Safety Zone; Gilmerton Bridge Center Span Float-in, Elizabeth River; Norfolk, Portsmouth, and... navigable waters during the Gilmerton Bridge Center Span Float- in and bridge construction of span placement... the existing bascule spans from the Gilmerton Bridge, transport the new center span from the Eastern...

NASA Aviation Safety Program Weather Accident Prevention/weather Information Communications (WINCOMM)

NASA Technical Reports Server (NTRS)

Feinberg, Arthur; Tauss, James; Chomos, Gerald (Technical Monitor)

2002-01-01

Weather is a contributing factor in approximately 25-30 percent of general aviation accidents. The lack of timely, accurate and usable weather information to the general aviation pilot in the cockpit to enhance pilot situational awareness and improve pilot judgment remains a major impediment to improving aviation safety. NASA Glenn Research Center commissioned this 120 day weather datalink market survey to assess the technologies, infrastructure, products, and services of commercial avionics systems being marketed to the general aviation community to address these longstanding safety concerns. A market survey of companies providing or proposing to provide graphical weather information to the general aviation cockpit was conducted. Fifteen commercial companies were surveyed. These systems are characterized and evaluated in this report by availability, end-user pricing/cost, system constraints/limits and technical specifications. An analysis of market survey results and an evaluation of product offerings were made. In addition, recommendations to NASA for additional research and technology development investment have been made as a result of this survey to accelerate deployment of cockpit weather information systems for enhancing aviation safety.

Implementation of safety signage to ease transportation system in disaster prone area

NASA Astrophysics Data System (ADS)

Vikneswaran, M.; Raffiee, Rabiatul Adawiyah Ahmad; Yusof, Mohammed Alias; Yahya, Muhamad Azani; Subramaniam, S. Ananthan; Loong, Wong Wai; Othman, Maidiana; Galerial, Jessica

2018-02-01

The research is conducted to study the exact need of the signage at disaster prone area. The smart signage is needed to increase the safety, reduce the search and rescue time and finally will ease the help to arrive at the relieve center in any condition at any time without interruption. Signage implementation for disaster relief centers is still a foreign matter in Malaysia. The level of preparedness to the natural disaster mainly flood among our citizens is inadequate. Here the signage which usually used as a tool to help and protect the health and safety of the road users, employees and work place visitors. For many years, the signage has played its part miraculously to provide vivid information to the users in whatever condition. The signage also could be used as an indicator or information provider for the natural disaster victims to move to a safer place on time. Sometimes, the victims would not have sufficient time to safe themselves due to lack of information and time. Thus, it can be concluded that the signage at disaster prone area is vital.

The Vaccine Safety Datalink: immunization research in health maintenance organizations in the USA.

PubMed Central

Chen, R. T.; DeStefano, F.; Davis, R. L.; Jackson, L. A.; Thompson, R. S.; Mullooly, J. P.; Black, S. B.; Shinefield, H. R.; Vadheim, C. M.; Ward, J. I.; Marcy, S. M.

2000-01-01

The Vaccine Safety Datalink is a collaborative project involving the National Immunization Program of the Centers for Disease Control and Prevention and several large health maintenance organizations in the USA. The project began in 1990 with the primary purpose of rigorously evaluating concerns about the safety of vaccines. Computerized data on vaccination, medical outcome (e.g. outpatient visits, emergency room visits, hospitalizations, and deaths) and covariates (e.g. birth certificates, census data) are prospectively collected and linked under joint protocol at multiple health maintenance organizations for analysis. Approximately 6 million persons (2% of the population of the USA) are now members of health maintenance organizations participating in the Vaccine Safety Datalink, which has proved to be a valuable resource providing important information on a number of vaccine safety issues. The databases and infrastructure created for the Vaccine Safety Datalink have also provided opportunities to address vaccination coverage, cost-effectiveness and other matters connected with immunization as well as matters outside this field. PMID:10743283

Graduate Research Assistant Program for Professional Development at Oak Ridge National Laboratory (ORNL) Global Nuclear Security Technology Division (GNSTD)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eipeldauer, Mary D; Shelander Jr, Bruce R

2012-01-01

The southeast is a highly suitable environment for establishing a series of nuclear safety, security and safeguards 'professional development' courses. Oak Ridge National Laboratory (ORNL) provides expertise in the research component of these subjects while the Y-12 Nuclear Security Complex handles safeguards/security and safety applications. Several universities (i.e., University of Tennessee, Knoxville (UTK), North Carolina State University, University of Michigan, and Georgia Technology Institute) in the region, which offer nuclear engineering and public policy administration programs, and the Howard Baker Center for Public Policy make this an ideal environment for learning. More recently, the Institute for Nuclear Security (INS) wasmore » established between ORNL, Y-12, UTK and Oak Ridge Associate Universities (ORAU), with a focus on five principal areas. These areas include policy, law, and diplomacy; education and training; science and technology; operational and intelligence capability building; and real-world missions and applications. This is a new approach that includes professional development within the graduate research assistant program addressing global needs in nuclear security, safety and safeguards.« less

White Paper on studying the safety of the childhood immunization schedule in the Vaccine Safety Datalink.

PubMed

Glanz, Jason M; Newcomer, Sophia R; Jackson, Michael L; Omer, Saad B; Bednarczyk, Robert A; Shoup, Jo Ann; DeStefano, Frank; Daley, Matthew F

2016-02-15

While the large majority of parents in the U.S. vaccinate their children according to the recommended immunization schedule, some parents have refused or delayed vaccinating, often citing safety concerns. In response to public concern, the U.S. Institute of Medicine (IOM) evaluated existing research regarding the safety of the recommended immunization schedule. The IOM concluded that although available evidence strongly supported the safety of the currently recommended schedule as a whole, additional observational research was warranted to compare health outcomes between fully vaccinated children and those on a delayed or alternative schedule. In addition, the IOM identified the Vaccine Safety Datalink (VSD) as an important resource for conducting this research. Guided by the IOM findings, the Centers for Disease Control and Prevention (CDC) commissioned a White Paper to assess how the VSD could be used to study the safety of the childhood immunization schedule. Guided by subject matter expert engagement, the resulting White Paper outlines a 4 stage approach for identifying exposure groups of undervaccinated children, presents a list of health outcomes of highest priority to examine in this context, and describes various study designs and statistical methods that could be used to analyze the safety of the schedule. While it appears feasible to study the safety of the recommended immunization schedule in settings such as the VSD, these studies will be inherently complex, and as with all observational studies, will need to carefully address issues of confounding and bias. In light of these considerations, decisions about conducting studies of the safety of the schedule will also need to assess epidemiological evidence of potential adverse events that could be related to the schedule, the biological plausibility of an association between an adverse event and the schedule, and public concern about the safety of the schedule. Copyright © 2015 Elsevier Ltd. All rights reserved.

Waste Processing Research and Technology Development at NASA Ames Research Center

NASA Technical Reports Server (NTRS)

Fisher, John; Kliss, Mark

2004-01-01

The current "store and return" approach for handling waste products generated during low Earth orbit missions will not meet the requirements for future human missions identified in NASA s new Exploration vision. The objective is to develop appropriate reliable waste management systems that minimize maintenance and crew time, while maintaining crew health and safety, as well as providing protection of planetary surfaces. Solid waste management requirements for these missions include waste volume reduction, stabilization and storage, water recovery, and ultimately recovery of carbon dioxide, nutrients and other resources from a fully regenerative food production life support system. This paper identifies the key drivers for waste management technology development within NASA, and provides a roadmap for the developmental sequence and progression of technologies. Recent results of research and technology development activities at NASA Ames Research Center on candidate waste management technologies with emphasis on compaction, lyophilization, and incineration are discussed.

Concurrent engineering research center

NASA Technical Reports Server (NTRS)

Callahan, John R.

1995-01-01

The projects undertaken by The Concurrent Engineering Research Center (CERC) at West Virginia University are reported and summarized. CERC's participation in the Department of Defense's Defense Advanced Research Project relating to technology needed to improve the product development process is described, particularly in the area of advanced weapon systems. The efforts committed to improving collaboration among the diverse and distributed health care providers are reported, along with the research activities for NASA in Independent Software Verification and Validation. CERC also takes part in the electronic respirator certification initiated by The National Institute for Occupational Safety and Health, as well as in the efforts to find a solution to the problem of producing environment-friendly end-products for product developers worldwide. The 3M Fiber Metal Matrix Composite Model Factory Program is discussed. CERC technologies, facilities,and personnel-related issues are described, along with its library and technical services and recent publications.

The NASA Dryden Flight Research Center Unmanned Aircraft System Service Capabilities

NASA Technical Reports Server (NTRS)

Bauer, Jeff

2007-01-01

Over 60 years of Unmanned Aircraft System (UAS) expertise at the NASA Dryden Flight Research Center are being leveraged to provide capability and expertise to the international UAS community. The DFRC brings together technical experts, UAS, and an operational environment to provide government and industry a broad capability to conduct research, perform operations, and mature systems, sensors, and regulation. The cornerstone of this effort is the acquisition of both a Global Hawk (Northrop Grumman Corporation, Los Angeles, California) and Predator B (General Atomics Aeronautical Systems, Inc., San Diego, California) unmanned aircraft system (UAS). In addition, a test range for small UAS will allow developers to conduct research and development flights without the need to obtain approval from civil authorities. Finally, experts are available to government and industry to provide safety assessments in support of operations in civil airspace. These services will allow developers to utilize limited resources to their maximum capability in a highly competitive environment.

Advanced spacecraft fire safety: Proposed projects and program plan

NASA Technical Reports Server (NTRS)

Youngblood, Wallace W.; Vedha-Nayagam, M.

1989-01-01

A detailed review identifies spacecraft fire safety issues and the efforts for their resolution, particularly for the threats posed by the increased on-orbit duration, size, and complexity of the Space Station Freedom. Suggestions provided by a survey of Wyle consultants and outside fire safety experts were combined into 30 research and engineering projects. The projects were then prioritized with respect to urgency to meet Freedom design goals, status of enabling technology, cost, and so on, to yield 14 highest priority projects, described in terms of background, work breakdown structure, and schedule. These highest priority projects can be grouped into the thematic areas of fire detection, fire extinguishment, risk assessment, toxicology and human effects, and ground based testing. Recommendations for overall program management stress the need for NASA Headquarters and field center coordination, with information exchange through spacecraft fire safety oversight committees.

A Study of the System Safety Concept as it Relates to the New Walter Reed Army Medical Center, Washington, DC.

DTIC Science & Technology

1978-03-31

established the safety level of the% * originally designed facility and the extent of current safety * modifications. The objectives evaluated the...Program could identify many safety hazards thus leading to design improvements. The study provided several recommendations to formalize the Systems Safety... design , construction, and proposed systems management of the new Walter Reed Army Medical Center (WRAMC), Washington, D.C., was conducted during the

21 CFR 172.809 - Curdlan.

Code of Federal Regulations, 2013 CFR

2013-04-01

... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN... available from the Office of Food Additive Safety (HFS-200), Center for Food Safety and Applied Nutrition... examined at the Center for Food Safety and Applied Nutrition's Library, Food and Drug Administration, 5100...

Demonstration of a Safety Analysis on a Complex System

NASA Technical Reports Server (NTRS)

Leveson, Nancy; Alfaro, Liliana; Alvarado, Christine; Brown, Molly; Hunt, Earl B.; Jaffe, Matt; Joslyn, Susan; Pinnell, Denise; Reese, Jon; Samarziya, Jeffrey;

Southwest Border Food Safety and Defense Center: Creative Ideas for Promoting Food Safety and Food Protection

ERIC Educational Resources Information Center

Koukel, Sonja

2015-01-01

Foodborne illness has a significant impact on public health and consumer confidence in the U.S. The Southwest Border Food Safety and Defense Center was established to provide educational programs, trainings, and workshops to address the health and well-being of consumers as it relates to food safety and food protection. A partnership between New…

Strengthening National, Homeland, and Economic Security. Networking and Information Technology Research and Development Supplement to the President’s FY 2003 Budget

DTIC Science & Technology

2002-07-01

Knowledge From Data .................................................. 25 HIGH-CONFIDENCE SOFTWARE AND SYSTEMS Reliability, Security, and Safety for...NOAA’s Cessna Citation flew over the 16-acre World Trade Center site, scanning with an Optech ALSM unit. The system recorded data points from 33,000...provide the data storage and compute power for intelligence analysis, high-performance national defense systems , and critical scientific research • Large

Research of medical gases in Poland

PubMed Central

2013-01-01

Research of medical gases is well established in Poland and has been marked with the foundation of several professional societies. Numerous academic centers including those dealing with hyperbaric and diving medicine conduct studies of medical gases, in vast majority supported with intramural funds. In general, Polish research of medical gases is very much clinical in nature, covering new applications and safety of medical gases in medicine; on the other hand there are several academic centers pursuing preclinical studies, and elaborating basic theories of gas physiology and mathematical modeling of gas exchange. What dominates is research dealing with oxygen and ozone as well as studies of anesthetic gases and their applications. Finally, several research directions involving noble gas, hydrogen and hydrogen sulfide for cell protection, only begin to gain recognition of basic scientists and clinicians. However, further developments require more monetary spending on research and clinical testing as well as formation of new collective bodies for coordinating efforts in this matter. PMID:23916016

KENNEDY SPACE CENTER, FLA. - Astronaut Barry E. Wilmore (left) and Center Director Jim Kennedy pose for a photo after Wilmore presented Kennedy with a special award for Spaceport Super Safety and Health Day.

