A Differential Monolithically Integrated Inductive Linear Displacement Measurement Microsystem.

PubMed

Podhraški, Matija; Trontelj, Janez

2016-03-17

An inductive linear displacement measurement microsystem realized as a monolithic Application-Specific Integrated Circuit (ASIC) is presented. The system comprises integrated microtransformers as sensing elements, and analog front-end electronics for signal processing and demodulation, both jointly fabricated in a conventional commercially available four-metal 350-nm CMOS process. The key novelty of the presented system is its full integration, straightforward fabrication, and ease of application, requiring no external light or magnetic field source. Such systems therefore have the possibility of substituting certain conventional position encoder types. The microtransformers are excited by an AC signal in MHz range. The displacement information is modulated into the AC signal by a metal grating scale placed over the microsystem, employing a differential measurement principle. Homodyne mixing is used for the demodulation of the scale displacement information, returned by the ASIC as a DC signal in two quadrature channels allowing the determination of linear position of the target scale. The microsystem design, simulations, and characterization are presented. Various system operating conditions such as frequency, phase, target scale material and distance have been experimentally evaluated. The best results have been achieved at 4 MHz, demonstrating a linear resolution of 20 µm with steel and copper scale, having respective sensitivities of 0.71 V/mm and 0.99 V/mm.

Energy Systems Integration Facility Overview

ScienceCinema

Arvizu, Dan; Chistensen, Dana; Hannegan, Bryan; Garret, Bobi; Kroposki, Ben; Symko-Davies, Martha; Post, David; Hammond, Steve; Kutscher, Chuck; Wipke, Keith

2018-01-16

The U.S. Department of Energy's Energy Systems Integration Facility (ESIF) is located at the National Renewable Energy Laboratory is the right tool, at the right time... a first-of-its-kind facility that addresses the challenges of large-scale integration of clean energy technologies into the energy systems that power the nation.

Scale relativity theory and integrative systems biology: 1. Founding principles and scale laws.

PubMed

Auffray, Charles; Nottale, Laurent

2008-05-01

In these two companion papers, we provide an overview and a brief history of the multiple roots, current developments and recent advances of integrative systems biology and identify multiscale integration as its grand challenge. Then we introduce the fundamental principles and the successive steps that have been followed in the construction of the scale relativity theory, and discuss how scale laws of increasing complexity can be used to model and understand the behaviour of complex biological systems. In scale relativity theory, the geometry of space is considered to be continuous but non-differentiable, therefore fractal (i.e., explicitly scale-dependent). One writes the equations of motion in such a space as geodesics equations, under the constraint of the principle of relativity of all scales in nature. To this purpose, covariant derivatives are constructed that implement the various effects of the non-differentiable and fractal geometry. In this first review paper, the scale laws that describe the new dependence on resolutions of physical quantities are obtained as solutions of differential equations acting in the scale space. This leads to several possible levels of description for these laws, from the simplest scale invariant laws to generalized laws with variable fractal dimensions. Initial applications of these laws to the study of species evolution, embryogenesis and cell confinement are discussed.

The Emergence of Dominant Design(s) in Large Scale Cyber-Infrastructure Systems

ERIC Educational Resources Information Center

Diamanti, Eirini Ilana

2012-01-01

Cyber-infrastructure systems are integrated large-scale IT systems designed with the goal of transforming scientific practice by enabling multi-disciplinary, cross-institutional collaboration. Their large scale and socio-technical complexity make design decisions for their underlying architecture practically irreversible. Drawing on three…

Integrated fringe projection 3D scanning system for large-scale metrology based on laser tracker

NASA Astrophysics Data System (ADS)

Du, Hui; Chen, Xiaobo; Zhou, Dan; Guo, Gen; Xi, Juntong

2017-10-01

Large scale components exist widely in advance manufacturing industry,3D profilometry plays a pivotal role for the quality control. This paper proposes a flexible, robust large-scale 3D scanning system by integrating a robot with a binocular structured light scanner and a laser tracker. The measurement principle and system construction of the integrated system are introduced. And a mathematical model is established for the global data fusion. Subsequently, a flexible and robust method and mechanism is introduced for the establishment of the end coordination system. Based on this method, a virtual robot noumenon is constructed for hand-eye calibration. And then the transformation matrix between end coordination system and world coordination system is solved. Validation experiment is implemented for verifying the proposed algorithms. Firstly, hand-eye transformation matrix is solved. Then a car body rear is measured for 16 times for the global data fusion algorithm verification. And the 3D shape of the rear is reconstructed successfully.

Dan Says - Continuum Magazine | NREL

Science.gov Websites

Dan Says Leading Energy Systems Integration A headshot of a man in a suit, smiling. Photo by Dennis U.S. dedicated to solving the complex problems associated with energy systems integration (ESI) on a national scale. Our 185,000-square-foot Energy Systems Integration Facility (ESIF) is designed to provide a

Integrative Systems Models of Cardiac Excitation Contraction Coupling

PubMed Central

Greenstein, Joseph L.; Winslow, Raimond L.

2010-01-01

Excitation-contraction coupling in the cardiac myocyte is mediated by a number of highly integrated mechanisms of intracellular Ca2+ transport. The complexity and integrative nature of heart cell electrophysiology and Ca2+-cycling has led to an evolution of computational models that have played a crucial role in shaping our understanding of heart function. An important emerging theme in systems biology is that the detailed nature of local signaling events, such as those that occur in the cardiac dyad, have important consequences at higher biological scales. Multi-scale modeling techniques have revealed many mechanistic links between micro-scale events, such as Ca2+ binding to a channel protein, and macro-scale phenomena, such as excitation-contraction coupling gain. Here we review experimentally based multi-scale computational models of excitation-contraction coupling and the insights that have been gained through their application. PMID:21212390

Single-chip microprocessor that communicates directly using light.

PubMed

Sun, Chen; Wade, Mark T; Lee, Yunsup; Orcutt, Jason S; Alloatti, Luca; Georgas, Michael S; Waterman, Andrew S; Shainline, Jeffrey M; Avizienis, Rimas R; Lin, Sen; Moss, Benjamin R; Kumar, Rajesh; Pavanello, Fabio; Atabaki, Amir H; Cook, Henry M; Ou, Albert J; Leu, Jonathan C; Chen, Yu-Hsin; Asanović, Krste; Ram, Rajeev J; Popović, Miloš A; Stojanović, Vladimir M

2015-12-24

Data transport across short electrical wires is limited by both bandwidth and power density, which creates a performance bottleneck for semiconductor microchips in modern computer systems--from mobile phones to large-scale data centres. These limitations can be overcome by using optical communications based on chip-scale electronic-photonic systems enabled by silicon-based nanophotonic devices. However, combining electronics and photonics on the same chip has proved challenging, owing to microchip manufacturing conflicts between electronics and photonics. Consequently, current electronic-photonic chips are limited to niche manufacturing processes and include only a few optical devices alongside simple circuits. Here we report an electronic-photonic system on a single chip integrating over 70 million transistors and 850 photonic components that work together to provide logic, memory, and interconnect functions. This system is a realization of a microprocessor that uses on-chip photonic devices to directly communicate with other chips using light. To integrate electronics and photonics at the scale of a microprocessor chip, we adopt a 'zero-change' approach to the integration of photonics. Instead of developing a custom process to enable the fabrication of photonics, which would complicate or eliminate the possibility of integration with state-of-the-art transistors at large scale and at high yield, we design optical devices using a standard microelectronics foundry process that is used for modern microprocessors. This demonstration could represent the beginning of an era of chip-scale electronic-photonic systems with the potential to transform computing system architectures, enabling more powerful computers, from network infrastructure to data centres and supercomputers.

Integrating national community-based health worker programmes into health systems: a systematic review identifying lessons learned from low-and middle-income countries.

PubMed

Zulu, Joseph Mumba; Kinsman, John; Michelo, Charles; Hurtig, Anna-Karin

2014-09-22

Despite the development of national community-based health worker (CBHW) programmes in several low- and middle-income countries, their integration into health systems has not been optimal. Studies have been conducted to investigate the factors influencing the integration processes, but systematic reviews to provide a more comprehensive understanding are lacking. We conducted a systematic review of published research to understand factors that may influence the integration of national CBHW programmes into health systems in low- and middle-income countries. To be included in the study, CBHW programmes should have been developed by the government and have standardised training, supervision and incentive structures. A conceptual framework on the integration of health innovations into health systems guided the review. We identified 3410 records, of which 36 were finally selected, and on which an analysis was conducted concerning the themes and pathways associated with different factors that may influence the integration process. Four programmes from Brazil, Ethiopia, India and Pakistan met the inclusion criteria. Different aspects of each of these programmes were integrated in different ways into their respective health systems. Factors that facilitated the integration process included the magnitude of countries' human resources for health problems and the associated discourses about how to address these problems; the perceived relative advantage of national CBHWs with regard to delivering health services over training and retaining highly skilled health workers; and the participation of some politicians and community members in programme processes, with the result that they viewed the programmes as legitimate, credible and relevant. Finally, integration of programmes within the existing health systems enhanced programme compatibility with the health systems' governance, financing and training functions. Factors that inhibited the integration process included a rapid scale-up process; resistance from other health workers; discrimination of CBHWs based on social, gender and economic status; ineffective incentive structures; inadequate infrastructure and supplies; and hierarchical and parallel communication structures. CBHW programmes should design their scale-up strategy differently based on current contextual factors. Further, adoption of a stepwise approach to the scale-up and integration process may positively shape the integration process of CBHW programmes into health systems.

Spin diffusion from an inhomogeneous quench in an integrable system.

PubMed

Ljubotina, Marko; Žnidarič, Marko; Prosen, Tomaž

2017-07-13

Generalized hydrodynamics predicts universal ballistic transport in integrable lattice systems when prepared in generic inhomogeneous initial states. However, the ballistic contribution to transport can vanish in systems with additional discrete symmetries. Here we perform large scale numerical simulations of spin dynamics in the anisotropic Heisenberg XXZ spin 1/2 chain starting from an inhomogeneous mixed initial state which is symmetric with respect to a combination of spin reversal and spatial reflection. In the isotropic and easy-axis regimes we find non-ballistic spin transport which we analyse in detail in terms of scaling exponents of the transported magnetization and scaling profiles of the spin density. While in the easy-axis regime we find accurate evidence of normal diffusion, the spin transport in the isotropic case is clearly super-diffusive, with the scaling exponent very close to 2/3, but with universal scaling dynamics which obeys the diffusion equation in nonlinearly scaled time.

Investigating the Nexus of Climate, Energy, Water, and Land at Decision-Relevant Scales: The Platform for Regional Integrated Modeling and Analysis (PRIMA)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kraucunas, Ian P.; Clarke, Leon E.; Dirks, James A.

2015-04-01

The Platform for Regional Integrated Modeling and Analysis (PRIMA) is an innovative modeling system developed at Pacific Northwest National Laboratory (PNNL) to simulate interactions among natural and human systems at scales relevant to regional decision making. PRIMA brings together state-of-the-art models of regional climate, hydrology, agriculture, socioeconomics, and energy systems using a flexible coupling approach. The platform can be customized to inform a variety of complex questions and decisions, such as the integrated evaluation of mitigation and adaptation options across a range of sectors. Research into stakeholder decision support needs underpins the platform's application to regional issues, including uncertainty characterization.more » Ongoing numerical experiments are yielding new insights into the interactions among human and natural systems on regional scales with an initial focus on the energy-land-water nexus in the upper U.S. Midwest. This paper focuses on PRIMA’s functional capabilities and describes some lessons learned to date about integrated regional modeling.« less

System-Integrated Finite Element Analysis of a Full-Scale Helicopter Crash Test with Deployable Energy Absorbers

NASA Technical Reports Server (NTRS)

Annett, Martin S.; Polanco, Michael A.

2010-01-01

A full-scale crash test of an MD-500 helicopter was conducted in December 2009 at NASA Langley's Landing and Impact Research facility (LandIR). The MD-500 helicopter was fitted with a composite honeycomb Deployable Energy Absorber (DEA) and tested under vertical and horizontal impact velocities of 26-ft/sec and 40-ft/sec, respectively. The objectives of the test were to evaluate the performance of the DEA concept under realistic crash conditions and to generate test data for validation of a system integrated finite element model. In preparation for the full-scale crash test, a series of sub-scale and MD-500 mass simulator tests was conducted to evaluate the impact performances of various components, including a new crush tube and the DEA blocks. Parameters defined within the system integrated finite element model were determined from these tests. The objective of this paper is to summarize the finite element models developed and analyses performed, beginning with pre-test predictions and continuing through post-test validation.

Development of a survey instrument to measure patient experience of integrated care.

PubMed

Walker, Kara Odom; Stewart, Anita L; Grumbach, Kevin

2016-06-01

Healthcare systems are working to move towards more integrated, patient-centered care. This study describes the development and testing of a multidimensional self-report measure of patients' experiences of integrated care. Random-digit-dial telephone survey in 2012 of 317 adults aged 40 years or older in the San Francisco region who had used healthcare at least twice in the past 12 months. One-time cross-sectional survey; psychometric evaluation to confirm dimensions and create multi-item scales. Survey data were analyzed using VARCLUS and confirmatory factor analysis and internal consistency reliability testing. Scales measuring five domains were confirmed: coordination within and between care teams, navigation (arranging appointments and visits), communication between specialist and primary care doctor, and communication between primary care doctor and specialist. Four of these demonstrated excellent internal consistency reliability. Mean scale scores indicated low levels of integration. These scales measuring integrated care capture meaningful domains of patients' experiences of health care. The low levels of care integration reported by patients in the study sample suggest that these types of measures should be considered in ongoing evaluations of health system performance and improvement. Further research should examine whether differences in patient experience of integrated care are associated with differences in the processes and outcomes of care received.

Experiences Integrating Transmission and Distribution Simulations for DERs with the Integrated Grid Modeling System (IGMS)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Palmintier, Bryan; Hale, Elaine; Hodge, Bri-Mathias

2016-08-11

This paper discusses the development of, approaches for, experiences with, and some results from a large-scale, high-performance-computer-based (HPC-based) co-simulation of electric power transmission and distribution systems using the Integrated Grid Modeling System (IGMS). IGMS was developed at the National Renewable Energy Laboratory (NREL) as a novel Independent System Operator (ISO)-to-appliance scale electric power system modeling platform that combines off-the-shelf tools to simultaneously model 100s to 1000s of distribution systems in co-simulation with detailed ISO markets, transmission power flows, and AGC-level reserve deployment. Lessons learned from the co-simulation architecture development are shared, along with a case study that explores the reactivemore » power impacts of PV inverter voltage support on the bulk power system.« less

Adaptive Fault-Tolerant Control of Uncertain Nonlinear Large-Scale Systems With Unknown Dead Zone.

PubMed

Chen, Mou; Tao, Gang

2016-08-01

In this paper, an adaptive neural fault-tolerant control scheme is proposed and analyzed for a class of uncertain nonlinear large-scale systems with unknown dead zone and external disturbances. To tackle the unknown nonlinear interaction functions in the large-scale system, the radial basis function neural network (RBFNN) is employed to approximate them. To further handle the unknown approximation errors and the effects of the unknown dead zone and external disturbances, integrated as the compounded disturbances, the corresponding disturbance observers are developed for their estimations. Based on the outputs of the RBFNN and the disturbance observer, the adaptive neural fault-tolerant control scheme is designed for uncertain nonlinear large-scale systems by using a decentralized backstepping technique. The closed-loop stability of the adaptive control system is rigorously proved via Lyapunov analysis and the satisfactory tracking performance is achieved under the integrated effects of unknown dead zone, actuator fault, and unknown external disturbances. Simulation results of a mass-spring-damper system are given to illustrate the effectiveness of the proposed adaptive neural fault-tolerant control scheme for uncertain nonlinear large-scale systems.

A large scale software system for simulation and design optimization of mechanical systems

NASA Technical Reports Server (NTRS)

Dopker, Bernhard; Haug, Edward J.

1989-01-01

The concept of an advanced integrated, networked simulation and design system is outlined. Such an advanced system can be developed utilizing existing codes without compromising the integrity and functionality of the system. An example has been used to demonstrate the applicability of the concept of the integrated system outlined here. The development of an integrated system can be done incrementally. Initial capabilities can be developed and implemented without having a detailed design of the global system. Only a conceptual global system must exist. For a fully integrated, user friendly design system, further research is needed in the areas of engineering data bases, distributed data bases, and advanced user interface design.

Hierarchical modeling and robust synthesis for the preliminary design of large scale complex systems

NASA Astrophysics Data System (ADS)

Koch, Patrick Nathan

Large-scale complex systems are characterized by multiple interacting subsystems and the analysis of multiple disciplines. The design and development of such systems inevitably requires the resolution of multiple conflicting objectives. The size of complex systems, however, prohibits the development of comprehensive system models, and thus these systems must be partitioned into their constituent parts. Because simultaneous solution of individual subsystem models is often not manageable iteration is inevitable and often excessive. In this dissertation these issues are addressed through the development of a method for hierarchical robust preliminary design exploration to facilitate concurrent system and subsystem design exploration, for the concurrent generation of robust system and subsystem specifications for the preliminary design of multi-level, multi-objective, large-scale complex systems. This method is developed through the integration and expansion of current design techniques: (1) Hierarchical partitioning and modeling techniques for partitioning large-scale complex systems into more tractable parts, and allowing integration of subproblems for system synthesis, (2) Statistical experimentation and approximation techniques for increasing both the efficiency and the comprehensiveness of preliminary design exploration, and (3) Noise modeling techniques for implementing robust preliminary design when approximate models are employed. The method developed and associated approaches are illustrated through their application to the preliminary design of a commercial turbofan turbine propulsion system; the turbofan system-level problem is partitioned into engine cycle and configuration design and a compressor module is integrated for more detailed subsystem-level design exploration, improving system evaluation.

Integration and validation testing for PhEDEx, DBS and DAS with the PhEDEx LifeCycle agent

NASA Astrophysics Data System (ADS)

Boeser, C.; Chwalek, T.; Giffels, M.; Kuznetsov, V.; Wildish, T.

2014-06-01

The ever-increasing amount of data handled by the CMS dataflow and workflow management tools poses new challenges for cross-validation among different systems within CMS experiment at LHC. To approach this problem we developed an integration test suite based on the LifeCycle agent, a tool originally conceived for stress-testing new releases of PhEDEx, the CMS data-placement tool. The LifeCycle agent provides a framework for customising the test workflow in arbitrary ways, and can scale to levels of activity well beyond those seen in normal running. This means we can run realistic performance tests at scales not likely to be seen by the experiment for some years, or with custom topologies to examine particular situations that may cause concern some time in the future. The LifeCycle agent has recently been enhanced to become a general purpose integration and validation testing tool for major CMS services. It allows cross-system integration tests of all three components to be performed in controlled environments, without interfering with production services. In this paper we discuss the design and implementation of the LifeCycle agent. We describe how it is used for small-scale debugging and validation tests, and how we extend that to large-scale tests of whole groups of sub-systems. We show how the LifeCycle agent can emulate the action of operators, physicists, or software agents external to the system under test, and how it can be scaled to large and complex systems.

Single-chip microprocessor that communicates directly using light

NASA Astrophysics Data System (ADS)

Sun, Chen; Wade, Mark T.; Lee, Yunsup; Orcutt, Jason S.; Alloatti, Luca; Georgas, Michael S.; Waterman, Andrew S.; Shainline, Jeffrey M.; Avizienis, Rimas R.; Lin, Sen; Moss, Benjamin R.; Kumar, Rajesh; Pavanello, Fabio; Atabaki, Amir H.; Cook, Henry M.; Ou, Albert J.; Leu, Jonathan C.; Chen, Yu-Hsin; Asanović, Krste; Ram, Rajeev J.; Popović, Miloš A.; Stojanović, Vladimir M.

2015-12-01

Data transport across short electrical wires is limited by both bandwidth and power density, which creates a performance bottleneck for semiconductor microchips in modern computer systems—from mobile phones to large-scale data centres. These limitations can be overcome by using optical communications based on chip-scale electronic-photonic systems enabled by silicon-based nanophotonic devices8. However, combining electronics and photonics on the same chip has proved challenging, owing to microchip manufacturing conflicts between electronics and photonics. Consequently, current electronic-photonic chips are limited to niche manufacturing processes and include only a few optical devices alongside simple circuits. Here we report an electronic-photonic system on a single chip integrating over 70 million transistors and 850 photonic components that work together to provide logic, memory, and interconnect functions. This system is a realization of a microprocessor that uses on-chip photonic devices to directly communicate with other chips using light. To integrate electronics and photonics at the scale of a microprocessor chip, we adopt a ‘zero-change’ approach to the integration of photonics. Instead of developing a custom process to enable the fabrication of photonics, which would complicate or eliminate the possibility of integration with state-of-the-art transistors at large scale and at high yield, we design optical devices using a standard microelectronics foundry process that is used for modern microprocessors. This demonstration could represent the beginning of an era of chip-scale electronic-photonic systems with the potential to transform computing system architectures, enabling more powerful computers, from network infrastructure to data centres and supercomputers.

The Integrative Psychotherapy Alliance: Family, Couple and Individual Therapy Scales.

ERIC Educational Resources Information Center

Pinsof, William M.; Catherall, Donald R.

1986-01-01

Presents an integrative definition of the therapeutic alliance that conceptualizes individual, couple and family therapy as occurring within the same systemic framework. The implications of this concept for therapy reserach are examined. Three new systematically oriented scales to measure the alliance are presented along with some preliminary data…

Integrated photoacoustic, ultrasound and fluorescence platform for diagnostic medical imaging-proof of concept study with a tissue mimicking phantom.

PubMed

James, Joseph; Murukeshan, Vadakke Matham; Woh, Lye Sun

2014-07-01

The structural and molecular heterogeneities of biological tissues demand the interrogation of the samples with multiple energy sources and provide visualization capabilities at varying spatial resolution and depth scales for obtaining complementary diagnostic information. A novel multi-modal imaging approach that uses optical and acoustic energies to perform photoacoustic, ultrasound and fluorescence imaging at multiple resolution scales from the tissue surface and depth is proposed in this paper. The system comprises of two distinct forms of hardware level integration so as to have an integrated imaging system under a single instrumentation set-up. The experimental studies show that the system is capable of mapping high resolution fluorescence signatures from the surface, optical absorption and acoustic heterogeneities along the depth (>2cm) of the tissue at multi-scale resolution (<1µm to <0.5mm).

Small scale adaptive optics experiment systems engineering

NASA Technical Reports Server (NTRS)

Boykin, William H.

1993-01-01

Assessment of the current technology relating to the laser power beaming system which in full scale is called the Beam Transmission Optical System (BTOS). Evaluation of system integration efforts are being conducted by the various government agencies and industry. Concepts are being developed for prototypes of adaptive optics for a BTOS.

Root Systems Biology: Integrative Modeling across Scales, from Gene Regulatory Networks to the Rhizosphere1

PubMed Central

Hill, Kristine; Porco, Silvana; Lobet, Guillaume; Zappala, Susan; Mooney, Sacha; Draye, Xavier; Bennett, Malcolm J.

2013-01-01

Genetic and genomic approaches in model organisms have advanced our understanding of root biology over the last decade. Recently, however, systems biology and modeling have emerged as important approaches, as our understanding of root regulatory pathways has become more complex and interpreting pathway outputs has become less intuitive. To relate root genotype to phenotype, we must move beyond the examination of interactions at the genetic network scale and employ multiscale modeling approaches to predict emergent properties at the tissue, organ, organism, and rhizosphere scales. Understanding the underlying biological mechanisms and the complex interplay between systems at these different scales requires an integrative approach. Here, we describe examples of such approaches and discuss the merits of developing models to span multiple scales, from network to population levels, and to address dynamic interactions between plants and their environment. PMID:24143806

Systems Proteomics for Translational Network Medicine

PubMed Central

Arrell, D. Kent; Terzic, Andre

2012-01-01

Universal principles underlying network science, and their ever-increasing applications in biomedicine, underscore the unprecedented capacity of systems biology based strategies to synthesize and resolve massive high throughput generated datasets. Enabling previously unattainable comprehension of biological complexity, systems approaches have accelerated progress in elucidating disease prediction, progression, and outcome. Applied to the spectrum of states spanning health and disease, network proteomics establishes a collation, integration, and prioritization algorithm to guide mapping and decoding of proteome landscapes from large-scale raw data. Providing unparalleled deconvolution of protein lists into global interactomes, integrative systems proteomics enables objective, multi-modal interpretation at molecular, pathway, and network scales, merging individual molecular components, their plurality of interactions, and functional contributions for systems comprehension. As such, network systems approaches are increasingly exploited for objective interpretation of cardiovascular proteomics studies. Here, we highlight network systems proteomic analysis pipelines for integration and biological interpretation through protein cartography, ontological categorization, pathway and functional enrichment and complex network analysis. PMID:22896016

Emerging concepts for management of river ecosystems and challenges to applied integration of physical and biological sciences in the Pacific Northwest, USA

Treesearch

Bruce E. Rieman; Jason B. Dunham; James L. Clayton

2006-01-01

Integration of biological and physical concepts is necessary to understand and conserve the ecological integrity of river systems. Past attempts at integration have often focused at relatively small scales and on mechanistic models that may not capture the complexity of natural systems leaving substantial uncertainty about ecological responses to management actions....

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trujillo, Angelina Michelle

Strategy, Planning, Acquiring- very large scale computing platforms come and go and planning for immensely scalable machines often precedes actual procurement by 3 years. Procurement can be another year or more. Integration- After Acquisition, machines must be integrated into the computing environments at LANL. Connection to scalable storage via large scale storage networking, assuring correct and secure operations. Management and Utilization – Ongoing operations, maintenance, and trouble shooting of the hardware and systems software at massive scale is required.

Scaling Analysis Techniques to Establish Experimental Infrastructure for Component, Subsystem, and Integrated System Testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sabharwall, Piyush; O'Brien, James E.; McKellar, Michael G.

2015-03-01

Hybrid energy system research has the potential to expand the application for nuclear reactor technology beyond electricity. The purpose of this research is to reduce both technical and economic risks associated with energy systems of the future. Nuclear hybrid energy systems (NHES) mitigate the variability of renewable energy sources, provide opportunities to produce revenue from different product streams, and avoid capital inefficiencies by matching electrical output to demand by using excess generation capacity for other purposes when it is available. An essential step in the commercialization and deployment of this advanced technology is scaled testing to demonstrate integrated dynamic performancemore » of advanced systems and components when risks cannot be mitigated adequately by analysis or simulation. Further testing in a prototypical environment is needed for validation and higher confidence. This research supports the development of advanced nuclear reactor technology and NHES, and their adaptation to commercial industrial applications that will potentially advance U.S. energy security, economy, and reliability and further reduce carbon emissions. Experimental infrastructure development for testing and feasibility studies of coupled systems can similarly support other projects having similar developmental needs and can generate data required for validation of models in thermal energy storage and transport, energy, and conversion process development. Experiments performed in the Systems Integration Laboratory will acquire performance data, identify scalability issues, and quantify technology gaps and needs for various hybrid or other energy systems. This report discusses detailed scaling (component and integrated system) and heat transfer figures of merit that will establish the experimental infrastructure for component, subsystem, and integrated system testing to advance the technology readiness of components and systems to the level required for commercial application and demonstration under NHES.« less

Scale invariance in natural and artificial collective systems: a review

PubMed Central

Huepe, Cristián

2017-01-01

Self-organized collective coordinated behaviour is an impressive phenomenon, observed in a variety of natural and artificial systems, in which coherent global structures or dynamics emerge from local interactions between individual parts. If the degree of collective integration of a system does not depend on size, its level of robustness and adaptivity is typically increased and we refer to it as scale-invariant. In this review, we first identify three main types of self-organized scale-invariant systems: scale-invariant spatial structures, scale-invariant topologies and scale-invariant dynamics. We then provide examples of scale invariance from different domains in science, describe their origins and main features and discuss potential challenges and approaches for designing and engineering artificial systems with scale-invariant properties. PMID:29093130

Large-scale flow experiments for managing river systems

USGS Publications Warehouse

Konrad, Christopher P.; Olden, Julian D.; Lytle, David A.; Melis, Theodore S.; Schmidt, John C.; Bray, Erin N.; Freeman, Mary C.; Gido, Keith B.; Hemphill, Nina P.; Kennard, Mark J.; McMullen, Laura E.; Mims, Meryl C.; Pyron, Mark; Robinson, Christopher T.; Williams, John G.

2011-01-01

Experimental manipulations of streamflow have been used globally in recent decades to mitigate the impacts of dam operations on river systems. Rivers are challenging subjects for experimentation, because they are open systems that cannot be isolated from their social context. We identify principles to address the challenges of conducting effective large-scale flow experiments. Flow experiments have both scientific and social value when they help to resolve specific questions about the ecological action of flow with a clear nexus to water policies and decisions. Water managers must integrate new information into operating policies for large-scale experiments to be effective. Modeling and monitoring can be integrated with experiments to analyze long-term ecological responses. Experimental design should include spatially extensive observations and well-defined, repeated treatments. Large-scale flow manipulations are only a part of dam operations that affect river systems. Scientists can ensure that experimental manipulations continue to be a valuable approach for the scientifically based management of river systems.

Emerging concepts for management of river ecosystems and challenges to applied integration of physical and biological sciences in the Pacific Northwest, USA

USGS Publications Warehouse

Rieman, Bruce; Dunham, Jason B.; Clayton, James

2006-01-01

Integration of biological and physical concepts is necessary to understand and conserve the ecological integrity of river systems. Past attempts at integration have often focused at relatively small scales and on mechanistic models that may not capture the complexity of natural systems leaving substantial uncertainty about ecological responses to management actions. Two solutions have been proposed to guide management in the face of that uncertainty: the use of “natural variability” in key environmental patterns, processes, or disturbance as a reference; and the retention of some areas as essentially unmanaged reserves to conserve and represent as much biological diversity as possible. Both concepts are scale dependent because dominant processes or patterns that might be referenced will change with scale. Context and linkages across scales may be as important in structuring biological systems as conditions within habitats used by individual organisms. Both ideas view the physical environment as a template for expression, maintenance, and evolution of ecological diversity. To conserve or restore a diverse physical template it will be important to recognize the ecologically important differences in physical characteristics and processes among streams or watersheds that we might attempt to mimic in management or represent in conservation or restoration reserves.

Emulsified systems based on glyceryl monostearate and potassium cetyl phosphate: scale-up and characterization of physical properties.

PubMed

Baby, André Rolim; Santoro, Diego Monegatto; Velasco, Maria Valéria Robles; Dos Reis Serra, Cristina Helena

2008-09-01

Introducing a pharmaceutical product on the market involves several stages of research. The scale-up stage comprises the integration of previous phases of development and their integration. This phase is extremely important since many process limitations which do not appear on the small scale become significant on the transposition to a large one. Since scientific literature presents only a few reports about the characterization of emulsified systems involving their scaling-up, this research work aimed at evaluating physical properties of non-ionic and anionic emulsions during their manufacturing phases: laboratory stage and scale-up. Prototype non-ionic (glyceryl monostearate) and anionic (potassium cetyl phosphate) emulsified systems had the physical properties by the determination of the droplet size (D[4,3], mum) and rheology profile. Transposition occurred from a batch of 500-50,000g. Semi-industrial manufacturing involved distinct conditions: intensity of agitation and homogenization. Comparing the non-ionic and anionic systems, it was observed that anionic emulsifiers generated systems with smaller droplet size and higher viscosity in laboratory scale. Besides that, for the concentrations tested, augmentation of the glyceryl monostearate emulsifier content provided formulations with better physical characteristics. For systems with potassium cetyl phosphate, droplet size increased with the elevation of the emulsifier concentration, suggesting inadequate stability. The scale-up provoked more significant alterations on the rheological profile and droplet size on the anionic systems than the non-ionic.

Optical correlator using very-large-scale integrated circuit/ferroelectric-liquid-crystal electrically addressed spatial light modulators

NASA Technical Reports Server (NTRS)

Turner, Richard M.; Jared, David A.; Sharp, Gary D.; Johnson, Kristina M.

1993-01-01

The use of 2-kHz 64 x 64 very-large-scale integrated circuit/ferroelectric-liquid-crystal electrically addressed spatial light modulators as the input and filter planes of a VanderLugt-type optical correlator is discussed. Liquid-crystal layer thickness variations that are present in the devices are analyzed, and the effects on correlator performance are investigated through computer simulations. Experimental results from the very-large-scale-integrated / ferroelectric-liquid-crystal optical-correlator system are presented and are consistent with the level of performance predicted by the simulations.

Quantifying Impacts of Land-use and Land Cover Change in a Changing Climate at the Regional Scale using an Integrated Earth System Modeling Approach

NASA Astrophysics Data System (ADS)

Huang, M.

2016-12-01

Earth System models (ESMs) are effective tools for investigating the water-energy-food system interactions under climate change. In this presentation, I will introduce research efforts at the Pacific Northwest National Laboratory towards quantifying impacts of LULCC on the water-energy-food nexus in a changing climate using an integrated regional Earth system modeling framework: the Platform for Regional Integrated Modeling and Analysis (PRIMA). Two studies will be discussed to showcase the capability of PRIMA: (1) quantifying changes in terrestrial hydrology over the Conterminous US (CONUS) from 2005 to 2095 using the Community Land Model (CLM) driven by high-resolution downscaled climate and land cover products from PRIMA, which was designed for assessing the impacts of and potential responses to climate and anthropogenic changes at regional scales; (2) applying CLM over the CONUS to provide the first county-scale model validation in simulating crop yields and assessing associated impacts on the water and energy budgets using CLM. The studies demonstrate the benefits of incorporating and coupling human activities into complex ESMs, and critical needs to account for the biogeophysical and biogeochemical effects of LULCC in climate impacts studies, and in designing mitigation and adaptation strategies at a scale meaningful for decision-making. Future directions in quantifying LULCC impacts on the water-energy-food nexus under a changing climate, as well as feedbacks among climate, energy production and consumption, and natural/managed ecosystems using an Integrated Multi-scale, Multi-sector Modeling framework will also be discussed.

Robust telerobotics - an integrated system for waste handling, characterization and sorting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Couture, S.A.; Hurd, R.L.; Wilhelmsen, K.C.

The Mixed Waste Management Facility (MWMF) at the Lawrence Livermore National Laboratory was designed to serve as a national testbed to demonstrate integrated technologies for the treatment of low-level organic mixed waste at a pilot-plant scale. Pilot-scale demonstration serves to bridge the gap between mature, bench-scale proven technologies and full-scale treatment facilities by providing the infrastructure needed to evaluate technologies in an integrated, front-end to back-end facility. Consistent with the intent to focus on technologies that are ready for pilot scale deployment, the front-end handling and feed preparation of incoming waste material has been designed to demonstrate the application ofmore » emerging robotic and remotely operated handling systems. The selection of telerobotics for remote handling in MWMF was made based on a number of factors - personnel protection, waste generation, maturity, cost, flexibility and extendibility. Telerobotics, or shared control of a manipulator by an operator and a computer, provides the flexibility needed to vary the amount of automation or operator intervention according to task complexity. As part of the telerobotics design effort, the technical risk of deploying the technology was reduced through focused developments and demonstrations. The work involved integrating key tools (1) to make a robust telerobotic system that operates at speeds and reliability levels acceptable to waste handling operators and, (2) to demonstrate an efficient operator interface that minimizes the amount of special training and skills needed by the operator. This paper describes the design and operation of the prototype telerobotic waste handling and sorting system that was developed for MWMF.« less

Technology and testing.

PubMed

Quellmalz, Edys S; Pellegrino, James W

2009-01-02

Large-scale testing of educational outcomes benefits already from technological applications that address logistics such as development, administration, and scoring of tests, as well as reporting of results. Innovative applications of technology also provide rich, authentic tasks that challenge the sorts of integrated knowledge, critical thinking, and problem solving seldom well addressed in paper-based tests. Such tasks can be used on both large-scale and classroom-based assessments. Balanced assessment systems can be developed that integrate curriculum-embedded, benchmark, and summative assessments across classroom, district, state, national, and international levels. We discuss here the potential of technology to launch a new era of integrated, learning-centered assessment systems.

Integrating geo-referenced multiscale and multidisciplinary data for the management of biodiversity in livestock genetic resources.

PubMed

Joost, S; Colli, L; Baret, P V; Garcia, J F; Boettcher, P J; Tixier-Boichard, M; Ajmone-Marsan, P

2010-05-01

In livestock genetic resource conservation, decision making about conservation priorities is based on the simultaneous analysis of several different criteria that may contribute to long-term sustainable breeding conditions, such as genetic and demographic characteristics, environmental conditions, and role of the breed in the local or regional economy. Here we address methods to integrate different data sets and highlight problems related to interdisciplinary comparisons. Data integration is based on the use of geographic coordinates and Geographic Information Systems (GIS). In addition to technical problems related to projection systems, GIS have to face the challenging issue of the non homogeneous scale of their data sets. We give examples of the successful use of GIS for data integration and examine the risk of obtaining biased results when integrating datasets that have been captured at different scales.

Applying systems engineering methodologies to the micro- and nanoscale realm

NASA Astrophysics Data System (ADS)

Garrison Darrin, M. Ann

2012-06-01

Micro scale and nano scale technology developments have the potential to revolutionize smart and small systems. The application of systems engineering methodologies that integrate standalone, small-scale technologies and interface them with macro technologies to build useful systems is critical to realizing the potential of these technologies. This paper covers the expanding knowledge base on systems engineering principles for micro and nano technology integration starting with a discussion of the drivers for applying a systems approach. Technology development on the micro and nano scale has transition from laboratory curiosity to the realization of products in the health, automotive, aerospace, communication, and numerous other arenas. This paper focuses on the maturity (or lack thereof) of the field of nanosystems which is emerging in a third generation having transitioned from completing active structures to creating systems. The emphasis of applying a systems approach focuses on successful technology development based on the lack of maturity of current nano scale systems. Therefore the discussion includes details relating to enabling roles such as product systems engineering and technology development. Classical roles such as acquisition systems engineering are not covered. The results are also targeted towards small-scale technology developers who need to take into account systems engineering processes such as requirements definition, verification, and validation interface management and risk management in the concept phase of technology development to maximize the likelihood of success, cost effective micro and nano technology to increase the capability of emerging deployed systems and long-term growth and profits.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dale, Virginia H; Kline, Keith L; Kaffka, Stephen R

Landscape sustainability of agricultural systems considers effects of farm activities on social, economic, and ecosystem services at local and regional scales. Sustainable agriculture entails: defining sustainability, developing easily measured indicators of sustainability, moving toward integrated agricultural systems, and offering incentives or imposing regulations to affect farmer behavior. A landscape perspective is useful because landscape ecology provides theory and methods for dealing with spatial heterogeneity, scaling, integration, and complexity. To implement agricultural sustainability, we propose adopting a systems perspective, recognizing spatial heterogeneity, addressing the influences of context, and integrating landscape-design principles. Topics that need further attention at local and regional scalesmore » include (1) protocols for quantifying material and energy flows; (2) effects of management practices; (3) incentives for enhancing social, economic, and ecosystem services; (4) integrated landscape planning and management; (5) monitoring and assessment; (6) effects of societal demand; and (7) consistent and holistic policies for promoting agricultural sustainability.« less

On-chip detection of non-classical light by scalable integration of single-photon detectors

PubMed Central

Najafi, Faraz; Mower, Jacob; Harris, Nicholas C.; Bellei, Francesco; Dane, Andrew; Lee, Catherine; Hu, Xiaolong; Kharel, Prashanta; Marsili, Francesco; Assefa, Solomon; Berggren, Karl K.; Englund, Dirk

2015-01-01

Photonic-integrated circuits have emerged as a scalable platform for complex quantum systems. A central goal is to integrate single-photon detectors to reduce optical losses, latency and wiring complexity associated with off-chip detectors. Superconducting nanowire single-photon detectors (SNSPDs) are particularly attractive because of high detection efficiency, sub-50-ps jitter and nanosecond-scale reset time. However, while single detectors have been incorporated into individual waveguides, the system detection efficiency of multiple SNSPDs in one photonic circuit—required for scalable quantum photonic circuits—has been limited to <0.2%. Here we introduce a micrometer-scale flip-chip process that enables scalable integration of SNSPDs on a range of photonic circuits. Ten low-jitter detectors are integrated on one circuit with 100% device yield. With an average system detection efficiency beyond 10%, and estimated on-chip detection efficiency of 14–52% for four detectors operated simultaneously, we demonstrate, to the best of our knowledge, the first on-chip photon correlation measurements of non-classical light. PMID:25575346

Grid-scale Indirect Radiative Forcing of Climate due to aerosols over the northern hemisphere simulated by the integrated WRF-CMAQ model: Preliminary results

EPA Science Inventory

In this study, indirect aerosol effects on grid-scale clouds were implemented in the integrated WRF3.3-CMAQ5.0 modeling system by including parameterizations for both cloud droplet and ice number concentrations calculated from the CMAQ-predicted aerosol particles. The resulting c...

Scale relativity theory and integrative systems biology: 2. Macroscopic quantum-type mechanics.

PubMed

Nottale, Laurent; Auffray, Charles

2008-05-01

In these two companion papers, we provide an overview and a brief history of the multiple roots, current developments and recent advances of integrative systems biology and identify multiscale integration as its grand challenge. Then we introduce the fundamental principles and the successive steps that have been followed in the construction of the scale relativity theory, which aims at describing the effects of a non-differentiable and fractal (i.e., explicitly scale dependent) geometry of space-time. The first paper of this series was devoted, in this new framework, to the construction from first principles of scale laws of increasing complexity, and to the discussion of some tentative applications of these laws to biological systems. In this second review and perspective paper, we describe the effects induced by the internal fractal structures of trajectories on motion in standard space. Their main consequence is the transformation of classical dynamics into a generalized, quantum-like self-organized dynamics. A Schrödinger-type equation is derived as an integral of the geodesic equation in a fractal space. We then indicate how gauge fields can be constructed from a geometric re-interpretation of gauge transformations as scale transformations in fractal space-time. Finally, we introduce a new tentative development of the theory, in which quantum laws would hold also in scale space, introducing complexergy as a measure of organizational complexity. Initial possible applications of this extended framework to the processes of morphogenesis and the emergence of prokaryotic and eukaryotic cellular structures are discussed. Having founded elements of the evolutionary, developmental, biochemical and cellular theories on the first principles of scale relativity theory, we introduce proposals for the construction of an integrative theory of life and for the design and implementation of novel macroscopic quantum-type experiments and devices, and discuss their potential applications for the analysis, engineering and management of physical and biological systems and properties, and the consequences for the organization of transdisciplinary research and the scientific curriculum in the context of the SYSTEMOSCOPE Consortium research and development agenda.

Wafer integrated micro-scale concentrating photovoltaics

NASA Astrophysics Data System (ADS)

Gu, Tian; Li, Duanhui; Li, Lan; Jared, Bradley; Keeler, Gordon; Miller, Bill; Sweatt, William; Paap, Scott; Saavedra, Michael; Das, Ujjwal; Hegedus, Steve; Tauke-Pedretti, Anna; Hu, Juejun

2017-09-01

Recent development of a novel micro-scale PV/CPV technology is presented. The Wafer Integrated Micro-scale PV approach (WPV) seamlessly integrates multijunction micro-cells with a multi-functional silicon platform that provides optical micro-concentration, hybrid photovoltaic, and mechanical micro-assembly. The wafer-embedded micro-concentrating elements is shown to considerably improve the concentration-acceptance-angle product, potentially leading to dramatically reduced module materials and fabrication costs, sufficient angular tolerance for low-cost trackers, and an ultra-compact optical architecture, which makes the WPV module compatible with commercial flat panel infrastructures. The PV/CPV hybrid architecture further allows the collection of both direct and diffuse sunlight, thus extending the geographic and market domains for cost-effective PV system deployment. The WPV approach can potentially benefits from both the high performance of multijunction cells and the low cost of flat plate Si PV systems.

Chip-scale integrated optical interconnects: a key enabler for future high-performance computing

NASA Astrophysics Data System (ADS)

Haney, Michael; Nair, Rohit; Gu, Tian

2012-01-01

High Performance Computing (HPC) systems are putting ever-increasing demands on the throughput efficiency of their interconnection fabrics. In this paper, the limits of conventional metal trace-based inter-chip interconnect fabrics are examined in the context of state-of-the-art HPC systems, which currently operate near the 1 GFLOPS/W level. The analysis suggests that conventional metal trace interconnects will limit performance to approximately 6 GFLOPS/W in larger HPC systems that require many computer chips to be interconnected in parallel processing architectures. As the HPC communications bottlenecks push closer to the processing chips, integrated Optical Interconnect (OI) technology may provide the ultra-high bandwidths needed at the inter- and intra-chip levels. With inter-chip photonic link energies projected to be less than 1 pJ/bit, integrated OI is projected to enable HPC architecture scaling to the 50 GFLOPS/W level and beyond - providing a path to Peta-FLOPS-level HPC within a single rack, and potentially even Exa-FLOPSlevel HPC for large systems. A new hybrid integrated chip-scale OI approach is described and evaluated. The concept integrates a high-density polymer waveguide fabric directly on top of a multiple quantum well (MQW) modulator array that is area-bonded to the Silicon computing chip. Grayscale lithography is used to fabricate 5 μm x 5 μm polymer waveguides and associated novel small-footprint total internal reflection-based vertical input/output couplers directly onto a layer containing an array of GaAs MQW devices configured to be either absorption modulators or photodetectors. An external continuous wave optical "power supply" is coupled into the waveguide links. Contrast ratios were measured using a test rider chip in place of a Silicon processing chip. The results suggest that sub-pJ/b chip-scale communication is achievable with this concept. When integrated into high-density integrated optical interconnect fabrics, it could provide a seamless interconnect fabric spanning the intra-

Thermalization threshold in models of 1D fermions

NASA Astrophysics Data System (ADS)

Mukerjee, Subroto; Modak, Ranjan; Ramswamy, Sriram

2013-03-01

The question of how isolated quantum systems thermalize is an interesting and open one. In this study we equate thermalization with non-integrability to try to answer this question. In particular, we study the effect of system size on the integrability of 1D systems of interacting fermions on a lattice. We find that for a finite-sized system, a non-zero value of an integrability breaking parameter is required to make an integrable system appear non-integrable. Using exact diagonalization and diagnostics such as energy level statistics and the Drude weight, we find that the threshold value of the integrability breaking parameter scales to zero as a power law with system size. We find the exponent to be the same for different models with its value depending on the random matrix ensemble describing the non-integrable system. We also study a simple analytical model of a non-integrable system with an integrable limit to better understand how a power law emerges.

Millimeter-scale MEMS enabled autonomous systems: system feasibility and mobility

NASA Astrophysics Data System (ADS)

Pulskamp, Jeffrey S.

2012-06-01

Millimeter-scale robotic systems based on highly integrated microelectronics and micro-electromechanical systems (MEMS) could offer unique benefits and attributes for small-scale autonomous systems. This extreme scale for robotics will naturally constrain the realizable system capabilities significantly. This paper assesses the feasibility of developing such systems by defining the fundamental design trade spaces between component design variables and system level performance parameters. This permits the development of mobility enabling component technologies within a system relevant context. Feasible ranges of system mass, required aerodynamic power, available battery power, load supported power, flight endurance, and required leg load bearing capability are presented for millimeter-scale platforms. The analysis illustrates the feasibility of developing both flight capable and ground mobile millimeter-scale autonomous systems while highlighting the significant challenges that must be overcome to realize their potential.

Large-Scale Document Automation: The Systems Integration Issue.

ERIC Educational Resources Information Center

Kalthoff, Robert J.

1985-01-01

Reviews current technologies for electronic imaging and its recording and transmission, including digital recording, optical data disks, automated image-delivery micrographics, high-density-magnetic recording, and new developments in telecommunications and computers. The role of the document automation systems integrator, who will bring these…

Manufacturing Laboratory | Energy Systems Integration Facility | NREL

Science.gov Websites

Manufacturing Laboratory Manufacturing Laboratory Researchers in the Energy Systems Integration Facility's Manufacturing Laboratory develop methods and technologies to scale up renewable energy technology manufacturing capabilities. Photo of researchers and equipment in the Manufacturing Laboratory. Capability Hubs

Integration Science and Technology of Advanced Ceramics for Energy and Environmental Applications

NASA Technical Reports Server (NTRS)

Singh, M.

2012-01-01

The discovery of new and innovative materials has been known to culminate in major turning points in human history. The transformative impact and functional manifestation of new materials have been demonstrated in every historical era by their integration into new products, systems, assemblies, and devices. In modern times, the integration of new materials into usable products has a special relevance for the technological development and economic competitiveness of industrial societies. Advanced ceramic technologies dramatically impact the energy and environmental landscape due to potential wide scale applications in all aspects of energy production, storage, distribution, conservation, and efficiency. Examples include gas turbine propulsion systems, fuel cells, thermoelectrics, photovoltaics, distribution and transmission systems based on superconductors, nuclear power generation, and waste disposal. Robust ceramic integration technologies enable hierarchical design and manufacturing of intricate ceramic components starting with geometrically simpler units that are subsequently joined to themselves and/or to metals to create components with progressively higher levels of complexity and functionality. However, for the development of robust and reliable integrated systems with optimum performance under different operating conditions, the detailed understanding of various thermochemical and thermomechanical factors is critical. Different approaches are required for the integration of ceramic-metal and ceramic-ceramic systems across length scales (macro to nano). In this presentation, a few examples of integration of ceramic to metals and ceramic to ceramic systems will be presented. Various challenges and opportunities in design, fabrication, and testing of integrated similar (ceramic-ceramic) and dissimilar (ceramic-metal) material systems will be discussed. Potential opportunities and need for the development of innovative design philosophies, approaches, and integrated system testing under simulated application conditions will also be presented.

Analyzing Distributed Functions in an Integrated Hazard Analysis

NASA Technical Reports Server (NTRS)

Morris, A. Terry; Massie, Michael J.

2010-01-01

Large scale integration of today's aerospace systems is achievable through the use of distributed systems. Validating the safety of distributed systems is significantly more difficult as compared to centralized systems because of the complexity of the interactions between simultaneously active components. Integrated hazard analysis (IHA), a process used to identify unacceptable risks and to provide a means of controlling them, can be applied to either centralized or distributed systems. IHA, though, must be tailored to fit the particular system being analyzed. Distributed systems, for instance, must be analyzed for hazards in terms of the functions that rely on them. This paper will describe systems-oriented IHA techniques (as opposed to traditional failure-event or reliability techniques) that should be employed for distributed systems in aerospace environments. Special considerations will be addressed when dealing with specific distributed systems such as active thermal control, electrical power, command and data handling, and software systems (including the interaction with fault management systems). Because of the significance of second-order effects in large scale distributed systems, the paper will also describe how to analyze secondary functions to secondary functions through the use of channelization.

Integrating Bioregenerative Foods into the Exploration Spaceflight Food System

NASA Technical Reports Server (NTRS)

Douglas, Grace L.

2017-01-01

Food, the nutrition it provides, and the eating experiences surrounding it, are central to performance, health, and psychosocial wellbeing on long duration spaceflight missions. Exploration missions will require a spaceflight food system that is safe, nutritious, and acceptable for up to five years, possibly without cold storage. Many of the processed and packaged spaceflight foods currently used on the International Space Station will not retain acceptable quality or required levels of key nutrients under these conditions. The addition of bioregenerative produce to exploration missions may become an important countermeasure to the nutritional gaps and a resource to support psychosocial health. Bioregenerative produce will be central to establishment of Earth-independence as exploration extends deeper into space. However, bioregenerative foods introduce food safety and scarcity risks that must be eliminated prior to crew reliance on these systems. The pathway to Earth independence will require small-scale integration and validation prior to large scale bioregenerative dependence. Near term exploration missions offer the opportunity to establish small scale supplemental salad crop and fruit systems and validate infrastructure reliability, nutritional potential, and the psychosocial benefits necessary to promote further bioregenerative integration.

Are galaxy distributions scale invariant? A perspective from dynamical systems theory

NASA Astrophysics Data System (ADS)

McCauley, J. L.

2002-06-01

Unless there is an evidence for fractal scaling with a single exponent over distances 0.1<=r<=100h-1Mpc, then the widely accepted notion of scale invariance of the correlation integral for 0.1<=r<=10h-1Mpc must be questioned. The attempt to extract a scaling exponent /ν from the correlation integral /n(r) by plotting /log(n(r)) vs. /log(r) is unreliable unless the underlying point set is approximately monofractal. The extraction of a spectrum of generalized dimensions νq from a plot of the correlation integral generating function Gn(q) by a similar procedure is probably an indication that Gn(q) does not scale at all. We explain these assertions after defining the term multifractal, mutually inconsistent definitions having been confused together in the cosmology literature. Part of this confusion is traced to the confusion in interpreting a measure-theoretic formula written down by Hentschel and Procaccia in the dynamical systems theory literature, while other errors follow from confusing together entirely different definitions of multifractal from two different schools of thought. Most important are serious errors in data analysis that follow from taking for granted a largest term approximation that is inevitably advertised in the literature on both fractals and dynamical systems theory.

MULTIMEDIA INTEGRATED MODELING FOR ENVIRONMENTAL PROTECTION: INTRODUCTION TO A COLLABORATIVE FRAMEWORK

EPA Science Inventory

The EPA's Office of Research and Development is embarking on a long term project to develop a Multimedia Integrated Modeling System (MIMS). The system will have capabilities to represent the transport and fate of nutrients and chemical stressors over multiple scales. MIMS will ...

Cross-scale phenological data integration to benefit resource management and monitoring

USGS Publications Warehouse

Richardson, Andrew D.; Weltzin, Jake F.; Morisette, Jeffrey T.

2017-01-01

Climate change is presenting new challenges for natural resource managers charged with maintaining sustainable ecosystems and landscapes. Phenology, a branch of science dealing with seasonal natural phenomena (bird migration or plant flowering in response to weather changes, for example), bridges the gap between the biosphere and the climate system. Phenological processes operate across scales that span orders of magnitude—from leaf to globe and from days to seasons—making phenology ideally suited to multiscale, multiplatform data integration and delivery of information at spatial and temporal scales suitable to inform resource management decisions.A workshop report: Workshop held June 2016 to investigate opportunities and challenges facing multi-scale, multi-platform integration of phenological data to support natural resource management decision-making.

Prospective and participatory integrated assessment of agricultural systems from farm to regional scales: Comparison of three modeling approaches.

PubMed

Delmotte, Sylvestre; Lopez-Ridaura, Santiago; Barbier, Jean-Marc; Wery, Jacques

2013-11-15

Evaluating the impacts of the development of alternative agricultural systems, such as organic or low-input cropping systems, in the context of an agricultural region requires the use of specific tools and methodologies. They should allow a prospective (using scenarios), multi-scale (taking into account the field, farm and regional level), integrated (notably multicriteria) and participatory assessment, abbreviated PIAAS (for Participatory Integrated Assessment of Agricultural System). In this paper, we compare the possible contribution to PIAAS of three modeling approaches i.e. Bio-Economic Modeling (BEM), Agent-Based Modeling (ABM) and statistical Land-Use/Land Cover Change (LUCC) models. After a presentation of each approach, we analyze their advantages and drawbacks, and identify their possible complementarities for PIAAS. Statistical LUCC modeling is a suitable approach for multi-scale analysis of past changes and can be used to start discussion about the futures with stakeholders. BEM and ABM approaches have complementary features for scenarios assessment at different scales. While ABM has been widely used for participatory assessment, BEM has been rarely used satisfactorily in a participatory manner. On the basis of these results, we propose to combine these three approaches in a framework targeted to PIAAS. Copyright © 2013 Elsevier Ltd. All rights reserved.

Low rank factorization of the Coulomb integrals for periodic coupled cluster theory.

PubMed

Hummel, Felix; Tsatsoulis, Theodoros; Grüneis, Andreas

2017-03-28

We study a tensor hypercontraction decomposition of the Coulomb integrals of periodic systems where the integrals are factorized into a contraction of six matrices of which only two are distinct. We find that the Coulomb integrals can be well approximated in this form already with small matrices compared to the number of real space grid points. The cost of computing the matrices scales as O(N 4 ) using a regularized form of the alternating least squares algorithm. The studied factorization of the Coulomb integrals can be exploited to reduce the scaling of the computational cost of expensive tensor contractions appearing in the amplitude equations of coupled cluster methods with respect to system size. We apply the developed methodologies to calculate the adsorption energy of a single water molecule on a hexagonal boron nitride monolayer in a plane wave basis set and periodic boundary conditions.

A design for integration.

PubMed

Fenna, D

1977-09-01

For nearly two decades, the development of computerized information systems has struggled for acceptable compromises between the unattainable "total system" and the unacceptable separate applications. Integration of related applications is essential if the computer is to be exploited fully, yet relative simplicity is necessary for systems to be implemented in a reasonable time-scale. This paper discusses a system being progressively developed from minimal beginnings but which, from the outset, had a highly flexible and fully integrated system basis. The system is for batch processing, but can accommodate on-line data input; it is similar in its approach to many transaction-processing real-time systems.

Low-Activity Waste Pretreatment System Additional Engineering-Scale Integrated Test Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Landon, Matt R.; Wilson, Robert A.

Washington River Protections Solutions, LLC’s (WRPS) Low Activity Waste Pretreatment System (LAWPS) Project provides for the early production of immobilized low-activity waste (ILAW) by feeding LAW directly from Tank Farms to the Waste Treatment and Immobilization Plant (WTP) LAW Facility, bypassing the WTP Pretreatment Facility. Prior to the transfer of feed to the WTP LAW Vitrification Facility, tank supernatant waste will be pretreated in the LAWPS to meet the WTP LAW waste acceptance criteria (WAC). Full-scale and engineering-scale testing of critical technology elements, as part of the technology maturation process, are components of the overall LAWPS Project. WRPS awarded themore » engineering-scale integrated testing scope to AECOM via WRPS Subcontract 58349. This report is deliverable MSR-008 of the subcontract.« less

Scaled Runge-Kutta algorithms for handling dense output

NASA Technical Reports Server (NTRS)

Horn, M. K.

1981-01-01

Low order Runge-Kutta algorithms are developed which determine the solution of a system of ordinary differential equations at any point within a given integration step, as well as at the end of each step. The scaled Runge-Kutta methods are designed to be used with existing Runge-Kutta formulas, using the derivative evaluations of these defining algorithms as the core of the system. For a slight increase in computing time, the solution may be generated within the integration step, improving the efficiency of the Runge-Kutta algorithms, since the step length need no longer be severely reduced to coincide with the desired output point. Scaled Runge-Kutta algorithms are presented for orders 3 through 5, along with accuracy comparisons between the defining algorithms and their scaled versions for a test problem.

Improving predictions of large scale soil carbon dynamics: Integration of fine-scale hydrological and biogeochemical processes, scaling, and benchmarking

NASA Astrophysics Data System (ADS)

Riley, W. J.; Dwivedi, D.; Ghimire, B.; Hoffman, F. M.; Pau, G. S. H.; Randerson, J. T.; Shen, C.; Tang, J.; Zhu, Q.

2015-12-01

Numerical model representations of decadal- to centennial-scale soil-carbon dynamics are a dominant cause of uncertainty in climate change predictions. Recent attempts by some Earth System Model (ESM) teams to integrate previously unrepresented soil processes (e.g., explicit microbial processes, abiotic interactions with mineral surfaces, vertical transport), poor performance of many ESM land models against large-scale and experimental manipulation observations, and complexities associated with spatial heterogeneity highlight the nascent nature of our community's ability to accurately predict future soil carbon dynamics. I will present recent work from our group to develop a modeling framework to integrate pore-, column-, watershed-, and global-scale soil process representations into an ESM (ACME), and apply the International Land Model Benchmarking (ILAMB) package for evaluation. At the column scale and across a wide range of sites, observed depth-resolved carbon stocks and their 14C derived turnover times can be explained by a model with explicit representation of two microbial populations, a simple representation of mineralogy, and vertical transport. Integrating soil and plant dynamics requires a 'process-scaling' approach, since all aspects of the multi-nutrient system cannot be explicitly resolved at ESM scales. I will show that one approach, the Equilibrium Chemistry Approximation, improves predictions of forest nitrogen and phosphorus experimental manipulations and leads to very different global soil carbon predictions. Translating model representations from the site- to ESM-scale requires a spatial scaling approach that either explicitly resolves the relevant processes, or more practically, accounts for fine-resolution dynamics at coarser scales. To that end, I will present recent watershed-scale modeling work that applies reduced order model methods to accurately scale fine-resolution soil carbon dynamics to coarse-resolution simulations. Finally, we contend that creating believable soil carbon predictions requires a robust, transparent, and community-available benchmarking framework. I will present an ILAMB evaluation of several of the above-mentioned approaches in ACME, and attempt to motivate community adoption of this evaluation approach.

A multi-scale metrics approach to forest fragmentation for Strategic Environmental Impact Assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Eunyoung, E-mail: eykim@kei.re.kr; Song, Wonkyong, E-mail: wksong79@gmail.com; Lee, Dongkun, E-mail: dklee7@snu.ac.kr

Forests are becoming severely fragmented as a result of land development. South Korea has responded to changing community concerns about environmental issues. The nation has developed and is extending a broad range of tools for use in environmental management. Although legally mandated environmental compliance requirements in South Korea have been implemented to predict and evaluate the impacts of land-development projects, these legal instruments are often insufficient to assess the subsequent impact of development on the surrounding forests. It is especially difficult to examine impacts on multiple (e.g., regional and local) scales in detail. Forest configuration and size, including forest fragmentationmore » by land development, are considered on a regional scale. Moreover, forest structure and composition, including biodiversity, are considered on a local scale in the Environmental Impact Assessment process. Recently, the government amended the Environmental Impact Assessment Act, including the SEA, EIA, and small-scale EIA, to require an integrated approach. Therefore, the purpose of this study was to establish an impact assessment system that minimizes the impacts of land development using an approach that is integrated across multiple scales. This study focused on forest fragmentation due to residential development and road construction sites in selected Congestion Restraint Zones (CRZs) in the Greater Seoul Area of South Korea. Based on a review of multiple-scale impacts, this paper integrates models that assess the impacts of land development on forest ecosystems. The applicability of the integrated model for assessing impacts on forest ecosystems through the SEIA process is considered. On a regional scale, it is possible to evaluate the location and size of a land-development project by considering aspects of forest fragmentation, such as the stability of the forest structure and the degree of fragmentation. On a local scale, land-development projects should consider the distances at which impacts occur in the vicinity of the forest ecosystem, and these considerations should include the impacts on forest vegetation and bird species. Impacts can be mitigated by considering the distances at which these influences occur. In particular, this paper presents an integrated environmental impact assessment system to be applied in the SEIA process. The integrated assessment system permits the assessment of the cumulative impacts of land development on multiple scales. -- Highlights: • The model is to assess the impact of forest fragmentation across multiple scales. • The paper suggests the type of forest fragmentation on a regional scale. • The type can be used to evaluate the location and size of a land development. • The paper shows the influence distance of land development on a local scale. • The distance can be used to mitigate the impact at an EIA process.« less

On the performance of exponential integrators for problems in magnetohydrodynamics

NASA Astrophysics Data System (ADS)

Einkemmer, Lukas; Tokman, Mayya; Loffeld, John

2017-02-01

Exponential integrators have been introduced as an efficient alternative to explicit and implicit methods for integrating large stiff systems of differential equations. Over the past decades these methods have been studied theoretically and their performance was evaluated using a range of test problems. While the results of these investigations showed that exponential integrators can provide significant computational savings, the research on validating this hypothesis for large scale systems and understanding what classes of problems can particularly benefit from the use of the new techniques is in its initial stages. Resistive magnetohydrodynamic (MHD) modeling is widely used in studying large scale behavior of laboratory and astrophysical plasmas. In many problems numerical solution of MHD equations is a challenging task due to the temporal stiffness of this system in the parameter regimes of interest. In this paper we evaluate the performance of exponential integrators on large MHD problems and compare them to a state-of-the-art implicit time integrator. Both the variable and constant time step exponential methods of EPIRK-type are used to simulate magnetic reconnection and the Kevin-Helmholtz instability in plasma. Performance of these methods, which are part of the EPIC software package, is compared to the variable time step variable order BDF scheme included in the CVODE (part of SUNDIALS) library. We study performance of the methods on parallel architectures and with respect to magnitudes of important parameters such as Reynolds, Lundquist, and Prandtl numbers. We find that the exponential integrators provide superior or equal performance in most circumstances and conclude that further development of exponential methods for MHD problems is warranted and can lead to significant computational advantages for large scale stiff systems of differential equations such as MHD.

