Sample records for saint michaels talbot

  1. Nonlinear Talbot Effect and Its Applications

    NASA Astrophysics Data System (ADS)

    Yang, Zhening

    2018-03-01

    Talbot effect, a lenless self-imaging phenomenon, was first discovered in 1836 by H.F. Talbot. The conventional Talbott effect has been studied for over a hundred years. Recently, the rapid development of optical superlattices has brought a great breakthrough in Talbot effect research. A nonlinear self-imaging phenomenon was found in the periodically poled LiTaO3 (PPLT) crystals. [1][2][3] This nonlinear Talbot effect has applications not only in optics but also in many other fields. For example, the phenomenon is realized by frequency-doubled beams, which offers people a new way to enhance the spatial resolution of the self-images of periodic objects. And by observing the self-image of the second harmonic (SH) field on the sample surface, people can detect the domain structure in the crystal without damaging the sample. Throughout this review paper, an overview of nonlinear Talbot effect and two applications of this phenomenon is presented. Breakthroughs like achieving a super-focused spot and realizing an acousto-optic tunable SH Talbot illuminator will be introduced as well.

  2. Two-dimensional linear and nonlinear Talbot effect from rogue waves.

    PubMed

    Zhang, Yiqi; Belić, Milivoj R; Petrović, Milan S; Zheng, Huaibin; Chen, Haixia; Li, Changbiao; Lu, Keqing; Zhang, Yanpeng

    2015-03-01

    We introduce two-dimensional (2D) linear and nonlinear Talbot effects. They are produced by propagating periodic 2D diffraction patterns and can be visualized as 3D stacks of Talbot carpets. The nonlinear Talbot effect originates from 2D rogue waves and forms in a bulk 3D nonlinear medium. The recurrences of an input rogue wave are observed at the Talbot length and at the half-Talbot length, with a π phase shift; no other recurrences are observed. Differing from the nonlinear Talbot effect, the linear effect displays the usual fractional Talbot images as well. We also find that the smaller the period of incident rogue waves, the shorter the Talbot length. Increasing the beam intensity increases the Talbot length, but above a threshold this leads to a catastrophic self-focusing phenomenon which destroys the effect. We also find that the Talbot recurrence can be viewed as a self-Fourier transform of the initial periodic beam that is automatically performed during propagation. In particular, linear Talbot effect can be viewed as a fractional self-Fourier transform, whereas the nonlinear Talbot effect can be viewed as the regular self-Fourier transform. Numerical simulations demonstrate that the rogue-wave initial condition is sufficient but not necessary for the observation of the effect. It may also be observed from other periodic inputs, provided they are set on a finite background. The 2D effect may find utility in the production of 3D photonic crystals.

  3. System alignment using the Talbot effect

    NASA Astrophysics Data System (ADS)

    Chevallier, Raymond; Le Falher, Eric; Heggarty, Kevin

    1990-08-01

    The Talbot effect is utilized to correct an alignment problem related to a neural network used for image recognition, which required the alignment of a spatial light modulator (SLM) with the input module. A mathematical model which employs the Fresnel diffraction theory is presented to describe the method. The calculation of the diffracted amplitude describes the wavefront sphericity and the original object transmittance function in order to qualify the lateral shift of the Talbot image. Another explanation is set forth in terms of plane-wave illumination in the neural network. Using a Fourier series and by describing planes where all the harmonics are in phase, the reconstruction of Talbot images is explained. The alignment is effective when the lenslet array is aligned on the even Talbot images of the SLM pixels and the incident wave is a plane wave. The alignment is evaluated in terms of source and periodicity errors, tilt of the incident plane waves, and finite object dimensions. The effects of the error sources are concluded to be negligible, the lenslet array is shown to be successfully aligned with the SLM, and other alignment applications are shown to be possible.

  4. Spherical grating based x-ray Talbot interferometry.

    PubMed

    Cong, Wenxiang; Xi, Yan; Wang, Ge

    2015-11-01

    Grating interferometry is a state-of-the-art x-ray imaging approach, which can acquire information on x-ray attenuation, phase shift, and small-angle scattering simultaneously. Phase-contrast imaging and dark-field imaging are very sensitive to microstructural variation and offers superior contrast resolution for biological soft tissues. However, a common x-ray tube is a point-like source. As a result, the popular planar grating imaging configuration seriously restricts the flux of photons and decreases the visibility of signals, yielding a limited field of view. The purpose of this study is to extend the planar x-ray grating imaging theory and methods to a spherical grating scheme for a wider range of preclinical and clinical applications. A spherical grating matches the wave front of a point x-ray source very well, allowing the perpendicular incidence of x-rays on the grating to achieve a higher visibility over a larger field of view than the planer grating counterpart. A theoretical analysis of the Talbot effect for spherical grating imaging is proposed to establish a basic foundation for x-ray spherical gratings interferometry. An efficient method of spherical grating imaging is also presented to extract attenuation, differential phase, and dark-field images in the x-ray spherical grating interferometer. Talbot self-imaging with spherical gratings is analyzed based on the Rayleigh-Sommerfeld diffraction formula, featuring a periodic angular distribution in a polar coordinate system. The Talbot distance is derived to reveal the Talbot self-imaging pattern. Numerical simulation results show the self-imaging phenomenon of a spherical grating interferometer, which is in agreement with the theoretical prediction. X-ray Talbot interferometry with spherical gratings has a significant practical promise. Relative to planar grating imaging, spherical grating based x-ray Talbot interferometry has a larger field of view and improves both signal visibility and dose

  5. 2. View of Pope & Talbot office and general store, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. View of Pope & Talbot office and general store, facing southeast across Rainier Avenue. Walker-Ames house in right background. - Pope & Talbot Office & General Store, Rainier Avenue, Port Gamble, Kitsap County, WA

  6. Spherical grating based x-ray Talbot interferometry

    PubMed Central

    Cong, Wenxiang; Xi, Yan; Wang, Ge

    2015-01-01

    Purpose: Grating interferometry is a state-of-the-art x-ray imaging approach, which can acquire information on x-ray attenuation, phase shift, and small-angle scattering simultaneously. Phase-contrast imaging and dark-field imaging are very sensitive to microstructural variation and offers superior contrast resolution for biological soft tissues. However, a common x-ray tube is a point-like source. As a result, the popular planar grating imaging configuration seriously restricts the flux of photons and decreases the visibility of signals, yielding a limited field of view. The purpose of this study is to extend the planar x-ray grating imaging theory and methods to a spherical grating scheme for a wider range of preclinical and clinical applications. Methods: A spherical grating matches the wave front of a point x-ray source very well, allowing the perpendicular incidence of x-rays on the grating to achieve a higher visibility over a larger field of view than the planer grating counterpart. A theoretical analysis of the Talbot effect for spherical grating imaging is proposed to establish a basic foundation for x-ray spherical gratings interferometry. An efficient method of spherical grating imaging is also presented to extract attenuation, differential phase, and dark-field images in the x-ray spherical grating interferometer. Results: Talbot self-imaging with spherical gratings is analyzed based on the Rayleigh–Sommerfeld diffraction formula, featuring a periodic angular distribution in a polar coordinate system. The Talbot distance is derived to reveal the Talbot self-imaging pattern. Numerical simulation results show the self-imaging phenomenon of a spherical grating interferometer, which is in agreement with the theoretical prediction. Conclusions: X-ray Talbot interferometry with spherical gratings has a significant practical promise. Relative to planar grating imaging, spherical grating based x-ray Talbot interferometry has a larger field of view and

  7. Spherical grating based x-ray Talbot interferometry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cong, Wenxiang, E-mail: congw@rpi.edu, E-mail: xiy2@rpi.edu, E-mail: wangg6@rpi.edu; Xi, Yan, E-mail: congw@rpi.edu, E-mail: xiy2@rpi.edu, E-mail: wangg6@rpi.edu; Wang, Ge, E-mail: congw@rpi.edu, E-mail: xiy2@rpi.edu, E-mail: wangg6@rpi.edu

    2015-11-15

    Purpose: Grating interferometry is a state-of-the-art x-ray imaging approach, which can acquire information on x-ray attenuation, phase shift, and small-angle scattering simultaneously. Phase-contrast imaging and dark-field imaging are very sensitive to microstructural variation and offers superior contrast resolution for biological soft tissues. However, a common x-ray tube is a point-like source. As a result, the popular planar grating imaging configuration seriously restricts the flux of photons and decreases the visibility of signals, yielding a limited field of view. The purpose of this study is to extend the planar x-ray grating imaging theory and methods to a spherical grating scheme formore » a wider range of preclinical and clinical applications. Methods: A spherical grating matches the wave front of a point x-ray source very well, allowing the perpendicular incidence of x-rays on the grating to achieve a higher visibility over a larger field of view than the planer grating counterpart. A theoretical analysis of the Talbot effect for spherical grating imaging is proposed to establish a basic foundation for x-ray spherical gratings interferometry. An efficient method of spherical grating imaging is also presented to extract attenuation, differential phase, and dark-field images in the x-ray spherical grating interferometer. Results: Talbot self-imaging with spherical gratings is analyzed based on the Rayleigh–Sommerfeld diffraction formula, featuring a periodic angular distribution in a polar coordinate system. The Talbot distance is derived to reveal the Talbot self-imaging pattern. Numerical simulation results show the self-imaging phenomenon of a spherical grating interferometer, which is in agreement with the theoretical prediction. Conclusions: X-ray Talbot interferometry with spherical gratings has a significant practical promise. Relative to planar grating imaging, spherical grating based x-ray Talbot interferometry has a larger field of view and

  8. Super Talbot effect in indefinite metamaterial.

    PubMed

    Zhao, Wangshi; Huang, Xiaoyue; Lu, Zhaolin

    2011-08-01

    The Talbot effect (or the self-imaging effect) can be observed for a periodic object with a pitch larger than the diffraction limit of an imaging system, where the paraxial approximation is applied. In this paper, we show that the super Talbot effect can be achieved in an indefinite metamaterial even when the period is much smaller than the diffraction limit in both two-dimensional and three-dimensional numerical simulations, where the paraxial approximation is not applied. This is attributed to the evanescent waves, which carry the information about subwavelength features of the object, can be converted into propagating waves and then conveyed to far field by the metamaterial, where the permittivity in the propagation direction is negative while the transverse ones are positive. The indefinite metamaterial can be approximated by a system of thin, alternating multilayer metal and insulator (MMI) stack. As long as the loss of the metamaterial is small enough, deep subwavelength image size can be obtained in the super Talbot effect.

  9. 3. View of Pope & Talbot office and general store, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. View of Pope & Talbot office and general store, facing southwest, rear of mill office in right foreground, rear of store in left foreground. Walker-Ames house in left background. - Pope & Talbot Office & General Store, Rainier Avenue, Port Gamble, Kitsap County, WA

  10. In-phased second harmonic wave array generation with intra-Talbot-cavity frequency-doubling.

    PubMed

    Hirosawa, Kenichi; Shohda, Fumio; Yanagisawa, Takayuki; Kannari, Fumihiko

    2015-03-23

    The Talbot cavity is one promising method to synchronize the phase of a laser array. However, it does not achieve the lowest array mode with the same phase but the highest array mode with the anti-phase between every two adjacent lasers, which is called out-phase locking. Consequently, their far-field images exhibit 2-peak profiles. We propose intra-Talbot-cavity frequency-doubling. By placing a nonlinear crystal in a Talbot cavity, the Talbot cavity generates an out-phased fundamental wave array, which is converted into an in-phase-locked second harmonic wave array at the nonlinear crystal. We demonstrate numerical calculations and experiments on intra-Talbot-cavity frequency-doubling and obtain an in-phase-locked second harmonic wave array for a Nd:YVO₄ array laser.

  11. The Talbot effect in a metamaterial

    NASA Astrophysics Data System (ADS)

    Nikkhah, H.; Hasan, M.; Hall, T. J.

    2018-02-01

    The effect of anisotropy and spatial dispersion of a metamaterial on the Talbot effect may be engineered in principle. This has profound implications for applications of the Talbot effect such as the design of a multimode interference coupler (MMI). The paper describes how a metamaterial can suppress the modal phase error which otherwise limits the scaling of MMI port dimension. A binary multilayer dielectric material described by the Kronig-Penney model is shown to provide a close approximation to the required dispersion relation. Results of simulations of a multi-slotted waveguide MMI engineered to provide a polarising beam splitter function are given as an example of the method.

  12. Features of Talbot effect on phase diffraction grating

    NASA Astrophysics Data System (ADS)

    Brazhnikov, Denis G.; Danko, Volodymyr P.; Kotov, Myhaylo M.; Kovalenko, Andriy V.

    2018-01-01

    The features of the Talbot effect using the phase diffraction gratings have been considered. A phase grating, unlike an amplitude grating, gives a constant light intensity in the observation plane at a distance multiple to half of the Talbot length ZT. In this case, the subject of interest consists in so-called fractional Talbot effect with the periodic intensity distribution observed in planes shifted from the position nZT/2 (the so-called Fresnel images). Binary phase diffraction gratings with varying phase steps have been investigated. Gratings were made photographically on holographic plates PFG-01. The phase shift was obtained by modulating the emulsion refraction index of the plates. Two types of gratings were used: a square grating with a fill factor of 0.5 and a checkerwise grating (square areas with a bigger and lower refractive index alternate in a checkerboard pattern). By the example of these gratings, the possibility of obtaining in the observation plane an image of a set of equidistant spots with a size smaller than the size of the phase-shifting elements of the grating (the so-called Talbot focusing) has been shown. Clear images of spots with a sufficient signal-to-noise ratio have been obtained for a square grating. Their period was equal to the period of the grating. For a grating with a checkerwise distribution of the refractive index, the spots have been located in positions corresponding to the centres of cells. In addition, the quality of the resulting pattern strongly depended on the magnitude of a grating phase step. As a result of the work, the possibility to obtain Talbot focusing has been shown and the use of this effect to wavefront investigation with a gradient sensor has been demonstrated.

  13. Theory of Talbot lasers

    NASA Astrophysics Data System (ADS)

    Guillet de Chatellus, H.; Lacot, E.; Glastre, W.; Jacquin, O.; Hugon, O.

    2013-09-01

    We provide a theoretical study of frequency-shifted feedback (FSF) lasers, i.e., lasers with an internal frequency shifter, seeded with a monochromatic wave. The resulting spectrum consists in a set of equidistant modes, labeled by n, whose phases vary quadratically with n. We prove the emergence of a temporal fractional Talbot effect, leading to generation of Fourier-transform-limited pulses at a repetition rate tunable by the parameters of the FSF cavity (cavity length and frequency shift per round trip), and limited by the spectral bandwidth of the laser. We characterize in detail the output field of this so-called “Talbot laser” and emphasize its specific intensity fluctuations. We evidence connections with some aspects of number theory by the appearance of Gauss sums and theta series in the expression of the laser field. Our predictions are in full agreement with the experimental results published in Guillet de Chatellus [Opt. ExpressOPEXFF1094-408710.1364/OE.21.015065 21, 15065 (2013)]. Practical applications and limitations are discussed.

  14. Talbot effect of quasi-periodic grating.

    PubMed

    Zhang, Chong; Zhang, Wei; Li, Furui; Wang, Junhong; Teng, Shuyun

    2013-07-20

    Theoretic and experimental studies of the Talbot effect of quasi-periodic gratings are performed in this paper. The diffractions of periodic and quasi-periodic square aperture arrays in Fresnel fields are analyzed according to the scalar diffraction theory. The expressions of the diffraction intensities of two types of quasi-periodic gratings are deduced. Talbot images of the quasi-periodic gratings are predicted to appear at multiple certain distances. The quasi-periodic square aperture arrays are produced with the aid of a liquid crystal light modulator, and the self-images of the quasi-periodic gratings are measured successfully in the experiment. This study indicates that even a structure in short-range disorder may take on the self-imaging effect in a Fresnel field.

  15. Phase-locked array of quantum cascade lasers with an integrated Talbot cavity.

    PubMed

    Wang, Lei; Zhang, Jinchuan; Jia, Zhiwei; Zhao, Yue; Liu, Chuanwei; Liu, Yinghui; Zhai, Shenqiang; Ning, Zhuo; Xu, Xiangang; Liu, Fengqi

    2016-12-26

    We show a phase-locked array of three quantum cascade lasers with an integrated Talbot cavity at one side of the laser array. The coupling scheme is called diffraction coupling. By controlling the length of Talbot to be a quarter of Talbot distance (Zt/4), in-phase mode operation can be selected. The in-phase operation shows great modal stability under different injection currents, from the threshold current to the full power current. The far-field radiation pattern of the in-phase operation contains three lobes, one central maximum lobe and two side lobes. The interval between adjacent lobes is about 10.5°. The output power is about 1.5 times that of a single-ridge laser. Further studies should be taken to achieve better beam performance and reduce optical losses brought by the integrated Talbot cavity.

  16. Talbot-Lau x-ray interferometry for high energy density plasma diagnostic.

    PubMed

    Stutman, D; Finkenthal, M

    2011-11-01

    High resolution density diagnostics are difficult in high energy density laboratory plasmas (HEDLP) experiments due to the scarcity of probes that can penetrate above solid density plasmas. Hard x-rays are one possible probe for such dense plasmas. We study the possibility of applying an x-ray method recently developed for medical imaging, differential phase-contrast with Talbot-Lau interferometers, for the diagnostic of electron density and small-scale hydrodynamic instabilities in HEDLP experiments. The Talbot method uses micro-periodic gratings to measure the refraction and ultra-small angle scatter of x-rays through an object and is attractive for HEDLP diagnostic due to its capability to work with incoherent and polychromatic x-ray sources such as the laser driven backlighters used for HEDLP radiography. Our paper studies the potential of the Talbot method for HEDLP diagnostic, its adaptation to the HEDLP environment, and its extension of high x-ray energy using micro-periodic mirrors. The analysis is illustrated with experimental results obtained using a laboratory Talbot interferometer. © 2011 American Institute of Physics

  17. Fractional Talbot field and of finite gratings: compact analytical formulation.

    PubMed

    Arrizón, V; Rojo-Velázquez, G

    2001-06-01

    We present a compact analytical formulation for the fractional Talbot effect at the paraxial domain of a finite grating. Our results show that laterally shifted distorted images of the grating basic cell form the Fresnel field at a fractional Talbot plane of the grating. Our formulas give the positions of those images and show that they are given by the convolution of the nondistorted cells (modulated by a quadratic phase factor) with the Fourier transform of the finite-grating pupil.

  18. Experimental quantum information processing with the Talbot effect

    NASA Astrophysics Data System (ADS)

    Sawada, K.; Walborn, S. P.

    2018-07-01

    We report a proof of concept experiment illustrating the implementation of several simple quantum logic gates on D-level quantum systems (quDits) using the Talbot effect. A number of QuDit states are encoded into the transverse profile of a paraxial laser beam using a spatial light modulator. These states are transformed through a diagonal phase element and then free-propagation via the fractional Talbot effect, demonstrating the realization of some well-known single quDit gates in quantum computation. Our classical optics experiment allows us to identify several important technical details, and serves as a first experimental step in performing D-dimensional quantum operations with single photons or other quantum systems using this scheme.

  19. Bottlenecks of the wavefront sensor based on the Talbot effect.

    PubMed

    Podanchuk, Dmytro; Kovalenko, Andrey; Kurashov, Vitalij; Kotov, Myhaylo; Goloborodko, Andrey; Danko, Volodymyr

    2014-04-01

    Physical constraints and peculiarities of the wavefront sensing technique, based on the Talbot effect, are discussed. The limitation on the curvature of the measurable wavefront is derived. The requirements to the Fourier spectrum of the periodic mask are formulated. Two kinds of masks are studied for their performance in the wavefront sensor. It is shown that the boundary part of the mask aperture does not contribute to the initial data for wavefront restoration. It is verified by experiment and computer simulation that the performance of the Talbot sensor, which meets established conditions, is similar to that of the Shack-Hartmann sensor.

  20. 46 CFR 7.85 - St. Simons Island, GA to Little Talbot Island, FL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false St. Simons Island, GA to Little Talbot Island, FL. 7.85... BOUNDARY LINES Atlantic Coast § 7.85 St. Simons Island, GA to Little Talbot Island, FL. (a) A line drawn from latitude 31°04.1′ N. longitude 81°16.7′ W. (St. Simons Lighted Whistle Buoy “ST S”) to latitude 30...

  1. Coherent emission from integrated Talbot-cavity quantum cascade lasers.

    PubMed

    Meng, Bo; Qiang, Bo; Rodriguez, Etienne; Hu, Xiao Nan; Liang, Guozhen; Wang, Qi Jie

    2017-02-20

    We report experimental realization of phase-locked quantum cascade laser (QCL) array using a monolithically integrated Talbot cavity. An array with six laser elements at a wavelength of ~4.8 μm shows a maximum peak power of ~4 W which is more than 5 times higher than that of a single ridge laser element and a slope efficiency of 1 W/A at room temperature. Operation of in-phase coherent supermode has been achieved over the whole dynamic range of the Talbot-cavity QCL. The structure was analysed using a straightforward theoretical model, showing quantitatively good agreement with the experimental results. The reduced thermal resistance makes the structure an attractive approach to achieve high beam quality continuous wave QCLs.

  2. Understanding Photography as Applied Chemistry: Using Talbot's Calotype Process to Introduce Chemistry to Design Students

    ERIC Educational Resources Information Center

    Ro¨sch, Esther S.; Helmerdig, Silke

    2017-01-01

    Early photography processes were predestined to combine chemistry and art. William Henry Fox Talbot is one of the early photography pioneers. In 2-3 day workshops, design students without a major background in chemistry are able to define a reproducible protocol for Talbot's gallic acid containing calotype process. With the experimental concept…

  3. Observation of electromagnetically induced Talbot effect in an atomic system

    NASA Astrophysics Data System (ADS)

    Zhang, Zhaoyang; Liu, Xing; Zhang, Dan; Sheng, Jiteng; Zhang, Yiqi; Zhang, Yanpeng; Xiao, Min

    2018-01-01

    The electromagnetically induced Talbot effect (EITE) resulting from the repeated self-reconstruction of a spatially intensity-modulated probe field is experimentally demonstrated in a three-level atomic configuration. The probe beam is launched into an optically induced lattice (established by the interference of two coupling fields) inside a rubidium vapor cell and is diffracted by the electromagnetically induced grating that was formed. The diffraction pattern repeats itself at the planes of integer multiple Talbot lengths. In addition, a fractional EITE is also investigated. The experimental observations agree well with the theoretical predictions. This investigation may potentially pave the way for studying the nonlinear and quantum dynamical features that have been predicted for established periodic optical systems.

  4. Organocatalytic aza-Michael/retro-aza-Michael reaction: pronounced chirality amplification in aza-Michael reaction and racemization via retro-aza-Michael reaction.

    PubMed

    Cai, Yong-Feng; Li, Li; Luo, Meng-Xian; Yang, Ke-Fang; Lai, Guo-Qiao; Jiang, Jian-Xiong; Xu, Li-Wen

    2011-05-01

    A detailed experimental investigation of an aza-Michael reaction of aniline and chalcone is presented. A series of Cinchona alkaloid-derived organocatalysts with different functional groups were prepared and used in the aza-Michael and retro-aza-Michael reaction. There was an interesting finding that a complete reversal of stereoselectivity when a benzoyl group was introduced to the cinchonine and cinchonidine. The chirality amplification vs. time proceeds in the quinine-derived organocatalyst containing silicon-based bulky group, QN-TBS, -catalyzed aza-Michael reaction under solvent-free conditions. In addition, we have demonstrated for the first time that racemization was occurred in suitable solvents under mild conditions due to retro-aza-Michael reaction of the Michael adduct of aniline with chalcone. These indicate the equilibrium of retro-aza-Michael reaction and aza-Michael reaction produce the happening of chirality amplification in aza-Michael reaction and racemization via retro-aza-Michael reaction under different conditions, which would be beneficial to the development of novel chiral catalysts for the aza-Michael reactions. Copyright © 2011 Wiley-Liss, Inc.

  5. A preclinical Talbot-Lau prototype for x-ray dark-field imaging of human-sized objects.

    PubMed

    Hauke, C; Bartl, P; Leghissa, M; Ritschl, L; Sutter, S M; Weber, T; Zeidler, J; Freudenberger, J; Mertelmeier, T; Radicke, M; Michel, T; Anton, G; Meinel, F G; Baehr, A; Auweter, S; Bondesson, D; Gaass, T; Dinkel, J; Reiser, M; Hellbach, K

    2018-06-01

    Talbot-Lau x-ray interferometry provides information about the scattering and refractive properties of an object - in addition to the object's attenuation features. Until recently, this method was ineligible for imaging human-sized objects as it is challenging to adapt Talbot-Lau interferometers (TLIs) to the relevant x-ray energy ranges. In this work, we present a preclinical Talbot-Lau prototype capable of imaging human-sized objects with proper image quality at clinically acceptable dose levels. The TLI is designed to match a setup of clinical relevance as closely as possible. The system provides a scan range of 120 × 30 cm 2 by using a scanning beam geometry. Its ultimate load is 100 kg. High aspect ratios and fine grid periods of the gratings ensure a reasonable setup length and clinically relevant image quality. The system is installed in a university hospital and is, therefore, exposed to the external influences of a clinical environment. To demonstrate the system's capabilities, a full-body scan of a euthanized pig was performed. In addition, freshly excised porcine lungs with an extrinsically provoked pneumothorax were mounted into a human thorax phantom and examined with the prototype. Both examination sequences resulted in clinically relevant image quality - even in the case of a skin entrance air kerma of only 0.3 mGy which is in the range of human thoracic imaging. The presented case of a pneumothorax and a reader study showed that the prototype's dark-field images provide added value for pulmonary diagnosis. We demonstrated that a dedicated design of a Talbot-Lau interferometer can be applied to medical imaging by constructing a preclinical Talbot-Lau prototype. We experienced that the system is feasible for imaging human-sized objects and the phase-stepping approach is suitable for clinical practice. Hence, we conclude that Talbot-Lau x-ray imaging has potential for clinical use and enhances the diagnostic power of medical x-ray imaging.

  6. View from the East: Arab Perceptions of United States Presence and Policy

    DTIC Science & Technology

    2003-02-01

    View from the East: Arab Perceptions of United States Presence and Policy Brent J . Talbot and Michael B. Meyer INSS...IMPLICATIONS FOR US POLICY IN THE MIDDLE EAST, Brent J . Talbot Introduction 1 The Perception Problem 3 The Consensus Issue 11...THE ARAB PERCEPTION AND CONSENSUS PROBLEMS: IMPLICATIONS FOR US POLICY IN THE MIDDLE EAST, Brent J . Talbot EXECUTIVE SUMMARY This paper is a

  7. Single-shot digital holography by use of the fractional Talbot effect.

    PubMed

    Martínez-León, Lluís; Araiza-E, María; Javidi, Bahram; Andrés, Pedro; Climent, Vicent; Lancis, Jesús; Tajahuerce, Enrique

    2009-07-20

    We present a method for recording in-line single-shot digital holograms based on the fractional Talbot effect. In our system, an image sensor records the interference between the light field scattered by the object and a properly codified parallel reference beam. A simple binary two-dimensional periodic grating is used to codify the reference beam generating a periodic three-step phase distribution over the sensor plane by fractional Talbot effect. This provides a method to perform single-shot phase-shifting interferometry at frame rates only limited by the sensor capabilities. Our technique is well adapted for dynamic wavefront sensing applications. Images of the object are digitally reconstructed from the digital hologram. Both computer simulations and experimental results are presented.

  8. Free space and waveguide Talbot effect: phase relations and planar light circuit applications

    NASA Astrophysics Data System (ADS)

    Nikkhah, H.; Zheng, Q.; Hasan, I.; Abdul-Majid, S.; Hall, T. J.

    2012-10-01

    Optical fields that are periodic in the transverse plane self-image periodically as they propagate along the optical axis: a phenomenon known as the Talbot effect. A transfer matrix may be defined that relates the amplitude and phase of point sources placed on a particular grid at the input to their respective multiple images at an image plane. The free-space Talbot effect may be mapped to the waveguide Talbot effect. Applying this mapping to the transfer matrix enables the prediction of the phase and amplitude relations between the ports of a Multimode Interference (MMI) coupler- a planar waveguide device. The transfer matrix approach has not previously been applied to the free-space case and its mapping to the waveguide case provides greater clarity and physical insight into the phase relationships than previous treatments. The paper first introduces the underlying physics of the Talbot effect in free space with emphasis on the positions along the optical axis at which images occur; their multiplicity; and their relative phase relations determined by the Gauss Quadratic Sum of number theory. The analysis is then adapted to predict the phase relationships between the ports of an MMI. These phase relationships are critical to planar light circuit (PLC) applications such as 90° optical hybrids for coherent optical receiver front-ends, external optical I-Q modulators for coherent optical transmitters; and optical phased array switches. These applications are illustrated by results obtained from devices that have been fabricated and tested by the PTLab in Si micro-photonic integration platforms.

  9. Quantum information processing by weaving quantum Talbot carpets

    NASA Astrophysics Data System (ADS)

    Farías, Osvaldo Jiménez; de Melo, Fernando; Milman, Pérola; Walborn, Stephen P.

    2015-06-01

    Single-photon interference due to passage through a periodic grating is considered in a novel proposal for processing D -dimensional quantum systems (quDits) encoded in the spatial degrees of freedom of light. We show that free-space propagation naturally implements basic single-quDit gates by means of the Talbot effect: an intricate time-space carpet of light in the near-field diffraction regime. By adding a diagonal phase gate, we show that a complete set of single-quDit gates can be implemented. We then introduce a spatially dependent beam splitter that allows for projective measurements in the computational basis and can be used for the implementation of controlled operations between two quDits. Universal quantum information processing can then be implemented with linear optics and ancilla photons via postselection and feed-forward following the original proposal of Knill-Laflamme and Milburn. Although we consider photons, our scheme should be directly applicable to a number of other physical systems. Interpretation of the Talbot effect as a quantum logic operation provides a beautiful and interesting way to visualize quantum computation through wave propagation and interference.

  10. 75 FR 28630 - Maryland; Major Disaster and Related Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ..., Howard, Kent, Montgomery, Prince George's, Queen Anne's, Saint Mary's, Talbot, Washington, and Wicomico..., Calvert, Caroline, Carroll, Charles, Dorchester, Frederick, Garrett, Harford, Montgomery, Prince George's...

  11. Self-Focusing and the Talbot Effect in Conformal Transformation Optics.

    PubMed

    Wang, Xiangyang; Chen, Huanyang; Liu, Hui; Xu, Lin; Sheng, Chong; Zhu, Shining

    2017-07-21

    Transformation optics has been used to propose various novel optical devices. With the help of metamaterials, several intriguing designs, such as invisibility cloaks, have been implemented. However, as the basic units should be much smaller than the working wavelengths to achieve the effective material parameters, and the sizes of devices should be much larger than the wavelengths of illumination to work within the light-ray approximation, it is a big challenge to implement an experimental system that works simultaneously for both geometric optics and wave optics. In this Letter, by using a gradient-index microstructured optical waveguide, we realize a device of conformal transformation optics (CTO) and demonstrate its self-focusing property for geometry optics and the Talbot effect for wave optics. In addition, the Talbot effect in such a system has a potential application to transfer digital information without diffraction. Our findings demonstrate the photon controlling ability of CTO in a feasible experiment system.

  12. Self-Focusing and the Talbot Effect in Conformal Transformation Optics

    NASA Astrophysics Data System (ADS)

    Wang, Xiangyang; Chen, Huanyang; Liu, Hui; Xu, Lin; Sheng, Chong; Zhu, Shining

    2017-07-01

    Transformation optics has been used to propose various novel optical devices. With the help of metamaterials, several intriguing designs, such as invisibility cloaks, have been implemented. However, as the basic units should be much smaller than the working wavelengths to achieve the effective material parameters, and the sizes of devices should be much larger than the wavelengths of illumination to work within the light-ray approximation, it is a big challenge to implement an experimental system that works simultaneously for both geometric optics and wave optics. In this Letter, by using a gradient-index microstructured optical waveguide, we realize a device of conformal transformation optics (CTO) and demonstrate its self-focusing property for geometry optics and the Talbot effect for wave optics. In addition, the Talbot effect in such a system has a potential application to transfer digital information without diffraction. Our findings demonstrate the photon controlling ability of CTO in a feasible experiment system.

  13. Quasi-Talbot effect of orbital angular momentum beams for generation of optical vortex arrays by multiplexing metasurface design.

    PubMed

    Gao, Hui; Li, Yang; Chen, Lianwei; Jin, Jinjin; Pu, Mingbo; Li, Xiong; Gao, Ping; Wang, Changtao; Luo, Xiangang; Hong, Minghui

    2018-01-03

    The quasi-Talbot effect of orbital angular momentum (OAM) beams, in which the centers are placed in a rotationally symmetric position, is demonstrated both numerically and experimentally for the first time. Since its multiplication factor is much higher than the conventional fractional Talbot effect, the quasi-Talbot effect can be used in the generation of vortex beam arrays. A metasurface based on this theory was designed and fabricated to test the validity of this assumption. The agreement between the numerical and measured results suggests the practicability of this method to realize vortex beam arrays with high integrated levels, which can open a new door to achieve various potential uses related to optical vortex arrays in integrated optical systems for wide-ranging applications.

  14. High resolution Talbot self-imaging applied to structural characterization of self-assembled monolayers of microspheres.

    PubMed

    Garcia-Sucerquia, J; Alvarez-Palacio, D C; Kreuzer, H J

    2008-09-10

    We report the observation of the Talbot self-imaging effect in high resolution digital in-line holographic microscopy (DIHM) and its application to structural characterization of periodic samples. Holograms of self-assembled monolayers of micron-sized polystyrene spheres are reconstructed at different image planes. The point-source method of DIHM and the consequent high lateral resolution allows the true image (object) plane to be identified. The Talbot effect is then exploited to improve the evaluation of the pitch of the assembly and to examine defects in its periodicity.

  15. Laser Surface Microstructuring of Biocompatible Materials Using a Microlens Array and the Talbot Effect: Evaluation of the Cell Adhesion.

    PubMed

    Aymerich, María; Nieto, Daniel; Álvarez, Ezequiel; Flores-Arias, María T

    2017-02-22

    A laser based technique for microstructuring titanium and tantalum substrates using the Talbot effect and an array of microlenses is presented. By using this hybrid technique; we are able to generate different patterns and geometries on the top surfaces of the biomaterials. The Talbot effect allows us to rapidly make microstructuring, solving the common problems of using microlenses for multipatterning; where the material expelled during the ablation of biomaterials damages the microlens. The Talbot effect permits us to increase the working distance and reduce the period of the patterns. We also demonstrate that the geometries and patterns act as anchor points for cells; affecting the cell adhesion to the metallic substrates and guiding how they spread over the material.

  16. Michael Ulsh | NREL

    Science.gov Websites

    Michael Ulsh Photo of Michael Ulsh Michael Ulsh Manufacturing R&D Project Lead Michael.Ulsh -line quality control, the study of the performance and durability effects of manufacturing defects, and lead for a multi-lab consortium on solution processing and roll-to-roll manufacturing, and is involved

  17. Laser Surface Microstructuring of Biocompatible Materials Using a Microlens Array and the Talbot Effect: Evaluation of the Cell Adhesion

    PubMed Central

    Aymerich, María; Nieto, Daniel; Álvarez, Ezequiel; Flores-Arias, María T.

    2017-01-01

    A laser based technique for microstructuring titanium and tantalum substrates using the Talbot effect and an array of microlenses is presented. By using this hybrid technique; we are able to generate different patterns and geometries on the top surfaces of the biomaterials. The Talbot effect allows us to rapidly make microstructuring, solving the common problems of using microlenses for multipatterning; where the material expelled during the ablation of biomaterials damages the microlens. The Talbot effect permits us to increase the working distance and reduce the period of the patterns. We also demonstrate that the geometries and patterns act as anchor points for cells; affecting the cell adhesion to the metallic substrates and guiding how they spread over the material. PMID:28772574

  18. Experimental research on the feature of an x-ray Talbot-Lau interferometer versus tube accelerating voltage

    NASA Astrophysics Data System (ADS)

    Wang, Sheng-Hao; Margie, P. Olbinado; Atsushi, Momose; Hua-Jie, Han; Hu, Ren-Fang; Wang, Zhi-Li; Gao, Kun; Zhang, Kai; Zhu, Pei-Ping; Wu, Zi-Yu

    2015-06-01

    X-ray Talbot-Lau interferometer has been used most widely to perform x-ray phase-contrast imaging with a conventional low-brilliance x-ray source, and it yields high-sensitivity phase and dark-field images of samples producing low absorption contrast, thus bearing tremendous potential for future clinical diagnosis. In this work, by changing the accelerating voltage of the x-ray tube from 35 kV to 45 kV, x-ray phase-contrast imaging of a test sample is performed at each integer value of the accelerating voltage to investigate the characteristic of an x-ray Talbot-Lau interferometer (located in the Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Japan) versus tube voltage. Experimental results and data analysis show that within a range this x-ray Talbot-Lau interferometer is not sensitive to the accelerating voltage of the tube with a constant fringe visibility of ˜ 44%. This x-ray Talbot-Lau interferometer research demonstrates the feasibility of a new dual energy phase-contrast x-ray imaging strategy and the possibility to collect a refraction spectrum. Project supported by the Major State Basic Research Development Program of China (Grant No. 2012CB825800), the Science Fund for Creative Research Groups, China (Grant No. 11321503), the National Natural Science Foundation of China (Grant Nos. 11179004, 10979055, 11205189, and 11205157), and the Japan-Asia Youth Exchange Program in Science (SAKURA Exchange Program in Science) Administered by the Japan Science and Technology Agency.

  19. Biography for Michael Rossol | NREL

    Science.gov Websites

    Biography for Michael Rossol Michael Rossol Michael Rossol Resource Data Scientist Michael.Rossol @nrel.gov | 303-275-3680 Michael Rossol is a member of the Systems Modeling team within the Systems Modeling

  20. Two African Saints in Medieval Germany.

    ERIC Educational Resources Information Center

    Grimm, Reinhold

    1992-01-01

    The origin and development of two African saints are discussed: Saint Maurice, patron saint of the eastern empire of Otto I; and Caspar, the youngest of the three Magi. Their representation in German art is described and illustrated. (Author/LB)

  1. Talbot effect of the defective grating in deep Fresnel region

    NASA Astrophysics Data System (ADS)

    Teng, Shuyun; Wang, Junhong; Zhang, Wei; Cui, Yuwei

    2015-02-01

    Talbot effect of the grating with different defect is studied theoretically and experimentally in this paper. The defects of grating include the loss of the diffraction unit, the dislocation of the diffraction unit and the modulation of the unit separation. The exact diffraction distributions of three kinds of defective gratings are obtained according to the finite-difference time-domain (FDTD) method. The calculation results show the image of the missing or dislocating unit appears at the Talbot distance (as mentioned in K. Patorski Prog. Opt., 27, 1989, pp.1-108). This is the so-called self-repair ability of grating imaging. In addition, some more phenomena are discovered. The loss or the dislocation of diffraction unit causes the diffraction distortion within a certain radial angle. The regular modulation of unit separation changes the original diffraction, but the new periodicity of the diffraction distribution rebuilds. The self-imaging of grating with smaller random modulation still keeps the partial self-repair ability, and yet this characteristic depends on the modulation degree of defective grating. These diffraction phenomena of the defective gratings are explained by use of the diffraction theory of grating. The practical experiment is also performed and the experimental results confirm the theoretic predictions.

  2. St. René: the Patron Saint of Anaesthetists and a Patron Saint of Canada.

    PubMed

    Calverley, R K

    1980-01-01

    René Goupil, the Patron Saint of Anaesthetists, and a Patron Saint of Canada, was born in Angers, France in 1608 and studied surgery. He joined the Jesuits as a donné or volunteer worker in 1640 and served in the then tiny colony of Quebec as one of the first medical workers of Canada. After earning meritorious praise for his skills, he again volunteered to attend the Hurons at Sainte Marie, a mission far beyond the frontiers. René's canoe party was ambushed. He was captured by the Mohawks and endured eight weeks of cruel torture before being killed on September 29, 1642. René was the first of eight North American martyrs whose dedication was recognized by canonization in 1930. St. René was appointed Patron Saint of Anaesthetists in 1951.

  3. Saint Marina: the protectress of nephrology.

    PubMed

    Eftychiadis, A C; Marketos, S G

    1999-01-01

    Saint virgin and martyr Marina (Margarita) of Antioch in Pisidia (255-270) is recognized as the patron saint of kidney sufferers and the protectress of nephrology. Beginning in the 13th century she heals in particular patients suffering from nephropathies, pregnant women having a difficult childbirth, barren women and sickly children. She protects the patients from every side effect and complication. Saint Marina is represented in hagiography as a victor, defeating the dragon satan, holding a hammer or a cross and wearing a belt around her back in the area of kidneys. According to writers, artists and sculptors the belt is the perceivable means of Saint Marina for the miraculous recovery from and healing of kidney diseases. Therefore, kidney sufferers and pregnant women put belts upon her relics for blessing and then wore them. From the Middle Ages and Renaissance and up to the contemporary period Saint Marina (Margarita) was considered the patron saint of kidney sufferers. Justifiably she is recognized by the modern medical world as the protectress of nephrology.

  4. Onion cell imaging by using Talbot/self-imaging effect

    NASA Astrophysics Data System (ADS)

    Agarwal, Shilpi; Kumar, Varun; Shakher, Chandra

    2017-08-01

    This paper presents the amplitude and phase imaging of onion epidermis cell using the self-imaging capabilities of a grating (Talbot effect) in visible light region. In proposed method, the Fresnel diffraction pattern from the first grating and object is recorded at self-image plane. Fast Fourier Transform (FFT) is used for extracting the 3D amplitude and phase image of onion epidermis cell. The stability of the proposed system, from environmental perturbation as well as its compactness and portability give the proposed system a high potential for several clinical applications.

  5. Nonlinear Talbot effect of rogue waves.

    PubMed

    Zhang, Yiqi; Belić, Milivoj R; Zheng, Huaibin; Chen, Haixia; Li, Changbiao; Song, Jianping; Zhang, Yanpeng

    2014-03-01

    Akhmediev and Kuznetsov-Ma breathers are rogue wave solutions of the nonlinear Schrödinger equation (NLSE). Talbot effect (TE) is an image recurrence phenomenon in the diffraction of light waves. We report the nonlinear TE of rogue waves in a cubic medium. It is different from the linear TE, in that the wave propagates in a NL medium and is an eigenmode of NLSE. Periodic rogue waves impinging on a NL medium exhibit recurrent behavior, but only at the TE length and at the half-TE length with a π-phase shift; the fractional TE is absent. The NL TE is the result of the NL interference of the lobes of rogue wave breathers. This interaction is related to the transverse period and intensity of breathers, in that the bigger the period and the higher the intensity, the shorter the TE length.

  6. 75 FR 38718 - Safety Zone; Sault Sainte Marie 4th of July Fireworks, St. Mary's River, Sault Sainte Marie, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ...-AA00 Safety Zone; Sault Sainte Marie 4th of July Fireworks, St. Mary's River, Sault Sainte Marie, MI... restrict vessels from a portion of the St. Mary's River during the Sault Sainte Marie 4th of July Fireworks... the setup and launching of fireworks in conjunction with the Sault Sainte Marie 4th of July Fireworks...

  7. Wavefront sensor based on the Talbot effect with the precorrected holographic grating.

    PubMed

    Podanchuk, Dmytro; Kurashov, Vitalij; Goloborodko, Andrey; Dan'ko, Volodymyr; Kotov, Myhaylo; Goloborodko, Natalya

    2012-04-01

    A holographic wavefront sensor based on the Talbot effect is proposed. Optical wavefronts are measured by sampling the light amplitude distribution with a two-dimensional (2D) precorrected holographic grating. The factors that allow changing an angular measurement range and a spatial resolution of the sensor are discussed. A comparative analysis with the Shack-Hartmann sensor is illustrated with some experimental results.

  8. Coherent addition of high power broad-area laser diodes with a compact VBG V-shaped external Talbot cavity

    DOE PAGES

    Liu, Bo; Braiman, Yehuda

    2018-02-06

    In this paper, we introduced a compact V-shaped external Talbot cavity for phase locking of high power broad-area laser diodes. The length of compact cavity is ~25 mm. Near diffraction-limit coherent addition of 10 broad-area laser diodes indicated that high quality phase locking was achieved. We measured the near-field emission mode of each individual broad-area laser diode with different feedback, such as a volume Bragg grating and a high reflection mirror. Finally, we found out that the best result of phase locking broad-area laser diodes was achieved by the compact V-shaped external Talbot cavity with volume Bragg grating feedback.

  9. Coherent addition of high power broad-area laser diodes with a compact VBG V-shaped external Talbot cavity

    NASA Astrophysics Data System (ADS)

    Liu, Bo; Braiman, Yehuda

    2018-05-01

    We introduced a compact V-shaped external Talbot cavity for phase locking of high power broad-area laser diodes. The length of compact cavity is ∼25 mm. Near diffraction-limit coherent addition of 10 broad-area laser diodes indicated that high quality phase locking was achieved. We measured the near-field emission mode of each individual broad-area laser diode with different feedback, such as a volume Bragg grating and a high reflection mirror. We found out that the best result of phase locking broad-area laser diodes was achieved by the compact V-shaped external Talbot cavity with volume Bragg grating feedback.

  10. Coherent addition of high power broad-area laser diodes with a compact VBG V-shaped external Talbot cavity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Bo; Braiman, Yehuda

    In this paper, we introduced a compact V-shaped external Talbot cavity for phase locking of high power broad-area laser diodes. The length of compact cavity is ~25 mm. Near diffraction-limit coherent addition of 10 broad-area laser diodes indicated that high quality phase locking was achieved. We measured the near-field emission mode of each individual broad-area laser diode with different feedback, such as a volume Bragg grating and a high reflection mirror. Finally, we found out that the best result of phase locking broad-area laser diodes was achieved by the compact V-shaped external Talbot cavity with volume Bragg grating feedback.

  11. Maniac Talk - Michael Mishchenko

    NASA Image and Video Library

    2015-01-26

    Michael Mishchenko Maniac Lecture, January 26, 2015 NASA climate scientist Dr. Michael I. Mishchenko presented a Maniac Talk entitled "How much first-principle physics do we need in remote-sensing and atmospheric-radiation research." Michael explained his skepticism and how it has shaped his contributions to the disciplines of electromagnetic scattering, radiative transfer, and remote sensing, which have found widespread use.

  12. Talbot-Lau X-ray Deflectometer electron density diagnostic for laser and pulsed power high energy density plasma experiments

    DOE PAGES

    Valdivia, M. P.; Stutman, D.; Stoeckl, C.; ...

    2016-04-21

    Talbot-Lau X-ray Deflectometry has been developed as an electron density diagnostic for High Energy Density plasmas. The technique can deliver x-ray refraction, attenuation, elemental composition, and scatter information from a single Moiré image. An 8 keV Talbot-Lau interferometer was deployed using laser and x-pinch backlighters. Grating survival and electron density mapping was demonstrated for 25-29 J, 8-30 ps laser pulses using copper foil targets. Moire pattern formation and grating survival was also observed using a copper x-pinch driven at 400 kA, ~1 kA/ns. Lastly, these results demonstrate the potential of TXD as an electron density diagnostic for HED plasmas.

  13. Adaptive wavefront sensor based on the Talbot phenomenon.

    PubMed

    Podanchuk, Dmytro V; Goloborodko, Andrey A; Kotov, Myhailo M; Kovalenko, Andrey V; Kurashov, Vitalij N; Dan'ko, Volodymyr P

    2016-04-20

    A new adaptive method of wavefront sensing is proposed and demonstrated. The method is based on the Talbot self-imaging effect, which is observed in an illuminating light beam with strong second-order aberration. Compensation of defocus and astigmatism is achieved with an appropriate choice of size of the rectangular unit cell of the diffraction grating, which is performed iteratively. A liquid-crystal spatial light modulator is used for this purpose. Self-imaging of rectangular grating in the astigmatic light beam is demonstrated experimentally. High-order aberrations are detected with respect to the compensated second-order aberration. The comparative results of wavefront sensing with a Shack-Hartmann sensor and the proposed sensor are adduced.

  14. Saint: a lightweight integration environment for model annotation.

    PubMed

    Lister, Allyson L; Pocock, Matthew; Taschuk, Morgan; Wipat, Anil

    2009-11-15

    Saint is a web application which provides a lightweight annotation integration environment for quantitative biological models. The system enables modellers to rapidly mark up models with biological information derived from a range of data sources. Saint is freely available for use on the web at http://www.cisban.ac.uk/saint. The web application is implemented in Google Web Toolkit and Tomcat, with all major browsers supported. The Java source code is freely available for download at http://saint-annotate.sourceforge.net. The Saint web server requires an installation of libSBML and has been tested on Linux (32-bit Ubuntu 8.10 and 9.04).

  15. High-energy x-ray Talbot-Lau radiography of a human knee

    NASA Astrophysics Data System (ADS)

    Horn, F.; Gelse, K.; Jabari, S.; Hauke, C.; Kaeppler, S.; Ludwig, V.; Meyer, P.; Michel, T.; Mohr, J.; Pelzer, G.; Rieger, J.; Riess, C.; Seifert, M.; Anton, G.

    2017-08-01

    We report on a radiographic measurement of an ex vivo human knee using a grating-based phase-contrast imaging setup and a medical x-ray tube at a tube voltage of 70 kV. The measurement has been carried out using a Talbot-Lau setup that is suitable to achieve a high visibility in the energy regime of medical imaging. In a medical reading by an experienced trauma surgeon signatures of chondrocalcinosis in the medial meniscus have been identified more evidently using the dark-field image in comparison to the conventional attenuation image. The analysis has been carried out at various dose levels down to 0.14 mGy measured as air kerma, which is a dose comparable to clinically used radiographic devices. The diagnosis has been confirmed by a histological analysis of the meniscus tissue. In the introduced high-frequency filtered phase-contrast image the anterior and posterior horn of the medial meniscus and the posterior cruciate ligament have also been visible. Furthermore, atherosclerotic plaque is visible in both imaging modalities, attenuation and dark-field, despite the presence of overlaying bone. This measurement, for the first time, proves the feasibility of Talbot-Lau x-ray imaging at high-energy spectra above 40 kVp and reasonable dose levels with regard to spacious and dense objects.