NASA Image and Video Library

2003-10-15

KENNEDY SPACE CENTER, FLA. - Astronaut Barry E. Wilmore (left) and Center Director Jim Kennedy pose for a photo after Wilmore presented Kennedy with a special award for Spaceport Super Safety and Health Day.

21 CFR 100.2 - State enforcement of Federal regulations.

Code of Federal Regulations, 2010 CFR

2010-04-01

...-605), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch... Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch Pkwy., College Park, MD... notification was received by FDA, Center for Food Safety and Applied Nutrition, Division of Enforcement (HFS...

21 CFR 100.2 - State enforcement of Federal regulations.

Code of Federal Regulations, 2011 CFR

2011-04-01

...-605), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch... Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch Pkwy., College Park, MD... notification was received by FDA, Center for Food Safety and Applied Nutrition, Division of Enforcement (HFS...

21 CFR 100.2 - State enforcement of Federal regulations.

Code of Federal Regulations, 2012 CFR

2012-04-01

...-605), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch... Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch Pkwy., College Park, MD... notification was received by FDA, Center for Food Safety and Applied Nutrition, Division of Enforcement (HFS...

21 CFR 100.2 - State enforcement of Federal regulations.

Code of Federal Regulations, 2014 CFR

2014-04-01

...-605), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch... Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch Pkwy., College Park, MD... notification was received by FDA, Center for Food Safety and Applied Nutrition, Division of Enforcement (HFS...

21 CFR 100.2 - State enforcement of Federal regulations.

Code of Federal Regulations, 2013 CFR

2013-04-01

...-605), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch... Safety and Applied Nutrition, Food and Drug Administration, 5100 Paint Branch Pkwy., College Park, MD... notification was received by FDA, Center for Food Safety and Applied Nutrition, Division of Enforcement (HFS...

MOD-OA 200 kW wind turbine generator engineeringing

NASA Technical Reports Server (NTRS)

Andersen, T. S.; Bodenschatz, C. A.; Eggers, A. G.; Hughes, P. S.; Lampe, R. F.

1980-01-01

Engineering drawings and the detailed mechanical and electrical design of a horizontal-axis wind turbine designed for DOE at the NASA Lewis Research Center and installed in Clayton, New Mexico are discussed. The drawings show the hub, pitch change mechanism, drive train, nacelle equipment, yaw drive system, tower, foundation, electrical power systems, and the control and safety systems.

76 FR 38666 - Food and Drug Administration (FDA) and Marine Environmental Sciences Consortium/Dauphin Island...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-01

... actively involved in both basic and applied research in coastal waters of the northern Gulf of Mexico. The... between the Center for Food Safety and Applied Nutrition (CFSAN) and the Marine Environmental Sciences Consortium/Dauphin Island Sea Lab (DISL). The goal of the DISL is marine science education, basic and applied...

78 FR 36192 - National Institute for Occupational Safety and Health (NIOSH) Traumatic Injury Research and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-17

... comments should be formatted as Microsoft Word. Please make reference to CDC-2013-0009 and Docket Number... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention (CDC) [CDC-2013....regulations.gov and enter CDC-2013-0009 in the search field and click ``Search.'' Public comment period...

Space Human Factors: Research to Application

NASA Technical Reports Server (NTRS)

Woolford, Barbara

2008-01-01

Human Factors has been instrumental in preventing potential on-orbit hazards and increasing overall crew safety. Poor performance & operational learning curves on-orbit are mitigated. Human-centered design is applied to optimize design and minimize potentially hazardous conditions, especially with larger crew sizes and habitat constraints. Lunar and Mars requirements and design developments are enhanced, based on ISS Lessons Learned.

Risk management systems for health care and safety development on transplantation: a review and a proposal.

PubMed

Pretagostini, R; Gabbrielli, F; Fiaschetti, P; Oliveti, A; Cenci, S; Peritore, D; Stabile, D

2010-05-01

Starting from the report on medical errors published in 1999 by the US Institute of Medicine, a number of different approaches to risk management have been developed for maximum risk reduction in health care activities. The health care authorities in many countries have focused attention on patient safety, employing action research programs that are based on quite different principles. We performed a systematic Medline research of the literature since 1999. The following key words were used, also combining boolean operators and medical subheading terms: "adverse event," "risk management," "error," and "governance." Studies published in the last 5 years were particularly classified in various groups: risk management in health care systems; safety in specific hospital activities; and health care institutions' official documents. Methods of action researches have been analysed and their characteristics compared. Their suitability for safety development in donation, retrieval, and transplantation processes were discussed in the reality of the Italian transplant network. Some action researches and studies were dedicated to entire national healthcare systems, whereas others focused on specific risks. Many research programs have undergone critical review in the literature. Retrospective analysis has centered on so-called sentinel events to particularly analyze only a minor portion of the organizational phenomena, which can be the origin of an adverse event, an incident, or an error. Sentinel events give useful information if they are studied in highly engineered and standardized organizations like laboratories or tissue establishments, but they show several limits in the analysis of organ donation, retrieval, and transplantation processes, which are characterized by prevailing human factors, with high intrinsic risk and variability. Thus, they are poorly effective to deliver sure elements to base safety management improvement programs, especially regarding multidisciplinary systems with high complexity. In organ transplantation, the possibility to increase safety seems greater using proactive research, mainly centred on organizational processes together with retrospective analyses but not limited to sentinel event reports. Copyright (c) 2010. Published by Elsevier Inc.

Medicare Payment Penalties and Safety Net Hospital Profitability: Minimal Impact on These Vulnerable Hospitals.

PubMed

Bazzoli, Gloria J; Thompson, Michael P; Waters, Teresa M

2018-02-08

To examine relationships between penalties assessed by Medicare's Hospital Readmission Reduction Program and Value-Based Purchasing Program and hospital financial condition. Centers for Medicare and Medicaid Services, American Hospital Association, and Area Health Resource File data for 4,824 hospital-year observations. Bivariate and multivariate analysis of pooled cross-sectional data. Safety net hospitals have significantly higher HRRP/VBP penalties, but, unlike nonsafety net hospitals, increases in their penalty rate did not significantly affect their total margins. Safety net hospitals appear to rely on nonpatient care revenues to offset higher penalties for the years studied. While reassuring, these funding streams are volatile and may not be able to compensate for cumulative losses over time. © Health Research and Educational Trust.

Socio-Technical Systems Analysis in Health Care: A Research Agenda

PubMed Central

Bass, Ellen; Bellandi, Tommaso; Gurses, Ayse; Hallbeck, Susan; Mollo, Vanina

2012-01-01

Given the complexity of health care and the ‘people’ nature of healthcare work and delivery, STSA (Sociotechnical Systems Analysis) research is needed to address the numerous quality of care problems observed across the world. This paper describes open STSA research areas, including workload management, physical, cognitive and macroergonomic issues of medical devices and health information technologies, STSA in transitions of care, STSA of patient-centered care, risk management and patient safety management, resilience, and feedback loops between event detection, reporting and analysis and system redesign. PMID:22611480

KSC-03pd0105

NASA Image and Video Library

2003-01-16

KENNEDY SPACE CENTER, FLA. - STS-107 Payload Commander Michael Anderson is happy to being suiting up for launch on mission STS-107. The mission is devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST.

Illuminating Cell Biology

NASA Technical Reports Server (NTRS)

2002-01-01

NASA's Ames Research Center awarded Ciencia, Inc., a Small Business Innovation Research contract to develop the Cell Fluorescence Analysis System (CFAS) to address the size, mass, and power constraints of using fluorescence spectroscopy in the International Space Station's Life Science Research Facility. The system will play an important role in studying biological specimen's long-term adaptation to microgravity. Commercial applications for the technology include diverse markets such as food safety, in situ environmental monitoring, online process analysis, genomics and DNA chips, and non-invasive diagnostics. Ciencia has already sold the system to the private sector for biosensor applications.

Nuclear Photonics

NASA Astrophysics Data System (ADS)

Nedorezov, V. G.; Savel'ev-Trofimov, A. B.

2017-12-01

A review of works performed at the Institute for Nuclear Research of the Russian Academy of Sciences and at the International Laser Center of the Moscow State University in the context of the new research area called "nuclear photonics" is presented. Nuclear photonics is based on creation of the new-generation gamma-ray sources which make it possible to solve a number of fundamental and applied problems, including research of low-energy photonuclear reactions, namely, investigation of collective excitations of nuclei near the threshold (pygmy resonances); nuclear safety assurance; production of low-energy positron beams; and phase-contrast X-ray imaging.

Planning the Safety of Atrial Fibrillation Ablation Registry Initiative (SAFARI) as a Collaborative Pan-Stakeholder Critical Path Registry Model: a Cardiac Safety Research Consortium "Incubator" Think Tank.

PubMed

Al-Khatib, Sana M; Calkins, Hugh; Eloff, Benjamin C; Packer, Douglas L; Ellenbogen, Kenneth A; Hammill, Stephen C; Natale, Andrea; Page, Richard L; Prystowsky, Eric; Jackman, Warren M; Stevenson, William G; Waldo, Albert L; Wilber, David; Kowey, Peter; Yaross, Marcia S; Mark, Daniel B; Reiffel, James; Finkle, John K; Marinac-Dabic, Danica; Pinnow, Ellen; Sager, Phillip; Sedrakyan, Art; Canos, Daniel; Gross, Thomas; Berliner, Elise; Krucoff, Mitchell W

2010-01-01

Atrial fibrillation (AF) is a major public health problem in the United States that is associated with increased mortality and morbidity. Of the therapeutic modalities available to treat AF, the use of percutaneous catheter ablation of AF is expanding rapidly. Randomized clinical trials examining the efficacy and safety of AF ablation are currently underway; however, such trials can only partially determine the safety and durability of the effect of the procedure in routine clinical practice, in more complex patients, and over a broader range of techniques and operator experience. These limitations of randomized trials of AF ablation, particularly with regard to safety issues, could be addressed using a synergistically structured national registry, which is the intention of the SAFARI. To facilitate discussions about objectives, challenges, and steps for such a registry, the Cardiac Safety Research Consortium and the Duke Clinical Research Institute, Durham, NC, in collaboration with the US Food and Drug Administration, the American College of Cardiology, and the Heart Rhythm Society, organized a Think Tank meeting of experts in the field. Other participants included the National Heart, Lung and Blood Institute, the Centers for Medicare and Medicaid Services, the Agency for Healthcare Research and Quality, the Society of Thoracic Surgeons, the AdvaMed AF working group, and additional industry representatives. The meeting took place on April 27 to 28, 2009, at the US Food and Drug Administration headquarters in Silver Spring, MD. This article summarizes the issues and directions presented and discussed at the meeting. Copyright 2010 Mosby, Inc. All rights reserved.

Probing Aircraft Flight Test Hazard Mitigation for the Alternative Fuel Effects on Contrails and Cruise Emissions (ACCESS) Research Team . Volume 2; Appendices

NASA Technical Reports Server (NTRS)

Kelly, Michael J.

2013-01-01

The Alternative Fuel Effects on Contrails and Cruise Emissions (ACCESS) Project Integration Manager requested in July 2012 that the NASA Engineering and Safety Center (NESC) form a team to independently assess aircraft structural failure hazards associated with the ACCESS experiment and to identify potential flight test hazard mitigations to ensure flight safety. The ACCESS Project Integration Manager subsequently requested that the assessment scope be focused predominantly on structural failure risks to the aircraft empennage (horizontal and vertical tail). This report contains the Appendices to Volume I.

Food and Drug Administration workshop on indirect mechanisms of carcinogenesis.

PubMed

Poirier, L A

1996-01-01

A workshop sponsored by the Food and Drug Administration (FDA) was held on March 4-5, 1996, at the Lister Hill Auditorium of the National Institutes of Health (NIH) Campus in Bethesda, Maryland. The workshop considered both the scientific aspects and the regulatory implications of indirect-acting carcinogens. A wide variety of agents and of prospective mechanisms was discussed. The organizing committee for the workshop consisted of Drs. James Farrelly and Joseph DeGeorge of the Center for Drug Evaluation and Research (CDER), Ronald J. Lorentzen and Sidney Green of the Center for Food Safety and Applied Nutrition (CFSAN), Martin D. Green of the Center for Biologics, Evaluation and Research (CBER), C. Darnell Jackson and Lionel A. Poirier of the National Center for Toxicological Research (NCTR). Rosalie K. Elespuru of the Center for Devices and Radiological Health (CDRH), and David G. Longfellow of the National Cancer Institute (NCI). Following an introduction by Dr. Poirier, who provided a description of indirect carcinogens, the major talks were grouped into three formal sessions: indirect-acting compounds and agents of FDA interest, biological and biochemical endpoints commonly seen with indirect agents, and specific problems associated with the indirect-acting compounds. A panel discussion followed and the concluding remarks were made by Dr. Bernard A. Schwetz, Associate Commissioner for Science, FDA.