Poincaré-Treshchev Mechanism in Multi-scale, Nearly Integrable Hamiltonian Systems

NASA Astrophysics Data System (ADS)

Xu, Lu; Li, Yong; Yi, Yingfei

2018-02-01

This paper is a continuation to our work (Xu et al. in Ann Henri Poincaré 18(1):53-83, 2017) concerning the persistence of lower-dimensional tori on resonant surfaces of a multi-scale, nearly integrable Hamiltonian system. This type of systems, being properly degenerate, arise naturally in planar and spatial lunar problems of celestial mechanics for which the persistence problem ties closely to the stability of the systems. For such a system, under certain non-degenerate conditions of Rüssmann type, the majority persistence of non-resonant tori and the existence of a nearly full measure set of Poincaré non-degenerate, lower-dimensional, quasi-periodic invariant tori on a resonant surface corresponding to the highest order of scale is proved in Han et al. (Ann Henri Poincaré 10(8):1419-1436, 2010) and Xu et al. (2017), respectively. In this work, we consider a resonant surface corresponding to any intermediate order of scale and show the existence of a nearly full measure set of Poincaré non-degenerate, lower-dimensional, quasi-periodic invariant tori on the resonant surface. The proof is based on a normal form reduction which consists of a finite step of KAM iterations in pushing the non-integrable perturbation to a sufficiently high order and the splitting of resonant tori on the resonant surface according to the Poincaré-Treshchev mechanism.

Optical printed circuit board (O-PCB) and VLSI photonic integrated circuits: visions, challenges, and progresses

NASA Astrophysics Data System (ADS)

Lee, El-Hang; Lee, S. G.; O, B. H.; Park, S. G.; Noh, H. S.; Kim, K. H.; Song, S. H.

2006-09-01

A collective overview and review is presented on the original work conducted on the theory, design, fabrication, and in-tegration of micro/nano-scale optical wires and photonic devices for applications in a newly-conceived photonic systems called "optical printed circuit board" (O-PCBs) and "VLSI photonic integrated circuits" (VLSI-PIC). These are aimed for compact, high-speed, multi-functional, intelligent, light-weight, low-energy and environmentally friendly, low-cost, and high-volume applications to complement or surpass the capabilities of electrical PCBs (E-PCBs) and/or VLSI electronic integrated circuit (VLSI-IC) systems. These consist of 2-dimensional or 3-dimensional planar arrays of micro/nano-optical wires and circuits to perform the functions of all-optical sensing, storing, transporting, processing, switching, routing and distributing optical signals on flat modular boards or substrates. The integrated optical devices include micro/nano-scale waveguides, lasers, detectors, switches, sensors, directional couplers, multi-mode interference devices, ring-resonators, photonic crystal devices, plasmonic devices, and quantum devices, made of polymer, silicon and other semiconductor materials. For VLSI photonic integration, photonic crystals and plasmonic structures have been used. Scientific and technological issues concerning the processes of miniaturization, interconnection and integration of these systems as applicable to board-to-board, chip-to-chip, and intra-chip integration, are discussed along with applications for future computers, telecommunications, and sensor-systems. Visions and challenges toward these goals are also discussed.

Grid Research | Grid Modernization | NREL

Science.gov Websites

Grid Research Grid Research NREL addresses the challenges of today's electric grid through high researcher in a lab Integrated Devices and Systems Developing and evaluating grid technologies and integrated Controls Developing methods for real-time operations and controls of power systems at any scale Photo of

Integration of Personalized Healthcare Pathways in an ICT Platform for Diabetes Managements: A Small-Scale Exploratory Study.

PubMed

Fico, Giuseppe; Fioravanti, Alessio; Arredondo, Maria Teresa; Gorman, Joe; Diazzi, Chiara; Arcuri, Giovanni; Conti, Claudio; Pirini, Giampiero

2016-01-01

The availability of new tools able to support patient monitoring and personalized care may substantially improve the quality of chronic disease management. A personalized healthcare pathway (PHP) has been developed for diabetes disease management and integrated into an information and communication technology system to accomplish a shift from organization-centered care to patient-centered care. A small-scale exploratory study was conducted to test the platform. Preliminary results are presented that shed light on how the PHP influences system usage and performance outcomes.

An integrated view of complex landscapes: a big data-model integration approach to trans-disciplinary science

USDA-ARS?s Scientific Manuscript database

The Earth is a complex system comprised of many interacting spatial and temporal scales. Understanding, predicting, and managing for these dynamics requires a trans-disciplinary integrated approach. Although there have been calls for this integration, a general approach is needed. We developed a Tra...

Finite-size scaling of eigenstate thermalization

NASA Astrophysics Data System (ADS)

Beugeling, W.; Moessner, R.; Haque, Masudul

2014-04-01

According to the eigenstate thermalization hypothesis (ETH), even isolated quantum systems can thermalize because the eigenstate-to-eigenstate fluctuations of typical observables vanish in the limit of large systems. Of course, isolated systems are by nature finite and the main way of computing such quantities is through numerical evaluation for finite-size systems. Therefore, the finite-size scaling of the fluctuations of eigenstate expectation values is a central aspect of the ETH. In this work, we present numerical evidence that for generic nonintegrable systems these fluctuations scale with a universal power law D-1/2 with the dimension D of the Hilbert space. We provide heuristic arguments, in the same spirit as the ETH, to explain this universal result. Our results are based on the analysis of three families of models and several observables for each model. Each family includes integrable members and we show how the system size where the universal power law becomes visible is affected by the proximity to integrability.

Silvicultural options for neotropical migratory birds

Treesearch

Frank R. Thompson; John R. Probst; Martin G. Raphael

1993-01-01

We review: factors that affect forest bird populations; basic concepts of silvicultural systems; potential impacts of these systems on neotropical migratory birds (NTMBs); and conclude with management recommendations for integrating NTMB conservation with forest management. We approach this topic from a regional-landscape scale to a forest stand-habitat scale, rather...

Reducing Manpower for a Technologically Advanced Ship

DTIC Science & Technology

2010-01-27

Watchstations by 84% (119 to 34) “ Autonomic ” Fire Suppression System AFSS is designed to automatically: (1) Isolate damage to firemain piping... System (IPS) Advanced VLS Autonomic Fire Suppression Hull Form Scale Models Total Ship Computing Environment (TSCE) Integrated Undersea...Warfare (IUSW) System ( AFSS ) 8 Total Ship Organization Ship C3I Engage Support Technical Director TSCEI Sense Integrated Product Teams TSSE Director

IMGMD: A platform for the integration and standardisation of In silico Microbial Genome-scale Metabolic Models.

PubMed

Ye, Chao; Xu, Nan; Dong, Chuan; Ye, Yuannong; Zou, Xuan; Chen, Xiulai; Guo, Fengbiao; Liu, Liming

2017-04-07

Genome-scale metabolic models (GSMMs) constitute a platform that combines genome sequences and detailed biochemical information to quantify microbial physiology at the system level. To improve the unity, integrity, correctness, and format of data in published GSMMs, a consensus IMGMD database was built in the LAMP (Linux + Apache + MySQL + PHP) system by integrating and standardizing 328 GSMMs constructed for 139 microorganisms. The IMGMD database can help microbial researchers download manually curated GSMMs, rapidly reconstruct standard GSMMs, design pathways, and identify metabolic targets for strategies on strain improvement. Moreover, the IMGMD database facilitates the integration of wet-lab and in silico data to gain an additional insight into microbial physiology. The IMGMD database is freely available, without any registration requirements, at http://imgmd.jiangnan.edu.cn/database.

VLSI (Very Large Scale Integrated) Design of a 16 Bit Very Fast Pipelined Carry Look Ahead Adder.

DTIC Science & Technology

1983-09-01

the ability for systems engineers to custom design digital integrated circuits. Until recently, the design of integrated circuits has been...traditionally carried out by a select group of logic designers working in semiconductor laboratories. Systems engineers had to "make do" or "fit in" the...products of these labs to realize their designs. The systems engineers had little participation in the actual design of the chip. The MED and CONWAY design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shahidehpour, Mohammad

Integrating 20% or more wind energy into the system and transmitting large sums of wind energy over long distances will require a decision making capability that can handle very large scale power systems with tens of thousands of buses and lines. There is a need to explore innovative analytical and implementation solutions for continuing reliable operations with the most economical integration of additional wind energy in power systems. A number of wind integration solution paths involve the adoption of new operating policies, dynamic scheduling of wind power across interties, pooling integration services, and adopting new transmission scheduling practices. Such practicesmore » can be examined by the decision tool developed by this project. This project developed a very efficient decision tool called Wind INtegration Simulator (WINS) and applied WINS to facilitate wind energy integration studies. WINS focused on augmenting the existing power utility capabilities to support collaborative planning, analysis, and wind integration project implementations. WINS also had the capability of simulating energy storage facilities so that feasibility studies of integrated wind energy system applications can be performed for systems with high wind energy penetrations. The development of WINS represents a major expansion of a very efficient decision tool called POwer Market Simulator (POMS), which was developed by IIT and has been used extensively for power system studies for decades. Specifically, WINS provides the following superiorities; (1) An integrated framework is included in WINS for the comprehensive modeling of DC transmission configurations, including mono-pole, bi-pole, tri-pole, back-to-back, and multi-terminal connection, as well as AC/DC converter models including current source converters (CSC) and voltage source converters (VSC); (2) An existing shortcoming of traditional decision tools for wind integration is the limited availability of user interface, i.e., decision results are often text-based demonstrations. WINS includes a powerful visualization tool and user interface capability for transmission analyses, planning, and assessment, which will be of great interest to power market participants, power system planners and operators, and state and federal regulatory entities; and (3) WINS can handle extended transmission models for wind integration studies. WINS models include limitations on transmission flow as well as bus voltage for analyzing power system states. The existing decision tools often consider transmission flow constraints (dc power flow) alone which could result in the over-utilization of existing resources when analyzing wind integration. WINS can be used to assist power market participants including transmission companies, independent system operators, power system operators in vertically integrated utilities, wind energy developers, and regulatory agencies to analyze economics, security, and reliability of various options for wind integration including transmission upgrades and the planning of new transmission facilities. WINS can also be used by industry for the offline training of reliability and operation personnel when analyzing wind integration uncertainties, identifying critical spots in power system operation, analyzing power system vulnerabilities, and providing credible decisions for examining operation and planning options for wind integration. Researches in this project on wind integration included (1) Development of WINS; (2) Transmission Congestion Analysis in the Eastern Interconnection; (3) Analysis of 2030 Large-Scale Wind Energy Integration in the Eastern Interconnection; (4) Large-scale Analysis of 2018 Wind Energy Integration in the Eastern U.S. Interconnection. The research resulted in 33 papers, 9 presentations, 9 PhD degrees, 4 MS degrees, and 7 awards. The education activities in this project on wind energy included (1) Wind Energy Training Facility Development; (2) Wind Energy Course Development.« less

Watershed System Model: The Essentials to Model Complex Human-Nature System at the River Basin Scale

NASA Astrophysics Data System (ADS)

Li, Xin; Cheng, Guodong; Lin, Hui; Cai, Ximing; Fang, Miao; Ge, Yingchun; Hu, Xiaoli; Chen, Min; Li, Weiyue

2018-03-01

Watershed system models are urgently needed to understand complex watershed systems and to support integrated river basin management. Early watershed modeling efforts focused on the representation of hydrologic processes, while the next-generation watershed models should represent the coevolution of the water-land-air-plant-human nexus in a watershed and provide capability of decision-making support. We propose a new modeling framework and discuss the know-how approach to incorporate emerging knowledge into integrated models through data exchange interfaces. We argue that the modeling environment is a useful tool to enable effective model integration, as well as create domain-specific models of river basin systems. The grand challenges in developing next-generation watershed system models include but are not limited to providing an overarching framework for linking natural and social sciences, building a scientifically based decision support system, quantifying and controlling uncertainties, and taking advantage of new technologies and new findings in the various disciplines of watershed science. The eventual goal is to build transdisciplinary, scientifically sound, and scale-explicit watershed system models that are to be codesigned by multidisciplinary communities.

Scale and the Evolutionarily Based Approximate Number System: An Exploratory Study

ERIC Educational Resources Information Center

Delgado, Cesar; Jones, M. Gail; You, Hye Sun; Robertson, Laura; Chesnutt, Katherine; Halberda, Justin

2017-01-01

Crosscutting concepts such as "scale, proportion, and quantity" are recognised by U.S. science standards as a potential vehicle for students to integrate their scientific and mathematical knowledge; yet, U.S. students and adults trail their international peers in scale and measurement estimation. Culturally based knowledge of scale such…

The small length scale effect for a non-local cantilever beam: a paradox solved.

PubMed

Challamel, N; Wang, C M

2008-08-27

Non-local continuum mechanics allows one to account for the small length scale effect that becomes significant when dealing with microstructures or nanostructures. This paper presents some simplified non-local elastic beam models, for the bending analyses of small scale rods. Integral-type or gradient non-local models abandon the classical assumption of locality, and admit that stress depends not only on the strain value at that point but also on the strain values of all points on the body. There is a paradox still unresolved at this stage: some bending solutions of integral-based non-local elastic beams have been found to be identical to the classical (local) solution, i.e. the small scale effect is not present at all. One example is the Euler-Bernoulli cantilever nanobeam model with a point load which has application in microelectromechanical systems and nanoelectromechanical systems as an actuator. In this paper, it will be shown that this paradox may be overcome with a gradient elastic model as well as an integral non-local elastic model that is based on combining the local and the non-local curvatures in the constitutive elastic relation. The latter model comprises the classical gradient model and Eringen's integral model, and its application produces small length scale terms in the non-local elastic cantilever beam solution.

Data integration in the era of omics: current and future challenges

PubMed Central

2014-01-01

To integrate heterogeneous and large omics data constitutes not only a conceptual challenge but a practical hurdle in the daily analysis of omics data. With the rise of novel omics technologies and through large-scale consortia projects, biological systems are being further investigated at an unprecedented scale generating heterogeneous and often large data sets. These data-sets encourage researchers to develop novel data integration methodologies. In this introduction we review the definition and characterize current efforts on data integration in the life sciences. We have used a web-survey to assess current research projects on data-integration to tap into the views, needs and challenges as currently perceived by parts of the research community. PMID:25032990

Digital Systems Validation Handbook. Volume 2. Chapter 18. Avionic Data Bus Integration Technology

DTIC Science & Technology

1993-11-01

interaction between a digital data bus and an avionic system. Very Large Scale Integration (VLSI) ICs and multiversion software, which make up digital...1984, the Sperry Corporation developed a fault tolerant system which employed multiversion programming, voting, and monitoring for error detection and...formulate all the significant behavior of a system. MULTIVERSION PROGRAMMING. N-version programming. N-VERSION PROGRAMMING. The independent coding of a

Parallel Multi-Step/Multi-Rate Integration of Two-Time Scale Dynamic Systems

NASA Technical Reports Server (NTRS)

Chang, Johnny T.; Ploen, Scott R.; Sohl, Garett. A,; Martin, Bryan J.

2004-01-01

Increasing demands on the fidelity of simulations for real-time and high-fidelity simulations are stressing the capacity of modern processors. New integration techniques are required that provide maximum efficiency for systems that are parallelizable. However many current techniques make assumptions that are at odds with non-cascadable systems. A new serial multi-step/multi-rate integration algorithm for dual-timescale continuous state systems is presented which applies to these systems, and is extended to a parallel multi-step/multi-rate algorithm. The superior performance of both algorithms is demonstrated through a representative example.

Transforming Power Systems Through Global Collaboration

DOE Office of Scientific and Technical Information (OSTI.GOV)

2017-06-01

Ambitious and integrated policy and regulatory frameworks are crucial to achieve power system transformation. The 21st Century Power Partnership -- a multilateral initiative of the Clean Energy Ministerial -- serves as a platform for public-private collaboration to advance integrated solutions for the large-scale deployment of renewable energy in combination with energy efficiency and grid modernization.

Groundwater modeling in integrated water resources management--visions for 2020.

PubMed

Refsgaard, Jens Christian; Højberg, Anker Lajer; Møller, Ingelise; Hansen, Martin; Søndergaard, Verner

2010-01-01

Groundwater modeling is undergoing a change from traditional stand-alone studies toward being an integrated part of holistic water resources management procedures. This is illustrated by the development in Denmark, where comprehensive national databases for geologic borehole data, groundwater-related geophysical data, geologic models, as well as a national groundwater-surface water model have been established and integrated to support water management. This has enhanced the benefits of using groundwater models. Based on insight gained from this Danish experience, a scientifically realistic scenario for the use of groundwater modeling in 2020 has been developed, in which groundwater models will be a part of sophisticated databases and modeling systems. The databases and numerical models will be seamlessly integrated, and the tasks of monitoring and modeling will be merged. Numerical models for atmospheric, surface water, and groundwater processes will be coupled in one integrated modeling system that can operate at a wide range of spatial scales. Furthermore, the management systems will be constructed with a focus on building credibility of model and data use among all stakeholders and on facilitating a learning process whereby data and models, as well as stakeholders' understanding of the system, are updated to currently available information. The key scientific challenges for achieving this are (1) developing new methodologies for integration of statistical and qualitative uncertainty; (2) mapping geological heterogeneity and developing scaling methodologies; (3) developing coupled model codes; and (4) developing integrated information systems, including quality assurance and uncertainty information that facilitate active stakeholder involvement and learning.

Integral criteria for large-scale multiple fingerprint solutions

NASA Astrophysics Data System (ADS)

Ushmaev, Oleg S.; Novikov, Sergey O.

2004-08-01

We propose the definition and analysis of the optimal integral similarity score criterion for large scale multmodal civil ID systems. Firstly, the general properties of score distributions for genuine and impostor matches for different systems and input devices are investigated. The empirical statistics was taken from the real biometric tests. Then we carry out the analysis of simultaneous score distributions for a number of combined biometric tests and primary for ultiple fingerprint solutions. The explicit and approximate relations for optimal integral score, which provides the least value of the FRR while the FAR is predefined, have been obtained. The results of real multiple fingerprint test show good correspondence with the theoretical results in the wide range of the False Acceptance and the False Rejection Rates.

Scale-dependent behavior of scale equations.

PubMed

Kim, Pilwon

2009-09-01

We propose a new mathematical framework to formulate scale structures of general systems. Stack equations characterize a system in terms of accumulative scales. Their behavior at each scale level is determined independently without referring to other levels. Most standard geometries in mathematics can be reformulated in such stack equations. By involving interaction between scales, we generalize stack equations into scale equations. Scale equations are capable to accommodate various behaviors at different scale levels into one integrated solution. On contrary to standard geometries, such solutions often reveal eccentric scale-dependent figures, providing a clue to understand multiscale nature of the real world. Especially, it is suggested that the Gaussian noise stems from nonlinear scale interactions.

New tools for linking human and earth system models: The Toolbox for Human-Earth System Interaction & Scaling (THESIS)

NASA Astrophysics Data System (ADS)

O'Neill, B. C.; Kauffman, B.; Lawrence, P.

2016-12-01

Integrated analysis of questions regarding land, water, and energy resources often requires integration of models of different types. One type of integration is between human and earth system models, since both societal and physical processes influence these resources. For example, human processes such as changes in population, economic conditions, and policies govern the demand for land, water and energy, while the interactions of these resources with physical systems determine their availability and environmental consequences. We have begun to develop and use a toolkit for linking human and earth system models called the Toolbox for Human-Earth System Integration and Scaling (THESIS). THESIS consists of models and software tools to translate, scale, and synthesize information from and between human system models and earth system models (ESMs), with initial application to linking the NCAR integrated assessment model, iPETS, with the NCAR earth system model, CESM. Initial development is focused on urban areas and agriculture, sectors that are both explicitly represented in both CESM and iPETS. Tools are being made available to the community as they are completed (see https://www2.cgd.ucar.edu/sections/tss/iam/THESIS_tools). We discuss four general types of functions that THESIS tools serve (Spatial Distribution, Spatial Properties, Consistency, and Outcome Evaluation). Tools are designed to be modular and can be combined in order to carry out more complex analyses. We illustrate their application to both the exposure of population to climate extremes and to the evaluation of climate impacts on the agriculture sector. For example, projecting exposure to climate extremes involves use of THESIS tools for spatial population, spatial urban land cover, the characteristics of both, and a tool to bring urban climate information together with spatial population information. Development of THESIS tools is continuing and open to the research community.

Smart wing wind tunnel model design

NASA Astrophysics Data System (ADS)

Martin, Christopher A.; Jasmin, Larry; Flanagan, John S.; Appa, Kari; Kudva, Jayanth N.

1997-05-01

To verify the predicted benefits of the smart wing concept, two 16% scale wind tunnel models, one conventional and the other incorporating smart wing design features, were designed, fabricated and tested. Meticulous design of the two models was essential to: (1) ensure the required factor of safety of four for operation in the NASA Langley TDT wind tunnel, (2) efficiently integrate the smart actuation systems, (3) quantify the performance improvements, and (4) facilitate eventual scale-up to operational aircraft. Significant challenges were encountered in designing the attachment of the shape memory alloy control surfaces to the wing box, integration of the SMA torque tube in the wing structure, and development of control mechanisms to protect the model and the tunnel in the event of failure of the smart systems. In this paper, detailed design of the two models are presented. First, dynamic scaling of the models based on the geometry and structural details of the full- scale aircraft is presented. Next, results of the stress, divergence and flutter analyses are summarized. Finally some of the challenges of integrating the smart actuators with the model are highlighted.

Renewable Fuels-to-Grid Integration | Energy Systems Integration Facility |

Science.gov Websites

hydrogen, other than electrolysis. Read more about this research. Partnerships Photo of a polymer electrolyte membrane stack in a laboratory Giner NREL helped evaluate a large-scale polymer electrolyte

Materials integrity in microsystems: a framework for a petascale predictive-science-based multiscale modeling and simulation system

NASA Astrophysics Data System (ADS)

To, Albert C.; Liu, Wing Kam; Olson, Gregory B.; Belytschko, Ted; Chen, Wei; Shephard, Mark S.; Chung, Yip-Wah; Ghanem, Roger; Voorhees, Peter W.; Seidman, David N.; Wolverton, Chris; Chen, J. S.; Moran, Brian; Freeman, Arthur J.; Tian, Rong; Luo, Xiaojuan; Lautenschlager, Eric; Challoner, A. Dorian

2008-09-01

Microsystems have become an integral part of our lives and can be found in homeland security, medical science, aerospace applications and beyond. Many critical microsystem applications are in harsh environments, in which long-term reliability needs to be guaranteed and repair is not feasible. For example, gyroscope microsystems on satellites need to function for over 20 years under severe radiation, thermal cycling, and shock loading. Hence a predictive-science-based, verified and validated computational models and algorithms to predict the performance and materials integrity of microsystems in these situations is needed. Confidence in these predictions is improved by quantifying uncertainties and approximation errors. With no full system testing and limited sub-system testings, petascale computing is certainly necessary to span both time and space scales and to reduce the uncertainty in the prediction of long-term reliability. This paper presents the necessary steps to develop predictive-science-based multiscale modeling and simulation system. The development of this system will be focused on the prediction of the long-term performance of a gyroscope microsystem. The environmental effects to be considered include radiation, thermo-mechanical cycling and shock. Since there will be many material performance issues, attention is restricted to creep resulting from thermal aging and radiation-enhanced mass diffusion, material instability due to radiation and thermo-mechanical cycling and damage and fracture due to shock. To meet these challenges, we aim to develop an integrated multiscale software analysis system that spans the length scales from the atomistic scale to the scale of the device. The proposed software system will include molecular mechanics, phase field evolution, micromechanics and continuum mechanics software, and the state-of-the-art model identification strategies where atomistic properties are calibrated by quantum calculations. We aim to predict the long-term (in excess of 20 years) integrity of the resonator, electrode base, multilayer metallic bonding pads, and vacuum seals in a prescribed mission. Although multiscale simulations are efficient in the sense that they focus the most computationally intensive models and methods on only the portions of the space time domain needed, the execution of the multiscale simulations associated with evaluating materials and device integrity for aerospace microsystems will require the application of petascale computing. A component-based software strategy will be used in the development of our massively parallel multiscale simulation system. This approach will allow us to take full advantage of existing single scale modeling components. An extensive, pervasive thrust in the software system development is verification, validation, and uncertainty quantification (UQ). Each component and the integrated software system need to be carefully verified. An UQ methodology that determines the quality of predictive information available from experimental measurements and packages the information in a form suitable for UQ at various scales needs to be developed. Experiments to validate the model at the nanoscale, microscale, and macroscale are proposed. The development of a petascale predictive-science-based multiscale modeling and simulation system will advance the field of predictive multiscale science so that it can be used to reliably analyze problems of unprecedented complexity, where limited testing resources can be adequately replaced by petascale computational power, advanced verification, validation, and UQ methodologies.

Bioenergy Development Policy and Practice Must Recognize Potential Hydrologic Impacts: Lessons from the Americas.

PubMed

Watkins, David W; de Moraes, Márcia M G Alcoforado; Asbjornsen, Heidi; Mayer, Alex S; Licata, Julian; Lopez, Jose Gutierrez; Pypker, Thomas G; Molina, Vivianna Gamez; Marques, Guilherme Fernandes; Carneiro, Ana Cristina Guimaraes; Nuñez, Hector M; Önal, Hayri; da Nobrega Germano, Bruna

2015-12-01

Large-scale bioenergy production will affect the hydrologic cycle in multiple ways, including changes in canopy interception, evapotranspiration, infiltration, and the quantity and quality of surface runoff and groundwater recharge. As such, the water footprints of bioenergy sources vary significantly by type of feedstock, soil characteristics, cultivation practices, and hydro-climatic regime. Furthermore, water management implications of bioenergy production depend on existing land use, relative water availability, and competing water uses at a watershed scale. This paper reviews previous research on the water resource impacts of bioenergy production-from plot-scale hydrologic and nutrient cycling impacts to watershed and regional scale hydro-economic systems relationships. Primary gaps in knowledge that hinder policy development for integrated management of water-bioenergy systems are highlighted. Four case studies in the Americas are analyzed to illustrate relevant spatial and temporal scales for impact assessment, along with unique aspects of biofuel production compared to other agroforestry systems, such as energy-related conflicts and tradeoffs. Based on the case studies, the potential benefits of integrated resource management are assessed, as is the need for further case-specific research.

Bioenergy Development Policy and Practice Must Recognize Potential Hydrologic Impacts: Lessons from the Americas

NASA Astrophysics Data System (ADS)

Watkins, David W.; de Moraes, Márcia M. G. Alcoforado; Asbjornsen, Heidi; Mayer, Alex S.; Licata, Julian; Lopez, Jose Gutierrez; Pypker, Thomas G.; Molina, Vivianna Gamez; Marques, Guilherme Fernandes; Carneiro, Ana Cristina Guimaraes; Nuñez, Hector M.; Önal, Hayri; da Nobrega Germano, Bruna

2015-12-01

Large-scale bioenergy production will affect the hydrologic cycle in multiple ways, including changes in canopy interception, evapotranspiration, infiltration, and the quantity and quality of surface runoff and groundwater recharge. As such, the water footprints of bioenergy sources vary significantly by type of feedstock, soil characteristics, cultivation practices, and hydro-climatic regime. Furthermore, water management implications of bioenergy production depend on existing land use, relative water availability, and competing water uses at a watershed scale. This paper reviews previous research on the water resource impacts of bioenergy production—from plot-scale hydrologic and nutrient cycling impacts to watershed and regional scale hydro-economic systems relationships. Primary gaps in knowledge that hinder policy development for integrated management of water-bioenergy systems are highlighted. Four case studies in the Americas are analyzed to illustrate relevant spatial and temporal scales for impact assessment, along with unique aspects of biofuel production compared to other agroforestry systems, such as energy-related conflicts and tradeoffs. Based on the case studies, the potential benefits of integrated resource management are assessed, as is the need for further case-specific research.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu Cenke

In this paper, we calculate the entanglement Renyi entropy of two coupled gapless systems in general spatial dimension d. The gapless systems can be either conformal field theories or Fermi liquids. We assume the two systems are coupled uniformly in an h-dimensional submanifold of the space, with 0{<=}h{<=}d. We will focus on the scaling of the Renyi entropy with the size of the system, and its scaling with the intersystem coupling constant g. Three approaches will be used for our calculation: (1) exact calculation with ground-state wave functional, (2) perturbative calculation with functional path integral, and (3) scaling argument.

Integrated Data Modeling and Simulation on the Joint Polar Satellite System Program

NASA Technical Reports Server (NTRS)

Roberts, Christopher J.; Boyce, Leslye; Smith, Gary; Li, Angela; Barrett, Larry

2012-01-01

The Joint Polar Satellite System is a modern, large-scale, complex, multi-mission aerospace program, and presents a variety of design, testing and operational challenges due to: (1) System Scope: multi-mission coordination, role, responsibility and accountability challenges stemming from porous/ill-defined system and organizational boundaries (including foreign policy interactions) (2) Degree of Concurrency: design, implementation, integration, verification and operation occurring simultaneously, at multiple scales in the system hierarchy (3) Multi-Decadal Lifecycle: technical obsolesce, reliability and sustainment concerns, including those related to organizational and industrial base. Additionally, these systems tend to become embedded in the broader societal infrastructure, resulting in new system stakeholders with perhaps different preferences (4) Barriers to Effective Communications: process and cultural issues that emerge due to geographic dispersion and as one spans boundaries including gov./contractor, NASA/Other USG, and international relationships.

Bench-scale demonstration of hot-gas desulfurization technology. Quarterly report, April 1 - June 30, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-12-31

The US Department of Energy (DOE) Morgantown Energy Technology Center (METC) is sponsoring research in advanced methods for controlling contaminants in hot coal gasifier gas (coal gas) streams of integrated gasification combined-cycle (IGCC) power systems. The programs focus on hot-gas particulate removal and desulfurization technologies that match or nearly match the temperatures and pressures of the gasifier, cleanup system, and power generator. The work seeks to eliminate the need for expensive heat recovery equipment, reduce efficiency losses due to quenching, and minimize wastewater treatment costs. The goal of this project is to continue further development of the zinc titanate desulfurizationmore » and direct sulfur recovery process (DSRP) technologies by (1) scaling up the zinc titanate reactor system; (2) developing an integrated skid-mounted zinc titanate desulfurization-DSRP reactor system; (3) testing the integrated system over an extended period with real coal-as from an operating gasifier to quantify the degradative effect, if any, of the trace contaminants present in cola gas; (4) developing an engineering database suitable for system scaleup; and (5) designing, fabricating and commissioning a larger DSRP reactor system capable of operating on a six-fold greater volume of gas than the DSRP reactor used in the bench-scale field test. The work performed during the April 1 through June 30, 1996 period is described.« less

Integrated detection of fractures and caves in carbonate fractured-vuggy reservoirs based on seismic data and well data

NASA Astrophysics Data System (ADS)

Cao, Zhanning; Li, Xiangyang; Sun, Shaohan; Liu, Qun; Deng, Guangxiao

2018-04-01

Aiming at the prediction of carbonate fractured-vuggy reservoirs, we put forward an integrated approach based on seismic and well data. We divide a carbonate fracture-cave system into four scales for study: micro-scale fracture, meso-scale fracture, macro-scale fracture and cave. Firstly, we analyze anisotropic attributes of prestack azimuth gathers based on multi-scale rock physics forward modeling. We select the frequency attenuation gradient attribute to calculate azimuth anisotropy intensity, and we constrain the result with Formation MicroScanner image data and trial production data to predict the distribution of both micro-scale and meso-scale fracture sets. Then, poststack seismic attributes, variance, curvature and ant algorithms are used to predict the distribution of macro-scale fractures. We also constrain the results with trial production data for accuracy. Next, the distribution of caves is predicted by the amplitude corresponding to the instantaneous peak frequency of the seismic imaging data. Finally, the meso-scale fracture sets, macro-scale fractures and caves are combined to obtain an integrated result. This integrated approach is applied to a real field in Tarim Basin in western China for the prediction of fracture-cave reservoirs. The results indicate that this approach can well explain the spatial distribution of carbonate reservoirs. It can solve the problem of non-uniqueness and improve fracture prediction accuracy.

Integration: the firm and the health care sector.

PubMed

Laugesen, Miriam J; France, George

2014-07-01

Integration in health care is a key goal of health reform in United States and England. Yet past efforts in the 1990s to better integrate the delivery system were of limited success. Building on work by Bevan and Janus on delivery integration, this article explores integration through the lens of economic theories of integration. Firms generally integrate to increase efficiency through economies of scale, to improve their market power, and resolve the transaction costs involved with multiple external suppliers. Using the United States and England as laboratories, we apply concepts of economic integration to understand why integration does or does not occur in health care, and whether expectations of integrating different kinds of providers (hospital, primary care) and health and social services are realistic. Current enthusiasm for a more integrated health care system expands the scope of integration to include social services in England, but retains the focus on health care in the United States. We find mixed applicability of economic theories of integration. Economies of scale have not played a significant role in stimulating integration in both countries. Managerial incentives for monopoly or oligopoly may be more compelling in the United States, since hospitals seek higher prices and more leverage over payers. In both countries the concept of transaction costs could explain the success of new payment and budgeting methods, since health care integration ultimately requires resolving transaction costs across different delivery organizations.

Scaling from instantaneous remote-sensing-based latent heat flux to daytime integrated value with the help of SiB2

NASA Astrophysics Data System (ADS)

Song, Yi; Ma, Mingguo; Li, Xin; Wang, Xufeng

2011-11-01

This research dealt with a daytime integration method with the help of Simple Biosphere Model, Version 2 (SiB2). The field observations employed in this study were obtained at the Yingke (YK) oasis super-station, which includes an Automatic Meteorological Station (AMS), an eddy covariance (EC) system and a Soil Moisture and Temperature Measuring System (SMTMS). This station is located in the Heihe River Basin, the second largest inland river basin in China. The remotely sensed data and field observations employed in this study were derived from Watershed Allied Telemetry Experimental Research (WATER). Daily variations of EF in temporal and spatial scale would be detected by using SiB2. An instantaneous midday EF was calculated based on a remote-sensing-based estimation of surface energy budget. The invariance of daytime EF was examined using the instantaneous midday EF calculated from a remote-sensing-based estimation. The integration was carried out using the constant EF method in the intervals with a steady EF. Intervals with an inconsistent EF were picked up and ET in these intervals was integrated separately. The truth validation of land Surface ET at satellite pixel scale was carried out using the measurement of eddy covariance (EC) system.

Lunar Simulants, Analogues, and Standards: Needs and Realities for Mission Technologies Development

NASA Technical Reports Server (NTRS)

Sibille, Laurent

2013-01-01

Integration of In-Situ Resource Utilization (ISRU) capabilities into missions present both challenges as well as benefits for future missions to the Moon and Mars. However, since ISRU systems and capabilities have not flown, mission planners have been hesitant to include ISRU capabilities in mission critical roles, thereby significantly reducing the benefits that ISRU can provide in mission mass and cost reductions. For ISRU systems to provide products and services to 'customers' such as life support, propulsion, and power systems, close development of requirements, hardware, and operations between ISRU and these systems are required. To address these development and incorporation challenges, NASA and csA initiated a series of analog field test demonstrations at sites in Hawaii. Two tests completed in November of 2008 and February of 2010 have demonstrate all the critical steps in operating ISRU systems on the lunar surface at relevant mission scales as well as integration with power and propulsion systems. The third field test planned for July 2012 will demonstrate that a mission to the lunar poles to locate and characterize ice and other volatiles is possible in a highly integrated mission with multiple space agencies. These analog field tests have shown that not only are ISRU systems feasible at relevant mission scales, that they can be successfully integrated into mission architectures.

Design and Manufacture of Structurally Efficient Tapered Struts

NASA Technical Reports Server (NTRS)

Brewster, Jebediah W.

2009-01-01

Composite materials offer the potential of weight savings for numerous spacecraft and aircraft applications. A composite strut is just one integral part of the node-to-node system and the optimization of the shut and node assembly is needed to take full advantage of the benefit of composites materials. Lockheed Martin designed and manufactured a very light weight one piece composite tapered strut that is fully representative of a full scale flight article. In addition, the team designed and built a prototype of the node and end fitting system that will effectively integrate and work with the full scale flight articles.

Hierarchical hybrid control of manipulators: Artificial intelligence in large scale integrated circuits

NASA Technical Reports Server (NTRS)

Greene, P. H.

1972-01-01

Both in practical engineering and in control of muscular systems, low level subsystems automatically provide crude approximations to the proper response. Through low level tuning of these approximations, the proper response variant can emerge from standardized high level commands. Such systems are expressly suited to emerging large scale integrated circuit technology. A computer, using symbolic descriptions of subsystem responses, can select and shape responses of low level digital or analog microcircuits. A mathematical theory that reveals significant informational units in this style of control and software for realizing such information structures are formulated.

Differential settlement of a geosynthetic reinforced soil abutment : full-scale investigation.

DOT National Transportation Integrated Search

2015-05-01

The Geosynthetic Reinforced Soil Integrated Bridge System (GRS-IBS) uses alternating layers of closely spaced : geosynthetic reinforcement and well-compacted granular fill to support the bridge superstructure and form an integrated roadway : approach...

Monolithic silicon-photonic platforms in state-of-the-art CMOS SOI processes [Invited].

PubMed

Stojanović, Vladimir; Ram, Rajeev J; Popović, Milos; Lin, Sen; Moazeni, Sajjad; Wade, Mark; Sun, Chen; Alloatti, Luca; Atabaki, Amir; Pavanello, Fabio; Mehta, Nandish; Bhargava, Pavan

2018-05-14

Integrating photonics with advanced electronics leverages transistor performance, process fidelity and package integration, to enable a new class of systems-on-a-chip for a variety of applications ranging from computing and communications to sensing and imaging. Monolithic silicon photonics is a promising solution to meet the energy efficiency, sensitivity, and cost requirements of these applications. In this review paper, we take a comprehensive view of the performance of the silicon-photonic technologies developed to date for photonic interconnect applications. We also present the latest performance and results of our "zero-change" silicon photonics platforms in 45 nm and 32 nm SOI CMOS. The results indicate that the 45 nm and 32 nm processes provide a "sweet-spot" for adding photonic capability and enhancing integrated system applications beyond the Moore-scaling, while being able to offload major communication tasks from more deeply-scaled compute and memory chips without complicated 3D integration approaches.

Micro-scale heat-exchangers for Joule-Thomson cooling.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gross, Andrew John

2014-01-01

This project focused on developing a micro-scale counter flow heat exchangers for Joule-Thomson cooling with the potential for both chip and wafer scale integration. This project is differentiated from previous work by focusing on planar, thin film micromachining instead of bulk materials. A process will be developed for fabricating all the devices mentioned above, allowing for highly integrated micro heat exchangers. The use of thin film dielectrics provides thermal isolation, increasing efficiency of the coolers compared to designs based on bulk materials, and it will allow for wafer-scale fabrication and integration. The process is intended to implement a CFHX asmore » part of a Joule-Thomson cooling system for applications with heat loads less than 1mW. This report presents simulation results and investigation of a fabrication process for such devices.« less

Beyond CMOS: heterogeneous integration of III–V devices, RF MEMS and other dissimilar materials/devices with Si CMOS to create intelligent microsystems

PubMed Central

Kazior, Thomas E.

2014-01-01

Advances in silicon technology continue to revolutionize micro-/nano-electronics. However, Si cannot do everything, and devices/components based on other materials systems are required. What is the best way to integrate these dissimilar materials and to enhance the capabilities of Si, thereby continuing the micro-/nano-electronics revolution? In this paper, I review different approaches to heterogeneously integrate dissimilar materials with Si complementary metal oxide semiconductor (CMOS) technology. In particular, I summarize results on the successful integration of III–V electronic devices (InP heterojunction bipolar transistors (HBTs) and GaN high-electron-mobility transistors (HEMTs)) with Si CMOS on a common silicon-based wafer using an integration/fabrication process similar to a SiGe BiCMOS process (BiCMOS integrates bipolar junction and CMOS transistors). Our III–V BiCMOS process has been scaled to 200 mm diameter wafers for integration with scaled CMOS and used to fabricate radio-frequency (RF) and mixed signals circuits with on-chip digital control/calibration. I also show that RF microelectromechanical systems (MEMS) can be integrated onto this platform to create tunable or reconfigurable circuits. Thus, heterogeneous integration of III–V devices, MEMS and other dissimilar materials with Si CMOS enables a new class of high-performance integrated circuits that enhance the capabilities of existing systems, enable new circuit architectures and facilitate the continued proliferation of low-cost micro-/nano-electronics for a wide range of applications. PMID:24567473

Beyond CMOS: heterogeneous integration of III-V devices, RF MEMS and other dissimilar materials/devices with Si CMOS to create intelligent microsystems.

PubMed

Kazior, Thomas E

2014-03-28

Advances in silicon technology continue to revolutionize micro-/nano-electronics. However, Si cannot do everything, and devices/components based on other materials systems are required. What is the best way to integrate these dissimilar materials and to enhance the capabilities of Si, thereby continuing the micro-/nano-electronics revolution? In this paper, I review different approaches to heterogeneously integrate dissimilar materials with Si complementary metal oxide semiconductor (CMOS) technology. In particular, I summarize results on the successful integration of III-V electronic devices (InP heterojunction bipolar transistors (HBTs) and GaN high-electron-mobility transistors (HEMTs)) with Si CMOS on a common silicon-based wafer using an integration/fabrication process similar to a SiGe BiCMOS process (BiCMOS integrates bipolar junction and CMOS transistors). Our III-V BiCMOS process has been scaled to 200 mm diameter wafers for integration with scaled CMOS and used to fabricate radio-frequency (RF) and mixed signals circuits with on-chip digital control/calibration. I also show that RF microelectromechanical systems (MEMS) can be integrated onto this platform to create tunable or reconfigurable circuits. Thus, heterogeneous integration of III-V devices, MEMS and other dissimilar materials with Si CMOS enables a new class of high-performance integrated circuits that enhance the capabilities of existing systems, enable new circuit architectures and facilitate the continued proliferation of low-cost micro-/nano-electronics for a wide range of applications.

Chromatin Landscapes of Retroviral and Transposon Integration Profiles

PubMed Central

Badhai, Jitendra; Rust, Alistair G.; Rad, Roland; Hilkens, John; Berns, Anton; van Lohuizen, Maarten; Wessels, Lodewyk F. A.; de Ridder, Jeroen

2014-01-01

The ability of retroviruses and transposons to insert their genetic material into host DNA makes them widely used tools in molecular biology, cancer research and gene therapy. However, these systems have biases that may strongly affect research outcomes. To address this issue, we generated very large datasets consisting of to unselected integrations in the mouse genome for the Sleeping Beauty (SB) and piggyBac (PB) transposons, and the Mouse Mammary Tumor Virus (MMTV). We analyzed (epi)genomic features to generate bias maps at both local and genome-wide scales. MMTV showed a remarkably uniform distribution of integrations across the genome. More distinct preferences were observed for the two transposons, with PB showing remarkable resemblance to bias profiles of the Murine Leukemia Virus. Furthermore, we present a model where target site selection is directed at multiple scales. At a large scale, target site selection is similar across systems, and defined by domain-oriented features, namely expression of proximal genes, proximity to CpG islands and to genic features, chromatin compaction and replication timing. Notable differences between the systems are mainly observed at smaller scales, and are directed by a diverse range of features. To study the effect of these biases on integration sites occupied under selective pressure, we turned to insertional mutagenesis (IM) screens. In IM screens, putative cancer genes are identified by finding frequently targeted genomic regions, or Common Integration Sites (CISs). Within three recently completed IM screens, we identified 7%–33% putative false positive CISs, which are likely not the result of the oncogenic selection process. Moreover, results indicate that PB, compared to SB, is more suited to tag oncogenes. PMID:24721906

Organic Coasts? Regulatory Challenges of Certifying Integrated Shrimp-Mangrove Production Systems in Vietnam

ERIC Educational Resources Information Center

Ha, Tran Thi Thu; Bush, Simon R.; Mol, Arthur P. J.; van Dijk, Han

2012-01-01

The Vietnamese government aims to expand the scale of Naturland certified organic production in integrated shrimp-mangrove farming systems across the coast of Ca Mau province by 2015. In doing so the division between public and private regulation has become blurred. We analyze the government's goal by examining the regulatory challenges of using…

Energy Systems Integration News | Energy Systems Integration Facility |

Science.gov Websites

photovoltaic (PV) energy for its power. PV inverter hardware-in the loop testing was conducted at NREL's Energy -scale power-hardware-in-the-loop testing at the ESIF, which allows researchers and manufacturers to test field. In addition, the CGI provides hardware-in-the-loop capability combined with NWTC dynamometers

Energy Systems Integration Facility to Transform U.S. Energy Infrastructure

Science.gov Websites

operations center. Fully integrated with hardware-in-the-loop at power capabilities, an experimental hardware- and systems-in-the-loop capability. Hardware-in-the-Loop at Power ESIF Snapshot Cost : $135M 2013 Hardware-in-the-loop simulation is not a new concept, but adding megawatt-scale power takes

The Department of Defense Very High Speed Integrated Circuit (VHSIC) Technology Availability Program Plan for the Committees on Armed Services United States Congress.

DTIC Science & Technology

1986-06-30

features of computer aided design systems and statistical quality control procedures that are generic to chip sets and processes. RADIATION HARDNESS -The...System PSP Programmable Signal Processor SSI Small Scale Integration ." TOW Tube Launched, Optically Tracked, Wire Guided TTL Transistor Transitor Logic

A Case Study in an Integrated Development and Problem Solving Environment

ERIC Educational Resources Information Center

Deek, Fadi P.; McHugh, James A.

2003-01-01

This article describes an integrated problem solving and program development environment, illustrating the application of the system with a detailed case study of a small-scale programming problem. The system, which is based on an explicit cognitive model, is intended to guide the novice programmer through the stages of problem solving and program…

Integrative Systems Biology for Data Driven Knowledge Discovery

PubMed Central

Greene, Casey S.; Troyanskaya, Olga G.

2015-01-01

Integrative systems biology is an approach that brings together diverse high throughput experiments and databases to gain new insights into biological processes or systems at molecular through physiological levels. These approaches rely on diverse high-throughput experimental techniques that generate heterogeneous data by assaying varying aspects of complex biological processes. Computational approaches are necessary to provide an integrative view of these experimental results and enable data-driven knowledge discovery. Hypotheses generated from these approaches can direct definitive molecular experiments in a cost effective manner. Using integrative systems biology approaches, we can leverage existing biological knowledge and large-scale data to improve our understanding of yet unknown components of a system of interest and how its malfunction leads to disease. PMID:21044756

VLSI technology for smaller, cheaper, faster return link systems

NASA Technical Reports Server (NTRS)

Nanzetta, Kathy; Ghuman, Parminder; Bennett, Toby; Solomon, Jeff; Dowling, Jason; Welling, John

1994-01-01

Very Large Scale Integration (VLSI) Application-specific Integrated Circuit (ASIC) technology has enabled substantially smaller, cheaper, and more capable telemetry data systems. However, the rapid growth in available ASIC fabrication densities has far outpaced the application of this technology to telemetry systems. Available densities have grown by well over an order magnitude since NASA's Goddard Space Flight Center (GSFC) first began developing ASIC's for ground telemetry systems in 1985. To take advantage of these higher integration levels, a new generation of ASIC's for return link telemetry processing is under development. These new submicron devices are designed to further reduce the cost and size of NASA return link processing systems while improving performance. This paper describes these highly integrated processing components.

The Computing and Data Grid Approach: Infrastructure for Distributed Science Applications

NASA Technical Reports Server (NTRS)

Johnston, William E.

2002-01-01

With the advent of Grids - infrastructure for using and managing widely distributed computing and data resources in the science environment - there is now an opportunity to provide a standard, large-scale, computing, data, instrument, and collaboration environment for science that spans many different projects and provides the required infrastructure and services in a relatively uniform and supportable way. Grid technology has evolved over the past several years to provide the services and infrastructure needed for building 'virtual' systems and organizations. We argue that Grid technology provides an excellent basis for the creation of the integrated environments that can combine the resources needed to support the large- scale science projects located at multiple laboratories and universities. We present some science case studies that indicate that a paradigm shift in the process of science will come about as a result of Grids providing transparent and secure access to advanced and integrated information and technologies infrastructure: powerful computing systems, large-scale data archives, scientific instruments, and collaboration tools. These changes will be in the form of services that can be integrated with the user's work environment, and that enable uniform and highly capable access to these computers, data, and instruments, regardless of the location or exact nature of these resources. These services will integrate transient-use resources like computing systems, scientific instruments, and data caches (e.g., as they are needed to perform a simulation or analyze data from a single experiment); persistent-use resources. such as databases, data catalogues, and archives, and; collaborators, whose involvement will continue for the lifetime of a project or longer. While we largely address large-scale science in this paper, Grids, particularly when combined with Web Services, will address a broad spectrum of science scenarios. both large and small scale.

HPC AND GRID COMPUTING FOR INTEGRATIVE BIOMEDICAL RESEARCH

PubMed Central

Kurc, Tahsin; Hastings, Shannon; Kumar, Vijay; Langella, Stephen; Sharma, Ashish; Pan, Tony; Oster, Scott; Ervin, David; Permar, Justin; Narayanan, Sivaramakrishnan; Gil, Yolanda; Deelman, Ewa; Hall, Mary; Saltz, Joel

2010-01-01

Integrative biomedical research projects query, analyze, and integrate many different data types and make use of datasets obtained from measurements or simulations of structure and function at multiple biological scales. With the increasing availability of high-throughput and high-resolution instruments, the integrative biomedical research imposes many challenging requirements on software middleware systems. In this paper, we look at some of these requirements using example research pattern templates. We then discuss how middleware systems, which incorporate Grid and high-performance computing, could be employed to address the requirements. PMID:20107625

HIV scale-up in Mozambique: Exceptionalism, normalisation and global health

PubMed Central

Høg, Erling

2014-01-01

The large-scale introduction of HIV and AIDS services in Mozambique from 2000 onwards occurred in the context of deep political commitment to sovereign nation-building and an important transition in the nation's health system. Simultaneously, the international community encountered a willing state partner that recognised the need to take action against the HIV epidemic. This article examines two critical policy shifts: sustained international funding and public health system integration (the move from parallel to integrated HIV services). The Mozambican government struggles to support its national health system against privatisation, NGO competition and internal brain drain. This is a sovereignty issue. However, the dominant discourse on self-determination shows a contradictory twist: it is part of the political rhetoric to keep the sovereignty discourse alive, while the real challenge is coordination, not partnerships. Nevertheless, we need more anthropological studies to understand the political implications of global health funding and governance. Other studies need to examine the consequences of public health system integration for the quality of access to health care. PMID:24499102

A long time span relativistic precession model of the Earth

NASA Astrophysics Data System (ADS)

Tang, Kai; Soffel, Michael H.; Tao, Jin-He; Han, Wen-Biao; Tang, Zheng-Hong

2015-04-01

A numerical solution to the Earth's precession in a relativistic framework for a long time span is presented here. We obtain the motion of the solar system in the Barycentric Celestial Reference System by numerical integration with a symplectic integrator. Special Newtonian corrections accounting for tidal dissipation are included in the force model. The part representing Earth's rotation is calculated in the Geocentric Celestial Reference System by integrating the post-Newtonian equations of motion published by Klioner et al. All the main relativistic effects are included following Klioner et al. In particular, we consider several relativistic reference systems with corresponding time scales, scaled constants and parameters. Approximate expressions for Earth's precession in the interval ±1 Myr around J2000.0 are provided. In the interval ±2000 years around J2000.0, the difference compared to the P03 precession theory is only several arcseconds and the results are consistent with other long-term precession theories. Supported by the National Natural Science Foundation of China.

HIV scale-up in Mozambique: exceptionalism, normalisation and global health.

PubMed

Høg, Erling

2014-01-01

The large-scale introduction of HIV and AIDS services in Mozambique from 2000 onwards occurred in the context of deep political commitment to sovereign nation-building and an important transition in the nation's health system. Simultaneously, the international community encountered a willing state partner that recognised the need to take action against the HIV epidemic. This article examines two critical policy shifts: sustained international funding and public health system integration (the move from parallel to integrated HIV services). The Mozambican government struggles to support its national health system against privatisation, NGO competition and internal brain drain. This is a sovereignty issue. However, the dominant discourse on self-determination shows a contradictory twist: it is part of the political rhetoric to keep the sovereignty discourse alive, while the real challenge is coordination, not partnerships. Nevertheless, we need more anthropological studies to understand the political implications of global health funding and governance. Other studies need to examine the consequences of public health system integration for the quality of access to health care.

Integrated network analysis and effective tools in plant systems biology

PubMed Central

Fukushima, Atsushi; Kanaya, Shigehiko; Nishida, Kozo

2014-01-01

One of the ultimate goals in plant systems biology is to elucidate the genotype-phenotype relationship in plant cellular systems. Integrated network analysis that combines omics data with mathematical models has received particular attention. Here we focus on the latest cutting-edge computational advances that facilitate their combination. We highlight (1) network visualization tools, (2) pathway analyses, (3) genome-scale metabolic reconstruction, and (4) the integration of high-throughput experimental data and mathematical models. Multi-omics data that contain the genome, transcriptome, proteome, and metabolome and mathematical models are expected to integrate and expand our knowledge of complex plant metabolisms. PMID:25408696

Differential settlement of a geosynthetic reinforced soil abutment : full-scale investigation : summary report.

DOT National Transportation Integrated Search

2015-05-01

The Geosynthetic Reinforced Soil Integrated Bridge System (GRS-IBS) uses alternating layers of closely spaced : geosynthetic reinforcement and well-compacted granular fill to support the bridge superstructure and form an integrated roadway : approach...

Structured approaches to large-scale systems: Variational integrators for interconnected Lagrange-Dirac systems and structured model reduction on Lie groups

NASA Astrophysics Data System (ADS)

Parks, Helen Frances

This dissertation presents two projects related to the structured integration of large-scale mechanical systems. Structured integration uses the considerable differential geometric structure inherent in mechanical motion to inform the design of numerical integration schemes. This process improves the qualitative properties of simulations and becomes especially valuable as a measure of accuracy over long time simulations in which traditional Gronwall accuracy estimates lose their meaning. Often, structured integration schemes replicate continuous symmetries and their associated conservation laws at the discrete level. Such is the case for variational integrators, which discretely replicate the process of deriving equations of motion from variational principles. This results in the conservation of momenta associated to symmetries in the discrete system and conservation of a symplectic form when applicable. In the case of Lagrange-Dirac systems, variational integrators preserve a discrete analogue of the Dirac structure preserved in the continuous flow. In the first project of this thesis, we extend Dirac variational integrators to accommodate interconnected systems. We hope this work will find use in the fields of control, where a controlled system can be thought of as a "plant" system joined to its controller, and in the approach of very large systems, where modular modeling may prove easier than monolithically modeling the entire system. The second project of the thesis considers a different approach to large systems. Given a detailed model of the full system, can we reduce it to a more computationally efficient model without losing essential geometric structures in the system? Asked without the reference to structure, this is the essential question of the field of model reduction. The answer there has been a resounding yes, with Principal Orthogonal Decomposition (POD) with snapshots rising as one of the most successful methods. Our project builds on previous work to extend POD to structured settings. In particular, we consider systems evolving on Lie groups and make use of canonical coordinates in the reduction process. We see considerable improvement in the accuracy of the reduced model over the usual structure-agnostic POD approach.

Unlocking Flexibility: Integrated Optimization and Control of Multienergy Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dall'Anese, Emiliano; Mancarella, Pierluigi; Monti, Antonello

Electricity, natural gas, water, and dis trict heating/cooling systems are predominantly planned and operated independently. However, it is increasingly recognized that integrated optimization and control of such systems at multiple spatiotemporal scales can bring significant socioeconomic, operational efficiency, and environmental benefits. Accordingly, the concept of the multi-energy system is gaining considerable attention, with the overarching objectives of 1) uncovering fundamental gains (and potential drawbacks) that emerge from the integrated operation of multiple systems and 2) developing holistic yet computationally affordable optimization and control methods that maximize operational benefits, while 3) acknowledging intrinsic interdependencies and quality-of-service requirements for each provider.

Topics in programmable automation. [for materials handling, inspection, and assembly

NASA Technical Reports Server (NTRS)

Rosen, C. A.

1975-01-01

Topics explored in the development of integrated programmable automation systems include: numerically controlled and computer controlled machining; machine intelligence and the emulation of human-like capabilities; large scale semiconductor integration technology applications; and sensor technology for asynchronous local computation without burdening the executive minicomputer which controls the whole system. The role and development of training aids, and the potential application of these aids to augmented teleoperator systems are discussed.

Robust decentralized hybrid adaptive output feedback fuzzy control for a class of large-scale MIMO nonlinear systems and its application to AHS.

PubMed

Huang, Yi-Shao; Liu, Wel-Ping; Wu, Min; Wang, Zheng-Wu

2014-09-01

This paper presents a novel observer-based decentralized hybrid adaptive fuzzy control scheme for a class of large-scale continuous-time multiple-input multiple-output (MIMO) uncertain nonlinear systems whose state variables are unmeasurable. The scheme integrates fuzzy logic systems, state observers, and strictly positive real conditions to deal with three issues in the control of a large-scale MIMO uncertain nonlinear system: algorithm design, controller singularity, and transient response. Then, the design of the hybrid adaptive fuzzy controller is extended to address a general large-scale uncertain nonlinear system. It is shown that the resultant closed-loop large-scale system keeps asymptotically stable and the tracking error converges to zero. The better characteristics of our scheme are demonstrated by simulations. Copyright © 2014. Published by Elsevier Ltd.

A Multi-Scale Integrated Approach to Representing Watershed Systems: Significance and Challenges

NASA Astrophysics Data System (ADS)

Kim, J.; Ivanov, V. Y.; Katopodes, N.

2013-12-01

A range of processes associated with supplying services and goods to human society originate at the watershed level. Predicting watershed response to forcing conditions has been of high interest to many practical societal problems, however, remains challenging due to two significant properties of the watershed systems, i.e., connectivity and non-linearity. Connectivity implies that disturbances arising at any larger scale will necessarily propagate and affect local-scale processes; their local effects consequently influence other processes, and often convey nonlinear relationships. Physically-based, process-scale modeling is needed to approach the understanding and proper assessment of non-linear effects between the watershed processes. We have developed an integrated model simulating hydrological processes, flow dynamics, erosion and sediment transport, tRIBS-OFM-HRM (Triangulated irregular network - based Real time Integrated Basin Simulator-Overland Flow Model-Hairsine and Rose Model). This coupled model offers the advantage of exploring the hydrological effects of watershed physical factors such as topography, vegetation, and soil, as well as their feedback mechanisms. Several examples investigating the effects of vegetation on flow movement, the role of soil's substrate on sediment dynamics, and the driving role of topography on morphological processes are illustrated. We show how this comprehensive modeling tool can help understand interconnections and nonlinearities of the physical system, e.g., how vegetation affects hydraulic resistance depending on slope, vegetation cover fraction, discharge, and bed roughness condition; how the soil's substrate condition impacts erosion processes with an non-unique characteristic at the scale of a zero-order catchment; and how topographic changes affect spatial variations of morphologic variables. Due to feedback and compensatory nature of mechanisms operating in different watershed compartments, our conclusion is that a key to representing watershed systems lies in an integrated, interdisciplinary approach, whereby a physically-based model is used for assessments/evaluations associated with future changes in landuse, climate, and ecosystems.

A regional scale modeling framework combining biogeochemical model with life cycle and economic analysis for integrated assessment of cropping systems.

PubMed

Tabatabaie, Seyed Mohammad Hossein; Bolte, John P; Murthy, Ganti S

2018-06-01

The goal of this study was to integrate a crop model, DNDC (DeNitrification-DeComposition), with life cycle assessment (LCA) and economic analysis models using a GIS-based integrated platform, ENVISION. The integrated model enables LCA practitioners to conduct integrated economic analysis and LCA on a regional scale while capturing the variability of soil emissions due to variation in regional factors during production of crops and biofuel feedstocks. In order to evaluate the integrated model, the corn-soybean cropping system in Eagle Creek Watershed, Indiana was studied and the integrated model was used to first model the soil emissions and then conduct the LCA as well as economic analysis. The results showed that the variation in soil emissions due to variation in weather is high causing some locations to be carbon sink in some years and source of CO 2 in other years. In order to test the model under different scenarios, two tillage scenarios were defined: 1) conventional tillage (CT) and 2) no tillage (NT) and analyzed with the model. The overall GHG emissions for the corn-soybean cropping system was simulated and results showed that the NT scenario resulted in lower soil GHG emissions compared to CT scenario. Moreover, global warming potential (GWP) of corn ethanol from well to pump varied between 57 and 92gCO 2 -eq./MJ while GWP under the NT system was lower than that of the CT system. The cost break-even point was calculated as $3612.5/ha in a two year corn-soybean cropping system and the results showed that under low and medium prices for corn and soybean most of the farms did not meet the break-even point. Copyright © 2017 Elsevier B.V. All rights reserved.

Decision-support for Digester-Algae IntegRation for Improved Environmental and Economic Sustainability (DAIRIEES)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guillen, Donna Post

Manure management is a major concern for dairy farms, as manure emits significant quantities of greenhouse gases and contains concentrated nutrients, especially nitrogen and phosphorus. Current manure management practices consist of spreading minimally processed manure on agricultural fields, which releases greenhouse gases directly to the atmosphere and often leads to nutrient overloading on fields and runoff to surface and groundwater. A novel manure treatment system has been proposed that mitigates many of the current environmental concerns and creates value added products from the manure including bioplastics, electricity, fertilizer, and animal bedding. DAIRIEES, an Excel based model, allows users to entermore » characteristics about a dairy farm’s manure, manure management plan, and regional market. Based on these inputs, the five main processes of the integrated system—fermenter, anaerobic digester, bioplastics reactor, algae cultivation, and hydrothermal liquefaction or fast pyrolysis system—are analyzed in detail using data from laboratory scale experiments supplemented by information on full-scale processes from the literature. The model can be used to estimate performance of the integrated manure treatment system, including: 1) carbon and nutrient sequestration, 2) quantities and market value of end products, and 3) the system’s overall economic viability. The DAIRIEES model outlines the major economic considerations for construction and operation of a full scale integrated treatment system. This information can be used to inform a more detailed pro forma analysis of the deployed system.« less

Forest Ecosystem Analysis Using a GIS

Treesearch

S.G. McNulty; W.T. Swank

1996-01-01

Forest ecosystem studies have expanded spatially in recent years to address large scale environmental issues. We are using a geographic information system (GIS) to understand and integrate forest processes at landscape to regional spatial scales. This paper presents three diverse research studies using a GIS. First, we used a GIS to develop a landscape scale model to...