  16. Public Notice: Saint-Gobain Abrasives, Inc. and Saint-Gobain Ceramics & Plastics, Inc., CWA-01-2016-0057

    EPA Pesticide Factsheets

    Notice of Proposed Assessment of Class II Civil Penalty and Notice of Opportunity for Hearing under Sections 309(g) and 311(b)(6) of the Clean Water Act for Saint-Gobain Abrasives, Inc. and Saint-Gobain Ceramics & Plastics, Inc., CWA-01-2016-0057

  17. Minneapolis-Saint Paul air cargo study

    DOT National Transportation Integrated Search

    2001-12-01

    The Minneapolis-Saint Paul Task Force commissioned this study. It was established to address the apparent decline in air cargo through Minneapolis-Saint Paul airport in recent years. Distribution services, especially international air cargo, are stra...

  18. Marcel Breuer at Saint John's

    ERIC Educational Resources Information Center

    Carlson, Scott

    2008-01-01

    A visitor to Saint John's University and Saint John's Abbey, in north-central Minnesota, sees something of Gothic heritage while standing in front of the abbey church, designed and built around 1960. The church's 112-foot campanile--a trapezoidal slab made of 2,500 tons of steel and concrete--stands boldly in front of a huge concrete honeycomb…

  19. Talbot-Lau x-ray deflectometer electron density diagnostic for laser and pulsed power high energy density plasma experiments (invited)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Valdivia, M. P., E-mail: mpvaldivia@pha.jhu.edu; Stutman, D.; Stoeckl, C.

    2016-11-15

    Talbot-Lau X-ray deflectometry (TXD) has been developed as an electron density diagnostic for High Energy Density (HED) plasmas. The technique can deliver x-ray refraction, attenuation, elemental composition, and scatter information from a single Moiré image. An 8 keV Talbot-Lau interferometer was deployed using laser and x-pinch backlighters. Grating survival and electron density mapping were demonstrated for 25–29 J, 8–30 ps laser pulses using copper foil targets. Moiré pattern formation and grating survival were also observed using a copper x-pinch driven at 400 kA, ∼1 kA/ns. These results demonstrate the potential of TXD as an electron density diagnostic for HED plasmas.

  20. Talbot-Lau x-ray deflectometer electron density diagnostic for laser and pulsed power high energy density plasma experiments (invited).

    PubMed

    Valdivia, M P; Stutman, D; Stoeckl, C; Mileham, C; Begishev, I A; Theobald, W; Bromage, J; Regan, S P; Klein, S R; Muñoz-Cordovez, G; Vescovi, M; Valenzuela-Villaseca, V; Veloso, F

    2016-11-01

    Talbot-Lau X-ray deflectometry (TXD) has been developed as an electron density diagnostic for High Energy Density (HED) plasmas. The technique can deliver x-ray refraction, attenuation, elemental composition, and scatter information from a single Moiré image. An 8 keV Talbot-Lau interferometer was deployed using laser and x-pinch backlighters. Grating survival and electron density mapping were demonstrated for 25-29 J, 8-30 ps laser pulses using copper foil targets. Moiré pattern formation and grating survival were also observed using a copper x-pinch driven at 400 kA, ∼1 kA/ns. These results demonstrate the potential of TXD as an electron density diagnostic for HED plasmas.

  1. Moiré deflectometry using the Talbot-Lau interferometer as refraction diagnostic for high energy density plasmas at energies below 10 keV.

    PubMed

    Valdivia, M P; Stutman, D; Finkenthal, M

    2014-07-01

    The highly localized density gradients expected in High Energy Density (HED) plasma experiments can be characterized by x-ray phase-contrast imaging in addition to conventional attenuation radiography. Moiré deflectometry using the Talbot-Lau grating interferometer setup is an attractive HED diagnostic due to its high sensitivity to refraction induced phase shifts. We report on the adaptation of such a system for operation in the sub-10 keV range by using a combination of free standing and ultrathin Talbot gratings. This new x-ray energy explored matches well the current x-ray backlighters used for HED experiments, while also enhancing phase effects at lower electron densities. We studied the performance of the high magnification, low energy Talbot-Lau interferometer, for single image phase retrieval using Moiré fringe deflectometry. Our laboratory and simulation studies indicate that such a device is able to retrieve object electron densities from phase shift measurements. Using laboratory x-ray sources from 7 to 15 μm size we obtained accurate simultaneous measurements of refraction and attenuation for both sharp and mild electron density gradients.

  2. Michael E. Himmel | NREL

    Science.gov Websites

    E. Himmel Photo of Michael E. Himmel Michael Himmel Senior Research Fellow I-Molecular Biology ;Towards a molecular-level theory of carbohydrate processivity," Curr. Opinion Biotechnol. (2014 University, Department of Biochem. & Molecular Biol., Distinguished Alumnus (2014) Battelle Memorial

  3. The Use of Portfolios in Leadership Education

    ERIC Educational Resources Information Center

    Olsen, Paul E.

    2009-01-01

    This paper discusses the benefits of using student portfolios in undergraduate leadership education at Saint Michael's College. There appears to be a natural link between the use of portfolios as a tool to facilitate and document leadership growth and development. The Business Administration and Accounting Department at Saint Michael's College…

  4. The second-order differential phase contrast and its retrieval for imaging with x-ray Talbot interferometry.

    PubMed

    Yang, Yi; Tang, Xiangyang

    2012-12-01

    The x-ray differential phase contrast imaging implemented with the Talbot interferometry has recently been reported to be capable of providing tomographic images corresponding to attenuation-contrast, phase-contrast, and dark-field contrast, simultaneously, from a single set of projection data. The authors believe that, along with small-angle x-ray scattering, the second-order phase derivative Φ(") (s)(x) plays a role in the generation of dark-field contrast. In this paper, the authors derive the analytic formulae to characterize the contribution made by the second-order phase derivative to the dark-field contrast (namely, second-order differential phase contrast) and validate them via computer simulation study. By proposing a practical retrieval method, the authors investigate the potential of second-order differential phase contrast imaging for extensive applications. The theoretical derivation starts at assuming that the refractive index decrement of an object can be decomposed into δ = δ(s) + δ(f), where δ(f) corresponds to the object's fine structures and manifests itself in the dark-field contrast via small-angle scattering. Based on the paraxial Fresnel-Kirchhoff theory, the analytic formulae to characterize the contribution made by δ(s), which corresponds to the object's smooth structures, to the dark-field contrast are derived. Through computer simulation with specially designed numerical phantoms, an x-ray differential phase contrast imaging system implemented with the Talbot interferometry is utilized to evaluate and validate the derived formulae. The same imaging system is also utilized to evaluate and verify the capability of the proposed method to retrieve the second-order differential phase contrast for imaging, as well as its robustness over the dimension of detector cell and the number of steps in grating shifting. Both analytic formulae and computer simulations show that, in addition to small-angle scattering, the contrast generated by the

  5. Development of grating-based x-ray Talbot interferometry at the advanced photon source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marathe, Shashidhara; Xiao Xianghui; Wojcik, Michael J.

    2012-07-31

    We report on the ongoing effort to develop hard x-ray Talbot interferometry at the Advanced Photon Source (APS), Argonne National Laboratory, USA. We describe the design of the interferometer and preliminary results obtained at 25 keV using a feather and a phantom sample lithographically fabricated of gold. We mention the future developmental goals and applications of this technique as a metrology tool for x-ray optics and beam wavefront characterization.

  6. Moiré deflectometry using the Talbot-Lau interferometer as refraction diagnostic for High Energy Density plasmas at energies below 10 keV

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Valdivia, M. P.; Stutman, D.; Finkenthal, M.

    2014-07-15

    The highly localized density gradients expected in High Energy Density (HED) plasma experiments can be characterized by x-ray phase-contrast imaging in addition to conventional attenuation radiography. Moiré deflectometry using the Talbot-Lau grating interferometer setup is an attractive HED diagnostic due to its high sensitivity to refraction induced phase shifts. We report on the adaptation of such a system for operation in the sub-10 keV range by using a combination of free standing and ultrathin Talbot gratings. This new x-ray energy explored matches well the current x-ray backlighters used for HED experiments, while also enhancing phase effects at lower electron densities.more » We studied the performance of the high magnification, low energy Talbot-Lau interferometer, for single image phase retrieval using Moiré fringe deflectometry. Our laboratory and simulation studies indicate that such a device is able to retrieve object electron densities from phase shift measurements. Using laboratory x-ray sources from 7 to 15 μm size we obtained accurate simultaneous measurements of refraction and attenuation for both sharp and mild electron density gradients.« less

  7. A "Sacra Rappresentazione" of Saint Apollonia's Martyrdom.

    PubMed

    Eramo, Stefano; Natali, Alessio; Bravi, Monia; Cella, Diana; Milia, Egle

    The literary sources of Saint Apollonia's martyrdom and the evolution of Medieval and Renaissance religious drama are presented along with the compendium of a "Sacra Rappresentazione" from Italian Renaissance regarding Saint Apollonia's Martyrdom. Copyright American Academy of the History of Dentistry.

  8. Pulse repetition rate multiplication by Talbot effect in a coaxial fiber

    NASA Astrophysics Data System (ADS)

    Dhingra, Nikhil; Saxena, Geetika Jain; Anand, Jyoti; Sharma, Enakshi K.

    2018-03-01

    We use a coaxial fiber, which is a cylindrical coupled waveguide structure consisting of two concentric cores, the inner rod and an outer ring core as a first order dispersive media to achieve temporal Talbot effect for pulse repetition rate multiplication (PRRM) in high bit rate optical fiber communication. It is observed that for an input Gaussian pulse train with pulse width, 2τ0=1ps at a repetition rate of 40 Gbps (repetition period, T=25ps), an output repetition rate of 640 Gbps can be achieved without significant distortion at a length of 40.92 m.

  9. Towards simultaneous Talbot bands based optical coherence tomography and scanning laser ophthalmoscopy imaging.

    PubMed

    Marques, Manuel J; Bradu, Adrian; Podoleanu, Adrian Gh

    2014-05-01

    We report a Talbot bands-based optical coherence tomography (OCT) system capable of producing longitudinal B-scan OCT images and en-face scanning laser ophthalmoscopy (SLO) images of the human retina in-vivo. The OCT channel employs a broadband optical source and a spectrometer. A gap is created between the sample and reference beams while on their way towards the spectrometer's dispersive element to create Talbot bands. The spatial separation of the two beams facilitates collection by an SLO channel of optical power originating exclusively from the retina, deprived from any contribution from the reference beam. Three different modes of operation are presented, constrained by the minimum integration time of the camera used in the spectrometer and by the galvo-scanners' scanning rate: (i) a simultaneous acquisition mode over the two channels, useful for small size imaging, that conserves the pixel-to-pixel correspondence between them; (ii) a hybrid sequential mode, where the system switches itself between the two regimes and (iii) a sequential "on-demand" mode, where the system can be used in either OCT or SLO regimes for as long as required. The two sequential modes present varying degrees of trade-off between pixel-to-pixel correspondence and independent full control of parameters within each channel. Images of the optic nerve and fovea regions obtained in the simultaneous (i) and in the hybrid sequential mode (ii) are presented.

  10. René Goupil: patron saint of anesthetists.

    PubMed

    Quintal, J

    1995-06-01

    René Goupil, the patron saint of anesthetists, is addressed mainly as a 17th century French surgeon who practiced his art in North America. He is also presented as a Jesuit martyr and saint. The article freely borrows from past writings of Jesuits on René Goupil.

  11. SAINT: A combined simulation language for modeling man-machine systems

    NASA Technical Reports Server (NTRS)

    Seifert, D. J.

    1979-01-01

    SAINT (Systems Analysis of Integrated Networks of Tasks) is a network modeling and simulation technique for design and analysis of complex man machine systems. SAINT provides the conceptual framework for representing systems that consist of discrete task elements, continuous state variables, and interactions between them. It also provides a mechanism for combining human performance models and dynamic system behaviors in a single modeling structure. The SAINT technique is described and applications of the SAINT are discussed.

  12. Prevalence of ciguatoxins in lionfish (Pterois spp.) from Guadeloupe, Saint Martin, and Saint Barthélmy Islands (Caribbean).

    PubMed

    Soliño, Lucía; Widgy, Saha; Pautonnier, Anthony; Turquet, Jean; Loeffler, Christopher R; Flores Quintana, Harold A; Diogène, Jorge

    2015-08-01

    Lionfish (Pterois spp.) are invasive species that have recently spread throughout the Caribbean. Lionfish are available for purchase in local markets for human consumption in several islands of the region. We examined the prevalence of ciguatoxins (CTXs) in lionfish from the French Antilles, a ciguatera-endemic region. The neuroblastoma-2a (N2a) cell assay was used to assess composite cytotoxicity in 120 fish samples collected from the surrounding waters of Guadeloupe (n = 60), Saint Barthélemy Islands (n = 55) and Saint Martin (n = 5). Twenty-seven of these samples exhibited CTX-like activity by the N2a assay. Ciguatoxin (CTX) was confirmed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) in multiple samples that presented highest composite toxicity levels by N2a. Those fish found to contain CTXs were all from Saint Barthélemy. Lionfish from Guadeloupe and Saint Martin did not exhibit toxin activity, although the sample size from Saint Martin was insufficient to draw any conclusions as to the incidence of CTXs. In this study, we provide information about the potential hazard of ciguatera associated with the consumption of lionfish from known endemic areas. We also demonstrate the utility of the cell-based assay combined with LC-MS/MS to assess activity and to provide structural confirmation of CTXs respectively. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Single-Grating Talbot Imaging for Wavefront Sensing and X-Ray Metrology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grizolli, Walan; Shi, Xianbo; Kolodziej, Tomasz

    2017-01-01

    Single-grating Talbot imaging relies on high-spatial-resolution detectors to perform accurate measurements of X-ray beam wavefronts. The wavefront can be retrieved with a single image, and a typical measurement and data analysis can be performed in few seconds. These qualities make it an ideal tool for synchrotron beamline diagnostics and in-situ metrology. The wavefront measurement can be used both to obtain a phase contrast image of an object and to characterize an X-ray beam. In this work, we explore the concept in two cases: at-wavelength metrology of 2D parabolic beryllium lenses and a wavefront sensor using a diamond crystal beam splitter.

  14. Jack Michael's Motivation

    ERIC Educational Resources Information Center

    Miguel, Caio F.

    2013-01-01

    Among many of Jack Michael's contributions to the field of behavior analysis is his behavioral account of motivation. This paper focuses on the concept of "motivating operation" (MO) by outlining its development from Skinner's (1938) notion of "drive." Conceptually, Michael's term helped us change our focus on…

  15. Stopping time: Henry Fox Talbot and the origins of freeze-frame photography.

    PubMed

    Ramalingam, Chitra

    2008-09-01

    As an image-making tool for scientists studying the transient, instantaneous photography has long been seen as opening up a visual realm previously inaccessible to the inferior testimony of the human eye. But when photographic pioneer Henry Fox Talbot took the first photograph of a moving object by the light of an electric spark in 1851, he was guided by existing visual practices designed to create instantaneous vision in the eye itself. Exploring the background behind the peculiar subject of his experiment - a mechanically spinning disc - reveals a hidden prehistory of spark-illuminated photography: physicists' pre-photographic techniques for stopping time.

  16. Towards simultaneous Talbot bands based optical coherence tomography and scanning laser ophthalmoscopy imaging

    PubMed Central

    Marques, Manuel J.; Bradu, Adrian; Podoleanu, Adrian Gh.

    2014-01-01

    We report a Talbot bands-based optical coherence tomography (OCT) system capable of producing longitudinal B-scan OCT images and en-face scanning laser ophthalmoscopy (SLO) images of the human retina in-vivo. The OCT channel employs a broadband optical source and a spectrometer. A gap is created between the sample and reference beams while on their way towards the spectrometer’s dispersive element to create Talbot bands. The spatial separation of the two beams facilitates collection by an SLO channel of optical power originating exclusively from the retina, deprived from any contribution from the reference beam. Three different modes of operation are presented, constrained by the minimum integration time of the camera used in the spectrometer and by the galvo-scanners’ scanning rate: (i) a simultaneous acquisition mode over the two channels, useful for small size imaging, that conserves the pixel-to-pixel correspondence between them; (ii) a hybrid sequential mode, where the system switches itself between the two regimes and (iii) a sequential “on-demand” mode, where the system can be used in either OCT or SLO regimes for as long as required. The two sequential modes present varying degrees of trade-off between pixel-to-pixel correspondence and independent full control of parameters within each channel. Images of the optic nerve and fovea regions obtained in the simultaneous (i) and in the hybrid sequential mode (ii) are presented. PMID:24877006

  17. Interview with J. Michael Thompson

    ERIC Educational Resources Information Center

    Randall, Mary Elisabeth

    2004-01-01

    J. Michael Thompson is the Vice Provost for Enrollment Management and Dean of Admission and Financial Aid at the University of Southern California. J. Michael has worked in higher education for more than 30 years in a variety of roles at small private and mid-sized and large public universities, and now at USC, a large private university. He has…

  18. Visible saints: social cynosures and dysphoria in the Mediterranean tradition.

    PubMed

    Gaines, A D; Farmer, P E

    1986-12-01

    "Visible saints" are individuals in the Mediterranean culture area who lead lives of heroic, exemplary and public suffering. This paper offers an analysis of visible saints as social cynosures as a means of exploring critical cultural psychiatric issues. We examine the changing nature of saintly suffering in the culture area and look at the media through which familiarity with the saints and their passions is developed and maintained. A detailed clinical case study is presented of "Madame Lorca," identified by her peers as a "saint." We focus on a particular illness episode which proved to be an amplification of symptoms of long standing. Psychiatric diagnostic instruments were administered and indicated the presence of severe clinical depression. However, our research suggests that Mme. Lorca's symptomatology reflects culturally specific methods of coping with dysphoric affects and chronic illness. The paper concludes with an exploration of the nature of personal illness as it relates to a wider cultural system of meaning. The findings demonstrate that the visible saint and her symptomatology are part of a cultural system which generates, promotes, patterns and frames the experience of dysphoric affect in a cultural complex quite distinct from that of clinical depression.

  19. The sacred disease and its patron saint.

    PubMed

    Fatović-Ferencić, S; Dürrigl, M A

    2001-08-01

    Although the Hippocratic natural theory of epilepsy as a brain disorder originated around 400 bc , it did not begin to take root until the 18th and 19th centuries, leaving the intervening centuries dominated by mostly supernatural concepts. This article provides historical insight into human behavior when afflicted with disease: supplication to a patron saint, Saint Valentine, a cult that spread throughout Europe.

  20. 78 FR 70027 - Senior Executive Service; Performance Review Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-22

    .... SYKES, MERLE L. SYNAKOWSKI, EDMUND J. TALBOT JR, GERALD L. TAYLOR, CHARLES W. THOMPSON, MICHAEL A..., WILLIAM N. BURROWS, CHARLES W. BUTTRESS, LARRY D. CADIEUX, GENA E. CALBOS, PHILIP T. CALLAHAN, SAMUEL N..., JAMES MELBOURN DURANT, CHARLES K. ECKROADE, WILLIAM A. EDWARDS III, ROBERT E. EHLI, CATHY L. ELKIND...

  1. Maniac Talk - Michael Kurylo

    NASA Image and Video Library

    2016-11-16

    Michael Kurylo Maniac Lecture, November 16, 2016 NASA climate scientist Michael Kurylo presented a Maniac lecture entitled, "An Uncharted Journey: How I Became an Atmospheric Scientist Rather than a Cowboy or a Farmer." Mike described the path that took him from post-WW II housing projects to and through a rural Connecticut neighborhood, how he became convinced about the unrealistic nature of some early naive career dreams, and how he eventually arrived at a career in atmospheric science (research and program management, and their interface with international environmental policy).

  2. Method for promoting Michael addition reactions

    DOEpatents

    Shah, Pankaj V.; Vietti, David E.; Whitman, David William

    2010-09-21

    Homogeneously dispersed solid reaction promoters having an average particle size from 0.01 .mu.m to 500 .mu.m are disclosed for preparing curable mixtures of at least one Michael donor and at least one Michael acceptor. The resulting curable mixtures are useful as coatings, adhesives, sealants and elastomers.

  3. The Saint Louis River Idea-Slam crowd sourcing good ideas ...

    EPA Pesticide Factsheets

    As part of the 2017 Saint Louis River Summit, we propose hosting an “Idea-Slam” using software originally developed by the U.S. Consumer Financial Protection Bureau. Idea-box is an open source online app/website used to collect and surface ideas from members of an organization, or the public in general. Using the app, users login, view a request or challenge for new ideas, can submit their own ideas and/or view, comment and vote on other previously submitted ideas. Initially we will start with three idea request or “challenges” as listed below. The first will be run prior to the Summit to help generate additional challenges that might be added for the summit depending on the results. Initial Idea Challenges:1. (Prior to summit) If you could ask a large group of Saint Louis River focused scientist, stakeholders, managers, politicians and the public a question about the SLR, what would you ask?2. How might we better engage students and educators with the Saint Louis River?3. How might we employ citizen science for the Saint Louis River?The Idea-box app will be available for users two weeks before the Saint Louis Summit. We will e-mail previous summit participants and others an invitation to participate in “The Saint Louis River Idea-Slam” with clear instruction on how to proceed. During the morning of the first day at the Saint Louis Summit we will make a brief announcement about the Idea-Slam (< 2min.), and invite everyone to participate.

  4. Michael J. Fox: Spurring Research on Parkinson's

    MedlinePlus

    ... on. Feature: Parkinson's Disease Michael J. Fox: Spurring Research on Parkinson's Past Issues / Winter 2014 Table of ... founded the Michael J. Fox Foundation for Parkinson's Research in the year 2000. Photo courtesy of Shutterstock " ...

  5. Michael Lawson | NREL

    Science.gov Websites

    NREL's Ocean Energy team, Dr. Michael Lawson focuses on the areas of wave and water current energy goal of developing an open source design and analysis tool for wave energy conversion (WEC) devices

  6. Combining Gabor and Talbot bands techniques to enhance the sensitivity with depth in Fourier domain optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Bradu, Adrian; Marques, Manuel J.; Bouchal, Petr; Podoleanu, Adrian Gh.

    2013-03-01

    The purpose of this study was to show how to favorably mix two e_ects to improve the sensitivity with depth in Fourier domain optical coherence tomography (OCT): Talbot bands (TB) and Gabor-based fusion (GF) technique. TB operation is achieved by directing the two beams, from the object arm and from the reference arm in the OCT interferometer, along parallel separate paths towards the spectrometer. By changing the lateral gap between the two beams in their path towards the spectrometer, the position for the maximum sensitivity versus the optical path difference in the interferometer is adjusted. For five values of the focus position, the gap between the two beams is readjusted to reach maximum sensitivity. Then, similar to the procedure employed in the GF technique, a composite image is formed by edging together the parts of the five images that exhibited maximum brightness. The combined procedure, TB/GF is examined for four different values of the beam diameters of the two beams. Also we demonstrate volumetric FD-OCT images with mirror term attenuation and sensitivity profile shifted towards higher OPD values by applying a Talbot bands configuration.

  7. X-ray phase scanning setup for non-destructive testing using Talbot-Lau interferometer

    NASA Astrophysics Data System (ADS)

    Bachche, S.; Nonoguchi, M.; Kato, K.; Kageyama, M.; Koike, T.; Kuribayashi, M.; Momose, A.

    2016-09-01

    X-ray grating interferometry has a great potential for X-ray phase imaging over conventional X-ray absorption imaging which does not provide significant contrast for weakly absorbing objects and soft biological tissues. X-ray Talbot and Talbot-Lau interferometers which are composed of transmission gratings and measure the differential X-ray phase shifts have gained popularity because they operate with polychromatic beams. In X-ray radiography, especially for nondestructive testing in industrial applications, the feasibility of continuous sample scanning is not yet completely revealed. A scanning setup is frequently advantageous when compared to a direct 2D static image acquisition in terms of field of view, exposure time, illuminating radiation, etc. This paper demonstrates an efficient scanning setup for grating-based Xray phase imaging using laboratory-based X-ray source. An apparatus consisting of an X-ray source that emits X-rays vertically, optical gratings and a photon-counting detector was used with which continuously moving objects across the field of view as that of conveyor belt system can be imaged. The imaging performance of phase scanner was tested by scanning a long continuous moving sample at a speed of 5 mm/s and absorption, differential-phase and visibility images were generated by processing non-uniform moire movie with our specially designed phase measurement algorithm. A brief discussion on the feasibility of phase scanner with scanning setup approach including X-ray phase imaging performance is reported. The successful results suggest a breakthrough for scanning objects those are moving continuously on conveyor belt system non-destructively using the scheme of X-ray phase imaging.

  8. Automated collimation testing by determining the statistical correlation coefficient of Talbot self-images.

    PubMed

    Rana, Santosh; Dhanotia, Jitendra; Bhatia, Vimal; Prakash, Shashi

    2018-04-01

    In this paper, we propose a simple, fast, and accurate technique for detection of collimation position of an optical beam using the self-imaging phenomenon and correlation analysis. Herrera-Fernandez et al. [J. Opt.18, 075608 (2016)JOOPDB0150-536X10.1088/2040-8978/18/7/075608] proposed an experimental arrangement for collimation testing by comparing the period of two different self-images produced by a single diffraction grating. Following their approach, we propose a testing procedure based on correlation coefficient (CC) for efficient detection of variation in the size and fringe width of the Talbot self-images and thereby the collimation position. When the beam is collimated, the physical properties of the self-images of the grating, such as its size and fringe width, do not vary from one Talbot plane to the other and are identical; the CC is maximum in such a situation. For the de-collimated position, the size and fringe width of the self-images vary, and correspondingly the CC decreases. Hence, the magnitude of CC is a measure of degree of collimation. Using the method, we could set the collimation position to a resolution of 1 μm, which relates to ±0.25   μ    radians in terms of collimation angle (for testing a collimating lens of diameter 46 mm and focal length 300 mm). In contrast to most collimation techniques reported to date, the proposed technique does not require a translation/rotation of the grating, use of complicated phase evaluation algorithms, or an intricate method for determination of period of the grating or its self-images. The technique is fully automated and provides high resolution and precision.

  9. Diffraction-Induced Bidimensional Talbot Self-Imaging with Full Independent Period Control

    NASA Astrophysics Data System (ADS)

    Guillet de Chatellus, Hugues; Romero Cortés, Luis; Deville, Antonin; Seghilani, Mohamed; Azaña, José

    2017-03-01

    We predict, formulate, and observe experimentally a generalized version of the Talbot effect that allows one to create diffraction-induced self-images of a periodic two-dimensional (2D) waveform with arbitrary control of the image spatial periods. Through the proposed scheme, the periods of the output self-image are multiples of the input ones by any desired integer or fractional factor, and they can be controlled independently across each of the two wave dimensions. The concept involves conditioning the phase profile of the input periodic wave before free-space diffraction. The wave energy is fundamentally preserved through the self-imaging process, enabling, for instance, the possibility of the passive amplification of the periodic patterns in the wave by a purely diffractive effect, without the use of any active gain.

  10. Diffraction-Induced Bidimensional Talbot Self-Imaging with Full Independent Period Control.

    PubMed

    Guillet de Chatellus, Hugues; Romero Cortés, Luis; Deville, Antonin; Seghilani, Mohamed; Azaña, José

    2017-03-31

    We predict, formulate, and observe experimentally a generalized version of the Talbot effect that allows one to create diffraction-induced self-images of a periodic two-dimensional (2D) waveform with arbitrary control of the image spatial periods. Through the proposed scheme, the periods of the output self-image are multiples of the input ones by any desired integer or fractional factor, and they can be controlled independently across each of the two wave dimensions. The concept involves conditioning the phase profile of the input periodic wave before free-space diffraction. The wave energy is fundamentally preserved through the self-imaging process, enabling, for instance, the possibility of the passive amplification of the periodic patterns in the wave by a purely diffractive effect, without the use of any active gain.

  11. Occurrences of whale shark (Rhincodon typus Smith, 1828) in the Saint Peter and Saint Paul archipelago, Brazil.

    PubMed

    Hazin, F H V; Vaske Júnior, T; Oliveira, P G; Macena, B C L; Carvalho, F

    2008-05-01

    The Saint Peter and Saint Paul Archipelago in the central tropical Atlantic, is an important ground of whale sharks that are commonly sighted throughout the year close to the fishing boats in the adjacencies of the islands. In sightings reported between February 2000 and November 2005, the lengths of the individuals ranged between 1.8 to 14.0 m. The causes of these concentrations in the archipelago are still unclear, once there are no upwellings and plankton concentrations for feeding, and no reproductive activities were reported. Nevertheless, they could be associated to the spawning period of the abundant flying fishes, mainly in the first semester, when sightings were more frequent.

  12. Complex dark-field contrast and its retrieval in x-ray phase contrast imaging implemented with Talbot interferometry.

    PubMed

    Yang, Yi; Tang, Xiangyang

    2014-10-01

    Under the existing theoretical framework of x-ray phase contrast imaging methods implemented with Talbot interferometry, the dark-field contrast refers to the reduction in interference fringe visibility due to small-angle x-ray scattering of the subpixel microstructures of an object to be imaged. This study investigates how an object's subpixel microstructures can also affect the phase of the intensity oscillations. Instead of assuming that the object's subpixel microstructures distribute in space randomly, the authors' theoretical derivation starts by assuming that an object's attenuation projection and phase shift vary at a characteristic size that is not smaller than the period of analyzer grating G₂ and a characteristic length dc. Based on the paraxial Fresnel-Kirchhoff theory, the analytic formulae to characterize the zeroth- and first-order Fourier coefficients of the x-ray irradiance recorded at each detector cell are derived. Then the concept of complex dark-field contrast is introduced to quantify the influence of the object's microstructures on both the interference fringe visibility and the phase of intensity oscillations. A method based on the phase-attenuation duality that holds for soft tissues and high x-ray energies is proposed to retrieve the imaginary part of the complex dark-field contrast for imaging. Through computer simulation study with a specially designed numerical phantom, they evaluate and validate the derived analytic formulae and the proposed retrieval method. Both theoretical analysis and computer simulation study show that the effect of an object's subpixel microstructures on x-ray phase contrast imaging method implemented with Talbot interferometry can be fully characterized by a complex dark-field contrast. The imaginary part of complex dark-field contrast quantifies the influence of the object's subpixel microstructures on the phase of intensity oscillations. Furthermore, at relatively high energies, for soft tissues it can be

  13. Earthquake Magnitude Relationships for the Saint Peter and Saint Paul Archipelago, Equatorial Atlantic

    NASA Astrophysics Data System (ADS)

    de Melo, Guilherme W. S.; do Nascimento, Aderson F.

    2018-03-01

    We have investigated several relationships between ML, M(NEIC) and Mw for the earthquakes locally recorded in the Saint Peter and Saint Paul Archipelago (SPSPA), Equatorial Atlantic. Because we only have one station in the area, we could not derive attenuation relations for events recorded at different distances at different stations. Our approach was then to compare our ML estimates with magnitudes reported by NEIC. This approach produced acceptable results particularly for epicentral distance smaller than 100 km. For distances greater that 100 km, there is a systematic increase in the residuals probable due to the lack of station correction and our inability to accurately estimate Q. We also investigate the Mw—M(NEIC) relationship. We find that Mw estimates using S-wave produce smaller residuals when compared with both M(NEIC). Finally, we also investigate the ML—Mw relationship and observe that given the data set we have, the 1:1 holds. We believe that the use of the present methodologies provide consistent magnitude estimates between all the magnitudes investigated that could be used to better assess seismic hazard in the region.

  14. Earthquake Magnitude Relationships for the Saint Peter and Saint Paul Archipelago, Equatorial Atlantic

    NASA Astrophysics Data System (ADS)

    de Melo, Guilherme W. S.; do Nascimento, Aderson F.

    2017-12-01

    We have investigated several relationships between ML, M(NEIC) and Mw for the earthquakes locally recorded in the Saint Peter and Saint Paul Archipelago (SPSPA), Equatorial Atlantic. Because we only have one station in the area, we could not derive attenuation relations for events recorded at different distances at different stations. Our approach was then to compare our ML estimates with magnitudes reported by NEIC. This approach produced acceptable results particularly for epicentral distance smaller than 100 km. For distances greater that 100 km, there is a systematic increase in the residuals probable due to the lack of station correction and our inability to accurately estimate Q. We also investigate the Mw—M(NEIC) relationship. We find that Mw estimates using S-wave produce smaller residuals when compared with both M(NEIC). Finally, we also investigate the ML—Mw relationship and observe that given the data set we have, the 1:1 holds. We believe that the use of the present methodologies provide consistent magnitude estimates between all the magnitudes investigated that could be used to better assess seismic hazard in the region.

  15. Glancing angle Talbot-Lau grating interferometers for phase contrast imaging at high x-ray energy

    NASA Astrophysics Data System (ADS)

    Stutman, D.; Finkenthal, M.

    2012-08-01

    A Talbot-Lau interferometer is demonstrated using micro-periodic gratings inclined at a glancing angle along the light propagation direction. Due to the increase in the effective thickness of the absorption gratings, the device enables differential phase contrast imaging at high x-ray energy, with improved fringe visibility (contrast). For instance, at 28° glancing angle, we obtain up to ˜35% overall interferometer contrast with a spectrum having ˜43 keV mean energy, suitable for medical applications. In addition, glancing angle interferometers could provide high contrast at energies above 100 keV, enabling industrial and security applications of phase contrast imaging.

  16. Umbilical hernia with cholelithiasis and hiatal hernia: a clinical entity similar to Saint's triad.

    PubMed

    Yamanaka, Takahiro; Miyazaki, Tatsuya; Kumakura, Yuji; Honjo, Hiroaki; Hara, Keigo; Yokobori, Takehiko; Sakai, Makoto; Sohda, Makoto; Kuwano, Hiroyuki

    2015-01-01

    We experienced two cases involving the simultaneous presence of cholelithiasis, hiatal hernia, and umbilical hernia. Both patients were female and overweight (body mass index of 25.0-29.9 kg/m(2)) and had a history of pregnancy and surgical treatment of cholelithiasis. Additionally, both patients had two of the three conditions of Saint's triad. Based on analysis of the pathogenesis of these two cases, we consider that these four diseases (Saint's triad and umbilical hernia) are associated with one another. Obesity is a common risk factor for both umbilical hernia and Saint's triad. Female sex, older age, and a history of pregnancy are common risk factors for umbilical hernia and two of the three conditions of Saint's triad. Thus, umbilical hernia may readily develop with Saint's triad. Knowledge of this coincidence is important in the clinical setting. The concomitant occurrence of Saint's triad and umbilical hernia may be another clinical "tetralogy."

  17. Measuring finite-range phase coherence in an optical lattice using Talbot interferometry

    PubMed Central

    Santra, Bodhaditya; Baals, Christian; Labouvie, Ralf; Bhattacherjee, Aranya B.; Pelster, Axel; Ott, Herwig

    2017-01-01

    One of the important goals of present research is to control and manipulate coherence in a broad variety of systems, such as semiconductor spintronics, biological photosynthetic systems, superconducting qubits and complex atomic networks. Over the past decades, interferometry of atoms and molecules has proven to be a powerful tool to explore coherence. Here we demonstrate a near-field interferometer based on the Talbot effect, which allows us to measure finite-range phase coherence of ultracold atoms in an optical lattice. We apply this interferometer to study the build-up of phase coherence after a quantum quench of a Bose–Einstein condensate residing in a one-dimensional optical lattice. Our technique of measuring finite-range phase coherence is generic, easy to adopt and can be applied in practically all lattice experiments without further modifications. PMID:28580941

  18. Michael Faraday's Bicentenary.

    ERIC Educational Resources Information Center

    Williams, L. Pearce; And Others

    1991-01-01

    Six articles discuss the work of Michael Faraday, a chemist whose work revolutionized physics and led directly to both classical field and relativity theory. The scientist as a young man, the electromagnetic experiments of Faraday, his search for the gravelectric effect, his work on optical glass, his laboratory notebooks, and his creative use of…

  19. Cadaveric and in vivo human joint imaging based on differential phase contrast by X-ray Talbot-Lau interferometry.

    PubMed

    Tanaka, Junji; Nagashima, Masabumi; Kido, Kazuhiro; Hoshino, Yoshihide; Kiyohara, Junko; Makifuchi, Chiho; Nishino, Satoshi; Nagatsuka, Sumiya; Momose, Atsushi

    2013-09-01

    We developed an X-ray phase imaging system based on Talbot-Lau interferometry and studied its feasibility for clinical diagnoses of joint diseases. The system consists of three X-ray gratings, a conventional X-ray tube, an object holder, an X-ray image sensor, and a computer for image processing. The joints of human cadavers and healthy volunteers were imaged, and the results indicated sufficient sensitivity to cartilage, suggesting medical significance. Copyright © 2012. Published by Elsevier GmbH.

  20. Goodbye Michael Gove

    ERIC Educational Resources Information Center

    Bassey, Michael

    2014-01-01

    Michael Gove was Secretary of State for Education from May 2010 to July 2014 when the Prime Minister sacked him. With strong opinions arising from his own life experiences and outstanding energy for reform, but severely limited understanding of education and a refusal to consult teachers and other professionals, he imposed half-baked ideas on the…

  1. Michael J. Meaney: Award for Distinguished Scientific Contributions

    ERIC Educational Resources Information Center

    American Psychologist, 2012

    2012-01-01

    Presents Michael J. Meaney as one of the winners of the American Psychological Association's Award for Distinguished Scientific Contributions (2012). Michael J. Meaney has taken the phenomenon of "handling" of newborn rats and opened a new area of investigation that has given new meaning to epigenetics via his work demonstrating transgenerational…

  2. The Saint Louis River Idea-Slam crowd sourcing good ideas for the Saint Louis River

    EPA Science Inventory

    As part of the 2017 Saint Louis River Summit, we propose hosting an “Idea-Slam” using software originally developed by the U.S. Consumer Financial Protection Bureau. Idea-box is an open source online app/website used to collect and surface ideas from members of an or...

  3. High precision locating control system based on VCM for Talbot lithography

    NASA Astrophysics Data System (ADS)

    Yao, Jingwei; Zhao, Lixin; Deng, Qian; Hu, Song

    2016-10-01

    Aiming at the high precision and efficiency requirements of Z-direction locating in Talbot lithography, a control system based on Voice Coil Motor (VCM) was designed. In this paper, we built a math model of VCM and its moving characteristic was analyzed. A double-closed loop control strategy including position loop and current loop were accomplished. The current loop was implemented by driver, in order to achieve the rapid follow of the system current. The position loop was completed by the digital signal processor (DSP) and the position feedback was achieved by high precision linear scales. Feed forward control and position feedback Proportion Integration Differentiation (PID) control were applied in order to compensate for dynamic lag and improve the response speed of the system. And the high precision and efficiency of the system were verified by simulation and experiments. The results demonstrated that the performance of Z-direction gantry was obviously improved, having high precision, quick responses, strong real-time and easily to expend for higher precision.

  4. Talbot phase-contrast X-ray imaging for the small joints of the hand

    PubMed Central

    Stutman, Dan; Beck, Thomas J; Carrino, John A; Bingham, Clifton O

    2011-01-01

    A high resolution radiographic method for soft tissues in the small joints of the hand would aid in the study and treatment of Rheumatoid Arthritis (RA) and Osteoarthritis (OA), which often attacks these joints. Of particular interest would be imaging with <100 μm resolution the joint cartilage, whose integrity is a main indicator of disease. Differential phase-contrast or refraction based X-ray imaging (DPC) with Talbot grating interferometers could provide such a method, since it enhances soft tissue contrast and it can be implemented with conventional X-ray tubes. A numerical joint phantom was first developed to assess the angular sensitivity and spectrum needed for a hand DPC system. The model predicts that due to quite similar refraction indexes for joint soft tissues, the refraction effects are very small, requiring high angular resolution. To compare our model to experiment we built a high resolution bench-top interferometer using 10 μm period gratings, a W anode tube and a CCD based detector. Imaging experiments on animal cartilage and on a human finger support the model predictions. For instance, the estimated difference between the index of refraction of cartilage and water is of only several percent at ~25 keV mean energy, comparable to that between the linear attenuation coefficients. The potential advantage of DPC imaging comes thus mainly from the edge enhancement at the soft tissue interfaces. Experiments using a cadaveric human finger are also qualitatively consistent with the joint model, showing that refraction contrast is dominated by tendon embedded in muscle, with the cartilage layer difficult to observe in our conditions. Nevertheless, the model predicts that a DPC radiographic system for the small hand joints of the hand could be feasible using a low energy quasi-monochromatic source, such as a K-edge filtered Rh or Mo tube, in conjunction with a ~2 m long ‘symmetric’ interferometer operated in a high Talbot order. PMID:21841214

  5. Talbot phase-contrast x-ray imaging for the small joints of the hand

    NASA Astrophysics Data System (ADS)

    Stutman, Dan; Beck, Thomas J.; Carrino, John A.; Bingham, Clifton O.

    2011-09-01

    A high-resolution radiographic method for soft tissues in the small joints of the hand would aid in the study and treatment of rheumatoid arthritis (RA) and osteoarthritis (OA), which often attacks these joints. Of particular interest would be imaging with <100 µm resolution the joint cartilage, whose integrity is a main indicator of disease. Differential phase-contrast (DPC) or refraction-based x-ray imaging with Talbot grating interferometers could provide such a method, since it enhances soft tissue contrast and can be implemented with conventional x-ray tubes. A numerical joint phantom was first developed to assess the angular sensitivity and spectrum needed for a hand DPC system. The model predicts that, due to quite similar refraction indexes for joint soft tissues, the refraction effects are very small, requiring high angular resolution. To compare our model to experiment we built a high-resolution bench-top interferometer using 10 µm period gratings, a W anode tube and a CCD-based detector. Imaging experiments on animal cartilage and on a human finger support the model predictions. For instance, the estimated difference between the index of refraction of cartilage and water is of only several percent at ~25 keV mean energy, comparable to that between the linear attenuation coefficients. The potential advantage of DPC imaging thus comes mainly from the edge enhancement at the soft tissue interfaces. Experiments using a cadaveric human finger are also qualitatively consistent with the joint model, showing that refraction contrast is dominated by tendon embedded in muscle, with the cartilage layer difficult to observe in our conditions. Nevertheless, the model predicts that a DPC radiographic system for the small hand joints of the hand could be feasible using a low energy quasi-monochromatic source, such as a K-edge filtered Rh or Mo tube, in conjunction with a ~2 m long 'symmetric' interferometer operated in a high Talbot order.

  6. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    NASA Administrator Dr. Michael Griffin speaks in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  7. The harmonious relationship between faith and science from the perspective of some great saints: A brief comment.

    PubMed

    Cortés, Manuel E; Del Río, Juan Pablo; Vigil, Pilar

    2015-02-01

    The objective of this editorial is to show that a harmonious relationship between science and faith is possible, as exemplified by great saints of the Catholic Church. It begins with the definitions of science and faith, followed by an explanation of the apparent conflict between them. A few saints that constitute an example that a fruitful relationship between these two seemingly opposed realities has been possible are Saint Albert the Great, Saint John of the Cross, Saint Giuseppe Moscati, and Saint Edith Stein, among others, and this editorial highlights their deep contributions to the dialogue between faith and reason. This editorial ends with a brief discussion on whether it is possible to be both a scientist and a man of faith.

  8. The harmonious relationship between faith and science from the perspective of some great saints: A brief comment

    PubMed Central

    Cortés, Manuel E.; del Río, Juan Pablo; Vigil, Pilar

    2015-01-01

    The objective of this editorial is to show that a harmonious relationship between science and faith is possible, as exemplified by great saints of the Catholic Church. It begins with the definitions of science and faith, followed by an explanation of the apparent conflict between them. A few saints that constitute an example that a fruitful relationship between these two seemingly opposed realities has been possible are Saint Albert the Great, Saint John of the Cross, Saint Giuseppe Moscati, and Saint Edith Stein, among others, and this editorial highlights their deep contributions to the dialogue between faith and reason. This editorial ends with a brief discussion on whether it is possible to be both a scientist and a man of faith. PMID:25698837

  9. 4. Photocopy of inkandwatercolor drawing (from St. Michael's Church) Rambusch, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopy of ink-and-watercolor drawing (from St. Michael's Church) Rambusch, illustrator ca. 1932-37 INTERIOR, LOOKING NORTHEAST - St. Michael's Catholic Church, 519 East Third Street, Madison, Jefferson County, IN

  10. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    NASA Administrator Dr. Michael Griffin is seen during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  11. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    NASA Administrator Dr. Michael Griffin smiles during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  12. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    NASA Administrator Dr. Michael Griffin delivers a statement during testimony in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  13. Doing It All: Michael Sullivan--Weeks Public Library, NH

    ERIC Educational Resources Information Center

    Library Journal, 2005

    2005-01-01

    Michael Sullivan is a juggler--not a metaphorical one, a real one. He's also a library director, storyteller, competitive chess player, poet, speaker, and former children's librarian who continues to work with the kids in his community. This article summarizes the accomplishments and work of Michael Sullivan.

  14. 76 FR 10352 - Keyser, Michael J.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-6495-000] Keyser, Michael J.; Notice of Filing Take notice that on February 15, 2011, Michael J. Keyser submitted for filing, an application for authority to hold interlocking positions, pursuant to section 305(b) of the...

  15. Language and Intercultural Education: An Interview with Michael Byram

    ERIC Educational Resources Information Center

    Porto, Melina

    2013-01-01

    This article reports an interview with Michael Byram, Professor Emeritus, University of Durham in the United Kingdom, during his visit to Argentina in September 2011. Michael Byram is one of the main international referents in intercultural education. The interview addresses issues such as language education, intercultural and citizenship…

  16. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    NASA Administrator Dr. Michael Griffin is seen prior to his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  17. Sanctified madness: the God-intoxicated saints of Bengal.

    PubMed

    Morinis, A

    1985-01-01

    The saintly madman is a familiar character in South Asia. To outer appearances he is no different from a lunatic, but the mad saint comes to be revered because his idiocy is popularly believed to arise from a different cause than ordinary madness. The common psychopath neglects social conventions because his consciousness is dimmed by incapacity; the saintly madman also breaches convention, but does so because his heightened consciousness has liberated him from the bonds of convention that entrap ordinary people. In the terms of Hinduism, he has tasted the divine nectar of God-realization and has returned to the human realm intoxicated by the experience. In this paper two popular God intoxicated saints of Bengal are discussed. The question is posed whether 'God intoxication' can be considered a culture-bound syndrome of Bengal. The concept of 'culture bound syndrome' is found to be too narrow to encompass the most significant issues to arise from reflection on the characteristics of the God intoxicated. These larger issues have to do with the relationship between cultural practices and models and mental states (whether deviant, as implied by the term 'syndrome' although deviance does not always carry the negative connotation implicit in 'syndrome', or normal). It is suggested that all cultures culture a limited range of mental states and thus the questions posed by the notion of culture bound syndromes are subsumed by larger questions about the relationship of all mind-states to the socio-cultural environment which conditions them. The conclusion is that God intoxication is indeed a uniquely Bengali mental condition, with variants throughout South Asia and kinship to other mystical states, but that the concept of 'syndrome' is not useful.

  18. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    Senator Trent Lott, R-Miss., questions NASA Administrator Dr. Michael Griffin during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  19. Michael Faraday vs. the Spiritualists

    NASA Astrophysics Data System (ADS)

    Hirshfeld, Alan

    2006-12-01

    In the 1850s, renowned physicist Michael Faraday launched a public campaign against pseudoscience and spiritualism, which were rampant in England at the time. Faraday objected especially to claims that electrical or magnetic forces were responsible for paranormal phenomena, such as table-spinning and communication with the dead. Using scientific methods, Faraday unmasked the deceptions of spiritualists, clairvoyants and mediums and also laid bare the credulity of a public ill-educated in science. Despite his efforts, Victorian society's fascination with the paranormal swelled. Faraday's debacle anticipates current controversies about public science education and the interface between science and religion. This episode is one of many described in the new biography, The Electric Life of Michael Faraday (Walker & Co.), which chronicles Faraday's discoveries and his unlikely rise from poverty to the pinnacle of the English science establishment.