Personal Aircraft Point to the Future of Transportation

NASA Technical Reports Server (NTRS)

2010-01-01

NASA's Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs, as well as a number of Agency innovations, have helped Duluth, Minnesota-based Cirrus Design Corporation become one of the world's leading manufacturers of general aviation aircraft. SBIRs with Langley Research Center provided the company with cost-effective composite airframe manufacturing methods, while crashworthiness testing at the Center increased the safety of its airplanes. Other NASA-derived technologies on Cirrus SR20 and SR22 aircraft include synthetic vision systems that help pilots navigate and full-plane parachutes that have saved the lives of more than 30 Cirrus pilots and passengers to date. Today, the SR22 is the world's top-selling Federal Aviation Administration (FAA)-certified single-engine airplane.

Restoration of the Hypersonic Tunnel Facility at NASA Glenn Research Center, Plum Brook Station

NASA Technical Reports Server (NTRS)

Woodling, Mark A.

2000-01-01

The NASA Glenn Research Center's Hypersonic Tunnel Facility (HTF), located at the Plum Brook Station in Sandusky, Ohio, is a non-vitiated, free-jet facility, capable of testing large-scale propulsion systems at Mach Numbers from 5 to 7. As a result of a component failure in September of 1996, a restoration project was initiated in mid- 1997 to repair the damage to the facility. Following the 2-1/2 year effort, the HTF has been returned to an operational condition. Significant repairs and operational improvements have been implemented in order to ensure facility reliability and personnel safety. As of January 2000, this unique, state-of-the-art facility was ready for integrated systems testing.

21 CFR 172.712 - 1,3-Butylene glycol.

Code of Federal Regulations, 2013 CFR

2013-04-01

... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR... Additive Safety (HFS-200), Center for Food Safety and Applied Nutrition, 5100 Paint Branch Pkwy., College Park, MD 20740, 240-402-1200, or may be examined at the Center for Food Safety and Applied Nutrition's...

Information Services at the Nuclear Safety Analysis Center.

ERIC Educational Resources Information Center

Simard, Ronald

This paper describes the operations of the Nuclear Safety Analysis Center. Established soon after an accident at the Three Mile Island nuclear power plant near Harrisburg, Pennsylvania, its efforts were initially directed towards a detailed analysis of the accident. Continuing functions include: (1) the analysis of generic nuclear safety issues,…

Stennis Space Center observes 2009 Safety and Health Day

NASA Technical Reports Server (NTRS)

2009-01-01

Sue Smith, a medical clinic employee at NASA's John C. Stennis Space Center, takes the temperature of colleague Karen Badon during 2009 Safety and Health Day activities Oct. 22. Safety Day activities included speakers, informational sessions and a number of displays on safety and health issues. Astronaut Dominic Gorie also visited the south Mississippi rocket engine testing facility during the day to address employees and present several Silver Snoopy awards for outstanding contributions to flight safety and mission success. The activities were part of an ongoing safety and health emphasis at Stennis.

Modeling to Mars: a NASA Model Based Systems Engineering Pathfinder Effort

NASA Technical Reports Server (NTRS)

Phojanamongkolkij, Nipa; Lee, Kristopher A.; Miller, Scott T.; Vorndran, Kenneth A.; Vaden, Karl R.; Ross, Eric P.; Powell, Bobby C.; Moses, Robert W.

2017-01-01

The NASA Engineering Safety Center (NESC) Systems Engineering (SE) Technical Discipline Team (TDT) initiated the Model Based Systems Engineering (MBSE) Pathfinder effort in FY16. The goals and objectives of the MBSE Pathfinder include developing and advancing MBSE capability across NASA, applying MBSE to real NASA issues, and capturing issues and opportunities surrounding MBSE. The Pathfinder effort consisted of four teams, with each team addressing a particular focus area. This paper focuses on Pathfinder team 1 with the focus area of architectures and mission campaigns. These efforts covered the timeframe of February 2016 through September 2016. The team was comprised of eight team members from seven NASA Centers (Glenn Research Center, Langley Research Center, Ames Research Center, Goddard Space Flight Center IV&V Facility, Johnson Space Center, Marshall Space Flight Center, and Stennis Space Center). Collectively, the team had varying levels of knowledge, skills and expertise in systems engineering and MBSE. The team applied their existing and newly acquired system modeling knowledge and expertise to develop modeling products for a campaign (Program) of crew and cargo missions (Projects) to establish a human presence on Mars utilizing In-Situ Resource Utilization (ISRU). Pathfinder team 1 developed a subset of modeling products that are required for a Program System Requirement Review (SRR)/System Design Review (SDR) and Project Mission Concept Review (MCR)/SRR as defined in NASA Procedural Requirements. Additionally, Team 1 was able to perform and demonstrate some trades and constraint analyses. At the end of these efforts, over twenty lessons learned and recommended next steps have been identified.

Person-Centered Care: A Definition and Essential Elements.

PubMed

2016-01-01

Improving healthcare safety, quality, and coordination, as well as quality of life, are important aims of caring for older adults with multiple chronic conditions and/or functional limitations. Person-centered care is an approach to meeting these aims, but there are no standardized, agreed-upon parameters for delivering such care. The SCAN Foundation charged a team from the American Geriatrics Society (AGS) in collaboration with a research and clinical team from the Keck School of Medicine of the University of Southern California to provide the evidence base to support a definition of person-centered care and its essential elements. An interprofessional panel of experts in person-centered care principles and practices that the AGS convened developed this statement. © 2015, Copyright the Authors Journal compilation © 2015, The American Geriatrics Society.

Safety assessment characteristics of pedestrian legform impactors in vehicle-front impact tests.

PubMed

Matsui, Yasuhiro

2014-12-01

This study investigated the characteristics of safety assessment results of front-area vehicle impact tests carried out using the Transport Research Laboratory (TRL) legform impactor and a flexible legform impactor (FLEX legform impactor). Different types of vehicles (sedan, sport utility vehicle, high-roof K-car, and light cargo van) were examined. The impact locations in the study were the center of the bumper and an extremely stiff structure of the bumper (i.e., in front of the side member) of each tested vehicle. The measured injury criteria were normalized by injury assessment reference values of each legform impactor. The test results for center and side-member impacts indicated that there were no significant differences in ligament injury assessments derived from the normalized knee ligament injury measures between the TRL legform impactor and the FLEX legform impactor. Evaluations made using the TRL legform impactor and the FLEX legform impactor are thus similar in the vehicle safety investigation for knee ligament injury. Vehicle-center impact test results revealed that the tibia fracture assessments derived from the normalized tibia fracture measures did not significantly differ between the TRL legform impactor and the FLEX legform impactor. However, for an impact against an extremely stiff structure, there was a difference in the tibia fracture assessment between the FLEX legform impactor and the TRL legform impactor owing to their different sensor types. Copyright © 2014 Elsevier Ltd. All rights reserved.

76 FR 40733 - National Institute for Occupational Safety and Health, (NIOSH), World Trade Center Health Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-11

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention National Institute for Occupational Safety and Health, (NIOSH), World Trade Center Health Program Science/Technical Advisory Committee (WTCHP-STAC) Correction: This notice was published in the Federal Register on June 23...

21 CFR 189.5 - Prohibited cattle materials.

Code of Federal Regulations, 2014 CFR

2014-04-01

... to be not adulterated. (3) Mechanically Separated (MS)(Beef) means a meat food product that is finely... Center for Food Safety and Applied Nutrition's Library, 5100 Paint Branch Pkwy., College Park, MD 20740..., Office of the Center Director, Center for Food Safety and Applied Nutrition, Food and Drug Administration...

21 CFR 189.5 - Prohibited cattle materials.

Code of Federal Regulations, 2013 CFR

2013-04-01

... passed, it was found to be not adulterated. (3) Mechanically Separated (MS)(Beef) means a meat food... examined at the Center for Food Safety and Applied Nutrition's Library, 5100 Paint Branch Pkwy., College..., Office of the Center Director, Center for Food Safety and Applied Nutrition, Food and Drug Administration...

21 CFR 189.5 - Prohibited cattle materials.

Code of Federal Regulations, 2011 CFR

2011-04-01

... passed, it was found to be not adulterated. (3) Mechanically Separated (MS)(Beef) means a meat food... examined at the Center for Food Safety and Applied Nutrition's Library, 5100 Paint Branch Pkwy., College..., Office of the Center Director, Center for Food Safety and Applied Nutrition, Food and Drug Administration...

21 CFR 189.5 - Prohibited cattle materials.

Code of Federal Regulations, 2012 CFR

2012-04-01

... passed, it was found to be not adulterated. (3) Mechanically Separated (MS)(Beef) means a meat food... examined at the Center for Food Safety and Applied Nutrition's Library, 5100 Paint Branch Pkwy., College..., Office of the Center Director, Center for Food Safety and Applied Nutrition, Food and Drug Administration...

76 FR 46299 - NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings 2012: Proposed...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-02

... National Institute for Occupational Safety and Health (NIOSH) of the Centers for Disease Control and..., Director, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [Docket Number...

Statement on National WorkLife Priorities

PubMed Central

Cherniack, Martin; Henning, Rob; Merchant, James A.; Punnett, Laura; Sorensen, Glorian R.; Wagner, Gregory

2018-01-01

The National Institute for Occupational Safety and Health (NIOSH) WorkLife Initiative (WLI) [http://www.cdc.gov/niosh/worklife] seeks to promote workplace programs, policies, and practices that result in healthier, more productive employees through a focus simultaneously on disease prevention, health promotion, and accommodations to age, family, and life stage. The Initiative incorporates the Institute’s foundational commitment to workplaces free of recognized hazards into broader consideration of the factors that affect worker health and wellbeing. Workplace hazards, such as physical demands, chemical exposures, and work organization, often interact with non-work factors such as family demands and health behaviors to increase health and safety risks. New workplace interventions being tested by the first three NIOSH WLI Centers of WorkLife Excellence are exploring innovative models for employee health programs to reduce the human, social, and economic costs of compromised health and quality of life. Many parties in industry, labor, and government share the goals of improving employee health while controlling health care costs. NIOSH convened a workshop in 2008 with representatives of the three Centers of Excellence to develop a comprehensive, long-range strategy for advancing the WorkLife Initiative. The recommendations below fall into three areas: practice, research, and policy. Responding to these recommendations would permit the WorkLife Center system to establish a new infrastructure for workplace prevention programs by compiling and disseminating the innovative practices being developed and tested at the Centers, and elsewhere. The WLI would also extend the customary scope of NIOSH by engaging with multiple NIH Institutes that are already generating research-to-practice programs involving the working-age population, in areas such as chronic disease prevention and management. Research to Practice (r2p) is a concept focused on the translation of research findings, technologies, and information into evidence-based prevention practices and products that are adopted in the workplace or other “real-world” settings. NIOSH’s goal is to overcome the translational issues that now prevent state-of-the-art occupational health, health promotion, and chronic disease research findings from benefiting working age populations immediately, regardless of workplace size, work sector, or region of the country. PMID:20949545

Statement on national worklife priorities.

PubMed

Cherniack, Martin; Henning, Rob; Merchant, James A; Punnett, Laura; Sorensen, Glorian R; Wagner, Gregory

2011-01-01

The National Institute for Occupational Safety and Health (NIOSH) WorkLife Initiative (WLI) [http://www.cdc.gov/niosh/worklife] seeks to promote workplace programs, policies, and practices that result in healthier, more productive employees through a focus simultaneously on disease prevention, health promotion, and accommodations to age, family, and life stage. The Initiative incorporates the Institute's foundational commitment to workplaces free of recognized hazards into broader consideration of the factors that affect worker health and wellbeing. Workplace hazards, such as physical demands, chemical exposures, and work organization, often interact with non-work factors such as family demands and health behaviors to increase health and safety risks. New workplace interventions being tested by the first three NIOSH WLI Centers of WorkLife Excellence are exploring innovative models for employee health programs to reduce the human, social, and economic costs of compromised health and quality of life. Many parties in industry, labor, and government share the goals of improving employee health while controlling health care costs. NIOSH convened a workshop in 2008 with representatives of the three Centers of Excellence to develop a comprehensive, long-range strategy for advancing the WorkLife Initiative. The recommendations below fall into three areas: practice, research, and policy. Responding to these recommendations would permit the WorkLife Center system to establish a new infrastructure for workplace prevention programs by compiling and disseminating the innovative practices being developed and tested at the Centers, and elsewhere. The WLI would also extend the customary scope of NIOSH by engaging with multiple NIH Institutes that are already generating research-to-practice programs involving the working-age population, in areas such as chronic disease prevention and management. Research to Practice (r2p) is a concept focused on the translation of research findings, technologies, and information into evidence-based prevention practices and products that are adopted in the workplace or other "real-world" settings. NIOSH's goal is to overcome the translational issues that now prevent state-of-the-art occupational health, health promotion, and chronic disease research findings from benefiting working age populations immediately, regardless of workplace size, work sector, or region of the country. 2010 Wiley-Liss, Inc.

Development of Flight Safety Prediction Methodology for U. S. Naval Safety Center. Revision 1

DTIC Science & Technology

1970-02-01

Safety Center. The methodology develoned encompassed functional analysis of the F-4J aircraft, assessment of the importance of safety- sensitive ... Sensitivity ... ....... . 4-8 V 4.5 Model Implementation ........ ......... . 4-10 4.5.1 Functional Analysis ..... ........... . 4-11 4. 5. 2 Major...Function Sensitivity Assignment ........ ... 4-13 i 4.5.3 Link Dependency Assignment ... ......... . 4-14 4.5.4 Computer Program for Sensitivity

Nondestructive Technique To Assess Embrittlement In Steels

NASA Technical Reports Server (NTRS)

Allison, Sidney G.; Yost, William T.; Cantrell, John H.

