Two African Saints in Medieval Germany.

ERIC Educational Resources Information Center

Grimm, Reinhold

1992-01-01

The origin and development of two African saints are discussed: Saint Maurice, patron saint of the eastern empire of Otto I; and Caspar, the youngest of the three Magi. Their representation in German art is described and illustrated. (Author/LB)

Saint Marina: the protectress of nephrology.

PubMed

Eftychiadis, A C; Marketos, S G

1999-01-01

Saint virgin and martyr Marina (Margarita) of Antioch in Pisidia (255-270) is recognized as the patron saint of kidney sufferers and the protectress of nephrology. Beginning in the 13th century she heals in particular patients suffering from nephropathies, pregnant women having a difficult childbirth, barren women and sickly children. She protects the patients from every side effect and complication. Saint Marina is represented in hagiography as a victor, defeating the dragon satan, holding a hammer or a cross and wearing a belt around her back in the area of kidneys. According to writers, artists and sculptors the belt is the perceivable means of Saint Marina for the miraculous recovery from and healing of kidney diseases. Therefore, kidney sufferers and pregnant women put belts upon her relics for blessing and then wore them. From the Middle Ages and Renaissance and up to the contemporary period Saint Marina (Margarita) was considered the patron saint of kidney sufferers. Justifiably she is recognized by the modern medical world as the protectress of nephrology.

50 CFR 14.18 - Marine mammals.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Marine mammals. 14.18 Section 14.18....18 Marine mammals. Any person subject to the jurisdiction of the United States who has lawfully taken a marine mammal on the high seas and who is authorized to import such marine mammal in accordance...

50 CFR 14.18 - Marine mammals.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 1 2012-10-01 2012-10-01 false Marine mammals. 14.18 Section 14.18....18 Marine mammals. Any person subject to the jurisdiction of the United States who has lawfully taken a marine mammal on the high seas and who is authorized to import such marine mammal in accordance...

50 CFR 14.18 - Marine mammals.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 1 2014-10-01 2014-10-01 false Marine mammals. 14.18 Section 14.18....18 Marine mammals. Any person subject to the jurisdiction of the United States who has lawfully taken a marine mammal on the high seas and who is authorized to import such marine mammal in accordance...

50 CFR 14.18 - Marine mammals.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 1 2011-10-01 2011-10-01 false Marine mammals. 14.18 Section 14.18....18 Marine mammals. Any person subject to the jurisdiction of the United States who has lawfully taken a marine mammal on the high seas and who is authorized to import such marine mammal in accordance...

50 CFR 14.18 - Marine mammals.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 1 2013-10-01 2013-10-01 false Marine mammals. 14.18 Section 14.18....18 Marine mammals. Any person subject to the jurisdiction of the United States who has lawfully taken a marine mammal on the high seas and who is authorized to import such marine mammal in accordance...

75 FR 38718 - Safety Zone; Sault Sainte Marie 4th of July Fireworks, St. Mary's River, Sault Sainte Marie, MI

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-06

...-AA00 Safety Zone; Sault Sainte Marie 4th of July Fireworks, St. Mary's River, Sault Sainte Marie, MI... restrict vessels from a portion of the St. Mary's River during the Sault Sainte Marie 4th of July Fireworks... the setup and launching of fireworks in conjunction with the Sault Sainte Marie 4th of July Fireworks...

Luminescence dating of Holocene dune complexes along the shore of northern France (Picardy)

NASA Astrophysics Data System (ADS)

Lauer, Tobias; Frechen, Manfred; Meurisse-Fort, Murielle; Gosselin, Guillaume; van Vliet-Lanoë, Brigitte

2010-05-01

The Holocene dune and peat complexes along the shore of northern France (Picardy) had already been studied in detail by Meurisse et al. (2005) and Meurisse-Fort (2009). Information about the palaeodevelopment of those dune fields is hence given due to existing 14C data as well as by sedimentological and morphological analyses. Due to the results from radiocarbon dating, different types of aeolian bodies could be correlated along the Picardy coastline and a regional stratigraphic sequence could be established (Meurisse-Fort, 2009). The aim of the ongoing study is to get a higher chronological resolution for the different phases of dune activity in Picardy by luminescence dating what is a powerful tool to determine the time of last sunlight exposure of grains before burial (this information yields important information about dune movement). Samples for OSL dating were taken from dune bodies located in Tardinghen, Hardelot, Saint-Frieux and Saint-Gabriel. For dating, a single aliquot regenerative dose (SAR) protocol (Murray & Wintle 2003) is applied to coarse grained quartz. First tests concerning the signal intensity, the purity of the quartz OSL signal and the bleaching properties showed that quartz OSL dating works well for the dunes of the northern France coastline. The new luminescence ages will help to better unravel the phases of sand dune activity and stabilisation mainly controlled by climate changes and human impact. References: Meurisse, M., Van Vliet-Lanoë, B., Talon, B. & Recourt, P. (2005): Complexes dunaires et tourbeux holocènes du littoral du Nord de la France. - Geoscience, 337 : 675-684. Meurisse-Fort, M. (2009): Enregistrement haute résolution des massifs dunaires ; Manche, mer du Nord et Atlantique - Le rôle des tempêtes. Thèse de Doctorat soutenue en juin 2007, Université de Lille1. Coll. Recherches - Sciences (Sciences de la Terre). EPU-Publibook (ed.), Paris, 310 pp. Murray, A.S. & Wintle, A.G. (2003): The single aliquot regenerative

MAPPING AND MONITORING OF SALT MARSH VEGETATION AND TIDAL CHANNEL NETWORK FROM HIGH RESOLUTION IMAGERY (1975-2006). EXAMPLE OF THE MONT-SAINT-MICHEL BAY (FRANCE)

NASA Astrophysics Data System (ADS)

Puissant, A. P.; Kellerer, D.; Gluard, L.; Levoy, F.

2009-12-01

Coastal landscapes are severely affected by environmental and social pressures. Their long term development is controlled by both physical and anthropogenic factors, which spatial dynamics and interactions may be analysed by Earth Observation data. The Mont-Saint-Michel Bay (Normandy, France) is one of the European coastal systems with a very high tidal range (approximately 15m during spring tides) because of its geological, geomorphological and hydrodynamical contexts at the estuary of the Couesnon, Sée and Sélune rivers. It is also an important touristic place with the location of the Mont-Saint-Michel Abbey, and an invaluable ecosystem of wetlands forming a transition between the sea and the land. Since 2006, engineering works are performed with the objective of restoring the maritime character of the Bay. These works will lead to many changes in the spatial dynamics of the Bay which can be monitored with two indicators: the sediment budget and the wetland vegetation surfaces. In this context, the aim of this paper is to map and monitor the tidal channel network and the extension of the salt marsh vegetation formation in the tidal zone of the Mont-Saint-Michel Bay by using satellite images. The spatial correlation between the network location of the three main rivers and the development of salt marsh is analysed with multitemporal medium (60m) to high spatial resolution (from 10 to 30 m) satellite images over the period 1975-2006. The method uses a classical supervised algorithm based on a maximum likelihood classification of eleven satellites images. The salt-marsh surfaces and the tidal channel network are then integrated in a GIS. Results of extraction are assessed by qualitative (visual interpretation) and quantitative indicators (confusion matrix). The multi-temporal analysis between 1975 and 2006 highlights that in 1975 when the study area is 26000 ha, salt marshes cover 16% (3000ha), the sandflat (slikke) and the water represent respectively 59% and 25

Saint: a lightweight integration environment for model annotation.

PubMed

Lister, Allyson L; Pocock, Matthew; Taschuk, Morgan; Wipat, Anil

2009-11-15

Saint is a web application which provides a lightweight annotation integration environment for quantitative biological models. The system enables modellers to rapidly mark up models with biological information derived from a range of data sources. Saint is freely available for use on the web at http://www.cisban.ac.uk/saint. The web application is implemented in Google Web Toolkit and Tomcat, with all major browsers supported. The Java source code is freely available for download at http://saint-annotate.sourceforge.net. The Saint web server requires an installation of libSBML and has been tested on Linux (32-bit Ubuntu 8.10 and 9.04).

Public Notice: Saint-Gobain Abrasives, Inc. and Saint-Gobain Ceramics & Plastics, Inc., CWA-01-2016-0057

EPA Pesticide Factsheets

Notice of Proposed Assessment of Class II Civil Penalty and Notice of Opportunity for Hearing under Sections 309(g) and 311(b)(6) of the Clean Water Act for Saint-Gobain Abrasives, Inc. and Saint-Gobain Ceramics & Plastics, Inc., CWA-01-2016-0057

Minneapolis-Saint Paul air cargo study

DOT National Transportation Integrated Search

2001-12-01

The Minneapolis-Saint Paul Task Force commissioned this study. It was established to address the apparent decline in air cargo through Minneapolis-Saint Paul airport in recent years. Distribution services, especially international air cargo, are stra...

Marcel Breuer at Saint John's

ERIC Educational Resources Information Center

Carlson, Scott

2008-01-01

A visitor to Saint John's University and Saint John's Abbey, in north-central Minnesota, sees something of Gothic heritage while standing in front of the abbey church, designed and built around 1960. The church's 112-foot campanile--a trapezoidal slab made of 2,500 tons of steel and concrete--stands boldly in front of a huge concrete honeycomb…

Restored Roots: "Muntu" as a Healing Agent in "Pelo bueno, Pelo malo" by Carmen Montañez

ERIC Educational Resources Information Center

Edison, Thomas Wayne

2017-01-01

Carmen Montañez's novel "Pelo bueno, pelo malo" acknowledges the struggle that some Caribbean individuals face in accepting their blackness. The novel integrates the union of ancestors with the living, thus reflecting the Bantu concept known as "Muntu". This Puerto Rican novel presents a deep social problem of internalized…

A Mosquito Survey of the Twin-Island Caribbean Nation of Saint Kitts and Nevis, 2010.

PubMed

Mohammed, Hamish; Evanson, Jessica; Revan, Floyd; Lee, Elise; Krecek, Rosina C; Smith, Joshua

2015-12-01

Adult mosquito surveys of Saint Kitts and Nevis (SKN) were performed in the dry season (March 16-23, 2010) in Saint Kitts, and the rainy season (October 18-25, 2010) in SKN. Biogents (BG) Sentinel Traps were set with CO₂and BG Lure in urban, rural, mangrove, and dry forest habitats. Mosquitoes were identified to species, and reverse transcription-polymerase chain reaction was performed on potential vector species for dengue virus (DENV), chikungunya virus (CHIKV), and West Nile virus (WNV). The most abundant species during both seasons in St. Kitts were Culex quinquefasciatus, Aedes taeniorhynchus, and Aedes aegypti. There were 3 new records for Saint Kitts: Aedes tortilis, Anopheles albimanus, and Culex nigripalpus. Traps were also set in Nevis. No mosquito pool tested positive for DENV, CHIKV, or WNV.

15 CFR 14.18 - Taxpayer identification number.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Taxpayer identification number. 14.18... COMMERCIAL ORGANIZATIONS Pre-Award Requirements § 14.18 Taxpayer identification number. In accordance with... identifying number will be required from applicants for grants and cooperative agreements funded by the DoC...

18 CFR 1b.14 - Subpoenas.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Subpoenas. 1b.14 Section 1b.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.14 Subpoenas. (a) Service of a subpoena...

18 CFR 1b.14 - Subpoenas.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Subpoenas. 1b.14 Section 1b.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.14 Subpoenas. (a) Service of a subpoena...

18 CFR 1b.14 - Subpoenas.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Subpoenas. 1b.14 Section 1b.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.14 Subpoenas. (a) Service of a subpoena...

18 CFR 1b.14 - Subpoenas.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Subpoenas. 1b.14 Section 1b.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.14 Subpoenas. (a) Service of a subpoena...

[Louis XIV's Ginseng: Shaping of Knowledge on an Herbal Medicine in the Late 17th and the Early 18th Century France].

PubMed

Lee, Hye-Min

2016-04-01

This article aims to investigate the shaping of knowledge and discourse on ginseng, especially among physicians and botanists, since its introduction to France from the 17th century until the early 18th century. In France, knowledge on herbal medicine, including that of ginseng, was shaped under the influence of the modern state's policy and institution: mercantilism and the Académie royale des sciences. The knowledge of herbal medicine developed as an important part of the mercantilist policy supported systematically by the Académie. The East Asian ginseng, renowned as a panacea, was first introduced into France in the 17th century, initially in a roundabout way through transportation and English and Dutch publications of travel tales from various foreign countries. The publication activity was mainly conducted by Thévenot company with the intention to meet the needs of French mercantilism promoted by Colbert. It also implied interests on medicine in order to bolster the people's health. The Thévenot company's activity thus offered vital information on plants and herbs abroad, one of which was ginseng. Furthermore, with Louis XIV's dispatching of the Jesuit missionaries to East Asia, the Frenchmen were able to directly gather information on ginseng. These information became a basis for research of the Académie. In the Académie, founded in 1666 by Colbert, the king's physicians and botanists systematically and collectively studied on exotic plants and medical herbs including ginseng. They were also key figures of the Jardin du Roi. These institutions bore a striking contrast to the faculty of medicine at the University of Paris which has been a center of the traditional Galenic medicine. The research of the Académie on ginseng was greatly advanced, owing much to the reports and samples sent from China and Canada by Jartoux, Sarrazin, and Lapitau. From the early 18th century, the conservative attitude of the University of Paris, which was a stronghold of

Giant worms chez moi! Hammerhead flatworms (Platyhelminthes, Geoplanidae, Bipalium spp., Diversibipalium spp.) in metropolitan France and overseas French territories

PubMed Central

Winsor, Leigh; Gey, Delphine; Gros, Pierre; Thévenot, Jessica

2018-01-01

Background Species of the genera Bipalium and Diversibipalium, or bipaliines, are giants among land planarians (family Geoplanidae), reaching length of 1 m; they are also easily distinguished from other land flatworms by the characteristic hammer shape of their head. Bipaliines, which have their origin in warm parts of Asia, are invasive species, now widespread worldwide. However, the scientific literature is very scarce about the widespread repartition of these species, and their invasion in European countries has not been studied. Methods In this paper, on the basis of a four year survey based on citizen science, which yielded observations from 1999 to 2017 and a total of 111 records, we provide information about the five species present in Metropolitan France and French overseas territories. We also investigated the molecular variability of cytochrome-oxidase 1 (COI) sequences of specimens. Results Three species are reported from Metropolitan France: Bipalium kewense, Diversibipalium multilineatum, and an unnamed Diversibipalium ‘black’ species. We also report the presence of B. kewense from overseas territories, such as French Polynesia (Oceania), French Guiana (South America), the Caribbean French islands of Martinique, Guadeloupe, Saint Martin and Saint Barthélemy, and Montserrat (Central America), and La Réunion island (off South-East Africa). For B. vagum, observations include French Guiana, Guadeloupe, Martinique, Saint Barthélemy, Saint Martin, Montserrat, La Réunion, and Florida (USA). A probable new species, Diversibipalium sp. ‘blue,’ is reported from Mayotte Island (off South–East Africa). B. kewense, B. vagum and D. multilineatum each showed 0% variability in their COI sequences, whatever their origin, suggesting that the specimens are clonal, and that sexual reproduction is probably absent. COI barcoding was efficient in identifying species, with differences over 10% between species; this suggests that barcoding can be used in the

A "Sacra Rappresentazione" of Saint Apollonia's Martyrdom.

PubMed

Eramo, Stefano; Natali, Alessio; Bravi, Monia; Cella, Diana; Milia, Egle

The literary sources of Saint Apollonia's martyrdom and the evolution of Medieval and Renaissance religious drama are presented along with the compendium of a "Sacra Rappresentazione" from Italian Renaissance regarding Saint Apollonia's Martyrdom. Copyright American Academy of the History of Dentistry.

14 CFR 61.18 - Security disqualification.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Security disqualification. 61.18 Section 61...) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS General § 61.18 Security... issued under this part when the Transportation Security Administration (TSA) has notified the FAA in...

14 CFR 61.18 - Security disqualification.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Security disqualification. 61.18 Section 61...) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS General § 61.18 Security... issued under this part when the Transportation Security Administration (TSA) has notified the FAA in...

14 CFR 61.18 - Security disqualification.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Security disqualification. 61.18 Section 61...) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS General § 61.18 Security... issued under this part when the Transportation Security Administration (TSA) has notified the FAA in...

René Goupil: patron saint of anesthetists.

PubMed

Quintal, J

1995-06-01

René Goupil, the patron saint of anesthetists, is addressed mainly as a 17th century French surgeon who practiced his art in North America. He is also presented as a Jesuit martyr and saint. The article freely borrows from past writings of Jesuits on René Goupil.

SAINT: A combined simulation language for modeling man-machine systems

NASA Technical Reports Server (NTRS)

Seifert, D. J.

1979-01-01

SAINT (Systems Analysis of Integrated Networks of Tasks) is a network modeling and simulation technique for design and analysis of complex man machine systems. SAINT provides the conceptual framework for representing systems that consist of discrete task elements, continuous state variables, and interactions between them. It also provides a mechanism for combining human performance models and dynamic system behaviors in a single modeling structure. The SAINT technique is described and applications of the SAINT are discussed.

27 CFR 18.14 - Emergency variations from requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Emergency variations from requirements. 18.14 Section 18.14 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Administrative...

27 CFR 18.14 - Emergency variations from requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Emergency variations from requirements. 18.14 Section 18.14 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Administrative...

27 CFR 18.14 - Emergency variations from requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Emergency variations from requirements. 18.14 Section 18.14 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Administrative...

27 CFR 18.14 - Emergency variations from requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Emergency variations from requirements. 18.14 Section 18.14 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Administrative...

27 CFR 18.14 - Emergency variations from requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Emergency variations from requirements. 18.14 Section 18.14 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL PRODUCTION OF VOLATILE FRUIT-FLAVOR CONCENTRATE Administrative...

Compressive strength evolution of thermally-stressed Saint Maximin limestone.

NASA Astrophysics Data System (ADS)

Farquharson, J.; Griffiths, L.; Baud, P.; Wadsworth, F. B.; Heap, M. J.

2017-12-01

The Saint Maximin quarry (Oise, France) opened in the early 1600s, and its limestone has been used extensively as masonry stone, particularly during the classical era of Parisian architecture from the 17th century onwards. Its widespread use has been due to a combination of its regional availability, its high workability, and its aesthetic appeal. Notable buildings completed using this material include sections of the Place de la Concorde and the Louvre in Paris. More recently, however, it has seen increasing use in the construction of large private residences throughout the United States as well as extensions to private institutions such as Stanford University. For any large building, fire hazard can be a substantial concern, especially in tectonically active areas where catastrophic fires may arise following large-magnitude earthquakes. Typically, house fires burn at temperatures of around 600 °C ( 1000 F). Given the ubiquity of this geomaterial as a building stone, it is important to ascertain the influence of heating on the strength of Saint Maximin limestone (SML), and in turn the structural stability of the buildings it is used in. We performed a series of compressive tests and permeability measurements on samples of SML to determine its strength evolution in response to heating to incrementally higher temperatures. We observe that the uniaxial compressive strength of SML decreases from >12 MPa at room temperature to <7 MPa at 600 °C. The rate of strength reduction increases at elevated temperature (>400 °C). We anticipate that this substantial weakening is in part a result of thermal microcracking, whereby changes in temperature induce thermal stresses due to a mismatch in thermal expansion between the constituent grains. This mechanism is compounded by the volumetric increase of quartz through its alpha - beta transition at 573 °C, and by the thermal decomposition of calcite. To track the formation of thermal microcracks, we monitor acoustic emissions

Prevalence of ciguatoxins in lionfish (Pterois spp.) from Guadeloupe, Saint Martin, and Saint Barthélmy Islands (Caribbean).

PubMed

Soliño, Lucía; Widgy, Saha; Pautonnier, Anthony; Turquet, Jean; Loeffler, Christopher R; Flores Quintana, Harold A; Diogène, Jorge

2015-08-01

Lionfish (Pterois spp.) are invasive species that have recently spread throughout the Caribbean. Lionfish are available for purchase in local markets for human consumption in several islands of the region. We examined the prevalence of ciguatoxins (CTXs) in lionfish from the French Antilles, a ciguatera-endemic region. The neuroblastoma-2a (N2a) cell assay was used to assess composite cytotoxicity in 120 fish samples collected from the surrounding waters of Guadeloupe (n = 60), Saint Barthélemy Islands (n = 55) and Saint Martin (n = 5). Twenty-seven of these samples exhibited CTX-like activity by the N2a assay. Ciguatoxin (CTX) was confirmed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) in multiple samples that presented highest composite toxicity levels by N2a. Those fish found to contain CTXs were all from Saint Barthélemy. Lionfish from Guadeloupe and Saint Martin did not exhibit toxin activity, although the sample size from Saint Martin was insufficient to draw any conclusions as to the incidence of CTXs. In this study, we provide information about the potential hazard of ciguatera associated with the consumption of lionfish from known endemic areas. We also demonstrate the utility of the cell-based assay combined with LC-MS/MS to assess activity and to provide structural confirmation of CTXs respectively. Copyright © 2015 Elsevier Ltd. All rights reserved.

Evidence for tuberculosis in 18th/19th century slaves in Anse Sainte-Marguerite (Guadeloupe - French Western Indies).

PubMed

Lösch, Sandra; Kim, Mi-Ra; Dutour, Olivier; Courtaud, Patrice; Maixner, Frank; Romon, Thomas; Sola, Christophe; Zink, Albert

2015-06-01

During the American colonization in the 18th and 19th century, Africans were captured and shipped to America. Harsh living and working conditions often led to chronic diseases and high mortality rates. Slaves in the Caribbean were forced to work mainly on sugar plantations. They were buried in cemeteries like Anse Sainte-Marguerite on the isle of Grande-Terre (Guadeloupe) which was examined by archaeologists and physical anthropologists. Morphological studies on osseous remains of 148 individuals revealed 15 cases with signs for bone tuberculosis and a high frequency of periosteal reactions which indicates early stages of the disease. 11 bone samples from these cemeteries were analysed for ancient DNA. The samples were extracted with established procedures and examined for the cytoplasmic multicopy β-actin gene and Mycobacterium tuberculosis complex DNA (IS 6110) by PCR. An amplification product for M. tuberculosis with the size of 123 bp was obtained. Sequencing confirmed the result. This study shows evidence of M. tuberculosis complex DNA in a Caribbean slave population. Copyright © 2015 Elsevier Ltd. All rights reserved.

Visible saints: social cynosures and dysphoria in the Mediterranean tradition.

PubMed

Gaines, A D; Farmer, P E

1986-12-01

"Visible saints" are individuals in the Mediterranean culture area who lead lives of heroic, exemplary and public suffering. This paper offers an analysis of visible saints as social cynosures as a means of exploring critical cultural psychiatric issues. We examine the changing nature of saintly suffering in the culture area and look at the media through which familiarity with the saints and their passions is developed and maintained. A detailed clinical case study is presented of "Madame Lorca," identified by her peers as a "saint." We focus on a particular illness episode which proved to be an amplification of symptoms of long standing. Psychiatric diagnostic instruments were administered and indicated the presence of severe clinical depression. However, our research suggests that Mme. Lorca's symptomatology reflects culturally specific methods of coping with dysphoric affects and chronic illness. The paper concludes with an exploration of the nature of personal illness as it relates to a wider cultural system of meaning. The findings demonstrate that the visible saint and her symptomatology are part of a cultural system which generates, promotes, patterns and frames the experience of dysphoric affect in a cultural complex quite distinct from that of clinical depression.

The Saint Louis River Idea-Slam crowd sourcing good ideas ...

EPA Pesticide Factsheets

As part of the 2017 Saint Louis River Summit, we propose hosting an “Idea-Slam” using software originally developed by the U.S. Consumer Financial Protection Bureau. Idea-box is an open source online app/website used to collect and surface ideas from members of an organization, or the public in general. Using the app, users login, view a request or challenge for new ideas, can submit their own ideas and/or view, comment and vote on other previously submitted ideas. Initially we will start with three idea request or “challenges” as listed below. The first will be run prior to the Summit to help generate additional challenges that might be added for the summit depending on the results. Initial Idea Challenges:1. (Prior to summit) If you could ask a large group of Saint Louis River focused scientist, stakeholders, managers, politicians and the public a question about the SLR, what would you ask?2. How might we better engage students and educators with the Saint Louis River?3. How might we employ citizen science for the Saint Louis River?The Idea-box app will be available for users two weeks before the Saint Louis Summit. We will e-mail previous summit participants and others an invitation to participate in “The Saint Louis River Idea-Slam” with clear instruction on how to proceed. During the morning of the first day at the Saint Louis Summit we will make a brief announcement about the Idea-Slam (< 2min.), and invite everyone to participate.

Dietary habits in New France during the 17th and 18th centuries: An isotopic perspective.

PubMed

Vigeant, J; Ribot, I; Hélie, J-F

2017-03-01

Little attention has been given, so far, to the early colonial diet in New France from an isotopic perspective. Historical records that compare France to New France suggest a shift toward a more diverse diet, including a higher protein intake due to an improvement in living conditions in the New World, despite the retention of ancestral dietary habits. This hypothesis will be explored here. Stable carbon (organic and mineral) and nitrogen isotopes were measured on 43 individuals from Notre Dame cemetery (first Catholic parish church cemetery in Montreal, 1683-1803) as well as 13 French compatriots from La Rochelle, France (Protestant Hospital Cemetery, 1765-1792). Intragroup variation (age at death, sex, and/or burial location) was investigated and compared to compiled data from various northeastern North American sites (N = 99). The Notre Dame sample means are as follows: -19.6‰ versus VPDB for δ 13 C collagen , -12.22‰ versus VPDB for δ 13 C carbonate , and 11.5‰ versus AIR for δ 15 N. They are significantly lower than both La Rochelle (-18.4‰, -11.67‰, and 12.7‰, respectively, p ≤ .005) and the northeastern North American groups used for this comparison (p = .000). The isotopic values obtained from Notre Dame cemetery suggest that the diet was mainly based on C 3 resources with limited C 4 resources. Although different from all comparable contemporary sites, colonial Montreal's diet remains most similar to La Rochelle, France. This study agrees with historians who have suggested that French dietary traditions seem to have been retained among the early colonial inhabitants of Montreal. © 2016 Wiley Periodicals, Inc.

Composition of Fish Communities in a European Macrotidal Salt Marsh (the Mont Saint-Michel Bay, France)

NASA Astrophysics Data System (ADS)

Laffaille, P.; Feunteun, E.; Lefeuvre, J.-C.

2000-10-01

At least 100 fish species are known to be present in the intertidal areas (estuaries, mudflats and salt marshes) of Mont Saint-Michel Bay. These and other comparable shallow marine coastal waters, such as estuaries and lagoons, play a nursery role for many fish species. However, in Europe little attention has been paid to the value of tidal salt marshes for fishes. Between March 1996 and April 1999, 120 tides were sampled in a tidal creek. A total of 31 species were caught. This community was largely dominated by mullets ( Liza ramada represent 87% of the total biomass) and sand gobies ( Pomatoschistus minutus and P. lozanoi represent 82% of the total numbers). These species and also Gasterosteus aculeatus , Syngnathus rostellatus, Dicentrarchus labrax, Mugil spp., Liza aurata and Sprattus sprattus were the most frequent species (>50% of monthly frequency of occurrence). In Europe, salt marshes and their creeks are flooded only during high spring tides. So, fishes only invade this environment during short immersion periods, and no species can be considered as marsh resident. But, the salt marsh was colonized by fish every time the tide reached the creek, and during the short time of flood, dominant fishes fed actively and exploited the high productivity. Nevertheless, this study shows that there is little interannual variation in the fish community and there are three ' seasons ' in the fish fauna of the marsh. Marine straggler and marine estuarine dependent species colonize marshes between spring (recruitment period in the bay) and autumn before returning into deeper adjacent waters. Estuarine fishes are present all year round with maximum abundances in the end of summer. The presence of fishes confirms that this kind of wetland plays an important trophic and nursery role for these species. Differences in densities and stages distribution of these species into Mont Saint-Michel systems (tidal mudflats, estuaries and tidal salt marshes) can reduce the trophic

18 CFR 16.14 - Departmental recommendation for takeover.

Code of Federal Regulations, 2013 CFR

2013-04-01

... hydroelectric power project with a license that is subject to sections 14 and 15 of the Federal Power Act. The... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Departmental recommendation for takeover. 16.14 Section 16.14 Conservation of Power and Water Resources FEDERAL ENERGY...

18 CFR 16.14 - Departmental recommendation for takeover.

Code of Federal Regulations, 2014 CFR

2014-04-01

... hydroelectric power project with a license that is subject to sections 14 and 15 of the Federal Power Act. The... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Departmental recommendation for takeover. 16.14 Section 16.14 Conservation of Power and Water Resources FEDERAL ENERGY...

A 2D numerical approach to predict sedimentary deposits of submarine gravity flows based on a Saint-Venant model with density variation effects. Example of Annot Basin (SE, France)

NASA Astrophysics Data System (ADS)

Le Solleuz, A.; Golfier, F.; Verdon, N.

2010-12-01

Submarine gravity flows, so called hyperpycnal currents, are very fast and can be induced by a major river flood or submarine slope instability. Sedimentary deposits, due to the stacking of these events (2 or 3 per year) during millions years can constitute a very good reservoir. However, predicting the evolution of such a sedimentary filling over geological time scales is a tremendous task. Especially, the ability to predict the starting of avalanches and the knowledge of mechanisms which drive erosion and sedimentary deposits are very poor. We focus in this study on the Annot sandstones system in the Alps (SE of France) which developed a very large tertiary deep sea fan well exposed and well studied in a sedimentary point of view (tectonics, sources, facies distribution, duration, etc.). We propose here to simulate the spatial distribution of these high-concentrated submarine gravity flows taking into account density variations of the sediment-water mixture. The main difficulty of our approach consists in simulating thousands events in a reasonable computational time. The ultimate goal is to apply this numerical model to the configuration of Annot Basin and to compare our results to the different existing deposits. To understand the physical processes that drive these hyperpycnal flows (high concentrated turbidites), many researchers focused on an accurate description of the phenomenon, for example by solving the 3D Navier-Stokes equations coupled with a mass transport equation. But, if such approaches are well-suited for the description of a single event, they are too computationally expensive to predict the sedimentary deposit over millions of years, i.e. over millions of events. We propose here an adapted version of the multilayer Saint-Venant model. It allows obtaining results with a low computational time (i.e. well-suited for millions of flows). Given the difference of sediment concentration between the head and the tail of a turbidite, we have derived a

France. Country profile. [France's economy adjusts to a declining birth rate].

PubMed

Inserra, P

1984-09-01

This discussion of France focuses on regions and cities, age distribution, households and families, housing, labor force, consumption, education, and communications. France counted 54,334,871 citizens as of March 4, 1982. There were 250,000 more people than in 1975, yielding a 7-year growth rate of 3.3%. If present trends continue, there will be 56 million French by the end of the 1980s. Since 1975 when the last census was conducted, cities of more than 200,000 lost an average of 5% of their residents. For the 1st time in more than a century, urban areas of 20,000 or more did not gain population but merely held their own. France continues to experience the effects of the large-scale decimation of its male population during the 2 world wars. The World war i loss showed up March 1982 as a relatively smaller 60-74 group. Conversely the population aged 75 and over is growing, both in absolute numbers and as a percent of the population. There were 3.6 million aged 75 and over (6.6% of the population) in 1982 compared with 3 million (5.6%) in 1975. The 19 and under age group declined between 1975-85, from 31% (16.2 million) to 29% (15.6 million). The 20-59 year old group constitutes the largest segment of the population--about double the group aged 19 and under--and its growing. This group was 50% of the population in 1973 and 53% in 1982. The infant mortality rate has declined steadily in France, from 18.2 deaths/1000 births in 1970 to 13.6 in 1975 and 9.5 at present. The total fertility rate has continued to decline: 1.8 children/woman in the 1982 census a rate less than the number needed to replace the present French population. Between 1975-82 households grew 10.4% to a total of 19.6 million. The growth in the number of households is attributed to the increase in divorce and the tendency for French children to leave the parental home at an earlier age. France has nearly 23 million dwelling places. More than half of householders own their own homes. New housing starts

14 CFR 1300.18 - Issuance of the guarantee.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Issuance of the guarantee. 1300.18 Section 1300.18 Aeronautics and Space AIR TRANSPORTATION SYSTEM STABILIZATION OFFICE OF MANAGEMENT AND BUDGET AVIATION DISASTER RELIEF-AIR CARRIER GUARANTEE LOAN PROGRAM Minimum Requirements and Application Procedures...

18 CFR 341.14 - Special permission.

Code of Federal Regulations, 2010 CFR

2010-04-01

... requested waiver. If the application requests permission to make changes in joint tariffs, it must state... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Special permission. 341... COMPANIES SUBJECT TO SECTION 6 OF THE INTERSTATE COMMERCE ACT § 341.14 Special permission. (a) Procedure...

18 CFR 16.14 - Departmental recommendation for takeover.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Departmental recommendation for takeover. 16.14 Section 16.14 Conservation of Power and Water Resources FEDERAL ENERGY... department or agency may file a recommendation that the United States exercise its right to take over a...

77 FR 57996 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-19

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... directive (AD): 2012-18-08 EUROCOPTER FRANCE: Amendment 39-17184; Docket No. FAA- 2011-1408; Directorate...

50 CFR 18.14 - Marine mammals taken before the Act.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Marine mammals taken before the Act. 18.14... WILDLIFE AND PLANTS (CONTINUED) MARINE MAMMALS Prohibitions § 18.14 Marine mammals taken before the Act. (a) Section 102(e) of the Act provides in effect that the Act shall not apply to any marine mammal taken prior...

50 CFR 18.14 - Marine mammals taken before the Act.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 8 2011-10-01 2011-10-01 false Marine mammals taken before the Act. 18.14... WILDLIFE AND PLANTS (CONTINUED) MARINE MAMMALS Prohibitions § 18.14 Marine mammals taken before the Act. (a) Section 102(e) of the Act provides in effect that the Act shall not apply to any marine mammal taken prior...

50 CFR 18.14 - Marine mammals taken before the Act.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 9 2014-10-01 2014-10-01 false Marine mammals taken before the Act. 18.14... WILDLIFE AND PLANTS (CONTINUED) MARINE MAMMALS Prohibitions § 18.14 Marine mammals taken before the Act. (a) Section 102(e) of the Act provides in effect that the Act shall not apply to any marine mammal taken prior...

50 CFR 18.14 - Marine mammals taken before the Act.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 9 2012-10-01 2012-10-01 false Marine mammals taken before the Act. 18.14... WILDLIFE AND PLANTS (CONTINUED) MARINE MAMMALS Prohibitions § 18.14 Marine mammals taken before the Act. (a) Section 102(e) of the Act provides in effect that the Act shall not apply to any marine mammal taken prior...

50 CFR 18.14 - Marine mammals taken before the Act.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 9 2013-10-01 2013-10-01 false Marine mammals taken before the Act. 18.14... WILDLIFE AND PLANTS (CONTINUED) MARINE MAMMALS Prohibitions § 18.14 Marine mammals taken before the Act. (a) Section 102(e) of the Act provides in effect that the Act shall not apply to any marine mammal taken prior...

3-D perspective of Saint Pierre and Miquelon Islands

NASA Technical Reports Server (NTRS)

2000-01-01

This image shows two islands, Miquelon and Saint Pierre, located south of Newfoundland, Canada. These islands, along with five smaller islands, are a self-governing territory of France. A thin barrier beach divides Miquelon, with Grande Miquelon to the north and Petite Miquelon to the south. Saint Pierre Island is located to the lower right. With the islands' location in the north Atlantic Ocean and their deep water ports, fishing is the major part of the economy. The maximum elevation of the island is 240 meters (787 feet). The land mass of the islands is about 242 square kilometers, or 1.5 times the size of Washington DC.

This image shows how data collected by the Shuttle Radar Topography Mission (SRTM) can be used to enhance other satellite images. Color and natural shading are provided by a Landsat 7 image acquired on September 1, 1999. Terrain perspective and shading were derived from SRTM elevation data acquired on February 12, 2000. Topography is exaggerated by about six times vertically. The United States Geological Survey's Earth Resources Observations Systems (EROS) DataCenter, Sioux Falls, South Dakota, provided the Landsat data.

Elevation data used in this image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on February 11,2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between the National Aeronautics and Space Administration (NASA), the National Imagery and Mapping Agency (NIMA) of the U.S. Department of Defense (DoD), and the German and Italian space agencies

Paediatric clinical research from the perspective of hospital pharmacists from France and Canada.

PubMed

Guérin, Aurélie; Tanguay, Cynthia; Lebel, Denis; Prot-Labarthe, Sonia; Bourdon, Olivier; Bussières, Jean-François

2014-12-01

To compare pharmacy support for paediatric research services in France and Canada and to describe the perception of pharmacists and rank the paediatric clinical research issues. This was a cross-sectional descriptive study. All paediatric hospitals from Canada and the main hospitals from France were contacted. A survey was conducted from May-September 2012. Descriptive statistics were performed. Results from 11 paediatric hospitals in Canada (11/12, 92%) and 11 (11/18, 61%) in France were obtained. There was a similar number of ongoing paediatric clinical trials per hospital in France versus Canada (38 (10-81) versus 20 (4-178)). A lower number of pharmacists per hospital was observed in France (17 (11.5-35) versus 45 (18.9-76.8)), but a similar number of pharmacists were assigned to clinical trials (1.5 (1-3) versus 1.9 (0.2-17.4)). Institutional protocols represented the majority of paediatric clinical trials in France (61% (14-100) versus 25% (0-100)). Similar pharmacy support services were offered, but the majority of French respondents also offered help for institutional protocol development (91 versus 50% P = 0.063). The main issues associated with paediatric clinical research were absence of financial interest from the pharmaceutical industry, prohibitive cost versus profit ratio, small patient cohorts and the non-availability of the appropriate drug formulations. Difficulties related to pharmaceutical compounding were identified as the main hindrance to paediatric clinical research; particular attention should be paid to these details when setting up a paediatric trial. © 2014 Royal Pharmaceutical Society.

Temporal Trends in Transcatheter Aortic Valve Replacement in France: FRANCE 2 to FRANCE TAVI.

PubMed

Auffret, Vincent; Lefevre, Thierry; Van Belle, Eric; Eltchaninoff, Hélène; Iung, Bernard; Koning, René; Motreff, Pascal; Leprince, Pascal; Verhoye, Jean Philippe; Manigold, Thibaut; Souteyrand, Geraud; Boulmier, Dominique; Joly, Patrick; Pinaud, Frédéric; Himbert, Dominique; Collet, Jean Philippe; Rioufol, Gilles; Ghostine, Said; Bar, Olivier; Dibie, Alain; Champagnac, Didier; Leroux, Lionel; Collet, Frédéric; Teiger, Emmanuel; Darremont, Olivier; Folliguet, Thierry; Leclercq, Florence; Lhermusier, Thibault; Olhmann, Patrick; Huret, Bruno; Lorgis, Luc; Drogoul, Laurent; Bertrand, Bernard; Spaulding, Christian; Quilliet, Laurent; Cuisset, Thomas; Delomez, Maxence; Beygui, Farzin; Claudel, Jean-Philippe; Hepp, Alain; Jegou, Arnaud; Gommeaux, Antoine; Mirode, Anfani; Christiaens, Luc; Christophe, Charles; Cassat, Claude; Metz, Damien; Mangin, Lionel; Isaaz, Karl; Jacquemin, Laurent; Guyon, Philippe; Pouillot, Christophe; Makowski, Serge; Bataille, Vincent; Rodés-Cabau, Josep; Gilard, Martine; Le Breton, Hervé

2017-07-04

Transcatheter aortic valve replacement (TAVR) is standard therapy for patients with severe aortic stenosis who are at high surgical risk. However, national data regarding procedural characteristics and clinical outcomes over time are limited. The aim of this study was to assess nationwide performance trends and clinical outcomes of TAVR during a 6-year period. TAVRs performed in 48 centers across France between January 2013 and December 2015 were prospectively included in the FRANCE TAVI (French Transcatheter Aortic Valve Implantation) registry. Findings were further compared with those reported from the FRANCE 2 (French Aortic National CoreValve and Edwards 2) registry, which captured all TAVRs performed from January 2010 to January 2012 across 34 centers. A total of 12,804 patients from FRANCE TAVI and 4,165 patients from FRANCE 2 were included in this analysis. The median age of patients was 84.6 years, and 49.7% were men. FRANCE TAVI participants were older but at lower surgical risk (median logistic European System for Cardiac Operative Risk Evaluation [EuroSCORE]: 15.0% vs. 18.4%; p < 0.001). More than 80% of patients in FRANCE TAVI underwent transfemoral TAVR. Transesophageal echocardiography guidance decreased from 60.7% to 32.3% of cases, whereas more recent procedures were increasingly performed in hybrid operating rooms (15.8% vs. 35.7%). Rates of Valve Academic Research Consortium-defined device success increased from 95.3% in FRANCE 2 to 96.8% in FRANCE TAVI (p < 0.001). In-hospital and 30-day mortality rates were 4.4% and 5.4%, respectively, in FRANCE TAVI compared with 8.2% and 10.1%, respectively, in FRANCE 2 (p < 0.001 for both). Stroke and potentially life-threatening complications, such as annulus rupture or aortic dissection, remained stable over time, whereas rates of cardiac tamponade and pacemaker implantation significantly increased. The FRANCE TAVI registry provided reassuring data regarding trends in TAVR performance in an all

18 CFR 16.18 - Annual licenses for projects subject to sections 14 and 15 of the Federal Power Act.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Annual licenses for projects subject to sections 14 and 15 of the Federal Power Act. 16.18 Section 16.18 Conservation of Power... Projects Subject to Sections 14 and 15 of the Federal Power Act § 16.18 Annual licenses for projects...

18 CFR 16.18 - Annual licenses for projects subject to sections 14 and 15 of the Federal Power Act.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Annual licenses for projects subject to sections 14 and 15 of the Federal Power Act. 16.18 Section 16.18 Conservation of Power... Projects Subject to Sections 14 and 15 of the Federal Power Act § 16.18 Annual licenses for projects...

18 CFR 16.18 - Annual licenses for projects subject to sections 14 and 15 of the Federal Power Act.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Annual licenses for projects subject to sections 14 and 15 of the Federal Power Act. 16.18 Section 16.18 Conservation of Power... Projects Subject to Sections 14 and 15 of the Federal Power Act § 16.18 Annual licenses for projects...

18 CFR 16.18 - Annual licenses for projects subject to sections 14 and 15 of the Federal Power Act.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Annual licenses for projects subject to sections 14 and 15 of the Federal Power Act. 16.18 Section 16.18 Conservation of Power... Projects Subject to Sections 14 and 15 of the Federal Power Act § 16.18 Annual licenses for projects...

18 CFR 16.18 - Annual licenses for projects subject to sections 14 and 15 of the Federal Power Act.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Annual licenses for projects subject to sections 14 and 15 of the Federal Power Act. 16.18 Section 16.18 Conservation of Power... Projects Subject to Sections 14 and 15 of the Federal Power Act § 16.18 Annual licenses for projects...

Digitization of Blocks and Virtual Anastylosis of AN Antique Facade in Pont-Sainte (france)

NASA Astrophysics Data System (ADS)

Alby, E.; Grussenmeyer, P.; Bitard, L.; Guillemin, S.; Brunet-Gaston, V.; Gaston, C.; Rougier, R.

2017-08-01

This paper is dedicated to the digitization of blocks and virtual anastylosis of an antique façade in Pont-Sainte-Maxence (France). In 2014 during the construction of a shopping center, the National Institute for Preventive Archaeological Research (INRAP) discovered a Gallo-Roman site from the 2nd century AD. The most interesting part of the site for the study is a façade of 70 meters long by nearly 10 meters high. The state of the conservation of the blocks of the façade makes them exceptional due to the question raised by the collapse. Representative and symbolic blocks of this building have been selected for a virtual anastylosis study. The blocks discovered belong to different types: decorated architectural blocks, monumental statuary elements and details of very fine decorations. The digital reproduction of the façade will facilitate the formulation of hypothesis for the collapse of the structure. The Photogrammetry and Geomatics Group from INSA Strasbourg is in charge of the digitization, the anastylosis and the development of exploratory methods for understanding the ruin of the façade. To develop the three-dimensional model of the facade, approximately 70 blocks of various dimensions were chosen by the archaeologists. The choice of the digitization technique is made according to the following pragmatic criterion: the movable objects are acquired with a scan-arm or a hand-held scanner in the laboratory and the largest blocks are recorded by photogrammetry at the repository near Paris. The expected types of deliverables are multiple: very accurate 3D models with the most faithful representation to document the objects in the best way and with optimized size model allowing easy handling during anastylosis tests. The visual aspect of the models is also a very important issue. Indeed, textures from photos are an excellent way to bring about the realism of the virtual model, but fine details of the object are sometimes blurred by the uniformity of the color

Earthquake Magnitude Relationships for the Saint Peter and Saint Paul Archipelago, Equatorial Atlantic

NASA Astrophysics Data System (ADS)

de Melo, Guilherme W. S.; do Nascimento, Aderson F.

2018-03-01

We have investigated several relationships between ML, M(NEIC) and Mw for the earthquakes locally recorded in the Saint Peter and Saint Paul Archipelago (SPSPA), Equatorial Atlantic. Because we only have one station in the area, we could not derive attenuation relations for events recorded at different distances at different stations. Our approach was then to compare our ML estimates with magnitudes reported by NEIC. This approach produced acceptable results particularly for epicentral distance smaller than 100 km. For distances greater that 100 km, there is a systematic increase in the residuals probable due to the lack of station correction and our inability to accurately estimate Q. We also investigate the Mw—M(NEIC) relationship. We find that Mw estimates using S-wave produce smaller residuals when compared with both M(NEIC). Finally, we also investigate the ML—Mw relationship and observe that given the data set we have, the 1:1 holds. We believe that the use of the present methodologies provide consistent magnitude estimates between all the magnitudes investigated that could be used to better assess seismic hazard in the region.

Earthquake Magnitude Relationships for the Saint Peter and Saint Paul Archipelago, Equatorial Atlantic

NASA Astrophysics Data System (ADS)

de Melo, Guilherme W. S.; do Nascimento, Aderson F.

2017-12-01

We have investigated several relationships between ML, M(NEIC) and Mw for the earthquakes locally recorded in the Saint Peter and Saint Paul Archipelago (SPSPA), Equatorial Atlantic. Because we only have one station in the area, we could not derive attenuation relations for events recorded at different distances at different stations. Our approach was then to compare our ML estimates with magnitudes reported by NEIC. This approach produced acceptable results particularly for epicentral distance smaller than 100 km. For distances greater that 100 km, there is a systematic increase in the residuals probable due to the lack of station correction and our inability to accurately estimate Q. We also investigate the Mw—M(NEIC) relationship. We find that Mw estimates using S-wave produce smaller residuals when compared with both M(NEIC). Finally, we also investigate the ML—Mw relationship and observe that given the data set we have, the 1:1 holds. We believe that the use of the present methodologies provide consistent magnitude estimates between all the magnitudes investigated that could be used to better assess seismic hazard in the region.

78 FR 21233 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-10

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... (NPRM), which proposed to amend 14 CFR part 39 to include an AD that would apply to Eurocopter France...

30 CFR 18.14 - Identification of tested noncertified explosion-proof enclosures.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Identification of tested noncertified explosion-proof enclosures. 18.14 Section 18.14 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MOTOR-DRIVEN MINE EQUIPMENT...

Umbilical hernia with cholelithiasis and hiatal hernia: a clinical entity similar to Saint's triad.

PubMed

Yamanaka, Takahiro; Miyazaki, Tatsuya; Kumakura, Yuji; Honjo, Hiroaki; Hara, Keigo; Yokobori, Takehiko; Sakai, Makoto; Sohda, Makoto; Kuwano, Hiroyuki

2015-01-01

We experienced two cases involving the simultaneous presence of cholelithiasis, hiatal hernia, and umbilical hernia. Both patients were female and overweight (body mass index of 25.0-29.9 kg/m(2)) and had a history of pregnancy and surgical treatment of cholelithiasis. Additionally, both patients had two of the three conditions of Saint's triad. Based on analysis of the pathogenesis of these two cases, we consider that these four diseases (Saint's triad and umbilical hernia) are associated with one another. Obesity is a common risk factor for both umbilical hernia and Saint's triad. Female sex, older age, and a history of pregnancy are common risk factors for umbilical hernia and two of the three conditions of Saint's triad. Thus, umbilical hernia may readily develop with Saint's triad. Knowledge of this coincidence is important in the clinical setting. The concomitant occurrence of Saint's triad and umbilical hernia may be another clinical "tetralogy."

Resource Use and Cost of Alzheimer's Disease in France: 18-Month Results from the GERAS Observational Study.

PubMed

Rapp, Thomas; Andrieu, Sandrine; Chartier, Florence; Deberdt, Walter; Reed, Catherine; Belger, Mark; Vellas, Bruno

2018-03-01

There is little longitudinal data on resource use and costs associated with Alzheimer's disease (AD) in France. To evaluate resource use and societal costs associated with AD in a French cohort of patients and their caregivers and the effect of patient cognitive decline on costs over an 18-month period. Community-dwelling patients with mild, moderate, or moderately severe/severe AD dementia (n = 419) were followed-up for 18 months. Total societal costs were estimated by applying 2010 unit costs to resource use, including outpatient visits, hospital days, institutionalization, and caregiver hours. Cognitive function was assessed by Mini-Mental State Examination scores. Mean cumulative total costs over the 18-month period were €24,140 for patients with mild AD dementia, €34,287 for those with moderate AD dementia, and €44,171 for those with moderately severe/severe AD dementia (P < 0.001; ANOVA comparison between severity groups). The biggest contributor to total societal costs was caregiver informal care (>50% of total costs at all stages of AD dementia). Cognitive decline (≥3-point decrease in Mini-Mental State Examination score or institutionalization) was associated with a 12.5% increase in total costs (P = 0.02). Significant differences were observed across severity groups for caregiver time (P < 0.001); mean monthly caregiver time increased at each time point over the 18 months in each severity group. Increasing severity of AD dementia in France is associated with increased use of resources as well as increased total societal and patient costs; informal care was the greatest cost contributor. Clinically meaningful cognitive decline is associated with significantly increased costs. Copyright © 2018 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

77 FR 56755 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-14

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... proposed to amend 14 CFR part 39 to include an AD that would apply to Eurocopter France Model SA341G...

77 FR 43738 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-26

...-0772; Directorate Identifier 2007-SW-053-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... manufactured in France and is type certificated for operation in the United States under the provisions of 14...

3-D Perspective View, Miquelon and Saint Pierre Islands

NASA Technical Reports Server (NTRS)

2000-01-01

This image shows Miquelon and Saint Pierre Islands, located south of Newfoundland, Canada. These islands, along with five smaller islands, are a self-governing territory of France. North is in the top right corner of the image. The island of Miquelon, in the background, is divided by a thin barrier beach into Petite Miquelon on the left, and Grande Miquelon on the right. Saint Pierre Island is seen in the foreground. The maximum elevation of this land is 240 meters (787 feet). The land mass of the islands is about 242square kilometers (94 square miles) or 1.5 times the size of Washington, DC.

This three-dimensional perspective view is one of several still photographs taken from a simulated flyover of the islands. It shows how elevation data collected by the Shuttle Radar Topography Mission (SRTM) can be used to enhance other satellite images. Color and natural shading are provided by a Landsat 7 image taken on September 7, 1999. The Landsat image was draped over the SRTM data. Terrain perspective and shading are from SRTM. The vertical scale has been increased six times to make it easier to see the small features. This also makes the sea cliffs around the edges of the islands look larger. In this view the capital city of Saint Pierre is seen as the bright area in the foreground of the island. The thin bright line seen in the water is a breakwater that offers some walled protection for the coastal city.

Elevation data used in this image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on February 11,2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and

29 CFR 18.14 - Scope of discovery.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Secretary of Labor RULES OF PRACTICE AND PROCEDURE FOR ADMINISTRATIVE HEARINGS BEFORE THE OFFICE OF ADMINISTRATIVE LAW JUDGES General § 18.14 Scope of discovery. (a) Unless otherwise limited by order of the administrative law judge in accordance with these rules, the parties may obtain discovery regarding any matter...

The Saint Louis River Idea-Slam crowd sourcing good ideas for the Saint Louis River

EPA Science Inventory

As part of the 2017 Saint Louis River Summit, we propose hosting an “Idea-Slam” using software originally developed by the U.S. Consumer Financial Protection Bureau. Idea-box is an open source online app/website used to collect and surface ideas from members of an or...