Dimensionality and integrals of motion of the Trappist-1 planetary system

NASA Astrophysics Data System (ADS)

Floß, Johannes; Rein, Hanno; Brumer, Paul

2018-04-01

The number of isolating integrals of motion of the Trappist-1 system - a late M-dwarf orbited by seven Earth-sized planets - was determined numerically, using an adapted version of the correlation dimension method. It was found that over the investigated time-scales of up to 20 000 years the number of isolating integrals of motion is the same as one would find for a system of seven non-interacting planets - despite the fact that the planets in the Trappist-1 system are strongly interacting. Considering perturbed versions of the Trappist-1 system shows that the system may occupy an atypical part of phase-space with high stability. These findings are consistent with earlier studies.

Develop and test fuel cell powered on-site integrated total energy system. Phase 3: Full-scale power plant development

NASA Technical Reports Server (NTRS)

Kaufman, A.

1981-01-01

An integrated 5 kW power system based upon methanol fuel and a phosphoric acid fuel cell operating at about 473 K is described. Description includes test results of advanced fuel cell catalysts, a semiautomatic acid replenishment system and a completed 5 kW methanol/system reformer. The results of a preliminary system test on a reformer/stack/inverter combination are reported. An initial design for a 25 kW stack is presented. Experimental plans are outlined for data acquisition necessary for design of a 50 kW methanol/steam reformer. Activities related to complete mathematical modelling of the integrated power system, including wasteheat utilization, are described.

Dimensionality and integrals of motion of the Trappist-1 planetary system

NASA Astrophysics Data System (ADS)

Floß, Johannes; Rein, Hanno; Brumer, Paul

2018-07-01

The number of isolating integrals of motion of the Trappist-1 system - a late M-dwarf orbited by seven Earth-sized planets - was determined numerically, using an adapted version of the correlation dimension method. It was found that over the investigated time-scales of up to 20 000 yr the number of isolating integrals of motion is the same as one would find for a system of seven non-interacting planets - despite the fact that the planets in the Trappist-1 system are strongly interacting. Considering perturbed versions of the Trappist-1 system shows that the system may occupy an atypical part of phase-space with high stability. These findings are consistent with earlier studies.

Wafer-scale integrated micro-supercapacitors on an ultrathin and highly flexible biomedical platform.

PubMed

Maeng, Jimin; Meng, Chuizhou; Irazoqui, Pedro P

2015-02-01

We present wafer-scale integrated micro-supercapacitors on an ultrathin and highly flexible parylene platform, as progress toward sustainably powering biomedical microsystems suitable for implantable and wearable applications. All-solid-state, low-profile (<30 μm), and high-density (up to ~500 μF/mm(2)) micro-supercapacitors are formed on an ultrathin (~20 μm) freestanding parylene film by a wafer-scale parylene packaging process in combination with a polyaniline (PANI) nanowire growth technique assisted by surface plasma treatment. These micro-supercapacitors are highly flexible and shown to be resilient toward flexural stress. Further, direct integration of micro-supercapacitors into a radio frequency (RF) rectifying circuit is achieved on a single parylene platform, yielding a complete RF energy harvesting microsystem. The system discharging rate is shown to improve by ~17 times in the presence of the integrated micro-supercapacitors. This result suggests that the integrated micro-supercapacitor technology described herein is a promising strategy for sustainably powering biomedical microsystems dedicated to implantable and wearable applications.

Avionic Data Bus Integration Technology

DTIC Science & Technology

1991-12-01

address the hardware-software interaction between a digital data bus and an avionic system. Very Large Scale Integration (VLSI) ICs and multiversion ...the SCP. In 1984, the Sperry Corporation developed a fault tolerant system which employed multiversion programming, voting, and monitoring for error... MULTIVERSION PROGRAMMING. N-version programming. 226 N-VERSION PROGRAMMING. The independent coding of a number, N, of redundant computer programs that

The Emerging Role of the Data Base Manager. Report No. R-1253-PR.

ERIC Educational Resources Information Center

Sawtelle, Thomas K.

The Air Force Logistics Command (AFLC) is revising and enhancing its data-processing capabilities with the development of a large-scale, multi-site, on-line, integrated data base information system known as the Advanced Logistics System (ALS). A data integrity program is to be built around a Data Base Manager (DBM), an individual or a group of…

Wafer-scale pixelated detector system

DOEpatents

Fahim, Farah; Deptuch, Grzegorz; Zimmerman, Tom

2017-10-17

A large area, gapless, detection system comprises at least one sensor; an interposer operably connected to the at least one sensor; and at least one application specific integrated circuit operably connected to the sensor via the interposer wherein the detection system provides high dynamic range while maintaining small pixel area and low power dissipation. Thereby the invention provides methods and systems for a wafer-scale gapless and seamless detector systems with small pixels, which have both high dynamic range and low power dissipation.

Multiscale information modelling for heart morphogenesis

NASA Astrophysics Data System (ADS)

Abdulla, T.; Imms, R.; Schleich, J. M.; Summers, R.

2010-07-01

Science is made feasible by the adoption of common systems of units. As research has become more data intensive, especially in the biomedical domain, it requires the adoption of a common system of information models, to make explicit the relationship between one set of data and another, regardless of format. This is being realised through the OBO Foundry to develop a suite of reference ontologies, and NCBO Bioportal to provide services to integrate biomedical resources and functionality to visualise and create mappings between ontology terms. Biomedical experts tend to be focused at one level of spatial scale, be it biochemistry, cell biology, or anatomy. Likewise, the ontologies they use tend to be focused at a particular level of scale. There is increasing interest in a multiscale systems approach, which attempts to integrate between different levels of scale to gain understanding of emergent effects. This is a return to physiological medicine with a computational emphasis, exemplified by the worldwide Physiome initiative, and the European Union funded Network of Excellence in the Virtual Physiological Human. However, little work has been done on how information modelling itself may be tailored to a multiscale systems approach. We demonstrate how this can be done for the complex process of heart morphogenesis, which requires multiscale understanding in both time and spatial domains. Such an effort enables the integration of multiscale metrology.

Multi -omics and metabolic modelling pipelines: challenges and tools for systems microbiology.

PubMed

Fondi, Marco; Liò, Pietro

2015-02-01

Integrated -omics approaches are quickly spreading across microbiology research labs, leading to (i) the possibility of detecting previously hidden features of microbial cells like multi-scale spatial organization and (ii) tracing molecular components across multiple cellular functional states. This promises to reduce the knowledge gap between genotype and phenotype and poses new challenges for computational microbiologists. We underline how the capability to unravel the complexity of microbial life will strongly depend on the integration of the huge and diverse amount of information that can be derived today from -omics experiments. In this work, we present opportunities and challenges of multi -omics data integration in current systems biology pipelines. We here discuss which layers of biological information are important for biotechnological and clinical purposes, with a special focus on bacterial metabolism and modelling procedures. A general review of the most recent computational tools for performing large-scale datasets integration is also presented, together with a possible framework to guide the design of systems biology experiments by microbiologists. Copyright © 2015. Published by Elsevier GmbH.

‘Integrative Physiology 2.0’: integration of systems biology into physiology and its application to cardiovascular homeostasis

PubMed Central

Kuster, Diederik W D; Merkus, Daphne; van der Velden, Jolanda; Verhoeven, Adrie J M; Duncker, Dirk J

2011-01-01

Since the completion of the Human Genome Project and the advent of the large scaled unbiased ‘-omics’ techniques, the field of systems biology has emerged. Systems biology aims to move away from the traditional reductionist molecular approach, which focused on understanding the role of single genes or proteins, towards a more holistic approach by studying networks and interactions between individual components of networks. From a conceptual standpoint, systems biology elicits a ‘back to the future’ experience for any integrative physiologist. However, many of the new techniques and modalities employed by systems biologists yield tremendous potential for integrative physiologists to expand their tool arsenal to (quantitatively) study complex biological processes, such as cardiac remodelling and heart failure, in a truly holistic fashion. We therefore advocate that systems biology should not become/stay a separate discipline with ‘-omics’ as its playing field, but should be integrated into physiology to create ‘Integrative Physiology 2.0’. PMID:21224228

Ceramic Integration Technologies for Advanced Energy Systems: Critical Needs, Technical Challenges, and Opportunities

NASA Technical Reports Server (NTRS)

Singh, Mrityunjay

2010-01-01

Advanced ceramic integration technologies dramatically impact the energy landscape due to wide scale application of ceramics in all aspects of alternative energy production, storage, distribution, conservation, and efficiency. Examples include fuel cells, thermoelectrics, photovoltaics, gas turbine propulsion systems, distribution and transmission systems based on superconductors, nuclear power generation and waste disposal. Ceramic integration technologies play a key role in fabrication and manufacturing of large and complex shaped parts with multifunctional properties. However, the development of robust and reliable integrated systems with optimum performance requires the understanding of many thermochemical and thermomechanical factors, particularly for high temperature applications. In this presentation, various needs, challenges, and opportunities in design, fabrication, and testing of integrated similar (ceramic ceramic) and dissimilar (ceramic metal) material www.nasa.gov 45 ceramic-ceramic-systems have been discussed. Experimental results for bonding and integration of SiC based Micro-Electro-Mechanical-Systems (MEMS) LDI fuel injector and advanced ceramics and composites for gas turbine applications are presented.

Atmospheric Convective Organization: Self-Organized Criticality or Homeostasis?

NASA Astrophysics Data System (ADS)

Yano, Jun-Ichi

2015-04-01

Atmospheric convection has a tendency organized on a hierarchy of scales ranging from the mesoscale to the planetary scales, with the latter especially manifested by the Madden-Julian oscillation. The present talk examines two major possible mechanisms of self-organization identified in wider literature from a phenomenological thermodynamic point of view by analysing a planetary-scale cloud-resolving model simulation. The first mechanism is self-organized criticality. A saturation tendency of precipitation rate with the increasing column-integrated water, reminiscence of critical phenomena, indicates self-organized criticality. The second is a self-regulation mechanism that is known as homeostasis in biology. A thermodynamic argument suggests that such self-regulation maintains the column-integrated water below a threshold by increasing the precipitation rate. Previous analyses of both observational data as well as cloud-resolving model (CRM) experiments give mixed results. A satellite data analysis suggests self-organized criticality. Some observational data as well as CRM experiments support homeostasis. Other analyses point to a combination of these two interpretations. In this study, a CRM experiment over a planetary-scale domain with a constant sea-surface temperature is analyzed. This analysis shows that the relation between the column-integrated total water and precipitation suggests self-organized criticality, whereas the one between the column-integrated water vapor and precipitation suggests homeostasis. The concurrent presence of these two mechanisms are further elaborated by detailed statistical and budget analyses. These statistics are scale invariant, reflecting a spatial scaling of precipitation processes. These self-organization mechanisms are most likely be best theoretically understood by the energy cycle of the convective systems consisting of the kinetic energy and the cloud-work function. The author has already investigated the behavior of this cycle system under a zero-dimensional configuration. Preliminary simulations of this cycle system over a two-dimensional domain will be presented.

Scaling prospects in mechanical energy harvesting with piezo nanowires

NASA Astrophysics Data System (ADS)

Ardila, Gustavo; Hinchet, Ronan; Mouis, Mireille; Montès, Laurent

2013-07-01

The combination of 3D processing technologies, low power circuits and new materials integration makes it conceivable to build autonomous integrated systems, which would harvest their energy from the environment. In this paper, we focus on mechanical energy harvesting and discuss its scaling prospects toward the use of piezoelectric nanostructures, able to be integrated in a CMOS environment. It is shown that direct scaling of present MEMS-based methodologies would be beneficial for high-frequency applications only. For the range of applications which is presently foreseen, a different approach is needed, based on energy harvesting from direct real-time deformation instead of energy harvesting from vibration modes at or close to resonance. We discuss the prospects of such an approach based on simple scaling rules Contribution to the Topical Issue “International Semiconductor Conference Dresden-Grenoble - ISCDG 2012”, Edited by Gérard Ghibaudo, Francis Balestra and Simon Deleonibus.

Computational singular perturbation analysis of stochastic chemical systems with stiffness

NASA Astrophysics Data System (ADS)

Wang, Lijin; Han, Xiaoying; Cao, Yanzhao; Najm, Habib N.

2017-04-01

Computational singular perturbation (CSP) is a useful method for analysis, reduction, and time integration of stiff ordinary differential equation systems. It has found dominant utility, in particular, in chemical reaction systems with a large range of time scales at continuum and deterministic level. On the other hand, CSP is not directly applicable to chemical reaction systems at micro or meso-scale, where stochasticity plays an non-negligible role and thus has to be taken into account. In this work we develop a novel stochastic computational singular perturbation (SCSP) analysis and time integration framework, and associated algorithm, that can be used to not only construct accurately and efficiently the numerical solutions to stiff stochastic chemical reaction systems, but also analyze the dynamics of the reduced stochastic reaction systems. The algorithm is illustrated by an application to a benchmark stochastic differential equation model, and numerical experiments are carried out to demonstrate the effectiveness of the construction.

Semantic Representation and Scale-Up of Integrated Air Traffic Management Data

NASA Technical Reports Server (NTRS)

Keller, Richard M.; Ranjan, Shubha; Wei, Mei Y.; Eshow, Michelle M.

2016-01-01

Each day, the global air transportation industry generates a vast amount of heterogeneous data from air carriers, air traffic control providers, and secondary aviation entities handling baggage, ticketing, catering, fuel delivery, and other services. Generally, these data are stored in isolated data systems, separated from each other by significant political, regulatory, economic, and technological divides. These realities aside, integrating aviation data into a single, queryable, big data store could enable insights leading to major efficiency, safety, and cost advantages. In this paper, we describe an implemented system for combining heterogeneous air traffic management data using semantic integration techniques. The system transforms data from its original disparate source formats into a unified semantic representation within an ontology-based triple store. Our initial prototype stores only a small sliver of air traffic data covering one day of operations at a major airport. The paper also describes our analysis of difficulties ahead as we prepare to scale up data storage to accommodate successively larger quantities of data -- eventually covering all US commercial domestic flights over an extended multi-year timeframe. We review several approaches to mitigating scale-up related query performance concerns.

Is vertical integration adding value to health systems?

PubMed

Weil, T P

2000-04-01

Vertical integration is a concept used by health systems when attempting to achieve economies of scale, greater coordination of services, and improved market penetration. This article focuses on the actual outcomes of utilizing vertical integration in the health field and then compares these findings with those reported in other industries. This analysis concludes that this organizational model does not work particularly well in the health industry, as illustrated by health alliances' poor fiscal performance when they acquire physician practices or when they start their own HMO plans.

Metallization failures

NASA Technical Reports Server (NTRS)

Beatty, R.

1971-01-01

Metallization-related failure mechanisms were shown to be a major cause of integrated circuit failures under accelerated stress conditions, as well as in actual use under field operation. The integrated circuit industry is aware of the problem and is attempting to solve it in one of two ways: (1) better understanding of the aluminum system, which is the most widely used metallization material for silicon integrated circuits both as a single level and multilevel metallization, or (2) evaluating alternative metal systems. Aluminum metallization offers many advantages, but also has limitations particularly at elevated temperatures and high current densities. As an alternative, multilayer systems of the general form, silicon device-metal-inorganic insulator-metal, are being considered to produce large scale integrated arrays. The merits and restrictions of metallization systems in current usage and systems under development are defined.

Energy Systems Integration Partnerships: NREL + Cogent Energy Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berdahl, Sonja E

2017-08-09

NREL is collaborating with Cogent Energy Systems (Cogent) to introduce small-scale waste-to-energy technology in microgrids.The focus of the project is to test and demonstrate the feasibility, reliability, and usefulness of integrating electricity generated using a simulated syngas composition matching the syngas stream to be produced by a HelioStorm-based WTE gasifier to power a microgrid as a means of addressing and complementing the intermittency of other sources of electricity.

Integrating scales of seagrass monitoring to meet conservation needs

USGS Publications Warehouse

Neckles, Hilary A.; Kopp, Blaine S.; Peterson, Bradley J.; Pooler, Penelope S.

2012-01-01

We evaluated a hierarchical framework for seagrass monitoring in two estuaries in the northeastern USA: Little Pleasant Bay, Massachusetts, and Great South Bay/Moriches Bay, New York. This approach includes three tiers of monitoring that are integrated across spatial scales and sampling intensities. We identified monitoring attributes for determining attainment of conservation objectives to protect seagrass ecosystems from estuarine nutrient enrichment. Existing mapping programs provided large-scale information on seagrass distribution and bed sizes (tier 1 monitoring). We supplemented this with bay-wide, quadrat-based assessments of seagrass percent cover and canopy height at permanent sampling stations following a spatially distributed random design (tier 2 monitoring). Resampling simulations showed that four observations per station were sufficient to minimize bias in estimating mean percent cover on a bay-wide scale, and sample sizes of 55 stations in a 624-ha system and 198 stations in a 9,220-ha system were sufficient to detect absolute temporal increases in seagrass abundance from 25% to 49% cover and from 4% to 12% cover, respectively. We made high-resolution measurements of seagrass condition (percent cover, canopy height, total and reproductive shoot density, biomass, and seagrass depth limit) at a representative index site in each system (tier 3 monitoring). Tier 3 data helped explain system-wide changes. Our results suggest tiered monitoring as an efficient and feasible way to detect and predict changes in seagrass systems relative to multi-scale conservation objectives.

Photonic content-addressable memory system that uses a parallel-readout optical disk

NASA Astrophysics Data System (ADS)

Krishnamoorthy, Ashok V.; Marchand, Philippe J.; Yayla, Gökçe; Esener, Sadik C.

1995-11-01

We describe a high-performance associative-memory system that can be implemented by means of an optical disk modified for parallel readout and a custom-designed silicon integrated circuit with parallel optical input. The system can achieve associative recall on 128 \\times 128 bit images and also on variable-size subimages. The system's behavior and performance are evaluated on the basis of experimental results on a motionless-head parallel-readout optical-disk system, logic simulations of the very-large-scale integrated chip, and a software emulation of the overall system.

Bioprocess scale-up/down as integrative enabling technology: from fluid mechanics to systems biology and beyond.

PubMed

Delvigne, Frank; Takors, Ralf; Mudde, Rob; van Gulik, Walter; Noorman, Henk

2017-09-01

Efficient optimization of microbial processes is a critical issue for achieving a number of sustainable development goals, considering the impact of microbial biotechnology in agrofood, environment, biopharmaceutical and chemical industries. Many of these applications require scale-up after proof of concept. However, the behaviour of microbial systems remains unpredictable (at least partially) when shifting from laboratory-scale to industrial conditions. The need for robust microbial systems is thus highly needed in this context, as well as a better understanding of the interactions between fluid mechanics and cell physiology. For that purpose, a full scale-up/down computational framework is already available. This framework links computational fluid dynamics (CFD), metabolic flux analysis and agent-based modelling (ABM) for a better understanding of the cell lifelines in a heterogeneous environment. Ultimately, this framework can be used for the design of scale-down simulators and/or metabolically engineered cells able to cope with environmental fluctuations typically found in large-scale bioreactors. However, this framework still needs some refinements, such as a better integration of gas-liquid flows in CFD, and taking into account intrinsic biological noise in ABM. © 2017 The Authors. Microbial Biotechnology published by John Wiley & Sons Ltd and Society for Applied Microbiology.

Block Preconditioning to Enable Physics-Compatible Implicit Multifluid Plasma Simulations

NASA Astrophysics Data System (ADS)

Phillips, Edward; Shadid, John; Cyr, Eric; Miller, Sean

2017-10-01

Multifluid plasma simulations involve large systems of partial differential equations in which many time-scales ranging over many orders of magnitude arise. Since the fastest of these time-scales may set a restrictively small time-step limit for explicit methods, the use of implicit or implicit-explicit time integrators can be more tractable for obtaining dynamics at time-scales of interest. Furthermore, to enforce properties such as charge conservation and divergence-free magnetic field, mixed discretizations using volume, nodal, edge-based, and face-based degrees of freedom are often employed in some form. Together with the presence of stiff modes due to integrating over fast time-scales, the mixed discretization makes the required linear solves for implicit methods particularly difficult for black box and monolithic solvers. This work presents a block preconditioning strategy for multifluid plasma systems that segregates the linear system based on discretization type and approximates off-diagonal coupling in block diagonal Schur complement operators. By employing multilevel methods for the block diagonal subsolves, this strategy yields algorithmic and parallel scalability which we demonstrate on a range of problems.

Photonic Integrated Circuits

NASA Technical Reports Server (NTRS)

Krainak, Michael; Merritt, Scott

2016-01-01

Integrated photonics generally is the integration of multiple lithographically defined photonic and electronic components and devices (e.g. lasers, detectors, waveguides passive structures, modulators, electronic control and optical interconnects) on a single platform with nanometer-scale feature sizes. The development of photonic integrated circuits permits size, weight, power and cost reductions for spacecraft microprocessors, optical communication, processor buses, advanced data processing, and integrated optic science instrument optical systems, subsystems and components. This is particularly critical for small spacecraft platforms. We will give an overview of some NASA applications for integrated photonics.

Pioneering University/Industry Venture Explores VLSI Frontiers.

ERIC Educational Resources Information Center

Davis, Dwight B.

1983-01-01

Discusses industry-sponsored programs in semiconductor research, focusing on Stanford University's Center for Integrated Systems (CIS). CIS, while pursuing research in semiconductor very-large-scale integration, is merging the fields of computer science, information science, and physical science. Issues related to these university/industry…

Potentials of an integrated biomass utilization system: Estimation of carbon flow and energy consumption

NASA Astrophysics Data System (ADS)

Suzuki, Ryosuke; Nishimura, Motoki; Yuan, Lee Chang; Kamahara, Hirotsugu; Atsuta, Yoichi; Daimon, Hiroyuki

2017-10-01

Utilization of sewage sludge using anaerobic digestion has been promoted for decades. However, it is still relatively uncommon especially in Japan. As an approach to promote the utilization of sewage sludge using anaerobic digestion, an integrated system that combines anaerobic digestion with greenhouse, composting and seaweed cultivation was proposed. Based on the concept of the integrated system, not only sewage sludge can be treated using anaerobic digestion that creates green energy, but also the by-products such as CO2 and heat produced during the process can be utilized for crops production. In this study, the potentials of such integrated system were discussed through the estimation of possible commercialized scale as well as comparison of energy consumption with conventional approach for sewage sludge treatment, which is the incineration. The estimation of possible commercialized scale was calculated based on the carbon flow of the system. Results showed that 25% of the current total electricity of the wastewater treatment plant can be covered by the energy produced using anaerobic digestion of sewage sludge. It was estimated that the total energy consumption of the integrated system was actually 14% lower when compared to incineration approach. In addition to the large amount of crops that can be produced, all in all this study aimed to be the showcase of the potentials of sewage sludge as a biomass by implementing the proposed integrated system. The extra values of producing crops through the utilization of CO2 and heat can serve as a stimulus to the public, which would surely lead to higher interest to implement the utilization of sewage sludge using anaerobic digestion.

Co-governing decentralised water systems: an analytical framework.

PubMed

Yu, C; Brown, R; Morison, P

2012-01-01

Current discourses in urban water management emphasise a diversity of water sources and scales of infrastructure for resilience and adaptability. During the last 2 decades, in particular, various small-scale systems emerged and developed so that the debate has largely moved from centralised versus decentralised water systems toward governing integrated and networked systems of provision and consumption where small-scale technologies are embedded in large-scale centralised infrastructures. However, while centralised systems have established boundaries of ownership and management, decentralised water systems (such as stormwater harvesting technologies for the street, allotment/house scales) do not, therefore the viability for adoption and/or continued use of decentralised water systems is challenged. This paper brings together insights from the literature on public sector governance, co-production and social practices model to develop an analytical framework for co-governing such systems. The framework provides urban water practitioners with guidance when designing co-governance arrangements for decentralised water systems so that these systems continue to exist, and become widely adopted, within the established urban water regime.

Sustainability. Systems integration for global sustainability.

PubMed

Liu, Jianguo; Mooney, Harold; Hull, Vanessa; Davis, Steven J; Gaskell, Joanne; Hertel, Thomas; Lubchenco, Jane; Seto, Karen C; Gleick, Peter; Kremen, Claire; Li, Shuxin

2015-02-27

Global sustainability challenges, from maintaining biodiversity to providing clean air and water, are closely interconnected yet often separately studied and managed. Systems integration—holistic approaches to integrating various components of coupled human and natural systems—is critical to understand socioeconomic and environmental interconnections and to create sustainability solutions. Recent advances include the development and quantification of integrated frameworks that incorporate ecosystem services, environmental footprints, planetary boundaries, human-nature nexuses, and telecoupling. Although systems integration has led to fundamental discoveries and practical applications, further efforts are needed to incorporate more human and natural components simultaneously, quantify spillover systems and feedbacks, integrate multiple spatial and temporal scales, develop new tools, and translate findings into policy and practice. Such efforts can help address important knowledge gaps, link seemingly unconnected challenges, and inform policy and management decisions. Copyright © 2015, American Association for the Advancement of Science.

Systems safety monitoring using the National Full-Scale Aerodynamic Complex Bar Chart Monitor

NASA Technical Reports Server (NTRS)

Jung, Oscar

1990-01-01

Attention is given to the Bar Chart Monitor system designed for safety monitoring of all model and facility test-related articles in wind tunnels. The system's salient features and its integration into the data acquisition system are discussed.

FRIDA: diffraction-limited imaging and integral-field spectroscopy for the GTC

NASA Astrophysics Data System (ADS)

Watson, Alan M.; Acosta-Pulido, José A.; Álvarez-Núñez, Luis C.; Bringas-Rico, Vicente; Cardiel, Nicolás.; Cardona, Salvador; Chapa, Oscar; Díaz García, José Javier; Eikenberry, Stephen S.; Espejo, Carlos; Flores-Meza, Rubén. A.; Fuentes-Fernández, Jorge; Gallego, Jesús; Garcés Medina, José Leonardo; Garzón López, Francisco; Hammersley, Peter; Keiman, Carolina; Lara, Gerardo; López, José Alberto; López, Pablo L.; Lucero, Diana; Moreno Arce, Heidy; Pascual Ramirez, Sergio; Patrón Recio, Jesús; Prieto, Almudena; Rodríguez, Alberto José; Marco de la Rosa, José; Sánchez, Beatriz; Uribe, Jorge A.; Váldez Berriozabal, Francisco

2016-08-01

FRIDA is a diffraction-limited imager and integral-field spectrometer that is being built for the adaptive-optics focus of the Gran Telescopio Canarias. In imaging mode FRIDA will provide scales of 0.010, 0.020 and 0.040 arcsec/pixel and in IFS mode spectral resolutions of 1500, 4000 and 30,000. FRIDA is starting systems integration and is scheduled to complete fully integrated system tests at the laboratory by the end of 2017 and to be delivered to GTC shortly thereafter. In this contribution we present a summary of its design, fabrication, current status and potential scientific applications.

An integrated probe design for measuring food quality in a microwave environment

NASA Astrophysics Data System (ADS)

O'Farrell, M.; Sheridan, C.; Lewis, E.; Zhao, W. Z.; Sun, T.; Grattan, K. T. V.

2007-07-01

The work presented describes the development of a novel integrated optical sensor system for the simultaneous and online measurement of the colour and temperature of food as it cooks in a large-scale microwave and hybrid oven systems. The integrated probe contains two different sensor concepts, one to monitor temperature and based on Fibre Bragg Grating (FBG) technology and a second for meat quality, based on reflection spectroscopy in the visible wavelength range. The combination of the two sensors into a single probe requires a careful configuration of the sensor approaches in the creation of an integrated probe design.

Full-Scaled Advanced Systems Testbed: Ensuring Success of Adaptive Control Research Through Project Lifecycle Risk Mitigation

NASA Technical Reports Server (NTRS)

Pavlock, Kate M.

2011-01-01

The National Aeronautics and Space Administration's Dryden Flight Research Center completed flight testing of adaptive controls research on the Full-Scale Advance Systems Testbed (FAST) in January of 2011. The research addressed technical challenges involved with reducing risk in an increasingly complex and dynamic national airspace. Specific challenges lie with the development of validated, multidisciplinary, integrated aircraft control design tools and techniques to enable safe flight in the presence of adverse conditions such as structural damage, control surface failures, or aerodynamic upsets. The testbed is an F-18 aircraft serving as a full-scale vehicle to test and validate adaptive flight control research and lends a significant confidence to the development, maturation, and acceptance process of incorporating adaptive control laws into follow-on research and the operational environment. The experimental systems integrated into FAST were designed to allow for flexible yet safe flight test evaluation and validation of modern adaptive control technologies and revolve around two major hardware upgrades: the modification of Production Support Flight Control Computers (PSFCC) and integration of two, fourth-generation Airborne Research Test Systems (ARTS). Post-hardware integration verification and validation provided the foundation for safe flight test of Nonlinear Dynamic Inversion and Model Reference Aircraft Control adaptive control law experiments. To ensure success of flight in terms of cost, schedule, and test results, emphasis on risk management was incorporated into early stages of design and flight test planning and continued through the execution of each flight test mission. Specific consideration was made to incorporate safety features within the hardware and software to alleviate user demands as well as into test processes and training to reduce human factor impacts to safe and successful flight test. This paper describes the research configuration, experiment functionality, overall risk mitigation, flight test approach and results, and lessons learned of adaptive controls research of the Full-Scale Advanced Systems Testbed.

On generic obstructions to recovering correct statistics from climate simulations: Homogenization for deterministic maps and multiplicative noise

NASA Astrophysics Data System (ADS)

Gottwald, Georg; Melbourne, Ian

2013-04-01

Whereas diffusion limits of stochastic multi-scale systems have a long and successful history, the case of constructing stochastic parametrizations of chaotic deterministic systems has been much less studied. We present rigorous results of convergence of a chaotic slow-fast system to a stochastic differential equation with multiplicative noise. Furthermore we present rigorous results for chaotic slow-fast maps, occurring as numerical discretizations of continuous time systems. This raises the issue of how to interpret certain stochastic integrals; surprisingly the resulting integrals of the stochastic limit system are generically neither of Stratonovich nor of Ito type in the case of maps. It is shown that the limit system of a numerical discretisation is different to the associated continuous time system. This has important consequences when interpreting the statistics of long time simulations of multi-scale systems - they may be very different to the one of the original continuous time system which we set out to study.

Sustainable NREL: From Integration to Innovation

DOE Office of Scientific and Technical Information (OSTI.GOV)

2015-09-01

NREL's sustainability practices are integrated throughout the laboratory and are essential to our mission to develop clean energy and energy efficiency technologies and practices, advance related science and engineering, and provide knowledge and innovations to integrate energy systems at all scales. Sustainability initiatives are integrated through our campus, our staff, and our environment allowing NREL to provide leadership in modeling a sustainability energy future for companies, organizations, governments, and communities.

Evaluation of Kirkwood-Buff integrals via finite size scaling: a large scale molecular dynamics study

NASA Astrophysics Data System (ADS)

Dednam, W.; Botha, A. E.

2015-01-01

Solvation of bio-molecules in water is severely affected by the presence of co-solvent within the hydration shell of the solute structure. Furthermore, since solute molecules can range from small molecules, such as methane, to very large protein structures, it is imperative to understand the detailed structure-function relationship on the microscopic level. For example, it is useful know the conformational transitions that occur in protein structures. Although such an understanding can be obtained through large-scale molecular dynamic simulations, it is often the case that such simulations would require excessively large simulation times. In this context, Kirkwood-Buff theory, which connects the microscopic pair-wise molecular distributions to global thermodynamic properties, together with the recently developed technique, called finite size scaling, may provide a better method to reduce system sizes, and hence also the computational times. In this paper, we present molecular dynamics trial simulations of biologically relevant low-concentration solvents, solvated by aqueous co-solvent solutions. In particular we compare two different methods of calculating the relevant Kirkwood-Buff integrals. The first (traditional) method computes running integrals over the radial distribution functions, which must be obtained from large system-size NVT or NpT simulations. The second, newer method, employs finite size scaling to obtain the Kirkwood-Buff integrals directly by counting the particle number fluctuations in small, open sub-volumes embedded within a larger reservoir that can be well approximated by a much smaller simulation cell. In agreement with previous studies, which made a similar comparison for aqueous co-solvent solutions, without the additional solvent, we conclude that the finite size scaling method is also applicable to the present case, since it can produce computationally more efficient results which are equivalent to the more costly radial distribution function method.

Integrating Phenological, Trait and Environmental Data For Continental Scale Analysis: A Community Approach

NASA Astrophysics Data System (ADS)

Weltzin, J. F.; Walls, R.; Guralnick, R. P.; Rosemartin, A.; Deck, J.; Powers, L. A.

2014-12-01

There is a wealth of biodiversity and environmental data that can provide the basis for addressing global scale questions of societal concern. However, our ability to discover, access and integrate these data for use in broader analyses is hampered by the lack of standardized languages and systems. New tools (e.g. ontologies, data standards, integration tools, unique identifiers) are being developed that enable establishment of a framework for linked and open data. Relative to other domains, these tools are nascent in biodiversity and environmental sciences and will require effort to develop, though work can capitalize on lessons learned from previous efforts. Here we discuss needed next steps to provide consistently described and formatted ecological data for immediate application in ecological analysis, focusing on integrating phenology, trait and environmental data to understand local to continental-scale biophysical processes and inform natural resource management practices. As more sources of data become available at finer spatial and temporal resolution, e.g., from national standardized earth observing systems (e.g., NEON, LTER and LTAR Networks, USA NPN), these challenges will become more acute. Here we provide an overview of the standards and ontology development landscape specifically related to phenological and trait data, and identify requirements to overcome current challenges. Second, we outline a workflow for formatting and integrating existing datasets to address key scientific and resource management questions such as: "What traits determine differential phenological responses to changing environmental conditions?" or "What is the role of granularity of observation, and of spatiotemporal scale, in controlling phenological responses to different driving variables?" Third, we discuss methods to semantically annotate datasets to greatly decrease time needed to assemble heterogeneous data for use in ecological analyses on varying spatial scales. We close by making a call to interested community members for a working group to model phenology, trait and environmental data products from continental-scale efforts (e.g. NEON, USA-NPN and others) focusing on ways to assure discoverability and interoperability.

A Systems Approach to Exposure Modeling (ExpoCast)(FutureTox3)

EPA Science Inventory

Systems Biology might be described as the understanding of how interactions on multiple scales integrate into a homeostatic system. Systems Toxicology could then be the study of the impact of chemical perturbations of homeostasis. Systems exposure might then be the study of the i...

Development of a School Bus Fuel System Integrity Compliance Procedure. Final Report.

ERIC Educational Resources Information Center

Morrow, G. W.; Johnson, N. B.

This report presents a program that derived a compliance test procedure for school buses with a gross vehicle weight of 10,000 pounds or greater. The objective of this program was to evaluate Fuel System Integrity (FMVSS 301) in relation to school buses, conduct a limited state-of-the-art survey and run full-scale dynamic tests to produce an…

Slow dynamics in translation-invariant quantum lattice models

NASA Astrophysics Data System (ADS)

Michailidis, Alexios A.; Žnidarič, Marko; Medvedyeva, Mariya; Abanin, Dmitry A.; Prosen, Tomaž; Papić, Z.

2018-03-01

Many-body quantum systems typically display fast dynamics and ballistic spreading of information. Here we address the open problem of how slow the dynamics can be after a generic breaking of integrability by local interactions. We develop a method based on degenerate perturbation theory that reveals slow dynamical regimes and delocalization processes in general translation invariant models, along with accurate estimates of their delocalization time scales. Our results shed light on the fundamental questions of the robustness of quantum integrable systems and the possibility of many-body localization without disorder. As an example, we construct a large class of one-dimensional lattice models where, despite the absence of asymptotic localization, the transient dynamics is exceptionally slow, i.e., the dynamics is indistinguishable from that of many-body localized systems for the system sizes and time scales accessible in experiments and numerical simulations.

Diagnosing scaling behavior of groundwater with a fully-integrated, high resolution hydrologic model simulated over the continental US (Invited)

NASA Astrophysics Data System (ADS)

Maxwell, R. M.; Condon, L. E.; Kollet, S. J.

2013-12-01

Groundwater is an important component of the hydrologic cycle yet its importance is often overlooked. Aquifers are a critical water resource, particularly in irrigation, but also participates in moderating the land-energy balance over the so-called critical zone of 2-10m in water table depth. Yet,the scaling behavior of groundwater is not well known. Here, we present the results of a fully-integrated hydrologic model run over a 6.3M km2 domain that covers much of North America focused on the continental United States. This model encompasses both the Mississippi and Colorado River watersheds in their entirety at 1km resolution and is constructed using the fully-integrated groundwater-vadose zone-surface water-land surface model, ParFlow. Results from this work are compared to observations (both of surface water flow and groundwater depths) and approaches are presented for observing of these integrated systems. Furthermore, results are used to understand the scaling behavior of groundwater over the continent at high resolution. Implications for understanding dominant hydrological processes at large scales will be discussed.

Built-In Data-Flow Integration Testing in Large-Scale Component-Based Systems

NASA Astrophysics Data System (ADS)

Piel, Éric; Gonzalez-Sanchez, Alberto; Gross, Hans-Gerhard

Modern large-scale component-based applications and service ecosystems are built following a number of different component models and architectural styles, such as the data-flow architectural style. In this style, each building block receives data from a previous one in the flow and sends output data to other components. This organisation expresses information flows adequately, and also favours decoupling between the components, leading to easier maintenance and quicker evolution of the system. Integration testing is a major means to ensure the quality of large systems. Their size and complexity, together with the fact that they are developed and maintained by several stake holders, make Built-In Testing (BIT) an attractive approach to manage their integration testing. However, so far no technique has been proposed that combines BIT and data-flow integration testing. We have introduced the notion of a virtual component in order to realize such a combination. It permits to define the behaviour of several components assembled to process a flow of data, using BIT. Test-cases are defined in a way that they are simple to write and flexible to adapt. We present two implementations of our proposed virtual component integration testing technique, and we extend our previous proposal to detect and handle errors in the definition by the user. The evaluation of the virtual component testing approach suggests that more issues can be detected in systems with data-flows than through other integration testing approaches.

Projecting state-level air pollutant emissions using an integrated assessment model: GCAM-USA.

EPA Science Inventory

Integrated Assessment Models (IAMs) characterize the interactions among human and earth systems. IAMs typically have been applied to investigate future energy, land use, and emission pathways at global to continental scales. Recent directions in IAM development include enhanced t...

Moisture effect on interfacial integrity of epoxy-bonded system: a hierarchical approach

NASA Astrophysics Data System (ADS)

Tam, Lik-ho; Lun Chow, Cheuk; Lau, Denvid

2018-01-01

The epoxy-bonded system has been widely used in various applications across different scale lengths. Prior investigations have indicated that the moisture-affected interfacial debonding is the major failure mode of such a system, but the fundamental mechanism remains unknown, such as the basis for the invasion of water molecules in the cross-linked epoxy and the epoxy-bonded interface. This prevents us from predicting the long-term performance of the epoxy-related applications under the effect of the moisture. Here, we use full atomistic models to investigate the response of the epoxy-bonded system towards the adhesion test, and provide a detailed analysis of the interfacial integrity under the moisture effect and the associated debonding mechanism. Molecular dynamics simulations show that water molecules affect the hierarchical structure of the epoxy-bonded system at the nanoscale by disrupting the film-substrate interaction and the molecular interaction within the epoxy, which leads to the detachment of the epoxy thin film, and the final interfacial debonding. The simulation results show good agreement with the experimental results of the epoxy-bonded system. Through identifying the relationship between the epoxy structure and the debonding mechanism at multiple scales, it is shown that the hierarchical structure of the epoxy-bonded system is crucial for the interfacial integrity. In particular, the available space of the epoxy-bonded system, which consists of various sizes ranging from the atomistic scale to the macroscale and is close to the interface facilitates the moisture accumulation, leading to a distinct interfacial debonding when compared to the dry scenario.

A monolithically integrated polarization entangled photon pair source on a silicon chip

PubMed Central

Matsuda, Nobuyuki; Le Jeannic, Hanna; Fukuda, Hiroshi; Tsuchizawa, Tai; Munro, William John; Shimizu, Kaoru; Yamada, Koji; Tokura, Yasuhiro; Takesue, Hiroki

2012-01-01

Integrated photonic circuits are one of the most promising platforms for large-scale photonic quantum information systems due to their small physical size and stable interferometers with near-perfect lateral-mode overlaps. Since many quantum information protocols are based on qubits defined by the polarization of photons, we must develop integrated building blocks to generate, manipulate, and measure the polarization-encoded quantum state on a chip. The generation unit is particularly important. Here we show the first integrated polarization-entangled photon pair source on a chip. We have implemented the source as a simple and stable silicon-on-insulator photonic circuit that generates an entangled state with 91 ± 2% fidelity. The source is equipped with versatile interfaces for silica-on-silicon or other types of waveguide platforms that accommodate the polarization manipulation and projection devices as well as pump light sources. Therefore, we are ready for the full-scale implementation of photonic quantum information systems on a chip. PMID:23150781

Guide for Regional Integrated Assessments: Handbook of Methods and Procedures, Version 5.1. Appendix 1

NASA Technical Reports Server (NTRS)

Rosenzweig, Cynthia E.; Jones, James W.; Hatfield, Jerry; Antle, John; Ruane, Alex; Boote, Ken; Thorburn, Peter; Valdivia, Roberto; Porter, Cheryl; Janssen, Sander;

A Systematic Multi-Time Scale Solution for Regional Power Grid Operation

NASA Astrophysics Data System (ADS)

Zhu, W. J.; Liu, Z. G.; Cheng, T.; Hu, B. Q.; Liu, X. Z.; Zhou, Y. F.

2017-10-01

Many aspects need to be taken into consideration in a regional grid while making schedule plans. In this paper, a systematic multi-time scale solution for regional power grid operation considering large scale renewable energy integration and Ultra High Voltage (UHV) power transmission is proposed. In the time scale aspect, we discuss the problem from month, week, day-ahead, within-day to day-behind, and the system also contains multiple generator types including thermal units, hydro-plants, wind turbines and pumped storage stations. The 9 subsystems of the scheduling system are described, and their functions and relationships are elaborated. The proposed system has been constructed in a provincial power grid in Central China, and the operation results further verified the effectiveness of the system.

Unlocking Flexibility: Energy Systems Integration [Guest Editorial

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Malley, Mark; Kroposki, Benjamin

2017-01-01

The articles in this special section focus on energy systems integration (ESI). Electric power systems around the world are experiencing great changes, including the retirement of coal and nuclear plants along with a rapid increase in the use of natural gas turbines and variable renewable technologies such as wind and solar. There is also much more use of information and communications technologies to enhance the visibility and controllability of the grid. Flexibility of operation, the ability of a power system to respond to change in demand and supply, is critical to enable higher levels of variable generation. One way tomore » unlock this potential flexibility is to tap into other energy domains. This concept of interconnecting energy domains is called ESI. ESI is the process of coordinating the operation and planning of energy systems across multiple pathways and/or geographical scales to deliver reliable, cost-effective energy services with minimal impact on the environment. Integrating energy domains adds flexibility to the electrical power system. ESI includes interactions among energy vectors and with other large-scale infrastructures including water, transport, and data and communications networks, which are an enabling technology for ESI.« less

Output Control Technologies for a Large-scale PV System Considering Impacts on a Power Grid

NASA Astrophysics Data System (ADS)

Kuwayama, Akira

The mega-solar demonstration project named “Verification of Grid Stabilization with Large-scale PV Power Generation systems” had been completed in March 2011 at Wakkanai, the northernmost city of Japan. The major objectives of this project were to evaluate adverse impacts of large-scale PV power generation systems connected to the power grid and develop output control technologies with integrated battery storage system. This paper describes the outline and results of this project. These results show the effectiveness of battery storage system and also proposed output control methods for a large-scale PV system to ensure stable operation of power grids. NEDO, New Energy and Industrial Technology Development Organization of Japan conducted this project and HEPCO, Hokkaido Electric Power Co., Inc managed the overall project.

CCSI and the role of advanced computing in accelerating the commercial deployment of carbon capture systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, David; Agarwal, Deborah A.; Sun, Xin

2011-09-01

The Carbon Capture Simulation Initiative is developing state-of-the-art computational modeling and simulation tools to accelerate the commercialization of carbon capture technology. The CCSI Toolset consists of an integrated multi-scale modeling and simulation framework, which includes extensive use of reduced order models (ROMs) and a comprehensive uncertainty quantification (UQ) methodology. This paper focuses on the interrelation among high performance computing, detailed device simulations, ROMs for scale-bridging, UQ and the integration framework.

CCSI and the role of advanced computing in accelerating the commercial deployment of carbon capture systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, D.; Agarwal, D.; Sun, X.

2011-01-01

The Carbon Capture Simulation Initiative is developing state-of-the-art computational modeling and simulation tools to accelerate the commercialization of carbon capture technology. The CCSI Toolset consists of an integrated multi-scale modeling and simulation framework, which includes extensive use of reduced order models (ROMs) and a comprehensive uncertainty quantification (UQ) methodology. This paper focuses on the interrelation among high performance computing, detailed device simulations, ROMs for scale-bridging, UQ and the integration framework.

A fully reconfigurable photonic integrated signal processor

NASA Astrophysics Data System (ADS)

Liu, Weilin; Li, Ming; Guzzon, Robert S.; Norberg, Erik J.; Parker, John S.; Lu, Mingzhi; Coldren, Larry A.; Yao, Jianping

2016-03-01

Photonic signal processing has been considered a solution to overcome the inherent electronic speed limitations. Over the past few years, an impressive range of photonic integrated signal processors have been proposed, but they usually offer limited reconfigurability, a feature highly needed for the implementation of large-scale general-purpose photonic signal processors. Here, we report and experimentally demonstrate a fully reconfigurable photonic integrated signal processor based on an InP-InGaAsP material system. The proposed photonic signal processor is capable of performing reconfigurable signal processing functions including temporal integration, temporal differentiation and Hilbert transformation. The reconfigurability is achieved by controlling the injection currents to the active components of the signal processor. Our demonstration suggests great potential for chip-scale fully programmable all-optical signal processing.

A 14 × 14 μm2 footprint polarization-encoded quantum controlled-NOT gate based on hybrid waveguide

PubMed Central

Wang, S. M.; Cheng, Q. Q.; Gong, Y. X.; Xu, P.; Sun, C.; Li, L.; Li, T.; Zhu, S. N.

2016-01-01

Photonic quantum information processing system has been widely used in communication, metrology and lithography. The recent emphasis on the miniaturized photonic platform is thus motivated by the urgent need for realizing large-scale information processing and computing. Although the integrated quantum logic gates and quantum algorithms based on path encoding have been successfully demonstrated, the technology for handling another commonly used polarization-encoded qubits has yet to be fully developed. Here, we show the implementation of a polarization-dependent beam-splitter in the hybrid waveguide system. With precisely design, the polarization-encoded controlled-NOT gate can be implemented using only single such polarization-dependent beam-splitter with the significant size reduction of the overall device footprint to 14 × 14 μm2. The experimental demonstration of the highly integrated controlled-NOT gate sets the stage to develop large-scale quantum information processing system. Our hybrid design also establishes the new capabilities in controlling the polarization modes in integrated photonic circuits. PMID:27142992

A 14 × 14 μm(2) footprint polarization-encoded quantum controlled-NOT gate based on hybrid waveguide.

PubMed

Wang, S M; Cheng, Q Q; Gong, Y X; Xu, P; Sun, C; Li, L; Li, T; Zhu, S N

2016-05-04

Photonic quantum information processing system has been widely used in communication, metrology and lithography. The recent emphasis on the miniaturized photonic platform is thus motivated by the urgent need for realizing large-scale information processing and computing. Although the integrated quantum logic gates and quantum algorithms based on path encoding have been successfully demonstrated, the technology for handling another commonly used polarization-encoded qubits has yet to be fully developed. Here, we show the implementation of a polarization-dependent beam-splitter in the hybrid waveguide system. With precisely design, the polarization-encoded controlled-NOT gate can be implemented using only single such polarization-dependent beam-splitter with the significant size reduction of the overall device footprint to 14 × 14 μm(2). The experimental demonstration of the highly integrated controlled-NOT gate sets the stage to develop large-scale quantum information processing system. Our hybrid design also establishes the new capabilities in controlling the polarization modes in integrated photonic circuits.

Integrated propulsion/energy transfer control systems for lift-fan V/STOL aircraft. [reduction of total propulsion system and control system installation requirements

NASA Technical Reports Server (NTRS)

Deckert, W. H.; Rolls, L. S.

1974-01-01

An integrated propulsion/control system for lift-fan transport aircraft is described. System behavior from full-scale experimental and piloted simulator investigations are reported. The lift-fan transport is a promising concept for short-to-medium haul civil transportation and for other missions. The lift-fan transport concept features high cruise airspeed, favorable ride qualities, small perceived noise footprints, high utilization, transportation system flexibility, and adaptability to VTOL, V/STOL, or STOL configurations. The lift-fan transport has high direct operating costs in comparison to conventional aircraft, primarily because of propulsion system and aircraft low-speed control system installation requirements. An integrated lift-fan propulsion system/aircraft low-speed control system that reduces total propulsion system and control system installation requirements is discussed.

Results of a jet plume effects test on Rockwell International integrated space shuttle vehicle using a vehicle 5 configuration 0.02-scale model (88-OTS) in the 11 by 11 foot leg of the NASA/Ames Research Center unitary plan wind tunnel (IA19), volume 1

NASA Technical Reports Server (NTRS)

Nichols, M. E.

1975-01-01

Results are presented of jet plume effects test IA19 using a vehicle 5 configuration integrated space shuttle vehicle 0.02-scale model in the NASA/Ames Research Center 11 x 11-foot leg of the unitary plan wind tunnel. The jet plume power effects on the integrated vehicle static pressure distribution were determined along with elevon, main propulsion system nozzle, and solid rocket booster nozzle effectiveness and elevon hinge moments.

Oxygen Transfer in Moving Bed Biofilm Reactor and Integrated Fixed Film Activated Sludge Processes.

PubMed

2017-11-17

A demonstrated approach to design the, so-called, medium-bubble air diffusion network for oxygen transfer into the aerobic zone(s) of moving bed biofilm reactor (MBBR) and integrated fixed-film activated sludge (IFAS) processes is described in this paper. Operational full-scale biological water resource recovery systems treating municipal sewerage demonstrate that medium-bubble air diffusion networks designed using the method presented here provide reliable service. Further improvement is possible, however, as knowledge gaps prevent more rational process designs. Filling such knowledge gaps can potentially result in higher performing and more economical systems. Small-scale system testing demonstrates significant enhancement of oxygen transfer capacity due to the presence of media, but quantification of such effects in full-scale systems is lacking, and is needed. Establishment of the relationship between diffuser submergence, aeration rate, and biofilm carrier fill fraction will enhance MBBR and IFAS aerobic process design, cost, and performance. Limited testing of full-scale systems is available to allow computation of alpha valuess. As with clean water testing of full-scale systems, further full-scale testing under actual operating conditions is required to more fully quantify MBBR and IFAS system oxygen transfer performance under a wide range of operating conditions. Control of MBBR and IFAS aerobic zone oxygen transfer systems can be optimized by recognizing that varying residual dissolved oxygen (DO) concentrations are needed, depending on operating conditions. For example, the DO concentration in the aerobic zone of nitrifying IFAS processes can be lowered during warm weather conditions when greater suspended growth nitrification can occur, resulting in the need for reduced nitrification by the biofilm compartment. Further application of oxygen transfer control approaches used in activated sludge systems to MBBR and IFAS systems, such as ammonia-based oxygen transfer system control, has been demonstrated to further improve MBBR and IFAS system energy-efficiency.

Report on all ARRA Funded Technical Work

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2013-10-05

The main focus of this American Recovery and Reinvestment Act of 2009 (ARRA) funded project was to design an energy efficient carbon capture and storage (CCS) process using the Recipients membrane system for H{sub 2} separation and CO{sub 2} capture. In the ARRA-funded project, the Recipient accelerated development and scale-up of ongoing hydrogen membrane technology research and development (R&D). Specifically, this project focused on accelerating the current R&D work scope of the base program-funded project, involving lab scale tests, detail design of a 250 lb/day H{sub 2} process development unit (PDU), and scale-up of membrane tube and coating manufacturing. Thismore » project scope included the site selection and a Front End Engineering Design (FEED) study of a nominally 4 to 10 ton-per-day (TPD) Pre-Commercial Module (PCM) hydrogen separation membrane system. Process models and techno-economic analysis were updated to include studies on integration of this technology into an Integrated Gasification Combined Cycle (IGCC) power generation system with CCS.« less

Extracting DNA from FFPE Tissue Biospecimens Using User-Friendly Automated Technology: Is There an Impact on Yield or Quality?

PubMed

Mathieson, William; Guljar, Nafia; Sanchez, Ignacio; Sroya, Manveer; Thomas, Gerry A

2018-05-03

DNA extracted from formalin-fixed, paraffin-embedded (FFPE) tissue blocks is amenable to analytical techniques, including sequencing. DNA extraction protocols are typically long and complex, often involving an overnight proteinase K digest. Automated platforms that shorten and simplify the process are therefore an attractive proposition for users wanting a faster turn-around or to process large numbers of biospecimens. It is, however, unclear whether automated extraction systems return poorer DNA yields or quality than manual extractions performed by experienced technicians. We extracted DNA from 42 FFPE clinical tissue biospecimens using the QiaCube (Qiagen) and ExScale (ExScale Biospecimen Solutions) automated platforms, comparing DNA yields and integrities with those from manual extractions. The QIAamp DNA FFPE Spin Column Kit was used for manual and QiaCube DNA extractions and the ExScale extractions were performed using two of the manufacturer's magnetic bead kits: one extracting DNA only and the other simultaneously extracting DNA and RNA. In all automated extraction methods, DNA yields and integrities (assayed using DNA Integrity Numbers from a 4200 TapeStation and the qPCR-based Illumina FFPE QC Assay) were poorer than in the manual method, with the QiaCube system performing better than the ExScale system. However, ExScale was fastest, offered the highest reproducibility when extracting DNA only, and required the least intervention or technician experience. Thus, the extraction methods have different strengths and weaknesses, would appeal to different users with different requirements, and therefore, we cannot recommend one method over another.

LS-DYNA Analysis of a Full-Scale Helicopter Crash Test

NASA Technical Reports Server (NTRS)

Annett, Martin S.

2010-01-01

A full-scale crash test of an MD-500 helicopter was conducted in December 2009 at NASA Langley's Landing and Impact Research facility (LandIR). The MD-500 helicopter was fitted with a composite honeycomb Deployable Energy Absorber (DEA) and tested under vertical and horizontal impact velocities of 26 ft/sec and 40 ft/sec, respectively. The objectives of the test were to evaluate the performance of the DEA concept under realistic crash conditions and to generate test data for validation of a system integrated LS-DYNA finite element model. In preparation for the full-scale crash test, a series of sub-scale and MD-500 mass simulator tests was conducted to evaluate the impact performances of various components, including a new crush tube and the DEA blocks. Parameters defined within the system integrated finite element model were determined from these tests. The objective of this paper is to summarize the finite element models developed and analyses performed, beginning with pre-test and continuing through post test validation.

Integrating Systems Health Management with Adaptive Controls for a Utility-Scale Wind Turbine

NASA Technical Reports Server (NTRS)

Frost, Susan A.; Goebel, Kai; Trinh, Khanh V.; Balas, Mark J.; Frost, Alan M.

2011-01-01

Increasing turbine up-time and reducing maintenance costs are key technology drivers for wind turbine operators. Components within wind turbines are subject to considerable stresses due to unpredictable environmental conditions resulting from rapidly changing local dynamics. Systems health management has the aim to assess the state-of-health of components within a wind turbine, to estimate remaining life, and to aid in autonomous decision-making to minimize damage. Advanced adaptive controls can provide the mechanism to enable optimized operations that also provide the enabling technology for Systems Health Management goals. The work reported herein explores the integration of condition monitoring of wind turbine blades with contingency management and adaptive controls. Results are demonstrated using a high fidelity simulator of a utility-scale wind turbine.

Entropy, pumped-storage and energy system finance

NASA Astrophysics Data System (ADS)

Karakatsanis, Georgios

2015-04-01

Pumped-storage holds a key role for integrating renewable energy units with non-renewable fuel plants into large-scale energy systems of electricity output. An emerging issue is the development of financial engineering models with physical basis to systematically fund energy system efficiency improvements across its operation. A fundamental physically-based economic concept is the Scarcity Rent; which concerns the pricing of a natural resource's scarcity. Specifically, the scarcity rent comprises a fraction of a depleting resource's full price and accumulates to fund its more efficient future use. In an integrated energy system, scarcity rents derive from various resources and can be deposited to a pooled fund to finance the energy system's overall efficiency increase; allowing it to benefit from economies of scale. With pumped-storage incorporated to the system, water upgrades to a hub resource, in which the scarcity rents of all connected energy sources are denominated to. However, as available water for electricity generation or storage is also limited, a scarcity rent upon it is also imposed. It is suggested that scarcity rent generation is reducible to three (3) main factors, incorporating uncertainty: (1) water's natural renewability, (2) the energy system's intermittent components and (3) base-load prediction deviations from actual loads. For that purpose, the concept of entropy is used in order to measure the energy system's overall uncertainty; hence pumped-storage intensity requirements and generated water scarcity rents. Keywords: pumped-storage, integration, energy systems, financial engineering, physical basis, Scarcity Rent, pooled fund, economies of scale, hub resource, uncertainty, entropy Acknowledgement: This research was funded by the Greek General Secretariat for Research and Technology through the research project Combined REnewable Systems for Sustainable ENergy DevelOpment (CRESSENDO; grant number 5145)

A Land System representation for global assessments and land-use modeling.

PubMed

van Asselen, Sanneke; Verburg, Peter H

2012-10-01

Current global scale land-change models used for integrated assessments and climate modeling are based on classifications of land cover. However, land-use management intensity and livestock keeping are also important aspects of land use, and are an integrated part of land systems. This article aims to classify, map, and to characterize Land Systems (LS) at a global scale and analyze the spatial determinants of these systems. Besides proposing such a classification, the article tests if global assessments can be based on globally uniform allocation rules. Land cover, livestock, and agricultural intensity data are used to map LS using a hierarchical classification method. Logistic regressions are used to analyze variation in spatial determinants of LS. The analysis of the spatial determinants of LS indicates strong associations between LS and a range of socioeconomic and biophysical indicators of human-environment interactions. The set of identified spatial determinants of a LS differs among regions and scales, especially for (mosaic) cropland systems, grassland systems with livestock, and settlements. (Semi-)Natural LS have more similar spatial determinants across regions and scales. Using LS in global models is expected to result in a more accurate representation of land use capturing important aspects of land systems and land architecture: the variation in land cover and the link between land-use intensity and landscape composition. Because the set of most important spatial determinants of LS varies among regions and scales, land-change models that include the human drivers of land change are best parameterized at sub-global level, where similar biophysical, socioeconomic and cultural conditions prevail in the specific regions. © 2012 Blackwell Publishing Ltd.

Engineering challenges for instrumenting and controlling integrated organ-on-chip systems.

PubMed

Wikswo, John P; Block, Frank E; Cliffel, David E; Goodwin, Cody R; Marasco, Christina C; Markov, Dmitry A; McLean, David L; McLean, John A; McKenzie, Jennifer R; Reiserer, Ronald S; Samson, Philip C; Schaffer, David K; Seale, Kevin T; Sherrod, Stacy D

2013-03-01

The sophistication and success of recently reported microfabricated organs-on-chips and human organ constructs have made it possible to design scaled and interconnected organ systems that may significantly augment the current drug development pipeline and lead to advances in systems biology. Physiologically realistic live microHuman (μHu) and milliHuman (mHu) systems operating for weeks to months present exciting and important engineering challenges such as determining the appropriate size for each organ to ensure appropriate relative organ functional activity, achieving appropriate cell density, providing the requisite universal perfusion media, sensing the breadth of physiological responses, and maintaining stable control of the entire system, while maintaining fluid scaling that consists of ~5 mL for the mHu and ~5 μL for the μHu. We believe that successful mHu and μHu systems for drug development and systems biology will require low-volume microdevices that support chemical signaling, microfabricated pumps, valves and microformulators, automated optical microscopy, electrochemical sensors for rapid metabolic assessment, ion mobility-mass spectrometry for real-time molecular analysis, advanced bioinformatics, and machine learning algorithms for automated model inference and integrated electronic control. Toward this goal, we are building functional prototype components and are working toward top-down system integration.

Low Density Materials

DTIC Science & Technology

2012-03-09

materials structures across scales for design of engineered systems ODISSEI: Origami Design for Integration of Self-assembling Systems for...AGENCIES Origami Engineering US-India Tunable Materials Forum US-AFRICA Initiative Reliance 21 Board Materials and Processing COI 29 DISTRIBUTION A

Correlation of ground tests and analyses of a dynamically scaled Space Station model configuration

NASA Technical Reports Server (NTRS)

Javeed, Mehzad; Edighoffer, Harold H.; Mcgowan, Paul E.

1993-01-01

Verification of analytical models through correlation with ground test results of a complex space truss structure is demonstrated. A multi-component, dynamically scaled space station model configuration is the focus structure for this work. Previously established test/analysis correlation procedures are used to develop improved component analytical models. Integrated system analytical models, consisting of updated component analytical models, are compared with modal test results to establish the accuracy of system-level dynamic predictions. Design sensitivity model updating methods are shown to be effective for providing improved component analytical models. Also, the effects of component model accuracy and interface modeling fidelity on the accuracy of integrated model predictions is examined.

Performance Evaluation of Engineered Structured Sorbents for Atmosphere Revitalization Systems On Board Crewed Space Vehicles and Habitats

NASA Technical Reports Server (NTRS)

Howard, David F.; Perry, Jay L.; Knox, James C.; Junaedi, Christian; Roychoudhury, Subir

2011-01-01

Engineered structured (ES) sorbents are being developed to meet the technical challenges of future crewed space exploration missions. ES sorbents offer the inherent performance and safety attributes of zeolite and other physical adsorbents but with greater structural integrity and process control to improve durability and efficiency over packed beds. ES sorbent techniques that are explored include thermally linked and pressure-swing adsorption beds for water-save dehumidification and sorbent-coated metal meshes for residual drying, trace contaminant control, and carbon dioxide control. Results from sub-scale performance evaluations of a thermally linked pressure-swing adsorbent bed and an integrated sub-scale ES sorbent system are discussed.

The Numerical Propulsion System Simulation: An Overview

NASA Technical Reports Server (NTRS)

Lytle, John K.

2000-01-01

Advances in computational technology and in physics-based modeling are making large-scale, detailed simulations of complex systems possible within the design environment. For example, the integration of computing, communications, and aerodynamics has reduced the time required to analyze major propulsion system components from days and weeks to minutes and hours. This breakthrough has enabled the detailed simulation of major propulsion system components to become a routine part of designing systems, providing the designer with critical information about the components early in the design process. This paper describes the development of the numerical propulsion system simulation (NPSS), a modular and extensible framework for the integration of multicomponent and multidisciplinary analysis tools using geographically distributed resources such as computing platforms, data bases, and people. The analysis is currently focused on large-scale modeling of complete aircraft engines. This will provide the product developer with a "virtual wind tunnel" that will reduce the number of hardware builds and tests required during the development of advanced aerospace propulsion systems.

High throughput screening of particle conditioning operations: I. System design and method development.