1990-01-01

Recent research at NASA Langley Research Center led to identification of nondestructive technique for detection of temper embrittlement in HY80 steel. Measures magnetoacoustic emission associated with reversible motion of domain walls at low magnetic fields. Of interest to engineers responsible for reliability and safety of various dynamically loaded and/or thermally cycled steel parts. Applications include testing of landing gears, naval vessels, and parts subjected to heat, such as those found in steam-pipe fittings, boilers, turbine rotors, and nuclear pressure vessels.

Safety Passage in the Flying Canoes

NASA Technical Reports Server (NTRS)

1984-01-01

Jungle Aviation and Radio Service (JAARS) delivers missionaries to remote outposts under sometimes hazardous flying conditions. A serious accident led JAARS' to initiate a crash survivability research program based on NASA technology. In 1978, JAARS sought help from Langley Research Center and was invited to participate in Langley's crashworthiness program. With assistance from Langley, JAARS developed an impact absorbing aircraft seat designed to minimize crash injury. The seat design is available to all missionary aircraft and JAARS is offering it for commercial manufacture.

Clinical trial uses combination therapy for certain types of non-Hodgkin lymphoma | Center for Cancer Research

Cancer.gov

Researchers are testing the safety of the combination of an experimental drug with rituximab, a standard treatment, for patients with indolent or diffuse large B-cell lymphoma. The antibody is designed to target and block a protein that is present on cancer cells and is used by those cells to protect themselves from your body’s immune system. Blocking the protein may enable your body’s immune system to find and destroy the cancer cells. Read more…

Environmental awareness program development

NASA Technical Reports Server (NTRS)

Steinhauer, David A.

1995-01-01

Work this summer in the Office of Safety, Environment, and Mission Assurance began with a review of current initiatives and environmental projects at the Langley Research Center (LaRC). This involved researching many of the documents on file which detail problems which have occurred as well as various approaches which have been used to address these problems. A large portion of the time was spent interviewing and working with each of the engineers, industrial hygienists and other professionals connected with the Office of Environmental Engineering. A few of the projects I worked on include: Researching environmental compliance, and pollution prevention efforts; touring many of the facilities at LaRC to observe the environmental efforts in the work place; researching equipment needs for the recycling/reclamation center; writing scripts for in-house training videos; working with the video production department to produce a training video; developing e-mail distribution list; developing environmental coordinator's database; and working with others to research logistics of recycling and waste minimization efforts.

Leader-member exchange and safety citizenship behavior: The mediating role of coworker trust.

PubMed

Jiang, Li; Li, Feng; Li, YongJuan; Li, Rui

2017-01-01

To achieve high safety levels, mere compliance with safety regulations is not sufficient; employees must be proactive and demonstrate safety citizenship behaviors. Trust is considered as a mechanism for facilitating the effects of a leader on employee citizenship behaviors. Increasingly research has focused on the role of trust in a safety context; however, the role of coworker trust has been overlooked. The mediating role of coworker trust in the relationship between the leader-member exchange and safety citizenship behavior is the focus of this field study. Front-line employees from an air traffic control center and an airline maintenance department completed surveys measuring leader-member exchange, co-worker trust, and safety citizenship behavior. Structural Equation Modeling revealed affective and cognitive trust in coworkers is influenced by leader-member exchange. A trust-based mediation model where cognitive trust and affective trust mediate the relationship between the leader-member exchange and safety citizenship behavior emerged. Results of this study add to our understanding of the relationship between leader-member exchange and safety behavior. The effect of co-worker trust and the extent to which employees participate in workplace safety practice were identified as critical factors. The findings show that managers need to focus on developing cognitive and affective coworker trust to improve safety citizenship behaviors.

Operating & Environmental Standards « Coast Guard Maritime Commons

Science.gov Websites

: Marine Safety Information Bulletin 03-18, Oily bilge water management This bulletin summarizes key legal updates to Marine Safety Center's ballast water management system website The Marine Safety Center recently updated two tools posted to its ballast water management system website to assist industry when

Quantifying Pilot Contribution to Flight Safety During Dual Generator Failure

NASA Technical Reports Server (NTRS)

Etherington, Timothy J.; Kramer, Lynda J.; Kennedy, Kellie D.; Bailey, Randall E.; Last, Mary Carolyn

2017-01-01

Accident statistics cite flight crew error in over 60% of accidents involving transport category aircraft. Yet, a well-trained and well-qualified pilot is acknowledged as the critical center point of aircraft systems safety and an integral safety component of the entire commercial aviation system. No data currently exists that quantifies the contribution of the flight crew in this role. Neither does data exist for how often the flight crew handles non-normal procedures or system failures on a daily basis in the National Airspace System. A pilot-in-the-loop high fidelity motion simulation study was conducted by the NASA Langley Research Center in partnership with the Federal Aviation Administration (FAA) to evaluate the pilot's contribution to flight safety during normal flight and in response to aircraft system failures. Eighteen crews flew various normal and non-normal procedures over a two-day period and their actions were recorded in response to failures. To quantify the human's contribution, crew complement was used as the experiment independent variable in a between-subjects design. Pilot actions and performance when one of the flight crew was unavailable were also recorded for comparison against the nominal two-crew operations. This paper details diversion decisions, perceived safety of flight, workload, time to complete pertinent checklists, and approach and landing results while dealing with a complete loss of electrical generators. Loss of electrical power requires pilots to complete the flight without automation support of autopilots, flight directors, or auto throttles. For reduced crew complements, the additional workload and perceived safety of flight was considered unacceptable.

Dietary Supplement Research Portfolio at the NIH, 2009–201112

PubMed Central

Garcia-Cazarin, Mary L.; Wambogo, Edwina A.; Regan, Karen S.; Davis, Cindy D.

2014-01-01

The U.S. dietary supplement market increased by 7.5% in 2012 compared with 2011, reaching $32.5 billion in sales. Therefore, federally supported research on dietary supplements is important to determine their health effects, safety, and efficacy. A portfolio analysis was performed across the NIH and the Office of Dietary Supplements (ODS) for fiscal years (FYs) 2009–2011 by using the databases Human Nutrition Research Information Management (HNRIM) and Computer Access to Research on Dietary Supplements (CARDS). The results indicated that total NIH dietary supplement–related funding for FYs 2009–2011 was $855 million ($295 million in 2009, $311 million in 2010, and $249 million in 2011). The institutes and centers with the highest investment in dietary supplement research were as follows: the National Heart, Lung, and Blood Institute ($135 million); the National Cancer Institute ($188 million); the National Center for Complementary and Alternative Medicine ($99 million); the National Institute of Diabetes and Digestive and Kidney Diseases ($68 million); the National Institute of Environmental Health Sciences ($58 million); and the ODS ($32 million). The dietary supplement ingredients receiving the most funding were botanicals (22%), vitamins (20%), lipids (14%), and minerals and trace elements (10%). The top 3 outcome research areas were cancer (61% of total dietary supplement investment), cardiovascular disease (47%), and women’s reproductive health (38%). In FYs 2009, 2010, and 2011, the ODS provided 3.5%, 3.6%, and 4.1%, respectively, of the NIH investment in dietary supplement research. ODS funding focused on cellular, enzymatic, or molecular mechanisms (64% of total ODS funding). This portfolio analysis demonstrates that the NIH has committed substantial funding to dietary supplement research in an effort to expand the scientific knowledge base on the efficacy and safety of dietary supplements. PMID:24523489

Dietary supplement research portfolio at the NIH, 2009-2011.

PubMed

Garcia-Cazarin, Mary L; Wambogo, Edwina A; Regan, Karen S; Davis, Cindy D

2014-04-01

The U.S. dietary supplement market increased by 7.5% in 2012 compared with 2011, reaching $32.5 billion in sales. Therefore, federally supported research on dietary supplements is important to determine their health effects, safety, and efficacy. A portfolio analysis was performed across the NIH and the Office of Dietary Supplements (ODS) for fiscal years (FYs) 2009-2011 by using the databases Human Nutrition Research Information Management (HNRIM) and Computer Access to Research on Dietary Supplements (CARDS). The results indicated that total NIH dietary supplement-related funding for FYs 2009-2011 was $855 million ($295 million in 2009, $311 million in 2010, and $249 million in 2011). The institutes and centers with the highest investment in dietary supplement research were as follows: the National Heart, Lung, and Blood Institute ($135 million); the National Cancer Institute ($188 million); the National Center for Complementary and Alternative Medicine ($99 million); the National Institute of Diabetes and Digestive and Kidney Diseases ($68 million); the National Institute of Environmental Health Sciences ($58 million); and the ODS ($32 million). The dietary supplement ingredients receiving the most funding were botanicals (22%), vitamins (20%), lipids (14%), and minerals and trace elements (10%). The top 3 outcome research areas were cancer (61% of total dietary supplement investment), cardiovascular disease (47%), and women's reproductive health (38%). In FYs 2009, 2010, and 2011, the ODS provided 3.5%, 3.6%, and 4.1%, respectively, of the NIH investment in dietary supplement research. ODS funding focused on cellular, enzymatic, or molecular mechanisms (64% of total ODS funding). This portfolio analysis demonstrates that the NIH has committed substantial funding to dietary supplement research in an effort to expand the scientific knowledge base on the efficacy and safety of dietary supplements.

Caregivers' concerns about judgment and safety of patients with brain injury: a preliminary investigation.

PubMed

Kreutzer, Jeffrey S; Livingston, Lee A; Everley, Rachel S; Gary, Kelli W; Arango-Lasprilla, Juan Carlos; Powell, Victoria D; Marwitz, Jennifer H

2009-08-01

To identify caregivers' most common concerns about the judgment and safety of patients with brain injury in home and community environments. To quantify caregivers' stress levels and their level of comfort leaving patients at home unsupervised and examine the interrelationships between caregivers' safety and judgment ratings, stress levels, and levels of comfort leaving patients unattended. Retrospective, cross-sectional design. Outpatient brain injury neuropsychology clinic at a university medical center. A convenience sample of 121 caregivers of traumatic brain injury survivors at least 1 month postinjury and 18 years of age or older. Scores in 9 domains from the Judgment and Safety Screening Inventory; ratings of stress levels and levels of comfort leaving patients at home unattended derived from the General Health and History Questionnaire. Caregivers' most common judgment and safety-related concerns were in the Travel and Financial domains, with many reflecting patients' memory deficits. Heightened caregiver stress levels were prevalent. Higher levels of concern about judgment and safety were associated with higher stress levels and concerns about leaving patients unattended. Consistent with research on patients with other types of neurological disorders, concerns about driving and financial management among caregivers are prevalent. Additional research is needed to identify the most cost-effective methods of evaluating patients and enabling them to function at their highest level in the community.

Alaska Humans Factors Safety Study: The Southern Coastal Area

NASA Technical Reports Server (NTRS)

Chappell, Sheryl L.; Reynard, William (Technical Monitor)

1995-01-01

At the request of the Alaska Air Carriers Association, researchers from the NASA Aviation Safety Reporting System, at NASA Ames Research Center, conducted a study on aspects of safety in Alaskan Part 135 air taxi operations. An interview form on human factors safety issues was created by a representative team from the FAA-Alaska, NTSB-Alaska, NASA-ASRS, and representatives of the Alaska Air Carriers Association which was subsequently used in the interviews of pilots and managers. Because of the climate and operational differences, the study was broken into two geographical areas, the southern coastal areas and the northern portion of the state. This presentation addresses the southern coastal areas, specifically: Anchorage, Dillingham, King Salmon, Kodiak, Cold Bay, Juneau, and Ketchikan. The interview questions dealt with many of the potential pressures on pilots and managers associated with the daily air taxi operations in Alaska. The impact of the environmental factors such as the lack of available communication, navigation and weather information systems was evaluated. The results of this study will be used by government and industry working in Alaska. These findings will contribute important information on specific Alaska safety issues for eventual incorporation into training materials and policies that will help to assure the safe conduct of air taxi flights in Alaska.

Statistical, epidemiological, and risk-assessment approaches to evaluating safety of vaccines throughout the life cycle at the Food and Drug Administration.

PubMed

Ball, Robert; Horne, Dale; Izurieta, Hector; Sutherland, Andrea; Walderhaug, Mark; Hsu, Henry

2011-05-01

The public health community faces increasing demands for improving vaccine safety while simultaneously increasing the number of vaccines available to prevent infectious diseases. The passage of the US Food and Drug Administration (FDA) Amendment Act of 2007 formalized the concept of life-cycle management of the risks and benefits of vaccines, from early clinical development through many years of use in large numbers of people. Harnessing scientific and technologic advances is necessary to improve vaccine-safety evaluation. The Office of Biostatistics and Epidemiology in the Center for Biologics Evaluation and Research is working to improve the FDA's ability to monitor vaccine safety by improving statistical, epidemiologic, and risk-assessment methods, gaining access to new sources of data, and exploring the use of genomics data. In this article we describe the current approaches, new resources, and future directions that the FDA is taking to improve the evaluation of vaccine safety.