  20. Q&A: Michael Honey

    ERIC Educational Resources Information Center

    Helicher, Karl

    2007-01-01

    The mid-1960s saw civil rights victories in Congress during Lyndon B. Johnson's presidency. In "Going Down Jericho Road," Michael Honey wrote how Martin Luther King Jr.'s final focus showed that the struggle for black and working class parity continued. The 1968 Memphis sanitation workers strike was a gritty struggle won in the streets by a host…

  1. Michael Griffin Senate Hearing

    NASA Image and Video Library

    2005-05-17

    U.S. Senator Bill Nelson. R-Fla., questions NASA Administrator Dr. Michael Griffin during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

  2. Michael Young and the Curriculum Field in South Africa

    ERIC Educational Resources Information Center

    Hoadley, Ursula

    2015-01-01

    The paper addresses the question of what we should make of Michael Young's recent work with respect to curriculum theory by considering the particular case of South African curriculum reform. The paper thus traces two trajectories: the evolution of Michael Young's ideas over time and South African curriculum reform in the post-apartheid period.…

  3. Michael Griffin Oath Of Office

    NASA Image and Video Library

    2005-04-14

    John H. Marburger, Science Adviser to the President and Director of the Office of Science and Technology Policy (OSTP), left, shakes hands with NASA Administrator Michael Griffin following his swearing-in, Thursday, April 14, 2005, in Washington. Photo Credit: (NASA/Renee Bouchard)

  4. Prayer to the Saints or the Virgin And Health Among Older Mexican Americans

    PubMed Central

    Krause, Neal; Bastida, Elena

    2011-01-01

    The purpose of this study was to evaluate a conceptual model that assesses whether praying to the saints or the Virgin is associated with the health of older Mexican Americans. A survey was conducted of 1,005 older Mexican Americans (Mean age = 73.9 years; SD = 6.6 years). Data from 795 of the Catholic respondents are presented in this study. The findings support the following relationships that are embedded in the conceptual model: (1) older Mexican Americans who attend church more often are more likely to believe in the efficacy of prayer to the saints or the Virgin; (2) stronger beliefs in the efficacy of intercessory prayer are associated with more frequent prayer to the saints or the Virgin; (3) frequent prayer is to the saints or the Virgin is associated with greater God-mediated control beliefs; (4) stronger God-mediated control beliefs are associated with greater optimism; and (5) greater optimism is associated with better self-rated health. PMID:21415935

  5. Michael Griffin House Science Committee Hearing

    NASA Image and Video Library

    2005-06-27

    NASA Administrator Michael Griffin prepares to testify at a hearing before the House Science Committee, Tuesday, June 28, 2005, Rayburn House Office building, Washington. Photo Credit: (NASA/Bill Ingalls)

  6. Evidence supporting an intentional Neandertal burial at La Chapelle-aux-Saints.

    PubMed

    Rendu, William; Beauval, Cédric; Crevecoeur, Isabelle; Bayle, Priscilla; Balzeau, Antoine; Bismuth, Thierry; Bourguignon, Laurence; Delfour, Géraldine; Faivre, Jean-Philippe; Lacrampe-Cuyaubère, François; Tavormina, Carlotta; Todisco, Dominique; Turq, Alain; Maureille, Bruno

    2014-01-07

    The bouffia Bonneval at La Chapelle-aux-Saints is well known for the discovery of the first secure Neandertal burial in the early 20th century. However, the intentionality of the burial remains an issue of some debate. Here, we present the results of a 12-y fieldwork project, along with a taphonomic analysis of the human remains, designed to assess the funerary context of the La Chapelle-aux-Saints Neandertal. We have established the anthropogenic nature of the burial pit and underlined the taphonomic evidence of a rapid burial of the body. These multiple lines of evidence support the hypothesis of an intentional burial. Finally, the discovery of skeletal elements belonging to the original La Chapelle aux Saints 1 individual, two additional young individuals, and a second adult in the bouffia Bonneval highlights a more complex site-formation history than previously proposed.

  7. Michael Tomasello: Award for Distinguished Scientific Contributions.

    PubMed

    2015-11-01

    The APA Awards for Distinguished Scientific Contributions are presented to persons who, in the opinion of the Committee on Scientific Awards, have made distinguished theoretical or empirical contributions to basic research in psychology. One of the 2015 award winners is Michael Tomasello, who received this award for "outstanding empirical and theoretical contributions to understanding what makes the human mind unique. Michael Tomasello's pioneering research on the origins of social cognition has led to revolutionary insights in both developmental psychology and primate cognition." Tomasello's award citation, biography, and a selected bibliography are presented here. (c) 2015 APA, all rights reserved).

  8. Michael Griffin House Science Committee Hearing

    NASA Image and Video Library

    2005-06-27

    Rep. Bart Gordon, D-TN., questions NASA Administrator Michael Griffin during a House Science Committee hearing, Tuesday, June 28, 2005, Rayburn House Office building, Washington. Photo Credit: (NASA/Bill Ingalls)

  9. ASK Talks with Dr. Michael Hecht

    NASA Technical Reports Server (NTRS)

    Hecht, Michael

    2003-01-01

    Michael Hecht has been a member of NASA's Jet Propulsion Laboratory (JPL) staff since 1982. He is currently Project Manager and co-investigator for the Mars Environmental Compatibility Assessment (MECA)

  10. Michael Thackeray on Lithium-air Batteries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thackeray, Michael

    2009-01-01

    Michael Thackeray, Distinguished Fellow at Argonne National Laboratory, speaks on the new technology Lithium-air batteries, which could potentially increase energy density by 5-10 times over lithium-ion batteries.

  11. Michael Thackeray on Lithium-air Batteries

    ScienceCinema

    Thackeray, Michael

    2018-02-06

    Michael Thackeray, Distinguished Fellow at Argonne National Laboratory, speaks on the new technology Lithium-air batteries, which could potentially increase energy density by 5-10 times over lithium-ion batteries.

  12. Following Michael Faraday's Footprints

    ERIC Educational Resources Information Center

    Galeano, Javier

    2011-01-01

    Last fall I had the good fortune of receiving financial support to shoot a documentary about Michael Faraday. I took the opportunity to learn more about this great experimentalist and to visit the highlights of places in his life. In this paper, I would like to share a list and description of some of the most remarkable places in London suitable…

  13. The Michael Reaction

    NASA Astrophysics Data System (ADS)

    Poon, Thomas; Mundy, Bradford P.; Shattuck, Thomas W.

    2002-02-01

    A brief account of the Michael reaction is provided, illustrating its versatility as a topic in undergraduate chemistry courses. Included is a short biography of the reaction's namesake, examples of its use in organic synthesis, and its unique role in the defense mechanism of the bacterium Micromonospora echinospora. A computational rationale for the selectivity of 1,4 versus 1,2 addition of nucleophiles to a,b-unsaturated carbonyls is discussed and links to animations suitable for an introductory organic chemistry course are provided.

  14. Catalytic asymmetric Michael reactions promoted by a lithium-free lanthanum-BINOL complex

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sasai, Hiroaki; Arai, Takayoshi; Shibasaki, Masakatsu

    1994-02-23

    In this communication, we report about a new lithium-free BINOL-lanthanum complex, which is quite effective in catalytic asymmetric Michael reaction. We have succeeded in developing effective asymmetric base catalysts, in particular, asymmetric ester enolate catalysts for asymmetric Michael reactions. Two asymmetric lanthanum complexes are now available, namely, BINOL-lanthanum-lithium complex, which is quite effective in catalytic asymmetric nitrosaldol reactions, and a new lithium-free BINOL-lanthanum ester enolate complex, that is very effective in catalytic asymmetric Michael reactions. The two complexes complement each other in their ability to catalyze asymmetric nitroaldol and asymmetric Michael reactions. 14 refs., 1 fig., 2 tabs.

  15. Michael Griffin House Science Committee Hearing

    NASA Image and Video Library

    2005-06-27

    Members of the media photograph NASA Administrator Michael Griffin as he testifies at a hearing before the House Science Committee, Tuesday, June 28, 2005, Rayburn House Office building, Washington. Photo Credit: (NASA/Bill Ingalls)

  16. Obituary: Michael James Ledlow, 1964-2004

    NASA Astrophysics Data System (ADS)

    Puxley, Philip John; Grashuis, Randon M.

    2004-12-01

    Michael James Ledlow died on 5 June 2004 from a large, unsuspected brain tumor. Since 2000 he had been on the scientific staff of the Gemini Observatory in La Serena, Chile, initially as a Science Fellow and then as a tenure-track astronomer. Michael was born in Bartlesville, Oklahoma on 1 October 1964 to Jerry and Sharon Ledlow. He obtained his Bachelor Degree in astrophysics at the University of Oklahoma in 1987 and attended the University of New Mexico for his graduate work, obtaining his PhD while studying Galaxy Clusters under Frazer Owen in 1994. From 1995-1997 Michael held a postdoctoral position with Jack Burns at New Mexico State University where he used various astronomical facilities including the VLA and Apache Point Observatory to study distant galaxies. From 1998-2000 Michael rejoined the Physics and Astronomy Department at the University of New Mexico where he was a visiting professor until he moved on to Gemini. At the Gemini Observatory, Mike shared in the excitement, hard work and many long days and nights associated with bringing on-line a major new astronomical facility and its instrumentation. Following its commissioning he assisted visiting observers, supported and took data for many more remote users via the queue system, and for each he showed the same care and attention to detail evident in his own research to ensure that all got the best possible data. His research concentrated on the radio and optical properties of galaxy clusters, especially rich Abell clusters such as A2125, on luminous radio galaxies, including the detection of a powerful double radio source in the "wrong sort of galaxy," the spiral system 0313-192, and on EROs (extremely red objects), dusty galaxies barely detectable at optical wavelengths. Michael thoroughly enjoyed living in Chile and enthusiastically immersed himself in the culture of his surroundings. He and his family were actively involved with the International English Spanish Association in La Serena. He had a

  17. NASA Catches Tropical Storm Leslie and Hurricane Michael in the Atlantic

    NASA Image and Video Library

    2017-12-08

    This visible image of Tropical Storm Leslie and Hurricane Michael was taken by the MODIS instrument aboard both NASA's Aqua and Terra satellites on Sept. 9 at 12:50 p.m. EDT. Credit: NASA Goddard/MODIS Rapid Response Team -- Satellite images from two NASA satellites were combined to create a full picture of Tropical Storm Leslie and Hurricane Michael spinning in the Atlantic Ocean. Imagery from NASA's Aqua and Terra satellites showed Leslie now past Bermuda and Michael in the north central Atlantic, and Leslie is much larger than the smaller, more powerful Michael. Images of each storm were taken by the Moderate Resolution Imaging Spectroradiometer, or MODIS instrument that flies onboard both the Aqua and Terra satellites. Both satellites captured images of both storms on Sept. 7 and Sept. 10. The image from Sept. 7 showed a much more compact Michael with a visible eye. By Sept. 10, the eye was no longer visible in Michael and the storm appeared more elongated from south to north. To continue reading go to: 1.usa.gov/NkUPqn NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  18. Interview with Michael Apple: The Biography of a Public Intellectual

    ERIC Educational Resources Information Center

    Peters, Michael A.

    2015-01-01

    Michael W. Apple is the John Bascom Professor of Curriculum and Instruction and Educational Policy Studies in the Departments of Curriculum and Instruction (CI) and Educational Policy Studies (EPS) at the University of Wisconsin-Madison School of Education where he has taught since 1970. Michael Apple is one of the foremost educational theorists…

  19. Michael Griffin Oath Of Office

    NASA Image and Video Library

    2005-04-14

    John H. Marburger, Science Adviser to the President and Director of the Office of Science and Technology Policy (OSTP), left, talks with NASA Administrator Michael Griffin, center, while his wife Rebecca and daughter Katie look on following his swearing-in, Thursday, April 14, 2005, in Washington. Photo Credit: (NASA/Renee Bouchard)

  20. Michael Beitz: Objects of Communication

    ERIC Educational Resources Information Center

    Hoefferle, Mary

    2014-01-01

    For this Instructional Resource, the author interviewed contemporary sculptor Michael Beitz, who uses art to explore the role of designed objects in human communication and emotional experience. This column was written in response to calls for using Enduring Understandings/Big Ideas (National Coalition for Core Arts Standards, 2013; Stewart &…

  1. Michael Faraday, media man.

    PubMed

    Fara, Patricia

    2006-03-01

    Michael Faraday was an enthusiastic portrait collector, and he welcomed the invention of photography not only as a possible means of recording observations accurately, but also as a method for advertising science and its practitioners. This article (which is part of the Science in the Industrial Revolution series) shows that like many eminent scientists, Faraday took advantage of the burgeoning Victorian media industry by posing in various roles.

  2. Synthesis of Triazole Derivatives of Levoglucosenone As Promising Anticancer Agents: Effective Exploration of the Chemical Space through retro-aza-Michael//aza-Michael Isomerizations.

    PubMed

    Tsai, Yi-Hsuan; Borini Etichetti, Carla M; Di Benedetto, Carolina; Girardini, Javier E; Martins, Felipe Terra; Spanevello, Rolando A; Suárez, Alejandra G; Sarotti, Ariel M

    2018-04-06

    The design and synthesis of biomass-derived triazoles and the in vitro evaluation as potential anticancer agents are described. The discovery of base-catalyzed retro-aza-Michael//aza-Michael isomerizations allowed the exploration of the chemical space by affording novel types of triazoles, difficult to obtain otherwise. Following this strategy, 2,4-disubstituted 1,2,3-triazoles could be efficiently obtained from the corresponding 1,4-disubstituted analogues.

  3. The Obscurantist Design in Saint Augustine's Rhetoric.

    ERIC Educational Resources Information Center

    Wiethoff, William E.

    This paper examines Saint Augustine's obscurantist preferences in popular preaching (as distinguished from his episcopal instructions to other clergy) as a way of identifying one of the classical influences on Christian rhetorical strategy. The first section of the paper offers a comparison of Augustine's theoretical approval of homiletic…

  4. The Relationship between Proficiency in French and Academic Achievement for Students in Saint Martin

    ERIC Educational Resources Information Center

    Wilson, Martin Ezikiel

    2013-01-01

    School administrators and educational policy makers have made a substantial effort to address the learning needs of students in Saint Martin, yet the achievement gap between students in Saint Martin and students in metropolitan France still persists. Risk factors such as family structure, socioeconomic status, immigration, and difficulty of…

  5. Microseismic noise in the Saint Peter and Saint Paul Archipelago, equatorial Atlantic

    NASA Astrophysics Data System (ADS)

    de Queiroz, Daniel É.; do Nascimento, Aderson F.; Schimmel, Martin

    2017-12-01

    Microseismic noise, also known as ambient seismic noise, are continuous vibrations mostly composed of Rayleigh waves pervasively recorded in the mili Hertz to 1 Hz frequency range. Their precise source mechanisms are under investigations and related to atmospheric perturbations and ocean gravity waves. Our purpose is to show the behavior of the microseismic noise recorded in the Saint Peter and Saint Paul Archipelago (SPSPA) with respect to wind intensity and ocean waves height in this region, between the North and South Atlantic Ocean. We have recorded both primary microseisms (PM) 0.04-0.12 Hz and the secondary microseisms (SM) 0.12-0.4 Hz during almost four years (2012-2015) and we used frequency, temporal, spatial and statistical correlation analysis to do qualitative and quantitative analysis with respect to wind speed intensity and significant wave height for the same periods. The results indicate a good correlation between the PM and the SM noise in the region particularly during the winter in the Northern Hemisphere and a poor correlation during the summer. We have also shown that probably most of the PM are generated in the SPSPA itself. We note that the intensity of SM recorded in SPSPA appears to have a seasonal behavior with the summer and winter in the Northern Hemisphere, and seems to influence the correlation between the PM and the SM, suggesting that the sources of the PM and the SM are not related to the same atmospheric event and from different places. PM generation would occur near the SPSPA whilst the SM would have distant sources towards the North Atlantic.

  6. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    Dr. Michael Griffin testifies, Tuesday, April 12, 2005, during his confirmation hearing before the U.S. Senate Commerce Committee at the Russell Senate Office Building in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit (NASA/Renee Bouchard)

  7. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-11

    Dr. Michael Griffin testifies, Tuesday, April 12, 2005, during his confirmation hearing before the U.S. Senate Commerce Committee at the Russell Senate Office Building in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit (NASA/Renee Bouchard)

  8. Single-shot Z(eff) dense plasma diagnostic through simultaneous refraction and attenuation measurements with a Talbot-Lau x-ray moiré deflectometer.

    PubMed

    Valdivia, M P; Stutman, D; Finkenthal, M

    2015-04-01

    The Talbot-Lau x-ray moiré deflectometer is a powerful plasma diagnostic capable of delivering simultaneous refraction and attenuation information through the accurate detection of x-ray phase shift and intensity. The diagnostic can provide the index of refraction n=1-δ+iβ of an object (dense plasma, for example) placed in the x-ray beam by independently measuring both δ and β, which are directly related to the electron density n(e) and the attenuation coefficient μ, respectively. Since δ and β depend on the effective atomic number Z(eff), a map can be obtained from the ratio between phase and absorption images acquired in a single shot. The Talbot-Lau x-ray moiré deflectometer and its corresponding data acquisition and processing are briefly described to illustrate how the above is achieved; Z(eff) values of test objects within the 4-12 range were obtained experimentally through simultaneous refraction and attenuation measurements. We show that Z(eff) mapping of objects does not require previous knowledge of sample length or shape. The determination of Z(eff) from refraction and attenuation measurements with moiré deflectometry could be of high interest to various domains of high energy density research, such as shocked materials and inertial confinement fusion experiments, as well as material science and nondestructive testing.

  9. Michael Akam and the rise of evolutionary developmental biology

    PubMed Central

    Stern, David L.; Dawes-Hoang, Rachel E.

    2010-01-01

    Michael Akam has been awarded the 2007 Kowalevsky medal for his many research accomplishments in the area of evolutionary developmental biology. We highlight three tributaries of Michael’s contribution to evolutionary developmental biology. First, he has made major contributions to our understanding of development of the fruit fly, Drosophila melanogaster. Second, he has maintained a consistent focus on several key problems in evolutionary developmental biology, including the evolving role of Hox genes in arthropods and, more recently, the evolution of segmentation mechanisms. Third, Michael has written a series of influential reviews that have integrated progress in developmental biology into an evolutionary perspective. Michael has also made a large impact on the field through his effective mentorship style, his selfless promotion of younger colleagues, and his leadership of the University Museum of Zoology at Cambridge and the European community of evolutionary developmental biologists. PMID:20209429

  10. Michael Griffin Oath Of Office

    NASA Image and Video Library

    2005-04-14

    NASA Administrator Michael Griffin, left, is administered the oath of office by John H. Marburger, right, Science Adviser to the President and Office of Science and Technology Policy Director, during a private ceremony at the Old Executive Office Building, Thursday, April 14, 2005, in Washington, while his wife Rebecca and daughter Katie look on. Photo Credit: (NASA/Renee Bouchard)

  11. Biology of Grapsus grapsus (L innaeus, 1758) (Brachyura, Grapsidae) in the Saint Peter and Saint Paul Archipelago, Equatorial Atlantic Ocean

    NASA Astrophysics Data System (ADS)

    Freire, A. S.; Pinheiro, M. A. A.; Karam-Silva, H.; Teschima, M. M.

    2011-09-01

    Eleven expeditions were undertaken to the Saint Peter and Saint Paul Archipelago to study the reproductive biology of Grapsus grapsus, providing additional information on limb mutilation and carapace colour. MATURE software was used to estimate morphological maturity, while gonadal analyses were conducted to estimate physiological maturity. The puberty moult took place at larger size in males (51.4 mm of carapace length) than in females (33.8 mm), while physiological maturity occurred at a similar size in males (38.4 mm) and in females (33.4 mm). Above 50 mm, the proportion of red males increased in the population, indicating that functional maturity is also related to colour pattern. Small habitat and high local population density contributed to the high rate of cannibalism. The low diversity of food items, absence of predators of large crabs and high geographic isolation are the determinants of unique behavioural and biological characteristics observed in the G. grapsus population.

  12. The Saint Mary's Woman: toward Intellectual Leadership.

    ERIC Educational Resources Information Center

    White, Patrick E.

    This two-year project at Saint Mary's College, a women's college in Notre Dame (Indiana), focused on building intellectual community and fostering student leadership skills. The study targeted two student groups: (1) students with much to contribute to the intellectual life of the college but alienated from traditional forms of leadership, and (2)…

  13. Markets, Marx, Modernity and Mathematics Education: A Response to Michael Apple.

    ERIC Educational Resources Information Center

    Gates, Peter

    This paper is a response to Michael Apple's paper, "What Postmodernists Forget: Cultural Capital and Official Knowledge." The paper advocates Michael's identification of the current dangers and processes of the growth of new right ideologies in the development of subjectivity, society, and education. The differences in success in the education…

  14. Michael Griffin Meets with Elon Musk

    NASA Image and Video Library

    2005-04-19

    NASA Administrator Michael Griffin, left, meets with CEO of SpaceX Elon Musk, right, Wednesday, April 20, 2005 at NASA Headquarters in Washington. Looking on in the background are Larry Williams, NASA astronaut Marsha Ivins and NASA manager Christopher Shank. Photo Credit: (NASA/Renee Bouchard)

  15. Michael Sadler and the German Connection.

    ERIC Educational Resources Information Center

    Higginson, J. H.

    1990-01-01

    Chronicles works of Michael Sadler who compared British and German educational systems, emphasizing Germany's contributions in technical education. Presents Sadler's 1912 recommendations--eight lessons premised upon powerful centralized government's ability to implement policy. Reflects on how World War I and Nazism influenced Sadler's thought and…

  16. [A short history of René Groupil, patron saint of anesthetists].

    PubMed

    Quintal, J

    1994-10-01

    Born in 1608 near Angers, France, René Goupil looked after the native people at Sillery, Québec between 1640 and 1642 as surgeon and donné. Ambushed and captured by Mohawk warriors, he was killed in September 1642 near Auriesville NY. He was canonized in 1930. The life of Goupil is reviewed with regards to primitive medicine of the 17th century. In 1951, american nurse anesthetists chose René Goupil, health worker and saint of North America, as the patron saint of the anaesthetists. Since, he has been recognized by more and more practitioners of anaesthesia.

  17. Michael Polanyi: Science as Personal Knowledge and Social Practice.

    PubMed

    Nye, Mary Jo

    2017-03-20

    Tacit knowing: 2016 marked the 125th anniversary of the birth of the physical chemist Michael Polanyi, as well as the 40th of his death. This essay discusses his philosophy of science-in particular, his most significant work in this area, Personal Knowledge-from the perspective of his personal biography, as well as its lasting influence on the social sciences. In the photograph: Michael Polanyi at the Fritz Haber Institute in 1968. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Overview of environmental and hydrogeologic conditions at Saint Marys, Alaska

    USGS Publications Warehouse

    Nakanishi, Allan S.; Dorava, Joseph M.

    1994-01-01

    The Federal Aviation Administration (FAA) owns or operates airway support facilities near Saint Marys along the Yukon River in west-central Alaska. The FAA is evaluating the severity of environmental contamination and options for remediation of environmental contamination at their facilities. Saint Marys is on a flood plain near the continence of the Yukon and Andreafsky Rivers and has long cold winters and short summers. Residents obtain their drinking water from an infiltration gallery fed by a creek near the village. Surface spills and disposal of hazardous materials combined with potential flooding may affect the quality of the surface and ground water. Alternative drinking-water sources are available, but would likely cost more than existing supplies to develop.

  19. Asymmetric Michael Addition Mediated by Chiral Ionic Liquids.

    PubMed

    Suzuki, Yumiko

    2018-06-01

    Chiral ionic liquids with a focus on their applications in asymmetric Michael additions and related reactions were reviewed. The examples were classified on the basis of the mode of asymmetric induction (e.g., external induction/non-covalent interaction or internal induction/covalent bond formation), the roles in reactions (as a solvent or catalyst), and their structural features (e.g., imidazolium-based chiral cations, other chiral oniums; proline derivatives). Most of the reactions with high chiral induction are Michael addition of ketones or aldehydes to chalcones or nitrostyrenes where proline-derived chiral ionic liquids catalyze the reaction through enamine/ iminium formation. Many reports demonstrate the recyclability of ionic liquid-tagged pyrrolidines.

  20. Saint Petersburg magnetic observatory: from Voeikovo subdivision to INTERMAGNET certification

    NASA Astrophysics Data System (ADS)

    Sidorov, Roman; Soloviev, Anatoly; Krasnoperov, Roman; Kudin, Dmitry; Grudnev, Andrei; Kopytenko, Yury; Kotikov, Andrei; Sergushin, Pavel

    2017-11-01

    Since June 2012 the Saint Petersburg magnetic observatory is being developed and maintained by two institutions of the Russian Academy of Sciences (RAS) - the Geophysical Center of RAS (GC RAS) and the Saint Petersburg branch of the Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of RAS (IZMIRAN SPb). On 29 April 2016 the application of the Saint Petersburg observatory (IAGA code SPG) for introduction into the INTERMAGNET network was accepted after approval by the experts of the first definitive dataset over 2015, produced by the GC RAS, and on 9 June 2016 the SPG observatory was officially certified. One of the oldest series of magnetic observations, originating in 1834, was resumed in the 21st century, meeting the highest quality standards and all modern technical requirements. In this paper a brief historical and scientific background of the SPG observatory foundation and development is given, the stages of its renovation and upgrade in the 21st century are described, and information on its current state is provided. The first results of the observatory functioning are discussed and geomagnetic variations registered at the SPG observatory are assessed and compared with geomagnetic data from the INTERMAGNET observatories located in the same region.

  1. An x-ray backlit Talbot-Lau deflectometer for high-energy-density electron density diagnostics.

    PubMed

    Valdivia, M P; Stutman, D; Stoeckl, C; Theobald, W; Mileham, C; Begishev, I A; Bromage, J; Regan, S P

    2016-02-01

    X-ray phase-contrast techniques can measure electron density gradients in high-energy-density plasmas through refraction induced phase shifts. An 8 keV Talbot-Lau interferometer consisting of free standing ultrathin gratings was deployed at an ultra-short, high-intensity laser system using K-shell emission from a 1-30 J, 8 ps laser pulse focused on thin Cu foil targets. Grating survival was demonstrated for 30 J, 8 ps laser pulses. The first x-ray deflectometry images obtained under laser backlighting showed up to 25% image contrast and thus enabled detection of electron areal density gradients with a maximum value of 8.1 ± 0.5 × 10(23) cm(-3) in a low-Z millimeter sized sample. An electron density profile was obtained from refraction measurements with an error of <8%. The 50 ± 15 μm spatial resolution achieved across the full field of view was found to be limited by the x-ray source-size, similar to conventional radiography.

  2. Noiseless intensity amplification of repetitive signals by coherent addition using the temporal Talbot effect

    PubMed Central

    Maram, Reza; Van Howe, James; Li, Ming; Azaña, José

    2014-01-01

    Amplification of signal intensity is essential for initiating physical processes, diagnostics, sensing, communications and measurement. During traditional amplification, the signal is amplified by multiplying the signal carriers through an active gain process, requiring the use of an external power source. In addition, the signal is degraded by noise and distortions that typically accompany active gain processes. We show noiseless intensity amplification of repetitive optical pulse waveforms with gain from 2 to ~20 without using active gain. The proposed method uses a dispersion-induced temporal self-imaging (Talbot) effect to redistribute and coherently accumulate energy of the original repetitive waveforms into fewer replica waveforms. In addition, we show how our passive amplifier performs a real-time average of the wave-train to reduce its original noise fluctuation, as well as enhances the extinction ratio of pulses to stand above the noise floor. Our technique is applicable to repetitive waveforms in any spectral region or wave system. PMID:25319207

  3. Michael Fisher at King's College London

    NASA Astrophysics Data System (ADS)

    Domb, Cyril

    1991-09-01

    Michael Fisher spent the first 16 years of his academic life in the Physics Department of King's College, London, starting as an undergraduate and ending as a full professor. A survey is undertaken of his activities and achievements during the various periods of this phase of his career.

  4. Michael Fisher at King's College London

    NASA Astrophysics Data System (ADS)

    Domb, Cyril

    Michael Fisher spent the first 16 years of his academic life in the Physics Department of King's College, London, starting as an undergraduate and ending as a full professor. A survey is undertaken of his activities and achievements during the various periods of this phase of his career.

  5. Thinking with the saint: the miracle of Saint Januarius of Naples and science in early modern Europe.

    PubMed

    de Ceglia, Francesco Paolo

    2014-01-01

    The aim of this paper is to reconstruct the way in which early modem science questioned and indirectly influenced (while being in its turn influenced by) the conceptualization of the liquefaction of the blood of Saint Januarius, a phenomenon that has been taking place at regular intervals in Naples since the late Middle Ages. In the seventeenth century, a debate arose that divided Europe between supporters of a theory of divine intervention and believers in the occult properties of the blood. These two theoretical options reflected two different perspectives on the relationship between the natural and the supernatural. While in the seventeenth century, the emphasis was placed on the predictable periodicity of the miraculous event of liquefaction as a manifestation of God in his role as a divine regulator, in the eighteenth century the event came to be described as capricious and unpredictable, in an attempt to differentiate miracles from the workings of nature, which were deemed to be normative. The miracle of the blood of Saint Januarius thus provides a window through which we can catch a glimpse of how the natural order was perceived in early modern Europe at a time when the Continent was culturally fragmented into north and south, Protestantism and Catholicism, learned and ignorant.

  6. 3-D Perspective View, Miquelon and Saint Pierre Islands

    NASA Image and Video Library

    2000-03-16

    This image shows Miquelon and Saint Pierre Islands, located south of Newfoundland, Canada. These islands, along with five smaller islands, are a self-governing territory of France. North is in the top right corner of the image.

  7. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    Dr. Michael Griffin, right, talks with his wife Rebecca Griffin prior to testifying at his confirmation hearing before the U.S. Senate Commerce Committee, Tuesday, April 12, 2005, at the Russell Senate Office Building in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit (NASA/Renee Bouchard)

  8. Virological Surveillance of Dengue in Saint Martin and Saint Barthélemy, French West Indies, Using Blood Samples on Filter Paper

    PubMed Central

    Matheus, Séverine; Chappert, Jean-Loup; Cassadou, Sylvie; Berger, Franck; Labeau, Bhetty; Bremand, Laetitia; Winicki, Alain; Huc-Anais, Patricia; Quenel, Philippe; Dussart, Philippe

    2012-01-01

    To strengthen active dengue surveillance in Saint Martin and Saint Barthélemy, two French Caribbean islands, we evaluated the epidemiological usefulness of collecting blood samples from NS1-positive dengue patients on filter paper to identify the dengue serotypes circulating in these regions during a 27-month period. This approach allowed dengue serotypes to be identified by reverse transcriptase-polymerase chain reaction in 90.1% of the total set of 666 samples analyzed and, in 95.5% of the samples collected during the acute phase of the disease. This prospective virological surveillance using blood samples absorbed onto filter paper, which were stored at 4°C and shipped at ambient temperature to a specialized laboratory for analysis, allowed us to avoid the logistic and financial costs associated with shipping frozen venous blood samples. This surveillance system offers a low-cost alternative for reinforcing dengue prevention in areas where specialized laboratories do not exist, notably by facilitating the early detection of potentially new dengue serotypes. PMID:22232467

  9. 75 FR 22436 - Michael Williams-Control Exemption-St. Maries River Railroad, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35365] Michael Williams-Control Exemption-St. Maries River Railroad, Inc. Michael Williams (applicant),\\1\\ a noncarrier, has filed a verified notice of exemption to acquire control of St. Maries River Railroad, Inc. (STMA), a Class...

  10. Meet EPA Scientist Michael Nye, Ph.D.

    EPA Pesticide Factsheets

    Michael Nye, Ph.D., is a social scientist who studies natural risk, socio-demographic change and sustainable behavior. Prior to joining EPA, he worked for the UK Environment Agency in flood risk management and emergency preparedness

  11. Comments on Michael (1993): Establishing Operations

    ERIC Educational Resources Information Center

    Moore, J.

    2013-01-01

    The present comments concern Michael's concept of motivative variables, and the implications of that concept for our understanding of the nature of reinforcement as well as the extinction of responses maintained through positive and negative reinforcement. We note that both extinction and altering motivative variables decrease responding, but…

  12. Studying Teachers and Schools: Michael Pressley's Legacy and Directions for Future Research

    ERIC Educational Resources Information Center

    Mohan, Lindsey; Lundeberg, Mary A.; Reffitt, Kelly

    2008-01-01

    Much of Michael Pressley's work during the past decade focused on the nature of highly effective, engaging literacy instruction. Michael Pressley believed that studying effective teachers and schools had the potential to influence more engaging and effective teaching, especially in underresourced schools. First, we describe the grounded…

  13. Asymmetric Michael Addition Mediated by Chiral Ionic Liquids

    PubMed Central

    Suzuki, Yumiko

    2018-01-01

    Chiral ionic liquids with a focus on their applications in asymmetric Michael additions and related reactions were reviewed. The examples were classified on the basis of the mode of asymmetric induction (e.g., external induction/non-covalent interaction or internal induction/covalent bond formation), the roles in reactions (as a solvent or catalyst), and their structural features (e.g., imidazolium-based chiral cations, other chiral oniums; proline derivatives). Most of the reactions with high chiral induction are Michael addition of ketones or aldehydes to chalcones or nitrostyrenes where proline-derived chiral ionic liquids catalyze the reaction through enamine/ iminium formation. Many reports demonstrate the recyclability of ionic liquid-tagged pyrrolidines. PMID:29861702

  14. Michael Slote and "Sentimentalist Moral Education"

    ERIC Educational Resources Information Center

    Wren, Thomas

    2010-01-01

    Although I think most of what Michael Slote asserts in his article "Sentimentalist moral education" is correct, I worry about three important ideas that are conspicuous by their absence. The first is the possibility that human emotions and feelings are inherently cognitive, which is never considered in his psychological account of empathy. The…

  15. 77 FR 61596 - Wheatley, Michael I.; Garrison, Drummond E.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ...] Wheatley, Michael I.; Garrison, Drummond E.; Notice of Filing Take notice that on September 28, 2012, Michael I. Wheatley and Drummond E. Garrison submitted for filing, an application for authority to hold... the ``eFiling'' link at http://www.ferc.gov . Persons unable to file electronically should submit an...

  16. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    U.S. Senator Daniel K. Inouye, D-Hawaii, left, speaks as U.S. Senator Ted Stevens, R-Alaska, looks on during the confirmation hearing for Dr. Michael Griffin, in front of the U.S. Senate Commerce Committee, Tuesday, April 12, 2005, in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit (NASA/Renee Bouchard)

  17. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    U.S. Senator Barbara Mikulski, D-Md., testifies before the U.S. Senate Commerce Committee during the confirmation hearing of Dr. Michael Griffin, rear center, Tuesday, April 12, 2005, at the Russell Senate Office Building in Washington. Griffin currently heads the space department at Johns Hopkins University's Applied Physics Laboratory. If confirmed by the full U.S. Senate, Dr. Griffin would be NASA's 11th administrator. Photo Credit: (NASA/Renee Bouchard)

  18. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-11

    U.S. Senator Barbara Mikulski, D-Md., testifies before the U.S. Senate Commerce Committee during the confirmation hearing of Dr. Michael Griffin, rear center, Tuesday, April 12, 2005, at the Russell Senate Office Building in Washington. Griffin currently heads the space department at Johns Hopkins University's Applied Physics Laboratory. If confirmed by the full U.S. Senate, Dr. Griffin would be NASA's 11th administrator. Photo Credit: (NASA/Renee Bouchard)

  19. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    U.S. Senator Barbara Mikulski, D-Md., left, talks with Michael Griffin as Senator Kay Bailey Hutchison, R-Tx., and Griffin's wife Rebecca look on prior to his testimony, Tuesday, April 12, 2005, at the Russell Senate Office Building in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit: (NASA/Renee Bouchard)

  20. Michael Griffin Senate Confirmation Hearing

    NASA Image and Video Library

    2005-04-12

    U.S. Senator Barbara Mikulski, D-Md., testifies before the U.S. Senate Commerce Committee during the confirmation hearing of Dr. Michael Griffin, right background, Tuesday, April 12, 2005, at the Russell Senate Office Building in Washington. Griffin currently heads the space department at Johns Hopkins University's Applied Physics Laboratory. If confirmed by the full U.S. Senate, Dr. Griffin would be NASA's 11th administrator. Photo Credit: (NASA/Renee Bouchard)

  1. Impact of bacteriophage Saint3 carriage on the immune evasion capacity and hemolytic potential of Staphylococcus aureus CC398.

    PubMed

    Jung, Philipp; Abdelbary, Mohamed M H; Kraushaar, Britta; Fetsch, Alexandra; Geisel, Jürgen; Herrmann, Mathias; Witte, Wolfgang; Cuny, Christiane; Bischoff, Markus

    2017-02-01

    Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) isolates of clonal complex 398 (CC398) are frequently found in Europe, and recent studies highlighted the importance of mobile genetic element (MGE) exchange for host adaptation of this lineage. Of note, one of the MGEs commonly found in human S. aureus isolates, the immune evasion cluster (IEC) harboring bacteriophage Saint3, is very rarely found in LA-MRSA CC398 isolates obtained from farm animals, but more frequently found in LA-MRSA CC398 that were retransmitted to humans. Here, we analyzed with a set of S. aureus CC398 isolates harboring/lacking φSaint3 how this MGE affects (i) phagocytosis of CC398 isolates by polymorphonuclear neutrophils (PMNs), and (ii) hemolysis of human and livestock-derived erythrocytes. Isolates lacking φSaint3 were more efficiently phagocytosed by human PMNs in whole blood phagocytosis assays than isolates harboring this bacteriophage, irrespective of their origin. Notably, a similar effect was observed when equine blood was utilized, but not detected with porcine blood. Integration of φSaint3 into LA-MRSA CC398 strains lacking this MGE confirmed these findings, as φSaint3-harboring recipients were again less efficiently ingested by PMNs in equine and human blood than their parental strains. Integration of φSaint3 strongly reduced the hemolytic potential of the culture supernatants against human-derived erythrocytes, and to a smaller extent also against porcine-derived erythrocytes, while φSaint3 integration only slightly affected the hemolytic capacities against equine-derived red blood cells. The significant protective effect of φSaint3 against phagocytosis by equine PMNs suggests that the host specificity of the IEC components might be broader than currently assumed. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. A Bibliographic Tribute to Jack Michael

    ERIC Educational Resources Information Center

    Esch, Barbara E.; Esch, John W.

    2016-01-01

    "In the late 1950's, Jack Michael, a bright but irritating young psychology instructor, moved from the Universities of Kansas to Houston to Arizona State. Along the way he befriended two nontraditional students, protected them through their Ph.D. programs, and turned them loose on the world: Teodoro Ayllon…and Montrose Wolf…" (Risley,…

  3. High Resolution Elevation Data for the Saint Louis River

    EPA Science Inventory

    Several data collections in the area of the Saint Louis River Estuary have recently become available. These include the Minnesota Elevation Mapping Project (MN Statewide LIDAR collect), South Shore LIDAR project (WI Collect), and NOAA’s bathymetric LIDAR. The EPA Mid-Continent ...

  4. 76 FR 555 - Keystone Holdings, LLC and Compagnie de Saint-Gobain; Analysis of Proposed Agreement Containing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... relating to the manufacture and sale of alumina wear tiles. To resolve the competitive concerns raised by... exclude Saint-Gobain's North American alumina wear tile business operated out of a facility in Latrobe... tile business in Latrobe or certain other assets owned or controlled by Saint-Gobain relating to the...

  5. Geologic map of Saint Lawrence Island, Alaska

    USGS Publications Warehouse

    Patton, William W.; Wilson, Frederic H.; Taylor, Theresa A.

    2011-01-01

    Saint Lawrence Island is located in the northern Bering Sea, 190 km southwest of the tip of the Seward Peninsula, Alaska, and 75 km southeast of the Chukotsk Peninsula, Russia (see index map, map sheet). It lies on a broad, shallow-water continental shelf that extends from western Alaska to northeastern Russia. The island is situated on a northwest-trending structural uplift exposing rocks as old as Paleozoic above sea level. The submerged shelf between the Seward Peninsula and Saint Lawrence Island is covered mainly with Cenozoic deposits (Dundo and Egiazarov, 1982). Northeast of the island, the shelf is underlain by a large structural depression, the Norton Basin, which contains as much as 6.5 km of Cenozoic strata (Grim and McManus, 1970; Fisher and others, 1982). Sparse test-well data indicate that the Cenozoic strata are underlain by Paleozoic and Proterozoic rocks, similar to those exposed on the Seward Peninsula (Turner and others, 1983). Saint Lawrence Island is 160 km long in an east-west direction and from 15 km to 55 km wide in a north-south direction. The east end of the island consists largely of a wave-cut platform, which has been elevated as much as 30 m above sea level. Isolated upland areas composed largely of granitic plutons rise as much as 550 m above the wave-cut platform. The central part of the island is dominated by the Kookooligit Mountains, a large Quaternary shield volcano that extends over an area of 850 km2 and rises to an elevation of 630 m. The west end of the island is composed of the Poovoot Range, a group of barren, rubble-covered hills as high as 450 m that extend from Boxer Bay on the southwest coast to Taphook Mountain on the north coast. The Poovoot Range is flanked on the southeast by the Putgut Plateau, a nearly flat, lake-dotted plain that stands 30?60 m above sea level. The west end of the island is marked by uplands underlain by the Sevuokuk pluton (unit Kg), a long narrow granite body that extends from Gambell on the

  6. Meet EPA Ecologist Michael Murrell, Ph.D.

    EPA Pesticide Factsheets

    Michael Murrel, Ph.D., is a EPA research ecologist working on the Gulf of Mexico Hypoxia Project, helping develop models of the northern Gulf to quantify the links between freshwater flowing into the Gulf from the land, nutrients, and hypoxia—“dead zones”

  7. The International Law Program at Saint Louis University.

    ERIC Educational Resources Information Center

    Dore, Isaak

    1996-01-01

    Saint Louis University (Missouri) has designed an international law curriculum to inculcate in students the idea that the Kantian notion of nations naturally united by mutual self-interest is truer today than ever, to expose students to the challenges of globalization in preparation for decision-making, and to equip them with intellectual tools to…

  8. Understanding Latter-Day Saints Education: Principles and Resources

    ERIC Educational Resources Information Center

    Morgan, Barbara

    2014-01-01

    Using historic documents of the Church of Jesus Christ of Latter-day Saints (LDS) and resources of its leaders, the principles of LDS or Mormon education and its key characteristics are described. In particular, the following characteristics are discussed: (1) the critical role of the Spirit in both teaching and learning, (2) the worthiness,…

  9. 76 FR 55904 - Michael J. Donahue; Notice of Termination of Exemption By Implied Surrender and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 6649-008] Michael J.... Date Initiated: September 1, 2011. d. Exemptee: Michael J. Donahue. e. Name and Location of Project.... Initiated Pursuant to: 18 CFR 4.106. g. Exemptee Contact Information: Mr. Michael J. Donahue, Route 3, Box...

  10. 76 FR 58264 - Michael J. Donahue; Notice of Termination of Exemption by Implied Surrender and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 6649-008] Michael J.... Date Initiated: September 13, 2011. d. Exemptee: Michael J. Donahue. e. Name and Location of Project.... Initiated Pursuant to: 18 CFR 4.106. g. Exemptee Contact Information: Mr. Michael J. Donahue, Route 3, Box...

  11. 75 FR 62635 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request... determine patients' satisfaction with services provided by or through the Michael E. DeBakey Home Care...: Patient Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number...

  12. 77 FR 69550 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-19

    ... (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request AGENCY... information needed to determine patients' satisfaction with services provided by or through the Michael E...: Patient Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number...

  13. Classification and Counter-Classification of Language on Saint Barthelemy.

    ERIC Educational Resources Information Center

    Pressman, Jon F.

    1998-01-01

    Analyzes the use of metapragmatic description in the ethnoclassification of language by native speakers on the Franco-Antillean island of Saint Barthelemy. A prevalent technique for metapragmatic description based on honorific pronouns that reflects the varied geolinguistic and generational attributes of the speakers is described. (Author/MSE)

  14. A Mosquito Survey of the Twin-Island Caribbean Nation of Saint Kitts and Nevis, 2010.

    PubMed

    Mohammed, Hamish; Evanson, Jessica; Revan, Floyd; Lee, Elise; Krecek, Rosina C; Smith, Joshua

    2015-12-01

    Adult mosquito surveys of Saint Kitts and Nevis (SKN) were performed in the dry season (March 16-23, 2010) in Saint Kitts, and the rainy season (October 18-25, 2010) in SKN. Biogents (BG) Sentinel Traps were set with CO₂and BG Lure in urban, rural, mangrove, and dry forest habitats. Mosquitoes were identified to species, and reverse transcription-polymerase chain reaction was performed on potential vector species for dengue virus (DENV), chikungunya virus (CHIKV), and West Nile virus (WNV). The most abundant species during both seasons in St. Kitts were Culex quinquefasciatus, Aedes taeniorhynchus, and Aedes aegypti. There were 3 new records for Saint Kitts: Aedes tortilis, Anopheles albimanus, and Culex nigripalpus. Traps were also set in Nevis. No mosquito pool tested positive for DENV, CHIKV, or WNV.

  15. An x-ray backlit Talbot-Lau deflectometer for high-energy-density electron density diagnostics

    DOE PAGES

    Valdivia, M. P.; Stutman, D.; Stoeckl, C.; ...

    2016-02-10

    X-ray phase-contrast techniques can measure electron density gradients in high-energy-density plasmas through refraction induced phase shifts. An 8 keV Talbot-Lau interferometer consisting of free standing ultrathin gratings was deployed at an ultra-short, high-intensity laser system using K-shell emission from a 1-30 J, 8 ps laser pulse focused on thin Cu foil targets. Grating survival was demonstrated for 30 J, 8 ps laser pulses. The first x-ray deflectometry images obtained under laser backlighting showed up to 25% image contrast and thus enabled detection of electron areal density gradients with a maximum value of 8.1 ± 0.5 × 10 23 cm ₋3more » in a low-Z millimeter sized sample. An electron density profile was obtained from refraction measurements with an error of <8%. We found the 50 ± 15 μm spatial resolution achieved across the full field of view was limited by the x-ray source-size, similar to conventional radiography.« less

  16. 75 FR 23589 - Safety Zones; Blasting Operations and Movement of Explosives, St. Marys River, Sault Sainte Marie...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket No. USCG-2010-0290] RIN 1625-AA00 Safety Zones; Blasting Operations and Movement of Explosives, St. Marys River, Sault Sainte Marie... Movement of Explosives, St. Marys River, Sault Sainte Marie, MI. (a) Location. The following areas are...

  17. Analogies between Kirchhoff plates and functionally graded Saint-Venant beams under torsion

    NASA Astrophysics Data System (ADS)

    Barretta, Raffaele; Luciano, Raimondo

    2015-05-01

    Exact solutions of elastic Kirchhoff plates are available only for special geometries, loadings and kinematic boundary constraints. An effective solution procedure, based on an analogy between functionally graded orthotropic Saint-Venant beams under torsion and inhomogeneous isotropic Kirchhoff plates, with no kinematic boundary constraints, is proposed. The result extends the one contributed in Barretta (Acta Mech 224(12):2955-2964, 2013) for the special case of homogeneous Saint-Venant beams under torsion. Closed-form solutions for displacement, bending-twisting moment and curvature fields of an elliptic plate, corresponding to a functionally graded orthotropic beam, are evaluated. A new benchmark for computational mechanics is thus provided.

  18. Surface Modified Particles By Multi-Step Michael-Type Addition And Process For The Preparation Thereof

    DOEpatents

    Cook, Ronald Lee; Elliott, Brian John; Luebben, Silvia DeVito; Myers, Andrew William; Smith, Bryan Matthew

    2005-05-03

    A new class of surface modified particles and a multi-step Michael-type addition surface modification process for the preparation of the same is provided. The multi-step Michael-type addition surface modification process involves two or more reactions to compatibilize particles with various host systems and/or to provide the particles with particular chemical reactivities. The initial step comprises the attachment of a small organic compound to the surface of the inorganic particle. The subsequent steps attach additional compounds to the previously attached organic compounds through reactive organic linking groups. Specifically, these reactive groups are activated carbon—carbon pi bonds and carbon and non-carbon nucleophiles that react via Michael or Michael-type additions.

  19. The Segmented Aperture Interferometric Nulling Testbed (SAINT) I: overview and air-side system description

    NASA Astrophysics Data System (ADS)

    Hicks, Brian A.; Lyon, Richard G.; Petrone, Peter; Ballard, Marlin; Bolcar, Matthew R.; Bolognese, Jeff; Clampin, Mark; Dogoda, Peter; Dworzanski, Daniel; Helmbrecht, Michael A.; Koca, Corina; Shiri, Ron

    2016-07-01

    This work presents an overview of the Segmented Aperture Interferometric Nulling Testbed (SAINT), a project that will pair an actively-controlled macro-scale segmented mirror with the Visible Nulling Coronagraph (VNC). SAINT will incorporate the VNC's demonstrated wavefront sensing and control system to refine and quantify end-to-end high-contrast starlight suppression performance. This pathfinder testbed will be used as a tool to study and refine approaches to mitigating instabilities and complex diffraction expected from future large segmented aperture telescopes.

  20. The Segmented Aperture Interferometric Nulling Testbed (SAINT) I: Overview and Air-side System Description

    NASA Technical Reports Server (NTRS)

    Hicks, Brian A.; Lyon, Richard G.; Petrone, Peter, III; Bolcar, Matthew R.; Bolognese, Jeff; Clampin, Mark; Dogoda, Peter; Dworzanski, Daniel; Helmbrecht, Michael A.; Koca, Corina; hide

    2016-01-01

    This work presents an overview of the This work presents an overview of the Segmented Aperture Interferometric Nulling Testbed (SAINT), a project that will pair an actively-controlled macro-scale segmented mirror with the Visible Nulling Coronagraph (VNC). SAINT will incorporate the VNCs demonstrated wavefront sensing and control system to refine and quantify the end-to-end system performance for high-contrast starlight suppression. This pathfinder system will be used as a tool to study and refine approaches to mitigating instabilities and complex diffraction expected from future large segmented aperture telescopes., a project that will pair an actively-controlled macro-scale segmented mirror with the Visible Nulling Coronagraph (VNC). SAINT will incorporate the VNCs demonstrated wavefront sensing and control system to refine and quantify the end-to-end system performance for high-contrast starlight suppression. This pathfinder system will be used as a tool to study and refine approaches to mitigating instabilities and complex diffraction expected from future large segmented aperture telescopes.

  1. Prospecting Anticancer Compounds in Actinomycetes Recovered from the Sediments of Saint Peter and Saint Paul's Archipelago, Brazil.