PubMed

Noyes, Aaron; Huffman, Ben; Godavarti, Ranga; Titchener-Hooker, Nigel; Coffman, Jonathan; Sunasara, Khurram; Mukhopadhyay, Tarit

2015-08-01

The biotech industry is under increasing pressure to decrease both time to market and development costs. Simultaneously, regulators are expecting increased process understanding. High throughput process development (HTPD) employs small volumes, parallel processing, and high throughput analytics to reduce development costs and speed the development of novel therapeutics. As such, HTPD is increasingly viewed as integral to improving developmental productivity and deepening process understanding. Particle conditioning steps such as precipitation and flocculation may be used to aid the recovery and purification of biological products. In this first part of two articles, we describe an ultra scale-down system (USD) for high throughput particle conditioning (HTPC) composed of off-the-shelf components. The apparatus is comprised of a temperature-controlled microplate with magnetically driven stirrers and integrated with a Tecan liquid handling robot. With this system, 96 individual reaction conditions can be evaluated in parallel, including downstream centrifugal clarification. A comprehensive suite of high throughput analytics enables measurement of product titer, product quality, impurity clearance, clarification efficiency, and particle characterization. HTPC at the 1 mL scale was evaluated with fermentation broth containing a vaccine polysaccharide. The response profile was compared with the Pilot-scale performance of a non-geometrically similar, 3 L reactor. An engineering characterization of the reactors and scale-up context examines theoretical considerations for comparing this USD system with larger scale stirred reactors. In the second paper, we will explore application of this system to industrially relevant vaccines and test different scale-up heuristics. © 2015 Wiley Periodicals, Inc.

Transmission system protection screening for integration of offshore wind power plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sajadi, A.; Strezoski, L.; Clark, K.

This paper develops an efficient methodology for protection screening of large-scale transmission systems as part of the planning studies for the integration of offshore wind power plants into the power grid. This methodology avails to determine whether any upgrades are required to the protection system. The uncertainty is considered in form of variability of the power generation by offshore wind power plant. This paper uses the integration of a 1000 MW offshore wind power plant operating in Lake Erie into the FirstEnergy/PJM service territory as a case study. This study uses a realistic model of a 63,000-bus test system thatmore » represents the U.S. Eastern Interconnection.« less

Transmission system protection screening for integration of offshore wind power plants

DOE PAGES

Sajadi, A.; Strezoski, L.; Clark, K.; ...

2018-02-21

This paper develops an efficient methodology for protection screening of large-scale transmission systems as part of the planning studies for the integration of offshore wind power plants into the power grid. This methodology avails to determine whether any upgrades are required to the protection system. The uncertainty is considered in form of variability of the power generation by offshore wind power plant. This paper uses the integration of a 1000 MW offshore wind power plant operating in Lake Erie into the FirstEnergy/PJM service territory as a case study. This study uses a realistic model of a 63,000-bus test system thatmore » represents the U.S. Eastern Interconnection.« less

Control Data ICEM: A vendors IPAD-like system

NASA Technical Reports Server (NTRS)

Feldman, H. D.

1984-01-01

The IPAD program's goal which was to integrate aerospace applications used in support of the engineering design process is discussed. It is still the key goal, and has evolved into a design centered around the use of data base management, networking, and global user executive technology. An integrated CAD/CAM system modeled in part after the IPAD program and containing elements of the program's goals was developed. The integrated computer aided engineering and manufacturing (ICEM) program started with the acquisition of AD-2000 and Synthavision. The AD-2000 has evolved to a production geometry creation and drafting system which is called CD/2000. Synthavision has grown to be a full scale 3-dimensional modeling system, the ICEM Modeler.

Evolution of natural history information in the 21st century – developing an integrated framework for biological and geographical data

USGS Publications Warehouse

Reusser, Deborah A.; Lee, Henry

2011-01-01

Threats to marine and estuarine species operate over many spatial scales, from nutrient enrichment at the watershed/estuarine scale to invasive species and climate change at regional and global scales. To help address research questions across these scales, we provide here a standardized framework for a biogeographical information system containing queriable biological data that allows extraction of information on multiple species, across a variety of spatial scales based on species distributions, natural history attributes and habitat requirements. As scientists shift from research on localized impacts on individual species to regional and global scale threats, macroecological approaches of studying multiple species over broad geographical areas are becoming increasingly important. The standardized framework described here for capturing and integrating biological and geographical data is a critical first step towards addressing these macroecological questions and we urge organizations capturing biogeoinformatics data to consider adopting this framework.

Develop and test fuel cell powered on-site integrated total energy systems. Phase 3: Full-scale power plant development

NASA Technical Reports Server (NTRS)

Feigenbaum, H.; Kaufman, A.; Wang, C. L.; Werth, J.; Whelan, J. A.

1983-01-01

Operating experience with a 5kW methanol-air integrated system is described. On-going test results for a 24-cell, two-sq ft (4kW) stack are reported. The main activity for this stack is currently the evaluation of developmental non-metalic cooling plates. Single-cell test results are presented for a promising developmental cathode catalyst.

Implementation of a large-scale hospital information infrastructure for multi-unit health-care services.

PubMed

Yoo, Sun K; Kim, Dong Keun; Kim, Jung C; Park, Youn Jung; Chang, Byung Chul

2008-01-01

With the increase in demand for high quality medical services, the need for an innovative hospital information system has become essential. An improved system has been implemented in all hospital units of the Yonsei University Health System. Interoperability between multi-units required appropriate hardware infrastructure and software architecture. This large-scale hospital information system encompassed PACS (Picture Archiving and Communications Systems), EMR (Electronic Medical Records) and ERP (Enterprise Resource Planning). It involved two tertiary hospitals and 50 community hospitals. The monthly data production rate by the integrated hospital information system is about 1.8 TByte and the total quantity of data produced so far is about 60 TByte. Large scale information exchange and sharing will be particularly useful for telemedicine applications.

Multidimensional quantum entanglement with large-scale integrated optics.

PubMed

Wang, Jianwei; Paesani, Stefano; Ding, Yunhong; Santagati, Raffaele; Skrzypczyk, Paul; Salavrakos, Alexia; Tura, Jordi; Augusiak, Remigiusz; Mančinska, Laura; Bacco, Davide; Bonneau, Damien; Silverstone, Joshua W; Gong, Qihuang; Acín, Antonio; Rottwitt, Karsten; Oxenløwe, Leif K; O'Brien, Jeremy L; Laing, Anthony; Thompson, Mark G

2018-04-20

The ability to control multidimensional quantum systems is central to the development of advanced quantum technologies. We demonstrate a multidimensional integrated quantum photonic platform able to generate, control, and analyze high-dimensional entanglement. A programmable bipartite entangled system is realized with dimensions up to 15 × 15 on a large-scale silicon photonics quantum circuit. The device integrates more than 550 photonic components on a single chip, including 16 identical photon-pair sources. We verify the high precision, generality, and controllability of our multidimensional technology, and further exploit these abilities to demonstrate previously unexplored quantum applications, such as quantum randomness expansion and self-testing on multidimensional states. Our work provides an experimental platform for the development of multidimensional quantum technologies. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Maximum Temperature Detection System for Integrated Circuits

NASA Astrophysics Data System (ADS)

Frankiewicz, Maciej; Kos, Andrzej

2015-03-01

The paper describes structure and measurement results of the system detecting present maximum temperature on the surface of an integrated circuit. The system consists of the set of proportional to absolute temperature sensors, temperature processing path and a digital part designed in VHDL. Analogue parts of the circuit where designed with full-custom technique. The system is a part of temperature-controlled oscillator circuit - a power management system based on dynamic frequency scaling method. The oscillator cooperates with microprocessor dedicated for thermal experiments. The whole system is implemented in UMC CMOS 0.18 μm (1.8 V) technology.

LARGE SCALE DISASTER ANALYSIS AND MANAGEMENT: SYSTEM LEVEL STUDY ON AN INTEGRATED MODEL

EPA Science Inventory

The increasing intensity and scale of human activity across the globe leading to severe depletion and deterioration of the Earth's natural resources has meant that sustainability has emerged as a new paradigm of analysis and management. Sustainability, conceptually defined by the...

Fine-scale topography in sensory systems: insights from Drosophila and vertebrates

PubMed Central

Kaneko, Takuya; Ye, Bing

2015-01-01

To encode the positions of sensory stimuli, sensory circuits form topographic maps in the central nervous system through specific point-to-point connections between pre- and post-synaptic neurons. In vertebrate visual systems, the establishment of topographic maps involves the formation of a coarse topography followed by that of fine-scale topography that distinguishes the axon terminals of neighboring neurons. It is known that intrinsic differences in the form of broad gradients of guidance molecules instruct coarse topography while neuronal activity is required for fine-scale topography. On the other hand, studies in the Drosophila visual system have shown that intrinsic differences in cell adhesion among the axon terminals of neighboring neurons instruct the fine-scale topography. Recent studies on activity-dependent topography in the Drosophila somatosensory system have revealed a role of neuronal activity in creating molecular differences among sensory neurons for establishing fine-scale topography, implicating a conserved principle. Here we review the findings in both Drosophila and vertebrates and propose an integrated model for fine-scale topography. PMID:26091779

Fine-scale topography in sensory systems: insights from Drosophila and vertebrates.

PubMed

Kaneko, Takuya; Ye, Bing

2015-09-01

To encode the positions of sensory stimuli, sensory circuits form topographic maps in the central nervous system through specific point-to-point connections between pre- and postsynaptic neurons. In vertebrate visual systems, the establishment of topographic maps involves the formation of a coarse topography followed by that of fine-scale topography that distinguishes the axon terminals of neighboring neurons. It is known that intrinsic differences in the form of broad gradients of guidance molecules instruct coarse topography while neuronal activity is required for fine-scale topography. On the other hand, studies in the Drosophila visual system have shown that intrinsic differences in cell adhesion among the axon terminals of neighboring neurons instruct the fine-scale topography. Recent studies on activity-dependent topography in the Drosophila somatosensory system have revealed a role of neuronal activity in creating molecular differences among sensory neurons for establishing fine-scale topography, implicating a conserved principle. Here we review the findings in both Drosophila and vertebrates and propose an integrated model for fine-scale topography.

Efficient data management in a large-scale epidemiology research project.

PubMed

Meyer, Jens; Ostrzinski, Stefan; Fredrich, Daniel; Havemann, Christoph; Krafczyk, Janina; Hoffmann, Wolfgang

2012-09-01

This article describes the concept of a "Central Data Management" (CDM) and its implementation within the large-scale population-based medical research project "Personalized Medicine". The CDM can be summarized as a conjunction of data capturing, data integration, data storage, data refinement, and data transfer. A wide spectrum of reliable "Extract Transform Load" (ETL) software for automatic integration of data as well as "electronic Case Report Forms" (eCRFs) was developed, in order to integrate decentralized and heterogeneously captured data. Due to the high sensitivity of the captured data, high system resource availability, data privacy, data security and quality assurance are of utmost importance. A complex data model was developed and implemented using an Oracle database in high availability cluster mode in order to integrate different types of participant-related data. Intelligent data capturing and storage mechanisms are improving the quality of data. Data privacy is ensured by a multi-layered role/right system for access control and de-identification of identifying data. A well defined backup process prevents data loss. Over the period of one and a half year, the CDM has captured a wide variety of data in the magnitude of approximately 5terabytes without experiencing any critical incidents of system breakdown or loss of data. The aim of this article is to demonstrate one possible way of establishing a Central Data Management in large-scale medical and epidemiological studies. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Deterministic radiative coupling of two semiconductor quantum dots to the optical mode of a photonic crystal nanocavity.

PubMed

Calic, M; Jarlov, C; Gallo, P; Dwir, B; Rudra, A; Kapon, E

2017-06-22

A system of two site-controlled semiconductor quantum dots (QDs) is deterministically integrated with a photonic crystal membrane nano-cavity. The two QDs are identified via their reproducible emission spectral features, and their coupling to the fundamental cavity mode is established by emission co-polarization and cavity feeding features. A theoretical model accounting for phonon interaction and pure dephasing reproduces the observed results and permits extraction of the light-matter coupling constant for this system. The demonstrated approach offers a platform for scaling up the integration of QD systems and nano-photonic elements for integrated quantum photonics applications.

Groundwater-fed irrigation impacts spatially distributed temporal scaling behavior of the natural system: a spatio-temporal framework for understanding water management impacts

NASA Astrophysics Data System (ADS)

Condon, Laura E.; Maxwell, Reed M.

2014-03-01

Regional scale water management analysis increasingly relies on integrated modeling tools. Much recent work has focused on groundwater-surface water interactions and feedbacks. However, to our knowledge, no study has explicitly considered impacts of management operations on the temporal dynamics of the natural system. Here, we simulate twenty years of hourly moisture dependent, groundwater-fed irrigation using a three-dimensional, fully integrated, hydrologic model (ParFlow-CLM). Results highlight interconnections between irrigation demand, groundwater oscillation frequency and latent heat flux variability not previously demonstrated. Additionally, the three-dimensional model used allows for novel consideration of spatial patterns in temporal dynamics. Latent heat flux and water table depth both display spatial organization in temporal scaling, an important finding given the spatial homogeneity and weak scaling observed in atmospheric forcings. Pumping and irrigation amplify high frequency (sub-annual) variability while attenuating low frequency (inter-annual) variability. Irrigation also intensifies scaling within irrigated areas, essentially increasing temporal memory in both the surface and the subsurface. These findings demonstrate management impacts that extend beyond traditional water balance considerations to the fundamental behavior of the system itself. This is an important step to better understanding groundwater’s role as a buffer for natural variability and the impact that water management has on this capacity.

Intelligent Facades for High Performance Green Buildings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dyson, Anna

Progress Towards Net-Zero and Net-Positive-Energy Commercial Buildings and Urban Districts Through Intelligent Building Envelope Strategies Previous research and development of intelligent facades systems has been limited in their contribution towards national goals for achieving on-site net zero buildings, because this R&D has failed to couple the many qualitative requirements of building envelopes such as the provision of daylighting, access to exterior views, satisfying aesthetic and cultural characteristics, with the quantitative metrics of energy harvesting, storage and redistribution. To achieve energy self-sufficiency from on-site solar resources, building envelopes can and must address this gamut of concerns simultaneously. With this project, wemore » have undertaken a high-performance building integrated combined-heat and power concentrating photovoltaic system with high temperature thermal capture, storage and transport towards multiple applications (BICPV/T). The critical contribution we are offering with the Integrated Concentrating Solar Façade (ICSF) is conceived to improve daylighting quality for improved health of occupants and mitigate solar heat gain while maximally capturing and transferring onsite solar energy. The ICSF accomplishes this multi-functionality by intercepting only the direct-normal component of solar energy (which is responsible for elevated cooling loads) thereby transforming a previously problematic source of energy into a high quality resource that can be applied to building demands such as heating, cooling, dehumidification, domestic hot water, and possible further augmentation of electrical generation through organic Rankine cycles. With the ICSF technology, our team is addressing the global challenge in transitioning commercial and residential building stock towards on-site clean energy self-sufficiency, by fully integrating innovative environmental control systems strategies within an intelligent and responsively dynamic building envelope. The advantage of being able to use the entire solar spectrum for active and passive benefits, along with the potential savings of avoiding transmission losses through direct current (DC) transfer to all buildings systems directly from the site of solar conversion, gives the system a compounded economic viability within the commercial and institutional building markets. With a team that spans multiple stakeholders across disparate industries, from CPV to A&E partners that are responsible for the design and development of District and Regional Scale Urban Development, this project demonstrates that integrating utility-scale high efficiency CPV installations with urban and suburban environments is both viable and desirable within the marketplace. The historical schism between utility scale CPV and BIPV has been one of differing scale and cultures. There is no technical reason why utility-scale CPV cannot be located within urban embedded district scale sites of energy harvesting. New models for leasing large areas of district scale roofs and facades are emerging, such that the model for utility scale energy harvesting can be reconciled to commercial and public scale building sites and campuses. This consortium is designed to unite utility scale solar harvesting into building applications for smart grid development.« less

Integration of Available and New Technologies to Raise Student Understanding and Engagement

ERIC Educational Resources Information Center

Souza, Joanne; Bingham, Paul M.

2006-01-01

We integrate available and new technologies to strongly enhance student engagement in upper division undergraduate courses on human evolution and history. First, we use peer-mentored discussion groups through the Blackboard system--appropriately scaled, constructed, and incentivized. These allow day-to-day monitoring of student understanding.…

Individualization for Education at Scale: MIIC Design and Preliminary Evaluation

ERIC Educational Resources Information Center

Brinton, Christopher G.; Rill, Ruediger; Ha, Sangtae; Chiang, Mung; Smith, Robert; Ju, William

2015-01-01

We present the design, implementation, and preliminary evaluation of our Adaptive Educational System (AES): the Mobile Integrated and Individualized Course (MIIC). MIIC is a platform for personalized course delivery which integrates lecture videos, text, assessments, and social learning into a mobile native app, and collects clickstream-level…

Strategic Enterprise Resource Planning for Global Supply Chain Competitiveness

ERIC Educational Resources Information Center

Nageswararao, A. V.; Sahu, Dasarathi; Mohan, V. Krishna

2011-01-01

Strategic Enterprise Resource planning (SERP) systems are networked and integrated information mechanisms which are developed to achieve competitive advantage for organizations operating in global scale. It plays a vital role in Integrating various stake holders and channel partners involved in day to day operations. In the present Globalized…

Awareness and implementation of the 2000 United States public health service tobacco dependence treatment guideline in a public hospital system.

PubMed

Moody-Thomas, Sarah; Horswell, Ronald; Celestin, Michael D; Dellinger, Amy B; Kaiser, Michael; Butler, Michael

2011-04-01

The 2000 United States Public Health Service (USPHS) clinical practice guideline, "Treating Tobacco Use and Dependence," recommends systems interventions to integrate the treatment of tobacco into routine health care. The Tobacco Control Initiative employed a systems approach to integrate evidence-based treatment for tobacco use into patient care practices in Louisiana's safety net health care system. The purpose of this study was to assess changes in awareness and implementation of the USPHS clinical practice guideline. Surveys were administered to a purposive sample of hospital personnel from key departments in the Louisiana State University system of public hospitals in 2003 (n = 24) and 2007 (n = 44). Perceptions of implementation success improved for 50 of 59 distinct survey items. Rasch scaling was used to assess overall (scaled) change and showed substantial improvement from 2003 to 2007 (P < 0.001). Survey items also were grouped into 6 logical key concept sets. Improvement occurred in perceptions for all 6 key concepts; however, not uniformly. Results of the 2003 and 2007 surveys illustrate the potential effectiveness of using a systems approach to integrate the assessment and treatment of tobacco use into routine care practices in a public health care delivery system that serves medically vulnerable populations.

Research undertaken and proposed directions for the coming year of the Information System Research Group

NASA Technical Reports Server (NTRS)

Estes, J. E.; Star, J. L.

1986-01-01

The basic understanding of the role of information systems technologies and artificial intelligence techniques in the integration, manipulation, and analysis of remotely sensed data for global scale studies is examined.

Integrating Climate and Risk-Informed Science to Support Critical Decisions

ScienceCinema

None

2018-01-16

The PNNL Environmental Health and Remediation Sector stewards several decision support capabilities to integrate climate- and risk-informed science to support critical decisions. Utilizing our expertise in risk and decision analysis, integrated Earth systems modeling, and remote sensing and geoinformatics, PNNL is influencing the way science informs high level decisions at national, regional and local scales to protect and preserve our most critical assets.

Integrating Climate and Risk-Informed Science to Support Critical Decisions

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2016-07-27

The PNNL Environmental Health and Remediation Sector stewards several decision support capabilities to integrate climate- and risk-informed science to support critical decisions. Utilizing our expertise in risk and decision analysis, integrated Earth systems modeling, and remote sensing and geoinformatics, PNNL is influencing the way science informs high level decisions at national, regional and local scales to protect and preserve our most critical assets.

Ultrafast optical ranging using microresonator soliton frequency combs

NASA Astrophysics Data System (ADS)

Trocha, P.; Karpov, M.; Ganin, D.; Pfeiffer, M. H. P.; Kordts, A.; Wolf, S.; Krockenberger, J.; Marin-Palomo, P.; Weimann, C.; Randel, S.; Freude, W.; Kippenberg, T. J.; Koos, C.

2018-02-01

Light detection and ranging is widely used in science and industry. Over the past decade, optical frequency combs were shown to offer advantages in optical ranging, enabling fast distance acquisition with high accuracy. Driven by emerging high-volume applications such as industrial sensing, drone navigation, or autonomous driving, there is now a growing demand for compact ranging systems. Here, we show that soliton Kerr comb generation in integrated silicon nitride microresonators provides a route to high-performance chip-scale ranging systems. We demonstrate dual-comb distance measurements with Allan deviations down to 12 nanometers at averaging times of 13 microseconds along with ultrafast ranging at acquisition rates of 100 megahertz, allowing for in-flight sampling of gun projectiles moving at 150 meters per second. Combining integrated soliton-comb ranging systems with chip-scale nanophotonic phased arrays could enable compact ultrafast ranging systems for emerging mass applications.

Data Integration: Charting a Path Forward to 2035

DTIC Science & Technology

2011-02-14

New York, NY: Gotham Books, 2004. Seligman , Len. Mitre Corporation, e-mail interview, 6 Dec 2010. Singer, P.W. Wired for War: The Robotics...articles.aspx (accessed 4 Dec 2010). Ultra-Large-Scale Systems: The Software Challenge of the Future. Study lead Linda Northrup. Pittsburgh, PA: Carnegie...Virtualization?‖ 1. 41 Ultra-Large-Scale Systems: The Software Challenge of the Future. Study lead Linda Northrup. Pittsburgh, PA: Carnegie Mellon Software

A Programmable and Configurable Mixed-Mode FPAA SoC

DTIC Science & Technology

2016-03-17

A Programmable and Configurable Mixed-Mode FPAA SoC Sahil Shah, Sihwan Kim, Farhan Adil, Jennifer Hasler, Suma George, Michelle Collins, Richard...Abstract: The authors present a Floating-Gate based, System-On-Chip large-scale Field- Programmable Analog Array IC that integrates divergent concepts...Floating-Gate, SoC, Command Word Classification This paper presents a Floating-Gate (FG) based, System- On-Chip (SoC) large-scale Field- Programmable

Hierarchical Engine for Large-scale Infrastructure Co-Simulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

2017-04-24

HELICS is designed to support very-large-scale (100,000+ federates) cosimulations with off-the-shelf power-system, communication, market, and end-use tools. Other key features include cross platform operating system support, the integration of both event driven (e.g., packetized communication) and time-series (e.g., power flow) simulations, and the ability to co-iterate among federates to ensure physical model convergence at each time step.

Overview of the NCC

NASA Technical Reports Server (NTRS)

Liu, Nan-Suey

2001-01-01

A multi-disciplinary design/analysis tool for combustion systems is critical for optimizing the low-emission, high-performance combustor design process. Based on discussions between then NASA Lewis Research Center and the jet engine companies, an industry-government team was formed in early 1995 to develop the National Combustion Code (NCC), which is an integrated system of computer codes for the design and analysis of combustion systems. NCC has advanced features that address the need to meet designer's requirements such as "assured accuracy", "fast turnaround", and "acceptable cost". The NCC development team is comprised of Allison Engine Company (Allison), CFD Research Corporation (CFDRC), GE Aircraft Engines (GEAE), NASA Glenn Research Center (LeRC), and Pratt & Whitney (P&W). The "unstructured mesh" capability and "parallel computing" are fundamental features of NCC from its inception. The NCC system is composed of a set of "elements" which includes grid generator, main flow solver, turbulence module, turbulence and chemistry interaction module, chemistry module, spray module, radiation heat transfer module, data visualization module, and a post-processor for evaluating engine performance parameters. Each element may have contributions from several team members. Such a multi-source multi-element system needs to be integrated in a way that facilitates inter-module data communication, flexibility in module selection, and ease of integration. The development of the NCC beta version was essentially completed in June 1998. Technical details of the NCC elements are given in the Reference List. Elements such as the baseline flow solver, turbulence module, and the chemistry module, have been extensively validated; and their parallel performance on large-scale parallel systems has been evaluated and optimized. However the scalar PDF module and the Spray module, as well as their coupling with the baseline flow solver, were developed in a small-scale distributed computing environment. As a result, the validation of the NCC beta version as a whole was quite limited. Current effort has been focused on the validation of the integrated code and the evaluation/optimization of its overall performance on large-scale parallel systems.

Validating a Geographical Image Retrieval System.

ERIC Educational Resources Information Center

Zhu, Bin; Chen, Hsinchun

2000-01-01

Summarizes a prototype geographical image retrieval system that demonstrates how to integrate image processing and information analysis techniques to support large-scale content-based image retrieval. Describes an experiment to validate the performance of this image retrieval system against that of human subjects by examining similarity analysis…

Parameter Sweep and Optimization of Loosely Coupled Simulations Using the DAKOTA Toolkit

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elwasif, Wael R; Bernholdt, David E; Pannala, Sreekanth

2012-01-01

The increasing availability of large scale computing capabilities has accelerated the development of high-fidelity coupled simulations. Such simulations typically involve the integration of models that implement various aspects of the complex phenomena under investigation. Coupled simulations are playing an integral role in fields such as climate modeling, earth systems modeling, rocket simulations, computational chemistry, fusion research, and many other computational fields. Model coupling provides scientists with systematic ways to virtually explore the physical, mathematical, and computational aspects of the problem. Such exploration is rarely done using a single execution of a simulation, but rather by aggregating the results from manymore » simulation runs that, together, serve to bring to light novel knowledge about the system under investigation. Furthermore, it is often the case (particularly in engineering disciplines) that the study of the underlying system takes the form of an optimization regime, where the control parameter space is explored to optimize an objective functions that captures system realizability, cost, performance, or a combination thereof. Novel and flexible frameworks that facilitate the integration of the disparate models into a holistic simulation are used to perform this research, while making efficient use of the available computational resources. In this paper, we describe the integration of the DAKOTA optimization and parameter sweep toolkit with the Integrated Plasma Simulator (IPS), a component-based framework for loosely coupled simulations. The integration allows DAKOTA to exploit the internal task and resource management of the IPS to dynamically instantiate simulation instances within a single IPS instance, allowing for greater control over the trade-off between efficiency of resource utilization and time to completion. We present a case study showing the use of the combined DAKOTA-IPS system to aid in the design of a lithium ion battery (LIB) cell, by studying a coupled system involving the electrochemistry and ion transport at the lower length scales and thermal energy transport at the device scales. The DAKOTA-IPS system provides a flexible tool for use in optimization and parameter sweep studies involving loosely coupled simulations that is suitable for use in situations where changes to the constituent components in the coupled simulation are impractical due to intellectual property or code heritage issues.« less

Computational singular perturbation analysis of stochastic chemical systems with stiffness

DOE PAGES

Wang, Lijin; Han, Xiaoying; Cao, Yanzhao; ...

2017-01-25

Computational singular perturbation (CSP) is a useful method for analysis, reduction, and time integration of stiff ordinary differential equation systems. It has found dominant utility, in particular, in chemical reaction systems with a large range of time scales at continuum and deterministic level. On the other hand, CSP is not directly applicable to chemical reaction systems at micro or meso-scale, where stochasticity plays an non-negligible role and thus has to be taken into account. In this work we develop a novel stochastic computational singular perturbation (SCSP) analysis and time integration framework, and associated algorithm, that can be used to notmore » only construct accurately and efficiently the numerical solutions to stiff stochastic chemical reaction systems, but also analyze the dynamics of the reduced stochastic reaction systems. Furthermore, the algorithm is illustrated by an application to a benchmark stochastic differential equation model, and numerical experiments are carried out to demonstrate the effectiveness of the construction.« less

Bringing the CMS distributed computing system into scalable operations

NASA Astrophysics Data System (ADS)

Belforte, S.; Fanfani, A.; Fisk, I.; Flix, J.; Hernández, J. M.; Kress, T.; Letts, J.; Magini, N.; Miccio, V.; Sciabà, A.

2010-04-01

Establishing efficient and scalable operations of the CMS distributed computing system critically relies on the proper integration, commissioning and scale testing of the data and workload management tools, the various computing workflows and the underlying computing infrastructure, located at more than 50 computing centres worldwide and interconnected by the Worldwide LHC Computing Grid. Computing challenges periodically undertaken by CMS in the past years with increasing scale and complexity have revealed the need for a sustained effort on computing integration and commissioning activities. The Processing and Data Access (PADA) Task Force was established at the beginning of 2008 within the CMS Computing Program with the mandate of validating the infrastructure for organized processing and user analysis including the sites and the workload and data management tools, validating the distributed production system by performing functionality, reliability and scale tests, helping sites to commission, configure and optimize the networking and storage through scale testing data transfers and data processing, and improving the efficiency of accessing data across the CMS computing system from global transfers to local access. This contribution reports on the tools and procedures developed by CMS for computing commissioning and scale testing as well as the improvements accomplished towards efficient, reliable and scalable computing operations. The activities include the development and operation of load generators for job submission and data transfers with the aim of stressing the experiment and Grid data management and workload management systems, site commissioning procedures and tools to monitor and improve site availability and reliability, as well as activities targeted to the commissioning of the distributed production, user analysis and monitoring systems.

Development and Verification of a Novel Robot-Integrated Fringe Projection 3D Scanning System for Large-Scale Metrology.

PubMed

Du, Hui; Chen, Xiaobo; Xi, Juntong; Yu, Chengyi; Zhao, Bao

2017-12-12

Large-scale surfaces are prevalent in advanced manufacturing industries, and 3D profilometry of these surfaces plays a pivotal role for quality control. This paper proposes a novel and flexible large-scale 3D scanning system assembled by combining a robot, a binocular structured light scanner and a laser tracker. The measurement principle and system construction of the integrated system are introduced. A mathematical model is established for the global data fusion. Subsequently, a robust method is introduced for the establishment of the end coordinate system. As for hand-eye calibration, the calibration ball is observed by the scanner and the laser tracker simultaneously. With this data, the hand-eye relationship is solved, and then an algorithm is built to get the transformation matrix between the end coordinate system and the world coordinate system. A validation experiment is designed to verify the proposed algorithms. Firstly, a hand-eye calibration experiment is implemented and the computation of the transformation matrix is done. Then a car body rear is measured 22 times in order to verify the global data fusion algorithm. The 3D shape of the rear is reconstructed successfully. To evaluate the precision of the proposed method, a metric tool is built and the results are presented.

The application of liquid air energy storage for large scale long duration solutions to grid balancing

NASA Astrophysics Data System (ADS)

Brett, Gareth; Barnett, Matthew

2014-12-01

Liquid Air Energy Storage (LAES) provides large scale, long duration energy storage at the point of demand in the 5 MW/20 MWh to 100 MW/1,000 MWh range. LAES combines mature components from the industrial gas and electricity industries assembled in a novel process and is one of the few storage technologies that can be delivered at large scale, with no geographical constraints. The system uses no exotic materials or scarce resources and all major components have a proven lifetime of 25+ years. The system can also integrate low grade waste heat to increase power output. Founded in 2005, Highview Power Storage, is a UK based developer of LAES. The company has taken the concept from academic analysis, through laboratory testing, and in 2011 commissioned the world's first fully integrated system at pilot plant scale (300 kW/2.5 MWh) hosted at SSE's (Scottish & Southern Energy) 80 MW Biomass Plant in Greater London which was partly funded by a Department of Energy and Climate Change (DECC) grant. Highview is now working with commercial customers to deploy multi MW commercial reference plants in the UK and abroad.

A novel land surface-hydrologic-sediment dynamics model for stream corridor conservation assessment and its first application

NASA Astrophysics Data System (ADS)

Smithgall, K.; Shen, C.; Langendoen, E. J.; Johnson, P. A.

2015-12-01

Nationally and in the Chesapeake Bay (CB), Stream Corridor restoration costs unsustainable amount of public resources, but decisions are often made with inadequate knowledge of regional-scale system behavior. Bank erosion is a significant issue relevant to sediment and nutrient pollution, aquatic and riparian habitat and stream health. Existing modeling effort either focuses only on reach-scale responses or overly simplifies the descriptions for bank failure mechanics. In this work we present a novel regional-scale processes model integrating hydrology, vegetation dynamics, hydraulics, bank mechanics and sediment transport, based on a coupling between Community Land Model, Process-based Adaptive Watershed Simulator and CONservational Channel Evolution and Pollutant Transport System (CLM + PAWS + CONCEPTS, CPC). We illustrate the feasibility of this modeling platform in a Valley and Ridge basin in Pennsylvania, USA, with channel geometry data collected in 2004 and 2014. The simulations are able to reproduce essential pattern of the observed trends. We study the causes of the noticeable evolution of a relocated channel and the hydrologic controls. Bridging processes on multiple scales, the CPC model creates a new, integrated system that may serve as a confluence point for inter-disciplinary research.

SSI/MSI/LSI/VLSI/ULSI.

ERIC Educational Resources Information Center

Alexander, George

1984-01-01

Discusses small-scale integrated (SSI), medium-scale integrated (MSI), large-scale integrated (LSI), very large-scale integrated (VLSI), and ultra large-scale integrated (ULSI) chips. The development and properties of these chips, uses of gallium arsenide, Josephson devices (two superconducting strips sandwiching a thin insulator), and future…

A Multi-Scale, Integrated Approach to Representing Watershed Systems

NASA Astrophysics Data System (ADS)

Ivanov, Valeriy; Kim, Jongho; Fatichi, Simone; Katopodes, Nikolaos

2014-05-01

Understanding and predicting process dynamics across a range of scales are fundamental challenges for basic hydrologic research and practical applications. This is particularly true when larger-spatial-scale processes, such as surface-subsurface flow and precipitation, need to be translated to fine space-time scale dynamics of processes, such as channel hydraulics and sediment transport, that are often of primary interest. Inferring characteristics of fine-scale processes from uncertain coarse-scale climate projection information poses additional challenges. We have developed an integrated model simulating hydrological processes, flow dynamics, erosion, and sediment transport, tRIBS+VEGGIE-FEaST. The model targets to take the advantage of the current generation of wealth of data representing watershed topography, vegetation, soil, and landuse, as well as to explore the hydrological effects of physical factors and their feedback mechanisms over a range of scales. We illustrate how the modeling system connects precipitation-hydrologic runoff partition process to the dynamics of flow, erosion, and sedimentation, and how the soil's substrate condition can impact the latter processes, resulting in a non-unique response. We further illustrate an approach to using downscaled climate change information with a process-based model to infer the moments of hydrologic variables in future climate conditions and explore the impact of climate information uncertainty.

Integrating a geographic information system, a scientific visualization system and an orographic precipitation model

USGS Publications Warehouse

Hay, L.; Knapp, L.

1996-01-01

Investigating natural, potential, and man-induced impacts on hydrological systems commonly requires complex modelling with overlapping data requirements, and massive amounts of one- to four-dimensional data at multiple scales and formats. Given the complexity of most hydrological studies, the requisite software infrastructure must incorporate many components including simulation modelling, spatial analysis and flexible, intuitive displays. There is a general requirement for a set of capabilities to support scientific analysis which, at this time, can only come from an integration of several software components. Integration of geographic information systems (GISs) and scientific visualization systems (SVSs) is a powerful technique for developing and analysing complex models. This paper describes the integration of an orographic precipitation model, a GIS and a SVS. The combination of these individual components provides a robust infrastructure which allows the scientist to work with the full dimensionality of the data and to examine the data in a more intuitive manner.

UK Environmental Prediction - integration and evaluation at the convective scale

NASA Astrophysics Data System (ADS)

Fallmann, Joachim; Lewis, Huw; Castillo, Juan Manuel; Pearson, David; Harris, Chris; Saulter, Andy; Bricheno, Lucy; Blyth, Eleanor

2016-04-01

Traditionally, the simulation of regional ocean, wave and atmosphere components of the Earth System have been considered separately, with some information on other components provided by means of boundary or forcing conditions. More recently, the potential value of a more integrated approach, as required for global climate and Earth System prediction, for regional short-term applications has begun to gain increasing research effort. In the UK, this activity is motivated by an understanding that accurate prediction and warning of the impacts of severe weather requires an integrated approach to forecasting. The substantial impacts on individuals, businesses and infrastructure of such events indicate a pressing need to understand better the value that might be delivered through more integrated environmental prediction. To address this need, the Met Office, NERC Centre for Ecology & Hydrology and NERC National Oceanography Centre have begun to develop the foundations of a coupled high resolution probabilistic forecast system for the UK at km-scale. This links together existing model components of the atmosphere, coastal ocean, land surface and hydrology. Our initial focus has been on a 2-year Prototype project to demonstrate the UK coupled prediction concept in research mode. This presentation will provide an update on UK environmental prediction activities. We will present the results from the initial implementation of an atmosphere-land-ocean coupled system, including a new eddy-permitting resolution ocean component, and discuss progress and initial results from further development to integrate wave interactions in this relatively high resolution system. We will discuss future directions and opportunities for collaboration in environmental prediction, and the challenges to realise the potential of integrated regional coupled forecasting for improving predictions and applications.

Integrability and Poisson Structures of Three Dimensional Dynamical Systems and Equations of Hydrodynamic Type

NASA Astrophysics Data System (ADS)

Gumral, Hasan

Poisson structure of completely integrable 3 dimensional dynamical systems can be defined in terms of an integrable 1-form. We take advantage of this fact and use the theory of foliations in discussing the geometrical structure underlying complete and partial integrability. We show that the Halphen system can be formulated in terms of a flat SL(2,R)-valued connection and belongs to a non-trivial Godbillon-Vey class. On the other hand, for the Euler top and a special case of 3-species Lotka-Volterra equations which are contained in the Halphen system as limiting cases, this structure degenerates into the form of globally integrable bi-Hamiltonian structures. The globally integrable bi-Hamiltonian case is a linear and the sl_2 structure is a quadratic unfolding of an integrable 1-form in 3 + 1 dimensions. We complete the discussion of the Hamiltonian structure of 2-component equations of hydrodynamic type by presenting the Hamiltonian operators for Euler's equation and a continuum limit of Toda lattice. We present further infinite sequences of conserved quantities for shallow water equations and show that their generalizations by Kodama admit bi-Hamiltonian structure. We present a simple way of constructing the second Hamiltonian operators for N-component equations admitting some scaling properties. The Kodama reduction of the dispersionless-Boussinesq equations and the Lax reduction of the Benney moment equations are shown to be equivalent by a symmetry transformation. They can be cast into the form of a triplet of conservation laws which enable us to recognize a non-trivial scaling symmetry. The resulting bi-Hamiltonian structure generates three infinite sequences of conserved densities.

St. Louis Initiative for Integrated Care Excellence (SLI(2)CE): integrated-collaborative care on a large scale model.

PubMed

Brawer, Peter A; Martielli, Richard; Pye, Patrice L; Manwaring, Jamie; Tierney, Anna

2010-06-01

The primary care health setting is in crisis. Increasing demand for services, with dwindling numbers of providers, has resulted in decreased access and decreased satisfaction for both patients and providers. Moreover, the overwhelming majority of primary care visits are for behavioral and mental health concerns rather than issues of a purely medical etiology. Integrated-collaborative models of health care delivery offer possible solutions to this crisis. The purpose of this article is to review the existing data available after 2 years of the St. Louis Initiative for Integrated Care Excellence; an example of integrated-collaborative care on a large scale model within a regional Veterans Affairs Health Care System. There is clear evidence that the SLI(2)CE initiative rather dramatically increased access to health care, and modified primary care practitioners' willingness to address mental health issues within the primary care setting. In addition, data suggests strong fidelity to a model of integrated-collaborative care which has been successful in the past. Integrated-collaborative care offers unique advantages to the traditional view and practice of medical care. Through careful implementation and practice, success is possible on a large scale model. PsycINFO Database Record (c) 2010 APA, all rights reserved.

Scaling theory of topological phase transitions

NASA Astrophysics Data System (ADS)

Chen, Wei

2016-02-01

Topologically ordered systems are characterized by topological invariants that are often calculated from the momentum space integration of a certain function that represents the curvature of the many-body state. The curvature function may be Berry curvature, Berry connection, or other quantities depending on the system. Akin to stretching a messy string to reveal the number of knots it contains, a scaling procedure is proposed for the curvature function in inversion symmetric systems, from which the topological phase transition can be identified from the flow of the driving energy parameters that control the topology (hopping, chemical potential, etc) under scaling. At an infinitesimal operation, one obtains the renormalization group (RG) equations for the driving energy parameters. A length scale defined from the curvature function near the gap-closing momentum is suggested to characterize the scale invariance at critical points and fixed points, and displays a universal critical behavior in a variety of systems examined.

The economic and social benefits of an aquaponic system for the integrated production of fish and water plants

NASA Astrophysics Data System (ADS)

Rizal, A.; Dhahiyat, Y.; Zahidah; Andriani, Y.; Handaka, A. A.; Sahidin, A.

2018-04-01

Aquaponics is an evolving closed-system food production technology that integrates recirculating aquaculture with hydroponics. In this paper we give a brief literature overview of the benefit aspects of aquaponics by discussing its social, environmental, and economic impacts in different potential settings. The technology might be applied to commercial or community based urban food production, industrial scale production in rural areas, small scale farming in developing countries or as systems for education and decoration inside buildings. We concluded that due to the different potential applications and settings for installing the technology, benefit impacts need to be considered separately and that due the complexity, communities, urban and rural infrastructure and policy settings, further research and data acquisition is needed to be able to assess all benefit aspects.

Ultrastable assembly and integration technology for ground- and space-based optical systems.

PubMed

Ressel, Simon; Gohlke, Martin; Rauen, Dominik; Schuldt, Thilo; Kronast, Wolfgang; Mescheder, Ulrich; Johann, Ulrich; Weise, Dennis; Braxmaier, Claus

2010-08-01

Optical metrology systems crucially rely on the dimensional stability of the optical path between their individual optical components. We present in this paper a novel adhesive bonding technology for setup of quasi-monolithic systems and compare selected characteristics to the well-established state-of-the-art technique of hydroxide-catalysis bonding. It is demonstrated that within the measurement resolution of our ultraprecise custom heterodyne interferometer, both techniques achieve an equivalent passive path length and tilt stability for time scales between 0.1 mHz and 1 Hz. Furthermore, the robustness of the adhesive bonds against mechanical and thermal inputs has been tested, making this new bonding technique in particular a potential option for interferometric applications in future space missions. The integration process itself is eased by long time scales for alignment, as well as short curing times.

The CELSS breadboard project: Plant production

NASA Technical Reports Server (NTRS)

Knott, William M.

1990-01-01

NASA's Breadboard Project for the Controlled Ecological Life Support System (CELSS) program is described. The simplified schematic of a CELSS is given. A modular approach is taken to building the CELSS Breadboard. Each module is researched in order to develop a data set for each one prior to its integration into the complete system. The data being obtained from the Biomass Production Module or the Biomass Production Chamber is examined. The other primary modules, food processing and resource recovery or waste management, are discussed briefly. The crew habitat module is not discussed. The primary goal of the Breadboard Project is to scale-up research data to an integrated system capable of supporting one person in order to establish feasibility for the development and operation of a CELSS. Breadboard is NASA's first attempt at developing a large scale CELSS.

Overview of ERA Integrated Technology Demonstration (ITD) 51A Ultra-High Bypass (UHB) Integration for Hybrid Wing Body (HWB)

NASA Technical Reports Server (NTRS)

Flamm, Jeffrey D.; James, Kevin D.; Bonet, John T.

2016-01-01

The NASA Environmentally Responsible Aircraft Project (ERA) was a ve year project broken into two phases. In phase II, high N+2 Technical Readiness Level demonstrations were grouped into Integrated Technology Demonstrations (ITD). This paper describes the work done on ITD-51A: the Vehicle Systems Integration, Engine Airframe Integration Demonstration. Refinement of a Hybrid Wing Body (HWB) aircraft from the possible candidates developed in ERA Phase I was continued. Scaled powered, and unpowered wind- tunnel testing, with and without acoustics, in the NASA LARC 14- by 22-foot Subsonic Tunnel, the NASA ARC Unitary Plan Wind Tunnel, and the 40- by 80-foot test section of the National Full-Scale Aerodynamics Complex (NFAC) in conjunction with very closely coupled Computational Fluid Dynamics was used to demonstrate the fuel burn and acoustic milestone targets of the ERA Project.

Analysis of DNA Sequences by an Optical Time-Integrating Correlator: Proposal

DTIC Science & Technology

1991-11-01

OF THE PROBLEM AND CURRENT TECHNOLOGY 2 3.0 TIME-INTEGRATING CORRELATOR 2 4.0 REPRESENTATIONS OF THE DNA BASES 8 5.0 DNA ANALYSIS STRATEGY 8 6.0... DNA bases where each base is represented by a 7-bits long pseudorandom sequence. 9 Figure 5: The flow of data in a DNA analysis system based on an...logarithmic scale and a linear scale. 15 x LIST OF TABLES PAGE Table 1: Short representations of the DNA bases where each base is represented by 7-bits

On the Path to SunShot. Emerging Issues and Challenges in Integrating Solar with the Distribution System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Palmintier, Bryan; Broderick, Robert; Mather, Barry

2016-05-01

This report analyzes distribution-integration challenges, solutions, and research needs in the context of distributed generation from PV (DGPV) deployment to date and the much higher levels of deployment expected with achievement of the U.S. Department of Energy's SunShot targets. Recent analyses have improved estimates of the DGPV hosting capacities of distribution systems. This report uses these results to statistically estimate the minimum DGPV hosting capacity for the contiguous United States using traditional inverters of approximately 170 GW without distribution system modifications. This hosting capacity roughly doubles if advanced inverters are used to manage local voltage and additional minor, low-cost changesmore » could further increase these levels substantially. Key to achieving these deployment levels at minimum cost is siting DGPV based on local hosting capacities, suggesting opportunities for regulatory, incentive, and interconnection innovation. Already, pre-computed hosting capacity is beginning to expedite DGPV interconnection requests and installations in select regions; however, realizing SunShot-scale deployment will require further improvements to DGPV interconnection processes, standards and codes, and compensation mechanisms so they embrace the contributions of DGPV to system-wide operations. SunShot-scale DGPV deployment will also require unprecedented coordination of the distribution and transmission systems. This includes harnessing DGPV's ability to relieve congestion and reduce system losses by generating closer to loads; minimizing system operating costs and reserve deployments through improved DGPV visibility; developing communication and control architectures that incorporate DGPV into system operations; providing frequency response, transient stability, and synthesized inertia with DGPV in the event of large-scale system disturbances; and potentially managing reactive power requirements due to large-scale deployment of advanced inverter functions. Finally, additional local and system-level value could be provided by integrating DGPV with energy storage and 'virtual storage,' which exploits improved management of electric vehicle charging, building energy systems, and other large loads. Together, continued innovation across this rich distribution landscape can enable the very-high deployment levels envisioned by SunShot.« less

7th Annual Systems Biology Symposium: Systems Biology and Engineering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galitski, Timothy P.

2008-04-01

Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology has been hosted by the Institute for Systems Biology in Seattle, Washington, since 2002. The annual two-day event gathers the most influential researchers transforming biology into an integrative discipline investingating complex systems. Engineering and application of new technology is a central element of systems biology. Genome-scale, or very small-scale, biological questions drive the enigneering of new technologies, which enable new modes of experimentation and computational analysis, leading to new biological insights and questions. Concepts and analytical methods in engineering aremore » now finding direct applications in biology. Therefore, the 2008 Symposium, funded in partnership with the Department of Energy, featured global leaders in "Systems Biology and Engineering."« less

A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology

PubMed Central

2011-01-01

Background Genome-scale metabolic reconstructions provide a biologically meaningful mechanistic basis for the genotype-phenotype relationship. The global human metabolic network, termed Recon 1, has recently been reconstructed allowing the systems analysis of human metabolic physiology and pathology. Utilizing high-throughput data, Recon 1 has recently been tailored to different cells and tissues, including the liver, kidney, brain, and alveolar macrophage. These models have shown utility in the study of systems medicine. However, no integrated analysis between human tissues has been done. Results To describe tissue-specific functions, Recon 1 was tailored to describe metabolism in three human cells: adipocytes, hepatocytes, and myocytes. These cell-specific networks were manually curated and validated based on known cellular metabolic functions. To study intercellular interactions, a novel multi-tissue type modeling approach was developed to integrate the metabolic functions for the three cell types, and subsequently used to simulate known integrated metabolic cycles. In addition, the multi-tissue model was used to study diabetes: a pathology with systemic properties. High-throughput data was integrated with the network to determine differential metabolic activity between obese and type II obese gastric bypass patients in a whole-body context. Conclusion The multi-tissue type modeling approach presented provides a platform to study integrated metabolic states. As more cell and tissue-specific models are released, it is critical to develop a framework in which to study their interdependencies. PMID:22041191

Canonical-ensemble extended Lagrangian Born-Oppenheimer molecular dynamics for the linear scaling density functional theory.

PubMed

Hirakawa, Teruo; Suzuki, Teppei; Bowler, David R; Miyazaki, Tsuyoshi

2017-10-11

We discuss the development and implementation of a constant temperature (NVT) molecular dynamics scheme that combines the Nosé-Hoover chain thermostat with the extended Lagrangian Born-Oppenheimer molecular dynamics (BOMD) scheme, using a linear scaling density functional theory (DFT) approach. An integration scheme for this canonical-ensemble extended Lagrangian BOMD is developed and discussed in the context of the Liouville operator formulation. Linear scaling DFT canonical-ensemble extended Lagrangian BOMD simulations are tested on bulk silicon and silicon carbide systems to evaluate our integration scheme. The results show that the conserved quantity remains stable with no systematic drift even in the presence of the thermostat.

Interactive graphical computer-aided design system

NASA Technical Reports Server (NTRS)

Edge, T. M.

1975-01-01

System is used for design, layout, and modification of large-scale-integrated (LSI) metal-oxide semiconductor (MOS) arrays. System is structured around small computer which provides real-time support for graphics storage display unit with keyboard, slave display unit, hard copy unit, and graphics tablet for designer/computer interface.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cutler, Dylan; Frank, Stephen; Slovensky, Michelle

Rich, well-organized building performance and energy consumption data enable a host of analytic capabilities for building owners and operators, from basic energy benchmarking to detailed fault detection and system optimization. Unfortunately, data integration for building control systems is challenging and costly in any setting. Large portfolios of buildings--campuses, cities, and corporate portfolios--experience these integration challenges most acutely. These large portfolios often have a wide array of control systems, including multiple vendors and nonstandard communication protocols. They typically have complex information technology (IT) networks and cybersecurity requirements and may integrate distributed energy resources into their infrastructure. Although the challenges are significant,more » the integration of control system data has the potential to provide proportionally greater value for these organizations through portfolio-scale analytics, comprehensive demand management, and asset performance visibility. As a large research campus, the National Renewable Energy Laboratory (NREL) experiences significant data integration challenges. To meet them, NREL has developed an architecture for effective data collection, integration, and analysis, providing a comprehensive view of data integration based on functional layers. The architecture is being evaluated on the NREL campus through deployment of three pilot implementations.« less

Multi-scale Modeling and Analysis of Nano-RFID Systems on HPC Setup

NASA Astrophysics Data System (ADS)

Pathak, Rohit; Joshi, Satyadhar

In this paper we have worked out on some the complex modeling aspects such as Multi Scale modeling, MATLAB Sugar based modeling and have shown the complexities involved in the analysis of Nano RFID (Radio Frequency Identification) systems. We have shown the modeling and simulation and demonstrated some novel ideas and library development for Nano RFID. Multi scale modeling plays a very important role in nanotech enabled devices properties of which cannot be explained sometimes by abstraction level theories. Reliability and packaging still remains one the major hindrances in practical implementation of Nano RFID based devices. And to work on them modeling and simulation will play a very important role. CNTs is the future low power material that will replace CMOS and its integration with CMOS, MEMS circuitry will play an important role in realizing the true power in Nano RFID systems. RFID based on innovations in nanotechnology has been shown. MEMS modeling of Antenna, sensors and its integration in the circuitry has been shown. Thus incorporating this we can design a Nano-RFID which can be used in areas like human implantation and complex banking applications. We have proposed modeling of RFID using the concept of multi scale modeling to accurately predict its properties. Also we give the modeling of MEMS devices that are proposed recently that can see possible application in RFID. We have also covered the applications and the advantages of Nano RFID in various areas. RF MEMS has been matured and its devices are being successfully commercialized but taking it to limits of nano domains and integration with singly chip RFID needs a novel approach which is being proposed. We have modeled MEMS based transponder and shown the distribution for multi scale modeling for Nano RFID.

Integrated bioprocess for conversion of gaseous substrates to liquids

PubMed Central

Hu, Peng; Chakraborty, Sagar; Kumar, Amit; Woolston, Benjamin; Liu, Hongjuan; Emerson, David; Stephanopoulos, Gregory

2016-01-01

In the quest for inexpensive feedstocks for the cost-effective production of liquid fuels, we have examined gaseous substrates that could be made available at low cost and sufficiently large scale for industrial fuel production. Here we introduce a new bioconversion scheme that effectively converts syngas, generated from gasification of coal, natural gas, or biomass, into lipids that can be used for biodiesel production. We present an integrated conversion method comprising a two-stage system. In the first stage, an anaerobic bioreactor converts mixtures of gases of CO2 and CO or H2 to acetic acid, using the anaerobic acetogen Moorella thermoacetica. The acetic acid product is fed as a substrate to a second bioreactor, where it is converted aerobically into lipids by an engineered oleaginous yeast, Yarrowia lipolytica. We first describe the process carried out in each reactor and then present an integrated system that produces microbial oil, using synthesis gas as input. The integrated continuous bench-scale reactor system produced 18 g/L of C16-C18 triacylglycerides directly from synthesis gas, with an overall productivity of 0.19 g⋅L−1⋅h−1 and a lipid content of 36%. Although suboptimal relative to the performance of the individual reactor components, the presented integrated system demonstrates the feasibility of substantial net fixation of carbon dioxide and conversion of gaseous feedstocks to lipids for biodiesel production. The system can be further optimized to approach the performance of its individual units so that it can be used for the economical conversion of waste gases from steel mills to valuable liquid fuels for transportation. PMID:26951649

An Integrated Assessment of Location-Dependent Scaling for Microalgae Biofuel Production Facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coleman, Andre M.; Abodeely, Jared; Skaggs, Richard

Successful development of a large-scale microalgae-based biofuels industry requires comprehensive analysis and understanding of the feedstock supply chain—from facility siting/design through processing/upgrading of the feedstock to a fuel product. The evolution from pilot-scale production facilities to energy-scale operations presents many multi-disciplinary challenges, including a sustainable supply of water and nutrients, operational and infrastructure logistics, and economic competitiveness with petroleum-based fuels. These challenges are addressed in part by applying the Integrated Assessment Framework (IAF)—an integrated multi-scale modeling, analysis, and data management suite—to address key issues in developing and operating an open-pond facility by analyzing how variability and uncertainty in space andmore » time affect algal feedstock production rates, and determining the site-specific “optimum” facility scale to minimize capital and operational expenses. This approach explicitly and systematically assesses the interdependence of biofuel production potential, associated resource requirements, and production system design trade-offs. The IAF was applied to a set of sites previously identified as having the potential to cumulatively produce 5 billion-gallons/year in the southeastern U.S. and results indicate costs can be reduced by selecting the most effective processing technology pathway and scaling downstream processing capabilities to fit site-specific growing conditions, available resources, and algal strains.« less

At the Nexus of History, Ecology, and Hydrobiogeochemistry: Improved Predictions across Scales through Integration

DOE PAGES

Stegen, James C.

2018-04-10

To improve predictions of ecosystem function in future environments, we need to integrate the ecological and environmental histories experienced by microbial communities with hydrobiogeochemistry across scales. A key issue is whether we can derive generalizable scaling relationships that describe this multiscale integration. There is a strong foundation for addressing these challenges. We have the ability to infer ecological history with null models and reveal impacts of environmental history through laboratory and field experimentation. Recent developments also provide opportunities to inform ecosystem models with targeted omics data. A major next step is coupling knowledge derived from such studies with multiscale modelingmore » frameworks that are predictive under non-steady-state conditions. This is particularly true for systems spanning dynamic interfaces, which are often hot spots of hydrobiogeochemical function. Here, we can advance predictive capabilities through a holistic perspective focused on the nexus of history, ecology, and hydrobiogeochemistry.« less

At the Nexus of History, Ecology, and Hydrobiogeochemistry: Improved Predictions across Scales through Integration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stegen, James C.

To improve predictions of ecosystem function in future environments, we need to integrate the ecological and environmental histories experienced by microbial communities with hydrobiogeochemistry across scales. A key issue is whether we can derive generalizable scaling relationships that describe this multiscale integration. There is a strong foundation for addressing these challenges. We have the ability to infer ecological history with null models and reveal impacts of environmental history through laboratory and field experimentation. Recent developments also provide opportunities to inform ecosystem models with targeted omics data. A major next step is coupling knowledge derived from such studies with multiscale modelingmore » frameworks that are predictive under non-steady-state conditions. This is particularly true for systems spanning dynamic interfaces, which are often hot spots of hydrobiogeochemical function. Here, we can advance predictive capabilities through a holistic perspective focused on the nexus of history, ecology, and hydrobiogeochemistry.« less

At the Nexus of History, Ecology, and Hydrobiogeochemistry: Improved Predictions across Scales through Integration.

PubMed

Stegen, James C

2018-01-01

To improve predictions of ecosystem function in future environments, we need to integrate the ecological and environmental histories experienced by microbial communities with hydrobiogeochemistry across scales. A key issue is whether we can derive generalizable scaling relationships that describe this multiscale integration. There is a strong foundation for addressing these challenges. We have the ability to infer ecological history with null models and reveal impacts of environmental history through laboratory and field experimentation. Recent developments also provide opportunities to inform ecosystem models with targeted omics data. A major next step is coupling knowledge derived from such studies with multiscale modeling frameworks that are predictive under non-steady-state conditions. This is particularly true for systems spanning dynamic interfaces, which are often hot spots of hydrobiogeochemical function. We can advance predictive capabilities through a holistic perspective focused on the nexus of history, ecology, and hydrobiogeochemistry.

Note on the ideal frame formulation

NASA Astrophysics Data System (ADS)

Lara, Martin

2017-09-01

An implementation of the ideal frame formulation of perturbed Keplerian motion is presented which only requires the integration of a differential system of dimension 7, contrary to the 8 variables traditionally integrated with this approach. The new formulation is based on the integration of a scaled version of the Eulerian set of redundant parameters and slightly improves runtime performance with respect to the 8-dimensional case while retaining comparable accuracy.

A Integrated Service Platform for Remote Sensing Image 3D Interpretation and Draughting based on HTML5

NASA Astrophysics Data System (ADS)

LIU, Yiping; XU, Qing; ZhANG, Heng; LV, Liang; LU, Wanjie; WANG, Dandi

2016-11-01

The purpose of this paper is to solve the problems of the traditional single system for interpretation and draughting such as inconsistent standards, single function, dependence on plug-ins, closed system and low integration level. On the basis of the comprehensive analysis of the target elements composition, map representation and similar system features, a 3D interpretation and draughting integrated service platform for multi-source, multi-scale and multi-resolution geospatial objects is established based on HTML5 and WebGL, which not only integrates object recognition, access, retrieval, three-dimensional display and test evaluation but also achieves collection, transfer, storage, refreshing and maintenance of data about Geospatial Objects and shows value in certain prospects and potential for growth.

A Navy Shore Activity Manpower Planning System for Civilians. Technical Report No. 24.

ERIC Educational Resources Information Center

Niehaus, R. J.; Sholtz, D.

This report describes the U.S. Navy Shore Activity Manpower Planning System (SAMPS) advanced development research project. This effort is aimed at large-scale feasibility tests of manpower models for large Naval installations. These local planning systems are integrated with Navy-wide information systems on a data-communications network accessible…

Advanced Hybrid Propulsion and Energy Management System for High Efficiency, Off Highway, 240 Ton Class, Diesel Electric Haul Trucks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richter, Tim; Slezak, Lee; Johnson, Chris

2008-12-31

The objective of this project is to reduce the fuel consumption of off-highway vehicles, specifically large tonnage mine haul trucks. A hybrid energy storage and management system will be added to a conventional diesel-electric truck that will allow capture of braking energy normally dissipated in grid resistors as heat. The captured energy will be used during acceleration and motoring, reducing the diesel engine load, thus conserving fuel. The project will work towards a system validation of the hybrid system by first selecting an energy storage subsystem and energy management subsystem. Laboratory testing at a subscale level will evaluate these selectionsmore » and then a full-scale laboratory test will be performed. After the subsystems have been proven at the full-scale lab, equipment will be mounted on a mine haul truck and integrated with the vehicle systems. The integrated hybrid components will be exercised to show functionality, capability, and fuel economy impacts in a mine setting.« less

A unifying framework for systems modeling, control systems design, and system operation

NASA Technical Reports Server (NTRS)

Dvorak, Daniel L.; Indictor, Mark B.; Ingham, Michel D.; Rasmussen, Robert D.; Stringfellow, Margaret V.

2005-01-01

Current engineering practice in the analysis and design of large-scale multi-disciplinary control systems is typified by some form of decomposition- whether functional or physical or discipline-based-that enables multiple teams to work in parallel and in relative isolation. Too often, the resulting system after integration is an awkward marriage of different control and data mechanisms with poor end-to-end accountability. System of systems engineering, which faces this problem on a large scale, cries out for a unifying framework to guide analysis, design, and operation. This paper describes such a framework based on a state-, model-, and goal-based architecture for semi-autonomous control systems that guides analysis and modeling, shapes control system software design, and directly specifies operational intent. This paper illustrates the key concepts in the context of a large-scale, concurrent, globally distributed system of systems: NASA's proposed Array-based Deep Space Network.

Integration of genomic and medical data into a 3D atlas of human anatomy.

PubMed

Turinsky, Andrei L; Fanea, Elena; Trinh, Quang; Dong, Xiaoli; Stromer, Julie N; Shu, Xueling; Wat, Stephen; Hallgrímsson, Benedikt; Hill, Jonathan W; Edwards, Carol; Grosenick, Brenda; Yajima, Masumi; Sensen, Christoph W

2008-01-01

We have developed a framework for the visual integration and exploration of multi-scale biomedical data, which includes anatomical and molecular components. We have also created a Java-based software system that integrates molecular information, such as gene expression data, into a three-dimensional digital atlas of the male adult human anatomy. Our atlas is structured according to the Terminologia Anatomica. The underlying data-indexing mechanism uses open standards and semantic ontology-processing tools to establish the associations between heterogeneous data types. The software system makes an extensive use of virtual reality visualization.

Enhanced Monocular Visual Odometry Integrated with Laser Distance Meter for Astronaut Navigation

PubMed Central

Wu, Kai; Di, Kaichang; Sun, Xun; Wan, Wenhui; Liu, Zhaoqin

2014-01-01

Visual odometry provides astronauts with accurate knowledge of their position and orientation. Wearable astronaut navigation systems should be simple and compact. Therefore, monocular vision methods are preferred over stereo vision systems, commonly used in mobile robots. However, the projective nature of monocular visual odometry causes a scale ambiguity problem. In this paper, we focus on the integration of a monocular camera with a laser distance meter to solve this problem. The most remarkable advantage of the system is its ability to recover a global trajectory for monocular image sequences by incorporating direct distance measurements. First, we propose a robust and easy-to-use extrinsic calibration method between camera and laser distance meter. Second, we present a navigation scheme that fuses distance measurements with monocular sequences to correct the scale drift. In particular, we explain in detail how to match the projection of the invisible laser pointer on other frames. Our proposed integration architecture is examined using a live dataset collected in a simulated lunar surface environment. The experimental results demonstrate the feasibility and effectiveness of the proposed method. PMID:24618780

Virtual Tissues and Developmental Systems Biology (book chapter)

EPA Science Inventory

Virtual tissue (VT) models provide an in silico environment to simulate cross-scale properties in specific tissues or organs based on knowledge of the underlying biological networks. These integrative models capture the fundamental interactions in a biological system and enable ...