Applying the School Health Index to a Nationally Representative Sample of Schools: Update for 2006

ERIC Educational Resources Information Center

Brener, Nancy D.; Pejavara, Anu; McManus, Tim

2011-01-01

Background: The School Health Index (SHI) is a tool designed to help schools assess the extent to which they are implementing practices included in the research-based guidelines and strategies for school health and safety programs developed by the Centers for Disease Control and Prevention (CDC). CDC previously analyzed data from the 2000 School…

Procedure-Authoring Tool Improves Safety on Oil Rigs

NASA Technical Reports Server (NTRS)

2014-01-01

Dark, cold, and dangerous environments are plentiful in space and on Earth. To ensure safe operations in difficult surroundings, NASA relies heavily on procedures written well ahead of time. Houston-based TRACLabs Inc. worked with Ames Research Center through the SBIR program to create an electronic procedure authoring tool, now used by NASA and companies in the oil and gas industry.

Learning as a shared responsibility: Insights from a series of dialogic workshops with practitioners, leaders, and researchers (Abstract)

Treesearch

Anne Black; Dave Thomas; Jennifer Ziegler; Jim Saveland

2012-01-01

For some time now, the wildland fire community has been interested in 'organizational learning' as a way to improve safety and overall performance. For instance, in the US, federal agencies have established and continue to support the Wildland Fire Lessons Learned Center, sponsored several national conferences and are currently considering how incident...

Learning as a shared responsibility: Insights from a series of dialogic workshops with practitioners, leaders, and researchers

Treesearch

Anne E. Black; Dave Thomas; Jennifer Ziegler; J. Saveland

2012-01-01

For some time now, the wildland fire community has been interested in 'organizational learning' as a way to improve safety and overall performance. For instance, in the US, federal agencies have established the Wildland Fire Lessons Learned Center, sponsored several national conferences, and are currently considering how incident reviews might be used to...

Utilization of the Seniors Falls Investigation Methodology to Identify System-Wide Causes of Falls in Community-Dwelling Seniors

ERIC Educational Resources Information Center

Zecevic, Aleksandra A.; Salmoni, Alan W.; Lewko, John H.; Vandervoort, Anthoney A.; Speechley, Mark

2009-01-01

Purpose: As a highly heterogeneous group, seniors live in complex environments influenced by multiple physical and social structures that affect their safety. Until now, the major approach to falls research has been person centered. However, in industrial settings, the individuals involved in an accident are seen as the inheritors of system…

Interfaces Visualize Data for Airline Safety, Efficiency

NASA Technical Reports Server (NTRS)

2014-01-01

As the A-Train Constellation orbits Earth to gather data, NASA scientists and partners visualize, analyze, and communicate the information. To this end, Langley Research Center awarded SBIR funding to Fairfax, Virginia-based WxAnalyst Ltd. to refine the company's existing user interface for Google Earth to visualize data. Hawaiian Airlines is now using the technology to help manage its flights.

Design validation of an eye-safe scanning aerosol lidar with the Center for Lidar and Atmospheric Sciences Students (CLASS) at Hampton University

NASA Astrophysics Data System (ADS)

Richter, Dale A.; Higdon, N. S.; Ponsardin, Patrick L.; Sanchez, David; Chyba, Thomas H.; Temple, Doyle A.; Gong, Wei; Battle, Russell; Edmondson, Mika; Futrell, Anne; Harper, David; Haughton, Lincoln; Johnson, Demetra; Lewis, Kyle; Payne-Baggott, Renee S.

2002-01-01

ITTs Advanced Engineering and Sciences Division and the Hampton University Center for Lidar and Atmospheric Sciences Students (CLASS) team have worked closely to design, fabricate and test an eye-safe, scanning aerosol-lidar system that can be safely deployed and used by students form a variety of disciplines. CLASS is a 5-year undergraduate- research training program funded by NASA to provide hands-on atmospheric-science and lidar-technology education. The system is based on a 1.5 micron, 125 mJ, 20 Hz eye-safe optical parametric oscillator (OPO) and will be used by the HU researchers and students to evaluate the biological impact of aerosols, clouds, and pollution a variety of systems issues. The system design tasks we addressed include the development of software to calculate eye-safety levels and to model lidar performance, implementation of eye-safety features in the lidar transmitter, optimization of the receiver using optical ray tracing software, evaluation of detectors and amplifiers in the near RI, test of OPO and receiver technology, development of hardware and software for laser and scanner control and video display of the scan region.

Retooling Institutional Support Infrastructure for Clinical Research

PubMed Central

Snyder, Denise C.; Brouwer, Rebecca N.; Ennis, Cory L.; Spangler, Lindsey L.; Ainsworth, Terry L.; Budinger, Susan; Mullen, Catherine; Hawley, Jeffrey; Uhlenbrauck, Gina; Stacy, Mark

2016-01-01

Clinical research activities at academic medical centers are challenging to oversee. Without effective research administration, a continually evolving set of regulatory and institutional requirements can detract investigator and study team attention away from a focus on scientific gain, study conduct, and patient safety. However, even when the need for research administration is recognized, there can be struggles over what form it should take. Central research administration may be viewed negatively, with individual groups preferring to maintain autonomy over processes. Conversely, a proliferation of individualized approaches across an institution can create inefficiencies or invite risk. This article describes experiences establishing a unified research support office at the Duke University School of Medicine based on a framework of customer support. The Duke Office of Clinical Research was formed in 2012 with a vision that research administration at academic medical centers should help clinical investigators navigate the complex research environment and operationalize research ideas. The office provides an array of services that have received high satisfaction ratings. The authors describe the ongoing culture change necessary for success of the unified research support office. Lessons learned from implementation of the Duke Office of Clinical Research may serve as a model for other institutions undergoing a transition to unified research support. PMID:27125563

KSC-02pd1653

NASA Image and Video Library

2002-10-23

KENNEDY SPACE CENTER, FLA. -- KSC employees look over a race car on display during Spaceport Super Safety & Health Day. Dozens of presentations and exhibits across the Center focused attention on safety at work and home.

21 CFR 172.155 - Natamycin (pimaricin).

Code of Federal Regulations, 2010 CFR

2010-04-01

... available from the Division of Product Policy (HFS-206), Center for Food Safety and Applied Nutrition, Food... Center for Food Safety and Applied Nutrition's Library, 5100 Paint Branch Pkwy., College Park, MD 20740...

Transportation Safety Resource Center (TSRC) 2007.

DOT National Transportation Integrated Search

2009-11-01

The Transportation Safety Resource Center (TSRC) is the vital link in a collaborative : partnership created among federal and state transportation agencies, local stakeholders, : academic institutions, and the private sector to provide resources and ...

Sharing adverse drug event data using business intelligence technology.

PubMed

Horvath, Monica M; Cozart, Heidi; Ahmad, Asif; Langman, Matthew K; Ferranti, Jeffrey

2009-03-01

Duke University Health System uses computerized adverse drug event surveillance as an integral part of medication safety at 2 community hospitals and an academic medical center. This information must be swiftly communicated to organizational patient safety stakeholders to find opportunities to improve patient care; however, this process is encumbered by highly manual methods of preparing the data. Following the examples of other industries, we deployed a business intelligence tool to provide dynamic safety reports on adverse drug events. Once data were migrated into the health system data warehouse, we developed census-adjusted reports with user-driven prompts. Drill down functionality enables navigation from aggregate trends to event details by clicking report graphics. Reports can be accessed by patient safety leadership either through an existing safety reporting portal or the health system performance improvement Web site. Elaborate prompt screens allow many varieties of reports to be created quickly by patient safety personnel without consultation with the research analyst. The reduction in research analyst workload because of business intelligence implementation made this individual available to additional patient safety projects thereby leveraging their talents more effectively. Dedicated liaisons are essential to ensure clear communication between clinical and technical staff throughout the development life cycle. Design and development of the business intelligence model for adverse drug event data must reflect the eccentricities of the operational system, especially as new areas of emphasis evolve. Future usability studies examining the data presentation and access model are needed.

Significant improvements in the practice patterns of adult related donor care in US transplant centers

PubMed Central

MBChB, Chloe Anthias; Shaw, Bronwen E; Kiefer, Deidre M; Liesveld, Jane L; Yared, Jean; Kambl, Rammurti T; D'Souza, Anita; Hematti, Peiman; Seftel, Matthew D; Norkin, Maxim; DeFilipp, Zachariah M; Kasow, Kimberly A; Abidi, Muneer H; Savani, Bipin N; Shah, Nirali N; Anderlini, Paolo; Diaz, Miguel A; Malone, Adriana K; Halter, Joerg P; Lazarus, Hillard M; Logan, Brent R; Switzer, Galen E; Pulsipher, Michael A; Confer, Dennis L; O'Donnell, Paul V

2016-01-01

Recent investigations have found a higher incidence of adverse events associated with hematopoietic cell donation in related donors (RDs) who have morbidities that if present in an unrelated donor (UD) would preclude donation. In the UD setting, regulatory standards ensure independent assessment of donors, one of several crucial measures to safeguard donor health and safety. A survey conducted by the Center for International Blood and Marrow Transplant Research (CIBMTR) Donor Health and Safety Working Committee in 2007 reported a potential conflict of interest in >70% US centers, where physicians had simultaneous responsibility for RDs and their recipients. Consequently, several international organizations have endeavored to improve practice through regulations and consensus recommendations. We hypothesized that the changes in the 2012 FACT-JACIE Standards, resulting from the CIBMTR study, will have significantly impacted practice. Accordingly, a follow-up survey of US transplant centers was conducted to assess practice changes since 2007, and investigate additional areas where RD care was predicted to differ from UD care. 73 centers (53%), performing 79% of US RD transplants responded. Significant improvements were observed since the earlier survey; 62% centers now ensure separation of RD and recipient care (P<0.0001). However, this study identifies several areas where RD management does not meet international donor care standards. Particular concerns include counseling and assessment of donors before HLA typing, with 61% centers first disclosing donor HLA results to an individual other than the donor, the use of unlicensed mobilization agents, and the absence of long-term donor follow-up. Recommendations for improvement are described. PMID:26597080

Development and Execution of the RUNSAFE Runway Safety Bayesian Belief Network Model

NASA Technical Reports Server (NTRS)

Green, Lawrence L.

2015-01-01

One focus area of the National Aeronautics and Space Administration (NASA) is to improve aviation safety. Runway safety is one such thrust of investigation and research. The two primary components of this runway safety research are in runway incursion (RI) and runway excursion (RE) events. These are adverse ground-based aviation incidents that endanger crew, passengers, aircraft and perhaps other nearby people or property. A runway incursion is the incorrect presence of an aircraft, vehicle or person on the protected area of a surface designated for the landing and take-off of aircraft; one class of RI events simultaneously involves two aircraft, such as one aircraft incorrectly landing on a runway while another aircraft is taking off from the same runway. A runway excursion is an incident involving only a single aircraft defined as a veer-off or overrun off the runway surface. Within the scope of this effort at NASA Langley Research Center (LaRC), generic RI, RE and combined (RI plus RE, or RUNSAFE) event models have each been developed and implemented as a Bayesian Belief Network (BBN). Descriptions of runway safety issues from the literature searches have been used to develop the BBN models. Numerous considerations surrounding the process of developing the event models have been documented in this report. The event models were then thoroughly reviewed by a Subject Matter Expert (SME) panel through multiple knowledge elicitation sessions. Numerous improvements to the model structure (definitions, node names, node states and the connecting link topology) were made by the SME panel. Sample executions of the final RUNSAFE model have been presented herein for baseline and worst-case scenarios. Finally, a parameter sensitivity analysis for a given scenario was performed to show the risk drivers. The NASA and LaRC research in runway safety event modeling through the use of BBN technology is important for several reasons. These include: 1) providing a means to clearly understand the cause and effect patterns leading to safety issues, incidents and accidents, 2) enabling the prioritization of specialty areas needing more attention to improve aviation safety, and 3) enabling the identification of gaps within NASA's Aviation Safety funding portfolio

Crime, Violence, Discipline, and Safety in U.S. Public Schools. Findings from the School Survey on Crime and Safety: 2009-10. First Look. NCES 2011-320

ERIC Educational Resources Information Center

Neiman, Samantha

2011-01-01

The National Center for Education Statistics collects data on crime and violence in U.S. public schools through the School Survey on Crime and Safety (SSOCS). This First Look report presents findings from the 2009-10 School Survey on Crime and Safety data collection. Developed and managed by the National Center for Education Statistics (NCES)…

American Association of Poison Control Centers

Science.gov Websites

centers in their efforts to prevent and treat poison exposures. Poison centers offer free, confidential ۼ Over-the-Counter Medicine Safety Over-the-Counter Medicine Safety is a 100% free, evidence-based after the close of the data year in the journal Clinical Toxicology and is available for download free

21 CFR 700.27 - Use of prohibited cattle materials in cosmetic products.

Code of Federal Regulations, 2011 CFR

2011-04-01

... examined at the Center for Food Safety and Applied Nutrition's Library, 5100 Paint Branch Pkwy., College... the Center Director, Center for Food Safety and Applied Nutrition, Food and Drug Administration, at... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Use of prohibited cattle materials in cosmetic...

21 CFR 700.27 - Use of prohibited cattle materials in cosmetic products.

Code of Federal Regulations, 2012 CFR

2012-04-01

... examined at the Center for Food Safety and Applied Nutrition's Library, 5100 Paint Branch Pkwy., College... the Center Director, Center for Food Safety and Applied Nutrition, Food and Drug Administration, at... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Use of prohibited cattle materials in cosmetic...