Defense.gov - Special Report - D-Day: 65th Anniversary - June 6, 1944

Science.gov Websites

Bread With French Family SAINTE MERE EGLISE, France, June 4, 2009 - Army Spc. Adrienne Killingsworth lifetime. Story Rennactors Bring D-Day Era Alive SAINTE MERE EGLISE, France, June 4, 2009 - Maurice anniversary of D-Day. Story Soldier Pays Tribute to Forebears With Service NORMANDY, France, June 4, 2009

International Conference on Curves and Surfaces (4th), Saint-Malo, France, 1-7 July 1999. Proceedings, Volume 1. Curve and Surface Design

DTIC Science & Technology

2000-04-01

the Air Force grant issued by the European Aerospace Office of Research and Development. The United States has a royalty free license throughout the...UNIVERSITY PRESS Nashville fl9 ~Oc -O i U.S. Government Rights License This work relates to Department of the Air Force Grant/rContract issued by the...in engineering , medicine, and the sciences. SERIES EDITOR: Larry L. Schumaker Stevenson Professor of Mathematics Vanderbilt University PREVIOUSLY

The harmonious relationship between faith and science from the perspective of some great saints: A brief comment.

PubMed

Cortés, Manuel E; Del Río, Juan Pablo; Vigil, Pilar

2015-02-01

The objective of this editorial is to show that a harmonious relationship between science and faith is possible, as exemplified by great saints of the Catholic Church. It begins with the definitions of science and faith, followed by an explanation of the apparent conflict between them. A few saints that constitute an example that a fruitful relationship between these two seemingly opposed realities has been possible are Saint Albert the Great, Saint John of the Cross, Saint Giuseppe Moscati, and Saint Edith Stein, among others, and this editorial highlights their deep contributions to the dialogue between faith and reason. This editorial ends with a brief discussion on whether it is possible to be both a scientist and a man of faith.

The harmonious relationship between faith and science from the perspective of some great saints: A brief comment

PubMed Central

Cortés, Manuel E.; del Río, Juan Pablo; Vigil, Pilar

2015-01-01

The objective of this editorial is to show that a harmonious relationship between science and faith is possible, as exemplified by great saints of the Catholic Church. It begins with the definitions of science and faith, followed by an explanation of the apparent conflict between them. A few saints that constitute an example that a fruitful relationship between these two seemingly opposed realities has been possible are Saint Albert the Great, Saint John of the Cross, Saint Giuseppe Moscati, and Saint Edith Stein, among others, and this editorial highlights their deep contributions to the dialogue between faith and reason. This editorial ends with a brief discussion on whether it is possible to be both a scientist and a man of faith. PMID:25698837

18. MAINTENANCE SHOP, FIRST FLOOR, INTERIOR, ENGINE AND AIRPLANE OVERHAUL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. MAINTENANCE SHOP, FIRST FLOOR, INTERIOR, ENGINE AND AIRPLANE OVERHAUL AREAS; LOOKING EAST - Northwest Airways Hangar & Administration Building, 590 Bayfield Street, St. Paul Downtown Airport (Holman), Saint Paul, Ramsey County, MN

Interannual (1999-2005) morphodynamic evolution of macro-tidal salt marshes in Mont-Saint-Michel Bay (France)

NASA Astrophysics Data System (ADS)

Détriché, Sébastien; Susperregui, Anne-Sophie; Feunteun, Eric; Lefeuvre, Jean-Claude; Jigorel, Alain

2011-04-01

This paper provides a detailed study on the sedimentation patterns and the recent morphodynamic evolution affecting the macro-tidal salt marshes located west of the Mont-Saint-Michel (France). Twenty-two stations along three transects on the marshes were seasonally monitored for marsh surface level variations from 1999 to 2005, using a sediment erosion bar. The corresponding erosion/accretion rates were obtained together with data on topography, vegetation cover, and grain size of surface sediment. To examine the mechanisms contributing to the salt marsh sedimentation, the data and their evolution were treated with respect to tides, relative mean regional sea level, and wind speed/frequency variations. From 1999 to 2005, the marsh was globally accreting (from 3.45 to 38.11 mm yr -1 in the low marsh, up to 4.91 mm yr -1 in the middle marsh, and up to 1.35 mm yr -1 in the high marsh), while the study was conducted during a window of decreasing trend in mean regional sea level (-2.45 mm yr -1 according to regional-averaged time series). These sedimentation rates are one of the highest recorded worldwide; however, the sedimentation was not found to be continuous over the period in question. This pattern is illustrated by the strong extension of the marshes from 1999 to 2002, and the relative stability observed from 2003 to 2005. The imported and reworked sediments are trapped and fixed by the dense vegetation ( Puccinellia maritima, Halimione portulacoides), inducing the general seaward extension of the marshes. The processes governing sediment budget (accretion/erosion) show annual, seasonal, and spatial variability on the marsh. Spatial variations display contrasted patterns of erosion/sedimentation between the low, middle, and high marsh, and between the different transects. These patterns are a result of distance from sediment sources, strong heterogeneity in vegetation cover (human induced or not), and contrasting topographic and micro-topographic characteristics

Molecular epidemiology of penicillinase-producing Neisseria gonorrhoeae isolates in France.

PubMed

Micaëlo, M; Goubard, A; La Ruche, G; Denamur, E; Tenaillon, O; Cambau, E; Jacquier, H; Bercot, B

2017-12-01

Characterizing the molecular epidemiology of antibiotic resistance is crucial for a better understanding of the evolution and spread of resistance in Neisseria gonorrhoeae. Here, we examine the molecular epidemiology of penicillinase-producing N. gonorrhoeae (PPNG) isolates in France. We investigated 176 PPNG isolates collected between 2010 and 2012 by the National Reference Centre in France. Genotyping was performed using the NG-MAST technique, bla TEM genes were Sanger-sequenced, and plasmids were characterized by PCR-typing. We revealed the existence of four major clusters representing about one-third of PPNG circulating in France. These clusters were related to ST1479 (18/176, 10.2%), to ST1582 (15/176, 8.5%), to ST8922 (10/176, 5.6%), and to ST1285 (9/176, 5.1%). Wild-type TEM-1 was identified in 151 (151/176, 85.8%) PPNG isolates, and TEM-1 variants were mostly represented by the M182T mutation (14/176, 8%), followed by P14S/L (8/176, 4.5%), G228S (2/176, 1.1%), and Q269K (1/176, 0.6%). The bla TEM genes were carried by African (157/176, 89.2%), Asian (13/176, 7.4%), and Toronto/Rio (6/176, 3.4%) plasmids. The M182T variants were found in various genetic backgrounds, whereas the P14S variants were disseminated clonally. The G228S and Q269K variants belong to one of the four major clusters of PPNG, which suggests a recent de novo emergence of these mutations. Our results show that approximately one-third of the penicillinase-producing N. gonorrhoeae isolates in France belong to one of four major clusters and that the spread of the different TEM variants is associated with distinct patterns of molecular epidemiology. Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Accuracy of diagnosis criteria in patients with suspected diagnosis of sporadic Creutzfeldt-Jakob disease and detection of 14-3-3 protein, France, 1992 to 2009

PubMed Central

Peckeu, Laurene; Delasnerie-Lauprètre, Nicole; Brandel, Jean-Philippe; Salomon, Dominique; Sazdovitch, Véronique; Laplanche, Jean-Louis; Duyckaerts, Charles; Seilhean, Danielle; Haïk, Stéphane; Hauw, Jean-Jacques

2017-01-01

Diagnostic criteria of Creutzfeldt–Jakob disease (CJD), a rare and fatal transmissible nervous system disease with public health implications, are determined by clinical data, electroencephalogram (EEG), detection of 14-3-3 protein in cerebrospinal fluid (CSF), brain magnetic resonance imaging and prion protein gene examination. The specificity of protein 14-3-3 has been questioned. We reviewed data from 1,572 autopsied patients collected over an 18-year period (1992–2009) and assessed whether and how 14-3-3 detection impacted the diagnosis of sporadic CJD in France, and whether this led to the misdiagnosis of treatable disorders. 14-3-3 detection was introduced into diagnostic criteria for CJD in 1998. Diagnostic accuracy decreased from 92% for the 1992–1997 period to 85% for the 1998–2009 period. This was associated with positive detections of 14-3-3 in cases with negative EEG and alternative diagnosis at autopsy. Potentially treatable diseases were found in 163 patients (10.5%). This study confirms the usefulness of the recent modification of diagnosis criteria by the addition of the results of CSF real-time quaking-induced conversion, a method based on prion seed-induced misfolding and aggregation of recombinant prion protein substrate that has proven to be a highly specific test for diagnosis of sporadic CJD. PMID:29043964

Sanctified madness: the God-intoxicated saints of Bengal.

PubMed

Morinis, A

1985-01-01

The saintly madman is a familiar character in South Asia. To outer appearances he is no different from a lunatic, but the mad saint comes to be revered because his idiocy is popularly believed to arise from a different cause than ordinary madness. The common psychopath neglects social conventions because his consciousness is dimmed by incapacity; the saintly madman also breaches convention, but does so because his heightened consciousness has liberated him from the bonds of convention that entrap ordinary people. In the terms of Hinduism, he has tasted the divine nectar of God-realization and has returned to the human realm intoxicated by the experience. In this paper two popular God intoxicated saints of Bengal are discussed. The question is posed whether 'God intoxication' can be considered a culture-bound syndrome of Bengal. The concept of 'culture bound syndrome' is found to be too narrow to encompass the most significant issues to arise from reflection on the characteristics of the God intoxicated. These larger issues have to do with the relationship between cultural practices and models and mental states (whether deviant, as implied by the term 'syndrome' although deviance does not always carry the negative connotation implicit in 'syndrome', or normal). It is suggested that all cultures culture a limited range of mental states and thus the questions posed by the notion of culture bound syndromes are subsumed by larger questions about the relationship of all mind-states to the socio-cultural environment which conditions them. The conclusion is that God intoxication is indeed a uniquely Bengali mental condition, with variants throughout South Asia and kinship to other mystical states, but that the concept of 'syndrome' is not useful.

18. SMALL ALTAR, LOCATED IN EAST END OF NAVE AISLE, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. SMALL ALTAR, LOCATED IN EAST END OF NAVE AISLE, JUST BEHIND APSE. Originally from St. Luke's Episcopal Church (HABS No. SC-535) - Saints Luke & Paul Cathedral, 126 Coming Street, Charleston, Charleston County, SC

Developpements numeriques recents realises en aeroelasticite chez Dassault Aviation pour la conception des avions de combat modernes et des avions d’affaires

DTIC Science & Technology

2003-03-01

combat modernes et des avions d’affaires E. Garrigues, Th. Percheron DASSAULT AVIATION DGT/DTA/IAP F-922 14, Saint-Cloud Cedex France 1. Introduction ...de vol, des acedidrations rigides et des rdponses de la structure ( jauges et acedidrations). Struturl Premdicton Grdjustments n~~~ligh Testsn~n Fig4ure

18 CFR 1309.14 - How will complaints against recipients be processed?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false How will complaints against recipients be processed? 1309.14 Section 1309.14 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY NONDISCRIMINATION WITH RESPECT TO AGE § 1309.14 How will complaints against...

19. Photocopy of October 18, 1903 photograph by Frank Trelease. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

19. Photocopy of October 18, 1903 photograph by Frank Trelease. Glass Negative Box IX, Tower Grove, Missouri Botanical Garden. LOOKING SOUTH FROM GREENHOUSES - Missouri Botanical Garden, 2345 Tower Grove Avenue, Saint Louis, Independent City, MO

French women's knowledge of and attitudes towards cervical cancer prevention and the acceptability of HPV vaccination among those with 14 - 18 year old daughters: a quantitative-qualitative study.

PubMed

Haesebaert, Julie; Lutringer-Magnin, Delphine; Kalecinski, Julie; Barone, Giovanna; Jacquard, Anne-Carole; Régnier, Véronique; Leocmach, Yann; Vanhems, Philippe; Chauvin, Franck; Lasset, Christine

2012-11-27

In France, it is recommended that girls and women aged 14-23 are vaccinated against the human papillomavirus (HPV). However, French women's knowledge of and attitude towards the vaccine has been little studied. Thirty-nine general practitioners, representative of those working in the large Rhône-Alpes region, offered a self-administered questionnaire on cervical cancer (CC) prevention to all 18-65 year-old women who came for consultation during June and July 2008. In addition, semi-structured interviews were undertaken with a sample of those who had daughters aged 14-18. Of the 1,478 women who completed the questionnaire, only 16.9% mentioned HPV as the cause of CC, even though 76.2% knew of the vaccine. 210 women had daughters aged 14-18, and 32 were interviewed. Compared with the wider group, more of these women were aware of the HPV vaccine (91.4%). 44.8% knew the target population and 17.1% the recommended ages for vaccination. 54.3% favoured HPV vaccination; 37.2% were undecided and only 0.9% were opposed. The main barrier to acceptance was the recency of the vaccine's introduction and concern about possible side effects (54.9%); 14.1% preferred to rely on their GP's decision. Factors associated with acceptance of the HPV vaccine were having previously vaccinated a child against pneumococcus (OR=3.28 [1.32-8.11]) and knowing the target population for HPV vaccination (OR=2.12 [1.15-3.90]). Knowing the recommended frequency of Papanicolaou smear testing (Pap test) screening was associated with lower acceptance (OR=0.32 [0.13-0.82]). Few mothers are opposed to HPV vaccination. Factors associated with acceptability were knowledge about the vaccine, acceptance of other vaccines and, unexpectedly, lack of knowledge about the recommended frequency of Pap testing. On multivariate analysis, compliance with recommendations for Pap test screening and socioeconomic factors had no effect on views about HPV vaccination. Given that concern about possible side effects is the

Determinants of tetanus, diphtheria and poliomyelitis vaccinations among Hajj pilgrims, Marseille, France.

PubMed

Gautret, Philippe; Yong, Winnie; Soula, Georges; Parola, Philippe; Brouqui, Philippe; DelVecchio Good, Mary-Jo

2010-08-01

It has been observed that Muslim pilgrims departing France for Mecca have low national immunization rates against tetanus, diphtheria and poliomyelitis (TdP). Our purpose is to identify immigration, socio-economic and socio-cultural determinants of vaccination coverage against TdP. A cross-sectional survey study was conducted in late 2006 among 580 pilgrims in preparation who attended the Infectious and Tropical Medicine ward in Hôpital Nord at Marseille to receive their N. meningitidis vaccine required for travel to Mecca. Total vaccination rates for tetanus (18.9%), diphtheria (14.7%) and poliomyelitis (15.0%) were comparable. Pilgrim's characteristic lower socio-economic and social status, in addition to their unifying linguistic, cultural and religious identity defines them as a particularly disadvantageous group in France. French citizenship, higher level of education, better French fluency and no previous travel to country of origin were the strongest and most significant determinants of TdP vaccination status. These results suggest that the Muslim community in France is at risk from inequities of national preventive care efforts.

Enterovirus Migration Patterns between France and Tunisia

PubMed Central

Othman, Ines; Mirand, Audrey; Slama, Ichrak; Mastouri, Maha; Peigue-Lafeuille, Hélène; Aouni, Mahjoub; Bailly, Jean-Luc

2015-01-01

The enterovirus (EV) types echovirus (E-) 5, E-9, and E-18, and coxsackievirus (CV-) A9 are infrequently reported in human diseases and their epidemiologic features are poorly defined. Virus transmission patterns between countries have been estimated with phylogenetic data derived from the 1D/VP1 and 3CD gene sequences of a sample of 74 strains obtained in France (2000–2012) and Tunisia (2011–2013) and from the publicly available sequences. The EV types (E-5, E-9, and E-18) exhibited a lower worldwide genetic diversity (respective number of genogroups: 4, 5, and 3) in comparison to CV-A9 (n = 10). The phylogenetic trees estimated with both 1D/VP1 and 3CD sequence data showed variations in the number of co-circulating lineages over the last 20 years among the four EV types. Despite the low number of genogroups in E-18, the virus exhibited the highest number of recombinant 3CD lineages (n = 10) versus 4 (E-5) to 8 (E-9). The phylogenies provided evidence of multiple transportation events between France and Tunisia involving E-5, E-9, E-18, and CV-A9 strains. Virus spread events between France and 17 other countries in five continents had high probabilities of occurrence as those between Tunisia and two European countries other than France. All transportation events were supported by BF values > 10. Inferring the source of virus transmission from phylogenetic data may provide insights into the patterns of sporadic and epidemic diseases caused by EVs. PMID:26709514

Enterovirus Migration Patterns between France and Tunisia.

PubMed

Othman, Ines; Mirand, Audrey; Slama, Ichrak; Mastouri, Maha; Peigue-Lafeuille, Hélène; Aouni, Mahjoub; Bailly, Jean-Luc

2015-01-01

The enterovirus (EV) types echovirus (E-) 5, E-9, and E-18, and coxsackievirus (CV-) A9 are infrequently reported in human diseases and their epidemiologic features are poorly defined. Virus transmission patterns between countries have been estimated with phylogenetic data derived from the 1D/VP1 and 3CD gene sequences of a sample of 74 strains obtained in France (2000-2012) and Tunisia (2011-2013) and from the publicly available sequences. The EV types (E-5, E-9, and E-18) exhibited a lower worldwide genetic diversity (respective number of genogroups: 4, 5, and 3) in comparison to CV-A9 (n = 10). The phylogenetic trees estimated with both 1D/VP1 and 3CD sequence data showed variations in the number of co-circulating lineages over the last 20 years among the four EV types. Despite the low number of genogroups in E-18, the virus exhibited the highest number of recombinant 3CD lineages (n = 10) versus 4 (E-5) to 8 (E-9). The phylogenies provided evidence of multiple transportation events between France and Tunisia involving E-5, E-9, E-18, and CV-A9 strains. Virus spread events between France and 17 other countries in five continents had high probabilities of occurrence as those between Tunisia and two European countries other than France. All transportation events were supported by BF values > 10. Inferring the source of virus transmission from phylogenetic data may provide insights into the patterns of sporadic and epidemic diseases caused by EVs.

Radiocarbon dates from the Grotte du Renne and Saint-Césaire support a Neandertal origin for the Châtelperronian

PubMed Central

Hublin, Jean-Jacques; Talamo, Sahra; Julien, Michèle; David, Francine; Connet, Nelly; Bodu, Pierre; Vandermeersch, Bernard; Richards, Michael P.

2012-01-01

The transition from the Middle Paleolithic (MP) to Upper Paleolithic (UP) is marked by the replacement of late Neandertals by modern humans in Europe between 50,000 and 40,000 y ago. Châtelperronian (CP) artifact assemblages found in central France and northern Spain date to this time period. So far, it is the only such assemblage type that has yielded Neandertal remains directly associated with UP style artifacts. CP assemblages also include body ornaments, otherwise virtually unknown in the Neandertal world. However, it has been argued that instead of the CP being manufactured by Neandertals, site formation processes and layer admixture resulted in the chance association of Neanderthal remains, CP assemblages, and body ornaments. Here, we report a series of accelerator mass spectrometry radiocarbon dates on ultrafiltered bone collagen extracted from 40 well-preserved bone fragments from the late Mousterian, CP, and Protoaurignacian layers at the Grotte du Renne site (at Arcy-sur-Cure, France). Our radiocarbon results are inconsistent with the admixture hypothesis. Further, we report a direct date on the Neandertal CP skeleton from Saint-Césaire (France). This date corroborates the assignment of CP assemblages to the latest Neandertals of western Europe. Importantly, our results establish that the production of body ornaments in the CP postdates the arrival of modern humans in neighboring regions of Europe. This new behavior could therefore have been the result of cultural diffusion from modern to Neandertal groups. PMID:23112183

Prayer to the Saints or the Virgin And Health Among Older Mexican Americans

PubMed Central

Krause, Neal; Bastida, Elena

2011-01-01

The purpose of this study was to evaluate a conceptual model that assesses whether praying to the saints or the Virgin is associated with the health of older Mexican Americans. A survey was conducted of 1,005 older Mexican Americans (Mean age = 73.9 years; SD = 6.6 years). Data from 795 of the Catholic respondents are presented in this study. The findings support the following relationships that are embedded in the conceptual model: (1) older Mexican Americans who attend church more often are more likely to believe in the efficacy of prayer to the saints or the Virgin; (2) stronger beliefs in the efficacy of intercessory prayer are associated with more frequent prayer to the saints or the Virgin; (3) frequent prayer is to the saints or the Virgin is associated with greater God-mediated control beliefs; (4) stronger God-mediated control beliefs are associated with greater optimism; and (5) greater optimism is associated with better self-rated health. PMID:21415935

Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations

PubMed Central

Leich, Ellen; Salaverria, Itziar; Bea, Silvia; Zettl, Andreas; Wright, George; Moreno, Victor; Gascoyne, Randy D.; Chan, Wing-Chung; Braziel, Rita M.; Rimsza, Lisa M.; Weisenburger, Dennis D.; Delabie, Jan; Jaffe, Elaine S.; Lister, Andrew; Fitzgibbon, Jude; Staudt, Louis M.; Hartmann, Elena M.; Mueller-Hermelink, Hans-Konrad; Campo, Elias; Ott, German

2009-01-01

Follicular lymphoma (FL) is genetically characterized by the presence of the t(14;18)(q32;q21) chromosomal translocation in approximately 90% of cases. In contrast to FL carrying the t(14;18), their t(14;18)-negative counterparts are less well studied about their immunohistochemical, genetic, molecular, and clinical features. Within a previously published series of 184 FLs grades 1 to 3A with available gene expression data, we identified 17 FLs lacking the t(14;18). Comparative genomic hybridization and high-resolution single nucleotide polymorphism (SNP) array profiling showed that gains/amplifications of the BCL2 gene locus in 18q were restricted to the t(14;18)-positive FL subgroup. A comparison of gene expression profiles showed an enrichment of germinal center B cell–associated signatures in t(14;18)-positive FL, whereas activated B cell–like, NFκB, proliferation, and bystander cell signatures were enriched in t(14;18)-negative FL. These findings were confirmed by immunohistochemistry in an independent validation series of 84 FLs, in which 32% of t(14;18)-negative FLs showed weak or absent CD10 expression and 91% an increased Ki67 proliferation rate. Although overall survival did not differ between FL with and without t(14;18), our findings suggest distinct molecular features of t(14;18)-negative FL. PMID:19471018

Evidence supporting an intentional Neandertal burial at La Chapelle-aux-Saints.

PubMed

Rendu, William; Beauval, Cédric; Crevecoeur, Isabelle; Bayle, Priscilla; Balzeau, Antoine; Bismuth, Thierry; Bourguignon, Laurence; Delfour, Géraldine; Faivre, Jean-Philippe; Lacrampe-Cuyaubère, François; Tavormina, Carlotta; Todisco, Dominique; Turq, Alain; Maureille, Bruno

2014-01-07

The bouffia Bonneval at La Chapelle-aux-Saints is well known for the discovery of the first secure Neandertal burial in the early 20th century. However, the intentionality of the burial remains an issue of some debate. Here, we present the results of a 12-y fieldwork project, along with a taphonomic analysis of the human remains, designed to assess the funerary context of the La Chapelle-aux-Saints Neandertal. We have established the anthropogenic nature of the burial pit and underlined the taphonomic evidence of a rapid burial of the body. These multiple lines of evidence support the hypothesis of an intentional burial. Finally, the discovery of skeletal elements belonging to the original La Chapelle aux Saints 1 individual, two additional young individuals, and a second adult in the bouffia Bonneval highlights a more complex site-formation history than previously proposed.

77 FR 63262 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-16

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2012-1087; Directorate Identifier 2009-SW-32-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... France: Docket No. FAA-2012-1087; Directorate Identifier 2009-SW-32-AD. (a) Applicability This AD applies...

History of the Redstone Missile System

DTIC Science & Technology

1965-10-15

knowledge in areas such as propulsion systems, rocket fuels, aerodynamics, guidance equipment, and’testing equipment. It compiled basic statistics on...i n g of t he 46th and 4 3 Tech Rept, ABMA, 30 Jun 57, sub: Ordnance Guided M i s s i l e and Rocket Programs, Redstone, Vol. IVg Supp. 2, p. 67...embarked in June for Europe. The main body boarded ship on 18 June 1958 for Saint-Nazaire, France , and moved in convoy across France and 48~ept

Analytical characterization of ch14.18

PubMed Central

Kallarakal, Abraham T; Michiel, Dennis; Yang, Xiaoyi; Saptharishi, Nirmala; Jiang, Hengguang; Giardina, Steve; Gilly, John; Mitra, George

2012-01-01

Ch14.18 is a mouse-human chimeric monoclonal antibody to the disialoganglioside (GD2) glycolipid. In the clinic, this antibody has been shown to be effective in the treatment of children with high-risk neuroblastoma, either alone or in combination therapy. Extensive product characterization is a prerequisite to addressing the potential issues of product variability associated with process changes and manufacturing scale-up. Charge heterogeneity, glycosylation profile, molecular state and aggregation, interaction (affinity) with Fcγ receptors and functional or biological activities are a few of the critical characterization assays for assessing product comparability for this antibody. In this article, we describe the in-house development and qualification of imaged capillary isoelectric focusing to assess charge heterogeneity, analytical size exclusion chromatography with online static and dynamic light scattering (DLS), batch mode DLS for aggregate detection, biosensor (surface plasmon resonance)-based Fcγ receptor antibody interaction kinetics, N-glycoprofiling with PNGase F digestion, 2-aminobenzoic acid labeling and high performance liquid chromatography and N-glycan analysis using capillary electrophoresis. In addition, we studied selected biological activity assays, such as complement-dependent cytotoxicity. The consistency and reproducibility of the assays are established by comparing the intra-day and inter-day assay results. Applications of the methodologies to address stability or changes in product characteristics are also reported. The study results reveal that the ch14.18 clinical product formulated in phosphate-buffered saline at a concentration of 5 mg/ml and stored at 2–8°C is stable for more than five years. PMID:22327432

Perspectives on the New Orleans Saints as a Vehicle for the Installation of Hope, Post Katrina: Therapy on the 30 Yard Line

ERIC Educational Resources Information Center

Lawrence, Christopher

2007-01-01

The author discusses the effectiveness of popular culture as a tool for the instillation of hope within a community, using as an example the ways in which a National Football League team galvanized the residents of New Orleans in the 18 months following Hurricane Katrina. This article posits that the Saints supplied an impetus for transcendence…

Exposure of hairdressers to the main cosmetics used in hairdressing salons in France: A preliminary study.

PubMed

Ramirez-Martinez, A; Granda-Torres, P; Wesolek, N; Ficheux, A S; Roudot, A C

2016-09-02

In recent years, more attention has been given to chemical exposure in hairdressers. This increasing interest is largely due to the various respiratory and skin symptoms observed in hairdressers. According to these symptoms, hairdressers are in contact with various sources of exposure. Particularly in France, little information is available to assess professional exposure of hairdressers. In order to gather information to assess exposure in hairdressers, 11 hairdressing salons were visited. All the salons were located in Brest City (France). Preferentially, small hairdressing salons were visited. Observations were performed to obtain salon characteristics and to record workers' practices. Calculations revealed that in the worst-case scenario, dermal professional exposure reaches 14.68 and 13.67 mg/kg/day for hair coloring and highlighting mixtures, respectively. Inhalation exposure represents 14.2 and 18.1 mg/kg/day for hair coloring and highlighting mixtures, respectively. These exposure values represent baseline values for exposure of French hairdressers working in small hairdressing salons.

Prevalence of fibrodysplasia ossificans progressiva (FOP) in France: an estimate based on a record linkage of two national databases.

PubMed

Baujat, Geneviève; Choquet, Rémy; Bouée, Stéphane; Jeanbat, Viviane; Courouve, Laurène; Ruel, Amélie; Michot, Caroline; Le Quan Sang, Kim-Hanh; Lapidus, David; Messiaen, Claude; Landais, Paul; Cormier-Daire, Valérie

2017-06-30

Fibrodysplasia ossificans progressiva (FOP) is a rare, severely disabling, and life-shortening genetic disorder that causes the formation of heterotopic bone within soft connective tissue. Previous studies found that the FOP prevalence was about one in every two million lives. The aim of this study is to estimate the FOP prevalence in France by probabilistic record-linkage of 2 national databases: 1) the PMSI (Programme de médicalisation des systèmes d'information), an administrative database that records all hospitalization activities in France and 2) CEMARA, a registry database developed by the French Centres of Reference for Rare Diseases. Using a capture-recapture methodology to adjust the crude number of patients identified in both data sources, 89 FOP patients were identified, which results in a prevalence of 1.36 per million inhabitants (CI95% = [1.10; 1.68]). FOP patients' mean age was 25 years, only 14.9% were above 40 years, and 53% of them were males. The first symptoms - beside toe malformations- occurred after birth for 97.3% of them. Mean age at identified symptoms was 7 years and above 18 years for only 6.9% of patients. Mean age at diagnosis was 10 years, and above 18 years for 14.9% of the patients. FOP patients were distributed across France. Despite the challenge of ascertaining patients with rare diseases, we report a much higher prevalence of FOP in France than in previous studies elsewhere. We suggest that efforts to identify patients and confirm the diagnosis of FOP should be reinforced and extended at both national and European level.

The Obscurantist Design in Saint Augustine's Rhetoric.

ERIC Educational Resources Information Center

Wiethoff, William E.

This paper examines Saint Augustine's obscurantist preferences in popular preaching (as distinguished from his episcopal instructions to other clergy) as a way of identifying one of the classical influences on Christian rhetorical strategy. The first section of the paper offers a comparison of Augustine's theoretical approval of homiletic…

Shaded Relief Image of Saint Pierre and Miquelon

NASA Technical Reports Server (NTRS)

2000-01-01

This image shows two islands, Miquelon and Saint Pierre, located south of Newfoundland, Canada. These islands, along with five smaller islands, are a self-governing territory of France. A thin barrier beach divides Miquelon, with Grande Miquelon to the north and Petite Miquelonto the south. Saint Pierre Island is located to the lower right. With the islandsi location in the north Atlantic Ocean and their deep water ports, fishing is the major part of the economy. The maximum elevation of the island is 240 meters (787 feet). The land mass of the islands is about 242 square kilometers, or 1.5 times the size of Washington DC.

This shaded relief image was generated using topographic data from the Shuttle Radar Topography Mission. A computer-generated artificial light source illuminates the elevation data to produce a pattern of light and shadows. Slopes facing the light appear bright, while those facing away are shaded. On flatter surfaces, the pattern of light and shadows can reveal subtle features in the terrain. Shaded relief maps are commonly used in applications such as geologic mapping and land use planning.

This image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on February 11, 2000. SRTM uses the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. The mission is designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between the National Aeronautics and Space Administration (NASA), the National Imagery and Mapping Agency (NIMA) of the U.S. Department of Defense (DoD), and the German and Italian space agencies. It is managed by NASAis Jet Propulsion

Microseismic noise in the Saint Peter and Saint Paul Archipelago, equatorial Atlantic

NASA Astrophysics Data System (ADS)

de Queiroz, Daniel É.; do Nascimento, Aderson F.; Schimmel, Martin

2017-12-01

Microseismic noise, also known as ambient seismic noise, are continuous vibrations mostly composed of Rayleigh waves pervasively recorded in the mili Hertz to 1 Hz frequency range. Their precise source mechanisms are under investigations and related to atmospheric perturbations and ocean gravity waves. Our purpose is to show the behavior of the microseismic noise recorded in the Saint Peter and Saint Paul Archipelago (SPSPA) with respect to wind intensity and ocean waves height in this region, between the North and South Atlantic Ocean. We have recorded both primary microseisms (PM) 0.04-0.12 Hz and the secondary microseisms (SM) 0.12-0.4 Hz during almost four years (2012-2015) and we used frequency, temporal, spatial and statistical correlation analysis to do qualitative and quantitative analysis with respect to wind speed intensity and significant wave height for the same periods. The results indicate a good correlation between the PM and the SM noise in the region particularly during the winter in the Northern Hemisphere and a poor correlation during the summer. We have also shown that probably most of the PM are generated in the SPSPA itself. We note that the intensity of SM recorded in SPSPA appears to have a seasonal behavior with the summer and winter in the Northern Hemisphere, and seems to influence the correlation between the PM and the SM, suggesting that the sources of the PM and the SM are not related to the same atmospheric event and from different places. PM generation would occur near the SPSPA whilst the SM would have distant sources towards the North Atlantic.

Individual Susceptibility to NTHL and New Perspective in Treatment of Acute Noise Trauma

DTIC Science & Technology

2000-09-01

Treatment of Acute Noise Trauma A.L. Dancer French -German Research Institute of Saint-Louis BP 34, 5 rue du Gal. Cassagnou 68301 Saint-Louis Cedex France ...individuals. It is possible that a 1. Introduction test of susceptibility to PTS based on TTS measures may In some countries ( France , Germany...) all...rather a lot of treatment at the hospital. In France , for the three years inconsistencies. Therefore, some authors [3] decided to 1993, 1994 and 1995

76 FR 81430 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-28

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2011-1408; Directorate Identifier 2008-SW-10-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... [Amended] 2. The FAA amends Sec. 39.13 by adding the following new AD: Eurocopter France: Docket No. FAA...

Medico-legal investigations of the Airbus, A320 crash upon Mount Ste-Odile, France.

PubMed

Ludes, B; Tracqui, A; Pfitzinger, H; Kintz, P; Levy, F; Disteldorf, M; Hutt, J M; Kaess, B; Haag, R; Memheld, B

1994-09-01

The authors present the medico-legal investigations and identification after the aircrash of the Airbus A320 upon the Mount Sainte-Odile (France). The identification team comprising investigators from the gendarmerie, forensic pathologists, odontologists, and scientists of the Institute from Legal Medecine rapidly retrieved and identified 85 of the 87 victims, with 17 being identified through DNA typing, three through fingerprints and the remaining through dental records and specific physical or X-ray findings. Full autopsies were performed on all fatalities to determine patterns of injury and cause of death. Results lead us to point out the importance of a multidisciplinary team of forensic practitioners especially trained for managing medico-legal investigation in mass disaster and the ability of DNA technology to solve complex identification problems.

18 CFR 284.14 - Posting requirements of major non-interstate pipelines.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Posting requirements of major non-interstate pipelines. 284.14 Section 284.14 Conservation of Power and Water Resources FEDERAL... to or greater than 15,000 MMBtu (million British thermal units)/day; or (ii) If a physically metered...

18 CFR 284.14 - Posting requirements of major non-interstate pipelines.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Posting requirements of major non-interstate pipelines. 284.14 Section 284.14 Conservation of Power and Water Resources FEDERAL... to or greater than 15,000 MMBtu (million British thermal units)/day; or (ii) If a physically metered...

18 CFR 284.14 - Posting requirements of major non-interstate pipelines.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Posting requirements of major non-interstate pipelines. 284.14 Section 284.14 Conservation of Power and Water Resources FEDERAL... to or greater than 15,000 MMBtu (million British thermal units)/day; or (ii) If a physically metered...

18 CFR 284.14 - Posting requirements of major non-interstate pipelines.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Posting requirements of major non-interstate pipelines. 284.14 Section 284.14 Conservation of Power and Water Resources FEDERAL... to or greater than 15,000 MMBtu (million British thermal units)/day; or (ii) If a physically metered...

18 CFR 284.14 - Posting requirements of major non-interstate pipelines.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Posting requirements of major non-interstate pipelines. 284.14 Section 284.14 Conservation of Power and Water Resources FEDERAL... to or greater than 15,000 MMBtu (million British thermal units)/day; or (ii) If a physically metered...

Biology of Grapsus grapsus (L innaeus, 1758) (Brachyura, Grapsidae) in the Saint Peter and Saint Paul Archipelago, Equatorial Atlantic Ocean

NASA Astrophysics Data System (ADS)

Freire, A. S.; Pinheiro, M. A. A.; Karam-Silva, H.; Teschima, M. M.

2011-09-01

Eleven expeditions were undertaken to the Saint Peter and Saint Paul Archipelago to study the reproductive biology of Grapsus grapsus, providing additional information on limb mutilation and carapace colour. MATURE software was used to estimate morphological maturity, while gonadal analyses were conducted to estimate physiological maturity. The puberty moult took place at larger size in males (51.4 mm of carapace length) than in females (33.8 mm), while physiological maturity occurred at a similar size in males (38.4 mm) and in females (33.4 mm). Above 50 mm, the proportion of red males increased in the population, indicating that functional maturity is also related to colour pattern. Small habitat and high local population density contributed to the high rate of cannibalism. The low diversity of food items, absence of predators of large crabs and high geographic isolation are the determinants of unique behavioural and biological characteristics observed in the G. grapsus population.

The implication of follicular lymphoma patients receiving allogeneic stem cell transplantation from donors carrying t(14;18)-positive cells.

PubMed

McGregor, D K; Keever-Taylor, C A; Bredeson, C; Schur, B; Vesole, D H; Logan, B; Chang, C-C

2005-06-01

We performed real-time quantitative polymerase chain reaction (RQ-PCR) in peripheral blood (PB) and/or bone marrow (BM) samples collected pre- and post transplant from 23 recipient-donor pairs receiving allogeneic stem cell transplantation (allo-SCT) for follicular lymphoma (FL). Of 23 donors, 11 had a PB and/or BM sample positive for t(14;18) (BCL2/IGH fusion) at low levels (14;18) cell in 10K total cells). Recipients from donors with (n=11) and those without (n=12) detectable t(14:18) cells were similar in age, sex, and disease status pretransplant. No differences in the incidence of graft-versus-host-disease (GVHD), delayed engraftment, relapse rate, disease-free survival and overall survival were identified between the groups. Two recipients without detectable t(14;18) cells pre-transplant showed detectable t(14;18) cells at 2 and 11 years after receiving grafts from donors with t(14:18) cells. Neither patient developed FL 1.5 and 2 years after the emergence of t(14;18) cells. Although the sample size is relatively small, our findings suggest that individuals carrying t(14;18) cells may not be excluded as donors given the lack of an association of t(14;18) detected in donors with adverse clinical outcome. It may be necessary to screen for the donor's t(14;18) status before using t(14;18) for monitoring minimal residual disease by RQ-PCR to exclude the possibility of confounding donor's t(14;18) clone.

Pluriannual variability of sedimentation on mudflats in a macrotidal estuary

NASA Astrophysics Data System (ADS)

Cuvilliez, A.; Lafite, R.; Deloffre, J.; Massei, N.; Langlois, E.; Sakho, I.

2010-12-01

Antoine Cuvilliez1, Robert Lafite2, Julien Deloffre2, Nicolas Massei2, Estelle Langlois 3 and Issa Sakho2 1 Université du Havre, FRE 3102, Laboratoire d’ondes et milieux complexes, Université du Havre, 76058 Le Havre cedex, France 2 Université de Rouen, UMR 6143, Morphodynamique Continentale et Côtière, 76821 Mont Saint Aignan Cedex, France. 3 Université de Rouen, ECODIV , Etude et Compréhension de la Biodiversité, 76821 Mont Saint Aignan Cedex, France.

The Saint Mary's Woman: toward Intellectual Leadership.

ERIC Educational Resources Information Center

White, Patrick E.

This two-year project at Saint Mary's College, a women's college in Notre Dame (Indiana), focused on building intellectual community and fostering student leadership skills. The study targeted two student groups: (1) students with much to contribute to the intellectual life of the college but alienated from traditional forms of leadership, and (2)…

Spatial heterogeneity of high-resolution Chalk groundwater geochemistry - Underground quarry at Saint Martin-le-Noeud, France

NASA Astrophysics Data System (ADS)

Barhoum, S.; Valdès, D.; Guérin, R.; Marlin, C.; Vitale, Q.; Benmamar, J.; Gombert, P.

2014-11-01

Chalk groundwater is an important aquifer resource in France because it accounts for a production of 12 million m3 y-1 with a large proportion reserved for drinking water. Processes occurring in the unsaturated zone (UZ) and the overlying superficial formations have a high impact on Chalk groundwater geochemistry and require better understanding. The study site is a former underground Chalk quarry located near Beauvais (France) that extends over 1200 m in length, at a depth ranging from 20 to 30 m. The water table intersects the cavity creating 15 underground ;lake; that give access to the Chalk groundwater. Lakes geochemistry has been studied: water samples were collected in July 2013 and major ion concentrations were analyzed. UZ and clay-with-flints thickness above each lake were estimated qualitatively using an electromagnetic sensor (EM31) and Underground GPS. The results unexpectedly showed that groundwater quality varied widely in spatial terms for both allochthonous and autochthonous ions (e.g., HCO3- ranged from 2.03 to 4.43 meq L-1, NO3- ranged from 0.21 to 1.33 meq L-1). Principal component analysis indicated the impact of agricultural land use on water quality, with the intake of NO3- as well as SO42-, Cl- and Ca2+. Chalk groundwater geochemistry is compared with the nature and structure of the UZ. We highlight correlations (1) between thick clay-with-flints layers and the ions Mg2+ and K+, and (2) between UZ thickness and Na+. In conclusion, this paper identifies various ion sources (agriculture, clay-with-flints and Chalk) and demonstrates different processes in the UZ: dissolution, ionic exchange and solute storage.

Overview of environmental and hydrogeologic conditions at Saint Marys, Alaska

USGS Publications Warehouse

Nakanishi, Allan S.; Dorava, Joseph M.

1994-01-01

The Federal Aviation Administration (FAA) owns or operates airway support facilities near Saint Marys along the Yukon River in west-central Alaska. The FAA is evaluating the severity of environmental contamination and options for remediation of environmental contamination at their facilities. Saint Marys is on a flood plain near the continence of the Yukon and Andreafsky Rivers and has long cold winters and short summers. Residents obtain their drinking water from an infiltration gallery fed by a creek near the village. Surface spills and disposal of hazardous materials combined with potential flooding may affect the quality of the surface and ground water. Alternative drinking-water sources are available, but would likely cost more than existing supplies to develop.

Cost-effectiveness analysis of the introduction of a quadrivalent human papillomavirus vaccine in France.

PubMed

Bergeron, Christine; Largeron, Nathalie; McAllister, Ruth; Mathevet, Patrice; Remy, Vanessa

2008-01-01

A vaccine to prevent diseases due to human papillomavirus (HPV) types 6, 11, 16, and 18 is now available in France. The objective of this study was to assess the health and economic impact in France of implementing a quadrivalent HPV vaccine alongside existing screening practices versus screening alone. A Markov model of the natural history of HPV infection incorporating screening and vaccination, was adapted to the French context. A vaccine that would prevent 100 percent of HPV 6, 11, 16, and 18-associated diseases, with lifetime duration and 80 percent coverage, given to girls at age 14 in conjunction with current screening was compared with screening alone. Results were analyzed from both a direct healthcare cost perspective (DCP) and a third-party payer perspective (TPP). Indirect costs such as productivity loss were not taken into account in this analysis. The incremental cost per life-year gained from vaccination was euro12,429 (TPP) and euro20,455 (DCP). The incremental cost per quality-adjusted life-year (QALY) for the introduction of HPV vaccination alongside the French cervical cancer screening program was euro8,408 (TPP) and euro13,809 (DCP). Sensitivity analyses demonstrated that cost-effectiveness was stable, but was most sensitive to the discount rate used for costs and benefits. Considering the commonly accepted threshold of euro50,000 per QALY, these analyses support the fact that adding a quadrivalent HPV vaccine to the current screening program in France is a cost-effective strategy for reducing the burden of cervical cancer, precancerous lesions, and genital warts caused by HPV types 6, 11, 16, and 18.

14. Photocopy of plan. Original in library of Lehmann Building, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. Photocopy of plan. Original in library of Lehmann Building, Missouri Botanical Garden 1893 PLAN OF GARDEN, SHOWING HENRY SHAW TOWN HOUSE REERECTED (BUILDING V.) - Missouri Botanical Garden, 2345 Tower Grove Avenue, Saint Louis, Independent City, MO

Saint Petersburg magnetic observatory: from Voeikovo subdivision to INTERMAGNET certification

NASA Astrophysics Data System (ADS)

Sidorov, Roman; Soloviev, Anatoly; Krasnoperov, Roman; Kudin, Dmitry; Grudnev, Andrei; Kopytenko, Yury; Kotikov, Andrei; Sergushin, Pavel

2017-11-01

Since June 2012 the Saint Petersburg magnetic observatory is being developed and maintained by two institutions of the Russian Academy of Sciences (RAS) - the Geophysical Center of RAS (GC RAS) and the Saint Petersburg branch of the Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of RAS (IZMIRAN SPb). On 29 April 2016 the application of the Saint Petersburg observatory (IAGA code SPG) for introduction into the INTERMAGNET network was accepted after approval by the experts of the first definitive dataset over 2015, produced by the GC RAS, and on 9 June 2016 the SPG observatory was officially certified. One of the oldest series of magnetic observations, originating in 1834, was resumed in the 21st century, meeting the highest quality standards and all modern technical requirements. In this paper a brief historical and scientific background of the SPG observatory foundation and development is given, the stages of its renovation and upgrade in the 21st century are described, and information on its current state is provided. The first results of the observatory functioning are discussed and geomagnetic variations registered at the SPG observatory are assessed and compared with geomagnetic data from the INTERMAGNET observatories located in the same region.

18 CFR 5.14 - Formal study dispute resolution process.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Formal study dispute... PROCESS § 5.14 Formal study dispute resolution process. (a) Within 20 days of the Study Plan Determination... under section 401 of the Clean Water Act, 42 U.S.C. 1341, may file a notice of study dispute with...

18 CFR 141.14 - Form No. 80, Licensed Hydropower Development Recreation Report.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Form No. 80, Licensed Hydropower Development Recreation Report. 141.14 Section 141.14 Conservation of Power and Water Resources... Hydropower Development Recreation Report. The form of the report, Licensed Hydropower Development Recreation...

Thinking with the saint: the miracle of Saint Januarius of Naples and science in early modern Europe.

PubMed

de Ceglia, Francesco Paolo

2014-01-01

The aim of this paper is to reconstruct the way in which early modem science questioned and indirectly influenced (while being in its turn influenced by) the conceptualization of the liquefaction of the blood of Saint Januarius, a phenomenon that has been taking place at regular intervals in Naples since the late Middle Ages. In the seventeenth century, a debate arose that divided Europe between supporters of a theory of divine intervention and believers in the occult properties of the blood. These two theoretical options reflected two different perspectives on the relationship between the natural and the supernatural. While in the seventeenth century, the emphasis was placed on the predictable periodicity of the miraculous event of liquefaction as a manifestation of God in his role as a divine regulator, in the eighteenth century the event came to be described as capricious and unpredictable, in an attempt to differentiate miracles from the workings of nature, which were deemed to be normative. The miracle of the blood of Saint Januarius thus provides a window through which we can catch a glimpse of how the natural order was perceived in early modern Europe at a time when the Continent was culturally fragmented into north and south, Protestantism and Catholicism, learned and ignorant.

Virological Surveillance of Dengue in Saint Martin and Saint Barthélemy, French West Indies, Using Blood Samples on Filter Paper

PubMed Central

Matheus, Séverine; Chappert, Jean-Loup; Cassadou, Sylvie; Berger, Franck; Labeau, Bhetty; Bremand, Laetitia; Winicki, Alain; Huc-Anais, Patricia; Quenel, Philippe; Dussart, Philippe

2012-01-01

To strengthen active dengue surveillance in Saint Martin and Saint Barthélemy, two French Caribbean islands, we evaluated the epidemiological usefulness of collecting blood samples from NS1-positive dengue patients on filter paper to identify the dengue serotypes circulating in these regions during a 27-month period. This approach allowed dengue serotypes to be identified by reverse transcriptase-polymerase chain reaction in 90.1% of the total set of 666 samples analyzed and, in 95.5% of the samples collected during the acute phase of the disease. This prospective virological surveillance using blood samples absorbed onto filter paper, which were stored at 4°C and shipped at ambient temperature to a specialized laboratory for analysis, allowed us to avoid the logistic and financial costs associated with shipping frozen venous blood samples. This surveillance system offers a low-cost alternative for reinforcing dengue prevention in areas where specialized laboratories do not exist, notably by facilitating the early detection of potentially new dengue serotypes. PMID:22232467

Saint Louis Center for Sustainment of Trauma and Readiness Skills: A Collaborative Air Force-Civilian Trauma Skills Training Program

DTIC Science & Technology

2016-05-19

NUMBER 6. AUTHOR(S) Jason W. Grimm , Karen Johnson 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION...ABSTRACT SAR 18. NUMBER OF PAGES 5 19a. NAME OF RESPONSIBLE PERSON Jason Grimm a. REPORT U b. ABSTRACT U c. THIS PAGE U 19b... Grimm Karen Johns For correspo Vista at Gra J Emerg Nu 0099-1767 Published b http://dx.do ■ ■ • ■SAINT LOUIS CENTER FOR SUSTAINMENT OF TRAUMA AND

14. INTERIOR OF 1903 POWERHOUSE SHOWING TURBINEGENERATOR UNIT NO. 18, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. INTERIOR OF 1903 POWERHOUSE SHOWING TURBINE-GENERATOR UNIT NO. 18, MANUFACTURED BY GENERAL ELECTRIC IN 1949 AND RATED AT 150 MEGAWATTS. IT WAS RETIRED FROM SERVICE SEVERAL YEARS AGO. - Commonwealth Electric Company, Fisk Street Electrical Generating Station, 1111 West Cermak Avenue, Chicago, Cook County, IL

14. Photocopy of pre1956 photograph. Original in library of John ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. Photocopy of pre-1956 photograph. Original in library of John S. Lehmann Building, Missouri Botanical Garden. CEILING, SHOWING ORIGINAL SKYLIGHT NOW PLASTERED OVER - Missouri Botanical Garden, Museum, 2345 Tower Grove Avenue, Saint Louis, Independent City, MO

A Report on the International Symposium on Nuclear Quadrupole Resonance Spectroscopy (5th) Held at the Laboratoire de Chimie du Coordination du CNRS, Toulouse, France, 10-14 September 1979,

DTIC Science & Technology

1980-09-03

has a rich cultural and academic heritage, being the site of one of the first universities in France . Today it is also the center of the French ...jPECTROSCOPY~iiLD A S.E COTATCEGANUB .C./Carter S. PERFORMING ORGANIZATION NAME AND ADDRESS I*. PROGRAM ELEMENT,, PROJECT . TASK ARE A a WORK UNIT NUNUERS...Resonance spectros- copy took place in Toulouse, France , Se?tember 10-14, 1979. Seven invited lectures and a selection from more than 50 contributed

Impact of bacteriophage Saint3 carriage on the immune evasion capacity and hemolytic potential of Staphylococcus aureus CC398.

PubMed

Jung, Philipp; Abdelbary, Mohamed M H; Kraushaar, Britta; Fetsch, Alexandra; Geisel, Jürgen; Herrmann, Mathias; Witte, Wolfgang; Cuny, Christiane; Bischoff, Markus

2017-02-01

Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) isolates of clonal complex 398 (CC398) are frequently found in Europe, and recent studies highlighted the importance of mobile genetic element (MGE) exchange for host adaptation of this lineage. Of note, one of the MGEs commonly found in human S. aureus isolates, the immune evasion cluster (IEC) harboring bacteriophage Saint3, is very rarely found in LA-MRSA CC398 isolates obtained from farm animals, but more frequently found in LA-MRSA CC398 that were retransmitted to humans. Here, we analyzed with a set of S. aureus CC398 isolates harboring/lacking φSaint3 how this MGE affects (i) phagocytosis of CC398 isolates by polymorphonuclear neutrophils (PMNs), and (ii) hemolysis of human and livestock-derived erythrocytes. Isolates lacking φSaint3 were more efficiently phagocytosed by human PMNs in whole blood phagocytosis assays than isolates harboring this bacteriophage, irrespective of their origin. Notably, a similar effect was observed when equine blood was utilized, but not detected with porcine blood. Integration of φSaint3 into LA-MRSA CC398 strains lacking this MGE confirmed these findings, as φSaint3-harboring recipients were again less efficiently ingested by PMNs in equine and human blood than their parental strains. Integration of φSaint3 strongly reduced the hemolytic potential of the culture supernatants against human-derived erythrocytes, and to a smaller extent also against porcine-derived erythrocytes, while φSaint3 integration only slightly affected the hemolytic capacities against equine-derived red blood cells. The significant protective effect of φSaint3 against phagocytosis by equine PMNs suggests that the host specificity of the IEC components might be broader than currently assumed. Copyright © 2016 Elsevier B.V. All rights reserved.

High Resolution Elevation Data for the Saint Louis River

EPA Science Inventory

Several data collections in the area of the Saint Louis River Estuary have recently become available. These include the Minnesota Elevation Mapping Project (MN Statewide LIDAR collect), South Shore LIDAR project (WI Collect), and NOAA’s bathymetric LIDAR. The EPA Mid-Continent ...

40 CFR 721.642 - Amines, N-(C14-18 and C16-16 unsaturated alkyl)] dipropylene-tri-, tripropylenetetra-, and...

Code of Federal Regulations, 2010 CFR

2010-07-01

... substances amines, N-(C14-18 and C16-18 unsaturated alkyl)] dipropylenetri-, (PMN P-94-1244... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Amines, N-(C14-18 and C16-16... Amines, N-(C14-18 and C16-16 unsaturated alkyl)] dipropylene-tri-, tripropylenetetra-, and...