A Watershed-scale Design Optimization Model for Stormwater Best Management Practices

EPA Science Inventory

U.S. Environmental Protection Agency developed a decision-support system, System for Urban Stormwater Treatment and Analysis Integration (SUSTAIN), to evaluate alternative plans for stormwater quality management and flow abatement techniques in urban and developing areas. SUSTAI...

ROADNET: A Real-time Data Aware System for Earth, Oceanographic, and Environmental Applications

NASA Astrophysics Data System (ADS)

Vernon, F.; Hansen, T.; Lindquist, K.; Ludascher, B.; Orcutt, J.; Rajasekar, A.

2003-12-01

The Real-time Observatories, Application, and Data management Network (ROADNet) Program aims to develop an integrated, seamless, and transparent environmental information network that will deliver geophysical, oceanographic, hydrological, ecological, and physical data to a variety of users in real-time. ROADNet is a multidisciplinary, multinational partnership of researchers, policymakers, natural resource managers, educators, and students who aim to use the data to advance our understanding and management of coastal, ocean, riparian, and terrestrial Earth systems in Southern California, Mexico, and well off shore. To date, project activity and funding have focused on the design and deployment of network linkages and on the exploratory development of the real-time data management system. We are currently adapting powerful "Data Grid" technologies to the unique challenges associated with the management and manipulation of real-time data. Current "Grid" projects deal with static data files, and significant technical innovation is required to address fundamental problems of real-time data processing, integration, and distribution. The technologies developed through this research will create a system that dynamically adapt downstream processing, cataloging, and data access interfaces when sensors are added or removed from the system; provide for real-time processing and monitoring of data streams--detecting events, and triggering computations, sensor and logger modifications, and other actions; integrate heterogeneous data from multiple (signal) domains; and provide for large-scale archival and querying of "consolidated" data. The software tools which must be developed do not exist, although limited prototype systems are available. This research has implications for the success of large-scale NSF initiatives in the Earth sciences (EarthScope), ocean sciences (OOI- Ocean Observatories Initiative), biological sciences (NEON - National Ecological Observatory Network) and civil engineering (NEES - Network for Earthquake Engineering Simulation). Each of these large scale initiatives aims to collect real-time data from thousands of sensors, and each will require new technologies to process, manage, and communicate real-time multidisciplinary environmental data on regional, national, and global scales.

Three-dimensional integrated circuits for lab-on-chip dielectrophoresis of nanometer scale particles

NASA Astrophysics Data System (ADS)

Dickerson, Samuel J.; Noyola, Arnaldo J.; Levitan, Steven P.; Chiarulli, Donald M.

2007-01-01

In this paper, we present a mixed-technology micro-system for electronically manipulating and optically detecting virusscale particles in fluids that is designed using 3D integrated circuit technology. During the 3D fabrication process, the top-most chip tier is assembled upside down and the substrate material is removed. This places the polysilicon layer, which is used to create geometries with the process' minimum feature size, in close proximity to a fluid channel etched into the top of the stack. By taking advantage of these processing features inherent to "3D chip-stacking" technology, we create electrode arrays that have a gap spacing of 270 nm. Using 3D CMOS technology also provides the ability to densely integrate analog and digital control circuitry for the electrodes by using the additional levels of the chip stack. We show simulations of the system with a physical model of a Kaposi's sarcoma-associated herpes virus, which has a radius of approximately 125 nm, being dielectrophoretically arranged into striped patterns. We also discuss how these striped patterns of trapped nanometer scale particles create an effective diffraction grating which can then be sensed with macro-scale optical techniques.

Avoiding Implementation Failure in Catchment Landscapes: A Case Study in Governance of the Great Barrier Reef.

PubMed

Dale, Allan P; Vella, Karen; Gooch, Margaret; Potts, Ruth; Pressey, Robert L; Brodie, Jon; Eberhard, Rachel

2017-10-04

Water quality outcomes affecting Australia's Great Barrier Reef (GBR) are governed by multi-level and multi-party decision-making that influences forested and agricultural landscapes. With international concern about the GBR's declining ecological health, this paper identifies and focuses on implementation failure (primarily at catchment scale) as a systemic risk within the overall GBR governance system. There has been limited integrated analysis of the full suite of governance subdomains that often envelop defined policies, programs and delivery activities that influence water quality in the GBR. We consider how the implementation of separate purpose-specific policies and programs at catchment scale operate against well-known, robust design concepts for integrated catchment governance. We find design concerns within ten important governance subdomains that operate within GBR catchments. At a whole-of-GBR scale, we find a weak policy focus on strengthening these delivery-oriented subdomains and on effort integration across these subdomains within catchments. These governance problems when combined may contribute to failure in the implementation of major national, state and local government policies focused on improving water quality in the GBR, a lesson relevant to landscapes globally.

Maintaining a Local Data Integration System in Support of Weather Forecast Operations

NASA Technical Reports Server (NTRS)

Watson, Leela R.; Blottman, Peter F.; Sharp, David W.; Hoeth, Brian

2010-01-01

Since 2000, both the National Weather Service in Melbourne, FL (NWS MLB) and the Spaceflight Meteorology Group (SMG) at Johnson Space Center in Houston, TX have used a local data integration system (LDIS) as part of their forecast and warning operations. The original LDIS was developed by NASA's Applied Meteorology Unit (AMU; Bauman et ai, 2004) in 1998 (Manobianco and Case 1998) and has undergone subsequent improvements. Each has benefited from three-dimensional (3-D) analyses that are delivered to forecasters every 15 minutes across the peninsula of Florida. The intent is to generate products that enhance short-range weather forecasts issued in support of NWS MLB and SMG operational requirements within East Central Florida. The current LDIS uses the Advanced Regional Prediction System (ARPS) Data Analysis System (ADAS) package as its core, which integrates a wide variety of national, regional, and local observational data sets. It assimilates all available real-time data within its domain and is run at a finer spatial and temporal resolution than current national- or regional-scale analysis packages. As such, it provides local forecasters with a more comprehensive understanding of evolving fine-scale weather features

Visualization and Interactivity in the Teaching of Chemistry to Science and Non-Science Students

ERIC Educational Resources Information Center

Venkataraman, Bhawani

2009-01-01

A series of interactive, instructional units have been developed that integrate computational molecular modelling and visualization to teach fundamental chemistry concepts and the relationship between the molecular and macro-scales. The units span the scale from atoms, small molecules to macromolecular systems, and introduce many of the concepts…

Introducing Subgrid-scale convective cloud and aerosol interactions to the WRF-CMAQ integrated modeling system

EPA Science Inventory

Many regional and global climate models include aerosol indirect effects (AIE) on grid-scale/resolved clouds. However, the interaction between aerosols and convective clouds remains highly uncertain, as noted in the IPCC AR4 report. The objective of this work is to help fill in ...

Implantable neurotechnologies: bidirectional neural interfaces--applications and VLSI circuit implementations.

PubMed

Greenwald, Elliot; Masters, Matthew R; Thakor, Nitish V

2016-01-01

A bidirectional neural interface is a device that transfers information into and out of the nervous system. This class of devices has potential to improve treatment and therapy in several patient populations. Progress in very large-scale integration has advanced the design of complex integrated circuits. System-on-chip devices are capable of recording neural electrical activity and altering natural activity with electrical stimulation. Often, these devices include wireless powering and telemetry functions. This review presents the state of the art of bidirectional circuits as applied to neuroprosthetic, neurorepair, and neurotherapeutic systems.

Bidirectional Neural Interfaces

PubMed Central

Masters, Matthew R.; Thakor, Nitish V.

2016-01-01

A bidirectional neural interface is a device that transfers information into and out of the nervous system. This class of devices has potential to improve treatment and therapy in several patient populations. Progress in very-large-scale integration (VLSI) has advanced the design of complex integrated circuits. System-on-chip (SoC) devices are capable of recording neural electrical activity and altering natural activity with electrical stimulation. Often, these devices include wireless powering and telemetry functions. This review presents the state of the art of bidirectional circuits as applied to neuroprosthetic, neurorepair, and neurotherapeutic systems. PMID:26753776

Facilitating CCS Business Planning by Extending the Functionality of the SimCCS Integrated System Model

DOE PAGES

Ellett, Kevin M.; Middleton, Richard S.; Stauffer, Philip H.; ...

2017-08-18

The application of integrated system models for evaluating carbon capture and storage technology has expanded steadily over the past few years. To date, such models have focused largely on hypothetical scenarios of complex source-sink matching involving numerous large-scale CO 2 emitters, and high-volume, continuous reservoirs such as deep saline formations to function as geologic sinks for carbon storage. Though these models have provided unique insight on the potential costs and feasibility of deploying complex networks of integrated infrastructure, there remains a pressing need to translate such insight to the business community if this technology is to ever achieve a trulymore » meaningful impact in greenhouse gas mitigation. Here, we present a new integrated system modelling tool termed SimCCUS aimed at providing crucial decision support for businesses by extending the functionality of a previously developed model called SimCCS. The primary innovation of the SimCCUS tool development is the incorporation of stacked geological reservoir systems with explicit consideration of processes and costs associated with the operation of multiple CO 2 utilization and storage targets from a single geographic location. In such locations provide significant efficiencies through economies of scale, effectively minimizing CO 2 storage costs while simultaneously maximizing revenue streams via the utilization of CO 2 as a commodity for enhanced hydrocarbon recovery.« less

Facilitating CCS Business Planning by Extending the Functionality of the SimCCS Integrated System Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ellett, Kevin M.; Middleton, Richard S.; Stauffer, Philip H.

The application of integrated system models for evaluating carbon capture and storage technology has expanded steadily over the past few years. To date, such models have focused largely on hypothetical scenarios of complex source-sink matching involving numerous large-scale CO 2 emitters, and high-volume, continuous reservoirs such as deep saline formations to function as geologic sinks for carbon storage. Though these models have provided unique insight on the potential costs and feasibility of deploying complex networks of integrated infrastructure, there remains a pressing need to translate such insight to the business community if this technology is to ever achieve a trulymore » meaningful impact in greenhouse gas mitigation. Here, we present a new integrated system modelling tool termed SimCCUS aimed at providing crucial decision support for businesses by extending the functionality of a previously developed model called SimCCS. The primary innovation of the SimCCUS tool development is the incorporation of stacked geological reservoir systems with explicit consideration of processes and costs associated with the operation of multiple CO 2 utilization and storage targets from a single geographic location. In such locations provide significant efficiencies through economies of scale, effectively minimizing CO 2 storage costs while simultaneously maximizing revenue streams via the utilization of CO 2 as a commodity for enhanced hydrocarbon recovery.« less

Biomass District Heat System for Interior Rural Alaska Villages

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wall, William A.; Parker, Charles R.

2014-09-01

Alaska Village Initiatives (AVI) from the outset of the project had a goal of developing an integrated village approach to biomass in Rural Alaskan villages. A successful biomass project had to be ecologically, socially/culturally and economically viable and sustainable. Although many agencies were supportive of biomass programs in villages none had the capacity to deal effectively with developing all of the tools necessary to build a complete integrated program. AVI had a sharp learning curve as well. By the end of the project with all the completed tasks, AVI developed the tools and understanding to connect all of the dotsmore » of an integrated village based program. These included initially developing a feasibility model that created the capacity to optimize a biomass system in a village. AVI intent was to develop all aspects or components of a fully integrated biomass program for a village. This meant understand the forest resource and developing a sustainable harvest system that included the “right sized” harvest equipment for the scale of the project. Developing a training program for harvesting and managing the forest for regeneration. Making sure the type, quality, and delivery system matched the needs of the type of boiler or boilers to be installed. AVI intended for each biomass program to be of the scale that would create jobs and a sustainable business.« less

Aerodynamic Design of a Dual-Flow Mach 7 Hypersonic Inlet System for a Turbine-Based Combined-Cycle Hypersonic Propulsion System

NASA Technical Reports Server (NTRS)

Sanders, Bobby W.; Weir, Lois J.

2008-01-01

A new hypersonic inlet for a turbine-based combined-cycle (TBCC) engine has been designed. This split-flow inlet is designed to provide flow to an over-under propulsion system with turbofan and dual-mode scramjet engines for flight from takeoff to Mach 7. It utilizes a variable-geometry ramp, high-speed cowl lip rotation, and a rotating low-speed cowl that serves as a splitter to divide the flow between the low-speed turbofan and the high-speed scramjet and to isolate the turbofan at high Mach numbers. The low-speed inlet was designed for Mach 4, the maximum mode transition Mach number. Integration of the Mach 4 inlet into the Mach 7 inlet imposed significant constraints on the low-speed inlet design, including a large amount of internal compression. The inlet design was used to develop mechanical designs for two inlet mode transition test models: small-scale (IMX) and large-scale (LIMX) research models. The large-scale model is designed to facilitate multi-phase testing including inlet mode transition and inlet performance assessment, controls development, and integrated systems testing with turbofan and scramjet engines.

An innovative integrated oxidation ditch with vertical circle (IODVC) for wastewater treatment.

PubMed

Xia, Shi-bin; Liu, Jun-xin

2004-01-01

The oxidation ditch process is economic and efficient for wastewater treatment, but its application is limited in case where land is costly due to its large land area required. An innovative integrated oxidation ditch with vertical circle (IODVC) system was developed to treat domestic and industrial wastewater aiming to save land area. The new system consists of a single-channel divided into two ditches(the top one and the bottom one by a plate), a brush, and an innovative integral clarifier. Different from the horizontal circle of the conventional oxidation ditch, the flow of IODVC system recycles from the top zone to the bottom zone in the vertical circle as the brush is running, and then the IODVC saved land area required by about 50% compared with a conventional oxidation ditch with an intrachannel clarifier. The innovative integral clarifier is effective for separation of liquid and solids, and is preferably positioned at the opposite end of the brush in the ditch. It does not affect the hydrodynamic characteristics of the mixed liquor in the ditch, and the sludge can automatically return to the down ditch without any pump. In this study, experiments of domestic and dye wastewater treatment were carried out in bench scale and in full scale, respectively. Results clearly showed that the IODVC efficiently removed pollutants in the wastewaters, i.e., the average of COD removals for domestic and dye wastewater treatment were 95% and 90%, respectively, and that the IODVC process may provide a cost effective way for full scale dye wastewater treatment.

Water, ecology and health: ecosystems as settings for promoting health and sustainability.

PubMed

Parkes, Margot W; Horwitz, Pierre

2009-03-01

Despite the proposed ecological and systems-based perspectives of the settings-based approach to health promotion, most initiatives have tended to overlook the fundamental nature of ecosystems. This paper responds to this oversight by proposing an explicit re-integration of ecosystems within the healthy settings approach. We make this case by focusing on water as an integrating unit of analysis. Water, on which all life depends, is not only an integral consideration for the existing healthy settings (schools, hospitals, workplaces) but also highlights the ecosystem context of health and sustainability. A focus on catchments (also know as watersheds and river basins) exemplifies the scaled and upstream/downstream nature of ecosystems and draws into sharp focus the cross-sectoral and transdisciplinary context of the social and environmental determinants of health. We position this work in relation to the converging agendas of health promotion and ecosystem management at the local, regional and global scales--and draw on evidence from international initiatives as diverse as the WHO Commission on Social Determinants of Health, and the Millennium Ecosystem Assessment. Using water as a vehicle for understanding the systemic context for human wellbeing, health promotion and disease prevention draws inevitable attention to key challenges of scale, intersectoral governance and the complementary themes of promoting resilience and preventing vulnerability. We conclude by highlighting the importance of building individual and institutional capacity for this kind of integration--equipping a new generation of researchers, practitioners and decision-makers to be conversant with the language of ecosystems, capable of systemic thought and focused on settings that can promote both health and sustainability.

IGMS: An Integrated ISO-to-Appliance Scale Grid Modeling System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Palmintier, Bryan; Hale, Elaine; Hansen, Timothy M.

This paper describes the Integrated Grid Modeling System (IGMS), a novel electric power system modeling platform for integrated transmission-distribution analysis that co-simulates off-the-shelf tools on high performance computing (HPC) platforms to offer unprecedented resolution from ISO markets down to appliances and other end uses. Specifically, the system simultaneously models hundreds or thousands of distribution systems in co-simulation with detailed Independent System Operator (ISO) markets and AGC-level reserve deployment. IGMS uses a new MPI-based hierarchical co-simulation framework to connect existing sub-domain models. Our initial efforts integrate opensource tools for wholesale markets (FESTIV), bulk AC power flow (MATPOWER), and full-featured distribution systemsmore » including physics-based end-use and distributed generation models (many instances of GridLAB-D[TM]). The modular IGMS framework enables tool substitution and additions for multi-domain analyses. This paper describes the IGMS tool, characterizes its performance, and demonstrates the impacts of the coupled simulations for analyzing high-penetration solar PV and price responsive load scenarios.« less

Excess sludge reduction using pilot-scale lysis-cryptic growth system integrated ultrasonic/alkaline disintegration and hydrolysis/acidogenesis pretreatment.

PubMed

Ma, Huaji; Zhang, Shuting; Lu, Xuebin; Xi, Bo; Guo, Xingli; Wang, Han; Duan, Jingxiao

2012-07-01

A pilot-scale lysis-cryptic growth system was built and operated continuously for excess sludge reduction. Combined ultrasonic/alkaline disintegration and hydrolysis/acidogenesis were integrated into its sludge pretreatment system. Continuous operation showed that the observed biomass yield and the sludge reduction efficiency of the lysis-cryptic growth system were 0.27 kg VSS/kg COD consumed and 56.5%, respectively. The water quality of its effluent was satisfactory. The sludge pretreatment system performed well and its TCOD removal efficiency was 7.9% which contributed a sludge reduction efficiency of 2.1%. The SCOD, VFA, TN, NH(4)(+)-N, TP and pH in the supernatant of pretreated sludge were 1790 mg/L, 1530 mg COD/L, 261.1mg/L, 114.0mg/L, 93.1mg/L and 8.69, respectively. The total operation cost of the lysis-cryptic growth system was $ 0.186/m(3) wastewater, which was 11.4% less than that of conventional activated sludge (CAS) system without excess sludge pretreatment. Copyright © 2012 Elsevier Ltd. All rights reserved.

Integrative monitoring of water storage variations at the landscape-scale with an iGrav superconducting gravimeter in a field enclosure

NASA Astrophysics Data System (ADS)

Guntner, A.; Reich, M.; Mikolaj, M.; Creutzfeldt, B.; Schroeder, S.; Wziontek, H.

2017-12-01

In spite of the fundamental role of the landscape water balance for the Earth's water and energy cycles, monitoring the water balance and related storage dynamics beyond the point scale is notoriously difficult due to the multitude of flow and storage processes and their spatial heterogeneity. We present the first outdoor deployment of an iGrav superconducting gravimeter (SG) in a minimized field enclosure on a wet-temperate grassland site for integrative monitoring of water storage changes. It is shown that the system performs similarly precise as SGs that have hitherto been deployed in observatory buildings, but with higher sensitivity to hydrological variations in the surroundings of the instrument. Gravity variations observed by the field setup are almost independent of the depth below the terrain surface where water storage changes occur, and thus the field SG system directly observes the total water storage change in an integrative way. We provide a framework to single out the water balance components actual evapotranspiration and lateral subsurface discharge from the gravity time series on annual to daily time scales. With about 99% and 85% of the gravity signal originating within a radius of 4000 and 200 meter around the instrument, respectively, the setup paves the road towards gravimetry as a continuous hydrological field monitoring technique for water storage dynamics at the landscape scale.

System-Scale Model of Aquifer, Vadose Zone, and River Interactions for the Hanford 300 Area - Application to Uranium Reactive Transport

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rockhold, Mark L.; Bacon, Diana H.; Freedman, Vicky L.

2013-10-01

This report represents a synthesis and integration of basic and applied research into a system-scale model of the Hanford 300 Area groundwater uranium plume, supported by the U.S. Department of Energy’s Richland Operations (DOE-RL) office. The report integrates research findings and data from DOE Office of Science (DOE-SC), Office of Environmental Management (DOE-EM), and DOE-RL projects, and from the site remediation and closure contractor, Washington Closure Hanford, LLC (WCH). The three-dimensional, system-scale model addresses water flow and reactive transport of uranium for the coupled vadose zone, unconfined aquifer, and Columbia River shoreline of the Hanford 300 Area. The system-scale modelmore » of the 300 Area was developed to be a decision-support tool to evaluate processes of the total system affecting the groundwater uranium plume. The model can also be used to address “what if” questions regarding different remediation endpoints, and to assist in design and evaluation of field remediation efforts. For example, the proposed cleanup plan for the Hanford 300 Area includes removal, treatment, and disposal of contaminated sediments from known waste sites, enhanced attenuation of uranium hot spots in the vadose and periodically rewetted zone, and continued monitoring of groundwater with institutional controls. Illustrative simulations of polyphosphate infiltration were performed to demonstrate the ability of the system-scale model to address these types of questions. The use of this model in conjunction with continued field monitoring is expected to provide a rigorous basis for developing operational strategies for field remediation and for defining defensible remediation endpoints.« less

Evolving from bioinformatics in-the-small to bioinformatics in-the-large.

PubMed

Parker, D Stott; Gorlick, Michael M; Lee, Christopher J

2003-01-01

We argue the significance of a fundamental shift in bioinformatics, from in-the-small to in-the-large. Adopting a large-scale perspective is a way to manage the problems endemic to the world of the small-constellations of incompatible tools for which the effort required to assemble an integrated system exceeds the perceived benefit of the integration. Where bioinformatics in-the-small is about data and tools, bioinformatics in-the-large is about metadata and dependencies. Dependencies represent the complexities of large-scale integration, including the requirements and assumptions governing the composition of tools. The popular make utility is a very effective system for defining and maintaining simple dependencies, and it offers a number of insights about the essence of bioinformatics in-the-large. Keeping an in-the-large perspective has been very useful to us in large bioinformatics projects. We give two fairly different examples, and extract lessons from them showing how it has helped. These examples both suggest the benefit of explicitly defining and managing knowledge flows and knowledge maps (which represent metadata regarding types, flows, and dependencies), and also suggest approaches for developing bioinformatics database systems. Generally, we argue that large-scale engineering principles can be successfully adapted from disciplines such as software engineering and data management, and that having an in-the-large perspective will be a key advantage in the next phase of bioinformatics development.

Integrated Modeling of Aerosol, Cloud, Precipitation and Land Processes at Satellite-Resolved Scales

NASA Technical Reports Server (NTRS)

Peters-Lidard, Christa; Tao, Wei-Kuo; Chin, Mian; Braun, Scott; Case, Jonathan; Hou, Arthur; Kumar, Anil; Kumar, Sujay; Lau, William; Matsui, Toshihisa;

An Evaluation of Operational Airspace Sectorization Integrated System (OASIS) Advisory Tool

NASA Technical Reports Server (NTRS)

Lee, Paul U.; Mogford, Richard H.; Bridges, Wayne; Buckley, Nathan; Evans, Mark; Gujral, Vimmy; Lee, Hwasoo; Peknik, Daniel; Preston, William

2013-01-01

In January 2013, a human-in-the-loop evaluation of the Operational Airspace Sectorization Integrated System (OASIS) was conducted in the Airspace Operations Laboratory of the Human Systems Integration Division (Code TH) in conjunction with the Aviation Systems Division (Code AF). The development of OASIS is a major activity of the Dynamic Airspace Configuration (DAC) research focus area within the Aeronautics Research Mission Directorate (ARMD) Airspace Systems Program. OASIS is an advisory tool to assist Federal Aviation Administration (FAA) En Route Area Supervisors in their planning of sector combinedecombine operations as well as opening closing of Data-side (D-side) control positions. These advisory solutions are tailored to the predicted traffic demand over the next few hours. During the experiment, eight retired FAA personnel served as participants for a part-task evaluation of OASIS functionality, covering the user interface as well as the underlying algorithm. Participants gave positive feedback on both the user interface and the algorithm solutions for airspace configuration, including an excellent average rating of 94 on the tool usability scales. They also suggested various enhancements to the OASIS tool, which will be incorporated into the next tool development cycle for the full-scale human-in-the-loop evaluation to be conducted later this year.

Path-integral Monte Carlo method for Rényi entanglement entropies.

PubMed

Herdman, C M; Inglis, Stephen; Roy, P-N; Melko, R G; Del Maestro, A

2014-07-01

We introduce a quantum Monte Carlo algorithm to measure the Rényi entanglement entropies in systems of interacting bosons in the continuum. This approach is based on a path-integral ground state method that can be applied to interacting itinerant bosons in any spatial dimension with direct relevance to experimental systems of quantum fluids. We demonstrate how it may be used to compute spatial mode entanglement, particle partitioned entanglement, and the entanglement of particles, providing insights into quantum correlations generated by fluctuations, indistinguishability, and interactions. We present proof-of-principle calculations and benchmark against an exactly soluble model of interacting bosons in one spatial dimension. As this algorithm retains the fundamental polynomial scaling of quantum Monte Carlo when applied to sign-problem-free models, future applications should allow for the study of entanglement entropy in large-scale many-body systems of interacting bosons.

Configurations and implementation of payroll system using open source erp: a case study of Koperasi PT Sri

NASA Astrophysics Data System (ADS)

Terminanto, A.; Swantoro, H. A.; Hidayanto, A. N.

2017-12-01

Enterprise Resource Planning (ERP) is an integrated information system to manage business processes of companies of various business scales. Because of the high cost of ERP investment, ERP implementation is usually done in large-scale enterprises, Due to the complexity of implementation problems, the success rate of ERP implementation is still low. Open Source System ERP becomes an alternative choice of ERP application to SME companies in terms of cost and customization. This study aims to identify characteristics and configure the implementation of OSS ERP Payroll module in KKPS (Employee Cooperative PT SRI) using OSS ERP Odoo and using ASAP method. This study is classified into case study research and action research. Implementation of OSS ERP Payroll module is done because the HR section of KKPS has not been integrated with other parts. The results of this study are the characteristics and configuration of OSS ERP payroll module in KKPS.

System design and integration of the large-scale advanced prop-fan

NASA Technical Reports Server (NTRS)

Huth, B. P.

1986-01-01

In recent years, considerable attention has been directed toward improving aircraft fuel consumption. Studies have shown that blades with thin airfoils and aerodynamic sweep extend the inherent efficiency advantage that turboprop propulsion systems have demonstrated to the higher speed to today's aircraft. Hamilton Standard has designed a 9-foot diameter single-rotation Prop-Fan. It will test the hardware on a static test stand, in low speed and high speed wind tunnels and on a research aircraft. The major objective of this testing is to establish the structural integrity of large scale Prop-Fans of advanced construction, in addition to the evaluation of aerodynamic performance and the aeroacoustic design. The coordination efforts performed to ensure smooth operation and assembly of the Prop-Fan are summarized. A summary of the loads used to size the system components, the methodology used to establish material allowables and a review of the key analytical results are given.

Thermodynamic Vent System for an On-Orbit Cryogenic Reaction Control Engine

NASA Technical Reports Server (NTRS)

Hurlbert, Eric A.; Romig, Kris A.; Jimenez, Rafael; Flores, Sam

2012-01-01

A report discusses a cryogenic reaction control system (RCS) that integrates a Joule-Thompson (JT) device (expansion valve) and thermodynamic vent system (TVS) with a cryogenic distribution system to allow fine control of the propellant quality (subcooled liquid) during operation of the device. It enables zero-venting when coupled with an RCS engine. The proper attachment locations and sizing of the orifice are required with the propellant distribution line to facilitate line conditioning. During operations, system instrumentation was strategically installed along the distribution/TVS line assembly, and temperature control bands were identified. A sub-scale run tank, full-scale distribution line, open-loop TVS, and a combination of procured and custom-fabricated cryogenic components were used in the cryogenic RCS build-up. Simulated on-orbit activation and thruster firing profiles were performed to quantify system heat gain and evaluate the TVS s capability to maintain the required propellant conditions at the inlet to the engine valves. Test data determined that a small control valve, such as a piezoelectric, is optimal to provide continuously the required thermal control. The data obtained from testing has also assisted with the development of fluid and thermal models of an RCS to refine integrated cryogenic propulsion system designs. This system allows a liquid oxygenbased main propulsion and reaction control system for a spacecraft, which improves performance, safety, and cost over conventional hypergolic systems due to higher performance, use of nontoxic propellants, potential for integration with life support and power subsystems, and compatibility with in-situ produced propellants.

SCALE Code System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rearden, Bradley T.; Jessee, Matthew Anderson

The SCALE Code System is a widely-used modeling and simulation suite for nuclear safety analysis and design that is developed, maintained, tested, and managed by the Reactor and Nuclear Systems Division (RNSD) of Oak Ridge National Laboratory (ORNL). SCALE provides a comprehensive, verified and validated, user-friendly tool set for criticality safety, reactor and lattice physics, radiation shielding, spent fuel and radioactive source term characterization, and sensitivity and uncertainty analysis. Since 1980, regulators, licensees, and research institutions around the world have used SCALE for safety analysis and design. SCALE provides an integrated framework with dozens of computational modules including three deterministicmore » and three Monte Carlo radiation transport solvers that are selected based on the desired solution strategy. SCALE includes current nuclear data libraries and problem-dependent processing tools for continuous-energy (CE) and multigroup (MG) neutronics and coupled neutron-gamma calculations, as well as activation, depletion, and decay calculations. SCALE includes unique capabilities for automated variance reduction for shielding calculations, as well as sensitivity and uncertainty analysis. SCALE’s graphical user interfaces assist with accurate system modeling, visualization of nuclear data, and convenient access to desired results.« less

SCALE Code System 6.2.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rearden, Bradley T.; Jessee, Matthew Anderson

The SCALE Code System is a widely-used modeling and simulation suite for nuclear safety analysis and design that is developed, maintained, tested, and managed by the Reactor and Nuclear Systems Division (RNSD) of Oak Ridge National Laboratory (ORNL). SCALE provides a comprehensive, verified and validated, user-friendly tool set for criticality safety, reactor and lattice physics, radiation shielding, spent fuel and radioactive source term characterization, and sensitivity and uncertainty analysis. Since 1980, regulators, licensees, and research institutions around the world have used SCALE for safety analysis and design. SCALE provides an integrated framework with dozens of computational modules including three deterministicmore » and three Monte Carlo radiation transport solvers that are selected based on the desired solution strategy. SCALE includes current nuclear data libraries and problem-dependent processing tools for continuous-energy (CE) and multigroup (MG) neutronics and coupled neutron-gamma calculations, as well as activation, depletion, and decay calculations. SCALE includes unique capabilities for automated variance reduction for shielding calculations, as well as sensitivity and uncertainty analysis. SCALE’s graphical user interfaces assist with accurate system modeling, visualization of nuclear data, and convenient access to desired results.« less

Deployment of ERP Systems at Automotive Industries, Security Inspection (Case Study: IRAN KHODRO Automotive Company)

NASA Astrophysics Data System (ADS)

Ali, Hatamirad; Hasan, Mehrjerdi

Automotive industry and car production process is one of the most complex and large-scale production processes. Today, information technology (IT) and ERP systems incorporates a large portion of production processes. Without any integrated systems such as ERP, the production and supply chain processes will be tangled. The ERP systems, that are last generation of MRP systems, make produce and sale processes of these industries easier and this is the major factor of development of these industries anyhow. Today many of large-scale companies are developing and deploying the ERP systems. The ERP systems facilitate many of organization processes and make organization to increase efficiency. The security is a very important part of the ERP strategy at the organization, Security at the ERP systems, because of integrity and extensive, is more important of local and legacy systems. Disregarding of this point can play a giant role at success or failure of this kind of systems. The IRANKHODRO is the biggest automotive factory in the Middle East with an annual production over 600.000 cars. This paper presents ERP security deployment experience at the "IRANKHODRO Company". Recently, by launching ERP systems, it moved a big step toward more developments.

Characteristic Time Scales of Characteristic Magmatic Processes and Systems

NASA Astrophysics Data System (ADS)

Marsh, B. D.

2004-05-01

Every specific magmatic process, regardless of spatial scale, has an associated characteristic time scale. Time scales associated with crystals alone are rates of growth, dissolution, settling, aggregation, annealing, and nucleation, among others. At the other extreme are the time scales associated with the dynamics of the entire magmatic system. These can be separated into two groups: those associated with system genetics (e.g., the production and transport of magma, establishment of the magmatic system) and those due to physical characteristics of the established system (e.g., wall rock failure, solidification front propagation and instability, porous flow). The detailed geometry of a specific magmatic system is particularly important to appreciate; although generic systems are useful, care must be taken to make model systems as absolutely realistic as possible. Fuzzy models produce fuzzy science. Knowledge of specific time scales is not necessarily useful or meaningful unless the hierarchical context of the time scales for a realistic magmatic system is appreciated. The age of a specific phenocryst or ensemble of phenocrysts, as determined from isotopic or CSD studies, is not meaningful unless something can be ascertained of the provenance of the crystals. For example, crystal size multiplied by growth rate gives a meaningful crystal age only if it is from a part of the system that has experienced semi-monotonic cooling prior to chilling; crystals entrained from a long-standing cumulate bed that were mechanically sorted in ascending magma may not reveal this history. Ragged old crystals rolling about in the system for untold numbers of flushing times record specious process times, telling more about the noise in the system than the life of typical, first generation crystallization processes. The most helpful process-related time scales are those that are known well and that bound or define the temporal style of the system. Perhaps the most valuable of these times comes from the observed durations and rates of volcanism. There can be little doubt that the temporal styles of volcanism are the same as those of magmatism in general. Volcano repose times, periodicity, eruptive fluxes, acoustic emission structures, lava volumes, longevity, etc. must also be characteristic of pluton-dominated systems. We must therefore give up some classical concepts (e.g., instantaneous injection of crystal-free magma as an initial condition) for any plutonic/chambered system and move towards an integrated concept of magmatism. Among the host of process-related time scales, probably the three most fundamental of any magmatic system are (1) the time scale associated with crystal nucleation (J) and growth (G) (tx}=C{1(G3 J)-{1}/4; Zieg & Marsh, J. Pet. 02') along with the associated scales for mean crystal size (L) and population (N), (2) the time scale associated with conductive cooling controlled by a local length scale (d) (tc}=C{2 d2/K; K is thermal diffusivity), and (3) the time scale associated with intra-crystal diffusion (td}=C{3 L2/D; D is chemical diffusivity). It is the subtle, clever, and insightful application of time scales, dovetailed with realistic system geometry and attention paid to the analogous time scales of volcanism, that promises to reveal the true dynamic integration of magmatic systems.

A fiber-optic ice detection system for large-scale wind turbine blades

NASA Astrophysics Data System (ADS)

Kim, Dae-gil; Sampath, Umesh; Kim, Hyunjin; Song, Minho

2017-09-01

Icing causes substantial problems in the integrity of large-scale wind turbines. In this work, a fiber-optic sensor system for detection of icing with an arrayed waveguide grating is presented. The sensor system detects Fresnel reflections from the ends of the fibers. The transition in Fresnel reflection due to icing gives peculiar intensity variations, which categorizes the ice, the water, and the air medium on the wind turbine blades. From the experimental results, with the proposed sensor system, the formation of icing conditions and thickness of ice were identified successfully in real time.

Spatial Distribution of Fate and Transport Parameters Using Cxtfit in a Karstified Limestone Model

NASA Astrophysics Data System (ADS)

Toro, J.; Padilla, I. Y.

2017-12-01

Karst environments have a high capacity to transport and store large amounts of water. This makes karst aquifers a productive resource for human consumption and ecological integrity, but also makes them vulnerable to potential contamination of hazardous chemical substances. High heterogeneity and anisotropy of karst aquifer properties make them very difficult to characterize for accurate prediction of contaminant mobility and persistence in groundwater. Current technologies to characterize and quantify flow and transport processes at field-scale is limited by low resolution of spatiotemporal data. To enhance this resolution and provide the essential knowledge of karst groundwater systems, studies at laboratory scale can be conducted. This work uses an intermediate karstified lab-scale physical model (IKLPM) to study fate and transport processes and assess viable tools to characterize heterogeneities in karst systems. Transport experiments are conducted in the IKLPM using step injections of calcium chloride, uranine, and rhodamine wt tracers. Temporal concentration distributions (TCDs) obtained from the experiments are analyzed using the method of moments and CXTFIT to quantify fate and transport parameters in the system at various flow rates. The spatial distribution of the estimated fate and transport parameters for the tracers revealed high variability related to preferential flow heterogeneities and scale dependence. Results are integrated to define spatially-variable transport regions within the system and assess their fate and transport characteristics.

Integrated Satellite Control in REIMEI (INDEX) Satellite

NASA Astrophysics Data System (ADS)

Fukuda, Seisuke; Mizuno, Takahide; Sakai, Shin-Ichiro; Fukushima, Yousuke; Saito, Hirobumi

REIMEI/INDEX (INnovative-technology Demonstration EXperiment) is a 70kg class small satellite which the Institute of Space and Astronautical Science, Japan Exploration Agency, ISAS/JAXA, has developed for observation of auroral small-scale dynamics as well as demonstration of advanced satellite technologies. An important engineering mission of REIMEI is integrated satellite control using commercial RISC CPUs with a triple voting system in order to ensure fault-tolerance against radiation hazards. Software modules concerning every satellite function, such as attitude control, data handling, and mission applications, work cooperatively so that highly sophisticated satellite control can be performed. In this paper, after a concept of the integrated satellite control is introduced, the Integrated Controller Unit (ICU) is described in detail. Also unique topics in developing the integrated control system are shown.

Development of Spreadsheet-Based Integrated Transaction Processing Systems and Financial Reporting Systems

NASA Astrophysics Data System (ADS)

Ariana, I. M.; Bagiada, I. M.

2018-01-01

Development of spreadsheet-based integrated transaction processing systems and financial reporting systems is intended to optimize the capabilities of spreadsheet in accounting data processing. The purpose of this study are: 1) to describe the spreadsheet-based integrated transaction processing systems and financial reporting systems; 2) to test its technical and operational feasibility. This study type is research and development. The main steps of study are: 1) needs analysis (need assessment); 2) developing spreadsheet-based integrated transaction processing systems and financial reporting systems; and 3) testing the feasibility of spreadsheet-based integrated transaction processing systems and financial reporting systems. The technical feasibility include the ability of hardware and operating systems to respond the application of accounting, simplicity and ease of use. Operational feasibility include the ability of users using accounting applications, the ability of accounting applications to produce information, and control applications of the accounting applications. The instrument used to assess the technical and operational feasibility of the systems is the expert perception questionnaire. The instrument uses 4 Likert scale, from 1 (strongly disagree) to 4 (strongly agree). Data were analyzed using percentage analysis by comparing the number of answers within one (1) item by the number of ideal answer within one (1) item. Spreadsheet-based integrated transaction processing systems and financial reporting systems integrate sales, purchases, and cash transaction processing systems to produce financial reports (statement of profit or loss and other comprehensive income, statement of changes in equity, statement of financial position, and statement of cash flows) and other reports. Spreadsheet-based integrated transaction processing systems and financial reporting systems is feasible from the technical aspects (87.50%) and operational aspects (84.17%).

KA-SB: from data integration to large scale reasoning

PubMed Central

Roldán-García, María del Mar; Navas-Delgado, Ismael; Kerzazi, Amine; Chniber, Othmane; Molina-Castro, Joaquín; Aldana-Montes, José F

2009-01-01

Background The analysis of information in the biological domain is usually focused on the analysis of data from single on-line data sources. Unfortunately, studying a biological process requires having access to disperse, heterogeneous, autonomous data sources. In this context, an analysis of the information is not possible without the integration of such data. Methods KA-SB is a querying and analysis system for final users based on combining a data integration solution with a reasoner. Thus, the tool has been created with a process divided into two steps: 1) KOMF, the Khaos Ontology-based Mediator Framework, is used to retrieve information from heterogeneous and distributed databases; 2) the integrated information is crystallized in a (persistent and high performance) reasoner (DBOWL). This information could be further analyzed later (by means of querying and reasoning). Results In this paper we present a novel system that combines the use of a mediation system with the reasoning capabilities of a large scale reasoner to provide a way of finding new knowledge and of analyzing the integrated information from different databases, which is retrieved as a set of ontology instances. This tool uses a graphical query interface to build user queries easily, which shows a graphical representation of the ontology and allows users o build queries by clicking on the ontology concepts. Conclusion These kinds of systems (based on KOMF) will provide users with very large amounts of information (interpreted as ontology instances once retrieved), which cannot be managed using traditional main memory-based reasoners. We propose a process for creating persistent and scalable knowledgebases from sets of OWL instances obtained by integrating heterogeneous data sources with KOMF. This process has been applied to develop a demo tool , which uses the BioPax Level 3 ontology as the integration schema, and integrates UNIPROT, KEGG, CHEBI, BRENDA and SABIORK databases. PMID:19796402

A multi-scale approach to designing therapeutics for tuberculosis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Linderman, Jennifer J.; Cilfone, Nicholas A.; Pienaar, Elsje

Approximately one third of the world’s population is infected with Mycobacterium tuberculosis. Limited information about how the immune system fights M. tuberculosis and what constitutes protection from the bacteria impact our ability to develop effective therapies for tuberculosis. We present an in vivo systems biology approach that integrates data from multiple model systems and over multiple length and time scales into a comprehensive multi-scale and multi-compartment view of the in vivo immune response to M. tuberculosis. Lastly, we describe computational models that can be used to study (a) immunomodulation with the cytokines tumor necrosis factor and interleukin 10, (b) oralmore » and inhaled antibiotics, and (c) the effect of vaccination.« less

A multi-scale approach to designing therapeutics for tuberculosis

DOE PAGES

Linderman, Jennifer J.; Cilfone, Nicholas A.; Pienaar, Elsje; ...

2015-04-20

Approximately one third of the world’s population is infected with Mycobacterium tuberculosis. Limited information about how the immune system fights M. tuberculosis and what constitutes protection from the bacteria impact our ability to develop effective therapies for tuberculosis. We present an in vivo systems biology approach that integrates data from multiple model systems and over multiple length and time scales into a comprehensive multi-scale and multi-compartment view of the in vivo immune response to M. tuberculosis. Lastly, we describe computational models that can be used to study (a) immunomodulation with the cytokines tumor necrosis factor and interleukin 10, (b) oralmore » and inhaled antibiotics, and (c) the effect of vaccination.« less

Integrated modelling of nitrate loads to coastal waters and land rent applied to catchment-scale water management.

PubMed

Refsgaard, A; Jacobsen, T; Jacobsen, B; Ørum, J-E

2007-01-01

The EU Water Framework Directive (WFD) requires an integrated approach to river basin management in order to meet environmental and ecological objectives. This paper presents concepts and full-scale application of an integrated modelling framework. The Ringkoebing Fjord basin is characterized by intensive agricultural production and leakage of nitrate constitute a major pollution problem with respect groundwater aquifers (drinking water), fresh surface water systems (water quality of lakes) and coastal receiving waters (eutrophication). The case study presented illustrates an advanced modelling approach applied in river basin management. Point sources (e.g. sewage treatment plant discharges) and distributed diffuse sources (nitrate leakage) are included to provide a modelling tool capable of simulating pollution transport from source to recipient to analyse the effects of specific, localized basin water management plans. The paper also includes a land rent modelling approach which can be used to choose the most cost-effective measures and the location of these measures. As a forerunner to the use of basin-scale models in WFD basin water management plans this project demonstrates the potential and limitations of comprehensive, integrated modelling tools.

Integrated low emissions cleanup system for direct coal-fueled turbines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lippert, T.E.; Newby, R.A.; Alvin, M.A.

1992-01-01

The Westinghouse Electric Corporation, Science Technology Center (W-STC) is developing an Integrated Low Emissions Cleanup (ILEC) concept for high-temperature gas cleaning to meet environmental standards, as well as to economical gas turbine life. The ILEC concept simultaneously controls sulfur, particulate, and alkali contaminants in high-pressure fuel gases or combustion gases at temperatures up to 1850[degrees]F for advanced power generation systems (PFBC, APFBC, IGCC, DCF7). The objective of this program is to demonstrate, at a bench scale, the conceptual, technical feasibility of the REC concept. The ELEC development program has a 3 phase structure: Phase 1 - laboratory-scale testing; phase 2more » - bench-scale equipment; design and fabrication; and phase 3 - bench-scale testing. Phase 1 laboratory testing has been completed. In Phase 1, entrained sulfur and alkali sorbent kinetics were measured and evaluated, and commercial-scale performance was projected. Related cold flow model testing has shown that gas-particle contacting within the ceramic barrier filter vessel will provide a good reactor environment. The Phase 1 test results and the commercial evaluation conducted in the Phase 1 program support the bench-scale facility testing to be performed in Phase 3. Phase 2 is nearing completion with the design and assembly of a modified, bench-scale test facility to demonstrate the technical feasibility of the ILEC features. This feasibility testing will be conducted in Phase 3.« less

Integrated low emissions cleanup system for direct coal-fueled turbines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lippert, T.E.; Newby, R.A.; Alvin, M.A.

1992-12-31

The Westinghouse Electric Corporation, Science & Technology Center (W-STC) is developing an Integrated Low Emissions Cleanup (ILEC) concept for high-temperature gas cleaning to meet environmental standards, as well as to economical gas turbine life. The ILEC concept simultaneously controls sulfur, particulate, and alkali contaminants in high-pressure fuel gases or combustion gases at temperatures up to 1850{degrees}F for advanced power generation systems (PFBC, APFBC, IGCC, DCF7). The objective of this program is to demonstrate, at a bench scale, the conceptual, technical feasibility of the REC concept. The ELEC development program has a 3 phase structure: Phase 1 - laboratory-scale testing; phasemore » 2 - bench-scale equipment; design and fabrication; and phase 3 - bench-scale testing. Phase 1 laboratory testing has been completed. In Phase 1, entrained sulfur and alkali sorbent kinetics were measured and evaluated, and commercial-scale performance was projected. Related cold flow model testing has shown that gas-particle contacting within the ceramic barrier filter vessel will provide a good reactor environment. The Phase 1 test results and the commercial evaluation conducted in the Phase 1 program support the bench-scale facility testing to be performed in Phase 3. Phase 2 is nearing completion with the design and assembly of a modified, bench-scale test facility to demonstrate the technical feasibility of the ILEC features. This feasibility testing will be conducted in Phase 3.« less

An intermediate-scale model for thermal hydrology in low-relief permafrost-affected landscapes

DOE PAGES

Jan, Ahmad; Coon, Ethan T.; Painter, Scott L.; ...

2017-07-10

Integrated surface/subsurface models for simulating the thermal hydrology of permafrost-affected regions in a warming climate have recently become available, but computational demands of those new process-rich simu- lation tools have thus far limited their applications to one-dimensional or small two-dimensional simulations. We present a mixed-dimensional model structure for efficiently simulating surface/subsurface thermal hydrology in low-relief permafrost regions at watershed scales. The approach replaces a full three-dimensional system with a two-dimensional overland thermal hydrology system and a family of one-dimensional vertical columns, where each column represents a fully coupled surface/subsurface thermal hydrology system without lateral flow. The system is then operatormore » split, sequentially updating the overland flow system without sources and the one-dimensional columns without lateral flows. We show that the app- roach is highly scalable, supports subcycling of different processes, and compares well with the corresponding fully three-dimensional representation at significantly less computational cost. Those advances enable recently developed representations of freezing soil physics to be coupled with thermal overland flow and surface energy balance at scales of 100s of meters. Furthermore developed and demonstrated for permafrost thermal hydrology, the mixed-dimensional model structure is applicable to integrated surface/subsurface thermal hydrology in general.« less

An Integrated Modeling and Simulation Methodology for Intelligent Systems Design and Testing

DTIC Science & Technology

2002-08-01

simulation and actual execution. KEYWORDS: Model Continuity, Modeling, Simulation, Experimental Frame, Real Time Systems , Intelligent Systems...the methodology for a stand-alone real time system. Then it will scale up to distributed real time systems . For both systems, step-wise simulation...MODEL CONTINUITY Intelligent real time systems monitor, respond to, or control, an external environment. This environment is connected to the digital

Regional-scale integration of hydrological and geophysical data using Bayesian sequential simulation: application to field data

NASA Astrophysics Data System (ADS)

Ruggeri, Paolo; Irving, James; Gloaguen, Erwan; Holliger, Klaus

2013-04-01

Significant progress has been made with regard to the quantitative integration of geophysical and hydrological data at the local scale. However, extending corresponding approaches to the regional scale still represents a major challenge, yet is critically important for the development of groundwater flow and contaminant transport models. To address this issue, we have developed a regional-scale hydrogeophysical data integration technique based on a two-step Bayesian sequential simulation procedure. The objective is to simulate the regional-scale distribution of a hydraulic parameter based on spatially exhaustive, but poorly resolved, measurements of a pertinent geophysical parameter and locally highly resolved, but spatially sparse, measurements of the considered geophysical and hydraulic parameters. To this end, our approach first involves linking the low- and high-resolution geophysical data via a downscaling procedure before relating the downscaled regional-scale geophysical data to the high-resolution hydraulic parameter field. We present the application of this methodology to a pertinent field scenario, where we consider collocated high-resolution measurements of the electrical conductivity, measured using a cone penetrometer testing (CPT) system, and the hydraulic conductivity, estimated from EM flowmeter and slug test measurements, in combination with low-resolution exhaustive electrical conductivity estimates obtained from dipole-dipole ERT meausurements.

Analysis of measurement system as the mechatronics system

NASA Astrophysics Data System (ADS)

Giniotis, V.; Grattan, K. T. V.; Rybokas, M.; Bručas, D.

2010-07-01

The paper deals with the mechatronic arrangement for angle measuring system application. The objects to be measured are the circular raster scales, rotary encoders and coded scales. The task of the measuring system is to determine the bias of angle measuring standard as the circular scale and to use the results for the error correction and accuracy improvement of metal cutting machines, coordinate measuring machines, robots, etc. The technical solutions are given with the application of active materials for smart piezoactuators implemented into the several positions of angular measuring equipment. Mechatronic measuring system is analysed as complex integrated system and some of its elements can be used as separate units. All these functional elements are described and commented in the paper with the diagrams and graphs of errors and examples of microdisplacement devices using the mechatronic elements.

A multidisciplinary approach to the development of low-cost high-performance lightwave networks

NASA Technical Reports Server (NTRS)

Maitan, Jacek; Harwit, Alex

1991-01-01

Our research focuses on high-speed distributed systems. We anticipate that our results will allow the fabrication of low-cost networks employing multi-gigabit-per-second data links for space and military applications. The recent development of high-speed low-cost photonic components and new generations of microprocessors creates an opportunity to develop advanced large-scale distributed information systems. These systems currently involve hundreds of thousands of nodes and are made up of components and communications links that may fail during operation. In order to realize these systems, research is needed into technologies that foster adaptability and scaleability. Self-organizing mechanisms are needed to integrate a working fabric of large-scale distributed systems. The challenge is to fuse theory, technology, and development methodologies to construct a cost-effective, efficient, large-scale system.

Investigating the Complex Chemistry of Functional Energy Storage Systems: The Need for an Integrative, Multiscale (Molecular to Mesoscale) Perspective.

PubMed

Abraham, Alyson; Housel, Lisa M; Lininger, Christianna N; Bock, David C; Jou, Jeffrey; Wang, Feng; West, Alan C; Marschilok, Amy C; Takeuchi, Kenneth J; Takeuchi, Esther S

2016-06-22

Electric energy storage systems such as batteries can significantly impact society in a variety of ways, including facilitating the widespread deployment of portable electronic devices, enabling the use of renewable energy generation for local off grid situations and providing the basis of highly efficient power grids integrated with energy production, large stationary batteries, and the excess capacity from electric vehicles. A critical challenge for electric energy storage is understanding the basic science associated with the gap between the usable output of energy storage systems and their theoretical energy contents. The goal of overcoming this inefficiency is to achieve more useful work (w) and minimize the generation of waste heat (q). Minimization of inefficiency can be approached at the macro level, where bulk parameters are identified and manipulated, with optimization as an ultimate goal. However, such a strategy may not provide insight toward the complexities of electric energy storage, especially the inherent heterogeneity of ion and electron flux contributing to the local resistances at numerous interfaces found at several scale lengths within a battery. Thus, the ability to predict and ultimately tune these complex systems to specific applications, both current and future, demands not just parametrization at the bulk scale but rather specific experimentation and understanding over multiple length scales within the same battery system, from the molecular scale to the mesoscale. Herein, we provide a case study examining the insights and implications from multiscale investigations of a prospective battery material, Fe3O4.

Exploring Land Use and Land Cover Change and Feedbacks in the Global Change Assessment Model

NASA Astrophysics Data System (ADS)

Chen, M.; Vernon, C. R.; Huang, M.; Calvin, K. V.; Le Page, Y.; Kraucunas, I.

2017-12-01

Land Use and Land Cover Change (LULCC) is a major driver of global and regional environmental change. Projections of land use change are thus an essential component in Integrated Assessment Models (IAMs) to study feedbacks between transformation of energy systems and land productivity under the context of climate change. However, the spatial scale of IAMs, e.g., the Global Change Assessment Model (GCAM), is typically larger than the scale of terrestrial processes in the human-Earth system, LULCC downscaling therefore becomes a critical linkage among these multi-scale and multi-sector processes. Parametric uncertainties in LULCC downscaling algorithms, however, have been under explored, especially in the context of how such uncertainties could propagate to affect energy systems in a changing climate. In this study, we use a LULCC downscaling model, Demeter, to downscale GCAM-based future land use scenarios into fine spatial scales, and explore the sensitivity of downscaled land allocations to key parameters. Land productivity estimates (e.g., biomass production and crop yield) based on the downscaled LULCC scenarios are then fed to GCAM to evaluate how energy systems might change due to altered water and carbon cycle dynamics and their interactions with the human system, , which would in turn affect future land use projections. We demonstrate that uncertainties in LULCC downscaling can result in significant differences in simulated scenarios, indicating the importance of quantifying parametric uncertainties in LULCC downscaling models for integrated assessment studies.

eScience for molecular-scale simulations and the eMinerals project.

PubMed

Salje, E K H; Artacho, E; Austen, K F; Bruin, R P; Calleja, M; Chappell, H F; Chiang, G-T; Dove, M T; Frame, I; Goodwin, A L; Kleese van Dam, K; Marmier, A; Parker, S C; Pruneda, J M; Todorov, I T; Trachenko, K; Tyer, R P; Walker, A M; White, T O H

2009-03-13

We review the work carried out within the eMinerals project to develop eScience solutions that facilitate a new generation of molecular-scale simulation work. Technological developments include integration of compute and data systems, developing of collaborative frameworks and new researcher-friendly tools for grid job submission, XML data representation, information delivery, metadata harvesting and metadata management. A number of diverse science applications will illustrate how these tools are being used for large parameter-sweep studies, an emerging type of study for which the integration of computing, data and collaboration is essential.

Development of analog watch with minute repeater

NASA Astrophysics Data System (ADS)

Okigami, Tomio; Aoyama, Shigeru; Osa, Takashi; Igarashi, Kiyotaka; Ikegami, Tomomi

A complementary metal oxide semiconductor with large scale integration was developed for an electronic minute repeater. It is equipped with the synthetic struck sound circuit to generate natural struck sound necessary for the minute repeater. This circuit consists of an envelope curve drawing circuit, frequency mixer, polyphonic mixer, and booster circuit made by using analog circuit technology. This large scale integration is a single chip microcomputer with motor drivers and input ports in addition to the synthetic struck sound circuit, and it is possible to make an electronic system of minute repeater at a very low cost in comparison with the conventional type.

Data registration and integration requirements for severe storms research

NASA Technical Reports Server (NTRS)

Dalton, J. T.

1982-01-01

Severe storms research is characterized by temporal scales ranging from minutes (for thunderstorms and tornadoes) to hours (for hurricanes and extra-tropical cyclones). Spatial scales range from tens to hundreds of kilometers. Sources of observational data include a variety of ground based and satellite systems. Requirements for registration and intercomparison of data from these various sources are examined and the potential for operational forecasting application of techniques resulting from the research is discussed. The sensor characteristics and processing procedures relating to the overlay and integrated analysis of satellite and surface observations for severe storms research are reviewed.

Challenges in scaling up biofuels infrastructure.

PubMed

Richard, Tom L

2010-08-13

Rapid growth in demand for lignocellulosic bioenergy will require major changes in supply chain infrastructure. Even with densification and preprocessing, transport volumes by mid-century are likely to exceed the combined capacity of current agricultural and energy supply chains, including grain, petroleum, and coal. Efficient supply chains can be achieved through decentralized conversion processes that facilitate local sourcing, satellite preprocessing and densification for long-distance transport, and business models that reward biomass growers both nearby and afar. Integrated systems that are cost-effective and energy-efficient will require new ways of thinking about agriculture, energy infrastructure, and rural economic development. Implementing these integrated systems will require innovation and investment in novel technologies, efficient value chains, and socioeconomic and policy frameworks; all are needed to support an expanded biofuels infrastructure that can meet the challenges of scale.

Multiscale mechanobiology: computational models for integrating molecules to multicellular systems

PubMed Central

Mak, Michael; Kim, Taeyoon

2015-01-01

Mechanical signals exist throughout the biological landscape. Across all scales, these signals, in the form of force, stiffness, and deformations, are generated and processed, resulting in an active mechanobiological circuit that controls many fundamental aspects of life, from protein unfolding and cytoskeletal remodeling to collective cell motions. The multiple scales and complex feedback involved present a challenge for fully understanding the nature of this circuit, particularly in development and disease in which it has been implicated. Computational models that accurately predict and are based on experimental data enable a means to integrate basic principles and explore fine details of mechanosensing and mechanotransduction in and across all levels of biological systems. Here we review recent advances in these models along with supporting and emerging experimental findings. PMID:26019013

Nanoscale integration is the next frontier for nanotechnology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Picraux, Samuel T

2009-01-01

Nanoscale integration of materials and structures is the next critical step to exploit the promise of nanomaterials. Many novel and fascinating properties have been revealed for nanostructured materials. But if nanotechnology is to live up to its promise we must incorporate these nanoscale building blocks into functional systems that connect to the micro- and macroscale world. To do this we will inevitably need to understand and exploit the resulting combined unique properties of these integrated nanosystems. Much science waits to be discovered in the process. Nanoscale integration extends from the synthesis and fabrication of individual nanoscale building blocks, to themore » assembly of these building blocks into composite structures, and finally to the formation of complex functional systems. As illustrated in Figure 1, the building blocks may be homogeneous or heterogeneous, the composite materials may be nanocomposite or patterned structures, and the functional systems will involve additional combinations of materials. Nanoscale integration involves assembling diverse nanoscale materials across length scales to design and achieve new properties and functionality. At each stage size-dependent properties, the influence of surfaces in close proximity, and a multitude of interfaces all come into play. Whether the final system involves coherent electrons in a quantum computing approach, the combined flow of phonons and electrons for a high efficiency thermoelectric micro-generator, or a molecular recognition structure for bio-sensing, the combined effects of size, surface, and interface will be critical. In essence, one wants to combine the novel functions available through nanoscale science to achieve unique multi-functionalities not available in bulk materials. Perhaps the best-known example of integration is that of combining electronic components together into very large scale integrated circuits (VLSI). The integrated circuit has revolutionized electronics in many ways, from exploiting field-effect transistor devices and low power complementary logic to enable the electronic watch and hand calculator in the 1970's, to today's microprocessors and memories with billions of devices and a computational power not imagined a few decades ago. The manipulation of charges on a chip, the new concepts in combining devices for logic functions, and the new approaches to computation, information processing, and imaging have all emerged from Kilby and Noyce's simple concept of integrating devices on a single chip. Moving from hard to soft materials, a second more recent example of integration is the DNA microarray. These microarrays, with up to millions of elements in a planar array that can be optically read out, can simultaneously measure the expression of 10's of thousands of genes to study the effects of disease and treatment, or screen for single nucleotide polymorphisms for uses ranging from forensics to predisposition to disease. While still at an early stage, microarrays have revolutionized biosciences by providing the means to interrogate the complex genetic control of biological functions. Just as integrated circuits and microarrays have led to completely new functionalities and performance, the integration of nanoscale materials and structures is anticipated to lead to new performance and enable the design of new functionalities not previously envisioned. The fundamental questions underlying integration go beyond just complex fabrication or the engineering of known solutions; they lead to new discoveries and new science. The scientific challenges around nanoscale integration necessitate the development of new knowledge that is central to the advance of nanotechnology. To move forward one must address key science questions that arise in nanoscience integration and go beyond a single system or materials area. New science and discoveries especially await around three questions. How does one: (1) Control energy transfer and other interactions across interfaces and over mUltiple length scales? (2) Understand and control the interactions between nanoscale building blocks to assemble specific integrated structures? (3) Design and exploit interactions within assembled structures to achieve new properties and specific functionalities? These high level questions can serve to drive research, and to advance understanding of the complex phenomena and multifunctionality that may emerge from integration. For example, in photonics there is considerable effort to understand and control the response of nanoscale conducting structures on dielectrics, to allow one to localize, manipulate, and control electromagnetic energy in integrated systems such as in the field known as metamaterials. Essential to this area is a fundamental understanding of energy transfer across multiple length scales (question 1 above).« less

Multiloop Integral System Test (MIST): MIST Facility Functional Specification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Habib, T F; Koksal, C G; Moskal, T E

1991-04-01

The Multiloop Integral System Test (MIST) is part of a multiphase program started in 1983 to address small-break loss-of-coolant accidents (SBLOCAs) specific to Babcock and Wilcox designed plants. MIST is sponsored by the US Nuclear Regulatory Commission, the Babcock Wilcox Owners Group, the Electric Power Research Institute, and Babcock and Wilcox. The unique features of the Babcock and Wilcox design, specifically the hot leg U-bends and steam generators, prevented the use of existing integral system data or existing integral facilities to address the thermal-hydraulic SBLOCA questions. MIST was specifically designed and constructed for this program, and an existing facility --more » the Once Through Integral System (OTIS) -- was also used. Data from MIST and OTIS are used to benchmark the adequacy of system codes, such as RELAP5 and TRAC, for predicting abnormal plant transients. The MIST Functional Specification documents as-built design features, dimensions, instrumentation, and test approach. It also presents the scaling basis for the facility and serves to define the scope of work for the facility design and construction. 13 refs., 112 figs., 38 tabs.« less

Hierarchical Address Event Routing for Reconfigurable Large-Scale Neuromorphic Systems.

PubMed

Park, Jongkil; Yu, Theodore; Joshi, Siddharth; Maier, Christoph; Cauwenberghs, Gert

2017-10-01

We present a hierarchical address-event routing (HiAER) architecture for scalable communication of neural and synaptic spike events between neuromorphic processors, implemented with five Xilinx Spartan-6 field-programmable gate arrays and four custom analog neuromophic integrated circuits serving 262k neurons and 262M synapses. The architecture extends the single-bus address-event representation protocol to a hierarchy of multiple nested buses, routing events across increasing scales of spatial distance. The HiAER protocol provides individually programmable axonal delay in addition to strength for each synapse, lending itself toward biologically plausible neural network architectures, and scales across a range of hierarchies suitable for multichip and multiboard systems in reconfigurable large-scale neuromorphic systems. We show approximately linear scaling of net global synaptic event throughput with number of routing nodes in the network, at 3.6×10 7 synaptic events per second per 16k-neuron node in the hierarchy.

Scale development of safety management system evaluation for the airline industry.