21 CFR 700.27 - Use of prohibited cattle materials in cosmetic products.

Code of Federal Regulations, 2010 CFR

2010-04-01

... examined at the Center for Food Safety and Applied Nutrition's Library, 5100 Paint Branch Pkwy., College... the Center Director, Center for Food Safety and Applied Nutrition, Food and Drug Administration, at... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Use of prohibited cattle materials in cosmetic...

21 CFR 700.27 - Use of prohibited cattle materials in cosmetic products.

Code of Federal Regulations, 2013 CFR

2013-04-01

... examined at the Center for Food Safety and Applied Nutrition's Library, 5100 Paint Branch Pkwy., College... the Center Director, Center for Food Safety and Applied Nutrition, Food and Drug Administration, at... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Use of prohibited cattle materials in cosmetic...

21 CFR 700.27 - Use of prohibited cattle materials in cosmetic products.

Code of Federal Regulations, 2014 CFR

2014-04-01

... examined at the Center for Food Safety and Applied Nutrition's Library, 5100 Paint Branch Pkwy., College... the Center Director, Center for Food Safety and Applied Nutrition, Food and Drug Administration, at... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Use of prohibited cattle materials in cosmetic...

77 FR 43557 - Safety Zone; Gilmerton Bridge Center Span Float-in, Elizabeth River; Norfolk, Portsmouth, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-25

...-AA00 Safety Zone; Gilmerton Bridge Center Span Float-in, Elizabeth River; Norfolk, Portsmouth, and... during the Gilmerton Bridge Center Span Float- in and bridge construction of span placement. This action... Construction, INC will facilitate removal of the existing bascule spans from the Gilmerton Bridge, transport of...

KSC History Project

NASA Technical Reports Server (NTRS)

Dethloff, Henry C.

2001-01-01

The KSC History Project focuses on archival research and oral history interviews on the history of Kennedy Space Center (KSC). Related projects include the preparation of a precis and chapter outline for a proposed book-length narrative history, a bibliography of key primary and secondary resources, a brief monograph overview of the history of KSC, and a monograph on the history of safety at the Center. Finally, there is work on the development of a web page and a personal history data base associated with the oral history project. The KSC History Project has been a joint endeavor between Henry C. Dethloff and Dr. Noble Lee Snaples, Jr.

(NESC) NASA Engineering and Safety Center Orion Heat Shield Carr

NASA Image and Video Library

2014-04-29

(NESC) NASA Engineering and Safety Center Orion Heat Shield Carrier Structure: Titanium Orthogrid heat shield sub-component dynamic test article : person in the photo Jim Jeans (Background: Mike Kirsch, James Ainsworth)

Aircraft Turbine Engine Control Research at NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Garg, Sanjay

2013-01-01

This paper provides an overview of the aircraft turbine engine control research at the NASA Glenn Research Center (GRC). A brief introduction to the engine control problem is first provided with a description of the state-of-the-art control law structure. A historical aspect of engine control development since the 1940s is then provided with a special emphasis on the contributions of GRC. With the increased emphasis on aircraft safety, enhanced performance, and affordability, as well as the need to reduce the environmental impact of aircraft, there are many new challenges being faced by the designers of aircraft propulsion systems. The Controls and Dynamics Branch (CDB) at GRC is leading and participating in various projects to develop advanced propulsion controls and diagnostics technologies that will help meet the challenging goals of NASA Aeronautics Research Mission programs. The rest of the paper provides an overview of the various CDB technology development activities in aircraft engine control and diagnostics, both current and some accomplished in the recent past. The motivation for each of the research efforts, the research approach, technical challenges, and the key progress to date are summarized.

DARPA/USAF/USN J-UCAS X-45A System Demonstration Program: A Review of Flight Test Site Processes and Personnel

NASA Technical Reports Server (NTRS)

Cosentino, Gary B.

2008-01-01

The Joint Unmanned Combat Air Systems (J-UCAS) program is a collaborative effort between the Defense Advanced Research Project Agency (DARPA), the US Air Force (USAF) and the US Navy (USN). Together they have reviewed X-45A flight test site processes and personnel as part of a system demonstration program for the UCAV-ATD Flight Test Program. The goal was to provide a disciplined controlled process for system integration and testing and demonstration flight tests. NASA's Dryden Flight Research Center (DFRC) acted as the project manager during this effort and was tasked with the responsibilities of range and ground safety, the provision of flight test support and infrastructure and the monitoring of technical and engineering tasks. DFRC also contributed their engineering knowledge through their contributions in the areas of autonomous ground taxi control development, structural dynamics testing and analysis and the provision of other flight test support including telemetry data, tracking radars, and communications and control support equipment. The Air Force Flight Test Center acted at the Deputy Project Manager in this effort and was responsible for the provision of system safety support and airfield management and air traffic control services, among other supporting roles. The T-33 served as a J-UCAS surrogate aircraft and demonstrated flight characteristics similar to that of the the X-45A. The surrogate served as a significant risk reduction resource providing mission planning verification, range safety mission assessment and team training, among other contributions.

C-Band Airport Surface Communications System Engineering-Initial High-Level Safety Risk Assessment and Mitigation

NASA Technical Reports Server (NTRS)

Zelkin, Natalie; Henriksen, Stephen

2011-01-01

This document is being provided as part of ITT's NASA Glenn Research Center Aerospace Communication Systems Technical Support (ACSTS) contract: "New ATM Requirements--Future Communications, C-Band and L-Band Communications Standard Development." ITT has completed a safety hazard analysis providing a preliminary safety assessment for the proposed C-band (5091- to 5150-MHz) airport surface communication system. The assessment was performed following the guidelines outlined in the Federal Aviation Administration Safety Risk Management Guidance for System Acquisitions document. The safety analysis did not identify any hazards with an unacceptable risk, though a number of hazards with a medium risk were documented. This effort represents an initial high-level safety hazard analysis and notes the triggers for risk reassessment. A detailed safety hazards analysis is recommended as a follow-on activity to assess particular components of the C-band communication system after the profile is finalized and system rollout timing is determined. A security risk assessment has been performed by NASA as a parallel activity. While safety analysis is concerned with a prevention of accidental errors and failures, the security threat analysis focuses on deliberate attacks. Both processes identify the events that affect operation of the system; and from a safety perspective the security threats may present safety risks.

Biological Effects of Directed Energy

NASA Astrophysics Data System (ADS)

Dayton, Thomas; Beason, Charles; Hitt, M. K.; Rogers, Walter; Cook, Michael

2002-11-01

This Final Report summarizes the biological effects research conducted by Veridian Engineering personnel under contract F41624-96-C-9009 in support of the Air Force Research Laboratory's Radio Frequency Radiation Branch from April 1997 to April 2002. Biological effects research and consultation were provided in five major areas: Active Denial System (also known as Vehicle Mounted Active Denial System), radio frequency radiation (RFR) health and safety, non-lethal weapon biological effects research, the newly formed Joint Non-Lethal Weapons Human Effects Center of Excellence, and Biotechnology. The report is organized by research efforts within the major research areas, providing title, objective, a brief description, relevance to the AF or DoD, funding, and products.

Western Aeronautical Test Range

NASA Technical Reports Server (NTRS)

Sakahara, Robert D.

2008-01-01

NASA's Western Aeronautical Test Range (WATR) is a network of facilities used to support aeronautical research, science missions, exploration system concepts, and space operations. The WATR resides at NASA's Dryden Flight Research Center located at Edwards Air Force Base, California. The WATR is a part of NASA's Corporate Management of Aeronautical Facilities and funded by the Strategic Capability Asset Program (SCAP). It is managed by the Aeronautics Test Program (ATP) of the Aeronautics Research Mission Directorate (ARMD) to provide the right facility at the right time. NASA is a tenant on Edwards Air Force Base and has an agreement with the Air Force Flight Test Center to use the land and airspace controlled by the Department of Defense (DoD). The topics include: 1) The WATR supports a variety of vehicles; 2) Dryden shares airspace with the AFFTC; 3) Restricted airspace, corridors, and special use areas are available for experimental aircraft; 4) WATR Products and Services; 5) WATR Support Configuration; 6) Telemetry Tracking; 7) Time Space Positioning; 8) Video; 9) Voice Communication; 10) Mobile Operations Facilities; 11) Data Processing; 12) Mission Control Center; 13) Real-Time Data Analysis; and 14) Range Safety.

Recent Advances in Durability and Damage Tolerance Methodology at NASA Langley Research Center

NASA Technical Reports Server (NTRS)

Ransom, J. B.; Glaessgen, E. H.; Raju, I. S.; Harris, C. E.

2007-01-01

Durability and damage tolerance (D&DT) issues are critical to the development of lighter, safer and more efficient aerospace vehicles. Durability is largely an economic life-cycle design consideration whereas damage tolerance directly addresses the structural airworthiness (safety) of the vehicle. Both D&DT methodologies must address the deleterious effects of changes in material properties and the initiation and growth of damage that may occur during the vehicle s service lifetime. The result of unanticipated D&DT response is often manifested in the form of catastrophic and potentially fatal accidents. As such, durability and damage tolerance requirements must be rigorously addressed for commercial transport aircraft and NASA spacecraft systems. This paper presents an overview of the recent and planned future research in durability and damage tolerance analytical and experimental methods for both metallic and composite aerospace structures at NASA Langley Research Center (LaRC).

Four Decades of Ground-Breaking Research in the Reproductive and Developmental Sciences: The Infant Primate Research Laboratory at the University of Washington National Primate Research Center

PubMed Central

Burbacher, Thomas M.; Grant, Kimberly S.; Worlein, Julie; Ha, James; Curnow, Eliza; Juul, Sandra; Sackett, Gene P.

2017-01-01

The Infant Primate Research Laboratory (IPRL) was established in the 1970s at the University of Washington as a visionary project of Dr. Gene (Jim) P. Sackett. Supported by a collaboration between the Washington National Primate Research Center and the Center on Human Health and Disability, the IPRL operates under the principle that learning more about the causes of abnormal development in macaque monkeys will provide important insights into mechanisms underlying childhood neurodevelopmental disorders. Over the past forty years, a broad range of research projects have been conducted at the IPRL. Some have described the normal expression of species-typical behaviors in nursery-reared macaques while others have focused on specific issues in perinatal medicine and research. This article will review the unique history of the IPRL and the scientific contributions produced by research conducted in the laboratory. Past and present investigations at the IPRL have explored the consequences of adverse early rearing, low-birth-weight, prematurity, epilepsy, chemical/drug exposure, viral infection, diarrheal disease, vaccine safety, assisted reproductive technologies and perinatal hypoxia on growth and development. New directions of investigation include the production of a transgenic primate model using our embryonic stem cell-based technology to better understand and treat heritable forms of human mental retardation such as fragile X. PMID:23873400

KENNEDY SPACE CENTER, FLA. - Center Director Jim Kennedy (center) shares the kudos for Spaceport Super Safety and Health Day with members of the coordinating committee. Astronaut Barry E. Wilmore (at right) presented the award to Kennedy. Next to Wilmore at right is Dr. Woodrow Whitlow, KSC’s deputy director.

NASA Image and Video Library

2003-10-15

KENNEDY SPACE CENTER, FLA. - Center Director Jim Kennedy (center) shares the kudos for Spaceport Super Safety and Health Day with members of the coordinating committee. Astronaut Barry E. Wilmore (at right) presented the award to Kennedy. Next to Wilmore at right is Dr. Woodrow Whitlow, KSC’s deputy director.

KSC-04PD-2210

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. Center Director Jim Kennedy kicks off Spaceport Super Safety and Health Day with opening ceremonies at the KSC Training Auditorium. Guest speakers included Dr. Pamela Peeke, Navy Com. Stephen E. Iwanowicz, NASAs Dr. Kristine Calderon and Olympic-great Bruce Jenner. Later in the day, employees could visit many vendors exhibits featuring safety and health items. Super Safety and Health Day was initiated at KSC in 1998 to increase awareness of the importance of safety and health among the government and contractor workforce. The theme for this years event was Safety and Health: A Winning Combination.

KSC-2012-5018

NASA Image and Video Library

2012-09-06

CAPE CANAVERAL, Fla. – An eight-member Kick-Start selection panel listens during a presentation by a Kennedy Space Center employee. Seated in the front row, left to right, are Bob Cabana, center director, Joyce Riquelme, director of Center Planning and Development, Susan Kroskey, center chief financial officer, and Josephine Burnett, director of International Space Station Ground Processing and Research. Back row, left to right are Tracy Anania Wetrich, director of Human Resources, Russell Romanella, director of Safety and Mission Assurance, Nancy Bray, deputy director of Center Operations, and Kelvin Manning, center associate director. As Kennedy continues developing programs and infrastructure to become a 21st century spaceport, many employees are devising ways to do their jobs better and more efficiently. On Sept. 6, 2012, 16 Kennedy employees pitched their innovative ideas for improving the center at the Kennedy Kick-Start event. The competition was part of a center-wide effort designed to increase exposure for innovative ideas and encourage their implementation. For more information, visit http://www.nasa.gov/centers/kennedy/news/kick-start_competition.html Photo credit: NASA/Gianni Woods

Center for Nuclear Medicine Research in Alzheimer`s Disease Health Sciences Center, West Virginia University. Environmental Assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-04-01

The Environmental Assessment (EA) of the Center for Nuclear Medicine Research in Alzheimer`s Disease (CNMR) at the Health Sciences Center, at West Virginia University in Morgantown, West Virginia for the construction and operation was prepared by DOE. The EA documents analysis of the environmental and socioeconomic impacts that might occur as a result of these actions, and characterizes potential impacts on the environment. In the EA, DOE presents its evaluation of potential impacts of construction and operation of the CNMR on health and safety of both workers and the public, as well as on the external environment. Construction impacts includemore » the effects of erosion, waste disposal, air emissions, noise, and construction traffic and parking. Operational impacts include the effects of waste generation (domestic, sanitary, hazardous, medical/biological, radioactive and mixed wastes), radiation exposures, air emissions (radioactive, criteria, and air toxics), noise, and new workers. No sensitive resources (wetlands, special sources of groundwater, protected species) exist in the area of project effect.« less

Implementation of safety driving system using e-health and telematics technology.