    PubMed

    Ferreira, Elthon G; Torres, Maria da Conceição M; da Silva, Alison B; Colares, Larissa L F; Pires, Karine; Lotufo, Tito M C; Silveira, Edilberto R; Pessoa, Otília D L; Costa-Lotufo, Leticia V; Jimenez, Paula C

    2016-09-01

    Saint Peter and Saint Paul's Archipelago is a collection of 15 islets and rocks remotely located in the equatorial Atlantic Ocean. In this particular site, the present project intended to assess the biodiversity and biotechnological potential of bacteria from the actinomycete group. This study presents the first results of this assessment. From 21 sediment samples, 268 strains were isolated and codified as BRA followed by three numbers. Of those, 94 strains were grown in liquid media and submitted to chemical extractions with AcOEt (A), BuOH (B), and MeOH (M). A total of 224 extracts were screened for their cytotoxic activity and 41 were significantly active against HCT-116 cancer cells. The obtained IC 50 values ranged from 0.04 to 31.55 μg/ml. The HR-LC/MS dereplication analysis of the active extracts showed the occurrence of several known anticancer compounds. Individual compounds, identified using HR-MS combined with analysis of the AntiMarin database, included saliniketals A and B, piericidins A and C and glucopiericidin A, staurosporine, N-methylstaurosporine, hydroxydimethyl-staurosporine and N-carbamoylstaurosporine, salinisporamycin A, and rifamycins S and B. BRA-199, identified as Streptomyces sp., was submitted to bioassay-guided fractionation, leading to isolation of the bioactive piericidins A and C, glucopiericidin, and three known diketopiperazines, cyclo(l-Phe-trans-4-OH-l-Pro), cyclo(l-Phe-l-Pro), and cyclo(l-Trp-l-Pro). © 2016 Wiley-VHCA AG, Zürich.

  2. Michael Griffin Discusses Exploration Architecture Study

    NASA Image and Video Library

    2005-09-18

    NASA Administrator Michael Griffin discusses the results of the agency's exploration architecture study on Monday, Sept. 19, 2005, at NASA Headquarters in Washington. The study made specific design recommendations for a vehicle to carry crews into space, a family of launch vehicles to take missions to the moon and beyond, and a "lunar mission architecture" for landing on the moon. Photo Credit: (NASA/Bill Ingalls)

  3. Solving the Housing Equation: Michael P. Johnson

    ERIC Educational Resources Information Center

    Roach, Ronald

    2005-01-01

    Dr. Michael P. Johnson, an associate professor of management science and urban affairs at the H. John Heinz III School of Public Policy and Management at Carnegie Mellon University in Pittsburgh, is taking management science tools and innovative information technology applications to the housing field. Concerned that organizations that develop and…

  4. Pathology and the posture of the La Chapelle-aux-Saints Neandertal.

    PubMed

    Trinkaus, E

    1985-05-01

    The depiction of the Neandertals as incompletely erect was based primarily on Boule's (1911, 1912a, 1913) analysis of the La Chapelle-aux-Saints 1 partial skeleton. The inaccurate aspects of Boule's postural reconstruction were corrected during the 1950s. However, it has come to be believed, following Straus and Cave (1957), that Boule's errors of reconstruction were due to the diseased condition of the La Chapelle-aux-Saints 1 remains, rather than to Boule's misinterpretation of morphology. The abnormalities on the La Chapelle-aux-Saints 1 postcranium include: lower cervical, upper thoracic, and lower thoracic intervertebral degenerative joint disease (DJD), a distal fracture of a mid-thoracic rib, extensive DJD of the left hip, DJD of the right fifth proximal interphalangeal articulation, bilateral humeral head eburnation, and minor exostosis formation on the right humerus, ulna, and radius. These were associated with extensive alveolar inflammation including apical abscesses and antemortem tooth loss, some temporomandibular DJD, bilateral auditory exostoses, and minimal occipital condyle DJD. None of these abnormalities significantly affected Boule's Neandertal postural reconstruction, and a review of his analysis indicates that early twentieth century interpretations of skeletal morphology (primarily of the cranium, cervical vertebrae, lumbar and sacral vertebrae, proximal femora and tibiae, posterior tarsals, and hallucial tarsometatarsal joint), combined with Boule's evolutionary preconceptions, were responsible for his mistaken view of Neandertal posture.

  5. SRTM Stereo Pair with Landsat Overlay: Miquelon and Saint Pierre Islands

    NASA Image and Video Library

    2000-10-20

    This stereoscopic satellite image showing Miquelon and Saint Pierre Islands, located south of Newfoundland, Canada, was generated by draping NASA Landsat satellite image over a preliminary Shuttle Radar Topography Mission SRTM elevation model.

  6. "Anti-Michael addition" of Grignard reagents to sulfonylacetylenes: synthesis of alkynes.

    PubMed

    Esteban, Francisco; Boughani, Lazhar; García Ruano, José L; Fraile, Alberto; Alemán, José

    2017-05-10

    In this work, the addition of Grignard reagents to arylsulfonylacetylenes, which undergoes an "anti-Michael addition", resulting in their alkynylation under very mild conditions is described. The simplicity of the experimental procedure and the functional group tolerance are the main features of this methodology. This is an important advantage over the use of organolithium at -78 °C that we previously reported. Moreover, the synthesis of diynes and other examples showing functional group tolerance in this anti-Michael reaction is also presented.

  7. Egg deposition by lithophilic-spawning fishes in the Detroit and Saint Clair Rivers, 2005–14

    USGS Publications Warehouse

    Prichard, Carson G.; Craig, Jaquelyn M.; Roseman, Edward F.; Fischer, Jason L.; Manny, Bruce A.; Kennedy, Gregory W.

    2017-03-14

    A long-term, multiseason, fish egg sampling program conducted annually on the Detroit (2005–14) and Saint Clair (2010–14) Rivers was summarized to identify where productive fish spawning habitat currently exists. Egg mats were placed on the river bottom during the spring and fall at historic spawning areas and candidate fish spawning habitat restoration sites throughout both rivers. Widespread evidence was found of lithophilic spawning by numerous native fish species, including walleye (Sander vitreus), lake whitefish (Coregonus clupeaformis), lake sturgeon (Acipenser fulvescens), suckers (Catostomidae spp.), and trout-perch (Percopsis omiscomaycus). Walleye, lake whitefish, and suckers spp. spawned in nearly every region of each river in all years on both reef and nonreef substrates. Lake sturgeon eggs were collected almost exclusively over constructed reefs. Catch-per-unit effort of walleye, lake whitefish, and sucker eggs was much greater in the Detroit River than in the Saint Clair River, while Saint Clair River sites supported the greatest collections of lake sturgeon eggs. Collections during this study of lake sturgeon eggs on man-made spawning reefs suggest that artificial reefs may be an effective tool for restoring fish populations in the Detroit and Saint Clair Rivers; however, the quick response of lake sturgeon to spawn on newly constructed reefs and the fact that walleye, lake whitefish, and sucker eggs were often collected over substrate with little interstitial space to protect eggs from siltation and predators suggests that lack of suitable spawning habitat may continue to limit reproduction of lithophilic-spawning fish species in the Saint Clair-Detroit River System.

  8. Reframing Michael Scott: Exploring Inappropriate Workplace Communication

    ERIC Educational Resources Information Center

    Schaefer, Zachary A.

    2010-01-01

    Individuals who work in professional settings interact with others who may exhibit a variety of cultural beliefs and decision-making approaches. Page (2007) argues that cognitive diversity (i.e., how people approach and attempt to solve problems) is a vital asset in effective organizations. Michael Scott, who portrays the inept main character on…

  9. Against Dogma: A Reply to Michael Swan.

    ERIC Educational Resources Information Center

    Widdowson, H. G.

    1985-01-01

    Replies to two articles by Michael Swan entitled "A Critical Look at the Communicative Approach." Argues that Swan presents a distorted version of the communicative approach so as to present his own ideas more effectively and that he fails to offer evidence for his position on the practice of English language teaching. (SED)

  10. The legacy of Michael Balint.

    PubMed

    Johnson, Alan H; Brock, Clive D; Zacarias, Ashleigh

    2014-01-01

    Michael Balint's lead article, "Repeat Prescription Patients: Are They An Identifiable Group?" inaugurated the first issue of Psychiatry in Medicine, Vol. 1, No. 1, 1970. A few years later, this Journal would be renamed International Journal of Psychiatry in Medicine (IJPM). Who is this author of over 165 papers, 10 books, practicing psychoanalyst from 1926 to 1970, director of the Budapest Psychoanalytic Institute from 1935 to 1939, consultant at the Tavistock Clinic from 1948 to 1961, President of the British Psycho-Analytical Society from 1968 to 1970, literary executor of Sandor Ferenczi, a foremost theorist of object relations, and international educator and statesman for general practitioners? We would like to review for you some of the formative experiences in Michael's life that wedded psychoanalysis and general practice, and how they contributed to his major educational commitment over 40 years to furthering the understanding and integration of psychosocial factors in the practice of primary healthcare as experienced by doctors all over the world. We would also like to highlight some of his major insights and see to what extent they are incorporated in contemporary medical education and practice. We believe that some of his major insights have been neglected and others have been further amplified and extended. Our intention is to speak not only to medical students who desire to pursue medicine related directly to patient care but as well to seasoned practitioners who continue on a daily basis to care for individual patients and their families.

  11. Diet and behavior of the Saint-Césaire Neanderthal inferred from biogeochemical data inversion.

    PubMed

    Balter, Vincent; Simon, Laurent

    2006-10-01

    Biogeochemistry is a powerful tool for dietary reconstruction, and mixing equations can be used to quantify the contribution of multiple sources to an individual's diet. The goals of this paper are: 1) to generalize the inverse method to dietary mixtures; and 2) to reconstruct the diet of the Saint-Césaire Neanderthal using Sr/Ca and Ba/Ca data of the mineral fraction of bone (hydroxylapatite), and with published delta13C and delta15N data of the associated organic fraction of bone (collagen). A new method is proposed to calculate the maximum diagenetic contribution of the Sr/Ba ratio, assuming that the soil soluble fraction is the diagenetic end-member and, for a given fraction of diagenesis, allows the restoration of the original Sr/Ba ratio. Considering the Saint-Césaire Châtelperronian mammalian assemblage as the meat source, and on the basis of available Sr, Ba, and Ca contents of plants, the results indicate that the percentage of plants in the Neanderthal's diet must have been close to zero for realistic Sr and Ba impoverishment between diet and hydroxylapatite. Contrary to previous studies, it is shown that fish could constitute a significant proportion (30%) of the diet of the Saint-Césaire Neanderthal. However, this mass balance solution is not supported by the zooarchaeological data. When the entire faunal assemblage is considered as the dietary source, the calculation shows that bovids (except reindeer) represent the greatest percentage of consumed meat (58%), followed by horses/rhinoceros (22%), reindeer (13%), and mammoths (7%). These respective percentages are in close accordance with zooarchaeological records, suggesting that the faunal assemblage associated with the Neanderthal of Saint-Césaire reliably reflects what he ate during the last few years of his life. In behavioral terms, this result supports the hypothesis that this Neanderthal carried the foodstuffs back to the Saint-Césaire shelter before their consumption.

  12. 33 CFR 165.763 - Moving and Fixed Security Zone, Port of Fredericksted, Saint Croix, U.S. Virgin Islands.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., Saint Croix, U.S. Virgin Islands. (a) Location. A moving and fixed security zone is established that surrounds all cruise ships entering, departing, mooring or anchoring in the Port of Fredericksted, Saint Croix, U.S. Virgin Islands. The security zone extends from the cruise ship outward and forms a 50-yard...

  13. 33 CFR 165.763 - Moving and Fixed Security Zone, Port of Fredericksted, Saint Croix, U.S. Virgin Islands.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., Saint Croix, U.S. Virgin Islands. (a) Location. A moving and fixed security zone is established that surrounds all cruise ships entering, departing, mooring or anchoring in the Port of Fredericksted, Saint Croix, U.S. Virgin Islands. The security zone extends from the cruise ship outward and forms a 50-yard...

  14. 33 CFR 165.763 - Moving and Fixed Security Zone, Port of Fredericksted, Saint Croix, U.S. Virgin Islands.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., Saint Croix, U.S. Virgin Islands. (a) Location. A moving and fixed security zone is established that surrounds all cruise ships entering, departing, mooring or anchoring in the Port of Fredericksted, Saint Croix, U.S. Virgin Islands. The security zone extends from the cruise ship outward and forms a 50-yard...

  15. 33 CFR 165.763 - Moving and Fixed Security Zone, Port of Fredericksted, Saint Croix, U.S. Virgin Islands.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., Saint Croix, U.S. Virgin Islands. (a) Location. A moving and fixed security zone is established that surrounds all cruise ships entering, departing, mooring or anchoring in the Port of Fredericksted, Saint Croix, U.S. Virgin Islands. The security zone extends from the cruise ship outward and forms a 50-yard...

  16. 33 CFR 165.763 - Moving and Fixed Security Zone, Port of Fredericksted, Saint Croix, U.S. Virgin Islands.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., Saint Croix, U.S. Virgin Islands. (a) Location. A moving and fixed security zone is established that surrounds all cruise ships entering, departing, mooring or anchoring in the Port of Fredericksted, Saint Croix, U.S. Virgin Islands. The security zone extends from the cruise ship outward and forms a 50-yard...

  17. MICHAEL "RUDI" RUDOLPHI SPEAKING AT MISSION SUCCESS FORUM

    NASA Image and Video Library

    2016-06-16

    MICHAEL "RUDI" RUDOLPHI GESTURES DURING A "MISSION SUCCESS IS IN OUR HANDS" SHARED EXPERIENCES FORUM JUNE 16, WHERE HE SPOKE ABOUT HIS "UNFORGETTABLE" EXPERIENCES AS A SENIOR NASA REPRESENTATIVE OVERSEEING DEBRIS RECOVERY EFFORTS FOLLOWING THE LOSS OF SPACE SHUTTLE COLUMBIA AND ITS CREW.

  18. Michael Driver: A Career Life to Remember

    ERIC Educational Resources Information Center

    Sundby, Dianne; Derr, C. Brooklyn

    2007-01-01

    Purpose: The purpose of this paper is to present a retrospective of the career life of Michael Driver, from the time of his Princeton graduate studies and early faculty years at Purdue University through the over three decades he spent at USC. Design/methodology/approach: The history and development of his theoretical and research interests are…

  19. Michael Walzer's Politics, in Theory and Practice

    ERIC Educational Resources Information Center

    Williams, Jeffrey J.

    2012-01-01

    Before all the talk about "public intellectuals," Michael Walzer was one. For 50 years, he has gone back and forth between positions at Princeton and Harvard Universities and then at the Institute for Advanced Study, in Princeton, New Jersey, where he is now emeritus. His writings appear regularly in "Dissent" magazine, which he has co-edited for…

  20. Reading Michael Apple--The Sociological Imagination at Work

    ERIC Educational Resources Information Center

    Ball, Stephen J.

    2007-01-01

    This article discusses Michael Apple's contribution to the sociology of education and education policy analysis and the politics of education. It focuses on ways of "reading" Apple as an intellectual and an activist and looks at the trajectory of his work over a long and illustrious career.

  1. Deformation during terrane accretion in the Saint Elias orogen, Alaska

    USGS Publications Warehouse

    Bruhn, R.L.; Pavlis, T.L.; Plafker, G.; Serpa, L.

    2004-01-01

    The Saint Elias orogen of southern Alaska and adjacent Canada is a complex belt of mountains formed by collision and accretion of the Yakutat terrane into the transition zone from transform faulting to subduction in the northeast Pacific. The orogen is an active analog for tectonic processes that formed much of the North American Cordillera, and is also an important site to study (1) the relationships between climate and tectonics, and (2) structures that generate large- to great-magnitude earthquakes. The Yakutat terrane is a fragment of the North American plate margin that is partly subducted beneath and partly accreted to the continental margin of southern Alaska. Interaction between the Yakutat terrane and the North American and Pacific plates causes significant differences in the style of deformation within the terrane. Deformation in the eastern part of the terrane is caused by strike-slip faulting along the Fairweather transform fault and by reverse faulting beneath the coastal mountains, but there is little deformation immediately offshore. The central part of the orogen is marked by thrusting of the Yakutat terrane beneath the North American plate along the Chugach-Saint Elias fault and development of a wide, thin-skinned fold-and-thrust belt. Strike-slip faulting in this segment may he localized in the hanging wall of the Chugach-Saint Elias fault, or dissipated by thrust faulting beneath a north-northeast-trending belt of active deformation that cuts obliquely across the eastern end of the fold-and-thrust belt. Superimposed folds with complex shapes and plunging hinge lines accommodate horizontal shortening and extension in the western part of the orogen, where the sedimentary cover of the Yakutat terrane is accreted into the upper plate of the Aleutian subduction zone. These three structural segments are separated by transverse tectonic boundaries that cut across the Yakutat terrane and also coincide with the courses of piedmont glaciers that flow from

  2. Production of Low-Freezing-Point Highly Branched Alkanes through Michael Addition.

    PubMed

    Jing, Yaxuan; Xia, Qineng; Liu, Xiaohui; Wang, Yanqin

    2017-12-22

    A new approach for the production of low-freezing-point, high-quality fuels from lignocellulose-derived molecules was developed with Michael addition as the key step. Among the investigated catalysts, CoCl 2 ⋅6 H 2 O was found most active for the Michael addition of 2,4-pentanedione with FA (single aldol adduct of furfural and acetone, 4-(2-furanyl)-3-butene-2-one). Over CoCl 2 ⋅6 H 2 O, a high carbon yield of C 13 oxygenates (about 75 %) can be achieved under mild conditions (353 K, 20 h). After hydrodeoxygenation, low-freezing-point (<223 K) branched alkanes with 13 carbons within jet fuel ranges were obtained over a Pd/NbOPO 4 catalyst. Furthermore, C 18,23 fuel precursors could be easily synthesized through Michael addition of 2,4-pentanedione with DFA (double-condensation product of furfural and acetone) under mild conditions and the molar ratio of C 18 /C 23 is dependent on the reaction conditions of Michael addition. After hydrodeoxygenation, high density (0.8415 g mL -1 ) and low-freezing-point (<223 K) branched alkanes with 18, 23 carbons within lubricant range were also obtained over a Pd/NbOPO 4 catalyst. These highly branched alkanes can be directly used as transportation fuels or additives. This work opens a new strategy for the synthesis of highly branched alkanes with low freezing point from renewable biomass. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. [Saint-Jacques de Besançon Hospital].

    PubMed

    Deridder, Annick

    2007-01-01

    The first plan (1670) was carried out by Archbishop Antoine Pierre 1st de Grammont under the Spanish administration, with the aid of the Community Saint Marthe whose Congregation was at the start of a new monastic order and whose last members left Besançon a few years ago. At the beginning King Louis XIVth supported the building of the new hospital (1865) which was intended to shelter numerous soldiers like some other hospitals of the time. The main walls were ended in 1701 and the garden in 1702. The first patients were received in 1691. The cross-shaped Italian building is centred on a chapel and looks like many other buildings such as "La Salpêtriere" in Paris. It superseded the ancient medieval building "Saint-Jacques des Arènes" vowed to the travellers and pilgrims, the site of which was on the main crossing roads but on too small a space. The main architect was Canon Jacques Magnin, the material was found in the country and the gorgeous railings were forged by a local craftsman Chappuis. A local practitioner Gabriel Gascon bequeathed his sumptuous apothecary's shop. Some extensions of the building occured during the following centuries: a wing towards the garden, the "Couvent du Refuge" and its brilliant baroque chapel allowed the whole building to have a praise worthy chapel. At last the "Hôtel de Mont martin" initially built for Cardinal Granvelle was joined to the main hospital and became the Maternity Hospital.

  4. Fabrication of high aspect grating using bonded substrate for X-ray refraction imaging by Talbot-Lau interferometer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tada, Takuji; Murakoshi, Dai; Ishii, Hiroyasu

    2012-07-31

    In order to improve the image quality of X-ray refraction images using a Talbot-Lau interferometer, we have been attempting to fabricate gratings with high aspect ratio. In our attempt, deep grooves of grating structure were channeled on a Si substrate bonded by Au diffusion bonding method, and the grooves were filled with Au where the Au layer used for the bonding Si substrate was acting as a seed layer of Au electroplating. From the results of a visibility measurement and a cross sectional SEM image, it was confirmed that the grooves with a pitch of 5.8 {mu}m and a depthmore » of 100 {mu}m could be successfully filled with Au over a large area of 72 Multiplication-Sign 80 mm{sup 2}. Using this grating, the X-ray refraction images for the cartilage of a knee joint of a livestock pig could be obtained where SPS method was employed for the single-shot image acquisition.« less

  5. Scripture-Based Discourses of Latter-Day Saint and Methodist Youths

    ERIC Educational Resources Information Center

    Rackley, Eric D.

    2014-01-01

    Drawing on social and cultural perspectives of literacy, conceptualizations of religious literacies, and Gee's notion of Discourses, I develop a framework for exploring 16 Latter-day Saint and Methodist youths' religious literacies as social and cultural practice. This work grows out of the increasingly important role that religion plays…

  6. Astronaut Michael Clifford takes a break during bailout training

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Astronaut Michael R.U. (Rich) Clifford takes a break while video taping crew mates in training in the JSC Weightless Environment Training Facility (WETF). He is pictured with Trent G. Keeple, a member of the training staff assigned to STS-59.

  7. Michael Hand, Indoctrination and the Inculcation of Belief

    ERIC Educational Resources Information Center

    Tan, Charlene

    2004-01-01

    In 'Religious Upbringing Reconsidered,' Michael Hand revisits the debate on the right of parents to give their children a religious upbringing in a liberal context. According to him, the logical difficulty lies in the fact that parents cannot both impart religious beliefs and avoid indoctrination. While Peter Gardner and Jim Mackenzie have…

  8. Consistent initial conditions for the Saint-Venant equations in river network modeling

    NASA Astrophysics Data System (ADS)

    Yu, Cheng-Wei; Liu, Frank; Hodges, Ben R.

    2017-09-01

    Initial conditions for flows and depths (cross-sectional areas) throughout a river network are required for any time-marching (unsteady) solution of the one-dimensional (1-D) hydrodynamic Saint-Venant equations. For a river network modeled with several Strahler orders of tributaries, comprehensive and consistent synoptic data are typically lacking and synthetic starting conditions are needed. Because of underlying nonlinearity, poorly defined or inconsistent initial conditions can lead to convergence problems and long spin-up times in an unsteady solver. Two new approaches are defined and demonstrated herein for computing flows and cross-sectional areas (or depths). These methods can produce an initial condition data set that is consistent with modeled landscape runoff and river geometry boundary conditions at the initial time. These new methods are (1) the pseudo time-marching method (PTM) that iterates toward a steady-state initial condition using an unsteady Saint-Venant solver and (2) the steady-solution method (SSM) that makes use of graph theory for initial flow rates and solution of a steady-state 1-D momentum equation for the channel cross-sectional areas. The PTM is shown to be adequate for short river reaches but is significantly slower and has occasional non-convergent behavior for large river networks. The SSM approach is shown to provide a rapid solution of consistent initial conditions for both small and large networks, albeit with the requirement that additional code must be written rather than applying an existing unsteady Saint-Venant solver.

  9. Large-angle x-ray scatter in Talbot-Lau interferometry for breast imaging

    PubMed Central

    Vedantham, Srinivasan; Shi, Linxi; Karellas, Andrew

    2014-01-01

    Monte Carlo simulations were used to investigate large-angle x-ray scatter at design energy of 25 keV during small field of view (9.6 cm × 5 cm) differential phase contrast imaging of the breast using Talbot-Lau interferometry. Homogenous, adipose and fibroglandular breasts of uniform thickness ranging from 2 to 8 cm encompassing the field of view were modeled. Theoretically determined transmission efficiencies of the gratings were used to validate the Monte Carlo simulations, followed by simulations to determine the x-ray scatter reaching the detector. The recorded x-ray scatter was classified into x-ray photons that underwent at least one Compton interaction (incoherent scatter) and Rayleigh interaction alone (coherent scatter) for further analysis. Monte Carlo based estimates of transmission efficiencies showed good correspondence (r2 > 0.99) with theoretical estimates. Scatter-to-primary ratio increased with increasing breast thickness, ranging from 0.11 to 0.22 for 2 to 8 cm thick adipose breasts and from 0.12 to 0.28 for 2 to 8 cm thick fibroglandular breasts. The analyzer grating reduced incoherent scatter by ~18% for 2 cm thick adipose breast and by ~35% for 8 cm thick fibroglandular breast. Coherent scatter was the dominant contributor to the total scatter. Coherent-to-incoherent scatter ratio ranged from 2.2 to 3.1 for 2 to 8 cm thick adipose breasts and from 2.7 to 3.4 for 2 to 8 cm thick fibroglandular breasts. PMID:25295630

  10. Case Study of a College that Closed: Saint Mary's College

    ERIC Educational Resources Information Center

    Brown, Alice W.

    2011-01-01

    Few colleges choose to close. One that did was Saint Mary's College in Raleigh, North Carolina. Although trustees resisted for a decade, they ultimately made the decision before an anticipated denial of accreditation, allowing the college to control its final days in ways not possible for those who wait until an outside agency forces closure. This…

  11. Numerical modeling of gravel bed river response to meander straightening: The coupling between the evolution of bed pavement and long profile

    NASA Astrophysics Data System (ADS)

    Talbot, Tracey; Lapointe, Michel

    2002-06-01

    Artificial meander straightening (rectification) was conducted in the early 1960s along the Sainte-Marguerite River, Canada, in order to facilitate highway construction along the valley. Previous studies [Talbot and Lapointe, 2002] confirm that vertical reprofiling, coupled with pavement coarsening in the degrading reach, were the main responses counteracting the disequilibrium in gravel transport rates triggered at rectification of this system. Numerical simulations, using SEDROUT2.0, a one-dimensional hydraulic and sediment transport model, and validated against the observed channel response, show the important role played by an advancing wave of pavement coarsening down the rectified reach in modulating the bed degradation response. Simulations extending into the future reveal an asymptotically slowing approach to equilibrium in the middle of the 21st century, with a response half-time of the order of 10 years. In near-threshold gravel bed systems like the Sainte-Marguerite River, pavement coarsening after rectification buffers the system against extreme degradation. Most significantly for watershed management, this also appears to severely limit the extent of propagation of degradation upstream of the rectification.

  12. [Saints and illnesses in faith and paleopathological evidences].

    PubMed

    Fulcheri, Ezio

    2006-01-01

    The exhumation of the natural mummies of Beata Margherita di Savoia (1390-1464) and of St. Caterina Fieschi Adorno (1447-1510) has not been followed by autopsy or histological exams. The aim has been to preserve the integrity of the saints' corpses. We have thus proceeded to a confrontation between data gathered from chronicles and hagiographies and radiological exams and macroscopic observations. The article aims at establishing a model for a multidisciplinar approach to paleopathological research, integrating historical research and medical knowledge.

  13. Performance-based organizations : issues for the Saint Lawrence Seaway Development Corporation proposal

    DOT National Transportation Integrated Search

    1997-05-01

    Report to Congressional Committees. This report (1) compares the characteristics of the Next Steps program and the PBO concept and (2) describes the changes and effects the PBO concept potentially could have on the Saint Lawrence Seaway Development C...

  14. 33 CFR 165.T09-0290 - Safety Zones; Blasting Operations and Movement of Explosives, St. Marys River, Sault Sainte Marie...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety Zones; Blasting Operations and Movement of Explosives, St. Marys River, Sault Sainte Marie, MI. 165.T09-0290 Section 165.T09-0290... Movement of Explosives, St. Marys River, Sault Sainte Marie, MI. (a) Location. The following areas are...

  15. [On the medical and publishing activities of the community of Saint Eugene].

    PubMed

    2012-01-01

    The article deals with the role the physicians played in organization and functioning of the Community of Saint Eugene in St. Petersburg in 1882-1918. The typography production of the Community being of interest for history of medicine is examined.

  16. Paracelsus confronts the saints: miracles, healing and the secularization of magic.

    PubMed

    Webster, C

    1995-12-01

    The sixteenth and seventeenth centuries witnessed an erosion of the role played by the church in healing. Magical practices mediated by the church were replaced by the resources of medicine. This represented an important cultural development and it is often regarded as a manifestation of increasing secularization, the decline of magic and rise of science. This paper examines this issue with special reference to miraculous healing associated with saints, which constituted one of the most important facets of magic controlled by the church. It will be suggested that Paracelsus (Theophrast von Hohenheim, 1493-1541) played an important part in the argument concerning the miraculous powers of saints. Many works by Paracelsus produced at various points in his career were relevant to this issue, but De causis morborum invisibilium, the sequel to his important Opus Paraminum (1531), was especially significant. The question of miraculous healing was therefore important in the first, full presentation of the new system of medicine developed by Paracelsus. Modern commentators have understandably found De causis morborum invisibilium less intelligible and congenial than the more accessible Opus Paramirum. But the former was important to Paracelsus, and it addressed problems that were fundamental to his audience. This case-study shows how conclusions reached by Paracelsus about medical questions were integrally tied up with his theological standpoint and with his wider reaction to the acute crisis of confidence which affected the church and the established social order at the beginning of the sixteenth century. By eliminating the miraculous intervention of saints and promoting the secularization of magic, Paracelsus was contributing to one of the important cultural changes associated with the Reformation.

  17. Homelessness and Work Experience: Two Years in Saint Paul. Final Report.

    ERIC Educational Resources Information Center

    Davis, Dennis R.

    A study explored the role of work experience in addressing problems of homeless people in Saint Paul (Minnesota) during the 1989-91 grant cycles of the McKinney Job Training for the Homeless Demonstration Program. The program included a number of elements: outreach, intake, assessment and enrollment, orientation, work experience, basic…

  18. 76 FR 624 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request... Form 10-0476).'' SUPPLEMENTARY INFORMATION: Title: Patient Satisfaction Survey Michael E. DeBakey Home... satisfaction with the quality of services/care provided by home care program staff. An agency may not conduct...

  19. The Holocaust and Education: An Interview with Michael Berenbaum.

    ERIC Educational Resources Information Center

    Goldberg, Mark

    1997-01-01

    In January 1997, Michael Berenbaum became president and chief executive officer of Survivors of the Shoah Visual History Foundation, the organization established by filmmaker Steven Spielberg after completing "Schindler's List." Since 1994, the foundation has been recording eyewitness testimony on the Holocaust. Berenbaum's mandate is to…

  20. Concordia U. Saint Paul Will Slash Tuition by One-Third

    ERIC Educational Resources Information Center

    Supiano, Beckie

    2012-01-01

    Concordia University Saint Paul will reduce the sticker price of its tuition and fees by $10,000, or about 33 percent, for the 2013-2014 academic year. Tuition and fees for all new and returning students in the traditional undergraduate program will drop to $19,700 next year from $29,700 this year, while the price of room and board will not…

  1. Development of flood-inundation maps for the Mississippi River in Saint Paul, Minnesota

    USGS Publications Warehouse

    Czuba, Christiana R.; Fallon, James D.; Lewis, Corby R.; Cooper, Diane F.

    2014-01-01

    Digital flood-inundation maps for a 6.3-mile reach of the Mississippi River in Saint Paul, Minnesota, were developed through a multi-agency effort by the U.S. Geological Survey in cooperation with the U.S. Army Corps of Engineers and in collaboration with the National Weather Service. The inundation maps, which can be accessed through the U.S. Geological Survey Flood Inundation Mapping Science Web site at http://water.usgs.gov/osw/flood_inundation/ and the National Weather Service Advanced Hydrologic Prediction Service site at http://water.weather.gov/ahps/inundation.php, depict estimates of the areal extent and depth of flooding corresponding to selected water levels (stages) at the U.S. Geological Survey streamgage at the Mississippi River at Saint Paul (05331000). The National Weather Service forecasted peak-stage information at the streamgage may be used in conjunction with the maps developed in this study to show predicted areas of flood inundation. In this study, flood profiles were computed for the Mississippi River by means of a one-dimensional step-backwater model. The hydraulic model was calibrated using the most recent stage-discharge relation at the Robert Street location (rating curve number 38.0) of the Mississippi River at Saint Paul (streamgage 05331000), as well as an approximate water-surface elevation-discharge relation at the Mississippi River at South Saint Paul (U.S. Army Corps of Engineers streamgage SSPM5). The model also was verified against observed high-water marks from the recent 2011 flood event and the water-surface profile from existing flood insurance studies. The hydraulic model was then used to determine 25 water-surface profiles for flood stages at 1-foot intervals ranging from approximately bankfull stage to greater than the highest recorded stage at streamgage 05331000. The simulated water-surface profiles were then combined with a geographic information system digital elevation model, derived from high-resolution topography

  2. Dr. Michael DeBakey "is a magician of the heart…"

    MedlinePlus

    ... Dr. DeBakey with NLM's David Nash and admiring students from the Michael E. DeBakey High School for ... medical research as the means of discovering improved methods of diagnosis, treatment, prevention, and cure. As far ...

  3. 78 FR 6851 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request AGENCY... Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number: 2900-0775. Type... gather feedback from patients regarding their satisfaction with the quality of services/care provided by...

  4. Michael Polanyi on the Education and Knowledge of Scientists.

    ERIC Educational Resources Information Center

    Jacobs, Struan

    2000-01-01

    Explains why teachers addressing the nature of science should know the work of Michael Polanyi. Outlines Polanyi's intellectual career and examines his ideas on the education of scientists, research, and knowledge. Polanyi presaged Kuhn, Feyerabend, and the constructivists, yet insisted that science produces true knowledge about reality. (Contains…

  5. Three saints with deformed extremities in an Italian Renaissance altarpiece.

    PubMed

    Albury, W R; Weisz, G M

    2017-03-01

    A fifteenth-century Florentine altarpiece painted by the Pollaiuolo brothers, Antonio (1433-1498) and Piero (1443-1496), shows three saints with evident deformities of the hands and feet. The pathologies concerned are tentatively identified, and various rationales for their presence in the painting are discussed. Of particular importance is the location of the altarpiece in a chapel which houses the tomb of the Cardinal of Portugal, Prince James of Lusitania (1433-1459). It is argued that both the artistic style of the day and the religious symbolism of the Cardinal's funeral chapel contributed to the artists' decision to portray the saints with deformities. An unnatural curvature of the fifth finger was apparently considered elegant in fifteenth-century paintings, and the depiction of bare feet with hallux valgus gave them a shape which approximated and could have been caused by fashionable pointed shoes. But in addition, deformities in religious art could be symbolic of suffering and martyrdom, a theme which the Cardinal's chapel emphasised in a number of ways. It is suggested therefore that the Pollaiuolo altarpiece reconciles these two disparate factors, portraying genuine deformities in a way that was artistically stylish and symbolically meaningful.

  6. Tweeting Prayers and Communicating Grief over Michael Jackson Online

    ERIC Educational Resources Information Center

    Sanderson, Jimmy; Cheong, Pauline Hope

    2010-01-01

    Death and bereavement are human experiences that new media helps facilitate alongside creating new social grief practices that occur online. This study investigated how people's postings and tweets facilitated the communication of grief after pop music icon Michael Jackson died. Drawing on past grief research, religion, and new media studies, a…

  7. Compressive strength evolution of thermally-stressed Saint Maximin limestone.

    NASA Astrophysics Data System (ADS)

    Farquharson, J.; Griffiths, L.; Baud, P.; Wadsworth, F. B.; Heap, M. J.

    2017-12-01

    The Saint Maximin quarry (Oise, France) opened in the early 1600s, and its limestone has been used extensively as masonry stone, particularly during the classical era of Parisian architecture from the 17th century onwards. Its widespread use has been due to a combination of its regional availability, its high workability, and its aesthetic appeal. Notable buildings completed using this material include sections of the Place de la Concorde and the Louvre in Paris. More recently, however, it has seen increasing use in the construction of large private residences throughout the United States as well as extensions to private institutions such as Stanford University. For any large building, fire hazard can be a substantial concern, especially in tectonically active areas where catastrophic fires may arise following large-magnitude earthquakes. Typically, house fires burn at temperatures of around 600 °C ( 1000 F). Given the ubiquity of this geomaterial as a building stone, it is important to ascertain the influence of heating on the strength of Saint Maximin limestone (SML), and in turn the structural stability of the buildings it is used in. We performed a series of compressive tests and permeability measurements on samples of SML to determine its strength evolution in response to heating to incrementally higher temperatures. We observe that the uniaxial compressive strength of SML decreases from >12 MPa at room temperature to <7 MPa at 600 °C. The rate of strength reduction increases at elevated temperature (>400 °C). We anticipate that this substantial weakening is in part a result of thermal microcracking, whereby changes in temperature induce thermal stresses due to a mismatch in thermal expansion between the constituent grains. This mechanism is compounded by the volumetric increase of quartz through its alpha - beta transition at 573 °C, and by the thermal decomposition of calcite. To track the formation of thermal microcracks, we monitor acoustic emissions

  8. Latter-Day Saint Women and Leadership: The Influence of Their Religious Worldview

    ERIC Educational Resources Information Center

    Madsen, Susan R.

    2016-01-01

    The article examines theories, assumptions, concepts, experiences, and practices from the Latter-day Saints' (LDS, or the Mormons) religious worldview to expand existing theoretical constructs and implications of leadership development and education for women. The article elucidates LDS doctrine and culture regarding women and provides specific…

  9. A Good Time: A Conversation with C. Michael Nelson

    ERIC Educational Resources Information Center

    Zabel, Robert; Kaff, Marilyn; Teagarden, Jim

    2015-01-01

    C. Michael Nelson began his special education career as a teacher of adolescents with learning and behavior disorders. He has worked as a child psychologist and as a professor with the Department of Special Education and Rehabilitation Counseling at the University of Kentucky. He coordinated the graduate Personnel Preparation Program for Teachers…

  10. Aza-Michael Reaction for an Undergraduate Organic Chemistry Laboratory

    ERIC Educational Resources Information Center

    Nigam, Manisha; Rush, Brittney; Patel, Jay; Castillo, Raul; Dhar, Preeti

    2016-01-01

    A green, aza-Michael reaction is described that can be used to teach undergraduate students conjugate addition of nitrogen nucleophile to an a,ß-unsaturated ester. Students analyze spectral data of the product obtained from the assigned reaction to determine product structure and propose the mechanism of its formation. The experiment requires…

  11. What Works, Works Everywhere: Q&A with Michael Barber

    ERIC Educational Resources Information Center

    Crow, Tracy

    2009-01-01

    This article presents an interview with Michael Barber, a partner at McKinsey & Company, leading its global education practice. He has been working on major challenges of performance, organization, and reform in government and the public services, especially education, in the U.S., U.K., and other countries. Barber was instrumental in preparing…

  12. Michael J. Fox and his Parkinson's disease.

    PubMed

    Kempster, Peter A

    2004-01-01

    Michael J. Fox was a popular and successful film and television comic actor who developed Parkinson's disease at the age of 29 years. His recently published book, Lucky Man, structured around the story of his Parkinson's disease, is an amusing, briskly paced yet introspective memoir that covers the first 40 years of his life. Although quite anecdotal, it contains interesting observations on the preclinical phase of the disorder, evolution of motor fluctuations, and tactics for pharmacological treatment. Copyright 2003 Movement Disorder Society

  13. [An exceptional human relationship (Michael P. Kierkegaard, Søren Kierkegaard)].

    PubMed

    Jacobs, R

    1978-01-01

    There were a father and a son, Michael and Sören Kierkegaard, both highly talented, imaginitive, witty, humorous, especially interested in shrewd dialectrical dialogues respectively debates, both profound melancholy ponderers. But according to very own individuality their congeniality wasn't absolute. The father, being under a questionable rigorous opinion of sin, suffered from undeserved divine grace since early childhood. And Michael Kierkegaard made Sören anxious with the religious experience of original sin. This anxiety moved (touched or affected) the sensitive son mighty. Nevertheless he should not despair hopelessly like his unlucky father. On the contrary: Sørens incomparable melancholy, mental agony and anxiety (fear or anguish) forced the faith, existing independently of them, in a radical refining. That is why Sören Kierkegaard succeeded in sublimation of all psychological and philosophic (al) attitudes (or opinions) in the sphere of religiousness. And the result? A novel philosophy of life: Christian existentialism.

  14. Saint John's wort, an herbal inducer of the cytochrome P4503A4 isoform, may alleviate symptoms of Willis-Ekbom's disease

    PubMed Central

    Pereira, José Carlos; Pradella-Hallinan, Márcia; Alves, Rosana Cardoso

    2013-01-01

    OBJECTIVE: Certain drug classes alleviate the symptoms of Willis-Ekbom's disease, whereas others aggravate them. The pharmacological profiles of these drugs suggest that drugs that alleviate Willis-Ekbom's disease inhibit thyroid hormone activity, whereas drugs that aggravate Willis-Ekbom's disease increase thyroid hormone activity. These different effects may be secondary to the opposing actions that drugs have on the CYP4503A4 enzyme isoform. Drugs that worsen the symptoms of the Willis-Ekbom's disease inhibit the CYP4503A4 isoform, and drugs that ameliorate the symptoms induce CYP4503A4. The aim of this study is to determine whether Saint John's wort, as an inducer of the CYP4503A4 isoform, diminishes the severity of Willis-Ekbom's disease symptoms by increasing the metabolism of thyroid hormone in treated patients. METHODS: In an open-label pilot trial, we treated 21 Willis-Ekbom's disease patients with a concentrated extract of Saint John's wort at a daily dose of 300 mg over the course of three months. RESULTS: Saint John's wort reduced the severity of Willis-Ekbom's disease symptoms in 17 of the 21 patients. CONCLUSION: Results of this trial suggest that Saint John's wort may benefit some Willis-Ekbom's disease patients. However, as this trial was not placebo-controlled, the extent to which Saint John's wort is effective as a Willis-Ekbom's disease treatment will depend on future, blinded placebo-controlled studies. PMID:23778343

  15. A Comparison of Secondary Chemistry Courses and Chemistry Teacher Preparation Programs in Iowa and Saint Petersburg, Russia

    NASA Astrophysics Data System (ADS)

    Sanger, Michael J.; Brincks, Erik L.; Phelps, Amy J.; Pak, Maria S.; Lyovkin, Antony N.

    2001-09-01

    This paper, which is a result of the collaboration between the University of Northern Iowa (UNI) in Cedar Falls, Iowa, and Herzen State Pedagogical University of Russia in Saint Petersburg, compares the 7-12 chemistry courses in Iowa and Saint Petersburg and the chemistry teacher preparation programs at UNI and Herzen. Differences in the 7-12 chemistry courses include curriculum design (spiral versus layer cake), students' extracurricular activities, and access to technology in the classroom. Differences in the chemistry teacher preparation programs include the number of methods and chemistry content courses required, the number of chemistry teaching majors, the proportion of teaching majors enrolled in the different natural science programs, and the typical minors and endorsements received by these majors. Although we noted many differences in chemistry instruction between Iowa and Saint Petersburg, the secondary and college instructors still face many similar issues, which include overcoming student chemophobia, improving students' algorithmic and problem-solving skills, improving students' conceptual understanding at the particulate level, and dealing with shortages in qualified secondary science teachers.

  16. HEADSTONES OF BERNARD AND MICHAEL JODD, FATHERANDSON CIVILIANS RESPONSIBLE FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    HEADSTONES OF BERNARD AND MICHAEL JODD, FATHER-AND-SON CIVILIANS RESPONSIBLE FOR CONSTRUCTION OF BRICK PERIMETER WALL WHO DIED OF YELLOW FEVER DURING WALL CONSTRUCTION. VIEW TO WEST. - Baton Rouge National Cemetery, 220 North 19th Street, Baton Rouge, East Baton Rouge Parish, LA

  17. New Models at Lasell: Q&A with President Michael Alexander

    ERIC Educational Resources Information Center

    Harney, John O.

    2018-01-01

    The "New England Journal of Higher Education" ("NEJHE") Executive Editor John O. Harney had the chance to catch up with Lasell College President Michael Alexander about the small Newton, Massachusetts, college's plans to challenge the higher education business model. The interview is presented in this article.

  18. Michael M. May: Working toward solutions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    May, M.M.

    1993-07-01

    As part of LLNL's 40th anniversary celebration held during 1992, the six former Directors were asked to participate in a lecture series. Each of these men contributed in important ways toward making the Lawrence Livermore National Laboratory (LLNL) what it has become today. Each was asked to comment on some of the Laboratory's accomplishments, his career here, his view of the changing world, and where he sees the Laboratory going in the future. Michael M. May, LLNL's fifth Director and now a Director Emeritus, comments on a broad range of issues including arms control, nonproliferation, cooperative security, and the futuremore » role of the Laboratory.« less

  19. Enhancing the IT Infrastructure at Saint Philip's Hospital: Point-of-Care Solutions

    ERIC Educational Resources Information Center

    Naydenova, Iva; White, Bruce

    2013-01-01

    Healthcare has become a rapidly changing field. With the introduction of value-based purchasing to determine reimbursement of Medicare providers based on the quality of care in addition to outcomes in treatment, the environment is becoming ever more competitive. Saint Philip's Hospital is among the largest non-profit hospitals in the nation…

  20. Lightcurve and Rotation Period Determination for 2578 Saint- Exupery, 4297 Eichhorn, 10132 Lummelunda and (21766) 1999 RW208.

    NASA Astrophysics Data System (ADS)

    Salvaggio, Fabio; Banfi, Massimo; Marchini, Alessandro; Papini, Riccardo

    2018-04-01

    Photometric observations of the main-belt asteroids 2578 Saint-Exupery, 4297 Eichhorn, 10132 Lummelunda and (21766) 1999 RW208 performed by the authors from June to December 2017, revealed the bimodal light curves phased to 8.146 ± 0.001 h for 2578 Saint-Exupery, 4.105 ± 0.003 h for 4297 Eichhorn, 2.51 ± 0.03 h for 10132 Lummellunda and 5.841 ± 0.001 h for (21766) 1999 RW208 as the most likely solutions representing the synodic rotation periods for these asteroids.

  1. 2016 Summer Series - Michael Flynn - Synthetic Biological Membrane

    NASA Image and Video Library

    2016-08-02

    Full understanding leads to creation capability, which results in customization capacity. Synthetic biology uses our knowledge of biology to engineer novel biological devices or organisms that can perform tasks not found in nature. For Human space exploration, synthetic biology approaches will reduce risk, mass carried and increase Human reach. Michael Flynn will discuss the International Space Station (ISS) water recycling and his current work on developing a water filtration system capable of self-repair.

  2. 78 FR 2391 - CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v. Pacific Gas and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. RP13-436-000] CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v. Pacific Gas and Electric Company... Energy Regulatory Commission (FERC); CAlifornians for Renewable Energy, Inc., Michael E. Boyd, and Robert...

  3. STS-34 Pilot Michael J. McCulley uses ARRIFLEX camera equipment

    NASA Image and Video Library

    1989-04-13

    STS-34 Atlantis, Orbiter Vehicle (OV) 104, Pilot Michael J. McCulley squints while looking through ARRIFLEX camera eye piece during camera briefing at JSC. McCulley rests part of the camera on his shoulder as he operates it.

  4. Adjustable repetition-rate multiplication of optical pulses using fractional temporal Talbot effect with preceded binary intensity modulation

    NASA Astrophysics Data System (ADS)

    Xie, Qijie; Zheng, Bofang; Shu, Chester

    2017-05-01

    We demonstrate a simple approach for adjustable multiplication of optical pulses in a fiber using the temporal Talbot effect. Binary electrical patterns are used to control the multiplication factor in our approach. The input 10 GHz picosecond pulses are pedestal-free and are shaped directly from a CW laser. The pulses are then intensity modulated by different sets of binary patterns prior to entering a fiber of fixed dispersion. Tunable repetition-rate multiplication by different factors of 2, 4, and 8 have been achieved and up to 80 GHz pulse train has been experimentally generated. We also evaluate numerically the influence of the extinction ratio of the intensity modulator on the performance of the multiplied pulse train. In addition, the impact of the modulator bias on the uniformity of the output pulses has also been analyzed through simulation and experiment and a good agreement is reached. Last, we perform numerical simulation on the RF spectral characteristics of the output pulses. The insensitivity of the signal-to-subharmonic noise ratio (SSNR) to the laser linewidth shows that our multiplication scheme is highly tolerant to the incoherence of the input optical pulses.

  5. Educational Implications of Michael Fishbane's "Sacred Attunement: A Jewish Theology"

    ERIC Educational Resources Information Center

    Marom, Daniel

    2008-01-01

    This article posits Michael Fishbane's Judaic scholarship as a prime resource for Jewish education. The link between the two fields can be made through a translation of the theological underpinnings of Fishbane's insights into Judaism to educational purposes and practices. Initial work with Jewish educators on establishing this link encouraged…

  6. [The embroidery work of the lady at Saint-Anne Hospital].

    PubMed

    Thillaud, Pierre L; Postel, Jacques

    2014-01-01

    In July 1974, a 72 old woman had been a patient for forty years in Sainte-Anne Hospital, Ward C. As she had again a violent brawl with her neighbour patient, she revealed being a tremendous artist. She had been confined on account of dementia paralytica in the Mecca of malariotherapy, and passionately devoted herself to embroidery. Her fancy work was rather a matter for Jean Dubuffet's art through its perfect expression and deserved being known.

  7. 77 FR 30047 - Notice of Opportunity for Public Comment on Surplus Property Release at Michael J Smith Field...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ... Comment on Surplus Property Release at Michael J Smith Field, Beaufort, NC AGENCY: Federal Aviation... J Smith Field, be used for aeronautical purposes. DATES: Comments must be received on or before June... property at the Michael J Smith Field. The property consists of one parcel located on the north side of...

  8. Michael Faraday on the Learning of Science and Attitudes of Mind.

    ERIC Educational Resources Information Center

    Crawford, Elspeth

    1998-01-01

    Makes use of Michael Faraday's ideas on learning, focusing on his attitudes toward the unknowns of science and the development of an attitude that improves scientific decision making. This approach acknowledges that there is an inner struggle involved in facing unknowns. (DDR)

  9. ORIGINS AND GENETIC DIVERSITY OF INTRODUCED POPULATIONS OF THE PUERTO RICAN RED-EYED COQUÍ, ELEUTHERODACTYLUS ANTILLENSIS, IN SAINT CROIX (U.S. VIRGIN ISLANDS) AND PANAMÁ

    PubMed Central

    Barker, Brittany S.; Rodríguez-Robles, Javier A.