76 FR 555 - Keystone Holdings, LLC and Compagnie de Saint-Gobain; Analysis of Proposed Agreement Containing...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-05

... relating to the manufacture and sale of alumina wear tiles. To resolve the competitive concerns raised by... exclude Saint-Gobain's North American alumina wear tile business operated out of a facility in Latrobe... tile business in Latrobe or certain other assets owned or controlled by Saint-Gobain relating to the...

14. Interior view, grain tanks (bins). Barrel view of tunnel ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. Interior view, grain tanks (bins). Barrel view of tunnel for load-out belt conveyor system located below tanks. Square, numbered spouts gravity-feed grain from overhead bins onto belt. - Saint Anthony Elevator No. 3, 620 Malcom Avenue, Southeast, Minneapolis, Hennepin County, MN

Geologic map of Saint Lawrence Island, Alaska

USGS Publications Warehouse

Patton, William W.; Wilson, Frederic H.; Taylor, Theresa A.

2011-01-01

Saint Lawrence Island is located in the northern Bering Sea, 190 km southwest of the tip of the Seward Peninsula, Alaska, and 75 km southeast of the Chukotsk Peninsula, Russia (see index map, map sheet). It lies on a broad, shallow-water continental shelf that extends from western Alaska to northeastern Russia. The island is situated on a northwest-trending structural uplift exposing rocks as old as Paleozoic above sea level. The submerged shelf between the Seward Peninsula and Saint Lawrence Island is covered mainly with Cenozoic deposits (Dundo and Egiazarov, 1982). Northeast of the island, the shelf is underlain by a large structural depression, the Norton Basin, which contains as much as 6.5 km of Cenozoic strata (Grim and McManus, 1970; Fisher and others, 1982). Sparse test-well data indicate that the Cenozoic strata are underlain by Paleozoic and Proterozoic rocks, similar to those exposed on the Seward Peninsula (Turner and others, 1983). Saint Lawrence Island is 160 km long in an east-west direction and from 15 km to 55 km wide in a north-south direction. The east end of the island consists largely of a wave-cut platform, which has been elevated as much as 30 m above sea level. Isolated upland areas composed largely of granitic plutons rise as much as 550 m above the wave-cut platform. The central part of the island is dominated by the Kookooligit Mountains, a large Quaternary shield volcano that extends over an area of 850 km2 and rises to an elevation of 630 m. The west end of the island is composed of the Poovoot Range, a group of barren, rubble-covered hills as high as 450 m that extend from Boxer Bay on the southwest coast to Taphook Mountain on the north coast. The Poovoot Range is flanked on the southeast by the Putgut Plateau, a nearly flat, lake-dotted plain that stands 30?60 m above sea level. The west end of the island is marked by uplands underlain by the Sevuokuk pluton (unit Kg), a long narrow granite body that extends from Gambell on the

The International Law Program at Saint Louis University.

ERIC Educational Resources Information Center

Dore, Isaak

1996-01-01

Saint Louis University (Missouri) has designed an international law curriculum to inculcate in students the idea that the Kantian notion of nations naturally united by mutual self-interest is truer today than ever, to expose students to the challenges of globalization in preparation for decision-making, and to equip them with intellectual tools to…

Understanding Latter-Day Saints Education: Principles and Resources

ERIC Educational Resources Information Center

Morgan, Barbara

2014-01-01

Using historic documents of the Church of Jesus Christ of Latter-day Saints (LDS) and resources of its leaders, the principles of LDS or Mormon education and its key characteristics are described. In particular, the following characteristics are discussed: (1) the critical role of the Spirit in both teaching and learning, (2) the worthiness,…

Middle Pleistocene Human Remains from Tourville-la-Rivière (Normandy, France) and Their Archaeological Context

PubMed Central

Faivre, Jean-Philippe; Maureille, Bruno; Bayle, Priscilla; Crevecoeur, Isabelle; Duval, Mathieu; Grün, Rainer; Bemilli, Céline; Bonilauri, Stéphanie; Coutard, Sylvie; Bessou, Maryelle; Limondin-Lozouet, Nicole; Cottard, Antoine; Deshayes, Thierry; Douillard, Aurélie; Henaff, Xavier; Pautret-Homerville, Caroline; Kinsley, Les; Trinkaus, Erik

2014-01-01

Despite numerous sites of great antiquity having been excavated since the end of the 19th century, Middle Pleistocene human fossils are still extremely rare in northwestern Europe. Apart from the two partial crania from Biache-Saint-Vaast in northern France, all known human fossils from this period have been found from ten sites in either Germany or England. Here we report the discovery of three long bones from the same left upper limb discovered at the open-air site of Tourville-la-Rivière in the Seine Valley of northern France. New U-series and combined US-ESR dating on animal teeth produced an age range for the site of 183 to 236 ka. In combination with paleoecological indicators, they indicate an age toward the end of MIS 7. The human remains from Tourville-la-Rivière are attributable to the Neandertal lineage based on morphological and metric analyses. An abnormal crest on the left humerus represents a deltoid muscle enthesis. Micro- and or macro-traumas connected to repetitive movements similar to those documented for professional throwing athletes could be origin of abnormality. PMID:25295956

France: Factors Shaping Foreign Policy, and Issues in U.S.-French Relations

DTIC Science & Technology

2009-05-20

TYPE 3. DATES COVERED 00-00-2009 to 00-00-2009 4. TITLE AND SUBTITLE France : Factors Shaping Foreign Policy, and Issues in U.S.- French ...Z39-18 France : Factors Shaping Foreign Policy, and Issues in U.S.- French Relations Congressional Research Service Summary The factors that shape... French foreign policy have changed since the end of the Cold War. The perspectives of France and the United States have diverged in some cases. More

Classification and Counter-Classification of Language on Saint Barthelemy.

ERIC Educational Resources Information Center

Pressman, Jon F.

1998-01-01

Analyzes the use of metapragmatic description in the ethnoclassification of language by native speakers on the Franco-Antillean island of Saint Barthelemy. A prevalent technique for metapragmatic description based on honorific pronouns that reflects the varied geolinguistic and generational attributes of the speakers is described. (Author/MSE)

75 FR 23589 - Safety Zones; Blasting Operations and Movement of Explosives, St. Marys River, Sault Sainte Marie...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-04

... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket No. USCG-2010-0290] RIN 1625-AA00 Safety Zones; Blasting Operations and Movement of Explosives, St. Marys River, Sault Sainte Marie... Movement of Explosives, St. Marys River, Sault Sainte Marie, MI. (a) Location. The following areas are...

Analogies between Kirchhoff plates and functionally graded Saint-Venant beams under torsion

NASA Astrophysics Data System (ADS)

Barretta, Raffaele; Luciano, Raimondo

2015-05-01

Exact solutions of elastic Kirchhoff plates are available only for special geometries, loadings and kinematic boundary constraints. An effective solution procedure, based on an analogy between functionally graded orthotropic Saint-Venant beams under torsion and inhomogeneous isotropic Kirchhoff plates, with no kinematic boundary constraints, is proposed. The result extends the one contributed in Barretta (Acta Mech 224(12):2955-2964, 2013) for the special case of homogeneous Saint-Venant beams under torsion. Closed-form solutions for displacement, bending-twisting moment and curvature fields of an elliptic plate, corresponding to a functionally graded orthotropic beam, are evaluated. A new benchmark for computational mechanics is thus provided.

DOE Office of Scientific and Technical Information (OSTI.GOV)

This profile provides a snapshot of the energy landscape of the northeast Caribbean island Saint Martin. The island is divided between two nations, France in the north (Saint-Martin) and the Netherlands in the south (Sint Maarten).

14 CFR 385.18 - Authority of the Chief, Coordination Section, Documentary Services Division.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Authority of the Chief, Coordination Section, Documentary Services Division. 385.18 Section 385.18 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ORGANIZATION STAFF ASSIGNMENTS AND REVIEW OF ACTION UNDER ASSIGNMENTS Assignment of Functions...

14 CFR 385.18 - Authority of the Chief, Coordination Section, Documentary Services Division.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Authority of the Chief, Coordination Section, Documentary Services Division. 385.18 Section 385.18 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ORGANIZATION STAFF ASSIGNMENTS AND REVIEW OF ACTION UNDER ASSIGNMENTS Assignment of Functions...

14 CFR 385.18 - Authority of the Chief, Coordination Section, Documentary Services Division.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Authority of the Chief, Coordination Section, Documentary Services Division. 385.18 Section 385.18 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ORGANIZATION STAFF ASSIGNMENTS AND REVIEW OF ACTION UNDER ASSIGNMENTS Assignment of Functions...

14 CFR 385.18 - Authority of the Chief, Coordination Section, Documentary Services Division.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Authority of the Chief, Coordination Section, Documentary Services Division. 385.18 Section 385.18 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ORGANIZATION STAFF ASSIGNMENTS AND REVIEW OF ACTION UNDER ASSIGNMENTS Assignment of Functions...

14 CFR 385.18 - Authority of the Chief, Coordination Section, Documentary Services Division.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Authority of the Chief, Coordination Section, Documentary Services Division. 385.18 Section 385.18 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ORGANIZATION STAFF ASSIGNMENTS AND REVIEW OF ACTION UNDER ASSIGNMENTS Assignment of Functions...

Impact of social and economic characteristics on orthodontic treatment among children and teenagers in France.

PubMed

Germa, A; Kaminski, M; Nabet, C

2010-04-01

This study aimed to estimate the prevalence of orthodontic treatment in France among children and teenagers aged 8-18 years, by sex and by age, and to investigate the specific role of social and economic characteristics on use of orthodontic treatment. We analyzed data from the cross-sectional national health survey conducted in France in 2002-2003, which included a sample of 5988 children aged 8-18 years. All data were collected by interview including the question on orthodontic treatment. Other data used in our study were family social status and income, maternal educational attainment and place of birth, whether the child was covered by a supplementary health insurance and whether the residence was urban or rural. We also calculated the density of orthodontists in the district. Multivariate logistic regression analyses were used to study the relationships between these social and economic factors and orthodontic treatment. The prevalence of orthodontic treatment was 14% of all children aged 8-18, 15% for girls, and 13% for boys, and 23% in the 12 to 15-year age group. Children were less likely to have orthodontic treatment when parents were service or sales workers compared with children whose parents were managers or professionals (aOR = 0.50; 95%CI: [0.34;0.76]), when family income was in the lowest, compared with highest quartile (aOR = 0,62; 95% CI: [0.45;0.85]), when children had no supplementary insurance compared with children covered by private insurance (aOR = 0.53; 95% CI: [0.34; 0.81]), or when they lived in rural compared with urban areas (aOR = 0.70; 95% CI: [0.54; 0.91]). There are social inequalities in orthodontic treatment in France, associated mainly with social status, annual income, supplementary insurance, and the residence area.

The Segmented Aperture Interferometric Nulling Testbed (SAINT) I: overview and air-side system description

NASA Astrophysics Data System (ADS)

Hicks, Brian A.; Lyon, Richard G.; Petrone, Peter; Ballard, Marlin; Bolcar, Matthew R.; Bolognese, Jeff; Clampin, Mark; Dogoda, Peter; Dworzanski, Daniel; Helmbrecht, Michael A.; Koca, Corina; Shiri, Ron

2016-07-01

This work presents an overview of the Segmented Aperture Interferometric Nulling Testbed (SAINT), a project that will pair an actively-controlled macro-scale segmented mirror with the Visible Nulling Coronagraph (VNC). SAINT will incorporate the VNC's demonstrated wavefront sensing and control system to refine and quantify end-to-end high-contrast starlight suppression performance. This pathfinder testbed will be used as a tool to study and refine approaches to mitigating instabilities and complex diffraction expected from future large segmented aperture telescopes.

The Segmented Aperture Interferometric Nulling Testbed (SAINT) I: Overview and Air-side System Description

NASA Technical Reports Server (NTRS)

Hicks, Brian A.; Lyon, Richard G.; Petrone, Peter, III; Bolcar, Matthew R.; Bolognese, Jeff; Clampin, Mark; Dogoda, Peter; Dworzanski, Daniel; Helmbrecht, Michael A.; Koca, Corina;

Prospecting Anticancer Compounds in Actinomycetes Recovered from the Sediments of Saint Peter and Saint Paul's Archipelago, Brazil.

PubMed

Ferreira, Elthon G; Torres, Maria da Conceição M; da Silva, Alison B; Colares, Larissa L F; Pires, Karine; Lotufo, Tito M C; Silveira, Edilberto R; Pessoa, Otília D L; Costa-Lotufo, Leticia V; Jimenez, Paula C

2016-09-01

Saint Peter and Saint Paul's Archipelago is a collection of 15 islets and rocks remotely located in the equatorial Atlantic Ocean. In this particular site, the present project intended to assess the biodiversity and biotechnological potential of bacteria from the actinomycete group. This study presents the first results of this assessment. From 21 sediment samples, 268 strains were isolated and codified as BRA followed by three numbers. Of those, 94 strains were grown in liquid media and submitted to chemical extractions with AcOEt (A), BuOH (B), and MeOH (M). A total of 224 extracts were screened for their cytotoxic activity and 41 were significantly active against HCT-116 cancer cells. The obtained IC 50 values ranged from 0.04 to 31.55 μg/ml. The HR-LC/MS dereplication analysis of the active extracts showed the occurrence of several known anticancer compounds. Individual compounds, identified using HR-MS combined with analysis of the AntiMarin database, included saliniketals A and B, piericidins A and C and glucopiericidin A, staurosporine, N-methylstaurosporine, hydroxydimethyl-staurosporine and N-carbamoylstaurosporine, salinisporamycin A, and rifamycins S and B. BRA-199, identified as Streptomyces sp., was submitted to bioassay-guided fractionation, leading to isolation of the bioactive piericidins A and C, glucopiericidin, and three known diketopiperazines, cyclo(l-Phe-trans-4-OH-l-Pro), cyclo(l-Phe-l-Pro), and cyclo(l-Trp-l-Pro). © 2016 Wiley-VHCA AG, Zürich.

Pathology and the posture of the La Chapelle-aux-Saints Neandertal.

PubMed

Trinkaus, E

1985-05-01

The depiction of the Neandertals as incompletely erect was based primarily on Boule's (1911, 1912a, 1913) analysis of the La Chapelle-aux-Saints 1 partial skeleton. The inaccurate aspects of Boule's postural reconstruction were corrected during the 1950s. However, it has come to be believed, following Straus and Cave (1957), that Boule's errors of reconstruction were due to the diseased condition of the La Chapelle-aux-Saints 1 remains, rather than to Boule's misinterpretation of morphology. The abnormalities on the La Chapelle-aux-Saints 1 postcranium include: lower cervical, upper thoracic, and lower thoracic intervertebral degenerative joint disease (DJD), a distal fracture of a mid-thoracic rib, extensive DJD of the left hip, DJD of the right fifth proximal interphalangeal articulation, bilateral humeral head eburnation, and minor exostosis formation on the right humerus, ulna, and radius. These were associated with extensive alveolar inflammation including apical abscesses and antemortem tooth loss, some temporomandibular DJD, bilateral auditory exostoses, and minimal occipital condyle DJD. None of these abnormalities significantly affected Boule's Neandertal postural reconstruction, and a review of his analysis indicates that early twentieth century interpretations of skeletal morphology (primarily of the cranium, cervical vertebrae, lumbar and sacral vertebrae, proximal femora and tibiae, posterior tarsals, and hallucial tarsometatarsal joint), combined with Boule's evolutionary preconceptions, were responsible for his mistaken view of Neandertal posture.

SRTM Stereo Pair with Landsat Overlay: Miquelon and Saint Pierre Islands

NASA Image and Video Library

2000-10-20

This stereoscopic satellite image showing Miquelon and Saint Pierre Islands, located south of Newfoundland, Canada, was generated by draping NASA Landsat satellite image over a preliminary Shuttle Radar Topography Mission SRTM elevation model.

Evaluating the Effectiveness of France's Indoor Smoke-Free Law 1 Year and 5 Years after Implementation: Findings from the ITC France Survey.

PubMed

Fong, Geoffrey T; Craig, Lorraine V; Guignard, Romain; Nagelhout, Gera E; Tait, Megan K; Driezen, Pete; Kennedy, Ryan David; Boudreau, Christian; Wilquin, Jean-Louis; Deutsch, Antoine; Beck, François

2013-01-01

France implemented a comprehensive smoke-free law in two phases: Phase 1 (February 2007) banned smoking in workplaces, shopping centres, airports, train stations, hospitals, and schools; Phase 2 (January 2008) banned smoking in hospitality venues (bars, restaurants, hotels, casinos, nightclubs). This paper evaluates France's smoke-free law based on the International Tobacco Control Policy Evaluation Project in France (the ITC France Project), which conducted a cohort survey of approximately 1,500 smokers and 500 non-smokers before the implementation of the laws (Wave 1) and two waves after the implementation (Waves 2 and 3). Results show that the smoke-free law led to a very significant and near-total elimination of observed smoking in key venues such as bars (from 94-97% to 4%) and restaurants (from 60-71% to 2-3%) at Wave 2, which was sustained four years later (6-8% in bars; 1-2% in restaurants). The reduction in self-reported smoking by smoking respondents was nearly identical to the effects shown in observed smoking. Observed smoking in workplaces declined significantly after the law (from 41-48% to 18-20%), which continued to decline at Wave 3 (to 14-15%). Support for the smoke-free laws increased significantly after their implementation and continued to increase at Wave 3 (p<.001 among smokers for bars and restaurants; p<.001 among smokers and p = .003 for non-smokers for workplaces). The findings demonstrate that smoke-free policies that are implemented in ways consistent with the Guidelines for Article 8 of the WHO Framework Convention on Tobacco Control (WHO FCTC) lead to substantial and sustained reductions in indoor smoking while also leading to high levels of support by the public. Moreover, contrary to arguments by opponents of smoke-free laws, smoking in the home did not increase after the law was implemented and prevalence of smoke-free homes among smokers increased from 23.2% before the law to 37.2% 5 years after the law.

Epidemiology of invasive Streptococcus pyogenes infections in France in 2007.

PubMed

Lepoutre, A; Doloy, A; Bidet, P; Leblond, A; Perrocheau, A; Bingen, E; Trieu-Cuot, P; Bouvet, A; Poyart, C; Lévy-Bruhl, D

2011-12-01

Invasive group A streptococcal (GAS) infections cause significant morbidity and mortality. A national survey was initiated to assess the burden of invasive GAS infections in France, describe their clinical characteristics, and assess the molecular characteristics of GAS strains responsible for these infections. The survey was conducted in 194 hospitals, accounting for 51% of acute care hospital admissions in France. Clinical data, predisposing factors, and demographic data were obtained, and all GAS isolates were emm sequence typed. We identified 664 cases of invasive GAS infections, with an annual incidence of 3.1 per 100,000 population. The case-fatality ratio was 14% and rose to 43% in the case of streptococcal toxic shock syndrome. Bacteremia without identified focus (22%) and skin/soft tissue infections (30%) were the most frequent clinical presentations. Necrotizing fasciitis was frequent in adults (18%) and uncommon in children (3%). The 3 predominant emm types were emm1, emm89, and emm28, accounting for 33%, 16%, and 10% of GAS isolates, respectively. The emm1 type was associated with fatal outcomes and was more frequent in children than in adults. Six clusters of cases were identified, with each cluster involving 2 invasive cases due to GAS strains which shared identical GAS emm sequence types. Four clusters of cases involved eight postpartum infections, one family cluster involved a mother and child, and one cluster involved two patients in a nursing home. Invasive GAS infection is one of the most severe bacterial diseases in France, particularly in persons aged ≥ 50 years or when associated with toxic shock syndrome.

Intersections et Convergence

DTIC Science & Technology

2000-01-01

Malo, France , 1-7 July 1999. Proceedings, Volume 1. Curve and Surface Design To order the complete compilation report, use: ADA399461 The component...trie projective , tr~is efficace; malheureusement, tous mes efforts de 1𔄀tendre hi d’autres valeurs de n oat 6chou6. J’ajouterai h l’adresse des...verticale, qui coupe la forme en trois points, int~rieurs an carreau consid~r6. Comment l’usinerait-on ? Comment l’embontir ? Paul de Faget de Casteijan 4 Avenue du Commerce 78000 Versailles, France

Diet and behavior of the Saint-Césaire Neanderthal inferred from biogeochemical data inversion.

PubMed

Balter, Vincent; Simon, Laurent

2006-10-01

Biogeochemistry is a powerful tool for dietary reconstruction, and mixing equations can be used to quantify the contribution of multiple sources to an individual's diet. The goals of this paper are: 1) to generalize the inverse method to dietary mixtures; and 2) to reconstruct the diet of the Saint-Césaire Neanderthal using Sr/Ca and Ba/Ca data of the mineral fraction of bone (hydroxylapatite), and with published delta13C and delta15N data of the associated organic fraction of bone (collagen). A new method is proposed to calculate the maximum diagenetic contribution of the Sr/Ba ratio, assuming that the soil soluble fraction is the diagenetic end-member and, for a given fraction of diagenesis, allows the restoration of the original Sr/Ba ratio. Considering the Saint-Césaire Châtelperronian mammalian assemblage as the meat source, and on the basis of available Sr, Ba, and Ca contents of plants, the results indicate that the percentage of plants in the Neanderthal's diet must have been close to zero for realistic Sr and Ba impoverishment between diet and hydroxylapatite. Contrary to previous studies, it is shown that fish could constitute a significant proportion (30%) of the diet of the Saint-Césaire Neanderthal. However, this mass balance solution is not supported by the zooarchaeological data. When the entire faunal assemblage is considered as the dietary source, the calculation shows that bovids (except reindeer) represent the greatest percentage of consumed meat (58%), followed by horses/rhinoceros (22%), reindeer (13%), and mammoths (7%). These respective percentages are in close accordance with zooarchaeological records, suggesting that the faunal assemblage associated with the Neanderthal of Saint-Césaire reliably reflects what he ate during the last few years of his life. In behavioral terms, this result supports the hypothesis that this Neanderthal carried the foodstuffs back to the Saint-Césaire shelter before their consumption.

33 CFR 165.763 - Moving and Fixed Security Zone, Port of Fredericksted, Saint Croix, U.S. Virgin Islands.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Saint Croix, U.S. Virgin Islands. (a) Location. A moving and fixed security zone is established that surrounds all cruise ships entering, departing, mooring or anchoring in the Port of Fredericksted, Saint Croix, U.S. Virgin Islands. The security zone extends from the cruise ship outward and forms a 50-yard...

33 CFR 165.763 - Moving and Fixed Security Zone, Port of Fredericksted, Saint Croix, U.S. Virgin Islands.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., Saint Croix, U.S. Virgin Islands. (a) Location. A moving and fixed security zone is established that surrounds all cruise ships entering, departing, mooring or anchoring in the Port of Fredericksted, Saint Croix, U.S. Virgin Islands. The security zone extends from the cruise ship outward and forms a 50-yard...

33 CFR 165.763 - Moving and Fixed Security Zone, Port of Fredericksted, Saint Croix, U.S. Virgin Islands.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., Saint Croix, U.S. Virgin Islands. (a) Location. A moving and fixed security zone is established that surrounds all cruise ships entering, departing, mooring or anchoring in the Port of Fredericksted, Saint Croix, U.S. Virgin Islands. The security zone extends from the cruise ship outward and forms a 50-yard...

33 CFR 165.763 - Moving and Fixed Security Zone, Port of Fredericksted, Saint Croix, U.S. Virgin Islands.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., Saint Croix, U.S. Virgin Islands. (a) Location. A moving and fixed security zone is established that surrounds all cruise ships entering, departing, mooring or anchoring in the Port of Fredericksted, Saint Croix, U.S. Virgin Islands. The security zone extends from the cruise ship outward and forms a 50-yard...

33 CFR 165.763 - Moving and Fixed Security Zone, Port of Fredericksted, Saint Croix, U.S. Virgin Islands.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., Saint Croix, U.S. Virgin Islands. (a) Location. A moving and fixed security zone is established that surrounds all cruise ships entering, departing, mooring or anchoring in the Port of Fredericksted, Saint Croix, U.S. Virgin Islands. The security zone extends from the cruise ship outward and forms a 50-yard...

Mapping and predictive variations of soil bacterial richness across France.

PubMed

Terrat, Sébastien; Horrigue, Walid; Dequiedt, Samuel; Saby, Nicolas P A; Lelièvre, Mélanie; Nowak, Virginie; Tripied, Julie; Régnier, Tiffanie; Jolivet, Claudy; Arrouays, Dominique; Wincker, Patrick; Cruaud, Corinne; Karimi, Battle; Bispo, Antonio; Maron, Pierre Alain; Chemidlin Prévost-Bouré, Nicolas; Ranjard, Lionel

2017-01-01

Although numerous studies have demonstrated the key role of bacterial diversity in soil functions and ecosystem services, little is known about the variations and determinants of such diversity on a nationwide scale. The overall objectives of this study were i) to describe the bacterial taxonomic richness variations across France, ii) to identify the ecological processes (i.e. selection by the environment and dispersal limitation) influencing this distribution, and iii) to develop a statistical predictive model of soil bacterial richness. We used the French Soil Quality Monitoring Network (RMQS), which covers all of France with 2,173 sites. The soil bacterial richness (i.e. OTU number) was determined by pyrosequencing 16S rRNA genes and related to the soil characteristics, climatic conditions, geomorphology, land use and space. Mapping of bacterial richness revealed a heterogeneous spatial distribution, structured into patches of about 111km, where the main drivers were the soil physico-chemical properties (18% of explained variance), the spatial descriptors (5.25%, 1.89% and 1.02% for the fine, medium and coarse scales, respectively), and the land use (1.4%). Based on these drivers, a predictive model was developed, which allows a good prediction of the bacterial richness (R2adj of 0.56) and provides a reference value for a given pedoclimatic condition.

CD14 and IL18 gene polymorphisms associated with colorectal cancer subsite risks among atomic bomb survivors.

PubMed

Hu, Yiqun; Yoshida, Kengo; Cologne, John B; Maki, Mayumi; Morishita, Yukari; Sasaki, Keiko; Hayashi, Ikue; Ohishi, Waka; Hida, Ayumi; Kyoizumi, Seishi; Kusunoki, Yoichiro; Tokunaga, Katsushi; Nakachi, Kei; Hayashi, Tomonori

2015-01-01

Colorectal cancer (CRC) is a common malignancy worldwide, and chronic inflammation is a risk factor for CRC. In this study, we carried out a cohort study among the Japanese atomic bomb (A-bomb) survivor population to investigate any association between immune- and inflammation-related gene polymorphisms and CRC. We examined the effects of six single-nucleotide polymorphisms of CD14 and IL18 on relative risks (RRs) of CRC. Results showed that RRs of CRC, overall and by anatomic subsite, significantly increased with increasing radiation dose. The CD14-911A/A genotype showed statistically significant higher risks for all CRC and distal CRC compared with the other two genotypes. In addition, the IL18-137 G/G genotype showed statistically significant higher risks for proximal colon cancer compared with the other two genotypes. In phenotype-genotype analyses, the CD14-911A/A genotype presented significantly higher levels of membrane and soluble CD14 compared with the other two genotypes, and the IL18-137 G/G genotype tended to be lower levels of plasma interleukin (IL)-18 compared with the other two genotypes. These results suggest the potential involvement of a CD14-mediated inflammatory response in the development of distal CRC and an IL18-mediated inflammatory response in the development of proximal colon cancer among A-bomb survivors.

CD14 and IL18 gene polymorphisms associated with colorectal cancer subsite risks among atomic bomb survivors

PubMed Central

Hu, Yiqun; Yoshida, Kengo; Cologne, John B; Maki, Mayumi; Morishita, Yukari; Sasaki, Keiko; Hayashi, Ikue; Ohishi, Waka; Hida, Ayumi; Kyoizumi, Seishi; Kusunoki, Yoichiro; Tokunaga, Katsushi; Nakachi, Kei; Hayashi, Tomonori

2015-01-01

Colorectal cancer (CRC) is a common malignancy worldwide, and chronic inflammation is a risk factor for CRC. In this study, we carried out a cohort study among the Japanese atomic bomb (A-bomb) survivor population to investigate any association between immune- and inflammation-related gene polymorphisms and CRC. We examined the effects of six single-nucleotide polymorphisms of CD14 and IL18 on relative risks (RRs) of CRC. Results showed that RRs of CRC, overall and by anatomic subsite, significantly increased with increasing radiation dose. The CD14–911A/A genotype showed statistically significant higher risks for all CRC and distal CRC compared with the other two genotypes. In addition, the IL18–137 G/G genotype showed statistically significant higher risks for proximal colon cancer compared with the other two genotypes. In phenotype–genotype analyses, the CD14–911A/A genotype presented significantly higher levels of membrane and soluble CD14 compared with the other two genotypes, and the IL18–137 G/G genotype tended to be lower levels of plasma interleukin (IL)-18 compared with the other two genotypes. These results suggest the potential involvement of a CD14-mediated inflammatory response in the development of distal CRC and an IL18-mediated inflammatory response in the development of proximal colon cancer among A-bomb survivors. PMID:27081544

40 CFR 721.10395 - Fatty acids, C14-18 and C16-18 unsatd., polymers with adipic acid and triethanolamine, di-Me...

Code of Federal Regulations, 2012 CFR

2012-07-01

...., polymers with adipic acid and triethanolamine, di-Me sulfate-quaternized. 721.10395 Section 721.10395... Fatty acids, C14-18 and C16-18 unsatd., polymers with adipic acid and triethanolamine, di-Me sulfate... sulfate-quaternized (PMN P-10-458; CAS No. 1211825-32-9) is subject to reporting under this section for...

40 CFR 721.10395 - Fatty acids, C14-18 and C16-18 unsatd., polymers with adipic acid and triethanolamine, di-Me...

Code of Federal Regulations, 2013 CFR

2013-07-01

...., polymers with adipic acid and triethanolamine, di-Me sulfate-quaternized. 721.10395 Section 721.10395... Fatty acids, C14-18 and C16-18 unsatd., polymers with adipic acid and triethanolamine, di-Me sulfate... sulfate-quaternized (PMN P-10-458; CAS No. 1211825-32-9) is subject to reporting under this section for...

40 CFR 721.10395 - Fatty acids, C14-18 and C16-18 unsatd., polymers with adipic acid and triethanolamine, di-Me...

Code of Federal Regulations, 2014 CFR

2014-07-01

...., polymers with adipic acid and triethanolamine, di-Me sulfate-quaternized. 721.10395 Section 721.10395... Fatty acids, C14-18 and C16-18 unsatd., polymers with adipic acid and triethanolamine, di-Me sulfate... sulfate-quaternized (PMN P-10-458; CAS No. 1211825-32-9) is subject to reporting under this section for...

Deformation during terrane accretion in the Saint Elias orogen, Alaska

USGS Publications Warehouse

Bruhn, R.L.; Pavlis, T.L.; Plafker, G.; Serpa, L.

2004-01-01

The Saint Elias orogen of southern Alaska and adjacent Canada is a complex belt of mountains formed by collision and accretion of the Yakutat terrane into the transition zone from transform faulting to subduction in the northeast Pacific. The orogen is an active analog for tectonic processes that formed much of the North American Cordillera, and is also an important site to study (1) the relationships between climate and tectonics, and (2) structures that generate large- to great-magnitude earthquakes. The Yakutat terrane is a fragment of the North American plate margin that is partly subducted beneath and partly accreted to the continental margin of southern Alaska. Interaction between the Yakutat terrane and the North American and Pacific plates causes significant differences in the style of deformation within the terrane. Deformation in the eastern part of the terrane is caused by strike-slip faulting along the Fairweather transform fault and by reverse faulting beneath the coastal mountains, but there is little deformation immediately offshore. The central part of the orogen is marked by thrusting of the Yakutat terrane beneath the North American plate along the Chugach-Saint Elias fault and development of a wide, thin-skinned fold-and-thrust belt. Strike-slip faulting in this segment may he localized in the hanging wall of the Chugach-Saint Elias fault, or dissipated by thrust faulting beneath a north-northeast-trending belt of active deformation that cuts obliquely across the eastern end of the fold-and-thrust belt. Superimposed folds with complex shapes and plunging hinge lines accommodate horizontal shortening and extension in the western part of the orogen, where the sedimentary cover of the Yakutat terrane is accreted into the upper plate of the Aleutian subduction zone. These three structural segments are separated by transverse tectonic boundaries that cut across the Yakutat terrane and also coincide with the courses of piedmont glaciers that flow from

Epidemiology of Invasive Streptococcus pyogenes Infections in France in 2007 ▿

PubMed Central

Lepoutre, A.; Doloy, A.; Bidet, P.; Leblond, A.; Perrocheau, A.; Bingen, E.; Trieu-Cuot, P.; Bouvet, A.; Poyart, C.; Lévy-Bruhl, D.

2011-01-01

Invasive group A streptococcal (GAS) infections cause significant morbidity and mortality. A national survey was initiated to assess the burden of invasive GAS infections in France, describe their clinical characteristics, and assess the molecular characteristics of GAS strains responsible for these infections. The survey was conducted in 194 hospitals, accounting for 51% of acute care hospital admissions in France. Clinical data, predisposing factors, and demographic data were obtained, and all GAS isolates were emm sequence typed. We identified 664 cases of invasive GAS infections, with an annual incidence of 3.1 per 100,000 population. The case-fatality ratio was 14% and rose to 43% in the case of streptococcal toxic shock syndrome. Bacteremia without identified focus (22%) and skin/soft tissue infections (30%) were the most frequent clinical presentations. Necrotizing fasciitis was frequent in adults (18%) and uncommon in children (3%). The 3 predominant emm types were emm1, emm89, and emm28, accounting for 33%, 16%, and 10% of GAS isolates, respectively. The emm1 type was associated with fatal outcomes and was more frequent in children than in adults. Six clusters of cases were identified, with each cluster involving 2 invasive cases due to GAS strains which shared identical GAS emm sequence types. Four clusters of cases involved eight postpartum infections, one family cluster involved a mother and child, and one cluster involved two patients in a nursing home. Invasive GAS infection is one of the most severe bacterial diseases in France, particularly in persons aged ≥50 years or when associated with toxic shock syndrome. PMID:21976764

Operations in California during the Mexican American War

DTIC Science & Technology

2016-05-26

assertion that he was on private business. On December 10, 1845 he arrived at Vera Cruz and proceeded overland to Mexico City where the Paredes revolution...Majesty’s Ship “Collingwood” From 1844-1848 (Paris, France: E . Briére, rue Sainte-Anne, 1850), 162-163.The policy of non- interference toward...From 1844-1848. Paris, France: E . Briére, rue Sainte-Anne, 1850. Watson, Douglas S. “The First Mail Contract in California.” California Historical Quarterly 10, no. 4 (December 1931): 353-354.

Measuring Morale within the French Army

DTIC Science & Technology

2006-04-01

Measuring Morale within the French Army 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK...RTO-MP-HFM-134 29 - 1 Measuring Morale within the French Army Commandant Jean Michel FORET EMAT/Centre de Relations Humaines 14 rue Saint...Dominique 00453 Armées FRANCE crh.emat@emat.terre.defense.gouv.fr ABSTRACT The evaluation of the operational capabilitity of the Army passes by

[Saint-Jacques de Besançon Hospital].

PubMed

Deridder, Annick

2007-01-01

The first plan (1670) was carried out by Archbishop Antoine Pierre 1st de Grammont under the Spanish administration, with the aid of the Community Saint Marthe whose Congregation was at the start of a new monastic order and whose last members left Besançon a few years ago. At the beginning King Louis XIVth supported the building of the new hospital (1865) which was intended to shelter numerous soldiers like some other hospitals of the time. The main walls were ended in 1701 and the garden in 1702. The first patients were received in 1691. The cross-shaped Italian building is centred on a chapel and looks like many other buildings such as "La Salpêtriere" in Paris. It superseded the ancient medieval building "Saint-Jacques des Arènes" vowed to the travellers and pilgrims, the site of which was on the main crossing roads but on too small a space. The main architect was Canon Jacques Magnin, the material was found in the country and the gorgeous railings were forged by a local craftsman Chappuis. A local practitioner Gabriel Gascon bequeathed his sumptuous apothecary's shop. Some extensions of the building occured during the following centuries: a wing towards the garden, the "Couvent du Refuge" and its brilliant baroque chapel allowed the whole building to have a praise worthy chapel. At last the "Hôtel de Mont martin" initially built for Cardinal Granvelle was joined to the main hospital and became the Maternity Hospital.

Absence of t(14;18) chromosome translocation in agricultural workers after short-term exposure to pesticides.

PubMed

Rapisarda, Venerando; Ledda, Caterina; Matera, Serena; Fago, Lucrezia; Arrabito, Giorgio; Falzone, Luca; Marconi, Andrea; Libra, Massimo; Loreto, Carla

2017-05-01

Exposure to pesticides represents a potential health risk for the general population and for agricultural workers in particular. Some researchers observed that occupational exposure to pesticides is associated with risk of non‑Hodgkin's lymphoma (NHL). The chromosomal translocation t(14;18)(q32;q21) is one of the most common chromosomal abnormalities in NHL. The aim of this study was to detect the effects of pesticides on t(14;18) chromosome translocation in agricultural workers after short-term exposure. Fifty-two workers occupationally exposed to pesticides (fungicides and insecticides) and 52 non-exposed were recruited. The farm workers were on average exposed to pesticides for ~3.7 h a day for 5 years. The frequency of BCL2-IGH t(14;18) translocation in workers occupationally exposed to pesticides was 10% (5 of 52) vs. 8% (4 of 52) in the control group. Overall, these data suggest that no significant association between occupational exposure to pesticides and an increased frequency of the chromosomal translocation BCL2-IGH t(14;18) in farmers was observed. However, further studies with a higher number of subjects exposed to pesticides are necessary to confirm this observation.

Scripture-Based Discourses of Latter-Day Saint and Methodist Youths

ERIC Educational Resources Information Center

Rackley, Eric D.

2014-01-01

Drawing on social and cultural perspectives of literacy, conceptualizations of religious literacies, and Gee's notion of Discourses, I develop a framework for exploring 16 Latter-day Saint and Methodist youths' religious literacies as social and cultural practice. This work grows out of the increasingly important role that religion plays…

S-factor of 14 N (α, γ)18 F reaction at low-energies

NASA Astrophysics Data System (ADS)

Khalili, H.

2018-06-01

The astrophysical S-factor of the 14 N (α, γ)18 F reaction has been studied at range of bombarding energy 1-1.30 MeV. The 14 N (α, γ)18 F process is important in low energy astrophysics so that a possible source of energy in massive stars which have spent their hydrogen cycle. Using the Wood-saxon potential model, we have been calculated non resonances the astrophysical S-factors for the E 2 transition and our results for Eα = 0.0 MeV is S ≈ 0.5 MeV.b where from experimental is measured to Eα = 0.0 is S ≈ o . 7 MeV.b (Couch et al., 1971) that in comparison with our data good agreement is achieved for the astrophysical S-factor of this process.

Legislative Review. A Look at Higher Education in Week 10: March 14-18, 2011

ERIC Educational Resources Information Center

North Dakota University System, 2011

2011-01-01

This issue of "Legislative Review" takes a look at what's new in higher education from March 14-18, 2011. This Legislative Review reports that: (1) HB 1018, the Department of Commerce budget bill, was heard in Senate Appropriations March 15; (2) HB 1106 was heard in Senate Education March 14, received a 7-0 "do not pass"…

14 CFR 141.18 - Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances. 141.18 Section 141.18 Aeronautics and Space FEDERAL AVIATION... General § 141.18 Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances...

14 CFR 141.18 - Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances. 141.18 Section 141.18 Aeronautics and Space FEDERAL AVIATION... General § 141.18 Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances...

14 CFR 141.18 - Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances. 141.18 Section 141.18 Aeronautics and Space FEDERAL AVIATION... General § 141.18 Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances...

14 CFR 141.18 - Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances. 141.18 Section 141.18 Aeronautics and Space FEDERAL AVIATION... General § 141.18 Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances...

14 CFR 141.18 - Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances. 141.18 Section 141.18 Aeronautics and Space FEDERAL AVIATION... General § 141.18 Carriage of narcotic drugs, marijuana, and depressant or stimulant drugs or substances...

Exploitation of intertidal feeding resources by the red knot Calidris canutus under megatidal conditions (Bay of Saint-Brieuc, France)

NASA Astrophysics Data System (ADS)

Sturbois, Anthony; Ponsero, Alain; Desroy, Nicolas; Le Mao, Patrick; Fournier, Jérôme

2015-02-01

The feeding ecology of the red knot has been widely studied across its wintering range. Red knots mainly select bivalves and gastropods, with differences between sites due to variation in prey availability. The shorebird's diet is also influenced or controlled by the tidal regime. The aim of this paper is to demonstrate the adaptation of foraging red knots to the megatidal environment. The variation in their diet during tidal cycles was studied in the bay of Saint-Brieuc, a functional unit for this species. The method used combined macrofauna, distribution of foraging birds and diet data. Comparative spatial analyses of macrofauna and distribution of foraging red knots have shown that the bay's four benthic assemblages are exploited by birds. By analysing droppings, we highlighted that bivalve molluscs are the main component of their diet, as shown in most overwintering sites. Fifteen types of prey were identified and Donax vittatus was discovered to be a significant prey item. The relative proportion of each main prey item differs significantly depending on the benthic assemblage used to forage. All available benthic assemblages and all potential feeding resources can be used during a single tidal cycle, reflecting an adaptation to megatidal conditions. This approach develops accurate knowledge about the feeding ecology of birds which managers need in order to identify optimal areas for the conservation of waders based on the areas and resources actually used by the birds.

THE FREQUENCY OF T(14;18) IN BLOOD LYMPHOCYTES IS STABLE OVER A 2 YEAR PERIOD IN ADULTS

EPA Science Inventory

The Frequency of t(14;18) in Blood Lymphocytes Is Stable over a 2 Year Period in Adults

As part of a multi-endpoint molecular epidemiology study on in utero environmental exposures, umbilical cord and adult blood lymphocytes were examined for the frequency of t(14;18) by ...

Atypical aetiology of a conjugal fever: autochthonous airport malaria between Paris and French Riviera: a case report

PubMed Central

Pomares-Estran, Christelle; Delaunay, Pascal; Mottard, Annie; Cua, Eric; Roger, Pierre-Marie; Pradines, Bruno; Parzy, Daniel; Bogreau, Hervé; Rogier, Christophe; Jeannin, Charles; Karch, Saïd; Fontenille, Didier; Dejour-Salamanca, Dominique; Legros, Fabrice; Marty, Pierre

2009-01-01

Endemic malaria has been eradicated from France, but some falciparum malaria cases have been described in patients who have never travelled outside the country. Ms. V. 21 year-old and Mr. M. 23 year-old living together in Paris were on holiday in Saint Raphaël (French Riviera). They presented with fever, vertigo and nausea. A blood smear made to control thrombocytopaenia revealed intra-erythrocytic forms of Plasmodium falciparum. The parasitaemia level was 0.15% for Ms. V and 3.2% for Mr. M. This couple had no history of blood transfusion or intravenous drug use. They had never travelled outside metropolitan France, but had recently travelled around France: to Saint Mard (close to Paris Charles de Gaulle (CdG) airport), to Barneville plage (in Normandy) and finally to Saint Raphaël. The most probable hypothesis is an infection transmitted in Saint Mard by an imported anopheline mosquito at CdG airport. The DNA analysis of parasites from Ms. V.'s and Mr. M.'s blood revealed identical genotypes. Because it is unlikely that two different anopheline mosquitoes would be infected by exactly the same clones, the two infections must have been caused by the infective bites of the same infected mosquito. PMID:19698152

Trends and seasonality of river nutrients in agricultural catchments: 18years of weekly citizen science in France.

PubMed

Abbott, Benjamin W; Moatar, Florentina; Gauthier, Olivier; Fovet, Ophélie; Antoine, Virginie; Ragueneau, Olivier

2018-05-15

Agriculture and urbanization have disturbed three-quarters of global ice-free land surface, delivering huge amounts of nitrogen and phosphorus to freshwater ecosystems. These excess nutrients degrade habitat and threaten human food and water security at a global scale. Because most catchments are either currently subjected to, or recovering from anthropogenic nutrient loading, understanding the short- and long-term responses of river nutrients to changes in land use is essential for effective management. We analyzed a never-published, 18-year time series of anthropogenic (NO 3 - and PO 4 3- ) and naturally derived (dissolved silica) riverine nutrients in 13 catchments recovering from agricultural pollution in western France. In a citizen science initiative, high-school students sampled catchments weekly, which ranged from 26 to 1489km 2 . Nutrient concentrations decreased substantially over the period of record (19 to 50% for NO 3 - and 14 to 80% for PO 4 3- ), attributable to regional, national, and international investment and regulation, which started immediately prior to monitoring. For the majority of catchments, water quality during the summer low-flow period improved faster than during winter high-flow conditions, and annual minimum concentrations improved relatively faster than annual maximum concentrations. These patterns suggest that water-quality improvements were primarily due to elimination of discrete nutrient sources with seasonally-constant discharge (e.g. human and livestock wastewater), agreeing with available land-use and municipal records. Surprisingly, long-term nutrient decreases were not accompanied by changes in nutrient seasonality in most catchments, attributable to persistent, diffuse nutrient stocks. Despite decreases, nutrient concentrations in almost all catchments remained well above eutrophication thresholds, and because additional improvements will depend on decreasing diffuse nutrient sources, future gains may be much slower than

78 FR 23107 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-18

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2012-1087; Directorate Identifier 2009-SW-32-AD; Amendment 39-17424; AD 2013-08-07] RIN 2120-AA64...-07 Eurocopter France: Amendment 39-17424; Docket No. FAA- 2012-1087; Directorate Identifier 2009-SW...

Consistent initial conditions for the Saint-Venant equations in river network modeling

NASA Astrophysics Data System (ADS)

Yu, Cheng-Wei; Liu, Frank; Hodges, Ben R.

2017-09-01

Initial conditions for flows and depths (cross-sectional areas) throughout a river network are required for any time-marching (unsteady) solution of the one-dimensional (1-D) hydrodynamic Saint-Venant equations. For a river network modeled with several Strahler orders of tributaries, comprehensive and consistent synoptic data are typically lacking and synthetic starting conditions are needed. Because of underlying nonlinearity, poorly defined or inconsistent initial conditions can lead to convergence problems and long spin-up times in an unsteady solver. Two new approaches are defined and demonstrated herein for computing flows and cross-sectional areas (or depths). These methods can produce an initial condition data set that is consistent with modeled landscape runoff and river geometry boundary conditions at the initial time. These new methods are (1) the pseudo time-marching method (PTM) that iterates toward a steady-state initial condition using an unsteady Saint-Venant solver and (2) the steady-solution method (SSM) that makes use of graph theory for initial flow rates and solution of a steady-state 1-D momentum equation for the channel cross-sectional areas. The PTM is shown to be adequate for short river reaches but is significantly slower and has occasional non-convergent behavior for large river networks. The SSM approach is shown to provide a rapid solution of consistent initial conditions for both small and large networks, albeit with the requirement that additional code must be written rather than applying an existing unsteady Saint-Venant solver.

Mapping and predictive variations of soil bacterial richness across France

PubMed Central

Dequietd, Samuel; Saby, Nicolas P. A.; Lelièvre, Mélanie; Nowak, Virginie; Tripied, Julie; Régnier, Tiffanie; Jolivet, Claudy; Arrouays, Dominique; Wincker, Patrick; Cruaud, Corinne; Karimi, Battle; Bispo, Antonio; Maron, Pierre Alain; Chemidlin Prévost-Bouré, Nicolas; Ranjard, Lionel

2017-01-01

Although numerous studies have demonstrated the key role of bacterial diversity in soil functions and ecosystem services, little is known about the variations and determinants of such diversity on a nationwide scale. The overall objectives of this study were i) to describe the bacterial taxonomic richness variations across France, ii) to identify the ecological processes (i.e. selection by the environment and dispersal limitation) influencing this distribution, and iii) to develop a statistical predictive model of soil bacterial richness. We used the French Soil Quality Monitoring Network (RMQS), which covers all of France with 2,173 sites. The soil bacterial richness (i.e. OTU number) was determined by pyrosequencing 16S rRNA genes and related to the soil characteristics, climatic conditions, geomorphology, land use and space. Mapping of bacterial richness revealed a heterogeneous spatial distribution, structured into patches of about 111km, where the main drivers were the soil physico-chemical properties (18% of explained variance), the spatial descriptors (5.25%, 1.89% and 1.02% for the fine, medium and coarse scales, respectively), and the land use (1.4%). Based on these drivers, a predictive model was developed, which allows a good prediction of the bacterial richness (R2adj of 0.56) and provides a reference value for a given pedoclimatic condition. PMID:29059218

Case Study of a College that Closed: Saint Mary's College

ERIC Educational Resources Information Center

Brown, Alice W.

2011-01-01

Few colleges choose to close. One that did was Saint Mary's College in Raleigh, North Carolina. Although trustees resisted for a decade, they ultimately made the decision before an anticipated denial of accreditation, allowing the college to control its final days in ways not possible for those who wait until an outside agency forces closure. This…

Potential impact of a nonavalent HPV vaccine on the occurrence of HPV-related diseases in France.

PubMed

Riethmuller, Didier; Jacquard, Anne-Carole; Lacau St Guily, Jean; Aubin, François; Carcopino, Xavier; Pradat, Pierre; Dahlab, André; Prétet, Jean-Luc

2015-05-02

Human Papillomavirus (HPV) infection is known to be associated with a number of conditions including cervical, vaginal, vulvar, penile, anal neoplasias and cancers, oropharynx cancers and genitals warts (GW). Two prophylactic vaccines are currently available: a bivalent vaccine designed to prevent HPV type 16 and 18 infection and a quadrivalent vaccine targeting HPV 6, 11, 16, and 18. In France, HPV vaccination is recommended in 11-14 year-old girls with a catch-up for girls aged 15-19. The objective of this study was to assess the potential impact of an HPV 6/11/16/18/31/33/45/52/58 nonavalent vaccine on anogenital and oropharyngeal HPV-related diseases in France. HPV genotype distributions from 6 multicentric retrospective studies (EDiTH I to VI) were analyzed including 516 cases of invasive cervical cancers (ICC), 493 high-grade cervical neoplasias (CIN2/3), 397 low-grade squamous intraepithelial lesions (LSIL), 423 GW, 366 anal cancer and 314 oropharyngeal carcinomas. Low and high estimates of HPV vaccine impact were calculated as follows: low estimate: prevalence of HPV 6/11/16/18/31/33/45/52/58 genotypes alone or in association but excluding presence of another HPV type; high estimate: prevalence of HPV 6/11/16/18/31/33/45/52/58 genotypes alone or in association, possibly in presence of another HPV type. Estimates of potential impact varied from 85% (low estimate) to 92% (high estimate) for ICC, 77% to 90% for CIN2/3, 26% to 56% for LSIL, 69% to 90% for GW, 81% to 93% for anal cancer, and 41% to 44% for oropharyngeal carcinomas. Compared to the quadrivalent vaccine, the proportion of additional cases potentially prevented by the nonavalent vaccine was 9.9%-15.3% for ICC, 24.7%-33.3% for CIN2/3, 12.3%-22.7% for LSIL, 2.1%-5.4% for GW, 8.5%-10.4% for anal cancer, and 0.0%-1.6% for oropharyngeal carcinoma. The nonavalent HPV vaccine showed significant increased potential impact compared to the HPV 6/11/16/18 quadrivalent vaccine for ICC, CIN2/3 and LSIL

Populations at Risk for Alveolar Echinococcosis, France

PubMed Central

Piarroux, Martine; Piarroux, Renaud; Knapp, Jenny; Bardonnet, Karine; Dumortier, Jérôme; Watelet, Jérôme; Gerard, Alain; Beytout, Jean; Abergel, Armand; Bresson-Hadni, Solange

2013-01-01

During 1982–2007, alveolar echinococcosis (AE) was diagnosed in 407 patients in France, a country previously known to register half of all European patients. To better define high-risk groups in France, we conducted a national registry-based study to identify areas where persons were at risk and spatial clusters of cases. We interviewed 180 AE patients about their way of life and compared responses to those of 517 controls. We found that almost all AE patients lived in 22 départements in eastern and central France (relative risk 78.63, 95% CI 52.84–117.02). Classification and regression tree analysis showed that the main risk factor was living in AE-endemic areas. There, most at-risk populations lived in rural settings (odds ratio [OR] 66.67, 95% CI 6.21–464.51 for farmers and OR 6.98, 95% CI 2.88–18.25 for other persons) or gardened in nonrural settings (OR 4.30, 95% CI 1.82–10.91). These findings can help sensitization campaigns focus on specific groups. PMID:23647623

Comparison of rehospitalization rates in France and the United States.