PubMed

Lee, Youngbum; Lee, Myoungho

2008-08-01

This research aimed to develop a safety driving system using e-health and telematics technology. Biosignal sensors were installed in an automobile to check the driver's health status with an automatic diagnosis system providing health information to the driver. Measured data were sent to the e-health center through a telematics device, and a medical doctor analyzed these data, sending diagnosis and prescription information to the driver. This system recognizes the driver's sleeping, drinking impairment, excitability, and fatigue using biosensors. The system initially provides alerts in the automobile. It also controls the driving environment in the car, searches for a highway service area using Global Positioning System (GPS), and provides additional information for safety driving. If a car accident has occurred, it makes an emergency call to the nearest hospital, emergency center, and insurance company. A conceptual and prototype model for an imbedded system is presented with initial data for driver condition. Such a system could prevent car accidents caused by drivers driving while intoxicated and falling asleep at the wheel using the driver's biosignals measured by biosensors. The system can provide various e-health services using a telematics system to enhance the technical compatibility of the automobile.

Addressing gaps in international blood availability and transfusion safety in low- and middle-income countries: a NHLBI workshop.

PubMed

Custer, Brian; Zou, Shimian; Glynn, Simone A; Makani, Julie; Tayou Tagny, Claude; El Ekiaby, Magdy; Sabino, Ester C; Choudhury, Nabajyoti; Teo, Diana; Nelson, Kenrad; Peprah, Emmanuel; Price, LeShawndra; Engelgau, Michael M

2018-05-01

In April 2017, a workshop sponsored by the National Heart, Lung, and Blood Institute, Division of Blood Diseases and Resources, and the Center for Translation Research and Implementation Science was held to discuss blood availability and transfusion safety in low- and middle-income countries (LMICs). The purpose of the workshop was to identify research opportunities for implementation science (IS) to improve the availability of safe blood and blood components and transfusion practices in LMICs. IS describes the late stages of the translational research spectrum and studies optimal and sustainable strategies to deliver proven-effective interventions. Regional working groups were formed to focus on opportunities and challenges in East Africa, Central/West Africa, Middle East and North Africa, Latin America and the Caribbean, Southeast Asia, Western Pacific Asia, Eastern Europe, and Central Asia. The need for an "adequate supply of safe blood" emerged as the major overriding theme. Among the regional working groups, common cross-cutting themes were evident. The majority of research questions, priorities, and strategies fell into the categories of blood availability, blood transfusion safety, appropriate use of blood, quality systems, health economics and budgeting, and training and education in IS. The workshop also brought into focus inadequate country-level data that can be used as the basis for IS initiatives. A mixed approach of needs assessment and targeted interventions with sufficient evidence base to move toward sustainment is an appropriate next step for blood availability and transfusion safety research in LMICs. © 2018 AABB.

Fundamental approaches for analysis thermal hydraulic parameter for Puspati Research Reactor

NASA Astrophysics Data System (ADS)

Hashim, Zaredah; Lanyau, Tonny Anak; Farid, Mohamad Fairus Abdul; Kassim, Mohammad Suhaimi; Azhar, Noraishah Syahirah

2016-01-01

The 1-MW PUSPATI Research Reactor (RTP) is the one and only nuclear pool type research reactor developed by General Atomic (GA) in Malaysia. It was installed at Malaysian Nuclear Agency and has reached the first criticality on 8 June 1982. Based on the initial core which comprised of 80 standard TRIGA fuel elements, the very fundamental thermal hydraulic model was investigated during steady state operation using the PARET-code. The main objective of this paper is to determine the variation of temperature profiles and Departure of Nucleate Boiling Ratio (DNBR) of RTP at full power operation. The second objective is to confirm that the values obtained from PARET-code are in agreement with Safety Analysis Report (SAR) for RTP. The code was employed for the hot and average channels in the core in order to calculate of fuel's center and surface, cladding, coolant temperatures as well as DNBR's values. In this study, it was found that the results obtained from the PARET-code showed that the thermal hydraulic parameters related to safety for initial core which was cooled by natural convection was in agreement with the designed values and safety limit in SAR.

Software IV and V Research Priorities and Applied Program Accomplishments Within NASA

NASA Technical Reports Server (NTRS)

Blazy, Louis J.

2000-01-01

The mission of this research is to be world-class creators and facilitators of innovative, intelligent, high performance, reliable information technologies that enable NASA missions to (1) increase software safety and quality through error avoidance, early detection and resolution of errors, by utilizing and applying empirically based software engineering best practices; (2) ensure customer software risks are identified and/or that requirements are met and/or exceeded; (3) research, develop, apply, verify, and publish software technologies for competitive advantage and the advancement of science; and (4) facilitate the transfer of science and engineering data, methods, and practices to NASA, educational institutions, state agencies, and commercial organizations. The goals are to become a national Center Of Excellence (COE) in software and system independent verification and validation, and to become an international leading force in the field of software engineering for improving the safety, quality, reliability, and cost performance of software systems. This project addresses the following problems: Ensure safety of NASA missions, ensure requirements are met, minimize programmatic and technological risks of software development and operations, improve software quality, reduce costs and time to delivery, and improve the science of software engineering

KSC-2010-5720

NASA Image and Video Library

2010-11-17

CAPE CANAVERAL, Fla. -- SpaceX Vice President of Mission Assurance and Astronaut Safety Ken Bowersox addresses attendees of the American Astronautical Society's 2010 National Conference held at the Radisson Resort at the Port in Cape Canaveral, Fla. Also on stage (left to right) are, NASA Deputy Associate Administrator of Space Operations Mission Directorate Lynn Cline; NASA Program Integration Manager at Johnson Space Center, Jeff Arend; Lockheed Martin Information Systems & Global Services Program Director Therese Thrift and NASA Commercial Resupply Program Deputy Manager at Johnson Space Center Ford Dillon. This year's conference was titled: International Space Station: The Next Decade - Utilization and Research. The conference was organized with the support of Kennedy and sponsored by The Boeing Company, Honeywell International Inc., Northrop Grumman Corp., Space Florida and the Universities Space Research Association (USRA). Photo credit: NASA/Jim Grossmann

Laser eye injuries among U.S. military personnel

NASA Astrophysics Data System (ADS)

Johnson, Thomas E.; Keeler, Natalie; Wartick, Ardith L.

2003-06-01

In this study reports of laser injuries in all three military services (Air Force, Army and Navy/Marine) are compared. In collecting data for this study laser injury reports provided by Rockwell Laser Industries (RLI), the United States Army Medical Research Detachment of the Walter Reed Army Institute of Research which maintains the Laser Accident and Incident Registry (LAIR), the Food and Drug Administration's Center for Devices and Radiological Health (CDRH), and the three service Safety Centers. We found a total of 29 laser injury reports that met our case definition. Since 1965, when the first injury occurred, there have been 6 Air Force, 15 Army, and 8 Navy/Marine injuries reported. Statistical analysis of data analyzed thus far shows no difference between the services in 8-year risk groupings between 1965-2002.

Current Status of Programs and Research within the NASA Orbital Debris Program Office

NASA Technical Reports Server (NTRS)

Bacon, Jack

2016-01-01

The NASA Orbital Debris Program Office (ODPO) is the world's longest-standing orbital debris research organization. It supports all aspects of international and US national policy-making related to the orbital environment and to spacecraft life cycle requirements. Representing more than just NASA projects, it is the United States' center of expertise in the field. The office continues to advance research in all aspects of orbital debris, including its measurement, modeling, and risk assessment for both orbital and ground safety concerns. This presentation will highlight current activities and recent progress in all aspects of the ODPO's mission.

Bathing an infant

MedlinePlus

National Resource Center for Health and Safety in Child Care and Early Education. Standard 2.2.0.4: Supervision near ... National Resource Center for Health and Safety in Child Care and Early Education; 2011. cfoc.nrckids.org/CFOC/Database/2. ...

German national femtosecond technology project (FST)

NASA Astrophysics Data System (ADS)

Dausinger, Friedrich

2002-06-01

The German federal government started the funding of a national project intended to exploit the potential of femtosecond technology. In a forgoing competition five research consortia had been successful and have started now together with an adjoin research consortium their investigations in the following fields: (i) micro-machining of technical materials for microstructuring and drilling, (ii) medical therapy in: ophthalmology, dentistry, neurology and ear surgery, (iii) metrology, (iv) laser safety, (v) x- ray generation. Lasers, systems and technologies required in these potential fields of applications will be investigated. The program aims at industrial success and is dominated by industrial partners, therefore. The more fundamental research is done in university institutes and research centers.

KSC-2011-6643

NASA Image and Video Library

2011-08-31

CAPE CANAVERAL, Fla. -- The Cape Canaveral Spaceport Mobile Command Center vehicle participates in the aviation safety exercise during Emergency Response Safety Training at the Shuttle Landing Facility, Runway 33, at NASA’s Kennedy Space Center in Florida. The simulated helicopter mishap exercise was conducted to evaluate emergency response and mishap investigations of aircraft at Kennedy. Participants included Air Rescue Fire Fighters, Flight Operations, Disaster Preparedness, Security, and Safety. NASA mandates simulated aviation safety training take place every two years. Photo credit: NASA/Kim Shiflett

Safety, reliability, maintainability and quality provisions for the Space Shuttle program

NASA Technical Reports Server (NTRS)

1990-01-01

This publication establishes common safety, reliability, maintainability and quality provisions for the Space Shuttle Program. NASA Centers shall use this publication both as the basis for negotiating safety, reliability, maintainability and quality requirements with Shuttle Program contractors and as the guideline for conduct of program safety, reliability, maintainability and quality activities at the Centers. Centers shall assure that applicable provisions of the publication are imposed in lower tier contracts. Centers shall give due regard to other Space Shuttle Program planning in order to provide an integrated total Space Shuttle Program activity. In the implementation of safety, reliability, maintainability and quality activities, consideration shall be given to hardware complexity, supplier experience, state of hardware development, unit cost, and hardware use. The approach and methods for contractor implementation shall be described in the contractors safety, reliability, maintainability and quality plans. This publication incorporates provisions of NASA documents: NHB 1700.1 'NASA Safety Manual, Vol. 1'; NHB 5300.4(IA), 'Reliability Program Provisions for Aeronautical and Space System Contractors'; and NHB 5300.4(1B), 'Quality Program Provisions for Aeronautical and Space System Contractors'. It has been tailored from the above documents based on experience in other programs. It is intended that this publication be reviewed and revised, as appropriate, to reflect new experience and to assure continuing viability.

Innovation in the safety net: integrating community health centers through accountable care.

PubMed

Lewis, Valerie A; Colla, Carrie H; Schoenherr, Karen E; Shortell, Stephen M; Fisher, Elliott S

2014-11-01

Safety net primary care providers, including as community health centers, have long been isolated from mainstream health care providers. Current delivery system reforms such as Accountable Care Organizations (ACOs) may either reinforce the isolation of these providers or may spur new integration of safety net providers. This study examines the extent of community health center involvement in ACOs, as well as how and why ACOs are partnering with these safety net primary care providers. Mixed methods study pairing the cross-sectional National Survey of ACOs (conducted 2012 to 2013), followed by in-depth, qualitative interviews with a subset of ACOs that include community health centers (conducted 2013). One hundred and seventy-three ACOs completed the National Survey of ACOs. Executives from 18 ACOs that include health centers participated in in-depth interviews, along with leadership at eight community health centers participating in ACOs. Key survey measures include ACO organizational characteristics, care management and quality improvement capabilities. Qualitative interviews used a semi-structured interview guide. Interviews were recorded and transcribed, then coded for thematic content using NVivo software. Overall, 28% of ACOs include a community health center (CHC). ACOs with CHCs are similar to those without CHCs in organizational structure, care management and quality improvement capabilities. Qualitative results showed two major themes. First, ACOs with CHCs typically represent new relationships or formal partnerships between CHCs and other local health care providers. Second, CHCs are considered valued partners brought into ACOs to expand primary care capacity and expertise. A substantial number of ACOs include CHCs. These results suggest that rather than reinforcing segmentation of safety net providers from the broader delivery system, the ACO model may lead to the integration of safety net primary care providers.

NASA Research Being Shared Through Live, Interactive Video Tours

NASA Technical Reports Server (NTRS)

Petersen, Ruth A.; Zona, Kathleen A.