PubMed

Chen, Ching-Fu; Chen, Shu-Chuan

2012-07-01

The airline industry relies on the implementation of Safety Management System (SMS) to integrate safety policies and augment safety performance at both organizational and individual levels. Although there are various degrees of SMS implementation in practice, a comprehensive scale measuring the essential dimensions of SMS is still lacking. This paper thus aims to develop an SMS measurement scale from the perspective of aviation experts and airline managers to evaluate the performance of company's safety management system, by adopting Schwab's (1980) three-stage scale development procedure. The results reveal a five-factor structure consisting of 23 items. The five factors include documentation and commands, safety promotion and training, executive management commitment, emergency preparedness and response plan and safety management policy. The implications of this SMS evaluation scale for practitioners and future research are discussed. Copyright © 2012 Elsevier Ltd. All rights reserved.

Recent Progresses in Incorporating Human Land-Water Management into Global Land Surface Models Toward Their Integration into Earth System Models

NASA Technical Reports Server (NTRS)

Pokhrel, Yadu N.; Hanasaki, Naota; Wada, Yoshihide; Kim, Hyungjun

2016-01-01

The global water cycle has been profoundly affected by human land-water management. As the changes in the water cycle on land can affect the functioning of a wide range of biophysical and biogeochemical processes of the Earth system, it is essential to represent human land-water management in Earth system models (ESMs). During the recent past, noteworthy progress has been made in large-scale modeling of human impacts on the water cycle but sufficient advancements have not yet been made in integrating the newly developed schemes into ESMs. This study reviews the progresses made in incorporating human factors in large-scale hydrological models and their integration into ESMs. The study focuses primarily on the recent advancements and existing challenges in incorporating human impacts in global land surface models (LSMs) as a way forward to the development of ESMs with humans as integral components, but a brief review of global hydrological models (GHMs) is also provided. The study begins with the general overview of human impacts on the water cycle. Then, the algorithms currently employed to represent irrigation, reservoir operation, and groundwater pumping are discussed. Next, methodological deficiencies in current modeling approaches and existing challenges are identified. Furthermore, light is shed on the sources of uncertainties associated with model parameterizations, grid resolution, and datasets used for forcing and validation. Finally, representing human land-water management in LSMs is highlighted as an important research direction toward developing integrated models using ESM frameworks for the holistic study of human-water interactions within the Earths system.

An integrated multiscale river basin observing system in the Heihe River Basin, northwest China

NASA Astrophysics Data System (ADS)

Li, X.; Liu, S.; Xiao, Q.; Ma, M.; Jin, R.; Che, T.

2015-12-01

Using the watershed as the unit to establish an integrated watershed observing system has been an important trend in integrated eco-hydrologic studies in the past ten years. Thus far, a relatively comprehensive watershed observing system has been established in the Heihe River Basin, northwest China. In addition, two comprehensive remote sensing hydrology experiments have been conducted sequentially in the Heihe River Basin, including the Watershed Allied Telemetry Experimental Research (WATER) (2007-2010) and the Heihe Watershed Allied Telemetry Experimental Research (HiWATER) (2012-2015). Among these two experiments, an important result of WATER has been the generation of some multi-scale, high-quality comprehensive datasets, which have greatly supported the development, improvement and validation of a series of ecological, hydrological and quantitative remote-sensing models. The goal of a breakthrough for solving the "data bottleneck" problem has been achieved. HiWATER was initiated in 2012. This project has established a world-class hydrological and meteorological observation network, a flux measurement matrix and an eco-hydrological wireless sensor network. A set of super high-resolution airborne remote-sensing data has also been obtained. In addition, there has been important progress with regard to the scaling research. Furthermore, the automatic acquisition, transmission, quality control and remote control of the observational data has been realized through the use of wireless sensor network technology. The observation and information systems have been highly integrated, which will provide a solid foundation for establishing a research platform that integrates observation, data management, model simulation, scenario analysis and decision-making support to foster 21st-century watershed science in China.

The Parallel System for Integrating Impact Models and Sectors (pSIMS)

NASA Technical Reports Server (NTRS)

Elliott, Joshua; Kelly, David; Chryssanthacopoulos, James; Glotter, Michael; Jhunjhnuwala, Kanika; Best, Neil; Wilde, Michael; Foster, Ian

2014-01-01

We present a framework for massively parallel climate impact simulations: the parallel System for Integrating Impact Models and Sectors (pSIMS). This framework comprises a) tools for ingesting and converting large amounts of data to a versatile datatype based on a common geospatial grid; b) tools for translating this datatype into custom formats for site-based models; c) a scalable parallel framework for performing large ensemble simulations, using any one of a number of different impacts models, on clusters, supercomputers, distributed grids, or clouds; d) tools and data standards for reformatting outputs to common datatypes for analysis and visualization; and e) methodologies for aggregating these datatypes to arbitrary spatial scales such as administrative and environmental demarcations. By automating many time-consuming and error-prone aspects of large-scale climate impacts studies, pSIMS accelerates computational research, encourages model intercomparison, and enhances reproducibility of simulation results. We present the pSIMS design and use example assessments to demonstrate its multi-model, multi-scale, and multi-sector versatility.

Molecular dynamics at low time resolution.

PubMed

Faccioli, P

2010-10-28

The internal dynamics of macromolecular systems is characterized by widely separated time scales, ranging from fraction of picoseconds to nanoseconds. In ordinary molecular dynamics simulations, the elementary time step Δt used to integrate the equation of motion needs to be chosen much smaller of the shortest time scale in order not to cut-off physical effects. We show that in systems obeying the overdamped Langevin equation, it is possible to systematically correct for such discretization errors. This is done by analytically averaging out the fast molecular dynamics which occurs at time scales smaller than Δt, using a renormalization group based technique. Such a procedure gives raise to a time-dependent calculable correction to the diffusion coefficient. The resulting effective Langevin equation describes by construction the same long-time dynamics, but has a lower time resolution power, hence it can be integrated using larger time steps Δt. We illustrate and validate this method by studying the diffusion of a point-particle in a one-dimensional toy model and the denaturation of a protein.

Organizational Agility and Complex Enterprise System Innovations: A Mixed Methods Study of the Effects of Enterprise Systems on Organizational Agility

ERIC Educational Resources Information Center

Kharabe, Amol T.

2012-01-01

Over the last two decades, firms have operated in "increasingly" accelerated "high-velocity" dynamic markets, which require them to become "agile." During the same time frame, firms have increasingly deployed complex enterprise systems--large-scale packaged software "innovations" that integrate and automate…

Practical experience with full-scale structured sheet media (SSM) integrated fixed-film activated sludge (IFAS) systems for nitrification.

PubMed

Li, Hua; Zhu, Jia; Flamming, James J; O'Connell, Jack; Shrader, Michael

2015-01-01

Many wastewater treatment plants in the USA, which were originally designed as secondary treatment systems with no or partial nitrification requirements, are facing increased flows, loads, and more stringent ammonia discharge limits. Plant expansion is often not cost-effective due to either high construction costs or lack of land. Under these circumstances, integrated fixed-film activated sludge (IFAS) systems using both suspended growth and biofilms that grow attached to a fixed plastic structured sheet media are found to be a viable solution for solving the challenges. Multiple plants have been retrofitted with such IFAS systems in the past few years. The system has proven to be efficient and reliable in achieving not only consistent nitrification, but also enhanced bio-chemical oxygen demand removal and sludge settling characteristics. This paper presents long-term practical experiences with the IFAS system design, operation and maintenance, and performance for three full-scale plants with distinct processes; that is, a trickling filter/solids contact process, a conventional plug flow activated sludge process and an extended aeration process.

Integrated pretreatment and desalination by electrocoagulation (EC)-ion concentration polarization (ICP) hybrid.

PubMed

Choi, Siwon; Kim, Bumjoo; Han, Jongyoon

2017-06-13

Conventional water treatment process is composed of multiple stages, including desalination (salt removal) and pre/post-treatment of desalination to remove particles, chemicals, and other potential foulants for desalination. In this work, we developed a microfluidic proof-of-concept for a single device water treatment system, which removes both salt ions and non-salt contaminants. Our system combines electrocoagulation (EC), a versatile contaminant removal process, and ion concentration polarization (ICP) desalination, which is an electromembrane desalination process. We demonstrated a continuous EC-ICP operation that removed >95% of suspended solids and reduced the salinity from brackish range (20 mM NaCl) to a potable level (<8.6 mM NaCl). We also demonstrated that our system is flexible in terms of the type and concentration of contaminants it can handle. Combining two different electrochemical processes into a single system, we can reduce unnecessary voltage drop by having a shared anode, and achieve both seamless integration and energy efficient operation. Our system will find applications as a small-scale water treatment system, if properly scaled up in the future.

Multilayer network modeling of integrated biological systems. Comment on "Network science of biological systems at different scales: A review" by Gosak et al.

NASA Astrophysics Data System (ADS)

De Domenico, Manlio

2018-03-01

Biological systems, from a cell to the human brain, are inherently complex. A powerful representation of such systems, described by an intricate web of relationships across multiple scales, is provided by complex networks. Recently, several studies are highlighting how simple networks - obtained by aggregating or neglecting temporal or categorical description of biological data - are not able to account for the richness of information characterizing biological systems. More complex models, namely multilayer networks, are needed to account for interdependencies, often varying across time, of biological interacting units within a cell, a tissue or parts of an organism.

Evolution of the Tropical Cyclone Integrated Data Exchange And Analysis System (TC-IDEAS)

NASA Technical Reports Server (NTRS)

Turk, J.; Chao, Y.; Haddad, Z.; Hristova-Veleva, S.; Knosp, B.; Lambrigtsen, B.; Li, P.; Licata, S.; Poulsen, W.; Su, H.;

Scaled Jump in Gravity-Reduced Virtual Environments.

PubMed

Kim, MyoungGon; Cho, Sunglk; Tran, Tanh Quang; Kim, Seong-Pil; Kwon, Ohung; Han, JungHyun

2017-04-01

The reduced gravity experienced in lunar or Martian surfaces can be simulated on the earth using a cable-driven system, where the cable lifts a person to reduce his or her weight. This paper presents a novel cable-driven system designed for the purpose. It is integrated with a head-mounted display and a motion capture system. Focusing on jump motion within the system, this paper proposes to scale the jump and reports the experiments made for quantifying the extent to which a jump can be scaled without the discrepancy between physical and virtual jumps being noticed by the user. With the tolerable range of scaling computed from these experiments, an application named retargeted jump is developed, where a user can jump up onto virtual objects while physically jumping in the real-world flat floor. The core techniques presented in this paper can be extended to develop extreme-sport simulators such as parasailing and skydiving.

Integration and dynamics of a renewable regenerative hydrogen fuel cell system

NASA Astrophysics Data System (ADS)

Bergen, Alvin Peter

2008-10-01

This thesis explores the integration and dynamics of residential scale renewable-regenerative energy systems which employ hydrogen for energy buffering. The development of the Integrated Renewable Energy Experiment (IRENE) test-bed is presented. IRENE is a laboratory-scale distributed energy system with a modular structure which can be readily re-configured to test newly developed components for generic regenerative systems. Key aspects include renewable energy conversion, electrolysis, hydrogen and electricity storage, and fuel cells. A special design feature of this test bed is the ability to accept dynamic inputs from and provide dynamic loads to real devices as well as from simulated energy sources/sinks. The integration issues encountered while developing IRENE and innovative solutions devised to overcome these barriers are discussed. Renewable energy systems that employ a regenerative approach to enable intermittent energy sources to service time varying loads rely on the efficient transfer of energy through the storage media. Experiments were conducted to evaluate the performance of the hydrogen energy buffer under a range of dynamic operating conditions. Results indicate that the operating characteristics of the electrolyser under transient conditions limit the production of hydrogen from excess renewable input power. These characteristics must be considered when designing or modeling a renewable-regenerative system. Strategies to mitigate performance degradation due to interruptions in the renewable power supply are discussed. Experiments were conducted to determine the response of the IRENE system to operating conditions that are representative of a residential scale, solar based, renewable-regenerative system. A control algorithm, employing bus voltage constraints and device current limitations, was developed to guide system operation. Results for a two week operating period that indicate that the system response is very dynamic but repeatable are presented. The overall system energy balance reveals that the energy input from the renewable source was sufficient to meet the demand load and generate a net surplus of hydrogen. The energy loss associated with the various system components as well as a breakdown of the unused renewable energy input is presented. In general, the research indicates that the technical challenges associated with hydrogen energy buffing can be overcome, but the round trip efficiency for the current technologies is low at only 22 percent.

WikiPEATia - a web based platform for assembling peatland data through ‘crowd sourcing’

NASA Astrophysics Data System (ADS)

Wisser, D.; Glidden, S.; Fieseher, C.; Treat, C. C.; Routhier, M.; Frolking, S. E.

2009-12-01

The Earth System Science community is realizing that peatlands are an important and unique terrestrial ecosystem that has not yet been well-integrated into large-scale earth system analyses. A major hurdle is the lack of accessible, geospatial data of peatland distribution, coupled with data on peatland properties (e.g., vegetation composition, peat depth, basal dates, soil chemistry, peatland class) at the global scale. This data, however, is available at the local scale. Although a comprehensive global database on peatlands probably lags similar data on more economically important ecosystems such as forests, grasslands, croplands, a large amount of field data have been collected over the past several decades. A few efforts have been made to map peatlands at large scales but existing data have not been assembled into a single geospatial database that is publicly accessible or do not depict data with a level of detail that is needed in the Earth System Science Community. A global peatland database would contribute to advances in a number of research fields such as hydrology, vegetation and ecosystem modeling, permafrost modeling, and earth system modeling. We present a Web 2.0 approach that uses state-of-the-art webserver and innovative online mapping technologies and is designed to create such a global database through ‘crowd-sourcing’. Primary functions of the online system include form-driven textual user input of peatland research metadata, spatial data input of peatland areas via a mapping interface, database editing and querying editing capabilities, as well as advanced visualization and data analysis tools. WikiPEATia provides an integrated information technology platform for assembling, integrating, and posting peatland-related geospatial datasets facilitates and encourages research community involvement. A successful effort will make existing peatland data much more useful to the research community, and will help to identify significant data gaps.

Multimodal integration of micro-Doppler sonar and auditory signals for behavior classification with convolutional networks.

PubMed

Dura-Bernal, Salvador; Garreau, Guillaume; Georgiou, Julius; Andreou, Andreas G; Denham, Susan L; Wennekers, Thomas

2013-10-01

The ability to recognize the behavior of individuals is of great interest in the general field of safety (e.g. building security, crowd control, transport analysis, independent living for the elderly). Here we report a new real-time acoustic system for human action and behavior recognition that integrates passive audio and active micro-Doppler sonar signatures over multiple time scales. The system architecture is based on a six-layer convolutional neural network, trained and evaluated using a dataset of 10 subjects performing seven different behaviors. Probabilistic combination of system output through time for each modality separately yields 94% (passive audio) and 91% (micro-Doppler sonar) correct behavior classification; probabilistic multimodal integration increases classification performance to 98%. This study supports the efficacy of micro-Doppler sonar systems in characterizing human actions, which can then be efficiently classified using ConvNets. It also demonstrates that the integration of multiple sources of acoustic information can significantly improve the system's performance.

Picture Archiving and Communication System (PACS) implementation, integration & benefits in an integrated health system.

PubMed

Mansoori, Bahar; Erhard, Karen K; Sunshine, Jeffrey L

2012-02-01

The availability of the Picture Archiving and Communication System (PACS) has revolutionized the practice of radiology in the past two decades and has shown to eventually increase productivity in radiology and medicine. PACS implementation and integration may bring along numerous unexpected issues, particularly in a large-scale enterprise. To achieve a successful PACS implementation, identifying the critical success and failure factors is essential. This article provides an overview of the process of implementing and integrating PACS in a comprehensive health system comprising an academic core hospital and numerous community hospitals. Important issues are addressed, touching all stages from planning to operation and training. The impact of an enterprise-wide radiology information system and PACS at the academic medical center (four specialty hospitals), in six additional community hospitals, and in all associated outpatient clinics as well as the implications on the productivity and efficiency of the entire enterprise are presented. Copyright © 2012 AUR. Published by Elsevier Inc. All rights reserved.

SCIENCE FOR INTEGRATED WATERSHED MANAGEMENT: A MULTI-SCALE EXPERIMENTAL CASE STUDY LINKING LAND USE MANAGEMENT PRACTICES AND WATER QUALITY IN SOUTHERN OHIO

EPA Science Inventory

Although it is routine for watershed management programs to coincide the monitoring of land use impacts and water quality at different spatial scales, rarely are the data collected in a manner to elucidate the linkages among ecological systems across a drainage network. There rem...

An integrated assessment of location-dependent scaling for microalgae biofuel production facilities

DOE PAGES

Coleman, André M.; Abodeely, Jared M.; Skaggs, Richard L.; ...

2014-06-19

Successful development of a large-scale microalgae-based biofuels industry requires comprehensive analysis and understanding of the feedstock supply chain—from facility siting and design through processing and upgrading of the feedstock to a fuel product. The evolution from pilot-scale production facilities to energy-scale operations presents many multi-disciplinary challenges, including a sustainable supply of water and nutrients, operational and infrastructure logistics, and economic competitiveness with petroleum-based fuels. These challenges are partially addressed by applying the Integrated Assessment Framework (IAF) – an integrated multi-scale modeling, analysis, and data management suite – to address key issues in developing and operating an open-pond microalgae production facility.more » This is done by analyzing how variability and uncertainty over space and through time affect feedstock production rates, and determining the site-specific “optimum” facility scale to minimize capital and operational expenses. This approach explicitly and systematically assesses the interdependence of biofuel production potential, associated resource requirements, and production system design trade-offs. To provide a baseline analysis, the IAF was applied in this paper to a set of sites in the southeastern U.S. with the potential to cumulatively produce 5 billion gallons per year. Finally, the results indicate costs can be reduced by scaling downstream processing capabilities to fit site-specific growing conditions, available and economically viable resources, and specific microalgal strains.« less

Utility of the Community Integration Questionnaire in a sample of adults with neurological and neuropsychiatric disorders receiving prevocational training.

PubMed

Tomaszewski, Robert; Mitrushina, Maura

2016-01-01

To investigate utility of the Community Integration Questionnaire (CIQ) in a mixed sample of adults with neurological and neuropsychiatric disorders. Cross-sectional, interview-based study. Participants were community-dwelling adults with disabilities resulting from neurological and neuropsychiatric disorders (N = 54), who participated in a pre-vocational readiness and social skills training program. Psychometric properties of the Community Integration Questionnaire (CIQ) were assessed and validated against Mayo-Portland Adaptability Inventory (MPAI) and The Problem Checklist from the New York University Head Injury Family Interview (PCL). Based on the revised scoring procedures, psychometric properties of the CIQ Home Competency scale were excellent, followed by the Total score and Social Integration scale. Productive Activity scale had low content validity and a weak association with the total score. Convergent and discriminant validity of the CIQ were demonstrated by correlation patterns with MPAI scales in the expected direction. Significant relationship was found with PCL Physical/Dependency scale. Significant associations were found with sex, living status, and record of subsequent employment. The results provide support for the use of the CIQ as a measure of participation in individuals with neurological and neuropsychiatric diagnoses and resulting disabilities. An important goal of rehabilitation and training programs for individuals with dysfunction of the central nervous system is to promote their participation in social, vocational, and domestic activities. The Community Integration Questionnaire (CIQ) is a brief and efficient instrument for measuring these participation domains. This study demonstrated good psychometric properties and high utility of the CIQ in a sample of 54 individuals participating in a prevocational training program.

Supporting BPMN choreography with system integration artefacts for enterprise process collaboration

NASA Astrophysics Data System (ADS)

Nie, Hongchao; Lu, Xudong; Duan, Huilong

2014-07-01

Business Process Model and Notation (BPMN) choreography modelling depicts externally visible message exchanges between collaborating processes of enterprise information systems. Implementation of choreography relies on designing system integration solutions to realise message exchanges between independently developed systems. Enterprise integration patterns (EIPs) are widely accepted artefacts to design integration solutions. If the choreography model represents coordination requirements between processes with behaviour mismatches, the integration designer needs to analyse the routing requirements and address these requirements by manually designing EIP message routers. As collaboration scales and complexity increases, manual design becomes inefficient. Thus, the research problem of this paper is to explore a method to automatically identify routing requirements from BPMN choreography model and to accordingly design routing in the integration solution. To achieve this goal, recurring behaviour mismatch scenarios are analysed as patterns, and corresponding solutions are proposed as EIP routers. Using this method, a choreography model can be analysed by computer to identify occurrences of mismatch patterns, leading to corresponding router selection. A case study demonstrates that the proposed method enables computer-assisted integration design to implement choreography. A further experiment reveals that the method is effective to improve the design quality and reduce time cost.

Heating in Integrable Time-Periodic Systems

NASA Astrophysics Data System (ADS)

Ishii, Takashi; Kuwahara, Tomotaka; Mori, Takashi; Hatano, Naomichi

2018-06-01

We investigate a heating phenomenon in periodically driven integrable systems that can be mapped to free-fermion models. We find that heating to the high-temperature state, which is a typical scenario in nonintegrable systems, can also appear in integrable time-periodic systems; the amount of energy absorption rises drastically near a frequency threshold where the Floquet-Magnus expansion diverges. As the driving period increases, we also observe that the effective temperatures of the generalized Gibbs ensemble for conserved quantities go to infinity. By the use of the scaling analysis, we reveal that, in the limit of infinite system size and driving period, the steady state after a long time is equivalent to the infinite-temperature state. We obtain the asymptotic behavior L-1 and T-2 as to how the steady state approaches the infinite-temperature state as the system size L and the driving period T increase.

Phosphorus transfer in surface runoff from intensive pasture systems at various scales: a review.

PubMed

Dougherty, Warwick J; Fleming, Nigel K; Cox, Jim W; Chittleborough, David J

2004-01-01

Phosphorus transfer in runoff from intensive pasture systems has been extensively researched at a range of scales. However, integration of data from the range of scales has been limited. This paper presents a conceptual model of P transfer that incorporates landscape effects and reviews the research relating to P transfer at a range of scales in light of this model. The contribution of inorganic P sources to P transfer is relatively well understood, but the contribution of organic P to P transfer is still relatively poorly defined. Phosphorus transfer has been studied at laboratory, profile, plot, field, and watershed scales. The majority of research investigating the processes of P transfer (as distinct from merely quantifying P transfer) has been undertaken at the plot scale. However, there is a growing need to integrate data gathered at a range of scales so that more effective strategies to reduce P transfer can be identified. This has been hindered by the lack of a clear conceptual framework to describe differences in the processes of P transfer at the various scales. The interaction of hydrological (transport) factors with P source factors, and their relationship to scale, require further examination. Runoff-generating areas are highly variable, both temporally and spatially. Improvement in the understanding and identification of these areas will contribute to increased effectiveness of strategies aimed at reducing P transfers in runoff. A thorough consideration of scale effects using the conceptual model of P transfer outlined in this paper will facilitate the development of improved strategies for reducing P losses in runoff.

AgMIP's Transdisciplinary Agricultural Systems Approach to Regional Integrated Assessment of Climate Impacts, Vulnerability, and Adaptation

NASA Technical Reports Server (NTRS)

Antle, John M.; Valdivia, Roberto O.; Boote, Kenneth J.; Janssen, Sander; Jones, James W.; Porter, Cheryl H.; Rosenzweig, Cynthia; Ruane, Alexander C.; Thorburn, Peter J.

2015-01-01

This chapter describes methods developed by the Agricultural Model Intercomparison and Improvement Project (AgMIP) to implement a transdisciplinary, systems-based approach for regional-scale (local to national) integrated assessment of agricultural systems under future climate, biophysical, and socio-economic conditions. These methods were used by the AgMIP regional research teams in Sub-Saharan Africa and South Asia to implement the analyses reported in their respective chapters of this book. Additional technical details are provided in Appendix 1.The principal goal that motivates AgMIP's regional integrated assessment (RIA) methodology is to provide scientifically rigorous information needed to support improved decision-making by various stakeholders, ranging from local to national and international non-governmental and governmental organizations.

Ictalurids in Iowa’s streams and rivers: Status, distribution, and relationships with biotic integrity

USGS Publications Warehouse

Sindt, Anthony R.; Fischer, Jesse R.; Quist, Michael C.; Pierce, Clay

2011-01-01

Anthropogenic alterations to Iowa’s landscape have greatly altered lotic systems with consequent effects on the biodiversity of freshwater fauna. Ictalurids are a diverse group of fishes and play an important ecological role in aquatic ecosystems. However, little is known about their distribution and status in lotic systems throughout Iowa. The purpose of this study was to describe the distribution of ictalurids in Iowa and examine their relationship with ecological integrity of streams and rivers. Historical data (i.e., 1884–2002) compiled for the Iowa Aquatic Gap Analysis Project (IAGAP) were used to detect declines in the distribution of ictalurids in Iowa streams and rivers at stream segment and watershed scales. Eight variables characterizing ictalurid assemblages were used to evaluate relationships with index of biotic integrity (IBI) ratings. Comparisons of recent and historic data from the IAGAP database indicated that 9 of Iowa’s 10 ictalurid species experienced distribution declines at one or more spatial scales. Analysis of variance indicated that ictalurid assemblages differed among samples with different IBI ratings. Specifically, total ictalurid, sensitive ictalurid, and Noturus spp. richness increased as IBI ratings increased. Results indicate declining ictalurid species distributions and biotic integrity are related, and management strategies aimed to improve habitat and increase biotic integrity will benefit ictalurid species.

InfoSymbiotics/DDDAS - The power of Dynamic Data Driven Applications Systems for New Capabilities in Environmental -, Geo-, and Space- Sciences

NASA Astrophysics Data System (ADS)

Darema, F.

2016-12-01

InfoSymbiotics/DDDAS embodies the power of Dynamic Data Driven Applications Systems (DDDAS), a concept whereby an executing application model is dynamically integrated, in a feed-back loop, with the real-time data-acquisition and control components, as well as other data sources of the application system. Advanced capabilities can be created through such new computational approaches in modeling and simulations, and in instrumentation methods, and include: enhancing the accuracy of the application model; speeding-up the computation to allow faster and more comprehensive models of a system, and create decision support systems with the accuracy of full-scale simulations; in addition, the notion of controlling instrumentation processes by the executing application results in more efficient management of application-data and addresses challenges of how to architect and dynamically manage large sets of heterogeneous sensors and controllers, an advance over the static and ad-hoc ways of today - with DDDAS these sets of resources can be managed adaptively and in optimized ways. Large-Scale-Dynamic-Data encompasses the next wave of Big Data, and namely dynamic data arising from ubiquitous sensing and control in engineered, natural, and societal systems, through multitudes of heterogeneous sensors and controllers instrumenting these systems, and where opportunities and challenges at these "large-scales" relate not only to data size but the heterogeneity in data, data collection modalities, fidelities, and timescales, ranging from real-time data to archival data. In tandem with this important dimension of dynamic data, there is an extended view of Big Computing, which includes the collective computing by networked assemblies of multitudes of sensors and controllers, this range from the high-end to the real-time seamlessly integrated and unified, and comprising the Large-Scale-Big-Computing. InfoSymbiotics/DDDAS engenders transformative impact in many application domains, ranging from the nano-scale to the terra-scale and to the extra-terra-scale. The talk will address opportunities for new capabilities together with corresponding research challenges, with illustrative examples from several application areas including environmental sciences, geosciences, and space sciences.

Can Regional Climate Models be used in the assessment of vulnerability and risk caused by extreme events?

NASA Astrophysics Data System (ADS)

Nunes, Ana

2015-04-01

Extreme meteorological events played an important role in catastrophic occurrences observed in the past over densely populated areas in Brazil. This motived the proposal of an integrated system for analysis and assessment of vulnerability and risk caused by extreme events in urban areas that are particularly affected by complex topography. That requires a multi-scale approach, which is centered on a regional modeling system, consisting of a regional (spectral) climate model coupled to a land-surface scheme. This regional modeling system employs a boundary forcing method based on scale-selective bias correction and assimilation of satellite-based precipitation estimates. Scale-selective bias correction is a method similar to the spectral nudging technique for dynamical downscaling that allows internal modes to develop in agreement with the large-scale features, while the precipitation assimilation procedure improves the modeled deep-convection and drives the land-surface scheme variables. Here, the scale-selective bias correction acts only on the rotational part of the wind field, letting the precipitation assimilation procedure to correct moisture convergence, in order to reconstruct South American current climate within the South American Hydroclimate Reconstruction Project. The hydroclimate reconstruction outputs might eventually produce improved initial conditions for high-resolution numerical integrations in metropolitan regions, generating more reliable short-term precipitation predictions, and providing accurate hidrometeorological variables to higher resolution geomorphological models. Better representation of deep-convection from intermediate scales is relevant when the resolution of the regional modeling system is refined by any method to meet the scale of geomorphological dynamic models of stability and mass movement, assisting in the assessment of risk areas and estimation of terrain stability over complex topography. The reconstruction of past extreme events also helps the development of a system for decision-making, regarding natural and social disasters, and reducing impacts. Numerical experiments using this regional modeling system successfully modeled severe weather events in Brazil. Comparisons with the NCEP Climate Forecast System Reanalysis outputs were made at resolutions of about 40- and 25-km of the regional climate model.

An Integrated Approach for Urban Earthquake Vulnerability Analyses

NASA Astrophysics Data System (ADS)

Düzgün, H. S.; Yücemen, M. S.; Kalaycioglu, H. S.

2009-04-01

The earthquake risk for an urban area has increased over the years due to the increasing complexities in urban environments. The main reasons are the location of major cities in hazard prone areas, growth in urbanization and population and rising wealth measures. In recent years physical examples of these factors are observed through the growing costs of major disasters in urban areas which have stimulated a demand for in-depth evaluation of possible strategies to manage the large scale damaging effects of earthquakes. Understanding and formulation of urban earthquake risk requires consideration of a wide range of risk aspects, which can be handled by developing an integrated approach. In such an integrated approach, an interdisciplinary view should be incorporated into the risk assessment. Risk assessment for an urban area requires prediction of vulnerabilities related to elements at risk in the urban area and integration of individual vulnerability assessments. However, due to complex nature of an urban environment, estimating vulnerabilities and integrating them necessities development of integrated approaches in which vulnerabilities of social, economical, structural (building stock and infrastructure), cultural and historical heritage are estimated for a given urban area over a given time period. In this study an integrated urban earthquake vulnerability assessment framework, which considers vulnerability of urban environment in a holistic manner and performs the vulnerability assessment for the smallest administrative unit, namely at neighborhood scale, is proposed. The main motivation behind this approach is the inability to implement existing vulnerability assessment methodologies for countries like Turkey, where the required data are usually missing or inadequate and decision makers seek for prioritization of their limited resources in risk reduction in the administrative districts from which they are responsible. The methodology integrates socio-economical, structural, coastal, ground condition, organizational vulnerabilities, as well as accessibility to critical services within the framework. The proposed framework has the following eight components: Seismic hazard analysis, soil response analysis, tsunami inundation analysis, structural vulnerability analysis, socio-economic vulnerability analysis, accessibility to critical services, GIS-based integrated vulnerability assessment, and visualization of vulnerabilities in 3D virtual city model The integrated model for various vulnerabilities obtained for the urban area is developed in GIS environment by using individual vulnerability assessments for considered elements at risk and serve for establishing the backbone of the spatial decision support system. The stages followed in the model are: Determination of a common mapping unit for each aspect of urban earthquake vulnerability, formation of a geo-database for the vulnerabilities, evaluation of urban vulnerability based on multi attribute utility theory with various weighting algorithms, mapping of the evaluated integrated earthquake risk in geographic information systems (GIS) in the neighborhood scale. The framework is also applicable to larger geographical mapping scales, for example, the building scale. When illustrating the results in building scale, 3-D visualizations with remote sensing data is used so that decision-makers can easily interpret the outputs. The proposed vulnerability assessment framework is flexible and can easily be applied to urban environments at various geographical scales with different mapping units. The obtained total vulnerability maps for the urban area provide a baseline for the development of risk reduction strategies for the decision makers. Moreover, as several aspects of elements at risk for an urban area is considered through vulnerability analyses, effect on changes in vulnerability conditions on the total can easily be determined. The developed approach also enables decision makers to monitor temporal and spatial changes in the urban environment due to implementation of risk reduction strategies.

Flux front penetration in disordered superconductors.

PubMed

Zapperi, S; Moreira, A A; Andrade, J S

2001-04-16

We investigate flux front penetration in a disordered type-II superconductor by molecular dynamics simulations of interacting vortices and find scaling laws for the front position and the density profile. The scaling can be understood by performing a coarse graining of the system and writing a disordered nonlinear diffusion equation. Integrating numerically the equation, we observe a crossover from flat to fractal front penetration as the system parameters are varied. The value of the fractal dimension indicates that the invasion process is described by gradient percolation.

Integrating mental health into chronic care in South Africa: the development of a district mental healthcare plan

PubMed Central

Petersen, Inge; Fairall, Lara; Bhana, Arvin; Kathree, Tasneem; Selohilwe, One; Brooke-Sumner, Carrie; Faris, Gill; Breuer, Erica; Sibanyoni, Nomvula; Lund, Crick; Patel, Vikram

2016-01-01

Background In South Africa, the escalating prevalence of chronic illness and its high comorbidity with mental disorders bring to the fore the need for integrating mental health into chronic care at district level. Aims To develop a district mental healthcare plan (MHCP) in South Africa that integrates mental healthcare for depression, alcohol use disorders and schizophrenia into chronic care. Method Mixed methods using a situation analysis, qualitative key informant interviews, theory of change workshops and piloting of the plan in one health facility informed the development of the MHCP. Results Collaborative care packages for the three conditions were developed to enable integration at the organisational, facility and community levels, supported by a human resource mix and implementation tools. Potential barriers to the feasibility of implementation at scale were identified. Conclusions The plan leverages resources and systems availed by the emerging chronic care service delivery platform for the integration of mental health. This strengthens the potential for future scale up. PMID:26447176

MEMOSys: Bioinformatics platform for genome-scale metabolic models

PubMed Central

2011-01-01

Background Recent advances in genomic sequencing have enabled the use of genome sequencing in standard biological and biotechnological research projects. The challenge is how to integrate the large amount of data in order to gain novel biological insights. One way to leverage sequence data is to use genome-scale metabolic models. We have therefore designed and implemented a bioinformatics platform which supports the development of such metabolic models. Results MEMOSys (MEtabolic MOdel research and development System) is a versatile platform for the management, storage, and development of genome-scale metabolic models. It supports the development of new models by providing a built-in version control system which offers access to the complete developmental history. Moreover, the integrated web board, the authorization system, and the definition of user roles allow collaborations across departments and institutions. Research on existing models is facilitated by a search system, references to external databases, and a feature-rich comparison mechanism. MEMOSys provides customizable data exchange mechanisms using the SBML format to enable analysis in external tools. The web application is based on the Java EE framework and offers an intuitive user interface. It currently contains six annotated microbial metabolic models. Conclusions We have developed a web-based system designed to provide researchers a novel application facilitating the management and development of metabolic models. The system is freely available at http://www.icbi.at/MEMOSys. PMID:21276275

UK Environmental Prediction - integration and evaluation at the convective scale

NASA Astrophysics Data System (ADS)

Fallmann, Joachim; Lewis, Huw; Castillo, Juan Manuel; Pearson, David; Harris, Chris; Saulter, Andy; Bricheno, Lucy; Blyth, Eleanor

2016-04-01

It has long been understood that accurate prediction and warning of the impacts of severe weather requires an integrated approach to forecasting. For example, high impact weather is typically manifested through various interactions and feedbacks between different components of the Earth System. Damaging high winds can lead to significant damage from the large waves and storm surge along coastlines. The impact of intense rainfall can be translated through saturated soils and land surface processes, high river flows and flooding inland. The substantial impacts on individuals, businesses and infrastructure of such events indicate a pressing need to understand better the value that might be delivered through more integrated environmental prediction. To address this need, the Met Office, NERC Centre for Ecology & Hydrology and NERC National Oceanography Centre have begun to develop the foundations of a coupled high resolution probabilistic forecast system for the UK at km-scale. This links together existing model components of the atmosphere, coastal ocean, land surface and hydrology. Our initial focus has been on a 2-year Prototype project to demonstrate the UK coupled prediction concept in research mode. This presentation will provide an update on UK environmental prediction activities. We will present the results from the initial implementation of an atmosphere-land-ocean coupled system and discuss progress and initial results from further development to integrate wave interactions. We will discuss future directions and opportunities for collaboration in environmental prediction, and the challenges to realise the potential of integrated regional coupled forecasting for improving predictions and applications.

Automated multiplex genome-scale engineering in yeast

PubMed Central

Si, Tong; Chao, Ran; Min, Yuhao; Wu, Yuying; Ren, Wen; Zhao, Huimin

2017-01-01

Genome-scale engineering is indispensable in understanding and engineering microorganisms, but the current tools are mainly limited to bacterial systems. Here we report an automated platform for multiplex genome-scale engineering in Saccharomyces cerevisiae, an important eukaryotic model and widely used microbial cell factory. Standardized genetic parts encoding overexpression and knockdown mutations of >90% yeast genes are created in a single step from a full-length cDNA library. With the aid of CRISPR-Cas, these genetic parts are iteratively integrated into the repetitive genomic sequences in a modular manner using robotic automation. This system allows functional mapping and multiplex optimization on a genome scale for diverse phenotypes including cellulase expression, isobutanol production, glycerol utilization and acetic acid tolerance, and may greatly accelerate future genome-scale engineering endeavours in yeast. PMID:28469255

Family impact of assistive technology scale: development of a measurement scale for parents of children with complex communication needs.

PubMed

Delarosa, Elizabeth; Horner, Stephanie; Eisenberg, Casey; Ball, Laura; Renzoni, Anne Marie; Ryan, Stephen E

2012-09-01

Young people use augmentative and alternative communication (AAC) systems to meet their everyday communication needs. However, the successful integration of an AAC system into a child's life requires strong commitment and continuous support from parents and other family members. This article describes the development and evaluation of the Family Impact of Assistive Technology Scale for AAC Systems - a parent-report questionnaire intended to detect the impact of AAC systems on the lives of children with complex communication needs and their families. The study involved 179 parents and clinical experts to test the content and face validities of the questionnaire, demonstrate its internal reliability and stability over time, and estimate its convergent construct validity when compared to a standardized measure of family impact.

Multiobjective optimization of cluster-scale urban water systems investigating alternative water sources and level of decentralization

NASA Astrophysics Data System (ADS)

Newman, J. P.; Dandy, G. C.; Maier, H. R.

2014-10-01

In many regions, conventional water supplies are unable to meet projected consumer demand. Consequently, interest has arisen in integrated urban water systems, which involve the reclamation or harvesting of alternative, localized water sources. However, this makes the planning and design of water infrastructure more difficult, as multiple objectives need to be considered, water sources need to be selected from a number of alternatives, and end uses of these sources need to be specified. In addition, the scale at which each treatment, collection, and distribution network should operate needs to be investigated. In order to deal with this complexity, a framework for planning and designing water infrastructure taking into account integrated urban water management principles is presented in this paper and applied to a rural greenfield development. Various options for water supply, and the scale at which they operate were investigated in order to determine the life-cycle trade-offs between water savings, cost, and GHG emissions as calculated from models calibrated using Australian data. The decision space includes the choice of water sources, storage tanks, treatment facilities, and pipes for water conveyance. For each water system analyzed, infrastructure components were sized using multiobjective genetic algorithms. The results indicate that local water sources are competitive in terms of cost and GHG emissions, and can reduce demand on the potable system by as much as 54%. Economies of scale in treatment dominated the diseconomies of scale in collection and distribution of water. Therefore, water systems that connect large clusters of households tend to be more cost efficient and have lower GHG emissions. In addition, water systems that recycle wastewater tended to perform better than systems that captured roof-runoff. Through these results, the framework was shown to be effective at identifying near optimal trade-offs between competing objectives, thereby enabling informed decisions to be made when planning water systems for greenfield developments.

Near Earth Asteroid Scout Solar Sail Engineering Development Unit Test Suite

NASA Technical Reports Server (NTRS)

Lockett, Tiffany Russell; Few, Alexander; Wilson, Richard

2017-01-01

The Near Earth Asteroid (NEA) Scout project is a 6U reconnaissance mission to investigate a near Earth asteroid utilizing an 86m(sub 2) solar sail as the primary propulsion system. This will be the largest solar sail NASA has launched to date. NEA Scout is currently manifested on the maiden voyage of the Space Launch System in 2018. In development of the solar sail subsystem, design challenges were identified and investigated for packaging within a 6U form factor and deployment in cis-lunar space. Analysis was able to capture understanding of thermal, stress, and dynamics of the stowed system as well as mature an integrated sail membrane model for deployed flight dynamics. Full scale system testing on the ground is the optimal way to demonstrate system robustness, repeatability, and overall performance on a compressed flight schedule. To physically test the system, the team developed a flight sized engineering development unit with design features as close to flight as possible. The test suite included ascent vent, random vibration, functional deployments, thermal vacuum, and full sail deployments. All of these tests contributed towards development of the final flight unit. This paper will address several of the design challenges and lessons learned from the NEA Scout solar sail subsystem engineering development unit. Testing on the component level all the way to the integrated subsystem level. From optical properties of the sail material to fold and spooling the single sail, the team has developed a robust deployment system for the solar sail. The team completed several deployments of the sail system in preparation for flight at half scale (4m) and full scale (6.8m): boom only, half scale sail deployment, and full scale sail deployment. This paper will also address expected and received test results from ascent vent, random vibration, and deployment tests.

The scientific data acquisition system of the GAMMA-400 space project

NASA Astrophysics Data System (ADS)

Bobkov, S. G.; Serdin, O. V.; Gorbunov, M. S.; Arkhangelskiy, A. I.; Topchiev, N. P.

2016-02-01

The description of scientific data acquisition system (SDAS) designed by SRISA for the GAMMA-400 space project is presented. We consider the problem of different level electronics unification: the set of reliable fault-tolerant integrated circuits fabricated on Silicon-on-Insulator 0.25 mkm CMOS technology and the high-speed interfaces and reliable modules used in the space instruments. The characteristics of reliable fault-tolerant very large scale integration (VLSI) technology designed by SRISA for the developing of computation systems for space applications are considered. The scalable net structure of SDAS based on Serial RapidIO interface including real-time operating system BAGET is described too.

Nuclear Energy Advanced Modeling and Simulation Waste Integrated Performance and Safety Codes (NEAMS Waste IPSC).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schultz, Peter Andrew

The objective of the U.S. Department of Energy Office of Nuclear Energy Advanced Modeling and Simulation Waste Integrated Performance and Safety Codes (NEAMS Waste IPSC) is to provide an integrated suite of computational modeling and simulation (M&S) capabilities to quantitatively assess the long-term performance of waste forms in the engineered and geologic environments of a radioactive-waste storage facility or disposal repository. Achieving the objective of modeling the performance of a disposal scenario requires describing processes involved in waste form degradation and radionuclide release at the subcontinuum scale, beginning with mechanistic descriptions of chemical reactions and chemical kinetics at the atomicmore » scale, and upscaling into effective, validated constitutive models for input to high-fidelity continuum scale codes for coupled multiphysics simulations of release and transport. Verification and validation (V&V) is required throughout the system to establish evidence-based metrics for the level of confidence in M&S codes and capabilities, including at the subcontiunuum scale and the constitutive models they inform or generate. This Report outlines the nature of the V&V challenge at the subcontinuum scale, an approach to incorporate V&V concepts into subcontinuum scale modeling and simulation (M&S), and a plan to incrementally incorporate effective V&V into subcontinuum scale M&S destined for use in the NEAMS Waste IPSC work flow to meet requirements of quantitative confidence in the constitutive models informed by subcontinuum scale phenomena.« less

Advanced Fiber-optic Monitoring System for Space-flight Applications

NASA Technical Reports Server (NTRS)

Hull, M. S.; VanTassell, R. L.; Pennington, C. D.; Roman, M.

2005-01-01

Researchers at Luna Innovations Inc. and the National Aeronautic and Space Administration s Marshall Space Flight Center (NASA MSFC) have developed an integrated fiber-optic sensor system for real-time monitoring of chemical contaminants and whole-cell bacterial pathogens in water. The system integrates interferometric and evanescent-wave optical fiber-based sensing methodologies with atomic force microscopy (AFM) and long-period grating (LPG) technology to provide versatile measurement capability for both micro- and nano-scale analytes. Sensors can be multiplexed in an array format and embedded in a totally self-contained laboratory card for use with an automated microfluidics platform.

Factorial and construct validity of the revised short form integrative psychotherapy alliance scales for family, couple, and individual therapy.

PubMed

Pinsof, William M; Zinbarg, Richard; Knobloch-Fedders, Lynne M

2008-09-01

The Integrative Psychotherapy Alliance model brought an interpersonal and systemic perspective to bear on theory, research, and practice on the psychotherapeutic alliance. Questions have been raised about the independence of the theoretical factors in the model and their operationalization in the Individual, Couple, and Family Therapy Alliance Scales. This paper presents results of a confirmatory factor analysis of the scales that delineated at least three distinct interpersonal factors as well as shorter versions of the three scales to facilitate their use in research and practice. The paper also presents the results of a study testing each factor's association with client retention and progress over the first eight sessions in individual and couple therapy. At least two of the interpersonal factors were uniquely associated with progress in individual and couple functioning. Implications of the results for theory, research, practice, and training in individual, couple, and family therapy are elaborated.

The Role of a Provider-Sponsored Health Plan in Achieving Scale and Integration.

PubMed

Johnson, Steven P

2016-01-01

In pursuit of two primary strategies-to become an integrated delivery network (IDN) on the local level and to achieve additional overall organizational scale to sustain operations-Health First, based in Rockledge, Florida, relies on the success of its provider-sponsored health plan (PSHP) as a critical asset. For Health First, the PSHP serves as an agent for holding and administering financial risk for the health of populations. In addition, we are learning that our PSHP is a critical asset in support of integrating the components of our care delivery system to manage that financial risk effectively, efficiently, and in a manner that creates a unified experience for the customer.Health First is challenged by continuing pressure on reimbursement, as well as by a substantial regulatory burden, as we work to optimize the environments and tools of care and population health management. Even with strong margins and a healthy balance sheet, we simply do not have the resources needed to bring an IDN robustly to life. However, we have discovered that our PSHP can be the vehicle that carries us to additional scale. Many health systems do not own or otherwise have access to a PSHP to hold and manage financial risk. Health First sought and found a not-for-profit health system with complementary goals and a strong brand to partner with, and we now provide private-label health plan products for that system using its strong name while operating the insurance functions under our license and with our capabilities.

XLinkDB 2.0: integrated, large-scale structural analysis of protein crosslinking data

PubMed Central

Schweppe, Devin K.; Zheng, Chunxiang; Chavez, Juan D.; Navare, Arti T.; Wu, Xia; Eng, Jimmy K.; Bruce, James E.

2016-01-01

Motivation: Large-scale chemical cross-linking with mass spectrometry (XL-MS) analyses are quickly becoming a powerful means for high-throughput determination of protein structural information and protein–protein interactions. Recent studies have garnered thousands of cross-linked interactions, yet the field lacks an effective tool to compile experimental data or access the network and structural knowledge for these large scale analyses. We present XLinkDB 2.0 which integrates tools for network analysis, Protein Databank queries, modeling of predicted protein structures and modeling of docked protein structures. The novel, integrated approach of XLinkDB 2.0 enables the holistic analysis of XL-MS protein interaction data without limitation to the cross-linker or analytical system used for the analysis. Availability and Implementation: XLinkDB 2.0 can be found here, including documentation and help: http://xlinkdb.gs.washington.edu/. Contact: jimbruce@uw.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:27153666

George E. Pake Prize Lecture: CMOS Technology Roadmap: Is Scaling Ending?

NASA Astrophysics Data System (ADS)

Chen, Tze-Chiang (T. C.)

The development of silicon technology has been based on the principle of physics and driven by the system needs. Traditionally, the system needs have been satisfied by the increase in transistor density and performance, as suggested by Moore's Law and guided by ''Dennard CMOS scaling theory''. As the silicon industry moves towards the 14nm node and beyond, three of the most important challenges facing Moore's Law and continued CMOS scaling are the growing standby power dissipation, the increasing variability in device characteristics and the ever increasing manufacturing cost. Actually, the first two factors are the embodiments of CMOS approaching atomistic and quantum-mechanical physics boundaries. Industry directions for addressing these challenges are also developing along three primary approaches: Extending silicon scaling through innovations in materials and device structure, expanding the level of integration through three-dimensional structures comprised of through-silicon-vias holes and chip stacking in order to enhance functionality and parallelism and exploring post-silicon CMOS innovation with new nano-devices based on distinctly different principles of physics, new materials and new processes such as spintronics, carbon nanotubes and nanowires. Hence, the infusion of new materials, innovative integration and novel device structures will continue to extend CMOS technology scaling for at least another decade.

Aquatic ecosystem protection and restoration: Advances in methods for assessment and evaluation

USGS Publications Warehouse

Bain, M.B.; Harig, A.L.; Loucks, D.P.; Goforth, R.R.; Mills, K.E.

2000-01-01

Many methods and criteria are available to assess aquatic ecosystems, and this review focuses on a set that demonstrates advancements from community analyses to methods spanning large spatial and temporal scales. Basic methods have been extended by incorporating taxa sensitivity to different forms of stress, adding measures linked to system function, synthesizing multiple faunal groups, integrating biological and physical attributes, spanning large spatial scales, and enabling simulations through time. These tools can be customized to meet the needs of a particular assessment and ecosystem. Two case studies are presented to show how new methods were applied at the ecosystem scale for achieving practical management goals. One case used an assessment of biotic structure to demonstrate how enhanced river flows can improve habitat conditions and restore a diverse fish fauna reflective of a healthy riverine ecosystem. In the second case, multitaxonomic integrity indicators were successful in distinguishing lake ecosystems that were disturbed, healthy, and in the process of restoration. Most methods strive to address the concept of biological integrity and assessment effectiveness often can be impeded by the lack of more specific ecosystem management objectives. Scientific and policy explorations are needed to define new ways for designating a healthy system so as to allow specification of precise quality criteria that will promote further development of ecosystem analysis tools.

Critical interactions between Global Fund-supported programmes and health systems: a case study in Papua New Guinea.

PubMed

Rudge, James W; Phuanakoonon, Suparat; Nema, K Henry; Mounier-Jack, Sandra; Coker, Richard

2010-11-01

In Papua New Guinea, investment by the Global Fund to Fight AIDS, Tuberculosis and Malaria (the Global Fund) has played an important role in scaling up the response to HIV and tuberculosis (TB). As part of a series of case studies on how Global Fund-supported programmes interact with national health systems, we assessed the nature and extent of integration of the Global Fund portfolios within the national HIV and TB programmes, the integration of the HIV and TB programmes within the general health system, and system-wide effects of Global Fund support in Papua New Guinea. The study relied on a literature review and 30 interviews with key stakeholders using the Systemic Rapid Assessment Toolkit and thematic analysis. Global Fund-supported activities were found to be largely integrated, or at least coordinated, with the national HIV and TB programmes. However, this has reinforced the vertical nature of these programmes with respect to the general health system, with parallel systems established to meet the demands of programme scale-up and the performance-based nature of Global Fund investment in the weak health system context of Papua New Guinea. The more parallel functions include monitoring and evaluation, and procurement and supply chain systems, while human resources and infrastructure for service delivery are increasingly integrated at more local levels. Positive synergies of Global Fund support include engagement of civil-society partners, and a reliable supply of high-quality drugs which may have increased patient confidence in the health system. However, the severely limited and overburdened pool of human resources has been skewed towards the three diseases, both at management and service delivery levels. There is also concern surrounding the sustainability of the disease programmes, given their dependence on donors. Increasing Global Fund attention towards health system strengthening was viewed positively, but should acknowledge that system changes are slow, difficult to measure and require long-term support.

Science of Integrated Approaches to Natural Resources Management

NASA Astrophysics Data System (ADS)

Tengberg, Anna; Valencia, Sandra

2017-04-01

To meet multiple environmental objectives, integrated programming is becoming increasingly important for the Global Environmental Facility (GEF), the financial mechanism of the multilateral environmental agreements, including the United Nations Convention to Combat Desertification (UNCCD). Integration of multiple environmental, social and economic objectives also contributes to the achievement of the Sustainable Development Goals (SDGs) in a timely and cost-effective way. However, integration is often not well defined. This paper therefore focuses on identifying key aspects of integration and assessing their implementation in natural resources management (NRM) projects. To that end, we draw on systems thinking literature, and carry out an analysis of a random sample of GEF integrated projects and in-depth case studies demonstrating lessons learned and good practices in addressing land degradation and other NRM challenges. We identify numerous challenges and opportunities of integrated approaches that need to be addressed in order to maximise the catalytic impact of the GEF during problem diagnosis, project design, implementation and governance. We highlight the need for projects to identify clearer system boundaries and main feedback mechanisms within those boundaries, in order to effectively address drivers of environmental change. We propose a theory of change for Integrated Natural Resources Management (INRM) projects, where short-term environmental and socio-economic benefits will first accrue at the local level. Implementation of improved INRM technologies and practices at the local level can be extended through spatial planning, strengthening of innovation systems, and financing and incentive mechanisms at the watershed and/or landscape/seascape level to sustain and enhance ecosystem services at larger scales and longer time spans. We conclude that the evolving scientific understanding of factors influencing social, technical and institutional innovations and transitions towards sustainable management of natural resources should be harnessed and integrated into GEF's influencing models and theory of change, and be coupled with updated approaches for learning, adaptive management and scaling up.

Feasibility study of a gamma camera for monitoring nuclear materials in the PRIDE facility

NASA Astrophysics Data System (ADS)

Jo, Woo Jin; Kim, Hyun-Il; An, Su Jung; Lee, Chae Young; Song, Han-Kyeol; Chung, Yong Hyun; Shin, Hee-Sung; Ahn, Seong-Kyu; Park, Se-Hwan

2014-05-01

The Korea Atomic Energy Research Institute (KAERI) has been developing pyroprocessing technology, in which actinides are recovered together with plutonium. There is no pure plutonium stream in the process, so it has an advantage of proliferation resistance. Tracking and monitoring of nuclear materials through the pyroprocess can significantly improve the transparency of the operation and safeguards. An inactive engineering-scale integrated pyroprocess facility, which is the PyRoprocess Integrated inactive DEmonstration (PRIDE) facility, was constructed to demonstrate engineering-scale processes and the integration of each unit process. the PRIDE facility may be a good test bed to investigate the feasibility of a nuclear material monitoring system. In this study, we designed a gamma camera system for nuclear material monitoring in the PRIDE facility by using a Monte Carlo simulation, and we validated the feasibility of this system. Two scenarios, according to locations of the gamma camera, were simulated using GATE (GEANT4 Application for Tomographic Emission) version 6. A prototype gamma camera with a diverging-slat collimator was developed, and the simulated and experimented results agreed well with each other. These results indicate that a gamma camera to monitor the nuclear material in the PRIDE facility can be developed.

An integrative architecture for general intelligence and executive function revealed by lesion mapping

PubMed Central

Colom, Roberto; Solomon, Jeffrey; Krueger, Frank; Forbes, Chad; Grafman, Jordan

2012-01-01

Although cognitive neuroscience has made remarkable progress in understanding the involvement of the prefrontal cortex in executive control, the broader functional networks that support high-level cognition and give rise to general intelligence remain to be well characterized. Here, we investigated the neural substrates of the general factor of intelligence (g) and executive function in 182 patients with focal brain damage using voxel-based lesion–symptom mapping. The Wechsler Adult Intelligence Scale and Delis–Kaplan Executive Function System were used to derive measures of g and executive function, respectively. Impaired performance on these measures was associated with damage to a distributed network of left lateralized brain areas, including regions of frontal and parietal cortex and white matter association tracts, which bind these areas into a coordinated system. The observed findings support an integrative framework for understanding the architecture of general intelligence and executive function, supporting their reliance upon a shared fronto-parietal network for the integration and control of cognitive representations and making specific recommendations for the application of the Wechsler Adult Intelligence Scale and Delis–Kaplan Executive Function System to the study of high-level cognition in health and disease. PMID:22396393

A Power Efficient Exaflop Computer Design for Global Cloud System Resolving Climate Models.

NASA Astrophysics Data System (ADS)

Wehner, M. F.; Oliker, L.; Shalf, J.

2008-12-01

Exascale computers would allow routine ensemble modeling of the global climate system at the cloud system resolving scale. Power and cost requirements of traditional architecture systems are likely to delay such capability for many years. We present an alternative route to the exascale using embedded processor technology to design a system optimized for ultra high resolution climate modeling. These power efficient processors, used in consumer electronic devices such as mobile phones, portable music players, cameras, etc., can be tailored to the specific needs of scientific computing. We project that a system capable of integrating a kilometer scale climate model a thousand times faster than real time could be designed and built in a five year time scale for US$75M with a power consumption of 3MW. This is cheaper, more power efficient and sooner than any other existing technology.

Chip-integrated optical power limiter based on an all-passive micro-ring resonator

NASA Astrophysics Data System (ADS)

Yan, Siqi; Dong, Jianji; Zheng, Aoling; Zhang, Xinliang

2014-10-01

Recent progress in silicon nanophotonics has dramatically advanced the possible realization of large-scale on-chip optical interconnects integration. Adopting photons as information carriers can break the performance bottleneck of electronic integrated circuit such as serious thermal losses and poor process rates. However, in integrated photonics circuits, few reported work can impose an upper limit of optical power therefore prevent the optical device from harm caused by high power. In this study, we experimentally demonstrate a feasible integrated scheme based on a single all-passive micro-ring resonator to realize the optical power limitation which has a similar function of current limiting circuit in electronics. Besides, we analyze the performance of optical power limiter at various signal bit rates. The results show that the proposed device can limit the signal power effectively at a bit rate up to 20 Gbit/s without deteriorating the signal. Meanwhile, this ultra-compact silicon device can be completely compatible with the electronic technology (typically complementary metal-oxide semiconductor technology), which may pave the way of very large scale integrated photonic circuits for all-optical information processors and artificial intelligence systems.

A large-scale clinical validation of an integrated monitoring system in the emergency department.

PubMed

Clifton, David A; Wong, David; Clifton, Lei; Wilson, Sarah; Way, Rob; Pullinger, Richard; Tarassenko, Lionel

2013-07-01

We consider an integrated patient monitoring system, combining electronic patient records with high-rate acquisition of patient physiological data. There remain many challenges in increasing the robustness of "e-health" applications to a level at which they are clinically useful, particularly in the use of automated algorithms used to detect and cope with artifact in data contained within the electronic patient record, and in analyzing and communicating the resultant data for reporting to clinicians. There is a consequential "plague of pilots," in which engineering prototype systems do not enter into clinical use. This paper describes an approach in which, for the first time, the Emergency Department (ED) of a major research hospital has adopted such systems for use during a large clinical trial. We describe the disadvantages of existing evaluation metrics when applied to such large trials, and propose a solution suitable for large-scale validation. We demonstrate that machine learning technologies embedded within healthcare information systems can provide clinical benefit, with the potential to improve patient outcomes in the busy environment of a major ED and other high-dependence areas of patient care.

Experiments on integral length scale control in atmospheric boundary layer wind tunnel

NASA Astrophysics Data System (ADS)

Varshney, Kapil; Poddar, Kamal

2011-11-01

Accurate predictions of turbulent characteristics in the atmospheric boundary layer (ABL) depends on understanding the effects of surface roughness on the spatial distribution of velocity, turbulence intensity, and turbulence length scales. Simulation of the ABL characteristics have been performed in a short test section length wind tunnel to determine the appropriate length scale factor for modeling, which ensures correct aeroelastic behavior of structural models for non-aerodynamic applications. The ABL characteristics have been simulated by using various configurations of passive devices such as vortex generators, air barriers, and slot in the test section floor which was extended into the contraction cone. Mean velocity and velocity fluctuations have been measured using a hot-wire anemometry system. Mean velocity, turbulence intensity, turbulence scale, and power spectral density of velocity fluctuations have been obtained from the experiments for various configuration of the passive devices. It is shown that the integral length scale factor can be controlled using various combinations of the passive devices.

Alternans Arrhythmias: From Cell to Heart

PubMed Central

Weiss, James N.; Nivala, Michael; Garfinkel, Alan; Qu, Zhilin

2010-01-01

The goal of systems biology is to relate events at the molecular level to more integrated scales from organelle to cell, tissue and living organism. Here we review how normal and abnormal excitation-contraction (EC) coupling properties emerge from the protein scale, where behaviors are dominated by randomness, to the cell and tissue scales, where heart has to beat with reliable regularity for a life-time. Beginning with the fundamental unit of EC coupling, the couplon where L-type Ca channels in the sarcolemmal membrane adjoin ryanodine receptors in the sarcoplasmic reticulum membrane, we show how a network of couplons with three basic properties (random activation, refractoriness, and recruitment) produces the classical physiological properties of excitation-contraction (EC) coupling and, under pathophysiological conditions, leads to Ca alternans and Ca waves. Moving to the tissue scale, we discuss how cellular Ca alternans and Ca waves promote both reentrant and focal arrhythmias in the heart. Throughout, we emphasize the qualitatively novel properties which emerge at each new scale of integration. PMID:21212392

Moditored unsaturated soil transport processes as a support for large scale soil and water management

NASA Astrophysics Data System (ADS)

Vanclooster, Marnik

2010-05-01

The current societal demand for sustainable soil and water management is very large. The drivers of global and climate change exert many pressures on the soil and water ecosystems, endangering appropriate ecosystem functioning. The unsaturated soil transport processes play a key role in soil-water system functioning as it controls the fluxes of water and nutrients from the soil to plants (the pedo-biosphere link), the infiltration flux of precipitated water to groundwater and the evaporative flux, and hence the feed back from the soil to the climate system. Yet, unsaturated soil transport processes are difficult to quantify since they are affected by huge variability of the governing properties at different space-time scales and the intrinsic non-linearity of the transport processes. The incompatibility of the scales between the scale at which processes reasonably can be characterized, the scale at which the theoretical process correctly can be described and the scale at which the soil and water system need to be managed, calls for further development of scaling procedures in unsaturated zone science. It also calls for a better integration of theoretical and modelling approaches to elucidate transport processes at the appropriate scales, compatible with the sustainable soil and water management objective. Moditoring science, i.e the interdisciplinary research domain where modelling and monitoring science are linked, is currently evolving significantly in the unsaturated zone hydrology area. In this presentation, a review of current moditoring strategies/techniques will be given and illustrated for solving large scale soil and water management problems. This will also allow identifying research needs in the interdisciplinary domain of modelling and monitoring and to improve the integration of unsaturated zone science in solving soil and water management issues. A focus will be given on examples of large scale soil and water management problems in Europe.

Development Of Autonomous Systems

NASA Astrophysics Data System (ADS)

Kanade, Takeo

1989-03-01

In the last several years at the Robotics Institute of Carnegie Mellon University, we have been working on two projects for developing autonomous systems: Nablab for Autonomous Land Vehicle and Ambler for Mars Rover. These two systems are for different purposes: the Navlab is a four-wheeled vehicle (van) for road and open terrain navigation, and the Ambler is a six-legged locomotor for Mars exploration. The two projects, however, share many common aspects. Both are large-scale integrated systems for navigation. In addition to the development of individual components (eg., construction and control of the vehicle, vision and perception, and planning), integration of those component technologies into a system by means of an appropriate architecture is a major issue.