PubMed

Gusmano, Michael; Rodwin, Victor; Weisz, Daniel; Cottenet, Jonathan; Quantin, Catherine

2015-01-01

To compare rates of 30-day all-cause rehospitalization in France and the US among patients aged 65 years and older and explain any difference between the countries. To calculate rehospitalization rates in France, we use an individual identifying variable in the national hospital administrative dataset to track unique individuals aged 65 years or more hospitalized in France in 2010. To calculate the proportion of rehospitalized patients (65+) who received outpatient visits between the time of initial discharge and rehospitalization, we linked the hospital database with a database that includes all medical and surgical admissions. We used step by step regression models to predict rehospitalization. Rates of rehospitalization in France (14.7%) are lower than among Medicare beneficiaries in the US (20%). We find that age, sex, patient morbidity and the ownership status of the hospital are all correlated with rehospitalization in France. Lower rates of rehospitalization in France appear to be due to a combination of better access to primary care, better health among the older French population, longer lengths of stay in French hospitals and the fact that French nursing homes do not face the same financial incentive to rehospitalize residents. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

[Saints and illnesses in faith and paleopathological evidences].

PubMed

Fulcheri, Ezio

2006-01-01

The exhumation of the natural mummies of Beata Margherita di Savoia (1390-1464) and of St. Caterina Fieschi Adorno (1447-1510) has not been followed by autopsy or histological exams. The aim has been to preserve the integrity of the saints' corpses. We have thus proceeded to a confrontation between data gathered from chronicles and hagiographies and radiological exams and macroscopic observations. The article aims at establishing a model for a multidisciplinar approach to paleopathological research, integrating historical research and medical knowledge.

Performance-based organizations : issues for the Saint Lawrence Seaway Development Corporation proposal

DOT National Transportation Integrated Search

1997-05-01

Report to Congressional Committees. This report (1) compares the characteristics of the Next Steps program and the PBO concept and (2) describes the changes and effects the PBO concept potentially could have on the Saint Lawrence Seaway Development C...

French Army - Family Psychological and Social Support

DTIC Science & Technology

2006-04-01

Major de l’armée de Terre, Bureau condition du personnel 14 rue Saint-Dominique 00453 Armées FRANCE The French Army is permanently engaged on...ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) French Army...RTO-MP-HFM-134 21E - 1 French Army – Family Psychological and Social Support LCL G. BOUILLAUD French Army Staff, Quality Of Life Etat

33 CFR 165.T09-0290 - Safety Zones; Blasting Operations and Movement of Explosives, St. Marys River, Sault Sainte Marie...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety Zones; Blasting Operations and Movement of Explosives, St. Marys River, Sault Sainte Marie, MI. 165.T09-0290 Section 165.T09-0290... Movement of Explosives, St. Marys River, Sault Sainte Marie, MI. (a) Location. The following areas are...

[On the medical and publishing activities of the community of Saint Eugene].

PubMed

2012-01-01

The article deals with the role the physicians played in organization and functioning of the Community of Saint Eugene in St. Petersburg in 1882-1918. The typography production of the Community being of interest for history of medicine is examined.

Paracelsus confronts the saints: miracles, healing and the secularization of magic.

PubMed

Webster, C

1995-12-01

The sixteenth and seventeenth centuries witnessed an erosion of the role played by the church in healing. Magical practices mediated by the church were replaced by the resources of medicine. This represented an important cultural development and it is often regarded as a manifestation of increasing secularization, the decline of magic and rise of science. This paper examines this issue with special reference to miraculous healing associated with saints, which constituted one of the most important facets of magic controlled by the church. It will be suggested that Paracelsus (Theophrast von Hohenheim, 1493-1541) played an important part in the argument concerning the miraculous powers of saints. Many works by Paracelsus produced at various points in his career were relevant to this issue, but De causis morborum invisibilium, the sequel to his important Opus Paraminum (1531), was especially significant. The question of miraculous healing was therefore important in the first, full presentation of the new system of medicine developed by Paracelsus. Modern commentators have understandably found De causis morborum invisibilium less intelligible and congenial than the more accessible Opus Paramirum. But the former was important to Paracelsus, and it addressed problems that were fundamental to his audience. This case-study shows how conclusions reached by Paracelsus about medical questions were integrally tied up with his theological standpoint and with his wider reaction to the acute crisis of confidence which affected the church and the established social order at the beginning of the sixteenth century. By eliminating the miraculous intervention of saints and promoting the secularization of magic, Paracelsus was contributing to one of the important cultural changes associated with the Reformation.

Erratum: Erratum to: The Quadrennial Ozone Symposium 2016

NASA Astrophysics Data System (ADS)

Godin-Beekmann, Sophie; Petropavlovskikh, Irina; Reis, Stefan; Newman, Paul; Steinbrecht, Wolfgang; Rex, Markus; Santee, Michelle L.; Eckman, Richard S.; Zheng, Xiangdong; Tully, Matthew B.; Stevenson, David S.; Young, Paul; Pyle, John; Weber, Mark; Tamminen, Johanna; Mills, Gina; Bais, Alkiviadis F.; Heaviside, Clare; Zerefos, Christos

2018-03-01

The Quadrennial Ozone Symposium 2016 Sophie GODIN-BEEKMANN*1, Irina PETROPAVLOVSKIKH2, Stefan REIS3,20, Paul NEWMAN4, Wolfgang STEINBRECHT5, Markus REX6, Michelle L. SANTEE7, Richard S. ECKMAN8, Xiangdong ZHENG9, Matthew B. TULLY10, David S. STEVENSON11, Paul YOUNG12, John PYLE13, Mark WEBER14, Johanna TAMMINEN15, Gina MILLS16, Alkiviadis F. BAIS17, Clare HEAVISIDE18, and Christos ZEREFOS19 1 Observatoire de Versailles Saint-Quentin en Yvelines, Université de Versailles Saint-Quentin-en-Yvelines, CNRS, 78280 Guyancourt, France 2 CIRES, University of Colorado, Boulder, CO 80309, USA 3 NERC Centre for Ecology & Hydrology, Edinburgh EH26 0QB, UK 4 Goddard Space Flight Center, NASA, Greenbelt, MD 20771, USA 5 Hohenpeissenberg Meteorological Observatory, Deutscher Wetterdienst, 82383 Hohenpeissenberg, Germany 6 Alfred Wegener Institute, 14401 Potsdam, Germany 7 Jet Propulsion Laboratory, California Institute of Technology, CA 91109, USA 8 NASA Headquarters, Earth Science Division, Washington, DC, USA 9 Chinese Academy of Meteorological Sciences, Beijing, 100081, China 10 Bureau of Meteorology, Melbourne, Victoria 3001, Australia 11 University of Edinburgh, School of GeoSciences, Edinburgh EH9 3FE, UK 12 Lancaster Environment Centre, Lancaster University, Lancaster LA1 4YQ, UK 13 University of Cambridge, Department of Chemistry, Cambridge CB2 1EW, UK 14 University of Bremen, Institute of Environmental Physics, 28359 Bremen, Germany 15 Finnish Meteorological Institute, Earth Observation, FI-00101 Helsinki, Finland 16 NERC Centre for Ecology and Hydrology, Bangor, Gwynedd LL57 2UW, Wales, UK 17 Aristotle University of Thessaloniki, Thessaloniki, Greece 18 Public Health England, Centre for Radiation, Chemical and Environmental Hazards, London, UK 19 Research Center for Atmospheric Physics & Climatology, Academy of Athens, Athens 10680, Greece 20 University of Exeter Medical School, Truro TR1 3HD, UK

France Without NATO

DTIC Science & Technology

1966-04-08

and unstable France . Two decades of European peace and prosperity are causing the French to reevaluate the threat from the East and to question the...continued need for alliances in which France is not the dominate power. The French attacks on the North Atlantic Treaty Organization and the...distracted or compromised in his belief of French greatness, stands the "man who is France ," President Charles de Gaulle. France has gained strength

Metal contamination of sediments and soils of Bayou Saint John: a potential health impact to local fishermen?

PubMed

Welt, Marc; Mielke, Howard W; Gonzales, Chris; Cooper, Kora M; Batiste, Corey G; Cresswell, Lawrence H; Mielke, Paul W

2003-12-01

This research examines the pattern of sediment contamination of an urban bayou of New Orleans (formerly a natural waterway) and the potential for human exposure from consumption of fish caught in the bayou. Sediments and soils of Bayou Saint John were evaluated for lead (Pb), zinc (Zn), and cadmium (Cd). Sediment cores were collected at bridges (n = 130) and sites between the bridges (n = 303) of the bayou. In addition, soil samples (n = 66) were collected along the banks of the bayou. Sediments below the bridges contain significantly more (p-value approximately 10(-7)) Pb and Zn (medians of 241 and 230 mg kg(-1), respectively) than bayou sediments located between bridges (medians of 64 and 77 mg kg(-1), respectively). Sediments below bridges of the upper reaches of the bayou contain significantly larger amounts of metals (p < 10(-14) for Pb and Zn and p approximately 10(-8) for Cd) (medians of 329, 383 and 1.5, respectively) than sediments below bridges in the lower reaches of the bayou (medians of 43, 31 and 0.5 for Pb, Zn and Cd, respectively). Likewise, medians for sediments located between bridges contain significantly (p < 10(-14)) higher quantities of Pb, Zn and Cd (170, 203 and 1.8 mg kg(-1), respectively) in the upper bayou than Pb, Zn, and Cd (48, 32, and 0.8 mg kg(-1), respectively) in the lower reaches of the bayou. The potential risk for human exposure may be magnified by the fact that fishing generally occurs from the numerous bridges that cross the bayou. Poor and minority people do most of the fishing. Most people (87%) indicated they ate fish they caught from the Bayou.

Homelessness and Work Experience: Two Years in Saint Paul. Final Report.

ERIC Educational Resources Information Center

Davis, Dennis R.

A study explored the role of work experience in addressing problems of homeless people in Saint Paul (Minnesota) during the 1989-91 grant cycles of the McKinney Job Training for the Homeless Demonstration Program. The program included a number of elements: outreach, intake, assessment and enrollment, orientation, work experience, basic…

Concordia U. Saint Paul Will Slash Tuition by One-Third

ERIC Educational Resources Information Center

Supiano, Beckie

2012-01-01

Concordia University Saint Paul will reduce the sticker price of its tuition and fees by $10,000, or about 33 percent, for the 2013-2014 academic year. Tuition and fees for all new and returning students in the traditional undergraduate program will drop to $19,700 next year from $29,700 this year, while the price of room and board will not…

Development of flood-inundation maps for the Mississippi River in Saint Paul, Minnesota

USGS Publications Warehouse

Czuba, Christiana R.; Fallon, James D.; Lewis, Corby R.; Cooper, Diane F.

2014-01-01

Digital flood-inundation maps for a 6.3-mile reach of the Mississippi River in Saint Paul, Minnesota, were developed through a multi-agency effort by the U.S. Geological Survey in cooperation with the U.S. Army Corps of Engineers and in collaboration with the National Weather Service. The inundation maps, which can be accessed through the U.S. Geological Survey Flood Inundation Mapping Science Web site at http://water.usgs.gov/osw/flood_inundation/ and the National Weather Service Advanced Hydrologic Prediction Service site at http://water.weather.gov/ahps/inundation.php, depict estimates of the areal extent and depth of flooding corresponding to selected water levels (stages) at the U.S. Geological Survey streamgage at the Mississippi River at Saint Paul (05331000). The National Weather Service forecasted peak-stage information at the streamgage may be used in conjunction with the maps developed in this study to show predicted areas of flood inundation. In this study, flood profiles were computed for the Mississippi River by means of a one-dimensional step-backwater model. The hydraulic model was calibrated using the most recent stage-discharge relation at the Robert Street location (rating curve number 38.0) of the Mississippi River at Saint Paul (streamgage 05331000), as well as an approximate water-surface elevation-discharge relation at the Mississippi River at South Saint Paul (U.S. Army Corps of Engineers streamgage SSPM5). The model also was verified against observed high-water marks from the recent 2011 flood event and the water-surface profile from existing flood insurance studies. The hydraulic model was then used to determine 25 water-surface profiles for flood stages at 1-foot intervals ranging from approximately bankfull stage to greater than the highest recorded stage at streamgage 05331000. The simulated water-surface profiles were then combined with a geographic information system digital elevation model, derived from high-resolution topography

A comparative analysis of the epidemiological impact and disease cost-savings of HPV vaccines in France.

PubMed

Bresse, Xavier; Adam, Marjorie; Largeron, Nathalie; Roze, Stephane; Marty, Rémi

2013-04-01

The aim was to compare the epidemiological and economic impact of 16/18 bivalent and 6/11/16/18 quadrivalent HPV vaccination in France, considering differences in licensed outcomes, protection against non-vaccine HPV types and prevention of HPV-6/11-related diseases. The differential impact of the two vaccines was evaluated using a published model adapted to the French setting. The target population was females aged 14-23 y and the time horizon was 100 y. A total of eight different scenarios compared vaccination impact in terms of reduction in HPV-16/18-associated carcinomas (cervical, vulvar, vaginal, anal, penile and head and neck), HPV-6/11-related genital warts and recurrent respiratory papillomatosis, and incremental reduction in cervical cancer due to potential cross-protection. Quadrivalent vaccine was associated with total discounted cost savings ranging from EUR 544-1,020 million vs. EUR 177-538 million with the bivalent vaccination (100-y time horizon). Genital wart prevention thanks to quadrivalent HPV vaccination accounted for EUR 306-380 million savings (37-56% of costs saved). In contrast, the maximal assumed cross-protection against cervical cancer resulted in EUR 13-33 million savings (4%). Prevention of vulvar, vaginal and anal cancers accounted for additional EUR 71-89 million savings (13%). In France, the quadrivalent HPV vaccination would result in significant incremental epidemiological and economic benefits vs. the bivalent vaccination, driven primarily by prevention of genital. The present analysis is the first in the French setting to consider the impact of HPV vaccination on all HPV diseases and non-vaccine types.

Assessing various approaches for flash flood forecasting in the Yzeron periurban catchment (150 km2) south-east Lyon, France

NASA Astrophysics Data System (ADS)

Braud, Isabelle; Breil, Pascal; Javelle, Pierre; Pejakovic, Nikola; Guérin, Stéphane

2017-04-01

The Yzeron periurban catchment (150 km2) is prone to flash floods leading to overflow in the downstream part of the catchment. A prevention and management plan has been approved and the set-up of a flood forecasting system is planned. The present study presents a comparison of several solutions for flood forecasting in the catchment. It is based on an extensive data collection (rain gauges, radar/rain gauge reanalyses, discharge and water level data) from this experimental catchment. A set of rainfall-runoff events leading to floods (problematic and non-problematic floods) was extracted and formed the basis for the definition of a first forecasting method. It is based on data analysis and the identification of explaining factors amongst the following: rainfall amount, intensity, antecedent rainfall, initial discharge. Several statistical methods including Factorial Analysis of Mixed Data and Classification and Regression Tree were used for this purpose. They showed that several classes of problematic floods can be identified. The first one is related to wet conditions characterized with high initial discharge and antecedent rainfall. The second class is driven by rainfall amount, initial discharge and rainfall intensity. Thresholds of these variables can be identified to provide a first warning. The second forecasting method assessed in the study is the system that will be operational in France in 2017, based on the AIGA method (Javelle et al., 2016). For this purpose, 18-year discharge simulation using the hydrological model of the AIGA method, forced using radar/rain gauges reanalysis were available at 44 locations within the catchment. The dates for which quantiles of a given return period were overtopped were identified and compared with the list of problematic events. The AIGA method was found relevant in identifying the most problematic events, but the lead time needs further investigation in order to assess the usefulness for population warning. References

SRTM Anaglyph with Landsat Overlay: Miquelon and Saint Pierre Islands

NASA Technical Reports Server (NTRS)

2000-01-01

This anaglyph satellite image shows Miquelon and Saint Pierre Islands, located south of Newfoundland, Canada. These islands are a self-governing territory of France. A 'tombolo' (sand bar) unites Grande Miquelon to the north and Petite Miquelon to the south. Saint Pierre Island, located to the lower right, includes a harbor, an airport, and a small town. Glaciers once covered these islands and the direction of glacial flow is evident in the topography as striations and shoreline trends running from the upper right to the lower left. The darkest image features are freshwater lakes that fill glacially carved depressions and saltwater lagoons that are bordered by barrier beaches. The lakes and the lagoons are fairly calm waters and reflect less sunlight than do the wave covered and sediment laden nearshore ocean currents.

The stereoscopic effect was created by first draping a Landsat satellite image over preliminary digital elevation data from the Shuttle Radar Topography Mission (SRTM), and then generating two differing perspectives, one for each eye. When viewed through special glasses, the result is a vertically exaggerated view of the Earth's surface in its full three dimensions. Anaglyph glasses cover the left eye with a red filter and cover the right eye with a blue filter.

Landsat has been providing visible and infrared views of the Earth since 1972. SRTM elevation data matches the 30-meter resolution of most Landsat images and will substantially help in analyses of the large and growing Landsat image archive. The Landsat 7 Thematic Mapper image used here was provided to the SRTM project by the United States Geological Survey, Earth Resources Observation Systems (EROS) DataCenter, Sioux Falls, South Dakota.

The elevation data used in this image was acquired by SRTM aboard the Space Shuttle Endeavour, launched on February 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR

[Courses in microsurgical techniques in France and abroad].

PubMed

Alzakri, A; Al-Rajeh, M; Liverneaux, P A; Facca, S

2014-06-01

The objective of this work was to determine the state of current training programs for microsurgery in France and abroad. Our survey of microsurgery training programs determined the registration volume, program contents, and number of students in France, and looked at registration volume and teaching time for programs abroad. Data were obtained from the Internet, university administration, those responsible for university diploma programs, and students. There were 18 university diploma programs in microsurgery in France. The average list price was €1,129 for an average of 19 hours of theoretical training and 100 hours of practice. Evaluation methods varied, but all required at least vascular anastomosis in rats. In 2011-2012, 148 students were enrolled and 126 graduated (85% passing rate). Abroad, 16 basic courses were listed in the USA, Europe and Asia. Nine advanced courses were offered. The average price was $1,346 for 36 hours of practice in the basic courses and $1,955 for over 50 hours of training in advanced courses. None of these courses gave out a diploma. Our results show that in France, university diploma programs in microsurgery are heterogeneous and the French College should consider updating them. Globally, a study is underway by the International Microsurgical Simulation Society. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Three saints with deformed extremities in an Italian Renaissance altarpiece.

PubMed

Albury, W R; Weisz, G M

2017-03-01

A fifteenth-century Florentine altarpiece painted by the Pollaiuolo brothers, Antonio (1433-1498) and Piero (1443-1496), shows three saints with evident deformities of the hands and feet. The pathologies concerned are tentatively identified, and various rationales for their presence in the painting are discussed. Of particular importance is the location of the altarpiece in a chapel which houses the tomb of the Cardinal of Portugal, Prince James of Lusitania (1433-1459). It is argued that both the artistic style of the day and the religious symbolism of the Cardinal's funeral chapel contributed to the artists' decision to portray the saints with deformities. An unnatural curvature of the fifth finger was apparently considered elegant in fifteenth-century paintings, and the depiction of bare feet with hallux valgus gave them a shape which approximated and could have been caused by fashionable pointed shoes. But in addition, deformities in religious art could be symbolic of suffering and martyrdom, a theme which the Cardinal's chapel emphasised in a number of ways. It is suggested therefore that the Pollaiuolo altarpiece reconciles these two disparate factors, portraying genuine deformities in a way that was artistically stylish and symbolically meaningful.

Dental caries, tooth wear and diet in an adult medieval (12th-14th century) population from mediterranean France.

PubMed

Esclassan, R; Grimoud, A M; Ruas, M P; Donat, R; Sevin, A; Astie, F; Lucas, S; Crubezy, E

2009-03-01

The aims of the present work were to determine the frequency and distribution of caries and tooth wear on paired maxillae of a mediaeval sample from southwest France in which the sex of the remains had been established, and to make a relation with the diet of this population. The sample analysed consisted of the dental remains of 58 adult individuals (29 men and 29 women) excavated from the mediaeval cemetery of the archaeological site of Vilarnau d'Amont (southwest France). A total of 1395 teeth were examined. The frequency of ante-mortem tooth loss for the sample was 8.7% and the frequency of caries was 17.5%. The frequencies of carious lesions in adult men and women's dentition were 21.9% and 14.0%. The most frequent were occlusal (49.7% and 34.3%) and approximal caries (26.5% and 37.4%). Concerning tooth wear, all 58 individuals were affected by attrition (100%) and more than 90% of the teeth were concerned. Most of them showed the presence of dentin clusters. There was no significant difference between men and women for caries and tooth wear. These findings are similar to those of other studies on European populations of the same socio-economic status and confirm the predominance of tooth wear over carious lesions during this period. Both caries and tooth wear may be related to the regional diet of this rural population.

Feedback on floods in Var, south of France, 15th June 2010 : different societal impacts and responses linked to levels of prevention, organization and information

NASA Astrophysics Data System (ADS)

Moreau, K.; Roumagnac, A.

2010-09-01

Observing the last dramatical floods in Var in south of France on 15th June 2010, very differents responses and impacts can be identified. 23 death, people missing, more than 50 communities impacted, 700 Millions Euros of damages were to declare after the event. Most of human loss, 12 people, were to deplore in Draguignan in Var were 270 mm of rainfall were registered in the city center. This tragedy reminds all the necessity of prevention, organization and communication. In term of flood disaster, the fact is that physical protection is necessary but inevitably limited. To manage these kinds of crisis, local authorities need to be able to base their policy against flood on prevention, warnings, post-crisis analysis and feedback from former experience. While many damages were observed in Draguignan, the event was different in Hyères, Sainte-Maxime, Cogolin, Grimaud or Toulon who behaved to face it by minimizing the effects, and economic impacts of the flood. The fact is that they had prepared their organization to face flood crisis, they had informed the population of what had to be done, they had given security advices, they had reacted from the vigilance information and kept on being informed during the event to adapt their plans and actions: opening security centers, closing roads before they get flooded, evacuating when necessary. The most relevant example is in Sainte-Maxime where 260 mm of rainfall were registered in the city center, a volume close to the 270 mm registered in Draguignan during the same event. In Sainte-Maxime, no human loss was to deplore, the community was informed, had the information of rainfall intensity and rainfall effects in anticipation and could inform the citizen with the help of the police circulating and communicating in the streets. Getting informed the citizen could elevate and protect their property, evacuate their cars on the hights of the community, and secure themselves and family. Comparing this event with what happened in

Latter-Day Saint Women and Leadership: The Influence of Their Religious Worldview

ERIC Educational Resources Information Center

Madsen, Susan R.

2016-01-01

The article examines theories, assumptions, concepts, experiences, and practices from the Latter-day Saints' (LDS, or the Mormons) religious worldview to expand existing theoretical constructs and implications of leadership development and education for women. The article elucidates LDS doctrine and culture regarding women and provides specific…

[Images of nursing mothers in France, 18th and 19th centuries].

PubMed

Morel, Marie-France

2010-01-01

As they became more widely adopted in eighteenth- and nineteenth-century France, wet-nursing and wet-nurses appeared prominently in the iconography of the time. Such images turned negative as criticism against “mercenary breast-feeding” mounted. Over the nineteenth century in particular, wet-nurses were heavily featured in press caricatures: they were being mocked while described as simple-minded, dumb, greedy creatures, with proclivities ranging from a taste for garish attire, to sexual appetites fuelling trysts in public gardens with soldiers on leave. A representative sample of such images will be selected to highlight the codes and values underpinning this mockery.

18 CFR 1312.14 - Determination of archaeological or commercial value and cost of restoration and repair.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Determination of archaeological or commercial value and cost of restoration and repair. 1312.14 Section 1312.14 Conservation of... part shall be its fair market value. Where the violation has resulted in damage to the archaeological...

THEORIES AND PRACTICES IN THE EDUCATION OF WOMEN DURING THE AGE OF ENLIGHTMENT IN FRANCE.

ERIC Educational Resources Information Center

FRIEDMAN, LEONARD M.

A REPORT WAS GIVEN ON A SEARCH OF THE LITERATURE ON THE EDUCATION OF WOMEN IN FRANCE DURING THE PERIOD FROM THE FOUNDING OF ST. CYR (1686) THROUGH THE REVOLUTION. THE AUTHOR SUMMARIZES (1) THE EDUCATIONAL PRACTICES USED AND (2) THE EDUCATIONAL THEORIES PROPOSED AT THAT TIME. WHILE THE EDUCATION OF WOMEN IN 18TH-CENTURY FRANCE LEFT MUCH TO BE…

Saint John's wort, an herbal inducer of the cytochrome P4503A4 isoform, may alleviate symptoms of Willis-Ekbom's disease

PubMed Central

Pereira, José Carlos; Pradella-Hallinan, Márcia; Alves, Rosana Cardoso

2013-01-01

OBJECTIVE: Certain drug classes alleviate the symptoms of Willis-Ekbom's disease, whereas others aggravate them. The pharmacological profiles of these drugs suggest that drugs that alleviate Willis-Ekbom's disease inhibit thyroid hormone activity, whereas drugs that aggravate Willis-Ekbom's disease increase thyroid hormone activity. These different effects may be secondary to the opposing actions that drugs have on the CYP4503A4 enzyme isoform. Drugs that worsen the symptoms of the Willis-Ekbom's disease inhibit the CYP4503A4 isoform, and drugs that ameliorate the symptoms induce CYP4503A4. The aim of this study is to determine whether Saint John's wort, as an inducer of the CYP4503A4 isoform, diminishes the severity of Willis-Ekbom's disease symptoms by increasing the metabolism of thyroid hormone in treated patients. METHODS: In an open-label pilot trial, we treated 21 Willis-Ekbom's disease patients with a concentrated extract of Saint John's wort at a daily dose of 300 mg over the course of three months. RESULTS: Saint John's wort reduced the severity of Willis-Ekbom's disease symptoms in 17 of the 21 patients. CONCLUSION: Results of this trial suggest that Saint John's wort may benefit some Willis-Ekbom's disease patients. However, as this trial was not placebo-controlled, the extent to which Saint John's wort is effective as a Willis-Ekbom's disease treatment will depend on future, blinded placebo-controlled studies. PMID:23778343

Prevalence of pain medication prescriptions in France, Germany, and the UK - a cross-sectional study including 4,270,142 patients.

PubMed

Jacob, Louis; Kostev, Karel

2018-01-01

The goal of the present study was to analyze the prevalence of pain medication prescriptions in general practices in France, Germany, and the UK. This study included all patients aged ≥18 years followed in 2016 in general practitioner practices in France, Germany and the UK. The primary outcome was the prevalence of patients receiving prescriptions for pain medications in France, Germany, and the UK in 2016. The following drugs were included in the analysis: anti-inflammatory and antirheumatic products, non-steroids and analgesics including opioids, antimigraine preparations, and other analgesics and antipyretics. Demographic variables included age and gender. This study included 4,270,142 patients. The prevalences of pain medication prescriptions were 57.3% in France, 29.6% in Germany, and 21.7% in the UK. Although this prevalence generally remained consistent between age groups in France (54.3%-60.3%), it increased with age in Germany (18-30 years: 23.8%; >70 years: 35.8%) and in the UK (18-30 years: 9.3%; >70 years: 43.8%). Finally, the prevalence of pain medication prescriptions was higher in women than in men in all three countries. Paracetamol was prescribed to 82.3% and 60.1% of patients receiving pain medication in France and the UK, respectively, whereas ibuprofen was prescribed to 46.5% of individuals in Germany. The prevalence of pain medication prescriptions was higher in France than in Germany and the UK. Further research is needed to gain a better understanding of the differences in the prescription patterns between these three European countries.

A Comparison of Secondary Chemistry Courses and Chemistry Teacher Preparation Programs in Iowa and Saint Petersburg, Russia

NASA Astrophysics Data System (ADS)

Sanger, Michael J.; Brincks, Erik L.; Phelps, Amy J.; Pak, Maria S.; Lyovkin, Antony N.

2001-09-01

This paper, which is a result of the collaboration between the University of Northern Iowa (UNI) in Cedar Falls, Iowa, and Herzen State Pedagogical University of Russia in Saint Petersburg, compares the 7-12 chemistry courses in Iowa and Saint Petersburg and the chemistry teacher preparation programs at UNI and Herzen. Differences in the 7-12 chemistry courses include curriculum design (spiral versus layer cake), students' extracurricular activities, and access to technology in the classroom. Differences in the chemistry teacher preparation programs include the number of methods and chemistry content courses required, the number of chemistry teaching majors, the proportion of teaching majors enrolled in the different natural science programs, and the typical minors and endorsements received by these majors. Although we noted many differences in chemistry instruction between Iowa and Saint Petersburg, the secondary and college instructors still face many similar issues, which include overcoming student chemophobia, improving students' algorithmic and problem-solving skills, improving students' conceptual understanding at the particulate level, and dealing with shortages in qualified secondary science teachers.

14 CFR 1207.102 - Waiver of prohibition in 18 U.S.C. 208.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Waiver of prohibition in 18 U.S.C. 208. 1207.102 Section 1207.102 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION STANDARDS OF... in an official capacity in any particular matter in which, to their knowledge, they, or any person...

Pollen-based biomes for Beringia 18,000, 6000 and 0 14C yr BP

USGS Publications Warehouse

Edwards, M.E.; Anderson, P.M.; Brubaker, L.B.; Ager, T.A.; Andreev, A.A.; Bigelow, N.H.; Cwynar, L.C.; Eisner, Wendy R.; Harrison, S.P.; Hu, F.-S.; Jolly, D.; Lozhkin, A.V.; MacDonald, G.M.; Mock, Cary J.; Ritchie, J.C.; Sher, A.V.; Spear, R.W.; Williams, J.W.; Yu, G.

2000-01-01

The objective biomization method developed by Prentice et al. (1996) for Europe was extended using modern pollen samples from Beringia and then applied to fossil pollen data to reconstruct palaeovegetation patterns at 6000 and 18,000 14C yr BP. The predicted modern distribution of tundra, taiga and cool conifer forests in Alaska and north-western Canada generally corresponds well to actual vegetation patterns, although sites in regions characterized today by a mosaic of forest and tundra vegetation tend to be preferentially assigned to tundra. Siberian larch forests are delimited less well, probably due to the extreme under-representation of Larix in pollen spectra. The biome distribution across Beringia at 6000 14C yr BP was broadly similar to today, with little change in the northern forest limit, except for a possible northward-advance in the Mackenzie delta region. The western forest limit in Alaska was probably east of its modern position. At 18,000 14C yr BP the whole of Beringia was covered by tundra. However, the importance of the various plant functional types varied from site to site, supporting the idea that the vegetation cover was a mosaic of different tundra types.

64Cu-p-NH2-Bn-DOTA-hu14.18K322A, a PET radiotracer targeting neuroblastoma and melanoma.

PubMed

Vavere, Amy L; Butch, Elizabeth R; Dearling, Jason L J; Packard, Alan B; Navid, Fariba; Shulkin, Barry L; Barfield, Raymond C; Snyder, Scott E

2012-11-01

The hu14.18K322A variant of the GD2-targeting antibody hu14.18 has been shown to elicit a level of antibody-dependent cell-mediated cytotoxicity toward human neuroblastoma cells similar to that of the parent antibody. However, hu14.18K322A exhibited a decreased complement activation and associated pain, the dose-limiting toxicity in neuroblastoma immunotherapy. PET with a radiolabeled analog of the same antibody used in treatment will provide insight into the ability of hu14.18K322A to reach its target, as well as nontarget uptake that may cause side effects. Such antibody radiotracers might also provide a method for measuring GD2 expression in tumors, thus enabling the prediction of response to anti-GD2 therapy for individual patients. The conjugation of hu14.18K322A with p-NH(2)-Bn-DOTA was accomplished using N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide with subsequent (64)Cu radiolabeling at 37°C for 30 min. Immunoreactivity of the conjugate was assessed by a dose-escalation blocking experiment measuring binding to purified GD2 versus GD1b as a negative control. Cell uptake and biodistribution studies in M21 (GD2-positive) and PC-3 (GD2-negative) tumor models were performed, as was small-animal PET/CT of M21 and PC-3 tumor-bearing mice. The labeling of (64)Cu-p-NH(2)-Bn-DOTA-hu14.18K322A was achieved at more than 95% radiochemical purity and a specific activity of 127-370 MBq/mg (3.4-10 mCi/mg) after chromatographic purification. Preliminary in vitro data demonstrated a greater than 6-fold selectivity of binding to GD2 versus GD1b and dose-dependent inhibition of binding by unmodified hu14.8K322A. In vivo data, including small-animal PET/CT, showed significant GD2-positive tumor-targeting ability, with a persistent 2-fold-higher uptake of radiotracer than in GD2-negative tumors. (64)Cu-p-NH(2)-Bn-DOTA-hu14.18K322A represents a novel PET radiotracer to facilitate clinical investigations of anti-GD2 immunotherapies and to complement other imaging modalities in

Predictive Factors of Cytomegalovirus Seropositivity among Pregnant Women in Paris, France

PubMed Central

N’Diaye, Dieynaba S.; Yazdanpanah, Yazdan; Krivine, Anne; Andrieu, Thibaut; Rozenberg, Flore; Picone, Olivier; Tsatsaris, Vassilis; Goffinet, François; Launay, Odile

2014-01-01

Background Cytomegalovirus (CMV) is the most frequent cause of congenital infection. The objective of this study was to evaluate predictive factors for CMV seronegativity in a cohort of pregnant women in Paris, France. Methods Pregnant women enrolled in a prospective cohort during the 2009 A/H1N1 pandemic were tested for CMV IgG antibodies. Variables collected were age, geographic origin, lifestyle, work characteristics, socioeconomic status, gravidity, parity and number of children at home. A multivariate logistic regression model was used to identify independent predictive factors for CMV seropositivity. Results Among the 826 women enrolled, 389 (47.1%) were primiparous, and 552 (67.1%) had Metropolitan France as a geographic origin. Out of these, 355 (i.e. 57.0%, 95% confidence interval (CI): [53.6%–60.4%]) were CMV seropositive: 43.7% (95% CI:[39.5%–47.9%]) in those whose geographic origin was Metropolitan France and 84.1% in those with other origins (95% CI:[79.2%–88.3%]). Determinants associated with CMV seropositivity in a multivariate logistic regression model were: (i) geographic origin (p<0.001(compared with Metropolitan France, geographic origins of Africa adjusted odds ratio (aOR) 21.2, 95% CI:[9.7–46.5], French overseas departments and territories and other origin, aOR 7.5, 95% CI:[3.9–14.6], and Europe or Asia, aOR 2.2, 95% CI: [1.3–3.7]); and (ii) gravidity (p = 0.019), (compared with gravidity = 1, if gravidity≥3, aOR = 1.5, 95% CI: [1.1–2.2]; if gravidity = 2, aOR = 1.0, 95% CI: [0.7–1.4]). Work characteristics and socioeconomic status were not independently associated with CMV seropositivity. Conclusions In this cohort of pregnant women, a geographic origin of Metropolitan France and a low gravidity were predictive factors for CMV low seropositivity. Such women are therefore the likely target population for prevention of CMV infection during pregnancy in France. PMID:24587077

High-Precision Half-Life Measurements for the Superallowed Fermi β+ Emitters 14O and 18Ne

NASA Astrophysics Data System (ADS)

Laffoley, A. T.; Andreoiu, C.; Austin, R. A. E.; Ball, G. C.; Bender, P. C.; Bidaman, H.; Bildstein, V.; Blank, B.; Bouzomita, H.; Cross, D. S.; Deng, G.; Diaz Varela, A.; Dunlop, M. R.; Dunlop, R.; Finlay, P.; Garnsworthy, A. B.; Garrett, P.; Giovinazzo, J.; Grinyer, G. F.; Grinyer, J.; Hadinia, B.; Jamieson, D. S.; Jigmeddorj, B.; Ketelhut, S.; Kisliuk, D.; Leach, K. G.; Leslie, J. R.; MacLean, A.; Miller, D.; Mills, B.; Moukaddam, M.; Radich, A. J.; Rajabali, M. M.; Rand, E. T.; Svensson, C. E.; Tardiff, E.; Thomas, J. C.; Turko, J.; Voss, P.; Unsworth, C.

High-precision half-life measurements, at the level of ±0.04%, for the superallowed Fermi emitters 14O and 18Ne have been performed at TRIUMF's Isotope Separator and Accelerator facility. Using 3 independent detector systems, a gas-proportional counter, a fast plastic scintillator, and a high-purity germanium array, a series of direct β and γ counting measurements were performed for each of the isotopes. In the case of 14O, these measurements were made to help resolve an existing discrepancy between detection methods, whereas for 18Ne the half-life precision has been improved in anticipation of forthcoming high-precision branching ratio measurements.

A comparative analysis of the epidemiological impact and disease cost-savings of HPV vaccines in France

PubMed Central

Bresse, Xavier; Adam, Marjorie; Largeron, Nathalie; Roze, Stephane; Marty, Remi

2013-01-01

The aim was to compare the epidemiological and economic impact of 16/18 bivalent and 6/11/16/18 quadrivalent HPV vaccination in France, considering differences in licensed outcomes, protection against non-vaccine HPV types and prevention of HPV-6/11-related diseases. The differential impact of the two vaccines was evaluated using a published model adapted to the French setting. The target population was females aged 14–23 y and the time horizon was 100 y. A total of eight different scenarios compared vaccination impact in terms of reduction in HPV-16/18-associated carcinomas (cervical, vulvar, vaginal, anal, penile and head and neck), HPV-6/11-related genital warts and recurrent respiratory papillomatosis, and incremental reduction in cervical cancer due to potential cross-protection. Quadrivalent vaccine was associated with total discounted cost savings ranging from EUR 544–1,020 million vs. EUR 177–538 million with the bivalent vaccination (100-y time horizon). Genital wart prevention thanks to quadrivalent HPV vaccination accounted for EUR 306–380 million savings (37–56% of costs saved). In contrast, the maximal assumed cross-protection against cervical cancer resulted in EUR 13–33 million savings (4%). Prevention of vulvar, vaginal and anal cancers accounted for additional EUR 71–89 million savings (13%). In France, the quadrivalent HPV vaccination would result in significant incremental epidemiological and economic benefits vs. the bivalent vaccination, driven primarily by prevention of genital. The present analysis is the first in the French setting to consider the impact of HPV vaccination on all HPV diseases and non-vaccine types. PMID:23563511

France: Factors Shaping Foreign Policy, and Issues in U.S.-French Relations

DTIC Science & Technology

2005-01-10

Policy, and Issues in U.S.- French Relations 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK...298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 France : Factors Shaping Foreign Policy, and Issues in U.S.- French Relations Summary The factors that...shape French foreign policy have changed since the end of the Cold War. The perspectives of France and the United States have diverged in some cases

France: Factors Shaping Foreign Policy, and Issues in U.S.-French Relations

DTIC Science & Technology

2006-05-19

Policy, and Issues in U.S.- French Relations 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK...298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 France : Factors Shaping Foreign Policy, and Issues in U.S.- French Relations Summary The factors that...shape French foreign policy have changed since the end of the Cold War. The perspectives of France and the United States have diverged in some cases

Mount Saint Helens, Washington, USA, SRTM Perspective: Shaded Relief and Colored Height

NASA Technical Reports Server (NTRS)

2004-01-01

Mount Saint Helens is a prime example of how Earth's topographic form can greatly change even within our lifetimes. The mountain is one of several prominent volcanoes of the Cascade Range that stretches from British Columbia, Canada, southward through Washington, Oregon, and into northern California. Mount Adams (left background) and Mount Hood (right background) are also seen in this view, which was created entirely from elevation data produced by the Shuttle Radar Topography Mission.

Prior to 1980, Mount Saint Helens had a shape roughly similar to other Cascade peaks, a tall, bold, irregular conic form that rose to 2950 meters (9677 feet). However, the explosive eruption of May 18, 1980, caused the upper 400 meters (1300 feet) of the mountain to collapse, slide, and spread northward, covering much of the adjacent terrain (lower left), leaving a crater atop the greatly shortened mountain. Subsequent eruptions built a volcanic dome within the crater, and the high rainfall of this area lead to substantial erosion of the poorly consolidated landslide material.

Eruptions at Mount Saint Helens subsided in 1986, but renewed volcanic activity here and at other Cascade volcanoes is inevitable. Predicting such eruptions still presents challenges, but migration of magma within these volcanoes often produces distinctive seismic activity and minor but measurable topographic changes that can give warning of a potential eruption.

Three visualization methods were combined to produce this image: shading of topographic slopes, color coding of topographic height, and then projection into a perspective view. The shade image was derived by computing topographic slope in the northeast-southwest (left to right) direction, so that northeast slopes appear bright and southwest slopes appear dark. Color coding is directly related to topographic height, with green at the lower elevations, rising through yellow and tan, to white at the highest elevations. The perspective

Myeloid Antigen-positive T Cell Acute Lymphocytic Leukemia with t(14;18) and Trisomy 10: Report of a Case and Literature Review.

PubMed

Lin, Guoqiang; Liu, Limin; Zhao, Guangsheng; Si, Yejun; Zhang, Xingxia; Sun, Yumei; Lu, Shuhua; Zhang, Yanming

2015-08-01

The chromosomal translocation t(14;18)(q32;q21) is commonly associated with neoplasms of follicular center cell origin and has also been reported in cases of chronic lymphocytic leukemia. However, T cell acute lymphoblastic (or lymphocytic) leukemia (T-ALL) with t(14;18)(q32;q21) has been rarely reported. Here, we report a case of myeloid antigen-positive T-ALL (My+T-ALL) with t(14;18)(q32;q21) and trisomy 10. This is the first reported case of My+T-ALL (L2) with such chromosomal abnormalities. Other published de novo ALL cases, with t(14;18)(q32;q21) and without a documented history of lymphoma, are summarized and reviewed in this report. The patient in this study was treated with remission induction therapy and intensive chemotherapy, followed by maintenance therapy. As of this writing, he has remained in remission for more than 3 years and has presented a better clinical outcome compared with other reported adult ALL patients with t(14;18)(q32;q21).

SRTM Stereo Pair with Landsat Overlay: Miquelon and Saint Pierre Islands

NASA Technical Reports Server (NTRS)

2000-01-01

This stereoscopic satellite image shows Miquelon and Saint Pierre Islands, located south of Newfoundland, Canada. These islands are a self-governing territory of France. A 'tombolo' (sand bar) unites Grande Miquelon to the north and Petite Miquelon to the south. Saint Pierre Island, located to the lower right, includes a harbor, an airport, and a small town. Glaciers once covered these islands and the direction of glacial flow is evident in the topography as striations and shoreline trends running from the upper right to the lower left. The darkest image features are freshwater lakes that fill glacially carved depressions and saltwater lagoons that are bordered by barrier beaches. The lakes and the lagoons are fairly calm waters and reflect less sunlight than do the wave covered and sediment laden nearshore ocean currents.

This stereoscopic image was generated by draping a Landsat satellite image over a preliminary Shuttle Radar Topography Mission (SRTM)elevation model. Two differing perspectives were then calculated, one for each eye. They can be seen in 3-D by viewing the left image with the right eye and the right image with the left eye (cross-eyed viewing), or by downloading and printing the image pair and viewing them with a stereoscope. When stereoscopically merged, the result is a vertically exaggerated view of the Earth's surface in its full three dimensions.

Landsat has been providing visible and infrared views of the Earth since 1972. SRTM elevation data matches the 30-meter resolution of most Landsat images and will substantially help in analyses of the large and growing Landsat image archive. The Landsat 7 Thematic Mapper image used here was provided to the SRTM project by the United States Geological Survey, Earth Resources Observation Systems (EROS) DataCenter, Sioux Falls, South Dakota.

The elevation data used in this image was acquired by SRTM aboard the Space Shuttle Endeavour, launched on February 11, 2000. SRTM used the same radar

Enhancing the IT Infrastructure at Saint Philip's Hospital: Point-of-Care Solutions

ERIC Educational Resources Information Center

Naydenova, Iva; White, Bruce

2013-01-01

Healthcare has become a rapidly changing field. With the introduction of value-based purchasing to determine reimbursement of Medicare providers based on the quality of care in addition to outcomes in treatment, the environment is becoming ever more competitive. Saint Philip's Hospital is among the largest non-profit hospitals in the nation…

Lightcurve and Rotation Period Determination for 2578 Saint- Exupery, 4297 Eichhorn, 10132 Lummelunda and (21766) 1999 RW208.

NASA Astrophysics Data System (ADS)

Salvaggio, Fabio; Banfi, Massimo; Marchini, Alessandro; Papini, Riccardo

2018-04-01

Photometric observations of the main-belt asteroids 2578 Saint-Exupery, 4297 Eichhorn, 10132 Lummelunda and (21766) 1999 RW208 performed by the authors from June to December 2017, revealed the bimodal light curves phased to 8.146 ± 0.001 h for 2578 Saint-Exupery, 4.105 ± 0.003 h for 4297 Eichhorn, 2.51 ± 0.03 h for 10132 Lummellunda and 5.841 ± 0.001 h for (21766) 1999 RW208 as the most likely solutions representing the synodic rotation periods for these asteroids.

Chemical and isotopic characteristics of geothermal fluids from Sulphur Springs, Saint Lucia

NASA Astrophysics Data System (ADS)

Joseph, Erouscilla P.; Fournier, Nicolas; Lindsay, Jan M.; Robertson, Richard; Beckles, Denise M.

2013-03-01

Sulphur Springs is a vigorous, geothermal field associated with the active Soufrière Volcanic Centre in southern Saint Lucia, Lesser Antilles island arc. The 'Sulphur Springs Park' is an important tourist attraction (touted as the 'world's only drive-through volcano') with some of the hot pools being developed into recreational pools. Some 200,000 people visit the park each year. Since 2001, the hydrothermal fluids of Sulphur Springs have been sampled as part of an integrated volcanic monitoring programme for the island. Gas and water samples were analysed to characterise the geochemistry of the hydrothermal system, and to assess the equilibrium state and subsurface temperatures of the reservoir. This has also enabled us, for the first time, to establish baseline data for future geochemical monitoring. The gases are of typical arc-type composition, with N2 excess and low He and Ar content. The dry gas composition is dominated by CO2 (ranging from 601-993 mmol/mol), with deeper magmatic sourced H2S-rich vapour undergoing boiling and redox changes in the geothermal reservoir to emerge with a hydrothermal signature in the fumarolic gases. Fluid contributions from magmatic degassing are also evident, mainly from the moderate to high contents of HCl and deeply-sourced H2S gas, respectively. Sulphur Springs hydrothermal waters have acid-sulphate type compositions (SO4 = 78-4008 mg/L; pH = 3-7), and are of primarily meteoric origin which have been affected by evaporation processes based on the enrichment in both δ18O and δD (δ18O = - 1 to 15‰ and δD = - 9 to 14‰ respectively) in relation to the global meteoric water line (GMWL). These waters are steam-heated water typically formed by absorption of H2S-rich gases in the near surface oxygenated groundwaters. Reservoir temperatures calculated from the evaluation of gas equilibria in the CO2-CH4-H2 system reveal higher temperatures (190 to 300 °C) than those derived from quartz geothermometry (95 to 169 °C), which

The Spirit of France

DTIC Science & Technology

1994-01-01

seemed to boost self esteem amongst the French , giving France a greater sense of dignity. Charles de Gaulle sought grandeur to unite France and give...overshadowed by the US, UK and Russia. The war had left France with little influence in Europe and had psychologically and morally weakened the French ... France as a way to increase the influence base of the French state. Influence, either perceived or real, meant power. Power represented independence

Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography.

PubMed

Toyama, Hiroshi; Ichise, Masanori; Liow, Jeih-San; Modell, Kendra J; Vines, Douglass C; Esaki, Takanori; Cook, Michelle; Seidel, Jurgen; Sokoloff, Louis; Green, Michael V; Innis, Robert B

2004-08-01

The purpose of this study was to evaluate the feasibility of absolute quantification of regional cerebral glucose utilization (rCMR(glc)) in mice by use of (18)F-FDG and a small animal PET scanner. rCMR(glc) determined with (18)F-FDG PET was compared with values determined simultaneously by the autoradiographic 2-(14)C-DG method. In addition, we compared the rCMR(glc) values under isoflurane, ketamine and xylazine anesthesia, and awake states. Immediately after injection of (18)F-FDG and 2-(14)C-DG into mice, timed arterial samples were drawn over 45 min to determine the time courses of (18)F-FDG and 2-(14)C-DG. Animals were euthanized at 45 min and their brain was imaged with the PET scanner. The brains were then processed for 2-(14)C-DG autoradiography. Regions of interest were manually placed over cortical regions on corresponding coronal (18)F-FDG PET and 2-(14)C-DG autoradiographic images. rCMR(glc) values were calculated for both tracers by the autoradiographic 2-(14)C-DG method with modifications for the different rate and lumped constants for the 2 tracers. Average rCMR(glc) values in cerebral cortex with (18)F-FDG PET under normoglycemic conditions (isoflurane and awake) were generally lower (by 8.3%) but strongly correlated with those of 2-(14)C-DG (r(2) = 0.95). On the other hand, under hyperglycemic conditions (ketamine/xylazine) average cortical rCMR(glc) values with (18)F-FDG PET were higher (by 17.3%) than those with 2-(14)C-DG. Values for rCMR(glc) and uptake (percentage injected dose per gram [%ID/g]) with (18)F-FDG PET were significantly lower under both isoflurane and ketamine/xylazine anesthesia than in the awake mice. However, the reductions of rCMR(glc) were markedly greater under isoflurane (by 57%) than under ketamine and xylazine (by 19%), whereas more marked reductions of %ID/g were observed with ketamine/xylazine (by 54%) than with isoflurane (by 37%). These reverse differences between isoflurane and ketamine/xylazine may be due to

18 CFR 1301.14 - Times, places, and requirements for identification of individuals making requests.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Times, places, and... and Water Resources TENNESSEE VALLEY AUTHORITY PROCEDURES Privacy Act § 1301.14 Times, places, and requirements for identification of individuals making requests. (a) TVA will require proof of identity, in...

[The embroidery work of the lady at Saint-Anne Hospital].

PubMed

Thillaud, Pierre L; Postel, Jacques

2014-01-01

In July 1974, a 72 old woman had been a patient for forty years in Sainte-Anne Hospital, Ward C. As she had again a violent brawl with her neighbour patient, she revealed being a tremendous artist. She had been confined on account of dementia paralytica in the Mecca of malariotherapy, and passionately devoted herself to embroidery. Her fancy work was rather a matter for Jean Dubuffet's art through its perfect expression and deserved being known.

[School bathrooms: children's perceptions and prevalence of gastrointestinal and urinary disorders, a survey in 3 secondary schools near Saint-Etienne].

PubMed

Hoarau, Bénédicte; Vercherin, Paul; Bois, Christophe

2014-01-01

Irregular use of toilets can contribute to urinary and gastrointestinal disorders. The aim of this study was to assess the prevalence of gastrointestinal and urinary symptoms among a secondary school teenage population and to evaluate their perception and use of school toilets. 791 adolescents aged 12 to 16 filled in an anonymous questionnaire, which was administered in three secondary schools near Saint-Etienne, France. 22% reported abdominal pain at least once a week during the past two months and 26% experienced abdominal pain about once every month. 9% of schoolchildren suffered from urinary incontinence at least once during the two months before the study: 4% of boys and 13% of girls. Children had a negative perception of school toilets: 62% didn't feel safe and 54% of boys reported a lack of privacy. 34% of students avoided school toilets: 21% never used them to urinate and 85% never used them to defecate. 28% of children acknowledged they had experienced abdominal pain because they couldn't use school toilets and 29% said that they had experienced poor concentration as a result of their pain. Abdominal pain and urinary disorders are common among secondary schoolchildren. Stool and urine withholding behaviours are be widespread and affect students' concentration while at school.

ORIGINS AND GENETIC DIVERSITY OF INTRODUCED POPULATIONS OF THE PUERTO RICAN RED-EYED COQUÍ, ELEUTHERODACTYLUS ANTILLENSIS, IN SAINT CROIX (U.S. VIRGIN ISLANDS) AND PANAMÁ

PubMed Central

Barker, Brittany S.; Rodríguez-Robles, Javier A.