    2017-01-01

    The Red-eyed Coquí, Eleutherodactylus antillensis, is a terrestrial frog endemic to the Puerto Rican Bank (Puerto Rico and numerous islands and cays off its eastern coast), in the eastern Caribbean Sea. The species was likely introduced in Saint Croix, an island c. 100 km southeast of Puerto Rico, in the late 1930s, and in Panamá City, Panamá, in the late 1950s or early 1960s, but the source(s) of these introductions are unknown. We analyzed sequence data from one mtDNA locus and four nuDNA introns to infer the origin(s) of the Saint Croix and Panamá City populations and quantify their genetic diversity. Saint Croix and Panamanian populations do not share any haplotypes, and they cluster with different native populations, suggesting that they are derived from separate sources in the Puerto Rican Bank. Patterns of population structure trace the probable sources of E. antillensis in Saint Croix to islands off Puerto Rico’s eastern coast, which include Vieques, Culebra, Saint Thomas, Saint John, Tortola, and Virgin Gorda, and possibly to eastern Puerto Rico as well. In contrast, Panamá City E. antillensis probably originated from either western or eastern Puerto Rico. Genetic diversity in the introduced populations is similar to or lower than in populations in the species’ native range, indicating that genetic diversity has not increased in the alien frogs. Our findings may facilitate the development of preventive measures to minimize introductions of non-native amphibians in the Caribbean and Central America. PMID:28649148

  10. Saint Anthony Hospital: Infusing Developmental and Family Support Services in Community-Based Medical Practice

    ERIC Educational Resources Information Center

    Casas, Paula; Isarowong, Nucha

    2015-01-01

    Physicians affiliated with small community hospitals face numerous barriers to using developmentally oriented best practices in primary care with young children. Saint Anthony Hospital's Developmental Support Project model promotes improved developmental outcomes for children through two complementary strands of services: (a) training and…

  11. Recent Evolution of the Mont Saint-Michel Bay as seen by ALOS AVNIR-2 Data (ADEN AO 3643)

    NASA Astrophysics Data System (ADS)

    Deroin, Jean-Paul; Bilaudeau, Clelia; Deffontaines, Benoit

    2008-11-01

    The ALOS AVNIR-2 scene acquired on October 24, 2007 has been used for drawing a new map of the Mont Saint-Michel Bay. This area is characterised by a large dry-fallen tidal flat, one of the largest in the world. The tidal records indicate that the ALOS datatake was acquired in favorable conditions, the elevation of the sea at 2.56 m being very close to the theoretical minimum value (about 2.30 m). In these conditions, the largest tidal flat observed by a sun-synchronous satellite on the Mont Saint-Michel Bay is exposed.

  12. Saint, Sinner, or Soldier - Liberation Theology and Low Intensity Conflict

    DTIC Science & Technology

    1991-12-17

    wing 71 extremist. The rise of Liberation Theology in Guatemala received its momentum from the Maryknoll’s Cursillos de Capacitacion . This program...34Guatemala," pp. 312-313. 71. Summarized from Ibid, p. 313. 72. Information on the Cursillos de Capacitacion and the quote were taken from Michael

  13. Chemopreventive Agents from Physalis minima Function as Michael Reaction Acceptors

    PubMed Central

    Men, Ruizhi; Li, Ning; Ding, Chihong; Tang, Yingzhan; Xing, Yachao; Ding, Wanjing; Ma, Zhongjun

    2016-01-01

    Background: The fruits of some varieties of genus Physalis have been used as delicious fruits and functional food in the Northeast of China. Materials and Methods: To reveal the functional material basis, we performed bioactivity-guided phytochemical research and chemopreventive effect assay of the constituents from Physalis minima. Results: It was demonstrated that the ethyl acetate extract of P. minima L. (EEPM) had potential quinone reductase (QR) inducing activity with induction ratio (IR, QR induction activity) value of 1.47 ± 0.24, and glutathione binding property as potential Michael reaction acceptors (with an α, β-unsaturated ketone moiety). Furthermore, bioactivity-guided phytochemical research led eight compounds (1–8), which were elucidated as 3-isopropyl-5-acetoxycyclohexene-2-one-1 (1), isophysalin B (2), physalin G (3), physalin D (4), physalin I (5), physordinose B (6), stigmasterol-3-O-β-D-glucopyranoside (7) and 5α-6β-dihydroxyphysalin R (8) on the basis of nuclear magnetic resonance spectroscopy analyses and HRESIMS. Then, isophysalin B (2) and physordinose B (6) showed significant QR inducing activity with IR value of 2.80 ± 0.19 and 2.38 ± 0.46, respectively. SUMMARY An ultra-performance liquid chromatographic method with glutathione as the substrate was used to detect the Michael reaction acceptors in extracts of Physalis minima (EPM)We investigated the chemical constituents of EPM guided by biological activity methodIsophysalin B (1) and physordinose B (6) showed strong quinone reductase inducing activity with induction ratio values of 2.80 ± 0.19 and 2.38 ± 0.46This study generated useful information for consumers and many encourage researchers to utilize edible fruits from Physalis as a source of phytochemicals Abbreviations used: EPM: Extracts of Physalis minima, EEPM: Ethyl acetate extract of Physalis minima L., GSH: Glutathione, MRAs: Michael reaction acceptors, QR: Quinone reductase. PMID:27279713

  14. Michael Young's "The Rise of the Meritocracy": A Philosophical Critique

    ERIC Educational Resources Information Center

    Allen, Ansgar

    2011-01-01

    This paper examines Michael Young's 1958 dystopia, "The Rise of the Meritocracy". In this book, the word "meritocracy" was coined and used in a pejorative sense. Today, however, meritocracy represents a positive ideal against which we measure the justice of our institutions. This paper argues that, when read in the twenty-first century, Young's…

  15. On Happiness and High Achievement: An Interview with Michael Thompson

    ERIC Educational Resources Information Center

    National Association of Independent Schools (NAIS) (NJ), 2006

    2006-01-01

    Michael G. Thompson knows independent schools. He attended them in elementary and secondary school, and has worked in them as a psychologist. He consults with more than 30 schools a year, addressing a myriad of issues related to complex human interaction. He has written often in "Independent School" about everything from understanding the social…

  16. Passings to note: Paul Michael Packman, MD; S. Charles Schulz, MD.

    PubMed

    Black, Donald W

    2018-02-01

    One of the keys to the success of Annals of Clinical Psychiatry has always been the tireless efforts of our dedicated Editorial Board. We recently lost 2 longtime Editorial Board members, Drs. Paul Michael Packman and S. Charles Schulz. Both will be greatly missed.

  17. Saint Lawrence Seaway Navigation-Aid System Study : Volume I - Text and Appendixes A and D

    DOT National Transportation Integrated Search

    1978-09-01

    The requirements for a navigation guidance system which will effect an increase in the ship processing capacity of the Saint Lawrence Seaway (Lake Ontario to Montreal, Quebec) are developed. The requirements include a specification of system position...

  18. Shaping the Global Civil Society: An Interview with Michael Peters

    ERIC Educational Resources Information Center

    Heraud, Richard; Tesar, Marek

    2017-01-01

    Professor Michael A. Peters has worked in an era of transformation that has taken him from a labour-intensive paper-based form of production to the computerised reproduction of thought, and the current shift in the publishing landscape from a reader-subscription to an author-pays model. Most of what he has learned in publishing and editing he has…

  19. Michael E. Barnes: Award for Distinguished Professional Contributions to Institutional Practice

    ERIC Educational Resources Information Center

    American Psychologist, 2012

    2012-01-01

    Presents a short biography on the winner of the American Psychological Association's Award for Distinguished Professional Contributions to Institutional Practice. The 2012 winner is Michael E. Barnes for his pioneering leadership, dedication, and distinguished contributions to juvenile justice. As chief psychologist of the Superior Court of the…

  20. 76 FR 21406 - Michael J. Aruta, M.D.; Decision and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 10-40] Michael J. Aruta, M.D.; Decision and Order ACTION: Correction. On Thursday, April 7, 2011, the Drug Enforcement Administration published the above-titled Decision and Order, as well as the Decision of the Administrative Law Judge (76...

  1. Q & A with Ed Tech Leaders: Interview with J. Michael Spector

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.; Fulgham, Susan M.

    2015-01-01

    J. Michael Spector's academic preparation was in philosophy--epistemology and logic, primarily. His dissertation was on skepticism in modern philosophy, and that led him to a deep-seated appreciation for classical skepticism. The word "skeptic" is derived from the Greek word "skepsis," which means investigation. While the…

  2. College of Saint Teresa: Design for Choicemakers. An Operations Manual for Faculty and Staff.

    ERIC Educational Resources Information Center

    Batell, Susan; And Others

    The College of Saint Teresa's value-based educational program, known as "Design for Choicemakers," is described. The program is designed to foster students' holistic learning and personal development, based on cooperation among the academic affairs, student affairs, and pastoral affairs offices. The links between the curriculum and…

  3. The power of virtual integration: an interview with Dell Computer's Michael Dell. Interview by Joan Magretta.

    PubMed

    Dell, M

    1998-01-01

    Michael Dell started his computer company in 1984 with a simple business insight. He could bypass the dealer channel through which personal computers were then being sold and sell directly to customers, building products to order. Dell's direct model eliminated the dealer's markup and the risks associated with carrying large inventories of finished goods. In this interview, Michael Dell provides a detailed description of how his company is pushing that business model one step further, toward what he calls virtual integration. Dell is using technology and information to blur the traditional boundaries in the value chain between suppliers, manufacturers, and customers. The individual pieces of Dell's strategy--customer focus, supplier partnerships, mass customization, just-in-time manufacturing--may be all be familiar. But Michael Dell's business insight into how to combine them is highly innovative. Direct relationships with customers create valuable information, which in turn allows the company to coordinate its entire value chain back through manufacturing to product design. Dell describes how his company has come to achieve this tight coordination without the "drag effect" of ownership. Dell reaps the advantages of being vertically integrated without incurring the costs, all the while achieving the focus, agility, and speed of a virtual organization. As envisioned by Michael Dell, virtual integration may well become a new organizational model for the information age.

  4. Michael K. Scullin: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    PubMed

    2011-11-01

    Presents Michael K. Scullin as the 2011 winner of the American Psychological Association Psi Chi/APA Edwin B. Newman Graduate Research Award. "For an outstanding research paper that examines the relationship between prospective memory in executing a goal and various lapses of time from 20 minutes up to a 12- hour wake delay and a 12-hour sleep delay. The results suggest that consolidation processes active during sleep increase the probability of goal execution. The paper, titled 'Remembering to Execute a Goal: Sleep On It!' was published in Psychological Science in 2010 and was the basis for Michael K. Scullin's selection as the recipient of the 2011 Psi Chi/APA Edwin B. Newman Graduate Research Award. Mark A. McDaniel, PhD, served as faculty research advisor." (PsycINFO Database Record (c) 2011 APA, all rights reserved). 2011 APA, all rights reserved

  5. A new method for fusion, denoising and enhancement of x-ray images retrieved from Talbot-Lau grating interferometry.

    PubMed

    Scholkmann, Felix; Revol, Vincent; Kaufmann, Rolf; Baronowski, Heidrun; Kottler, Christian

    2014-03-21

    This paper introduces a new image denoising, fusion and enhancement framework for combining and optimal visualization of x-ray attenuation contrast (AC), differential phase contrast (DPC) and dark-field contrast (DFC) images retrieved from x-ray Talbot-Lau grating interferometry. The new image fusion framework comprises three steps: (i) denoising each input image (AC, DPC and DFC) through adaptive Wiener filtering, (ii) performing a two-step image fusion process based on the shift-invariant wavelet transform, i.e. first fusing the AC with the DPC image and then fusing the resulting image with the DFC image, and finally (iii) enhancing the fused image to obtain a final image using adaptive histogram equalization, adaptive sharpening and contrast optimization. Application examples are presented for two biological objects (a human tooth and a cherry) and the proposed method is compared to two recently published AC/DPC/DFC image processing techniques. In conclusion, the new framework for the processing of AC, DPC and DFC allows the most relevant features of all three images to be combined in one image while reducing the noise and enhancing adaptively the relevant image features. The newly developed framework may be used in technical and medical applications.

  6. Synthesis of pyroglutamic acid derivatives via double michael reactions of alkynones.

    PubMed

    Scansetti, Myriam; Hu, Xiangping; McDermott, Benjamin P; Lam, Hon Wai

    2007-05-24

    In the presence of substoichiometric quantities of potassium tert-butoxide and an additional metal salt, amide-tethered diacids undergo double Michael reactions with alkynones to provide highly functionalized pyroglutamic acid derivatives. The metal salt was found to play an important role in improving the diastereoselectivities of the reactions.

  7. Broadening the Debate: Comments on Michael J. Feuer's "Moderating the Debate"

    ERIC Educational Resources Information Center

    Robertson, Emily

    2009-01-01

    In "Moderating the Debate: Rationality and the Promise of American Education", Michael Feuer argues that insights from cognitive science and the theory of bounded rationality can help us understand why educational policy makers overreach in seeking optimal solutions to educational problems. In this essay, Emily Robertson argues that cognitive…

  8. History of psychosurgery at Sainte-Anne Hospital, Paris, France, through translational interactions between psychiatrists and neurosurgeons.

    PubMed

    Zanello, Marc; Pallud, Johan; Baup, Nicolas; Peeters, Sophie; Turak, Baris; Krebs, Marie Odile; Oppenheim, Catherine; Gaillard, Raphael; Devaux, Bertrand

    2017-09-01

    Sainte-Anne Hospital is the largest psychiatric hospital in Paris. Its long and fascinating history began in the 18th century. In 1952, it was at Sainte-Anne Hospital that Jean Delay and Pierre Deniker used the first neuroleptic, chlorpromazine, to cure psychiatric patients, putting an end to the expansion of psychosurgery. The Department of Neuro-psychosurgery was created in 1941. The works of successive heads of the Neurosurgery Department at Sainte-Anne Hospital summarized the history of psychosurgery in France. Pierre Puech defined psychosurgery as the necessary cooperation between neurosurgeons and psychiatrists to treat the conditions causing psychiatric symptoms, from brain tumors to mental health disorders. He reported the results of his series of 369 cases and underlined the necessity for proper follow-up and postoperative re-education, illustrating the relative caution of French neurosurgeons concerning psychosurgery. Marcel David and his assistants tried to follow their patients closely postoperatively; this resulted in numerous publications with significant follow-up and conclusions. As early as 1955, David reported intellectual degradation 2 years after prefrontal leucotomies. Jean Talairach, a psychiatrist who eventually trained as a neurosurgeon, was the first to describe anterior capsulotomy in 1949. He operated in several hospitals outside of Paris, including the Sarthe Psychiatric Hospital and the Public Institution of Mental Health in the Lille region. He developed stereotactic surgery, notably stereo-electroencephalography, for epilepsy surgery but also to treat psychiatric patients using stereotactic lesioning with radiofrequency ablation or radioactive seeds of yttrium-90. The evolution of functional neurosurgery has been marked by the development of deep brain stimulation, in particular for obsessive-compulsive disorder, replacing the former lesional stereotactic procedures. The history of Sainte-Anne Hospital's Neurosurgery Department sheds

  9. A celebration of mechanics: from nano to macro. The J. Michael T. Thompson Festschrift issue.

    PubMed

    Elishakoff, Isaac

    2013-06-28

    This Theme Issue is dedicated to the topic 'Mechanics: from nano to macro' and marks the 75th birthday of Dr J. Michael T. Thompson, Fellow of the Royal Society, whose current affiliations are as follows: (i) Honorary Fellow, Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge; (ii) Emeritus Professor of Nonlinear Dynamics, Department of Civil, Environmental and Geomatic Engineering, University College London; and (iii) Professor of Theoretical and Applied Dynamics (Distinguished Sixth Century Chair, part-time), University of Aberdeen. He also serves as Chairman of the Board of Directors at ES-Consult (consulting engineers) in Copenhagen, Denmark. The pertinent question that arises from the very start is: should we first salute Michael and then describe the Theme Issue, or vice versa? Indeed, according to Blaise Pascal (1623-1662), the last thing one discovers in composing a work is what to put first. I would like to take the liberty of deviating from the tradition of the Philosophical Transactions and start with the tribute to Michael; after all he is the prime cause of this Theme Issue.

  10. Acid-Activatable Michael-Type Fluorescent Probes for Thiols and for Labeling Lysosomes in Live Cells.

    PubMed

    Dai, Chun-Guang; Du, Xiao-Jiao; Song, Qin-Hua

    2015-12-18

    A Michael addition is usually taken as a base-catalyzed reaction. Most fluorescent probes have been designed to detect thiols in slightly alkaline solutions (pH 7-9). The sensing reactions of almost all Michael-type fluorescent probes for thiols are faster in a high pH solution than in a low pH solution. In this work, we synthesized a series of 7-substituted 2-(quinolin-2-ylmethylene)malonic acids (QMAs, substituents: NEt2, OH, H, Cl, or NO2) and their ethyl esters (QMEs) as Michael-type fluorescent probes for thiols. The sensing reactions of QMAs and QMEs occur in distinct pH ranges, pH < 7 for QMAs and pH > 7 for QMEs. On the basis of experimental and theoretic studies, we have clarified the distinct pH effects on the sensing reactivity between QMAs and QMEs and demonstrated that two QMAs (NEt2, OH) are highly sensitive and selective fluorescent probes for thiols in acidic solutions (pH < 7) and promising dyes that can label lysosomes in live cells.

  11. Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions.

    PubMed

    Jackson, Paul A; Widen, John C; Harki, Daniel A; Brummond, Kay M

    2017-02-09

    Although Michael acceptors display a potent and broad spectrum of bioactivity, they have largely been ignored in drug discovery because of their presumed indiscriminate reactivity. As such, a dearth of information exists relevant to the thiol reactivity of natural products and their analogues possessing this moiety. In the midst of recently approved acrylamide-containing drugs, it is clear that a good understanding of the hetero-Michael addition reaction and the relative reactivities of biological thiols with Michael acceptors under physiological conditions is needed for the design and use of these compounds as biological tools and potential therapeutics. This Perspective provides information that will contribute to this understanding, such as kinetics of thiol addition reactions, bioactivities, as well as steric and electronic factors that influence the electrophilicity and reversibility of Michael acceptors. This Perspective is focused on α,β-unsaturated carbonyls given their preponderance in bioactive natural products.

  12. Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions

    PubMed Central

    Jackson, Paul A.; Widen, John C.; Harki, Daniel A.; Brummond, Kay M.

    2017-01-01

    Although Michael acceptors display a potent and broad spectrum of bioactivity, they have largely been ignored in drug discovery because of their presumed indiscriminate reactivity. As such, a dearth of information exists relevant to the thiol reactivity of natural products and their analogs possessing this moiety. In the midst of recently approved acrylamide-containing drugs, it is clear that a good understanding of the hetero-Michael addition reaction and the relative reactivities of biological thiols with Michael acceptors under physiological conditions is needed for the design and use of these compounds as biological tools and potential therapeutics. This perspective provides information that will contribute to this understanding, such as kinetics of thiol addition reactions, bioactivities, as well as steric and electronic factors that influence the electrophilicity and reversibility of Michael acceptors. This perspective is focused on α,β-unsaturated carbonyls given their preponderance in bioactive natural products. PMID:27996267

  13. An Integral Part of the Frederick Community—Michael Dean | Poster

    Cancer.gov

    For more than 30 years, Michael Dean, Ph.D., has been an integral part of the NCI at Frederick community. In addition to studying several different aspects of genomics and cancer research, he has worked with the Werner H. Kirsten Student Intern Program and also volunteered his time with Mission of Mercy, a community-based organization providing free healthcare and free

  14. Baldrige Award cites two hospitals. Baptist, Saint Luke's hospitals honored for quality, performance.

    PubMed

    Rees, Tom

    2004-01-01

    Baptist Hospital Inc., Pensacola, Fla.; and Saint Luke's Hospital, Kansas City, Mo., have received the prestigious Malcolm Baldrige National Quality Award in the category of healthcare. Named for a former secretary of commerce, the award recognizes efficiency, effectiveness and excellence. The two hospitals are among only seven companies in the U.S. to be so recognized this year.

  15. New optical museum at Saint-Petersburg for education and training

    NASA Astrophysics Data System (ADS)

    Vasil'ev, V. N.; Stafeef, S. K.; Tomilin, M. G.

    2009-06-01

    Nowadays the educational problem of teaching optics and photonics is to attract the young generation to the wonderful and magic world of light, optical science, technology and systems. The main issue is to explain that in the course of last several hundred years optics has been representing the most clear world view for humanity. In fact, the optics itself is a multidisciplinary complex of independent scientific directions, and, moreover, it has always been a generator of new fields of knowledge. Besides, optics and photonics are the fields within which the most fundamental problems of today's reality are to be resolved. It is absolutely necessary to encourage our scholars in getting optics and photonics education as an alternative physical basis to gaining solely computer knowledge. The main obstacle is the poor connection between program of optical education and the real optical researches, disintegration of different branches of the optical science, the demographic situation, some problems with teaching mathematics and physics at schools, and the collision between traditional educational methods and the mentality of the new generation. In Russia the Saint-Petersburg State University of Information Technologies, Mechanics and Optics offers partial solution to these problems: the organization of a real place for interactive optical science in a form of a new museum of optics, intended for education and training, seems to be the most effective way. This was the main reason for establishing such a museum in Saint-Petersburg at the end of 2008.

  16. C. P. Snow's "The Two Cultures": Michael Polanyi's Response and Context

    ERIC Educational Resources Information Center

    Jacobs, Struan

    2011-01-01

    C. P. Snow's "The Two Cultures" controversially contrasted science and literature, suggesting that neither scientists nor literary intellectuals have much in common with, and seldom bother speaking to, the other. Responding to Snow, Michael Polanyi argued that specialization has made modern culture, not twofold but manifold. In his major work,…

  17. Facts and fiction: the death of Saint Ignatius of Loyola.

    PubMed

    Rosenman, L D

    1996-01-01

    The biography of Ignatius of Loyola, the sainted founder of the Society of Jesus (the Jesuits), ends with his death in curious circumstances. A careful search of the available sources written from the time of his death in 1556 to the present has reviewed the evidence. The evidence does not support the claims for a diagnosis that has been used for four centuries. So-called historical "facts" simply are the opinions of historians. Ignatius may have suffered from hyperparathyroidism that led to his death rather than from a cholangioportal venous fistula.

  18. Little Mosie from the Margaree: A Biography of Moses Michael Coady.

    ERIC Educational Resources Information Center

    Welton, Michael R.

    This book examines the life of the Reverend Moses Michael Coady (1890-1959), a Roman Catholic priest who led the Antigonish Movement. During the Antigonish Movement, residents of the small maritime town of Antigonish, Nova Scotia, worked to achieve a nonviolent alternative to communism and fascism and to effect the social and economic…

  19. Michael Duane after Risinghill: Rise and Fall of an Educational Celebrity

    ERIC Educational Resources Information Center

    Limond, David

    2005-01-01

    In this article an attempt is made to examine the continuing implications of the operation and closure of London's Risinghill school, a co-educational comprehensive extant from 1960 to 1965. It is suggested that Risinghill's controversial headteacher, Michael Duane (1915-1997), was an educational celebrity and folk hero amongst teachers and in…

  20. Astronaut C. Michael Foale is briefed on use of Sky Genie

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Astronaut C. Michael Foale, STS-63 mission specialist, is briefed on the use of Sky Genie device by Karin L. Porter. The device would aid in emergency egress operations aboard a troubled Space Shuttle. Porter, an employee of Rockwell International, helps train astronauts in egress procedures at JSC's Shuttle mockup and integration laboratory.

  1. Mission Specialist Michael Lopez-Alegria changes out film in camera

    NASA Image and Video Library

    1995-11-05

    STS073-335-009 (20 October-5 November 1995) --- Astronaut Michael E. Lopez-Alegria, STS-73 mission specialist, changes the film in a 35mm camera on the flight deck of the Earth-orbiting Space Shuttle Columbia. Alegria joined four other NASA astronauts and two guest researchers for almost 16-days of Earth-orbit research in support of the U.S. Microgravity Laboratory (USML-2) mission.

  2. Prayer to the Saints or the Virgin and Health among Older Mexican Americans

    ERIC Educational Resources Information Center

    Krause, Neal; Bastida, Elena

    2011-01-01

    The purpose of this study was to evaluate a conceptual model that assesses whether praying to the saints or the Virgin is associated with the health of older Mexican Americans. A survey was conducted of 1,005 older Mexican Americans (Mean age = 73.9 years; SD = 6.6 years). Data from 795 of the Catholic respondents are presented in this study. The…

  3. Ciguatera fish poisoning in an international ship crew in Saint John Canada: 2015.

    PubMed

    Muecke, C; Hamper, L; Skinner, A L; Osborne, C

    2015-11-05

    An international ship crew presented for medical care in Saint John, New Brunswick, following rapid onset of gastrointestinal and in some cases neurological and cardiac symptoms after a common fish meal. Ciguatera poisoning was identified as the cause of illness. This report describes the public health investigation and management of this incident, including collaboration between the implicated provincial and federal authorities.

  4. Ciguatera fish poisoning in an international ship crew in Saint John Canada: 2015

    PubMed Central

    Muecke, C; Hamper, L; Skinner, AL; Osborne, C

    2015-01-01

    An international ship crew presented for medical care in Saint John, New Brunswick, following rapid onset of gastrointestinal and in some cases neurological and cardiac symptoms after a common fish meal. Ciguatera poisoning was identified as the cause of illness. This report describes the public health investigation and management of this incident, including collaboration between the implicated provincial and federal authorities. PMID:29769923

  5. A second level of the Saint Petersburg skyline

    NASA Astrophysics Data System (ADS)

    Krasnopolsky, Andrey; Bolotin, Sergey

    2018-03-01

    The article considers the history of the residential development in Saint Petersburg and states corresponding landmark dates. In recent years, changes in the altitude range of the residential development are noted, the influence of this factor on the formation of the city's silhouette is assessed. Reasons for such changes are identified. Attractiveness of high-rise residential complexes for living is assessed. Conclusions are made of tendencies in further housing construction development in terms of its altitude range. It is noted that it is possible to locate multi-storied buildings in the periphery of the city, taking into account specific visual characteristics of the construction site and silhouette of erected buildings; as for central districts, strict regulations regarding the altitude range are needed.

  6. A Critical Analysis of Michael Tippett's "A Child of Our Time"

    ERIC Educational Resources Information Center

    Vallee, Jean-Sebastien

    2009-01-01

    After more than ten years of thoughtful planning, Michael Tippett (1905-1998) summed up his musical, political, spiritual and philosophical beliefs in his first oratorio, "A Child of Our Time" (1941). Representing the emergence of a new level of confidence and musical maturity for Tippett, the oratorio has become the composer's most widely known…

  7. Gulliver's Travels: Michael Moore the Explorer in "Who to Invade Next"

    ERIC Educational Resources Information Center

    Beck, Bernard

    2016-01-01

    America is identified as a nation of immigrants. These immigrants are thought to be the source of its subcultures. It is also a nation of individual explorers and inventors. Their activities are also a source of diverse subcultures. Many notable movies have made heroes of such innovators in different fields of endeavor. Michael Moore's movie…

  8. Moral Education and Education in Altruism: Two Replies to Michael Hand

    ERIC Educational Resources Information Center

    White, John

    2016-01-01

    This article is a critical discussion of two recent papers by Michael Hand on moral education. The first is his "Towards a Theory of Moral Education", published in the "Journal of Philosophy of Education" in 2014 (Volume 48, Issue 4). The second is a chapter called "Beyond Moral Education?" in an edited book of new…

  9. An Interview with Michael Horn: Blending Education for High-Octane Motivation

    ERIC Educational Resources Information Center

    Patterson, Gregory A.

    2012-01-01

    Blended learning holds the potential of improving the way we educate students and of making them more motivated. Blended education--the melding of information technology based distance learning with school attendance--is perhaps the best way to educate students for 21st century skills, says Michael Horn in a "Kappan" interview. Horn points out…

  10. A Worked Example of an Application of the Saint Simulation Program.

    DTIC Science & Technology

    1987-09-01

    tApprove foX pu bldc L-- -’ -:,=* J Approved for public release. This work is copyright. Apart from any fair dealing for the purpose of study, research...this network are 1. there are three types of incoming messages, 2. the rate of message generation is varied between two limits and is controlled by the...SAINT controlling program, and 3. the whole scenario is run for a fixed period of time itim limit). These features were included on the basis of

  11. High-rise construction in the Saint Petersburg agglomeration in 1703-1950s

    NASA Astrophysics Data System (ADS)

    Sementsov, Sergey; Akulova, Nadezhda; Kurakina, Severina

    2018-03-01

    Regularities of high-rise construction (implemented projects and developments) in Saint Petersburg and the Saint Petersburg agglomeration since the foundation of the city in 1703 till the 1950s are considered. Based on these regularities, a single spatially developed system of vertical dominants is formed. High-rise construction in the city and its suburbs started in the 1710s and continues up to the present time. In the considered decades (1703-1950s), high-rise construction mostly performed urban-planning functions (with vertical and symbolic dominants), relying on patterns of the visual perception of man-made landscapes under development. Since the 1710s, the construction of vertical dominants (mainly temples, spires of towers, lighthouses, etc.) of five ranks (depending on the altitude range and in relation to the background development) was conducted in territories of the entire agglomeration. These dominants were arranged in landscapes of the city and suburbs with almost mathematically precise accuracy and according to special regulations. Such dominants obtained particular descriptive and silhouette characteristics in accordance with the conditions of spatial perception. In some periods of city development, attempts were made to create monuments (symbolic dominants) of specific height and include those in the spatial system of high-rise dominants as significant elements of the city silhouette.

  12. Symposium on Applications and the Internet (SAINT 2003) Proceedings (Orlando, Florida, January 27-31, 2003).

    ERIC Educational Resources Information Center

    Helal, Sumi, Ed.; Oie, Yuji, Ed.; Chang, Carl, Ed.; Murai, Jun, Ed.

    This proceedings from the 2003 Symposium on Applications and the Internet (SAINT) contains papers from sessions on: (1) mobile Internet, including a target-driven cache replacement policy, context-awareness for service discovery, and XML transformation; (2) collaboration technology I, including human-network-based filtering, virtual collaboration…

  13. NASA Dryden test pilot Michael J. Adams

    NASA Image and Video Library

    1967-03-22

    Air Force test pilot Maj. Michael J. Adams stands beside X-15 ship number one. Adams was selected for the X-15 program in 1966 and made his first flight on Oct. 6, 1966. On Nov. 15, 1967, Adams made his seventh and final X-15 flight. The X-15 launched from the B-52, but during the ascent an electrical problem affected the X-15's control system. The aircraft crashed northwest of Cuddeback Lake, California, causing the death of Adams. He was posthumously awarded Air Force astronaut wings because his final flight exceeded 50 miles in altitude. Adams was the only pilot lost in the 199-flight X-15 program.

  14. PREFACE: 1st International School and Conference "Saint Petersburg OPEN 2014" on Optoelectronics, Photonics, Engineering and Nanostructures

    NASA Astrophysics Data System (ADS)

    2014-09-01

    Dear Colleagues, 1st International School and Conference "Saint Petersburg OPEN 2014" on Optoelectronics, Photonics, Engineering and Nanostructures was held on March 25 - 27, 2014 at St. Petersburg Academic University - Nanotechnology Research and Education Centre of the Russian Academy of Sciences. The School and Conference included a series of invited talks given by leading professors with the aim to introduce young scientists with actual problems and major advances in physics and technology. The keynote speakers were: Mikhail Glazov (Ioffe Physico-Technical Institute RAS, Russia) Vladimir Dubrovskii (Saint Petersburg Academic University RAS, Russia) Alexey Kavokin (University of Southampton, United Kingdom and St. Petersburg State University, Russia) Vladimir Korenev (Ioffe Physico-Technical Institute RAS, Russia) Sergey Kukushkin (Institute of Problems of Mechanical Engineering RAS, Russia) Nikita Pikhtin (Ioffe Physico-Technical Institute RAS, Russia and "Elfolum" Ltd., Russia) Dmitry Firsov (Saint Petersburg State Polytechnical University, Russia) During the poster session all undergraduate and graduate students attending the conference presented their works. Sufficiently large number of participants with more than 160 student attendees from all over the world allowed the Conference to provide a fertile ground for the fruitful discussions between the young scientists as well as to become a perfect platform for the valuable discussions between student authors and highly experienced scientists. The best student papers, which were selected by the Program Committee and by the invited speakers basing on the theses and their poster presentation, were awarded with diplomas of the conference - see the photos. This year's School and Conference is supported by SPIE (The International Society for Optics and Photonics), OSA (The Optical Society), St. Petersburg State Polytechnical University and by Skolkovo Foundation. It is a continuation of the annual schools and

  15. Q & A with Ed Tech Leaders: Interview with Michael W. Allen

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.

    2014-01-01

    Michael W. Allen, the Chairman and CEO of Allen Interactions, is an architect of interactive multimedia learning and is recognized for his many insights, inventions, and presentations. With over 50 years of experience in e-learning, both in academic and corporate settings, he is known for his role in creating Authorware and overseeing the work of…

  16. Irish Education for the 21st Century. Michael Enright Commemorative Project.

    ERIC Educational Resources Information Center

    Ward, Noel, Ed.; Dooney, Triona, Ed.

    The essays in this collection contribute to the ongoing discussion about the state of Irish education on the threshold of a new century. The various contributors examine issues that will be priorities for education planners in Ireland. These essays have been collected as a tribute to Irish educator and politician Michael Enright. The essays are:…

  17. The Benevolent Technocrat: Michael Dukakis' Strategy in the 1988 Presidential Debates.

    ERIC Educational Resources Information Center

    Herbeck, Dale A.

    Michael Dukakis lost the presidential campaign debates of 1988 (or at least failed to capitalize as much as he might have) because he understood the debates to be genuine debates. Consequently, Dukakis acted as a debater generating an image of himself as a "benevolent technocrat," which was an error. It must be pointed out that the…

  18. 3-D Perspective View, Miquelon and Saint Pierre Islands

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This image shows Miquelon and Saint Pierre Islands, located south of Newfoundland, Canada. These islands, along with five smaller islands, are a self-governing territory of France. North is in the top right corner of the image. The island of Miquelon, in the background, is divided by a thin barrier beach into Petite Miquelon on the left, and Grande Miquelon on the right. Saint Pierre Island is seen in the foreground. The maximum elevation of this land is 240 meters (787 feet). The land mass of the islands is about 242square kilometers (94 square miles) or 1.5 times the size of Washington, DC.

    This three-dimensional perspective view is one of several still photographs taken from a simulated flyover of the islands. It shows how elevation data collected by the Shuttle Radar Topography Mission (SRTM) can be used to enhance other satellite images. Color and natural shading are provided by a Landsat 7 image taken on September 7, 1999. The Landsat image was draped over the SRTM data. Terrain perspective and shading are from SRTM. The vertical scale has been increased six times to make it easier to see the small features. This also makes the sea cliffs around the edges of the islands look larger. In this view the capital city of Saint Pierre is seen as the bright area in the foreground of the island. The thin bright line seen in the water is a breakwater that offers some walled protection for the coastal city.

    Elevation data used in this image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on February 11,2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and

  19. Michael F. Vaccaro Honors Attorney Fellowship Program in our Philadelphia (Region 3) Office

    EPA Pesticide Factsheets

    The Michael F. Vaccaro Honors Attorney Fellowship provides a unique opportunity to practice law in a major governmental environmental organization, and to receive extensive training in and exposure to environmental law and policy work in the public sector.

  20. An Integral Part of the Frederick Community—Michael Dean | Poster

    Cancer.gov

    For more than 30 years, Michael Dean, Ph.D., has been an integral part of the NCI at Frederick community. In addition to studying several different aspects of genomics and cancer research, he has worked with the Werner H. Kirsten Student Intern Program and also volunteered his time with Mission of Mercy, a community-based organization providing free healthcare and free prescription medications to the uninsured and under-insured.

  1. Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents.

    PubMed

    Zheng, Suqing; Santosh Laxmi, Y R; David, Emilie; Dinkova-Kostova, Albena T; Shiavoni, Katherine H; Ren, Yanqing; Zheng, Ying; Trevino, Isaac; Bumeister, Ronald; Ojima, Iwao; Wigley, W Christian; Bliska, James B; Mierke, Dale F; Honda, Tadashi

    2012-05-24

    Novel monocyclic cyanoenones examined to date display unique features regarding chemical reactivity as Michael acceptors and biological potency. Remarkably, in some biological assays, the simple structure is more potent than pentacyclic triterpenoids (e.g., CDDO and bardoxolone methyl) and tricycles (e.g., TBE-31). Among monocyclic cyanoenones, 1 is a highly reactive Michael acceptor with thiol nucleophiles. Furthermore, an important feature of 1 is that its Michael addition is reversible. For the inhibition of NO production, 1 shows the highest potency. Notably, its potency is about three times higher than CDDO, whose methyl ester (bardoxolone methyl) is presently in phase III clinical trials. For the induction of NQO1, 1 also demonstrated the highest potency. These results suggest that the reactivity of these Michael acceptors is closely related to their biological potency. Interestingly, in LPS-stimulated macrophages, 1 causes apoptosis and inhibits secretion of TNF-α and IL-1β with potencies that are higher than those of bardoxolone methyl and TBE-31.

  2. Stray Dogs, Saints, and Saviors: Fighting for the Soul of America's Toughest High School

    ERIC Educational Resources Information Center

    Russo, Alexander

    2011-01-01

    This book tells the real-life story of Locke High School. Locke High--originally known for its excellence--became one of the toughest, most dysfunctional schools in the nation. Then in 2007 teachers voted to bring in an upstart charter school organization called "Green Dot" to try and restore the Locke Saints' past glory. It was a brave…

  3. Sex Discrimination at Saint Ambrose University: The Moral and Legal Consequences of Unethical Behavior

    ERIC Educational Resources Information Center

    Martin, Jennifer; Beese, Jane A.

    2015-01-01

    This case was developed for use in a learning-centered course with a focus on administrative leadership and ethical behavior. This case describes the experience of a new faculty member at Saint Ambrose University, as she discovers a wide range of ethical and management problems in her department. The case unfolds as we track her efforts to deal…

  4. 78 FR 9940 - Naugatuck Valley Surgical Center, Department of Saint Mary's Hospital, Waterbury, CT: Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-82,137] Naugatuck Valley Surgical Center, Department of Saint Mary's Hospital, Waterbury, CT: Notice of Affirmative Determination... application, I conclude that the claim is of sufficient weight to justify reconsideration of the U.S...

  5. Nure aerial gamma-ray and magnetic reconnaissance survey: Chugach/Yakutat area, Alaska, Mt. Saint Elias Quadrangle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1978-10-01

    Volume II contains the following data on Mt. Saint Elias, Alaska: geologic base map, flight path map, anomaly maps (U, Th, K, UlTh, UlK, ThlK), radiometric multiple-parameter stacked profiles, magnetic and ancillary profile data, and statistical data. (LK)

  6. Theory and practice in action: the contributions of Michael Perkins to clinical linguistics.

    PubMed

    Damico, Jack S; Lynch, Karen E

    2013-01-01

    This article reviews the scholarly contributions of Michael R. Perkins in the discipline of clinical linguistics and provides some indication of the reasons that he has been so successful. Three primary attributes were described through an analysis of his publications.

  7. From Gouldner to Gramsci: The Making of Michael Apple's "Ideology and Curriculum"

    ERIC Educational Resources Information Center

    Gottesman, Isaac

    2012-01-01

    Michael Apple's "Ideology and Curriculum", published in 1979, helped initiate a broad turn in the field of education in the United States to Marxist thought as a lens through which to analyze the relationship between school and society. This classic text continues to inform scholarship in the field. While "Ideology" has…

  8. Great artists with rheumatoid arthritis. What did their disease and coping teach? Part II. Raoul Dufy and Niki de Saint Phalle.

    PubMed

    Zeidler, Henning

    2012-12-01

    Raoul Dufy (1877-1953) and Niki de Saint Phalle (1930-2002) were 2 famous artists who suffered from rheumatoid arthritis (RA). Both artists represent an additional outstanding example of successful coping with RA in former times when, for the first time, corticosteroids were available, but nevertheless treatment was very limited in the pre-biological era. Dufy was one of the earliest patients with RA who received corticosteroids and regained his creativity to paint for a few additional years, but finally he died of massive intestinal hemorrhages, the adverse event of the combination of corticosteroid plus aspirin. Niki de Saint Phalle, a self-taught French painter and sculptor, was one of the most significant and unconventional female artists of the 20th century. Her eventful life was full of emotional burdens and lifelong lung disease in addition to RA. Niki de Saint Phalle came out from each physical and emotional crisis with new forces and new artistic ideas. Interestingly, it has been suggested that the occupational exposure to colors contributed to the development of RA in artists, which used significantly more bright and clear colors based on toxic heavy metals such as Renoir and Dufy. Moreover, these 2 were cigarette smokers, a recently described risk factor for developing RA and increasing the severity once it does develop. Niki de Saint Phalle produced her sculptures made of plastic material without protection while she assumed that exposition to polyester and toxic fumes of polystyrene caused severe damage to her lungs, resulting in recurrent health problems.

  9. Center for Transportation Studies 24th annual transportation research conference, May 22-23, 2013, Saint Paul, Minnesota.

    DOT National Transportation Integrated Search

    2013-05-01

    The University of Minnesotas Center for Transportation : Studies is pleased to present its 24th Annual Transportation : Research Conference, May 22-23, 2013. The conference will : be held at the Saint Paul RiverCentre, 175 West Kellogg : Boulevard...

  10. A Comparative Case Study of Self-Actualization in Eleanor Roosevelt and Antoine de Saint-Exupery.

    ERIC Educational Resources Information Center

    Tyska, Cynthia Ann

    Eleanor Roosevelt and Antoine de Saint-Exupery are described as strongly developed self-actualizing people. They were selected as subjects of this study because they are generally believed to possess self-actualizing characteristics and because their positions as public figures made it more likely that data on them would be accessible.…

  11. Highlighting High Performance: Michael E. Capuano Early Childhood Center; Somerville, Massachusetts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    2006-03-01

    This brochure describes the key high-performance building features of the Michael E. Capuano Early Childhood Center. The brochure was paid for by the Massachusetts Technology Collaborative as part of their Green Schools Initiative. High-performance features described are daylighting and energy-efficient lighting, indoor air quality, solar and wind energy, building envelope, heating and cooling systems, water conservation, and acoustics. Energy cost savings are also discussed.

  12. A tribute to Michael R. Raupach for contributions to aeolian fluid dynamics

    USDA-ARS?s Scientific Manuscript database

    Since the early work of Bagnold in the 1940s, aeolian research has grown to become a major integral part of earth-system studies. Many individuals have contributed to this development, and Dr. Michael R. Raupach (MR2, 1950 – 2015) was one of the most outstanding. MR2 worked for about a decade (1985 ...

  13. Project Early Kindergarten Evaluation: Results through 2009-10 of a Saint Paul Public Schools Initiative

    ERIC Educational Resources Information Center

    Maxfield, Jennifer; Gozali-Lee, Edith; Mueller, Dan

    2010-01-01

    Project Early Kindergarten (PEK) aims to improve the school-readiness of Saint Paul children and help close the achievement gap through offering high-quality educational experiences for preschool children. This report comes at the conclusion of the sixth year of PEK. Following an initial planning year (2004-05), PEK has served children through the…

  14. Intrauterine contraception in Saint Louis: A Survey of Obstetrician and Gynecologists’ knowledge and attitudes

    PubMed Central

    Madden, Tessa; Allsworth, Jenifer E.; Hladky, Katherine J.; Secura, Gina M.; Peipert, Jeffrey F.

    2009-01-01

    Background Many obstacles to intrauterine contraception use exist, including provider and patient misinformation, high upfront cost, and clinician practice patterns. The aim of our study was to investigate knowledge and attitudes about intrauterine contraception among obstetricians and gynecologists in the area of Saint Louis. Study Design We mailed a self-administered, anonymous survey to 250 clinicians who provide obstetric and gynecologic care in Saint Louis City and County which included questions about demographics, training, family planning visits, and intrauterine contraceptive knowledge and use. Results The overall survey response rate among eligible clinicians was 73.7%. Clinicians who had recently finished training or saw higher numbers of contraceptive patients per week were more likely to insert intrauterine contraception than clinicians who completed training prior to 1989 or saw fewer contraceptive patients. Several misconceptions among clinicians were identified, including an association between intrauterine contraceptives and an elevated risk of pelvic inflammatory disease. Conclusions Physician misconceptions about the risks of intrauterine contraception continue to occur. Improved clinician education is greatly needed to facilitate the use of these highly effective, long-acting, reversible methods of contraception. PMID:20103447

  15. Schools as "Poetry-Friendly Places": Michael Rosen on Poetry in the Curriculum

    ERIC Educational Resources Information Center

    Xerri, Daniel

    2014-01-01

    This article explores the views of children's poet Michael Rosen in relation to poetry in education. It is based on an interview in which Rosen not only discusses the significance of encouraging young people to engage with poetry at school but also analyzes a number of threats to poetry's place in the English curriculum. This article identifies…

  16. jsc2017e009735

    NASA Image and Video Library

    2017-01-26

    jsc2017e009735 (01/26/2017) --- Former NFL players on tour of the Johnson Space Center (JSC) as part of the Centers Super Bowl tailgate event gathered together in front of JSC's Mission Control. The former players toured JSC in the week before the Super Bowl game. Kneeling front left: Kerry Henderson (NY Jets), Joe Wesley (49ers, Jaguars), First standing row, left: Ronald Humphrey (IN Colts), James Williams (Saints, Jag, 49ers, Browns), Emanuel McNeil (NY Jets), Sammy Davis (Chargers, 49ers, Buccaneers), Daryl Gaines (KC Chiefs, Cris Calloway (Giants, Steelers, Falcons, Patriots), Lemanual Stinson (Bears & Falcons). Back row left: Ginger Kerrrick (JSC Staff), Jermaine Fazonde (Chargers), Michael Holmes (49ers), Kevin Williams (Vikings, Seahawks, Saints). NASA PHOTOGRAPHER: Lauren Harnett

  17. "The Glory of God Is Intelligence": Exploring the Foundations of Latter-Day Saint Religious Education

    ERIC Educational Resources Information Center

    Griffiths, Casey Paul; Esplin, Scott C.; Randall, E. Vance

    2016-01-01

    In recent years the educational programs of the Church of Jesus Christ of Latter-day Saints (LDS) have received praise for their role in the high rates of religiosity and denominational retention among their youth. This study offers a historical summary of the efforts of LDS to develop the most effective methods of engaging their youth in…

  18. Saint Mary's College Teacher Science Institute: Converting Teachers to Using Guided Inquiry for Science Curricula

    ERIC Educational Resources Information Center

    McCarthy, Deborah; Bellina, Joseph J., Jr.

    2003-01-01

    In 1988 Saint Mary's College received a grant from Lilly Endowment, Inc. to create a program to improve the quality of science education in the local public and private schools. As part of applying that grant we created one-week summer work-shops for elementary and middle school teachers (K-8) based on guided inquiry methods of education. Each…

  19. Michael Maier--nine newly discovered letters.

    PubMed

    Lenke, Nils; Roudet, Nicolas; Tilton, Hereward

    2014-02-01

    The authors provide a transcription, translation, and evaluation of nine newly discovered letters from the alchemist Michael Maier (1568-1622) to Gebhardt Johann von Alvensleben (1576-1631), a noble landholder in the vicinity of Magdeburg. Stemming from the final year of his life, this correspondence casts new light on Maier's biography, detailing his efforts to secure patronage amid the financial crisis of the early Thirty Years' War. While his ill-fated quest to perfect potable gold continued to form the central focus of his patronage suits, Maier also offered his services in several arts that he had condemned in his printed works, namely astrology and "supernatural" magic. Remarks concerning his previously unknown acquaintance with Heinrich Khunrath call for a re-evaluation of Maier's negotiation of the discursive boundaries between Lutheran orthodoxy and Paracelsianism. The letters also reveal Maier's substantial contribution to a work previously ascribed solely to the English alchemist Francis Anthony.

  20. STS-69 MS Michael L. Gernhardt greets his mother at SLF

    NASA Technical Reports Server (NTRS)

    1995-01-01

    STS-69 Mission Specialist Michael L. Gernhardt (right) gets a chance to say hi to his mother, Suzanne Winters, and her husband Doug, after the STS-69 flight crew arrived at KSC's Shuttle Landing Facility. The five astronauts assigned to the mission are looking forward to a liftoff aboard the Space Shuttle Endeavour during a two and a half hour window opening at 11:09 a.m. EDT, Sept. 7.

  1. The Politics of Education Revisited: Anthony Crosland and Michael Gove in Historical Perspective

    ERIC Educational Resources Information Center

    Finn, Mike

    2015-01-01

    This article traces continuity and change in the governance of British education through the comparison of two ministers, Anthony Crosland and Michael Gove. Taking Maurice Kogan's seminal "The Politics of Education" as the point of departure, the article highlights the role of political ideology in large-scale educational change, taking…

  2. Neuroscientific Investigator of High Mathematical Ability: An Interview with Michael W. O'Boyle

    ERIC Educational Resources Information Center

    Kalbfleisch, M. Layne

    2008-01-01

    This article presents an interview with Michael W. O'Boyle, a neuroscientific investigator of high mathematical ability. O'Boyle is a professor in the Department of Human Development and Family Studies, Texas Tech University, and Adjunct Professor of Pharmacology and Neuroscience, School of Medicine, Texas Tech University Health Sciences Center.…

  3. Toward a Global Vision of Gifted Education: An Interview with Michael S. Matthews

    ERIC Educational Resources Information Center

    Henshon, Suzanna E.

    2017-01-01

    Dr. Michael S. Matthews is professor and director of the Academically & Intellectually Gifted graduate programs at the University of North Carolina at Charlotte. He is incoming Coeditor of the "Gifted Child Quarterly" and a member of the Board of Directors of the National Association for Gifted Children. Dr. Matthews also currently…

  4. The Journey Is the Film Is the Journey: Michael Winterbottom's "In This World"

    ERIC Educational Resources Information Center

    Farrier, David

    2008-01-01

    This essay examines Michael Winterbottom's 2002 film "In This World," which follows the journey of two Afghan migrants from Peshawar to London. Winterbottom's preparation involved travelling from London to Peshawar and then in reverse overland as far as Istanbul; he then returned to Peshawar and filmed the same journey using two…

  5. Geologic map of the Wrangell-Saint Elias National Park and Reserve, Alaska

    USGS Publications Warehouse

    Richter, Donald H.; Preller, Cindi C.; Labay, Keith A.; Shew, Nora B.