Reliability Considerations of ULP Scaled CMOS in Spacecraft Systems

NASA Technical Reports Server (NTRS)

White, Mark; MacNeal, Kristen; Cooper, Mark

2012-01-01

NASA, the aerospace community, and other high reliability (hi-rel) users of advanced microelectronic products face many challenges as technology continues to scale into the deep sub-micron region. Decreasing the feature size of CMOS devices not only allows more components to be placed on a single chip, but it increases performance by allowing faster switching (or clock) speeds with reduced power compared to larger scaled devices. Higher performance, and lower operating and stand-by power characteristics of Ultra-Low Power (ULP) microelectronics are not only desirable, but also necessary to meet low power consumption design goals of critical spacecraft systems. The integration of these components in such systems, however, must be balanced with the overall risk tolerance of the project.

Joint IRIS/PASSCAL UNAVCO Seismic and GPS Installations, Testing, and Development

NASA Astrophysics Data System (ADS)

Fowler, J.; Alvarez, M.; Beaudoin, B.; Jackson, M.; Feaux, K.; Ruud, O.; Andreatta, V.; Meertens, C.; Ingate, S.

2002-12-01

Future large-scale deformation initiatives such as EarthScope (http://www.earthscope.org/) will provide an opportunity for collocation and integration of GPS receivers and broadband and short period seismic instruments. Example integration targets include PBO backbone and cluster sites with USArray Transportable (Bigfoot) and Permanent Array. A GPS seismic integration and testing facility at the IRIS/PASSCAL Instrument Center in Socorro, NM is currently performing side-by-side testing of different seismometers, GPS receivers, communications hardware, power systems and data streaming software. One configuration tested uses an integrated VSAT data communications system and a broadband seismometer collocated with a geodetic quality GPS system. Data are routed through a VSAT hub and distributed to the UNAVCO Data Archive in Boulder and the IRIS Data Management Center in Seattle. Preliminary results indicate data availability approaching 100% with a maximum latency of 5 sec.

Advanced treatment of biologically pretreated coal gasification wastewater by a novel integration of heterogeneous Fenton oxidation and biological process.

PubMed

Xu, Peng; Han, Hongjun; Zhuang, Haifeng; Hou, Baolin; Jia, Shengyong; Xu, Chunyan; Wang, Dexin

2015-04-01

Laboratorial scale experiments were conducted in order to investigate a novel system integrating heterogeneous Fenton oxidation (HFO) with anoxic moving bed biofilm reactor (ANMBBR) and biological aerated filter (BAF) process on advanced treatment of biologically pretreated coal gasification wastewater (CGW). The results indicated that HFO with the prepared catalyst (FeOx/SBAC, sewage sludge based activated carbon (SBAC) which loaded Fe oxides) played a key role in eliminating COD and COLOR as well as in improving the biodegradability of raw wastewater. The surface reaction and hydroxyl radicals (OH) oxidation were the mechanisms for FeOx/SBAC catalytic reaction. Compared with ANMBBR-BAF process, the integrated system was more effective in abating COD, BOD5, total phenols (TPs), total nitrogen (TN) and COLOR and could shorten the retention time. Therefore, the integrated system was a promising technology for engineering applications. Copyright © 2015 Elsevier Ltd. All rights reserved.

SCALE Code System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jessee, Matthew Anderson

The SCALE Code System is a widely-used modeling and simulation suite for nuclear safety analysis and design that is developed, maintained, tested, and managed by the Reactor and Nuclear Systems Division (RNSD) of Oak Ridge National Laboratory (ORNL). SCALE provides a comprehensive, verified and validated, user-friendly tool set for criticality safety, reactor and lattice physics, radiation shielding, spent fuel and radioactive source term characterization, and sensitivity and uncertainty analysis. Since 1980, regulators, licensees, and research institutions around the world have used SCALE for safety analysis and design. SCALE provides an integrated framework with dozens of computational modules including three deterministicmore » and three Monte Carlo radiation transport solvers that are selected based on the desired solution strategy. SCALE includes current nuclear data libraries and problem-dependent processing tools for continuous-energy (CE) and multigroup (MG) neutronics and coupled neutron-gamma calculations, as well as activation, depletion, and decay calculations. SCALE includes unique capabilities for automated variance reduction for shielding calculations, as well as sensitivity and uncertainty analysis. SCALE’s graphical user interfaces assist with accurate system modeling, visualization of nuclear data, and convenient access to desired results.SCALE 6.2 provides many new capabilities and significant improvements of existing features.New capabilities include:• ENDF/B-VII.1 nuclear data libraries CE and MG with enhanced group structures,• Neutron covariance data based on ENDF/B-VII.1 and supplemented with ORNL data,• Covariance data for fission product yields and decay constants,• Stochastic uncertainty and correlation quantification for any SCALE sequence with Sampler,• Parallel calculations with KENO,• Problem-dependent temperature corrections for CE calculations,• CE shielding and criticality accident alarm system analysis with MAVRIC,• CE depletion with TRITON (T5-DEPL/T6-DEPL),• CE sensitivity/uncertainty analysis with TSUNAMI-3D,• Simplified and efficient LWR lattice physics with Polaris,• Large scale detailed spent fuel characterization with ORIGAMI and ORIGAMI Automator,• Advanced fission source convergence acceleration capabilities with Sourcerer,• Nuclear data library generation with AMPX, and• Integrated user interface with Fulcrum.Enhanced capabilities include:• Accurate and efficient CE Monte Carlo methods for eigenvalue and fixed source calculations,• Improved MG resonance self-shielding methodologies and data,• Resonance self-shielding with modernized and efficient XSProc integrated into most sequences,• Accelerated calculations with TRITON/NEWT (generally 4x faster than SCALE 6.1),• Spent fuel characterization with 1470 new reactor-specific libraries for ORIGEN,• Modernization of ORIGEN (Chebyshev Rational Approximation Method [CRAM] solver, API for high-performance depletion, new keyword input format)• Extension of the maximum mixture number to values well beyond the previous limit of 2147 to ~2 billion,• Nuclear data formats enabling the use of more than 999 energy groups,• Updated standard composition library to provide more accurate use of natural abundances, andvi• Numerous other enhancements for improved usability and stability.« less

Defense Logistics Agency Disposition Services Afghanistan Disposal Process Needed Improvement

DTIC Science & Technology

2013-11-08

audit, and management was proactive in correcting the deficiencies we identified. DLA DS eliminated backlogs, identified and corrected system ...problems, provided additional system training, corrected coding errors, added personnel to key positions, addressed scale issues, submitted debit...Service Automated Information System to the Reutilization Business Integration2 (RBI) solution. The implementation of RBI in Afghanistan occurred in

Spectral analysis of temporal non-stationary rainfall-runoff processes

NASA Astrophysics Data System (ADS)

Chang, Ching-Min; Yeh, Hund-Der

2018-04-01

This study treats the catchment as a block box system with considering the rainfall input and runoff output being a stochastic process. The temporal rainfall-runoff relationship at the catchment scale is described by a convolution integral on a continuous time scale. Using the Fourier-Stieltjes representation approach, a frequency domain solution to the convolution integral is developed to the spectral analysis of runoff processes generated by temporal non-stationary rainfall events. It is shown that the characteristic time scale of rainfall process increases the runoff discharge variability, while the catchment mean travel time constant plays the role in reducing the variability of runoff discharge. Similar to the behavior of groundwater aquifers, catchments act as a low-pass filter in the frequency domain for the rainfall input signal.

Our changing planet: The FY 1993 US global change research program. A supplement to the US President's fiscal year 1993 budget

NASA Technical Reports Server (NTRS)

1992-01-01

An improved predictive understanding of the integrated Earth system, including human interactions, will provide direct benefits by anticipating and planning for possible impacts on commerce, agriculture, energy, resource utilization, human safety, and environmental quality. The central goal of the U.S. Global Change Research Program (USGCRP) is to help establish the scientific understanding and the basis for national and international policymaking related to natural and human-induced changes in the global Earth system. This will be accomplished through: (1) establishing an integrated, comprehensive, long-term program of documenting the Earth system on a global scale; (2) conducting a program of focused studies to improve our understanding of the physical, geological, chemical, biological, and social processes that influence the Earth system processes; and (3) developing integrated conceptual and predictive Earth system models.

Graphene-Si heterogeneous nanotechnology

NASA Astrophysics Data System (ADS)

Akinwande, Deji; Tao, Li

2013-05-01

It is widely envisioned that graphene, an atomic sheet of carbon that has generated very broad interest has the largest prospects for flexible smart systems and for integrated graphene-silicon (G-Si) heterogeneous very large-scale integrated (VLSI) nanoelectronics. In this work, we focus on the latter and elucidate the research progress that has been achieved for integration of graphene with Si-CMOS including: wafer-scale graphene growth by chemical vapor deposition on Cu/SiO2/Si substrates, wafer-scale graphene transfer that afforded the fabrication of over 10,000 devices, wafer-scalable mitigation strategies to restore graphene's device characteristics via fluoropolymer interaction, and demonstrations of graphene integrated with commercial Si- CMOS chips for hybrid nanoelectronics and sensors. Metrology at the wafer-scale has led to the development of custom Raman processing software (GRISP) now available on the nanohub portal. The metrology reveals that graphene grown on 4-in substrates have monolayer quality comparable to exfoliated flakes. At room temperature, the high-performance passivated graphene devices on SiO2/Si can afford average mobilities 3000cm2/V-s and gate modulation that exceeds an order of magnitude. The latest growth research has yielded graphene with high mobilities greater than 10,000cm2/V-s on oxidized silicon. Further progress requires track compatible graphene-Si integration via wafer bonding in order to translate graphene research from basic to applied research in commercial R and D laboratories to ultimately yield a viable nanotechnology.

Villacidro solar demo plant: Integration of small-scale CSP and biogas power plants in an industrial microgrid

NASA Astrophysics Data System (ADS)

Camerada, M.; Cau, G.; Cocco, D.; Damiano, A.; Demontis, V.; Melis, T.; Musio, M.

2016-05-01

The integration of small scale concentrating solar power (CSP) in an industrial district, in order to develop a microgrid fully supplied by renewable energy sources, is presented in this paper. The plant aims to assess in real operating conditions, the performance, the effectiveness and the reliability of small-scale concentrating solar power technologies in the field of distributed generation. In particular, the potentiality of small scale CSP with thermal storage to supply dispatchable electricity to an industrial microgrid will be investigated. The microgrid will be realized in the municipal waste treatment plant of the Industrial Consortium of Villacidro, in southern Sardinia (Italy), which already includes a biogas power plant. In order to achieve the microgrid instantaneous energy balance, the analysis of the time evolution of the waste treatment plant demand and of the generation in the existing power systems has been carried out. This has allowed the design of a suitable CSP plant with thermal storage and an electrochemical storage system for supporting the proposed microgrid. At the aim of obtaining the expected energy autonomy, a specific Energy Management Strategy, which takes into account the different dynamic performances and characteristics of the demand and the generation, has been designed. In this paper, the configuration of the proposed small scale concentrating solar power (CSP) and of its thermal energy storage, based on thermocline principle, is initially described. Finally, a simulation study of the entire power system, imposing scheduled profiles based on weather forecasts, is presented.

Module-based multiscale simulation of angiogenesis in skeletal muscle

PubMed Central

2011-01-01

Background Mathematical modeling of angiogenesis has been gaining momentum as a means to shed new light on the biological complexity underlying blood vessel growth. A variety of computational models have been developed, each focusing on different aspects of the angiogenesis process and occurring at different biological scales, ranging from the molecular to the tissue levels. Integration of models at different scales is a challenging and currently unsolved problem. Results We present an object-oriented module-based computational integration strategy to build a multiscale model of angiogenesis that links currently available models. As an example case, we use this approach to integrate modules representing microvascular blood flow, oxygen transport, vascular endothelial growth factor transport and endothelial cell behavior (sensing, migration and proliferation). Modeling methodologies in these modules include algebraic equations, partial differential equations and agent-based models with complex logical rules. We apply this integrated model to simulate exercise-induced angiogenesis in skeletal muscle. The simulation results compare capillary growth patterns between different exercise conditions for a single bout of exercise. Results demonstrate how the computational infrastructure can effectively integrate multiple modules by coordinating their connectivity and data exchange. Model parameterization offers simulation flexibility and a platform for performing sensitivity analysis. Conclusions This systems biology strategy can be applied to larger scale integration of computational models of angiogenesis in skeletal muscle, or other complex processes in other tissues under physiological and pathological conditions. PMID:21463529

Sequencing Data Discovery and Integration for Earth System Science with MetaSeek

NASA Astrophysics Data System (ADS)

Hoarfrost, A.; Brown, N.; Arnosti, C.

2017-12-01

Microbial communities play a central role in biogeochemical cycles. Sequencing data resources from environmental sources have grown exponentially in recent years, and represent a singular opportunity to investigate microbial interactions with Earth system processes. Carrying out such meta-analyses depends on our ability to discover and curate sequencing data into large-scale integrated datasets. However, such integration efforts are currently challenging and time-consuming, with sequencing data scattered across multiple repositories and metadata that is not easily or comprehensively searchable. MetaSeek is a sequencing data discovery tool that integrates sequencing metadata from all the major data repositories, allowing the user to search and filter on datasets in a lightweight application with an intuitive, easy-to-use web-based interface. Users can save and share curated datasets, while other users can browse these data integrations or use them as a jumping off point for their own curation. Missing and/or erroneous metadata are inferred automatically where possible, and where not possible, users are prompted to contribute to the improvement of the sequencing metadata pool by correcting and amending metadata errors. Once an integrated dataset has been curated, users can follow simple instructions to download their raw data and quickly begin their investigations. In addition to the online interface, the MetaSeek database is easily queryable via an open API, further enabling users and facilitating integrations of MetaSeek with other data curation tools. This tool lowers the barriers to curation and integration of environmental sequencing data, clearing the path forward to illuminating the ecosystem-scale interactions between biological and abiotic processes.

Eco-hydrological Wireless Sensor Network and upscaling method research in the Heihe River Basin, China

NASA Astrophysics Data System (ADS)

Jin, Rui; kang, Jian

2017-04-01

Wireless Sensor Networks are recognized as one of most important near-surface components of GEOSS (Global Earth Observation System of Systems), with flourish development of low-cost, robust and integrated data loggers and sensors. A nested eco-hydrological wireless sensor network (EHWSN) was installed in the up- and middle-reaches of the Heihe River Basin, operated to obtain multi-scale observation of soil moisture, soil temperature and land surface temperature from 2012 till now. The spatial distribution of EHWSN was optimally designed based on the geo-statistical theory, with the aim to capture the spatial variations and temporal dynamics of soil moisture and soil temperature, and to produce ground truth at grid scale for validating the related remote sensing products and model simulation in the heterogeneous land surface. In terms of upscaling research, we have developed a set of method to aggregate multi-point WSN observations to grid scale ( 1km), including regression kriging estimation to utilize multi-resource remote sensing auxiliary information, block kriging with homogeneous measurement errors, and bayesian-based upscaling algorithm that utilizes MODIS-derived apparent thermal inertia. All the EHWSN observation are organized as datasets to be freely published at http://westdc.westgis.ac.cn/hiwater. EHWSN integrates distributed observation nodes to achieve an automated, intelligent and remote-controllable network that provides superior integrated, standardized and automated observation capabilities for hydrological and ecological processes research at the basin scale.

Sensing systems using chip-based spectrometers

NASA Astrophysics Data System (ADS)

Nitkowski, Arthur; Preston, Kyle J.; Sherwood-Droz, Nicolás.; Behr, Bradford B.; Bismilla, Yusuf; Cenko, Andrew T.; DesRoches, Brandon; Meade, Jeffrey T.; Munro, Elizabeth A.; Slaa, Jared; Schmidt, Bradley S.; Hajian, Arsen R.

2014-06-01

Tornado Spectral Systems has developed a new chip-based spectrometer called OCTANE, the Optical Coherence Tomography Advanced Nanophotonic Engine, built using a planar lightwave circuit with integrated waveguides fabricated on a silicon wafer. While designed for spectral domain optical coherence tomography (SD-OCT) systems, the same miniaturized technology can be applied to many other spectroscopic applications. The field of integrated optics enables the design of complex optical systems which are monolithically integrated on silicon chips. The form factors of these systems can be significantly smaller, more robust and less expensive than their equivalent free-space counterparts. Fabrication techniques and material systems developed for microelectronics have previously been adapted for integrated optics in the telecom industry, where millions of chip-based components are used to power the optical backbone of the internet. We have further adapted the photonic technology platform for spectroscopy applications, allowing unheard-of economies of scale for these types of optical devices. Instead of changing lenses and aligning systems, these devices are accurately designed programmatically and are easily customized for specific applications. Spectrometers using integrated optics have large advantages in systems where size, robustness and cost matter: field-deployable devices, UAVs, UUVs, satellites, handheld scanning and more. We will discuss the performance characteristics of our chip-based spectrometers and the type of spectral sensing applications enabled by this technology.

Integrating optical finger motion tracking with surface touch events.

PubMed

MacRitchie, Jennifer; McPherson, Andrew P

2015-01-01

This paper presents a method of integrating two contrasting sensor systems for studying human interaction with a mechanical system, using piano performance as the case study. Piano technique requires both precise small-scale motion of fingers on the key surfaces and planned large-scale movement of the hands and arms. Where studies of performance often focus on one of these scales in isolation, this paper investigates the relationship between them. Two sensor systems were installed on an acoustic grand piano: a monocular high-speed camera tracking the position of painted markers on the hands, and capacitive touch sensors attach to the key surfaces which measure the location of finger-key contacts. This paper highlights a method of fusing the data from these systems, including temporal and spatial alignment, segmentation into notes and automatic fingering annotation. Three case studies demonstrate the utility of the multi-sensor data: analysis of finger flexion or extension based on touch and camera marker location, timing analysis of finger-key contact preceding and following key presses, and characterization of individual finger movements in the transitions between successive key presses. Piano performance is the focus of this paper, but the sensor method could equally apply to other fine motor control scenarios, with applications to human-computer interaction.

Integrating optical finger motion tracking with surface touch events

PubMed Central

MacRitchie, Jennifer; McPherson, Andrew P.

2015-01-01

This paper presents a method of integrating two contrasting sensor systems for studying human interaction with a mechanical system, using piano performance as the case study. Piano technique requires both precise small-scale motion of fingers on the key surfaces and planned large-scale movement of the hands and arms. Where studies of performance often focus on one of these scales in isolation, this paper investigates the relationship between them. Two sensor systems were installed on an acoustic grand piano: a monocular high-speed camera tracking the position of painted markers on the hands, and capacitive touch sensors attach to the key surfaces which measure the location of finger-key contacts. This paper highlights a method of fusing the data from these systems, including temporal and spatial alignment, segmentation into notes and automatic fingering annotation. Three case studies demonstrate the utility of the multi-sensor data: analysis of finger flexion or extension based on touch and camera marker location, timing analysis of finger-key contact preceding and following key presses, and characterization of individual finger movements in the transitions between successive key presses. Piano performance is the focus of this paper, but the sensor method could equally apply to other fine motor control scenarios, with applications to human-computer interaction. PMID:26082732

Integration of micro-/nano-/quantum-scale photonic devices: scientific and technological considerations

NASA Astrophysics Data System (ADS)

Lee, El-Hang; Lee, Seung-Gol; O, Beom Hoan; Park, Se Geun

2004-08-01

Scientific and technological issues and considerations regarding the integration of miniaturized microphotonic devices, circuits and systems in micron, submicron, and quantum scale, are presented. First, we examine the issues regarding the miniaturization of photonic devices including the size effect, proximity effect, energy confinement effect, microcavity effect, optical and quantum interference effect, high field effect, nonlinear effect, noise effect, quantum optical effect, and chaotic effect. Secondly, we examine the issues regarding the interconnection including the optical alignment, minimizing the interconnection losses, and maintaining optical modes. Thirdly, we address the issues regarding the two-dimensional or three-dimensional integration either in a hybrid format or in a monolithic format between active devices and passive devices of varying functions. We find that the concept of optical printed circuit board (O-PCB) that we propose is highly attractive as a platform for micro/nano/quantum-scale photonic integration. We examine the technological issues to be addressed in the process of fabrication, characterization, and packaging for actual implementation of the miniaturization, interconnection and integration. Devices that we have used for our study include: mode conversion schemes, micro-ring and micro-racetrack resonator devices, multimode interference devices, lasers, vertical cavity surface emitting microlasers, and their arrays. Future prospects are also discussed.

High density circuit technology, part 2

NASA Technical Reports Server (NTRS)

Wade, T. E.

1982-01-01

A multilevel metal interconnection system for very large scale integration (VLSI) systems utilizing polyimides as the interlayer dielectric material is described. A complete characterization of polyimide materials is given as well as experimental methods accomplished using a double level metal test pattern. A low temperature, double exposure polyimide patterning procedure is also presented.

DEVELOP MULTI-STRESSOR, OPEN ARCHITECTURE MODELING FRAMEWORK FOR ECOLOGICAL EXPOSURE FROM SITE TO WATERSHED SCALE

EPA Science Inventory

A number of multimedia modeling frameworks are currently being developed. The Multimedia Integrated Modeling System (MIMS) is one of these frameworks. A framework should be seen as more of a multimedia modeling infrastructure than a single software system. This infrastructure do...

Theoretical approaches for dynamical ordering of biomolecular systems.

PubMed

Okumura, Hisashi; Higashi, Masahiro; Yoshida, Yuichiro; Sato, Hirofumi; Akiyama, Ryo

2018-02-01

Living systems are characterized by the dynamic assembly and disassembly of biomolecules. The dynamical ordering mechanism of these biomolecules has been investigated both experimentally and theoretically. The main theoretical approaches include quantum mechanical (QM) calculation, all-atom (AA) modeling, and coarse-grained (CG) modeling. The selected approach depends on the size of the target system (which differs among electrons, atoms, molecules, and molecular assemblies). These hierarchal approaches can be combined with molecular dynamics (MD) simulation and/or integral equation theories for liquids, which cover all size hierarchies. We review the framework of quantum mechanical/molecular mechanical (QM/MM) calculations, AA MD simulations, CG modeling, and integral equation theories. Applications of these methods to the dynamical ordering of biomolecular systems are also exemplified. The QM/MM calculation enables the study of chemical reactions. The AA MD simulation, which omits the QM calculation, can follow longer time-scale phenomena. By reducing the number of degrees of freedom and the computational cost, CG modeling can follow much longer time-scale phenomena than AA modeling. Integral equation theories for liquids elucidate the liquid structure, for example, whether the liquid follows a radial distribution function. These theoretical approaches can analyze the dynamic behaviors of biomolecular systems. They also provide useful tools for exploring the dynamic ordering systems of biomolecules, such as self-assembly. This article is part of a Special Issue entitled "Biophysical Exploration of Dynamical Ordering of Biomolecular Systems" edited by Dr. Koichi Kato. Copyright © 2017 Elsevier B.V. All rights reserved.

Imaging detectors and electronics—a view of the future

NASA Astrophysics Data System (ADS)

Spieler, Helmuth

2004-09-01

Imaging sensors and readout electronics have made tremendous strides in the past two decades. The application of modern semiconductor fabrication techniques and the introduction of customized monolithic integrated circuits have made large-scale imaging systems routine in high-energy physics. This technology is now finding its way into other areas, such as space missions, synchrotron light sources, and medical imaging. I review current developments and discuss the promise and limits of new technologies. Several detector systems are described as examples of future trends. The discussion emphasizes semiconductor detector systems, but I also include recent developments for large-scale superconducting detector arrays.

Social-ecological resilience and geomorphic systems

NASA Astrophysics Data System (ADS)

Chaffin, Brian C.; Scown, Murray

2018-03-01

Governance of coupled social-ecological systems (SESs) and the underlying geomorphic processes that structure and alter Earth's surface is a key challenge for global sustainability amid the increasing uncertainty and change that defines the Anthropocene. Social-ecological resilience as a concept of scientific inquiry has contributed to new understandings of the dynamics of change in SESs, increasing our ability to contextualize and implement governance in these systems. Often, however, the importance of geomorphic change and geomorphological knowledge is somewhat missing from processes employed to inform SES governance. In this contribution, we argue that geomorphology and social-ecological resilience research should be integrated to improve governance toward sustainability. We first provide definitions of engineering, ecological, community, and social-ecological resilience and then explore the use of these concepts within and alongside geomorphology in the literature. While ecological studies often consider geomorphology as an important factor influencing the resilience of ecosystems and geomorphological studies often consider the engineering resilience of geomorphic systems of interest, very few studies define and employ a social-ecological resilience framing and explicitly link the concept to geomorphic systems. We present five key concepts-scale, feedbacks, state or regime, thresholds and regime shifts, and humans as part of the system-which we believe can help explicitly link important aspects of social-ecological resilience inquiry and geomorphological inquiry in order to strengthen the impact of both lines of research. Finally, we discuss how these five concepts might be used to integrate social-ecological resilience and geomorphology to better understand change in, and inform governance of, SESs. To compound these dynamics of resilience, complex systems are nested and cross-scale interactions from smaller and larger scales relative to the system of interest can play formative roles during periods of collapse and reorganization. Large- and small-scale disturbances as well as large-scale system memory/capacity and small-scale innovation can have significant impacts on the trajectory of a reorganizing system (Gunderson and Holling, 2002; Chaffin and Gunderson, 2016). Attempts to measure the property of ecological resilience across complex systems amounts to attempts to measure the persistence of system-controlling variables, including processes, parameters, and important feedbacks, when the system is exposed to varying degrees of disturbance (Folke, 2016).

Nutritional Systems Biology Modeling: From Molecular Mechanisms to Physiology

PubMed Central

de Graaf, Albert A.; Freidig, Andreas P.; De Roos, Baukje; Jamshidi, Neema; Heinemann, Matthias; Rullmann, Johan A.C.; Hall, Kevin D.; Adiels, Martin; van Ommen, Ben

2009-01-01

The use of computational modeling and simulation has increased in many biological fields, but despite their potential these techniques are only marginally applied in nutritional sciences. Nevertheless, recent applications of modeling have been instrumental in answering important nutritional questions from the cellular up to the physiological levels. Capturing the complexity of today's important nutritional research questions poses a challenge for modeling to become truly integrative in the consideration and interpretation of experimental data at widely differing scales of space and time. In this review, we discuss a selection of available modeling approaches and applications relevant for nutrition. We then put these models into perspective by categorizing them according to their space and time domain. Through this categorization process, we identified a dearth of models that consider processes occurring between the microscopic and macroscopic scale. We propose a “middle-out” strategy to develop the required full-scale, multilevel computational models. Exhaustive and accurate phenotyping, the use of the virtual patient concept, and the development of biomarkers from “-omics” signatures are identified as key elements of a successful systems biology modeling approach in nutrition research—one that integrates physiological mechanisms and data at multiple space and time scales. PMID:19956660

Science based integrated approach to advanced nuclear fuel development - integrated multi-scale multi-physics hierarchical modeling and simulation framework Part III: cladding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tome, Carlos N; Caro, J A; Lebensohn, R A

2010-01-01

Advancing the performance of Light Water Reactors, Advanced Nuclear Fuel Cycles, and Advanced Reactors, such as the Next Generation Nuclear Power Plants, requires enhancing our fundamental understanding of fuel and materials behavior under irradiation. The capability to accurately model the nuclear fuel systems to develop predictive tools is critical. Not only are fabrication and performance models needed to understand specific aspects of the nuclear fuel, fully coupled fuel simulation codes are required to achieve licensing of specific nuclear fuel designs for operation. The backbone of these codes, models, and simulations is a fundamental understanding and predictive capability for simulating themore » phase and microstructural behavior of the nuclear fuel system materials and matrices. In this paper we review the current status of the advanced modeling and simulation of nuclear reactor cladding, with emphasis on what is available and what is to be developed in each scale of the project, how we propose to pass information from one scale to the next, and what experimental information is required for benchmarking and advancing the modeling at each scale level.« less

The Telecommunications and Data Acquisition Report

NASA Technical Reports Server (NTRS)

Posner, E. C. (Editor)

1989-01-01

Deep Space Network advanced systems, very large scale integration architecture for decoders, radar interface and control units, microwave time delays, microwave antenna holography, and a radio frequency interference survey are among the topics discussed.

An integrative neural model of social perception, action observation, and theory of mind.

PubMed

Yang, Daniel Y-J; Rosenblau, Gabriela; Keifer, Cara; Pelphrey, Kevin A

2015-04-01

In the field of social neuroscience, major branches of research have been instrumental in describing independent components of typical and aberrant social information processing, but the field as a whole lacks a comprehensive model that integrates different branches. We review existing research related to the neural basis of three key neural systems underlying social information processing: social perception, action observation, and theory of mind. We propose an integrative model that unites these three processes and highlights the posterior superior temporal sulcus (pSTS), which plays a central role in all three systems. Furthermore, we integrate these neural systems with the dual system account of implicit and explicit social information processing. Large-scale meta-analyses based on Neurosynth confirmed that the pSTS is at the intersection of the three neural systems. Resting-state functional connectivity analysis with 1000 subjects confirmed that the pSTS is connected to all other regions in these systems. The findings presented in this review are specifically relevant for psychiatric research especially disorders characterized by social deficits such as autism spectrum disorder. Copyright © 2015 Elsevier Ltd. All rights reserved.

Path integral Monte Carlo ground state approach: formalism, implementation, and applications

NASA Astrophysics Data System (ADS)

Yan, Yangqian; Blume, D.

2017-11-01

Monte Carlo techniques have played an important role in understanding strongly correlated systems across many areas of physics, covering a wide range of energy and length scales. Among the many Monte Carlo methods applicable to quantum mechanical systems, the path integral Monte Carlo approach with its variants has been employed widely. Since semi-classical or classical approaches will not be discussed in this review, path integral based approaches can for our purposes be divided into two categories: approaches applicable to quantum mechanical systems at zero temperature and approaches applicable to quantum mechanical systems at finite temperature. While these two approaches are related to each other, the underlying formulation and aspects of the algorithm differ. This paper reviews the path integral Monte Carlo ground state (PIGS) approach, which solves the time-independent Schrödinger equation. Specifically, the PIGS approach allows for the determination of expectation values with respect to eigen states of the few- or many-body Schrödinger equation provided the system Hamiltonian is known. The theoretical framework behind the PIGS algorithm, implementation details, and sample applications for fermionic systems are presented.

An integrative neural model of social perception, action observation, and theory of mind

PubMed Central

Yang, Daniel Y.-J.; Rosenblau, Gabriela; Keifer, Cara; Pelphrey, Kevin A.

2016-01-01

In the field of social neuroscience, major branches of research have been instrumental in describing independent components of typical and aberrant social information processing, but the field as a whole lacks a comprehensive model that integrates different branches. We review existing research related to the neural basis of three key neural systems underlying social information processing: social perception, action observation, and theory of mind. We propose an integrative model that unites these three processes and highlights the posterior superior temporal sulcus (pSTS), which plays a central role in all three systems. Furthermore, we integrate these neural systems with the dual system account of implicit and explicit social information processing. Large-scale meta-analyses based on Neurosynth confirmed that the pSTS is at the intersection of the three neural systems. Resting-state functional connectivity analysis with 1000 subjects confirmed that the pSTS is connected to all other regions in these systems. The findings presented in this review are specifically relevant for psychiatric research especially disorders characterized by social deficits such as autism spectrum disorder. PMID:25660957

Nanowire nanocomputer as a finite-state machine.

PubMed

Yao, Jun; Yan, Hao; Das, Shamik; Klemic, James F; Ellenbogen, James C; Lieber, Charles M

2014-02-18

Implementation of complex computer circuits assembled from the bottom up and integrated on the nanometer scale has long been a goal of electronics research. It requires a design and fabrication strategy that can address individual nanometer-scale electronic devices, while enabling large-scale assembly of those devices into highly organized, integrated computational circuits. We describe how such a strategy has led to the design, construction, and demonstration of a nanoelectronic finite-state machine. The system was fabricated using a design-oriented approach enabled by a deterministic, bottom-up assembly process that does not require individual nanowire registration. This methodology allowed construction of the nanoelectronic finite-state machine through modular design using a multitile architecture. Each tile/module consists of two interconnected crossbar nanowire arrays, with each cross-point consisting of a programmable nanowire transistor node. The nanoelectronic finite-state machine integrates 180 programmable nanowire transistor nodes in three tiles or six total crossbar arrays, and incorporates both sequential and arithmetic logic, with extensive intertile and intratile communication that exhibits rigorous input/output matching. Our system realizes the complete 2-bit logic flow and clocked control over state registration that are required for a finite-state machine or computer. The programmable multitile circuit was also reprogrammed to a functionally distinct 2-bit full adder with 32-set matched and complete logic output. These steps forward and the ability of our unique design-oriented deterministic methodology to yield more extensive multitile systems suggest that proposed general-purpose nanocomputers can be realized in the near future.

Nanowire nanocomputer as a finite-state machine

PubMed Central

Yao, Jun; Yan, Hao; Das, Shamik; Klemic, James F.; Ellenbogen, James C.; Lieber, Charles M.

2014-01-01

Implementation of complex computer circuits assembled from the bottom up and integrated on the nanometer scale has long been a goal of electronics research. It requires a design and fabrication strategy that can address individual nanometer-scale electronic devices, while enabling large-scale assembly of those devices into highly organized, integrated computational circuits. We describe how such a strategy has led to the design, construction, and demonstration of a nanoelectronic finite-state machine. The system was fabricated using a design-oriented approach enabled by a deterministic, bottom–up assembly process that does not require individual nanowire registration. This methodology allowed construction of the nanoelectronic finite-state machine through modular design using a multitile architecture. Each tile/module consists of two interconnected crossbar nanowire arrays, with each cross-point consisting of a programmable nanowire transistor node. The nanoelectronic finite-state machine integrates 180 programmable nanowire transistor nodes in three tiles or six total crossbar arrays, and incorporates both sequential and arithmetic logic, with extensive intertile and intratile communication that exhibits rigorous input/output matching. Our system realizes the complete 2-bit logic flow and clocked control over state registration that are required for a finite-state machine or computer. The programmable multitile circuit was also reprogrammed to a functionally distinct 2-bit full adder with 32-set matched and complete logic output. These steps forward and the ability of our unique design-oriented deterministic methodology to yield more extensive multitile systems suggest that proposed general-purpose nanocomputers can be realized in the near future. PMID:24469812

SCALE Code System 6.2.2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rearden, Bradley T.; Jessee, Matthew Anderson

The SCALE Code System is a widely used modeling and simulation suite for nuclear safety analysis and design that is developed, maintained, tested, and managed by the Reactor and Nuclear Systems Division (RNSD) of Oak Ridge National Laboratory (ORNL). SCALE provides a comprehensive, verified and validated, user-friendly tool set for criticality safety, reactor physics, radiation shielding, radioactive source term characterization, and sensitivity and uncertainty analysis. Since 1980, regulators, licensees, and research institutions around the world have used SCALE for safety analysis and design. SCALE provides an integrated framework with dozens of computational modules including 3 deterministic and 3 Monte Carlomore » radiation transport solvers that are selected based on the desired solution strategy. SCALE includes current nuclear data libraries and problem-dependent processing tools for continuous-energy (CE) and multigroup (MG) neutronics and coupled neutron-gamma calculations, as well as activation, depletion, and decay calculations. SCALE includes unique capabilities for automated variance reduction for shielding calculations, as well as sensitivity and uncertainty analysis. SCALE’s graphical user interfaces assist with accurate system modeling, visualization of nuclear data, and convenient access to desired results. SCALE 6.2 represents one of the most comprehensive revisions in the history of SCALE, providing several new capabilities and significant improvements in many existing features.« less

Modular microfluidic systems using reversibly attached PDMS fluid control modules

NASA Astrophysics Data System (ADS)

Skafte-Pedersen, Peder; Sip, Christopher G.; Folch, Albert; Dufva, Martin

2013-05-01

The use of soft lithography-based poly(dimethylsiloxane) (PDMS) valve systems is the dominating approach for high-density microscale fluidic control. Integrated systems enable complex flow control and large-scale integration, but lack modularity. In contrast, modular systems are attractive alternatives to integration because they can be tailored for different applications piecewise and without redesigning every element of the system. We present a method for reversibly coupling hard materials to soft lithography defined systems through self-aligning O-ring features thereby enabling easy interfacing of complex-valve-based systems with simpler detachable units. Using this scheme, we demonstrate the seamless interfacing of a PDMS-based fluid control module with hard polymer chips. In our system, 32 self-aligning O-ring features protruding from the PDMS fluid control module form chip-to-control module interconnections which are sealed by tightening four screws. The interconnection method is robust and supports complex fluidic operations in the reversibly attached passive chip. In addition, we developed a double-sided molding method for fabricating PDMS devices with integrated through-holes. The versatile system facilitates a wide range of applications due to the modular approach, where application specific passive chips can be readily attached to the flow control module.

Large Scale Software Building with CMake in ATLAS

NASA Astrophysics Data System (ADS)

Elmsheuser, J.; Krasznahorkay, A.; Obreshkov, E.; Undrus, A.; ATLAS Collaboration

2017-10-01

The offline software of the ATLAS experiment at the Large Hadron Collider (LHC) serves as the platform for detector data reconstruction, simulation and analysis. It is also used in the detector’s trigger system to select LHC collision events during data taking. The ATLAS offline software consists of several million lines of C++ and Python code organized in a modular design of more than 2000 specialized packages. Because of different workflows, many stable numbered releases are in parallel production use. To accommodate specific workflow requests, software patches with modified libraries are distributed on top of existing software releases on a daily basis. The different ATLAS software applications also require a flexible build system that strongly supports unit and integration tests. Within the last year this build system was migrated to CMake. A CMake configuration has been developed that allows one to easily set up and build the above mentioned software packages. This also makes it possible to develop and test new and modified packages on top of existing releases. The system also allows one to detect and execute partial rebuilds of the release based on single package changes. The build system makes use of CPack for building RPM packages out of the software releases, and CTest for running unit and integration tests. We report on the migration and integration of the ATLAS software to CMake and show working examples of this large scale project in production.

Nanowire active-matrix circuitry for low-voltage macroscale artificial skin.

PubMed

Takei, Kuniharu; Takahashi, Toshitake; Ho, Johnny C; Ko, Hyunhyub; Gillies, Andrew G; Leu, Paul W; Fearing, Ronald S; Javey, Ali

2010-10-01

Large-scale integration of high-performance electronic components on mechanically flexible substrates may enable new applications in electronics, sensing and energy. Over the past several years, tremendous progress in the printing and transfer of single-crystalline, inorganic micro- and nanostructures on plastic substrates has been achieved through various process schemes. For instance, contact printing of parallel arrays of semiconductor nanowires (NWs) has been explored as a versatile route to enable fabrication of high-performance, bendable transistors and sensors. However, truly macroscale integration of ordered NW circuitry has not yet been demonstrated, with the largest-scale active systems being of the order of 1 cm(2) (refs 11,15). This limitation is in part due to assembly- and processing-related obstacles, although larger-scale integration has been demonstrated for randomly oriented NWs (ref. 16). Driven by this challenge, here we demonstrate macroscale (7×7 cm(2)) integration of parallel NW arrays as the active-matrix backplane of a flexible pressure-sensor array (18×19 pixels). The integrated sensor array effectively functions as an artificial electronic skin, capable of monitoring applied pressure profiles with high spatial resolution. The active-matrix circuitry operates at a low operating voltage of less than 5 V and exhibits superb mechanical robustness and reliability, without performance degradation on bending to small radii of curvature (2.5 mm) for over 2,000 bending cycles. This work presents the largest integration of ordered NW-array active components, and demonstrates a model platform for future integration of nanomaterials for practical applications.

A framework for exploring integrated learning systems for the governance and management of public protected areas.

PubMed

Nkhata, Bimo Abraham; Breen, Charles

2010-02-01

This article discusses how the concept of integrated learning systems provides a useful means of exploring the functional linkages between the governance and management of public protected areas. It presents a conceptual framework of an integrated learning system that explicitly incorporates learning processes in governance and management subsystems. The framework is premised on the assumption that an understanding of an integrated learning system is essential if we are to successfully promote learning across multiple scales as a fundamental component of adaptability in the governance and management of protected areas. The framework is used to illustrate real-world situations that reflect the nature and substance of the linkages between governance and management. Drawing on lessons from North America and Africa, the article demonstrates that the establishment and maintenance of an integrated learning system take place in a complex context which links elements of governance learning and management learning subsystems. The degree to which the two subsystems are coupled influences the performance of an integrated learning system and ultimately adaptability. Such performance is largely determined by how integrated learning processes allow for the systematic testing of societal assumptions (beliefs, values, and public interest) to enable society and protected area agencies to adapt and learn in the face of social and ecological change. It is argued that an integrated perspective provides a potentially useful framework for explaining and improving shared understanding around which the concept of adaptability is structured and implemented.

Leveraging Public-Private Partnerships for the U.S. Integrated Ocean Observing System (ioos)

NASA Astrophysics Data System (ADS)

Dean, H.

2015-12-01

Today, the U.S. Government conducts the majority of ocean observations in the United States (U.S.) and across the globe. However, uncertain federal funding levels across agencies presents significant challenges for expanding or even sustaining a U.S. Integrated Ocean Observing System (IOOS). Increasingly efforts will require innovative mechanisms involving multiple actors and opportunities for industry engagement, capital investment, and international cooperation to strengthen the capacity for broadscale ocean observations. The passage of the Integrated Coastal and Ocean Observation System (ICOOS) Act in 2009 established a centralized office for systematic approaches to ocean observing and observing data integration. However, ocean observing systems at the regional and national scales have been chronically underfunded relative to the blueprint established to fulfill the goals. This poster explores the role of Public-Private Partnerships (P3s) as a means of multiplying government and private funds and capabilities to develop projects that enable revenue generation while also meeting critical ocean research and operational objectives.

Integration of medical imaging into a multi-institutional hospital information system structure.

PubMed

Dayhoff, R E

1995-01-01

The Department of Veterans Affairs (VA) is providing integrated text and image data to its clinical users at its Washington and Baltimore medical centers and, soon, at nine other medical centers. The DHCP Imaging System records clinically significant diagnostic images selected by medical specialists in a variety of departments, including cardiology, gastroenterology, pathology, dermatology, surgery, radiology, podiatry, dentistry, and emergency medicine. These images, which include color and gray scale images, and electrocardiogram waveforms, are displayed on workstations located throughout the medical centers. Integration of clinical images with the VA's electronic mail system allows transfer of data from one medical center to another. The ability to incorporate transmitted text and image data into on-line patient records at the collaborating sites is an important aspect of professional consultation. In order to achieve the maximum benefits from an integrated patient record system, a critical mass of information must be available for clinicians. When there is also seamless support for administration, it becomes possible to re-engineer the processes involved in providing medical care.

The Anthropocene: A Planetary Perspective

NASA Astrophysics Data System (ADS)

Anbar, A. D.; Hartnett, H. E.; York, A.; Selin, C.

2016-12-01

The Anthropocene is a new planetary epoch defined by the emergence of human activity as one of the most important driving forces on Earth, rivaling and also stressing the other systems that govern the planet's habitability. Public discussions and debates about the challenges of this epoch tend to be polarized. One extreme denies that humans have a planetary-scale impact, while the other wishes that this impact could disappear. The tension between these perspectives is often paralyzing. Effective adaptation and mitigation requires a new perspective that reframes the conversation. We propose a planetary perspective according to which this epoch is the result of a recent major innovation in the 4 ­billion ­year history of life on Earth: the emergence of an energy-intensive planetary civilization. The rate of human energy use is already within an order of magnitude of that of the rest of the biosphere, and rising rapidly, and so this innovation is second only to the evolution of photosynthesis in terms of energy capture and utilization by living systems. Such energy use has and will continue to affect Earth at planetary scale. This reality cannot be denied nor wished away. From this pragmatic perspective, the Anthropocene is not an unnatural event that can be reversed, as though humanity is separate from the Earth systems with which we are co-evolving. Rather, it is an evolutionary transition to be managed. This is the challenge of turning a carelessly altered planet into a carefully designed and managed world, maintaining a "safe operating space" for human civilization (Steffen et al., 2011). To do so, we need an integrated approach to Earth systems science that considers humans as a natural and integral component of Earth's systems. Insights drawn from the humanities and the social sciences must be integrated with the natural sciences in order to thrive in this new epoch. This type of integrated perspective is relatively uncontroversial on personal, local, and even regional scales. It is, however, intimidating at the global scale, for good reason: it is a daunting challenge that we barely understand and for which we are poorly prepared. In this presentation, we will address approaches to adaptation and mitigation that illustrate the promise - and pitfalls - of a planetary design perspective relevant to food, energy, water, and climate.

Establishment of a National Wind Energy Center at University of Houston

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Su Su

The DOE-supported project objectives are to: establish a national wind energy center (NWEC) at University of Houston and conduct research to address critical science and engineering issues for the development of future large MW-scale wind energy production systems, especially offshore wind turbines. The goals of the project are to: (1) establish a sound scientific/technical knowledge base of solutions to critical science and engineering issues for developing future MW-scale large wind energy production systems, (2) develop a state-of-the-art wind rotor blade research facility at the University of Houston, and (3) through multi-disciplinary research, introducing technology innovations on advanced wind-turbine materials, processing/manufacturingmore » technology, design and simulation, testing and reliability assessment methods related to future wind turbine systems for cost-effective production of offshore wind energy. To achieve the goals of the project, the following technical tasks were planned and executed during the period from April 15, 2010 to October 31, 2014 at the University of Houston: (1) Basic research on large offshore wind turbine systems (2) Applied research on innovative wind turbine rotors for large offshore wind energy systems (3) Integration of offshore wind-turbine design, advanced materials and manufacturing technologies (4) Integrity and reliability of large offshore wind turbine blades and scaled model testing (5) Education and training of graduate and undergraduate students and post- doctoral researchers (6) Development of a national offshore wind turbine blade research facility The research program addresses both basic science and engineering of current and future large wind turbine systems, especially offshore wind turbines, for MW-scale power generation. The results of the research advance current understanding of many important scientific issues and provide technical information for solving future large wind turbines with advanced design, composite materials, integrated manufacturing, and structural reliability and integrity. The educational program have trained many graduate and undergraduate students and post-doctoral level researchers to learn critical science and engineering of wind energy production systems through graduate-level courses and research, and participating in various projects in center’s large multi-disciplinary research. These students and researchers are now employed by the wind industry, national labs and universities to support the US and international wind energy industry. The national offshore wind turbine blade research facility developed in the project has been used to support the technical and training tasks planned in the program to accomplish their goals, and it is a national asset which is available for used by domestic and international researchers in the wind energy arena.« less

Chemistry integrated circuit: chemical system on a complementary metal oxide semiconductor integrated circuit.

PubMed

Nakazato, Kazuo

2014-03-28

By integrating chemical reactions on a large-scale integration (LSI) chip, new types of device can be created. For biomedical applications, monolithically integrated sensor arrays for potentiometric, amperometric and impedimetric sensing of biomolecules have been developed. The potentiometric sensor array detects pH and redox reaction as a statistical distribution of fluctuations in time and space. For the amperometric sensor array, a microelectrode structure for measuring multiple currents at high speed has been proposed. The impedimetric sensor array is designed to measure impedance up to 10 MHz. The multimodal sensor array will enable synthetic analysis and make it possible to standardize biosensor chips. Another approach is to create new functional devices by integrating molecular systems with LSI chips, for example image sensors that incorporate biological materials with a sensor array. The quantum yield of the photoelectric conversion of photosynthesis is 100%, which is extremely difficult to achieve by artificial means. In a recently developed process, a molecular wire is plugged directly into a biological photosynthetic system to efficiently conduct electrons to a gold electrode. A single photon can be detected at room temperature using such a system combined with a molecular single-electron transistor.

Informatics Resources to Support Health Care Quality Improvement in the Veterans Health Administration

PubMed Central

Hynes, Denise M.; Perrin, Ruth A.; Rappaport, Steven; Stevens, Joanne M.; Demakis, John G.

2004-01-01

Information systems are increasingly important for measuring and improving health care quality. A number of integrated health care delivery systems use advanced information systems and integrated decision support to carry out quality assurance activities, but none as large as the Veterans Health Administration (VHA). The VHA's Quality Enhancement Research Initiative (QUERI) is a large-scale, multidisciplinary quality improvement initiative designed to ensure excellence in all areas where VHA provides health care services, including inpatient, outpatient, and long-term care settings. In this paper, we describe the role of information systems in the VHA QUERI process, highlight the major information systems critical to this quality improvement process, and discuss issues associated with the use of these systems. PMID:15187063

Integration of Multifidelity Multidisciplinary Computer Codes for Design and Analysis of Supersonic Aircraft

NASA Technical Reports Server (NTRS)

Geiselhart, Karl A.; Ozoroski, Lori P.; Fenbert, James W.; Shields, Elwood W.; Li, Wu

2011-01-01

This paper documents the development of a conceptual level integrated process for design and analysis of efficient and environmentally acceptable supersonic aircraft. To overcome the technical challenges to achieve this goal, a conceptual design capability which provides users with the ability to examine the integrated solution between all disciplines and facilitates the application of multidiscipline design, analysis, and optimization on a scale greater than previously achieved, is needed. The described capability is both an interactive design environment as well as a high powered optimization system with a unique blend of low, mixed and high-fidelity engineering tools combined together in the software integration framework, ModelCenter. The various modules are described and capabilities of the system are demonstrated. The current limitations and proposed future enhancements are also discussed.

Utility of the Community Integration Questionnaire in a sample of adults with neurological and neuropsychiatric disorders receiving prevocational training.

PubMed

Tomaszewski, Robert; Mitrushina, Maura

2015-08-03

To investigate utility of the Community Integration Questionnaire (CIQ) in a mixed sample of adults with neurological and neuropsychiatric disorders. Cross-sectional, interview-based study. Participants were community-dwelling adults with disabilities resulting from neurological and neuropsychiatric disorders (N = 54), who participated in a pre-vocational readiness and social skills training program. Psychometric properties of the Community Integration Questionnaire (CIQ) were assessed and validated against Mayo-Portland Adaptability Inventory (MPAI) and The Problem Checklist from the New York University Head Injury Family Interview (PCL). Based on the revised scoring procedures, psychometric properties of the CIQ Home Competency scale were excellent, followed by the Total score and Social Integration scale. Productive Activity scale had low content validity and a weak association with the total score. Convergent and discriminant validity of the CIQ were demonstrated by correlation patterns with MPAI scales in the expected direction. Significant relationship was found with PCL Physical/Dependency scale. Significant associations were found with sex, living status, and record of subsequent employment. The results provide support for the use of the CIQ as a measure of participation in individuals with neurological and neuropsychiatric diagnoses and resulting disabilities. Implications for Rehabilitation An important goal of rehabilitation and training programs for individuals with dysfunction of the central nervous system is to promote their participation in social, vocational, and domestic activities. The Community Integration Questionnaire (CIQ) is a brief and efficient instrument for measuring these participation domains. This study demonstrated good psychometric properties and high utility of the CIQ in a sample of 54 individuals participating in a prevocational training program.

Evaluation of integration methods for hybrid simulation of complex structural systems through collapse

NASA Astrophysics Data System (ADS)

Del Carpio R., Maikol; Hashemi, M. Javad; Mosqueda, Gilberto

2017-10-01

This study examines the performance of integration methods for hybrid simulation of large and complex structural systems in the context of structural collapse due to seismic excitations. The target application is not necessarily for real-time testing, but rather for models that involve large-scale physical sub-structures and highly nonlinear numerical models. Four case studies are presented and discussed. In the first case study, the accuracy of integration schemes including two widely used methods, namely, modified version of the implicit Newmark with fixed-number of iteration (iterative) and the operator-splitting (non-iterative) is examined through pure numerical simulations. The second case study presents the results of 10 hybrid simulations repeated with the two aforementioned integration methods considering various time steps and fixed-number of iterations for the iterative integration method. The physical sub-structure in these tests consists of a single-degree-of-freedom (SDOF) cantilever column with replaceable steel coupons that provides repeatable highlynonlinear behavior including fracture-type strength and stiffness degradations. In case study three, the implicit Newmark with fixed-number of iterations is applied for hybrid simulations of a 1:2 scale steel moment frame that includes a relatively complex nonlinear numerical substructure. Lastly, a more complex numerical substructure is considered by constructing a nonlinear computational model of a moment frame coupled to a hybrid model of a 1:2 scale steel gravity frame. The last two case studies are conducted on the same porotype structure and the selection of time steps and fixed number of iterations are closely examined in pre-test simulations. The generated unbalance forces is used as an index to track the equilibrium error and predict the accuracy and stability of the simulations.

A Large-Scale Design Integration Approach Developed in Conjunction with the Ares Launch Vehicle Program

NASA Technical Reports Server (NTRS)

Redmon, John W.; Shirley, Michael C.; Kinard, Paul S.

2012-01-01

This paper presents a method for performing large-scale design integration, taking a classical 2D drawing envelope and interface approach and applying it to modern three dimensional computer aided design (3D CAD) systems. Today, the paradigm often used when performing design integration with 3D models involves a digital mockup of an overall vehicle, in the form of a massive, fully detailed, CAD assembly; therefore, adding unnecessary burden and overhead to design and product data management processes. While fully detailed data may yield a broad depth of design detail, pertinent integration features are often obscured under the excessive amounts of information, making them difficult to discern. In contrast, the envelope and interface method results in a reduction in both the amount and complexity of information necessary for design integration while yielding significant savings in time and effort when applied to today's complex design integration projects. This approach, combining classical and modern methods, proved advantageous during the complex design integration activities of the Ares I vehicle. Downstream processes, benefiting from this approach by reducing development and design cycle time, include: Creation of analysis models for the Aerodynamic discipline; Vehicle to ground interface development; Documentation development for the vehicle assembly.

Commercial-scale biotherapeutics manufacturing facility for plant-made pharmaceuticals.

PubMed

Holtz, Barry R; Berquist, Brian R; Bennett, Lindsay D; Kommineni, Vally J M; Munigunti, Ranjith K; White, Earl L; Wilkerson, Don C; Wong, Kah-Yat I; Ly, Lan H; Marcel, Sylvain

2015-10-01

Rapid, large-scale manufacture of medical countermeasures can be uniquely met by the plant-made-pharmaceutical platform technology. As a participant in the Defense Advanced Research Projects Agency (DARPA) Blue Angel project, the Caliber Biotherapeutics facility was designed, constructed, commissioned and released a therapeutic target (H1N1 influenza subunit vaccine) in <18 months from groundbreaking. As of 2015, this facility was one of the world's largest plant-based manufacturing facilities, with the capacity to process over 3500 kg of plant biomass per week in an automated multilevel growing environment using proprietary LED lighting. The facility can commission additional plant grow rooms that are already built to double this capacity. In addition to the commercial-scale manufacturing facility, a pilot production facility was designed based on the large-scale manufacturing specifications as a way to integrate product development and technology transfer. The primary research, development and manufacturing system employs vacuum-infiltrated Nicotiana benthamiana plants grown in a fully contained, hydroponic system for transient expression of recombinant proteins. This expression platform has been linked to a downstream process system, analytical characterization, and assessment of biological activity. This integrated approach has demonstrated rapid, high-quality production of therapeutic monoclonal antibody targets, including a panel of rituximab biosimilar/biobetter molecules and antiviral antibodies against influenza and dengue fever. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

Power generation in random diode arrays

NASA Astrophysics Data System (ADS)

Shvydka, Diana; Karpov, V. G.

2005-03-01

We discuss nonlinear disordered systems, random diode arrays (RDAs), which can represent such objects as large-area photovoltaics and ion channels of biological membranes. Our numerical modeling has revealed several interesting properties of RDAs. In particular, the geometrical distribution of nonuniformities across a RDA has only a minor effect on its integral characteristics determined by RDA parameter statistics. In the meantime, the dispersion of integral characteristics vs system size exhibits a nontrivial scaling dependence. Our theoretical interpretation here remains limited and is based on the picture of eddy currents flowing through weak diodes in the RDA.

High-Performance Multi-Fuel AMTEC Power System

DTIC Science & Technology

2000-12-01

AMTEC technology has demonstrated thermal to electric conversion efficiencies and power densities which make it an attractive option for meso-scaic...power generation. This report details development of an integrated, logistics-fueled, 500 W AMTEC power supply. The development targeted 2O% AMTEC ...cylindrical multi-tube/single cell AMTEC configuration with effective management of alkali metal flow; scaling down and integrating a multi-fuel micro-combustor

Energy Systems Integration Facility (ESIF): Golden, CO - Energy Integration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sheppy, Michael; VanGeet, Otto; Pless, Shanti

2015-03-01

At NREL's Energy Systems Integration Facility (ESIF) in Golden, Colo., scientists and engineers work to overcome challenges related to how the nation generates, delivers and uses energy by modernizing the interplay between energy sources, infrastructure, and data. Test facilities include a megawatt-scale ac electric grid, photovoltaic simulators and a load bank. Additionally, a high performance computing data center (HPCDC) is dedicated to advancing renewable energy and energy efficient technologies. A key design strategy is to use waste heat from the HPCDC to heat parts of the building. The ESIF boasts an annual EUI of 168.3 kBtu/ft2. This article describes themore » building's procurement, design and first year of performance.« less

The Infobiotics Workbench: an integrated in silico modelling platform for Systems and Synthetic Biology.

PubMed

Blakes, Jonathan; Twycross, Jamie; Romero-Campero, Francisco Jose; Krasnogor, Natalio

2011-12-01

The Infobiotics Workbench is an integrated software suite incorporating model specification, simulation, parameter optimization and model checking for Systems and Synthetic Biology. A modular model specification allows for straightforward creation of large-scale models containing many compartments and reactions. Models are simulated either using stochastic simulation or numerical integration, and visualized in time and space. Model parameters and structure can be optimized with evolutionary algorithms, and model properties calculated using probabilistic model checking. Source code and binaries for Linux, Mac and Windows are available at http://www.infobiotics.org/infobiotics-workbench/; released under the GNU General Public License (GPL) version 3. Natalio.Krasnogor@nottingham.ac.uk.

BioMon: A Google Earth Based Continuous Biomass Monitoring System (Demo Paper)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vatsavai, Raju

2009-01-01

We demonstrate a Google Earth based novel visualization system for continuous monitoring of biomass at regional and global scales. This system is integrated with a back-end spatiotemporal data mining system that continuously detects changes using high temporal resolution MODIS images. In addition to the visualization, we demonstrate novel query features of the system that provides insights into the current conditions of the landscape.

Lunar materials processing system integration

NASA Astrophysics Data System (ADS)

Sherwood, Brent

1992-02-01

The theme of this paper is that governmental resources will not permit the simultaneous development of all viable lunar materials processing (LMP) candidates. Choices will inevitably be made, based on the results of system integration trade studies comparing candidates to each other for high-leverage applications. It is in the best long-term interest of the LMP community to lead the selection process itself, quickly and practically. The paper is in five parts. The first part explains what systems integration means and why the specialized field of LMP needs this activity now. The second part defines the integration context for LMP -- by outlining potential lunar base functions, their interrelationships and constraints. The third part establishes perspective for prioritizing the development of LMP methods, by estimating realistic scope, scale, and timing of lunar operations. The fourth part describes the use of one type of analytical tool for gaining understanding of system interactions: the input/output model. A simple example solved with linear algebra is used to illustrate. The fifth and closing part identifies specific steps needed to refine the current ability to study lunar base system integration. Research specialists have a crucial role to play now in providing the data upon which this refinement process must be based.

Maximizing information from space data resources: a case for expanding integration across research disciplines.

PubMed

Goswami, Nandu; Batzel, Jerry J; Clément, Gilles; Stein, T Peter; Hargens, Alan R; Sharp, M Keith; Blaber, Andrew P; Roma, Peter G; Hinghofer-Szalkay, Helmut G

2013-07-01

Regulatory systems are affected in space by exposure to weightlessness, high-energy radiation or other spaceflight-induced changes. The impact of spaceflight occurs across multiple scales and systems. Exploring such interactions and interdependencies via an integrative approach provides new opportunities for elucidating these complex responses. This paper argues the case for increased emphasis on integration, systematically archiving, and the coordination of past, present and future space and ground-based analogue experiments. We also discuss possible mechanisms for such integration across disciplines and missions. This article then introduces several discipline-specific reviews that show how such integration can be implemented. Areas explored include: adaptation of the central nervous system to space; cerebral autoregulation and weightlessness; modelling of the cardiovascular system in space exploration; human metabolic response to spaceflight; and exercise, artificial gravity, and physiologic countermeasures for spaceflight. In summary, spaceflight physiology research needs a conceptual framework that extends problem solving beyond disciplinary barriers. Administrative commitment and a high degree of cooperation among investigators are needed to further such a process. Well-designed interdisciplinary research can expand opportunities for broad interpretation of results across multiple physiological systems, which may have applications on Earth.

Lunar materials processing system integration

NASA Technical Reports Server (NTRS)

Sherwood, Brent

1992-01-01

The theme of this paper is that governmental resources will not permit the simultaneous development of all viable lunar materials processing (LMP) candidates. Choices will inevitably be made, based on the results of system integration trade studies comparing candidates to each other for high-leverage applications. It is in the best long-term interest of the LMP community to lead the selection process itself, quickly and practically. The paper is in five parts. The first part explains what systems integration means and why the specialized field of LMP needs this activity now. The second part defines the integration context for LMP -- by outlining potential lunar base functions, their interrelationships and constraints. The third part establishes perspective for prioritizing the development of LMP methods, by estimating realistic scope, scale, and timing of lunar operations. The fourth part describes the use of one type of analytical tool for gaining understanding of system interactions: the input/output model. A simple example solved with linear algebra is used to illustrate. The fifth and closing part identifies specific steps needed to refine the current ability to study lunar base system integration. Research specialists have a crucial role to play now in providing the data upon which this refinement process must be based.

Workflow management in large distributed systems

NASA Astrophysics Data System (ADS)

Legrand, I.; Newman, H.; Voicu, R.; Dobre, C.; Grigoras, C.

2011-12-01

The MonALISA (Monitoring Agents using a Large Integrated Services Architecture) framework provides a distributed service system capable of controlling and optimizing large-scale, data-intensive applications. An essential part of managing large-scale, distributed data-processing facilities is a monitoring system for computing facilities, storage, networks, and the very large number of applications running on these systems in near realtime. All this monitoring information gathered for all the subsystems is essential for developing the required higher-level services—the components that provide decision support and some degree of automated decisions—and for maintaining and optimizing workflow in large-scale distributed systems. These management and global optimization functions are performed by higher-level agent-based services. We present several applications of MonALISA's higher-level services including optimized dynamic routing, control, data-transfer scheduling, distributed job scheduling, dynamic allocation of storage resource to running jobs and automated management of remote services among a large set of grid facilities.

Multiscale Cloud System Modeling

NASA Technical Reports Server (NTRS)

Tao, Wei-Kuo; Moncrieff, Mitchell W.

2009-01-01

The central theme of this paper is to describe how cloud system resolving models (CRMs) of grid spacing approximately 1 km have been applied to various important problems in atmospheric science across a wide range of spatial and temporal scales and how these applications relate to other modeling approaches. A long-standing problem concerns the representation of organized precipitating convective cloud systems in weather and climate models. Since CRMs resolve the mesoscale to large scales of motion (i.e., 10 km to global) they explicitly address the cloud system problem. By explicitly representing organized convection, CRMs bypass restrictive assumptions associated with convective parameterization such as the scale gap between cumulus and large-scale motion. Dynamical models provide insight into the physical mechanisms involved with scale interaction and convective organization. Multiscale CRMs simulate convective cloud systems in computational domains up to global and have been applied in place of contemporary convective parameterizations in global models. Multiscale CRMs pose a new challenge for model validation, which is met in an integrated approach involving CRMs, operational prediction systems, observational measurements, and dynamical models in a new international project: the Year of Tropical Convection, which has an emphasis on organized tropical convection and its global effects.