2017-01-01

The Red-eyed Coquí, Eleutherodactylus antillensis, is a terrestrial frog endemic to the Puerto Rican Bank (Puerto Rico and numerous islands and cays off its eastern coast), in the eastern Caribbean Sea. The species was likely introduced in Saint Croix, an island c. 100 km southeast of Puerto Rico, in the late 1930s, and in Panamá City, Panamá, in the late 1950s or early 1960s, but the source(s) of these introductions are unknown. We analyzed sequence data from one mtDNA locus and four nuDNA introns to infer the origin(s) of the Saint Croix and Panamá City populations and quantify their genetic diversity. Saint Croix and Panamanian populations do not share any haplotypes, and they cluster with different native populations, suggesting that they are derived from separate sources in the Puerto Rican Bank. Patterns of population structure trace the probable sources of E. antillensis in Saint Croix to islands off Puerto Rico’s eastern coast, which include Vieques, Culebra, Saint Thomas, Saint John, Tortola, and Virgin Gorda, and possibly to eastern Puerto Rico as well. In contrast, Panamá City E. antillensis probably originated from either western or eastern Puerto Rico. Genetic diversity in the introduced populations is similar to or lower than in populations in the species’ native range, indicating that genetic diversity has not increased in the alien frogs. Our findings may facilitate the development of preventive measures to minimize introductions of non-native amphibians in the Caribbean and Central America. PMID:28649148

Saint Anthony Hospital: Infusing Developmental and Family Support Services in Community-Based Medical Practice

ERIC Educational Resources Information Center

Casas, Paula; Isarowong, Nucha

2015-01-01

Physicians affiliated with small community hospitals face numerous barriers to using developmentally oriented best practices in primary care with young children. Saint Anthony Hospital's Developmental Support Project model promotes improved developmental outcomes for children through two complementary strands of services: (a) training and…

Recent Evolution of the Mont Saint-Michel Bay as seen by ALOS AVNIR-2 Data (ADEN AO 3643)

NASA Astrophysics Data System (ADS)

Deroin, Jean-Paul; Bilaudeau, Clelia; Deffontaines, Benoit

2008-11-01

The ALOS AVNIR-2 scene acquired on October 24, 2007 has been used for drawing a new map of the Mont Saint-Michel Bay. This area is characterised by a large dry-fallen tidal flat, one of the largest in the world. The tidal records indicate that the ALOS datatake was acquired in favorable conditions, the elevation of the sea at 2.56 m being very close to the theoretical minimum value (about 2.30 m). In these conditions, the largest tidal flat observed by a sun-synchronous satellite on the Mont Saint-Michel Bay is exposed.

Family structure and childhood anthropometry in Saint Paul, Minnesota in 1918

PubMed Central

Warren, John Robert

2017-01-01

Concern with childhood nutrition prompted numerous surveys of children’s growth in the United States after 1870. The Children’s Bureau’s 1918 “Weighing and Measuring Test” measured two million children to produce the first official American growth norms. Individual data for 14,000 children survives from the Saint Paul, Minnesota survey whose stature closely approximated national norms. As well as anthropometry the survey recorded exact ages, street address and full name. These variables allow linkage to the 1920 census to obtain demographic and socioeconomic information. We matched 72% of children to census families creating a sample of nearly 10,000 children. Children in the entire survey (linked set) averaged 0.74 (0.72) standard deviations below modern WHO height-for-age standards, and 0.48 (0.46) standard deviations below modern weight-for-age norms. Sibship size strongly influenced height-for-age, and had weaker influence on weight-for-age. Each additional child six or underreduced height-for-age scores by 0.07 standard deviations (95% CI: −0.03, 0.11). Teenage siblings had little effect on height-forage. Social class effects were substantial. Children of laborers averaged half a standard deviation shorter than children of professionals. Family structure and socio-economic status had compounding impacts on children’s stature. PMID:28943749

18. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. (4"X5" image enlarged from 2 1/4" negative) Sam Fowler, Photographer, February 1998 VIEW OF GEORGIA DOT BRIDGE NO. 051-00025D-01986N (JAMES P. HOULIHAN BRIDGE) APPROACH SPAN FENDER. DOLPHIN LOCATED AT RIGHT. NAVIGATIONAL LIGHT LOCATED ON TOP OF FENDER - Georgia DOT Bridge No. 051-00025D-01986N, US 17 & State Route 25 Spanning Savannah River, Port Wentworth, Chatham County, GA

Legislative Review. A Look at Higher Education in Week 6: February 14-18, 2011

ERIC Educational Resources Information Center

North Dakota University System, 2011

2011-01-01

This issue of "Legislative Review" takes a look at the news in higher education from February 14 to 18, 2011. This Legislative Review reports that: (1) HB 1003, the University System budget bill, was amended by House Appropriations, Education and Environment Division, February 17 and approved as amended by the full House Appropriations…

International Workshop on Beam Injection Assessment of Defects in Semiconductors Held in Meudon-Bellevue (France) on 18-20 July 1988

DTIC Science & Technology

1989-07-20

Krause , Phys. Stat. Sol. (a) 102, 443 (1987) 2) \\1. Tajima, in "Defects and Properties of Semiconductors: Defect Engineering", edited by J. Chikawa (Tokyo...illustrate that the newly developed electron optical column satisfies all the requirements for internal measurements on VLSI circuits. (1] E. Wolfgang ...JEME29, rue Jeanne Marvig 13397 MARSEILLE CEDE-X 13 31400 TOULOUSE FRANCE FRANCE PICQUERA-S Javier- SCHROTER Wolfgang Dpto de Fisica de Materiales IV

Saint Lawrence Seaway Navigation-Aid System Study : Volume I - Text and Appendixes A and D

DOT National Transportation Integrated Search

1978-09-01

The requirements for a navigation guidance system which will effect an increase in the ship processing capacity of the Saint Lawrence Seaway (Lake Ontario to Montreal, Quebec) are developed. The requirements include a specification of system position...

Regional Development and Vocational Training. The Problems of Evaluation. Colloquium (Limoges, France, June 18-19, 1990).

ERIC Educational Resources Information Center

Pierret, M.

1990-01-01

This paper summarizes the proceedings of a conference held to discuss evaluation in vocational education. The agenda included welcome speeches and the introductory address by Robert Savy, President of the Regional Council of Limousin (France); an opening session with statements from representatives of the Commission of the European Communities…

Long-Term Care Financing: Lessons From France

PubMed Central

Doty, Pamela; Nadash, Pamela; Racco, Nathalie

2015-01-01

Context An aging population leads to a growing demand for long-term services and supports (LTSS). In 2002, France introduced universal, income-adjusted, public long-term care coverage for adults 60 and older, whereas the United States funds means-tested benefits only. Both countries have private long-term care insurance (LTCI) markets: American policies create alternatives to out-of-pocket spending and protect purchasers from relying on Medicaid. Sales, however, have stagnated, and the market's viability is uncertain. In France, private LTCI supplements public coverage, and sales are growing, although its potential to alleviate the long-term care financing problem is unclear. We explore whether France's very different approach to structuring public and private financing for long-term care could inform the United States’ long-term care financing reform efforts. Methods We consulted insurance experts and conducted a detailed review of public reports, academic studies, and other documents to understand the public and private LTCI systems in France, their advantages and disadvantages, and the factors affecting their development. Findings France provides universal public coverage for paid assistance with functional dependency for people 60 and older. Benefits are steeply income adjusted and amounts are low. Nevertheless, expenditures have exceeded projections, burdening local governments. Private supplemental insurance covers 11% of French, mostly middle-income adults (versus 3% of Americans 18 and older). Whether policyholders will maintain employer-sponsored coverage after retirement is not known. The government's interest in pursuing an explicit public/private partnership has waned under President François Hollande, a centrist socialist, in contrast to the previous center-right leader, President Nicolas Sarkozy, thereby reducing the prospects of a coordinated public/private strategy. Conclusions American private insurers are showing increasing interest in long

College of Saint Teresa: Design for Choicemakers. An Operations Manual for Faculty and Staff.

ERIC Educational Resources Information Center

Batell, Susan; And Others

The College of Saint Teresa's value-based educational program, known as "Design for Choicemakers," is described. The program is designed to foster students' holistic learning and personal development, based on cooperation among the academic affairs, student affairs, and pastoral affairs offices. The links between the curriculum and…

The crystal structure of tetranatrolite from Mont Saint-Hilaire, Quebec, and its chemical and structural relationship to paranatrolite and gonnardite

USGS Publications Warehouse

Evans, H.T.; Konnert, J.A.; Ross, M.

2000-01-01

The structure of tetranatrolite from Mont Saint-Hilaire, Quebec (U.S. National Museum sample R1830) with a = 13.197(7) A, c = 6.630(9) A, and space group I42d, was refined using single-crystal X-ray data. A representative formula of tetranatrolite determined from electron microprobe analysis is Na12.50K0.01Ca2.93Sr0.11Al19.09 Si20.91O79.74??nH2O. The structure has the basic natrolite Si-Al-O framework configuration with Na, Ca, Sr, and K residing within inter-framework cages. Aluminum is disordered over the T1 and T2 tetrahedral sites, with T2 > T1. Water molecules O4 and O5 coordinate the intercage atoms and have high displacement parameters, indicating disorder within the cages. The Mont Saint-Hilaire tetranatrolite structure is compared to four previously determined structures, two tetranatrolite samples from Khibiny and Lovozero, Russia and two "gonnardite" samples from Tvedalen, Norway and Gignat, France. Observations are given to indicate that the Norwegian sample deduced to be tetranatrolite rather than gonnardite. Although the crystal structures of tetranatrolite and gonnardite are very similar, it is shown that the tetranatrolite compositions differ significantly from those of gonnardite. The tetranatrolite composition series varies along the join Na16Al16Si24O80-Na12 Ca4Al20Si20O80, and is represented by the formula Na16-xCaxAl16+xSi24-x O80??nH2O, where x extends from approximately 2.4 to 3.9. In contrast, gonnardites from Arkansas and Austria have compositions that vary along the join Na16Al16Si24O80-Na4 Ca8Al20Si20O80, which are represented by the formula ???xNa16-3xCa2xAl16+x Si24-xO80??nH2O and where ??? indicates vacant intercage cation sites and x varies from approximately 0.3 to 3.2. Tetranatrolite is a dehydration product of paranatrolite and probably does not have a true stability field.

The t(14;18) translocation is absent from endothelial and follicular dendritic cells of follicular lymphoma (FL) and shows heterogeneous presence in preserved FL mantle zones.

PubMed

Kosmidis, Perikles; Mankel, Barbara; Fend, Falko; Adam, Patrick

2018-05-02

The translocation t(14;18)(q32;q21) is the genetic hallmark of follicular lymphoma (FL) and can be observed in 85-90% of cases. Whether the translocation is restricted to cells with germinal center B-cell phenotype or can be observed in other cell types of the microenvironment remains debated. Of interest, cases of associated histiocytic and dendritic cell sarcomas arising in the background of FL have been shown to be clonally related and carry the t(14;18), suggesting a "transdifferentiation" of the malignant FL clone into a neoplasm of a different hematopoietic lineage. We analyzed the presence of the t(14;18)(q32;q21) as a surrogate marker of the malignant clone in cells of the FL microenvironment using combined fluorescence immunophenotyping and interphase cytogenetics targeting the BCL2 gene locus. In addition to non-lymphoid cells in FL, we analysed FL with preserved IgD+ mantle zones and cases of in situ follicular neoplasia (ISFN) to investigate whether cells of non-germinal center B-cell phenotype are part of the malignant clone. Six (40%) of 15 manifest FL cases with preserved IgD+ mantle zones did not harbour the t(14;18)(q32;q21) translocation. In all t(14;18) + FL cases, follicular dendritic cells and endothelial cells lacked the t(14;18) translocation. 2/9 FL revealed t(14;18)- IgD+ mantle zone B-cells. In the seven ISFN cases, the t(14;18) translocation was strictly confined to germinal center cells. The t(14;18) translocation in follicular lymphoma is limited to B-cells. The origin of IgD+ mantle cells is heterogeneous, in the majority of cases belonging to the neoplastic clone, whereas a minority of cases of manifest FL show nonneoplastic mantle zones, similar to ISFN.

Baldrige Award cites two hospitals. Baptist, Saint Luke's hospitals honored for quality, performance.

PubMed

Rees, Tom

2004-01-01

Baptist Hospital Inc., Pensacola, Fla.; and Saint Luke's Hospital, Kansas City, Mo., have received the prestigious Malcolm Baldrige National Quality Award in the category of healthcare. Named for a former secretary of commerce, the award recognizes efficiency, effectiveness and excellence. The two hospitals are among only seven companies in the U.S. to be so recognized this year.

Correlates of Lifetime History of Purchasing Sex Services by Men in Saint Petersburg and Leningrad Oblast, Russia.

PubMed

Girchenko, P; Ompad, D C; Kulchynska, R; Bikmukhametov, D; Dugin, S; Gensburg, L

2015-12-01

Commercial sex workers (CSWs) in the Russian Federation are at high risk of HIV infection and transmission as a result of unsafe sexual and injecting behaviors. Their clients might be at increased risk of acquiring HIV; however, little is known about the population of men purchasing sex services. This study aims to investigate factors associated with a history of purchasing sex services by men in Saint Petersburg and Leningrad Oblast, Russian Federation. Data were collected as part of a cross-sectional study offering free anonymous rapid HIV testing in Saint Petersburg and Leningrad Oblast in 2014; in total, 3565 men aged 18 years and older provided information about their behaviors associated with risk of acquiring HIV during face-to-face interviews. Prevalence of CSW use in our study was 23.9%. Multivariable analyses using log-binomial regression were stratified by self-reported HIV testing during the 12 months preceding the study interview. In both strata, older age, multiple sex partners, and a history of sex with an injection drug user (IDU) were associated with an elevated prevalence ratio (PR) for history of purchasing sex services, although the strength of the association differed by strata. Among men who reported recent HIV testing, condom use (PR = 1.22, 90% confidence interval (CI) 1.0, 1.48) was associated with a history of purchasing sex services, and among men who did not report recent HIV testing, having a consistent sex partner was associated with purchasing sex services (PR = 1.23, 90% CI 1.1, 1.37). The high prevalence of CSW service use and associations found in this study raise serious concerns about potential for sexual HIV transmission and should be investigated more closely.

New optical museum at Saint-Petersburg for education and training

NASA Astrophysics Data System (ADS)

Vasil'ev, V. N.; Stafeef, S. K.; Tomilin, M. G.

2009-06-01

Nowadays the educational problem of teaching optics and photonics is to attract the young generation to the wonderful and magic world of light, optical science, technology and systems. The main issue is to explain that in the course of last several hundred years optics has been representing the most clear world view for humanity. In fact, the optics itself is a multidisciplinary complex of independent scientific directions, and, moreover, it has always been a generator of new fields of knowledge. Besides, optics and photonics are the fields within which the most fundamental problems of today's reality are to be resolved. It is absolutely necessary to encourage our scholars in getting optics and photonics education as an alternative physical basis to gaining solely computer knowledge. The main obstacle is the poor connection between program of optical education and the real optical researches, disintegration of different branches of the optical science, the demographic situation, some problems with teaching mathematics and physics at schools, and the collision between traditional educational methods and the mentality of the new generation. In Russia the Saint-Petersburg State University of Information Technologies, Mechanics and Optics offers partial solution to these problems: the organization of a real place for interactive optical science in a form of a new museum of optics, intended for education and training, seems to be the most effective way. This was the main reason for establishing such a museum in Saint-Petersburg at the end of 2008.

Romanticism or Reality? An Exploration of Frances Mary Hendry's "Chandra."

ERIC Educational Resources Information Center

Johnson, Jilaine

This paper singles out a novel written for children about India, "Chandra" (1995) by Frances Mary Hendry, as a powerful and useful novel to present to today's 11 to 14 year old students. The paper contends that the novel allows students to explore and consider different value systems, challenges them to become aware of prejudice and the…

France and European Security

DTIC Science & Technology

1986-04-01

block number) In the 1960s, French defense policy emphasized the protection of French territory rather than the collective security of France and her... France and her European allies. This began to change in the late 1970s. The French contribution to European security is now a matter of considerable...independence. He interpreted independence in a specific manner. Although France would maintain ties and commitments to its allies, the French government

Characterization of the large fire regime in SE France

Treesearch

Anne Ganteaume; Marielle Jappiot

2015-01-01

Southeastern France is the most wildfire prone region of the country, covering 14.7 percent of its land area-entire country, is the region most affected by wildfires, with 55 percent of the total number of fires recorded in the whole country from 2006 to 2008. It is a typical Mediterranean climate with hot and dry summers, often with strong NW wind, and includes plant...

The Evolution of Minehunting in France (L’Evolution de la Chasse aux Mines en France),

DTIC Science & Technology

1983-07-13

The Necessity of Minehunting in France And why are the French , Ohl such a small number of experts, interested in minehunting? The coasts of France are...AD-A132 532 THE EVOLUTION OF MINEHUNTING IN FRANCE IL’EVOLUTION DE I/1 LA CHASSE AUX MINES EN FRANCE )(U) NAVAL INTELLIGENCE SUPPORT CENTER WASHINGTON...MINEHUNTING IN FRANCE AUTHOR: DE DREZIGUE TRANSLATEO gY: LCDR ROBERT AUGELLI, USNR-R NISC TRANSLATION UNIT 0166 eei o DTIC MI’S OR&I DfIC T ELECTE Ja~tinoati

Facts and fiction: the death of Saint Ignatius of Loyola.

PubMed

Rosenman, L D

1996-01-01

The biography of Ignatius of Loyola, the sainted founder of the Society of Jesus (the Jesuits), ends with his death in curious circumstances. A careful search of the available sources written from the time of his death in 1556 to the present has reviewed the evidence. The evidence does not support the claims for a diagnosis that has been used for four centuries. So-called historical "facts" simply are the opinions of historians. Ignatius may have suffered from hyperparathyroidism that led to his death rather than from a cholangioportal venous fistula.

Strategic proposal for a national trauma system in France.

PubMed

Gauss, Tobias; Balandraud, Paul; Frandon, Julien; Abba, Julio; Ageron, Francois Xavier; Albaladejo, Pierre; Arvieux, Catherine; Barbois, Sandrine; Bijok, Benjamin; Bobbia, Xavier; Charbit, Jonathan; Cook, Fabrice; David, Jean-Stephane; Maurice, Guillaume De Saint; Duranteau, Jacques; Garrigue, Delphine; Gay, Emmanuel; Geeraerts, Thomas; Ghelfi, Julien; Hamada, Sophie; Harrois, Anatole; Kobeiter, Hicham; Leone, Marc; Levrat, Albrice; Mirek, Sebastien; Nadji, Abdel; Paugam-Burtz, Catherine; Payen, Jean Francois; Perbet, Sebastien; Pirracchio, Romain; Plenier, Isabelle; Pottecher, Julien; Rigal, Sylvain; Riou, Bruno; Savary, Dominique; Secheresse, Thierry; Tazarourte, Karim; Thony, Frederic; Tonetti, Jerome; Tresallet, Christophe; Wey, Pierre-Francois; Picard, Julien; Bouzat, Pierre

2018-05-29

In this road map for trauma in France, we focus on the main challenges for system implementation, surgical and radiology training, and upon innovative training techniques. Regarding system organisation: procedures for triage, designation and certification of trauma centres are mandatory to implement trauma networks on a national scale. Data collection with registries must be created, with a core dataset defined and applied through all registries. Regarding surgical and radiology training, diagnostic-imaging processes should be standardised and the role of the interventional radiologist within the trauma team and the trauma network should be clearly defined. Education in surgery for trauma is crucial and recent changes in medical training in France will promote trauma surgery as a specific sub-specialty. Innovative training techniques should be implemented and be based on common objectives, scenarios and evaluation, so as to improve individual and team performances. The group formulated 14 proposals that should help to structure and improve major trauma management in France over the next 10 years. Copyright © 2018 Société française d'anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved.

Germany, France and NATO

DTIC Science & Technology

1994-10-17

the Alliance. Ii. France and NATO. " The French position on NAI 0 has evolved since 1990. Rance has moved toward closer military cooperation with...NATO as demonstrated, for example, by the subcrdination c! French troops in the EUROCORPS io SACFUR when a crisis demands it, " Yet France has also...future. Greater cooperation may develop between France and the United Kingdom, particularly in nuclear matters, as indicated in the French White

International Conference on Indium Phosphide and Related Materials (22nd) (IPRM) held on 31 May-4 Jun 2010, at Takamatsu Symbol Tower, Kagawa, Japan

DTIC Science & Technology

2010-08-13

and S. Bollaert ANODE & EPIPHY groups IEMN, UMR CNRS 8520 Villeneuve d’Ascq. France aiirelicn.olivierV/’ed.univ-lillel .IV F. Martin . O...Desplats CEA / LETI Grenoble. France J. Saint- Martin . M. Shi IEF. UMR CNRS 8622 Orsay. France Y. Wang. M.P. Chauvat, P. Rutcrana CIMAP. UMR CNRS 8252...efficiency Network Device Project" which PETRA contracted with New Energy and Industrial Technology Development Organization (NEDO). V. Summary References

LPHYS'14: 23rd International Laser Physics Workshop (Sofia, Bulgaria, 14-18 July 2014)

NASA Astrophysics Data System (ADS)

Yevseyev, Alexander V.

2014-04-01

The 23rd annual International Laser Physics Workshop (LPHYS14) will be held from 14 July to 18 July 2014 in the city of Sofia, Bulgaria, at the Ramada Sofia Hotel hosted this year by the Institute of Electronics, Bulgarian Academy of Sciences. LPHYS14 continues a series of workshops that took place in Dubna,1992; Dubna/Volga river tour, 1993; New York, 1994; Moscow/Volga river tour (jointly with NATO SILAP Workshop), 1995; Moscow, 1996; Prague, 1997; Berlin, 1998; Budapest, 1999; Bordeaux, 2000; Moscow, 2001; Bratislava, 2002; Hamburg, 2003; Trieste, 2004; Kyoto, 2005; Lausanne, 2006; Len, 2007; Trondheim, 2008; Barcelona, 2009; Foz do Iguau, 2010; Sarajevo, 2011; Calgary, 2012 and Prague, 2013. The total number of participants this year is expected to be about 400. In the past, annual participation was typically from over 30 countries. 2014 Chairpersons Sanka Gateva (Bulgaria), Pavel Pashinin (Russia) LPHYS14 will offer eight scientific section seminars and one general symposium: Seminar 1 Modern Trends in Laser Physics Seminar 2 Strong Field and Attosecond Physics Seminar 3 Biophotonics Seminar 4 Physics of Lasers Seminar 5 Nonlinear Optics and Spectroscopy Seminar 6 Physics of Cold Trapped Atoms Seminar 7 Quantum Information Science Seminar 8 Fiber Optics Symposium Extreme Light Technologies, Science and Applications Abstract of your presentation A one-page abstract should contain: title; list of all co-authors (the name of the speaker underlined); affiliations; correspondence addresses including phone numbers, fax numbers, e-mail addresses; and the text of the abstract. Abstracts should be sent to the following co-chairs of the scientific seminars and the symposium: Kirill A Prokhorov (Seminar 1) E-mail: cyrpro@gpi.ru Mikhail V Fedorov (Seminar 2) E-mail: fedorov@ran.gpi.ru Sergey A Gonchukov (Seminar 3) E-mail: gonchukov@mephi.ru Ivan A Shcherbakov (Seminar 4) E-mail: gbufetova@lsk.gpi.ru Vladimir A Makarov (Seminar 5) E-mail: makarov@msu.ilc.edu.ru Vyacheslav

78 FR 12407 - Self-Regulatory Organizations; ICE Clear Credit LLC; Order Approving Proposed Rule Change To Add...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-22

... SAINT-GOBAIN; Deutsche Telekom AG; FRANCE TELECOM; GAS NATURAL SDG, S.A.; GDF SUEZ; HELLENIC... Telecom International Finance B.V.; RWE Aktiengesellschaft; TELECOM ITALIA SPA; TELEFONICA, S.A.; Telekom...

[Epidemiology of induced abortion in France].

PubMed

Vigoureux, S

2016-12-01

Conduct a synthesis of existing knowledge about the frequency of induced abortion or termination of pregnancy and unplanned pregnancies, the exposure factors of unplanned pregnancies and abortion and the associated morbidity and mortality. Consultation of The Medline database, and national and international reports on abortions in France and in developed countries. Voluntary termination of pregnancy is an induced abortion, opted for non-medical reasons, which in France can be performed before 14 weeks of gestation. Abortion is a common procedure, with rare complications, amounting to about 220,000 procedures per year in France with a stable rate over decades. Similarly to births, women aged 20 to 24 are most affected. The possibility of an abortion exists for all women; this potential event, however, is not equal for each and varies by age of women, socio-professional situations, geographical origins, marital status and past or present domestic and sexual violence. The French historical analysis shows that for 50 years the increase in contraceptive prevalence rate is associated with a decrease in the frequency of unplanned pregnancies. It is therefore possible that the prevention of unplanned pregnancy through early uptake of contraception and contraception options by women is related to a woman's lifestyle. Nonetheless, the number of abortion remains stable since its decriminalization despite the large increase in medicalized contraceptive prevalence rate. Good knowledge of the epidemiology of voluntary termination of pregnancy and unplanned pregnancies is a prerequisite to better adopt prevention and case management strategies. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Disclosure of HIV Status Beyond Sexual Partners by People Living with HIV in France: A Call for Help? Results from the National Cross-Sectional Survey ANRS-VESPA2.

PubMed

Marcellin, Fabienne; Suzan-Monti, Marie; Vilotitch, Antoine; Sagaon-Teyssier, Luis; Mora, Marion; Dray-Spira, Rosemary; Préau, Marie; Lert, France; Spire, Bruno

2017-01-01

HIV status disclosure remains a complex issue for most people living with HIV (PLWH). We analyzed PLWH disclosure behaviors in France, where treatment is free and where the social image of HIV has improved in the general population. Analyses focused on disclosure to the social network excluding sexual partners (close family, other relatives, friends, colleagues). The study sample comprised 3016 participants from the nationally representative survey ANRS-VESPA2. Three PLWH clusters were identified using hierarchical classification ("high disclosure level": 28.2 %, "medium disclosure level": 27.5 %, and "low disclosure level": 44.3 %). In multivariable analyses, the variable "not living in a couple but psychological social support needed" was independently associated with medium (AOR [95 % CI] 1.8 [1.4; 2.3]) and high levels of disclosure (1.4 [1.1; 1.8]) (multinomial regression models). For PLWH living alone, HIV status disclosure may reveal a need for psychological social support, a key component to treatment adherence and positive prevention.

The clinical use of a P63/cytokeratin7/18/cytokeratin5/14 antibody cocktail in diagnostic breast pathology.

PubMed

Reisenbichler, Emily S; Ross, John R; Hameed, Omar

2014-12-01

An antibody cocktail directed against p63, cytokeratin (CK)5/14, and CK7/18 is reported to be useful in distinguishing noninvasive from invasive breast lesions and for the characterization of intraductal epithelial proliferations. However, limited studies evaluate its use in clinical practice. A retrospective review of breast material at a university medical center identified cases that were immunostained with the above antibody cocktail. Additional p63 immunostaining alone was performed to further determine the utility of the antibody cocktail in the evaluation of invasion. Of 50 breast cases identified, the antibody cocktail was used to confirm or exclude invasion in 44 (88%). Twenty-two (50%) of these had easily identifiable p63/CK5/14-positive myoepithelial cells, whereas the remainder lacked such staining, confirming the diagnosis of invasive carcinoma. In 27 cases with available diagnostic material for additional p63 immunostaining, the cocktail better highlighted myoepithelial cells by staining nuclei and cytoplasm. Easier identification of invasion was also facilitated by CK7/18 expression in invasive foci, especially those composed of single cells. Ten cases were immunostained to help determine the nature of an intraductal proliferation. The cocktail demonstrated a mosaic staining pattern of both CK7/18- and CK5/14-positive epithelial cells in 3 (30%) cases consistent with usual hyperplasia; homogenous CK7/18 expression in the remaining cases supported the diagnosis of atypical ductal hyperplasia or carcinoma in situ. In summary, the p63/CK7/18/CK5/14 cocktail stain appears to be a useful tool in diagnostic breast pathology, in the evaluation of possible invasion, particularly in the setting of minute foci of invasion as well as in epithelial proliferations. Copyright © 2014 Elsevier Inc. All rights reserved.

Co-expression of the transcription factors CEH-14 and TTX-1 regulates AFD neuron-specific genes gcy-8 and gcy-18 in C. elegans.

PubMed

Kagoshima, Hiroshi; Kohara, Yuji

2015-03-15

A wide variety of cells are generated by the expression of characteristic sets of genes, primarily those regulated by cell-specific transcription. To elucidate the mechanism regulating cell-specific gene expression in a highly specialized cell, AFD thermosensory neuron in Caenorhabditis elegans, we analyzed the promoter sequences of guanylyl cyclase genes, gcy-8 and gcy-18, exclusively expressed in AFD. In this study, we showed that AFD-specific expression of gcy-8 and gcy-18 requires the co-expression of homeodomain proteins, CEH-14/LHX3 and TTX-1/OTX1. We observed that mutation of ttx-1 or ceh-14 caused a reduction in the expression of gcy-8 and gcy-18 and that the expression was completely lost in double mutants. This synergy effect was also observed with other AFD marker genes, such as ntc-1, nlp-21and cng-3. Electrophoretic mobility shift assays revealed direct interaction of CEH-14 and TTX-1 proteins with gcy-8 and gcy-18 promoters in vitro. The binding sites of CEH-14 and TTX-1 proteins were confirmed to be essential for AFD-specific expression of gcy-8 and gcy-18 in vivo. We also demonstrated that forced expression of CEH-14 and TTX-1 in AWB chemosensory neurons induced ectopic expression of gcy-8 and gcy-18 reporters in this neuron. Finally, we showed that the regulation of gcy-8 and gcy-18 expression by ceh-14 and ttx-1 is evolutionally conserved in five Caenorhabditis species. Taken together, ceh-14 and ttx-1 expression determines the fate of AFD as terminal selector genes at the final step of cell specification. Copyright © 2015 Elsevier Inc. All rights reserved.

Application of Artificial Intelligence For Euler Solutions Clustering

NASA Astrophysics Data System (ADS)

Mikhailov, V.; Galdeano, A.; Diament, M.; Gvishiani, A.; Agayan, S.; Bogoutdinov, Sh.; Graeva, E.; Sailhac, P.

Results of Euler deconvolution strongly depend on the selection of viable solutions. Synthetic calculations using multiple causative sources show that Euler solutions clus- ter in the vicinity of causative bodies even when they do not group densely about perimeter of the bodies. We have developed a clustering technique to serve as a tool for selecting appropriate solutions. The method RODIN, employed in this study, is based on artificial intelligence and was originally designed for problems of classification of large data sets. It is based on a geometrical approach to study object concentration in a finite metric space of any dimension. The method uses a formal definition of cluster and includes free parameters that facilitate the search for clusters of given proper- ties. Test on synthetic and real data showed that the clustering technique successfully outlines causative bodies more accurate than other methods of discriminating Euler solutions. In complicated field cases such as the magnetic field in the Gulf of Saint Malo region (Brittany, France), the method provides geologically insightful solutions. Other advantages of the clustering method application are: - Clusters provide solutions associated with particular bodies or parts of bodies permitting the analysis of different clusters of Euler solutions separately. This may allow computation of average param- eters for individual causative bodies. - Those measurements of the anomalous field that yield clusters also form dense clusters themselves. The application of cluster- ing technique thus outlines areas where the influence of different causative sources is more prominent. This allows one to focus on areas for reinterpretation, using different window sizes, structural indices and so on.

Quantitative and qualitative estimates of cross-border tobacco shopping and tobacco smuggling in France.

PubMed

Lakhdar, C Ben

2008-02-01

In France, cigarette sales have fallen sharply, especially in border areas, since the price increases of 2003 and 2004. It was proposed that these falls were not due to people quitting smoking but rather to increased cross-border sales of tobacco and/or smuggling. This paper aims to test this proposition. Three approaches have been used. First, cigarette sales data from French sources for the period 1999-2006 were collected, and a simulation of the changes seen within these sales was carried out in order to estimate what the sales situation would have looked like without the presence of foreign tobacco. Second, the statements regarding tobacco consumed reported by the French population with registered tobacco sales were compared. Finally, in order to identify the countries of origin of foreign tobacco entering France, we collected a random sample of cigarette packs from a waste collection centre. According to the first method, cross-border shopping and smuggling of tobacco accounted for 8635 tones of tobacco in 2004, 9934 in 2005, and 9930 in 2006, ie, between 14% and 17% of total sales. The second method gave larger results: the difference between registered cigarette sales and cigarettes declared as being smoked was around 12,000 to 13,000 tones in 2005, equivalent to 20% of legal sales. The collection of cigarette packs at a waste collection centre showed that foreign cigarettes accounted for 18.6% of our sample in 2005 and 15.5% in 2006. France seems mainly to be a victim of cross-border purchasing of tobacco products, with the contraband market for tobacco remaining modest. in order to avoid cross-border purchases, an increased harmonization of national policies on the taxation of tobacco products needs to be envisaged by the European Union.

Prayer to the Saints or the Virgin and Health among Older Mexican Americans

ERIC Educational Resources Information Center

Krause, Neal; Bastida, Elena

2011-01-01

The purpose of this study was to evaluate a conceptual model that assesses whether praying to the saints or the Virgin is associated with the health of older Mexican Americans. A survey was conducted of 1,005 older Mexican Americans (Mean age = 73.9 years; SD = 6.6 years). Data from 795 of the Catholic respondents are presented in this study. The…

Ciguatera fish poisoning in an international ship crew in Saint John Canada: 2015.

PubMed

Muecke, C; Hamper, L; Skinner, A L; Osborne, C

2015-11-05

An international ship crew presented for medical care in Saint John, New Brunswick, following rapid onset of gastrointestinal and in some cases neurological and cardiac symptoms after a common fish meal. Ciguatera poisoning was identified as the cause of illness. This report describes the public health investigation and management of this incident, including collaboration between the implicated provincial and federal authorities.

Ciguatera fish poisoning in an international ship crew in Saint John Canada: 2015

PubMed Central

Muecke, C; Hamper, L; Skinner, AL; Osborne, C

2015-01-01

An international ship crew presented for medical care in Saint John, New Brunswick, following rapid onset of gastrointestinal and in some cases neurological and cardiac symptoms after a common fish meal. Ciguatera poisoning was identified as the cause of illness. This report describes the public health investigation and management of this incident, including collaboration between the implicated provincial and federal authorities. PMID:29769923

A second level of the Saint Petersburg skyline

NASA Astrophysics Data System (ADS)

Krasnopolsky, Andrey; Bolotin, Sergey

2018-03-01

The article considers the history of the residential development in Saint Petersburg and states corresponding landmark dates. In recent years, changes in the altitude range of the residential development are noted, the influence of this factor on the formation of the city's silhouette is assessed. Reasons for such changes are identified. Attractiveness of high-rise residential complexes for living is assessed. Conclusions are made of tendencies in further housing construction development in terms of its altitude range. It is noted that it is possible to locate multi-storied buildings in the periphery of the city, taking into account specific visual characteristics of the construction site and silhouette of erected buildings; as for central districts, strict regulations regarding the altitude range are needed.

Floods in southwest-central Florida from hurricane Frances, September 2004

USGS Publications Warehouse

Kane, Richard L.

2005-01-01

Hurricane Frances brought heavy rainfall and widespread flooding to southwest-central Florida September 4-14, 2004. The center of Hurricane Frances made landfall on the east coast of Florida on September 5 as a category 2 hurricane on the Saffir-Simpson scale, then moved west-northwestward through central Florida before exiting Pasco County into the Gulf of Mexico on September 6 (fig. 1; National Weather Service, 2004). The hurricane moved across the Florida Peninsula generating 5 to 11 inches of rain over already saturated ground (table 1). Record flooding occurred in parts of Hardee, Hillsborough, Pasco, and Polk Counties (fig. 1). The hurricane and resulting floods caused an estimated $4-5 billion in damage to public and private property (Harrington, 2004), and 23 deaths were attributed to Hurricane Frances (National Weather Service, 2004). Several watersheds drain counties in southwest-central Florida that were affected by Hurricane Frances. De Soto, Hardee, and Polk Counties generally are drained by the Peace River system, which flows southwestward to Charlotte Harbor and the Gulf of Mexico. Hillsborough and Pasco Counties generally are drained by the Alafia, Hillsborough, Anclote, and Pithlachascotee River systems. Water in the Hillsborough and Alafia River watersheds flows west to Tampa Bay and water in the Anclote and Pithlachascotee River watersheds flows west to the Gulf of Mexico. (fig. 1, http://water.usgs.gov/pubs/fs/2005/3028/#fig1).

Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5

PubMed Central

Henry, Margit; Rotshteyn, Tamara; Brunn, Anna; Carstov, Mariana; Deckert, Martina; Hescheler, Jürgen; Sachinidis, Agapios; Pfitzer, Gabriele

2018-01-01

In skeletal muscle the coordinated actions of two mechanically coupled Ca2+ channels—the 1,4-dihydropyridine receptor (Cav1.1) and the type 1 ryanodine receptor (RYR1)–underlie the molecular mechanism of rapid cytosolic [Ca2+] increase leading to contraction. While both [Ca2+]i and contractile activity have been implicated in the regulation of myogenesis, less is known about potential specific roles of Cav1.1 and RYR1 in skeletal muscle development. In this study, we analyzed the histology and the transcriptomic changes occurring at E14.5 –the end of primary myogenesis and around the onset of intrauterine limb movement, and at E18.5 –the end of secondary myogenesis, in WT, RYR1-/-, and Cav1.1-/- murine limb skeletal muscle. At E14.5 the muscle histology of both mutants exhibited initial alterations, which became much more severe at E18.5. Immunohistological analysis also revealed higher levels of activated caspase-3 in the Cav1.1-/- muscles at E14.5, indicating an increase in apoptosis. With WT littermates as controls, microarray analyses identified 61 and 97 differentially regulated genes (DEGs) at E14.5, and 493 and 1047 DEGs at E18.5, in RYR1-/- and Cav1.1-/- samples, respectively. Gene enrichment analysis detected no overlap in the affected biological processes and pathways in the two mutants at E14.5, whereas at E18.5 there was a significant overlap of DEGs in both mutants, affecting predominantly processes linked to muscle contraction. Moreover, the E18.5 vs. E14.5 comparison revealed multiple genotype-specific DEGs involved in contraction, cell cycle and miRNA-mediated signaling in WT, neuronal and bone development in RYR1-/-, and lipid metabolism in Cav1.1-/- samples. Taken together, our study reveals discrete changes in the global transcriptome occurring in limb skeletal muscle from E14.5 to E18.5 in WT, RYR1-/- and Cav1.1-/- mice. Our results suggest distinct functional roles for RYR1 and Cav1.1 in skeletal primary and secondary myogenesis. PMID

A Worked Example of an Application of the Saint Simulation Program.

DTIC Science & Technology

1987-09-01

tApprove foX pu bldc L-- -’ -:,=* J Approved for public release. This work is copyright. Apart from any fair dealing for the purpose of study, research...this network are 1. there are three types of incoming messages, 2. the rate of message generation is varied between two limits and is controlled by the...SAINT controlling program, and 3. the whole scenario is run for a fixed period of time itim limit). These features were included on the basis of

High-rise construction in the Saint Petersburg agglomeration in 1703-1950s

NASA Astrophysics Data System (ADS)

Sementsov, Sergey; Akulova, Nadezhda; Kurakina, Severina

2018-03-01

Regularities of high-rise construction (implemented projects and developments) in Saint Petersburg and the Saint Petersburg agglomeration since the foundation of the city in 1703 till the 1950s are considered. Based on these regularities, a single spatially developed system of vertical dominants is formed. High-rise construction in the city and its suburbs started in the 1710s and continues up to the present time. In the considered decades (1703-1950s), high-rise construction mostly performed urban-planning functions (with vertical and symbolic dominants), relying on patterns of the visual perception of man-made landscapes under development. Since the 1710s, the construction of vertical dominants (mainly temples, spires of towers, lighthouses, etc.) of five ranks (depending on the altitude range and in relation to the background development) was conducted in territories of the entire agglomeration. These dominants were arranged in landscapes of the city and suburbs with almost mathematically precise accuracy and according to special regulations. Such dominants obtained particular descriptive and silhouette characteristics in accordance with the conditions of spatial perception. In some periods of city development, attempts were made to create monuments (symbolic dominants) of specific height and include those in the spatial system of high-rise dominants as significant elements of the city silhouette.

Symposium on Applications and the Internet (SAINT 2003) Proceedings (Orlando, Florida, January 27-31, 2003).

ERIC Educational Resources Information Center

Helal, Sumi, Ed.; Oie, Yuji, Ed.; Chang, Carl, Ed.; Murai, Jun, Ed.

This proceedings from the 2003 Symposium on Applications and the Internet (SAINT) contains papers from sessions on: (1) mobile Internet, including a target-driven cache replacement policy, context-awareness for service discovery, and XML transformation; (2) collaboration technology I, including human-network-based filtering, virtual collaboration…

PREFACE: 1st International School and Conference "Saint Petersburg OPEN 2014" on Optoelectronics, Photonics, Engineering and Nanostructures

NASA Astrophysics Data System (ADS)

2014-09-01

Dear Colleagues, 1st International School and Conference "Saint Petersburg OPEN 2014" on Optoelectronics, Photonics, Engineering and Nanostructures was held on March 25 - 27, 2014 at St. Petersburg Academic University - Nanotechnology Research and Education Centre of the Russian Academy of Sciences. The School and Conference included a series of invited talks given by leading professors with the aim to introduce young scientists with actual problems and major advances in physics and technology. The keynote speakers were: Mikhail Glazov (Ioffe Physico-Technical Institute RAS, Russia) Vladimir Dubrovskii (Saint Petersburg Academic University RAS, Russia) Alexey Kavokin (University of Southampton, United Kingdom and St. Petersburg State University, Russia) Vladimir Korenev (Ioffe Physico-Technical Institute RAS, Russia) Sergey Kukushkin (Institute of Problems of Mechanical Engineering RAS, Russia) Nikita Pikhtin (Ioffe Physico-Technical Institute RAS, Russia and "Elfolum" Ltd., Russia) Dmitry Firsov (Saint Petersburg State Polytechnical University, Russia) During the poster session all undergraduate and graduate students attending the conference presented their works. Sufficiently large number of participants with more than 160 student attendees from all over the world allowed the Conference to provide a fertile ground for the fruitful discussions between the young scientists as well as to become a perfect platform for the valuable discussions between student authors and highly experienced scientists. The best student papers, which were selected by the Program Committee and by the invited speakers basing on the theses and their poster presentation, were awarded with diplomas of the conference - see the photos. This year's School and Conference is supported by SPIE (The International Society for Optics and Photonics), OSA (The Optical Society), St. Petersburg State Polytechnical University and by Skolkovo Foundation. It is a continuation of the annual schools and

21 CFR 73.3119 - 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 1 2014-04-01 2014-04-01 false 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone. 73.3119 Section 73.3119 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Medical Devices § 73.3119 7...

21 CFR 73.3119 - 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 1 2012-04-01 2012-04-01 false 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone. 73.3119 Section 73.3119 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Medical Devices § 73.3119 7...

21 CFR 73.3119 - 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 1 2013-04-01 2013-04-01 false 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone. 73.3119 Section 73.3119 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Medical Devices § 73.3119 7...

21 CFR 73.3119 - 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone. 73.3119 Section 73.3119 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Medical Devices § 73.3119 7...

21 CFR 73.3119 - 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 1 2011-04-01 2011-04-01 false 7,16-Dichloro-6,15-dihydro-5,9,14,18-anthrazinetetrone. 73.3119 Section 73.3119 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Medical Devices § 73.3119 7...

Rainfall and cave water isotopic relationships in two South-France sites

NASA Astrophysics Data System (ADS)

Genty, D.; Labuhn, I.; Hoffmann, G.; Danis, P. A.; Mestre, O.; Bourges, F.; Wainer, K.; Massault, M.; Van Exter, S.; Régnier, E.; Orengo, Ph.; Falourd, S.; Minster, B.

2014-04-01

This article presents isotopic measurements (δ18O and δD) of precipitation and cave drip water from two sites in southern France in order to investigate the link between rainfall and seepage water, and to characterize regional rainfall isotopic variability. These data, which are among the longest series in France, come from two rainfall stations in south-west France (Le Mas 1996-2012, and Villars 1998-2012; typically under Atlantic influence), and from one station in the south-east (Orgnac 2000-2012; under both Mediterranean and Atlantic influence). Rainfall isotopic composition is compared to drip water collected under stalactites from the same sites: Villars Cave (four drip stations 1999-2012) in the south-west, and Chauvet Cave (two drip stations 2000-2012) in the south-east, near Orgnac. The study of these isotopic data sets allows the following conclusions to be drawn about the rainfall/drip water relationships and about rainfall variability: (1) the cave drip water isotopic composition does not show any significant changes since the beginning of measurements; in order to explain its isotopic signature it is necessary to integrate weighted rainfall δ18O of all months during several years, which demonstrates that, even at shallow depths (10-50 m), cave drip water is a mixture of rain water integrated over relatively long periods, which give an apparent time residence from several months to up to several years. These results have important consequences on the interpretation of proxies like speleothem fluid inclusions and tree-ring cellulose isotopic composition, which are used for paleoclimatic studies; (2) in the Villars Cave, where drip stations at two different depths were studied, lower δ18O values were observed in the lower galleries, which might be due to winter season overflows during infiltration and/or to older rain water with a different isotopic composition that reaches the lower galleries after years; (3) local precipitation is characterized by

75 FR 65222 - Airworthiness Directives; Eurocopter France Model AS 350 B, BA, B1, B2, B3, and D, and Model...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

... Airworthiness Directives; Eurocopter France Model AS 350 B, BA, B1, B2, B3, and D, and Model AS355 E, F, F1, F2... adopting a new airworthiness directive (AD) for the Eurocopter France Model AS 350 B, BA, B1, B2, B3, and D... 14 CFR part 39 to include an AD that would apply to the Eurocopter France Model AS 350 B, BA, B1, B2...

Stray Dogs, Saints, and Saviors: Fighting for the Soul of America's Toughest High School

ERIC Educational Resources Information Center

Russo, Alexander

2011-01-01

This book tells the real-life story of Locke High School. Locke High--originally known for its excellence--became one of the toughest, most dysfunctional schools in the nation. Then in 2007 teachers voted to bring in an upstart charter school organization called "Green Dot" to try and restore the Locke Saints' past glory. It was a brave…

Sex Discrimination at Saint Ambrose University: The Moral and Legal Consequences of Unethical Behavior

ERIC Educational Resources Information Center

Martin, Jennifer; Beese, Jane A.

2015-01-01

This case was developed for use in a learning-centered course with a focus on administrative leadership and ethical behavior. This case describes the experience of a new faculty member at Saint Ambrose University, as she discovers a wide range of ethical and management problems in her department. The case unfolds as we track her efforts to deal…

78 FR 9940 - Naugatuck Valley Surgical Center, Department of Saint Mary's Hospital, Waterbury, CT: Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-12

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-82,137] Naugatuck Valley Surgical Center, Department of Saint Mary's Hospital, Waterbury, CT: Notice of Affirmative Determination... application, I conclude that the claim is of sufficient weight to justify reconsideration of the U.S...

Nure aerial gamma-ray and magnetic reconnaissance survey: Chugach/Yakutat area, Alaska, Mt. Saint Elias Quadrangle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1978-10-01

Volume II contains the following data on Mt. Saint Elias, Alaska: geologic base map, flight path map, anomaly maps (U, Th, K, UlTh, UlK, ThlK), radiometric multiple-parameter stacked profiles, magnetic and ancillary profile data, and statistical data. (LK)

Theories about sex and sexuality in utopian socialism.

PubMed

Poldervaart, S

1995-01-01

It was the utopian socialists of the period 1800-50 (Fourier, Saint-Simon, and the Saint-Simonians in France, as well as the Owenites in Great Britain) who not only challenged the imperialism of reason but sought to rehabilitate the flesh by valuing its pleasure and incentives. Sex and sexuality were central issues for the first socialists, who were scorned as "utopian" by Marx and Engels for seeking to improve the status of all members of society through peaceful means. Because Marxism has played a greater role in the history of socialism, the utopian socialist discussions have been largely disregarded. This essay analyzes the works of the utopian socialists Fourier, Saint-Simon, and the Saint-Simonians, arguing that resurgences of the utopian socialist tradition can be discerned around 1900 and again circa 1970.

Research, methodology, and applications of probabilistic seismic-hazard mapping of the Central and Eastern United States; minutes of a workshop on June 13-14, 2000, at Saint Louis University

USGS Publications Warehouse

Wheeler, Russell L.; Perkins, David M.

2000-01-01

The U.S. Geological Survey (USGS) is updating and revising its 1996 national seismic-hazard maps for release in 2001. Part of this process is the convening of four regional workshops with earth scientists and other users of the maps. The second of these workshops was sponsored by the USGS and the Mid-America Earthquake Center, and was hosted by Saint Louis University on June 13-14, 2000.The workshop concentrated on the central and eastern U.S. (CEUS) east of the Rocky Mountains. The tasks of the workshop were to (1) evaluate new research findings that are relevant to seismic hazard mapping, (2) discuss modifications in the inputs and methodology used in the national maps, (3) discuss concerns by engineers and other users about the scientific input to the maps and the use of the hazard maps in building codes, and (4) identify needed research in the CEUS that can improve the seismic hazard maps and reduce their uncertainties. These minutes summarize the workshop discussions. This is not a transcript; some individual remarks and short discussions of side issues and logistics were omitted. Named speakers were sent a draft of the minutes with a request for corrections of any errors in remarks attributed to them. Nine people returned corrections, amplifications, or approvals of their remarks as reported. The rest of this document consists of the meeting agenda, discussion summaries, and a list of the 60 attendees.

[Anesthesiologists in France].

PubMed

Mizuno, Ju; Hanaoka, Kazuo; Merckx, Paul; Bonneville, Claire Tae; Kavafyan, Juliette; Mantz, Jean

2007-03-01

We review some anesthesiologist's curriculum and demographic characteristics in France to the community of Japanese anesthesiologists. To become a certified anesthesiologist and an intensive care physician currently requires six years' medical education, passing national medical examination, and five years' special training as an intern of anesthesiology and intensive care. This educational course was started in 1984. There are 7942 certified anesthesiologists in France in 1999. The average age is 45.9 years and the ratio of female is 35.3%. Approximately two thirds of certified anesthesiologists are working in public institutions. 89% is full-time workers. More than half of certified anesthesiologists actually participate in daily intensive care practice. The number of certified anesthesiologists has been increasing gradually totaling 10,062 persons in 2005. The number of certified anesthesiologists per ten thousands general population is 1.7 persons and the corresponding ratio to all medical doctors is 4.8%. Working hours and holidays are regulated by the French Labour Law. The anaesthesiologist often works in a team with a nurse anaesthetist. The number of certified anesthesiologists in France is larger than that in Japan. Management of anesthesia in France seems to have an advantage in manpower.

Assessment of undiscovered oil and gas resources of the Paris Basin, France, 2015

USGS Publications Warehouse

Schenk, Christopher J.; Charpentier, Ronald R.; Klett, Timothy R.; Tennyson, Marilyn E.; Mercier, Tracey J.; Le, Phoung A.; Brownfield, Michael E.; Pitman, Janet K.; Gaswirth, Stephanie B.; Marra, Kristen R.; Leathers, Heidi M.

2015-01-01

Using a geology-based assessment methodology, the U.S. Geological Survey estimated means of 222 million barrels of unconventional oil; 2,092 billion cubic feet of unconventional gas; 18 million barrels of conventional oil; and 47 billion cubic feet of conventional gas resources in the Paris Basin of France.

Incidence of solitary pulmonary nodules in Northeastern France: a population-based study in five regions.

PubMed

Marrer, Émilie; Jolly, Damien; Arveux, Patrick; Lejeune, Catherine; Woronoff-Lemsi, Marie-Christine; Jégu, Jérémie; Guillemin, Francis; Velten, Michel

2017-01-11

The discovery of a solitary pulmonary nodule (SPN) on a chest imaging exam is of major clinical concern. However, the incidence rates of SPNs in a general population have not been estimated. The objective of this study was to provide incidence estimates of SPNs in a general population in 5 northeastern regions of France. This population-based study was undertaken in 5 regions of northeastern France in May 2002-March 2003 and May 2004-June 2005. SPNs were identified by chest CT reports collected from all radiology centres in the study area by trained readers using a standardised procedure. All reports for patients at least 18 years old, without a previous history of cancer and showing an SPN between 1 and 3 cm, were included. A total of 11,705 and 20,075 chest CT reports were collected for the 2002-2003 and 2004-2005 periods, respectively. Among them, 154 and 297 reports showing a SPN were included, respectively for each period. The age-standardised incidence rate (IR) was 10.2 per 100,000 person-years (95% confidence interval 8.5-11.9) for 2002-2003 and 12.6 (11.0-14.2) for 2004-2005. From 2002 to 2005, the age-standardised IR evolved for men from 16.4 (13.2-19.6) to 17.7 (15.0-20.4) and for women from 4.9 (3.2-6.6) to 8.2 (6.4-10.0). In multivariate Poisson regression analysis, gender, age, region and period were significantly associated with incidence variation. This study provides reference incidence rates of SPN in France. Incidence was higher for men than women, increased with age for both gender and with time for women. Trends in smoking prevalence and improvement in radiological equipment may be related to incidence variations.