    2006-01-01

    Wrangell-Saint Elias National Park and Preserve, the largest national park within the U.S. National Park Service system, extends from the northern Pacific Ocean to beyond the eastern Alaska Range into interior Alaska. It features impressively spectacular scenery such as high and craggy mountains, active and ancient volcanoes, expansive ice fields, immense tidewater glaciers, and a myriad of alpine glaciers. The park also includes the famous Kennecott Mine, a world-class copper deposit that was mined from 1911 to 1938, and remnant ghost town, which is now a National Historic Landmark. Geologic investigations encompassing Wrangell-Saint Elias National Park and Preserve began in 1796, with Dmitriv Tarkhanov, a Russian mining engineer, who unsuccessfully ventured up the Copper River in search of rumored copper. Lieutenant H.T. Allen (1897) of the U.S. Army made a successful epic summer journey with a limited military crew up the Copper River in 1885, across the Alaska Range, and down the Tanana and Yukon Rivers. Allen?s crew was supported by a prospector named John Bremner and local Eyak and Ahtna native guides whose tribes controlled access into the Copper River basin. Allen witnessed the Ahtnas? many uses of the native copper. His stories about the copper prompted prospectors to return to this area in search of the rich copper ore in the years following his journey. The region boasts a rich mining and exploration history prior to becoming a park in 1980. Several U.S. Geological Survey geologists have conducted reconnaissance surveys in the area since Allen?s explorations. This map is the result of their work and is enhanced by more detailed investigations, which began in the late 1950s and are still continuing. For a better understanding of the processes that have shaped the geology of the park and a history of the geologic investigations in the area, we recommend U.S. Geological Survey Professional Paper 1616, ?A Geologic Guide to Wrangell-Saint Elias National Park

  6. Effects of Protection and Sediment Stress on Coral Reefs in Saint Lucia

    PubMed Central

    Bégin, Chantale; Schelten, Christiane K.; Nugues, Maggy M.; Hawkins, Julie; Roberts, Callum; Côté, Isabelle M.

    2016-01-01

    The extent to which Marine Protected Areas (MPAs) benefit corals is contentious. On one hand, MPAs could enhance coral growth and survival through increases in herbivory within their borders; on the other, they are unlikely to prevent disturbances, such as terrestrial runoff, that originate outside their boundaries. We examined the effect of spatial protection and terrestrial sediment on the benthic composition of coral reefs in Saint Lucia. In 2011 (10 to 16 years after MPAs were created), we resurveyed 21 reefs that had been surveyed in 2001 and analyzed current benthic assemblages as well as changes in benthic cover over that decade in relation to protection status, terrestrial sediment influence (measured as the proportion of terrigenous material in reef-associated sediment) and depth. The cover of all benthic biotic components has changed significantly over the decade, including a decline in coral and increase in macroalgae. Protection status was not a significant predictor of either current benthic composition or changes in composition, but current cover and change in cover of several components were related to terrigenous content of sediment deposited recently. Sites with a higher proportion of terrigenous sediment had lower current coral cover, higher macroalgal cover and greater coral declines. Our results suggest that terrestrial sediment is an important factor in the recent degradation of coral reefs in Saint Lucia and that the current MPA network should be complemented by measures to reduce runoff from land. PMID:26845451

  7. Effects of Protection and Sediment Stress on Coral Reefs in Saint Lucia.

    PubMed

    Bégin, Chantale; Schelten, Christiane K; Nugues, Maggy M; Hawkins, Julie; Roberts, Callum; Côté, Isabelle M

    2016-01-01

    The extent to which Marine Protected Areas (MPAs) benefit corals is contentious. On one hand, MPAs could enhance coral growth and survival through increases in herbivory within their borders; on the other, they are unlikely to prevent disturbances, such as terrestrial runoff, that originate outside their boundaries. We examined the effect of spatial protection and terrestrial sediment on the benthic composition of coral reefs in Saint Lucia. In 2011 (10 to 16 years after MPAs were created), we resurveyed 21 reefs that had been surveyed in 2001 and analyzed current benthic assemblages as well as changes in benthic cover over that decade in relation to protection status, terrestrial sediment influence (measured as the proportion of terrigenous material in reef-associated sediment) and depth. The cover of all benthic biotic components has changed significantly over the decade, including a decline in coral and increase in macroalgae. Protection status was not a significant predictor of either current benthic composition or changes in composition, but current cover and change in cover of several components were related to terrigenous content of sediment deposited recently. Sites with a higher proportion of terrigenous sediment had lower current coral cover, higher macroalgal cover and greater coral declines. Our results suggest that terrestrial sediment is an important factor in the recent degradation of coral reefs in Saint Lucia and that the current MPA network should be complemented by measures to reduce runoff from land.

  8. 77 FR 42672 - Radio Broadcasting Services; Alberton, MT; Crystal Falls, MI; Saint Paul, AR; and Waitsburg, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-20

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [MB Docket No. 12-115; DA 12-1084] Radio Broadcasting Services; Alberton, MT; Crystal Falls, MI; Saint Paul, AR; and Waitsburg, WA AGENCY: Federal Communications Commission. ACTION: Final rule. SUMMARY: The Audio Division, on its own motion, deletes four...

  9. 77 FR 31682 - In the Matter of Quintek Technologies, Inc., The Saint James Co., Urigen Pharmaceuticals, Inc...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-29

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] In the Matter of Quintek Technologies, Inc., The Saint James Co., Urigen Pharmaceuticals, Inc., Valor Energy Corp., Wherify Wireless, Inc., and Win... Quintek Technologies, Inc. because it has not filed any periodic reports since the period ended September...

  10. Saint-Gaudens National Historic Site: Home of a Gilded Age Icon. Teaching with Historic Places.

    ERIC Educational Resources Information Center

    Percoco, James A.

    Augustus Saint-Gaudens (1848-1907) was a renowned 19th-century U.S. sculptor whose artistic training and talent ensured his place in Gilded Age society. In 1885, he was drawn to Cornish, New Hampshire, to find a place where he could model his latest commission, a statue of Abraham Lincoln. He and his wife established a summer home and studio in an…

  11. 3-D perspective of Saint Pierre and Miquelon Islands

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This image shows two islands, Miquelon and Saint Pierre, located south of Newfoundland, Canada. These islands, along with five smaller islands, are a self-governing territory of France. A thin barrier beach divides Miquelon, with Grande Miquelon to the north and Petite Miquelon to the south. Saint Pierre Island is located to the lower right. With the islands' location in the north Atlantic Ocean and their deep water ports, fishing is the major part of the economy. The maximum elevation of the island is 240 meters (787 feet). The land mass of the islands is about 242 square kilometers, or 1.5 times the size of Washington DC.

    This image shows how data collected by the Shuttle Radar Topography Mission (SRTM) can be used to enhance other satellite images. Color and natural shading are provided by a Landsat 7 image acquired on September 1, 1999. Terrain perspective and shading were derived from SRTM elevation data acquired on February 12, 2000. Topography is exaggerated by about six times vertically. The United States Geological Survey's Earth Resources Observations Systems (EROS) DataCenter, Sioux Falls, South Dakota, provided the Landsat data.

    Elevation data used in this image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on February 11,2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between the National Aeronautics and Space Administration (NASA), the National Imagery and Mapping Agency (NIMA) of the U.S. Department of Defense (DoD), and the German and Italian space agencies

  12. Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418.

    PubMed

    Maucher, Isabelle V; Rühl, Michael; Kretschmer, Simon B M; Hofmann, Bettina; Kühn, Benjamin; Fettel, Jasmin; Vogel, Anja; Flügel, Karsten T; Manolikakes, Georg; Hellmuth, Nadine; Häfner, Ann-Kathrin; Golghalyani, Vahid; Ball, Ann-Katrin; Piesche, Matthias; Matrone, Carmela; Geisslinger, Gerd; Parnham, Michael J; Karas, Michael; Steinhilber, Dieter; Roos, Jessica; Maier, Thorsten J

    2017-02-01

    Recently, we published that nitro-fatty acids (NFA) are potent electrophilic molecules which inhibit 5-lipoxygenase (5-LO) by interacting catalytically with cysteine residues next to a substrate entry channel. The electrophilicity is derived from an intramolecular Michael acceptor moiety consisting of an electron-withdrawing group in close proximity to a double bond. The potential of the Michael acceptor moiety to interact with functionally relevant cysteines of proteins potentially renders them effective and sustained enzyme activity modulators. We screened a large library of naturally derived and synthetic electrophilic compounds to investigate whether other types of Michael acceptor containing drugs suppress 5-LO enzyme activity. The activity was measured by assessing the effect on the 5-LO product formation of intact human polymorphonuclear leukocytes. We demonstrated that a number of structurally different compounds were suppressive in the activity assays and showed that Michael acceptors of the quinone and nitro-alkene group produced the strongest inhibition of 5-LO product formation. Reactivity with the catalytically relevant cysteines 416 and 418 was confirmed using mutated recombinant 5-LO and mass spectrometric analysis (MALDI-MS). In the present study, we show for the first time that a number of well-recognized naturally occurring or synthetic anti-inflammatory compounds carrying a Michael acceptor, such as thymoquinone (TQ), the paracetamol metabolite NAPQI, the 5-LO inhibitor AA-861, and bardoxolone methyl (also known as RTA 402 or CDDO-methyl ester) are direct covalent 5-LO enzyme inhibitors that target the catalytically relevant cysteines 416 and 418. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. What Work Do the Concepts of "Language" and "Literature" Do for Michael Rosenak?

    ERIC Educational Resources Information Center

    Levisohn, Jon A.

    2014-01-01

    Michael Rosenak uses the twin metaphors of "language" and "literature," borrowed from Oakeshott and Peters, to argue that the goal of education is initiation into a language. This goal transcends the study of literature in that language. It includes, as well, the development of the capacity both to critique literature and to…

  14. Subjectivity and Cultural Adjustment in Mathematics Education: A Response to Wolff-Michael Roth

    ERIC Educational Resources Information Center

    Brown, Tony

    2012-01-01

    In this volume, Wolff-Michael Roth provides a critical but partial reading of Tony Brown's book "Mathematics Education and Subjectivity". The reading contrasts Brown's approach with Roth's own conception of subjectivity as derived from the work of Vygotsky, in which Roth aims to "reunite" psychology and sociology. Brown's book, however, focuses on…

  15. Pedagogy of the Spirit: Comparing Evangelical and Latter-Day Saint Youth Self-Reported In-Class Spiritual Experiences

    ERIC Educational Resources Information Center

    Wong, Arch Chee Keen; Sweat, Anthony; Gardner, Ryan

    2017-01-01

    This study statistically analyzes data from 756 evangelical and Latter-day Saint youth regarding their perceived in-class spiritual experiences of twenty items related to Christian theology. The data indicates similar spiritual outcomes between the two groups, with no statistically significant differences between eleven of the twenty spiritual…

  16. Development of a Fragment-Based in Silico Profiler for Michael Addition Thiol Reactivity.

    PubMed

    Ebbrell, David J; Madden, Judith C; Cronin, Mark T D; Schultz, Terry W; Enoch, Steven J

    2016-06-20

    The Adverse Outcome Pathway (AOP) paradigm details the existing knowledge that links the initial interaction between a chemical and a biological system, termed the molecular initiating event (MIE), through a series of intermediate events, to an adverse effect. An important example of a well-defined MIE is the formation of a covalent bond between a biological nucleophile and an electrophilic compound. This particular MIE has been associated with various toxicological end points such as acute aquatic toxicity, skin sensitization, and respiratory sensitization. This study has investigated the calculated parameters that are required to predict the rate of chemical bond formation (reactivity) of a dataset of Michael acceptors. Reactivity of these compounds toward glutathione was predicted using a combination of a calculated activation energy value (Eact, calculated using density functional theory (DFT) calculation at the B3YLP/6-31G+(d) level of theory, and solvent-accessible surface area values (SAS) at the α carbon. To further develop the method, a fragment-based algorithm was developed enabling the reactivity to be predicted for Michael acceptors without the need to perform the time-consuming DFT calculations. Results showed the developed fragment method was successful in predicting the reactivity of the Michael acceptors excluding two sets of chemicals: volatile esters with an extended substituent at the β-carbon and chemicals containing a conjugated benzene ring as part of the polarizing group. Additionally the study also demonstrated the ease with which the approach can be extended to other chemical classes by the calculation of additional fragments and their associated Eact and SAS values. The resulting method is likely to be of use in regulatory toxicology tools where an understanding of covalent bond formation as a potential MIE is important within the AOP paradigm.

  17. A Response to Michael W. Apple's "Theory, Research, and the Critical Scholar/Activist"

    ERIC Educational Resources Information Center

    Leonardo, Zeus

    2010-01-01

    Michael Apple's prescient review of Anyon et al.'s "Theory and Educational Research" reminds the educational community of the importance of purpose. In his own work, he has been consistent in--actually, insistent on--emphasizing the struggle over political projects. This is not an issue concerning only the Left as the scapegoat for the disparaging…

  18. N719 dye-sensitized organophotocatalysis: enantioselective tandem Michael addition/oxyamination of aldehydes.

    PubMed

    Yoon, Hyo-Sang; Ho, Xuan-Huong; Jang, Jiyeon; Lee, Hwa-Jung; Kim, Seung-Joo; Jang, Hye-Young

    2012-07-06

    A remarkably efficient photosensitizer, N719 dye, was used in asymmetric tandem Michael addition/oxyamination of aldehydes, rendering α,β-substituted aldehydes in good yields with excellent levels of enantioselectivity and diastereoselectivity. This is the first report of a multiorganocatalytic reaction involving iminium catalysis and photoinduced singly occupied molecular orbital (SOMO) catalysis. This reaction is expected to expand the scope of tandem organocatalytic reactions.

  19. [The problem of evil in families--the filmmaker Michael Haneke].

    PubMed

    Skårderud, Finn

    2010-09-23

    With the beautiful and dark film "The white ribbon", from 2009, the Austrian film director Michael Haneke consolidated his status as an international success. A central theme in his films is evilness and its roots. But just as important is his ambition to develop films where evil is not only portrayed, but where spectators are challenged to relate to their own ethical standards and their role as spectators. Haneke is a highly original filmmaker with his consistent search for a film aesthetic that stimulates ethical self-reflection and mentalizing. He partly succeeds in this quest.

  20. [Three centuries with the Fleet (to the 300th anniversary of the Saint-Petersburg naval hospital)].

    PubMed

    Buzov, E Ya; Kasatkin, V I; Makarenko, B G; Shilov, S A

    2015-09-01

    The authors analysed the history of the Saint-Petersburg naval hospital, founded in October, 1715 by Peter the Great, defined its role in the key historical events during organisation of medical, aid delivery to wounded and patients, discussed current tasks, concerning development of hospital art when forming modern image of the navy of the Russian Federation.

  1. Training and Mastery of Techniques in Wittgenstein's Later Philosophy: A Response to Michael Luntley

    ERIC Educational Resources Information Center

    Stickney, Jeff

    2008-01-01

    Responding to Michael Luntley's article, "Learning, Empowerment and Judgement," the author shows he cannot successfully make the following three moves: (1) dissolve the analytic distinction between learning by training and learning by reasoning, while advocating the latter; (2) diminish the role of training in Wittgenstein's philosophy, nor…

  2. The first leg transplant for the treatment of a cancer by Saints Cosmas and Damian.

    PubMed

    Androutsos, G; Diamantis, A; Vladimiros, L

    2008-01-01

    The most renowned of all medically inclined saints must have been St. Cosmas and St. Damian. They became the special patrons of surgery, due to their miraculous operations. On one occasion, they amputated a cancerous leg and replaced it with another, taken from a Moor who had just died. This dramatic cure was meat and drink for artists, and has been portrayed many times.

  3. The Data on Children's Media Use: An Interview with Michael Robb

    ERIC Educational Resources Information Center

    Heller, Rafael

    2018-01-01

    Since 2003, nonprofit organization Common Sense Media has studied the ways in which kids are growing up in the digital age. In this interview, research director Michael Robb shares recent findings about the media habits of young children, tweens, and teens. While the news coverage of these issues tends to be hyperbolic and alarming, Robb explains,…

  4. Situation Awareness: Papers and Annotated Bibliography

    DTIC Science & Technology

    1994-06-01

    identification 133. McKinley, R.L., Erikson , M.A., and D’Angelo, W.R. (1994). 3-Dimensional auditory displays: Development , applications, and...constructed. The second paper, by Dr. Michael Vidulich, was originally written during the early stages of the SAINT team’s response to SA concerns raised...refers to how SA is developed and maintained during flight, while the product is the resultant, elusive thing we call SA itself (Tenney, Adams, Pew

  5. Le role du phytoplancton de petite taille (<20 mum) dans les variations des proprietes optiques des eaux du Saint-Laurent

    NASA Astrophysics Data System (ADS)

    Mas, Sebastien

    Les mesures satellitaires de couleur des oceans sont largement determinees par les proprietes optiques inherentes (IOPs) des eaux de surface. D'autre part, le phytoplancton de petite taille (<20 mum) est le plus souvent dominant dans les oceans, et peut donc etre une source importante de variation des IOPs dans les oceans. Dans ce contexte, le but principal de ce doctorat etait de definir l'impact du phytoplancton (<20 mum) sur les variations des proprietes optiques de l'Estuaire et du Golfe du Saint-Laurent (Canada). Afin d'atteindre cet objectif, il etait necessaire de determiner en milieu controle les facteurs de variabilite des proprietes optiques cellulaires et des IOPs du phytoplancton (<20 mum) des eaux du Saint-Laurent, et d'evaluer la contribution du phytoplancton (<20 mum) aux proprietes optiques totales des eaux du Saint-Laurent. Des experiences en laboratoire ont montre que les variations des proprietes optiques des cellules phytoplanctoniques soumises a un cycle jour-nuit, ainsi qu'a des changements concomitants d'intensite lumineuse, peuvent contribuer significativement a la variabilite des proprietes optiques observee en milieu naturel. D'autres experiences ont, quant a elles, mis en evidence que les variations des proprietes optiques des cellules phytoplanctoniques dues aux phases de croissance peuvent alterer les IOPs des oceans, particulierement pendant les periodes de floraison. De plus, la presence de bacteries et de particules detritiques peut egalement affecter la variabilite des IOPs totales, notamment la diffusion. Au printemps, dans l'Estuaire et le Golfe du Saint-Laurent, la contribution du phytoplancton <20 mum aux IOPs presentait des differences regionales evidentes pour les proprietes d'absorption et de diffusion. En plus de la variabilite spatiale, les proprietes optiques cellulaires presentaient des variations journalieres, et ce particulierement pour le picophytoplancton. Enfin, la plupart des differences observees dans les

  6. The Educational Philosophies of Mordecai Kaplan and Michael Rosenak: Surprising Similarities and Illuminating Differences

    ERIC Educational Resources Information Center

    Schein, Jeffrey; Caplan, Eric

    2014-01-01

    The thoughts of Mordecai Kaplan and Michael Rosenak present surprising commonalities as well as illuminating differences. Similarities include the perception that Judaism and Jewish education are in crisis, the belief that Jewish peoplehood must include commitment to meaningful content, the need for teachers to teach from a position of…

  7. Obituary: Michael John Klein, 1940-2005

    NASA Astrophysics Data System (ADS)

    Gulkis, Samuel

    2006-12-01

    Michael John Klein died on 14 May 2005 at home in South Pasadena, California. The cause of death was tongue cancer that metastasized to the lungs. He was a non-smoker. Mike was a passionate radio astronomer, a trusted astronomical observer, an educator and a family man. Mike was born on 19 January 1940 in Ames, Iowa, the son of Florence Marie (Graf) and Fred Michael Klein. His mother was a homemaker, and his father was a banker. Mike had two older sisters, Lois Jean (Klein) Flauher and Marilyn June (Klein) Griffin. In 1962, Mike married his high school sweetheart Barbara Dahlberg, who survives him along with their three children, Kristin Marie (Klein) Shields, Michael John Klein Jr., Timothy Joel Klein, and six grandchildren. Mike developed a love for astronomy early in his life, and credited an early morning, newspaper-delivery route that he had at age twelve, which took him outside well before sunrise. He told family members that as he walked along his route, he stared into the sky and wondered what everything was. He studied sky charts, located stars, and began to understand how the planets shifted their positions relative to the stars each day. Another big influence in Mike's life was his brother in-law, Jim Griffin. Jim helped Mike understand that his passion for science did not have to remain a hobby, but could and should become a career. Jim's encouragement led Mike to attend Iowa State University in Ames, where he earned a BS in electrical engineering in 1962. Mike then started graduate school in electrical engineering at Michigan State, but after one semester transferred to the University of Michigan, Ann Arbor, where he earned an MS (1966) and PhD (1968) in astronomy. His doctoral dissertation, under the direction of Professor Fred Haddock, was based on extensive observations of the planets and examined the physical and thermal properties of planetary atmospheres and surfaces. Mike was awarded a Resident Research Associate position at JPL by the National

  8. Evaluation of GPS Coverage for the X-33 Michael-6 Trajectory

    NASA Technical Reports Server (NTRS)

    Lundberg, John B.

    1998-01-01

    The onboard navigational system for the X-33 test flights will be based on the use of measurements collected from the Embedded Global Positioning System (GPS)/INS system. Some of the factors which will affect the quality of the GPS contribution to the navigational solution will be the number of pseudorange measurements collected at any instant in time, the distribution of the GPS satellites within the field of view, and the inherent noise level of the GPS receiver. The distribution of GPS satellites within the field of view of the receiver's antenna will depend on the receiver's position, the time of day, pointing direction of the antenna, and the effective cone angle of the antenna. The number of pseudorange measurements collected will depend upon these factors as well as the time required to lock onto a GPS satellite signal once the GPS satellite comes into the field of view of the antenna and the number of available receiver channels. The objective of this study is to evaluate the GPS coverage resulting from the proposed antenna pointing directions, the proposed antenna cone angles, and the effects due to the time of day for the X-33 Michael-6 trajectory from launch at Edwards AFB, California, to the start of the Terminal Area Energy Management (TAEM) phase on approach to Michael AAF, Utah.

  9. The Discernment Process of the Sisters of Saint Dominic regarding the Continued Sponsorship of Its Secondary Schools

    ERIC Educational Resources Information Center

    Tavis, Patricia

    2010-01-01

    The purpose of this dissertation was to examine the factors that a congregation of women religious, the Sisters of Saint Dominic of Caldwell, New Jersey, must consider in order to continue its sponsored relationship and the extent of this sponsored relationship with its secondary educational ministries for the future. This descriptive and…

  10. 33 CFR 165.760 - Security Zones; Tampa Bay, Port of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake, Old Port Tampa, Big Bend, Weedon..., Old Port Tampa, Big Bend, Weedon Island, and Crystal River, Florida. (a) Location. The following areas, denoted by coordinates fixed using the North American Datum of 1983 (World Geodetic System 1984), are...

  11. 33 CFR 165.760 - Security Zones; Tampa Bay, Port of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake, Old Port Tampa, Big Bend, Weedon..., Old Port Tampa, Big Bend, Weedon Island, and Crystal River, Florida. (a) Location. The following areas, denoted by coordinates fixed using the North American Datum of 1983 (World Geodetic System 1984), are...

  12. 33 CFR 165.760 - Security Zones; Tampa Bay, Port of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake, Old Port Tampa, Big Bend, Weedon..., Old Port Tampa, Big Bend, Weedon Island, and Crystal River, Florida. (a) Location. The following areas, denoted by coordinates fixed using the North American Datum of 1983 (World Geodetic System 1984), are...

  13. 33 CFR 165.760 - Security Zones; Tampa Bay, Port of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake, Old Port Tampa, Big Bend, Weedon..., Old Port Tampa, Big Bend, Weedon Island, and Crystal River, Florida. (a) Location. The following areas, denoted by coordinates fixed using the North American Datum of 1983 (World Geodetic System 1984), are...

  14. 33 CFR 165.760 - Security Zones; Tampa Bay, Port of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake, Old Port Tampa, Big Bend, Weedon..., Old Port Tampa, Big Bend, Weedon Island, and Crystal River, Florida. (a) Location. The following areas, denoted by coordinates fixed using the North American Datum of 1983 (World Geodetic System 1984), are...

  15. Enantioselective Michael Addition of Pyrroles with Nitroalkenes in Aqueous Media Catalyzed by a Water-soluble Catalyst.

    PubMed

    Gui, Yang; Li, Yanan; Sun, Jianan; Zha, Zhenggen; Wang, Zhiyong

    2018-06-11

    A new water-soluble catalytic system were developed and therefor used in an enantioselective Michael addition of pyrroles with nitroalkenes in water to afford the nitroethylpyrrole derivatives with both excellent yields and ee values.

  16. The "Patron Saint" of Comprehensive Education: An Interview with Clyde Chitty. Part One

    ERIC Educational Resources Information Center

    Benn, Melissa; Martin, Jane

    2017-01-01

    FORUM invited Melissa Benn and Jane Martin to interview Clyde Chitty, a brilliant and effective classroom and university teacher, one of the most well-known advocates of comprehensive education, a long-standing member of FORUM's editorial board, and for two decades co-editor of the publication. It was Michael Armstrong who called him 'the patron…

  17. "Raising Standards" or Reducing Aspirations and Opportunities Still Further? Michael Gove and Examination Reforms

    ERIC Educational Resources Information Center

    Allen, Martin

    2013-01-01

    Well before the examinations grade crisis of 2012, Michael Gove had set out clear intentions for reforming public examinations. Though he claimed to be improving examinations and assessment by replicating practices that took place in high-performing countries and thus improving the ability of the UK economy to "compete", this…

  18. Wolff-Michael Roth's passibility: at the limits of the constructivist metaphor: a book review

    NASA Astrophysics Data System (ADS)

    Brendel, Michelle

    2014-12-01

    Wolff-Michael Roth deconstructs the preeminent role conceded to constructivism in Science Education and demonstrates how we learn and know through pain, suffering, love or passion. This review explores his book "Passibility: At the Limits of the Constructivist Metaphor" through the eyes of an outsider to the world of science education.

  19. Michael's Inform Test of Student Ability (M.I.T.O.S.A.). Tester's Manual.

    ERIC Educational Resources Information Center

    Grafius, Thomas M.

    Michael's Informal Test of Student Ability (MITOSA) is a diagnostic evaluative tool for adult students designed to test nine skills abilities in adult students functioning below a tenth grade level. The nine test sections are approximate reading level, understanding of basic math concepts and symbols, general thinking/reasoning ability, eye-hand…

  20. Superelastic and pH-Responsive Degradable Dendrimer Cryogels Prepared by Cryo-aza-Michael Addition Reaction.

    PubMed

    Wang, Juan; Yang, Hu

    2018-05-08

    Dendrimers exhibit super atomistic features by virtue of their well-defined discrete quantized nanoscale structures. Here, we show that hyperbranched amine-terminated polyamidoamine (PAMAM) dendrimer G4.0 reacts with linear polyethylene glycol (PEG) diacrylate (575 g/mol) via the aza-Michael addition reaction at a subzero temperature (-20 °C), namely cryo-aza-Michael addition, to form a macroporous superelastic network, i.e., dendrimer cryogel. Dendrimer cryogels exhibit biologically relevant Young's modulus, high compression elasticity and super resilience at ambient temperature. Furthermore, the dendrimer cryogels exhibit excellent rebound performance and do not show significant stress relaxation under cyclic deformation over a wide temperature range (-80 to 100 °C). The obtained dendrimer cryogels are stable at acidic pH but degrade quickly at physiological pH through self-triggered degradation. Taken together, dendrimer cryogels represent a new class of scaffolds with properties suitable for biomedical applications.

  1. Talbot-Lau x-ray deflectometry phase-retrieval methods for electron density diagnostics in high-energy density experiments.

    PubMed

    Valdivia, Maria Pia; Stutman, Dan; Stoeckl, Christian; Mileham, Chad; Begishev, Ildar A; Bromage, Jake; Regan, Sean P

    2018-01-10

    Talbot-Lau x-ray interferometry uses incoherent x-ray sources to measure refraction index changes in matter. These measurements can provide accurate electron density mapping through phase retrieval. An adaptation of the interferometer has been developed in order to meet the specific requirements of high-energy density experiments. This adaptation is known as a moiré deflectometer, which allows for single-shot capabilities in the form of interferometric fringe patterns. The moiré x-ray deflectometry technique requires a set of object and reference images in order to provide electron density maps, which can be costly in the high-energy density environment. In particular, synthetic reference phase images obtained ex situ through a phase-scan procedure, can provide a feasible solution. To test this procedure, an object phase map was retrieved from a single-shot moiré image obtained from a plasma-produced x-ray source. A reference phase map was then obtained from phase-stepping measurements using a continuous x-ray tube source in a small laboratory setting. The two phase maps were used to retrieve an electron density map. A comparison of the moiré and phase-stepping phase-retrieval methods was performed to evaluate single-exposure plasma electron density mapping for high-energy density and other transient plasma experiments. It was found that a combination of phase-retrieval methods can deliver accurate refraction angle mapping. Once x-ray backlighter quality is optimized, the ex situ method is expected to deliver electron density mapping with improved resolution. The steps necessary for improved diagnostic performance are discussed.

  2. New eco-friendly animal bone meal catalysts for preparation of chalcones and aza-Michael adducts

    PubMed Central

    2012-01-01

    Abstract Two efficient reactions were successfully carried out using Animal Bone Meal (ABM) and potassium fluoride or sodium nitrate doped ABMs as new heterogeneous catalysts under very mild conditions. After preparation and characterization of the catalysts, we first report their use in a simple and convenient synthesis of various chalcones by Claisen–Schmidt condensation and then in an aza-Michael addition involving several synthesized chalcones with aromatic amines. All the reactions were carried out at room temperature in methanol; the chalcone synthesis was also achieved in water environment under microwave irradiation. Doping ABM enhances the rate and yield at each reaction. Catalytic activities are discussed and the ability to re-use the ABM is demonstrated. Results For Claisen–Schmidt the use of ABM alone, yields never exceeded 17%. In each entry, KF/ABM and NaNO3/ABM (79-97%) gave higher yields than using ABM alone under thermic condition. Also the reaction proceeded under microwave irradiation in good yields (72-94% for KF/ABM and 81-97% for NaNO3/ABM) and high purity. For aza-Michael addition the use of ABM doped with KF or NaNO3 increased the catalytic activity remarkably. The very high yields could be noted (84-95% for KF/ABM and 81-94% for NaNO3/ABM). Conclusion The present method is an efficient and selective procedure for the synthesis of chalcones an aza-Michael adducts. The ABM and doped ABMs are a new, inexpensive and attractive solid supports which can contribute to the development of catalytic processes and reduced environmental problems. PMID:22721409

  3. Structure and Tectonics of the Saint Elias Orogen

    NASA Astrophysics Data System (ADS)

    Bruhn, R. L.; Pavlis, T. L.; Plafker, G.; Serpa, L.; Picornell, C.

    2001-12-01

    The Saint Elias orogen of western Canada and southern Alaska is a complex mountain belt formed by transform faulting and subduction between the Pacific and North American plates, and collision of the Yakutat terrane. The orogen is segmented into three regions of different structural style caused by lateral variations in transpression and processes of terrane accretion. Deformation is strain and displacement partitioned throughout the orogen; transcurrent motion is focused along discrete strike-slip faults, and shortening is distributed among reverse faults and folds with sub-horizontal axes. Plunging folds accommodate horizontal shortening and extension in the western part of the orogen. Segment boundaries extend across the Yakutat terrane where they coincide with the courses of huge piedmont glaciers that flow from the topographic backbone of the range onto the coastal plain. The eastern segment is marked by strike-slip faulting along the Fairweather transform fault and by a narrow belt of reverse faulting where the transpression ratio is 0.4:1 shortening to dextral shear. The transpression ratio is 1.7:1 in the central part of the orogen where a broad thin-skinned fold and thrust belt deforms the Yakutat terrane south of the Chugach-Saint Elias (CSE) suture. Dextral shearing is accommodated by strike-slip faulting beneath the Seward and Bagley glaciers in the hanging wall of the CSE suture, and partly by reverse faulting along a structural belt that cuts across the Yakutat terrane along the western edge of the Malaspina Glacier and links to the Pamplona fold and thrust belt offshore. Deformation along this segment boundary is probably also driven by vertical axis bending of the Yakutat microplate during collision. Subduction & accretion in the western segment of the orogen causes re-folding of previously formed structures when they are emplaced into the upper plate of the Alaska-Aleutian mega-thrust. Second phase folds plunge at moderate to steep angles and

  4. The "Patron Saint" of Comprehensive Education: An Interview with Clyde Chitty. Part Two

    ERIC Educational Resources Information Center

    Benn, Melissa; Martin, Jane

    2018-01-01

    This is the second and concluding part of the interview which Melissa Benn and Jane Martin conducted with Clyde Chitty in the summer of 2017. The first part appeared in the previous issue of the journal, "FORUM," 59(3). When Clyde stepped away from regular duties with the FORUM board, Michael Armstrong dubbed him "the patron saint…

  5. STS-109 Crew Interviews: Michael J. Massimino

    NASA Technical Reports Server (NTRS)

    2002-01-01

    STS-109 Mission Specialist Michael J. Massimino is seen during a prelaunch interview. He answers questions about his inspiration to become an astronaut, his career path, and his most memorable experiences. He gives details on the mission's goals and objectives, which focus on the refurbishing of the Hubble Space Telescope, and his role in the mission. He explains the plans for the rendezvous of the Columbia Orbiter with the Hubble Space Telescope. He provides details and timelines for each of the planned Extravehicular Activities (EVAs), which include replacing the solar arrays, changing the Power Control Unit, installing the Advanced Camera for Surveys (ACS), and installing a new Cryocooler for the Near Infrared Camera and Multi-Object Spectrometer (NICMOS). He also describes the break-out plan in place for these spacewalks. The interview ends with Massimino explaining the details of a late addition to the mission's tasks, which is to replace a reaction wheel on the Hubble Space Telescope.

  6. The extraordinary impact of Michael Faraday on chemistry and related subjects.

    PubMed

    Thomas, John Meurig

    2017-08-25

    Biographers of Michael Faraday, as well as many dictionaries of science, often describe him as a physicist, which he certainly was. But he was also an astonishingly effective chemist: in fact, he was the Fullerian Professor of Chemistry (at the Royal Institution, RI) from 1834 until the time of his death in August, 1867. To mark the sesquicentenary of his passing, this editorial, by one of his distant successors as Director and Fullerian Professor at the RI, focuses on Faraday's output and influence as a scientist.

  7. 77 FR 15600 - Special Local Regulation; Emerald Coast Super Boat Grand Prix; Saint Andrew Bay; Panama City, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ...-AA08 Special Local Regulation; Emerald Coast Super Boat Grand Prix; Saint Andrew Bay; Panama City, FL... navigable waters during the Emerald Coast Super Boat Grand Prix high speed boat races. Entry into... Marine Event Permit on January 31, 2011 from Super Boat International, Inc. to conduct a high speed boat...

  8. What makes a Catholic hospital "Catholic" in an age of religious-secular collaboration? The case of the Saint Marys hospital and the Mayo Clinic.

    PubMed

    Swetz, Keith M; Crowley, Mary E; Maines, T Dean

    2013-06-01

    Mayo Clinic is recognized as a worldwide leader in innovative, high-quality health care. However, the Catholic mission and ideals from which this organization was formed are not widely recognized or known. From partnership with the Sisters of St. Francis in 1883, through restructuring of the Sponsorship Agreement in 1986 and current advancements, this Catholic mission remains vital today at Saint Marys Hospital. This manuscript explores the evolution and growth of sponsorship at Mayo Clinic, defined as "a collaboration between the Sisters of St. Francis and Mayo Clinic to preserve and promote key values that the founding Franciscan sisters and Mayo physicians embrace as basic to their mission, and to assure the Catholic identity of Saint Marys Hospital." Historical context will be used to frame the evolution and preservation of Catholic identity at Saint Marys Hospital; and the shift from a "sponsorship-by-governance" to a "sponsorship-by-influence" model will be highlighted. Lastly, using the externally-developed Catholic Identity Matrix (developed by Ascension Health and the University of St. Thomas, Minnesota), specific examples of Catholic identity will be explored in this joint venture of Catholic health care institution and a secular, nonprofit corporation (Mayo Clinic).

  9. Gender Relations and Sexual Harassment in the Workplace: Michael Crichton's "Disclosure" as a Teaching Tool.

    ERIC Educational Resources Information Center

    Comer, Debra R.; Cooper, Elizabeth A.

    1998-01-01

    Describes how to use Michael Crichton's novel "Disclosure" and the film based on it for class discussions of such issues as what constitutes sexual harassment, harassment of men, relationship between sexual harassment and power, organizational responses to harassment, and gender differences in career advancement tactics. (SK)

  10. Double hetero-Michael addition of N-substituted hydroxylamines to quinone monoketals: synthesis of bridged isoxazolidines.

    PubMed

    Yin, Zhiwei; Zhang, Jinzhu; Wu, Jing; Liu, Che; Sioson, Kate; Devany, Matthew; Hu, Chunhua; Zheng, Shengping

    2013-07-19

    A general synthesis of bridged isoxazolidines from a double hetero-Michael addition of N-substituted hydroxylamines to quinone monoketals has been developed. The different addition order of N-benzylhydroxylamine and N-Boc hydroxylamine is also discussed. Moreover, the various functionalities in the isoxazolidine products allow facile derivatization.

  11. David Cozad, Michael Schumacher and/or Brad Peterson (d/b/a Credit Island Recycling), Davenport, Iowa

    EPA Pesticide Factsheets

    The EPA is providing notice of proposed Administrative Penalty Assessment against David Cozad, Michael Schumacher and/or Brad Peterson (d/b/a Credit Island Recycling), for alleged violations of an industrial stormwater permit issued by IDNR for an applianc

  12. [Rochus, patron saint of physicians and hospitals--a teledermatologic quiz].

    PubMed

    Aberer, Werner

    2006-07-01

    The painting "St. Rochus with an angel" by Quinten Massys in the Alte Pinakothek in Munich was utilized for a teledermatological quiz. First, only a detail of the plague bubo on the thigh was sent electronically to all physicians in our department. The answers were correct descriptions, but the interpretations quite heterogeneous. In a second set, the full painting together with the hint- Pinakothek - was given. Now the number of descriptively correct diagnoses was high; one resident knew the name of the featured individual and his diagnosis. This example demonstrates one problem with teledermatology - when viewing a clinical picture, relevant additional information is frequently essential in order to make a correct diagnosis. In addition, this presentation of saint physicians and hospitals, the holy Rochus, better known to those who are under his protection.

  13. Saint-Venant end effects for materials with negative Poisson's ratios

    NASA Technical Reports Server (NTRS)

    Lakes, R. S.

    1992-01-01

    Results are presented from an analysis of Saint-Venant end effects for materials with negative Poisson's ratio. Examples are presented showing that slow decay of end stress occurs in circular cylinders of negative Poisson's ratio, whereas a sandwich panel containing rigid face sheets and a compliant core exhibits no anomalous effects for negative Poisson's ratio (but exhibits slow stress decay for core Poisson's ratios approaching 0.5). In sand panels with stiff but not perfectly rigid face sheets, a negative Poisson's ratio results in end stress decay, which is faster than it would be otherwise. It is suggested that the slow decay previously predicted for sandwich strips in plane deformation as a result of the geometry can be mitigated by the use of a negative Poisson's ratio material for the core.

  14. Dr Michaels® product family (also branded as Soratinex®) versus Methylprednisolone aceponate - a comparative study of the effectiveness for the treatment of plaque psoriasis.

    PubMed

    Hercogovấ, J; Fioranelli, M; Gianfaldoni, S; Chokoeva, A A; Tchernev, G; Wollina, U; Tirant, M; Novotny, F; Roccia, M G; Maximov, G K; França, K; Lotti, T

    2016-01-01

    As one of the most common dermatologic chronic-recurrent disease, variable therapeutic options are available today for management of psoriasis. Although topical high potency corticosteroids, alone or in association with salicylic acid or vitamin D analogues, are still considered the best treatment, they do not seem to possess the capability for a long-term control of the disease or prevent recurrences, as their side effects are major contraindications for continuative use. The aim of this study was to investigate whether Dr. Michaels® product family is comparable to methylprednisolone aceponate (MPA) as a viable alternative treatment option for the treatment and management of stable chronic plaque psoriasis. Thirty adults (13 male, 17 female, mean age 40 years) with mild to severe stable chronic plaque psoriasis, were included in the study. Patients were advised to treat the lesions of the two sides of their body (left and right) with two different unknown modalities for 8 weeks; the pack of Dr. Michaels® products on the left side (consisting of a cleansing gel, an ointment and a skin conditioner) and a placebo pack on the right side, consisting of a cleansing gel, methylprednisolone ointment and a placebo conditioner. Assessment was done using the Psoriasis Activity Severity Index (PASI) scores before treatment and after 2, 4, 6 and 8 weeks. The results achieved with the Dr. Michaels® (Soratinex®) product family for the treatment of chronic plaque psoriasis were better than the results achieved with methylprednisolone aceponate (MPA), even though quicker resolution was achieved with the steroid with 45% of patients achieving resolution within 8-10 days in comparison to 5-6 weeks in the Dr. Michaels® (Soratinex®) group. Before therapy, the mean PASI score of the LHS in Dr. Michaels® (Soratinex®) group was 13.8±4.1 SD and 14.2±4.2 SD in the RHS methylprednisolone aceponate (MPA) group. After 8 weeks of treatment 62% of the Dr. Michaels® (Soratinex

  15. STS-84 Mission Specialist C. Michael Foale in white room

    NASA Technical Reports Server (NTRS)

    1997-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-84 Mission Specialist C. Michael Foale prepares to enter the Space Shuttle Atlantis at Launch Pad 39A with help from white room closeout crew members. The fourth Shuttle mission of 1997 will be the sixth docking of the Space Shuttle with the Russian Space Station Mir. The commander is Charles J. Precourt. The pilot is Eileen Marie Collins. The five mission specialists are C. Michael Foale, Carlos I. Noriega, Edward Tsang Lu, Jean-Francois Clervoy of the European Space Agency and Elena V. Kondakova of the Russian Space Agency. The planned nine-day mission will include the exchange of Foale for U.S. astronaut and Mir 23 crew member Jerry M. Linenger, who has been on Mir since Jan. 15. Linenger transferred to Mir during the last docking mission, STS-81; he will return to Earth on Atlantis. Foale is slated to remain on Mir for about four months until he is replaced in September by STS-86 Mission Specialist Wendy B. Lawrence. During the five days Atlantis is scheduled to be docked with the Mir, the STS-84 crew and the Mir 23 crew, including two Russian cosmonauts, Commander Vasily Tsibliev and Flight Engineer Alexander Lazutkin, will participate in joint experiments. The STS-84 mission also will involve the transfer of more than 7,300 pounds of water, logistics and science equipment to and from the Mir. Atlantis is carrying a nearly 300-pound oxygen generator to replace one of two Mir units which have experienced malfunctions. The oxygen it generates is used for breathing by the Mir crew.

  16. [An image of Saint Ottilia with reading stones].

    PubMed

    Daxecker, F; Broucek, A

    1995-01-01

    Reading stones to facilitate reading in cases of presbyopia are mentioned in the literature, for example in the works of the Middle High German poet Albrecht and of Konrad of Würzburg. Most representations of the abbess, Saint Ottilia, show her holding a book with a pair of eyes in her hands. A gothic altarpiece (1485-1490), kept in the museum of the Premonstratensian Canons of Wilten in Innsbruck, Tyrol, shows a triune representation of St. Anne, the mother of the Virgin, with Mary and Jesus and St. Ursula with her companions. St. Ottilia is depicted on the edge of the painting. Two lenses, one on either side of the open book in her hand, magnify the letters underneath. As the two lenses are not held together by bows or similar devices, they are probably a rare representation of reading stones. The alter showing scenes of the life of St. Mary and St. Ursula was done by Ludwig Konraiter. A panel on the same alter, depicting the death of the Virgin, shows an apostle with rivet spectacles.

  17. Education, Philosophy and Politics: The Selected Works of Michael A. Peters. World Library of Educationalists

    ERIC Educational Resources Information Center

    Peters, Michael A.

    2012-01-01

    In the World Library of Educationalists series, international experts themselves compile career-long collections of what they judge to be their finest pieces--extracts from books, key articles, salient research findings, major theoretical and/practical contributions--so the world can read them in a single manageable volume. Michael A. Peters has…

  18. Targeting Rapamycin to Podocytes Using a Vascular Cell Adhesion Molecule-1 (VCAM-1)-Harnessed SAINT-Based Lipid Carrier System

    PubMed Central

    Visweswaran, Ganesh Ram R.; Gholizadeh, Shima; Ruiters, Marcel H. J.; Molema, Grietje; Kok, Robbert J.; Kamps, Jan. A. A. M.

    2015-01-01

    Together with mesangial cells, glomerular endothelial cells and the basement membrane, podocytes constitute the glomerular filtration barrier (GFB) of the kidney. Podocytes play a pivotal role in the progression of various kidney-related diseases such as glomerular sclerosis and glomerulonephritis that finally lead to chronic end-stage renal disease. During podocytopathies, the slit-diaphragm connecting the adjacent podocytes are detached leading to severe loss of proteins in the urine. The pathophysiology of podocytopathies makes podocytes a potential and challenging target for nanomedicine development, though there is a lack of known molecular targets for cell selective drug delivery. To identify VCAM-1 as a cell-surface receptor that is suitable for binding and internalization of nanomedicine carrier systems by podocytes, we investigated its expression in the immortalized podocyte cell lines AB8/13 and MPC-5, and in primary podocytes. Gene and protein expression analyses revealed that VCAM-1 expression is increased by podocytes upon TNFα-activation for up to 24 h. This was paralleled by anti-VCAM-1 antibody binding to the TNFα-activated cells, which can be employed as a ligand to facilitate the uptake of nanocarriers under inflammatory conditions. Hence, we next explored the possibilities of using VCAM-1 as a cell-surface receptor to deliver the potent immunosuppressant rapamycin to TNFα-activated podocytes using the lipid-based nanocarrier system Saint-O-Somes. Anti-VCAM-1-rapamycin-SAINT-O-Somes more effectively inhibited the cell migration of AB8/13 cells than free rapamycin and non-targeted rapamycin-SAINT-O-Somes indicating the potential of VCAM-1 targeted drug delivery to podocytes. PMID:26407295

  19. Analysis of the effects of human activities on the hydromorphological evolution channel of the Saint-Maurice River downstream from La Gabelle dam (Quebec, Canada)

    NASA Astrophysics Data System (ADS)

    Vadnais, Marie-Ève; Assani, Ali A.; Landry, Raphaëlle; Leroux, Denis; Gratton, Denis

    2012-11-01

    During the first half of the twentieth century, many hydroelectric facilities were built in the Saint-Maurice River watershed, followed by other human activities in the second half of the century (pleasure boating, boom dismantling, urbanization, etc.). The goal of the study is to constrain the effects of these various types of human activities, particularly those of the many dams in the watershed, on the hydromorphological evolution of the Saint-Maurice River downstream from the La Gabelle (dam) power plant (43,000 km2). Comparison of specific discharge in this river with streamflow measured in a natural river setting reveals a significant decrease in seasonal maximum flows, aside from winter, when daily maximum flows increased significantly. Also, unlike natural rivers, the long-term trend in spring flows is not characterized by a significant change in mean downstream from the La Gabelle plant. These hydrological changes are linked to the inversion-type management mode of the reservoirs built downstream from the plant. As for the morphological evolution, the longitudinal variability of bankfull width downstream from the plant shows two significant shifts in mean: the first, which was quasi-abrupt, took place downstream of the des Forges rapid; and the second, which was gradual, occurred upstream from the confluence of the Saint-Maurice River with the St. Lawrence River, above the point where the Saint-Maurice splits into two branches. Comparison of aerial photographs taken at various times (1948, 1964, 1975, 1996, and 2008) reveals no significant change in the mean of bankfull width over time. However, a significant increase in the surface area of islets located at the confluence was observed, which is caused by sediment accumulation. These sediments were likely derived from local bank erosion resulting from anthropogenic changes.

  20. A Proposed Community Network For Monitoring Volcanic Emissions In Saint Lucia, Lesser Antilles

    NASA Astrophysics Data System (ADS)

    Joseph, E. P.; Beckles, D. M.; Robertson, R. E.; Latchman, J. L.; Edwards, S.

    2013-12-01

    Systematic geochemical monitoring of volcanic systems in the English-speaking islands of the Lesser Antilles was initiated by the UWI Seismic Research Centre (SRC) in 2000, as part of its volcanic surveillance programme for the English-speaking islands of the Lesser Antilles. This programme provided the first time-series observations used for the purpose of volcano monitoring in Dominica and Saint Lucia, permitted the characterization of the geothermal fluids associated with them, and established baseline studies for understanding of the hydrothermal systems during periods of quiescence (Joseph et al., 2011; Joseph et al., 2013). As part of efforts to improve and expand the capacity of SRC to provide volcanic surveillance through its geothermal monitoring programme, it is necessary to develop economically sustainable options for the monitoring of volcanic emissions/pollutants. Towards this effort we intend to work in collaboration with local authorities in Saint Lucia, to develop a monitoring network for quantifying the background exposure levels of ambient concentrations of volcanic pollutants, SO2 in air and As in waters (as health significant marker elements in the geothermal emissions) that would serve as a model for the emissions monitoring network for other volcanic islands. This programme would facilitate the building of local capacity and training to monitor the hazardous exposure, through the application and transfer of a regionally available low-cost and low-technology SO2 measurement/detection system in Saint Lucia. Existing monitoring technologies to inform evidence based health practices are too costly for small island Caribbean states, and no government policies or health services measures currently exist to address/mitigate these influences. Gases, aerosols and toxic elements from eruptive and non-eruptive volcanic activity are known to adversely affect human health and the environment (Baxter, 2000; Zhang et al., 2008). Investigations into the

  1. Michael Tuomey's 1848 geological survey of South Carolina

    USGS Publications Warehouse

    Nystrom, P.G.