The Performance Analysis of a Real-Time Integrated INS/GPS Vehicle Navigation System with Abnormal GPS Measurement Elimination

PubMed Central

Chiang, Kai-Wei; Duong, Thanh Trung; Liao, Jhen-Kai

2013-01-01

The integration of an Inertial Navigation System (INS) and the Global Positioning System (GPS) is common in mobile mapping and navigation applications to seamlessly determine the position, velocity, and orientation of the mobile platform. In most INS/GPS integrated architectures, the GPS is considered to be an accurate reference with which to correct for the systematic errors of the inertial sensors, which are composed of biases, scale factors and drift. However, the GPS receiver may produce abnormal pseudo-range errors mainly caused by ionospheric delay, tropospheric delay and the multipath effect. These errors degrade the overall position accuracy of an integrated system that uses conventional INS/GPS integration strategies such as loosely coupled (LC) and tightly coupled (TC) schemes. Conventional tightly coupled INS/GPS integration schemes apply the Klobuchar model and the Hopfield model to reduce pseudo-range delays caused by ionospheric delay and tropospheric delay, respectively, but do not address the multipath problem. However, the multipath effect (from reflected GPS signals) affects the position error far more significantly in a consumer-grade GPS receiver than in an expensive, geodetic-grade GPS receiver. To avoid this problem, a new integrated INS/GPS architecture is proposed. The proposed method is described and applied in a real-time integrated system with two integration strategies, namely, loosely coupled and tightly coupled schemes, respectively. To verify the effectiveness of the proposed method, field tests with various scenarios are conducted and the results are compared with a reliable reference system. PMID:23955434

Vehicle/engine integration. [orbit transfer vehicles

NASA Technical Reports Server (NTRS)

Cooper, L. P.; Vinopal, T. J.; Florence, D. E.; Michel, R. W.; Brown, J. R.; Bergeron, R. P.; Weldon, V. A.

1984-01-01

VEHICLE/ENGINE Integration Issues are explored for orbit transfer vehicles (OTV's). The impact of space basing and aeroassist on VEHICLE/ENGINE integration is discussed. The AOTV structure and thermal protection subsystem weights were scaled as the vehicle length and surface was changed. It is concluded that for increased allowable payload lengths in a ground-based system, lower length-to-diameter (L/D) is as important as higher mixture ration (MR) in the range of mid L/D ATOV's. Scenario validity, geometry constraints, throttle levels, reliability, and servicing are discussed in the context of engine design and engine/vehicle integration.

AIM: a personal view of where I have been and where we might be going.

PubMed

Rector, A

2001-08-01

My own career in medical informatics and AI in medicine has oscillated between concerns with medical records and concerns with knowledge representation with decision support as a pivotal integrating issue. It has focused on using AI to organise information and reduce 'muddle' and improve the user interfaces to produce 'useful and usable systems' to help doctors with a 'humanly impossible task'. Increasingly knowledge representation and ontologies have become the fulcrum for orchestrating re-use of information and integration of systems. Encouragingly, the dilemma between computational tractability and expressiveness is lessening, and ontologies and description logics are joining the mainstream both in AI in Medicine and in Intelligent Information Management generally. It has been shown possible to scale up ontologies to meet medical needs, and increasingly ontologies are playing a key role in meeting the requirements to scale up the complexity of clinical systems to meet the ever increasing demands brought about by new emphasis on reduction of errors, clinical accountability, and the explosion of knowledge on the Web.

Small-Scale Hybrid Rocket Test Stand & Characterization of Swirl Injectors

NASA Astrophysics Data System (ADS)

Summers, Matt H.

Derived from the necessity to increase testing capabilities of hybrid rocket motor (HRM) propulsion systems for Daedalus Astronautics at Arizona State University, a small-scale motor and test stand were designed and developed to characterize all components of the system. The motor is designed for simple integration and setup, such that both the forward-end enclosure and end cap can be easily removed for rapid integration of components during testing. Each of the components of the motor is removable allowing for a broad range of testing capabilities. While examining injectors and their potential it is thought ideal to obtain the highest regression rates and overall motor performance possible. The oxidizer and fuel are N2O and hydroxyl-terminated polybutadiene (HTPB), respectively, due to previous experience and simplicity. The injector designs, selected for the same reasons, are designed such that they vary only in the swirl angle. This system provides the platform for characterizing the effects of varying said swirl angle on HRM performance.

Integration of Biological and Physical Sciences to Advance Ecological Understanding of Aquatic Ecosystems

NASA Astrophysics Data System (ADS)

Luce, C. H.; Buffington, J. M.; Rieman, B. E.; Dunham, J. B.; McKean, J. A.; Thurow, R. F.; Gutierrez-Teira, B.; Rosenberger, A. E.

2005-05-01

Conservation and restoration of freshwater stream and river habitats are important goals for land management and natural resources research. Several examples of research have emerged showing that many species are adapted to temporary habitat disruptions, but that these adaptations are sensitive to the spatial grain and extent of disturbance as well as to its duration. When viewed from this perspective, questions of timing, spatial pattern, and relevant scales emerge as critical issues. In contrast, much regulation, management, and research remains tied to pollutant loading paradigms that are insensitive to either time or space scales. It is becoming clear that research is needed to examine questions and hypotheses about how physical processes affect ecological processes. Two overarching questions concisely frame the scientific issues: 1) How do we quantify physical watershed processes in a way that is meaningful to biological and ecological processes, and 2) how does the answer to that question vary with changing spatial and temporal scales? A joint understanding of scaling characteristics of physical process and the plasticity of aquatic species will be needed to accomplish this research; hence a strong need exists for integrative and collaborative development. Considering conservation biology problems in this fashion can lead to creative and non-obvious solutions because the integrated system has important non-linearities and feedbacks related to a biological system that has responded to substantial natural variability in the past. We propose that research beginning with ecological theories and principles followed with a structured examination of each physical process as related to the specific ecological theories is a strong approach to developing the necessary science, and such an approach may form a basis for development of scaling theories of hydrologic and geomorphic process. We illustrate the approach with several examples.

Advanced treatment of biologically pretreated coal gasification wastewater by a novel integration of catalytic ultrasound oxidation and membrane bioreactor.

PubMed

Jia, Shengyong; Han, Hongjun; Zhuang, Haifeng; Xu, Peng; Hou, Baolin

2015-01-01

Laboratorial scale experiments were conducted to investigate a novel system integrating catalytic ultrasound oxidation (CUO) with membrane bioreactor (CUO-MBR) on advanced treatment of biologically pretreated coal gasification wastewater. Results indicated that CUO with catalyst of FeOx/SBAC (sewage sludge based activated carbon (SBAC) which loaded Fe oxides) represented high efficiencies in eliminating TOC as well as improving the biodegradability. The integrated CUO-MBR system with low energy intensity and high frequency was more effective in eliminating COD, BOD5, TOC and reducing transmembrane pressure than either conventional MBR or ultrasound oxidation integrated MBR. The enhanced hydroxyl radical oxidation, facilitation of substrate diffusion and improvement of cell enzyme secretion were the mechanisms for CUO-MBR performance. Therefore, the integrated CUO-MBR was the promising technology for advanced treatment in engineering applications. Copyright © 2015 Elsevier Ltd. All rights reserved.

Large Scale Environmental Monitoring through Integration of Sensor and Mesh Networks.

PubMed

Jurdak, Raja; Nafaa, Abdelhamid; Barbirato, Alessio

2008-11-24

Monitoring outdoor environments through networks of wireless sensors has received interest for collecting physical and chemical samples at high spatial and temporal scales. A central challenge to environmental monitoring applications of sensor networks is the short communication range of the sensor nodes, which increases the complexity and cost of monitoring commodities that are located in geographically spread areas. To address this issue, we propose a new communication architecture that integrates sensor networks with medium range wireless mesh networks, and provides users with an advanced web portal for managing sensed information in an integrated manner. Our architecture adopts a holistic approach targeted at improving the user experience by optimizing the system performance for handling data that originates at the sensors, traverses the mesh network, and resides at the server for user consumption. This holistic approach enables users to set high level policies that can adapt the resolution of information collected at the sensors, set the preferred performance targets for their application, and run a wide range of queries and analysis on both real-time and historical data. All system components and processes will be described in this paper.

YF-12 cooperative airframe/propulsion control system program, volume 1

NASA Technical Reports Server (NTRS)

Anderson, D. L.; Connolly, G. F.; Mauro, F. M.; Reukauf, P. J.; Marks, R. (Editor)

1980-01-01

Several YF-12C airplane analog control systems were converted to a digital system. Included were the air data computer, autopilot, inlet control system, and autothrottle systems. This conversion was performed to allow assessment of digital technology applications to supersonic cruise aircraft. The digital system was composed of a digital computer and specialized interface unit. A large scale mathematical simulation of the airplane was used for integration testing and software checkout.

System on a Chip (SoC) Overview

NASA Technical Reports Server (NTRS)

LaBel, Kenneth A.

2010-01-01

System-on-a-chip or system on chip (SoC or SOC) refers to integrating all components of a computer or other electronic system into a single integrated circuit (chip). It may contain digital, analog, mixed-signal, and often radio-frequency functions all on a single chip substrate. Complexity drives it all: Radiation tolerance and testability are challenges for fault isolation, propagation, and validation. Bigger single silicon die than flown before and technology is scaling below 90nm (new qual methods). Packages have changed and are bigger and more difficult to inspect, test, and understand. Add in embedded passives. Material interfaces are more complex (underfills, processing). New rules for board layouts. Mechanical and thermal designs, etc.

Establishing an integrated human milk banking approach to strengthen newborn care.

PubMed

DeMarchis, A; Israel-Ballard, K; Mansen, Kimberly Amundson; Engmann, C

2017-05-01

The provision of donor human milk can significantly reduce morbidity and mortality among vulnerable infants and is recommended by the World Health Organization as the next best option when a mother's own milk is unavailable. Regulated human milk banks can meet this need, however, scale-up has been hindered by the absence of an appropriate model for resource-limited settings and a lack of policy support for human milk banks and for the operational procedures supporting them. To reduce infant mortality, human milk banking systems need to be scaled up and integrated with other components of newborn care. This article draws on current guidelines and best practices from human milk banks to offer a compilation of universal requirements that provide a foundation for an integrated model of newborn care that is appropriate for low- and high-resource settings alike.

Scalable Manufacturing of Solderable and Stretchable Physiologic Sensing Systems.

PubMed

Kim, Yun-Soung; Lu, Jesse; Shih, Benjamin; Gharibans, Armen; Zou, Zhanan; Matsuno, Kristen; Aguilera, Roman; Han, Yoonjae; Meek, Ann; Xiao, Jianliang; Tolley, Michael T; Coleman, Todd P

2017-10-01

Methods for microfabrication of solderable and stretchable sensing systems (S4s) and a scaled production of adhesive-integrated active S4s for health monitoring are presented. S4s' excellent solderability is achieved by the sputter-deposited nickel-vanadium and gold pad metal layers and copper interconnection. The donor substrate, which is modified with "PI islands" to become selectively adhesive for the S4s, allows the heterogeneous devices to be integrated with large-area adhesives for packaging. The feasibility for S4-based health monitoring is demonstrated by developing an S4 integrated with a strain gauge and an onboard optical indication circuit. Owing to S4s' compatibility with the standard printed circuit board assembly processes, a variety of commercially available surface mount chip components, such as the wafer level chip scale packages, chip resistors, and light-emitting diodes, can be reflow-soldered onto S4s without modifications, demonstrating the versatile and modular nature of S4s. Tegaderm-integrated S4 respiration sensors are tested for robustness for cyclic deformation, maximum stretchability, durability, and biocompatibility for multiday wear time. The results of the tests and demonstration of the respiration sensing indicate that the adhesive-integrated S4s can provide end users a way for unobtrusive health monitoring. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

An O(N) and parallel approach to integral problems by a kernel-independent fast multipole method: Application to polarization and magnetization of interacting particles

NASA Astrophysics Data System (ADS)

Jiang, Xikai; Li, Jiyuan; Zhao, Xujun; Qin, Jian; Karpeev, Dmitry; Hernandez-Ortiz, Juan; de Pablo, Juan J.; Heinonen, Olle

2016-08-01

Large classes of materials systems in physics and engineering are governed by magnetic and electrostatic interactions. Continuum or mesoscale descriptions of such systems can be cast in terms of integral equations, whose direct computational evaluation requires O(N2) operations, where N is the number of unknowns. Such a scaling, which arises from the many-body nature of the relevant Green's function, has precluded wide-spread adoption of integral methods for solution of large-scale scientific and engineering problems. In this work, a parallel computational approach is presented that relies on using scalable open source libraries and utilizes a kernel-independent Fast Multipole Method (FMM) to evaluate the integrals in O(N) operations, with O(N) memory cost, thereby substantially improving the scalability and efficiency of computational integral methods. We demonstrate the accuracy, efficiency, and scalability of our approach in the context of two examples. In the first, we solve a boundary value problem for a ferroelectric/ferromagnetic volume in free space. In the second, we solve an electrostatic problem involving polarizable dielectric bodies in an unbounded dielectric medium. The results from these test cases show that our proposed parallel approach, which is built on a kernel-independent FMM, can enable highly efficient and accurate simulations and allow for considerable flexibility in a broad range of applications.

An O( N) and parallel approach to integral problems by a kernel-independent fast multipole method: Application to polarization and magnetization of interacting particles

DOE PAGES

Jiang, Xikai; Li, Jiyuan; Zhao, Xujun; ...

2016-08-10

Large classes of materials systems in physics and engineering are governed by magnetic and electrostatic interactions. Continuum or mesoscale descriptions of such systems can be cast in terms of integral equations, whose direct computational evaluation requires O( N 2) operations, where N is the number of unknowns. Such a scaling, which arises from the many-body nature of the relevant Green's function, has precluded wide-spread adoption of integral methods for solution of large-scale scientific and engineering problems. In this work, a parallel computational approach is presented that relies on using scalable open source libraries and utilizes a kernel-independent Fast Multipole Methodmore » (FMM) to evaluate the integrals in O( N) operations, with O( N) memory cost, thereby substantially improving the scalability and efficiency of computational integral methods. We demonstrate the accuracy, efficiency, and scalability of our approach in the context of two examples. In the first, we solve a boundary value problem for a ferroelectric/ferromagnetic volume in free space. In the second, we solve an electrostatic problem involving polarizable dielectric bodies in an unbounded dielectric medium. Lastly, the results from these test cases show that our proposed parallel approach, which is built on a kernel-independent FMM, can enable highly efficient and accurate simulations and allow for considerable flexibility in a broad range of applications.« less

A QoS adaptive multimedia transport system: design, implementation and experiences

NASA Astrophysics Data System (ADS)

Campbell, Andrew; Coulson, Geoff

1997-03-01

The long awaited `new environment' of high speed broadband networks and multimedia applications is fast becoming a reality. However, few systems in existence today, whether they be large scale pilots or small scale test-beds in research laboratories, offer a fully integrated and flexible environment where multimedia applications can maximally exploit the quality of service (QoS) capabilities of supporting networks and end-systems. In this paper we describe the implementation of an adaptive transport system that incorporates a QoS oriented API and a range of mechanisms to assist applications in exploiting QoS and adapting to fluctuations in QoS. The system, which is an instantiation of the Lancaster QoS Architecture, is implemented in a multi ATM switch network environment with Linux based PC end systems and continuous media file servers. A performance evaluation of the system configured to support video-on-demand application scenario is presented and discussed. Emphasis is placed on novel features of the system and on their integration into a complete prototype. The most prominent novelty of our design is a `distributed QoS adaptation' scheme which allows applications to delegate to the system responsibility for augmenting and reducing the perceptual quality of video and audio flows when resource availability increases or decreases.

NREL’s Controllable Grid Interface Saves Time and Resources, Improves Reliability of Renewable Energy Technologies; NREL (National Renewable Energy Laboratory)

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

The National Renewable Energy Laboratory's (NREL) controllable grid interface (CGI) test system at the National Wind Technology Center (NWTC) is one of two user facilities at NREL capable of testing and analyzing the integration of megawatt-scale renewable energy systems. The CGI specializes in testing of multimegawatt-scale wind and photovoltaic (PV) technologies as well as energy storage devices, transformers, control and protection equipment at medium-voltage levels, allowing the determination of the grid impacts of the tested technology.

Liquid Tunable Microlenses based on MEMS techniques

PubMed Central

Zeng, Xuefeng; Jiang, Hongrui

2013-01-01

The recent rapid development in microlens technology has provided many opportunities for miniaturized optical systems, and has found a wide range of applications. Of these microlenses, tunable-focus microlenses are of special interest as their focal lengths can be tuned using micro-scale actuators integrated with the lens structure. Realization of such tunable microlens generally relies on the microelectromechanical system (MEMS) technologies. Here, we review the recent progress in tunable liquid microlenses. The underlying physics relevant to these microlenses are first discussed, followed by description of three main categories of tunable microlenses involving MEMS techniques, mechanically driven, electrically driven, and those integrated within microfluidic systems. PMID:24163480

Integrated clinical workstations for image and text data capture, display, and teleconsultation.

PubMed

Dayhoff, R; Kuzmak, P M; Kirin, G

1994-01-01

The Department of Veterans Affairs (VA) DHCP Imaging System digitally records clinically significant diagnostic images selected by medical specialists in a variety of hospital departments, including radiology, cardiology, gastroenterology, pathology, dermatology, hematology, surgery, podiatry, dental clinic, and emergency room. These images, which include true color and gray scale images, scanned documents, and electrocardiogram waveforms, are stored on network file servers and displayed on workstations located throughout a medical center. All images are managed by the VA's hospital information system (HIS), allowing integrated displays of text and image data from all medical specialties. Two VA medical centers currently have DHCP Imaging Systems installed, and other installations are underway.

Visualization and Analysis of Multi-scale Land Surface Products via Giovanni Portals

NASA Technical Reports Server (NTRS)

Shen, Suhung; Kempler, Steven J.; Gerasimov, Irina V.

2013-01-01

Large volumes of MODIS land data products at multiple spatial resolutions have been integrated into the Giovanni online analysis system to support studies on land cover and land use changes,focused on the Northern Eurasia and Monsoon Asia regions through the LCLUC program. Giovanni (Goddard Interactive Online Visualization ANd aNalysis Infrastructure) is a Web-based application developed by the NASA Goddard Earth Sciences Data and Information Services Center (GES DISC), providing a simple and intuitive way to visualize, analyze, and access Earth science remotely-sensed and modeled data.Customized Giovanni Web portals (Giovanni-NEESPI andGiovanni-MAIRS) have been created to integrate land, atmospheric,cryospheric, and societal products, enabling researchers to do quick exploration and basic analyses of land surface changes, and their relationships to climate, at global and regional scales. This presentation shows a sample Giovanni portal page, lists selected data products in the system, and illustrates potential analyses with imagesand time-series at global and regional scales, focusing on climatology and anomaly analysis. More information is available at the GES DISCMAIRS data support project portal: http:disc.sci.gsfc.nasa.govmairs.

Study on data model of large-scale urban and rural integrated cadastre

NASA Astrophysics Data System (ADS)

Peng, Liangyong; Huang, Quanyi; Gao, Dequan

2008-10-01

Urban and Rural Integrated Cadastre (URIC) has been the subject of great interests for modern cadastre management. It is highly desirable to develop a rational data model for establishing an information system of URIC. In this paper, firstly, the old cadastral management mode in China was introduced, the limitation was analyzed, and the conception of URIC and its development course in China were described. Afterwards, based on the requirements of cadastre management in developed region, the goal of URIC and two key ideas for realizing URIC were proposed. Then, conceptual management mode was studied and a data model of URIC was designed. At last, based on the raw data of land use survey with a scale of 1:1000 and urban conversional cadastral survey with a scale of 1:500 in Jiangyin city, a well-defined information system of URIC was established according to the data model and an uniform management of land use and use right and landownership in urban and rural area was successfully realized. Its feasibility and practicability was well proved.

Integrated energy system for the Asphalt Green Youth Sports and Arts Center and the Fireboat House. Report 79-2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Energy conservation and solar energy measures for two old buildings, different in scale and character, that are being recycled by the Neighborhood Committee for the Asphalt Green into a community Sports and Arts Center and an Environmental Studies Center are described. The approch taken by the Authority in developing the integrated energy system design for the larger, commercial-scale Sports and Arts Center was to incorporate energy conservation and renewable energy measures that minimize life-cycle costs. Energy costs will be reduced from about $50,000 per year (in 1979 dollars) to $15,000 per year. The Environmental Studies Center, formerly a fireboat stationmore » on the East River, is a smaller residential-scale structure. The approach in developing the renovation plan was to assess retrofit potential for cost-effective energy consrvation, solar domestic hot water, and active and passive solar space heating. Energy measures were selected which would maximize educational potential for school children and which could be replicated by the general public.« less

Integrated crop–livestock systems: Strategies to achieve synergy between agricultural production and environmental quality

USDA-ARS?s Scientific Manuscript database

A need to increase agricultural production across the world for food security appears to be at odds with the urgency to reduce agriculture’s negative environmental impacts. We suggest that a cause of this dichotomy is loss of diversity within agricultural systems at field, farm and landscape scales....

Solar Newsletter | Solar Research | NREL

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, General Electric Optimize Voltage Control for Utility-Scale PV As utilities increasingly add solar power components that may be used to integrate distributed solar PV onto distribution systems. More than 335 data Innovation Award for Grid Reliability PV Demonstration First Solar, the California Independent System

A Data Management System Integrating Web-Based Training and Randomized Trials

ERIC Educational Resources Information Center

Muroff, Jordana; Amodeo, Maryann; Larson, Mary Jo; Carey, Margaret; Loftin, Ralph D.

2011-01-01

This article describes a data management system (DMS) developed to support a large-scale randomized study of an innovative web-course that was designed to improve substance abuse counselors' knowledge and skills in applying a substance abuse treatment method (i.e., cognitive behavioral therapy; CBT). The randomized trial compared the performance…

Training Evaluation as an Integral Component of Training for Performance.

ERIC Educational Resources Information Center

Lapp, H. J., Jr.

A training evaluation system should address four major areas: reaction, learning, behavior, and results. The training evaluation system at GPU Nuclear Corporation addresses each of these areas through practical approaches such as course and program evaluation. GPU's program evaluation instrument uses a Likert-type scale to assess task development,…

Homogenization-based interval analysis for structural-acoustic problem involving periodical composites and multi-scale uncertain-but-bounded parameters.

PubMed

Chen, Ning; Yu, Dejie; Xia, Baizhan; Liu, Jian; Ma, Zhengdong

2017-04-01

This paper presents a homogenization-based interval analysis method for the prediction of coupled structural-acoustic systems involving periodical composites and multi-scale uncertain-but-bounded parameters. In the structural-acoustic system, the macro plate structure is assumed to be composed of a periodically uniform microstructure. The equivalent macro material properties of the microstructure are computed using the homogenization method. By integrating the first-order Taylor expansion interval analysis method with the homogenization-based finite element method, a homogenization-based interval finite element method (HIFEM) is developed to solve a periodical composite structural-acoustic system with multi-scale uncertain-but-bounded parameters. The corresponding formulations of the HIFEM are deduced. A subinterval technique is also introduced into the HIFEM for higher accuracy. Numerical examples of a hexahedral box and an automobile passenger compartment are given to demonstrate the efficiency of the presented method for a periodical composite structural-acoustic system with multi-scale uncertain-but-bounded parameters.

Establishment and assessment of a novel cleaner production process of corn grain fuel ethanol.

PubMed

Wang, Ke; Zhang, Jianhua; Tang, Lei; Zhang, Hongjian; Zhang, Guiying; Yang, Xizhao; Liu, Pei; Mao, Zhonggui

2013-11-01

An integrated corn ethanol-methane fermentation system was proposed to solve the problem of stillage handling, where thin stillage was treated by anaerobic digestion and then reused to make mash for the following ethanol fermentation. This system was evaluated at laboratory and pilot scale. Anaerobic digestion of thin stillage ran steadily with total chemical oxygen demand removal efficiency of 98% at laboratory scale and 97% at pilot scale. Ethanol production was not influenced by recycling anaerobic digestion effluent at laboratory and pilot scale. Compared with dried distillers' grains with solubles produced in conventional process, dried distillers' grains in the proposed system exhibited higher quality because of increased protein concentration and decreased salts concentration. Energetic assessment indicated that application of this novel process enhanced the net energy balance ratio from 1.26 (conventional process) to 1.76. In conclusion, the proposed system possessed technical advantage over the conventional process for corn fuel ethanol production. Copyright © 2013 Elsevier Ltd. All rights reserved.

Papaya drying and waste conversion system. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1982-02-12

This project, performed under United States Department of Energy Small-scale Appropriate Energy Technology Grant, involves demonstration of an integrated system using solar energy to process off-grade or reject fruit into marketable food products. The integrated system consists of three phases: (1) solar dehydration of usable fruit; (2) solar vacuum distillation of fermented wastes (peelings, rinds, skins, and seeds) to produce an ethanol fuel to use as a backup source of heat for dehydration; and (3) land reclamation by mixing stillage and compost with volcanic cinder and ash to produce on marginal land a rich soil suitable for growing more cropsmore » to dry. Although the system is not 100% complete the investigators have demonstrated that a small business can efficiently use solar energies in an integrated fashion to process waste into food, improve the quality of the land, and provide meaningful jobs in a region of very high unemployment.« less

Biosensor system-on-a-chip including CMOS-based signal processing circuits and 64 carbon nanotube-based sensors for the detection of a neurotransmitter.

PubMed

Lee, Byung Yang; Seo, Sung Min; Lee, Dong Joon; Lee, Minbaek; Lee, Joohyung; Cheon, Jun-Ho; Cho, Eunju; Lee, Hyunjoong; Chung, In-Young; Park, Young June; Kim, Suhwan; Hong, Seunghun

2010-04-07

We developed a carbon nanotube (CNT)-based biosensor system-on-a-chip (SoC) for the detection of a neurotransmitter. Here, 64 CNT-based sensors were integrated with silicon-based signal processing circuits in a single chip, which was made possible by combining several technological breakthroughs such as efficient signal processing, uniform CNT networks, and biocompatible functionalization of CNT-based sensors. The chip was utilized to detect glutamate, a neurotransmitter, where ammonia, a byproduct of the enzymatic reaction of glutamate and glutamate oxidase on CNT-based sensors, modulated the conductance signals to the CNT-based sensors. This is a major technological advancement in the integration of CNT-based sensors with microelectronics, and this chip can be readily integrated with larger scale lab-on-a-chip (LoC) systems for various applications such as LoC systems for neural networks.

Effects of real time control of sewer systems on treatment plant performance and receiving water quality.

PubMed

Frehmann, T; Niemann, A; Ustohal, P; Geiger, W F

2002-01-01

Four individual mathematical submodels simulating different subsystems of urban drainage were intercoupled to an integral model. The submodels (for surface runoff, flow in sewer system, wastewater treatment plant and receiving water) were calibrated on the basis of field data measured in an existing urban catchment investigation. Three different strategies for controlling the discharge in the sewer network were defined and implemented in the integral model. The impact of these control measures was quantified by representative immission state-parameters of the receiving water. The results reveal that the effect of a control measure may be ambivalent, depending on the referred component of a complex drainage system. Furthermore, it is demonstrated that the drainage system in the catchment investigation can be considerably optimised towards environmental protection and operation efficiency if an appropriate real time control on the integral scale is applied.

Impulse-induced optimum signal amplification in scale-free networks.

PubMed

Martínez, Pedro J; Chacón, Ricardo

2016-04-01

Optimizing information transmission across a network is an essential task for controlling and manipulating generic information-processing systems. Here, we show how topological amplification effects in scale-free networks of signaling devices are optimally enhanced when the impulse transmitted by periodic external signals (time integral over two consecutive zeros) is maximum. This is demonstrated theoretically by means of a star-like network of overdamped bistable systems subjected to generic zero-mean periodic signals and confirmed numerically by simulations of scale-free networks of such systems. Our results show that the enhancer effect of increasing values of the signal's impulse is due to a correlative increase of the energy transmitted by the periodic signals, while it is found to be resonant-like with respect to the topology-induced amplification mechanism.

Beyond bureaucracy: emerging trends in social care informatics.

PubMed

Wastell, David; White, Sue

2014-09-01

Existing information technology systems in much of UK social care have been designed to serve the interests of the bureaucracy rather than supporting professional practice or improving services to the public. The ill-starred Integrated Children's System in statutory children's services is typical. The Integrated Children's System is a system for form-filling, micro-managing professional practice through an enforced regime of standard processes and time scales. In this article, we argue against this dominant design. We provide several examples where technology has enabled alternative modes of support for professional work, based on socio-technical principles. One such system is Patchwork, which describes itself as a 'Facebook for Social Work'; its aim is to support multi-professional teams working with vulnerable families. © The Author(s) 2013.

The importance of integration and scale in the arbuscular mycorrhizal symbiosis.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, R. M.; Kling, M.; Environmental Research

The arbuscular mycorrhizal (AM) fungus contributes to system processes and functions at various hierarchical organizational levels, through their establishment of linkages and feedbacks between whole-plants and nutrient cycles. Even though these fungal mediated feedbacks and linkages involve lower-organizational level processes (e.g. photo-assimilate partitioning, interfacial assimilate uptake and transport mechanisms, intraradical versus extraradical fungal growth), they influence higher-organizational scales that affect community and ecosystem behavior (e.g. whole-plant photosynthesis, biodiversity, nutrient and carbon cycling, soil structure). Hence, incorporating AM fungi into research directed at understanding many of the diverse environmental issues confronting society will require knowledge of how these fungi respond tomore » or initiate changes in vegetation dynamics, soil fertility or both. Within the last few years, the rapid advancement in the development of analytical tools has increased the resolution by which we are able to quantify the mycorrhizal symbiosis. It is important that these tools are applied within a conceptual framework that is temporally and spatially relevant to fungus and host. Unfortunately, many of the studies being conducted on the mycorrhizal symbiosis at lower organizational scales are concerned with questions directed solely at understanding fungus or host without awareness of what the plant physiologist or ecologist needs for integrating the mycorrhizal association into larger organizational scales or process levels. We show by using the flow of C from plant-to-fungus-to-soil, that through thoughtful integration, we have the ability to bridge different organizational scales. Thus, an essential need of mycorrhizal research is not only to better integrate the various disciplines of mycorrhizal research, but also to identify those relevant links and scales needing further investigation for understanding the larger-organizational level responses.« less

Integration process of fermentation and liquid biphasic flotation for lipase separation from Burkholderia cepacia.

PubMed

Sankaran, Revathy; Show, Pau Loke; Lee, Sze Ying; Yap, Yee Jiun; Ling, Tau Chuan

2018-02-01

Liquid Biphasic Flotation (LBF) is an advanced recovery method that has been effectively applied for biomolecules extraction. The objective of this investigation is to incorporate the fermentation and extraction process of lipase from Burkholderia cepacia using flotation system. Initial study was conducted to compare the performance of bacteria growth and lipase production using flotation and shaker system. From the results obtained, bacteria shows quicker growth and high lipase yield via flotation system. Integration process for lipase separation was investigated and the result showed high efficiency reaching 92.29% and yield of 95.73%. Upscaling of the flotation system exhibited consistent result with the lab-scale which are 89.53% efficiency and 93.82% yield. The combination of upstream and downstream processes in a single system enables the acceleration of product formation, improves the product yield and facilitates downstream processing. This integration system demonstrated its potential for biomolecules fermentation and separation that possibly open new opportunities for industrial production. Copyright © 2017 Elsevier Ltd. All rights reserved.

Architectural Visualization of C/C++ Source Code for Program Comprehension

DOE Office of Scientific and Technical Information (OSTI.GOV)

Panas, T; Epperly, T W; Quinlan, D

2006-09-01

Structural and behavioral visualization of large-scale legacy systems to aid program comprehension is still a major challenge. The challenge is even greater when applications are implemented in flexible and expressive languages such as C and C++. In this paper, we consider visualization of static and dynamic aspects of large-scale scientific C/C++ applications. For our investigation, we reuse and integrate specialized analysis and visualization tools. Furthermore, we present a novel layout algorithm that permits a compressive architectural view of a large-scale software system. Our layout is unique in that it allows traditional program visualizations, i.e., graph structures, to be seen inmore » relation to the application's file structure.« less

An integrated water system model considering hydrological and biogeochemical processes at basin scale: model construction and application

NASA Astrophysics Data System (ADS)

Zhang, Y. Y.; Shao, Q. X.; Ye, A. Z.; Xing, H. T.

2014-08-01

Integrated water system modeling is a reasonable approach to provide scientific understanding and possible solutions to tackle the severe water crisis faced over the world and to promote the implementation of integrated river basin management. Such a modeling practice becomes more feasible nowadays due to better computing facilities and available data sources. In this study, the process-oriented water system model (HEXM) is developed by integrating multiple water related processes including hydrology, biogeochemistry, environment and ecology, as well as the interference of human activities. The model was tested in the Shaying River Catchment, the largest, highly regulated and heavily polluted tributary of Huai River Basin in China. The results show that: HEXM is well integrated with good performance on the key water related components in the complex catchments. The simulated daily runoff series at all the regulated and less-regulated stations matches observations, especially for the high and low flow events. The average values of correlation coefficient and coefficient of efficiency are 0.81 and 0.63, respectively. The dynamics of observed daily ammonia-nitrogen (NH4N) concentration, as an important index to assess water environmental quality in China, are well captured with average correlation coefficient of 0.66. Furthermore, the spatial patterns of nonpoint source pollutant load and grain yield are also simulated properly, and the outputs have good agreements with the statistics at city scale. Our model shows clear superior performance in both calibration and validation in comparison with the widely used SWAT model. This model is expected to give a strong reference for water system modeling in complex basins, and provide the scientific foundation for the implementation of integrated river basin management all over the world as well as the technical guide for the reasonable regulation of dams and sluices and environmental improvement in river basins.

Utility of a Two-source Energy Balance Approach for Daily Mapping of Landsat-scale Fluxes Over Irrigated Agriculture in a Desert Environment

NASA Astrophysics Data System (ADS)

Houborg, R.; McCabe, M. F.; Rosas Aguilar, J.; Anderson, M. C.; Hain, C.

2014-12-01

The Middle East and North Africa (MENA) region is an area characterized by limited fresh water resources, an often inefficient use of these, and relatively poor in-situ monitoring as a result of sparse meteorological observations. Enhanced satellite-based monitoring systems are needed for aiding local water resource and agricultural management activities in these data poor arid environments. A multi-sensor and multi-scale land-surface flux monitoring capacity is being implemented over parts of MENA in order to provide meaningful decision support at relevant spatiotemporal scales. The integrated modeling system uses the Atmosphere-Land Exchange Inverse (ALEXI) model and associated flux disaggregation scheme (DisALEXI), and the Spatial and Temporal Adaptive Reflectance Fusion Model (STARFM) in conjunction with model reanalysis data and remotely sensed data from polar orbiting (Landsat and MODIS; MODerate resolution Imaging Spectroradiometer) and geostationary (MSG; Meteosat Second Generation) satellite platforms to facilitate daily estimates of land surface fluxes down to sub-field scale (i.e. 30 m). Within this modeling system, thermal infrared satellite data provide information about the sub-surface moisture status and plant stress, obviating the need for precipitation input and error-prone soil surface characterizations. In this study, the integrated ALEXI-DisALEXI-STARFM framework is applied over an irrigated agricultural region in Saudi Arabia, and the daily estimates of Landsat scale water, energy and carbon fluxes are evaluated against available flux tower observations and other independent in-situ and satellite-based records. The study addresses the challenges associated with time-continuous sub-field scale mapping of land-surface fluxes in a harsh desert environment, and looks into the optimization of model descriptions and parameterizations and meteorological forcing and vegetation inputs for application over these regions.

Integrating visual learning within a model-based ATR system

NASA Astrophysics Data System (ADS)

Carlotto, Mark; Nebrich, Mark

2017-05-01

Automatic target recognition (ATR) systems, like human photo-interpreters, rely on a variety of visual information for detecting, classifying, and identifying manmade objects in aerial imagery. We describe the integration of a visual learning component into the Image Data Conditioner (IDC) for target/clutter and other visual classification tasks. The component is based on an implementation of a model of the visual cortex developed by Serre, Wolf, and Poggio. Visual learning in an ATR context requires the ability to recognize objects independent of location, scale, and rotation. Our method uses IDC to extract, rotate, and scale image chips at candidate target locations. A bootstrap learning method effectively extends the operation of the classifier beyond the training set and provides a measure of confidence. We show how the classifier can be used to learn other features that are difficult to compute from imagery such as target direction, and to assess the performance of the visual learning process itself.

Quantum interference in heterogeneous superconducting-photonic circuits on a silicon chip.

PubMed

Schuck, C; Guo, X; Fan, L; Ma, X; Poot, M; Tang, H X

2016-01-21

Quantum information processing holds great promise for communicating and computing data efficiently. However, scaling current photonic implementation approaches to larger system size remains an outstanding challenge for realizing disruptive quantum technology. Two main ingredients of quantum information processors are quantum interference and single-photon detectors. Here we develop a hybrid superconducting-photonic circuit system to show how these elements can be combined in a scalable fashion on a silicon chip. We demonstrate the suitability of this approach for integrated quantum optics by interfering and detecting photon pairs directly on the chip with waveguide-coupled single-photon detectors. Using a directional coupler implemented with silicon nitride nanophotonic waveguides, we observe 97% interference visibility when measuring photon statistics with two monolithically integrated superconducting single-photon detectors. The photonic circuit and detector fabrication processes are compatible with standard semiconductor thin-film technology, making it possible to implement more complex and larger scale quantum photonic circuits on silicon chips.

Integrated analysis of the effects of agricultural management on nitrogen fluxes at landscape scale.

PubMed

Kros, J; Frumau, K F A; Hensen, A; de Vries, W

2011-11-01

The integrated modelling system INITIATOR was applied to a landscape in the northern part of the Netherlands to assess current nitrogen fluxes to air and water and the impact of various agricultural measures on these fluxes, using spatially explicit input data on animal numbers, land use, agricultural management, meteorology and soil. Average model results on NH(3) deposition and N concentrations in surface water appear to be comparable to observations, but the deviation can be large at local scale, despite the use of high resolution data. Evaluated measures include: air scrubbers reducing NH(3) emissions from poultry and pig housing systems, low protein feeding, reduced fertilizer amounts and low-emission stables for cattle. Low protein feeding and restrictive fertilizer application had the largest effect on both N inputs and N losses, resulting in N deposition reductions on Natura 2000 sites of 10% and 12%, respectively. Copyright © 2011 Elsevier Ltd. All rights reserved.

A scalable silicon photonic chip-scale optical switch for high performance computing systems.

PubMed

Yu, Runxiang; Cheung, Stanley; Li, Yuliang; Okamoto, Katsunari; Proietti, Roberto; Yin, Yawei; Yoo, S J B

2013-12-30

This paper discusses the architecture and provides performance studies of a silicon photonic chip-scale optical switch for scalable interconnect network in high performance computing systems. The proposed switch exploits optical wavelength parallelism and wavelength routing characteristics of an Arrayed Waveguide Grating Router (AWGR) to allow contention resolution in the wavelength domain. Simulation results from a cycle-accurate network simulator indicate that, even with only two transmitter/receiver pairs per node, the switch exhibits lower end-to-end latency and higher throughput at high (>90%) input loads compared with electronic switches. On the device integration level, we propose to integrate all the components (ring modulators, photodetectors and AWGR) on a CMOS-compatible silicon photonic platform to ensure a compact, energy efficient and cost-effective device. We successfully demonstrate proof-of-concept routing functions on an 8 × 8 prototype fabricated using foundry services provided by OpSIS-IME.

Supporting shared decision making beyond consumer-prescriber interactions: Initial development of the CommonGround fidelity scale

PubMed Central

Fukui, Sadaaki; Salyers, Michelle P.; Rapp, Charlie; Goscha, Rick; Young, Leslie; Mabry, Ally

2015-01-01

Shared decision-making has become a central tenet of recovery-oriented, person-centered mental health care, yet the practice is not always transferred to the routine psychiatric visit. Supporting the practice at the system level, beyond the interactions of consumers and medication prescribers, is needed for successful adoption of shared decision-making. CommonGround is a systemic approach, intended to be part of a larger integration of shared decision-making tools and practices at the system level. We discuss the organizational components that CommonGround uses to facilitate shared decision-making, and we present a fidelity scale to assess how well the system is being implemented. PMID:28090194

Crossing disciplines and scales to understand the critical zone

USGS Publications Warehouse

Brantley, S.L.; Goldhaber, M.B.; Vala, Ragnarsdottir K.

2007-01-01

The Critical Zone (CZ) is the system of coupled chemical, biological, physical, and geological processes operating together to support life at the Earth's surface. While our understanding of this zone has increased over the last hundred years, further advance requires scientists to cross disciplines and scales to integrate understanding of processes in the CZ, ranging in scale from the mineral-water interface to the globe. Despite the extreme heterogeneities manifest in the CZ, patterns are observed at all scales. Explanations require the use of new computational and analytical tools, inventive interdisciplinary approaches, and growing networks of sites and people.

Management tools for R&D engineering projects: Coordination perspective for large international consortium (NeXOS)

NASA Astrophysics Data System (ADS)

Castro, Ayoze; Memè, Simone; Quevedo, Eduardo; Waldmann, Christoph; Pearlman, Jay; Delory, Eric; Llinás, Octavio

2017-04-01

NeXOS is a cross-functional and multidisciplinary project funded under the EU FP7 Program, which involves 21 organizations from six different European countries. They all have different backgrounds, interests, business models and perspectives. To be successful, NeXOS applied an international recognized management methodology tailored to the specific project's environment and conditions, with an explicit structure based on defined roles and responsibilities for the people involved in the project and a means for effective communication between them (Fig.1). The project, divided in four different stages of requirements, design, integration, validation and demonstration, allows a clearer monitor of its progress, a comparison of the level of achievement in accordance with the plan and an earlier detection of problems/issues, leading to implementation of less disruptive, but still effective corrective actions. NeXOS is following an ambitious plan to develop innovative sensor systems with a high degree of modularity and interoperability, starting with requirements definition through validation and demonstration phase. To make this integrative approach possible, a management development strategy has been used incorporating systems engineering methods (Fig.2). Although this is standard practice in software development and large scale systems such as aircraft production, it is still new in the ocean hardware business and therefore NeXOS was a test case for this development concept. The question is one of scale as ocean observation systems are typically built on the scale of a few with co-located teams. With a system of diverse technologies (optical, acoustic, platform interfaces), there are cultural differences that must be bridged. The greatest challenge is in the implementation and the willingness of different teams to work with an engineering process, which may help ultimate system integration, but may place additional burdens on individual participants. This presentation will address approaches for effective operations in this environment.

Cholesky-decomposed density MP2 with density fitting: Accurate MP2 and double-hybrid DFT energies for large systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maurer, Simon A.; Clin, Lucien; Ochsenfeld, Christian, E-mail: christian.ochsenfeld@uni-muenchen.de

2014-06-14

Our recently developed QQR-type integral screening is introduced in our Cholesky-decomposed pseudo-densities Møller-Plesset perturbation theory of second order (CDD-MP2) method. We use the resolution-of-the-identity (RI) approximation in combination with efficient integral transformations employing sparse matrix multiplications. The RI-CDD-MP2 method shows an asymptotic cubic scaling behavior with system size and a small prefactor that results in an early crossover to conventional methods for both small and large basis sets. We also explore the use of local fitting approximations which allow to further reduce the scaling behavior for very large systems. The reliability of our method is demonstrated on test sets formore » interaction and reaction energies of medium sized systems and on a diverse selection from our own benchmark set for total energies of larger systems. Timings on DNA systems show that fast calculations for systems with more than 500 atoms are feasible using a single processor core. Parallelization extends the range of accessible system sizes on one computing node with multiple cores to more than 1000 atoms in a double-zeta basis and more than 500 atoms in a triple-zeta basis.« less

Engineering large-scale agent-based systems with consensus

NASA Technical Reports Server (NTRS)

Bokma, A.; Slade, A.; Kerridge, S.; Johnson, K.

1994-01-01

The paper presents the consensus method for the development of large-scale agent-based systems. Systems can be developed as networks of knowledge based agents (KBA) which engage in a collaborative problem solving effort. The method provides a comprehensive and integrated approach to the development of this type of system. This includes a systematic analysis of user requirements as well as a structured approach to generating a system design which exhibits the desired functionality. There is a direct correspondence between system requirements and design components. The benefits of this approach are that requirements are traceable into design components and code thus facilitating verification. The use of the consensus method with two major test applications showed it to be successful and also provided valuable insight into problems typically associated with the development of large systems.

Calendar of Selected Aeronautical and Space Meetings (Calendrier des Manifestations Aeronautiques et Spatiales (Selection)).

DTIC Science & Technology

1983-01-01

Physique de l’Atmosphire et Environnement terrestre 71 09 - Information, Documentation et Informatique 74 10 - Thimes gin~raux (pluridisciplinaires) et...March Louisiana (US) Fiber Communication Optical Communications IEEE Fibre Optics Electro-Optics 02-08 7-9 March Baden-Baden VDE -IEEE Specialists...Conference on Very Large Electronic Systems VDE (GE) Scale Integrated Circuits Solid State Devices IEEE Integrated Circuits Engineering Design Fabrication

Intrarater and interrater reliability and validity in the assessment of the mechanism of injury and integrity of the posterior ligamentous complex: a novel injury severity scoring system for thoracolumbar injuries. Invited submission from the Joint Section Meeting On Disorders of the Spine and Peripheral Nerves, March 2005.

PubMed

Harrop, James S; Vaccaro, Alexander R; Hurlbert, R John; Wilsey, Jared T; Baron, Eli M; Shaffrey, Christopher I; Fisher, Charles G; Dvorak, Marcel F; Oner, F C; Wood, Kirkham B; Anand, Neel; Anderson, D Greg; Lim, Moe R; Lee, Joon Y; Bono, Christopher M; Arnold, Paul M; Rampersaud, Y Raja; Fehlings, Michael G

2006-02-01

A new classification and treatment algorithm for thoracolumbar injuries was recently introduced by Vaccaro and colleagues in 2005. A thoracolumbar injury severity scale (TLISS) was proposed for grading and guiding treatment for these injuries. The scale is based on the following: 1) the mechanism of injury; 2) the integrity of the posterior ligamentous complex (PLC); and 3) the patient's neurological status. The reliability and validity of assessing injury mechanism and the integrity of the PLC was assessed. Forty-eight spine surgeons, consisting of neurosurgeons and orthopedic surgeons, reviewed 56 clinical thoracolumbar injury case histories. Each was classified and scored to determine treatment recommendations according to a novel classification system. After 3 months the case histories were reordered and the physicians repeated the exercise. Validity of this classification was good among reviewers; the vast majority (> 90%) agreed with the system's treatment recommendations. Surgeons were unclear as to a cogent description of PLC disruption and fracture mechanism. The TLISS demonstrated acceptable reliability in terms of intra- and interobserver agreement on the algorithm's treatment recommendations. Replacing injury mechanism with a description of injury morphology and better definition of PLC injury will improve inter- and intraobserver reliability of this injury classification system.

Development of an Unmanned Aerial System (UAS) for Scaling Terrestrial Ecosystem Traits

NASA Astrophysics Data System (ADS)

Meng, R.; McMahon, A. M.; Serbin, S.; Rogers, A.

2015-12-01

The next generation of Ecosystem and Earth System Models (EESMs) will require detailed information on ecosystem structure and function, including properties of vegetation related to carbon (C), water, and energy cycling, in order to project the future state of ecosystems. High spatial-temporal resolution measurements of terrestrial ecosystem are also important for EESMs, because they can provide critical inputs and benchmark datasets for evaluation of EESMs simulations across scales. The recent development of high-quality, low-altitude remote sensing platforms or small UAS (< 25 kg) enables measurements of terrestrial ecosystems at unprecedented temporal and spatial scales. Specifically, these new platforms can provide detailed information on patterns and processes of terrestrial ecosystems at a critical intermediate scale between point measurements and suborbital and satellite platforms. Given their potential for sub-decimeter spatial resolution, improved mission safety, high revisit frequency, and reduced operation cost, these platforms are of particular interest in the development of ecological scaling algorithms to parameterize and benchmark EESMs, particularly over complex and remote terrain. Our group is developing a small UAS platform and integrated sensor package focused on measurement needs for scaling and informing ecosystem modeling activities, as well as scaling and mapping plant functional traits. To do this we are developing an integrated software workflow and hardware package using off-the-shelf instrumentation including a high-resolution digital camera for Structure from Motion, spectroradiometer, and a thermal infrared camera. Our workflow includes platform design, measurement, image processing, data management, and information extraction. The fusion of 3D structure information, thermal-infrared imagery, and spectroscopic measurements, will provide a foundation for the development of ecological scaling and mapping algorithms. Our initial focus is in temperate forests but near-term research will expand into the high-arctic and eventually tropical systems. The results of this prototype study show that off-the-shelf technology can be used to develop a low-cost alternative for mapping plant traits and three-dimensional structure for ecological research.

Capture of fixation by rotational flow; a deterministic hypothesis regarding scaling and stochasticity in fixational eye movements

PubMed Central

Wilkinson, Nicholas M.; Metta, Giorgio

2014-01-01

Visual scan paths exhibit complex, stochastic dynamics. Even during visual fixation, the eye is in constant motion. Fixational drift and tremor are thought to reflect fluctuations in the persistent neural activity of neural integrators in the oculomotor brainstem, which integrate sequences of transient saccadic velocity signals into a short term memory of eye position. Despite intensive research and much progress, the precise mechanisms by which oculomotor posture is maintained remain elusive. Drift exhibits a stochastic statistical profile which has been modeled using random walk formalisms. Tremor is widely dismissed as noise. Here we focus on the dynamical profile of fixational tremor, and argue that tremor may be a signal which usefully reflects the workings of oculomotor postural control. We identify signatures reminiscent of a certain flavor of transient neurodynamics; toric traveling waves which rotate around a central phase singularity. Spiral waves play an organizational role in dynamical systems at many scales throughout nature, though their potential functional role in brain activity remains a matter of educated speculation. Spiral waves have a repertoire of functionally interesting dynamical properties, including persistence, which suggest that they could in theory contribute to persistent neural activity in the oculomotor postural control system. Whilst speculative, the singularity hypothesis of oculomotor postural control implies testable predictions, and could provide the beginnings of an integrated dynamical framework for eye movements across scales. PMID:24616670

Integrated lung tissue mechanics one piece at a time: Computational modeling across the scales of biology.

PubMed

Burrowes, Kelly S; Iravani, Amin; Kang, Wendy

2018-01-12

The lung is a delicately balanced and highly integrated mechanical system. Lung tissue is continuously exposed to the environment via the air we breathe, making it susceptible to damage. As a consequence, respiratory diseases present a huge burden on society and their prevalence continues to rise. Emergent function is produced not only by the sum of the function of its individual components but also by the complex feedback and interactions occurring across the biological scales - from genes to proteins, cells, tissue and whole organ - and back again. Computational modeling provides the necessary framework for pulling apart and putting back together the pieces of the body and organ systems so that we can fully understand how they function in both health and disease. In this review, we discuss models of lung tissue mechanics spanning from the protein level (the extracellular matrix) through to the level of cells, tissue and whole organ, many of which have been developed in isolation. This is a vital step in the process but to understand the emergent behavior of the lung, we must work towards integrating these component parts and accounting for feedback across the scales, such as mechanotransduction. These interactions will be key to unlocking the mechanisms occurring in disease and in seeking new pharmacological targets and improving personalized healthcare. Copyright © 2018 Elsevier Ltd. All rights reserved.

All is not loss: plant biodiversity in the anthropocene.

PubMed

Ellis, Erle C; Antill, Erica C; Kreft, Holger

2012-01-01

Anthropogenic global changes in biodiversity are generally portrayed in terms of massive native species losses or invasions caused by recent human disturbance. Yet these biodiversity changes and others caused directly by human populations and their use of land tend to co-occur as long-term biodiversity change processes in the Anthropocene. Here we explore contemporary anthropogenic global patterns in vascular plant species richness at regional landscape scales by combining spatially explicit models and estimates for native species loss together with gains in exotics caused by species invasions and the introduction of agricultural domesticates and ornamental exotic plants. The patterns thus derived confirm that while native losses are likely significant across at least half of Earth's ice-free land, model predictions indicate that plant species richness has increased overall in most regional landscapes, mostly because species invasions tend to exceed native losses. While global observing systems and models that integrate anthropogenic species loss, introduction and invasion at regional landscape scales remain at an early stage of development, integrating predictions from existing models within a single assessment confirms their vast global extent and significance while revealing novel patterns and their potential drivers. Effective global stewardship of plant biodiversity in the Anthropocene will require integrated frameworks for observing, modeling and forecasting the different forms of anthropogenic biodiversity change processes at regional landscape scales, towards conserving biodiversity within the novel plant communities created and sustained by human systems.

All Is Not Loss: Plant Biodiversity in the Anthropocene

PubMed Central

Ellis, Erle C.; Antill, Erica C.; Kreft, Holger

2012-01-01

Anthropogenic global changes in biodiversity are generally portrayed in terms of massive native species losses or invasions caused by recent human disturbance. Yet these biodiversity changes and others caused directly by human populations and their use of land tend to co-occur as long-term biodiversity change processes in the Anthropocene. Here we explore contemporary anthropogenic global patterns in vascular plant species richness at regional landscape scales by combining spatially explicit models and estimates for native species loss together with gains in exotics caused by species invasions and the introduction of agricultural domesticates and ornamental exotic plants. The patterns thus derived confirm that while native losses are likely significant across at least half of Earth's ice-free land, model predictions indicate that plant species richness has increased overall in most regional landscapes, mostly because species invasions tend to exceed native losses. While global observing systems and models that integrate anthropogenic species loss, introduction and invasion at regional landscape scales remain at an early stage of development, integrating predictions from existing models within a single assessment confirms their vast global extent and significance while revealing novel patterns and their potential drivers. Effective global stewardship of plant biodiversity in the Anthropocene will require integrated frameworks for observing, modeling and forecasting the different forms of anthropogenic biodiversity change processes at regional landscape scales, towards conserving biodiversity within the novel plant communities created and sustained by human systems. PMID:22272360

An Overview of NASA Efforts on Zero Boiloff Storage of Cryogenic Propellants

NASA Technical Reports Server (NTRS)

Hastings, Leon J.; Plachta, D. W.; Salerno, L.; Kittel, P.; Haynes, Davy (Technical Monitor)

2001-01-01

Future mission planning within NASA has increasingly motivated consideration of cryogenic propellant storage durations on the order of years as opposed to a few weeks or months. Furthermore, the advancement of cryocooler and passive insulation technologies in recent years has substantially improved the prospects for zero boiloff storage of cryogenics. Accordingly, a cooperative effort by NASA's Ames Research Center (ARC), Glenn Research Center (GRC), and Marshall Space Flight Center (MSFC) has been implemented to develop and demonstrate "zero boiloff" concepts for in-space storage of cryogenic propellants, particularly liquid hydrogen and oxygen. ARC is leading the development of flight-type cryocoolers, GRC the subsystem development and small scale testing, and MSFC the large scale and integrated system level testing. Thermal and fluid modeling involves a combined effort by the three Centers. Recent accomplishments include: 1) development of "zero boiloff" analytical modeling techniques for sizing the storage tankage, passive insulation, cryocooler, power source mass, and radiators; 2) an early subscale demonstration with liquid hydrogen 3) procurement of a flight-type 10 watt, 95 K pulse tube cryocooler for liquid oxygen storage and 4) assembly of a large-scale test article for an early demonstration of the integrated operation of passive insulation, destratification/pressure control, and cryocooler (commercial unit) subsystems to achieve zero boiloff storage of liquid hydrogen. Near term plans include the large-scale integrated system demonstration testing this summer, subsystem testing of the flight-type pulse-tube cryocooler with liquid nitrogen (oxygen simulant), and continued development of a flight-type liquid hydrogen pulse tube cryocooler.

15x optical zoom and extreme optical image stabilisation: diffraction limited integral field spectroscopy with the Oxford SWIFT spectrograph

NASA Astrophysics Data System (ADS)

Tecza, Matthias; Thatte, Niranjan; Clarke, Fraser; Lynn, James; Freeman, David; Roberts, Jennifer; Dekany, Richard

2012-09-01

When commissioned in November 2008 at the Palomar 200 inch Hale Telescope, the Oxford SWIFT I and z band integral field spectrograph, fed by the adaptive optics system PALAO, provided a wide (3×) range of spatial resolutions: three plate scales of 235 mas, 160 mas, and 80 mas per spaxel over a contiguous field-of-view of 89×44 pixels. Depending on observing conditions and guide star brightness we can choose a seeing limited scale of 235 mas per spaxel, or 160 mas and 80 mas per spaxel for very bright guide star AO with substantial increase of enclosed energy. Over the last two years PALAO was upgraded to PALM-3000: an extreme, high-order adaptive optics system with two deformable mirrors with more than 3000 actuators, promising diffraction limited performance in SWIFT's wavelength range. In order to take advantage of this increased spatial resolution we upgraded SWIFT with new pre-optics allowing us to spatially Nyquist sample the diffraction limited PALM-3000 point spread function with 16 mas resolution, reducing the spaxel scale by another factor of 5×. We designed, manufactured, integrated and tested the new pre-optics in the first half of 2011 and commissioned it in December 2011. Here we present the opto-mechanical design and assembly of the new scale changing optics, as well as laboratory and on-sky commissioning results. In optimal observing conditions we achieve substantial Strehl ratios, delivering the near diffraction limited spatial resolution in the I and z bands.

Modeling systems-level dynamics: Understanding without mechanistic explanation in integrative systems biology.

PubMed

MacLeod, Miles; Nersessian, Nancy J

2015-02-01

In this paper we draw upon rich ethnographic data of two systems biology labs to explore the roles of explanation and understanding in large-scale systems modeling. We illustrate practices that depart from the goal of dynamic mechanistic explanation for the sake of more limited modeling goals. These processes use abstract mathematical formulations of bio-molecular interactions and data fitting techniques which we call top-down abstraction to trade away accurate mechanistic accounts of large-scale systems for specific information about aspects of those systems. We characterize these practices as pragmatic responses to the constraints many modelers of large-scale systems face, which in turn generate more limited pragmatic non-mechanistic forms of understanding of systems. These forms aim at knowledge of how to predict system responses in order to manipulate and control some aspects of them. We propose that this analysis of understanding provides a way to interpret what many systems biologists are aiming for in practice when they talk about the objective of a "systems-level understanding." Copyright © 2014 Elsevier Ltd. All rights reserved.

Data Movement Dominates: Advanced Memory Technology to Address the Real Exascale Power Problem

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bergman, Keren

Energy is the fundamental barrier to Exascale supercomputing and is dominated by the cost of moving data from one point to another, not computation. Similarly, performance is dominated by data movement, not computation. The solution to this problem requires three critical technologies: 3D integration, optical chip-to-chip communication, and a new communication model. The central goal of the Sandia led "Data Movement Dominates" project aimed to develop memory systems and new architectures based on these technologies that have the potential to lower the cost of local memory accesses by orders of magnitude and provide substantially more bandwidth. Only through these transformationalmore » advances can future systems reach the goals of Exascale computing with a manageable power budgets. The Sandia led team included co-PIs from Columbia University, Lawrence Berkeley Lab, and the University of Maryland. The Columbia effort of Data Movement Dominates focused on developing a physically accurate simulation environment and experimental verification for optically-connected memory (OCM) systems that can enable continued performance scaling through high-bandwidth capacity, energy-efficient bit-rate transparency, and time-of-flight latency. With OCM, memory device parallelism and total capacity can scale to match future high-performance computing requirements without sacrificing data-movement efficiency. When we consider systems with integrated photonics, links to memory can be seamlessly integrated with the interconnection network-in a sense, memory becomes a primary aspect of the interconnection network. At the core of the Columbia effort, toward expanding our understanding of OCM enabled computing we have created an integrated modeling and simulation environment that uniquely integrates the physical behavior of the optical layer. The PhoenxSim suite of design and software tools developed under this effort has enabled the co-design of and performance evaluation photonics-enabled OCM architectures on Exascale computing systems.« less

On-chip synthesis of circularly polarized emission of light with integrated photonic circuits.

PubMed

He, Li; Li, Mo

2014-05-01

The helicity of circularly polarized (CP) light plays an important role in the light-matter interaction in magnetic and quantum material systems. Exploiting CP light in integrated photonic circuits could lead to on-chip integration of novel optical helicity-dependent devices for applications ranging from spintronics to quantum optics. In this Letter, we demonstrate a silicon photonic circuit coupled with a 2D grating emitter operating at a telecom wavelength to synthesize vertically emitting, CP light from a quasi-TE waveguide mode. Handedness of the emitted circular polarized light can be thermally controlled with an integrated microheater. The compact device footprint enables a small beam diameter, which is desirable for large-scale integration.

The fast multipole method and point dipole moment polarizable force fields.

PubMed

Coles, Jonathan P; Masella, Michel

2015-01-14

We present an implementation of the fast multipole method for computing Coulombic electrostatic and polarization forces from polarizable force-fields based on induced point dipole moments. We demonstrate the expected O(N) scaling of that approach by performing single energy point calculations on hexamer protein subunits of the mature HIV-1 capsid. We also show the long time energy conservation in molecular dynamics at the nanosecond scale by performing simulations of a protein complex embedded in a coarse-grained solvent using a standard integrator and a multiple time step integrator. Our tests show the applicability of fast multipole method combined with state-of-the-art chemical models in molecular dynamical systems.

Low Activity Waste Pretreatment System Bench-Scale Testing: Supporting Integrated Testing and Facility Safety Analyses - 17171

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schonewill, Philip P.; Russell, Renee L.; Daniel, Richard C.

The Low Activity Waste Pretreatment System (LAWPS) is being designed to enable the direct feed of waste to the Hanford Tank Waste Treatment and Immobilization Plant (WTP) Low Activity Waste (LAW) facility to be immobilized. Prior to construction of the LAWPS, pilot-scale integrated testing of the key unit operations (crossflow filtration, ion exchange using spherical resorcinol-formaldehyde (sRF) resin) will be conducted by a team led by Washington River Protection Solutions (WRPS) to increase the technology maturation level of the facility’s critical technology elements. As a part of this effort, Pacific Northwest National Laboratory (PNNL) has conducted a series of bench-scalemore » (or engineering-scale) tests to perform two major objectives: (1) support pilot-scale integrated testing of the LAWPS by supplying information or performance data in advance of operating the pilot-scale facility; and (2) collect data needed to establish or confirm assumptions/approaches planned for implementation in the LAWPS safety basis. The first objective was focused in two technical areas: developing simulants that are representative of expected waste feed and can be produced at larger scales, and using these simulants in a bench-scale crossflow filter to establish expected solid-liquid separation performance. The crossflow filter was also used to observe the efficacy (with respect to filter production rate) of selected operational strategies. The second objective also included two technical areas: measuring the effect of sRF resin on hydrogen generation rate under irradiation, and demonstrating that the planned hydrogen management approach is effective and robust. The hydrogen management strategy involves fluidization of the sRF resin bed in the ion exchange columns and recirculating the liquid, a scenario that is planned for testing at full column height. The full height tests at PNNL also supported full-scale IX column testing conducted as part of the technology maturation plan. The experimental approaches used at PNNL in these four technical areas are summarized and selected key preliminary results are provided.« less