Great artists with rheumatoid arthritis. What did their disease and coping teach? Part II. Raoul Dufy and Niki de Saint Phalle.

PubMed

Zeidler, Henning

2012-12-01

Raoul Dufy (1877-1953) and Niki de Saint Phalle (1930-2002) were 2 famous artists who suffered from rheumatoid arthritis (RA). Both artists represent an additional outstanding example of successful coping with RA in former times when, for the first time, corticosteroids were available, but nevertheless treatment was very limited in the pre-biological era. Dufy was one of the earliest patients with RA who received corticosteroids and regained his creativity to paint for a few additional years, but finally he died of massive intestinal hemorrhages, the adverse event of the combination of corticosteroid plus aspirin. Niki de Saint Phalle, a self-taught French painter and sculptor, was one of the most significant and unconventional female artists of the 20th century. Her eventful life was full of emotional burdens and lifelong lung disease in addition to RA. Niki de Saint Phalle came out from each physical and emotional crisis with new forces and new artistic ideas. Interestingly, it has been suggested that the occupational exposure to colors contributed to the development of RA in artists, which used significantly more bright and clear colors based on toxic heavy metals such as Renoir and Dufy. Moreover, these 2 were cigarette smokers, a recently described risk factor for developing RA and increasing the severity once it does develop. Niki de Saint Phalle produced her sculptures made of plastic material without protection while she assumed that exposition to polyester and toxic fumes of polystyrene caused severe damage to her lungs, resulting in recurrent health problems.

Re-Emergence of Bluetongue Virus Serotype 8 in France, 2015.

PubMed

Sailleau, C; Bréard, E; Viarouge, C; Vitour, D; Romey, A; Garnier, A; Fablet, A; Lowenski, S; Gorna, K; Caignard, G; Pagneux, C; Zientara, S

2017-06-01

At the end of August 2015, a ram located in central France (department of Allier) showed clinical signs suggestive of BTV (Bluetongue virus) infection. However, none of the other animals located in the herd showed any signs of the Bluetongue disease. Laboratory analyses identified the virus as BTV serotype 8. The viro and sero prevalence intraherd were 2.4% and 8.6% in sheep and 18.3% and 42.9% in cattle, respectively. Phylogenetic studies showed that the sequences of this strain are closely related to another BTV-8 strain that has circulated in France in 2006-2008. The origin of the outbreak is unclear but it may be assumed that the BTV-8 has probably circulated at very low prevalence (possibly in livestock or wildlife) since its first emergence in 2007-2008. © 2015 Blackwell Verlag GmbH.

Finding the lost arches of the Medieval Avignon's Bridge (Avignon, Provence, South France): a geoarchaeological approach

NASA Astrophysics Data System (ADS)

Ghilardi, M.; Vella, M. A.; Hermitte, D.; Parisot, J. C.; Dussouillez, P.; Fleury, T. J.; Provansal, M.; Delanghe-Sabatier, D.; Demory, F.; Mathé, P. E.; Quesnel, Y.; Danos, S.; Balossino, S.; Delpey, Y.; Hartmann-Virnich, A.; Berthelot, M.

2012-04-01

This papers aims to precisely locate the medieval arches of the so called Avignon's (Saint Bénézet) Bridge (South France) and to reconstruct the fluvial dynamics of the Rhone River from Early Medieval Times to the 19th century. Until now, just four remnant arches are still visible (near Avignon) and it is estimated that 22 arches (which represents a total length of approximately 920 meters) were built to span over one of the largest French Rivers. The late roman and early mediaeval dates of several foundation poles extracted from the river bed might suggest the existence of an earlier bridge, though it remains uncertain if any of such an earlier structure was still visible when the first mediaeval bridge was built. The mediaeval bridge was erected from 1177 until 1185 (in less than 10 years), but modified a few decades later when stone arches were erected, thus raising the road level substantially. The structure of the bridge being vulnerable, seasonal floods proved a neverending threat and cause of damage which was frequently repaired with masonry or wood. Final abandon of the edifice could be placed in the late 1660s - Early 1670s according to historical sources. Questions arose about the location of the "lost arches" and evident flood events dated back to the Little Ice Age (e.g. 1500 to 1850) could be responsible of the partial destruction of the bridge. Few archaeological, architectural, historical and palaeoenvironmental works have been undertaken in order to determine the precise shape of the Saint Bénézet Bridge at certain stages of its history. Since 2010, a joint team composed by laboratories affiliated to the French Public Research Centre (CNRS) and to Universities of Avignon and of Aix-Marseille 1 is trying to link the different phases of constructions/destructions of the monument with the fluvial dynamics of the Rhone River for the concerned period (ANR PAVAGE). The geoarchaeological approach adopted comprises bathymetric surveys (SONAR and

Center for Transportation Studies 24th annual transportation research conference, May 22-23, 2013, Saint Paul, Minnesota.

DOT National Transportation Integrated Search

2013-05-01

The University of Minnesotas Center for Transportation : Studies is pleased to present its 24th Annual Transportation : Research Conference, May 22-23, 2013. The conference will : be held at the Saint Paul RiverCentre, 175 West Kellogg : Boulevard...

Cannabis use during pregnancy in France in 2010.

PubMed

Saurel-Cubizolles, M-J; Prunet, C; Blondel, B

2014-07-01

The aim was to estimate the proportion of women who reported cannabis use during pregnancy, to analyse the demographic and social characteristics of users, and the link between cannabis use and either preterm or small-for-gestational-age birth. Data were obtained from interviews of a representative sample of women giving birth in France in 2010 in the days after delivery, and from their medical records. All maternity units in France. The analysis includes women with live singleton births in metropolitan France who responded to the question about cannabis use during pregnancy: in total, 13 545 women. The percentage of cannabis users during pregnancy was estimated, and variations according to social characteristics were described. Logistic regression analyses were used to investigate any associations between cannabis use and preterm birth or small-for-gestational-age status. Percentage of cannabis use, preterm birth rate, and small-for-gestational-age rate. In all, 1.2% of women reported having used cannabis during pregnancy. This percentage was higher among younger women, women living alone, or women who had a low level of education or low income. It was also associated with tobacco use and drinking alcohol. Cannabis users had higher rates of spontaneous preterm births: 6.4 versus 2.8%, for an adjusted odds ratio (aOR) of 2.15 (95% CI 1.10-4.18). The corresponding aOR was 2.64 (95% CI 1.12-6.22) among tobacco smokers and 1.22 (95% CI 0.29-5.06) among non-tobacco smokers. Although the reported rate of cannabis use during pregnancy in France is low, efforts should be continued to inform women and healthcare providers about the potential consequences of its use. © 2014 Royal College of Obstetricians and Gynaecologists.

Reprocessing the Elliptical Orbiting Galileo Satellites E14 and E18: Preliminary Results

NASA Astrophysics Data System (ADS)

Männel, Benjamin

2017-04-01

In August 2014, the two Galileo satellites FOC-1 (E18) and FOC-2 (E14) were - due to a technical problem - launched into a wrong, elliptic orbit. In a recovery mission a series of orbit maneuvers were performed to raise the perigee to an altitude where both spacecrafts could be introduced to the Galileo navigation service. After this period of orbit maintenance both satellites started to transmit navigation signals at November 29, 2014 (E18) and March 17, 2015 (E14). However, as it was not possible to recover the nominal orbits due to propellant limitations, both spacecrafts orbit the Earth with a numerical eccentricity of 0.16 and an inclination of 50.2°. Very soon, it was assumed that both satellites could be highly useful for studies on general relativity, especially as the Galileo spacecrafts are equipped with very stable passive hydrogen masers. A prerequisite for dedicated studies in this field are highly accurate satellite orbits and clock corrections. Preliminary results for orbit and satellite clock determination will be presented based on an initial reprocessing over the past 2.5 years. The presentation focuses firstly on orbit modeling aspects with respect to the elliptically orbits. Secondly the derived clock corrections for the on-board passive clocks are assessed with respect to the reference clock at ground stations. The results will be discussed also with respect to the proposed Galileo-based studies on the gravitational redshift.

Economic burden of advanced melanoma in France, Germany and the UK: a retrospective observational study (Melanoma Burden-of-Illness Study).

PubMed

Grange, Florent; Mohr, Peter; Harries, Mark; Ehness, Rainer; Benjamin, Laure; Siakpere, Obukohwo; Barth, Janina; Stapelkamp, Ceilidh; Pfersch, Sylvie; McLeod, Lori D; Kaye, James A; Wolowacz, Sorrel; Kontoudis, Ilias

2017-12-01

The aim of this study was to estimate the cost-of-illness associated with completely resected stage IIIB/IIIC melanoma with macroscopic lymph node involvement, overall and by disease phase, in France, Germany and the UK. This retrospective observational study included patients aged older than or equal to 18 years first diagnosed with stage IIIB/IIIC cutaneous melanoma between 1 January 2009 and 31 December 2011. Data were obtained from medical records and a patient survey. Direct costs, indirect costs and patient out-of-pocket expenses were estimated in euros (€) (and British pounds, £) by collecting resource use and multiplying by country-specific unit costs. National annual costs were estimated using national disease prevalence from the European cancer registry and other published data. Forty-nine centres provided data on 558 patients (58.2% aged <65 years, 53.6% stage IIIB disease at diagnosis). The mean follow-up duration was 27 months (France), 26 months (Germany) and 22 months (UK). The mean total direct cost per patient during follow-up was €23 582 in France, €32 058 in Germany and €37 970 (£31 123) in the UK. The largest cost drivers were melanoma drugs [mean €14 004, €21 269, €29 750 (£24 385), respectively] and hospitalization/emergency treatment [mean: €6634, €6950, €3449 (£2827), respectively]. The total mean indirect costs per patient were €129 (France), €4,441 (Germany) and €1712 (£1427) (UK). Estimates for annual national direct cost were €13.1 million (France), €30.2 million (Germany) and €27.8 (£22.8) million (UK). The economic burden of stage IIIB/IIIC melanoma with macroscopic lymph node involvement was substantial in all three countries. Total direct costs were the highest during the period with distant metastasis/terminal illness.

A Comparative Case Study of Self-Actualization in Eleanor Roosevelt and Antoine de Saint-Exupery.

ERIC Educational Resources Information Center

Tyska, Cynthia Ann

Eleanor Roosevelt and Antoine de Saint-Exupery are described as strongly developed self-actualizing people. They were selected as subjects of this study because they are generally believed to possess self-actualizing characteristics and because their positions as public figures made it more likely that data on them would be accessible.…

Project Early Kindergarten Evaluation: Results through 2009-10 of a Saint Paul Public Schools Initiative

ERIC Educational Resources Information Center

Maxfield, Jennifer; Gozali-Lee, Edith; Mueller, Dan

2010-01-01

Project Early Kindergarten (PEK) aims to improve the school-readiness of Saint Paul children and help close the achievement gap through offering high-quality educational experiences for preschool children. This report comes at the conclusion of the sixth year of PEK. Following an initial planning year (2004-05), PEK has served children through the…

Psycho-social influences on food choice in Southern France and Central England.

PubMed

Pettinger, C; Holdsworth, M; Gerber, M

2004-06-01

This study used attitudinal scales to investigate the nature of attitudes to diet and health in a northern European country (Central England) and a southern European country (Mediterranean France). Cross-sectional studies were conducted using self-administered postal questionnaires that were distributed simultaneously in April 2001 in Montpellier, France and Nottingham, England. A stratified random sample of 1000 males and 1000 females aged 18-65 years was generated from the electoral roll in each country. The final sample comprised England: n = 826 (58% male and 42% female; mean age=44 years) and France: n = 766 (42% male and 58% female; mean age=42 years). This study has demonstrated that the pleasurable and social aspects of eating, certain food quality issues, as well as health as a value were regarded as priorities by French respondents. On the other hand, English respondents reported that organic and ethical issues and convenience were important factors influencing their food choices. In conclusion, the two populations can be differentiated overall in their attitudes and beliefs to food choice.

Intrauterine contraception in Saint Louis: A Survey of Obstetrician and Gynecologists’ knowledge and attitudes

PubMed Central

Madden, Tessa; Allsworth, Jenifer E.; Hladky, Katherine J.; Secura, Gina M.; Peipert, Jeffrey F.

2009-01-01

Background Many obstacles to intrauterine contraception use exist, including provider and patient misinformation, high upfront cost, and clinician practice patterns. The aim of our study was to investigate knowledge and attitudes about intrauterine contraception among obstetricians and gynecologists in the area of Saint Louis. Study Design We mailed a self-administered, anonymous survey to 250 clinicians who provide obstetric and gynecologic care in Saint Louis City and County which included questions about demographics, training, family planning visits, and intrauterine contraceptive knowledge and use. Results The overall survey response rate among eligible clinicians was 73.7%. Clinicians who had recently finished training or saw higher numbers of contraceptive patients per week were more likely to insert intrauterine contraception than clinicians who completed training prior to 1989 or saw fewer contraceptive patients. Several misconceptions among clinicians were identified, including an association between intrauterine contraceptives and an elevated risk of pelvic inflammatory disease. Conclusions Physician misconceptions about the risks of intrauterine contraception continue to occur. Improved clinician education is greatly needed to facilitate the use of these highly effective, long-acting, reversible methods of contraception. PMID:20103447

18 CFR 16.14 - Departmental recommendation for takeover.

Code of Federal Regulations, 2011 CFR

2011-04-01

... recommendation for takeover. 16.14 Section 16.14 Conservation of Power and Water Resources FEDERAL ENERGY... 15 of the Federal Power Act § 16.14 Departmental recommendation for takeover. (a) A Federal department or agency may file a recommendation that the United States exercise its right to take over a...

18 CFR 16.14 - Departmental recommendation for takeover.

Code of Federal Regulations, 2010 CFR

2010-04-01

... recommendation for takeover. 16.14 Section 16.14 Conservation of Power and Water Resources FEDERAL ENERGY... 15 of the Federal Power Act § 16.14 Departmental recommendation for takeover. (a) A Federal department or agency may file a recommendation that the United States exercise its right to take over a...

[Involuntary psychiatric care for inmates in France: Only for "dangerous" patients?

PubMed

Fovet, T; Bertrand, M; Horn, M; Si Mohammed, W; Dandelot, D; Dalle, M-C; Thomas, P; Amad, A

2017-11-27

The unités hospitalières spécialement aménagées (UHSA) are full-time inpatient psychiatric units for inmates in France. Their creation has been associated with several advances in access to psychiatric care for inmates in recent years. However, there is still only one means of involuntary hospitalization for prisoners in France: care by decision of a representative of the state (les soins sur décision d'un représentant de l'état [SDRE]). Interestingly, for SDRE to be recognized as legal by the French judge, the patient must be "a danger to himself or to the others". Thus, there is a major difference with involuntary hospitalization outside the prison, and there are specific criteria for involuntary psychiatric hospitalization for inmates in France. This situation questions the general framework of involuntary psychiatric care and is very inconsistent with French law. Indeed, the goal of the loi n o  94-43 du 18 janvier 1994 relating to public health and social protection is to ensure equivalent care for all patients, incarcerated or not. Copyright © 2017 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

Continued Optical Sensor Operations in a Laser Environment

DTIC Science & Technology

2011-02-16

CANADA G3J 1X5; cMIPS UHA, 61 rue Albert Camus , Mulhouse, FRANCE 68200, http://pubs.drdc.gc.ca/PDFS/unc00/p533547_A1b.pdf (accessed 16 January 2011...Cassagnou, Saint-Louis, FRANCE 68300; bDRDC-Valcartier, 2459 Pie-XI Blvd North, Quebec, QC, CANADA G3J 1X5; cMIPS UHA, 61 rue Albert Camus , Mulhouse

"The Glory of God Is Intelligence": Exploring the Foundations of Latter-Day Saint Religious Education

ERIC Educational Resources Information Center

Griffiths, Casey Paul; Esplin, Scott C.; Randall, E. Vance

2016-01-01

In recent years the educational programs of the Church of Jesus Christ of Latter-day Saints (LDS) have received praise for their role in the high rates of religiosity and denominational retention among their youth. This study offers a historical summary of the efforts of LDS to develop the most effective methods of engaging their youth in…

Saint Mary's College Teacher Science Institute: Converting Teachers to Using Guided Inquiry for Science Curricula

ERIC Educational Resources Information Center

McCarthy, Deborah; Bellina, Joseph J., Jr.

2003-01-01

In 1988 Saint Mary's College received a grant from Lilly Endowment, Inc. to create a program to improve the quality of science education in the local public and private schools. As part of applying that grant we created one-week summer work-shops for elementary and middle school teachers (K-8) based on guided inquiry methods of education. Each…

Severe paediatric conditions linked with EV-A71 and EV-D68, France, May to October 2016

PubMed Central

Antona, Denise; Kossorotoff, Manoëlle; Schuffenecker, Isabelle; Mirand, Audrey; Leruez-Ville, Marianne; Bassi, Clément; Aubart, Mélodie; Moulin, Florence; Lévy-Bruhl, Daniel; Henquell, Cécile; Lina, Bruno; Desguerre, Isabelle

2016-01-01

We report 59 cases of severe paediatric conditions linked with enterovirus (EV)-A71 and EV-D68 in France between May and October 2016. Fifty-two children had severe neurological symptoms. EV sequence-based typing for 42 cases revealed EV-A71 in 21 (18 subgenotype C1, detected for the first time in France) and EV-D68 in eight. Clinicians should be encouraged to obtain stool and respiratory specimens from patients presenting with severe neurological disorders for EV detection and characterisation. PMID:27918268

Prevalence of Attention Deficit Hyperactivity Disorder and Associated Features among Children in France

ERIC Educational Resources Information Center

Lecendreux, Michel; Konofal, Eric; Faraone, Stephen V.

2011-01-01

Background: Earlier studies point to the prevalence of attention deficit hyperactivity disorder (ADHD) to be similar around the world. There is, however, a wide variety in estimates. The prevalence of ADHD in youth has never been examined in France. Method: Starting with 18 million telephone numbers, 7,912 numbers are randomly selected. Among the…

Pharmacokinetics and pharmacodynamics of ch14.18/CHO in relapsed/refractory high-risk neuroblastoma patients treated by long-term infusion in combination with IL-2

PubMed Central

Siebert, Nikolai; Eger, Christin; Seidel, Diana; Jüttner, Madlen; Zumpe, Maxi; Wegner, Danilo; Kietz, Silke; Ehlert, Karoline; Veal, Gareth J.; Siegmund, Werner; Weiss, Michael; Loibner, Hans; Ladenstein, Ruth; Lode, Holger N.

2016-01-01

ABSTRACT Ch14.18 manufactured in Chinese hamster ovary (CHO) cells is currently being evaluated in clinical trials. Short-term infusion (STI) (8–20 h/day; 4–5 days) of 100 mg/m2 ch14.18/CHO (dinutiximab β) per cycle in combination with cytokines is standard treatment of neuroblastoma (NB) patients. As pain is a limiting factor, we investigated a novel delivery method by continuous long-term infusion (LTI) of 100 mg/m2 over 10 days. 53 NB patients were treated with 5–6 cycles of 6 × 106 IU/m2 subcutaneous interleukin-2 (d 1-5, 8-12), LTI of 100 mg/m2 ch14.18/CHO (d 8-18) and 160 mg/m2 oral 13-cis-retinoic acid (d 22-35). Human anti-chimeric antibody (HACA), antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity were determined. With LTI, we observed a maximum concentration of ch14.18/CHO (Cmax) of 12.56 ± 0.68 µg/ml and a terminal half-life time (t1/2 β) of 32.7 ± 16.2 d. The clearance values for LTI and STI of 0.54 ± 0.13 and 0.41 ± 0.29 L/d m2 and area under the serum concentration-time curve (AUC) values of 189.6 ± 41.4 and 284.8 ± 156.8 µg×d/ml, respectively, were not significantly different. Importantly, we detected ch14.18/CHO trough concentration of ≥ 1 µg/ml at time points preceding subsequent antibody infusions after cycle 1, allowing a persistent activation of antibody effector mechanisms over the entire treatment period of 6 months. HACA responses were observed in 10/53 (19%) patients, similar to STI (21%), indicating LTI had no effect on the immunogenicity of ch14.18/CHO. In conclusion, LTI of ch14.18/CHO induced effector mechanisms over the entire treatment period, and may therefore emerge as the preferred delivery method of anti-GD2 immunotherapy to NB patients. PMID:26785755

Long-term care financing: lessons from France.

PubMed

Doty, Pamela; Nadash, Pamela; Racco, Nathalie

2015-06-01

POLICY POINTS: France's model of third-party coverage for long-term services and supports (LTSS) combines a steeply income-adjusted universal public program for people 60 or older with voluntary supplemental private insurance. French and US policies differ: the former pay cash; premiums are lower; and take-up rates are higher, in part because employer sponsorship, with and without subsidization, is more common-but also because coverage targets higher levels of need and pays a smaller proportion of costs. Such inexpensive, bare-bones private coverage, especially if marketed as a supplement to a limited public benefit, would be more affordable to those Americans currently most at risk of "spending down" to Medicaid. An aging population leads to a growing demand for long-term services and supports (LTSS). In 2002, France introduced universal, income-adjusted, public long-term care coverage for adults 60 and older, whereas the United States funds means-tested benefits only. Both countries have private long-term care insurance (LTCI) markets: American policies create alternatives to out-of-pocket spending and protect purchasers from relying on Medicaid. Sales, however, have stagnated, and the market's viability is uncertain. In France, private LTCI supplements public coverage, and sales are growing, although its potential to alleviate the long-term care financing problem is unclear. We explore whether France's very different approach to structuring public and private financing for long-term care could inform the United States' long-term care financing reform efforts. We consulted insurance experts and conducted a detailed review of public reports, academic studies, and other documents to understand the public and private LTCI systems in France, their advantages and disadvantages, and the factors affecting their development. France provides universal public coverage for paid assistance with functional dependency for people 60 and older. Benefits are steeply income

Database of Vascular Plants of Canada (VASCAN): a community contributed taxonomic checklist of all vascular plants of Canada, Saint Pierre and Miquelon, and Greenland.

PubMed

Desmet, Peter; Brouillet, Luc

2013-01-01

The Database of Vascular Plants of Canada or VASCAN (http://data.canadensys.net/vascan) is a comprehensive and curated checklist of all vascular plants reported in Canada, Greenland (Denmark), and Saint Pierre and Miquelon (France). VASCAN was developed at the Université de Montréal Biodiversity Centre and is maintained by a group of editors and contributors. For every core taxon in the checklist (species, subspecies, or variety), VASCAN provides the accepted scientific name, the accepted French and English vernacular names, and their synonyms/alternatives in Canada, as well as the distribution status (native, introduced, ephemeral, excluded, extirpated, doubtful or absent) of the plant for each province or territory, and the habit (tree, shrub, herb and/or vine) of the plant in Canada. For reported hybrids (nothotaxa or hybrid formulas) VASCAN also provides the hybrid parents, except if the parents of the hybrid do not occur in Canada. All taxa are linked to a classification. VASCAN refers to a source for all name, classification and distribution information. All data have been released to the public domain under a CC0 waiver and are available through Canadensys and the Global Biodiversity Information Facility (GBIF). VASCAN is a service to the scientific community and the general public, including administrations, companies, and non-governmental organizations.

Geologic map of the Wrangell-Saint Elias National Park and Reserve, Alaska

USGS Publications Warehouse

Richter, Donald H.; Preller, Cindi C.; Labay, Keith A.; Shew, Nora B.

2006-01-01

Wrangell-Saint Elias National Park and Preserve, the largest national park within the U.S. National Park Service system, extends from the northern Pacific Ocean to beyond the eastern Alaska Range into interior Alaska. It features impressively spectacular scenery such as high and craggy mountains, active and ancient volcanoes, expansive ice fields, immense tidewater glaciers, and a myriad of alpine glaciers. The park also includes the famous Kennecott Mine, a world-class copper deposit that was mined from 1911 to 1938, and remnant ghost town, which is now a National Historic Landmark. Geologic investigations encompassing Wrangell-Saint Elias National Park and Preserve began in 1796, with Dmitriv Tarkhanov, a Russian mining engineer, who unsuccessfully ventured up the Copper River in search of rumored copper. Lieutenant H.T. Allen (1897) of the U.S. Army made a successful epic summer journey with a limited military crew up the Copper River in 1885, across the Alaska Range, and down the Tanana and Yukon Rivers. Allen?s crew was supported by a prospector named John Bremner and local Eyak and Ahtna native guides whose tribes controlled access into the Copper River basin. Allen witnessed the Ahtnas? many uses of the native copper. His stories about the copper prompted prospectors to return to this area in search of the rich copper ore in the years following his journey. The region boasts a rich mining and exploration history prior to becoming a park in 1980. Several U.S. Geological Survey geologists have conducted reconnaissance surveys in the area since Allen?s explorations. This map is the result of their work and is enhanced by more detailed investigations, which began in the late 1950s and are still continuing. For a better understanding of the processes that have shaped the geology of the park and a history of the geologic investigations in the area, we recommend U.S. Geological Survey Professional Paper 1616, ?A Geologic Guide to Wrangell-Saint Elias National Park

Predictive factors of cytomegalovirus seropositivity among pregnant women in Paris, France.

PubMed

N'Diaye, Dieynaba S; Yazdanpanah, Yazdan; Krivine, Anne; Andrieu, Thibaut; Rozenberg, Flore; Picone, Olivier; Tsatsaris, Vassilis; Goffinet, François; Launay, Odile

2014-01-01

Cytomegalovirus (CMV) is the most frequent cause of congenital infection. The objective of this study was to evaluate predictive factors for CMV seronegativity in a cohort of pregnant women in Paris, France. Pregnant women enrolled in a prospective cohort during the 2009 A/H1N1 pandemic were tested for CMV IgG antibodies. Variables collected were age, geographic origin, lifestyle, work characteristics, socioeconomic status, gravidity, parity and number of children at home. A multivariate logistic regression model was used to identify independent predictive factors for CMV seropositivity. Among the 826 women enrolled, 389 (47.1%) were primiparous, and 552 (67.1%) had Metropolitan France as a geographic origin. Out of these, 355 (i.e. 57.0%, 95% confidence interval (CI): [53.6%-60.4%]) were CMV seropositive: 43.7% (95% CI:[39.5%-47.9%]) in those whose geographic origin was Metropolitan France and 84.1% in those with other origins (95% CI:[79.2%-88.3%]). Determinants associated with CMV seropositivity in a multivariate logistic regression model were: (i) geographic origin (p<0.001(compared with Metropolitan France, geographic origins of Africa adjusted odds ratio (aOR) 21.2, 95% CI:[9.7-46.5], French overseas departments and territories and other origin, aOR 7.5, 95% CI:[3.9-14.6], and Europe or Asia, aOR 2.2, 95% CI: [1.3-3.7]); and (ii) gravidity (p = 0.019), (compared with gravidity = 1, if gravidity≥3, aOR = 1.5, 95% CI: [1.1-2.2]; if gravidity = 2, aOR = 1.0, 95% CI: [0.7-1.4]). Work characteristics and socioeconomic status were not independently associated with CMV seropositivity. In this cohort of pregnant women, a geographic origin of Metropolitan France and a low gravidity were predictive factors for CMV low seropositivity. Such women are therefore the likely target population for prevention of CMV infection during pregnancy in France.

Effects of Protection and Sediment Stress on Coral Reefs in Saint Lucia

PubMed Central

Bégin, Chantale; Schelten, Christiane K.; Nugues, Maggy M.; Hawkins, Julie; Roberts, Callum; Côté, Isabelle M.

2016-01-01

The extent to which Marine Protected Areas (MPAs) benefit corals is contentious. On one hand, MPAs could enhance coral growth and survival through increases in herbivory within their borders; on the other, they are unlikely to prevent disturbances, such as terrestrial runoff, that originate outside their boundaries. We examined the effect of spatial protection and terrestrial sediment on the benthic composition of coral reefs in Saint Lucia. In 2011 (10 to 16 years after MPAs were created), we resurveyed 21 reefs that had been surveyed in 2001 and analyzed current benthic assemblages as well as changes in benthic cover over that decade in relation to protection status, terrestrial sediment influence (measured as the proportion of terrigenous material in reef-associated sediment) and depth. The cover of all benthic biotic components has changed significantly over the decade, including a decline in coral and increase in macroalgae. Protection status was not a significant predictor of either current benthic composition or changes in composition, but current cover and change in cover of several components were related to terrigenous content of sediment deposited recently. Sites with a higher proportion of terrigenous sediment had lower current coral cover, higher macroalgal cover and greater coral declines. Our results suggest that terrestrial sediment is an important factor in the recent degradation of coral reefs in Saint Lucia and that the current MPA network should be complemented by measures to reduce runoff from land. PMID:26845451

Effects of Protection and Sediment Stress on Coral Reefs in Saint Lucia.

PubMed

Bégin, Chantale; Schelten, Christiane K; Nugues, Maggy M; Hawkins, Julie; Roberts, Callum; Côté, Isabelle M

2016-01-01

The extent to which Marine Protected Areas (MPAs) benefit corals is contentious. On one hand, MPAs could enhance coral growth and survival through increases in herbivory within their borders; on the other, they are unlikely to prevent disturbances, such as terrestrial runoff, that originate outside their boundaries. We examined the effect of spatial protection and terrestrial sediment on the benthic composition of coral reefs in Saint Lucia. In 2011 (10 to 16 years after MPAs were created), we resurveyed 21 reefs that had been surveyed in 2001 and analyzed current benthic assemblages as well as changes in benthic cover over that decade in relation to protection status, terrestrial sediment influence (measured as the proportion of terrigenous material in reef-associated sediment) and depth. The cover of all benthic biotic components has changed significantly over the decade, including a decline in coral and increase in macroalgae. Protection status was not a significant predictor of either current benthic composition or changes in composition, but current cover and change in cover of several components were related to terrigenous content of sediment deposited recently. Sites with a higher proportion of terrigenous sediment had lower current coral cover, higher macroalgal cover and greater coral declines. Our results suggest that terrestrial sediment is an important factor in the recent degradation of coral reefs in Saint Lucia and that the current MPA network should be complemented by measures to reduce runoff from land.

77 FR 42672 - Radio Broadcasting Services; Alberton, MT; Crystal Falls, MI; Saint Paul, AR; and Waitsburg, WA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-20

... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [MB Docket No. 12-115; DA 12-1084] Radio Broadcasting Services; Alberton, MT; Crystal Falls, MI; Saint Paul, AR; and Waitsburg, WA AGENCY: Federal Communications Commission. ACTION: Final rule. SUMMARY: The Audio Division, on its own motion, deletes four...

77 FR 31682 - In the Matter of Quintek Technologies, Inc., The Saint James Co., Urigen Pharmaceuticals, Inc...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-29

... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] In the Matter of Quintek Technologies, Inc., The Saint James Co., Urigen Pharmaceuticals, Inc., Valor Energy Corp., Wherify Wireless, Inc., and Win... Quintek Technologies, Inc. because it has not filed any periodic reports since the period ended September...

Severe paediatric conditions linked with EV-A71 and EV-D68, France, May to October 2016.

PubMed

Antona, Denise; Kossorotoff, Manoëlle; Schuffenecker, Isabelle; Mirand, Audrey; Leruez-Ville, Marianne; Bassi, Clément; Aubart, Mélodie; Moulin, Florence; Lévy-Bruhl, Daniel; Henquell, Cécile; Lina, Bruno; Desguerre, Isabelle

2016-11-17

We report 59 cases of severe paediatric conditions linked with enterovirus (EV)-A71 and EV-D68 in France between May and October 2016. Fifty-two children had severe neurological symptoms. EV sequence-based typing for 42 cases revealed EV-A71 in 21 (18 subgenotype C1, detected for the first time in France) and EV-D68 in eight. Clinicians should be encouraged to obtain stool and respiratory specimens from patients presenting with severe neurological disorders for EV detection and characterisation. This article is copyright of The Authors, 2016.

Saint-Gaudens National Historic Site: Home of a Gilded Age Icon. Teaching with Historic Places.

ERIC Educational Resources Information Center

Percoco, James A.

Augustus Saint-Gaudens (1848-1907) was a renowned 19th-century U.S. sculptor whose artistic training and talent ensured his place in Gilded Age society. In 1885, he was drawn to Cornish, New Hampshire, to find a place where he could model his latest commission, a statue of Abraham Lincoln. He and his wife established a summer home and studio in an…

Oxygen and strontium isotope tracing of human migration at the Bell Beaker site Le Tumulus des Sables, France.

NASA Astrophysics Data System (ADS)

Willmes, Malte; James, Hannah; Boel, Ceridwen; Courtaud, Patrice; Chancerel, Antoine; McMorrow, Linda; Armstrong, Richard; Kinsley, Les; Aubert, Maxime; Eggins, Stephen; Moffat, Ian; Grün, Rainer

2014-05-01

Oxygen (δ18O) and strontium (87Sr/86Sr) isotopes were used as tools to investigate human migration at the early Bell Beaker site (2500-2000 BC) Le Tumulus des Sables, Saint-Laurent-Médoc, south-west France. The O and Sr isotope ratios measured in tooth enamel record the average dietary isotope signature ingested by that individual during their childhood. When this data is compared to the isotope signature of the burial site it can be used to indicate if the individual migrated into this area during their lifetime. The O isotopic composition of meteoric water changes depending on climate, temperature and quantity of precipitation. O isotope ratios in skeletal and dental remains are related to body water, which in turn is influenced by diet, physiology and climate. Most of the water consumed by large mammals comes from drinking water, typically sourced locally. Sr isotope ratios on the other hand vary between different geologic regions, depending on their age and composition. Sr is released through weathering and transported into the soil, ground and surface water, where it becomes available for uptake by plants, enters the food cycle and eventually ends up in skeletal and dental tissue where it substitutes for calcium. We analysed the teeth of 18 adult and 8 juvenile disarticulated skeletons from Le Tumulus des Sables. O isotopes were analysed in-situ by Sensitive High Resolution Ion Micro Probe (SHRIMP).The Sr isotope analysis involved drilling a 0.2-0.5 mg sample of enamel from the tooth. The Sr was then chemically separated and analysed by Thermal Ionization Mass Spectrometry (TIMS). These results were then compared to the O isoscape of Europe and bioavailable Sr isotope data (fauna, plants, soils) from the IRHUM database. We found that most of the individuals at Le Tumulus des Sables show O and Sr isotope ratios corresponding to the local environmental signal and we interpret these as part of the local population. 3 adults however show slightly higher 87Sr/86

Characteristics of Patients with Alcohol Dependence Seeking Baclofen Treatment in France: A Two-Centre Comparative Cohort Study.

PubMed

Simioni, Nicolas; Preda, Cristian; Deken, Valérie; Bence, Camille; Cottencin, Olivier; Rolland, Benjamin

2016-11-01

To characterize the profile of patients seeking baclofen treatment for alcohol dependence in France. We compared retrospectively baclofen seekers and baclofen non-seekers within a cohort of consecutive outpatients with alcohol dependence who attended a first appointment for alcohol treatment at two French addiction centres between September 2012 and March 2014. We documented socio-demographic characteristics; comorbid psychiatric, addiction, alcohol dependence features; patients' initial drinking goal, and referral status; and treatment retention at 6 and 12 months. Of the 289 patients identified, 107 were baclofen seekers and 182 were baclofen non-seekers. The only parameters significantly associated with baclofen seekers in multivariate analyses were a greater baseline alcohol consumption (β = 15.4, 95% CI: 0.18-30.65, P = 0.05), a controlled-drinking initial goal (OR = 14.9, 95% CI: 7.7-29, P < 0.0001) and self-referral (OR = 6.6, 95% CI: 3.7-12, P < 0.0001), baclofen seekers being eight times more likely to be self-referred and treatment-naïve (OR = 8.8, 95% CI: 4.1-18.9, P < 0.0001). Baclofen seekers were more likely to be retained in treatment at 6 months (OR = 3.5, 95% CI: 1.8-6.7, P < 0.0001) and 12 months (OR = 1.9, 95% CI: 1.1-3.2, P = 0.019). In France, the perspective of controlled drinking offered by baclofen treatment may have attracted more self-referred patients, including those without previous alcohol treatment, to attend treatment, than the usual treatment options. These findings raise the question as to whether future public health strategies on alcohol should more prominently promote some aspects of alcohol treatment, such as patient's preference and treatment options, in order to reduce the treatment gap in alcohol dependence. © The Author 2016. Medical Council on Alcohol and Oxford University Press. All rights reserved.

Circulation of Pneumocystis dihydropteroate synthase mutants in France.

PubMed

Le Gal, Solène; Damiani, Céline; Perrot, Maëla; Rouillé, Amélie; Virmaux, Michèle; Quinio, Dorothée; Moalic, Elodie; Saliou, Philippe; Berthou, Christian; Le Meur, Yann; Totet, Anne; Nevez, Gilles

2012-10-01

Data on the prevalence of Pneumocystis jirovecii (P. jirovecii) dihydropteroate synthase (DHPS) mutants in France are still limited. In this study, mutant prevalence in the Brest region (western France) was determined. Archival pulmonary specimens from 85 patients infected with P. jirovecii and admitted to our institution (University Hospital, Brest) from October 2007 to February 2010 were retrospectively typed at the DHPS locus using a polymerase chain reaction-restriction fragment length polymorphism assay. Type identification was successful in 66 of 85 patients. Sixty-four patients were infected with a wild type, whereas mutants were found in 2 patients (2/66, 3%). Medical chart analysis revealed that these 2 patients usually lived in Paris. Another patient usually lived on the French Riviera, whereas 63 patients were from the city of Brest. Thus, the corrected prevalence of mutants in patients who effectively lived in our geographic area was 0% (0/63). Taking into account that i) Paris is characterized by a high prevalence of mutants from 18.5% to 40%, ii) infection diagnoses were performed in the 2 Parisians during their vacation <30 days, iii) infection incubation is assumed to last about 2 months, the results provide evidence of mutant circulation from Paris to Brest through infected vacationers. The study shows that the usual city of patient residence, rather than the city of infection diagnosis, is a predictor of mutants and that P. jirovecii infections involving mutants do not represent a public health issue in western France. Copyright © 2012 Elsevier Inc. All rights reserved.

Effect of Needle Size in Ultrasound-guided Core Needle Breast Biopsy: Comparison of 14-, 16-, and 18-Gauge Needles.

PubMed

Giuliani, Michela; Rinaldi, Pierluigi; Rella, Rossella; Fabrizi, Gina; Petta, Federica; Carlino, Giorgio; Di Leone, Alba; Mulè, Antonino; Bufi, Enida; Romani, Maurizio; Belli, Paolo; Bonomo, Lorenzo

2017-11-01

The aim of the present study was to assess the diagnostic accuracy of ultrasound-guided core needle biopsy (US-CNB) of breast lesions, comparing smaller needles (16- and 18-gauge) with the 14-gauge needle, and to analyze the lesion characteristics influencing US-CNB diagnostic performance. All the patients provided informed consent before the biopsy procedure. The data from breast lesions that had undergone US-CNB in our institution from January 2011 to January 2015 were retrospectively reviewed. The inclusion criterion was the surgical histopathologic examination findings of the entire lesion or radiologic follow-up data for ≥ 24 months. The exclusion criterion was the use of preoperative neoadjuvant therapy. The US-CNB results were compared with the surgical pathologic results or with the follow-up findings in the 3 needle size groups (14-, 16-, and 18-gauge). The needle size- and lesion characteristic-specific diagnostic accuracy parameters were evaluated. Statistical analysis was performed using a dedicated software program, and P ≤ .01 was considered significant. A total of 1118 US-CNB cases (1042 patients) were included. Of the 1118 cases, 630 (56.3%) were in the 14-gauge group, 136 (12.2%) in the 16-gauge, and 352 (31.5%) in the 18-gauge needle group. Surgery was performed on 800 lesions (71.6%). Of these, 619 were malignant, 77 were high risk, and 104 were benign. The remaining 318 lesions (28.4%) underwent follow-up imaging studies. All the lesions were stable and, therefore, were considered benign. No differences were observed in the diagnostic accuracy parameters among the 3 needle size groups (P > .01). The false-negative rate was greater for lesions < 10 mm (7.2%) (P < .01) but without statistically significant differences among the 3 gauges (P > .01). US-CNB performed with small needles (16 and 18 gauge) had the same diagnostic accuracy as that performed with 14-gauge needles, regardless of the lesion characteristics. Copyright © 2017

[Health status of populations living in French overseas territories in 2012, compared with metropolitan France: An analysis of the national health insurance database].

PubMed

Filipovic-Pierucci, A; Rigault, A; Fagot-Campagna, A; Tuppin, P

2016-06-01

This study uses healthcare consumption to compare the health status of beneficiaries of the French national health insurance general scheme between individuals living in French overseas territories (FOT) and those living in metropolitan France. Data were extracted from the French national health insurance database (Sniiram) for 2012, using algorithms, 56 groups of diseases and 27 groups of hospital activity were isolated. Standardized morbidity ratio for age and sex (SMR) were used to compare FOT to mainland France. Compared with mainland France, people living in the four FOT had high SMR for diabetes care (Guadeloupe 1.9; Martinique 1.7; Guyane 1.9; La Réunion 2.3), dialysis (2.7; 2.4; 3.8; 4.4), stroke (1.2; 1.1; 2.0; 1.5), and hospitalization for infectious diseases (1.9; 2.5; 2.4; 1.4) and obstetrics (1.4; 1.2; 1.9; 1.2). Care for inflammatory bowel disease or cancer were less frequent except for prostate in Martinique and Guadeloupe (2.3). People living in Martinique, Guadeloupe and la Reunion had more frequently care for psychotic disorders (2.0; 1.7; 1.2), dementia (1.1; 1.3; 11), epileptic seizures (1.4; 1.4; 16) and hospitalizations for burns (2.6; 1.7; 2.9). In la Reunion, people had more frequently coronary syndrome (1.3), cardiac heart failure (1.6), chronic respiratory diseases except cystic fibrosis (1.5), drug addiction (1.4) and hospitalizations for cardiovascular catheterization (1.4) and toxicology, poisoning, alcohol (1.7). Other differences were observed by gender: HIV infection, peripheral arterial disease, some chronic inflammatory disease (lupus) were more frequent in women living in Martinique or Guadeloupe, compared to women from mainland France and psychotic disorders for men. From la Reunion, men had more frequently liver and pancreatic diseases and hospitalisation for toxicology, poisoning, alcohol than men from mainland France. This study highlights the utility of administrative database to compare and follow population health status

Pedagogy of the Spirit: Comparing Evangelical and Latter-Day Saint Youth Self-Reported In-Class Spiritual Experiences

ERIC Educational Resources Information Center

Wong, Arch Chee Keen; Sweat, Anthony; Gardner, Ryan

2017-01-01

This study statistically analyzes data from 756 evangelical and Latter-day Saint youth regarding their perceived in-class spiritual experiences of twenty items related to Christian theology. The data indicates similar spiritual outcomes between the two groups, with no statistically significant differences between eleven of the twenty spiritual…

[Three centuries with the Fleet (to the 300th anniversary of the Saint-Petersburg naval hospital)].

PubMed

Buzov, E Ya; Kasatkin, V I; Makarenko, B G; Shilov, S A

2015-09-01

The authors analysed the history of the Saint-Petersburg naval hospital, founded in October, 1715 by Peter the Great, defined its role in the key historical events during organisation of medical, aid delivery to wounded and patients, discussed current tasks, concerning development of hospital art when forming modern image of the navy of the Russian Federation.

14 CFR 158.18 - Use of PFC revenue to pay for debt service for non-eligible projects.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS PASSENGER FACILITY CHARGES (PFC'S) General § 158.18 Use of PFC revenue to pay for debt service for non-eligible projects. (a) The FAA may authorize a public... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Use of PFC revenue to pay for debt service...

14 CFR 158.18 - Use of PFC revenue to pay for debt service for non-eligible projects.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS PASSENGER FACILITY CHARGES (PFC'S) General § 158.18 Use of PFC revenue to pay for debt service for non-eligible projects. (a) The FAA may authorize a public... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Use of PFC revenue to pay for debt service...

14 CFR 158.18 - Use of PFC revenue to pay for debt service for non-eligible projects.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS PASSENGER FACILITY CHARGES (PFC'S) General § 158.18 Use of PFC revenue to pay for debt service for non-eligible projects. (a) The FAA may authorize a public... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Use of PFC revenue to pay for debt service...

14 CFR 158.18 - Use of PFC revenue to pay for debt service for non-eligible projects.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS PASSENGER FACILITY CHARGES (PFC'S) General § 158.18 Use of PFC revenue to pay for debt service for non-eligible projects. (a) The FAA may authorize a public... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Use of PFC revenue to pay for debt service...

14 CFR 158.18 - Use of PFC revenue to pay for debt service for non-eligible projects.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS PASSENGER FACILITY CHARGES (PFC'S) General § 158.18 Use of PFC revenue to pay for debt service for non-eligible projects. (a) The FAA may authorize a public... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Use of PFC revenue to pay for debt service...

The first leg transplant for the treatment of a cancer by Saints Cosmas and Damian.

PubMed

Androutsos, G; Diamantis, A; Vladimiros, L

2008-01-01

The most renowned of all medically inclined saints must have been St. Cosmas and St. Damian. They became the special patrons of surgery, due to their miraculous operations. On one occasion, they amputated a cancerous leg and replaced it with another, taken from a Moor who had just died. This dramatic cure was meat and drink for artists, and has been portrayed many times.

[Rabies in France: an update].

PubMed

Jaussaud, R; Strady, C; Liénard, M; Strady, A

2000-08-01

In 1996, rabies was responsible for more than 35,000 deaths worldwide. Three cases of human rabies that had been contracted abroad were diagnosed in France during the same year. Cases notified in 1997 followed exposure outside the country. Fox, bat, and dog rabies are reviewed on the basis of the latest epidemiological data obtained in France. Two cases of fox rabies diagnosed in 1998 occurred at the border between France and Germany, thus preventing five French departments bordering Germany from being officially declared rabies-free in 1999. The campaigns for oral immunization of foxes that are led since 1986 are responsible for the decrease in rabies incidence. Though not well known, bat rabies is a reality in France, involving either European virus strains (five cases all over the country) or African virus strains that are carried along by imported tropical bats. Dogs rabies is also today an imported disease. The decrease in risk for rabies has resulted from the conjunction of multiple efforts: extensive programs aimed at oral vaccination of foxes in France and its neighboring countries, efficient epidemiological survey, sanitary controls at borders, ban on importing tropical bats. Furthermore, recommendations for preventive pre-exposure immunization have recently been changed, leading to modifications of the French licensing form.

Carbon transfer dynamics from bomb- 14C and δ 13C time series of a laminated stalagmite from SW France - modelling and comparison with other stalagmite records

NASA Astrophysics Data System (ADS)

Genty, Dominique; Massault, Marc

1999-05-01

Twenty-two AMS 14C measurements have been made on a modern stalagmite from SW France in order to reconstruct the 14C activity history of the calcite deposit. Annual growth laminae provides a chronology up to 1919 A.D. Results show that the stalagmite 14C activity time series is sensitive to modern atmosphere 14C activity changes such as those produced by the nuclear weapon tests. The comparison between the two 14C time series shows that the stalagmite time series is damped: its amplitude variation between pre-bomb and post-bomb values is 75% less and the time delay between the two time series peaks is 16 years ±3. A model is developed using atmosphere 14C and 13C data, fractionation processes and three soil organic matter components whose mean turnover rates are different. The linear correlation coefficient between modeled and measured activities is 0.99. These results, combined with two other stalagmite 14C time series already published and compared with local vegetation and climate, demonstrate that most of the carbon transfer dynamics are controlled in the soil by soil organic matter degradation rates. Where vegetation produces debris whose degradation is slow, the fraction of old carbon injected in the system increases, the observed 14C time series is much more damped and lag time longer than that observed under grassland sites. The same mixing model applied on the 13C shows a good agreement ( R2 = 0.78) between modeled and measured stalagmite δ 13C and demonstrates that the Suess Effect due to fossil fuel combustion in the atmosphere is recorded in the stalagmite but with a damped effect due to SOM degradation rate. The different sources of dead carbon in the seepage water are calculated and discussed.

Le role du phytoplancton de petite taille (<20 mum) dans les variations des proprietes optiques des eaux du Saint-Laurent

NASA Astrophysics Data System (ADS)

Mas, Sebastien

Les mesures satellitaires de couleur des oceans sont largement determinees par les proprietes optiques inherentes (IOPs) des eaux de surface. D'autre part, le phytoplancton de petite taille (<20 mum) est le plus souvent dominant dans les oceans, et peut donc etre une source importante de variation des IOPs dans les oceans. Dans ce contexte, le but principal de ce doctorat etait de definir l'impact du phytoplancton (<20 mum) sur les variations des proprietes optiques de l'Estuaire et du Golfe du Saint-Laurent (Canada). Afin d'atteindre cet objectif, il etait necessaire de determiner en milieu controle les facteurs de variabilite des proprietes optiques cellulaires et des IOPs du phytoplancton (<20 mum) des eaux du Saint-Laurent, et d'evaluer la contribution du phytoplancton (<20 mum) aux proprietes optiques totales des eaux du Saint-Laurent. Des experiences en laboratoire ont montre que les variations des proprietes optiques des cellules phytoplanctoniques soumises a un cycle jour-nuit, ainsi qu'a des changements concomitants d'intensite lumineuse, peuvent contribuer significativement a la variabilite des proprietes optiques observee en milieu naturel. D'autres experiences ont, quant a elles, mis en evidence que les variations des proprietes optiques des cellules phytoplanctoniques dues aux phases de croissance peuvent alterer les IOPs des oceans, particulierement pendant les periodes de floraison. De plus, la presence de bacteries et de particules detritiques peut egalement affecter la variabilite des IOPs totales, notamment la diffusion. Au printemps, dans l'Estuaire et le Golfe du Saint-Laurent, la contribution du phytoplancton <20 mum aux IOPs presentait des differences regionales evidentes pour les proprietes d'absorption et de diffusion. En plus de la variabilite spatiale, les proprietes optiques cellulaires presentaient des variations journalieres, et ce particulierement pour le picophytoplancton. Enfin, la plupart des differences observees dans les

First clinical case report of Cytauxzoon sp. infection in a domestic cat in France.

PubMed

Legroux, Jean-Pierre; Halos, Lénaïg; René-Martellet, Magalie; Servonnet, Marielle; Pingret, Jean-Luc; Bourdoiseau, Gilles; Baneth, Gad; Chabanne, Luc

2017-03-29

Feline cytauxzoonosis is an emerging infection caused by tick-transmitted apicomplexan parasites of the genus Cytauxzoon. The association of clinical disease with Cytauxzoon infection appears to be limited to C. felis infections in the Americas. Sporadic infections of wild and domestic felids with Cytauxzoon sp. were recently described in European countries but clinical reports of the infection are rare and incomplete. This case report brings new interesting information on cytauxzoonosis expression in Europe. A 9-years-old castrated European shorthair cat living in rural area of north-eastern France (Saint Sauveur, Bourgogne-Franche-Comté region), without any travel history was presented for consultation due to hyperthermia, anorexia, depression and prolonged fever that didn't respond to antibiotic therapy. The cat had outdoor access with a history of vagrancy and was adequately vaccinated (core vaccines and FeLV vaccine). During biological investigations, intraerythrocytic inclusions were observed on blood smear and were further investigated by PCR analysis and sequencing. Molecular analyses confirmed Cytauxzoon sp. infection. The cat was treated with a subcutaneous injection of imidocarb dipropionate (3.5 mg/kg). One week after treatment, the cat improved clinically, although parasitic inclusions within erythrocytes persisted, and only a mild lymphocytosis was found. Two weeks after treatment, the cat appeared in excellent health, appetite was normal and parasitemia was negative. However, one month after treatment the cat relapsed with hyperthermia, anorexia, and depression. Blood smears and PCR were once again positive. Subsequently, the cat received an additional dose of imidocarb dipropionate (3.5 mg/kg SC) and recovered rapidly without other clinical signs. Two weeks after the second imidocarb injection, the cat was hit by a car and died. This case provides the first clinical description of infection by Cytauxzoon sp. in a domestic cat in France. These

Bioelectromagnetics Research in France--An Assessment.

DTIC Science & Technology

1984-06-29

to level of the Defense Department. He was 5 years. The latter will help demon- replaced in normal rotation by a manager strate the breadth and scope...engineering. Unless support is found Ondes Electromagnetiques et Biologie immediately in industry or in other (Jouy en Josas, France, 1980), countries, France...Bioelectromagnetics de URSI, Ondes Electromagnetiques et Journal, not one French paper has been Biologie (Jouy en Josas, France, published in it. Whether any were

Generation of Novel Traj18-Deficient Mice Lacking Vα14 Natural Killer T Cells with an Undisturbed T Cell Receptor α-Chain Repertoire.