    1999-01-01

    One hundred and fifty years ago, Michael Tuomey completed his 'Report on the Geology of South Carolina,' the result of four years of arduous labor. The report is the first detailed and comprehensive geological description of the entire state, and it includes a geological map that shows the distribution of Coastal Plain and Piedmont-Blue Ridge units. In the sesquicentennial of Tuomey's survey, it is fitting that we recognize his important early contribution to the geology of South Carolina and the southeast. Tuomey's report is a 293-page volume with a 48-page appendix and an index. Although he gave a complete depiction of Coastal Plain geology and delineated Cretaceous, Lower Eocene, Eocene, Miocene, Post-Pliocene, and alluvial units on his map, the emphasis herein is on his mapping of the Piedmont and Blue Ridge. The metamorphic units he delineated are clay slate, mica slate, talcose slate, hornblende slate, gneiss, and lime rock. Gneiss is the most extensive unit on the map. His map shows many elements of the geologic framework we recognize today. The distribution of his clay slate unit corresponds closely with the Carolina slate and Bel Air belts as we know them now. The gneiss between the two clay slate areas matches the Kiokee belt. Areas of mica slate approximate the northern part of the Kings Mountain belt and the Chauga belt. He also recognized that his talcose slate unit was associated with gold deposits. Granitic and basaltic intrusive rocks are also delineated on the map. It shows the Newberry, Columbia, and Liberty Hill granites we recognize today. Basaltic intrusives outlined include the Bush River of western Newberry County, Dutchmans Creek, Big Wateree Creek, and Ogden gabbros. He described the regional extent of diabase dikes as occuring from Virginia to Alabama, noted their preferred direction and diagrammed their near-vertical orientation. He also referred to the distinctive soil and topography that develops on the large gabbros. Michael Tuomey

  2. Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous transformations.

    PubMed

    Aceña, José Luis; Sorochinsky, Alexander E; Soloshonok, Vadim

    2014-09-01

    The major goal of this review is a critical discussion of the literature data on asymmetric synthesis of α-amino acids via Michael addition reactions involving Ni(II)-complexes of amino acids. The material covered is divided into two conceptually different groups dealing with applications of: (a) Ni(II)-complexes of glycine as C-nucleophiles and (b) Ni(II)-complexes of dehydroalanine as Michael acceptors. The first group is significantly larger and consequently subdivided into four chapters based on the source of stereocontrolling element. Thus, a chiral auxiliary can be used as a part of nucleophilic glycine Ni(II) complex, Michael acceptor or both, leading to the conditions of matching vs. mismatching stereochemical preferences. The particular focus of the review is made on the practical aspects of the methodology under discussion and mechanistic considerations.

  3. Mercury bioaccumulation in aquatic biota along a salinity gradient in the Saint John River estuary.

    PubMed

    Reinhart, Bethany L; Kidd, Karen A; Curry, R Allen; O'Driscoll, Nelson J; Pavey, Scott A

    2018-06-01

    Although estuaries are critical habitats for many aquatic species, the spatial trends of toxic methylmercury (MeHg) in biota from fresh to marine waters are poorly understood. Our objective was to determine if MeHg concentrations in biota changed along a salinity gradient in an estuary. Fourspine Stickleback (Apeltes quadracus), invertebrates (snails, amphipods, and chironomids), sediments, and water were collected from ten sites along the Saint John River estuary, New Brunswick, Canada in 2015 and 2016, with salinities ranging from 0.06 to 6.96. Total mercury (proxy for MeHg) was measured in whole fish and MeHg was measured in a subset of fish, pooled invertebrates, sediments, and water. Stable sulfur (δ 34 S), carbon (δ 13 C), and nitrogen (δ 15 N) isotope values were measured to assess energy sources (S, C) and relative trophic level (N). There were increases in biotic δ 13 C and δ 34 S from fresh to more saline sites and these measures were correlated with salinity. Though aqueous MeHg was higher at the freshwater than more saline sites, only chironomid MeHg increased significantly with salinity. In the Saint John River estuary, there was little evidence that MeHg and its associated risks increased along a salinity gradient. Copyright © 2018. Published by Elsevier B.V.

  4. STS-107 Crew Interviews: Michael Anderson, Mission Specialist

    NASA Technical Reports Server (NTRS)

    2002-01-01

    STS-107 Mission Specialist 3 and Payload Commander Michael Anderson is seen during this preflight interview, where he gives a quick overview of the mission before answering questions about his inspiration to become an astronaut and his career path. He outlines his role in the mission in general, and specifically in conducting onboard science experiments. He discusses the following instruments and sets of experiments in detail: CM2 (Combustion Module 2), FREESTAR (Fast Reaction Enabling Science Technology and Research, MEIDEX (Mediterranean Israeli Dust Experiment) and MGM (Mechanics of Granular Materials). Anderson also mentions on-board activities and responsibilities during launch and reentry, mission training, and microgravity research. In addition, he touches on the dual work-shift nature of the mission, the use of crew members as research subjects including pre and postflight monitoring activities, the emphasis on crew safety during training and the value of international cooperation.

  5. Shaded Relief Image of Saint Pierre and Miquelon

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This image shows two islands, Miquelon and Saint Pierre, located south of Newfoundland, Canada. These islands, along with five smaller islands, are a self-governing territory of France. A thin barrier beach divides Miquelon, with Grande Miquelon to the north and Petite Miquelonto the south. Saint Pierre Island is located to the lower right. With the islandsi location in the north Atlantic Ocean and their deep water ports, fishing is the major part of the economy. The maximum elevation of the island is 240 meters (787 feet). The land mass of the islands is about 242 square kilometers, or 1.5 times the size of Washington DC.

    This shaded relief image was generated using topographic data from the Shuttle Radar Topography Mission. A computer-generated artificial light source illuminates the elevation data to produce a pattern of light and shadows. Slopes facing the light appear bright, while those facing away are shaded. On flatter surfaces, the pattern of light and shadows can reveal subtle features in the terrain. Shaded relief maps are commonly used in applications such as geologic mapping and land use planning.

    This image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on February 11, 2000. SRTM uses the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. The mission is designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between the National Aeronautics and Space Administration (NASA), the National Imagery and Mapping Agency (NIMA) of the U.S. Department of Defense (DoD), and the German and Italian space agencies. It is managed by NASAis Jet Propulsion

  6. Theoretical study on the reaction mechanisms of Michael chirality addition between propionaldehyde and nitroalkene catalyzed by an enantioselective catalyst.

    PubMed

    Zhou, Xinming; Li, Ling; Sun, Xuejun; Wang, Yajun; Du, Dongmei; Fu, Hui

    2018-06-01

    The asymmetric Michael addition between propionaldehyde and nitroalkene catalyzed by 8-(ethoxycarbonyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylic acid has obtained relatively high yields and excellent enantioselectivities at room temperature. In this study, the molecular structures and optical activity of the most stable conformation I are optimized at B3LYP/6-311++ G(d,p) level. We find that levorotatory conformation I catalyzing the same Michael addition can produce laevo-product A and dextrorotatory conformation I' can obtain the dextral-product A'. These results have guiding significance for further studying on the new chemzymes and the mechanism of the obtained different chiral products. © 2018 Wiley Periodicals, Inc.

  7. “State of the Estuary” - Developing a long term monitoring, assessment and reporting framework for the lower Saint Louis River

    EPA Science Inventory

    As the lower Saint Louis River moves closer and closer to delisting as an Area of Concern, it is incumbent that we measure, assess and report on our success. Going forward, It’s equally important that we continue monitoring to protect and sustain the healthy ecosystems we&...

  8. Chiral N,N'-Dioxide-Organocatalyzed Regio-, Diastereo- and Enantioselective Michael Addition-Alkylation Reaction.

    PubMed

    Feng, Juhua; Yuan, Xiao; Luo, Weiwei; Lin, Lili; Liu, Xiaohua; Feng, Xiaoming

    2016-10-24

    A highly regio-, diastereo- and enantioselective Michael addition-alkylation reaction between α-substituted cyano ketones and (Z)-bromonitrostyrenes has been realized by using a chiral N,N'-dioxide as organocatalyst. A variety of substrates performed well in this reaction, and the corresponding multifunctionalized chiral 2,3-dihydrofurans were obtained in up to 95 % yield with 95:5 dr and 93 % ee. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Recollections of Jack Michael and the Application of Skinner's Analysis of Verbal Behavior

    ERIC Educational Resources Information Center

    Sundberg, Mark L.

    2017-01-01

    Jack Michael offered a course on verbal behavior almost every year throughout his teaching career. Jack was also interested in the application of Skinner's work and in 1976 began to offer a graduate course at Western Michigan University titled Verbal Behavior Applications. Jack and his students pursued the application of Skinner's work on verbal…

  10. A Survey of Basic Educational Opportunities Available to Members of the Church of Jesus Christ of Latter-Day Saints.

    ERIC Educational Resources Information Center

    Cameron, J. Elliot

    To examine the historical background of educational programs of the Church of Jesus Christ of Latter-Day Saints, the Church population, and educational opportunities available to Church members, a questionnaire was sent to presidents of Church missions outside the United States. It was found that Church membership has increased rapidly and could…

  11. St. Michael's Improvement Program - A Collaborative Approach to Sustainable Cost Savings.

    PubMed

    Trafford, Anne; Jane, Danielle

    2017-01-01

    In response to a challenging financial environment and increasing patient demand, St. Michael's Hospital needed to find long-term sustainable solutions to continue to provide high-quality patient care and invest in key priorities. By conducting Operational Reviews in focused areas, the hospital achieved $7.4 million of in-year savings in the first year, found standardizations, process efficiencies and direct cost savings that positioned itself for success in future funding models. Initiatives were grounded in evidence and relied heavily on the effective execution by the leadership, front-line staff and physicians. As organizations face similar challenges, this journey can provide key learnings.

  12. Invited Commentary: Continuing to Loosen the Constraints on Epidemiology in an Age of Change-A Comment on McMichael's "Prisoners of the Proximate".

    PubMed

    Galea, Sandro

    2017-06-01

    Published in 1999, McMichael's "Prisoners of the Proximate: Loosening the Constraints on Epidemiology in an Age of Change" (Am J Epidemiol. 1999;149(10):887-897) outlined an exciting vision for epidemiology as the field that that can help us better understand the drivers of population health so that we may intervene, paving the way for healthier populations. McMichael's paper remains today what it was when it was first published: clear, thoughtful, provocative, and usefully prescriptive in its call to action. McMichael identified 4 constraints facing epidemiology. The field has risen to this challenge and addressed some of these constraints. I discuss how successful (or not) we have been in addressing each of these 4 challenges. © The Author 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  13. Evolution of high-rise construction in Leningrad - Saint Petersburg in the middle of the 20th - Early 21st centuries: projects and Implementation

    NASA Astrophysics Data System (ADS)

    Vaytens, Andrey; Rusanov, Gennadiy; Skryabin, Pavel

    2018-03-01

    One of the most important issues in national urban planning is arrangement of high-rise buildings in the largest cities of Russia. This issue becomes especially acute in such cities as Saint Petersburg, which has unique architectural and urban-planning heritage preserved to a great extent. In this regard, it seems important to trace the evolution of high-rise construction development and arrangement in Leningrad - Saint Petersburg in the middle of the 20th — early 21st centuries. The goal of the article is to consider high-rise construction development regarding both public and residential buildings in comparison of project ideas and results of their implementation in the 1940s-2000s. Prerequisites and issues of high-rise construction of that period are considered. Particular attention is paid to changes in the official urban-planning policy, regulatory framework and attitude of city authorities to high-rise construction. The study was carried out with the consideration of the following historic periods differing in their urban-planning policy: the late 1940s-1950s; 1960s; 1970-1980s; 1990s; 2000s-2010s. Economical prerequisites of high-rise construction and their influence on the modern urban-planning policy during the post-Soviet period are considered. In conclusion, an attempt is made to determine tendencies of high-rise construction development in Saint Petersburg.

  14. STS-107 Payload Commander Michael Anderson during TCDT M113 training activities

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- -- STS-107 Payload Commander Michael Anderson takes a break during training on the operation of an M113 armored personnel carrier during Terminal Countdown Demonstration Test activities, a standard part of launch preparations. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. Launch is planned for Jan. 16, 2003, between 10 a.m. and 2 p.m. EST aboard Space Shuttle Columbia.

  15. Saint Lawrence Seaway Navigation-Aid System Study : Volume II - Appendix B - User's Manual and Documentation of Seaway Capacity and Capacity Analysis Programs

    DOT National Transportation Integrated Search

    1978-09-01

    The requirements for a navigation guidance system which will effect an increase in the ship processing capacity of the Saint Lawrence Seaway (Lake Ontario to Montreal, Quebec) are developed. The requirements include a specification of system position...

  16. Saint Lawrence Seaway Navigation-Aid System Study : Volume III - Appendix C - User's Manual and Documentation of the Ship Maneuvering Requirements Computer Program

    DOT National Transportation Integrated Search

    1978-09-01

    The requirements for a navigation guidance system which will effect an increase in the ship processing capacity of the Saint Lawrence Seaway (Lake Ontario to Montreal, Quebec) are developed. The requirements include a specification of system position...

  17. Expedition 8 Crew Interviews: C. Michael Foale - CDR

    NASA Technical Reports Server (NTRS)

    2003-01-01

    C. Michael Foale, Commander of the Expedition 8 crew to the International Space Station (ISS), answers interview questions in this video. The questions cover: 1) The goals of the Expedition; 2) How his Mir experience prepared him for long-duration spaceflight; 3) The reaction the Columbia accident where he was training in Star City, Russia; 4) Why the rewards of spaceflight are worth the risks; 5) Why he wanted to become an astronaut; 6) His career path; 7) His influences; 8) His path of study; 9) His responsibilities on a mission; 10) What a Soyuz capsule is like; 11) What the oncoming and offgoing ISS crews will do together; 12) How the ISS science mission will be advanced during his stay; 13) Training and plans for extravehicular activity (EVA); 14) Return to Flight of Shuttle; 15) What is needed to make his mission a success; 16) The most valuable contribution of the ISS.

  18. STS-113 Mission Specialist Michael Lopez-Alegria looks over the P1 Truss

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-113 Mission Specialist Michael Lopez-Alegria looks over the P1 Integrated Truss Structure, the primary payload for the mission. The P1 truss will be attached to the central truss segment, S0 Truss, during spacewalks. The payload also includes the Crew and Equipment Translation Aid (CETA) Cart B that can be used by spacewalkers to move along the truss with equipment. STS-113 is scheduled to launch Oct. 6, 2002.

  19. A facile and efficient method of enzyme immobilization on silica particles via Michael acceptor film coatings: immobilized catalase in a plug flow reactor.

    PubMed

    Bayramoglu, Gulay; Arica, M Yakup; Genc, Aysenur; Ozalp, V Cengiz; Ince, Ahmet; Bicak, Niyazi

    2016-06-01

    A novel method was developed for facile immobilization of enzymes on silica surfaces. Herein, we describe a single-step strategy for generating of reactive double bonds capable of Michael addition on the surfaces of silica particles. This method was based on reactive thin film generation on the surfaces by heating of impregnated self-curable polymer, alpha-morpholine substituted poly(vinyl methyl ketone) p(VMK). The generated double bonds were demonstrated to be an efficient way for rapid incorporation of enzymes via Michael addition. Catalase was used as model enzyme in order to test the effect of immobilization methodology by the reactive film surface through Michael addition reaction. Finally, a plug flow type immobilized enzyme reactor was employed to estimate decomposition rate of hydrogen peroxide. The highly stable enzyme reactor could operate continuously for 120 h at 30 °C with only a loss of about 36 % of its initial activity.

  20. 50 CFR Figure 17 to Part 679 - Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA)

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA) 17 Figure 17 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES OF THE EXCLUSIVE...

  1. 50 CFR Figure 17 to Part 679 - Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA)

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA) 17 Figure 17 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES OF THE EXCLUSIVE...

  2. 50 CFR Figure 17 to Part 679 - Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA)

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA) 17 Figure 17 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES OF THE EXCLUSIVE...

  3. 50 CFR Figure 17 to Part 679 - Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA)

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 13 2013-10-01 2013-10-01 false Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA) 17 Figure 17 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES OF THE EXCLUSIVE...

  4. HIGHLY DISATEREOSELECTIVE MICHAEL ADDITION OF FLAVANONE TO ITS CHALCONE PRECURSOR UNDER SOLVENT-FREE CONDITIONS USING MICROWAVES [POSTER

    EPA Science Inventory

    Substituted 2'-hydroxychalcones were found to give an equilibrium mixture of the starting chalcone and the corresponding flavanone inf 4.6-1:3 ratio in the presence of DBU gave two hitherto unknown diasteromeric dimers in a highly diastereoselective Michael addition of the carban...

  5. Mount Saint Helens, Washington, USA, SRTM Perspective: Shaded Relief and Colored Height

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Mount Saint Helens is a prime example of how Earth's topographic form can greatly change even within our lifetimes. The mountain is one of several prominent volcanoes of the Cascade Range that stretches from British Columbia, Canada, southward through Washington, Oregon, and into northern California. Mount Adams (left background) and Mount Hood (right background) are also seen in this view, which was created entirely from elevation data produced by the Shuttle Radar Topography Mission.

    Prior to 1980, Mount Saint Helens had a shape roughly similar to other Cascade peaks, a tall, bold, irregular conic form that rose to 2950 meters (9677 feet). However, the explosive eruption of May 18, 1980, caused the upper 400 meters (1300 feet) of the mountain to collapse, slide, and spread northward, covering much of the adjacent terrain (lower left), leaving a crater atop the greatly shortened mountain. Subsequent eruptions built a volcanic dome within the crater, and the high rainfall of this area lead to substantial erosion of the poorly consolidated landslide material.

    Eruptions at Mount Saint Helens subsided in 1986, but renewed volcanic activity here and at other Cascade volcanoes is inevitable. Predicting such eruptions still presents challenges, but migration of magma within these volcanoes often produces distinctive seismic activity and minor but measurable topographic changes that can give warning of a potential eruption.

    Three visualization methods were combined to produce this image: shading of topographic slopes, color coding of topographic height, and then projection into a perspective view. The shade image was derived by computing topographic slope in the northeast-southwest (left to right) direction, so that northeast slopes appear bright and southwest slopes appear dark. Color coding is directly related to topographic height, with green at the lower elevations, rising through yellow and tan, to white at the highest elevations. The perspective

  6. Nutrient Status and Criteria Development for the Saint John River, Canada, Using a Weight of Evidence Approach

    NASA Astrophysics Data System (ADS)

    Culp, J. M.; Luiker, E. A.; Noel, L.; Curry, A. R.; Hryn, D.; Heard, K.

    2005-05-01

    The Saint John River is the largest in Maine/New Brunswick (673 km in length, draining 55,000 km2) with a history of natural resource use and nutrient effluent release to the watershed since the late 17th century. Our objective was to obtain a basic understanding of the contemporary nutrient conditions of the non-tidal portion of the river in relation to historical conditions, and to consider how the contemporary river is affected by point and non-point source nutrient loadings. The study included review of historical provincial and federal water quality databases dating back to the 1960s. Current water quality monitoring programs have focused on nitrogen (nitrite, nitrate, ammonia, TKN), phosphorus (total, dissolved, and soluble reactive phosphorus), DIC/DOC, and biomass of periphyton and phytoplankton. To determine nutrient limitation, nutrient diffusing substrate studies were conducted in river reaches of known nutrient enrichment. Oxygen stable isotopes were also used to provide information on the photosynthesis to respiration ratio. A weight of evidence approach combining the results of these studies was used to determine trophic status of river reaches and to highlight areas of eutrophication. From this information nutrient criteria for the Saint John River will be proposed.

  7. Jack Michael's Musings on the 60th Anniversary of Skinner's "Verbal Behavior"

    ERIC Educational Resources Information Center

    Esch, Barbara E.; Esch, John W.; Palmer, David C.

    2017-01-01

    When the B. F. Skinner Foundation reprinted Skinner's "Verbal Behavior" in 1992, Jack Michael wrote one of its two forewords, a detailed outline of the book's purpose and scope. On the 60th anniversary of the first publication (1957) of "Verbal Behavior", Jack reflects on the book's impact and its importance to the…

  8. STS-113 Mission Specialist Michael Lopez-Alegria suits up before launch

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-113 Mission Specialist Michael Lopez-Alegria suits up before launch. This will be his third Shuttle flight. The primary mission is bringing the Expedition 6 crew to the Station and returning the Expedition 5 crew to Earth. The major objective of the mission is delivery of the Port 1 (P1) Integrated Truss Assembly, which will be attached to the port side of the S0 truss. Three spacewalks are planned to install and activate the truss and its associated equipment. Launch of Space Shuttle Endeavour on mission STS-113 is scheduled for Nov. 11 at 12:58 a.m. EST.

  9. STS-113 Mission Specialist Michael Lopez-Alegria suits up for launch

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. - STS-113 Mission Specialist Michael Lopez-Alegria suits up for launch. He will be making his third Shuttle flight. The primary mission for the crew is bringing the Expedition 6 crew to the Station and returning the Expedition 5 crew to Earth. The major objective of the mission is delivery of the Port 1 (P1) Integrated Truss Assembly, which will be attached to the port side of the S0 truss. Three spacewalks are planned to install and activate the truss and its associated equipment. Launch of Space Shuttle Endeavour on mission STS-113 is scheduled for 8:15 p.m. EST.

  10. Hexamethoxylated Monocarbonyl Analogues of Curcumin Cause G2/M Cell Cycle Arrest in NCI-H460 Cells via Michael Acceptor-Dependent Redox Intervention.

    PubMed

    Li, Yan; Zhang, Li-Ping; Dai, Fang; Yan, Wen-Jing; Wang, Hai-Bo; Tu, Zhi-Shan; Zhou, Bo

    2015-09-09

    Curcumin, derived from the dietary spice turmeric, holds promise for cancer prevention. This prompts much interest in investigating the action mechanisms of curcumin and its analogues. Two symmetrical hexamethoxy-diarylpentadienones (1 and 2) as cucumin analogues were reported to possess significantly enhanced cytotoxicity compared with the parent molecule. However, the detailed mechanisms remain unclear. In this study, compounds 1 and 2 were identified as the G2/M cell cycle arrest agents to mediate the cytotoxicity toward NCI-H460 cells via Michael acceptor-dependent redox intervention. Compared with curcumin, they could more easily induce a burst of reactive oxygen species (ROS) and collapse of the redox buffering system. One possible reason is that they could more effectively target intracellular TrxR to convert this antioxidant enzyme into a ROS promoter. Additionally, they caused up-regulation of p53 and p21 and down-regulation of redox-sensitive Cdc25C along with cyclin B1/Cdk1 in a Michael acceptor- and ROS-dependent fashion. Interestingly, in comparison with compound 2, compound 1 displayed a relatively weak ability to generate ROS but increased cell cycle arrest activity and cytotoxicity probably due to its Michael acceptor-dependent microtubule-destabilizing effect and greater GST-inhibitory activity, as well as its enhanced cellular uptake. This work provides useful information for understanding Michael acceptor-dependent and redox-mediated cytotoxic mechanisms of curcumin and its active analogues.

  11. Catalyst-free and solvent-free Michael addition of 1,3-dicarbonyl compounds to nitroalkenes by a grinding method

    PubMed Central

    Xie, Zong-Bo; Wu, Ming-Yu; He, Ting; Le, Zhang-Gao

    2012-01-01

    Summary An environmentally benign, fast and convenient protocol has been developed for the Michael addition of 1,3-dicarbonyl compounds to β-nitroalkenes in good to excellent yields by a grinding method under catalyst- and solvent-free conditions. PMID:22563352

  12. A Collaborative Approach to Monitoring Ambient Volcanogenic Pollution at Sulphur Springs, Saint Lucia.

    NASA Astrophysics Data System (ADS)

    Joseph, E. P.; Beckles, D. M.; Cox, L.; Jackson, V. B.; Alexander, D.

    2015-12-01

    The role of volcano tourism is recognized as an important contributor to the economy of volcanic islands in the Lesser Antilles. However, if it is to be promoted as a sustainable sector of the tourism industry, visitors, tour operators, and vendors must be made aware of the potential health hazards facing them in volcanic environments. Volcanogenic air pollutants are of primary concern in this setting. In general, no warning signs, guidelines for recreational use, or emissions monitoring currently exists to provide warning to the public to decrease their vulnerability to the potential risks, or to minimize the liability of the agencies managing these areas. Sulphur Springs Park in Saint Lucia is a popular international destination, and concerns about the volcanic emissions and its possible health effect have been raised by visitors, staff, and management of the Park. As part of the responsibility of the UWI, Seismic Research Centre (SRC) to provide volcanic surveillance through its geothermal monitoring programme, a network was established for quantifying the ambient SO2 concentrations at Sulphur Springs in order to assess the potential risk of unsafe exposure. This effort required collaboration with the National Emergency Management Organization (NEMO) of Saint Lucia, as well as the staff and management of the Soufrière Regional Development Foundation (SRDF). Local personnel were trained in the active field sampling and analytical techniques required for the assessment of ambient SO2 concentrations over the monitoring period, thereby contributing to an active community-based effort. This type of approach was also thought to be an effective option for scientists to engage communities as partners in disaster risk reduction. Lessons learnt from this experience are presented for the benefit of other citizen monitoring projects, including its use as a tool for promoting volcanic hazard education, and enhancing communication and understanding between geoscientists and

  13. Gold (III) Chloride-Catalyzed 6-endo-trig Oxa-Michael Addition Reactions for Diastereoselective Synthesis of Fused Tetrahydropyranones

    PubMed Central

    Ciesielski, Jennifer; Lebœuf, David; Stern, Harry A.

    2013-01-01

    Alkynones were treated with boron trifluoride diethyl etherate to generate β-iodoallenolates, which underwent intramolecular aldol reactions to produce cycloalkenyl alcohols. Diastereoselective oxa-Michael ring closure could then be induced by treatment with a catalytic amount of gold(III) chloride, affording highly functionalized tetrahydropyran-containing ring systems. PMID:24032002

  14. Levels of insecticide resistance to deltamethrin, malathion, and temephos, and associated mechanisms in Aedes aegypti mosquitoes from the Guadeloupe and Saint Martin islands (French West Indies).

    PubMed

    Goindin, Daniella; Delannay, Christelle; Gelasse, Andric; Ramdini, Cédric; Gaude, Thierry; Faucon, Frédéric; David, Jean-Philippe; Gustave, Joël; Vega-Rua, Anubis; Fouque, Florence

    2017-02-10

    In the Guadeloupe and Saint Martin islands, Aedes aegypti mosquitoes are the only recognized vectors of dengue, chikungunya, and Zika viruses. For around 40 years, malathion was used as a mosquito adulticide and temephos as a larvicide. Since the European Union banned the use of these two insecticide molecules in the first decade of the 21st century, deltamethrin and Bacillus thuringiensis var. israelensis are the remaining adulticide and larvicide, respectively, used in Guadeloupe. In order to improve the management of vector control activities in Guadeloupe and Saint Martin, we investigated Ae. aegypti resistance to and mechanisms associated with deltamethrin, malathion, and temephos. Ae. aegypti mosquitoes were collected from six different localities of Guadeloupe and Saint Martin. Larvae were used for malathion and temephos bioassays, and adult mosquitoes for deltamethrin bioassays, following World Health Organization recommendations. Knockdown resistance (Kdr) genotyping for V1016I and F1534C mutations, and expression levels of eight enzymes involved in detoxification mechanisms were examined in comparison with the susceptible reference Bora Bora strain. Resistance ratios (RR 50 ) calculated for Ae. aegypti larvae showed high resistance levels to temephos (from 8.9 to 33.1-fold) and low resistance levels to malathion (from 1.7 to 4.4-fold). Adult females displayed moderate resistance levels to deltamethrin regarding the time necessary to affect 50% of individuals, varying from 8.0 to 28.1-fold. Molecular investigations on adult mosquitoes showed high resistant allele frequencies for V1016I and F1534C (from 85 to 96% and from 90 to 98%, respectively), as well as an overexpression of the glutathione S-transferase gene, GSTe2, the carboxylesterase CCEae3a, and the cytochrome genes 014614, CYP6BB2, CYP6M11, and CYP9J23. Ae. aegypti populations from Guadeloupe and Saint Martin exhibit multiple resistance to organophosphates (temephos and malathion), and

  15. Effect of available space and previous contact in the social integration of Saint Croix and Suffolk ewes.

    PubMed

    Orihuela, A; Averós, X; Solano, J; Clemente, N; Estevez, I

    2016-03-01

    Reproduction in tropical sheep is not affected by season, whereas the reproductive cycle of temperate-climate breeds such as Suffolk depends on the photoperiod. Close contact with tropical ewes during the anestrous period might induce Suffolk ewes to cycle, making the use of artificial light or hormonal treatments unnecessary. However, the integration of both breeds within the social group would be necessary to trigger this effect, and so the aim of the experiment was to determine the speed of integration of 2 groups of Saint Croix and Suffolk ewes into a single flock, according to space allowance and previous experience. For this, 6 groups of 10 ewes (half from each breed) from both breeds, housed at 2 or 4 m/ewe (3 groups/treatment) and with or without previous contact with the other breed, were monitored for 3 d. Each observation day, the behavior, movement, and use of space of ewes were collected during 10 min at 1-h intervals between 0900 and 1400 h. Generalized linear mixed models were used to test the effects of breed, space allowance, and previous experience on behavior, movement, and use of space. Net distances, interbreed farthest neighbor distance, mean interbreed distance, and walking frequencies were greater at 4 m/ewe ( < 0.05). Intrabreed nearest neighbor, mean intrabreed neighbor, and interbreed nearest neighbor distances and minimum convex polygons at 4 m/ewe were greatest for Saint Croix ewes, whereas the opposite was found for lying down ( < 0.05). Experienced ewes showed larger intrabreed nearest neighbor distances, minimum convex polygons, and home range overlapping ( < 0.05). Experienced ewes at 4 m/ewe showed longest total distances and step lengths and greatest movement activity ( < 0.05). Experienced ewes walked longer total distances during Day 1 and 2 ( < 0.05). Lying down frequency was greater for Day 3 than Day 1 ( < 0.05), and Suffolk ewes kept longer interindividual distances during Day 1 ( < 0.05). After 3 d of cohabitation, Suffolk

  16. Pyrrolidinyl-camphor derivatives as a new class of organocatalyst for direct asymmetric Michael addition of aldehydes and ketones to beta-nitroalkenes.

    PubMed

    Ting, Ying-Fang; Chang, Chihliang; Reddy, Raju Jannapu; Magar, Dhananjay R; Chen, Kwunmin

    2010-06-18

    Practical and convenient synthetic routes have been developed for the synthesis of a new class of pyrrolidinyl-camphor derivatives (7 a-h). These novel compounds were screened as catalysts for the direct Michael addition of symmetrical alpha,alpha-disubstituted aldehydes to beta-nitroalkenes. When this asymmetric transformation was catalyzed by organocatalyst 7 f, the desired Michael adducts were obtained in high chemical yields, with high to excellent stereoselectivities (up to 98:2 diastereomeric ratio (d.r.) and 99 % enantiomeric excess (ee)). The scope of the catalytic system was expanded to encompass various aldehydes and ketones as the donor sources. The synthetic application was demonstrated by the synthesis of a tetrasubstituted-cyclohexane derivative from (S)-citronellal, with high stereoselectivity.

  17. STS-113 Crew Interviews: Michael Lopez-Alegria, Mission Specialist 1

    NASA Technical Reports Server (NTRS)

    2002-01-01

    STS-113 Mission Specialist 1 Michael Lopez-Alegria is seen during this preflight interview where he gives a quick overview of the mission before answering questions about his inspiration to become an astronaut and his career path. Lopez-Alegria outlines his role in the mission in general, and specifically during the docking and extravehicular activities (EVAs). He describes the payload (P1 truss) and the crew transfer activities (the crew of Expedition Six is replacing the crew of Expedition Five on the International Space Station (ISS)). Lopez-Alegria discusses the planned EVAs in detail and outlines what supplies will be left for the resident crew. He ends with his thoughts on the importance of the ISS as the second anniversary of human occupation of the Space Station approaches.

  18. Attending to hidden realities: contributions from the work of Michael Polanyi to supervision in pastoral care and counseling.

    PubMed

    Rodgerson, Thomas E

    2008-01-01

    In this article, the author suggests that concepts from the work of Michael Polanyi--such as the tacit dimension, subsidiary awareness, and commitment to a yet unrevealed, hidden reality--provide a theoretical basis for understanding the unique formation involved in pastoral care and counseling supervision.

  19. Ice Surface Morphology and Flow on Malaspina Glacier, Alaska: Implications for Regional Tectonics in the Saint Elias Orogen

    NASA Technical Reports Server (NTRS)

    Cotton, Michelle M.; Bruhn, Ronald L.; Sauber, Jeanne; Burgess, Evan; Forster, Richard R.

    2014-01-01

    The Saint Elias Mountains in southern Alaska are located at a structural syntaxis where the coastal thrust and fold belt of the Fairweather plate boundary intersects thrust faults and folds generated by collision of the Yakutat Terrane. The axial trace of this syntaxis extends southeastward out of the Saint Elias Mountains and beneath Malaspina Glacier where it is hidden from view and cannot be mapped using conventional methods. Here we examine the surface morphology and flow patterns of Malaspina Glacier to infer characteristics of the bedrock topography and organization of the syntaxis. Faults and folds beneath the eastern part of the glacier trend northwest and reflect dextral transpression near the terminus of the Fairweather fault system. Those beneath the western part of the glacier trend northeast and accommodate folding and thrust faulting during collision and accretion of the Yakutat Terrane. Mapping the location and geometry of the structural syntaxis provides important constraints on spatial variations in seismicity, fault kinematics, and crustal shortening beneath Malaspina Glacier, as well as the position of the collisional deformation front within the Yakutat Terrane. We also speculate that the geometrical complexity of intersecting faults within the syntaxis formed a barrier to rupture propagation during two regional Mw 8.1earthquakes in September 1899.

  20. Diagnosis: Michael Moore--media paint filmmaker to be health care system's main problem.

    PubMed

    Kao, Caroline

    2008-01-01

    The media reporting on Sicko, Michael Moore's documentary about the failures of the U.S. health care system, provides an example of how corporate media continue to twist and restrict the much-needed debate on health care reform. Aside from an occasional concession that having 46 million uninsured Americans is indeed problematic, the media's hype-filled conversation on health care avoids the issues and echoes old myths about the dangers of "government-run" and "socialized" health care. But in the face of the media demonization, universal health care is remarkably popular among the public.

  1. PREFACE: 2nd International School and Conference Saint-Petersburg OPEN on Optoelectronics, Photonics, Engineering and Nanostructures (SPbOPEN2015)

    NASA Astrophysics Data System (ADS)

    2015-11-01

    The 2nd International School and Conference ''Saint Petersburg OPEN 2015'' on Optoelectronics, Photonics, Engineering and Nanostructures was held on April 6 - 8, 2015 at St. Petersburg Academic University. The School and Conference included a series of invited talks given by leading professors with the aim to introduce young scientists with actual problems and major advances in physics and technology. The keynote speakers were Mikhail V. Maximov (Ioffe Physico-Technical Institute RAS, Russia) Vladimir G. Dubrovskii (St. Petersburg Academic University and St. Petersburg State University, Russia) Anton Yu. Egorov (JSC Connector Optics, Russia) Victor V. Luchinin (St. Petersburg State Electrotechnical University, Russia) Vladislav E. Bugrov (St. Petersburg University of Internet Technologies, Mechanics and Optics, Russia) Vitali A. Schukin (VI Systems, Germany) Yuri P. Svirko (University of Eastern Finland, Finland) During the poster session all undergraduate and graduate students attending the conference presented their works. A sufficiently large number of participants, with more than 170 student attendees from all over the world, allowed the Conference to provide a fertile ground for fruitful discussions between the young scientists as well as to become a perfect platform for valuable discussions between student authors and highly experienced scientists. The best student papers, which were selected by the Program Committee and by the invited speakers basing on the theses and their poster presentation, were awarded with diplomas of the conference - see the photos. This year ''Saint Petersburg OPEN 2015'' is organized by St. Petersburg Academic University in cooperation with Peter the Great St. Petersburg Polytechnic University. The School and Conference is supported by Russian Science Foundation, SPIE (The International Society for Optics and Photonics), OSA (The Optical Society) and by Skolkovo Foundation. It is a continuation of the annual schools and seminars for

  2. Official Portrait of Astronaut Michael Collins

    NASA Technical Reports Server (NTRS)

    1967-01-01

    This is the official NASA portrait of astronaut Michael Collins. Collins chose an Air Force career following graduation from West Point. He served as an experimental flight test officer at the Air Force Flight Test Center, Edwards Air Force Base, California, and, in that capacity, tested performance and stability and control characteristics of Air Force aircraft, primarily jet fighters. Having logged approximately 5,000 hours flying time, Collins was one of the third group of astronauts named by NASA in October 1963. Collins completed two space flights, logging 266 hours in space, of which, 1 hour and 27 minutes was spent in Extra Vehicular Activity (EVA). On July 18, 1966, he served as backup pilot for the Gemini VII mission which included a successful rendezvous and docking with a separately launched Agena target vehicle and, using the power of the Agena, maneuvered the Gemini spacecraft into another orbit for a rendezvous with a second, passive Agena. His skillful performance in completing two periods of EVA included the recovery of a micrometeorite detection experiment from the passive Agena. July 16-24, 1969, Collins served as command module (CM) pilot on Apollo 11, the historic first lunar landing mission. He remained aboard the CM, Columbia, on station in lunar orbit and performed the final re-docking maneuvers following a successful lunar orbit rendezvous with the Lunar Module (LM), Eagle. Collins left NASA in January 1970.

  3. N-heterocyclic carbene-catalyzed tandem aza-benzoin/Michael reactions: on site reversal of the reactivity of N-Boc imines.

    PubMed

    Wu, Ke-Jia; Li, Gong-Qiang; Li, Yi; Dai, Li-Xin; You, Shu-Li

    2011-01-07

    A tandem NHC-catalyzed aza-benzoin/Michael reaction has been developed as a method to efficiently produce dihydroindenones and pyrrolidinone-containing tricycles. The novel reaction pattern involves tert-butyl aryl(tosyl)methylcarbamates reacting as both electrophile and nucleophile on the same carbon.

  4. Jack Michael's Appointments at the University of Houston and Arizona State University: Reflections from a Former Student

    ERIC Educational Resources Information Center

    Mabry, John H.

    2016-01-01

    Jack Michael was an early enthusiast for what is now called applied behavior analysis. His many seminal contributions were through early publications in applied behavior analysis and the work of the students he trained (e.g., T. Ayllon, M. M. Wolf). His close mentorship of students earned him acclaim as a teacher along with his many theoretical…

  5. New Insights into Tectonics of the Saint Elias, Alaska, Region Based on Local Seismicity and Tomography

    NASA Astrophysics Data System (ADS)

    Ruppert, N. A.; Zabelina, I.; Freymueller, J. T.

    2013-12-01

    Saint Elias Mountains in southern Alaska are manifestation of ongoing tectonic processes that include collision of the Yakutat block with and subduction of the Yakutat block and Pacific plate under the North American plate. Interaction of these tectonic blocks and plates is complex and not well understood. In 2005 and 2006 a network of 22 broadband seismic sites was installed in the region as part of the SainT Elias TEctonics and Erosion Project (STEEP), a five-year multi-disciplinary study that addressed evolution of the highest coastal mountain range on Earth. High quality seismic data provides unique insights into earthquake occurrence and velocity structure of the region. Local earthquake data recorded between 2005 and 2010 became a foundation for detailed study of seismotectonic features and crustal velocities. The highest concentration of seismicity follows the Chugach-St.Elias fault, a major on land tectonic structure in the region. This fault is also delineated in tomographic images as a distinct contrast between lower velocities to the south and higher velocities to the north. The low-velocity region corresponds to the rapidly-uplifted and exhumed sediments on the south side of the range. Earthquake source parameters indicate high degree of compression and undertrusting processes along the coastal area, consistent with multiple thrust structures mapped from geological studies in the region. Tomographic inversion reveals velocity anomalies that correlate with sedimentary basins, volcanic features and subducting Yakutat block. We will present precise earthquake locations and source parameters recorded with the STEEP and regional seismic network along with the results of P- and S-wave tomographic inversion.

  6. Efficient analytical implementation of the DOT Riemann solver for the de Saint Venant-Exner morphodynamic model

    NASA Astrophysics Data System (ADS)

    Carraro, F.; Valiani, A.; Caleffi, V.

    2018-03-01

    Within the framework of the de Saint Venant equations coupled with the Exner equation for morphodynamic evolution, this work presents a new efficient implementation of the Dumbser-Osher-Toro (DOT) scheme for non-conservative problems. The DOT path-conservative scheme is a robust upwind method based on a complete Riemann solver, but it has the drawback of requiring expensive numerical computations. Indeed, to compute the non-linear time evolution in each time step, the DOT scheme requires numerical computation of the flux matrix eigenstructure (the totality of eigenvalues and eigenvectors) several times at each cell edge. In this work, an analytical and compact formulation of the eigenstructure for the de Saint Venant-Exner (dSVE) model is introduced and tested in terms of numerical efficiency and stability. Using the original DOT and PRICE-C (a very efficient FORCE-type method) as reference methods, we present a convergence analysis (error against CPU time) to study the performance of the DOT method with our new analytical implementation of eigenstructure calculations (A-DOT). In particular, the numerical performance of the three methods is tested in three test cases: a movable bed Riemann problem with analytical solution; a problem with smooth analytical solution; a test in which the water flow is characterised by subcritical and supercritical regions. For a given target error, the A-DOT method is always the most efficient choice. Finally, two experimental data sets and different transport formulae are considered to test the A-DOT model in more practical case studies.

  7. Progress in coherent lithography using table-top extreme ultraviolet lasers

    NASA Astrophysics Data System (ADS)

    Li, Wei

    Nanotechnology has drawn a wide variety of attention as interesting phenomena occurs when the dimension of the structures is in the nanometer scale. The particular characteristics of nanoscale structures had enabled new applications in different fields in science and technology. Our capability to fabricate these nanostructures routinely for sure will impact the advancement of nanoscience. Apart from the high volume manufacturing in semiconductor industry, a small-scale but reliable nanofabrication tool can dramatically help the research in the field of nanotechnology. This dissertation describes alternative extreme ultraviolet (EUV) lithography techniques which combine table-top EUV laser and various cost-effective imaging strategies. For each technique, numerical simulations, system design, experiment result and its analysis will be presented. In chapter II, a brief review of the main characteristics of table-top EUV lasers will be addressed concentrating on its high power and large coherence radius that enable the lithography application described herein. The development of a Talbot EUV lithography system which is capable of printing 50nm half pitch nanopatterns will be illustrated in chapter III. A detailed discussion of its resolution limit will be presented followed by the development of X-Y-Z positioning stage, the fabrication protocol for diffractive EUV mask, and the pattern transfer using self- developed ion beam etching, and the dose control unit. In addition, this dissertation demonstrated the capability to fabricate functional periodic nanostructures using Talbot EUV lithography. After that, resolution enhancement techniques like multiple exposure, displacement Talbot EUV lithography, fractional Talbot EUV lithography, and Talbot lithography using 18.9nm amplified spontaneous emission laser will be demonstrated. Chapter IV will describe a hybrid EUV lithography which combines the Talbot imaging and interference lithography rendering a high resolution

  8. Effective Integration of Technology and Instruction. Q&A with Michael Jay. REL Mid-Atlantic Educator Effectiveness Webinar Series

    ERIC Educational Resources Information Center

    Regional Educational Laboratory Mid-Atlantic, 2015

    2015-01-01

    In this webinar, long-time educator and developer of education technology Michael Jay discussed the importance of using technology to support learning and gave examples of how teachers can integrate technology into their instruction based on the Common Core State Standards and the Next Generation Science Standards. The PowerPoint presentation and…

  9. On the study of control effectiveness and computational efficiency of reduced Saint-Venant model in model predictive control of open channel flow

    NASA Astrophysics Data System (ADS)

    Xu, M.; van Overloop, P. J.; van de Giesen, N. C.

    2011-02-01

    Model predictive control (MPC) of open channel flow is becoming an important tool in water management. The complexity of the prediction model has a large influence on the MPC application in terms of control effectiveness and computational efficiency. The Saint-Venant equations, called SV model in this paper, and the Integrator Delay (ID) model are either accurate but computationally costly, or simple but restricted to allowed flow changes. In this paper, a reduced Saint-Venant (RSV) model is developed through a model reduction technique, Proper Orthogonal Decomposition (POD), on the SV equations. The RSV model keeps the main flow dynamics and functions over a large flow range but is easier to implement in MPC. In the test case of a modeled canal reach, the number of states and disturbances in the RSV model is about 45 and 16 times less than the SV model, respectively. The computational time of MPC with the RSV model is significantly reduced, while the controller remains effective. Thus, the RSV model is a promising means to balance the control effectiveness and computational efficiency.

  10. Historical sea level data rescue to assess long-term sea level evolution: Saint-Nazaire observatory (Loire estuary, France) since 1863.

    NASA Astrophysics Data System (ADS)

    Ferret, Yann; Voineson, Guillaume; Pouvreau, Nicolas

    2014-05-01

    Nowadays, the study of the global sea level rise is a strong societal concern. The analysis of historical records of water level proves to be an ideal way to provide relevant arguments regarding the observed trends. In France, many systematic sea level observations have taken place since the mid-1800s. Despite this rich history, long sea level data sets digitally available are still scarce. Currently, only the time series of Brest, Marseille and recently the composite one of the Pertuis d'Antioche span periods longer than a century and are available to be taken into account in studies dealing with long term sea-level evolution. In this context, an important work of "data archaeology" is undertaken to rescue the numerous existing analog historical data that is part of the French scientific and cultural heritage. The present study is focused on the measurements carried out at the sea level observatory of Saint-Nazaire, located on the French Atlantic coast in the Loire estuary mouth area. Measurements were automatically performed with the use of float tide gauges from 1863 to 2007, but include some important gaps between 1920 and 1950. Since 2007, the Saint-Nazaire observatory is part of the French RONIM network operated by SHOM, and the old mechanical tide gauge has been superseded by a radar tide gauge (operated by "Grand Port Maritime" of Nantes-Saint-Nazaire). In total, the covered period is up to 150-year-long, including at least 125 years of continuous sea level measurements. With the reconstruction of this new data set, we aim at improving our knowledge on trends in sea level components on the Atlantic coast on large scale and on the coast vulnerability at more local scale. Moreover, because of the location of the station, it should be possible as well to study the influence of the Loire River on water level since the 19th century. It has been shown that the tidal range was strongly modified during the last century because of the anthropogenic influence along

  11. Combining silver catalysis and organocatalysis: a sequential Michael addition/hydroalkoxylation one-pot approach to annulated coumarins.

    PubMed

    Hack, Daniel; Chauhan, Pankaj; Deckers, Kristina; Hermann, Gary N; Mertens, Lucas; Raabe, Gerhard; Enders, Dieter

    2014-10-03

    A highly stereoselective one-pot procedure for the synthesis of five-membered annulated hydroxycoumarins has been developed. By merging primary amine catalysis with silver catalysis, a series of functionalized coumarin derivatives were obtained in good yields (up to 91%) and good to excellent enantioselectivities (up to 99% ee) via a Michael addition/hydroalkoxylation reaction. Depending on the substituents on the enynone, the synthesis of annulated six-membered rings is also feasible.

  12. Sedimentary Records of Hyperpycnal Flows and the Influence of River Damming on Sediment Dynamics of Estuaries: Examples from the Nelson, Churchill, Moisie and Sainte-Marguerite Rivers (Canada)

    NASA Astrophysics Data System (ADS)

    St-Onge, G.; Duboc, Q.; Boyer-Villemaire, U.; Lajeunesse, P.; Bernatchez, P.

    2015-12-01

    Sediment cores were sampled in the estuary of the Nelson and Churchill Rivers in western Hudson Bay, as well as in the estuary of the Moisie and Sainte-Marguerite Rivers in Gulf of St. Lawrence in order to evaluate the impact of hydroelectric dams on the sedimentary regime of these estuaries. The gravity cores at the mouth of the Nelson River recorded several cm-thick rapidly deposited layers with a reverse to normal grading sequence, indicating the occurrence of hyperpycnal flows generated by major floods during the last few centuries. These hyperpycnal flows were probably caused by ice-jam formation, which can increase both the flow and the sediment concentration following the breaching of such natural dams. Following the construction of hydroelectric dams since the 1960s, the regulation of river discharge prevented the formation of hyperpycnal flows, and hence the deposition of hyperpycnites in the upper part of the cores. In the core sampled in the estuary of the Churchill River, only one hyperpycnite was recorded. This lower frequency may be due to the enclosed estuary of the Churchill River, its weaker discharge and the more distal location of the coring site.In the Gulf of St. Lawrence, grain size measurements allowed the identification of a major flood around AD 1844±4 years in box cores from both the Sainte-Marguerite and Moisie Rivers, whereas a drastic decrease in variations in the median grain size occurred around AD ~1900 in the estuary of the Sainte-Marguerite River, highlighting the offshore impact of the SM1 dam construction in the early 1900s. Furthermore, sedimentological variations in the box cores from both estuaries have been investigated by wavelet analysis and the sharp disappearance of high frequencies around AD 1900 in the estuary of the dammed river (Sainte-Marguerite River), but not in the estuary of the natural river (Moisie River), also provides evidence of the influence of dams on the sedimentary regime of estuaries.

  13. Tracer-dilution experiments and solute-transport simulations for a mountain stream, Saint Kevin Gulch, Colorado. Water resources investigation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Broshears, R.E.; Bencala, K.E.; Kimball, B.A.

    In 1986, the U.S. Geological Survey began an investigation to characterize within-stream hydrologic, chemical, and biological processes that influence the distribution and transport of hazardous constituents in the headwaters of the Arkansas River. The report describes the results of tracer-dilution experiments and associated solute-transport simulations for a 1804-meter stretch of Saint Kevin Gulch, a stream affected by acid mine drainage in Lake County, Colorado. The report describes transient changes in tracer (lithium chloride) concentration at six instream sites.