2001-01-01

On June 2, 2000, the NASA Glenn Research Center Learning Technologies Project (LTP) coordinated the first live remote videoconferencing broadcast from a Glenn facility. The historic event from Glenn's Icing Research Tunnel featured wind tunnel technicians and researchers performing an icing experiment, obtaining results, and discussing the relevance to everyday flight operations and safety. After a brief overview of its history, students were able to "walk through" the tunnel, stand in the control room, and observe a live icing experiment that demonstrated how ice would grow on an airplane wing in flight through an icing cloud. The tour was interactive, with a spirited exchange of questions and explanations between the students and presenters. The virtual tour of the oldest and largest refrigerated icing research tunnel in the world was the second of a series of videoconferencing connections with the AP Physics students at Bay Village High School, Bay Village, Ohio. The first connection, called Aircraft Safety and Icing Research, introduced the Tailplane Icing Program. In an effort to improve aircraft safety by reducing the number of in-flight icing events, Glenn's Icing Branch uses its icing research aircraft to conduct flight tests. The presenter engaged the students in discussions of basic aircraft flight mechanics and the function of the horizontal tailplane, as well as the effect of ice on airfoil (wing or tail) surfaces. A brief video of actual flight footage provided a view of the pilot's actions and reactions and of the horizon during tailplane icing conditions.

Screening methods for chemical warfare agents in environmental samples at the Edgewood area of Aberdeen Proving Ground, Maryland

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jakubowski, E.M.; Borland, M.M.; Norris, L.

1995-06-01

The U.S. Army Edgewood Research, Development and Engineering Center, the U.S. Army Aberdeen Proving Ground Support Activity, Directorate of Safety, Health and the Environment and SciTech Services Inc., an independent contractor, have developed an approach for screening environmental samples for the presence of chemical warfare agents. Since 1918, the Edgewood area of Aberdeen Proving Ground has been a research and testing ground for toxic agent compounds. Since these materials are considered highly toxic, screening for their presence in environmental samples is necessary for safe shipment to contract laboratories for testing by EPA guidelines. The screening ensures worker safety and maintainsmore » U.S. Army standards for transportation of materials potentially contaminated with chemical warfare agents. This paper describes the screening methodology.« less

Surveying wearable human assistive technology for life and safety critical applications: standards, challenges and opportunities.

PubMed

Alam, Muhammad Mahtab; Ben Hamida, Elyes

2014-05-23

In this survey a new application paradigm life and safety for critical operations and missions using wearable Wireless Body Area Networks (WBANs) technology is introduced. This paradigm has a vast scope of applications, including disaster management, worker safety in harsh environments such as roadside and building workers, mobile health monitoring, ambient assisted living and many more. It is often the case that during the critical operations and the target conditions, the existing infrastructure is either absent, damaged or overcrowded. In this context, it is envisioned that WBANs will enable the quick deployment of ad-hoc/on-the-fly communication networks to help save many lives and ensuring people's safety. However, to understand the applications more deeply and their specific characteristics and requirements, this survey presents a comprehensive study on the applications scenarios, their context and specific requirements. It explores details of the key enabling standards, existing state-of-the-art research studies, and projects to understand their limitations before realizing aforementioned applications. Application-specific challenges and issues are discussed comprehensively from various perspectives and future research and development directions are highlighted as an inspiration for new innovative solutions. To conclude, this survey opens up a good opportunity for companies and research centers to investigate old but still new problems, in the realm of wearable technologies, which are increasingly evolving and getting more and more attention recently.

Surveying Wearable Human Assistive Technology for Life and Safety Critical Applications: Standards, Challenges and Opportunities

PubMed Central

Alam, Muhammad Mahtab; Ben Hamida, Elyes

2014-01-01

In this survey a new application paradigm life and safety for critical operations and missions using wearable Wireless Body Area Networks (WBANs) technology is introduced. This paradigm has a vast scope of applications, including disaster management, worker safety in harsh environments such as roadside and building workers, mobile health monitoring, ambient assisted living and many more. It is often the case that during the critical operations and the target conditions, the existing infrastructure is either absent, damaged or overcrowded. In this context, it is envisioned that WBANs will enable the quick deployment of ad-hoc/on-the-fly communication networks to help save many lives and ensuring people's safety. However, to understand the applications more deeply and their specific characteristics and requirements, this survey presents a comprehensive study on the applications scenarios, their context and specific requirements. It explores details of the key enabling standards, existing state-of-the-art research studies, and projects to understand their limitations before realizing aforementioned applications. Application-specific challenges and issues are discussed comprehensively from various perspectives and future research and development directions are highlighted as an inspiration for new innovative solutions. To conclude, this survey opens up a good opportunity for companies and research centers to investigate old but still new problems, in the realm of wearable technologies, which are increasingly evolving and getting more and more attention recently. PMID:24859024

Communication and computing technology in biocontainment laboratories using the NEIDL as a model.

PubMed

McCall, John; Hardcastle, Kath

2014-07-01

The National Emerging Infectious Diseases Laboratories (NEIDL), Boston University, is a globally unique biocontainment research facility housing biosafety level 2 (BSL-2), BSL-3, and BSL-4 laboratories. Located in the BioSquare area at the University's Medical Campus, it is part of a national network of secure facilities constructed to study infectious diseases of major public health concern. The NEIDL allows for basic, translational, and clinical phases of research to be carried out in a single facility with the overall goal of accelerating understanding, treatment, and prevention of infectious diseases. The NEIDL will also act as a center of excellence providing training and education in all aspects of biocontainment research. Within every detail of NEIDL operations is a primary emphasis on safety and security. The ultramodern NEIDL has required a new approach to communications technology solutions in order to ensure safety and security and meet the needs of investigators working in this complex building. This article discusses the implementation of secure wireless networks and private cloud computing to promote operational efficiency, biosecurity, and biosafety with additional energy-saving advantages. The utilization of a dedicated data center, virtualized servers, virtualized desktop integration, multichannel secure wireless networks, and a NEIDL-dedicated Voice over Internet Protocol (VoIP) network are all discussed. © 2014 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.

ASAS Centennial Paper: Developments and future outlook for preharvest food safety.

PubMed

Oliver, S P; Patel, D A; Callaway, T R; Torrence, M E

2009-01-01

The last century of food animal agriculture is a remarkable triumph of scientific research. Knowledge derived through research has resulted in the development and use of new technologies that have increased the efficiency of food production and created a huge animal production and food manufacturing industry capable of feeding the US population while also providing significant quantities of high-quality food for export to other countries. Although the US food supply is among the safest in the world, the US Center for Disease Prevention and Control estimates that 76 million people get sick, more than 300,000 are hospitalized, and 5,000 die each year from foodborne illness. Consequently, preventing foodborne illness and death remains a major public health concern. Challenges to providing a safe, abundant, and nutritious food supply are complex because all aspects of food production, from farm to fork, must be considered. Given the national and international demand and expectations for food safety as well as the formidable challenges of producing and maintaining a safe food supply, food safety research and educational programs have taken on a new urgency. Remarkable progress has been made during the last century. Wisdom from a century of animal agriculture research now includes the realization that on-farm pathogens are intricately associated with animal health and well-being, the production of high-quality food, and profitability. In this review, some of the developments that have occurred over the last few decades are summarized, including types, sources, and concentrations of disease-causing pathogens encountered in food-producing animal environments and their association with food safety; current and future methods to control or reduce foodborne pathogens on the farm; and present and future preharvest food safety research directions. Future scientific breakthroughs will no doubt have a profound impact on animal agriculture and the production of high-quality food, but we will also be faced with moral, ethical, and societal dilemmas that must be reconciled. A strong, science-based approach that addresses all the complex issues involved in continuing to improve food safety and public health is necessary to prevent foodborne illnesses. Not only must research be conducted to solve complex food safety issues, but results of that research must also be communicated effectively to producers and consumers.

KENNEDY SPACE CENTER, FLA. - Employees fill the Training Auditorium for the kickoff presentation for Spaceport Super Safety and Health Day. Along with Center Director Jim Kennedy, guest speakers were Brig. Gen. J. Gregory Pavlovich, 45th Space Wing, Maj. Gen. Kevin Chilton, and Capt. Charles Plumb (USNR retired), who spoke about his experiences in the Navy and as a prisoner of war in Vietnam. Spaceport Super Safety and Health Day is an annual event at KSC and Cape Canaveral Air Force Station dedicated to reinforcing safe and healthful behaviors in the workforce. Safety Awards were also given to individuals and groups.

NASA Image and Video Library

2003-10-15

KENNEDY SPACE CENTER, FLA. - Employees fill the Training Auditorium for the kickoff presentation for Spaceport Super Safety and Health Day. Along with Center Director Jim Kennedy, guest speakers were Brig. Gen. J. Gregory Pavlovich, 45th Space Wing, Maj. Gen. Kevin Chilton, and Capt. Charles Plumb (USNR retired), who spoke about his experiences in the Navy and as a prisoner of war in Vietnam. Spaceport Super Safety and Health Day is an annual event at KSC and Cape Canaveral Air Force Station dedicated to reinforcing safe and healthful behaviors in the workforce. Safety Awards were also given to individuals and groups.

The NASA Dryden Flight Research Center Unmanned Aircraft System Service Capabilities

NASA Technical Reports Server (NTRS)

Bauer, Jeff

2007-01-01

Over 60 years of Unmanned Aircraft System (UAS) expertise at the National Aeronautics and Space Administration (NASA) Dryden Flight Research Center are being leveraged to provide capability and expertise to the international UAS community. The DFRC brings together technical experts, UAS, and an operational environment to provide government and industry a broad capability to conduct research, perform operations, and mature systems, sensors, and regulation. The cornerstone of this effort is the acquisition of both a Global Hawk (Northrop Grumman Corporation, Los Angeles, California) and Predator B (General Atomics Aeronautical Systems, Inc., San Diego, California) unmanned aircraft system (UAS). In addition, a test range for small UAS will allow developers to conduct research and development flights without the need to obtain approval from civil authorities. Finally, experts are available to government and industry to provide safety assessments in support of operations in civil airspace. These services will allow developers to utilize limited resources to their maximum capability in a highly competitive environment.

Translating findings from basic fear research to clinical psychiatry in Puerto Rico

PubMed Central

Quirk, Gregory J.; Martinez, Karen G.; Nazario Rodríguez, Lelis L.

2009-01-01

Recent advances in the neuroscience of classical fear conditioning from both rodent and human studies are beginning to be translated to the psychiatry clinic. In particular, our understanding of fear extinction as a form of “safety learning” holds promise for the treatment of anxiety disorders in which extinction learning is thought to be compromised. The Department of Psychiatry at the UPR, School of Medicine promotes the development of innovative strategies for treating mental health problems. Given the burden resulting from anxiety disorders in Puerto Rico, and the lack of evidence-based treatment practices, there is a pressing need for a future center specializing in the treatment of anxiety related disorders. This center would also serve research and training functions, with the ultimate goal of translating extinction research into clinical practice. This review presents the current developments in extinction research and its relationship to anxiety disorders and treatment. We also analyze the available literature on the epidemiology of anxiety disorders and the existing evidence-based treatments for these conditions. PMID:18246959

Implementation and Effectiveness of a Mailed FIT Outreach Program in Safety Net Clinics

Cancer.gov

Gloria Coronado, PhD, is an epidemiologist and the Mitch Greenlick Endowed Senior Investigator in Health Disparities Research at Kaiser Permanente Center for Health Research in Portland, OR. Her research focuses on understanding and addressing disparities in the occurrence and burden of disease in underserved populations, with a special emphasis on testing cancer prevention intervention in underserved and Medicaid-enrolled populations. She has developed several innovative and cost-effective interventions to improve rates of participation in cancer screening among patients served by community health centers. Her work has led to partnerships with large health plans, state institutions, and clinics who serve migrants and the uninsured. Dr. Coronado received her PhD in epidemiology from the University of Washington and became a research associate professor in the university’s Department of Epidemiology, in addition to receiving training at Stanford. She currently directs or co-directs three programs that use systems-based approaches to raise the rates of colorectal cancer screening in health plans and clinics in Washington, Oregon and California.

75 FR 383 - Canned Pacific Salmon Deviating From Identity Standard; Extension of Temporary Permit for Market...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-05

... of Nutrition, Labeling and Dietary Supplements, Center for Food Safety and Applied Nutrition (HFS-820.... Barbara Schneeman, Director, Office of Nutrition, Labeling and Dietary Supplements, Center for Food Safety...

Marine Safety Center briefing book

DOT National Transportation Integrated Search

1997-10-30

The U.S. Coast Guard Marine Safety Center was established in 1986 as a consolidation of district Merchant Marine Technical Offices. Our offices are located on the sixth floor of the DOT Headquarters building in Washington, DC. This document provides ...

Clinical trial studies drug for pediatric diffuse intrinsic pontine glioma (DIPG) treatment | Center for Cancer Research

Cancer.gov

Diffuse intrinsic pontine gliomas (DIPGs) are difficult to treat and are the leading cause of brain tumor deaths in children. Katherine Warren, M.D., of the Pediatric Oncology Branch is leading a pediatric clinical trial to determine the safety and best dose of panobinostat, a histone deacetylase inhibitor, for slowing or stopping the growth of DIPGs. Read more…