PubMed

Dashtsoodol, Nyambayar; Shigeura, Tomokuni; Ozawa, Ritsuko; Harada, Michishige; Kojo, Satoshi; Watanabe, Takashi; Koseki, Haruhiko; Nakayama, Manabu; Ohara, Osamu; Taniguchi, Masaru

2016-01-01

Invariant Vα14 natural killer T (NKT) cells, characterized by the expression of a single invariant T cell receptor (TCR) α chain encoded by rearranged Trav11 (Vα14)-Traj18 (Jα18) gene segments in mice, and TRAV10 (Vα24)-TRAJ18 (Jα18) in humans, mediate adjuvant effects to activate various effector cell types in both innate and adaptive immune systems that facilitates the potent antitumor effects. It was recently reported that the Jα18-deficient mouse described by our group in 1997 harbors perturbed TCRα repertoire, which raised concerns regarding the validity of some of the experimental conclusions that have been made using this mouse line. To resolve this concern, we generated a novel Traj18-deficient mouse line by specifically targeting the Traj18 gene segment using Cre-Lox approach. Here we showed the newly generated Traj18-deficient mouse has, apart from the absence of Traj18, an undisturbed TCRα chain repertoire by using next generation sequencing and by detecting normal generation of Vα19Jα33 expressing mucosal associated invariant T cells, whose development was abrogated in the originally described Jα18-KO mice. We also demonstrated here the definitive requirement for NKT cells in the protection against tumors and their potent adjuvant effects on antigen-specific CD8 T cells.

High-resolution infrared studies of the v 10, v 11, v 14, and v 18 levels of [1.1.1]propellane

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kirkpatrick, Robynne W.; Masiello, Tony; Martin, Matthew A.

2012-11-15

This paper is a continuation of earlier work for which the high resolution infrared spectrum of [1.1.1]propellane was measured and its k and l structure resolved for the first time. Here we present results from an analysis of more than 16,000 transitions involving three fundamental bands v 10 (E'-A1'), v 11 (E'-A1'), v 14 (A2''-A1') and two difference bands (v 10- v 18) (E'-E'') and (v 11-v 18) (E'-E"). Additional information about v18 was also obtained from the difference band (v 15+v 18)-v 18 (E'-E") and the binary combination band (v 15+v 18) (E'-A1'). Through the use of the groundmore » state constants reported in an earlier paper [1], rovibrational constants have been determined for all the vibrational states involved in these bands. The rovibrational parameters for the v 18(E'') state were obtained from combination-differences and showed no need to include interactions with other states. The v 10(E') state analysis was also straight-forward, with only a weak Coriolis interaction with the levels of the v 14(A2'') state. The latter levels are much more affected by a strong Coriolis interaction with the levels of the nearby v 11(E') state and also by a small but significant interaction with another state, presumably the v16(E'') state, that is not directly observed. Gaussian calculations (B3LYP/cc-pVTZ) computed at the anharmonic level aided the analyses by providing initial values for many of the parameters. These theoretical results generally compare favorably with the final parameter values deduced from the spectral analyses. Finally, evidence was obtained for several level crossings between the rotational levels of the v 11 and v 14 states and, using a weak coupling term corresponding to a Δk = ±5, Δl = ∓1 matrix element, it was possible to find transitions from the ground state that, combined with transitions to the same upper state, give a value of C 0 = 0.1936519(4) cm -1. This result, combined with the value of B 0 = 0.28755833(14) cm-1 reported

The Discernment Process of the Sisters of Saint Dominic regarding the Continued Sponsorship of Its Secondary Schools

ERIC Educational Resources Information Center

Tavis, Patricia

2010-01-01

The purpose of this dissertation was to examine the factors that a congregation of women religious, the Sisters of Saint Dominic of Caldwell, New Jersey, must consider in order to continue its sponsored relationship and the extent of this sponsored relationship with its secondary educational ministries for the future. This descriptive and…

Testing blood donors for Chagas disease in the Paris area, France: first results after 18 months of screening.

PubMed

El Ghouzzi, Marie-Hélène; Boiret, Elisabeth; Wind, Françoise; Brochard, Claudine; Fittere, Sébastien; Paris, Luc; Mazier, Dominique; Sansonetti, Nicole; Bierling, Philippe

2010-03-01

Chagas disease is endemic in Latin America (LA). Currently 10 million people are infected despite World Health Organization efforts aimed at preventing domestic transmission. However, with the migration of infected asymptomatic individuals to nonendemic countries, transmission of Chagas disease by transfusion may become a worldwide problem. The observation that the number of cases of Chagas disease has increased over the past 10 years in French Guiana, together with the results of a previous hospital-based study in the Paris area, confirms the transmission of Chagas disease from patients coming from LA. For these reasons, the French authorities stopped the collection of blood in French Guiana in 2005 and began screening blood donors in the French Caribbean islands and, in 2007, in continental France. Data on birth place, mother's birth place, and travel in LA were recorded for at-risk donors. These subjects were tested using two enzyme-linked immunosorbent assays (ELISAs). Of the 312,458 individuals who gave blood in the Paris area during an 18-month period, 30,837 were tested. Of these, 972 were born in LA, three of whom were positive for the two ELISAs and immunofluorescence tests. The prevalence of Trypanosoma cruzi-positive donors was 9.7 in 100,000 tested donors, but 0.31% among donors born in LA. Serology tests gave discrepant results in 1.02% of the samples. The efficiency of blood donor screening programs could be improved by screening only blood donors who were born in LA or who have traveled in LA for extended periods, using a single enzyme immunoassay.

Chateaubriant, France

NASA Image and Video Library

2010-03-08

This image, acquired 11-05-2007 by NASA Terra spacecraft, shows the city of Chateaubriant, France, surrounded by very old farmsteads. The surrounding countryside presents an interesting pattern of randomly oriented, small individual farmsteads.

33 CFR 165.760 - Security Zones; Tampa Bay, Port of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake...

Code of Federal Regulations, 2011 CFR

2011-07-01

... of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake, Old Port Tampa, Big Bend, Weedon..., Old Port Tampa, Big Bend, Weedon Island, and Crystal River, Florida. (a) Location. The following areas, denoted by coordinates fixed using the North American Datum of 1983 (World Geodetic System 1984), are...

33 CFR 165.760 - Security Zones; Tampa Bay, Port of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake...

Code of Federal Regulations, 2010 CFR

2010-07-01

... of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake, Old Port Tampa, Big Bend, Weedon..., Old Port Tampa, Big Bend, Weedon Island, and Crystal River, Florida. (a) Location. The following areas, denoted by coordinates fixed using the North American Datum of 1983 (World Geodetic System 1984), are...

33 CFR 165.760 - Security Zones; Tampa Bay, Port of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake...

Code of Federal Regulations, 2013 CFR

2013-07-01

... of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake, Old Port Tampa, Big Bend, Weedon..., Old Port Tampa, Big Bend, Weedon Island, and Crystal River, Florida. (a) Location. The following areas, denoted by coordinates fixed using the North American Datum of 1983 (World Geodetic System 1984), are...

33 CFR 165.760 - Security Zones; Tampa Bay, Port of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake...

Code of Federal Regulations, 2014 CFR

2014-07-01

... of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake, Old Port Tampa, Big Bend, Weedon..., Old Port Tampa, Big Bend, Weedon Island, and Crystal River, Florida. (a) Location. The following areas, denoted by coordinates fixed using the North American Datum of 1983 (World Geodetic System 1984), are...

33 CFR 165.760 - Security Zones; Tampa Bay, Port of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake...

Code of Federal Regulations, 2012 CFR

2012-07-01

... of Tampa, Port of Saint Petersburg, Port Manatee, Rattlesnake, Old Port Tampa, Big Bend, Weedon..., Old Port Tampa, Big Bend, Weedon Island, and Crystal River, Florida. (a) Location. The following areas, denoted by coordinates fixed using the North American Datum of 1983 (World Geodetic System 1984), are...

Analytical characterization of ch14.18: a mouse-human chimeric disialoganglioside-specific therapeutic antibody.

PubMed

Soman, Gopalan; Kallarakal, Abraham T; Michiel, Dennis; Yang, Xiaoyi; Saptharish, Nirmala; Jiang, Hengguang; Giardina, Steve; Gilly, John; Mitra, George

2012-01-01

Ch14.18 is a mouse-human chimeric monoclonal antibody to the disialoganglioside (GD2) glycolipid. In the clinic, this antibody has been shown to be effective in the treatment of children with high-risk neuroblastoma, either alone or in combination therapy. Extensive product characterization is a prerequisite to addressing the potential issues of product variability associated with process changes and manufacturing scale-up. Charge heterogeneity, glycosylation profile, molecular state and aggregation, interaction (affinity) with Fcγ receptors and functional or biological activities are a few of the critical characterization assays for assessing product comparability for this antibody. In this article, we describe the in-house development and qualification of imaged capillary isoelectric focusing to assess charge heterogeneity, analytical size exclusion chromatography with online static and dynamic light scattering (DLS), batch mode DLS for aggregate detection, biosensor (surface plasmon resonance)-based Fcγ receptor antibody interaction kinetics, N-glycoprofiling with PNGase F digestion, 2-aminobenzoic acid labeling and high performance liquid chromatography and N-glycan analysis using capillary electrophoresis. In addition, we studied selected biological activity assays, such as complement-dependent cytotoxicity. The consistency and reproducibility of the assays are established by comparing the intra-day and inter-day assay results. Applications of the methodologies to address stability or changes in product characteristics are also reported. The study results reveal that the ch14.18 clinical product formulated in phosphate-buffered saline at a concentration of 5 mg/ml and stored at 2-8°C is stable for more than five years.

Structure and Tectonics of the Saint Elias Orogen

NASA Astrophysics Data System (ADS)

Bruhn, R. L.; Pavlis, T. L.; Plafker, G.; Serpa, L.; Picornell, C.

2001-12-01

The Saint Elias orogen of western Canada and southern Alaska is a complex mountain belt formed by transform faulting and subduction between the Pacific and North American plates, and collision of the Yakutat terrane. The orogen is segmented into three regions of different structural style caused by lateral variations in transpression and processes of terrane accretion. Deformation is strain and displacement partitioned throughout the orogen; transcurrent motion is focused along discrete strike-slip faults, and shortening is distributed among reverse faults and folds with sub-horizontal axes. Plunging folds accommodate horizontal shortening and extension in the western part of the orogen. Segment boundaries extend across the Yakutat terrane where they coincide with the courses of huge piedmont glaciers that flow from the topographic backbone of the range onto the coastal plain. The eastern segment is marked by strike-slip faulting along the Fairweather transform fault and by a narrow belt of reverse faulting where the transpression ratio is 0.4:1 shortening to dextral shear. The transpression ratio is 1.7:1 in the central part of the orogen where a broad thin-skinned fold and thrust belt deforms the Yakutat terrane south of the Chugach-Saint Elias (CSE) suture. Dextral shearing is accommodated by strike-slip faulting beneath the Seward and Bagley glaciers in the hanging wall of the CSE suture, and partly by reverse faulting along a structural belt that cuts across the Yakutat terrane along the western edge of the Malaspina Glacier and links to the Pamplona fold and thrust belt offshore. Deformation along this segment boundary is probably also driven by vertical axis bending of the Yakutat microplate during collision. Subduction & accretion in the western segment of the orogen causes re-folding of previously formed structures when they are emplaced into the upper plate of the Alaska-Aleutian mega-thrust. Second phase folds plunge at moderate to steep angles and

Fate and forms of Cu in a reservoir ecosystem following copper sulfate treatment (Saint Germain les Belles, France)

NASA Astrophysics Data System (ADS)

van Hullebusch, E.; Chatenet, P.; Deluchat, V.; Chazal, P. M.; Froissard, D.; Lens, P. N. L.; Baudu, M.

2003-05-01

Copper sulfate (CuSO4) addition to freshwater for phytoplankton control has been practiced for decades, and remains the most effective algicidal treatment for numerous managed water bodies. A reservoir in the centre of France was the site for an investigation of copper distribution in aquatic systems after a copper sulfate treatment Results of copper monitoring showed a rapid conversion of dissolved Cu to particulate forms, with significant accumulation in the sediments/83% of total copper added). Total sediment Cu content increasedfrom approximately 37.7 to 45.4 μg.g^{-1} dry weight after the first treatment. Sequential extraction suggested that a significanl portion of the sediment-borne Cu was associated with the organic fraction which may release Cu to the water column, although significant release would occur only under extreme changes in water chemistry. Based upon measured Cu concentrations, flows at the down-stream water, and known mass applied during treatment, mass balance calculations indicated that approximately 17% of the Cu was exported from the reservoir over a 70 day period following a 196 μg.L^{-l} Cu^{2+} (as CuSO4, 5 H2O) treatment. The largest amount of copper was probably adsorbed on downstream sediment or lost in running water, Copper bioaccumulation by a moss, Fontinalis antipyretica, in the down-stream water showed that it was possible to distinguish between a treated and an untreated area. The impact of copper treatment in the down-stream reservoir could be followed using mosses. The bioaccumulation data further showed that there is a distance effect which could be exploited to determine potential copper impact on receiving water bodies. Thirty days after copper sulfate addition, Fontinalis still indicated copper exposure.

77 FR 76156 - Self-Regulatory Organizations; ICE Clear Credit LLC; Notice of Filing of Proposed Rule Change To...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-26

... public limited company; COMPAGNIE DE SAINT-GOBAIN; Deutsche Telekom AG; FRANCE TELECOM; GAS NATURAL SDG....; Koninklijke KPN N.V.; NATIONAL GRID PLC; Portugal Telecom International Finance B.V.; RWE Aktiengesellschaft; TELECOM ITALIA SPA; TELEFONICA, S.A.; Telekom Austria Aktiengesellschaft; TELENOR ASA; TeliaSonera...

Women in physics in France

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pierron-Bohnes, Véronique

We present six associations and entities working in France on issues of women in physics: the Women and Physics Commission, French Physical Society; Women in Nuclear (WiN) France; Women and Science Association; Mission for the Place of Women at CNRS; Parity, Diversity, and Women Network, CEA; and the Network of University Equality-Diversity Representatives.

Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli

PubMed Central

2012-01-01

Background With the increasing stress from oil price and environmental pollution, aroused attention has been paid to the microbial production of chemicals from renewable sources. The C12/14 and C16/18 alcohols are important feedstocks for the production of surfactants and detergents, which are widely used in the most respected consumer detergents, cleaning products and personal care products worldwide. Though bioproduction of fatty alcohols has been carried out in engineered E. coli, several key problems have not been solved in earlier studies, such as the quite low production of C16/18 alcohol, the lack of optimization of the fatty alcohol biosynthesis pathway, and the uncharacterized performance of the engineered strains in scaled-up system. Results We improved the fatty alcohol production by systematically optimizing the fatty alcohol biosynthesis pathway, mainly targeting three key steps from fatty acyl-acyl carrier proteins (ACPs) to fatty alcohols, which are sequentially catalyzed by thioesterase, acyl-coenzyme A (CoA) synthase and fatty acyl-CoA reductase. By coexpression of thioesterase gene BTE, acyl-CoA synthase gene fadD and fatty acyl-CoA reductase gene acr1, 210.1 mg/L C12/14 alcohol was obtained. A further optimization of expression level of BTE, fadD and acr1 increased the C12/14 alcohol production to 449.2 mg/L, accounting for 75.0% of the total fatty alcohol production (598.6 mg/L). In addition, by coexpression of thioesterase gene ‘tesA, acyl-CoA synthase gene fadD and fatty acyl-CoA reductase gene FAR, 101.5 mg/L C16/18 alcohol was obtained, with C16/18 alcohol accounting for 89.2% of the total fatty alcohol production. Conclusions To our knowledge, this is the first report on selective production of C12/14 and C16/18 alcohols by microbial fermentation. This work achieved high-specificity production of both C12/14 and C16/18 alcohols. The encouraging 598.6 mg/L of fatty alcohols represents the highest titer reported so far. In

France acts on electronic cigarettes.

PubMed

Cahn, Zachary

2013-11-01

France is deciding how to regulate electronic cigarettes. I first consider the French approach and how it contrasts with other attempts at electronic cigarette regulation globally. Next, I critique the individual elements of the French proposal. The overall approach taken by France is a positive development, but banning indoor use appears unnecessary and banning advertising may be counterproductive.

77 FR 15600 - Special Local Regulation; Emerald Coast Super Boat Grand Prix; Saint Andrew Bay; Panama City, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-16

...-AA08 Special Local Regulation; Emerald Coast Super Boat Grand Prix; Saint Andrew Bay; Panama City, FL... navigable waters during the Emerald Coast Super Boat Grand Prix high speed boat races. Entry into... Marine Event Permit on January 31, 2011 from Super Boat International, Inc. to conduct a high speed boat...

What makes a Catholic hospital "Catholic" in an age of religious-secular collaboration? The case of the Saint Marys hospital and the Mayo Clinic.

PubMed

Swetz, Keith M; Crowley, Mary E; Maines, T Dean

2013-06-01

Mayo Clinic is recognized as a worldwide leader in innovative, high-quality health care. However, the Catholic mission and ideals from which this organization was formed are not widely recognized or known. From partnership with the Sisters of St. Francis in 1883, through restructuring of the Sponsorship Agreement in 1986 and current advancements, this Catholic mission remains vital today at Saint Marys Hospital. This manuscript explores the evolution and growth of sponsorship at Mayo Clinic, defined as "a collaboration between the Sisters of St. Francis and Mayo Clinic to preserve and promote key values that the founding Franciscan sisters and Mayo physicians embrace as basic to their mission, and to assure the Catholic identity of Saint Marys Hospital." Historical context will be used to frame the evolution and preservation of Catholic identity at Saint Marys Hospital; and the shift from a "sponsorship-by-governance" to a "sponsorship-by-influence" model will be highlighted. Lastly, using the externally-developed Catholic Identity Matrix (developed by Ascension Health and the University of St. Thomas, Minnesota), specific examples of Catholic identity will be explored in this joint venture of Catholic health care institution and a secular, nonprofit corporation (Mayo Clinic).

78 FR 25365 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... applies. FAA's Determination These helicopters have been approved by the aviation authority of France and...

Increased risk of narcolepsy in children and adults after pandemic H1N1 vaccination in France.

PubMed

Dauvilliers, Yves; Arnulf, Isabelle; Lecendreux, Michel; Monaca Charley, Christelle; Franco, Patricia; Drouot, Xavier; d'Ortho, Marie-Pia; Launois, Sandrine; Lignot, Séverine; Bourgin, Patrice; Nogues, Béatrice; Rey, Marc; Bayard, Sophie; Scholz, Sabine; Lavault, Sophie; Tubert-Bitter, Pascale; Saussier, Cristel; Pariente, Antoine

2013-08-01

An increased incidence of narcolepsy in children was detected in Scandinavian countries where pandemic H1N1 influenza ASO3-adjuvanted vaccine was used. A campaign of vaccination against pandemic H1N1 influenza was implemented in France using both ASO3-adjuvanted and non-adjuvanted vaccines. As part of a study considering all-type narcolepsy, we investigated the association between H1N1 vaccination and narcolepsy with cataplexy in children and adults compared with matched controls; and compared the phenotype of narcolepsy with cataplexy according to exposure to the H1N1 vaccination. Patients with narcolepsy-cataplexy were included from 14 expert centres in France. Date of diagnosis constituted the index date. Validation of cases was performed by independent experts using the Brighton collaboration criteria. Up to four controls were individually matched to cases according to age, gender and geographic location. A structured telephone interview was performed to collect information on medical history, past infections and vaccinations. Eighty-five cases with narcolepsy-cataplexy were included; 23 being further excluded regarding eligibility criteria. Of the 62 eligible cases, 59 (64% males, 57.6% children) could be matched with 135 control subjects. H1N1 vaccination was associated with narcolepsy-cataplexy with an odds ratio of 6.5 (2.1-19.9) in subjects aged<18 years, and 4.7 (1.6-13.9) in those aged 18 and over. Sensitivity analyses considering date of referral for diagnosis or the date of onset of symptoms as the index date gave similar results, as did analyses focusing only on exposure to ASO3-adjuvanted vaccine. Slight differences were found when comparing cases with narcolepsy-cataplexy exposed to H1N1 vaccination (n=32; mostly AS03-adjuvanted vaccine, n=28) to non-exposed cases (n=30), including shorter delay of diagnosis and a higher number of sleep onset rapid eye movement periods for exposed cases. No difference was found regarding history of infections. In

[Rochus, patron saint of physicians and hospitals--a teledermatologic quiz].

PubMed

Aberer, Werner

2006-07-01

The painting "St. Rochus with an angel" by Quinten Massys in the Alte Pinakothek in Munich was utilized for a teledermatological quiz. First, only a detail of the plague bubo on the thigh was sent electronically to all physicians in our department. The answers were correct descriptions, but the interpretations quite heterogeneous. In a second set, the full painting together with the hint- Pinakothek - was given. Now the number of descriptively correct diagnoses was high; one resident knew the name of the featured individual and his diagnosis. This example demonstrates one problem with teledermatology - when viewing a clinical picture, relevant additional information is frequently essential in order to make a correct diagnosis. In addition, this presentation of saint physicians and hospitals, the holy Rochus, better known to those who are under his protection.

Saint-Venant end effects for materials with negative Poisson's ratios

NASA Technical Reports Server (NTRS)

Lakes, R. S.

1992-01-01

Results are presented from an analysis of Saint-Venant end effects for materials with negative Poisson's ratio. Examples are presented showing that slow decay of end stress occurs in circular cylinders of negative Poisson's ratio, whereas a sandwich panel containing rigid face sheets and a compliant core exhibits no anomalous effects for negative Poisson's ratio (but exhibits slow stress decay for core Poisson's ratios approaching 0.5). In sand panels with stiff but not perfectly rigid face sheets, a negative Poisson's ratio results in end stress decay, which is faster than it would be otherwise. It is suggested that the slow decay previously predicted for sandwich strips in plane deformation as a result of the geometry can be mitigated by the use of a negative Poisson's ratio material for the core.

10 μm High-resolution spectrum of trans -acrolein: Rotational analysis of the ν 11 , ν 16 , ν 14 and ν 16 + ν 18 - ν 18 bands

NASA Astrophysics Data System (ADS)

Xu, Li-Hong; Jiang, Xingjie; Shi, Hongyu; Lees, R. M.; McKellar, A. R. W.; Tokaryk, D. W.; Appadoo, D. R. T.

2011-07-01

High-resolution Fourier transform spectra of trans-acrolein, H 2C dbnd C(H) sbnd C(H) dbnd O, have been recorded in the 10 μm region at both room and cooled temperatures on the modified Bomem DA3.002 at the National Research Council of Canada and the Bruker IFS 125HR spectrometer at the far infrared beam line of the Canadian Light Source in Saskatoon. Vibrational fundamentals analyzed so far include the ν11, ν16 and ν14 bands centered at 911.3, 958.7 and 992.7 cm -1 corresponding respectively to the A' in-plane dbnd CH 2-rocking mode, the A″ out-of-plane dbnd CH 2-wagging mode, and the A″ wagging mode highly mixed between the ⩾C sbnd H vinyl and ⩾C sbnd H formyl groups [Vibrational mode descriptions are based on Y.N. Panchenko, P. Pulay, F. Török, J. Mol. Spectrosc. 34 (1976) 283-289.] As well, the ν16 + ν18 - ν18 hot band centred at 957.6 cm -1 has been analyzed, where ν18 is the low-frequency (157.9 cm -1) A″ ⩾C sbnd C ⪕ torsional mode. The ν11 band is a/ b type while the ν16, ν14 and ν16 + ν18 - ν18 bands are c-type. The assigned transitions of each band have been fitted to a Watson asymmetric rotor Hamiltonian, with ground state parameters fixed to values obtained from rotational analyses in the literature. As well, a combined 3-state fit for ν11, ν16 and ν14 was carried out including Coriolis and Z1 constants which account for J and Δ K interactions. Transition dipole moments have been calculated for each of the fundamentals using the ab initio B3LYP method and 6-311++G ∗∗ basis set. For the A' vibrational modes, we have also evaluated transition dipole a- and b-components in the principal axis system from vibrational displacements and dipole moment derivatives. Our ab initio results predict that the ν11 in-plane dbnd CH 2 rocking mode has an a-type transition strength about three times greater than the b-type, which is consistent with our observations. Our ab initio force field analysis gives vibrational mode

A leukemic double-hit follicular lymphoma associated with a complex variant translocation, t(8;14;18)(q24;q32;q21), involving BCL2, MYC, and IGH.

PubMed

Minakata, Daisuke; Sato, Kazuya; Ikeda, Takashi; Toda, Yumiko; Ito, Shoko; Mashima, Kiyomi; Umino, Kento; Nakano, Hirofumi; Yamasaki, Ryoko; Morita, Kaoru; Kawasaki, Yasufumi; Sugimoto, Miyuki; Yamamoto, Chihiro; Ashizawa, Masahiro; Hatano, Kaoru; Oh, Iekuni; Fujiwara, Shin-Ichiro; Ohmine, Ken; Kawata, Hirotoshi; Muroi, Kazuo; Miura, Ikuo; Kanda, Yoshinobu

2018-01-01

Double-hit lymphoma (DHL) is defined as lymphoma with concurrent BCL2 and MYC translocations. While the most common histological subtype of DHL is diffuse large B-cell lymphoma, the present patient had leukemic follicular lymphoma (FL). A 52-year-old man was admitted to our hospital due to general fatigue and cervical and inguinal lymph node swelling. The patient was leukemic and the pathological diagnosis of the inguinal lymph node was FL grade 1. Chromosomal analysis revealed a complex karyotype including a rare three-way translocation t(8;14;18)(q24;q32;q21) involving the BCL2, MYC, and IGH genes. Based on a combination of fluorescence in situ hybridization (FISH), using BCL2, MYC and IGH, and spectral karyotyping (SKY), the karyotype was interpreted as being the result of a multistep mechanism in which the precursor B-cell gained t(14;18) in the bone marrow and acquired a translocation between der(14)t(14;18) and chromosome 8 in the germinal center, resulting in t(8;14;18). The pathological diagnosis was consistently FL, not only at presentation but even after a second relapse. The patient responded well to standard chemotherapies but relapsed after a short remission. This patient is a unique case of leukemic DH-FL with t(8;14;18) that remained in FL even at a second relapse. Copyright © 2017 Elsevier Inc. All rights reserved.

77 FR 54796 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-06

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT... France Model AS350 helicopters. This AD requires installing protection sleeves over certain forward... helicopters have been approved by the aviation authority of France and are approved for operation in the...

78 FR 18230 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-26

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... approved by the aviation authority of France and is approved for operation in the United States. Pursuant...

78 FR 65871 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-04

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral...

77 FR 44118 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-27

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA... airworthiness directive (AD) for Eurocopter France (Eurocopter) Model EC155B1 helicopters with a certain... Determination These helicopters have been approved by the aviation authority of France and are approved for...

78 FR 25380 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... Determination These helicopters have been approved by the aviation authority of France and are approved for...

77 FR 70360 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-26

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for all Eurocopter France... France and are approved for operation in the United States. Pursuant to our bilateral agreement with...

77 FR 5994 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-07

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA... airworthiness directive (AD) for all Eurocopter France EC130B4 helicopters that have not had Eurocopter... actions. FAA's Determination These helicopters have been approved by the aviation authority of France and...

78 FR 59306 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-26

...-0826; Directorate Identifier 2011-SW-046-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... helicopters have been approved by the aviation authority of France and [[Page 59307

78 FR 857 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-07

... Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France (Eurocopter... been approved by the aviation authority of France and are approved for operation in the United States...

Wine and tobacco: risk factors for gastric cancer in France.

PubMed

Hoey, J; Montvernay, C; Lambert, R

1981-06-01

Cross-sectional studies in France have shown strong regional correlations between death rates from alcohol related diseases and death rates from gastric cancer. The present study involved 40 cases of newly diagnosed adenocarcinoma of the stomach and 168 control subjects with one of four other gastrointestinal diagnoses selected from the same hospital service during the same time period, 1978-1980. On the basis of a standard nutritional interview alcohol and particularly red wine were seen to be significant risk factors for this cancer (relative risks of 6.9 with 95% confidence limits (CL) of 3.3-14.3 for alcohol and 6.3 with CL 3.1-12.7 for wine). Smoking of one or more cigarettes per day was associated with a relative risk for gastric cancer of 4.8 with CL of 1.6-14.8. The presence of both risk factors was associated with a relative risk of 9.3 with 95% CL of 4.6-19.0. Possible confounding by age, smoking, and eating lettuce (a reported protective factor for gastric cancer in other studies) did not explain these results. The relative risks were consistently found and remained significant when each diagnostic group of control subjects was analyzed separately. These results suggest that alcohol, and particularly red wine, may be important risk factors for adenocarcinoma of the stomach in France. In addition, cigarette smoking, a risk factor in itself, when coupled with alcohol appears markedly to increase the risk.

The Human Side of 18th-Century French History: Unique Readings for Secondary Students

ERIC Educational Resources Information Center

Roselle, Daniel, Ed.

1976-01-01

Nine short stories and excerpts are presented relating to 18th-Century French History. The purpose of the readings are to: 1) increase student sensitivity to conditions in 18th-Century France; 2) add to their appreciation of the variety of human experiences; and 3) strengthen student insight into the nature of human beings. (Author/JR)

78 FR 1739 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-09

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for all Eurocopter France... Directorate General for Civil Aviation (DGAC France) AD F-2008-04, dated June 4, 2008, for the Eurocopter...

78 FR 9634 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

...-0119; Directorate Identifier 2011-SW-034-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... helicopter. FAA's Determination These helicopters have been approved by the aviation authority of France and...

78 FR 59298 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-26

...-1158; Directorate Identifier 2010-SW-018-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to revise airworthiness directive (AD) 2011-22-05 for Eurocopter France (Eurocopter...'s Determination These helicopters have been approved by the aviation authority of France and are...

77 FR 5991 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-07

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA... airworthiness directive (AD) for the Eurocopter France (ECF) Model AS332L2 helicopter and superseding an AD for... of France and are approved for operation in the United States. Pursuant to our bilateral agreement...

The Impact of Crunchy Wednesdays on Happy Meal Fruit Orders: Analysis of Sales Data in France, 2009-2013.

PubMed

Drewnowski, Adam; Michels, Serge; Leroy, Diane

2017-03-01

Beginning in September, 2010, all McDonald's restaurants in France offered free fruit with every Happy Meal sold on the first Wednesday of the month. Sales data were used to determine the impact of free fruit promotion on the proportion of regular Happy Meal fruit desserts sold. Trend analyses examined the proportion of fruit desserts for 2009-2013. Analyses also compared fruit orders on Crunchy Wednesdays with other weekdays. Happy Meal fruit desserts rose from 14.5% in 2010 to 18.0% in 2011 and to 19.4% in 2013 (P < .001). More Happy Meal fruit desserts were ordered on Crunchy Wednesdays compared with other weekdays (P < .001). Orders of cherry tomato sides and water as a beverage on Crunchy Wednesdays were unaffected. Based on sales transactions data across multiple years, this study provides evidence of the long-term effectiveness of menu promotions aimed at increasing children's consumption of vegetables and fruit. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

77 FR 18967 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-29

...-0339; Directorate Identifier 2011-SW-051-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all Eurocopter France (Eurocopter... Airworthiness Directive (AD): Eurocopter France: Docket No. FAA-2012-0339; Directorate Identifier 2011-SW-051-AD...

78 FR 44043 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-23

...-0635; Directorate Identifier 2012-SW-081-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... France and are approved for operation in the United States. Pursuant to our bilateral agreement with...

78 FR 23462 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-19

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA... airworthiness directive (AD) for Eurocopter France (Eurocopter) Model AS332C, AS332L, and AS332L1 helicopters... helicopters have been approved by the aviation authority of France and are approved for operation in the...

78 FR 16200 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-14

...-0240; Directorate Identifier 2011-SW-060-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Eurocopter France (Eurocopter... helicopters have been approved by the aviation authority of France and are approved for operation in the...

77 FR 44509 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

...-0795; Directorate Identifier 2008-SW-53-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... by the aviation authority of the France and are approved for operation in the United States. Pursuant...

78 FR 33764 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-05

...-0479; Directorate Identifier 2011-SW-070-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement...

77 FR 36216 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-18

...-0631; Directorate Identifier 2011-SW-021-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

77 FR 43734 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-26

...-0774; Directorate Identifier 2010-SW-057-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... Determination This helicopter model is manufactured in France and is type certificated for operation in the...

78 FR 37154 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-20

...-0523; Directorate Identifier 2012-SW-091-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France (Eurocopter) Model... Determination These helicopters have been approved by the aviation authority of France and are approved for...

78 FR 51115 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-20

...-0737; Directorate Identifier 2012-SW-111-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Eurocopter France (Eurocopter... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

[An image of Saint Ottilia with reading stones].

PubMed

Daxecker, F; Broucek, A

1995-01-01

Reading stones to facilitate reading in cases of presbyopia are mentioned in the literature, for example in the works of the Middle High German poet Albrecht and of Konrad of Würzburg. Most representations of the abbess, Saint Ottilia, show her holding a book with a pair of eyes in her hands. A gothic altarpiece (1485-1490), kept in the museum of the Premonstratensian Canons of Wilten in Innsbruck, Tyrol, shows a triune representation of St. Anne, the mother of the Virgin, with Mary and Jesus and St. Ursula with her companions. St. Ottilia is depicted on the edge of the painting. Two lenses, one on either side of the open book in her hand, magnify the letters underneath. As the two lenses are not held together by bows or similar devices, they are probably a rare representation of reading stones. The alter showing scenes of the life of St. Mary and St. Ursula was done by Ludwig Konraiter. A panel on the same alter, depicting the death of the Virgin, shows an apostle with rivet spectacles.

77 FR 20319 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-04

...-0354; Directorate Identifier 2010-SW-104-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all Eurocopter France (EC) Model SA... France: Docket No. FAA-2012-0354; Directorate Identifier 2010-SW-104-AD. (a) Applicability This AD...

77 FR 50582 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-22

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for Eurocopter France... 39 to include an AD that would apply to Eurocopter France Model EC155B and EC155B1 helicopters with a...

77 FR 18965 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-29

...-0338; Directorate Identifier 2009-SW-51-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France Model SA341G.... Discussion The Direction Generale de l'Aviation Civile (DGAC), which is the aviation authority for France...

77 FR 14310 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-09

...-0222; Directorate Identifier 2011-SW-007-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for certain Eurocopter France Model AS350... Determination These products have been approved by the aviation authority of France and are approved for...

Fullerene-like boron clusters stabilized by an endohedrally doped iron atom: B(n)Fe with n = 14, 16, 18 and 20.

PubMed

Tam, Nguyen Minh; Pham, Hung Tan; Duong, Long Van; Pham-Ho, My Phuong; Nguyen, Minh Tho

2015-02-07

Stabilized fullerene and tubular forms can be produced in boron clusters Bn in small sizes from n∼ 14 to 20 upon doping by transition metal atoms. B14Fe and B16Fe are stable tubes whereas B18Fe and B20Fe are stable fullerenes. Their formation and stability suggest the use of dopants to induce different growth paths leading to larger cages, fullerenes and tubes of boron.

Extended Maintenance Downtime 12/14 - 12/18

Atmospheric Science Data Center

2015-12-07

... am - 12/18 @ 5 pm EST Event Impact:  File System Maintenance will be performed on a number of the large file systems ... and Customization Tool -  AMAPS, CALIPSO, CERES, MOPITT, TES and TAD Search and Subset Tools   While some sites and tools may ...

Targeting Rapamycin to Podocytes Using a Vascular Cell Adhesion Molecule-1 (VCAM-1)-Harnessed SAINT-Based Lipid Carrier System

PubMed Central

Visweswaran, Ganesh Ram R.; Gholizadeh, Shima; Ruiters, Marcel H. J.; Molema, Grietje; Kok, Robbert J.; Kamps, Jan. A. A. M.

2015-01-01

Together with mesangial cells, glomerular endothelial cells and the basement membrane, podocytes constitute the glomerular filtration barrier (GFB) of the kidney. Podocytes play a pivotal role in the progression of various kidney-related diseases such as glomerular sclerosis and glomerulonephritis that finally lead to chronic end-stage renal disease. During podocytopathies, the slit-diaphragm connecting the adjacent podocytes are detached leading to severe loss of proteins in the urine. The pathophysiology of podocytopathies makes podocytes a potential and challenging target for nanomedicine development, though there is a lack of known molecular targets for cell selective drug delivery. To identify VCAM-1 as a cell-surface receptor that is suitable for binding and internalization of nanomedicine carrier systems by podocytes, we investigated its expression in the immortalized podocyte cell lines AB8/13 and MPC-5, and in primary podocytes. Gene and protein expression analyses revealed that VCAM-1 expression is increased by podocytes upon TNFα-activation for up to 24 h. This was paralleled by anti-VCAM-1 antibody binding to the TNFα-activated cells, which can be employed as a ligand to facilitate the uptake of nanocarriers under inflammatory conditions. Hence, we next explored the possibilities of using VCAM-1 as a cell-surface receptor to deliver the potent immunosuppressant rapamycin to TNFα-activated podocytes using the lipid-based nanocarrier system Saint-O-Somes. Anti-VCAM-1-rapamycin-SAINT-O-Somes more effectively inhibited the cell migration of AB8/13 cells than free rapamycin and non-targeted rapamycin-SAINT-O-Somes indicating the potential of VCAM-1 targeted drug delivery to podocytes. PMID:26407295

[Attractiveness of France for international clinical research: 8th survey conducted by Leem (French association for pharmaceutical companies)].

PubMed

Galaup, Ariane; Barthélémy, Philippe; Pouletty-Lefebvre, Brigitte; Béhier, Jehan-Michel; Zetlaoui, Jean; Borel, Thomas

2018-04-18

The Leem (French association of pharmaceutical companies) has conducted the eighth survey on attractiveness of France for clinical research. It serves to measure France's global competitiveness for international clinical trials and assess its strengths and areas of excellence. It also highlights the potential for progress and emerging trends at a time when the regulatory environment in France and Europe is undergoing change. This survey has been updated every two years since 2002 using the same methodology. It assesses the current status of research undertaken in France by the pharmaceutical industry between January 1st 2014 and December 31st 2015. Thirty companies (62% of the French market) have participated in this 8th survey which involved 3474 centers (versus 2860 in 2014) and 16,622 patients (versus 14,634 in 2014) enrolled in France across 586 clinical trials (versus 613 in 2014). This survey shows a reduction in the number of phase I and phase II trials. It also confirms that the studies conducted in France are primarily concerned with oncology (45%). Despite improvements across hospital contracts times (due to the adoption of the sole agreement) and performance indicators in trials (such as the number of patients enrolled by center), trial setup times in France are still overly lengthy (with stable times by French authorities). Ensuring that clinical research remains a priority issue for country is crucial for patients because of rapid access to innovation but also for the vitality of the French economy. Constructive dialogue with stakeholders on the subject of clinical research is essential to enhance the attractiveness of France and to improve the continuum between research, innovation and care. Copyright © 2018 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.

Air pollution removal by trees in public green spaces in Strasbourg city, France

Treesearch

Wissal Selmi; Christiane Weber; Emmanuel Riviere; Nadege Blond; Lotfi Mehdi; David Nowak

2016-01-01

This study integrates i-Tree Eco model in order to estimate air pollution removal by urban trees in Strasbourg city, France. Applied for the first time in a French city, the model shows that public trees, i.e., trees managed by the city, removed about 88 t of pollutants during one year period (from July 2012 to June 2013): about 1 ton for CO; 14 tons for NO2...

77 FR 36213 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-18

...-0630; Directorate Identifier 2011-SW-010-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France EC130B4 helicopters... unsafe condition for the Eurocopter France EC130B4 helicopters. EASA states that it received reports that...

77 FR 36220 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-18

...-0632; Directorate Identifier 2011-SW-044-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all Eurocopter France (Eurocopter... Civil Aviation (DGAC France) AD F-2008-04, dated June 4, 2008, for the Eurocopter Model EC 155 B, EC 155...

77 FR 11787 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-28

...-0177; Directorate Identifier 2009-SW-59-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France Model EC155B and... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

78 FR 75579 - Low Enriched Uranium From France

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-12

... From France Determination On the basis of the record \\1\\ developed in the subject five-year review, the... uranium from France would be likely to lead to continuation or recurrence of material injury to an... Commission are contained in USITC Publication 4436 (December 2013), entitled Low Enriched Uranium from France...

Analysis of the effects of human activities on the hydromorphological evolution channel of the Saint-Maurice River downstream from La Gabelle dam (Quebec, Canada)

NASA Astrophysics Data System (ADS)

Vadnais, Marie-Ève; Assani, Ali A.; Landry, Raphaëlle; Leroux, Denis; Gratton, Denis

2012-11-01

During the first half of the twentieth century, many hydroelectric facilities were built in the Saint-Maurice River watershed, followed by other human activities in the second half of the century (pleasure boating, boom dismantling, urbanization, etc.). The goal of the study is to constrain the effects of these various types of human activities, particularly those of the many dams in the watershed, on the hydromorphological evolution of the Saint-Maurice River downstream from the La Gabelle (dam) power plant (43,000 km2). Comparison of specific discharge in this river with streamflow measured in a natural river setting reveals a significant decrease in seasonal maximum flows, aside from winter, when daily maximum flows increased significantly. Also, unlike natural rivers, the long-term trend in spring flows is not characterized by a significant change in mean downstream from the La Gabelle plant. These hydrological changes are linked to the inversion-type management mode of the reservoirs built downstream from the plant. As for the morphological evolution, the longitudinal variability of bankfull width downstream from the plant shows two significant shifts in mean: the first, which was quasi-abrupt, took place downstream of the des Forges rapid; and the second, which was gradual, occurred upstream from the confluence of the Saint-Maurice River with the St. Lawrence River, above the point where the Saint-Maurice splits into two branches. Comparison of aerial photographs taken at various times (1948, 1964, 1975, 1996, and 2008) reveals no significant change in the mean of bankfull width over time. However, a significant increase in the surface area of islets located at the confluence was observed, which is caused by sediment accumulation. These sediments were likely derived from local bank erosion resulting from anthropogenic changes.

CASMI TSCC Launch Event, Paris, France, July 2013: An Assessment of the Key Barriers to the Commercialization and Clinical Adoption of Pluripotent Stem Cell Therapies*

PubMed Central

Bure, Kim; Brindley, David A.

2014-01-01

Abstract The high incidence of unmet medical needs in combination with the rising burden of chronic diseases, linked to an increasingly aging population, necessitates new approaches to therapeutic intervention. One potential class of health care innovation that may offer an alternative approach to addressing current shortfalls is stem cell therapies. The CASMI Translational Stem Cell Consortium (CTSCC) was formed to elucidate the key hurdles to the commercialization and clinical adoption of stem cell technologies, with a particular focus on pluripotent stem cell (PSC) technologies. As a global pre-competitive academic–industry consortium, the CTSCC unites thought leaders from a range of sectors and technical specialties in defining and discovering solutions to roadblocks that will impede the field. Targeted toward stakeholder requirements at the delivery end of the translational spectrum, the CTSCC aims to provide mechanisms for multidirectional dialogue and to produce academically rigorous and commercially practicable research outputs to accelerate industry progress. On the 30th and 31st of July, 2013, the CASMI Translational Stem Cell Consortium (CTSCC) held a launch event at the Saint James Club, Paris, France. PMID:24392658

78 FR 9777 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-12

... Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), Department of... airworthiness directive (AD) for Eurocopter France (Eurocopter) Model EC 155B, EC155B1, SA-365N1, AS-365N2 and... aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral...

78 FR 63429 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

...-0872; Directorate Identifier 2013-SW-012-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France Model AS332C, AS332L... approved by the aviation authority of France and are approved for operation in the United States. Pursuant...

A Proposed Community Network For Monitoring Volcanic Emissions In Saint Lucia, Lesser Antilles

NASA Astrophysics Data System (ADS)

Joseph, E. P.; Beckles, D. M.; Robertson, R. E.; Latchman, J. L.; Edwards, S.

2013-12-01

Systematic geochemical monitoring of volcanic systems in the English-speaking islands of the Lesser Antilles was initiated by the UWI Seismic Research Centre (SRC) in 2000, as part of its volcanic surveillance programme for the English-speaking islands of the Lesser Antilles. This programme provided the first time-series observations used for the purpose of volcano monitoring in Dominica and Saint Lucia, permitted the characterization of the geothermal fluids associated with them, and established baseline studies for understanding of the hydrothermal systems during periods of quiescence (Joseph et al., 2011; Joseph et al., 2013). As part of efforts to improve and expand the capacity of SRC to provide volcanic surveillance through its geothermal monitoring programme, it is necessary to develop economically sustainable options for the monitoring of volcanic emissions/pollutants. Towards this effort we intend to work in collaboration with local authorities in Saint Lucia, to develop a monitoring network for quantifying the background exposure levels of ambient concentrations of volcanic pollutants, SO2 in air and As in waters (as health significant marker elements in the geothermal emissions) that would serve as a model for the emissions monitoring network for other volcanic islands. This programme would facilitate the building of local capacity and training to monitor the hazardous exposure, through the application and transfer of a regionally available low-cost and low-technology SO2 measurement/detection system in Saint Lucia. Existing monitoring technologies to inform evidence based health practices are too costly for small island Caribbean states, and no government policies or health services measures currently exist to address/mitigate these influences. Gases, aerosols and toxic elements from eruptive and non-eruptive volcanic activity are known to adversely affect human health and the environment (Baxter, 2000; Zhang et al., 2008). Investigations into the

Mercury bioaccumulation in aquatic biota along a salinity gradient in the Saint John River estuary.

PubMed

Reinhart, Bethany L; Kidd, Karen A; Curry, R Allen; O'Driscoll, Nelson J; Pavey, Scott A

2018-06-01

Although estuaries are critical habitats for many aquatic species, the spatial trends of toxic methylmercury (MeHg) in biota from fresh to marine waters are poorly understood. Our objective was to determine if MeHg concentrations in biota changed along a salinity gradient in an estuary. Fourspine Stickleback (Apeltes quadracus), invertebrates (snails, amphipods, and chironomids), sediments, and water were collected from ten sites along the Saint John River estuary, New Brunswick, Canada in 2015 and 2016, with salinities ranging from 0.06 to 6.96. Total mercury (proxy for MeHg) was measured in whole fish and MeHg was measured in a subset of fish, pooled invertebrates, sediments, and water. Stable sulfur (δ 34 S), carbon (δ 13 C), and nitrogen (δ 15 N) isotope values were measured to assess energy sources (S, C) and relative trophic level (N). There were increases in biotic δ 13 C and δ 34 S from fresh to more saline sites and these measures were correlated with salinity. Though aqueous MeHg was higher at the freshwater than more saline sites, only chironomid MeHg increased significantly with salinity. In the Saint John River estuary, there was little evidence that MeHg and its associated risks increased along a salinity gradient. Copyright © 2018. Published by Elsevier B.V.

[Comparisons outpatient drug prescriptions: France, Denmark, Norway, Sweden].

PubMed

Dezileaux, Barbara; Martinez, Florie

2016-06-01

Comparisons outpatient drug prescriptions: France, Denmark, Norway, Sweden. Project compares quantitatively outpatient drug prescriptions in France, Denmark, Norway and Sweden. Data were obtained from national databases; the unit of measurement was defined daily dose per 1000 inhabitants. The five most prescribed drug classes were compared in each country in 2009, then benzodiazepines and antibiotics from 2006 to 2012. A literature review was focused on the context of prescriptions for each country. In 2009, the five most prescribed drug classes in the four countries represented seven classes in total. France was not the biggest prescriber of drugs, but from 2006 to 2012 benzodiazepines and antibiotics were prescribed much more in France than in the other countries. The evolution of prescriptions was different for each country, and very stable in France. In 2009, France was not the biggest drugs consumer of all classes, but was characterized by high prescriptions in some classes. Copyright © 2016 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.

Does exposure to aircraft noise increase the mortality from cardiovascular disease in the population living in the vicinity of airports? Results of an ecological study in France.

PubMed

Evrard, Anne-Sophie; Bouaoun, Liacine; Champelovier, Patricia; Lambert, Jacques; Laumon, Bernard

2015-01-01

The impact of aircraft noise on health is of growing concern. We investigated the relationship between this exposure and mortality from cardiovascular disease, coronary heart disease, myocardial infarction, and stroke. We performed an ecological study on 161 communes (commune being the smallest administrative unit in France) close to the following three major French airports: Paris-Charles de Gaulle, Lyon Saint-Exupéry, and Toulouse-Blagnac. The mortality data were provided by the French Center on Medical Causes of Death for the period 2007-2010. Based on the data provided by the French Civil Aviation Authority, a weighted average exposure to aircraft noise (L den AEI) was computed at the commune level. A Poisson regression model with commune-specific random intercepts, adjusted for potential confounding factors including air pollution, was used to investigate the association between mortality rates and L den AEI. Positive associations were observed between L den AEI and mortality from cardiovascular disease [adjusted mortality rate ratio (MRR) per 10 dB(A) increase in L den AEI = 1.18; 95% confidence interval (CI): 1.11-1.25], coronary heart disease [MRR = 1.24 (1.12-1.36)], and myocardial infarction [MRR = 1.28 (1.11-1.46]. Stroke mortality was more weakly associated with L den AEI [MRR = 1.08 (0.97-1.21]. These significant associations were not attenuated after the adjustment for air pollution. The present ecological study supports the hypothesis of an association between aircraft noise exposure and mortality from cardiovascular disease, coronary heart disease, and myocardial infarction. However, the potential for ecological bias and the possibility that this association could be due to residual confounding cannot be excluded.

Does exposure to aircraft noise increase the mortality from cardiovascular disease in the population living in the vicinity of airports? Results of an ecological study in France

PubMed Central

Evrard, Anne-Sophie; Bouaoun, Liacine; Champelovier, Patricia; Lambert, Jacques; Laumon, Bernard

2015-01-01

The impact of aircraft noise on health is of growing concern. We investigated the relationship between this exposure and mortality from cardiovascular disease, coronary heart disease, myocardial infarction, and stroke. We performed an ecological study on 161 communes (commune being the smallest administrative unit in France) close to the following three major French airports: Paris-Charles de Gaulle, Lyon Saint-Exupéry, and Toulouse-Blagnac. The mortality data were provided by the French Center on Medical Causes of Death for the period 2007-2010. Based on the data provided by the French Civil Aviation Authority, a weighted average exposure to aircraft noise (Lden AEI) was computed at the commune level. A Poisson regression model with commune-specific random intercepts, adjusted for potential confounding factors including air pollution, was used to investigate the association between mortality rates and Lden AEI. Positive associations were observed between Lden AEI and mortality from cardiovascular disease [adjusted mortality rate ratio (MRR) per 10 dB(A) increase in Lden AEI = 1.18; 95% confidence interval (CI): 1.11-1.25], coronary heart disease [MRR = 1.24 (1.12-1.36)], and myocardial infarction [MRR = 1.28 (1.11-1.46]. Stroke mortality was more weakly associated with Lden AEI [MRR = 1.08 (0.97-1.21]. These significant associations were not attenuated after the adjustment for air pollution. The present ecological study supports the hypothesis of an association between aircraft noise exposure and mortality from cardiovascular disease, coronary heart disease, and myocardial infarction. However, the potential for ecological bias and the possibility that this association could be due to residual confounding cannot be excluded. PMID:26356375

77 FR 54353 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-05

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for all Eurocopter France... apply to all Eurocopter France (EC) Model SA-365N, SA-365N1, SA-366G1, AS-365N2, AS 365 N3, EC 155B, and...

“State of the Estuary” - Developing a long term monitoring, assessment and reporting framework for the lower Saint Louis River

EPA Science Inventory

As the lower Saint Louis River moves closer and closer to delisting as an Area of Concern, it is incumbent that we measure, assess and report on our success. Going forward, It’s equally important that we continue monitoring to protect and sustain the healthy ecosystems we&...

Colloquium on High Resolution Molecular Spectroscopy (8th), 19-23 September 1983 (Colloque sur la Spectroscopie Moleculaire a Haute Resolution (Huitieme), 19-23 Septembre 1983).

DTIC Science & Technology

1983-09-23

avec lea autres State. A FITTING PROCEDURE FOP EXTENSIVELY PERTURBED HAMILTONIANS APPLICATION TO THE A1I- STATE OF CO ANDRE LE FLOCH AND JEAN MASSON...BENICHOU, Jean -Claude DEROCHE Laboratoire d’Infrarouge, Associg au C.N.R.S. Universitf de Paris-Sud, Bitiment 350 91405 ORSAY Cfdex, France Le pompage...MEUDON, FRANCE and Jean -Yves RONCIN Equipe de Spectroscopie, C.N.R.S. (L.A. 171, Universitis de Lyon I et Saint-Etienne) 158 bis Cours Fauriel, 42023

A Survey of Basic Educational Opportunities Available to Members of the Church of Jesus Christ of Latter-Day Saints.