  14. Late Quaternary vegetation and climate history of the central Bering land bridge from St. Michael Island, western Alaska

    USGS Publications Warehouse

    Ager, T.A.

    2003-01-01

    Pollen analysis of a sediment core from Zagoskin Lake on St. Michael Island, northeast Bering Sea, provides a history of vegetation and climate for the central Bering land bridge and adjacent western Alaska for the past ???30,000 14C yr B.P. During the late middle Wisconsin interstadial (???30,000-26,000 14C yr B.P.) vegetation was dominated by graminoid-herb tundra with willows (Salix) and minor dwarf birch (Betula nana) and Ericales. During the late Wisconsin glacial interval (26,000-15,000 14C yr B.P.) vegetation was graminoid-herb tundra with willows, but with fewer dwarf birch and Ericales, and more herb types associated with dry habitats and disturbed soils. Grasses (Poaceae) dominated during the peak of this glacial interval. Graminoid-herb tundra suggests that central Beringia had a cold, arid climate from ???30,000 to 15,000 14C yr B.P. Between 15,000 and 13,000 14C yr B.P., birch shrub-Ericales-sedge-moss tundra began to spread rapidly across the land bridge and Alaska. This major vegetation change suggests moister, warmer summer climates and deeper winter snows. A brief invasion of Populus (poplar, aspen) occurred ca. 11,000-9500 14C yr B.P., overlapping with the Younger Dryas interval of dry, cooler(?) climate. During the latest Wisconsin to middle Holocene the Bering land bridge was flooded by rising seas. Alder shrubs (Alnus crispa) colonized the St. Michael Island area ca. 8000 14C yr B.P. Boreal forests dominated by spruce (Picea) spread from interior Alaska into the eastern Norton Sound area in middle Holocene time, but have not spread as far west as St. Michael Island. ?? 2003 University of Washington. Published by Elsevier Inc. All rights reserved.

  15. Perspectives on the New Orleans Saints as a Vehicle for the Installation of Hope, Post Katrina: Therapy on the 30 Yard Line

    ERIC Educational Resources Information Center

    Lawrence, Christopher

    2007-01-01

    The author discusses the effectiveness of popular culture as a tool for the instillation of hope within a community, using as an example the ways in which a National Football League team galvanized the residents of New Orleans in the 18 months following Hurricane Katrina. This article posits that the Saints supplied an impetus for transcendence…

  16. What I Think I May Have Learned--Reflections on 50 Years of Teaching: An Interview with Michael Wertheimer

    ERIC Educational Resources Information Center

    Michael, Kurt D.

    2006-01-01

    Kurt Michael is an associate professor in the Department of Psychology at Appalachian State University (ASU) where he teaches history and systems of psychology, abnormal psychology, child psychopathology, and interventions for children and adolescents. He received his BA (cum laude) from the University of Colorado at Boulder and his MS and PhD in…

  17. Magnetic mapping around Les Saintes islands (Lesser Antilles, Guadeloupe) for structural interpretation

    NASA Astrophysics Data System (ADS)

    Mercier de Lépinay, J.; Munschy, M.; Géraud, Y.; Diraison, M.; Navelot, V.; Verati, C.; Corsini, M.; Lardeaux, J. M.

    2016-12-01

    In Les Saintes archipelago, the outcrop analysis of Terre-de-Haut island allows to point out several fault systems and geological objects such as lava domes and lava flows. Moreover an exhumed geothermal paleo-system was identified and is thought to be an interesting analogue of the active geothermal system of Bouillante, Guadeloupe. To fully understand this area, the offshore continuation of the geological features is a major concern. The previously known onshore features are visible on airborne magnetic maps due to the highly magnetized material in Les Saintes archipelago. Moreover hydrothermal processes alter the magnetized minerals of volcanic rocks, creating a significant variation in the magnetic measurements. Therefore an adapted marine magnetic study can help the geological understanding of this particular area. In order to correctly link the offshore and onshore structures, the magnetic survey must be close enough to the shoreline and detailed enough so as to correctly outline the tectonic structures. An appropriate solution for such a survey was to use a magnetometer aboard a speedboat. Such a boat allows more navigation flexibility than a classic oceanic vessel towing a magnetometer; it can sail at higher speed on calm seas and closer to the shoreline. This kind of set up is only viable because the magnetic effect of the ship can be compensated using the same algorithms than those used for airborne magnetometry. Studies were implemented through the GEOTREF program which benefits from the support of both the ADEME and the French public funds "Investments for the future". The use of magnetic field transformations allows a large variety of structures to be highlighted, providing insights that help to build a general understanding of the nature and distribution of the magnetic sources. Using a reduction to the pole map operator we are able to prolong the volcanic structures at sea. The marine part of the paleo-geothermal system extension is also roughly

  18. An improved procedure to prepare 3-methyl-4-nitroalkylenethylisoxazoles and their reaction under catalytic enantioselective Michael addition with nitromethane.

    PubMed

    Moccia, Maria; Wells, Robert J; Adamo, Mauro F A

    2015-02-21

    Herein, we describe a short synthesis of 3-methyl-4-nitro-5-alkylethenyl isoxazoles and their reactivity as Michael acceptors. The title compounds reacted with nitromethane under phase-transfer catalysis to provide highly enantioenriched adducts (up to 93% ee) which were then converted to the corresponding γ-nitroacids.

  19. Diastereoselective auxiliary- and catalyst-controlled intramolecular aza-Michael reaction for the elaboration of enantioenriched 3-substituted isoindolinones. Application to the synthesis of a new pazinaclone analogue

    PubMed Central

    Sallio, Romain; Lebrun, Stéphane; Capet, Frédéric; Agbossou-Niedercorn, Francine

    2018-01-01

    A new asymmetric organocatalyzed intramolecular aza-Michael reaction by means of both a chiral auxiliary and a catalyst for stereocontrol is reported for the synthesis of optically active isoindolinones. A selected cinchoninium salt was used as phase-transfer catalyst in combination with a chiral nucleophile, a Michael acceptor and a base to provide 3-substituted isoindolinones in good yields and diastereomeric excesses. This methodology was applied to the asymmetric synthesis of a new pazinaclone analogue which is of interest in the field of benzodiazepine-receptor agonists. PMID:29623121

  20. A Philosophy of Jewish Education in Question Marks: A Possible Reading of Michael Rosenak's Last Speech

    ERIC Educational Resources Information Center

    Rosenak, Avinoam

    2014-01-01

    Writing this article presents me with an opportunity to look closely at the last speech that my father and mentor, Professor Michael (Mike) Rosenak z"l gave before his passing in 2013. I will write about this speech from a perspective that is based on my intimate familiarity with the questions that concerned him throughout his life. I will…

  1. Michael Francis Madelin (1931--2007): a pioneer in the biology and ecology of conidial fungi and slime moulds.

    PubMed

    Campbell, Richard

    2008-12-01

    Michael F Madelin (1931--2007) was Programme Secretary, Vice-President, and President of the British Mycological Society. A summary of his research on Coprinopsis, various conidial fungi, Coelomomyces and myxomycetes is presented, with a full list of his publications. His teaching career was initially at Imperial College, University of London, and then mostly at the University of Bristol.

  2. A Symposium on the Relevance of Michael Polanyi's Insights to a Reformulated Understanding of Science, Technology, and Society

    ERIC Educational Resources Information Center

    Mead, Walter B.

    2011-01-01

    This is intended as an introductory statement to the explorations undertaken in the essays that follow. The authors of these essays attempt to introduce the reader to some of the insights of Michael Polanyi and their implications for the reader who wishes to come to a greater understanding of modern technological society, which--for better or…

  3. Translation to Spanish and Validation of the Specific Saint George's Questionnaire for Idiopathic Pulmonary Fibrosis.

    PubMed

    Capparelli, Ignacio; Fernandez, Martín; Saadia Otero, Marcela; Steimberg, Jimena; Brassesco, María; Campobasso, Ana; Palacios, Sandra; Caro, Fabian; Alberti, María Laura; Rabinovich, Roberto A; Paulin, Francisco

    2018-02-01

    Interstitial lung disease (ILD) is associated with low exercise tolerance, dyspnea, and decreased health-related quality of life (HRQL). Idiopathic pulmonary fibrosis (IPF) is one of the most prevalent in the group. A specific version of the Saint George's questionnaire (SGRQ-I) has been developed to quantify the HRQL of IPF patients. However, this tool is not currently validated in the Spanish language. The objective was to translate into Spanish and validate the specific Saint George's Respiratory Questionnaire for idiopathic pulmonary fibrosis (SGRQ-I). The repeatability, internal consistency and construct validity of the SGRQ-I in Spanish were analyzed after a backtranslation process. In total, 23 outpatients with IPF completed the translated SGRQ-I twice, 7 days apart. Repeatability was studied, revealing good concordance in test-retest with an ICC (interclass correlation coefficient) of 0.96 (P<.001). Internal consistency was good for different questionnaire items (Cronbach's alpha of 0.9 including and 0.81 excluding the total value) (P<.001). The total score of the questionnaire showed good correlation with forced vital capacity FVC% (r=-0.44; P=.033), diffusing capacity of the lungs for carbon monoxide (DL CO %) (r=-0.55; P=.011), partial pressure of oxygen in arterial blood PaO 2 (r=-0.44; P=.036), Medical Research Council Dyspnea scale (r=-0.65; P<.001), and number of steps taken in 24hours (r=-0.47; P=.024). The Spanish version of SGRQ-Ideveloped by our group shows good internal consistency, reproducibility and validity, so it can be used for the evaluation of quality of life (QOL) in IPF patients. Copyright © 2017 SEPAR. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. [Early career of Michael Sendivogius].

    PubMed

    Prinke, Rafał T

    2012-01-01

    One of the most influential alchemical authors of the early modern period was Michael Sendivogius whose early life is shrouded in mystery. He may be labelled the most famous Polish scientific writer between Copernicus and Marie Skłodowska-Curie, but because of the difficulties involved in researching the biography of any alchemist, there has been relatively little interest in him among Polish historians. The early work of Roman Bugaj (author of the still fundamental monograph) and Włodzimierz Hubicki (who made his research available to the international community) has been continued only by the English-born Zbigniew Szydło and the author of this article. The roots of many legends about Sendivogius were three mid-17th century short biographies, none of which is trustworthy, so it is crucial to verify the received myth and the version constructed in the 1960's and 1970's with primary sources and evidence from the recent "new historiography of alchemy". The present article examines them in the light of newly discovered sources and reinterpretation of the old ones. The genealogy of the Sedzimir family is discussed at length to show that Sendivogius most probably was not its member but only a pretender in order to assume (or prove) the status of a nobleman. Several possible hypotheses about his origins are presented. He is known to have studied at three universities (Leipzig, Vienna and Altdorf) but authors of early panegyrics dedicated to Sendivogius list more universities which he may have attended. The most interesting is that of Cambridge, listed as the first one, because practically no Poles or Czechs went there at the time. Finally, his marriage to Veronica Stiebar, a wealthy widow of a Franconian knightly family, and her interesting family relationships (links to Erasmus, Camerarius, Paracelsus and the original Doctor Faustus) are discussed. The period covered is that before Sendivogius moved to Prague in about 1597, having already been a courtier of Rudolf II

  5. Architecture, religion, and tuberculosis in Sainte-Agathe-des-Monts, Quebec.

    PubMed

    Adams, Annmarie; Poutanen, Mary Anne

    2009-01-01

    This paper explores the architecture of the Mount Sinai Sanatorium in Sainte-Agathe-des-Monts (Qc) to disentangle the role of religion in the treatment of tuberculosis. In particular, we analyze the design of Mount Sinai, the jewel in the crown of Jewish philanthropy in Montreal, in relation to that of the nearby Laurentian Sanatorium. While Mount Sinai offered free treatment to the poor in a stunning, Art Deco building of 1930, the Protestant hospital had by then served paying patients for more than two decades in a purposefully home-like, Tudor-revival setting. Using architectural historian Bernard Herman's concept of embedded landscapes, we show how the two hospitals differed in terms of their relationship to site, access, and, most importantly, to city, knowledge, and community. Architects Scopes & Feustmann, who designed the Laurentian hospital, operated an office at Saranac Lake, New York, America's premier destination for consumptives. The qualifications of Mount Sinai architects Spence & Goodman, however, derived from their experience with Jewish institutions in Montreal. Following Herman's approach to architecture through movement and context, how did notions of medical therapy and Judaism intersect in the plans of Mount Sinai?

  6. Michael Hauskeller: Sex and the Posthuman Condition : Palgrave-Macmillan, 2014, 98 pp.

    PubMed

    Miller, Lantz Fleming

    2016-10-01

    This new book from Michael Hauskeller explores the currently marketed or projected sex/love products that exhibit some trait of so-called "posthumanistic" theory or design. These products are so designated because of their intention to fuse high technologies, including robotics and computing, with the human user. The author offers several arguments for why the theory behind these products leads to inconsistencies. The book uses a unique approach to philosophical argument by enmeshing the argument's major points in a concomitant discussion of pieces from world literature pertaining to posthumanism. The method is compelling, heightened by great world authorial insights that rarely find their way into philosophy and shores up some strong argumentative points. Yet some of the argument still needs more elucidating.

  7. Efficient synthesis of optically active 4-nitro-cyclohexanones via bifunctional thiourea-base catalyzed double-Michael addition of nitromethane to dienones.

    PubMed

    Wu, Bin; Liu, Guo-Gui; Li, Mei-Qiu; Zhang, Yong; Zhang, Shao-Yun; Qiu, Jun-Ru; Xu, Xiao-Ping; Ji, Shun-Jun; Wang, Xing-Wang

    2011-04-07

    Thiourea-modified cinchona alkaloids as bifunctional catalysts and a base could catalyze a stepwise [5+1] cyclization of divinyl ketones with nitromethane via double Michael additions, furnishing optically active 4-nitro-cyclohexanones with good yields, excellent diastereoselectivities (>20 : 1) and high enantiomeric ratios (up to 97 : 3).

  8. From Hillforts to Saints: Sun Tropoi and Patterns of Christianization in NW Spain

    NASA Astrophysics Data System (ADS)

    Quintela, Marco V. García; García, A. César González; Veiga, Yolanda Seoane

    2015-05-01

    We present three Iron Age landscapes in the province of Ourense (northwest Spain), consisting of a hill fort with an acropolis used for religious purposes, and an "extra-urban" location used for ritual functions. Both locations are associated with the solstices, corroborating the validity of considering them jointly in each case, and the three cases jointly as a model. In the three locations, the oldest Christian saints and festivals we are able to identify re-use the dates of the solstices, and others, marked by Iron Age monuments. These observations open the way for research in several directions: the definition of religious landscapes from the Iron Age; the reason why there is not a 'Roman landscape'; the relationship between the Indo-European legacy and the introduction of Christianity; and the relationship between local calendars and the Celtic, Julian and Gregorian 'cultural' calendars.

  9. Michael Addition Polymerization of Trifunctional Amine and Acrylic Monomer: A Versatile Platform for Development of Biomaterials.

    PubMed

    Cheng, Weiren; Wu, Decheng; Liu, Ye

    2016-10-10

    Michael addition polymerizations of amines and acrylic monomers are versatile approaches to biomaterials for various applications. A combinatorial library of poly(β-amino ester)s and diverse poly(amido amine)s from diamines and diacrylates or bis(acrylamide)s have been reported, respectively. Furthermore, novel linear and hyperbranched polymers from Michael addition polymerizations of trifunctional amines and acrylic monomers significantly enrich this category of biomaterials. In this Review, we focus on the biomaterials from Michael addition polymerizations of trifunctional amines and acrylic monomers. First we discuss how the polymerization mechanisms, which are determined by the reactivity sequence of the three types of amines of trifunctional amines, i.e., secondary (2°) amines (original), primary (1°) amines, and 2° amines (formed), are affected by the chemistry of monomers, reaction temperature, and solvent. Then we update how to design and synthesize linear and hyperbranched polymers based on the understanding of polymerization mechanisms. Linear polymers containing 2° amines in the backbones can be obtained from polymerizations of diacrylates or bis(acrylamide)s with equimolar trifunctional amine, and several approaches, e.g., 2A 2 +BB'B″, A 3 +2BB'B', A 2 +BB'B″, to hyperbranched polymers are developed. Further through molecular design of monomers, conjugation of functional species to 2° amines in the backbones of linear polymers and the abundant terminal groups of hyperbranched polymers, the amphiphilicity of polymers can be adjusted, and additional stimuli, e.g., thermal, redox, reactive oxidation species (ROS), and light, responses can be integrated with the intrinsic pH response. Finally we discuss the applications of the polymers for gene/drug delivery and bioimaging through exploring their self-assemblies in various motifs, e.g., micelles, polyplexes particles/nanorings and hydrogels. Redox-responsive hyperbranched polymers can display 300

  10. A study of temporal dynamics and spatial variability of power frequency electromagnetic fields in Saint-Petersburg

    NASA Astrophysics Data System (ADS)

    Sturman, V. I.

    2018-01-01

    This paper studies spatial distribution and temporal dynamics of power frequency electric and magnetic fields in Saint-Petersburg. It was determined that sanitary-protection and exclusion zones of the standard size high-voltage transmission lines (HVTL) do not always ensure maximum allowable limits of the electrical field depression. A dependence of the electric field strength on meteorological factors was defined. A series of sources create a city-wide background for magnetic fields. That said, the heavier the man-caused load is, the higher the mean values of magnetic induction are. Abnormally high values of magnetic induction are explained by the influence of underground electric cables.

  11. Saint Louis Center for Sustainment of Trauma and Readiness Skills: A Collaborative Air Force-Civilian Trauma Skills Training Program

    DTIC Science & Technology

    2016-05-19

    NUMBER 6. AUTHOR(S) Jason W. Grimm , Karen Johnson 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION...ABSTRACT SAR 18. NUMBER OF PAGES 5 19a. NAME OF RESPONSIBLE PERSON Jason Grimm a. REPORT U b. ABSTRACT U c. THIS PAGE U 19b... Grimm Karen Johns For correspo Vista at Gra J Emerg Nu 0099-1767 Published b http://dx.do ■ ■ • ■SAINT LOUIS CENTER FOR SUSTAINMENT OF TRAUMA AND

  12. Race, punishment, and the Michael Vick experience.

    PubMed

    Piquero, Alex R; Piquero, Nicole Leeper; Gertz, Marc; Baker, Thomas; Batton, Jason; Barnes, J C

    2011-01-01

    Objective. The relationship between race and crime has been contentious, focusing primarily on offending and incarceration patterns among minorities. There has been some limited work on public perceptions of criminal punishment, and findings show that while minorities believe in the role and rule of law, they simultaneously perceive the justice system as acting in a biased and/or unfair manner. Two limitations have stalled this literature. First, research has focused mainly on criminal punishments to the neglect of noncriminal punishments. Second, most studies have not examined whether race remains salient after considering other demographic variables or discrimination and legitimacy attitudes.Methods. Using data from 400 adults, we examine how race affects perceptions of criminal punishment and subsequent reinstatement into the National Football League in the case of Michael Vick, a star professional quarterback who pled guilty to charges of operating an illegal dog-fighting ring.Results. Findings show that whites are more likely to view Vick's punishment as too soft and that he should not be reinstated, while nonwhites had the opposite views. Race remained significant after controlling for other variables believed to be related to punishment perceptions.Conclusion. Attitudes toward both criminal punishment and NFL reinstatement vary across race such that there exists important divides in how individuals perceive the system meting out punishment and subsequently reintegrating offenders back into society. These results underscore that white and nonwhites perceive the law and its administration differently.

  13. Michelangelo, the Last Judgment fresco, Saint Bartholomew and the Golden Ratio.

    PubMed

    de Campos, Deivis; Malysz, Tais; Bonatto-Costa, João Antonio; Pereira Jotz, Geraldo; Pinto de Oliveira Junior, Lino; Oxley da Rocha, Andrea

    2015-11-01

    Art and anatomy were particularly closely intertwined during the Renaissance period and numerous painters and sculptors expressed themselves in both fields. Among them was Michelangelo Buonarroti (1475-1564), who is renowned for having produced some of the most famous of all works of art, the frescoes on the ceiling and on the wall behind the altar of the Sistine Chapel in Rome. Recently, a unique association was discovered between one of Michelangelo's most celebrated works (The Creation of Adam fresco) and the Divine Proportion/Golden Ratio (GR) (1.6). The GR can be found not only in natural phenomena but also in a variety of human-made objects and works of art. Here, using Image-Pro Plus 6.0 software, we present mathematical evidence that Michelangelo also used the GR when he painted Saint Bartholomew in the fresco of The Last Judgment, which is on the wall behind the altar. This discovery will add a new dimension to understanding the great works of Michelangelo Buonarroti. © 2015 Wiley Periodicals, Inc.

  14. Ecology of Bats, Their Ectoparasites, and Associated Pathogens on Saint Kitts Island.

    PubMed

    Reeves, Will K; Beck, Jason; Orlova, Maria V; Daly, Jennifer L; Pippin, Kristi; Revan, Floyd; Loftis, Amanda D

    2016-06-09

    Ectoparasites of bats and bat-associated pathogens are poorly studied in the Lesser Antilles Islands. We report on an 11-mo field study on Saint Kitts Island of bat populations, their associated ectoparasites, and pathogens. We report on five ectoparasite species, including four Streblidae (Diptera) and a Spinturnicidae (Acari). Several genotypes of unnamed Bartonella were isolated from bats and ectoparasites. Microfilaria of an undetermined Litomosoides spp. were detected in blood from Artibeus jamaicensis Leach (Chiroptera: Phyllostomidae) (and associated ectoparasites: Trichobius intermedius Peterson and Hurka (Diptera: Streblidae) and Periglischrus iheringi Oudemans (Acari: Spinturnicidae)). In addition, an Ehrlichia sp. and Rickettsia africae were detected in the blood of several bat species. Our study is one of the first surveys of ectoparasite-borne pathogens in wild mammals from St. Kitts. Published by Oxford University Press on behalf of Entomological Society of America 2016. This work is written by US Government employees and is in the public domain in the United States.

  15. Flooding Risk Assessment for the Region of Neva Bay and Saint-Petersburg

    NASA Astrophysics Data System (ADS)

    Koch, A.; Nikitin, O.

    2006-12-01

    Sea level evaluations in the region of Saint-Petersburg, Russia, well known as "Neva Flooding" is the great scientific problem. This process has been investigated by various researchers for many tens of years. But they have not come to consideration regarding its nature. There are numerous factors responsible to extreme sea level rise in this location, and it is impossible to assess properly their individual and combine effect. In this Abstract the approach and primary results of the work are given. We tried to solve the task of flooding risk assessment in Neva Bay and Saint-Petersburg from the probability theory point of view. Sea level rise is considered as a stochastic process. To assess probable risk of a flooding the statistical game theory is used. There are two players in common statistical game. Each of them has the set of strategies that are used in the game. Who fails must pay. In our case one player is the Nature and the other is the Oceanographer, he chooses certain strategy to avoid flood consequences or minimize them. The Nature is the irrational and unpredictable player who has infinity set of strategies or certain conditions. But the choose of a condition is the subject of Monte Carlo model, and the Oceanographer can obtain some information about this model or Nature's behavior, that determined by the probability distribution of Nature's conditions. The main Oceanographer task is to take an optimal policy for various coastal objects regarding their protection characteristics, so that from one hand do not lose in quality and, from the other hand, do not raise its price. The policies are found out depending on some parameter that determined by the Nature condition. In our task this parameter is the evaluation of sea level near the coastal object. For the Nature condition we assumed the integral atmospheric characteristic that most completely expresses the synoptic state responsible for flooding. This characteristic includes all the cyclone parameters

  16. Preliminary physical stratigraphy, biostratigraphy, and geophysical data of the USGS South Dover Bridge Core, Talbot County, Maryland

    USGS Publications Warehouse

    Alemán González, Wilma B.; Powars, David S.; Seefelt, Ellen L.; Edwards, Lucy E.; Self-Trail, Jean M.; Durand, Colleen T.; Schultz, Arthur P.; McLaughlin, Peter P.

    2012-01-01

    The South Dover Bridge (SDB) corehole was drilled in October 2007 in Talbot County, Maryland. The main purpose for drilling this corehole was to characterize the Upper Cretaceous and Paleogene lithostratigraphy and biostratigraphy of the aquifers and confining units of this region. The data obtained from this core also will be used as a guide to geologic mapping and to help interpret well data from the eastern part of the Washington East 1:100,000-scale map near the town of Easton, Md. Core drilling was conducted to a depth of 700 feet (ft). The Cretaceous section was not penetrated due to technical problems during drilling. This project was funded by the U.S. Geological Survey’s (USGS) Eastern Geology and Paleoclimate Science Center (EGPSC) as part of the Geology of the Atlantic Watersheds Project; this project was carried out in cooperation with the Maryland Geological Survey (MGS) through partnerships with the Aquifer Characterization Program of the USGS’s Maryland-Delaware-District of Columbia Water Science Center and the National Cooperative Geologic Mapping Program. The SDB corehole was drilled by the USGS drilling crew in the northeastern corner of the Trappe 7.5-minute quadrangle, near the type locality of the Boston Cliffs member of the Choptank Formation. Geophysical logs (gamma ray, single point resistance, and 16-inch and 64-inch normal resistivity) were run to a depth of 527.5 ft; the total depth of 700.0 ft could not be reached because of the collapse of the lower part of the hole. Of the 700.0 ft drilled, 531.8 ft of core were recovered, representing a 76 percent core recovery. The elevation of the top of the corehole is approximately 12 ft above mean sea level; its coordinates are lat 38°44′49.34″N. and long 76°00′25.09″W. (38.74704N., 76.00697W. in decimal degrees). A groundwater monitoring well was not installed at this site. The South Dover Bridge corehole was the first corehole that will be used to better understand the geology and

  17. Ideal Teaching: Exploring the Attributes of an "Ideal Teacher" in the Church Educational System for the Church of Jesus Christ of Latter-Day Saints

    ERIC Educational Resources Information Center

    Strader, Matthew W.

    2009-01-01

    The purpose of this study was to identify the profile of an ideal teacher for the Church Educational System (CES) for the Church of Jesus Christ of Latter-day Saints. This study surveyed 159 students, teachers, and administrators in order to find the characteristics perceived to be ideal in a CES teacher. The survey included 16 characteristics of…

  18. Monitoring Persistent Volcanic Emissions from Sulphur Springs, Saint Lucia: A Community Approach to Disaster Risk Reduction

    NASA Astrophysics Data System (ADS)

    Joseph, E. P.; Beckles, D. M.; Cox, L.; Jackson, V. B.; Alexander, D.

    2014-12-01

    Volcanic and geothermal emissions are known natural sources of volatiles to the atmosphere. Volcanogenic air pollutants known to cause the most serious impact are carbon dioxide (CO2), sulphur dioxide (SO2), hydrogen chloride (HCl) and hydrogen fluoride (HF). Some studies into the potential for volcanic emissions to produce chronic diseases in humans indicate that areas of major concern include respiratory problems, particularly silicosis (Allen et al. 2000; Baxter et al. 1999; Buist et al. 1986), psychological stress (Shore et al. 1986), and chemical impacts of gas or ash (Giammanco et al. 1998). Sulphur Springs Park in Saint Lucia has a very high recreational value with >200,000 visitors annually, while the nearby town of Soufrière has >8,400 residents. Residents and visitors have raised concerns about the volcanic emissions and its health effects. As part of the volcanic surveillance programme undertaken by the UWI, Seismic Research Centre (SRC) in Saint Lucia, a new monitoring network has been established for quantifying the ambient SO2 in air, to which staff and visitors at the volcanic park are exposed to. The implementation and continued operation of this network has involved the training of local personnel in the active field sampling and analytical techniques required for the assessment of ambient SO2 concentrations, using a low cost monitor as well as commercial passive samplers. This approach recognizes that environmental hazards are a usual part of life and productive livelihoods, and to minimize post-disaster response and recovery it is beneficial to promote preparedness and mitigation, which is best achieved at the local level with community involvement. It is also intended that the volcanic emissions monitoring network could be used as a method to establish and maintain community-based initiatives that would also be helpful when volcanic threat manifests.

  19. Fostering Ecological Literacy: A Case Study of the Saint John Harbour in Two High School English Language Arts Classrooms

    NASA Astrophysics Data System (ADS)

    Douglas, Velta

    Integrating environmental education into curriculum in a way that tackles the holistic and complicated nature of multi-dimensional issues continues to be a challenge for educators and administrators. There is potential in using ecological literacy to introduce local environmental case studies into English Language Arts high school classrooms. This research examines the experiences of two ELA classrooms in one Saint John, NB, high school with a two-week unit based on stakeholder relationships within the Saint John Harbour. Through presentations by guest speakers and research sourced from local community groups, students learned about the highly complex environmental issues that inform management decisions for the Harbour. Using these materials as background, students participated in a mock stakeholders meeting. Case study methodology was used to explore student learning in both a higher-level and a lower-level grade 10 ELA class. Data for the analysis included: cognitive mapping exercises; oral and written classroom assignments and activities; a videotape of the mock stakeholder meetings; a focus group interview with selected students; and researcher field notes. Data demonstrated significant student learning about environmental issues including increased sophistication in describing links between and among environmental issues affecting the harbour, and much more complex understandings of the positions and roles of the various stakeholder groups. Some important areas of resistance to new learning were also evident. Implications for practice and policy and recommendations for future research are discussed.

  20. [Management of medical care for the victims of road accidents in traumatology centers of Saint-Petersburg].

    PubMed

    Tulupov, A N; Afonchikov, V Iu; Chikin, A E; Taniia, S Sh; Ganin, A S

    2014-01-01

    The number of road accidents, fatal outcomes and victims exceeded in 1.5 times in Saint-Petersburg in comparison with Moscow. At the average, 600 victims were treated in each of 6 first-level traumatology centers every year. The quantity of patients, who were admitted to 3 second-level traumatology centers, numbered 10 times less. About 300 people entered to others hospitals. The lethality consisted of 15%, 20% and 37%, respectively. There are a lot of matters, that should be discussed, such as an importance of better treatment financing of multitrauma by using compulsory medical insurance system, an optimization of pre-admission treatment and a necessity of patient delivery by mobile medical team using the anaesthesiology and resuscitation.

  1. Transformation of light double cones in the human retina: the origin of trichromatism, of 4D-spatiotemporal vision, and of patchwise 4D Fourier transformation in Talbot imaging

    NASA Astrophysics Data System (ADS)

    Lauinger, Norbert

    1997-09-01

    The interpretation of the 'inverted' retina of primates as an 'optoretina' (a light cones transforming diffractive cellular 3D-phase grating) integrates the functional, structural, and oscillatory aspects of a cortical layer. It is therefore relevant to consider prenatal developments as a basis of the macro- and micro-geometry of the inner eye. This geometry becomes relevant for the postnatal trichromatic synchrony organization (TSO) as well as the adaptive levels of human vision. It is shown that the functional performances, the trichromatism in photopic vision, the monocular spatiotemporal 3D- and 4D-motion detection, as well as the Fourier optical image transformation with extraction of invariances all become possible. To transform light cones into reciprocal gratings especially the spectral phase conditions in the eikonal of the geometrical optical imaging before the retinal 3D-grating become relevant first, then in the von Laue resp. reciprocal von Laue equation for 3D-grating optics inside the grating and finally in the periodicity of Talbot-2/Fresnel-planes in the near-field behind the grating. It is becoming possible to technically realize -- at least in some specific aspects -- such a cortical optoretina sensor element with its typical hexagonal-concentric structure which leads to these visual functions.

  2. Michael Novak's "Business as a Calling" as a Vehicle for Addressing Ethical and Policy Concerns in a Business Law Course

    ERIC Educational Resources Information Center

    Murphy, Tonia Hap

    2008-01-01

    This article describes the author's experience of incorporating Michael Novak's "Business as a Calling: Work and the Examined Life" into a Business Law course. The author views it as a positive addition to the course, one that may be of interest to her colleagues at other institutions. Accordingly, after an overview of Novak's analysis in…

  3. Tandem Aldol-Michael Reactions in Aqueous Diethylamine Medium: A Greener and Efficient Approach to Bis-Pyrimidine Derivatives

    PubMed Central

    Al-Majid, Abdullah M.; Barakat, Assem; AL-Najjar, Hany J.; Mabkhot, Yahia N.; Ghabbour, Hazem A.; Fun, Hoong-Kun

    2013-01-01

    A simple protocol, involving the green synthesis for the construction of novel bis-pyrimidine derivatives, 3a–i and 4a–e are accomplished by the aqueous diethylamine media promoted tandem Aldol-Michael reaction between two molecules of barbituric acid derivatives 1a,b with various aldehydes. This efficient synthetic protocol using an economic and environmentally friendly reaction media with versatility and shorter reaction time provides bis-pyrimidine derivatives with high yields (88%–99%). PMID:24317435

  4. A geologic guide to Wrangell-Saint Elias National Park and Preserve, Alaska; a tectonic collage of northbound terranes

    USGS Publications Warehouse

    Winkler, Gary R.; with contributions by MacKevett, E. M.; Plafker, George; Richter, D.H.; Rosenkrans, D.S.; Schmoll, H.R.

    2000-01-01

    Wrangell-Saint Elias National Park and Preserve, the largest unit in the U.S. National Park System, encompasses near 13.2 million acres of geological wonderments. This geologic guide presents history of exploration and Earth-science investigation; describes the complex geologic makeup; characterizes the vast college of accretion geologic terranes in this area of Alaska's continental margin; recapitulates the effects of earthquakes, volcanoes, and glaciers; characterizes the copper and gold resources of the parklands; and describes outstanding locales within the park and preserve area. A glossary of geologic terms and a categorized list of additional sources of information complete this report.

  5. Survival resonances in an atom-optics system driven by temporally and spatially periodic dissipation

    NASA Astrophysics Data System (ADS)

    Chai, Shijie; Fekete, Julia; McDowall, Peter; Coop, Simon; Lindballe, Thue; Andersen, Mikkel F.

    2018-03-01

    We investigate laser-cooled atoms periodically driven by pulsed standing waves of light tuned close to an open atomic transition. This nonunitary system displays survival resonances for certain driving frequencies. The survival resonances emerge as a result of the matter-wave Talbot-Lau effect, similar to the Talbot effect causing quantum resonances in the atom optics δ -kicked rotor. Since the Talbot-Lau effect occurs for incoherent waves, the survival resonances can be observed using thermal atoms. A microlensing effect can enhance the height and incisiveness of the resonances. This may find applications in precision measurements.

  6. Michael E. Lamb: Award for Distinguished Senior Career Contributions to Psychology in the Public Interest.

    PubMed

    2015-11-01

    The APA Awards for Distinguished Contributions to Psychology in the Public Interest recognize persons who have advanced psychology as a science and/or profession by a single extraordinary achievement or a lifetime of outstanding contributions in the public interest. The 2015 co-recipient of the Award for Distinguished Senior Career Contributions to Psychology in the Public Interest is Michael E. Lamb. Lamb was selected because his "work profoundly shaped the fields of developmental psychology, social welfare, child and family policy, and law." Lamb's award citation, biography, and a selected bibliography are presented here. (c) 2015 APA, all rights reserved).

  7. A colorimetric detection of acrylamide in potato chips based on nucleophile-initiated thiol-ene Michael addition.

    PubMed

    Hu, Qinqin; Fu, Yingchun; Xu, Xiahong; Qiao, Zhaohui; Wang, Ronghui; Zhang, Ying; Li, Yanbin

    2016-02-07

    Acrylamide (AA), a neurotoxin and a potential carcinogen, has been found in various thermally processed foods such as potato chips, biscuits, and coffee. Simple, cost-effective, and sensitive methods for the rapid detection of AA are needed to ensure food safety. Herein, a novel colorimetric method was proposed for the visual detection of AA based on a nucleophile-initiated thiol-ene Michael addition reaction. Gold nanoparticles (AuNPs) were aggregated by glutathione (GSH) because of a ligand-replacement, accompanied by a color change from red to purple. In the presence of AA, after the thiol-ene Michael addition reaction between GSH and AA with the catalysis of a nucleophile, the sulfhydryl group of GSH was consumed by AA, which hindered the subsequent ligand-replacement and the aggregation of AuNPs. Therefore, the concentration of AA could be determined by the visible color change caused by dispersion/aggregation of AuNPs. This new method showed high sensitivity with a linear range from 0.1 μmol L(-1) to 80 μmol L(-1) and a detection limit of 28.6 nmol L(-1), and especially revealed better selectivity than the fluorescence sensing method reported previously. Moreover, this new method was used to detect AA in potato chips with a satisfactory result in comparison with the standard methods based on chromatography, which indicated that the colorimetric method can be expanded for the rapid detection of AA in thermally processed foods.

  8. STS-92 M.S. Michael Lopez-Alegria suits up for launch

    NASA Technical Reports Server (NTRS)

    2000-01-01

    During suitup in the Operations and Checkout Building, STS-92 Mission Specialist Michael E. Lopez-Alegria smiles and clasps his hands in anticipation of a second launch attempt. He and the rest of the crew will be heading out to the Astrovan for the ride to Launch Pad 39A. During the 11-day mission to the International Space Station, four extravehicular activities (EVAs), or spacewalks, are planned for construction. The payload includes the Integrated Truss Structure Z-1 and the third Pressurized Mating Adapter. The Z-1 truss is the first of 10 that will become the backbone of the Space Station, eventually stretching the length of a football field. PMA-3 will provide a Shuttle docking port for solar array installation on the sixth Station flight and Lab installation on the seventh Station flight. Launch is scheduled for 7:17 p.m. EDT. Landing is expected Oct. 22 at 2:10 p.m. EDT.

  9. Michael Faraday on the Learning of Science and Attitudes of Mind

    NASA Astrophysics Data System (ADS)

    Crawford, Elspeth

    The paper makes use of Michael Faraday's ideas about learning, in particular his thoughts about attitudes to the unknowns of science and the development of an attitude which improves scientific decision-making. An invented scenario involving nursery school children demonstrates some attitudes displayed there. Discussion of the scenario and variation in possible outcomes suggests that Faraday's views are relevant to scientific learning in general. The main thesis of the paper is that it is central to learning in science to acknowledge that there is an inner struggle involved in facing unknowns, and that empathy with the fears and expectations of learners is an essential quality if genuinely scientific thought is to develop. It is suggested, following Faraday, that understanding our own feelings while we teach is a pre-requisite to enabling such empathy and that only then will we be in a position to evaluate accurately whether or not our pupils are thinking scientifically.

  10. New Light on the Alchemical Writings of Michael Sendivogius (1566-1636).

    PubMed

    Prinke, Rafał T

    2016-08-01

    The Polish alchemist Michael Sendivogius is best known for the influential Novum lumen chymicum, a work composed of three separate texts. Sendivogius's authorship was questioned in the mid-seventeenth century, and these reservations are still held by some modern historians. On the other hand, other early modern and modern readers not only accepted his authorship of all three texts, but also ascribed as many as eleven texts to him. This paper discusses the key works published under the anagrammatised name of Sendivogius with the aim of resolving the authorship question. Newly discovered evidence makes it possible to trace the circumstances leading to the publication of these works in much greater detail than previously, and to present new arguments affirming Sendivogius's authorship. In the Tractatus de sulphure, Sendivogius promised to write another two treatises, which readers sought to identify and (in some cases) to write themselves. This paper sets out, and rejects, the arguments for including them in the corpus of genuine Sendivogian writings.

  11. Lizards, ticks and contributions to Australian parasitology: C. Michael Bull (1947-2016).

    PubMed

    Godfrey, Stephanie S; Gardner, Michael G

    2017-12-01

    Professor C. Michael Bull was a great scientist and mentor, and an Associate Editor of this journal. While his research career spanned the fields of behavioural ecology, conservation biology and herpetology, in this article, we pay tribute to his major contribution to Australian parasitology. Mike authored more than eighty articles on host-parasite ecology, and revealed major insights into the biology and ecology of ticks from his long term study of the parapatric boundary of two tick species ( Amblyomma limbatum and Bothriocroton hydrosauri ) on the sleepy lizard ( Tiliqua rugosa ). In this article, we provide an overview of how this research journey developed to become one of the longest-running studies of lizards and their ticks, totalling 35 years of continuous surveys of ticks on lizards, and the insights and knowledge that he generated along that journey.

  12. Radiation therapy in the treatment of cervical cancer: The University of Chicago/Michael Reese Hospital experience

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rader, J.S.; Haraf, D.J.; Halpern, H.J.

    1990-07-01

    A retrospective analysis was conducted on 307 patients referred for radiation therapy at The University of Chicago and Michael Reese Hospital between 1971 and 1986. Median follow-up was 6.4 years. Treatment techniques varied during the time of the study. Actuarial disease-free survivals were 78%, 64%, 55%, 33%, 41%, and 60% for stage IB, IIA, IIB, IIIA, IIIB, and IVA, respectively. Stage, size of the cervical lesion, and hemoglobin level during treatment were prognostic factors. Treatment technique as well as time dose factors were analyzed with respect to survival, failures, and complications.

  13. SRTM Anaglyph with Landsat Overlay: Miquelon and Saint Pierre Islands

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This anaglyph satellite image shows Miquelon and Saint Pierre Islands, located south of Newfoundland, Canada. These islands are a self-governing territory of France. A 'tombolo' (sand bar) unites Grande Miquelon to the north and Petite Miquelon to the south. Saint Pierre Island, located to the lower right, includes a harbor, an airport, and a small town. Glaciers once covered these islands and the direction of glacial flow is evident in the topography as striations and shoreline trends running from the upper right to the lower left. The darkest image features are freshwater lakes that fill glacially carved depressions and saltwater lagoons that are bordered by barrier beaches. The lakes and the lagoons are fairly calm waters and reflect less sunlight than do the wave covered and sediment laden nearshore ocean currents.

    The stereoscopic effect was created by first draping a Landsat satellite image over preliminary digital elevation data from the Shuttle Radar Topography Mission (SRTM), and then generating two differing perspectives, one for each eye. When viewed through special glasses, the result is a vertically exaggerated view of the Earth's surface in its full three dimensions. Anaglyph glasses cover the left eye with a red filter and cover the right eye with a blue filter.

    Landsat has been providing visible and infrared views of the Earth since 1972. SRTM elevation data matches the 30-meter resolution of most Landsat images and will substantially help in analyses of the large and growing Landsat image archive. The Landsat 7 Thematic Mapper image used here was provided to the SRTM project by the United States Geological Survey, Earth Resources Observation Systems (EROS) DataCenter, Sioux Falls, South Dakota.

    The elevation data used in this image was acquired by SRTM aboard the Space Shuttle Endeavour, launched on February 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR

  14. Chapel of cemetery church of all saints in Sedlec - Long-term analysis of hygrothermal conditions

    NASA Astrophysics Data System (ADS)

    Pavlík, Zbyšek; Balík, Lukáš; Kudrnáčová, Lucie; Maděra, Jiří; Černý, Robert

    2017-07-01

    In this paper, long-term monitoring of hygrothermal conditions of the chapel of the cemetery church of All Saints in Sedlec, Czech Republic is presented as a practical tool for evaluation of functional problems of the researched structure. Within the performed experimental tests, interior and exterior climatic conditions were monitored over one year period. Herewith, surface temperature of the chapel wall was measured. Exterior climatic data were collected using weather station Vantage Pro2 placed in church tower. In interior, precise combined relative humidity/temperature sensors were installed. Based on the accessed hygrothermal state of the inspected chapel and identified periods of possible surface condensation, service conditions of the chapel will be optimized in order to prevent extensive damage of historically valuable finishing and furnishing materials, paintings, plasters, and architectural ornaments.

  15. Enantioselective total synthesis of (-)-strychnine using the catalytic asymmetric Michael reaction and tandem cyclization.

    PubMed

    Ohshima, Takashi; Xu, Youjun; Takita, Ryo; Shimizu, Satoshi; Zhong, Dafang; Shibasaki, Masakatsu

    2002-12-11

    The enantioselective total synthesis of (-)-strychnine was accomplished through the use of the highly practical catalytic asymmetric Michael reaction (0.1 mol % of (R)-ALB, more than kilogram scale, without chromatography, 91% yield and >99% ee) as well as a tandem cyclization that simultaneously constructed B- and D-rings (>77% yield). Moreover, newly developed reaction conditions for thionium ion cyclization, NaBH3CN reduction of the imine moiety in the presence of Lewis acid to prevent ring opening reaction, and chemoselective reduction of the thioether (desulfurization) in the presence of exocyclic olefin were pivotal to complete the synthesis. The described chemistry paves the way for the synthesis of more advanced Strychnos alkaloids.

  16. A Promiscuous De Novo Retro-Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base Intermediates.

    PubMed

    Garrabou, Xavier; Beck, Tobias; Hilvert, Donald

    2015-05-04

    Recent advances in computational design have enabled the development of primitive enzymes for a range of mechanistically distinct reactions. Here we show that the rudimentary active sites of these catalysts can give rise to useful chemical promiscuity. Specifically, RA95.5-8, designed and evolved as a retro-aldolase, also promotes asymmetric Michael additions of carbanions to unsaturated ketones with high rates and selectivities. The reactions proceed by amine catalysis, as indicated by mutagenesis and X-ray data. The inherent flexibility and tunability of this catalyst should make it a versatile platform for further optimization and/or mechanistic diversification by directed evolution. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. 'Introducing Michael Gove to Loïc Wacquant': Why Social Work Needs Critical Sociology.

    PubMed

    Michael Garrett, Paul

    2016-06-01

    In 2013, Michael Gove, then Secretary of State for Education and Health in the UK coalition government, criticised social workers for laying insufficient emphasis on the 'agency' of individuals and for being too preoccupied with social and economic inequalities. Such a perspective, which is not unique to Gove, needs to be countered by reaffirming the significance of an expansively critical sociology for social work. In this context, the thematic concerns of the French theorist, Loïc Wacquant, illuminates key aspects of social work engagement with clients which Gove and his ideological associates appear intent on ignoring. The issues raised have significant political resonances given the pending UK General Election taking place in May 2015.

  18. Correlates of Lifetime History of Purchasing Sex Services by Men in Saint Petersburg and Leningrad Oblast, Russia.

    PubMed

    Girchenko, P; Ompad, D C; Kulchynska, R; Bikmukhametov, D; Dugin, S; Gensburg, L

    2015-12-01

    Commercial sex workers (CSWs) in the Russian Federation are at high risk of HIV infection and transmission as a result of unsafe sexual and injecting behaviors. Their clients might be at increased risk of acquiring HIV; however, little is known about the population of men purchasing sex services. This study aims to investigate factors associated with a history of purchasing sex services by men in Saint Petersburg and Leningrad Oblast, Russian Federation. Data were collected as part of a cross-sectional study offering free anonymous rapid HIV testing in Saint Petersburg and Leningrad Oblast in 2014; in total, 3565 men aged 18 years and older provided information about their behaviors associated with risk of acquiring HIV during face-to-face interviews. Prevalence of CSW use in our study was 23.9%. Multivariable analyses using log-binomial regression were stratified by self-reported HIV testing during the 12 months preceding the study interview. In both strata, older age, multiple sex partners, and a history of sex with an injection drug user (IDU) were associated with an elevated prevalence ratio (PR) for history of purchasing sex services, although the strength of the association differed by strata. Among men who reported recent HIV testing, condom use (PR = 1.22, 90% confidence interval (CI) 1.0, 1.48) was associated with a history of purchasing sex services, and among men who did not report recent HIV testing, having a consistent sex partner was associated with purchasing sex services (PR = 1.23, 90% CI 1.1, 1.37). The high prevalence of CSW service use and associations found in this study raise serious concerns about potential for sexual HIV transmission and should be investigated more closely.

  19. A rapid, one-pot, microwave-influenced synthesis of spiro-2,5-diketopiperazines via a cascade Ugi/6-exo-trig aza-Michael reaction.

    PubMed

    Santra, Soumava; Andreana, Peter R

    2011-04-01

    A rapid, cascade reaction process has been developed to access biologically validated spiro-2,5-diketopiperazines. The facile and environmentally benign method capitalizes on commercially available starting reagents for a sequential Ugi/6-exo-trig aza-Michael reaction, water as a solvent, and microwave irradiation without any extraneous additives.

  20. Mechanistic Kinetic Modeling of Thiol-Michael Addition Photopolymerizations via Photocaged "Superbase" Generators: An Analytical Approach.

    PubMed

    Claudino, Mauro; Zhang, Xinpeng; Alim, Marvin D; Podgórski, Maciej; Bowman, Christopher N

    2016-11-08

    A kinetic mechanism and the accompanying mathematical framework are presented for base-mediated thiol-Michael photopolymerization kinetics involving a photobase generator. Here, model kinetic predictions demonstrate excellent agreement with a representative experimental system composed of 2-(2-nitrophenyl)propyloxycarbonyl-1,1,3,3-tetramethylguanidine (NPPOC-TMG) as a photobase generator that is used to initiate thiol-vinyl sulfone Michael addition reactions and polymerizations. Modeling equations derived from a basic mechanistic scheme indicate overall polymerization rates that follow a pseudo-first-order kinetic process in the base and coreactant concentrations, controlled by the ratio of the propagation to chain-transfer kinetic parameters ( k p / k CT ) which is dictated by the rate-limiting step and controls the time necessary to reach gelation. Gelation occurs earlier as the k p / k CT ratio reaches a critical value, wherefrom gel times become nearly independent of k p / k CT . The theoretical approach allowed determining the effect of induction time on the reaction kinetics due to initial acid-base neutralization for the photogenerated base caused by the presence of protic contaminants. Such inhibition kinetics may be challenging for reaction systems that require high curing rates but are relevant for chemical systems that need to remain kinetically dormant until activated although at the ultimate cost of lower polymerization rates. The pure step-growth character of this living polymerization and the exhibited kinetics provide unique potential for extended dark-cure reactions and uniform material properties. The general kinetic model is applicable to photobase initiators where photolysis follows a unimolecular cleavage process releasing a strong base catalyst without cogeneration of intermediate radical species.