ERIC Educational Resources Information Center

Cameron, J. Elliot

To examine the historical background of educational programs of the Church of Jesus Christ of Latter-Day Saints, the Church population, and educational opportunities available to Church members, a questionnaire was sent to presidents of Church missions outside the United States. It was found that Church membership has increased rapidly and could…

Interaction between different groundwaters in brittany catchments (france): characterizing multiple sources through Sr- and S isotope tracing

NASA Astrophysics Data System (ADS)

Negrel, Ph; Pauwels, H.

2003-04-01

Water resources in hard-rocks commonly involve different hydrogeological compartments such as overlying sediments, weathered rock, the weathered-fissured zone, and fractured bedrock. Streams, lakes and wetlands that drain such environments can drain groundwater, recharge groundwater, or do both. Groundwater resources in many countries are increasingly threatened by growing demand, wasteful use, and contamination. Surface water and shallow groundwater are particularly vulnerable to pollution, while deeper resources are more protected from contamination. Sr- and S-isotope data as well as major ions, from shallow and deep groundwater in three granite and Brioverian "schist" areas of the Armorican Massif (NW France) with intensive agriculture covering large parts are presented. The stable-isotope signatures of the waters plot close to the general meteoric-water line, reflecting a meteoric origin and the lack of significant evaporation or water-rock interaction. The water chemistry from the different catchments shows large variation in the major-element contents. Plotting Na, Mg, NO_3, K, SO_4 and Sr vs. Cl contents concentrations reflect agricultural input from hog and livestock farming and fertilizer applications, with local sewage-effluent influence, although some water samples are clearly unpolluted. The δ34S(SO_4) is controlled by several potential sources (atmospheric sulphate, pyrite-derived sulphates, fertilizer sulphates). Some δ18O and δ34S values are expected to increase through sulphate reduction, with higher effect on δ34S for the dissimilatory processes and on δ18O for assimilatory processes. The range in Sr contents in groundwater from different catchments agrees with previous work on groundwater sampled from granites in France. The Sr content is well correlated with Mg and both are related to agricultural practises. As in granite-gneiss watersheds in France, 87Sr/86Sr ratios range from 0.71265 to 0.72009. The relationship between 87Sr/86Sr and Mg

Is (18)F-FDG a surrogate tracer to measure tumor hypoxia? Comparison with the hypoxic tracer (14)C-EF3 in animal tumor models.

PubMed

Christian, Nicolas; Deheneffe, Stéphanie; Bol, Anne; De Bast, Marc; Labar, Daniel; Lee, John A; Grégoire, Vincent

2010-11-01

Fluorodeoxyglucose (FDG) has been reported as a surrogate tracer to measure tumor hypoxia with positron emission tomography (PET). The hypothesis is that there is an increased uptake of FDG under hypoxic conditions secondary to enhanced glycolysis, compensating the hypoxia-induced loss of cellular energy production. Several studies have already addressed this issue, some with conflicting results. This study aimed to compare the tracers (14)C-EF3 and (18)F-FDG to detect hypoxia in mouse tumor models. C3H, tumor-bearing mice (FSAII and SCCVII tumors) were injected iv with (14)C-EF3, and 1h later with (18)F-FDG. Using a specifically designed immobilization device with fiducial markers, PET (Mosaic®, Philips) images were acquired 1h after the FDG injection. After imaging, the device containing mouse was frozen, transversally sliced and imaged with autoradiography (AR) (FLA-5100, Fujifilm) to obtain high resolution images of the (18)F-FDG distribution within the tumor area. After a 48-h delay allowing for (18)F decay a second AR was performed to image (14)C-EF3 distribution. AR images were aligned to reconstruct the full 3D tumor volume, and were compared with the PET images. Image segmentation with threshold-based methods was applied on both AR and PET images to derive various tracer activity volumes. The matching index DSI (dice similarity index) was then computed. The comparison was performed under normoxic (ambient air, FSAII: n=4, SCCVII, n=5) and under hypoxic conditions (10% O(2) breathing, SCCVII: n=4). On AR, under both ambient air and hypoxic conditions, there was a decreasing similarity between (14)C-EF3 and FDG with higher activity sub-volumes. Under normoxic conditions, when comparing the 10% of tumor voxels with the highest (18)F-FDG or (14)C-EF3 activity, a DSI of 0.24 and 0.20 was found for FSAII and SCCVII, respectively. Under hypoxic conditions, a DSI of 0.36 was observed for SCCVII tumors. When comparing the (14)C-EF3 distribution in AR with the

Vocational Education and Training in France.

ERIC Educational Resources Information Center

Willems, Jean-Pierre

This monograph gives an overview of the vocational education and training system in France. It contains the following information: (1) a presentation of the administrative, demographic, and economic background in which the training system in France exists; (2) a brief historical review of the development of the training systems; (3) a presentation…

Evolution of high-rise construction in Leningrad - Saint Petersburg in the middle of the 20th - Early 21st centuries: projects and Implementation

NASA Astrophysics Data System (ADS)

Vaytens, Andrey; Rusanov, Gennadiy; Skryabin, Pavel

2018-03-01

One of the most important issues in national urban planning is arrangement of high-rise buildings in the largest cities of Russia. This issue becomes especially acute in such cities as Saint Petersburg, which has unique architectural and urban-planning heritage preserved to a great extent. In this regard, it seems important to trace the evolution of high-rise construction development and arrangement in Leningrad - Saint Petersburg in the middle of the 20th — early 21st centuries. The goal of the article is to consider high-rise construction development regarding both public and residential buildings in comparison of project ideas and results of their implementation in the 1940s-2000s. Prerequisites and issues of high-rise construction of that period are considered. Particular attention is paid to changes in the official urban-planning policy, regulatory framework and attitude of city authorities to high-rise construction. The study was carried out with the consideration of the following historic periods differing in their urban-planning policy: the late 1940s-1950s; 1960s; 1970-1980s; 1990s; 2000s-2010s. Economical prerequisites of high-rise construction and their influence on the modern urban-planning policy during the post-Soviet period are considered. In conclusion, an attempt is made to determine tendencies of high-rise construction development in Saint Petersburg.

Saint Lawrence Seaway Navigation-Aid System Study : Volume II - Appendix B - User's Manual and Documentation of Seaway Capacity and Capacity Analysis Programs

DOT National Transportation Integrated Search

1978-09-01

The requirements for a navigation guidance system which will effect an increase in the ship processing capacity of the Saint Lawrence Seaway (Lake Ontario to Montreal, Quebec) are developed. The requirements include a specification of system position...

Saint Lawrence Seaway Navigation-Aid System Study : Volume III - Appendix C - User's Manual and Documentation of the Ship Maneuvering Requirements Computer Program

DOT National Transportation Integrated Search

1978-09-01

The requirements for a navigation guidance system which will effect an increase in the ship processing capacity of the Saint Lawrence Seaway (Lake Ontario to Montreal, Quebec) are developed. The requirements include a specification of system position...

Isotope tools to support conceptual model building of the Carboniferous limestone aquifer of Northern France and Belgium

NASA Astrophysics Data System (ADS)

Gourcy, L.; Castres de Paulet, F.; Rorive, A.; Bastien, J.

2012-04-01

Since the beginning of the 20th century, the Carboniferous aquifer was known as a high potential limestone aquifer. Groundwater has been exploited for decades to provide drinkable water and supply heavy factories in north of France and Belgium. Over-pumped during the last century, the Carboniferous aquifer has seen its water level dramatically decreased between Lille (Fr), Mouscron and Tournai (Be). Since the end of industrial period and some agreements to reduce pumpings, groundwater consumption has declined and water table is now stabilized and slowly coming back to a more "natural" level in some areas. In order to sustainably manage this aquifer, French and Belgian environmental agencies and local authorities underlined the need of a better hydrogeological knowledge. Within the framework of the "Scaldwin" project (launched in 2008), a hydrogeological model will be built. To reach these objectives, existing data were compiled, updated and treated. Moreover, new data were collected since 2009: 11 boreholes were drilled, 2 piezometrical maps were drawn and 2 field sampling campaigns were carried out in March and November 2011 to collect groundwater for further analyses. As a first step, the conceptual hydrogeological map was reviewed considering new knowledge of the geometry and water levels of this aquifer. Then, the hydrogeochemical study was undertaken in order to dispel doubts on some specific aspects such as: relationships between the deep (carbonated Carboniferous) and the surface (chalky Cretaceous) aquifers, delineation of the southern Carboniferous aquifer limit, mechanisms of sulphate enrichment… Major and trace elements, dissolved gases (CFC-11, CFC-12, CFC-113, SF6) and various isotopes (δ2H, δ18O, δ11B, δ34S, δ18O-SO4, δ13C, 14C) were analysed in water sampled from 36 wells exploiting the Carboniferous limestones (16 in the French part and 20 in Belgium) and 4 waters from the chalk aquifer. Cation exchange process is playing an important role

78 FR 60681 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-02

... Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters AGENCY: Federal Aviation Administration... helicopters have been approved by the aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical representative, has...

Occupational external exposure to ionising radiation in France (2005-2011).

PubMed

Feuardent, J; Scanff, P; Crescini, D; Rannou, A

2013-12-01

The Institute for Radiological Protection and Nuclear Safety (IRSN) produces the French annual report on occupational exposure to ionising radiation, collecting all national data and aggregating the results according to a unique activity classification expected to be shared by all involved in personal dosimetric monitoring (employers, external dosimetry services and IRSN). Nearly 344,000 monitored workers were counted in France in 2011, with a collective dose of 64.24 man.Sv. The average annual dose (as calculated over the number of measurably exposed workers) differed among the main activity fields: 0.54 mSv in medical and veterinary activities, 1.18 mSv in the nuclear field, 1.60 mSv in non-nuclear industry and 0.47 mSv in research activities. Because of improved knowledge about worker activities, the results for year 2011 are detailed per activity sectors in each field. Lasting limitations prevent from having complete and reliable worker activity information. Solutions are considered to reduce the inaccuracy in the annually published statistics. The evolution of occupational external exposure to ionising radiation from 2005 to 2011 in France is then presented for the main activity fields.

Reconstruction of a saline, lacustrine carbonate system (Priabonian, St-Chaptes Basin, SE France): Depositional models, paleogeographic and paleoclimatic implications

NASA Astrophysics Data System (ADS)

Lettéron, Alexandre; Hamon, Youri; Fournier, François; Séranne, Michel; Pellenard, Pierre; Joseph, Philippe

2018-05-01

A 220-m thick carbonate-dominated succession has been deposited in shallow-water, saline lake environments during the early to middle Priabonian (MP17A-MP18 mammal zones) in the Saint-Chaptes Basin (south-east France). The palaeoenvironmental, paleoclimatic and palaeogeographic significance of such saline lake carbonates has been deciphered on the basis of a multi-proxy analyses including: 1) depositional and diagenetic features; 2) biological components (molluscs, benthic foraminifera, characean gyrogonites, spores and pollens); 3) carbon and oxygen stable isotopes; 4) trace elements; and 5) clay mineralogy. Five stages of lacustrine system evolution have been identified: 1) fresh-water closed lake under dry climate (unit U1); 2) fresh to brackish water lacustrine deltaic system with a mixed carbonate-siliciclastic sedimentation under relatively wet climatic conditions (unit U2); 3) salt-water lacustrine carbonate system under humid climatic setting (unit U3); 4) evaporitic lake (unit U4); and 5) closed lake with shallow-water carbonate sedimentation under subtropical to Mediterranean climate with dry seasons (unit U5). Upper Eocene aridification is evidenced to have started as early as the earliest Priabonian (unit U1: MP17A mammal zone). A change from humid to dryer climatic conditions is recorded between units U3 and U4. The early to middle Priabonian saline lake is interpreted as an athalassic (inland) lake that have been transiently connected with neighboring salt lakes influenced by seawater and/or fed with sulfates deriving from recycling of evaporites. Maximum of connection with neighboring saline lakes (Mormoiron Basin, Camargue and Central grabens, Hérault Basin) likely occurred during unit U3 and at the base of unit U5. The most likely sources of salts of these adjacent basins are: 1) Triassic evaporites derived from salt-diapirs (Rhône valley) or from paleo-outcrops located east of the Durance fault or offshore in the Gulf of Lion; or 2) marine

78 FR 60188 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-01

... Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters AGENCY: Federal Aviation Administration... aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical representative, has notified us of the unsafe condition described...

78 FR 63853 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

... Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters AGENCY: Federal Aviation Administration... aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical representative, has notified us of the unsafe condition described...

10 years of surveillance of human tularaemia in France.

PubMed

Mailles, A; Vaillant, V

2014-11-13

Tularaemia has been mandatorily notifiable in France since October 2002. The surveillance aims to detect early any infection possibly due to bioterrorism and to follow up disease trends. We report the results of national surveillance from 2002 to 2012. A case is defined as a patient with clinical presentation suggestive of tularaemia and biological confirmation of infection or an epidemiological link with a biologically confirmed case. Clinical, biological and epidemiological data are collected using a standardised notification form. From 2002 to 2012, 433 cases were notified, with a median age of 49 years (range 2 to 95 years) and a male–female sex ratio of 1.8. Most frequent clinical presentations were glandular tularaemia (n=200; 46%) and ulceroglandular tularaemia (n=113; 26%). Most frequent at-risk exposures were handling hares (n=179; 41%) and outdoor leisure exposure to dust aerosols (n=217; 50%). Tick bites were reported by 82 patients (19%). Ten clusters (39 cases) were detected over the 10-year period, as well as a national outbreak during winter 2007/2008. The tularaemia surveillance system is able to detect small clusters as well as major outbreaks. Surveillance data show exposure to dust aerosols during outdoor leisure activities to be a major source of contamination in France.

18 CFR 300.14 - Filings under section 7(k).

Code of Federal Regulations, 2011 CFR

2011-04-01

...(k). 300.14 Section 300.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... section 7(k). Any application for Commission review and approval of a rate or rate schedules established by the Administrator of the Bonneville Power Administration pursuant to section 7(k) of the Pacific...

18 CFR 300.14 - Filings under section 7(k).

Code of Federal Regulations, 2014 CFR

2014-04-01

...(k). 300.14 Section 300.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... section 7(k). Any application for Commission review and approval of a rate or rate schedules established by the Administrator of the Bonneville Power Administration pursuant to section 7(k) of the Pacific...

18 CFR 300.14 - Filings under section 7(k).

Code of Federal Regulations, 2013 CFR

2013-04-01

...(k). 300.14 Section 300.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... section 7(k). Any application for Commission review and approval of a rate or rate schedules established by the Administrator of the Bonneville Power Administration pursuant to section 7(k) of the Pacific...

18 CFR 300.14 - Filings under section 7(k).

Code of Federal Regulations, 2012 CFR

2012-04-01

...(k). 300.14 Section 300.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... section 7(k). Any application for Commission review and approval of a rate or rate schedules established by the Administrator of the Bonneville Power Administration pursuant to section 7(k) of the Pacific...

18 CFR 300.14 - Filings under section 7(k).

Code of Federal Regulations, 2010 CFR

2010-04-01

...(k). 300.14 Section 300.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... section 7(k). Any application for Commission review and approval of a rate or rate schedules established by the Administrator of the Bonneville Power Administration pursuant to section 7(k) of the Pacific...

Demonstration of monolignol β-glucosidase activity of rice Os4BGlu14, Os4BGlu16 and Os4BGlu18 in Arabidopsis thaliana bglu45 mutant.

PubMed

Baiya, Supaporn; Mahong, Bancha; Lee, Sang-Kyu; Jeon, Jong-Seong; Ketudat Cairns, James R

2018-06-01

The glycoside hydrolase family 1 members Os4BGlu14, Os4BGlu16, and Os4BGlu18 were proposed to be rice monolignol β-glucosidases. In vitro studies demonstrated that the Os4BGlu16 and Os4BGlu18 hydrolyze the monolignol glucosides coniferin and syringin with high efficiency compared to other substrates. The replacement of the conserved catalytic acid/base glutamate residue by a nonionizable glutamine residue in Os4BGlu14 suggested that it may be inactive as a β-glucosidase. Here, we investigated the activities of Os4BGlu14, Os4BGlu16, and Os4BGlu18 in planta by recombinant expression of their genes in the Arabidopsis bglu45-2 (monolignol β-glucosidase) mutant and analysis of monolignol glucosides by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MSMS). The bglu45-2 line exhibits elevated monolignol glucoside levels, but lower amounts of coniferin, syringin, and p-coumaryl alcohol glucoside were seen in Arabidopsis bglu45-2 rescued lines complemented by the Os4BGlu14, Os4BGlu16, and Os4BGlu18 genes. These data suggest that the bglu45-2 mutant has a broader effect on monolignols than previously reported and that the Os4BGlu14, Os4BGlu16 and Os4BGlu18 proteins act as monolignol β-glucosidases to complement the defect. An OsBGlu16-GFP fusion protein localized to the cell wall. This apoplastic localization and the effect of these enzymes on monolignol glucoside levels suggest monolignol glucosides from the vacuole may meet the monolignol β-glucosidases, despite their different localization. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

77 FR 16137 - Airworthiness Directives; Eurocopter France Model Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

... Airworthiness Directives; Eurocopter France Model Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for the Eurocopter France... directive (AD): 2012-05-01 Eurocopter France: Amendment 39-16973; Docket No. FAA- 2011-0454; Directorate...

Inflammatory response and treatment tolerance of long-term infusion of the anti-GD2 antibody ch14.18/CHO in combination with interleukin-2 in patients with high-risk neuroblastoma.

PubMed

Ceylan, Kiraz; Jahns, Luciana J; Lode, Bjoern N; Ehlert, Karoline; Kietz, Silke; Troschke-Meurer, Sascha; Siebert, Nikolai; Lode, Holger N

2018-06-01

The monoclonal anti-GD 2 antibody ch14.18/CHO in combination with IL-2 is active and effective in high-risk neuroblastoma (NB) patients. Here, we investigated the inflammatory response and treatment tolerance of long-term infusion (LTI) of ch14.18/CHO (10 × 10 mg/m 2 ; 24 hr) in combination with subcutaneous (s.c.) IL-2 in a single center program. Fifty-three NB patients received up to six cycles of 100 mg/m 2 ch14.18/CHO (d8-18, where d represents day(s)) as LTI combined with 6 × 10 6 IU/m 2 s.c. IL-2 (d1-5; 8-12) and 160 mg/m 2 oral 13-cis retinoic acid (RA) (d19-32). Side effects of ch14.18/CHO and IL-2 treatment require hospitalization of patients on d8. Treatment tolerance was evaluated daily with clinical parameters (body temperature, vital signs, Lansky performance status, requirement of i.v. concomitant medication) to define an outpatient candidate status. sIL-2-R and C-reactive protein values were determined to assess the inflammatory response. LTI of ch14.18/CHO (d8-18) in combination with s.c.IL-2 (d8-12) showed an acceptable treatment tolerance that allowed all patients to receive part of the treatment as an outpatient (median time point of discharge: d15 for all cycles). The treatment tolerance improved from cycle to cycle and the time to become an outpatient candidate decreased from d15 to d13 in subsequent cycles. Clinical and laboratory parameters indicate a maximum inflammatory response at d11 of each cycle. Interestingly, the soluble IL-2 receptor remained increased at baseline of the next cycle indicating immune activation over the entire treatment period of 6 months. LTI of ch14.18/CHO combined with s.c.IL-2 shows an improved tolerance in subsequent cycles allowing outpatient treatment. © 2018 Wiley Periodicals, Inc.

Direct medical costs associated with the extrahepatic manifestations of hepatitis C virus infection in France.

PubMed

Cacoub, P; Vautier, M; Desbois, A C; Saadoun, D; Younossi, Z

2018-01-01

The economic impact of extrahepatic manifestations of hepatitis C virus (HCV) infection remains unknown for France. To estimate the prevalence of extrahepatic manifestations of HCV and the direct medical costs associated with them. Estimates of 13 extrahepatic manifestations prevalence were obtained from (1) a retrospective data analysis of HCV-infected patients in a specialised centre and the baseline prevalence in the general French population and (2) an international systematic review. Per-patient-per-year costs to treat these manifestations were obtained from the literature, national databases or expert opinion. The impact of achieving HCV cure after anti-viral therapy was applied to the French healthcare costs. Using approach (1), increased prevalence rates in HCV patients compared to the general population were observed for most extrahepatic manifestations. The mean per-patient-per-year cost of these manifestations in the tertiary centre was 3296 € [95% CI 1829; 5540]. In France, HCV-extrahepatic manifestations amounted to a total cost of 215 million (M) € per year [144; 299]. Using approach (2), the mean per-patient-per-year cost was estimated to be 1117 €. The estimated total cost reduction in France associated with HCV cure was 13.9 M€ for diabetes, 8.6 M€ for cryoglobulinemia vasculitis, 6.7 M€ for myocardial infarction, 2.4 M€ for end-stage renal disease and 1.4 M€ for stroke. Extrahepatic manifestations of HCV infection substantially add to the overall economic burden of the disease in France. HCV cure after anti-viral therapy is expected to significantly reduce the total costs of managing these manifestations in France. © 2017 John Wiley & Sons Ltd.

From Science to Industry: The Sites of Aluminium in France from the Nineteenth to the Twentieth Century.

PubMed

Le Roux, Muriel

2015-05-01

This paper explores the history of the isolation and industrial production of aluminium in France, from the work of Henri Sainte-Claire Deville in the 1850s to the latter part of the twentieth century, focusing on the relationships between academic research and industrial exploitation. In particular, it identifies a culture and organisation of research and development, "learning-by-doing," that emerged in the French aluminium industry following the establishment of the first electrolytic production facilities in the late 1880s by Paul Héroult, who, along with the American Charles Hall, patented the electrolytic method of producing the metal. This French method of R&D was a product both of a scientific culture that saw a continuity between scientific research and industrial application, and of a state policy that, unlike in Germany or the United States, was late to recognise the importance of fostering, on a large scale, the relations between academic chemistry and industry. It was only after World War II that the French state came fully to recognise the importance of underpinning industry with scientific research. And it was only from the 1960s, in the face of intensifying global competition, the risks of pollution, and the cost of energy, that the major aluminium firm Pechiney et Cie was able to replace a culture of "learning-by-doing" by one that integrated fundamental science with the production process.

78 FR 34960 - Airworthiness Directives; Eurocopter France Model Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-11

...-0501; Directorate Identifier 2011-SW-036-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... rulemaking (NPRM). SUMMARY: We propose to adopt a new airworthiness directive (AD) for Eurocopter France... Determination These helicopters have been approved by the aviation authority of France and are approved for...

78 FR 66668 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-06

...-0938; Directorate Identifier 2012-SW-057-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... Determination These helicopters have been approved by the aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical...

78 FR 33766 - Airworthiness Directives; Eurocopter France (Eurocopter) Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-05

...-0480; Directorate Identifier 2012-SW-090-AD] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... approved by the aviation authority of France and are approved for operation in the United States. Pursuant to our bilateral agreement with France, EASA, its technical representative, has notified us of the...

50 CFR Figure 17 to Part 679 - Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA)

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA) 17 Figure 17 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES OF THE EXCLUSIVE...

50 CFR Figure 17 to Part 679 - Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA)

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA) 17 Figure 17 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES OF THE EXCLUSIVE...

50 CFR Figure 17 to Part 679 - Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA)

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA) 17 Figure 17 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES OF THE EXCLUSIVE...

50 CFR Figure 17 to Part 679 - Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA)

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 13 2013-10-01 2013-10-01 false Northern Bering Sea Research Area and Saint Lawrence Island Habitat Conservation Area (HCA) 17 Figure 17 to part 679 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES OF THE EXCLUSIVE...

Characteristics of patients with fibromyalgia in France and Germany.

PubMed

Perrot, S; Winkelmann, A; Dukes, E; Xu, X; Schaefer, C; Ryan, K; Chandran, A; Sadosky, A; Zlateva, G

2010-07-01

Few studies have comprehensively assessed the burden associated with fibromyalgia (FM). This cross-sectional, observational study evaluates the impact of FM on patients in France and Germany. A total of 299 FM patients were recruited from 33 physician offices in France and Germany during routine visits. Patients completed a survey that included the Brief Pain Inventory-Short Form (BPI-sf), Fibromyalgia Impact Questionnaire (FIQ), EuroQol 5D (EQ-5D) and the Hospital Anxiety and Depression Scale (HADS) to describe their pain, FM and health-related quality of life (HRQOL). FM severity was defined using patients' FIQ total scores with 0 to < 39, 39 to < 59 and 59-100, representing mild, moderate and severe FM, respectively. Site staff completed case report forms using patients' medical records. Mean (standard deviation, SD) age was 54.2 (12.6); 81% of patients were women. The mean (SD) FIQ total score was 53.3 (19.6); 33% and 44% of patients reported moderate and severe FM, respectively. Most patients (91%) were receiving prescription medications for FM during the study. Patients reported a mean (SD) EQ-5D health state valuation of 0.44 (0.33) and a mean (SD) BPI-sf Pain Severity Index score of 4.9 (1.8). Forty-one percent of patients reported some level of disruption in their employment because of FM; employed patients missed a mean (SD) of 2.2 (4.6) workdays during the past 4 weeks. An increase in FM severity was significantly associated with increased pain severity, productivity loss, sleep disturbance and higher anxiety and depression (p < 0.0001). There is a substantial burden of illness including treatment limitations for FM patients in France and Germany.

18 CFR 5.14 - Formal study dispute resolution process.

Code of Federal Regulations, 2012 CFR

2012-04-01

... dispute, the panel shall make and deliver to the Director of the Office of Energy Projects a finding, with... from the date of filing of the notice of study dispute, the Director of the Office of Energy Projects... resolution process. 5.14 Section 5.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY...

18 CFR 5.14 - Formal study dispute resolution process.

Code of Federal Regulations, 2014 CFR

2014-04-01

... dispute, the panel shall make and deliver to the Director of the Office of Energy Projects a finding, with... from the date of filing of the notice of study dispute, the Director of the Office of Energy Projects... resolution process. 5.14 Section 5.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY...

18 CFR 5.14 - Formal study dispute resolution process.

Code of Federal Regulations, 2013 CFR

2013-04-01

... dispute, the panel shall make and deliver to the Director of the Office of Energy Projects a finding, with... from the date of filing of the notice of study dispute, the Director of the Office of Energy Projects... resolution process. 5.14 Section 5.14 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY...

Typology of Self-Concept of Adolescents in France: A Comparison of Gifted and Nongifted French High School Students

ERIC Educational Resources Information Center

Villatte, Aude; Courtinat-Camps, Amélie; de Léonardis, Myriam

2014-01-01

This study sought comprehension of several specifics concerning the self-concept of gifted high school students in France. Eighty-four gifted high school students (IQ = 130) between the ages of 13 and 18 were matched with 84 nongifted high school students possessing the same gender, family background, and academic characteristics. Each of these…

A surgical sabbatical in France.

PubMed

Sutherland, F; Launois, B

2000-06-01

During my stay in France I had the unique opportunity to meet surgical professors from all over the world and made many friends and contacts in the field of hepatobiliary surgery. Brittany is a beautiful province of France, having unique way of life and approach to social and societal problems. The cultural enrichment that I received from my year there will last a lifetime, as well the many fond memories of the people, the culinary delights and the spectacular seashore.

France.

PubMed

1987-09-01

In 1986, France had a population of 55,493,000, with an annual growth rate of 0.4%. The infant mortality rate stood at 8.2/1000. Of the work force of 23.8 million, 8.3% were engaged in agriculture, 45.2% were in the industry and commerce sector, and 46.5% were engaged in services. The unemployment rate stood at 10.7%. The country's gross domestic product (GDP) was US$724 billion in 1986, with an average annual growth rate of 2.0%, and per capita income averaged $13,046. France has substantial agricultural resources, a diversified modern industrial system, and a highly skilled labor force. Following the return of a socialist majority in government in 1981, several large manufacturing firms were nationalized along with much of the commercial banking sector. Initial socialist policies were stimulative, relying partly on income redistribution and partly on increased government spending. However, the resultant increase in import demand was not offset by an increased demand French exports. In 1983, an economic stabilization plan of reductions in the budget deficit, involving spending cuts, increased taxes, and tighter monetary and credit policies, was successfully implemented. Although current economic policies should promote stronger growth over the medium to long term, trade competitiveness remains weak and high unemployment is a major social problem.

Evaluation of the smoking ban in public places in France one year and five years after its implementation: Findings from the ITC France survey

PubMed Central

Fong, Geoffrey T.; Craig, Lorraine V.; Guignard, Romain; Nagelhout, Gera E.; Tait, Megan K.; Driezen, Pete; Kennedy, Ryan David; Boudreau, Christian; Wilquin, Jean-Louis; Deutsch, Antoine; Beck, François

2013-01-01

France implemented a comprehensive smoke-free policy in public places in February 2007 for workplaces, shopping centres, airports, train stations, hospitals and schools. On January 2008, it was extended to meeting places (bars, restaurants, hotels, casinos, nightclubs). This paper evaluates France’s smoke-free law based on the International Tobacco Control Policy Evaluation Project in France (the ITC France Project), which conducted a cohort survey of approximately 1,500 smokers and 500 non-smokers before the implementation of the laws (Wave 1, conducted December 2006 to February 2007) and two waves after the implementation (Wave 2, conducted between September-November 2008; and Wave 3, conducted between September-December 2012). Results show that the smoke-free law led to a very significant and near total elimination of indoor smoking in key venues such as bars (from 95.9% to 3.7%) and restaurants (from 64.7% to 2.3%) at Wave 2, which was sustained four years later at Wave 3 (1.4% in restaurants; 6.6% in bars). Smoking in workplaces declined significantly after the law (from 42.6% to 19.3%), which continued to decline at Wave 3 (to 12.8%). Support for the smoke-free law increased significantly after their implementation and continued to increase at Wave 3 (among smokers for bars and restaurants; among smokers and non-smokers for workplaces). The findings demonstrate that smoke-free policies that are implemented in ways consistent with the Guidelines for Article 8 of the WHO Framework Convention on Tobacco Control (WHO FCTC) lead to substantial and sustained reductions in tobacco smoke in public places while also leading to high levels of support by the public. PMID:24803715

Effect of Laser Powder Bed Fusion Parameters on the Microstructure and Texture Development in Superelastic Ti-18Zr-14Nb Alloy

NASA Astrophysics Data System (ADS)

Kreitcberg, A.; Brailovski, V.; Sheremetyev, V.; Prokoshkin, S.

2017-12-01

The effect of different laser powder bed fusion (L-PBF) parameters on the phase composition, microstructure, and crystallographic texture of Ti-18Zr-14Nb alloy was studied. Two levels of laser power, scanning speed, and hatching space were used, while the layer thickness was kept constant. The resulting volume energy density was ranged from 20 to 60 J/mm3, and the build rate, from 12 to 36 cm3/h. The manufactured coupons were analyzed by X-ray diffractometry, transmission, and scanning electron microscopy. It was found that the greater influence observed on the microstructure and texture development was caused by the value of laser power, while the lowest, by that of hatching space. Based on the results obtained, the processing optimization strategy aimed at improving the density, superelastic, and fatigue properties of the L-PBF manufactured Ti-18Zr-14Nb alloy was proposed.

Beginning of Viniculture in France

NASA Technical Reports Server (NTRS)

McGovern, Patrick E.; Luley, Benjamin P.; Rovira, Nuria; Mirzoian, Armen; Callahan, Michael P.; Smith, Karen F.; Hall, Gretchen R.; Davidson, Theodore; Henkin, Joshua M.

2013-01-01

Chemical analyses of ancient organic compounds absorbed into the pottery fabrics of imported Etruscan amphoras (ca. 500-475 B.C.) and into a limestone pressing platform (ca. 425-400 B.C.) at the ancient coastal port site of Lattara in southern France provide the earliest biomolecular archaeological evidence for grape wine and viniculture from this country, which is crucial to the later history of wine in Europe and the rest of the world. The data support the hypothesis that export of wine by ship from Etruria in central Italy to southern Mediterranean France fueled an ever-growing market and interest in wine there, which, in turn, as evidenced by the winepress, led to transplantation of the Eurasian grapevine and the beginning of a Celtic industry in France. Herbal and pine resin additives to the Etruscan wine point to the medicinal role of wine in antiquity, as well as a means of preserving it during marine transport.

Beginning of viniculture in France

PubMed Central

McGovern, Patrick E.; Luley, Benjamin P.; Rovira, Nuria; Mirzoian, Armen; Callahan, Michael P.; Smith, Karen E.; Hall, Gretchen R.; Davidson, Theodore; Henkin, Joshua M.

2013-01-01

Chemical analyses of ancient organic compounds absorbed into the pottery fabrics of imported Etruscan amphoras (ca. 500–475 B.C.) and into a limestone pressing platform (ca. 425–400 B.C.) at the ancient coastal port site of Lattara in southern France provide the earliest biomolecular archaeological evidence for grape wine and viniculture from this country, which is crucial to the later history of wine in Europe and the rest of the world. The data support the hypothesis that export of wine by ship from Etruria in central Italy to southern Mediterranean France fueled an ever-growing market and interest in wine there, which, in turn, as evidenced by the winepress, led to transplantation of the Eurasian grapevine and the beginning of a Celtic industry in France. Herbal and pine resin additives to the Etruscan wine point to the medicinal role of wine in antiquity, as well as a means of preserving it during marine transport. PMID:23733937

High School Geography Project. Legacy for the Seventies. An Analysis of the High School Geography Project in Relation to New Developments in Geographic Education Worldwide.

ERIC Educational Resources Information Center

Gunn, Angus M., Ed.

Nine articles by geographers and educators analyze the High School Geography Project (HSGP). A project overview by Angus Gunn presents essential ideas and content of six units and several preliminary reactions. The question of "HSGP exportability" to France and Germany is examined in articles by Maurice Saint-Yves and Robert Geipel…

Nutrient Status and Criteria Development for the Saint John River, Canada, Using a Weight of Evidence Approach

NASA Astrophysics Data System (ADS)

Culp, J. M.; Luiker, E. A.; Noel, L.; Curry, A. R.; Hryn, D.; Heard, K.

2005-05-01

The Saint John River is the largest in Maine/New Brunswick (673 km in length, draining 55,000 km2) with a history of natural resource use and nutrient effluent release to the watershed since the late 17th century. Our objective was to obtain a basic understanding of the contemporary nutrient conditions of the non-tidal portion of the river in relation to historical conditions, and to consider how the contemporary river is affected by point and non-point source nutrient loadings. The study included review of historical provincial and federal water quality databases dating back to the 1960s. Current water quality monitoring programs have focused on nitrogen (nitrite, nitrate, ammonia, TKN), phosphorus (total, dissolved, and soluble reactive phosphorus), DIC/DOC, and biomass of periphyton and phytoplankton. To determine nutrient limitation, nutrient diffusing substrate studies were conducted in river reaches of known nutrient enrichment. Oxygen stable isotopes were also used to provide information on the photosynthesis to respiration ratio. A weight of evidence approach combining the results of these studies was used to determine trophic status of river reaches and to highlight areas of eutrophication. From this information nutrient criteria for the Saint John River will be proposed.

Characterization of the first true coaxial 18-fold segmented n-type prototype HPGe detector for the GERDA project

NASA Astrophysics Data System (ADS)

Abt, I.; Caldwell, A.; Gutknecht, D.; Kröninger, K.; Lampert, M.; Liu, X.; Majorovits, B.; Quirion, D.; Stelzer, F.; Wendling, P.

2007-07-01

The first true coaxial 18-fold segmented n-type HPGe prototype detector produced by Canberra-France for the GERDA neutrinoless double beta-decay project was tested both at Canberra-France and at the Max-Planck-Institut für Physik in Munich. The main characteristics of the detector are given and measurements concerning detector properties are described. A novel method to establish contacts between the crystal and a Kapton cable is presented.

[Frequency and costs of hospital stays for hypoglycemia in France in 1995].

PubMed

Allicar, M P; Mégas, F; Houzard, S; Baroux, A; Le Thai, F; Augendre-Ferrante, B

2000-04-01

Diabetes is a highly prevalent chronic disease causing serious complications. Hypoglycemia is the most frequent, the most serious, and the most feared by patients and families. Hospitalization may be necessary and can be costly. The main objective of this study was to determine the number of cases of hypoglycemia cared for annually in France in an inpatient setting and to estimate the annual financial impact of hospitalizations. The number of hypoglycemias seen annually by physician s in France and the frequencies of hospitalizations for hypoglycemia were determined from a literature search. Complementary data on costs were obtained from the national PMSI mission. Our sample included 817 hospital stays between 1994 and 1995. In 1992, physicians in France cared for 40,000 episodes of hypoglycemia. There were 10,800 hospitalizations. In 9 out of 10 cases, the hospital stay lasted several days and, despite hospitalization, 1.9% of the patients died. Mean total medical cost of a hospital stay for hypoglycemia was 14,000 FF ($2,100) (median 10,000 FF, range 1,200-120,000 FF). Mean length of stay was 6.6 days. Mean unit cost for hospital stays for hypoglycemia is high. Based on the 1993 SESI survey, the probable annual cost for the society for hospital care of patients with hypoglycemia was an estimated 108 to 151 million FF ($16-22 million) in 1995. This figure only takes into account the visible cost of caring for hypoglycemia patients. Ambulatory care was not taken into consideration. Education, for the patient and family, is fundamental for the prevention and treatment of hypoglycemia. It is important to have this estimation due to the absence of a medicoeconomic study on ambulatory and hospital care for hypoglycemia. Complementary studies should be conducted to estimate the total annual cost of hypoglycemia in France.

Human Papillomavirus vaccination in general practice in France, three years after the implementation of a targeted vaccine recommendation based on age and sexual history.

PubMed

Thierry, Pascale; Lasserre, Andrea; Rossignol, Louise; Kernéis, Solen; Blaizeau, Fanette; Stheneur, Chantal; Blanchon, Thierry; Levy-Bruhl, Daniel; Hanslik, Thomas

2016-01-01

In France, vaccination against human papilloma virus (HPV) was recommended in 2007 for all 14-year-old girls as well as "catch-up" vaccination for girls between 15-23 y of age either before or within one year of becoming sexually active. We evaluated the vaccine coverage according to the eligibility for vaccination in a sample of young girls aged 14 to 23 years, who were seen in general practices. A survey was proposed to 706 general practitioners (GPs) and carried out from July to September 2010. GPs, also called "family doctor," are physicians whose practice is not restricted to a specific field of medicine but instead covers a variety of medical problems in patients of all ages. Each participating GP included, retrospectively, the last female patient aged 14-17 y and the last female patient aged 18-23 y whom he had seen. A questionnaire collected information regarding the GP and the patients' characteristics. The vaccine coverage was determined according to the eligibility for vaccination, i.e. the coverage among younger women (14-17) and among those sexually active in the second age range (18-23). Sexual activity status was assessed by GP, according to information stated in the medical record. The 363 participating physicians (response rate 51.4%) included 712 patients (357 in the 14- to 17-year-old group and 355 in the 15- to 23-year-old group) in their responses. The rate of the vaccination coverage in the 14- to 17-year-old group was 55%. Among the girls in the 18- to 23-year-old group, 126 were eligible, and their vaccination coverage rate was 82%. The evaluation of the eligibility by the GPs was incorrect in 36% of the cases. Of the 712 patients, 6% of the girls had been vaccinated without a need for the vaccination, and 26% of the girls had not been vaccinated, although they needed to be vaccinated. Regarding the vaccine uptake, vaccination at the age of 14 was not as effective as vaccinating the older population for which vaccination was indicated as a

78 FR 49115 - Airworthiness Directives; Eurocopter France Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-13

... Airworthiness Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT... published in the Federal Register. The AD applies to certain Eurocopter France (Eurocopter) Model AS350B3...

Parasites of the digestive tract in beef cattle imported from France to Italy.

PubMed

Stancampiano, L; Corradini, D; Bulgarelli, M; Micagni, G; Battelli, G

2007-06-01

Beef cattle heads (195 heads, 6 batches) imported for fattening from France to Italy were examined. Coprological qualitative and quantitative tests were performed, and the results analysed in relation to sex, breed, age, date of arrival, geographical origin (French department in which the animal was bred), and gathering centre (French department in which the animal was grouped with the others before travelling to Italy). The following parasites were identified: Eimeriidae (overall prevalence 60.5%); Strongyles (59%); Nematodirus spp. (14.3%); Trichuris spp. (4.1%); Capillaria spp. (2.0%); Paramphistomum spp. (27.6%); Dicrocoelium spp. (3.0%); Moniezia spp. (8.7%). All the observed parasites are widely reported in beef cattle either in Italy or in France. However, the seeming absence of Fasciola hepatica was unexpected, as well as the high prevalence of Paramphistomum spp. The variables that appeared to be more linked to parasite epidemiology were sex, altitude of the geographical origin and season.

Low flows and reservoir management for the Durance River basin (Southern France) in the 2050s

NASA Astrophysics Data System (ADS)

Sauquet, Eric

2015-04-01

. A model of water management similar to the tools used by Electricité De France was calibrated to simulate the behavior of the three reservoirs Serre-Ponçon, Castillon, Sainte-Croix on present-day conditions. This model simulates water releases from reservoir under constraints imposed by rule curves, ecological flows downstream to the dams and water levels in summer for recreational purposes. The results demonstrate the relatively good performance of this simplified model and its ability to represent the influence of reservoir operations on the natural hydrological river flow regime, the decision-making involved in water management and the interactions at regional scale. Four territorial socio-economic scenarios have been also elaborated with the help of stake holders to project water needs in the 2050s for the area supplied with water from the Durance River basin. This presentation will focus on the specific tools developed within the project to simulate water management and water abstractions. The main conclusions related to the risk of water shortage in the 2050s and the level of satisfaction for each water use will be also discussed.

75 FR 39277 - Sorbitol From France; Determination

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-08

... INTERNATIONAL TRADE COMMISSION [Investigation No. 731-TA-44 (Third Review)] Sorbitol From France... U.S.C. 1675d(c)) (the Act), that revocation of the antidumping duty order on sorbitol from France... views of the Commission are contained in USITC Publication 4164 (June 2010), entitled Sorbitol from...

Mapping environmental susceptibility to Saint Louis encephalitis virus, based on a decision tree model of remotely-sensed data.

PubMed

Rotela, Camilo H; Spinsanti, Lorena I; Lamfri, Mario A; Contigiani, Marta S; Almirón, Walter R; Scavuzzo, Carlos M

2011-11-01

In response to the first human outbreak (January May 2005) of Saint Louis encephalitis (SLE) virus in Córdoba province, Argentina, we developed an environmental SLE virus risk map for the capital, i.e. Córdoba city. The aim was to provide a map capable of detecting macro-environmental factors associated with the spatial distribution of SLE cases, based on remotely sensed data and a geographical information system. Vegetation, soil brightness, humidity status, distances to water-bodies and areas covered by vegetation were assessed based on pre-outbreak images provided by the Landsat 5TM satellite. A strong inverse relationship between the number of humans infected by SLEV and distance to high-vigor vegetation was noted. A statistical non-hierarchic decision tree model was constructed, based on environmental variables representing the areas surrounding patient residences. From this point of view, 18% of the city could be classified as being at high risk for SLEV infection, while 34% carried a low risk, or none at all. Taking the whole 2005 epidemic into account, 80% of the cases came from areas classified by the model as medium-high or high risk. Almost 46% of the cases were registered in high-risk areas, while there were no cases (0%) in areas affirmed as risk free.

Synchrotron-based far-infrared spectroscopy of furan: Rotational analysis of the ν 14 , ν 11 , ν 18 and ν 19 vibrational levels

NASA Astrophysics Data System (ADS)

Tokaryk, D. W.; Culligan, S. D.; Billinghurst, B. E.; van Wijngaarden, J. A.

2011-11-01

Four vibrational levels of the five-membered ring molecule furan (C 4H 4O) have been rotationally analyzed from far-infrared Fourier transform spectra obtained at the Canadian Light Source synchrotron. We found that the low-lying ν14 and ν11 levels at 602.9 and 599.6 cm -1 interact through a second-order Coriolis resonance. This perturbation was characterized through a coupled analysis of the ν14 and ν18 fundamental spectra and the ν18- ν11 band. The ν19 fundamental spectrum was analyzed as well, and the data for all observed bands were combined with previously reported microwave transitions to produce the final fit. The spectra are an excellent demonstration of the high quality of data that can be obtained when far-infrared synchrotron radiation is used as the radiation source in Fourier transform spectroscopy experiments.

Selected Rapporteur Summaries from the XX World Congress of Psychiatric Genetics, Hamburg, Germany, October 14-18, 2012

PubMed Central

Anderson-Schmidt, Heike; Beltcheva, Olga; Brandon, Mariko D; Byrne, Enda M; Diehl, Eric J; Duncan, Laramie; Gonzalez, Suzanne D; Hannon, Eilis; Kantojärvi, Katri; Karagiannidis, Iordanis; Kos, Mark Z; Kotyuk, Eszter; Laufer, Benjamin I; Mantha, Katarzyna; McGregor, Nathaniel W; Meier, Sandra; Nieratschker, Vanessa; Spiers, Helen; Squassina, Alessio; Thakur, Geeta A; Tiwari, Yash; Viswanath, Biju; Way, Michael J; Wong, Cybele CP; O'Shea, Anne; DeLisi, Lynn E

2014-01-01

The XXth World Congress of Psychiatric Genetics (WCPG), sponsored by The International Society of Psychiatric Genetics (ISPG) took place in Hamburg, Germany on October 14-18, 2012. Approximately 600 participants gathered to discuss the latest findings in this rapidly advancing field. The following report was written by student travel awardees. Each was assigned sessions as rapporteurs. This manuscript represents topics covered in most, but not all, oral presentations during the conference, and some of the major notable new findings reported at this 2012 WCPG. PMID:23341144

A Collaborative Approach to Monitoring Ambient Volcanogenic Pollution at Sulphur Springs, Saint Lucia.

NASA Astrophysics Data System (ADS)

Joseph, E. P.; Beckles, D. M.; Cox, L.; Jackson, V. B.; Alexander, D.

2015-12-01

The role of volcano tourism is recognized as an important contributor to the economy of volcanic islands in the Lesser Antilles. However, if it is to be promoted as a sustainable sector of the tourism industry, visitors, tour operators, and vendors must be made aware of the potential health hazards facing them in volcanic environments. Volcanogenic air pollutants are of primary concern in this setting. In general, no warning signs, guidelines for recreational use, or emissions monitoring currently exists to provide warning to the public to decrease their vulnerability to the potential risks, or to minimize the liability of the agencies managing these areas. Sulphur Springs Park in Saint Lucia is a popular international destination, and concerns about the volcanic emissions and its possible health effect have been raised by visitors, staff, and management of the Park. As part of the responsibility of the UWI, Seismic Research Centre (SRC) to provide volcanic surveillance through its geothermal monitoring programme, a network was established for quantifying the ambient SO2 concentrations at Sulphur Springs in order to assess the potential risk of unsafe exposure. This effort required collaboration with the National Emergency Management Organization (NEMO) of Saint Lucia, as well as the staff and management of the Soufrière Regional Development Foundation (SRDF). Local personnel were trained in the active field sampling and analytical techniques required for the assessment of ambient SO2 concentrations over the monitoring period, thereby contributing to an active community-based effort. This type of approach was also thought to be an effective option for scientists to engage communities as partners in disaster risk reduction. Lessons learnt from this experience are presented for the benefit of other citizen monitoring projects, including its use as a tool for promoting volcanic hazard education, and enhancing communication and understanding between geoscientists and

Uranium mining in France

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, L.

Since the onset of the first ''oil shock'' in 1974, France has pursued a policy of steadily increasing energy independence based on nuclear power for generation of electricity. In 1973, nuclear reactors supplied only 8% of France's electrical power. A strong development effort lifted the nuclear share to 23% in 1980, to 66% in 1985, and the plan is to raise the total to 75% by 1990. In 1976, Cogema (Compagnie Generale des Matieres Nucleaires) was organized from the production division of France's Commissariat a l'Energie Atomique (CEA) to handle fuel supply and spent fuel reprocessing for the expanding industrymore » (see subsequent article on Cogema). In parallel with growth of the French nuclear power, Cogema has become a world leader in all aspects of the fuel cycle, providing services not only domestically but internationally as well. As a uranium mining company, Cogema has steadily developed domestic and foreign sources of supply, and over the years it has maintained the world's strongest uranium exploration effort throughout the ups and downs of the market. As a result, the company has become the world's leading uranium supplier, with about 20% of total production contributed either by its domestic mining divisions or overseas subsidiaries.« less

Levels of insecticide resistance to deltamethrin, malathion, and temephos, and associated mechanisms in Aedes aegypti mosquitoes from the Guadeloupe and Saint Martin islands (French West Indies).

PubMed

Goindin, Daniella; Delannay, Christelle; Gelasse, Andric; Ramdini, Cédric; Gaude, Thierry; Faucon, Frédéric; David, Jean-Philippe; Gustave, Joël; Vega-Rua, Anubis; Fouque, Florence

2017-02-10

In the Guadeloupe and Saint Martin islands, Aedes aegypti mosquitoes are the only recognized vectors of dengue, chikungunya, and Zika viruses. For around 40 years, malathion was used as a mosquito adulticide and temephos as a larvicide. Since the European Union banned the use of these two insecticide molecules in the first decade of the 21st century, deltamethrin and Bacillus thuringiensis var. israelensis are the remaining adulticide and larvicide, respectively, used in Guadeloupe. In order to improve the management of vector control activities in Guadeloupe and Saint Martin, we investigated Ae. aegypti resistance to and mechanisms associated with deltamethrin, malathion, and temephos. Ae. aegypti mosquitoes were collected from six different localities of Guadeloupe and Saint Martin. Larvae were used for malathion and temephos bioassays, and adult mosquitoes for deltamethrin bioassays, following World Health Organization recommendations. Knockdown resistance (Kdr) genotyping for V1016I and F1534C mutations, and expression levels of eight enzymes involved in detoxification mechanisms were examined in comparison with the susceptible reference Bora Bora strain. Resistance ratios (RR 50 ) calculated for Ae. aegypti larvae showed high resistance levels to temephos (from 8.9 to 33.1-fold) and low resistance levels to malathion (from 1.7 to 4.4-fold). Adult females displayed moderate resistance levels to deltamethrin regarding the time necessary to affect 50% of individuals, varying from 8.0 to 28.1-fold. Molecular investigations on adult mosquitoes showed high resistant allele frequencies for V1016I and F1534C (from 85 to 96% and from 90 to 98%, respectively), as well as an overexpression of the glutathione S-transferase gene, GSTe2, the carboxylesterase CCEae3a, and the cytochrome genes 014614, CYP6BB2, CYP6M11, and CYP9J23. Ae. aegypti populations from Guadeloupe and Saint Martin exhibit multiple resistance to organophosphates (temephos and malathion), and

Diversity of Group I and II Clostridium botulinum Strains from France Including Recently Identified Subtypes.

PubMed

Mazuet, Christelle; Legeay, Christine; Sautereau, Jean; Ma, Laurence; Bouchier, Christiane; Bouvet, Philippe; Popoff, Michel R

2016-06-13

In France, human botulism is mainly food-borne intoxication, whereas infant botulism is rare. A total of 99 group I and II Clostridium botulinum strains including 59 type A (12 historical isolates [1947-1961], 43 from France [1986-2013], 3 from other countries, and 1 collection strain), 31 type B (3 historical, 23 recent isolates, 4 from other countries, and 1 collection strain), and 9 type E (5 historical, 3 isolates, and 1 collection strain) were investigated by botulinum locus gene sequencing and multilocus sequence typing analysis. Historical C. botulinum A strains mainly belonged to subtype A1 and sequence type (ST) 1, whereas recent strains exhibited a wide genetic diversity: subtype A1 in orfX or ha locus, A1(B), A1(F), A2, A2b2, A5(B2') A5(B3'), as well as the recently identified A7 and A8 subtypes, and were distributed into 25 STs. Clostridium botulinum A1(B) was the most frequent subtype from food-borne botulism and food. Group I C. botulinum type B in France were mainly subtype B2 (14 out of 20 historical and recent strains) and were divided into 19 STs. Food-borne botulism resulting from ham consumption during the recent period was due to group II C. botulinum B4. Type E botulism is rare in France, 5 historical and 1 recent strains were subtype E3. A subtype E12 was recently identified from an unusual ham contamination. Clostridium botulinum strains from human botulism in France showed a wide genetic diversity and seems to result not from a single evolutionary lineage but from multiple and independent genetic rearrangements. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.